## Fri Feb 20 02:03:45 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/XH1_bin.25.fa -m mmseqs --output XH1_bin.25 --output_dir /data/result/bins/wyx/eggqs50+/XH1_bin.25 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
XH1_k127_1048638_0	1047013.AQSP01000138_gene1019	1.824e-62	222.0	COG0546@1|root,COG0546@2|Bacteria,2NPKQ@2323|unclassified Bacteria	2|Bacteria	S	Haloacid dehalogenase-like hydrolase	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
XH1_k127_1048638_1	1041930.Mtc_2428	1.964e-55	201.0	COG1853@1|root,arCOG02016@2157|Archaea,2Y0GX@28890|Euryarchaeota,2NASY@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
XH1_k127_1048638_2	575540.Isop_3007	2.925e-30	128.0	COG0727@1|root,COG0727@2|Bacteria,2IZM1@203682|Planctomycetes	203682|Planctomycetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
XH1_k127_1048638_3	643648.Slip_0675	6.747e-26	108.0	COG2768@1|root,COG2768@2|Bacteria,1VET2@1239|Firmicutes,24QUH@186801|Clostridia,42K86@68298|Syntrophomonadaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	fdxA	GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114	-	-	-	-	-	-	-	-	-	-	Fer4
XH1_k127_1048638_4	1232410.KI421413_gene671	7.143e-20	92.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,42TK0@68525|delta/epsilon subdivisions,2WQ5D@28221|Deltaproteobacteria,43V44@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
XH1_k127_1062080_2	1121405.dsmv_2949	2.083e-78	267.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,2MJ2V@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
XH1_k127_1062080_0	909663.KI867150_gene1592	6.459e-140	451.0	COG0171@1|root,COG0171@2|Bacteria,1QHZ4@1224|Proteobacteria,42QD8@68525|delta/epsilon subdivisions,2WMK9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
XH1_k127_1062080_4	933262.AXAM01000037_gene876	4.28e-16	80.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,42VU0@68525|delta/epsilon subdivisions,2WRU6@28221|Deltaproteobacteria,2MP8W@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
XH1_k127_1062080_1	880073.Calab_1595	3.472e-132	438.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
XH1_k127_1062080_3	933262.AXAM01000037_gene877	1.238e-17	84.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,42Q26@68525|delta/epsilon subdivisions,2WPER@28221|Deltaproteobacteria,2MM4H@213118|Desulfobacterales	28221|Deltaproteobacteria	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1072653_0	515635.Dtur_1391	1.385e-185	594.0	COG0587@1|root,COG0587@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
XH1_k127_1111173_1	1076550.LH22_09385	3.447e-15	76.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,3VZ2Y@53335|Pantoea	1236|Gammaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446	Anticodon_1,tRNA-synt_1g,tRNA_bind
XH1_k127_1111173_0	572546.Arcpr_0668	3.702e-134	442.0	COG0477@1|root,arCOG00143@2157|Archaea,2XUTR@28890|Euryarchaeota,245RD@183980|Archaeoglobi	183980|Archaeoglobi	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
XH1_k127_1111518_0	338966.Ppro_1737	4.309e-59	211.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
XH1_k127_1111518_1	1313265.JNIE01000002_gene929	3.988e-09	68.0	COG0701@1|root,COG0701@2|Bacteria,2G59X@200783|Aquificae	200783|Aquificae	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
XH1_k127_111652_3	519989.ECTPHS_01334	8.65e-29	129.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1WX4I@135613|Chromatiales	135613|Chromatiales	D	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
XH1_k127_111652_4	1238450.VIBNISOn1_620020	5.383e-16	89.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1XUCE@135623|Vibrionales	135623|Vibrionales	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
XH1_k127_111652_2	1209989.TepiRe1_1785	4.094e-57	205.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,42EW3@68295|Thermoanaerobacterales	186801|Clostridia	D	TIGRFAM Cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
XH1_k127_111652_5	1205910.B005_4774	2.324e-06	57.0	COG1396@1|root,COG1396@2|Bacteria,2GN0H@201174|Actinobacteria,4EMX7@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
XH1_k127_111652_0	56780.SYN_02832	7.609e-87	300.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,42NKR@68525|delta/epsilon subdivisions,2WJIQ@28221|Deltaproteobacteria,2MQRY@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	FlhB HrpN YscU SpaS Family	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
XH1_k127_111652_1	404380.Gbem_3767	1.689e-79	270.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2WIWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
XH1_k127_1122119_0	96561.Dole_2191	8.104e-287	906.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,2MI4X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM formate C-acetyltransferase glycine radical	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
XH1_k127_1148692_3	56780.SYN_02121	1.73e-74	258.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MQEZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
XH1_k127_1148692_0	264732.Moth_1625	9.39e-120	392.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
XH1_k127_1148692_4	469617.FUAG_02796	4.452e-61	220.0	COG0834@1|root,COG0834@2|Bacteria,378TP@32066|Fusobacteria	32066|Fusobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
XH1_k127_1148692_1	485915.Dret_1293	2.922e-112	372.0	COG0765@1|root,COG0765@2|Bacteria,1MWF0@1224|Proteobacteria,42Q80@68525|delta/epsilon subdivisions,2X5YY@28221|Deltaproteobacteria,2MGXR@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
XH1_k127_1148692_2	1379281.AVAG01000092_gene592	3.037e-109	365.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42PN3@68525|delta/epsilon subdivisions,2WMAE@28221|Deltaproteobacteria,2MA45@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
XH1_k127_1148692_5	1333998.M2A_1452	6.116e-49	183.0	COG4690@1|root,COG4690@2|Bacteria,1RBRZ@1224|Proteobacteria,2U9EN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1153140_1	1121430.JMLG01000013_gene1880	1.46e-65	229.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,260TY@186807|Peptococcaceae	186801|Clostridia	C	Aconitase family (aconitate hydratase)	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
XH1_k127_1153140_0	56780.SYN_02557	1.518e-184	587.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2MQ68@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
XH1_k127_1153140_2	858215.Thexy_1529	2.181e-40	156.0	COG4720@1|root,COG4720@2|Bacteria,1VF2R@1239|Firmicutes,24QR3@186801|Clostridia,42GI9@68295|Thermoanaerobacterales	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
XH1_k127_1171315_7	56780.SYN_02930	7.635e-12	68.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MR6X@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
XH1_k127_1171315_6	1278073.MYSTI_03802	2.409e-28	120.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,2YV84@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1171315_2	1125863.JAFN01000001_gene2998	1.432e-55	205.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2WN91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
XH1_k127_1171315_3	1184267.A11Q_2051	3.169e-43	175.0	COG1352@1|root,COG1352@2|Bacteria,1QY2J@1224|Proteobacteria,43AK1@68525|delta/epsilon subdivisions,2MTJG@213481|Bdellovibrionales,2X60B@28221|Deltaproteobacteria	213481|Bdellovibrionales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1171315_4	667014.Thein_0398	2.014e-32	132.0	COG1386@1|root,COG1386@2|Bacteria,2GH88@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
XH1_k127_1171315_5	1123371.ATXH01000001_gene1203	5.738e-32	134.0	COG1354@1|root,COG1354@2|Bacteria,2GI6S@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	D	Segregation and condensation protein ScpA	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
XH1_k127_1171315_0	555779.Dthio_PD1672	3.422e-123	413.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria,2M9JW@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
XH1_k127_1171315_1	706587.Desti_2440	3.759e-62	220.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,2MQJ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
XH1_k127_1198708_0	96561.Dole_1470	1.318e-205	676.0	COG0457@1|root,COG2203@1|root,COG2204@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43BR8@68525|delta/epsilon subdivisions,2X724@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
XH1_k127_1198708_1	1294142.CINTURNW_4046	1.434e-85	298.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
XH1_k127_1198708_2	1125863.JAFN01000001_gene89	1.665e-44	176.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
XH1_k127_1209981_11	56780.SYN_00074	6.103e-42	159.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
XH1_k127_1209981_2	589865.DaAHT2_0354	5.595e-106	355.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2MI9X@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
XH1_k127_1209981_10	1208583.COMX_06465	5.655e-46	169.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2U5B5@28211|Alphaproteobacteria,2JRR2@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
XH1_k127_1209981_8	469378.Ccur_01710	1.641e-55	197.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4CVR4@84998|Coriobacteriia	84998|Coriobacteriia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
XH1_k127_1209981_15	1167006.UWK_01717	5.133e-24	104.0	COG4392@1|root,COG4392@2|Bacteria,1NEQP@1224|Proteobacteria,42VHX@68525|delta/epsilon subdivisions,2WRER@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
XH1_k127_1209981_7	243231.GSU0768	5.204e-57	207.0	COG1296@1|root,COG1296@2|Bacteria,1P6U3@1224|Proteobacteria,42QVQ@68525|delta/epsilon subdivisions,2WMW1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM AzlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
XH1_k127_1209981_9	1131269.AQVV01000016_gene1841	1.62e-46	179.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
XH1_k127_1209981_12	941449.dsx2_0755	4.705e-37	160.0	COG1639@1|root,COG4191@1|root,COG1639@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria,2MAB3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein, response regulator receiver, histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD,HisKA,Response_reg
XH1_k127_1209981_3	1121468.AUBR01000029_gene1577	8.101e-106	357.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,42FDK@68295|Thermoanaerobacterales	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
XH1_k127_1209981_1	316067.Geob_2401	1.782e-213	691.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
XH1_k127_1209981_0	1232410.KI421414_gene2883	2.218e-229	730.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,43SZI@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
XH1_k127_1209981_16	526222.Desal_0665	1.682e-18	86.0	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria,2MD8Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
XH1_k127_1209981_6	472759.Nhal_3192	8.27e-73	246.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,1S3N1@1236|Gammaproteobacteria,1X23J@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
XH1_k127_1209981_14	472759.Nhal_2875	3.856e-31	127.0	2EAWX@1|root,334Y4@2|Bacteria,1P2TY@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1209981_5	138119.DSY4470	3.792e-73	248.0	COG2210@1|root,COG2210@2|Bacteria,1UIFM@1239|Firmicutes,24H1I@186801|Clostridia,266DJ@186807|Peptococcaceae	186801|Clostridia	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
XH1_k127_1209981_13	880073.Calab_2458	3.388e-32	128.0	COG2920@1|root,COG2920@2|Bacteria,2NQ6I@2323|unclassified Bacteria	2|Bacteria	P	DsrC like protein	dsrC	-	1.8.5.4	ko:K11179,ko:K17218	ko00920,ko04122,map00920,map04122	-	R10152	RC03155	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC,Pyr_redox_2
XH1_k127_1209981_4	1121875.KB907546_gene2717	7.033e-91	304.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,1HZW9@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
XH1_k127_1212037_3	335543.Sfum_1842	4e-21	97.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,42MFS@68525|delta/epsilon subdivisions,2WJPR@28221|Deltaproteobacteria,2MRBH@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
XH1_k127_1212037_0	667014.Thein_0499	8.8e-133	437.0	COG0486@1|root,COG0486@2|Bacteria,2GHDZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
XH1_k127_1212037_1	525897.Dbac_0167	3.016e-124	410.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2M8TZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
XH1_k127_1212037_2	944480.ATUV01000001_gene945	7.791e-85	286.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2M7K0@213113|Desulfurellales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
XH1_k127_1236271_0	1121406.JAEX01000025_gene2528	9.047e-94	312.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,42QU8@68525|delta/epsilon subdivisions,2X5Q5@28221|Deltaproteobacteria,2MGUA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
XH1_k127_1236271_1	335543.Sfum_2018	2.685e-76	267.0	COG0491@1|root,COG0491@2|Bacteria,1MW35@1224|Proteobacteria,42RFB@68525|delta/epsilon subdivisions,2WNGT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
XH1_k127_1236271_3	869213.JCM21142_194	1.453e-52	194.0	COG4843@1|root,COG4843@2|Bacteria,4NRH5@976|Bacteroidetes,47PXG@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
XH1_k127_1236271_2	380703.AHA_0990	3.667e-58	214.0	COG0223@1|root,COG0451@1|root,COG0223@2|Bacteria,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria,1Y4ZZ@135624|Aeromonadales	135624|Aeromonadales	I	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides	arnA	-	1.1.1.305,2.1.2.13	ko:K10011	ko00520,ko01503,map00520,map01503	M00721,M00761	R07658,R07660	RC00026,RC01575,RC01812	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,Formyl_trans_C,Formyl_trans_N
XH1_k127_1236271_4	867903.ThesuDRAFT_00016	2.769e-37	151.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3WCZD@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
XH1_k127_1249106_3	909663.KI867150_gene1083	7.147e-52	190.0	COG1693@1|root,COG1693@2|Bacteria,1RAC2@1224|Proteobacteria,42QW9@68525|delta/epsilon subdivisions,2WMZV@28221|Deltaproteobacteria,2MQWZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Ribonuclease R winged-helix domain	-	-	-	ko:K09720	-	-	-	-	ko00000,ko03000	-	-	-	DUF128,HTH_12
XH1_k127_1249106_4	639282.DEFDS_0678	3.432e-33	141.0	COG1335@1|root,COG1335@2|Bacteria,2GFP3@200930|Deferribacteres	200930|Deferribacteres	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
XH1_k127_1249106_0	56780.SYN_02383	0.0	1202.0	COG0574@1|root,COG0574@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2MR7X@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
XH1_k127_1249106_7	1068980.ARVW01000001_gene1755	8.438e-10	61.0	COG0300@1|root,COG0300@2|Bacteria,2I2VP@201174|Actinobacteria,4EBRB@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.102	ko:K04708	ko00600,ko01100,map00600,map01100	M00094,M00099	R02978	RC00089	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short
XH1_k127_1249106_5	269799.Gmet_3486	3.601e-22	99.0	2EFUG@1|root,339KM@2|Bacteria,1NGQQ@1224|Proteobacteria,430N8@68525|delta/epsilon subdivisions,2WVUR@28221|Deltaproteobacteria,43VA8@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Alanine-zipper, major outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Alanine_zipper
XH1_k127_1249106_1	316067.Geob_0133	7.882e-191	604.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,42ZCU@68525|delta/epsilon subdivisions,2WTVT@28221|Deltaproteobacteria,43U8N@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,SPOR,YkuD
XH1_k127_1249106_2	56780.SYN_02183	5.941e-135	436.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42TV7@68525|delta/epsilon subdivisions,2WRW0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,YkuD
XH1_k127_1249106_6	439235.Dalk_1780	2.95e-10	69.0	COG3047@1|root,COG3047@2|Bacteria,1Q8PV@1224|Proteobacteria,437GB@68525|delta/epsilon subdivisions,2X2NY@28221|Deltaproteobacteria,2MP63@213118|Desulfobacterales	2|Bacteria	M	OmpW family	ompW	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K07275,ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OmpW
XH1_k127_1266062_2	404380.Gbem_0755	1.454e-22	109.0	COG1466@1|root,COG1466@2|Bacteria,1RHE9@1224|Proteobacteria,42SNR@68525|delta/epsilon subdivisions,2WP96@28221|Deltaproteobacteria,43TIV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
XH1_k127_1266062_4	56780.SYN_02376	2.571e-12	70.0	COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2WR9I@28221|Deltaproteobacteria,2MSD0@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
XH1_k127_1266062_1	867903.ThesuDRAFT_02281	6.461e-105	353.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WCUJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
XH1_k127_1266062_0	1382304.JNIL01000001_gene1094	1.533e-123	405.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
XH1_k127_1266062_5	439235.Dalk_4008	4.641e-12	72.0	2CI6U@1|root,33N1H@2|Bacteria,1NQ5J@1224|Proteobacteria,42XMU@68525|delta/epsilon subdivisions,2WSUP@28221|Deltaproteobacteria,2MMAA@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1266062_3	290397.Adeh_0651	2.41e-14	83.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
XH1_k127_1280242_2	56780.SYN_01459	5.355e-51	183.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990,ko:K01992,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC2_membrane_3,ABC_tran
XH1_k127_1280242_0	56780.SYN_01457	1.976e-145	471.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
XH1_k127_1280242_1	56780.SYN_01456	1.335e-144	466.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria,2MQ4K@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
XH1_k127_1306005_1	439235.Dalk_3335	3.79e-19	103.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	crtD	-	1.3.99.26,1.3.99.27,1.3.99.28,1.3.99.29,1.3.99.31,5.4.99.9	ko:K01854,ko:K09845,ko:K10027	ko00052,ko00520,ko00906,ko01100,ko01110,map00052,map00520,map00906,map01100,map01110	-	R00505,R04787,R04798,R04800,R07517,R07520,R07523,R07534,R09009,R09691,R09692	RC00317,RC01214,RC02080,RC02088,RC02396,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
XH1_k127_1306005_0	742733.HMPREF9469_05757	2.024e-26	116.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_7
XH1_k127_1306005_2	289376.THEYE_A1607	1.905e-17	90.0	COG0810@1|root,COG0810@2|Bacteria,3J0U0@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
XH1_k127_1319208_0	477974.Daud_1393	9.643e-108	366.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,26133@186807|Peptococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
XH1_k127_1319208_1	316067.Geob_0708	3.902e-58	208.0	COG1502@1|root,COG1502@2|Bacteria,1RG6H@1224|Proteobacteria,43B9U@68525|delta/epsilon subdivisions,2WNMQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
XH1_k127_1331089_1	880073.Calab_2261	3.379e-118	393.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2NNZ0@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
XH1_k127_1331089_0	926550.CLDAP_37780	1.547e-240	760.0	COG0475@1|root,COG0490@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria	2|Bacteria	P	domain protein	MA20_07375	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
XH1_k127_1355488_3	1226994.AMZB01000111_gene1974	1.44e-44	164.0	COG0439@1|root,COG4799@1|root,COG0439@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,1RQ9Q@1236|Gammaproteobacteria,1YF6W@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Biotin carboxylase C-terminal domain	pyc	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
XH1_k127_1355488_0	1121422.AUMW01000009_gene3305	2.801e-147	471.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,266V3@186807|Peptococcaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
XH1_k127_1355488_2	1304885.AUEY01000003_gene483	1.047e-97	325.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,42SY9@68525|delta/epsilon subdivisions,2X5HT@28221|Deltaproteobacteria,2MN08@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
XH1_k127_1355488_1	1121422.AUMW01000009_gene3305	1.337e-139	449.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,266V3@186807|Peptococcaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
XH1_k127_135956_5	56780.SYN_01539	9.963e-41	156.0	COG0589@1|root,COG0589@2|Bacteria,1N9QR@1224|Proteobacteria,42VEI@68525|delta/epsilon subdivisions,2WRFX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
XH1_k127_135956_1	768704.Desmer_2407	2.561e-60	216.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia,261PJ@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
XH1_k127_135956_4	869213.JCM21142_62410	5.436e-42	160.0	COG1051@1|root,COG1051@2|Bacteria,4NP2X@976|Bacteroidetes	976|Bacteroidetes	F	Hydrolase, NUDIX family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,zf-NADH-PPase
XH1_k127_135956_0	649747.HMPREF0083_01561	5.075e-141	461.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HV0C@91061|Bacilli,271MY@186822|Paenibacillaceae	91061|Bacilli	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
XH1_k127_135956_2	880073.Calab_1904	1.632e-46	177.0	COG2834@1|root,COG2834@2|Bacteria,2NQJ8@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
XH1_k127_135956_3	880073.Calab_1905	4.707e-44	179.0	2DC21@1|root,2ZCJ0@2|Bacteria,2NQCS@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_135956_7	439235.Dalk_2767	8.598e-18	94.0	COG1142@1|root,COG1142@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_4,Fer4_6
XH1_k127_1360846_7	78579.XP_003662820.1	2.079e-07	59.0	COG2020@1|root,KOG2628@2759|Eukaryota,38E6W@33154|Opisthokonta,3P25D@4751|Fungi,3QUDT@4890|Ascomycota,2130M@147550|Sordariomycetes,3U50R@5139|Sordariales,3HADU@35718|Chaetomiaceae	4751|Fungi	O	Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family	STE14	GO:0003674,GO:0003824,GO:0003880,GO:0004671,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005637,GO:0005737,GO:0005783,GO:0005789,GO:0006464,GO:0006479,GO:0006481,GO:0006807,GO:0007323,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0010467,GO:0012505,GO:0016020,GO:0016021,GO:0016740,GO:0016741,GO:0018410,GO:0019538,GO:0019866,GO:0031090,GO:0031136,GO:0031137,GO:0031139,GO:0031224,GO:0031965,GO:0031967,GO:0031975,GO:0031984,GO:0032259,GO:0036211,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0043687,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046999,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051604,GO:0051998,GO:0065007,GO:0071432,GO:0071704,GO:0098827,GO:0140096,GO:1901564,GO:2000241,GO:2000243	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	ICMT
XH1_k127_1360846_2	1265505.ATUG01000002_gene2495	1.087e-61	221.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,42X7G@68525|delta/epsilon subdivisions,2WSX9@28221|Deltaproteobacteria,2MM84@213118|Desulfobacterales	28221|Deltaproteobacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NnrU,PEMT
XH1_k127_1360846_6	706587.Desti_1512	2.478e-13	73.0	COG0640@1|root,COG0640@2|Bacteria,1Q62E@1224|Proteobacteria,4329P@68525|delta/epsilon subdivisions,2WYD0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
XH1_k127_1360846_0	909663.KI867150_gene487	1.164e-115	384.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2WKJY@28221|Deltaproteobacteria,2MQC9@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
XH1_k127_1360846_1	768670.Calni_0340	1.246e-74	267.0	COG2067@1|root,COG2067@2|Bacteria,2GFPR@200930|Deferribacteres	200930|Deferribacteres	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
XH1_k127_1360846_4	158190.SpiGrapes_2707	3.611e-41	158.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_1360846_5	1123274.KB899406_gene1197	3.966e-31	128.0	2E4SV@1|root,32ZM7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
XH1_k127_1370068_1	760568.Desku_2934	8.986e-248	777.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,2610M@186807|Peptococcaceae	186801|Clostridia	C	iron hydrogenase, small subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_9,NADH-G_4Fe-4S_3
XH1_k127_1370068_0	580340.Tlie_1465	0.0	1088.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,3TAPD@508458|Synergistetes	508458|Synergistetes	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
XH1_k127_1370068_3	177437.HRM2_16520	3.83e-38	147.0	COG3411@1|root,COG3411@2|Bacteria,1N1N9@1224|Proteobacteria,42U7G@68525|delta/epsilon subdivisions,2WQFG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Ferredoxin	-	-	1.12.1.3	ko:K17992	-	-	-	-	ko00000,ko01000	-	-	-	-
XH1_k127_1370068_2	644282.Deba_1526	7.895e-53	190.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SIE@68525|delta/epsilon subdivisions,2WP8B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
XH1_k127_137956_0	237368.SCABRO_02098	3.177e-223	716.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2IX0T@203682|Planctomycetes	203682|Planctomycetes	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PPDK_N
XH1_k127_137956_2	237368.SCABRO_02097	4.12e-44	166.0	COG0748@1|root,COG0748@2|Bacteria	2|Bacteria	P	coenzyme F420 binding	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Putative_PNPOx
XH1_k127_137956_1	443144.GM21_1432	3.074e-150	506.0	COG2204@1|root,COG3852@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
XH1_k127_1389141_1	96561.Dole_2768	3.66e-33	143.0	2F1H5@1|root,33UHN@2|Bacteria,1NUUT@1224|Proteobacteria,42ZR9@68525|delta/epsilon subdivisions,2WUUD@28221|Deltaproteobacteria,2MN8Q@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1389141_0	96561.Dole_2769	1.815e-81	277.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,2MJS3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
XH1_k127_1442895_5	96561.Dole_1995	2.193e-50	193.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1RCNJ@1224|Proteobacteria,43AF2@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Belongs to the ompA family	oprF	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,OprF,TSP_3
XH1_k127_1442895_0	537970.HCAN_1262	3.25e-183	581.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2YMAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
XH1_k127_1442895_7	56780.SYN_02934	2.228e-39	152.0	COG0622@1|root,COG0622@2|Bacteria,1N8BH@1224|Proteobacteria,42VEB@68525|delta/epsilon subdivisions,2WRII@28221|Deltaproteobacteria,2MS3U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
XH1_k127_1442895_4	1151117.AJLF01000001_gene1707	4.037e-53	191.0	COG0537@1|root,arCOG00419@2157|Archaea,2XWGT@28890|Euryarchaeota,242M1@183968|Thermococci	183968|Thermococci	F	Hit family	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
XH1_k127_1442895_3	266117.Rxyl_2548	7.836e-84	288.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4CPF1@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
XH1_k127_1442895_1	243231.GSU1693	4.466e-148	481.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria,43U89@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	amino acid-binding ACT domain protein	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
XH1_k127_1442895_2	338963.Pcar_1514	1.527e-134	439.0	COG3635@1|root,COG3635@2|Bacteria,1R4TM@1224|Proteobacteria,42NCT@68525|delta/epsilon subdivisions,2WKEG@28221|Deltaproteobacteria,43SUK@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Proposed homoserine kinase	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
XH1_k127_1442895_6	1191523.MROS_2152	1.24e-41	164.0	COG1639@1|root,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
XH1_k127_1442895_8	1121459.AQXE01000002_gene1372	1.558e-21	107.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WMIN@28221|Deltaproteobacteria,2M912@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
XH1_k127_1455911_5	351348.Maqu_1186	1.684e-37	146.0	COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,1SAVX@1236|Gammaproteobacteria,468TW@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
XH1_k127_1455911_4	1232410.KI421422_gene1973	2.571e-38	152.0	2E1K2@1|root,32WXJ@2|Bacteria,1N3MI@1224|Proteobacteria,42UCI@68525|delta/epsilon subdivisions,2WR06@28221|Deltaproteobacteria,43VIJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1455911_3	1382304.JNIL01000001_gene1429	1.259e-79	283.0	COG1042@1|root,COG1042@2|Bacteria,1TPTQ@1239|Firmicutes,4HCHN@91061|Bacilli	91061|Bacilli	C	Succinyl-CoA ligase like flavodoxin domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
XH1_k127_1455911_1	866895.HBHAL_1326	1.461e-101	339.0	COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,3NEHQ@45667|Halobacillus	91061|Bacilli	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
XH1_k127_1455911_0	1499967.BAYZ01000102_gene3560	9.912e-144	466.0	COG1092@1|root,COG1092@2|Bacteria,2NPFM@2323|unclassified Bacteria	2|Bacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.191,2.1.1.264	ko:K06969,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
XH1_k127_1455911_2	583355.Caka_1804	1.011e-93	315.0	COG1092@1|root,COG1092@2|Bacteria,46UGW@74201|Verrucomicrobia,3K77P@414999|Opitutae	414999|Opitutae	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
XH1_k127_147251_4	891968.Anamo_0977	0.0002274	44.0	COG0683@1|root,COG0683@2|Bacteria,3TAJA@508458|Synergistetes	508458|Synergistetes	E	PFAM Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
XH1_k127_147251_0	592015.HMPREF1705_00886	5.475e-131	424.0	COG0559@1|root,COG0559@2|Bacteria,3TACI@508458|Synergistetes	508458|Synergistetes	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
XH1_k127_147251_1	592015.HMPREF1705_00885	2.182e-122	405.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,3TAPS@508458|Synergistetes	508458|Synergistetes	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
XH1_k127_147251_2	592015.HMPREF1705_00885	3.904e-91	308.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,3TAPS@508458|Synergistetes	508458|Synergistetes	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
XH1_k127_147251_3	1121468.AUBR01000023_gene2753	2.359e-58	209.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,42EMQ@68295|Thermoanaerobacterales	186801|Clostridia	E	ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
XH1_k127_1515990_2	1121342.AUCO01000027_gene1267	1.279e-52	201.0	COG1775@1|root,COG1775@2|Bacteria,1TS7H@1239|Firmicutes,2493U@186801|Clostridia,36H7V@31979|Clostridiaceae	186801|Clostridia	E	dehydratase	hgdA	-	1.3.7.8,4.2.1.157	ko:K04113,ko:K20025	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
XH1_k127_1515990_0	926569.ANT_17740	2.555e-84	294.0	COG2172@1|root,COG2524@1|root,COG2172@2|Bacteria,COG2524@2|Bacteria,2G9GZ@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
XH1_k127_1515990_4	706587.Desti_2742	1.421e-27	115.0	COG4109@1|root,COG4109@2|Bacteria,1N96M@1224|Proteobacteria,42V82@68525|delta/epsilon subdivisions,2WS7X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
XH1_k127_1515990_1	1167006.UWK_02682	9.328e-55	203.0	COG5616@1|root,COG5616@2|Bacteria,1P0ZV@1224|Proteobacteria	1224|Proteobacteria	S	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
XH1_k127_1515990_3	1121918.ARWE01000001_gene1797	4.23e-39	163.0	COG1404@1|root,COG1404@2|Bacteria,1QYWU@1224|Proteobacteria,42VXP@68525|delta/epsilon subdivisions,2X7PK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1515990_6	1499967.BAYZ01000167_gene6732	4.92e-19	100.0	2DRYY@1|root,33DRD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1515990_5	1379698.RBG1_1C00001G0584	1.402e-19	99.0	COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.4.24.40	ko:K01406,ko:K14274,ko:K20276,ko:K21449	ko00040,ko01503,ko02024,map00040,map01503,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL
XH1_k127_1518707_1	1121405.dsmv_3116	1.436e-95	316.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2WK5J@28221|Deltaproteobacteria,2MHV0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
XH1_k127_1518707_0	1336243.JAEA01000006_gene329	2.928e-223	707.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria,1JX4A@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Peptidase family M41	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
XH1_k127_1518707_2	439235.Dalk_4702	1.133e-79	272.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,2MHKB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
XH1_k127_1537973_2	56780.SYN_01628	1.166e-87	291.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2MR6S@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
XH1_k127_1537973_1	56780.SYN_01627	9.381e-151	486.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,2MRH5@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
XH1_k127_1537973_0	56780.SYN_02923	4.416e-242	774.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2MQ67@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
XH1_k127_1539537_1	56780.SYN_01071	2.407e-59	209.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PYA@68525|delta/epsilon subdivisions,2WKM5@28221|Deltaproteobacteria,2MQB0@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
XH1_k127_1539537_2	56780.SYN_01072	1.119e-52	192.0	COG0425@1|root,COG0425@2|Bacteria,1N08X@1224|Proteobacteria,42RUG@68525|delta/epsilon subdivisions,2WNNK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	yedF	-	-	-	-	-	-	-	-	-	-	-	DrsE,TusA
XH1_k127_1539537_3	56780.SYN_01183	1.026e-12	77.0	COG0822@1|root,COG0822@2|Bacteria	2|Bacteria	C	iron-sulfur transferase activity	-	-	-	ko:K04488,ko:K15790	-	-	-	-	ko00000	-	-	-	NifU_N
XH1_k127_1539537_0	1232428.CAVO010000014_gene757	1.321e-61	222.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4H217@909932|Negativicutes	909932|Negativicutes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
XH1_k127_1542650_15	378806.STAUR_5589	1.362e-20	105.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria,2YYVN@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
XH1_k127_1542650_3	338966.Ppro_1795	4.717e-106	365.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2WJE3@28221|Deltaproteobacteria,43UIB@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
XH1_k127_1542650_11	706587.Desti_2578	1.967e-36	147.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
XH1_k127_1542650_12	1121405.dsmv_3498	5.37e-32	134.0	2AIMV@1|root,31947@2|Bacteria,1Q1RW@1224|Proteobacteria,42U9F@68525|delta/epsilon subdivisions,2WQ95@28221|Deltaproteobacteria,2MKIY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
XH1_k127_1542650_7	429009.Adeg_0208	7.105e-66	240.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,42IEE@68295|Thermoanaerobacterales	186801|Clostridia	J	tRNA methyl transferase	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
XH1_k127_1542650_1	443144.GM21_3060	1.161e-111	376.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,43SBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
XH1_k127_1542650_6	290397.Adeh_2370	5.002e-69	242.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
XH1_k127_1542650_2	1121918.ARWE01000001_gene1223	6.192e-111	372.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,43U1Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
XH1_k127_1542650_16	439235.Dalk_4409	7.417e-14	77.0	2BHAV@1|root,32BCF@2|Bacteria,1NDPS@1224|Proteobacteria,42SQW@68525|delta/epsilon subdivisions,2WSCF@28221|Deltaproteobacteria,2MKA5@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1542650_8	426117.M446_5335	7.236e-58	209.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2TQJ9@28211|Alphaproteobacteria,1JS0W@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM beta-lactamase domain protein	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	-	-	-	-	-	-	-	-	-	-	Lactamase_B
XH1_k127_1542650_0	1125863.JAFN01000001_gene2828	7.298e-127	421.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43AW1@68525|delta/epsilon subdivisions,2X6A7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_1542650_13	1408422.JHYF01000004_gene1665	3.45e-25	122.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,36E1T@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GGDEF,HD,PAS,Response_reg
XH1_k127_1542650_4	56780.SYN_00104	2.205e-102	352.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MQKP@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
XH1_k127_1542650_18	316067.Geob_1620	1.047e-09	66.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K16191,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.6.1.3	-	-	Big_3_2,Calx-beta,OmpA
XH1_k127_1542650_19	1121896.JMLU01000041_gene557	5.548e-06	51.0	2CG1Y@1|root,31EK1@2|Bacteria,4NUTU@976|Bacteroidetes,1IJMJ@117743|Flavobacteriia,2P0RY@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
XH1_k127_1542650_9	555088.DealDRAFT_1548	3.694e-53	197.0	COG1073@1|root,COG1073@2|Bacteria,1UXYN@1239|Firmicutes,24DU6@186801|Clostridia,42KKD@68298|Syntrophomonadaceae	186801|Clostridia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
XH1_k127_1542650_10	641491.DND132_0473	2.117e-43	166.0	COG1648@1|root,COG1648@2|Bacteria,1RB3H@1224|Proteobacteria,42QT2@68525|delta/epsilon subdivisions,2WN1F@28221|Deltaproteobacteria,2MBSA@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	TIGRFAM siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
XH1_k127_1542650_14	338963.Pcar_3065	6.6e-22	107.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43SCE@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
XH1_k127_1542650_5	882.DVU_1461	4.569e-88	304.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2M7UJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
XH1_k127_1549298_3	1286171.EAL2_c06740	4.011e-122	405.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
XH1_k127_1549298_0	1230343.CANP01000023_gene1516	0.0	1295.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1JCJW@118969|Legionellales	118969|Legionellales	V	AcrB/AcrD/AcrF family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
XH1_k127_1549298_2	314345.SPV1_09403	8.553e-125	410.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrE	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
XH1_k127_1549298_1	439235.Dalk_1296	1.531e-233	737.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42NSP@68525|delta/epsilon subdivisions,2WMAD@28221|Deltaproteobacteria,2MHRF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase N terminal	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
XH1_k127_1549298_4	526222.Desal_0253	7.575e-42	162.0	COG2334@1|root,COG2334@2|Bacteria,1RBUF@1224|Proteobacteria,42R0R@68525|delta/epsilon subdivisions,2WMR4@28221|Deltaproteobacteria,2M9YB@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Aminoglycoside phosphotransferase	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
XH1_k127_1580539_3	269799.Gmet_0947	8.768e-24	104.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,42RID@68525|delta/epsilon subdivisions,2WN9N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase U62 modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
XH1_k127_1580539_0	1125863.JAFN01000001_gene2270	0.0	1101.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
XH1_k127_1580539_1	667014.Thein_0768	2.203e-95	329.0	COG1364@1|root,COG1364@2|Bacteria,2GGSA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
XH1_k127_1580539_2	1121451.DESAM_20789	2.892e-43	165.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,42UR3@68525|delta/epsilon subdivisions,2WQQQ@28221|Deltaproteobacteria,2M7TS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
XH1_k127_1594554_2	269799.Gmet_0053	1.146e-60	226.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,43TZR@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
XH1_k127_1594554_1	1122164.JHWF01000003_gene2136	8.289e-93	316.0	COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,1RPHS@1236|Gammaproteobacteria,1JCWT@118969|Legionellales	118969|Legionellales	I	Fatty acid desaturase	-	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
XH1_k127_1594554_0	309807.SRU_2375	5.034e-184	590.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,1FK09@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
XH1_k127_1598670_5	1121918.ARWE01000001_gene917	2.098e-22	97.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42PEN@68525|delta/epsilon subdivisions,2WJ9F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
XH1_k127_1598670_1	1304888.ATWF01000002_gene194	3.104e-143	459.0	COG0559@1|root,COG0559@2|Bacteria,2GF7N@200930|Deferribacteres	200930|Deferribacteres	P	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
XH1_k127_1598670_0	1121405.dsmv_0755	1.228e-175	559.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42M11@68525|delta/epsilon subdivisions,2WK66@28221|Deltaproteobacteria,2MI46@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
XH1_k127_1598670_2	1121405.dsmv_0756	1.563e-108	387.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2WJ48@28221|Deltaproteobacteria,2MITM@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
XH1_k127_1598670_3	1122132.AQYH01000007_gene1919	9.469e-67	235.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,4BDGN@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
XH1_k127_1598670_4	443144.GM21_1430	5.464e-51	183.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,42QR5@68525|delta/epsilon subdivisions,2WMSR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Lipocalin family protein	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
XH1_k127_1625205_4	644282.Deba_2305	1.14e-08	63.0	COG3144@1|root,COG3144@2|Bacteria	2|Bacteria	N	bacterial-type flagellum assembly	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
XH1_k127_1625205_2	596152.DesU5LDRAFT_1255	2.109e-38	152.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,42U4T@68525|delta/epsilon subdivisions,2WQ5B@28221|Deltaproteobacteria,2MBHG@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
XH1_k127_1625205_0	941449.dsx2_2060	5.985e-133	440.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42NGP@68525|delta/epsilon subdivisions,2WIZN@28221|Deltaproteobacteria,2M84P@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
XH1_k127_1625205_1	644282.Deba_2308	9.006e-92	308.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2WIQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
XH1_k127_1625205_3	644282.Deba_1620	4.451e-27	120.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42Q7D@68525|delta/epsilon subdivisions,2WKIT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
XH1_k127_1625205_5	639282.DEFDS_1718	1.898e-05	52.0	COG1360@1|root,COG1360@2|Bacteria,2GEMA@200930|Deferribacteres	200930|Deferribacteres	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
XH1_k127_1639192_0	1218084.BBJK01000038_gene3593	1.436e-109	364.0	28ID9@1|root,2Z8FI@2|Bacteria,1PD20@1224|Proteobacteria,2VP91@28216|Betaproteobacteria,1K406@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1639192_2	338963.Pcar_1967	2.667e-52	189.0	COG2258@1|root,COG2258@2|Bacteria,1RE9T@1224|Proteobacteria,42RPN@68525|delta/epsilon subdivisions,2WNWZ@28221|Deltaproteobacteria,43UP1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM MOSC domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
XH1_k127_1639192_3	1121396.KB892916_gene74	7.202e-45	177.0	2CM5J@1|root,33NXS@2|Bacteria,1NHWC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1639192_5	945713.IALB_0051	1.004e-27	121.0	2C945@1|root,32W5M@2|Bacteria	2|Bacteria	-	-	-	-	5.4.4.1	ko:K01865	ko00627,ko01120,map00627,map01120	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
XH1_k127_1639192_1	96561.Dole_2681	9.534e-54	193.0	COG3613@1|root,COG3613@2|Bacteria,1N451@1224|Proteobacteria,430HN@68525|delta/epsilon subdivisions,2WVQY@28221|Deltaproteobacteria,2MNRH@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
XH1_k127_1721720_1	472759.Nhal_2304	6.671e-32	127.0	2E46S@1|root,32Z2Q@2|Bacteria,1N7X1@1224|Proteobacteria,1SEK8@1236|Gammaproteobacteria,1WZB0@135613|Chromatiales	135613|Chromatiales	S	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1721720_2	330214.NIDE1072	1.141e-14	75.0	2DP6Q@1|root,330SE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1721720_0	1232437.KL662047_gene5148	1.127e-148	489.0	COG4775@1|root,COG4775@2|Bacteria,1R75N@1224|Proteobacteria,42MIG@68525|delta/epsilon subdivisions,2WMI0@28221|Deltaproteobacteria,2MIJA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
XH1_k127_1763847_3	311424.DhcVS_811	3.631e-103	349.0	COG1541@1|root,COG1541@2|Bacteria,2G695@200795|Chloroflexi,34CY3@301297|Dehalococcoidia	301297|Dehalococcoidia	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
XH1_k127_1763847_1	1123386.AUIW01000020_gene1580	1.322e-109	363.0	COG0410@1|root,COG0410@2|Bacteria,1WIEV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type branched-chain amino acid transport systems ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
XH1_k127_1763847_2	1304888.ATWF01000001_gene1076	2.987e-107	358.0	COG4177@1|root,COG4177@2|Bacteria,2GF0U@200930|Deferribacteres	200930|Deferribacteres	P	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
XH1_k127_1763847_5	1196031.ALEG01000046_gene4503	4.437e-81	279.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HEZ3@91061|Bacilli,1ZQ8V@1386|Bacillus	91061|Bacilli	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
XH1_k127_1763847_0	869210.Marky_1306	1.991e-173	578.0	COG1022@1|root,COG1022@2|Bacteria,1WIHH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
XH1_k127_1763847_4	926550.CLDAP_14320	2.73e-88	301.0	COG0411@1|root,COG0411@2|Bacteria,2G5VI@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
XH1_k127_1763847_6	706587.Desti_2889	2.691e-05	55.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,42ND9@68525|delta/epsilon subdivisions,2WK5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
XH1_k127_177053_10	1254432.SCE1572_34730	1.866e-28	122.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,FAD_binding_3,FAD_oxidored,HI0933_like,Lycopene_cycl
XH1_k127_177053_5	1121468.AUBR01000035_gene1382	9.686e-116	391.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42HW8@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_177053_1	865861.AZSU01000002_gene2792	4.532e-196	630.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,36FZW@31979|Clostridiaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
XH1_k127_177053_8	439235.Dalk_3791	2.192e-58	217.0	2DNNY@1|root,32YCS@2|Bacteria,1NDIA@1224|Proteobacteria,4314H@68525|delta/epsilon subdivisions,2WX5B@28221|Deltaproteobacteria,2MNZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_177053_7	7739.XP_002603155.1	1.854e-60	219.0	COG1028@1|root,KOG1201@2759|Eukaryota,38DUA@33154|Opisthokonta,3B9V8@33208|Metazoa,3CS2U@33213|Bilateria,485XD@7711|Chordata	33208|Metazoa	Q	keratinocyte proliferation	SDR16C5	GO:0000122,GO:0000988,GO:0000989,GO:0001076,GO:0001191,GO:0001523,GO:0003674,GO:0003824,GO:0004745,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005789,GO:0005811,GO:0006066,GO:0006081,GO:0006355,GO:0006357,GO:0006629,GO:0006720,GO:0006721,GO:0006950,GO:0008134,GO:0008150,GO:0008152,GO:0008283,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010604,GO:0010605,GO:0010629,GO:0010638,GO:0010639,GO:0010817,GO:0012505,GO:0016020,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0017053,GO:0019219,GO:0019222,GO:0031056,GO:0031057,GO:0031058,GO:0031063,GO:0031065,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031399,GO:0031400,GO:0031401,GO:0031984,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032991,GO:0033043,GO:0033044,GO:0033555,GO:0033613,GO:0034308,GO:0034754,GO:0035065,GO:0035067,GO:0042175,GO:0042445,GO:0042572,GO:0042574,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043616,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045892,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050673,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0055114,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090311,GO:0090312,GO:0098827,GO:0140110,GO:1901615,GO:1901983,GO:1901984,GO:1902275,GO:1902679,GO:1903506,GO:1903507,GO:1905268,GO:1905269,GO:2000112,GO:2000113,GO:2000756,GO:2000757,GO:2001141,GO:2001251,GO:2001252	1.1.1.105	ko:K15734	ko00830,map00830	-	R02124	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
XH1_k127_177053_3	880073.Calab_3204	5.405e-149	491.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
XH1_k127_177053_9	439235.Dalk_3870	3.985e-45	174.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,Fer4_7
XH1_k127_177053_2	439235.Dalk_1136	4.674e-154	504.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WUG9@28221|Deltaproteobacteria,2MMW2@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_177053_11	575593.HMPREF0491_01309	1.188e-14	81.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia,27I5Q@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cupin domain	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
XH1_k127_177053_0	644282.Deba_1534	1.256e-282	872.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42N6X@68525|delta/epsilon subdivisions,2WJIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
XH1_k127_177053_6	644282.Deba_1535	1.066e-88	299.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
XH1_k127_177053_4	706587.Desti_2061	5.146e-128	415.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_1775190_0	909663.KI867150_gene430	3.639e-134	439.0	COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,42MTS@68525|delta/epsilon subdivisions,2WJ50@28221|Deltaproteobacteria,2MQWX@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
XH1_k127_1775190_2	1304874.JAFY01000005_gene1602	6.594e-27	110.0	COG1278@1|root,COG1278@2|Bacteria,3TBIM@508458|Synergistetes	508458|Synergistetes	K	PFAM Cold-shock protein DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
XH1_k127_1775190_1	880073.Calab_0273	1.529e-126	421.0	COG2195@1|root,COG2195@2|Bacteria,2NP2Y@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
XH1_k127_1803240_0	926550.CLDAP_37780	3.23e-99	331.0	COG0475@1|root,COG0490@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria	2|Bacteria	P	domain protein	MA20_07375	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
XH1_k127_1803240_1	1121405.dsmv_0551	1.219e-31	137.0	COG2911@1|root,COG2911@2|Bacteria,1PQTA@1224|Proteobacteria,42PYT@68525|delta/epsilon subdivisions,2WIZ6@28221|Deltaproteobacteria,2MJ1Q@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
XH1_k127_1811986_1	96561.Dole_1604	4.211e-120	391.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	acyl-coa dehydrogenase	caiA	GO:0003674,GO:0003824,GO:0006066,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0016627,GO:0034308,GO:0034309,GO:0044281,GO:0044283,GO:0046165,GO:0052890,GO:0055114,GO:0071270,GO:0071271,GO:0071704,GO:1901576,GO:1901615,GO:1901617	1.3.8.13	ko:K08297	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_1811986_2	96561.Dole_1603	2.943e-109	359.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_1811986_3	96561.Dole_1602	1.808e-66	229.0	COG1545@1|root,COG1545@2|Bacteria,1RB09@1224|Proteobacteria,437V5@68525|delta/epsilon subdivisions,2X34N@28221|Deltaproteobacteria,2MNPW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
XH1_k127_1811986_0	96561.Dole_1601	1.076e-207	651.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,42ZT9@68525|delta/epsilon subdivisions,2WUUI@28221|Deltaproteobacteria,2MNC0@213118|Desulfobacterales	28221|Deltaproteobacteria	H	acetyl-coa acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C
XH1_k127_1811986_4	439235.Dalk_3100	0.0008996	43.0	COG0789@1|root,COG0789@2|Bacteria,1N7M7@1224|Proteobacteria,42WAT@68525|delta/epsilon subdivisions,2WRPH@28221|Deltaproteobacteria,2MMFX@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM regulatory protein MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
XH1_k127_1841583_2	596151.DesfrDRAFT_3544	2.37e-07	64.0	COG3209@1|root,COG3386@1|root,COG3209@2|Bacteria,COG3386@2|Bacteria,1MVV1@1224|Proteobacteria,43AER@68525|delta/epsilon subdivisions,2X5UG@28221|Deltaproteobacteria,2MGZZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,NHL,RHS_repeat
XH1_k127_1841583_1	1198114.AciX9_2489	8.009e-18	98.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	wcoG	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3,PKD
XH1_k127_1841583_0	318167.Sfri_1362	3.7e-38	147.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,1S5V4@1236|Gammaproteobacteria,2QBZ0@267890|Shewanellaceae	1236|Gammaproteobacteria	L	SMART HNH nuclease	yajD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HNH
XH1_k127_189350_0	1353528.DT23_17780	9.175e-35	145.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_189350_2	358681.BBR47_25800	5.827e-15	83.0	COG1309@1|root,COG1309@2|Bacteria,1V2I9@1239|Firmicutes,4HU2M@91061|Bacilli	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_189350_1	96561.Dole_2768	8.367e-24	112.0	2F1H5@1|root,33UHN@2|Bacteria,1NUUT@1224|Proteobacteria,42ZR9@68525|delta/epsilon subdivisions,2WUUD@28221|Deltaproteobacteria,2MN8Q@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1898511_2	1288826.MSNKSG1_13422	2.498e-31	132.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,464WP@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
XH1_k127_1898511_1	439235.Dalk_0514	1.2e-106	355.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,43AEV@68525|delta/epsilon subdivisions,2WKWE@28221|Deltaproteobacteria,2MJ82@213118|Desulfobacterales	68525|delta/epsilon subdivisions	S	PFAM 2-nitropropane dioxygenase NPD	-	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
XH1_k127_1898511_0	1202962.KB907184_gene242	2.171e-116	386.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RRA4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
XH1_k127_1961302_11	760142.Hipma_1458	1.899e-08	57.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2WKIR@28221|Deltaproteobacteria,2M6RX@213113|Desulfurellales	28221|Deltaproteobacteria	J	tRNA (Guanine-1)-methyltransferase	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_4,tRNA_m1G_MT
XH1_k127_1961302_8	443143.GM18_0672	1.256e-24	111.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,42TGI@68525|delta/epsilon subdivisions,2WQJU@28221|Deltaproteobacteria,43VFS@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
XH1_k127_1961302_7	909663.KI867150_gene967	4.955e-27	111.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MQIW@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
XH1_k127_1961302_10	537013.CLOSTMETH_02434	5.437e-21	95.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3WJSQ@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
XH1_k127_1961302_2	1198452.Jab_2c07800	4.312e-95	322.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2VIC1@28216|Betaproteobacteria,47563@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	transport system, periplasmic component	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
XH1_k127_1961302_0	338963.Pcar_0087	0.0	1180.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,43SBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	ABC transporter	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
XH1_k127_1961302_12	1158338.JNLJ01000001_gene942	8.916e-08	63.0	COG0760@1|root,COG0760@2|Bacteria,2G5GE@200783|Aquificae	200783|Aquificae	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3
XH1_k127_1961302_1	1232410.KI421420_gene3182	1.015e-237	775.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,43SCA@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TRCF	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
XH1_k127_1961302_6	1118054.CAGW01000082_gene2990	5.208e-40	164.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,26S70@186822|Paenibacillaceae	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
XH1_k127_1961302_5	357808.RoseRS_0537	6.043e-45	175.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
XH1_k127_1961302_9	1121920.AUAU01000030_gene2713	6.918e-23	102.0	2E6X5@1|root,331GM@2|Bacteria,3Y5N8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1961302_4	338963.Pcar_0012	7.91e-51	196.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PGR@68525|delta/epsilon subdivisions,2WJ4K@28221|Deltaproteobacteria,43VKS@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Metal-dependent phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
XH1_k127_1961302_3	944564.HMPREF9200_0277	5.216e-78	265.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,4H240@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
XH1_k127_1962570_1	644282.Deba_1051	1.278e-139	449.0	COG2368@1|root,COG2368@2|Bacteria	2|Bacteria	Q	4-hydroxyphenylacetate	-	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
XH1_k127_1962570_0	1304885.AUEY01000003_gene482	3.987e-145	469.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,42PQ6@68525|delta/epsilon subdivisions,2WJHR@28221|Deltaproteobacteria,2MJ66@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
XH1_k127_1962570_2	1304885.AUEY01000003_gene481	6.015e-52	188.0	COG1309@1|root,COG1309@2|Bacteria,1RCC8@1224|Proteobacteria,42R6Y@68525|delta/epsilon subdivisions,2WN1T@28221|Deltaproteobacteria,2MJPC@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_1980105_10	649638.Trad_2422	3.569e-42	162.0	COG1047@1|root,COG1047@2|Bacteria,1WI40@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
XH1_k127_1980105_5	1167006.UWK_01424	1.702e-128	426.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MI9P@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
XH1_k127_1980105_11	580332.Slit_0816	1.349e-21	103.0	COG3090@1|root,COG3090@2|Bacteria,1PJMD@1224|Proteobacteria,2VYB1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
XH1_k127_1980105_7	880073.Calab_1130	2.369e-66	241.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
XH1_k127_1980105_9	1163617.SCD_n01357	3.499e-46	180.0	COG5660@1|root,32WII@2|Bacteria,1R3ME@1224|Proteobacteria	1224|Proteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
XH1_k127_1980105_4	635013.TherJR_0012	5.484e-133	434.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,260T8@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
XH1_k127_1980105_2	706587.Desti_3801	7.603e-172	549.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MRBK@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_1980105_1	1131269.AQVV01000026_gene129	2.56e-193	639.0	COG0749@1|root,COG0749@2|Bacteria	2|Bacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
XH1_k127_1980105_8	269799.Gmet_0988	4.374e-50	182.0	COG1051@1|root,COG1051@2|Bacteria,1QUM0@1224|Proteobacteria,42SY6@68525|delta/epsilon subdivisions,2WP3N@28221|Deltaproteobacteria,43UZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
XH1_k127_1980105_12	289376.THEYE_A0747	1.542e-08	67.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
XH1_k127_1980105_3	96561.Dole_2226	5.729e-157	508.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2WJ7P@28221|Deltaproteobacteria,2MIXW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminopeptidase I zinc metalloprotease (M18)	apeA	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
XH1_k127_1980105_6	944481.JAFP01000001_gene244	1.463e-111	393.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2WJ81@28221|Deltaproteobacteria,2M6C9@213113|Desulfurellales	28221|Deltaproteobacteria	O	Elongator protein 3, MiaB family, Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
XH1_k127_1980105_0	56780.SYN_01708	2.21e-250	783.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2MQ9M@213462|Syntrophobacterales	28221|Deltaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
XH1_k127_2013452_0	706587.Desti_3278	4.991e-207	653.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42NEV@68525|delta/epsilon subdivisions,2WJD0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
XH1_k127_2013452_2	583355.Caka_1521	4.034e-24	114.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2358,DUF4440,SnoaL_2
XH1_k127_2013452_1	56780.SYN_01675	1.026e-76	263.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WJX5@28221|Deltaproteobacteria,2MQHE@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Cyclopropane-fatty-acyl-phospholipid synthase	cfa1	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	iAF987.Gmet_2187	CMAS
XH1_k127_2058413_0	439235.Dalk_4895	1.42e-146	475.0	COG1775@1|root,COG1775@2|Bacteria,1NT47@1224|Proteobacteria,42Z5X@68525|delta/epsilon subdivisions,2WTU0@28221|Deltaproteobacteria,2MMMH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
XH1_k127_2058413_1	96561.Dole_2771	3.98e-102	338.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42S61@68525|delta/epsilon subdivisions,2X5SR@28221|Deltaproteobacteria,2MPFW@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
XH1_k127_2061529_1	646529.Desaci_0410	2.753e-108	372.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia	186801|Clostridia	P	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
XH1_k127_2061529_0	243231.GSU1272	7.757e-140	456.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,43TM6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
XH1_k127_2061529_2	1121472.AQWN01000003_gene1403	6.163e-58	205.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,260AV@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
XH1_k127_2075300_5	96561.Dole_0040	0.0007442	43.0	COG0318@1|root,COG1143@1|root,COG0318@2|Bacteria,COG1143@2|Bacteria,1MWSD@1224|Proteobacteria,42Q72@68525|delta/epsilon subdivisions,2WM9N@28221|Deltaproteobacteria,2MJN1@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_2075300_0	96561.Dole_0112	3.407e-162	526.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,42Q72@68525|delta/epsilon subdivisions,2WM9N@28221|Deltaproteobacteria,2MJN1@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_2075300_1	1232437.KL662061_gene4127	6.439e-78	266.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42UW6@68525|delta/epsilon subdivisions,2WQ4A@28221|Deltaproteobacteria,2MIV9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
XH1_k127_2075300_3	748449.Halha_0146	1.212e-41	170.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia	186801|Clostridia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
XH1_k127_2075300_2	706587.Desti_5610	6.179e-42	161.0	COG1309@1|root,COG1309@2|Bacteria,1MV2V@1224|Proteobacteria,42NW6@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
XH1_k127_2075300_4	56780.SYN_00898	6.48e-22	102.0	COG3816@1|root,COG3816@2|Bacteria,1Q2AK@1224|Proteobacteria,437X9@68525|delta/epsilon subdivisions,2X372@28221|Deltaproteobacteria,2MS8V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1285)	-	-	-	ko:K09986	-	-	-	-	ko00000	-	-	-	DUF1285
XH1_k127_2108328_0	56780.SYN_02770	2.77e-118	386.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2MREZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Inorganic H+ pyrophosphatase	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
XH1_k127_2108328_1	644282.Deba_0774	2.98e-103	349.0	COG3875@1|root,COG3875@2|Bacteria,1R79Y@1224|Proteobacteria,42PGD@68525|delta/epsilon subdivisions,2WMB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
XH1_k127_2108328_2	1265505.ATUG01000001_gene3216	1.282e-19	90.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,2MJS3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
XH1_k127_2122049_2	404589.Anae109_1952	2.184e-22	100.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,43BPS@68525|delta/epsilon subdivisions,2X710@28221|Deltaproteobacteria,2YU4V@29|Myxococcales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
XH1_k127_2122049_0	1150474.JQJI01000007_gene234	4.919e-119	398.0	COG2204@1|root,COG2204@2|Bacteria,2GCJQ@200918|Thermotogae	2|Bacteria	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flgR	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_2122049_1	1121430.JMLG01000013_gene1872	7.39e-24	103.0	COG0477@1|root,COG0477@2|Bacteria,1UNMW@1239|Firmicutes,25ECT@186801|Clostridia,2607G@186807|Peptococcaceae	186801|Clostridia	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
XH1_k127_214293_0	1307759.JOMJ01000003_gene1214	9.543e-108	353.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,2M7VZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
XH1_k127_214293_2	574087.Acear_0105	2.707e-88	314.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,3WBGS@53433|Halanaerobiales	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
XH1_k127_214293_1	574087.Acear_0104	1.512e-94	321.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,3WBAM@53433|Halanaerobiales	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
XH1_k127_214293_3	511051.CSE_05990	3.453e-74	258.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
XH1_k127_214293_4	1123504.JQKD01000010_gene2535	3.471e-49	177.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,4AA1C@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
XH1_k127_2150800_0	96561.Dole_0041	4.967e-183	585.0	COG1960@1|root,COG1960@2|Bacteria,1R59X@1224|Proteobacteria,42P22@68525|delta/epsilon subdivisions,2WKQN@28221|Deltaproteobacteria,2MJCR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_2150800_1	439235.Dalk_3835	2.677e-110	368.0	COG1960@1|root,COG1960@2|Bacteria,1R7Q4@1224|Proteobacteria,42PIJ@68525|delta/epsilon subdivisions,2WJNP@28221|Deltaproteobacteria,2MIMZ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
XH1_k127_2150800_2	96561.Dole_0168	6.336e-54	194.0	COG1024@1|root,COG1024@2|Bacteria,1RJ10@1224|Proteobacteria,42YA2@68525|delta/epsilon subdivisions,2WUKV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_2190264_9	215803.DB30_2245	3.712e-07	59.0	28S5K@1|root,2ZEH5@2|Bacteria,1PW2U@1224|Proteobacteria,434UQ@68525|delta/epsilon subdivisions,2WZ5T@28221|Deltaproteobacteria,2Z1DY@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
XH1_k127_2190264_2	1121403.AUCV01000021_gene3556	3.992e-182	578.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2MI0G@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
XH1_k127_2190264_0	335543.Sfum_3301	2.657e-238	754.0	COG0119@1|root,COG0119@2|Bacteria,1R8DM@1224|Proteobacteria,42PDN@68525|delta/epsilon subdivisions,2WKIJ@28221|Deltaproteobacteria,2MQ4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Pyruvate carboxyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like,dCache_1
XH1_k127_2190264_8	398767.Glov_1623	3.616e-18	95.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	lysM	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	LysM
XH1_k127_2190264_1	1121403.AUCV01000001_gene807	1.28e-219	710.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2MI7X@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
XH1_k127_2190264_4	338963.Pcar_1041	6.423e-130	428.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,43SAP@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
XH1_k127_2190264_5	387631.Asulf_00583	1.079e-83	286.0	COG1032@1|root,arCOG01363@2157|Archaea,2XU5X@28890|Euryarchaeota,2461R@183980|Archaeoglobi	183980|Archaeoglobi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
XH1_k127_2190264_7	177437.HRM2_00570	5.166e-31	126.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,42T7R@68525|delta/epsilon subdivisions,2WPDU@28221|Deltaproteobacteria,2MK9K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
XH1_k127_2190264_3	335543.Sfum_2401	2.2e-131	446.0	COG0784@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg,dCache_1
XH1_k127_2190264_6	118163.Ple7327_4048	6.48e-71	254.0	COG5542@1|root,COG5542@2|Bacteria,1G3SR@1117|Cyanobacteria,3VNF5@52604|Pleurocapsales	1117|Cyanobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
XH1_k127_2205683_1	909663.KI867150_gene531	2.036e-196	621.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P8Q@68525|delta/epsilon subdivisions,2WK2B@28221|Deltaproteobacteria,2MQ4U@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K11384	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_2205683_2	909663.KI867150_gene530	5.197e-195	625.0	COG5002@1|root,COG5002@2|Bacteria,1R6WE@1224|Proteobacteria,42P99@68525|delta/epsilon subdivisions,2WK5E@28221|Deltaproteobacteria,2MQ9Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K11383	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8
XH1_k127_2205683_0	706587.Desti_1867	3.471e-255	799.0	COG2060@1|root,COG2060@2|Bacteria,1MV1K@1224|Proteobacteria,42NCD@68525|delta/epsilon subdivisions,2WJ03@28221|Deltaproteobacteria,2MQ3T@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
XH1_k127_2209355_1	717231.Flexsi_1172	1.194e-94	314.0	COG0148@1|root,COG0148@2|Bacteria,2GEVS@200930|Deferribacteres	200930|Deferribacteres	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
XH1_k127_2209355_0	96561.Dole_2187	3.979e-173	550.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2MI9F@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
XH1_k127_2214957_0	243231.GSU0579	2.673e-125	416.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria,43UB3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	glycyl-tRNA aminoacylation	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
XH1_k127_2214957_1	1121405.dsmv_3461	8.782e-114	386.0	COG0232@1|root,COG0232@2|Bacteria,1R6QQ@1224|Proteobacteria,42M0H@68525|delta/epsilon subdivisions,2WJ33@28221|Deltaproteobacteria,2MHN1@213118|Desulfobacterales	28221|Deltaproteobacteria	F	SMART metal-dependent phosphohydrolase HD region	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
XH1_k127_2214957_2	370438.PTH_1606	2.023e-11	65.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
XH1_k127_2225872_6	589865.DaAHT2_1722	9.644e-115	381.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2WIWG@28221|Deltaproteobacteria,2MI0U@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
XH1_k127_2225872_16	1120971.AUCA01000011_gene2951	1.02e-52	199.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H9VG@91061|Bacilli,278CU@186823|Alicyclobacillaceae	91061|Bacilli	N	SRP54-type protein, GTPase domain	flhF	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
XH1_k127_2225872_11	690850.Desaf_0122	1.581e-71	254.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42PF7@68525|delta/epsilon subdivisions,2WJB5@28221|Deltaproteobacteria,2M9FM@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
XH1_k127_2225872_10	1131269.AQVV01000001_gene1328	5.798e-76	262.0	COG1191@1|root,COG1191@2|Bacteria	2|Bacteria	K	sigma factor activity	fliA	-	-	ko:K02405,ko:K03093	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
XH1_k127_2225872_15	1121406.JAEX01000002_gene1029	1.417e-54	194.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,42RF8@68525|delta/epsilon subdivisions,2WNSP@28221|Deltaproteobacteria,2MBHU@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
XH1_k127_2225872_12	1121406.JAEX01000006_gene2245	8.868e-61	233.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WKB3@28221|Deltaproteobacteria,2M8UC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
XH1_k127_2225872_17	1125863.JAFN01000001_gene714	1.651e-48	184.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WQQK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
XH1_k127_2225872_7	1121439.dsat_0942	3.642e-94	317.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QJT@68525|delta/epsilon subdivisions,2WJ1S@28221|Deltaproteobacteria,2M8MF@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
XH1_k127_2225872_19	909663.KI867150_gene1952	4.406e-29	120.0	COG0745@1|root,COG0745@2|Bacteria,1RIN6@1224|Proteobacteria,42T2W@68525|delta/epsilon subdivisions,2WPU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
XH1_k127_2225872_5	1121430.JMLG01000019_gene1656	5.693e-129	427.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,260IP@186807|Peptococcaceae	186801|Clostridia	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
XH1_k127_2225872_2	234267.Acid_5892	3.279e-195	625.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
XH1_k127_2225872_14	880072.Desac_2335	2.706e-56	205.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,2MQKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
XH1_k127_2225872_9	338966.Ppro_3282	8.538e-81	285.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,43U0H@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
XH1_k127_2225872_21	290397.Adeh_3640	6.842e-19	92.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2Z2X2@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
XH1_k127_2225872_4	56780.SYN_02713	1.785e-159	514.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2MRG9@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_2225872_3	1232410.KI421415_gene3124	4.213e-192	625.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43SDF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PAS domain	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
XH1_k127_2225872_13	522772.Dacet_2771	1.509e-59	216.0	COG0774@1|root,COG0774@2|Bacteria,2GF3Y@200930|Deferribacteres	200930|Deferribacteres	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
XH1_k127_2225872_23	404589.Anae109_0948	2.612e-10	64.0	28S5K@1|root,2ZEH5@2|Bacteria,1NI42@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
XH1_k127_2225872_24	1121413.JMKT01000008_gene1252	2.433e-09	64.0	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42SCW@68525|delta/epsilon subdivisions,2WPNX@28221|Deltaproteobacteria,2MDHW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
XH1_k127_2225872_25	644282.Deba_2665	8.686e-07	56.0	2ENBB@1|root,32JZD@2|Bacteria,1NN3C@1224|Proteobacteria,42XM1@68525|delta/epsilon subdivisions,2WTC3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2225872_22	706587.Desti_3710	1.62e-15	82.0	COG0711@1|root,COG0711@2|Bacteria,1QR15@1224|Proteobacteria,43EXC@68525|delta/epsilon subdivisions,2X2GB@28221|Deltaproteobacteria,2MSFA@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ATP synthase B/B' CF(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
XH1_k127_2225872_20	667014.Thein_1330	7.9e-20	97.0	COG0711@1|root,COG0711@2|Bacteria,2GHRB@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
XH1_k127_2225872_18	1232410.KI421422_gene2046	2.497e-33	136.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,42U68@68525|delta/epsilon subdivisions,2WQJS@28221|Deltaproteobacteria,43SQK@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
XH1_k127_2225872_1	706587.Desti_3707	5.476e-238	744.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2MRD2@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
XH1_k127_2225872_8	706587.Desti_3706	2.265e-83	287.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2WJ6I@28221|Deltaproteobacteria,2MQDF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
XH1_k127_2225872_0	316067.Geob_0447	3.174e-241	751.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,43TRP@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
XH1_k127_2234809_4	1121920.AUAU01000007_gene559	3.286e-18	90.0	COG0784@1|root,COG1100@1|root,COG3852@1|root,COG0784@2|Bacteria,COG1100@2|Bacteria,COG3852@2|Bacteria,3Y9EH@57723|Acidobacteria	57723|Acidobacteria	T	Ras family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9,Ras,Response_reg
XH1_k127_2234809_2	1121918.ARWE01000001_gene1548	2.494e-23	109.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
XH1_k127_2234809_3	365659.smi_0092	1.492e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,1V4S4@1239|Firmicutes,4HH0U@91061|Bacilli,2TNU6@28037|Streptococcus mitis	91061|Bacilli	K	Transcriptional regulatory protein, C terminal	saeR	GO:0008150,GO:0010468,GO:0019222,GO:0050789,GO:0060255,GO:0065007	-	ko:K10682	ko02020,map02020	M00468	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
XH1_k127_2234809_5	1232410.KI421424_gene1656	1.708e-10	67.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,43UR0@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Universal stress protein	usp-2	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
XH1_k127_2234809_1	502025.Hoch_5592	3.129e-37	149.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2WMK3@28221|Deltaproteobacteria,2YVG8@29|Myxococcales	28221|Deltaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
XH1_k127_2234809_0	439235.Dalk_3407	1.63e-130	426.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WJ0U@28221|Deltaproteobacteria,2MI24@213118|Desulfobacterales	28221|Deltaproteobacteria	E	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
XH1_k127_2243412_2	686340.Metal_1236	1.803e-15	89.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_6,Laminin_G_3,Malectin,NPCBM
XH1_k127_2243412_0	96561.Dole_1916	8.603e-93	316.0	COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,42N0D@68525|delta/epsilon subdivisions,2WK3S@28221|Deltaproteobacteria,2MII2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
XH1_k127_2243412_1	96561.Dole_0665	7.043e-81	277.0	COG1024@1|root,COG1024@2|Bacteria,1RIVB@1224|Proteobacteria,42ZKD@68525|delta/epsilon subdivisions,2WUVX@28221|Deltaproteobacteria,2MNDG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_2265927_1	439235.Dalk_4685	2.663e-152	493.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria	1224|Proteobacteria	C	PFAM CoA-binding domain protein	MA20_15065	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
XH1_k127_2265927_3	56780.SYN_00095	4.399e-41	159.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
XH1_k127_2265927_0	56780.SYN_02703	8.435e-292	916.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Methionine synthase B12-binding module cap domain protein	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
XH1_k127_2265927_5	443143.GM18_0688	5.368e-26	113.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,43UYU@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
XH1_k127_2265927_2	56780.SYN_01815	1.511e-70	245.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2MRUQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
XH1_k127_2265927_4	525146.Ddes_1388	3.88e-31	125.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,42TU6@68525|delta/epsilon subdivisions,2WPZ1@28221|Deltaproteobacteria,2MBWV@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
XH1_k127_2282984_5	671143.DAMO_1652	0.0004688	46.0	COG2825@1|root,COG2825@2|Bacteria,2NQ6C@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
XH1_k127_2282984_1	1125863.JAFN01000001_gene3410	2.25e-92	314.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
XH1_k127_2282984_3	637389.Acaty_c0836	4.406e-87	294.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,2NBS7@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
XH1_k127_2282984_0	1232410.KI421414_gene2842	5.234e-93	315.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
XH1_k127_2282984_4	290397.Adeh_2625	1.331e-72	261.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
XH1_k127_2282984_2	56780.SYN_01564	1.233e-91	314.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria,2MQ69@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
XH1_k127_2290315_8	1206720.BAFQ01000150_gene3957	8.545e-05	51.0	COG1540@1|root,COG1540@2|Bacteria,2H5Y7@201174|Actinobacteria,4FVMS@85025|Nocardiaceae	201174|Actinobacteria	S	5-oxoprolinase (ATP-hydrolyzing) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2290315_4	909663.KI867150_gene804	4.322e-32	129.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WNC2@28221|Deltaproteobacteria,2MRPV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
XH1_k127_2290315_2	909663.KI867150_gene805	2.232e-48	183.0	COG1014@1|root,COG1014@2|Bacteria,1R92Y@1224|Proteobacteria,42QJI@68525|delta/epsilon subdivisions,2WMFZ@28221|Deltaproteobacteria,2MQJG@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
XH1_k127_2290315_1	706587.Desti_3039	6.255e-106	355.0	COG1013@1|root,COG1013@2|Bacteria,1N0HY@1224|Proteobacteria,42MTM@68525|delta/epsilon subdivisions,2WJS6@28221|Deltaproteobacteria,2MQAS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
XH1_k127_2290315_0	644282.Deba_2361	6.392e-139	450.0	COG0674@1|root,COG0674@2|Bacteria,1MWCI@1224|Proteobacteria,42NJY@68525|delta/epsilon subdivisions,2WIW3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
XH1_k127_2290315_7	97138.C820_00560	1.18e-18	87.0	COG1143@1|root,COG1143@2|Bacteria,1UHZA@1239|Firmicutes,24QVY@186801|Clostridia,36UN5@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7
XH1_k127_2290315_3	926569.ANT_27010	1.49e-34	137.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
XH1_k127_2290315_5	909663.KI867150_gene2715	7.505e-31	125.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,42VE3@68525|delta/epsilon subdivisions,2WR9Q@28221|Deltaproteobacteria,2MS6W@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
XH1_k127_2290315_6	56780.SYN_00029	7.308e-25	107.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2MRYF@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
XH1_k127_2291078_8	1121405.dsmv_0466	2.233e-09	64.0	COG4970@1|root,COG4970@2|Bacteria,1NAVW@1224|Proteobacteria,42V4H@68525|delta/epsilon subdivisions,2WRE8@28221|Deltaproteobacteria,2MM4W@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
XH1_k127_2291078_10	1304275.C41B8_02827	0.0009133	46.0	COG4967@1|root,COG4967@2|Bacteria,1R1MP@1224|Proteobacteria,1T55P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II secretion system (T2SS), protein I	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
XH1_k127_2291078_7	439235.Dalk_5153	1.434e-09	67.0	COG2165@1|root,COG2165@2|Bacteria,1R09J@1224|Proteobacteria,43CSN@68525|delta/epsilon subdivisions,2X80B@28221|Deltaproteobacteria,2MPMU@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
XH1_k127_2291078_3	909663.KI867149_gene3410	3.322e-31	136.0	COG3156@1|root,COG3156@2|Bacteria,1Q1GD@1224|Proteobacteria,4378U@68525|delta/epsilon subdivisions,2X2BV@28221|Deltaproteobacteria,2MSDA@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
XH1_k127_2291078_4	96561.Dole_1037	5.753e-28	129.0	COG4972@1|root,COG4972@2|Bacteria,1MYIB@1224|Proteobacteria,42SIX@68525|delta/epsilon subdivisions,2WP1G@28221|Deltaproteobacteria,2MKAU@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Fimbrial assembly family protein	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,PilM_2,PilN,T2SSL
XH1_k127_2291078_6	96561.Dole_1038	1.683e-12	76.0	COG3149@1|root,COG3149@2|Bacteria,1NEZ3@1224|Proteobacteria,42WMP@68525|delta/epsilon subdivisions,2WR67@28221|Deltaproteobacteria,2MKKX@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein M	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
XH1_k127_2291078_9	439235.Dalk_5149	2.618e-05	56.0	2DRH1@1|root,33BQ8@2|Bacteria,1NM8D@1224|Proteobacteria,42XND@68525|delta/epsilon subdivisions,2WSKN@28221|Deltaproteobacteria,2MM85@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	gspN	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
XH1_k127_2291078_0	572546.Arcpr_1617	1.658e-36	147.0	COG2236@1|root,arCOG00040@2157|Archaea,2XYCC@28890|Euryarchaeota,247HC@183980|Archaeoglobi	183980|Archaeoglobi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
XH1_k127_2291078_1	1121918.ARWE01000001_gene2959	2.896e-36	158.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42T0Q@68525|delta/epsilon subdivisions,2WUA0@28221|Deltaproteobacteria,43SZX@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF_2,GGDEF,Response_reg
XH1_k127_2291078_2	909663.KI867150_gene1751	9.016e-36	150.0	COG0637@1|root,COG0637@2|Bacteria,1QTT8@1224|Proteobacteria,42RX7@68525|delta/epsilon subdivisions,2WNPY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.5	ko:K20881	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
XH1_k127_2291078_5	717605.Theco_1357	6.208e-15	87.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,26QDE@186822|Paenibacillaceae	91061|Bacilli	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
XH1_k127_2298422_1	644282.Deba_0581	3.374e-52	186.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
XH1_k127_2298422_0	401526.TcarDRAFT_1976	5.537e-197	628.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4H1XW@909932|Negativicutes	909932|Negativicutes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
XH1_k127_2298422_2	589924.Ferp_0598	4.19e-23	104.0	COG0560@1|root,arCOG01158@2157|Archaea,2XT0C@28890|Euryarchaeota,2462F@183980|Archaeoglobi	183980|Archaeoglobi	E	phosphoserine phosphatase SerB	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
XH1_k127_2308604_1	1049564.TevJSym_ba00170	2.266e-23	101.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1J513@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
XH1_k127_2308604_0	706587.Desti_3975	7.24e-64	223.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,2MRJU@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
XH1_k127_2342448_8	1232410.KI421415_gene3082	1.635e-30	123.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
XH1_k127_2342448_5	644282.Deba_3193	3.106e-58	211.0	COG1309@1|root,COG1309@2|Bacteria,1R091@1224|Proteobacteria,430HV@68525|delta/epsilon subdivisions,2WVKP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
XH1_k127_2342448_6	439235.Dalk_1848	2.464e-46	173.0	COG1454@1|root,COG1454@2|Bacteria,1NCF7@1224|Proteobacteria,42VM0@68525|delta/epsilon subdivisions,2WS5T@28221|Deltaproteobacteria,2MNUI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
XH1_k127_2342448_3	644282.Deba_3195	2.316e-113	368.0	COG4739@1|root,COG4739@2|Bacteria,1NF16@1224|Proteobacteria,42WQ4@68525|delta/epsilon subdivisions,2WR8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized protein containing a ferredoxin domain (DUF2148)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2148,FeS
XH1_k127_2342448_4	644282.Deba_3196	2.3e-91	304.0	COG4739@1|root,COG4739@2|Bacteria	2|Bacteria	S	Uncharacterized protein containing a ferredoxin domain (DUF2148)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2148
XH1_k127_2342448_0	644282.Deba_3197	3.519e-245	771.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,42PNB@68525|delta/epsilon subdivisions,2WKT7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_2342448_2	644282.Deba_3198	5.285e-177	563.0	COG1960@1|root,COG1960@2|Bacteria,1P7WH@1224|Proteobacteria,42QKR@68525|delta/epsilon subdivisions,2WM93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_2342448_1	644282.Deba_3199	3.607e-197	621.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42QX5@68525|delta/epsilon subdivisions,2WJVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bbsB	-	-	ko:K07550	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05587	RC00004,RC01428,RC02904	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
XH1_k127_2342448_7	644282.Deba_3242	4.775e-41	157.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42UM2@68525|delta/epsilon subdivisions,2WR61@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
XH1_k127_2374392_1	744872.Spica_0027	5.737e-186	604.0	COG0334@1|root,COG0334@2|Bacteria,2J5DD@203691|Spirochaetes	203691|Spirochaetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gluD	-	1.4.1.2,1.4.1.3	ko:K00260,ko:K00261	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
XH1_k127_2374392_2	941449.dsx2_3431	1.02e-182	578.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2M9RZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Cys Met metabolism	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
XH1_k127_2374392_3	316067.Geob_0985	3.819e-42	159.0	COG3467@1|root,COG3467@2|Bacteria,1N4RH@1224|Proteobacteria,42TKQ@68525|delta/epsilon subdivisions,2WQ06@28221|Deltaproteobacteria,43VAD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
XH1_k127_2374392_0	933262.AXAM01000004_gene2356	0.0	1220.0	COG0574@1|root,COG0745@1|root,COG0574@2|Bacteria,COG0745@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2MICZ@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,PPDK_N
XH1_k127_2377573_5	1122947.FR7_4429	4.912e-15	77.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4H2MX@909932|Negativicutes	909932|Negativicutes	E	cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
XH1_k127_2377573_2	96561.Dole_1919	5.229e-102	341.0	COG2159@1|root,COG2159@2|Bacteria,1Q4Y5@1224|Proteobacteria,4304H@68525|delta/epsilon subdivisions,2WVAR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
XH1_k127_2377573_1	383372.Rcas_0489	1.067e-186	604.0	COG0367@1|root,COG0367@2|Bacteria,2G7R3@200795|Chloroflexi,376WK@32061|Chloroflexia	32061|Chloroflexia	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
XH1_k127_2377573_0	596152.DesU5LDRAFT_3249	1.819e-187	597.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2MATC@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
XH1_k127_2377573_4	933262.AXAM01000040_gene1228	1.274e-46	175.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2MK8A@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
XH1_k127_2377573_3	1045009.AFXQ01000008_gene1834	1.753e-56	206.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,1W7IB@1268|Micrococcaceae	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
XH1_k127_2390928_6	314278.NB231_03015	2.017e-15	83.0	2C40F@1|root,33WUG@2|Bacteria,1NWBW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2390928_2	1304885.AUEY01000046_gene15	5.24e-134	437.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42MUK@68525|delta/epsilon subdivisions,2X5CN@28221|Deltaproteobacteria,2MJ17@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TOBE domain	potA	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
XH1_k127_2390928_4	1304885.AUEY01000046_gene16	1.243e-91	311.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,42PMI@68525|delta/epsilon subdivisions,2WN46@28221|Deltaproteobacteria,2MJXV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
XH1_k127_2390928_3	1304885.AUEY01000046_gene17	1.982e-103	347.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,42MIJ@68525|delta/epsilon subdivisions,2WJKS@28221|Deltaproteobacteria,2MKBN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	potC2	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
XH1_k127_2390928_1	1304885.AUEY01000046_gene18	5.86e-136	440.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,42M6K@68525|delta/epsilon subdivisions,2WKQC@28221|Deltaproteobacteria,2MK8H@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
XH1_k127_2390928_5	290315.Clim_2438	4.558e-16	85.0	2C395@1|root,346D6@2|Bacteria,1FFIU@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2390928_0	243231.GSU1533	2.021e-201	651.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,42N6G@68525|delta/epsilon subdivisions,2WJ4Q@28221|Deltaproteobacteria,43T50@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
XH1_k127_2400639_3	1125863.JAFN01000001_gene3406	4.49e-10	68.0	COG2905@1|root,COG2905@2|Bacteria,1R0B9@1224|Proteobacteria,43CTI@68525|delta/epsilon subdivisions,2X8MP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	cNMP_binding
XH1_k127_2400639_1	515635.Dtur_0574	1.37e-97	330.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	wecB	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
XH1_k127_2400639_0	338963.Pcar_0742	1.27e-185	596.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,43U5S@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
XH1_k127_2400639_2	335543.Sfum_1034	1.391e-63	226.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,2MR88@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
XH1_k127_2415098_1	180332.JTGN01000003_gene1909	3.755e-70	251.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
XH1_k127_2415098_0	404380.Gbem_0488	1.227e-142	461.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,43UBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
XH1_k127_2415098_2	398767.Glov_0672	1.162e-59	219.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
XH1_k127_2424167_0	177437.HRM2_35240	2.778e-148	489.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MHV4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
XH1_k127_2424167_2	56780.SYN_00550	4.025e-95	323.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2MQBR@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
XH1_k127_2424167_4	439235.Dalk_1235	4.762e-53	199.0	COG0491@1|root,COG0491@2|Bacteria,1RIF3@1224|Proteobacteria,42TFP@68525|delta/epsilon subdivisions,2WP7U@28221|Deltaproteobacteria,2MK3E@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
XH1_k127_2424167_5	706587.Desti_1647	6.358e-26	112.0	COG0745@1|root,COG0745@2|Bacteria,1N3R6@1224|Proteobacteria,42TU3@68525|delta/epsilon subdivisions,2WQ9W@28221|Deltaproteobacteria,2MSJP@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
XH1_k127_2424167_3	933262.AXAM01000058_gene3193	8.272e-63	222.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42PPP@68525|delta/epsilon subdivisions,2WJ0H@28221|Deltaproteobacteria,2MPVY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AMMECR1	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
XH1_k127_2424167_1	941449.dsx2_1486	1.344e-129	426.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria,2M994@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
XH1_k127_2424167_6	909663.KI867150_gene2231	6.605e-08	54.0	COG0454@1|root,COG0456@2|Bacteria,1R418@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
XH1_k127_2425511_0	667014.Thein_1424	2.343e-239	760.0	COG0466@1|root,COG0466@2|Bacteria,2GICM@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Found in ATP-dependent protease La (LON)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
XH1_k127_2425511_1	644966.Tmar_2245	3.174e-159	512.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3WCHX@538999|Clostridiales incertae sedis	186801|Clostridia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
XH1_k127_2425511_7	909663.KI867150_gene2113	2.972e-27	118.0	COG1522@1|root,COG1522@2|Bacteria,1RCY6@1224|Proteobacteria,42R2R@68525|delta/epsilon subdivisions,2WMSJ@28221|Deltaproteobacteria,2MQJE@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	transcriptional regulator, AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_AsnC-type
XH1_k127_2425511_4	370438.PTH_2728	1.333e-63	229.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,25ZYM@186807|Peptococcaceae	186801|Clostridia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
XH1_k127_2425511_5	589865.DaAHT2_0960	6.658e-48	186.0	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,42PMY@68525|delta/epsilon subdivisions,2WPU5@28221|Deltaproteobacteria,2MM4P@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
XH1_k127_2425511_6	118005.AWNK01000014_gene887	5.917e-36	147.0	COG2992@1|root,COG2992@2|Bacteria	2|Bacteria	S	amidase activity	bax	-	-	ko:K03796	-	-	-	-	ko00000	-	GH73	-	Glucosaminidase
XH1_k127_2425511_12	1121406.JAEX01000023_gene1471	2.373e-08	60.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42WTD@68525|delta/epsilon subdivisions,2WSRU@28221|Deltaproteobacteria,2MDF1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpZ	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
XH1_k127_2425511_3	398767.Glov_3142	4.405e-76	262.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NR9@68525|delta/epsilon subdivisions,2WKX1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
XH1_k127_2425511_8	1121413.JMKT01000008_gene1424	5.438e-26	111.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42VAI@68525|delta/epsilon subdivisions,2WRI4@28221|Deltaproteobacteria,2MCKI@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
XH1_k127_2425511_9	866895.HBHAL_4080	2.621e-19	89.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,4HNPJ@91061|Bacilli,3NFFB@45667|Halobacillus	91061|Bacilli	T	Carbon storage regulator homolog	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
XH1_k127_2425511_2	525897.Dbac_2403	4.002e-84	301.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2WMMT@28221|Deltaproteobacteria,2M8P7@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
XH1_k127_2425511_11	1131269.AQVV01000022_gene2233	1.737e-08	55.0	COG1706@1|root,COG1706@2|Bacteria	2|Bacteria	N	bacterial-type flagellum-dependent cell motility	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
XH1_k127_2435659_0	243231.GSU3408	7.068e-122	395.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42NZ7@68525|delta/epsilon subdivisions,2WKSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
XH1_k127_2435659_4	1254432.SCE1572_34875	0.0001358	49.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,cNMP_binding
XH1_k127_2435659_2	1304885.AUEY01000008_gene2105	2.21e-41	162.0	COG3071@1|root,COG3071@2|Bacteria,1NNBM@1224|Proteobacteria,42XVS@68525|delta/epsilon subdivisions,2WT7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_17,TPR_19
XH1_k127_2435659_1	706587.Desti_2766	3.516e-87	300.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MRB2@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
XH1_k127_2435659_3	335543.Sfum_0420	2.296e-09	62.0	COG0664@1|root,COG0664@2|Bacteria,1QZ42@1224|Proteobacteria,42XK7@68525|delta/epsilon subdivisions,2WSIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
XH1_k127_2462282_1	439235.Dalk_1739	8.374e-121	395.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,42ZTX@68525|delta/epsilon subdivisions,2WVID@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2224	ECH_1
XH1_k127_2462282_2	439235.Dalk_1738	2.106e-94	334.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,42N6F@68525|delta/epsilon subdivisions,2WKX7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM 2-nitropropane dioxygenase NPD	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
XH1_k127_2462282_0	439235.Dalk_1737	4.439e-234	734.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2MN80@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.34	ko:K00666,ko:K12508	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_2462282_3	439235.Dalk_1736	2.754e-88	299.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2MI75@213118|Desulfobacterales	1224|Proteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	paaF	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
XH1_k127_2469114_1	909663.KI867150_gene1436	2.916e-100	330.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
XH1_k127_2469114_6	536232.CLM_2990	8.236e-10	63.0	COG1436@1|root,COG1436@2|Bacteria,1VAX7@1239|Firmicutes,24MXC@186801|Clostridia,36JRX@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
XH1_k127_2469114_2	909663.KI867150_gene1434	2.686e-85	295.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	DUF2764,vATP-synt_AC39
XH1_k127_2469114_5	909663.KI867150_gene1433	1.531e-48	180.0	COG1390@1|root,COG1390@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
XH1_k127_2469114_3	909663.KI867150_gene1432	3.306e-77	262.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	-	ATP-synt_C
XH1_k127_2469114_0	909663.KI867150_gene1431	8.227e-228	729.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42UWC@68525|delta/epsilon subdivisions,2X5C3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM V-type ATPase 116 kDa	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
XH1_k127_2469114_7	1298865.H978DRAFT_3910	0.0001124	47.0	COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,1RPEP@1236|Gammaproteobacteria,46AC7@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	hydroxymethylglutaryl-CoA reductase	-	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
XH1_k127_2469114_4	368407.Memar_0267	7.739e-57	211.0	COG0247@1|root,arCOG00333@2157|Archaea,2Y487@28890|Euryarchaeota	28890|Euryarchaeota	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
XH1_k127_2482187_6	289376.THEYE_A0815	6.456e-25	111.0	COG1360@1|root,COG1360@2|Bacteria,3J0MN@40117|Nitrospirae	40117|Nitrospirae	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
XH1_k127_2482187_5	639282.DEFDS_1717	2.652e-32	132.0	COG1580@1|root,COG1580@2|Bacteria,2GFRS@200930|Deferribacteres	200930|Deferribacteres	N	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
XH1_k127_2482187_1	644282.Deba_2312	1.482e-105	351.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,42N2Y@68525|delta/epsilon subdivisions,2WIS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	flagellar motor switch protein FliM	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
XH1_k127_2482187_4	1121448.DGI_0887	4.15e-40	154.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,42TQB@68525|delta/epsilon subdivisions,2WQCQ@28221|Deltaproteobacteria,2MB3C@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	PFAM surface presentation of antigens (SPOA) protein	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
XH1_k127_2482187_8	1122212.AULO01000009_gene870	2.187e-09	64.0	COG3190@1|root,COG3190@2|Bacteria,1N79Z@1224|Proteobacteria,1SCKP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	flagellar	fliO	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
XH1_k127_2482187_2	589865.DaAHT2_1718	8.11e-83	282.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,42NDZ@68525|delta/epsilon subdivisions,2WKCN@28221|Deltaproteobacteria,2MHSW@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
XH1_k127_2482187_7	56780.SYN_02834	5.338e-23	105.0	COG1987@1|root,COG1987@2|Bacteria,1Q3RH@1224|Proteobacteria,43DVW@68525|delta/epsilon subdivisions,2X2FZ@28221|Deltaproteobacteria,2MSDF@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	Bacterial export proteins, family 3	-	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
XH1_k127_2482187_3	1379281.AVAG01000043_gene293	1.195e-40	164.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2WQ35@28221|Deltaproteobacteria,2MGD6@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
XH1_k127_2482187_9	1415630.U771_19605	0.0005362	51.0	28PJ2@1|root,2ZC8V@2|Bacteria,1RBEN@1224|Proteobacteria,1S375@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2482187_0	404380.Gbem_1753	7.87e-172	561.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43TPJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
XH1_k127_2496690_2	96561.Dole_1617	4.999e-60	215.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2MIK2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA-2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
XH1_k127_2496690_3	483219.LILAB_19350	1.36e-17	93.0	COG3031@1|root,COG3031@2|Bacteria,1RFDB@1224|Proteobacteria,42WP0@68525|delta/epsilon subdivisions,2X6P7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	General secretion pathway protein C	-	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
XH1_k127_2496690_0	439235.Dalk_5147	3.55e-85	301.0	COG3266@1|root,COG3267@1|root,COG3409@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,2MIMN@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Peptidoglycan-binding domain 1 protein	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
XH1_k127_2496690_4	1304284.L21TH_2410	2.083e-11	74.0	COG0457@1|root,COG0457@2|Bacteria,1UYZH@1239|Firmicutes,24BU9@186801|Clostridia,36F2E@31979|Clostridiaceae	186801|Clostridia	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
XH1_k127_2496690_1	1121405.dsmv_0458	2.835e-62	231.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2MIEH@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
XH1_k127_2509630_0	439235.Dalk_1136	3.428e-117	391.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WUG9@28221|Deltaproteobacteria,2MMW2@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_260765_6	56780.SYN_02764	6.516e-07	51.0	COG1853@1|root,COG1853@2|Bacteria,1QNV2@1224|Proteobacteria,42TD3@68525|delta/epsilon subdivisions,2WPRM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
XH1_k127_260765_2	177437.HRM2_08860	3.422e-179	579.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MHYV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase N terminal	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
XH1_k127_260765_5	1385935.N836_23005	8.242e-62	222.0	COG2267@1|root,COG2267@2|Bacteria,1G2EN@1117|Cyanobacteria,1H7RF@1150|Oscillatoriales	1117|Cyanobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
XH1_k127_260765_0	411901.BACCAC_00091	7.847e-230	722.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,2FPWZ@200643|Bacteroidia,4AP1W@815|Bacteroidaceae	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
XH1_k127_260765_3	243231.GSU1880	2.842e-171	544.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,43TWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
XH1_k127_260765_1	1125863.JAFN01000001_gene1104	1.51e-193	614.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
XH1_k127_260765_4	243231.GSU2091	4.33e-110	366.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,43UB6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
XH1_k127_2669211_2	1304885.AUEY01000021_gene3462	2.663e-204	643.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
XH1_k127_2669211_1	1121405.dsmv_0189	0.0	1021.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MI5@68525|delta/epsilon subdivisions,2WITQ@28221|Deltaproteobacteria,2MI9V@213118|Desulfobacterales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
XH1_k127_2669211_3	96561.Dole_0156	7.345e-164	526.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42M0D@68525|delta/epsilon subdivisions,2WK8T@28221|Deltaproteobacteria,2MJ65@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
XH1_k127_2669211_5	1121918.ARWE01000001_gene3124	4.068e-85	295.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WKPK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
XH1_k127_2669211_4	331678.Cphamn1_0208	1.21e-155	497.0	COG0502@1|root,COG0502@2|Bacteria,1FD7J@1090|Chlorobi	1090|Chlorobi	H	PFAM Radical SAM domain protein	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	-
XH1_k127_2669211_0	1121918.ARWE01000001_gene165	0.0	1219.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,42MZ4@68525|delta/epsilon subdivisions,2WJPB@28221|Deltaproteobacteria,43T5J@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
XH1_k127_2669211_7	177437.HRM2_01360	3.841e-52	188.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42SHQ@68525|delta/epsilon subdivisions,2WP9W@28221|Deltaproteobacteria,2MK3D@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
XH1_k127_2669211_8	555779.Dthio_PD3121	3.086e-30	123.0	COG0450@1|root,COG0450@2|Bacteria,1NBK9@1224|Proteobacteria,42VFJ@68525|delta/epsilon subdivisions,2WRB3@28221|Deltaproteobacteria,2MDBU@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
XH1_k127_2669211_6	177437.HRM2_32850	9.172e-85	282.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WNIG@28221|Deltaproteobacteria,2MJSH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	AhpC/TSA family	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
XH1_k127_2691447_0	941449.dsx2_0773	2.768e-167	536.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,43BFS@68525|delta/epsilon subdivisions,2WUH4@28221|Deltaproteobacteria,2MH6Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
XH1_k127_2691447_3	443143.GM18_1890	4.699e-19	91.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
XH1_k127_2691447_2	1499967.BAYZ01000069_gene1882	2.44e-90	303.0	COG0149@1|root,COG0149@2|Bacteria,2NP24@2323|unclassified Bacteria	2|Bacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
XH1_k127_2691447_1	330214.NIDE1106	4.912e-140	456.0	COG0126@1|root,COG0126@2|Bacteria,3J0DE@40117|Nitrospirae	40117|Nitrospirae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
XH1_k127_2711070_0	1297742.A176_06707	2.683e-69	245.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
XH1_k127_2711070_1	909663.KI867150_gene890	1.687e-21	102.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,2MRZD@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
XH1_k127_271160_0	879212.DespoDRAFT_00881	2.985e-118	388.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42QHF@68525|delta/epsilon subdivisions,2X5K9@28221|Deltaproteobacteria,2MIJM@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
XH1_k127_271160_1	1121396.KB892957_gene3226	1.479e-50	188.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42QHF@68525|delta/epsilon subdivisions,2X5K9@28221|Deltaproteobacteria,2MIJM@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
XH1_k127_2729991_1	903818.KI912269_gene423	3.48e-78	265.0	COG1149@1|root,COG1149@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_9,Flavodoxin_5
XH1_k127_2729991_3	439235.Dalk_4498	7.594e-56	212.0	COG1266@1|root,COG1266@2|Bacteria,1N67K@1224|Proteobacteria,42UUV@68525|delta/epsilon subdivisions,2WR6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
XH1_k127_2729991_2	439235.Dalk_4497	1.621e-77	269.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,42U8Q@68525|delta/epsilon subdivisions,2X5AX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
XH1_k127_2729991_0	883.DvMF_0822	5.93e-294	912.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2M885@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
XH1_k127_2737263_2	207954.MED92_10249	7.05e-44	168.0	COG0834@1|root,COG0834@2|Bacteria,1N076@1224|Proteobacteria,1SAEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
XH1_k127_2737263_3	1499967.BAYZ01000055_gene4869	3.971e-43	165.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_3,TetR_C_4,TetR_N
XH1_k127_2737263_0	56780.SYN_01461	5.06e-110	365.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria,2MSKN@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	HlyD family secretion protein	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
XH1_k127_2737263_1	909663.KI867150_gene2916	7.472e-75	259.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria,2MQXZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
XH1_k127_2793283_1	56780.SYN_01629	1.01e-243	766.0	COG0070@1|root,COG0493@1|root,COG1145@1|root,COG0070@2|Bacteria,COG0493@2|Bacteria,COG1145@2|Bacteria,1PBEZ@1224|Proteobacteria,42NFW@68525|delta/epsilon subdivisions,2WIQE@28221|Deltaproteobacteria,2MR5X@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	GXGXG motif	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,GXGXG,Pyr_redox_2,Pyr_redox_3,ThiF
XH1_k127_2793283_0	56780.SYN_01630	7.999e-298	933.0	COG0069@1|root,COG1145@1|root,COG0069@2|Bacteria,COG1145@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJ17@28221|Deltaproteobacteria,2MRAB@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S double cluster binding domain	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_16,Glu_synthase
XH1_k127_2793283_2	883.DvMF_2387	8.897e-147	473.0	COG0067@1|root,COG0067@2|Bacteria,1MW6C@1224|Proteobacteria,42MTE@68525|delta/epsilon subdivisions,2WJ9E@28221|Deltaproteobacteria,2MH95@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2793283_3	335543.Sfum_0570	9.001e-16	77.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MQVH@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
XH1_k127_2820172_3	667014.Thein_1583	4.374e-66	233.0	COG2203@1|root,COG2204@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG2206@2|Bacteria,2GIQV@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
XH1_k127_2820172_9	76114.ebA3993	3.914e-26	124.0	COG0515@1|root,COG0515@2|Bacteria,1R47Q@1224|Proteobacteria,2WGQS@28216|Betaproteobacteria,2KVBN@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
XH1_k127_2820172_4	868864.Dester_0001	1.866e-54	205.0	COG0438@1|root,COG0438@2|Bacteria,2G49S@200783|Aquificae	200783|Aquificae	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.87	ko:K00743	ko00601,map00601	-	R05978,R06169	-	ko00000,ko00001,ko01000,ko01003	-	GT6	-	Glyco_transf_4,Glycos_transf_1
XH1_k127_2820172_2	1121413.JMKT01000017_gene463	1.46e-94	316.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria,2MHBU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH1_k127_2820172_11	653045.Strvi_0225	1.196e-13	81.0	COG4641@1|root,COG4641@2|Bacteria,2H1Z7@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
XH1_k127_2820172_10	243090.RB2498	1.093e-18	96.0	COG2242@1|root,COG2242@2|Bacteria,2J0UY@203682|Planctomycetes	203682|Planctomycetes	H	TIGRFAM methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
XH1_k127_2820172_8	296591.Bpro_5441	1.522e-31	136.0	COG0500@1|root,COG2226@2|Bacteria,1N1HA@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
XH1_k127_2820172_0	177437.HRM2_18300	6.756e-101	343.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,43AFG@68525|delta/epsilon subdivisions,2WKA9@28221|Deltaproteobacteria,2MI8V@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
XH1_k127_2820172_5	1232437.KL662006_gene4451	1.775e-38	156.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,43AFG@68525|delta/epsilon subdivisions,2WKA9@28221|Deltaproteobacteria,2MHR2@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
XH1_k127_2820172_1	247634.GPB2148_756	6.324e-96	327.0	COG0535@1|root,COG0535@2|Bacteria,1NEM7@1224|Proteobacteria	1224|Proteobacteria	M	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
XH1_k127_2820172_7	572479.Hprae_1565	2.506e-34	140.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,3WBEI@53433|Halanaerobiales	186801|Clostridia	K	COGs COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains	-	-	-	ko:K03721	-	-	-	-	ko00000,ko03000	-	-	-	CBS,HTH_8,PAS,Sigma54_activat
XH1_k127_2849322_3	1192034.CAP_2334	7.405e-22	98.0	2EPPY@1|root,33HAH@2|Bacteria,1NHER@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2849322_2	443144.GM21_1217	1.178e-46	173.0	COG1716@1|root,COG1716@2|Bacteria,1NC3A@1224|Proteobacteria	1224|Proteobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
XH1_k127_2849322_0	330214.NIDE1987	2.224e-175	572.0	COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,3J13S@40117|Nitrospirae	40117|Nitrospirae	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
XH1_k127_2856411_0	580340.Tlie_0643	1.75e-153	497.0	COG0480@1|root,COG0480@2|Bacteria,3T9WH@508458|Synergistetes	508458|Synergistetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
XH1_k127_2856411_1	443143.GM18_0312	1.232e-81	280.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
XH1_k127_2869118_3	485915.Dret_0087	2.418e-25	111.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2M8IF@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Lytic transglycosylase catalytic	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
XH1_k127_2869118_2	1499967.BAYZ01000016_gene6535	5.316e-48	188.0	COG4447@1|root,COG4447@2|Bacteria,2NQ80@2323|unclassified Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
XH1_k127_2869118_5	697282.Mettu_3886	1.064e-08	67.0	COG1749@1|root,COG2319@1|root,COG2372@1|root,COG1749@2|Bacteria,COG2319@2|Bacteria,COG2372@2|Bacteria,1MWJA@1224|Proteobacteria,1S1AJ@1236|Gammaproteobacteria,1XF66@135618|Methylococcales	135618|Methylococcales	N	WD40 repeat, subgroup	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,WD40
XH1_k127_2869118_4	1304885.AUEY01000022_gene3402	1.616e-15	90.0	COG1388@1|root,COG1388@2|Bacteria,1R9WA@1224|Proteobacteria,42RAT@68525|delta/epsilon subdivisions,2WN3X@28221|Deltaproteobacteria,2MJI1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
XH1_k127_2869118_1	1265505.ATUG01000001_gene3881	2.881e-165	546.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
XH1_k127_2869118_0	1379281.AVAG01000065_gene1155	0.0	1064.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,2M9Q4@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
XH1_k127_2869664_1	56780.SYN_02101	7.88e-88	293.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42QR2@68525|delta/epsilon subdivisions,2WMS7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
XH1_k127_2869664_4	56780.SYN_02102	1.499e-34	135.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42UFU@68525|delta/epsilon subdivisions,2WQ4V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
XH1_k127_2869664_3	56780.SYN_02103	3.036e-50	188.0	COG0711@1|root,COG0711@2|Bacteria,1R6C0@1224|Proteobacteria,42T9H@68525|delta/epsilon subdivisions,2WPFT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
XH1_k127_2869664_0	56780.SYN_02104	2.385e-221	696.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2MRD2@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	-	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
XH1_k127_2869664_2	313624.NSP_4360	8.548e-71	247.0	COG0224@1|root,COG0224@2|Bacteria,1G1MJ@1117|Cyanobacteria	1117|Cyanobacteria	C	COG0224 F0F1-type ATP synthase gamma subunit	-	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
XH1_k127_290512_1	1034345.CAEM01000023_gene834	2.366e-57	207.0	COG0543@1|root,COG0543@2|Bacteria,2HXFY@201174|Actinobacteria,4CV8F@84998|Coriobacteriia	84998|Coriobacteriia	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
XH1_k127_290512_0	335543.Sfum_1766	2.272e-122	405.0	COG2896@1|root,COG2896@2|Bacteria,1MXMH@1224|Proteobacteria,42NTM@68525|delta/epsilon subdivisions,2WKIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
XH1_k127_290512_2	880073.Calab_2577	1.136e-49	201.0	COG2204@1|root,COG2208@1|root,COG2204@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CBS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE,dCache_1
XH1_k127_290512_3	55601.VANGNB10_cI1403c	8.956e-38	143.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1XSBD@135623|Vibrionales	135623|Vibrionales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
XH1_k127_2968063_5	1547445.LO80_07935	6.318e-54	192.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4600M@72273|Thiotrichales	72273|Thiotrichales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
XH1_k127_2968063_6	269799.Gmet_0028	1.467e-39	149.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,43V9Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
XH1_k127_2968063_4	237368.SCABRO_00764	3.974e-57	204.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
XH1_k127_2968063_3	439235.Dalk_1063	1.794e-66	236.0	2B1VX@1|root,31UC0@2|Bacteria,1NRD2@1224|Proteobacteria,42YTI@68525|delta/epsilon subdivisions,2WUNH@28221|Deltaproteobacteria,2MMH9@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2968063_0	439235.Dalk_1064	5.93e-152	487.0	COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,42Q04@68525|delta/epsilon subdivisions,2WKF7@28221|Deltaproteobacteria,2MK1D@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Transketolase, pyrimidine binding domain	tklB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
XH1_k127_2968063_2	439235.Dalk_1065	1.399e-109	361.0	COG3959@1|root,COG3959@2|Bacteria,1MWRX@1224|Proteobacteria,42P7U@68525|delta/epsilon subdivisions,2WKZQ@28221|Deltaproteobacteria,2MK06@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Dehydrogenase E1 component	tklA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
XH1_k127_2968063_1	439235.Dalk_2475	3.049e-129	425.0	COG2006@1|root,COG2006@2|Bacteria,1R9FE@1224|Proteobacteria,42QMT@68525|delta/epsilon subdivisions,2WKDC@28221|Deltaproteobacteria,2MJW3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
XH1_k127_2993982_1	439235.Dalk_3856	4.234e-98	332.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,2MJ60@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
XH1_k127_2993982_5	264732.Moth_2198	5.082e-41	155.0	COG1522@1|root,COG1522@2|Bacteria,1V6TK@1239|Firmicutes,24KE6@186801|Clostridia,42GS8@68295|Thermoanaerobacterales	186801|Clostridia	K	SMART Transcription regulator, AsnC-type	nirD	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
XH1_k127_2993982_9	331678.Cphamn1_2375	5.952e-13	76.0	2EBAA@1|root,335AW@2|Bacteria,1FESU@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2993982_8	517418.Ctha_1974	1.584e-16	87.0	2EBAA@1|root,335AW@2|Bacteria,1FF5M@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2993982_6	309798.COPRO5265_1272	8.536e-29	119.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,42GIZ@68295|Thermoanaerobacterales	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
XH1_k127_2993982_7	378806.STAUR_1855	1.316e-27	114.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,2YVQW@29|Myxococcales	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
XH1_k127_2993982_4	316067.Geob_0609	1.331e-44	177.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,43TVZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
XH1_k127_2993982_0	1123371.ATXH01000038_gene1353	1.433e-167	536.0	COG0014@1|root,COG0014@2|Bacteria,2GH1U@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
XH1_k127_2993982_2	269799.Gmet_3198	9.056e-91	311.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,43SXM@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
XH1_k127_2993982_3	1051632.TPY_0657	6.229e-54	194.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3WCE5@538999|Clostridiales incertae sedis	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
XH1_k127_3035259_3	234267.Acid_7514	6.548e-20	91.0	COG3696@1|root,COG3696@2|Bacteria,3Y3AQ@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
XH1_k127_3035259_0	1304885.AUEY01000052_gene1547	2.338e-96	329.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2MIM9@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
XH1_k127_3035259_1	1304885.AUEY01000052_gene1548	1.465e-94	326.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PZ3@68525|delta/epsilon subdivisions,2WJU4@28221|Deltaproteobacteria,2MIHB@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
XH1_k127_3035259_4	1249480.B649_11415	3.934e-07	57.0	2CCD9@1|root,32NJ2@2|Bacteria,1Q3UE@1224|Proteobacteria,42XU5@68525|delta/epsilon subdivisions,2YQSW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
XH1_k127_3035259_2	290315.Clim_2176	1.282e-43	160.0	COG0031@1|root,COG0031@2|Bacteria,1FD8M@1090|Chlorobi	1090|Chlorobi	H	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
XH1_k127_3046762_0	96561.Dole_1534	1.002e-101	338.0	COG0596@1|root,COG0596@2|Bacteria,1QTTM@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
XH1_k127_3046762_2	1121396.KB893081_gene1745	3.236e-43	169.0	28V7D@1|root,2ZHAI@2|Bacteria,1RA29@1224|Proteobacteria,42R9H@68525|delta/epsilon subdivisions,2WN1D@28221|Deltaproteobacteria,2MJN2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
XH1_k127_3046762_1	1047013.AQSP01000113_gene743	4.675e-45	170.0	COG3225@1|root,COG3225@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
XH1_k127_3077328_9	1304885.AUEY01000007_gene1340	2.143e-39	153.0	COG1309@1|root,COG1309@2|Bacteria,1MY9X@1224|Proteobacteria,43A5T@68525|delta/epsilon subdivisions,2X9YA@28221|Deltaproteobacteria,2MK3T@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_3077328_8	886293.Sinac_6848	1.805e-40	162.0	COG0451@1|root,COG0451@2|Bacteria,2J2KW@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
XH1_k127_3077328_10	96561.Dole_1325	3.387e-32	128.0	2AJQY@1|root,31ACW@2|Bacteria,1Q5CW@1224|Proteobacteria,4311R@68525|delta/epsilon subdivisions,2WWI4@28221|Deltaproteobacteria,2MP0K@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3077328_0	96561.Dole_1326	1.938e-250	783.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,42NVI@68525|delta/epsilon subdivisions,2WJTD@28221|Deltaproteobacteria,2MMNF@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
XH1_k127_3077328_1	439235.Dalk_3287	3.511e-142	462.0	COG1063@1|root,COG1063@2|Bacteria,1RB1A@1224|Proteobacteria,42QVR@68525|delta/epsilon subdivisions,2WMTW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
XH1_k127_3077328_2	56780.SYN_02762	3.444e-124	415.0	COG1624@1|root,COG4856@1|root,COG1624@2|Bacteria,COG4856@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
XH1_k127_3077328_11	311424.DhcVS_969	5.75e-19	89.0	COG0826@1|root,COG0826@2|Bacteria,2GAVB@200795|Chloroflexi,34DF3@301297|Dehalococcoidia	301297|Dehalococcoidia	O	peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3077328_3	1191523.MROS_0175	1.212e-117	404.0	COG1022@1|root,COG1022@2|Bacteria	2|Bacteria	I	Amp-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
XH1_k127_3077328_7	56780.SYN_00539	4.403e-41	158.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WPQ1@28221|Deltaproteobacteria,2MRTY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
XH1_k127_3077328_5	644282.Deba_1749	1.784e-67	243.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C2A@68525|delta/epsilon subdivisions,2X7CW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
XH1_k127_3077328_12	644282.Deba_1750	1.203e-18	90.0	COG0745@1|root,COG0745@2|Bacteria,1RINR@1224|Proteobacteria,42T1R@68525|delta/epsilon subdivisions,2WPHY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
XH1_k127_3077328_4	1123371.ATXH01000005_gene2038	8.929e-117	392.0	COG2204@1|root,COG2204@2|Bacteria,2GGZ6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_3077328_6	880072.Desac_2882	3.65e-61	219.0	COG2203@1|root,COG3829@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
XH1_k127_3084485_2	667014.Thein_0517	3.045e-36	139.0	COG0681@1|root,COG0681@2|Bacteria,2GH8B@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
XH1_k127_3084485_1	504728.K649_03425	6.491e-42	160.0	COG2065@1|root,COG2065@2|Bacteria,1WJWR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
XH1_k127_3084485_0	1232410.KI421413_gene593	1.734e-78	272.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,43S21@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
XH1_k127_3134496_1	96561.Dole_2772	2.355e-81	275.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42Z1Q@68525|delta/epsilon subdivisions,2WUFF@28221|Deltaproteobacteria,2MMV9@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
XH1_k127_3134496_4	96561.Dole_2773	2.236e-52	193.0	COG1614@1|root,COG1614@2|Bacteria,1PASY@1224|Proteobacteria,433D6@68525|delta/epsilon subdivisions,2WXEC@28221|Deltaproteobacteria,2MP32@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CO dehydrogenase/acetyl-CoA synthase complex beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhC
XH1_k127_3134496_2	96561.Dole_2777	1.636e-66	235.0	COG3640@1|root,COG3640@2|Bacteria,1MYT9@1224|Proteobacteria,430T9@68525|delta/epsilon subdivisions,2WVTW@28221|Deltaproteobacteria,2MNKY@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Anion-transporting ATPase	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	-
XH1_k127_3134496_7	1101192.KB910516_gene3768	0.0001693	51.0	COG1340@1|root,COG4249@1|root,COG1340@2|Bacteria,COG4249@2|Bacteria,1MUDG@1224|Proteobacteria,2TU22@28211|Alphaproteobacteria,1JT8B@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
XH1_k127_3134496_5	1040989.AWZU01000032_gene3433	8.439e-24	103.0	COG3360@1|root,COG3360@2|Bacteria,1PE74@1224|Proteobacteria,2UCH8@28211|Alphaproteobacteria,3K04J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
XH1_k127_3134496_6	323098.Nwi_2460	2.168e-16	81.0	COG3360@1|root,COG3360@2|Bacteria,1PE74@1224|Proteobacteria,2UCH8@28211|Alphaproteobacteria,3K04J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
XH1_k127_3134496_3	402881.Plav_1794	2.57e-61	221.0	COG1024@1|root,COG1024@2|Bacteria,1R3Q4@1224|Proteobacteria,2U3E5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
XH1_k127_3134496_0	1265505.ATUG01000002_gene2088	3.207e-98	342.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria,2MIWR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
XH1_k127_3142341_5	665571.STHERM_c01490	5.527e-146	473.0	COG0111@1|root,COG0111@2|Bacteria,2J6NN@203691|Spirochaetes	203691|Spirochaetes	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
XH1_k127_3142341_2	56780.SYN_00123	3.356e-177	570.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2MQZI@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
XH1_k127_3142341_4	879212.DespoDRAFT_02805	1.152e-148	482.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2MI7I@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
XH1_k127_3142341_16	439235.Dalk_0219	4.29e-11	66.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
XH1_k127_3142341_10	697281.Mahau_1084	1.512e-55	203.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
XH1_k127_3142341_14	556261.HMPREF0240_00555	1.63e-39	162.0	COG0407@1|root,COG0407@2|Bacteria,1URPV@1239|Firmicutes,24XIW@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
XH1_k127_3142341_7	96561.Dole_3232	1.906e-100	335.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,42P1A@68525|delta/epsilon subdivisions,2WM73@28221|Deltaproteobacteria,2MIVM@213118|Desulfobacterales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
XH1_k127_3142341_3	243231.GSU2241	8.082e-156	498.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,43TPG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NAD(P)H-binding	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
XH1_k127_3142341_12	1121918.ARWE01000001_gene2585	3.725e-41	160.0	COG1011@1|root,COG1011@2|Bacteria,1PHPQ@1224|Proteobacteria,42S23@68525|delta/epsilon subdivisions,2WNER@28221|Deltaproteobacteria,43SII@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
XH1_k127_3142341_6	640512.BC1003_2928	2.765e-133	434.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,1K2TQ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
XH1_k127_3142341_15	1191523.MROS_0743	7.635e-35	139.0	COG0632@1|root,COG0632@2|Bacteria	2|Bacteria	L	four-way junction helicase activity	ruvA	GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
XH1_k127_3142341_13	269799.Gmet_0744	2.499e-40	158.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,43US0@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
XH1_k127_3142341_8	1121405.dsmv_1370	2.409e-99	329.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2MIE0@213118|Desulfobacterales	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
XH1_k127_3142341_11	56780.SYN_02800	1.166e-44	171.0	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,42M1M@68525|delta/epsilon subdivisions,2X5M1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
XH1_k127_3142341_9	909663.KI867150_gene1438	6.73e-83	280.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,42VQ3@68525|delta/epsilon subdivisions,2WT1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
XH1_k127_3142341_0	909663.KI867150_gene1437	6.569e-256	796.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
XH1_k127_3142341_1	909663.KI867150_gene1436	3.593e-211	661.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
XH1_k127_3148550_0	1125863.JAFN01000001_gene2163	4.85e-261	814.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
XH1_k127_3148550_7	1125863.JAFN01000001_gene2162	5.141e-97	332.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
XH1_k127_3148550_9	926566.Terro_0893	2.013e-24	107.0	COG0736@1|root,COG0736@2|Bacteria,3Y590@57723|Acidobacteria,2JJPD@204432|Acidobacteriia	204432|Acidobacteriia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
XH1_k127_3148550_8	1131269.AQVV01000003_gene730	3.207e-26	114.0	COG0802@1|root,COG0802@2|Bacteria	2|Bacteria	S	tRNA threonylcarbamoyladenosine modification	yjeE	-	2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	TsaE
XH1_k127_3148550_4	243231.GSU1799	2.094e-159	513.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WIWZ@28221|Deltaproteobacteria,43U9Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM aspartate glutamate uridylate kinase	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
XH1_k127_3148550_2	639282.DEFDS_1179	1.51e-190	608.0	COG0119@1|root,COG0119@2|Bacteria,2GF1G@200930|Deferribacteres	200930|Deferribacteres	E	LeuA allosteric (dimerisation) domain	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
XH1_k127_3148550_6	243231.GSU2094	6.976e-111	366.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,43C4U@68525|delta/epsilon subdivisions,2WMNA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
XH1_k127_3148550_10	316067.Geob_0770	5.527e-18	87.0	2E47B@1|root,32Z37@2|Bacteria,1NC7T@1224|Proteobacteria,42VYF@68525|delta/epsilon subdivisions,2WRN2@28221|Deltaproteobacteria,43VKY@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3148550_1	290397.Adeh_0622	5.77e-213	675.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YTYC@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
XH1_k127_3148550_3	316067.Geob_3373	5.538e-160	511.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
XH1_k127_3148550_5	1278073.MYSTI_06379	2.206e-149	482.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
XH1_k127_316974_1	1163730.FFONT_0227	1.203e-98	336.0	COG1454@1|root,arCOG00984@2157|Archaea,2XQBU@28889|Crenarchaeota	28889|Crenarchaeota	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1,1.2.1.10	ko:K00001,ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00004,RC00050,RC00087,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
XH1_k127_316974_0	1163730.FFONT_0226	2.671e-115	383.0	COG2414@1|root,arCOG00706@2157|Archaea,2XQ6E@28889|Crenarchaeota	28889|Crenarchaeota	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
XH1_k127_317330_1	243231.GSU3404	6.211e-111	363.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
XH1_k127_317330_0	243231.GSU3405	2.911e-119	389.0	COG0765@1|root,COG0765@2|Bacteria,1MWF0@1224|Proteobacteria,42NEI@68525|delta/epsilon subdivisions,2WJP9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
XH1_k127_317330_2	1121396.KB893123_gene1103	5.515e-107	351.0	COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,42PQN@68525|delta/epsilon subdivisions,2WKV7@28221|Deltaproteobacteria,2MJFP@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
XH1_k127_317330_3	224324.aq_281	1.084e-12	76.0	COG1309@1|root,COG1309@2|Bacteria,2G57J@200783|Aquificae	200783|Aquificae	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_317330_4	7370.XP_005178329.1	2.393e-06	58.0	COG1960@1|root,KOG0139@2759|Eukaryota,38H6J@33154|Opisthokonta,3BC6X@33208|Metazoa,3CVK7@33213|Bilateria,41VCW@6656|Arthropoda,3SIYA@50557|Insecta,452NN@7147|Diptera	33208|Metazoa	E	flavin adenine dinucleotide binding. It is involved in the biological process described with oxidation-reduction process	ACADS	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_3216370_2	439235.Dalk_0611	6.559e-06	58.0	COG1413@1|root,COG1413@2|Bacteria,1NDC5@1224|Proteobacteria,42VM1@68525|delta/epsilon subdivisions,2WRE6@28221|Deltaproteobacteria,2MMBT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
XH1_k127_3216370_0	639282.DEFDS_1268	7.835e-89	301.0	COG0489@1|root,COG0489@2|Bacteria,2GEUR@200930|Deferribacteres	200930|Deferribacteres	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	ParA
XH1_k127_3216370_1	765912.Thimo_3543	4.188e-22	102.0	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,1S1DR@1236|Gammaproteobacteria,1WWIA@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
XH1_k127_321783_0	247490.KSU1_C1000	2.027e-136	460.0	COG1198@1|root,COG1198@2|Bacteria,2IY1F@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
XH1_k127_321783_4	1500897.JQNA01000002_gene100	9.504e-05	53.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,2VNIJ@28216|Betaproteobacteria,1K4RB@119060|Burkholderiaceae	28216|Betaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
XH1_k127_321783_2	378806.STAUR_7675	3.357e-83	286.0	COG1192@1|root,COG1192@2|Bacteria,1Q4ZN@1224|Proteobacteria,43082@68525|delta/epsilon subdivisions,2WV4J@28221|Deltaproteobacteria,2YYCR@29|Myxococcales	28221|Deltaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
XH1_k127_321783_1	269799.Gmet_1992	5.179e-108	359.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Q6R@68525|delta/epsilon subdivisions,2WJN4@28221|Deltaproteobacteria,43TK0@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_3221297_13	633131.TR2A62_1584	6.137e-46	176.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
XH1_k127_3221297_4	1121405.dsmv_2022	2.023e-109	361.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,42Q9R@68525|delta/epsilon subdivisions,2WKU4@28221|Deltaproteobacteria,2MIVX@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
XH1_k127_3221297_11	1121438.JNJA01000001_gene2094	2.378e-65	241.0	COG1355@1|root,COG1355@2|Bacteria,1N5H1@1224|Proteobacteria,42TIN@68525|delta/epsilon subdivisions,2WR24@28221|Deltaproteobacteria,2M9HE@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
XH1_k127_3221297_10	1499967.BAYZ01000185_gene4540	9.175e-70	244.0	COG0037@1|root,COG0037@2|Bacteria	2|Bacteria	D	tRNA processing	ttcA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	6.3.4.19	ko:K04075,ko:K14058	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
XH1_k127_3221297_3	1201293.AKXQ01000012_gene4039	1.525e-114	378.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RRA4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
XH1_k127_3221297_14	370438.PTH_2704	2.109e-18	98.0	COG0789@1|root,COG0789@2|Bacteria,1VMKZ@1239|Firmicutes,24W7J@186801|Clostridia,2636R@186807|Peptococcaceae	186801|Clostridia	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
XH1_k127_3221297_9	1304885.AUEY01000036_gene2241	5.298e-75	261.0	COG1024@1|root,COG1024@2|Bacteria,1RIVB@1224|Proteobacteria,42PMV@68525|delta/epsilon subdivisions,2WKCQ@28221|Deltaproteobacteria,2MHM8@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_3221297_1	1499967.BAYZ01000155_gene629	8.335e-153	491.0	COG0116@1|root,COG0116@2|Bacteria	2|Bacteria	L	23S rRNA (guanine(2445)-N(2))-methyltransferase activity	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
XH1_k127_3221297_6	1415166.NONO_c52270	2.964e-79	276.0	COG0451@1|root,COG0451@2|Bacteria,2GN90@201174|Actinobacteria,4G6AP@85025|Nocardiaceae	201174|Actinobacteria	GM	Male sterility protein	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_10
XH1_k127_3221297_5	1123401.JHYQ01000031_gene3379	9.204e-83	282.0	2CCV8@1|root,2Z7KX@2|Bacteria,1MY2J@1224|Proteobacteria,1S2KN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
XH1_k127_3221297_8	1304885.AUEY01000024_gene2729	5.703e-77	281.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42MBY@68525|delta/epsilon subdivisions,2WIR5@28221|Deltaproteobacteria,2MISX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K19954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
XH1_k127_3221297_15	382464.ABSI01000021_gene373	6.333e-17	83.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,2IURJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
XH1_k127_3221297_0	338969.Rfer_1964	5.009e-242	768.0	COG5322@1|root,COG5322@2|Bacteria,1R60X@1224|Proteobacteria,2W0QF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3221297_17	1211844.CBLM010000077_gene2490	1.186e-05	58.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,3VPEU@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
XH1_k127_3221297_2	357808.RoseRS_2761	2.094e-120	404.0	COG1020@1|root,COG1020@2|Bacteria,2G7PI@200795|Chloroflexi	200795|Chloroflexi	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
XH1_k127_3221297_16	309807.SRU_2684	9.759e-11	68.0	COG3937@1|root,COG3937@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
XH1_k127_3221297_7	439235.Dalk_1593	8.164e-78	273.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,42UGM@68525|delta/epsilon subdivisions,2WQR2@28221|Deltaproteobacteria,2MPGU@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
XH1_k127_3221297_12	1122197.ATWI01000016_gene2216	1.643e-58	214.0	COG1426@1|root,COG1426@2|Bacteria,1RIIX@1224|Proteobacteria,1S62E@1236|Gammaproteobacteria,46B8I@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3226884_0	1125863.JAFN01000001_gene150	2.126e-131	428.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,42NTY@68525|delta/epsilon subdivisions,2WK4F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
XH1_k127_3226884_1	1304885.AUEY01000085_gene2478	1.669e-119	399.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42MWE@68525|delta/epsilon subdivisions,2WKIZ@28221|Deltaproteobacteria,2MQ1J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
XH1_k127_3226884_2	1125863.JAFN01000001_gene148	4.13e-116	382.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,42PNU@68525|delta/epsilon subdivisions,2WM5D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
XH1_k127_3226884_3	371731.Rsw2DRAFT_1680	2.035e-64	237.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,1FAUV@1060|Rhodobacter	28211|Alphaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
XH1_k127_3230107_9	96561.Dole_1558	4.275e-12	70.0	COG0639@1|root,COG0639@2|Bacteria,1NWNG@1224|Proteobacteria,42ZUX@68525|delta/epsilon subdivisions,2WVAF@28221|Deltaproteobacteria,2MNHM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
XH1_k127_3230107_6	1131812.JQMS01000001_gene879	2.299e-121	400.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,1HYQ4@117743|Flavobacteriia,2NV4I@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143,HTH_11
XH1_k127_3230107_2	1304885.AUEY01000045_gene244	1.953e-163	528.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42NXM@68525|delta/epsilon subdivisions,2WJ2I@28221|Deltaproteobacteria,2MKRK@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
XH1_k127_3230107_5	536233.CLO_3149	4.283e-127	417.0	COG1018@1|root,COG1018@2|Bacteria,1TRG2@1239|Firmicutes,24CTI@186801|Clostridia,36EJ1@31979|Clostridiaceae	186801|Clostridia	C	Oxidoreductase FAD-binding domain	-	-	1.14.12.17	ko:K05916	ko05132,map05132	-	-	-	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
XH1_k127_3230107_3	56780.SYN_02671	1.616e-152	490.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,2MR0E@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Beta-eliminating lyase	degT	-	2.6.1.98	ko:K13017	ko00520,map00520	-	R10141	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
XH1_k127_3230107_8	338966.Ppro_1148	1.827e-23	102.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
XH1_k127_3230107_7	688269.Theth_1596	1.793e-32	131.0	COG2361@1|root,COG2361@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
XH1_k127_3230107_1	1121441.AUCX01000002_gene2762	6.908e-221	696.0	COG0110@1|root,COG0673@1|root,COG0110@2|Bacteria,COG0673@2|Bacteria,1MZV9@1224|Proteobacteria,42PR0@68525|delta/epsilon subdivisions,2WMBK@28221|Deltaproteobacteria,2M8E3@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,Hexapep,Hexapep_2
XH1_k127_3230107_0	56780.SYN_02675	1.698e-270	840.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria,2MQAP@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
XH1_k127_3230107_4	795359.TOPB45_0365	4.922e-138	452.0	COG1596@1|root,COG1596@2|Bacteria,2GI4R@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
XH1_k127_3231728_2	706587.Desti_1638	1.161e-76	261.0	COG1028@1|root,COG1545@1|root,COG3255@1|root,COG3425@1|root,COG1028@2|Bacteria,COG1545@2|Bacteria,COG3255@2|Bacteria,COG3425@2|Bacteria,1MXNQ@1224|Proteobacteria	1224|Proteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	MA20_27450	-	-	-	-	-	-	-	-	-	-	-	adh_short
XH1_k127_3231728_0	439235.Dalk_3190	5.807e-194	616.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42NW7@68525|delta/epsilon subdivisions,2WKQD@28221|Deltaproteobacteria,2MJ4I@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
XH1_k127_3231728_5	1120973.AQXL01000133_gene1710	3.841e-32	142.0	COG2030@1|root,COG2030@2|Bacteria,1VGYS@1239|Firmicutes,4HJK1@91061|Bacilli	91061|Bacilli	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
XH1_k127_3231728_3	1121422.AUMW01000009_gene3330	4.495e-44	164.0	COG2030@1|root,COG2030@2|Bacteria,1V8MB@1239|Firmicutes	1239|Firmicutes	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
XH1_k127_3231728_1	439235.Dalk_3191	4.412e-117	383.0	COG1028@1|root,COG1545@1|root,COG3255@1|root,COG3425@1|root,COG1028@2|Bacteria,COG1545@2|Bacteria,COG3255@2|Bacteria,COG3425@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria,2MHRA@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,MaoC_dehydrat_N,MaoC_dehydratas,OB_aCoA_assoc,SCP2,adh_short
XH1_k127_3231728_4	1487953.JMKF01000047_gene2136	1.248e-43	168.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
XH1_k127_3311626_2	439235.Dalk_4867	6.116e-60	215.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,2MI4X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM formate C-acetyltransferase glycine radical	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
XH1_k127_3311626_1	521045.Kole_0816	2.047e-70	244.0	COG0325@1|root,COG0325@2|Bacteria,2GCRN@200918|Thermotogae	200918|Thermotogae	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
XH1_k127_3311626_0	552811.Dehly_0408	1.946e-98	331.0	COG1693@1|root,COG1693@2|Bacteria,2GAMC@200795|Chloroflexi,34CRM@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Ribonuclease R winged-helix domain	-	-	-	ko:K09720	-	-	-	-	ko00000,ko03000	-	-	-	DUF128,HTH_12
XH1_k127_3311626_3	439235.Dalk_4867	1.348e-20	94.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,2MI4X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM formate C-acetyltransferase glycine radical	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
XH1_k127_3319386_2	443144.GM21_2716	1.134e-71	245.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RMH@68525|delta/epsilon subdivisions,2WNKC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Electron transfer flavoprotein alpha beta-subunit	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
XH1_k127_3319386_1	269799.Gmet_0684	7.069e-208	654.0	COG1145@1|root,COG2025@1|root,COG1145@2|Bacteria,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	iAF987.Gmet_2066	ETF,ETF_alpha,Fer4
XH1_k127_3319386_0	316067.Geob_1809	1.193e-285	891.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,43T69@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
XH1_k127_3319386_3	1341181.FLJC2902T_04210	1.358e-22	106.0	2AECJ@1|root,31473@2|Bacteria,4NZDM@976|Bacteroidetes,1ICQ6@117743|Flavobacteriia,2NU6A@237|Flavobacterium	976|Bacteroidetes	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
XH1_k127_3333953_0	1499967.BAYZ01000096_gene4310	7.097e-130	437.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HAMP,HTH_8,PAS,PAS_3,PAS_4,PAS_9,Response_reg,Sigma54_activat
XH1_k127_3333953_1	96561.Dole_1162	2.285e-89	304.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,42PBW@68525|delta/epsilon subdivisions,2WJV5@28221|Deltaproteobacteria,2MIXQ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
XH1_k127_3383266_4	1379281.AVAG01000042_gene822	0.0002488	47.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42WTD@68525|delta/epsilon subdivisions,2WSRU@28221|Deltaproteobacteria,2MDF1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpZ	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
XH1_k127_3383266_0	96561.Dole_0062	1.511e-146	473.0	COG0407@1|root,COG0407@2|Bacteria,1Q2RU@1224|Proteobacteria,42Q1G@68525|delta/epsilon subdivisions,2WJQU@28221|Deltaproteobacteria,2MIA3@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
XH1_k127_3383266_1	96561.Dole_0061	5.968e-45	170.0	COG5012@1|root,COG5012@2|Bacteria,1NETI@1224|Proteobacteria,42WMG@68525|delta/epsilon subdivisions,2WRJK@28221|Deltaproteobacteria,2MKYH@213118|Desulfobacterales	28221|Deltaproteobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding
XH1_k127_3383266_2	96561.Dole_2962	8.252e-30	127.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
XH1_k127_3383266_3	1268239.PALB_17370	7.976e-06	48.0	COG1075@1|root,COG1075@2|Bacteria,1NMH0@1224|Proteobacteria,1T4ZT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
XH1_k127_3390282_0	498761.HM1_0105	7.883e-251	784.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia	186801|Clostridia	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
XH1_k127_3390282_1	448385.sce3330	3.512e-79	277.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42Q5K@68525|delta/epsilon subdivisions,2X5HI@28221|Deltaproteobacteria,2Z35R@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
XH1_k127_3390282_2	1541960.KQ78_01395	3.073e-15	85.0	COG2804@1|root,COG2804@2|Bacteria,3WUB4@544448|Tenericutes	544448|Tenericutes	NU	Type II secretion system (T2SS), protein E, N-terminal domain	epsE	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
XH1_k127_3390282_3	587753.EY04_31435	8.896e-09	66.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	twitching motility protein	pilT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
XH1_k127_3407084_1	96561.Dole_1601	1.571e-174	552.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,42ZT9@68525|delta/epsilon subdivisions,2WUUI@28221|Deltaproteobacteria,2MNC0@213118|Desulfobacterales	28221|Deltaproteobacteria	H	acetyl-coa acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C
XH1_k127_3407084_9	96561.Dole_1600	3.26e-30	130.0	COG0789@1|root,COG1309@1|root,COG0789@2|Bacteria,COG1309@2|Bacteria,1RE97@1224|Proteobacteria,430U2@68525|delta/epsilon subdivisions,2WW4Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_3407084_10	439235.Dalk_3874	1.42e-24	113.0	COG0789@1|root,COG1309@1|root,COG0789@2|Bacteria,COG1309@2|Bacteria,1Q4FI@1224|Proteobacteria,42Z39@68525|delta/epsilon subdivisions,2WU4H@28221|Deltaproteobacteria,2MN4W@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TetR_N
XH1_k127_3407084_5	1322246.BN4_10599	2.563e-113	370.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2M7ZW@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
XH1_k127_3407084_2	1379281.AVAG01000017_gene983	4.215e-120	403.0	COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,42QIN@68525|delta/epsilon subdivisions,2WKVZ@28221|Deltaproteobacteria,2M97B@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
XH1_k127_3407084_0	1121413.JMKT01000008_gene1352	9.29e-188	605.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,42Q6W@68525|delta/epsilon subdivisions,2WKMV@28221|Deltaproteobacteria,2M8AI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029,ko:K10002	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
XH1_k127_3407084_3	1121447.JONL01000006_gene192	2.337e-119	387.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2M7ZW@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028,ko:K10004	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	ABC_tran
XH1_k127_3407084_4	1121451.DESAM_10082	6.354e-115	376.0	COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,42PW4@68525|delta/epsilon subdivisions,2WJPM@28221|Deltaproteobacteria,2M99Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030,ko:K10001	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	SBP_bac_3
XH1_k127_3407084_6	690850.Desaf_3720	5.858e-103	340.0	COG0765@1|root,COG0765@2|Bacteria,1MVVZ@1224|Proteobacteria,43ADK@68525|delta/epsilon subdivisions,2WNG0@28221|Deltaproteobacteria,2M8YF@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
XH1_k127_3407084_7	485915.Dret_2155	1.378e-102	338.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,42Q6W@68525|delta/epsilon subdivisions,2WQE2@28221|Deltaproteobacteria,2M82S@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029,ko:K10002	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
XH1_k127_3407084_8	1123008.KB905694_gene1793	1.23e-30	129.0	COG0370@1|root,COG0370@2|Bacteria,4NEAC@976|Bacteroidetes,2FR1T@200643|Bacteroidia,22X98@171551|Porphyromonadaceae	976|Bacteroidetes	P	Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	Gate
XH1_k127_3411521_0	198467.NP92_02235	4.997e-267	840.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,21WN2@150247|Anoxybacillus	91061|Bacilli	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
XH1_k127_3411521_3	555079.Toce_0694	3.349e-55	198.0	COG0323@1|root,COG0323@2|Bacteria,1UK25@1239|Firmicutes,25G0Z@186801|Clostridia	186801|Clostridia	L	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
XH1_k127_3411521_1	706587.Desti_2749	2.506e-56	205.0	COG0613@1|root,COG0613@2|Bacteria,1N68X@1224|Proteobacteria,42TYN@68525|delta/epsilon subdivisions,2WR34@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PHP-associated	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP_C
XH1_k127_3411521_6	706587.Desti_2748	6.383e-27	113.0	COG4109@1|root,COG4109@2|Bacteria	2|Bacteria	K	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
XH1_k127_3411521_4	1121468.AUBR01000009_gene2110	2.3e-37	145.0	COG2172@1|root,COG2172@2|Bacteria,1V6YP@1239|Firmicutes,24JJ0@186801|Clostridia,42GXK@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HATPase_c,HATPase_c_2
XH1_k127_3411521_5	1069080.KB913028_gene889	4.439e-28	121.0	COG2172@1|root,COG2172@2|Bacteria,1UJ84@1239|Firmicutes,4H9AW@909932|Negativicutes	909932|Negativicutes	T	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
XH1_k127_3411521_2	1123371.ATXH01000003_gene1897	2.096e-55	199.0	COG0288@1|root,COG0288@2|Bacteria,2GI61@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
XH1_k127_343305_1	909663.KI867150_gene1152	3.866e-124	407.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQU0@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PDZ domain (Also known as DHR or GLGF)	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
XH1_k127_343305_2	459349.CLOAM0346	1.791e-103	364.0	COG0012@1|root,COG0012@2|Bacteria,2NNNF@2323|unclassified Bacteria	2|Bacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
XH1_k127_343305_6	264462.Bd3241	3.07e-54	203.0	COG1913@1|root,COG1913@2|Bacteria,1N88E@1224|Proteobacteria,42VD8@68525|delta/epsilon subdivisions,2MU0Y@213481|Bdellovibrionales,2WR9R@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_343305_0	96561.Dole_2580	4.685e-309	953.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MHY2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
XH1_k127_343305_4	456442.Mboo_0650	3.408e-91	302.0	COG0655@1|root,arCOG02573@2157|Archaea,2XWPJ@28890|Euryarchaeota,2NAHI@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
XH1_k127_343305_9	472759.Nhal_1729	5.701e-36	143.0	COG3431@1|root,COG3431@2|Bacteria,1RJWK@1224|Proteobacteria,1S2UP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
XH1_k127_343305_8	335543.Sfum_2407	4.345e-45	170.0	COG3449@1|root,COG3449@2|Bacteria,1RF2U@1224|Proteobacteria,42S14@68525|delta/epsilon subdivisions,2WNUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
XH1_k127_343305_10	335543.Sfum_0267	1.212e-24	106.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
XH1_k127_343305_3	335543.Sfum_0266	5.851e-95	321.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42PQM@68525|delta/epsilon subdivisions,2WJIF@28221|Deltaproteobacteria,2MRCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	HTH_20,Methyltransf_31
XH1_k127_343305_11	46234.ANA_C10334	4.793e-11	67.0	COG5626@1|root,COG5626@2|Bacteria,1G7R6@1117|Cyanobacteria,1HPB8@1161|Nostocales	1117|Cyanobacteria	S	small conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2288
XH1_k127_343305_5	880073.Calab_1130	5.683e-67	241.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
XH1_k127_343305_7	1121456.ATVA01000014_gene794	2.031e-48	184.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
XH1_k127_3435771_2	706587.Desti_5085	6.189e-37	160.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,2MQEF@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
XH1_k127_3435771_0	526227.Mesil_0351	2.926e-62	229.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
XH1_k127_3435771_1	635013.TherJR_2328	1.11e-58	211.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,26062@186807|Peptococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
XH1_k127_3467350_1	639282.DEFDS_0574	2.786e-82	285.0	COG0618@1|root,COG0618@2|Bacteria,2GEP1@200930|Deferribacteres	200930|Deferribacteres	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
XH1_k127_3467350_0	269799.Gmet_1189	7.483e-120	397.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,43SCR@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
XH1_k127_3467350_2	269799.Gmet_2185	3.403e-38	149.0	COG2010@1|root,COG4733@1|root,COG2010@2|Bacteria,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
XH1_k127_3489649_0	330214.NIDE2011	1.054e-95	327.0	COG3516@1|root,COG3517@1|root,COG3516@2|Bacteria,COG3517@2|Bacteria	2|Bacteria	S	type VI secretion protein	sciH	-	-	ko:K11900,ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA,VipB
XH1_k127_3489649_3	287.DR97_243	3.352e-20	104.0	2BYGB@1|root,2ZI39@2|Bacteria,1P5HE@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF5086)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5086
XH1_k127_3489649_2	402881.Plav_0640	1.368e-57	210.0	COG3897@1|root,COG3897@2|Bacteria,1N9VC@1224|Proteobacteria,2TV6N@28211|Alphaproteobacteria,1JNYZ@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Ribosomal protein L11 methyltransferase (PrmA)	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736	-	-	-	-	-	-	-	-	-	-	PrmA
XH1_k127_3489649_1	1348663.KCH_36120	7.336e-64	234.0	COG2890@1|root,COG2890@2|Bacteria,2GJPP@201174|Actinobacteria,2M0DS@2063|Kitasatospora	201174|Actinobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	rsmC	-	-	-	-	-	-	-	-	-	-	-	MTS
XH1_k127_3494859_3	1122611.KB903957_gene50	1.076e-10	71.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4EJ41@85012|Streptosporangiales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
XH1_k127_3494859_1	1121472.AQWN01000004_gene867	2.172e-65	235.0	COG1243@1|root,COG1243@2|Bacteria,1UN0U@1239|Firmicutes,25GU0@186801|Clostridia,260N9@186807|Peptococcaceae	186801|Clostridia	BK	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
XH1_k127_3494859_2	868131.MSWAN_0302	3.922e-39	151.0	COG2246@1|root,arCOG02228@2157|Archaea,2Y20I@28890|Euryarchaeota,23PR3@183925|Methanobacteria	183925|Methanobacteria	S	PFAM GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
XH1_k127_3494859_0	309807.SRU_0841	4.677e-87	304.0	COG1232@1|root,COG1232@2|Bacteria,4NJNP@976|Bacteroidetes	976|Bacteroidetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
XH1_k127_3494859_4	44251.PDUR_24850	5.076e-06	51.0	COG5542@1|root,COG5542@2|Bacteria,1V7KR@1239|Firmicutes,4I6UF@91061|Bacilli,26V1N@186822|Paenibacillaceae	91061|Bacilli	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3509505_0	1304885.AUEY01000002_gene399	3.619e-73	255.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,42QXT@68525|delta/epsilon subdivisions,2WN0R@28221|Deltaproteobacteria,2MJ9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
XH1_k127_3509505_1	429009.Adeg_1292	2.18e-58	212.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
XH1_k127_3509505_3	1121918.ARWE01000001_gene1672	3.693e-26	111.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,42TVD@68525|delta/epsilon subdivisions,2WQPX@28221|Deltaproteobacteria,43SP9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Belongs to the bacterial histone-like protein family	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
XH1_k127_3509505_2	880072.Desac_2891	3.854e-36	142.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MQ9H@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	fgrM	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_3516065_4	319225.Plut_1200	8.071e-37	140.0	COG0389@1|root,COG0389@2|Bacteria,1FEWF@1090|Chlorobi	1090|Chlorobi	L	PFAM UMUC domain protein DNA-repair protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C
XH1_k127_3516065_3	596151.DesfrDRAFT_1284	3.424e-48	179.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,42T6V@68525|delta/epsilon subdivisions,2WPNI@28221|Deltaproteobacteria,2MC1S@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
XH1_k127_3516065_1	944479.JQLX01000017_gene262	7.415e-142	462.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria,2M6IG@213113|Desulfurellales	28221|Deltaproteobacteria	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.2.1,1.12.5.1	ko:K05927,ko:K18008	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
XH1_k127_3516065_0	204536.SULAZ_0755	2.741e-220	696.0	COG0374@1|root,COG0374@2|Bacteria,2G3UN@200783|Aquificae	200783|Aquificae	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hynL	-	1.12.5.1,1.12.99.6	ko:K05922,ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
XH1_k127_3516065_6	1336233.JAEH01000047_gene3736	5.248e-32	133.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,1RNTH@1236|Gammaproteobacteria,2Q9WX@267890|Shewanellaceae	1236|Gammaproteobacteria	C	TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit	hyaC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
XH1_k127_3516065_7	941449.dsx2_0143	2.204e-28	121.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WP4D@28221|Deltaproteobacteria,2MBIJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
XH1_k127_3516065_5	56780.SYN_00595	4.963e-34	138.0	COG0375@1|root,COG0375@2|Bacteria,1PTY5@1224|Proteobacteria,42U07@68525|delta/epsilon subdivisions,2WPIB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
XH1_k127_3516065_8	56780.SYN_00597	2.388e-27	112.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,42X24@68525|delta/epsilon subdivisions,2WSTX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
XH1_k127_3516065_2	56780.SYN_00598	1.422e-138	450.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria,2MR11@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	TIGRFAM hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
XH1_k127_3525968_2	1304888.ATWF01000001_gene1982	2.607e-39	153.0	COG0642@1|root,COG0642@2|Bacteria,2GGPY@200930|Deferribacteres	2|Bacteria	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
XH1_k127_3525968_1	439235.Dalk_0874	7.842e-89	309.0	COG0745@1|root,COG1639@1|root,COG0745@2|Bacteria,COG1639@2|Bacteria,1RC5P@1224|Proteobacteria,43AQF@68525|delta/epsilon subdivisions,2X64C@28221|Deltaproteobacteria,2MPGT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
XH1_k127_3525968_0	706587.Desti_2415	7.121e-104	347.0	COG0655@1|root,COG3255@1|root,COG0655@2|Bacteria,COG3255@2|Bacteria,1MYKZ@1224|Proteobacteria,42SN9@68525|delta/epsilon subdivisions,2WP58@28221|Deltaproteobacteria,2MRMQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,SCP2
XH1_k127_3546285_2	1268622.AVS7_01641	0.0003415	46.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria,4ADKC@80864|Comamonadaceae	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
XH1_k127_3546285_0	1128421.JAGA01000002_gene816	1.466e-162	528.0	COG1233@1|root,COG1233@2|Bacteria,2NQAT@2323|unclassified Bacteria	2|Bacteria	Q	Flavin containing amine oxidoreductase	pys	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
XH1_k127_3563414_0	96561.Dole_3101	1.205e-110	371.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2MHZ4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
XH1_k127_3563414_1	96561.Dole_2365	8.284e-85	290.0	COG1024@1|root,COG1024@2|Bacteria,1R56Y@1224|Proteobacteria,42MRW@68525|delta/epsilon subdivisions,2WKNI@28221|Deltaproteobacteria,2MJAI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_3563414_2	667632.KB890168_gene5141	1.316e-13	74.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,1K3FN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
XH1_k127_3598532_2	1265505.ATUG01000001_gene3218	6.931e-77	266.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,2MJTU@213118|Desulfobacterales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
XH1_k127_3598532_0	96561.Dole_1686	4.489e-95	322.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria	1224|Proteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
XH1_k127_3598532_1	96561.Dole_1685	2.104e-87	306.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria,2MNG5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
XH1_k127_3598532_3	1298593.TOL_1965	3.098e-62	224.0	COG4221@1|root,COG4221@2|Bacteria,1R2U2@1224|Proteobacteria,1T5XP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
XH1_k127_3598532_4	96561.Dole_0015	3.344e-38	150.0	COG2128@1|root,COG2128@2|Bacteria,1NET8@1224|Proteobacteria	1224|Proteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
XH1_k127_3633084_6	883.DvMF_1980	8.374e-17	84.0	2DF2N@1|root,2ZQ8C@2|Bacteria,1P53S@1224|Proteobacteria,432BG@68525|delta/epsilon subdivisions,2WXE4@28221|Deltaproteobacteria,2MDTM@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3633084_0	867902.Ornrh_1344	7.37e-102	357.0	COG1368@1|root,COG1368@2|Bacteria,4NK5V@976|Bacteroidetes,1I54F@117743|Flavobacteriia	976|Bacteroidetes	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
XH1_k127_3633084_2	335543.Sfum_0349	1.301e-52	188.0	COG4802@1|root,COG4802@2|Bacteria,1RI70@1224|Proteobacteria,42SXJ@68525|delta/epsilon subdivisions,2WP19@28221|Deltaproteobacteria,2MS00@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
XH1_k127_3633084_5	1121405.dsmv_3379	1.987e-23	105.0	COG0695@1|root,COG0695@2|Bacteria,1NAZM@1224|Proteobacteria,42VIA@68525|delta/epsilon subdivisions,2WR8X@28221|Deltaproteobacteria,2MKPI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM Glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
XH1_k127_3633084_4	1121405.dsmv_0930	4.482e-42	161.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2WQGH@28221|Deltaproteobacteria,2MJJ6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
XH1_k127_3633084_3	1265505.ATUG01000002_gene2007	2.464e-43	165.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria,2MKAW@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
XH1_k127_3633084_1	706587.Desti_3072	2.975e-72	258.0	COG0784@1|root,COG5000@1|root,COG0784@2|Bacteria,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,42YHZ@68525|delta/epsilon subdivisions,2WTS8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
XH1_k127_3655337_8	644282.Deba_2013	4.802e-32	136.0	COG0745@1|root,COG2203@1|root,COG2206@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
XH1_k127_3655337_10	1047013.AQSP01000115_gene361	8.044e-24	109.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_3655337_3	933262.AXAM01000030_gene807	1.618e-82	285.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2MI3R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
XH1_k127_3655337_7	621372.ACIH01000090_gene2944	2.048e-32	136.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,26XDH@186822|Paenibacillaceae	91061|Bacilli	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
XH1_k127_3655337_2	338963.Pcar_3127	1.941e-88	302.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,43UJB@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
XH1_k127_3655337_12	1121440.AUMA01000002_gene2302	7.491e-09	67.0	2AKQ6@1|root,31BGX@2|Bacteria,1RCS3@1224|Proteobacteria,43CF4@68525|delta/epsilon subdivisions,2WP3G@28221|Deltaproteobacteria,2MHAR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4
XH1_k127_3655337_6	1347392.CCEZ01000074_gene1861	1.838e-48	182.0	COG0634@1|root,COG0634@2|Bacteria,1V2K7@1239|Firmicutes,248P7@186801|Clostridia,36F2B@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16720	Pribosyltran
XH1_k127_3655337_13	264462.Bd2545	0.0007563	48.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2MTPI@213481|Bdellovibrionales,2WJPC@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,PilZ
XH1_k127_3655337_9	498211.CJA_3583	5.569e-24	113.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1FFZF@10|Cellvibrio	1236|Gammaproteobacteria	S	LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	LysM
XH1_k127_3655337_11	96561.Dole_0338	5.51e-18	89.0	2FHTG@1|root,349KR@2|Bacteria,1P1C2@1224|Proteobacteria,4318F@68525|delta/epsilon subdivisions,2WWJT@28221|Deltaproteobacteria,2MNZ8@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3655337_1	941449.dsx2_1512	1.637e-177	574.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2M8F2@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
XH1_k127_3655337_5	1232410.KI421418_gene2310	1.826e-63	228.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria,43S2J@69541|Desulfuromonadales	28221|Deltaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
XH1_k127_3655337_0	935948.KE386494_gene652	1.97e-213	672.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,42EYV@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
XH1_k127_3655337_4	515635.Dtur_1391	1.168e-74	257.0	COG0587@1|root,COG0587@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
XH1_k127_3684929_2	96561.Dole_1605	2.037e-77	265.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2MMK1@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
XH1_k127_3684929_0	96561.Dole_1604	2.003e-175	558.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	acyl-coa dehydrogenase	caiA	GO:0003674,GO:0003824,GO:0006066,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0016627,GO:0034308,GO:0034309,GO:0044281,GO:0044283,GO:0046165,GO:0052890,GO:0055114,GO:0071270,GO:0071271,GO:0071704,GO:1901576,GO:1901615,GO:1901617	1.3.8.13	ko:K08297	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_3684929_1	96561.Dole_1603	4.38e-106	352.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_3684929_3	96561.Dole_1602	3.257e-68	234.0	COG1545@1|root,COG1545@2|Bacteria,1RB09@1224|Proteobacteria,437V5@68525|delta/epsilon subdivisions,2X34N@28221|Deltaproteobacteria,2MNPW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
XH1_k127_3720738_1	868595.Desca_0025	2.17e-38	151.0	COG0778@1|root,COG0778@2|Bacteria,1V0Y6@1239|Firmicutes,24HMV@186801|Clostridia,261V8@186807|Peptococcaceae	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
XH1_k127_3720738_0	1177154.Y5S_03661	5.23e-45	174.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
XH1_k127_3720738_2	1198114.AciX9_2049	6.458e-05	56.0	COG1305@1|root,COG1305@2|Bacteria,3Y3A2@57723|Acidobacteria,2JHZ8@204432|Acidobacteriia	204432|Acidobacteriia	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
XH1_k127_3721069_1	439235.Dalk_1924	5.83e-102	336.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2WJ1Z@28221|Deltaproteobacteria,2MHWH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
XH1_k127_3721069_3	667014.Thein_0275	4.775e-41	157.0	COG0244@1|root,COG0244@2|Bacteria,2GH1K@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
XH1_k127_3721069_2	1123372.AUIT01000011_gene1527	4.115e-44	164.0	COG0222@1|root,COG0222@2|Bacteria,2GHVX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
XH1_k127_3721069_0	243231.GSU2863	0.0	1683.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,43T41@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
XH1_k127_3730099_3	391625.PPSIR1_41444	7.609e-27	119.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,42ZU5@68525|delta/epsilon subdivisions,2WV5X@28221|Deltaproteobacteria,2YUT0@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
XH1_k127_3730099_2	1260251.SPISAL_08250	6.068e-57	211.0	COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1RYBE@1236|Gammaproteobacteria,1X2D8@135613|Chromatiales	135613|Chromatiales	L	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
XH1_k127_3730099_0	439235.Dalk_2571	4.547e-163	520.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2MI40@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
XH1_k127_3730099_1	335543.Sfum_3728	1.427e-134	442.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42PMA@68525|delta/epsilon subdivisions,2X5AR@28221|Deltaproteobacteria,2MRG6@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
XH1_k127_3734552_2	264732.Moth_1122	2.225e-101	343.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,42HUS@68295|Thermoanaerobacterales	186801|Clostridia	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
XH1_k127_3734552_1	56780.SYN_00384	2.391e-115	387.0	COG3359@1|root,COG3359@2|Bacteria,1R5KG@1224|Proteobacteria,4309C@68525|delta/epsilon subdivisions,2WVJ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
XH1_k127_3734552_0	56780.SYN_00383	2.164e-248	773.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria	1224|Proteobacteria	L	dEAD DEAH box helicase	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
XH1_k127_3740407_3	706587.Desti_5626	8.151e-47	171.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MQUN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase beta subunit	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
XH1_k127_3740407_1	289377.HL41_02225	2.251e-139	452.0	COG0674@1|root,COG0674@2|Bacteria,2GGZK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	ferredoxin oxidoreductase	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
XH1_k127_3740407_5	909663.KI867149_gene3396	3.861e-35	136.0	COG1144@1|root,COG1144@2|Bacteria,1N99V@1224|Proteobacteria,42V8C@68525|delta/epsilon subdivisions,2WRCP@28221|Deltaproteobacteria,2MS61@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
XH1_k127_3740407_2	1121456.ATVA01000013_gene1030	1.511e-60	214.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WQFN@28221|Deltaproteobacteria,2M92T@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,POR
XH1_k127_3740407_6	290397.Adeh_3940	4.024e-33	137.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,2YW3V@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
XH1_k127_3740407_4	370438.PTH_0063	6.029e-40	160.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,26259@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
XH1_k127_3740407_0	335543.Sfum_0068	2.264e-199	639.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MR6X@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
XH1_k127_374043_7	439235.Dalk_3192	8.321e-11	72.0	COG1028@1|root,COG2030@1|root,COG3255@1|root,COG1028@2|Bacteria,COG2030@2|Bacteria,COG3255@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria,2MHRA@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas,SCP2,adh_short
XH1_k127_374043_6	439235.Dalk_3343	1.466e-18	96.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
XH1_k127_374043_5	439235.Dalk_4046	1.973e-30	136.0	COG1545@1|root,COG1545@2|Bacteria,1NFZC@1224|Proteobacteria,42ZH0@68525|delta/epsilon subdivisions,2WV3P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	OB_aCoA_assoc
XH1_k127_374043_0	439235.Dalk_3351	1.016e-134	443.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,42QYC@68525|delta/epsilon subdivisions,2WN66@28221|Deltaproteobacteria,2MMVX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pfam:Kce	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
XH1_k127_374043_3	330214.NIDE3102	1.055e-69	244.0	COG1024@1|root,COG1024@2|Bacteria,3J1EP@40117|Nitrospirae	40117|Nitrospirae	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K13767,ko:K13816	ko00071,ko00362,ko01100,ko01120,ko01212,ko02020,ko02024,map00071,map00362,map01100,map01120,map01212,map02020,map02024	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
XH1_k127_374043_1	1210884.HG799463_gene10153	1.417e-118	390.0	COG1788@1|root,COG1788@2|Bacteria	2|Bacteria	I	CoA-transferase activity	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
XH1_k127_374043_2	944480.ATUV01000001_gene603	8.085e-110	360.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2M734@213113|Desulfurellales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
XH1_k127_374043_4	706587.Desti_5427	4.675e-35	139.0	COG1545@1|root,COG1545@2|Bacteria,1NFZC@1224|Proteobacteria,42ZH0@68525|delta/epsilon subdivisions,2WV3P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	OB_aCoA_assoc
XH1_k127_3756672_6	439235.Dalk_3423	5.902e-30	124.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,42MN2@68525|delta/epsilon subdivisions,2WIMJ@28221|Deltaproteobacteria,2MHYD@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
XH1_k127_3756672_4	439235.Dalk_3424	3.906e-51	189.0	COG1556@1|root,COG1556@2|Bacteria,1RJ6A@1224|Proteobacteria,42VHI@68525|delta/epsilon subdivisions,2WSAQ@28221|Deltaproteobacteria,2MMEU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pfam:DUF162	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
XH1_k127_3756672_5	1128398.Curi_c16640	5.24e-51	196.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,26CSW@186813|unclassified Clostridiales	186801|Clostridia	C	Molybdopterin oxidoreductase Fe4S4 domain	nuoG	-	1.17.1.10,1.17.1.11,1.6.5.3	ko:K00336,ko:K05299,ko:K22341	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
XH1_k127_3756672_7	1408473.JHXO01000006_gene1329	2.308e-25	119.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,2FXUE@200643|Bacteroidia	976|Bacteroidetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
XH1_k127_3756672_1	697281.Mahau_1382	1.119e-122	406.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,42EM7@68295|Thermoanaerobacterales	1239|Firmicutes	C	NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding	nqo1	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
XH1_k127_3756672_0	1123274.KB899416_gene2614	3.918e-199	648.0	COG1529@1|root,COG1529@2|Bacteria,2J9MJ@203691|Spirochaetes	203691|Spirochaetes	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
XH1_k127_3756672_3	1123274.KB899416_gene2613	2.323e-62	221.0	COG2080@1|root,COG2080@2|Bacteria,2JAIS@203691|Spirochaetes	203691|Spirochaetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
XH1_k127_3756672_2	1123274.KB899416_gene2615	4.903e-95	323.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
XH1_k127_3762549_5	56780.SYN_01472	3.288e-17	85.0	COG1317@1|root,COG1317@2|Bacteria,1PD92@1224|Proteobacteria,42V2C@68525|delta/epsilon subdivisions,2X2GZ@28221|Deltaproteobacteria,2MSFG@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
XH1_k127_3762549_0	401526.TcarDRAFT_2138	3.402e-167	537.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,4H2V3@909932|Negativicutes	909932|Negativicutes	N	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
XH1_k127_3762549_7	439292.Bsel_1745	8.729e-05	50.0	COG2882@1|root,COG2882@2|Bacteria,1V6SQ@1239|Firmicutes,4HN1W@91061|Bacilli	91061|Bacilli	NOU	Flagellar FliJ protein	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
XH1_k127_3762549_6	596152.DesU5LDRAFT_0848	1.473e-13	78.0	COG3334@1|root,COG3334@2|Bacteria,1NM9I@1224|Proteobacteria,42TYQ@68525|delta/epsilon subdivisions,2WQG2@28221|Deltaproteobacteria,2MC8V@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM MgtE intracellular	-	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
XH1_k127_3762549_2	706587.Desti_5003	3.147e-66	239.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria,2MQUF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Radical SAM superfamily	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
XH1_k127_3762549_1	56780.SYN_02643	4.055e-112	379.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ00@28221|Deltaproteobacteria,2MR5D@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
XH1_k127_3762549_3	706587.Desti_4215	3.45e-49	182.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria	1224|Proteobacteria	P	phosphate transport regulator (Distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
XH1_k127_3762549_4	879212.DespoDRAFT_00996	3.571e-25	111.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,2MIC2@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
XH1_k127_3764877_0	694431.DESACE_01345	3.352e-70	247.0	COG4796@1|root,COG4796@2|Bacteria,1QUXY@1224|Proteobacteria,43D2W@68525|delta/epsilon subdivisions,2WNS3@28221|Deltaproteobacteria,2M6MR@213113|Desulfurellales	28221|Deltaproteobacteria	U	Bacterial type II and III secretion system protein	-	-	-	ko:K12282	-	-	-	-	ko00000,ko02044	-	-	-	Secretin
XH1_k127_3764877_1	1304888.ATWF01000001_gene715	4.873e-41	162.0	COG0613@1|root,COG0613@2|Bacteria,2GFGU@200930|Deferribacteres	200930|Deferribacteres	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
XH1_k127_3764877_2	56780.SYN_01766	2.033e-29	121.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2WK5J@28221|Deltaproteobacteria,2MQ5V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
XH1_k127_3801346_0	56780.SYN_00872	6.841e-302	937.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2MQVC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Cation transporter/ATPase, N-terminus	ctpF	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
XH1_k127_3819412_0	448385.sce1547	4.203e-113	384.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YZVC@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
XH1_k127_3819412_1	748658.KB907313_gene2061	1.463e-30	129.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,1T1YU@1236|Gammaproteobacteria,1WXQM@135613|Chromatiales	135613|Chromatiales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
XH1_k127_3822743_0	1499967.BAYZ01000030_gene1176	2.924e-121	415.0	COG1033@1|root,COG1033@2|Bacteria,2NQ2I@2323|unclassified Bacteria	2|Bacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	LolA_like,MMPL,Polyketide_cyc2
XH1_k127_3822743_2	247490.KSU1_C0780	6.104e-79	294.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	-	-	-	ko:K07289,ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA,AsmA_1,AsmA_2,DUF3971,DctA-YdbH
XH1_k127_3822743_5	1121918.ARWE01000001_gene3280	2.832e-35	136.0	2DREH@1|root,33BDY@2|Bacteria,1Q6K1@1224|Proteobacteria,433AU@68525|delta/epsilon subdivisions,2WXFM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3822743_3	1121918.ARWE01000001_gene3281	3.546e-56	202.0	2DQBG@1|root,335T7@2|Bacteria,1N795@1224|Proteobacteria,42VWE@68525|delta/epsilon subdivisions,2WRT6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	-	-	-	-	-	-	-	-	-	-	GRDB
XH1_k127_3822743_4	861299.J421_0815	9.305e-42	155.0	COG1359@1|root,COG1359@2|Bacteria,1ZU18@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
XH1_k127_3822743_1	1499967.BAYZ01000118_gene3300	4.804e-110	364.0	COG1454@1|root,COG1454@2|Bacteria,2NQ5W@2323|unclassified Bacteria	2|Bacteria	C	Iron-containing alcohol dehydrogenase	CT0951	-	1.1.1.1,4.3.3.7	ko:K00001,ko:K01714,ko:K13954	ko00010,ko00071,ko00261,ko00300,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,ko01230,map00010,map00071,map00261,map00300,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220,map01230	M00016,M00525,M00526,M00527	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10147	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
XH1_k127_38377_1	1265505.ATUG01000001_gene4584	6.521e-229	712.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,42M4A@68525|delta/epsilon subdivisions,2WJKU@28221|Deltaproteobacteria,2MIKN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Type VI secretion protein, EvpB/VC_A0108, tail sheath	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA,VipB
XH1_k127_38377_2	443143.GM18_3029	2.42e-61	216.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,42XEQ@68525|delta/epsilon subdivisions,2WTD9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
XH1_k127_38377_3	1265505.ATUG01000001_gene4585	5.67e-35	141.0	COG3518@1|root,COG3518@2|Bacteria,1PT65@1224|Proteobacteria,42XTG@68525|delta/epsilon subdivisions,2WSNC@28221|Deltaproteobacteria,2MP91@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Gene 25-like lysozyme	-	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
XH1_k127_38377_0	1265505.ATUG01000001_gene4586	3.353e-248	779.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,42PR4@68525|delta/epsilon subdivisions,2WJCN@28221|Deltaproteobacteria,2MJYU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Type VI secretion system, TssF	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
XH1_k127_38377_4	404380.Gbem_3038	9.333e-33	132.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,42UKI@68525|delta/epsilon subdivisions,2WQ70@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	type VI secretion protein	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
XH1_k127_3867182_3	644968.DFW101_1367	1.118e-71	243.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,2M7UU@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
XH1_k127_3867182_4	1232410.KI421421_gene3262	1.415e-65	230.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2WK0G@28221|Deltaproteobacteria,43SJH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
XH1_k127_3867182_0	443144.GM21_2170	2.942e-94	335.0	COG0515@1|root,COG0515@2|Bacteria,1N9V2@1224|Proteobacteria,42Q0B@68525|delta/epsilon subdivisions,2WJXJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3867182_1	644282.Deba_2232	1.667e-87	299.0	COG1148@1|root,COG1148@2|Bacteria,1R9EV@1224|Proteobacteria,42PIR@68525|delta/epsilon subdivisions,2WK4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
XH1_k127_3867182_6	485916.Dtox_2551	3.905e-20	95.0	COG0640@1|root,COG0640@2|Bacteria,1VD5U@1239|Firmicutes,24PZ1@186801|Clostridia	186801|Clostridia	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
XH1_k127_3867182_7	1121396.KB893051_gene3443	3.216e-16	82.0	COG0316@1|root,COG0316@2|Bacteria,1N8FK@1224|Proteobacteria,42VBF@68525|delta/epsilon subdivisions,2WR7Y@28221|Deltaproteobacteria,2MKTJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the HesB IscA family	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
XH1_k127_3867182_8	909663.KI867150_gene1170	1.616e-15	78.0	COG0316@1|root,COG0316@2|Bacteria,1QF3E@1224|Proteobacteria,4362W@68525|delta/epsilon subdivisions,2X390@28221|Deltaproteobacteria,2MSFS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Belongs to the HesB IscA family	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3867182_2	909663.KI867150_gene1144	1.839e-84	292.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42STT@68525|delta/epsilon subdivisions,2WPJI@28221|Deltaproteobacteria,2MQHI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
XH1_k127_3867182_5	401526.TcarDRAFT_1997	2.433e-52	187.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4H20U@909932|Negativicutes	1239|Firmicutes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
XH1_k127_3867211_2	1121439.dsat_2575	1.119e-10	62.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2M8ZX@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
XH1_k127_3867211_0	1121405.dsmv_1958	3.43e-153	502.0	COG0348@1|root,COG1148@1|root,COG3383@1|root,COG0348@2|Bacteria,COG1148@2|Bacteria,COG3383@2|Bacteria,1QUNB@1224|Proteobacteria,43BMZ@68525|delta/epsilon subdivisions,2X701@28221|Deltaproteobacteria,2MPPX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_5
XH1_k127_3867211_1	1385515.N791_04555	7.966e-49	193.0	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,1RZDR@1236|Gammaproteobacteria,1X5RQ@135614|Xanthomonadales	135614|Xanthomonadales	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_6,SH3_7
XH1_k127_3867211_3	1499967.BAYZ01000136_gene20	5.086e-08	61.0	COG1033@1|root,COG1033@2|Bacteria,2NQ2I@2323|unclassified Bacteria	2|Bacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
XH1_k127_3873816_7	536227.CcarbDRAFT_1844	2.443e-05	47.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,36EYM@31979|Clostridiaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
XH1_k127_3873816_2	1449126.JQKL01000011_gene3566	2.934e-91	314.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,267ZV@186813|unclassified Clostridiales	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	noxE	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
XH1_k127_3873816_0	439235.Dalk_4976	2.387e-149	481.0	COG1145@1|root,COG1145@2|Bacteria,1MW11@1224|Proteobacteria,42NUY@68525|delta/epsilon subdivisions,2WK01@28221|Deltaproteobacteria,2MMY1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
XH1_k127_3873816_4	391623.TERMP_00349	4.393e-55	198.0	COG1225@1|root,arCOG00310@2157|Archaea,2XY0E@28890|Euryarchaeota,2440M@183968|Thermococci	183968|Thermococci	O	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
XH1_k127_3873816_6	1048339.KB913029_gene3467	1.653e-09	64.0	2FIJ7@1|root,34AB9@2|Bacteria,2GUPT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3873816_3	439235.Dalk_3586	8.075e-91	313.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2MIC8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh,Fe-ADH
XH1_k127_3873816_5	565033.GACE_1085	4.468e-19	92.0	COG3255@1|root,arCOG01842@2157|Archaea,2XXJM@28890|Euryarchaeota,2468P@183980|Archaeoglobi	183980|Archaeoglobi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
XH1_k127_3873816_1	397948.Cmaq_0710	8.02e-100	342.0	COG2414@1|root,arCOG00706@2157|Archaea,2XQ6E@28889|Crenarchaeota	28889|Crenarchaeota	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
XH1_k127_3877035_1	96561.Dole_1550	5.191e-101	336.0	COG1028@1|root,COG1545@1|root,COG3255@1|root,COG3425@1|root,COG1028@2|Bacteria,COG1545@2|Bacteria,COG3255@2|Bacteria,COG3425@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria,2MHRA@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,MaoC_dehydrat_N,MaoC_dehydratas,OB_aCoA_assoc,SCP2,adh_short
XH1_k127_3877035_0	1304885.AUEY01000005_gene880	2.722e-135	443.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,42PNZ@68525|delta/epsilon subdivisions,2WM13@28221|Deltaproteobacteria,2MJSE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
XH1_k127_3877035_2	56780.SYN_00817	8.321e-28	125.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,42RYD@68525|delta/epsilon subdivisions,2X5EZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
XH1_k127_3907608_1	706587.Desti_3540	4.133e-94	317.0	COG1600@1|root,COG1600@2|Bacteria,1RAYI@1224|Proteobacteria,42R4W@68525|delta/epsilon subdivisions,2WK0B@28221|Deltaproteobacteria,2MSDE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3907608_3	401526.TcarDRAFT_2228	1.487e-06	57.0	COG2755@1|root,COG2755@2|Bacteria,1VDE2@1239|Firmicutes,4H4RY@909932|Negativicutes	909932|Negativicutes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
XH1_k127_3907608_2	706587.Desti_1023	7.059e-24	103.0	COG1036@1|root,COG1036@2|Bacteria	2|Bacteria	C	dihydromethanopterin reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Flavoprotein
XH1_k127_3907608_0	443143.GM18_3132	9.361e-122	398.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EJ	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
XH1_k127_3912230_1	96561.Dole_1398	8.187e-15	79.0	COG1359@1|root,COG1359@2|Bacteria,1N6SG@1224|Proteobacteria,437C6@68525|delta/epsilon subdivisions,2X2HP@28221|Deltaproteobacteria,2MM80@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
XH1_k127_3912230_0	1304885.AUEY01000003_gene443	5.058e-43	162.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42NU8@68525|delta/epsilon subdivisions,2WM5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	flagellar motor	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
XH1_k127_3926294_0	96561.Dole_1921	1.554e-188	594.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,42NKV@68525|delta/epsilon subdivisions,2WKPA@28221|Deltaproteobacteria,2MIDW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_3926294_5	644282.Deba_1702	1.543e-57	208.0	COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,42TAR@68525|delta/epsilon subdivisions,2WPQT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
XH1_k127_3926294_6	96561.Dole_1923	2.683e-52	196.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42TAA@68525|delta/epsilon subdivisions,2WPDQ@28221|Deltaproteobacteria,2MKQY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
XH1_k127_3926294_4	644282.Deba_1700	6.019e-69	245.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42SNP@68525|delta/epsilon subdivisions,2WPPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
XH1_k127_3926294_7	96561.Dole_1599	3.329e-47	180.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,430NR@68525|delta/epsilon subdivisions,2WW11@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
XH1_k127_3926294_2	1304885.AUEY01000047_gene84	2.269e-77	264.0	29CZA@1|root,2ZZXB@2|Bacteria,1RFNE@1224|Proteobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3926294_3	56780.SYN_00591	5.19e-77	262.0	COG1225@1|root,COG1225@2|Bacteria,1N9JS@1224|Proteobacteria,42R82@68525|delta/epsilon subdivisions,2WMVA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
XH1_k127_3926294_8	56780.SYN_00592	2.484e-33	138.0	COG1225@1|root,COG1225@2|Bacteria,1N3ZR@1224|Proteobacteria,42TQK@68525|delta/epsilon subdivisions,2WQSX@28221|Deltaproteobacteria,2MRX5@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
XH1_k127_3926294_1	96561.Dole_2647	8.404e-101	330.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2MHUF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_3926294_9	1150474.JQJI01000004_gene390	5.537e-18	86.0	COG0735@1|root,COG0735@2|Bacteria,2GDE9@200918|Thermotogae	200918|Thermotogae	P	Belongs to the Fur family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
XH1_k127_3928597_2	439235.Dalk_1728	1.171e-47	174.0	COG1180@1|root,COG1180@2|Bacteria,1QJHU@1224|Proteobacteria,42R2E@68525|delta/epsilon subdivisions,2WMYN@28221|Deltaproteobacteria,2MMZ6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
XH1_k127_3928597_0	439235.Dalk_1731	0.0	1181.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,2MI4X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM formate C-acetyltransferase glycine radical	-	-	2.3.1.54,4.1.99.11	ko:K00656,ko:K07540	ko00620,ko00623,ko00640,ko00650,ko01100,ko01120,ko01220,map00620,map00623,map00640,map00650,map01100,map01120,map01220	M00418	R00212,R05598,R06987	RC00004,RC01181,RC01433,RC01434,RC02742,RC02833	ko00000,ko00001,ko00002,ko01000	-	-	-	Gly_radical,PFL-like
XH1_k127_3928597_1	439235.Dalk_2195	5.733e-100	329.0	COG0714@1|root,COG0714@2|Bacteria,1QAW5@1224|Proteobacteria,42PY2@68525|delta/epsilon subdivisions,2WKGF@28221|Deltaproteobacteria,2MINU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CbbQ/NirQ/NorQ C-terminal	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
XH1_k127_3951532_0	96561.Dole_2535	9.13e-197	625.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,42NEJ@68525|delta/epsilon subdivisions,2WM86@28221|Deltaproteobacteria,2MJ18@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
XH1_k127_3951532_1	797209.ZOD2009_06112	1.272e-80	278.0	COG1073@1|root,arCOG01658@2157|Archaea,2XUBM@28890|Euryarchaeota,23SZT@183963|Halobacteria	183963|Halobacteria	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S15
XH1_k127_3954251_3	1167006.UWK_02709	2.331e-71	245.0	COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,42PGN@68525|delta/epsilon subdivisions,2WKIA@28221|Deltaproteobacteria,2MM4K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	tssK	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
XH1_k127_3954251_4	269799.Gmet_0273	8.708e-62	219.0	COG3455@1|root,COG3455@2|Bacteria,1RGIR@1224|Proteobacteria,42S3K@68525|delta/epsilon subdivisions,2WNQ8@28221|Deltaproteobacteria,43VRK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Type VI secretion system protein DotU	tssL	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
XH1_k127_3954251_0	269799.Gmet_0274	0.0	1033.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,42PG2@68525|delta/epsilon subdivisions,2WM2G@28221|Deltaproteobacteria,43UWY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ImcF-related N-terminal domain	tssM	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
XH1_k127_3954251_7	269799.Gmet_0275	5.24e-33	138.0	COG3515@1|root,COG3913@1|root,COG3515@2|Bacteria,COG3913@2|Bacteria,1NKX3@1224|Proteobacteria,42VHK@68525|delta/epsilon subdivisions,2WRXN@28221|Deltaproteobacteria,43VHU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ImpA, N-terminal, type VI secretion system	-	-	-	ko:K11910	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	DUF2094,ImpA_N,T6SS_VasJ
XH1_k127_3954251_5	330214.NIDE1975	1.336e-46	178.0	COG4455@1|root,COG4455@2|Bacteria	2|Bacteria	U	Protein of avirulence locus involved in temperature-dependent protein secretion	impE	-	-	ko:K03217,ko:K11898	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	ImpE,TPR_19
XH1_k127_3954251_1	1265505.ATUG01000001_gene4582	6.703e-128	424.0	COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,42VE0@68525|delta/epsilon subdivisions,2WSAE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ImpA, N-terminal, type VI secretion system	-	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N,T6SS_VasJ
XH1_k127_3954251_2	1265505.ATUG01000001_gene4583	4.946e-79	266.0	COG3516@1|root,COG3516@2|Bacteria,1R9Y7@1224|Proteobacteria,42UQR@68525|delta/epsilon subdivisions,2WQYW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
XH1_k127_3954251_6	1265505.ATUG01000001_gene4584	1.197e-40	153.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,42M4A@68525|delta/epsilon subdivisions,2WJKU@28221|Deltaproteobacteria,2MIKN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Type VI secretion protein, EvpB/VC_A0108, tail sheath	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA,VipB
XH1_k127_3965013_3	269799.Gmet_2211	9.333e-14	74.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
XH1_k127_3965013_1	1304885.AUEY01000013_gene3104	8.394e-115	374.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria,2MIFH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
XH1_k127_3965013_4	439235.Dalk_3279	6.735e-05	46.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,42NT5@68525|delta/epsilon subdivisions,2WIWR@28221|Deltaproteobacteria,2MHQV@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	alkK	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
XH1_k127_3965013_0	1121472.AQWN01000006_gene1669	1.418e-156	503.0	COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,24E5F@186801|Clostridia,2618E@186807|Peptococcaceae	186801|Clostridia	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_3965013_2	96561.Dole_1672	2.006e-27	117.0	COG0318@1|root,COG0318@2|Bacteria,1NSB4@1224|Proteobacteria,42YPZ@68525|delta/epsilon subdivisions,2WU8S@28221|Deltaproteobacteria,2MMNJ@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_3969562_2	1120999.JONM01000010_gene4042	2.603e-81	281.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,2KPU8@206351|Neisseriales	206351|Neisseriales	S	Phospholipase, patatin family	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
XH1_k127_3969562_4	1121440.AUMA01000016_gene188	4.386e-73	255.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,42QU8@68525|delta/epsilon subdivisions,2X5Q5@28221|Deltaproteobacteria,2MGUA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
XH1_k127_3969562_5	1238182.C882_0258	1.382e-38	158.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2JQW0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
XH1_k127_3969562_0	756272.Plabr_0942	1.662e-253	816.0	COG0841@1|root,COG0841@2|Bacteria,2IY0K@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
XH1_k127_3969562_7	945713.IALB_2856	1.889e-12	71.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF3240,P-II
XH1_k127_3969562_8	1298608.JCM18900_27	8.931e-09	63.0	COG3637@1|root,COG3637@2|Bacteria,1NC11@1224|Proteobacteria,1SIFY@1236|Gammaproteobacteria,3NT6V@468|Moraxellaceae	1236|Gammaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
XH1_k127_3969562_1	439235.Dalk_2030	3.039e-243	762.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,42M2C@68525|delta/epsilon subdivisions,2WIVE@28221|Deltaproteobacteria,2MHVG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2834	Prismane
XH1_k127_3969562_6	293826.Amet_4264	1.73e-25	110.0	COG2350@1|root,COG2350@2|Bacteria,1VJ1A@1239|Firmicutes,24WYY@186801|Clostridia	186801|Clostridia	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
XH1_k127_3969562_3	1379698.RBG1_1C00001G1211	1.555e-73	254.0	COG0034@1|root,COG0034@2|Bacteria,2NNSY@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iSB619.SA_RS05225	GATase_6,GATase_7,Pribosyltran
XH1_k127_3988045_1	96561.Dole_3103	1.636e-90	310.0	COG1960@1|root,COG1960@2|Bacteria,1PUXP@1224|Proteobacteria,42YQ2@68525|delta/epsilon subdivisions,2WUBI@28221|Deltaproteobacteria,2MMS0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_3988045_0	96561.Dole_3102	2.929e-142	465.0	COG1960@1|root,COG1960@2|Bacteria,1NCCF@1224|Proteobacteria,42YB2@68525|delta/epsilon subdivisions,2WUMQ@28221|Deltaproteobacteria,2MMJJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
XH1_k127_3988045_2	439235.Dalk_2185	1.772e-07	54.0	2DM2Z@1|root,31HGC@2|Bacteria,1N0CJ@1224|Proteobacteria,42TZ3@68525|delta/epsilon subdivisions,2WQCR@28221|Deltaproteobacteria,2MKII@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4125
XH1_k127_4011406_2	522772.Dacet_1504	2.668e-18	97.0	COG0795@1|root,COG0795@2|Bacteria,2GF8W@200930|Deferribacteres	200930|Deferribacteres	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
XH1_k127_4011406_3	36875.HQ29_05790	2.783e-08	66.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,2FM2K@200643|Bacteroidia,22WPG@171551|Porphyromonadaceae	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
XH1_k127_4011406_1	56780.SYN_02917	3.279e-155	501.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,42N2K@68525|delta/epsilon subdivisions,2WJ5D@28221|Deltaproteobacteria,2MR6D@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	DAO,FAD_binding_2,GIDA,HI0933_like,Pyr_redox_2
XH1_k127_4011406_0	243231.GSU0580	0.0	1208.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,43TQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
XH1_k127_401490_1	439235.Dalk_4295	4.585e-197	628.0	COG2303@1|root,COG2303@2|Bacteria,1NV3A@1224|Proteobacteria,42NVR@68525|delta/epsilon subdivisions,2WM9A@28221|Deltaproteobacteria,2MMWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
XH1_k127_401490_0	706587.Desti_4083	0.0	1137.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MQ7V@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
XH1_k127_401490_3	944479.JQLX01000014_gene1499	3.066e-25	111.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WNC2@28221|Deltaproteobacteria,2M73U@213113|Desulfurellales	28221|Deltaproteobacteria	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
XH1_k127_401490_2	96561.Dole_2001	4.651e-75	255.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42M9N@68525|delta/epsilon subdivisions,2WIZR@28221|Deltaproteobacteria,2MHKG@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
XH1_k127_4016078_1	1120973.AQXL01000131_gene2097	4.838e-56	200.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,278T0@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
XH1_k127_4016078_3	1009370.ALO_04371	5.861e-45	168.0	COG4752@1|root,COG4752@2|Bacteria,1V1PD@1239|Firmicutes,4H3ZS@909932|Negativicutes	909932|Negativicutes	S	SAM-dependent RNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrn_RNA_4
XH1_k127_4016078_4	555079.Toce_1070	6.963e-36	139.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,42GJ8@68295|Thermoanaerobacterales	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
XH1_k127_4016078_2	595536.ADVE02000001_gene2863	2.383e-51	188.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,36YDE@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Ribonuclease HII	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
XH1_k127_4016078_6	938288.HG326227_gene451	1.848e-18	91.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,269FC@186813|unclassified Clostridiales	186801|Clostridia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
XH1_k127_4016078_5	335543.Sfum_0072	4.553e-25	111.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,42RIS@68525|delta/epsilon subdivisions,2WMWC@28221|Deltaproteobacteria,2MQMS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
XH1_k127_4016078_0	443143.GM18_1937	1.911e-75	266.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,43SCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
XH1_k127_4019576_4	1379698.RBG1_1C00001G1750	2.12e-07	57.0	COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
XH1_k127_4019576_0	945713.IALB_0545	6.756e-81	277.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
XH1_k127_4019576_1	1177181.T9A_00767	1.652e-50	191.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1XIRB@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
XH1_k127_4019576_2	2325.TKV_c13950	7.444e-19	93.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,42H3Z@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
XH1_k127_4019576_3	1121920.AUAU01000016_gene1292	8.689e-17	80.0	COG0333@1|root,COG0333@2|Bacteria,3Y5W0@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
XH1_k127_4153763_6	439235.Dalk_3422	4.457e-83	281.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PNX@68525|delta/epsilon subdivisions,2WK8F@28221|Deltaproteobacteria,2MJU9@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
XH1_k127_4153763_4	1235797.C816_00034	2.397e-91	313.0	COG1035@1|root,COG1035@2|Bacteria	2|Bacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus	frhB	-	1.12.98.1,1.3.7.13	ko:K00441,ko:K21231	ko00680,ko00860,ko01100,ko01120,map00680,map00860,map01100,map01120	-	R03025,R11519	RC01376,RC02628	ko00000,ko00001,ko01000	-	-	-	FrhB_FdhB_C,FrhB_FdhB_N
XH1_k127_4153763_8	439235.Dalk_2980	9.258e-70	241.0	COG1014@1|root,COG1014@2|Bacteria,1RJBM@1224|Proteobacteria,42T3A@68525|delta/epsilon subdivisions,2WPV1@28221|Deltaproteobacteria,2MNCY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	indolepyruvate ferredoxin oxidoreductase, beta subunit	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
XH1_k127_4153763_1	439235.Dalk_2981	2.1e-281	877.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42Q2C@68525|delta/epsilon subdivisions,2WKNN@28221|Deltaproteobacteria,2MN1W@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
XH1_k127_4153763_9	439235.Dalk_0830	1.59e-60	216.0	COG1309@1|root,COG1309@2|Bacteria,1N6R3@1224|Proteobacteria,42N4M@68525|delta/epsilon subdivisions,2WQ5F@28221|Deltaproteobacteria,2MKF8@213118|Desulfobacterales	28221|Deltaproteobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
XH1_k127_4153763_13	269799.Gmet_2972	9.374e-10	59.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42VQB@68525|delta/epsilon subdivisions,2WRF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
XH1_k127_4153763_0	56780.SYN_00533	0.0	1054.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,2MQAY@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	ccaA	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
XH1_k127_4153763_5	1182590.BN5_02949	1.467e-84	298.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1YCS9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerD	GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
XH1_k127_4153763_14	641491.DND132_2960	8.002e-06	56.0	COG0457@1|root,COG0457@2|Bacteria,1PDTX@1224|Proteobacteria,42RK5@68525|delta/epsilon subdivisions,2WNZC@28221|Deltaproteobacteria,2M93P@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
XH1_k127_4153763_3	1121441.AUCX01000020_gene589	3.552e-109	375.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2M7QR@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM cell wall hydrolase autolysin	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
XH1_k127_4153763_11	35841.BT1A1_0071	2.678e-34	141.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,1ZBQ0@1386|Bacillus	91061|Bacilli	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
XH1_k127_4153763_2	398512.JQKC01000012_gene246	7.545e-114	373.0	COG1878@1|root,COG1878@2|Bacteria,1USBQ@1239|Firmicutes,249A8@186801|Clostridia,3WMD2@541000|Ruminococcaceae	186801|Clostridia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
XH1_k127_4153763_12	1123371.ATXH01000003_gene1879	2.969e-27	114.0	COG0718@1|root,COG0718@2|Bacteria,2GHY9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
XH1_k127_4153763_10	335543.Sfum_2791	3.026e-59	212.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2WNCH@28221|Deltaproteobacteria,2MRIN@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
XH1_k127_4153763_7	1167006.UWK_00025	1.348e-75	263.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2MJDX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
XH1_k127_4159584_0	439235.Dalk_0853	4.533e-192	610.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MIAR@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
XH1_k127_419010_0	886293.Sinac_0692	5.73e-63	232.0	COG1404@1|root,COG1404@2|Bacteria,2IY4U@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
XH1_k127_419010_1	926692.AZYG01000053_gene1796	1.093e-42	168.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3WAFX@53433|Halanaerobiales	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
XH1_k127_419010_2	742741.HMPREF9475_03994	6.986e-30	125.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,21XEQ@1506553|Lachnoclostridium	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
XH1_k127_4192746_2	316067.Geob_2074	6.516e-30	120.0	COG1569@1|root,COG1569@2|Bacteria,1QSUM@1224|Proteobacteria,42WJR@68525|delta/epsilon subdivisions,2WRT9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
XH1_k127_4192746_3	665959.HMPREF1013_02573	6.415e-21	106.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,1ZBZE@1386|Bacillus	91061|Bacilli	E	COG0006 Xaa-Pro aminopeptidase	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
XH1_k127_4192746_0	96561.Dole_1611	2.998e-72	250.0	292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,42RFG@68525|delta/epsilon subdivisions,2WPKN@28221|Deltaproteobacteria,2MK0P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
XH1_k127_4192746_1	1487953.JMKF01000065_gene4581	7.108e-61	220.0	COG1216@1|root,COG3222@1|root,COG1216@2|Bacteria,COG3222@2|Bacteria,1G0X3@1117|Cyanobacteria,1HHXX@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064,Glycos_transf_2
XH1_k127_4204739_1	1265505.ATUG01000001_gene4653	1.911e-57	218.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PKS@68525|delta/epsilon subdivisions,2WJBK@28221|Deltaproteobacteria,2MHTB@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
XH1_k127_4204739_0	153721.MYP_3405	2.781e-158	513.0	COG0415@1|root,COG0415@2|Bacteria	2|Bacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
XH1_k127_4228008_15	502025.Hoch_2991	5.015e-37	141.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,42UN5@68525|delta/epsilon subdivisions,2WQU9@28221|Deltaproteobacteria,2YXHW@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
XH1_k127_4228008_17	56780.SYN_02386	1.396e-14	79.0	COG3809@1|root,COG3809@2|Bacteria,1N6ZY@1224|Proteobacteria,42VNA@68525|delta/epsilon subdivisions,2WRKK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
XH1_k127_4228008_7	926569.ANT_21990	2.037e-90	306.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
XH1_k127_4228008_13	335543.Sfum_2418	3.34e-49	187.0	COG0308@1|root,COG0308@2|Bacteria,1NJK3@1224|Proteobacteria,42Y4Q@68525|delta/epsilon subdivisions,2WTET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
XH1_k127_4228008_3	1146883.BLASA_2975	5.364e-100	334.0	COG1234@1|root,COG1234@2|Bacteria,2GJT2@201174|Actinobacteria	201174|Actinobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
XH1_k127_4228008_10	1265505.ATUG01000002_gene980	4.005e-62	218.0	COG2030@1|root,COG2030@2|Bacteria,1N4UG@1224|Proteobacteria,430GB@68525|delta/epsilon subdivisions,2WW0S@28221|Deltaproteobacteria,2MNJV@213118|Desulfobacterales	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
XH1_k127_4228008_16	198214.SF3196	6.004e-18	87.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	endonuclease containing a URI domain	yhbQ	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
XH1_k127_4228008_14	864069.MicloDRAFT_00020330	1.173e-37	146.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2U9M7@28211|Alphaproteobacteria,1JUJ6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Class I peptide chain release factor	MA20_05665	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
XH1_k127_4228008_6	1304885.AUEY01000085_gene2475	8.625e-92	308.0	COG1024@1|root,COG1024@2|Bacteria,1N2V7@1224|Proteobacteria,42UXR@68525|delta/epsilon subdivisions,2WQCT@28221|Deltaproteobacteria,2MI0D@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
XH1_k127_4228008_0	404380.Gbem_3948	1.012e-147	480.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42PV5@68525|delta/epsilon subdivisions,2WIKH@28221|Deltaproteobacteria,43UC2@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	PFAM multi antimicrobial extrusion protein MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
XH1_k127_4228008_2	1121405.dsmv_0829	3.991e-101	338.0	COG1397@1|root,COG1397@2|Bacteria,1RA82@1224|Proteobacteria,42QPD@68525|delta/epsilon subdivisions,2WMNN@28221|Deltaproteobacteria,2MJI9@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
XH1_k127_4228008_12	439235.Dalk_2819	3.759e-51	190.0	2BZTZ@1|root,2ZVGQ@2|Bacteria,1PAKI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4228008_9	1121403.AUCV01000033_gene3654	2.913e-63	224.0	COG1280@1|root,COG1280@2|Bacteria,1RJBR@1224|Proteobacteria,42T9G@68525|delta/epsilon subdivisions,2WP76@28221|Deltaproteobacteria,2MKPW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
XH1_k127_4228008_11	518766.Rmar_0656	8.389e-57	202.0	COG0252@1|root,COG0252@2|Bacteria,4NRB3@976|Bacteroidetes	976|Bacteroidetes	EJ	GlutRNAGln amidotransferase subunit D	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
XH1_k127_4228008_8	1205680.CAKO01000038_gene1502	5.434e-64	232.0	COG0400@1|root,COG0400@2|Bacteria,1P51S@1224|Proteobacteria,2TT0Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
XH1_k127_4228008_4	1121405.dsmv_1960	9.409e-98	334.0	COG4866@1|root,COG4866@2|Bacteria,1RIUZ@1224|Proteobacteria,42P4H@68525|delta/epsilon subdivisions,2WPMI@28221|Deltaproteobacteria,2MM47@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
XH1_k127_4228008_5	439235.Dalk_2961	1.693e-92	314.0	COG1639@1|root,COG1639@2|Bacteria,1RBFE@1224|Proteobacteria,42QRK@68525|delta/epsilon subdivisions,2WMYG@28221|Deltaproteobacteria,2MJHI@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,zinc_ribbon_4
XH1_k127_4228008_19	1259795.ARJK01000002_gene163	3.364e-11	69.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,24HH7@186801|Clostridia,42GPB@68295|Thermoanaerobacterales	186801|Clostridia	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
XH1_k127_4228008_18	1123400.KB904746_gene1309	2.251e-12	68.0	2E4SV@1|root,32ZM7@2|Bacteria,1N8VN@1224|Proteobacteria,1SAKS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
XH1_k127_4234341_0	96561.Dole_3113	1.59e-147	486.0	COG0457@1|root,COG5305@1|root,COG0457@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_4272165_3	1280947.HY30_07305	9.037e-13	73.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,43W88@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
XH1_k127_4272165_2	891968.Anamo_1293	6.823e-45	172.0	COG1414@1|root,COG1414@2|Bacteria,3TBG0@508458|Synergistetes	508458|Synergistetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
XH1_k127_4272165_0	457415.HMPREF1006_02045	2.997e-158	514.0	COG1593@1|root,COG1593@2|Bacteria,3TA8I@508458|Synergistetes	508458|Synergistetes	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
XH1_k127_4272165_1	2754.EH55_12560	6.281e-128	417.0	COG1638@1|root,COG1638@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctP
XH1_k127_4279904_1	868595.Desca_0183	7.644e-180	568.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,2607A@186807|Peptococcaceae	186801|Clostridia	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
XH1_k127_4279904_2	909663.KI867150_gene1087	6.332e-141	465.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675,ko:K09684	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,MASE1,PAS,PAS_3,PAS_4,PAS_9,Peripla_BP_3,Response_reg,dCache_2
XH1_k127_4279904_3	56780.SYN_02588	1.063e-93	313.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42N8J@68525|delta/epsilon subdivisions,2WK63@28221|Deltaproteobacteria,2MRGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
XH1_k127_4279904_0	56780.SYN_02382	9.911e-264	815.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2MR9X@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
XH1_k127_4279904_4	909663.KI867150_gene1083	1.169e-33	139.0	COG1693@1|root,COG1693@2|Bacteria,1RAC2@1224|Proteobacteria,42QW9@68525|delta/epsilon subdivisions,2WMZV@28221|Deltaproteobacteria,2MQWZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Ribonuclease R winged-helix domain	-	-	-	ko:K09720	-	-	-	-	ko00000,ko03000	-	-	-	DUF128,HTH_12
XH1_k127_428778_1	335543.Sfum_3877	5.346e-49	181.0	COG1595@1|root,COG1595@2|Bacteria,1Q4ZK@1224|Proteobacteria,42TZB@68525|delta/epsilon subdivisions,2WR1D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_428778_2	335543.Sfum_3879	1.661e-23	106.0	COG3678@1|root,COG3678@2|Bacteria,1P50Y@1224|Proteobacteria,43317@68525|delta/epsilon subdivisions,2WXNH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
XH1_k127_428778_0	589865.DaAHT2_2391	3.141e-70	244.0	28P1J@1|root,2ZBXX@2|Bacteria,1REYC@1224|Proteobacteria,42RM0@68525|delta/epsilon subdivisions,2WNN9@28221|Deltaproteobacteria,2MJS1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyrimidine dimer DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,Pyr_excise
XH1_k127_4312458_0	269799.Gmet_3311	5.329e-102	340.0	COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,42PGN@68525|delta/epsilon subdivisions,2WKIA@28221|Deltaproteobacteria,43VK7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	tssK	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
XH1_k127_4312458_1	1265505.ATUG01000001_gene4577	8.491e-46	171.0	COG3521@1|root,COG3521@2|Bacteria,1N5FF@1224|Proteobacteria,42UFY@68525|delta/epsilon subdivisions,2WQTG@28221|Deltaproteobacteria,2MNUB@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113	tssJ	-	-	-	-	-	-	-	-	-	-	-	T6SS-SciN
XH1_k127_4312458_2	1265505.ATUG01000001_gene4576	5.792e-38	149.0	2CD95@1|root,32TF9@2|Bacteria,1N4QU@1224|Proteobacteria,42UX1@68525|delta/epsilon subdivisions,2WPZB@28221|Deltaproteobacteria,2MKR2@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4326705_6	1304885.AUEY01000016_gene3066	1.402e-42	162.0	COG0834@1|root,COG0834@2|Bacteria,1R4SQ@1224|Proteobacteria,42T9E@68525|delta/epsilon subdivisions,2WPWJ@28221|Deltaproteobacteria,2MNPF@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
XH1_k127_4326705_3	439235.Dalk_2054	2.174e-138	445.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42N5A@68525|delta/epsilon subdivisions,2WKKI@28221|Deltaproteobacteria,2MIZW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA ATPase domain	clpB1	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
XH1_k127_4326705_2	439235.Dalk_2055	2.009e-140	460.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,1MUHH@1224|Proteobacteria,42QBK@68525|delta/epsilon subdivisions,2WITZ@28221|Deltaproteobacteria,2MHM0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
XH1_k127_4326705_4	439235.Dalk_4842	9.503e-62	231.0	COG1960@1|root,COG1960@2|Bacteria,1N4CR@1224|Proteobacteria,42UG2@68525|delta/epsilon subdivisions,2WR36@28221|Deltaproteobacteria,2MKI1@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_4326705_5	439235.Dalk_2630	3.414e-60	214.0	COG1309@1|root,COG1309@2|Bacteria,1Q9AV@1224|Proteobacteria,42ZTC@68525|delta/epsilon subdivisions,2WUZ6@28221|Deltaproteobacteria,2MN9P@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
XH1_k127_4326705_1	439235.Dalk_4525	1.358e-176	561.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2WJQW@28221|Deltaproteobacteria,2MHRC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
XH1_k127_4326705_0	96561.Dole_2975	5.828e-208	663.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria,2MK4Y@213118|Desulfobacterales	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
XH1_k127_4347178_0	443143.GM18_2214	8.523e-138	455.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,43TCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
XH1_k127_4347178_1	1125863.JAFN01000001_gene1870	1.435e-129	425.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
XH1_k127_4347178_3	644282.Deba_0830	2.653e-31	130.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2WQ4F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
XH1_k127_4347178_4	642492.Clole_2946	1.574e-16	87.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
XH1_k127_4347178_2	207559.Dde_2638	3.721e-58	207.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2M933@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
XH1_k127_436967_2	795359.TOPB45_0926	7.61e-37	147.0	COG2165@1|root,COG2165@2|Bacteria,2GI1E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
XH1_k127_436967_0	795359.TOPB45_0916	1.19e-159	520.0	COG2804@1|root,COG2804@2|Bacteria,2GHDT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
XH1_k127_436967_1	667014.Thein_1886	2.163e-69	251.0	COG1459@1|root,COG1459@2|Bacteria,2GH3B@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
XH1_k127_436967_5	1198452.Jab_2c02530	2.784e-14	81.0	COG2165@1|root,COG2165@2|Bacteria,1RHE1@1224|Proteobacteria,2VSJ6@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
XH1_k127_436967_3	694431.DESACE_01345	5.034e-21	104.0	COG4796@1|root,COG4796@2|Bacteria,1QUXY@1224|Proteobacteria,43D2W@68525|delta/epsilon subdivisions,2WNS3@28221|Deltaproteobacteria,2M6MR@213113|Desulfurellales	28221|Deltaproteobacteria	U	Bacterial type II and III secretion system protein	-	-	-	ko:K12282	-	-	-	-	ko00000,ko02044	-	-	-	Secretin
XH1_k127_440112_1	768704.Desmer_2486	6.659e-55	195.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
XH1_k127_440112_0	756499.Desde_2311	9.798e-179	585.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia,260K6@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
XH1_k127_440112_2	706587.Desti_3420	2.98e-42	158.0	COG0438@1|root,COG0662@1|root,COG0438@2|Bacteria,COG0662@2|Bacteria,1MWSZ@1224|Proteobacteria,42NYZ@68525|delta/epsilon subdivisions,2WK9U@28221|Deltaproteobacteria,2MQ7Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,MannoseP_isomer
XH1_k127_440112_4	293826.Amet_0774	1.025e-05	54.0	2BYUV@1|root,307Y4@2|Bacteria,1V64G@1239|Firmicutes,24K9A@186801|Clostridia,36N5G@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_440112_3	215803.DB30_1036	3.444e-15	87.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,1R6WM@1224|Proteobacteria,43AGT@68525|delta/epsilon subdivisions,2X5WS@28221|Deltaproteobacteria,2YVSQ@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_16
XH1_k127_441889_11	338966.Ppro_0398	5.43e-28	123.0	COG2202@1|root,COG2203@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,43UJP@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_3,Sigma54_activat
XH1_k127_441889_16	1120963.KB894491_gene1107	1.072e-05	49.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_441889_6	717231.Flexsi_0373	1.382e-57	205.0	2DMID@1|root,32RSF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii,DUF2204
XH1_k127_441889_1	1232410.KI421426_gene1487	1.397e-191	615.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,43T0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Pyruvate kinase, barrel domain	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
XH1_k127_441889_0	338966.Ppro_3415	3.881e-292	919.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,43T5A@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF3417)	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
XH1_k127_441889_13	944479.JQLX01000012_gene1057	5.033e-20	99.0	COG1729@1|root,COG1729@2|Bacteria,1Q17D@1224|Proteobacteria,42WQ5@68525|delta/epsilon subdivisions,2WRU2@28221|Deltaproteobacteria,2M75T@213113|Desulfurellales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_6
XH1_k127_441889_9	1232410.KI421422_gene2003	2.145e-42	163.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,43UVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM OmpA MotB domain protein	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
XH1_k127_441889_5	502025.Hoch_0133	5.929e-58	220.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
XH1_k127_441889_17	1121406.JAEX01000001_gene481	0.0003293	52.0	COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,42XAV@68525|delta/epsilon subdivisions,2WSJJ@28221|Deltaproteobacteria,2M7R0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_2
XH1_k127_441889_12	1232437.KL662039_gene2067	1.058e-27	119.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,2MKKC@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
XH1_k127_441889_8	177439.DP2409	1.446e-42	165.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2WNQ4@28221|Deltaproteobacteria,2MHWF@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	tolQ	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
XH1_k127_441889_7	1121441.AUCX01000010_gene104	3.143e-52	197.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2M8UQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_3_2
XH1_k127_441889_10	697281.Mahau_1599	2.458e-32	130.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,42GA2@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
XH1_k127_441889_4	926569.ANT_23310	6.243e-77	271.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
XH1_k127_441889_15	933262.AXAM01000013_gene1281	3.773e-07	60.0	2DREI@1|root,33BE1@2|Bacteria,1QWMW@1224|Proteobacteria,43BST@68525|delta/epsilon subdivisions,2X73M@28221|Deltaproteobacteria,2MMBB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_441889_2	316067.Geob_0774	3.34e-129	432.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
XH1_k127_441889_3	395961.Cyan7425_0619	1.547e-116	391.0	COG0769@1|root,COG0769@2|Bacteria,1G0HH@1117|Cyanobacteria,3KG4F@43988|Cyanothece	1117|Cyanobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
XH1_k127_441889_14	401526.TcarDRAFT_0187	1.128e-12	71.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4H1XX@909932|Negativicutes	909932|Negativicutes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
XH1_k127_4424115_3	637389.Acaty_c1407	2.069e-24	107.0	COG4902@1|root,COG4902@2|Bacteria,1RHUF@1224|Proteobacteria,1SAI2@1236|Gammaproteobacteria,2NCXE@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
XH1_k127_4424115_1	1167006.UWK_01521	1.144e-35	150.0	28WPZ@1|root,2ZIPP@2|Bacteria,1RA62@1224|Proteobacteria,42QRN@68525|delta/epsilon subdivisions,2WN0T@28221|Deltaproteobacteria,2MJGA@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4424115_4	1167006.UWK_01522	1.575e-19	92.0	2ENER@1|root,33G27@2|Bacteria,1NGAB@1224|Proteobacteria,42WZZ@68525|delta/epsilon subdivisions,2WTCF@28221|Deltaproteobacteria,2MMEF@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4424115_0	1167006.UWK_01523	3.007e-40	156.0	COG0296@1|root,COG0296@2|Bacteria,1RGK6@1224|Proteobacteria,42S24@68525|delta/epsilon subdivisions,2WNU4@28221|Deltaproteobacteria,2MJS2@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
XH1_k127_4424115_2	1167006.UWK_01524	2.256e-34	137.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2WPA8@28221|Deltaproteobacteria,2MKBP@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_4428074_7	1121472.AQWN01000002_gene2167	8.804e-63	226.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,260HN@186807|Peptococcaceae	186801|Clostridia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	nit	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
XH1_k127_4428074_6	1121406.JAEX01000003_gene1572	6.026e-85	287.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2M854@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM ABC transporter related	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
XH1_k127_4428074_8	247490.KSU1_D0738	1.87e-32	131.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
XH1_k127_4428074_9	716544.wcw_1461	1.864e-30	125.0	COG1186@1|root,COG1186@2|Bacteria,2JH63@204428|Chlamydiae	204428|Chlamydiae	J	RF-1 domain	prfA3	-	-	-	-	-	-	-	-	-	-	-	RF-1
XH1_k127_4428074_5	443143.GM18_2163	1.233e-89	302.0	COG2518@1|root,COG2518@2|Bacteria,1RC4G@1224|Proteobacteria,43E9Z@68525|delta/epsilon subdivisions,2X7S5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
XH1_k127_4428074_3	338966.Ppro_1407	2.004e-103	363.0	COG0515@1|root,COG0515@2|Bacteria,1N9V2@1224|Proteobacteria,42Q0B@68525|delta/epsilon subdivisions,2WJXJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4428074_2	56780.SYN_02213	2.94e-138	475.0	COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1R891@1224|Proteobacteria,42P2C@68525|delta/epsilon subdivisions,2WJZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
XH1_k127_4428074_4	56780.SYN_03357	1.22e-89	305.0	COG0679@1|root,COG0679@2|Bacteria	2|Bacteria	S	auxin-activated signaling pathway	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
XH1_k127_4428074_0	56780.SYN_02214	3.333e-188	597.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_4428074_1	56780.SYN_02215	4.594e-142	474.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_9
XH1_k127_4428074_10	1006000.GKAS_03748	1.934e-05	53.0	COG3678@1|root,COG3678@2|Bacteria,1RI83@1224|Proteobacteria,1S6TF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NPTU	Binds zinc. Could be an important component of the zinc- balancing mechanism	zraP	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897	-	ko:K07803	ko02020,map02020	-	-	-	ko00000,ko00001,ko03110	-	-	-	Metal_resist
XH1_k127_4441089_0	944479.JQLX01000018_gene191	2.823e-132	443.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2M7IE@213113|Desulfurellales	28221|Deltaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
XH1_k127_4441089_2	671143.DAMO_0811	3.109e-18	89.0	COG0721@1|root,COG0721@2|Bacteria,2NPXC@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
XH1_k127_4441089_1	795359.TOPB45_0597	6.186e-51	185.0	COG0154@1|root,COG0154@2|Bacteria,2GHH3@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
XH1_k127_4461130_0	1123371.ATXH01000006_gene873	1.982e-136	441.0	COG0154@1|root,COG0154@2|Bacteria,2GHH3@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
XH1_k127_4461130_1	880072.Desac_0997	1.329e-116	386.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2MQ8D@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
XH1_k127_4535562_2	56780.SYN_03850	3.31e-30	125.0	2E20Q@1|root,32X8P@2|Bacteria,1NF7J@1224|Proteobacteria,42V60@68525|delta/epsilon subdivisions,2WRJ8@28221|Deltaproteobacteria,2MSE9@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4535562_1	1121440.AUMA01000003_gene3093	2.607e-65	237.0	COG0697@1|root,COG0697@2|Bacteria,1NFUD@1224|Proteobacteria,42WQ8@68525|delta/epsilon subdivisions,2WRZN@28221|Deltaproteobacteria,2MB1G@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
XH1_k127_4535562_0	439235.Dalk_2789	2.307e-215	681.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2MIKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
XH1_k127_4546089_3	96561.Dole_1608	4.92e-21	93.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2MJ4H@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
XH1_k127_4546089_2	760568.Desku_2713	7.807e-52	192.0	COG5012@1|root,COG5012@2|Bacteria,1V33W@1239|Firmicutes,24J77@186801|Clostridia,266X4@186807|Peptococcaceae	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
XH1_k127_4546089_1	1009370.ALO_15132	2.699e-69	250.0	COG0407@1|root,COG0407@2|Bacteria,1TPQ6@1239|Firmicutes,4H97I@909932|Negativicutes	1239|Firmicutes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
XH1_k127_4546089_0	439235.Dalk_2036	2.808e-253	790.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MIAR@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
XH1_k127_4550016_4	931276.Cspa_c06780	1.992e-46	168.0	COG2159@1|root,COG2159@2|Bacteria,1V0UC@1239|Firmicutes,25CIB@186801|Clostridia	186801|Clostridia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
XH1_k127_4550016_2	768670.Calni_0340	3.356e-81	286.0	COG2067@1|root,COG2067@2|Bacteria,2GFPR@200930|Deferribacteres	200930|Deferribacteres	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
XH1_k127_4550016_1	96561.Dole_1608	3.372e-90	306.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2MJ4H@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
XH1_k127_4550016_5	87626.PTD2_04958	6.045e-05	46.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4550016_0	555779.Dthio_PD3431	2.461e-141	460.0	COG0406@1|root,COG0406@2|Bacteria,1R4II@1224|Proteobacteria,42Q0D@68525|delta/epsilon subdivisions,2WKA0@28221|Deltaproteobacteria,2M9WS@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	6PF2K,His_Phos_1
XH1_k127_4550016_3	644282.Deba_1392	4.267e-77	270.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1R7IR@1224|Proteobacteria,42MT7@68525|delta/epsilon subdivisions,2WITW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_1,TPR_14,TPR_2,TPR_8
XH1_k127_4553661_2	96561.Dole_0816	2.145e-58	210.0	COG1309@1|root,COG1309@2|Bacteria,1MZE6@1224|Proteobacteria,4318R@68525|delta/epsilon subdivisions,2WX5H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_4553661_1	247639.MGP2080_11333	3.116e-88	299.0	COG4689@1|root,COG4689@2|Bacteria,1NDQG@1224|Proteobacteria,1SZYJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	acetoacetate decarboxylase	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
XH1_k127_4553661_0	96561.Dole_0818	1.395e-115	385.0	COG1960@1|root,COG1960@2|Bacteria,1P7WH@1224|Proteobacteria,42QKR@68525|delta/epsilon subdivisions,2WM93@28221|Deltaproteobacteria,2MJM8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_4553661_3	2325.TKV_c01960	1.557e-08	57.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,42EN0@68295|Thermoanaerobacterales	186801|Clostridia	P	Ferrous iron transport protein B	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
XH1_k127_457016_5	1242864.D187_001763	7.483e-49	178.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2YU45@29|Myxococcales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
XH1_k127_457016_4	207954.MED92_16905	2.551e-55	206.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1XH4Y@135619|Oceanospirillales	135619|Oceanospirillales	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	ParA
XH1_k127_457016_2	760568.Desku_2677	7.721e-98	330.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,260P7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
XH1_k127_457016_1	1382306.JNIM01000001_gene602	1.109e-108	363.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	2|Bacteria	C	PFAM acyl-CoA dehydrogenase domain protein	ivd	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_457016_0	1333998.M2A_1970	1.427e-156	512.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,4BPQ9@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
XH1_k127_457016_3	56780.SYN_02176	1.329e-94	319.0	COG1032@1|root,COG1032@2|Bacteria,1R4XI@1224|Proteobacteria,42NPM@68525|delta/epsilon subdivisions,2WJK2@28221|Deltaproteobacteria,2MQ6Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
XH1_k127_4574304_2	335543.Sfum_2795	1.865e-88	297.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MQUN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase beta subunit	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
XH1_k127_4574304_0	706587.Desti_2934	4.857e-167	538.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2MQ7R@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
XH1_k127_4574304_6	90814.KL370892_gene2304	3.859e-37	160.0	COG5002@1|root,COG5002@2|Bacteria,1QVXJ@1224|Proteobacteria,1T2NA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
XH1_k127_4574304_1	1125863.JAFN01000001_gene746	2.459e-140	460.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Y98@68525|delta/epsilon subdivisions,2WTXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_4574304_5	1144275.COCOR_02982	1.93e-38	151.0	COG1596@1|root,COG1596@2|Bacteria,1N6I6@1224|Proteobacteria,42UGK@68525|delta/epsilon subdivisions,2WQTF@28221|Deltaproteobacteria,2YVVS@29|Myxococcales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
XH1_k127_4574304_3	933262.AXAM01000037_gene884	1.107e-77	280.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,42M2D@68525|delta/epsilon subdivisions,2WJU6@28221|Deltaproteobacteria,2MIV6@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
XH1_k127_4574304_4	589865.DaAHT2_0464	7.5e-66	238.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,2MIMN@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Peptidoglycan-binding domain 1 protein	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
XH1_k127_45797_3	1167006.UWK_00611	1.021e-13	75.0	COG0607@1|root,COG0607@2|Bacteria,1P5S7@1224|Proteobacteria,432U2@68525|delta/epsilon subdivisions,2WXWU@28221|Deltaproteobacteria,2MPCG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_45797_1	644282.Deba_2975	4.562e-110	376.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,43CB2@68525|delta/epsilon subdivisions,2X7MH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
XH1_k127_45797_2	1121405.dsmv_0026	2.391e-68	235.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2MJZR@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
XH1_k127_45797_0	401526.TcarDRAFT_1997	9.651e-119	390.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4H20U@909932|Negativicutes	1239|Firmicutes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
XH1_k127_4599666_1	589873.EP13_14560	2.707e-30	123.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4650W@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	prsR	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_4599666_0	933262.AXAM01000033_gene1634	1.58e-79	291.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,42PTN@68525|delta/epsilon subdivisions,2WKBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c
XH1_k127_4616148_1	314278.NB231_03015	2.137e-82	288.0	2C40F@1|root,33WUG@2|Bacteria,1NWBW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4616148_0	1304885.AUEY01000005_gene892	1.823e-95	323.0	COG0598@1|root,COG0598@2|Bacteria,1RGGI@1224|Proteobacteria,42UX4@68525|delta/epsilon subdivisions,2WQYH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Mg2 transporter protein CorA family protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
XH1_k127_4627139_0	335543.Sfum_0484	2.232e-66	231.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2WMNR@28221|Deltaproteobacteria,2MRNQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
XH1_k127_4627139_3	1167006.UWK_03012	1.08e-26	126.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2MIXJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
XH1_k127_4627139_2	1415779.JOMH01000001_gene2902	1.455e-27	129.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,1X6CY@135614|Xanthomonadales	135614|Xanthomonadales	NT	chemotaxis signal transduction protein	cheW1	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
XH1_k127_4627139_1	335543.Sfum_0123	4.69e-32	133.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,2MQQC@213462|Syntrophobacterales	28221|Deltaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
XH1_k127_4636812_4	1121440.AUMA01000011_gene2323	7.365e-42	157.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42NU8@68525|delta/epsilon subdivisions,2WM5F@28221|Deltaproteobacteria,2MA6U@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	TIGRFAM flagellar motor stator protein MotA	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
XH1_k127_4636812_2	1121440.AUMA01000011_gene2322	5.1e-62	224.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,42S6Q@68525|delta/epsilon subdivisions,2WNX0@28221|Deltaproteobacteria,2MA7U@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
XH1_k127_4636812_1	96561.Dole_0758	2.648e-92	307.0	COG1765@1|root,COG1765@2|Bacteria,1N1T3@1224|Proteobacteria,42UFR@68525|delta/epsilon subdivisions,2WQ83@28221|Deltaproteobacteria,2MMSD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
XH1_k127_4636812_3	748280.NH8B_0019	3.762e-45	166.0	COG0730@1|root,COG0730@2|Bacteria,1PYEK@1224|Proteobacteria,2W2DY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
XH1_k127_4636812_0	926569.ANT_28300	6.509e-113	372.0	COG2199@1|root,COG3706@2|Bacteria,2G64S@200795|Chloroflexi	200795|Chloroflexi	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
XH1_k127_4636812_5	555079.Toce_1493	2.162e-14	78.0	COG3543@1|root,COG3543@2|Bacteria,1VFVM@1239|Firmicutes,24R1N@186801|Clostridia,42GX4@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF1284)	-	-	-	ko:K09706	-	-	-	-	ko00000	-	-	-	DUF1284
XH1_k127_4643710_0	56780.SYN_02956	4.961e-161	522.0	COG2202@1|root,COG2203@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MR33@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	GAF,HTH_8,PAS,PAS_3,PAS_4,PAS_9,Sigma54_activat
XH1_k127_4643710_2	1232410.KI421421_gene3332	6.829e-20	94.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42TXG@68525|delta/epsilon subdivisions,2WQI4@28221|Deltaproteobacteria,43W20@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
XH1_k127_4643710_1	1395516.PMO01_14390	2.603e-141	465.0	COG5164@1|root,COG5164@2|Bacteria,1MX1Z@1224|Proteobacteria,1T5GM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4658124_3	1415756.JQMY01000001_gene3662	1.433e-27	124.0	COG0451@1|root,COG0451@2|Bacteria,1NXWA@1224|Proteobacteria,2TVJJ@28211|Alphaproteobacteria,2PCSN@252301|Oceanicola	28211|Alphaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,SPW,VKOR
XH1_k127_4658124_2	272134.KB731324_gene2648	1.246e-39	158.0	COG0300@1|root,COG0300@2|Bacteria,1G2GZ@1117|Cyanobacteria,1H7D2@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
XH1_k127_4658124_0	338963.Pcar_1397	3.129e-170	564.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,43TNZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Glycine radical	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
XH1_k127_4658124_1	439235.Dalk_2103	1.744e-55	196.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,42S03@68525|delta/epsilon subdivisions,2WNW5@28221|Deltaproteobacteria,2MQ1F@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
XH1_k127_4666225_0	439235.Dalk_1142	1.589e-98	340.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
XH1_k127_4666225_1	314230.DSM3645_22084	8.208e-52	189.0	COG2008@1|root,COG2008@2|Bacteria,2IZ5U@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
XH1_k127_4703573_1	1444309.JAQG01000075_gene127	5.922e-83	283.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,4HBH3@91061|Bacilli,26RZT@186822|Paenibacillaceae	91061|Bacilli	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
XH1_k127_4703573_2	1226322.HMPREF1545_03924	1.27e-51	195.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,2N6BC@216572|Oscillospiraceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
XH1_k127_4703573_5	439235.Dalk_3936	3.51e-14	79.0	COG1371@1|root,COG1371@2|Bacteria,1NCP6@1224|Proteobacteria,42VQE@68525|delta/epsilon subdivisions,2WS6C@28221|Deltaproteobacteria,2MM59@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
XH1_k127_4703573_0	338963.Pcar_0019	1.099e-166	537.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,43SZD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
XH1_k127_4703573_4	383372.Rcas_1070	2.833e-29	126.0	COG1825@1|root,COG1825@2|Bacteria,2G6YX@200795|Chloroflexi,375RP@32061|Chloroflexia	32061|Chloroflexia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
XH1_k127_4703573_3	1121405.dsmv_2116	5.817e-33	131.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,2MK62@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
XH1_k127_4738274_0	1321786.HMPREF1992_01173	1.205e-71	258.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes	1239|Firmicutes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
XH1_k127_4738274_1	1304888.ATWF01000001_gene1012	1.778e-51	186.0	COG1945@1|root,COG1945@2|Bacteria,2GGDV@200930|Deferribacteres	200930|Deferribacteres	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	-	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
XH1_k127_4738274_2	1125863.JAFN01000001_gene465	4.435e-46	172.0	COG1396@1|root,COG1396@2|Bacteria,1RG9R@1224|Proteobacteria,42S0C@68525|delta/epsilon subdivisions,2WNYP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix transcriptional regulator PuuR, cupin domain-containing	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
XH1_k127_4763548_1	1121422.AUMW01000014_gene1313	4.296e-32	132.0	COG4739@1|root,COG4739@2|Bacteria	2|Bacteria	S	Uncharacterized protein containing a ferredoxin domain (DUF2148)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2148
XH1_k127_4763548_0	177437.HRM2_39920	1.332e-137	450.0	COG1960@1|root,COG1960@2|Bacteria,1P7WH@1224|Proteobacteria,42QKR@68525|delta/epsilon subdivisions,2WM93@28221|Deltaproteobacteria,2MJM8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_4763548_2	177437.HRM2_40000	6.841e-32	128.0	COG1454@1|root,COG1454@2|Bacteria,1NCF7@1224|Proteobacteria,42VM0@68525|delta/epsilon subdivisions,2WS5T@28221|Deltaproteobacteria,2MNUI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
XH1_k127_4766770_2	1121406.JAEX01000005_gene3071	4.988e-78	265.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2M90H@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
XH1_k127_4766770_4	1304883.KI912532_gene1632	3.847e-45	177.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,2KWGX@206389|Rhodocyclales	206389|Rhodocyclales	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
XH1_k127_4766770_9	1045855.DSC_00480	0.0003087	50.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1X4KE@135614|Xanthomonadales	135614|Xanthomonadales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
XH1_k127_4766770_8	1353537.TP2_05890	2.267e-15	82.0	COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria,2XNCP@285107|Thioclava	28211|Alphaproteobacteria	S	OstA-like protein	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
XH1_k127_4766770_1	760192.Halhy_2557	1.081e-84	288.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1IQQ1@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
XH1_k127_4766770_0	316067.Geob_2280	9.104e-133	437.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43UH4@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
XH1_k127_4766770_6	635013.TherJR_2776	1.068e-38	152.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,261QJ@186807|Peptococcaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
XH1_k127_4766770_5	378806.STAUR_1619	2.287e-41	157.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2YVHR@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
XH1_k127_4766770_3	1232410.KI421424_gene1634	2.838e-60	225.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,42P6A@68525|delta/epsilon subdivisions,2WJZ4@28221|Deltaproteobacteria,43U4U@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,dCache_1
XH1_k127_4766770_7	56780.SYN_02965	7.901e-33	132.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42UFU@68525|delta/epsilon subdivisions,2WR59@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
XH1_k127_4773989_0	1125863.JAFN01000001_gene765	1.442e-87	295.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
XH1_k127_4773989_1	443144.GM21_3395	3.648e-78	273.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,43TN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
XH1_k127_4773989_2	1121440.AUMA01000007_gene1247	6.488e-39	154.0	2CA4A@1|root,32RQK@2|Bacteria,1RE4A@1224|Proteobacteria,42RRI@68525|delta/epsilon subdivisions,2WND4@28221|Deltaproteobacteria,2MBTY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
XH1_k127_4830243_1	635013.TherJR_0525	3.736e-96	333.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,260IW@186807|Peptococcaceae	186801|Clostridia	C	PFAM Acetyl-CoA hydrolase transferase	cat	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
XH1_k127_4830243_0	56780.SYN_02629	7.618e-115	384.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,42PJV@68525|delta/epsilon subdivisions,2WKRG@28221|Deltaproteobacteria,2MS2C@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
XH1_k127_4830243_3	1499967.BAYZ01000118_gene3297	0.0002529	52.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
XH1_k127_4830243_2	1458275.AZ34_12815	3.726e-40	154.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2VJW8@28216|Betaproteobacteria,4AATS@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
XH1_k127_4834181_5	1304284.L21TH_0881	6.826e-38	147.0	COG1578@1|root,COG1578@2|Bacteria,1UURD@1239|Firmicutes,2492C@186801|Clostridia,36GFY@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
XH1_k127_4834181_6	488538.SAR116_1690	3.448e-05	53.0	COG0741@1|root,COG0741@2|Bacteria,1Q1W2@1224|Proteobacteria,2V9H9@28211|Alphaproteobacteria,4BSPX@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
XH1_k127_4834181_4	1379698.RBG1_1C00001G0669	3.414e-41	163.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	Peptidase_M56
XH1_k127_4834181_0	926569.ANT_17330	0.0	1125.0	COG0366@1|root,COG0366@2|Bacteria,2G7SV@200795|Chloroflexi	200795|Chloroflexi	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
XH1_k127_4834181_1	96561.Dole_2113	1.291e-218	686.0	COG0034@1|root,COG0034@2|Bacteria,1R7JX@1224|Proteobacteria,42MAC@68525|delta/epsilon subdivisions,2WKFD@28221|Deltaproteobacteria,2MIUW@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Glutamine amidotransferase domain	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
XH1_k127_4834181_2	1304885.AUEY01000014_gene3338	9.241e-197	625.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2MJ7G@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
XH1_k127_4834181_3	880072.Desac_2488	3.313e-67	239.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMP4@28221|Deltaproteobacteria,2MQD5@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
XH1_k127_484666_3	398512.JQKC01000008_gene950	1.935e-26	113.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,3WSMG@541000|Ruminococcaceae	186801|Clostridia	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_484666_2	645991.Sgly_0217	2.393e-31	129.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,2629P@186807|Peptococcaceae	186801|Clostridia	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
XH1_k127_484666_0	706587.Desti_3075	5.307e-82	279.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,42NS5@68525|delta/epsilon subdivisions,2WNQ5@28221|Deltaproteobacteria,2MQFJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
XH1_k127_484666_1	335543.Sfum_0055	3.777e-78	269.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2MREE@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
XH1_k127_4860697_14	78245.Xaut_1700	5.51e-05	49.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,3EY7Y@335928|Xanthobacteraceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
XH1_k127_4860697_0	909663.KI867150_gene908	1.685e-215	702.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,42M50@68525|delta/epsilon subdivisions,2WIP4@28221|Deltaproteobacteria,2MQYM@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
XH1_k127_4860697_3	335543.Sfum_3692	9.791e-115	376.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria,2MQ9U@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
XH1_k127_4860697_5	706587.Desti_0100	6.297e-98	332.0	COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,42Y4B@68525|delta/epsilon subdivisions,2WSY8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PHB de-polymerase C-terminus	-	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	PHB_depo_C
XH1_k127_4860697_8	933262.AXAM01000004_gene2368	3.323e-41	160.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,42WB9@68525|delta/epsilon subdivisions,2WQ0S@28221|Deltaproteobacteria,2MKS1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PHB/PHA accumulation regulator DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
XH1_k127_4860697_11	1121405.dsmv_3713	8.226e-19	89.0	2E3F6@1|root,32YE2@2|Bacteria,1NDBB@1224|Proteobacteria,42WNV@68525|delta/epsilon subdivisions,2WRV2@28221|Deltaproteobacteria,2MKYS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4860697_12	1121405.dsmv_3713	2.221e-18	88.0	2E3F6@1|root,32YE2@2|Bacteria,1NDBB@1224|Proteobacteria,42WNV@68525|delta/epsilon subdivisions,2WRV2@28221|Deltaproteobacteria,2MKYS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4860697_9	1121405.dsmv_3606	8.126e-23	100.0	2E3F6@1|root,32YE2@2|Bacteria,1NDBB@1224|Proteobacteria,42WNV@68525|delta/epsilon subdivisions,2WRV2@28221|Deltaproteobacteria,2MKYS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4860697_1	933262.AXAM01000004_gene2371	8.314e-200	638.0	28I62@1|root,2Z896@2|Bacteria,1MWB8@1224|Proteobacteria,42P7E@68525|delta/epsilon subdivisions,2WKM1@28221|Deltaproteobacteria,2MIBX@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4860697_10	1121405.dsmv_3711	1.149e-20	100.0	28YDZ@1|root,2ZK8G@2|Bacteria,1P7II@1224|Proteobacteria,4334F@68525|delta/epsilon subdivisions,2WY88@28221|Deltaproteobacteria,2MP69@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4860697_7	1121405.dsmv_1701	7.745e-58	205.0	COG2030@1|root,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,42SWX@68525|delta/epsilon subdivisions,2WPJ0@28221|Deltaproteobacteria,2MK5C@213118|Desulfobacterales	28221|Deltaproteobacteria	I	MaoC like domain	maoC	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
XH1_k127_4860697_4	1121405.dsmv_1700	3.255e-111	369.0	COG2203@1|root,COG2203@2|Bacteria,1R8AK@1224|Proteobacteria,42MTP@68525|delta/epsilon subdivisions,2WIST@28221|Deltaproteobacteria,2MIJP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
XH1_k127_4860697_2	706587.Desti_4580	2.106e-180	573.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,42MW8@68525|delta/epsilon subdivisions,2WKI6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
XH1_k127_4860697_6	933262.AXAM01000004_gene2373	5.376e-70	247.0	28KIX@1|root,2ZA44@2|Bacteria,1Q0JI@1224|Proteobacteria,42SSY@68525|delta/epsilon subdivisions,2WPVQ@28221|Deltaproteobacteria,2MK98@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
XH1_k127_4867504_10	1536772.R70723_00085	3.617e-27	116.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,26R3Y@186822|Paenibacillaceae	91061|Bacilli	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02535	Thymidylate_kin
XH1_k127_4867504_5	1333998.M2A_1448	5.662e-77	265.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2U787@28211|Alphaproteobacteria,4BSKE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycine zipper	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
XH1_k127_4867504_6	1410665.JNKR01000001_gene583	2.549e-51	186.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,4H4Y5@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
XH1_k127_4867504_11	1125863.JAFN01000001_gene2755	1.064e-21	96.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
XH1_k127_4867504_15	1304885.AUEY01000054_gene160	2.796e-09	65.0	29HYV@1|root,304VW@2|Bacteria,1RDPY@1224|Proteobacteria,42RXW@68525|delta/epsilon subdivisions,2WNTT@28221|Deltaproteobacteria,2MJZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4867504_0	1232410.KI421417_gene2751	1.651e-133	434.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,43S12@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	NeuB family	aroG-2	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
XH1_k127_4867504_8	357804.Ping_3340	4.017e-36	157.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,2QIEB@267894|Psychromonadaceae	1236|Gammaproteobacteria	M	TonB-dependent Receptor Plug Domain	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
XH1_k127_4867504_1	1121472.AQWN01000005_gene2525	3.805e-106	356.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,260PN@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
XH1_k127_4867504_2	395965.Msil_2318	1.141e-88	313.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,3NA0H@45404|Beijerinckiaceae	28211|Alphaproteobacteria	E	3-dehydroquinate synthase	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
XH1_k127_4867504_7	1269813.ATUL01000001_gene1124	1.081e-46	173.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1WY3G@135613|Chromatiales	135613|Chromatiales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
XH1_k127_4867504_4	443143.GM18_1395	4.511e-78	275.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2WJ8E@28221|Deltaproteobacteria,43TGZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
XH1_k127_4867504_3	706587.Desti_3701	5.239e-79	267.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,42N6H@68525|delta/epsilon subdivisions,2WNG7@28221|Deltaproteobacteria,2MRIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
XH1_k127_4867504_9	1123376.AUIU01000013_gene1763	2.217e-31	127.0	COG0511@1|root,COG0511@2|Bacteria,3J0PI@40117|Nitrospirae	40117|Nitrospirae	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
XH1_k127_4867504_12	1173028.ANKO01000112_gene4877	9.243e-19	95.0	COG0095@1|root,COG0095@2|Bacteria,1G0HD@1117|Cyanobacteria,1H90G@1150|Oscillatoriales	1117|Cyanobacteria	H	biotin lipoate A B protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
XH1_k127_4867504_14	1476973.JMMB01000007_gene1667	1.926e-10	70.0	COG0398@1|root,COG0398@2|Bacteria,1V3J1@1239|Firmicutes,24IF0@186801|Clostridia,25TA6@186804|Peptostreptococcaceae	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
XH1_k127_4867504_13	644282.Deba_1674	1.16e-14	76.0	COG1042@1|root,COG1042@2|Bacteria,1R8BC@1224|Proteobacteria,42PM4@68525|delta/epsilon subdivisions,2WM46@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CoA binding domain	-	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	CoA_binding_2,Succ_CoA_lig
XH1_k127_4876448_3	161156.JQKW01000010_gene306	7.987e-85	294.0	COG0077@1|root,COG0077@2|Bacteria,2GHQI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Chorismate mutase type II	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
XH1_k127_4876448_1	880072.Desac_0022	8.056e-90	314.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2MR8N@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
XH1_k127_4876448_6	1313265.JNIE01000002_gene803	3.021e-51	195.0	COG0287@1|root,COG0287@2|Bacteria,2G3QS@200783|Aquificae	200783|Aquificae	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
XH1_k127_4876448_0	767817.Desgi_2545	1.545e-119	398.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,2603K@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
XH1_k127_4876448_5	868864.Dester_0407	8.698e-54	201.0	COG0283@1|root,COG0283@2|Bacteria,2G3Z6@200783|Aquificae	200783|Aquificae	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
XH1_k127_4876448_4	589865.DaAHT2_1536	1.918e-79	281.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
XH1_k127_4876448_7	443143.GM18_1949	9.832e-14	73.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,42XRW@68525|delta/epsilon subdivisions,2WT0E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
XH1_k127_4876448_8	1321778.HMPREF1982_00256	4.585e-10	68.0	COG1309@1|root,COG1309@2|Bacteria,1UWAY@1239|Firmicutes,25MK8@186801|Clostridia,26BMW@186813|unclassified Clostridiales	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_4876448_2	1499967.BAYZ01000171_gene5603	6.513e-85	285.0	COG0459@1|root,COG0459@2|Bacteria,2NNM6@2323|unclassified Bacteria	2|Bacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
XH1_k127_4901133_0	338963.Pcar_1406	1.051e-102	355.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,43SAC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Ferrous iron transport protein B	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
XH1_k127_4901133_1	243231.GSU2226	2.916e-49	181.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,43TV2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
XH1_k127_4908403_1	439235.Dalk_3350	1.963e-64	225.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42M0R@68525|delta/epsilon subdivisions,2WJE6@28221|Deltaproteobacteria,2MMQB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_4908403_0	1157490.EL26_10575	1.629e-101	343.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,277WW@186823|Alicyclobacillaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_4908403_3	404589.Anae109_2678	5.215e-24	106.0	COG2030@1|root,COG2030@2|Bacteria,1NPDF@1224|Proteobacteria	1224|Proteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
XH1_k127_4908403_2	378806.STAUR_5070	6.914e-32	133.0	COG2030@1|root,COG2030@2|Bacteria,1QXU8@1224|Proteobacteria,43C6S@68525|delta/epsilon subdivisions,2X7GZ@28221|Deltaproteobacteria,2YW6B@29|Myxococcales	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
XH1_k127_4961077_9	56780.SYN_02121	1.936e-32	130.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MQEZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
XH1_k127_4961077_1	1121335.Clst_2614	7.871e-122	402.0	COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,247W5@186801|Clostridia,3WJDT@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the LDH2 MDH2 oxidoreductase family	mdh	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
XH1_k127_4961077_2	1304885.AUEY01000004_gene1001	2.489e-96	324.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2WIPW@28221|Deltaproteobacteria,2MI53@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Radical SAM domain protein	yhcC-1	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
XH1_k127_4961077_7	1286171.EAL2_c17910	3.024e-66	237.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,25VHB@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
XH1_k127_4961077_5	439235.Dalk_3365	1.231e-83	286.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,42Z4Q@68525|delta/epsilon subdivisions,2WU89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_4961077_3	1449126.JQKL01000008_gene299	4.478e-96	327.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,26A52@186813|unclassified Clostridiales	186801|Clostridia	C	Acetokinase family	buk	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
XH1_k127_4961077_8	555088.DealDRAFT_2600	2.416e-33	135.0	COG4747@1|root,COG4747@2|Bacteria,1V7U2@1239|Firmicutes,24JE5@186801|Clostridia,42JZR@68298|Syntrophomonadaceae	186801|Clostridia	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
XH1_k127_4961077_6	941824.TCEL_01583	1.11e-67	242.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,36DC6@31979|Clostridiaceae	186801|Clostridia	C	phosphate butyryltransferase	ptb	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747,GO:0050182	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
XH1_k127_4961077_4	673860.AciM339_0744	1.475e-88	309.0	COG1042@1|root,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,3F326@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	CoA binding domain	acdA	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	CoA_binding_2,Succ_CoA_lig
XH1_k127_4961077_0	96561.Dole_0112	1.379e-160	520.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,42Q72@68525|delta/epsilon subdivisions,2WM9N@28221|Deltaproteobacteria,2MJN1@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_4972368_0	644282.Deba_1628	6.419e-211	671.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
XH1_k127_4972368_2	1121468.AUBR01000032_gene1193	1.268e-77	269.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,42EMQ@68295|Thermoanaerobacterales	186801|Clostridia	E	ABC transporter related	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
XH1_k127_4972368_1	96561.Dole_3008	4.43e-97	323.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42PJN@68525|delta/epsilon subdivisions,2WIPZ@28221|Deltaproteobacteria,2MJJS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
XH1_k127_5019956_2	909663.KI867149_gene3444	9.522e-12	69.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,42XTP@68525|delta/epsilon subdivisions,2WT04@28221|Deltaproteobacteria,2MQR7@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
XH1_k127_5019956_1	439235.Dalk_3074	7.03e-27	124.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WKVG@28221|Deltaproteobacteria,2MJ11@213118|Desulfobacterales	28221|Deltaproteobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
XH1_k127_5019956_0	500635.MITSMUL_04926	6.593e-51	190.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H2C6@909932|Negativicutes	909932|Negativicutes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
XH1_k127_5030100_5	56780.SYN_03850	5.617e-29	120.0	2E20Q@1|root,32X8P@2|Bacteria,1NF7J@1224|Proteobacteria,42V60@68525|delta/epsilon subdivisions,2WRJ8@28221|Deltaproteobacteria,2MSE9@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5030100_3	1123325.JHUV01000008_gene812	1.147e-45	169.0	COG3271@1|root,COG3271@2|Bacteria,2G4YK@200783|Aquificae	200783|Aquificae	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Peptidase_C39_2
XH1_k127_5030100_4	1158345.JNLL01000001_gene1307	2.269e-34	140.0	COG3063@1|root,COG3063@2|Bacteria,2G55J@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
XH1_k127_5030100_2	946483.Cenrod_1878	4.759e-50	181.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2VT9K@28216|Betaproteobacteria,4ADW1@80864|Comamonadaceae	28216|Betaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
XH1_k127_5030100_1	1042375.AFPL01000016_gene55	1.348e-51	187.0	COG1585@1|root,COG1585@2|Bacteria,1RJHH@1224|Proteobacteria,1SZTE@1236|Gammaproteobacteria,46BS5@72275|Alteromonadaceae	1236|Gammaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
XH1_k127_5030100_0	1232683.ADIMK_2633	9.783e-124	402.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,465XW@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
XH1_k127_5036358_0	1123366.TH3_14959	1.989e-119	393.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2JQAX@204441|Rhodospirillales	204441|Rhodospirillales	V	ABC-type multidrug transport system, ATPase and permease	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
XH1_k127_5036358_2	224324.aq_1656	2.039e-45	178.0	COG1663@1|root,COG1663@2|Bacteria,2G4XJ@200783|Aquificae	200783|Aquificae	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
XH1_k127_5036358_1	926561.KB900620_gene3058	2.489e-46	175.0	COG0241@1|root,COG0241@2|Bacteria,1V6XD@1239|Firmicutes,24IZ4@186801|Clostridia	186801|Clostridia	E	D,d-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
XH1_k127_5040835_0	631362.Thi970DRAFT_02826	1.911e-158	520.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWK7@135613|Chromatiales	135613|Chromatiales	F	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
XH1_k127_5040835_4	1123326.JFBL01000004_gene2112	1.184e-99	343.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
XH1_k127_5040835_1	257310.BB0139	1.133e-153	494.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2VJDB@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46,5.1.3.2,5.1.3.7	ko:K01710,ko:K01784,ko:K02473,ko:K08678	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R00418,R01384,R02984,R06513	RC00289,RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
XH1_k127_5040835_2	765952.PUV_27280	3.366e-142	456.0	COG0451@1|root,COG0451@2|Bacteria,2JGMJ@204428|Chlamydiae	204428|Chlamydiae	GM	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
XH1_k127_5040835_3	1337936.IJ00_17795	1.997e-133	430.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1HK6A@1161|Nostocales	1117|Cyanobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
XH1_k127_5052315_0	56780.SYN_02642	9.418e-166	532.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2MRCD@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
XH1_k127_5052315_1	338963.Pcar_0623	9.031e-38	151.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,43SCW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
XH1_k127_5061052_3	443254.Marpi_0107	2.11e-19	92.0	COG1027@1|root,COG1027@2|Bacteria,2GCJN@200918|Thermotogae	200918|Thermotogae	E	PFAM fumarate lyase	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	Lyase_1
XH1_k127_5061052_1	351627.Csac_0491	2.862e-104	349.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,42ERD@68295|Thermoanaerobacterales	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	hydE	-	2.8.1.6,5.4.99.58	ko:K01012,ko:K16180	ko00300,ko00780,ko01100,ko01120,map00300,map00780,map01100,map01120	M00123,M00573,M00577	R01078,R10010	RC00441,RC02995	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
XH1_k127_5061052_0	56780.SYN_02133	1.955e-219	688.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42Q6J@68525|delta/epsilon subdivisions,2WKXA@28221|Deltaproteobacteria,2MR5K@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Biotin and Thiamin Synthesis associated	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
XH1_k127_5061052_2	203119.Cthe_0653	3.112e-27	113.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,3WM14@541000|Ruminococcaceae	186801|Clostridia	K	iron-only hydrogenase system regulator	-	-	-	-	-	-	-	-	-	-	-	-	NikR_C
XH1_k127_5061052_4	56780.SYN_01370	6.237e-14	72.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1MUM1@1224|Proteobacteria,42PI4@68525|delta/epsilon subdivisions,2WJ5A@28221|Deltaproteobacteria,2MQ58@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Iron hydrogenase small subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,NADH-G_4Fe-4S_3
XH1_k127_5083493_2	1279009.ADICEAN_03738	8.357e-65	226.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,47M7J@768503|Cytophagia	976|Bacteroidetes	C	PFAM NADH flavin oxidoreductase NADH oxidase	nemA	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
XH1_k127_5083493_1	96561.Dole_0296	2.187e-90	304.0	COG2050@1|root,COG2050@2|Bacteria,1QJP9@1224|Proteobacteria,436KC@68525|delta/epsilon subdivisions,2X17C@28221|Deltaproteobacteria,2MJZN@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
XH1_k127_5083493_0	96561.Dole_1860	4.594e-214	672.0	COG1960@1|root,COG1960@2|Bacteria,1R6R2@1224|Proteobacteria,42NTR@68525|delta/epsilon subdivisions,2WKRA@28221|Deltaproteobacteria,2MIWC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_5083493_3	768706.Desor_2538	1.21e-27	116.0	2DXYQ@1|root,3477W@2|Bacteria,1W1DR@1239|Firmicutes,252WC@186801|Clostridia,2665T@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5160989_0	1265505.ATUG01000001_gene4588	1.114e-277	865.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,42PEV@68525|delta/epsilon subdivisions,2WKW5@28221|Deltaproteobacteria,2MJ1U@213118|Desulfobacterales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	tssH	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
XH1_k127_5160989_1	497964.CfE428DRAFT_2260	1.081e-18	95.0	COG3517@1|root,COG3517@2|Bacteria	2|Bacteria	S	type VI secretion protein	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA,VipB
XH1_k127_5173196_3	1265505.ATUG01000001_gene4616	8.448e-12	66.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2MJKU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
XH1_k127_5173196_1	1167006.UWK_02686	3.611e-47	184.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
XH1_k127_5173196_0	1167006.UWK_02685	1.023e-108	363.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2MHTH@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase,cNMP_binding
XH1_k127_5173196_2	1265505.ATUG01000002_gene1251	2.112e-40	150.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42N7M@68525|delta/epsilon subdivisions,2WIJ0@28221|Deltaproteobacteria,2MITQ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
XH1_k127_522801_5	96561.Dole_3114	2.34e-41	158.0	COG0463@1|root,COG0463@2|Bacteria,1QW1R@1224|Proteobacteria,42R1R@68525|delta/epsilon subdivisions,2X72M@28221|Deltaproteobacteria,2MNMW@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
XH1_k127_522801_9	1485545.JQLW01000009_gene201	2.179e-12	76.0	COG1266@1|root,COG1266@2|Bacteria,1NID0@1224|Proteobacteria	1224|Proteobacteria	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
XH1_k127_522801_0	690850.Desaf_0072	1.533e-156	514.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2M8QA@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
XH1_k127_522801_7	56780.SYN_00044	1.067e-30	130.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,2MQNV@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
XH1_k127_522801_4	1121918.ARWE01000001_gene3464	3.899e-42	169.0	COG0683@1|root,COG0683@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria,43S82@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	LppC putative lipoprotein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC,Peripla_BP_6,TPR_16,TPR_6
XH1_k127_522801_8	1121448.DGI_2197	1.365e-12	70.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria,2MDCV@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
XH1_k127_522801_1	96561.Dole_3171	2.391e-76	265.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2MI7G@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
XH1_k127_522801_6	1408473.JHXO01000007_gene663	2.618e-35	153.0	COG0614@1|root,COG0614@2|Bacteria,4PIZ2@976|Bacteroidetes,2FQAM@200643|Bacteroidia	976|Bacteroidetes	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
XH1_k127_522801_3	997346.HMPREF9374_3132	4.811e-54	213.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAUK@91061|Bacilli,27AZ3@186824|Thermoactinomycetaceae	91061|Bacilli	P	FecCD transport family	fecD1	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
XH1_k127_522801_2	863239.AFIZ01000032_gene1874	2.11e-61	220.0	COG1120@1|root,COG1120@2|Bacteria,2GJ49@201174|Actinobacteria,22JP3@1653|Corynebacteriaceae	201174|Actinobacteria	HP	transport systems ATPase components	cbrD	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
XH1_k127_522801_10	639282.DEFDS_1091	2.194e-09	59.0	COG0782@1|root,COG0782@2|Bacteria,2GFGG@200930|Deferribacteres	200930|Deferribacteres	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
XH1_k127_5230407_1	357808.RoseRS_3299	1.242e-80	278.0	COG0578@1|root,COG0578@2|Bacteria,2G63S@200795|Chloroflexi,3750F@32061|Chloroflexia	32061|Chloroflexia	C	BFD domain protein 2Fe-2S -binding domain protein	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
XH1_k127_5230407_2	765420.OSCT_2315	3.187e-57	215.0	COG3075@1|root,COG3075@2|Bacteria,2G877@200795|Chloroflexi,374VB@32061|Chloroflexia	32061|Chloroflexia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
XH1_k127_5230407_0	868595.Desca_0122	1.341e-81	289.0	COG0247@1|root,COG0247@2|Bacteria,1TQJM@1239|Firmicutes,24CFC@186801|Clostridia,260T9@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
XH1_k127_5230407_3	443143.GM18_1936	0.0003196	46.0	2EQD3@1|root,33HZ5@2|Bacteria,1P9PI@1224|Proteobacteria,433DW@68525|delta/epsilon subdivisions,2WX7R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5240126_0	706587.Desti_2509	2.115e-216	696.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,42QJC@68525|delta/epsilon subdivisions,2WPI2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_10,TPR_16,TPR_19,TPR_4,TPR_8
XH1_k127_5240126_1	338966.Ppro_0407	1.309e-47	179.0	COG0366@1|root,COG0366@2|Bacteria,1PDXT@1224|Proteobacteria	1224|Proteobacteria	G	alpha amylase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
XH1_k127_5248534_0	1499967.BAYZ01000013_gene6451	3.006e-209	659.0	COG0033@1|root,COG0033@2|Bacteria,2NS5G@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgm	GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1376,iECED1_1282.ECED1_0670,iECNA114_1301.ECNA114_0627,iECOK1_1307.ECOK1_0699,iECP_1309.ECP_0709,iECS88_1305.ECS88_0725,iJN678.pgm,iLF82_1304.LF82_1632,iNRG857_1313.NRG857_03110,iUMN146_1321.UM146_14115,iYL1228.KPN_00711	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
XH1_k127_5248534_2	1121405.dsmv_1480	2.261e-92	312.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,42MFY@68525|delta/epsilon subdivisions,2WJS5@28221|Deltaproteobacteria,2MJQ1@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
XH1_k127_5248534_1	1379281.AVAG01000025_gene1863	1.499e-121	396.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,42NVT@68525|delta/epsilon subdivisions,2WJ9C@28221|Deltaproteobacteria,2M9NJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
XH1_k127_5248534_3	485915.Dret_0478	8.43e-19	90.0	COG0765@1|root,COG0765@2|Bacteria,1R4RU@1224|Proteobacteria,42PW7@68525|delta/epsilon subdivisions,2WK9J@28221|Deltaproteobacteria,2M8W2@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
XH1_k127_5261694_6	592015.HMPREF1705_00887	3.042e-134	437.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
XH1_k127_5261694_9	706587.Desti_5099	6.663e-91	308.0	COG0697@1|root,COG0697@2|Bacteria,1MUQ7@1224|Proteobacteria,42R74@68525|delta/epsilon subdivisions,2WMRT@28221|Deltaproteobacteria,2MRGD@213462|Syntrophobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
XH1_k127_5261694_3	1265505.ATUG01000002_gene1292	4.685e-160	514.0	COG1960@1|root,COG1960@2|Bacteria,1R6R2@1224|Proteobacteria,42NTR@68525|delta/epsilon subdivisions,2WKRA@28221|Deltaproteobacteria,2MIWC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_5261694_1	1121430.JMLG01000002_gene1106	9.121e-189	604.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248QX@186801|Clostridia,260AJ@186807|Peptococcaceae	186801|Clostridia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_5261694_2	1121472.AQWN01000006_gene1669	5.49e-161	515.0	COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,24E5F@186801|Clostridia,2618E@186807|Peptococcaceae	186801|Clostridia	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_5261694_0	335543.Sfum_1073	3.644e-269	839.0	COG4868@1|root,COG4868@2|Bacteria,1NN03@1224|Proteobacteria,42P46@68525|delta/epsilon subdivisions,2WKVV@28221|Deltaproteobacteria,2MR6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
XH1_k127_5261694_4	643562.Daes_1852	1.969e-147	488.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria,2M8S3@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
XH1_k127_5261694_20	56780.SYN_01962	6.716e-41	163.0	COG0500@1|root,COG2226@2|Bacteria,1N4AW@1224|Proteobacteria,42UAK@68525|delta/epsilon subdivisions,2WQZC@28221|Deltaproteobacteria,2MR5P@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5261694_7	396588.Tgr7_2953	5.396e-115	387.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WX0Q@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
XH1_k127_5261694_19	335543.Sfum_2470	1.884e-43	166.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,2MRVA@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
XH1_k127_5261694_21	1094980.Mpsy_1303	1.255e-29	121.0	COG0526@1|root,arCOG01972@2157|Archaea,2XXRJ@28890|Euryarchaeota,2N9YG@224756|Methanomicrobia	224756|Methanomicrobia	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
XH1_k127_5261694_10	1211035.CD30_09515	3.27e-86	295.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,3IW96@400634|Lysinibacillus	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
XH1_k127_5261694_18	392500.Swoo_0965	1.536e-52	203.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria,2Q8UA@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
XH1_k127_5261694_25	326297.Sama_1450	1.12e-05	53.0	COG5633@1|root,COG5633@2|Bacteria,1NAZT@1224|Proteobacteria,1SDRP@1236|Gammaproteobacteria,2QC4X@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1425)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1425
XH1_k127_5261694_17	998088.B565_1423	1.489e-57	209.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S30E@1236|Gammaproteobacteria,1Y62F@135624|Aeromonadales	135624|Aeromonadales	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	DUF3280,LpoB
XH1_k127_5261694_22	1304275.C41B8_15570	2.221e-25	113.0	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
XH1_k127_5261694_11	106370.Francci3_0048	2.44e-69	267.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
XH1_k127_5261694_15	1097668.BYI23_A002900	4.916e-59	214.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria,1K0W9@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
XH1_k127_5261694_12	177439.DP0167	3.792e-69	241.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria,2MIYB@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
XH1_k127_5261694_16	177439.DP0166	5.557e-59	211.0	COG0602@1|root,COG0602@2|Bacteria	2|Bacteria	H	queuosine metabolic process	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	1.97.1.4,4.3.99.3	ko:K04068,ko:K10026	ko00790,ko01100,map00790,map01100	-	R04710,R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
XH1_k127_5261694_13	439235.Dalk_0307	4.395e-65	229.0	COG0045@1|root,COG0045@2|Bacteria,1REBV@1224|Proteobacteria,42S1F@68525|delta/epsilon subdivisions,2WNW1@28221|Deltaproteobacteria,2MJUN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5
XH1_k127_5261694_14	667014.Thein_1558	8.07e-60	218.0	COG0042@1|root,COG0042@2|Bacteria,2GI6M@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Dihydrouridine synthase (Dus)	-	-	-	-	-	-	-	-	-	-	-	-	Dus
XH1_k127_5261694_5	1123508.JH636445_gene6869	1.407e-146	474.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
XH1_k127_5261694_8	1304880.JAGB01000002_gene2382	2.312e-100	341.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
XH1_k127_5261694_24	1125863.JAFN01000001_gene1709	3.652e-06	51.0	2EQD3@1|root,33HZ5@2|Bacteria,1P9PI@1224|Proteobacteria,433DW@68525|delta/epsilon subdivisions,2WX7R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5261967_0	1125863.JAFN01000001_gene910	9.588e-236	740.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
XH1_k127_5261967_1	742817.HMPREF9449_02421	1.123e-48	198.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,2FPYJ@200643|Bacteroidia,22XFT@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
XH1_k127_5284712_1	525904.Tter_0083	2.166e-06	60.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,NACHT,SIR2_2,TPR_1,TPR_11,TPR_2,TPR_8
XH1_k127_5284712_0	1125863.JAFN01000001_gene3506	3.11e-71	252.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
XH1_k127_5298020_2	1121405.dsmv_2161	1.19e-87	293.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
XH1_k127_5298020_7	331678.Cphamn1_0872	3.636e-29	122.0	COG2361@1|root,COG2361@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
XH1_k127_5298020_5	1173028.ANKO01000044_gene805	2.458e-32	128.0	COG1669@1|root,COG1669@2|Bacteria,1G804@1117|Cyanobacteria,1HCHE@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
XH1_k127_5298020_8	1232437.KL661991_gene494	5.42e-17	81.0	2EGKD@1|root,33ACM@2|Bacteria,1NAVJ@1224|Proteobacteria,42XZU@68525|delta/epsilon subdivisions,2WX7U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5298020_6	1046714.AMRX01000008_gene1106	1.655e-29	125.0	COG5276@1|root,COG5276@2|Bacteria,1R8AF@1224|Proteobacteria,1SCCG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5298020_9	296591.Bpro_2876	8.055e-05	52.0	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,2VVPQ@28216|Betaproteobacteria,4AFIS@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Type II transport protein GspH	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
XH1_k127_5298020_4	1120973.AQXL01000129_gene2476	6.79e-34	138.0	COG1683@1|root,COG1683@2|Bacteria,1V700@1239|Firmicutes,4HJH0@91061|Bacilli,278GS@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein of unknown function (DUF523)	ybbK	-	-	-	-	-	-	-	-	-	-	-	DUF523
XH1_k127_5298020_3	56780.SYN_00888	6.713e-77	263.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,2MRWI@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
XH1_k127_5298020_0	443143.GM18_1767	4.072e-134	436.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,43RZ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
XH1_k127_5298020_1	96561.Dole_1082	2.795e-106	359.0	COG1906@1|root,COG1906@2|Bacteria,1RAQQ@1224|Proteobacteria,42QZ0@68525|delta/epsilon subdivisions,2WMXK@28221|Deltaproteobacteria,2MJKT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
XH1_k127_5338402_1	439235.Dalk_1066	1.144e-135	448.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42Y9H@68525|delta/epsilon subdivisions,2WUPN@28221|Deltaproteobacteria,2MN1Q@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
XH1_k127_5338402_6	548479.HMPREF0573_10235	1.383e-06	59.0	COG3255@1|root,COG3255@2|Bacteria,2IJUY@201174|Actinobacteria	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5338402_3	243231.GSU0664	4.146e-107	358.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,43T1T@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
XH1_k127_5338402_7	522772.Dacet_2840	8.955e-06	54.0	COG0642@1|root,COG2205@2|Bacteria,2GEKQ@200930|Deferribacteres	200930|Deferribacteres	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
XH1_k127_5338402_8	1112217.PPL19_14909	5.458e-05	49.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria	1224|Proteobacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
XH1_k127_5338402_4	224324.aq_1731	1.484e-28	124.0	COG0212@1|root,COG0212@2|Bacteria,2G47M@200783|Aquificae	200783|Aquificae	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
XH1_k127_5338402_0	1232410.KI421425_gene1521	2.595e-177	569.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,43SDT@69541|Desulfuromonadales	28221|Deltaproteobacteria	A	Domain of unknown function (DUF3552)	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
XH1_k127_5338402_2	1144325.PMI22_04806	7.234e-125	404.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iJN746.PP_0436	S4,tRNA-synt_1b
XH1_k127_53508_7	644282.Deba_1712	1.754e-105	354.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42MTH@68525|delta/epsilon subdivisions,2WJQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
XH1_k127_53508_2	338963.Pcar_0561	1.822e-197	629.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,43T92@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
XH1_k127_53508_8	56780.SYN_01017	6.232e-103	341.0	COG0123@1|root,COG0123@2|Bacteria,1RBR4@1224|Proteobacteria,42R2Z@68525|delta/epsilon subdivisions,2WN6H@28221|Deltaproteobacteria,2MR74@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
XH1_k127_53508_3	56780.SYN_00886	2.522e-187	590.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,2MQH8@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Phosphofructokinase	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
XH1_k127_53508_17	1177181.T9A_00786	2.704e-14	76.0	2E7TI@1|root,3328N@2|Bacteria,1NCCK@1224|Proteobacteria,1SDE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TRL-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	TRL
XH1_k127_53508_4	1499967.BAYZ01000009_gene5347	8.596e-153	494.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
XH1_k127_53508_12	1379858.N508_01985	2.287e-66	233.0	COG0652@1|root,COG0652@2|Bacteria,2GG0J@200930|Deferribacteres	200930|Deferribacteres	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
XH1_k127_53508_13	349521.HCH_01478	1.014e-55	201.0	COG2816@1|root,COG2816@2|Bacteria,1REUJ@1224|Proteobacteria	1224|Proteobacteria	L	PFAM NUDIX hydrolase	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,Nudix_N_2
XH1_k127_53508_10	1232437.KL661956_gene2399	2.187e-94	328.0	COG0697@1|root,COG0697@2|Bacteria,1PX5W@1224|Proteobacteria,42MGR@68525|delta/epsilon subdivisions,2WJSI@28221|Deltaproteobacteria,2MI95@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
XH1_k127_53508_16	511051.CSE_15390	5.639e-15	81.0	COG1502@1|root,COG2374@1|root,COG1502@2|Bacteria,COG2374@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	xynX1	-	3.1.3.8	ko:K01083,ko:K06131,ko:K06915	ko00562,ko00564,ko01100,map00562,map00564,map01100	-	R03371,R07390	RC00017,RC00078	ko00000,ko00001,ko01000	-	-	-	Exo_endo_phos,F5_F8_type_C,LTD,PLDc_2,SLH
XH1_k127_53508_6	1122604.JONR01000026_gene2999	1.394e-110	362.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,1RSCI@1236|Gammaproteobacteria,1X4E8@135614|Xanthomonadales	135614|Xanthomonadales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_53508_5	177437.HRM2_44930	3.094e-118	387.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,42N9Z@68525|delta/epsilon subdivisions,2WIKQ@28221|Deltaproteobacteria,2MHU6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
XH1_k127_53508_14	1229780.BN381_130241	1.172e-35	146.0	COG2220@1|root,COG2220@2|Bacteria,2GMFQ@201174|Actinobacteria	201174|Actinobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
XH1_k127_53508_11	909663.KI867150_gene29	5.671e-82	286.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2MQPY@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	ldh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
XH1_k127_53508_15	279714.FuraDRAFT_1580	1.083e-15	82.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,2KR2F@206351|Neisseriales	206351|Neisseriales	S	Belongs to the UPF0307 family	-	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
XH1_k127_53508_0	439235.Dalk_0589	3.033e-225	710.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria,2MI60@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
XH1_k127_53508_1	1304885.AUEY01000010_gene1638	1.583e-217	683.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria,2MJMW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
XH1_k127_53508_9	1121405.dsmv_2236	9.036e-103	345.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,42PVD@68525|delta/epsilon subdivisions,2WM2C@28221|Deltaproteobacteria,2MIPY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pfam:UPF0118	-	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
XH1_k127_5366744_1	525897.Dbac_1637	1.795e-122	399.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2M8BZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM transferase hexapeptide repeat containing protein	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
XH1_k127_5366744_3	331678.Cphamn1_2231	4.91e-91	304.0	COG0822@1|root,COG2906@1|root,COG0822@2|Bacteria,COG2906@2|Bacteria,1FE8S@1090|Chlorobi	1090|Chlorobi	CP	BFD domain protein 2Fe-2S -binding domain protein	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU_N
XH1_k127_5366744_0	290315.Clim_2175	8.318e-177	562.0	COG1104@1|root,COG1104@2|Bacteria,1FDUZ@1090|Chlorobi	1090|Chlorobi	E	PFAM aminotransferase class V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
XH1_k127_5366744_2	398512.JQKC01000001_gene2200	6.411e-101	335.0	COG5297@1|root,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta-lactamase,CBM60,CBM_2,Cellulase,DUF1593,PSCyt3,fn3
XH1_k127_5406062_0	323259.Mhun_1971	7.25e-77	282.0	COG1948@1|root,arCOG02284@2157|Archaea,2XT7B@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM Beta propeller domain	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	Beta_propel,Inhibitor_I42
XH1_k127_5409023_1	1123487.KB892866_gene1648	1.209e-32	137.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VJF9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
XH1_k127_5409023_0	580340.Tlie_1599	0.0	1093.0	COG0542@1|root,COG0542@2|Bacteria,3TA3A@508458|Synergistetes	508458|Synergistetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
XH1_k127_5410816_1	1227349.C170_06454	6.628e-17	90.0	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1UII2@1239|Firmicutes,4HGW5@91061|Bacilli,26QEY@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
XH1_k127_5410816_0	1121468.AUBR01000019_gene2622	7.642e-94	317.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,42ERP@68295|Thermoanaerobacterales	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
XH1_k127_5443619_3	439235.Dalk_1739	1.193e-70	241.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,42ZTX@68525|delta/epsilon subdivisions,2WVID@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2224	ECH_1
XH1_k127_5443619_2	96561.Dole_2374	5.611e-117	392.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2MJ7T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
XH1_k127_5443619_0	177437.HRM2_09530	3.671e-175	568.0	COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,42R7V@68525|delta/epsilon subdivisions,2WN3A@28221|Deltaproteobacteria,2MMB0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3413)	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	DUF3413,Sulfatase
XH1_k127_5443619_5	909663.KI867150_gene138	4.454e-30	126.0	COG0589@1|root,COG0589@2|Bacteria,1NNUM@1224|Proteobacteria,43A9J@68525|delta/epsilon subdivisions,2X2D7@28221|Deltaproteobacteria,2MSB9@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
XH1_k127_5443619_4	335543.Sfum_0395	8.172e-53	192.0	COG3945@1|root,COG3945@2|Bacteria,1N3AR@1224|Proteobacteria,42UWM@68525|delta/epsilon subdivisions,2WQEC@28221|Deltaproteobacteria,2MQIV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
XH1_k127_5443619_1	1304885.AUEY01000085_gene2476	2.345e-120	392.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,42NPH@68525|delta/epsilon subdivisions,2WIXM@28221|Deltaproteobacteria,2MPSE@213118|Desulfobacterales	28221|Deltaproteobacteria	M	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
XH1_k127_5444150_2	439235.Dalk_2103	1.019e-126	407.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,42S03@68525|delta/epsilon subdivisions,2WNW5@28221|Deltaproteobacteria,2MQ1F@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
XH1_k127_5444150_1	439235.Dalk_2102	5.304e-132	424.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2MHNA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
XH1_k127_5444150_0	439235.Dalk_2101	2.548e-174	557.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,42QG7@68525|delta/epsilon subdivisions,2WP24@28221|Deltaproteobacteria,2MPI1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
XH1_k127_5444150_3	439235.Dalk_2100	7.15e-52	186.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_5452539_2	1123355.JHYO01000020_gene330	1.89e-60	218.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2TR9Q@28211|Alphaproteobacteria,36XMP@31993|Methylocystaceae	28211|Alphaproteobacteria	K	Sigma-70, region 4	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
XH1_k127_5452539_4	944481.JAFP01000001_gene1269	8.034e-26	111.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2M76J@213113|Desulfurellales	28221|Deltaproteobacteria	O	CS domain	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
XH1_k127_5452539_5	266117.Rxyl_3211	7.433e-15	81.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4CQFC@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
XH1_k127_5452539_1	697284.ERIC2_c41250	5.284e-83	292.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,26RSI@186822|Paenibacillaceae	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
XH1_k127_5452539_3	1280685.AUKC01000045_gene3047	4.087e-39	154.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,4BXPX@830|Butyrivibrio	186801|Clostridia	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
XH1_k127_5452539_0	316067.Geob_3838	9.785e-102	344.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,43T3A@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
XH1_k127_5460852_3	646529.Desaci_2135	6.375e-32	127.0	COG1149@1|root,COG1149@2|Bacteria,1V767@1239|Firmicutes,24C3D@186801|Clostridia	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_9,Flavodoxin_5
XH1_k127_5460852_0	1163617.SCD_n00016	2.068e-126	409.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
XH1_k127_5460852_1	76114.c2A200	4.028e-111	372.0	COG0457@1|root,COG0457@2|Bacteria,1R4RP@1224|Proteobacteria,2W224@28216|Betaproteobacteria,2KYMR@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037
XH1_k127_5460852_2	933262.AXAM01000022_gene3219	7.544e-52	190.0	2DM2Z@1|root,31HGC@2|Bacteria,1N0CJ@1224|Proteobacteria,42TZ3@68525|delta/epsilon subdivisions,2WQCR@28221|Deltaproteobacteria,2MKII@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4125
XH1_k127_5460852_4	1206733.BAGC01000044_gene1024	5.797e-10	60.0	COG1960@1|root,COG1960@2|Bacteria,2GNBW@201174|Actinobacteria,4FUT8@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE23	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
XH1_k127_547258_13	1002809.SSIL_3071	3.155e-05	55.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4HAU4@91061|Bacilli,26D9K@186818|Planococcaceae	91061|Bacilli	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	iYO844.BSU15530	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
XH1_k127_547258_9	1121448.DGI_0333	4.368e-20	102.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,42V77@68525|delta/epsilon subdivisions,2WRQF@28221|Deltaproteobacteria,2MCBQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
XH1_k127_547258_11	1408311.JNJM01000002_gene1184	2.102e-14	81.0	COG3715@1|root,COG3715@2|Bacteria,1UZHW@1239|Firmicutes,25C3G@186801|Clostridia	186801|Clostridia	G	PTS system sorbose-specific iic component	-	-	-	ko:K02795,ko:K19508	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276,M00764	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1,4.A.6.1.19	-	-	EII-Sor
XH1_k127_547258_8	56780.SYN_02845	3.564e-28	119.0	COG3444@1|root,COG3444@2|Bacteria,1R4ES@1224|Proteobacteria,42VCG@68525|delta/epsilon subdivisions,2WRN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTSIIB_sorb
XH1_k127_547258_7	909663.KI867150_gene940	3.362e-35	138.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria,2MQJY@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PTS system fructose IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
XH1_k127_547258_2	439235.Dalk_1358	6.123e-73	256.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,2MJ01@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
XH1_k127_547258_10	644282.Deba_1234	4.815e-16	81.0	COG1366@1|root,COG1366@2|Bacteria,1NDC7@1224|Proteobacteria,42XY3@68525|delta/epsilon subdivisions,2WSWC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
XH1_k127_547258_6	644282.Deba_1232	1.236e-41	159.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,42SAC@68525|delta/epsilon subdivisions,2WP7J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	cheY34H-1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
XH1_k127_547258_0	644282.Deba_1231	1.639e-193	625.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Signal transducing histidine kinase homodimeric	cheA36H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
XH1_k127_547258_3	1218084.BBJK01000136_gene7227	7.028e-71	261.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJE4@28216|Betaproteobacteria,1K0S8@119060|Burkholderiaceae	28216|Betaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
XH1_k127_547258_5	204773.HEAR1302	4.012e-44	165.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,4745S@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	cheW8	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
XH1_k127_547258_1	644282.Deba_1229	5.538e-92	310.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42MR2@68525|delta/epsilon subdivisions,2WKKH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg
XH1_k127_547258_4	644282.Deba_1228	2.721e-48	177.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,42THA@68525|delta/epsilon subdivisions,2WNG6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
XH1_k127_5477085_2	644282.Deba_2846	9.587e-12	73.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	formate C-acetyltransferase glycine radical	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
XH1_k127_5477085_1	439235.Dalk_0162	1.307e-105	351.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
XH1_k127_5477085_0	439235.Dalk_0163	9.471e-111	367.0	COG1180@1|root,COG1180@2|Bacteria,1QJHU@1224|Proteobacteria,42R2E@68525|delta/epsilon subdivisions,2WMYN@28221|Deltaproteobacteria,2MJPF@213118|Desulfobacterales	1224|Proteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
XH1_k127_555758_3	1499967.BAYZ01000104_gene3626	9.019e-29	117.0	COG2331@1|root,COG2331@2|Bacteria,2NQXD@2323|unclassified Bacteria	2|Bacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
XH1_k127_555758_2	573413.Spirs_3800	5.12e-141	458.0	COG0513@1|root,COG0513@2|Bacteria,2J5U7@203691|Spirochaetes	203691|Spirochaetes	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
XH1_k127_555758_4	420662.Mpe_A0013	4.039e-11	65.0	2CIC8@1|root,33JK4@2|Bacteria,1NH5Z@1224|Proteobacteria,2VYDU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_555758_0	886293.Sinac_1351	1.699e-277	871.0	COG0058@1|root,COG0058@2|Bacteria,2IY0J@203682|Planctomycetes	203682|Planctomycetes	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
XH1_k127_555758_1	933262.AXAM01000151_gene828	6.855e-179	578.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
XH1_k127_5573689_1	56780.SYN_00600	3.799e-239	755.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2WJ51@28221|Deltaproteobacteria,2MQ4D@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	iAF987.Gmet_0119	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
XH1_k127_5573689_2	56780.SYN_00601	1.03e-132	432.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2WJ8B@28221|Deltaproteobacteria,2MQBP@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	TIGRFAM hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
XH1_k127_5573689_3	443254.Marpi_1446	1.032e-17	88.0	COG0071@1|root,COG0071@2|Bacteria,2GDCG@200918|Thermotogae	200918|Thermotogae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
XH1_k127_5573689_0	667014.Thein_1862	3.202e-305	954.0	COG0466@1|root,COG0466@2|Bacteria,2GH8Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
XH1_k127_5628254_0	56780.SYN_02770	9.091e-285	882.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2MREZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Inorganic H+ pyrophosphatase	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
XH1_k127_5628254_1	644282.Deba_0084	4.292e-270	843.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1R561@1224|Proteobacteria,42NEB@68525|delta/epsilon subdivisions,2WM1V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CJ	Acetyl-CoA hydrolase transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
XH1_k127_5628254_2	1121405.dsmv_0170	8.41e-249	781.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2MHT0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
XH1_k127_5628254_10	395019.Bmul_6005	3.9e-05	55.0	COG0446@1|root,COG0446@2|Bacteria,1MXA9@1224|Proteobacteria,2VHVI@28216|Betaproteobacteria,1K1JZ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	BFD domain protein 2Fe-2S -binding domain protein	ooxA	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Pyr_redox_2
XH1_k127_5628254_9	1121468.AUBR01000001_gene402	1.574e-27	124.0	COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,42EXW@68295|Thermoanaerobacterales	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	3.6.4.12	ko:K02316,ko:K17680	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03029,ko03032	-	-	-	DnaB_C,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
XH1_k127_5628254_5	1121405.dsmv_0904	5.067e-141	455.0	COG0519@1|root,COG0519@2|Bacteria,1NR5X@1224|Proteobacteria,42YTH@68525|delta/epsilon subdivisions,2WUIJ@28221|Deltaproteobacteria,2MPU1@213118|Desulfobacterales	28221|Deltaproteobacteria	F	GMP synthase C terminal domain	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GMP_synt_C,NAD_synthase
XH1_k127_5628254_8	521045.Kole_2050	7.445e-109	371.0	COG4608@1|root,COG4608@2|Bacteria,2GC91@200918|Thermotogae	200918|Thermotogae	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
XH1_k127_5628254_6	1499967.BAYZ01000130_gene2588	7.135e-136	439.0	COG0444@1|root,COG0444@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
XH1_k127_5628254_7	1499967.BAYZ01000130_gene2587	7.487e-131	426.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
XH1_k127_5628254_3	1499967.BAYZ01000129_gene2585	8.184e-162	514.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
XH1_k127_5628254_4	1499967.BAYZ01000129_gene2584	3.911e-160	510.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	ddpA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
XH1_k127_565002_3	186497.PF0024	2.424e-104	353.0	COG2379@1|root,arCOG04170@2157|Archaea,2XSTZ@28890|Euryarchaeota,242J9@183968|Thermococci	183968|Thermococci	G	Glycerate kinase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
XH1_k127_565002_4	304371.MCP_1267	9.381e-62	225.0	COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota,2N9DW@224756|Methanomicrobia	224756|Methanomicrobia	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
XH1_k127_565002_7	1125863.JAFN01000001_gene1709	4.545e-05	51.0	2EQD3@1|root,33HZ5@2|Bacteria,1P9PI@1224|Proteobacteria,433DW@68525|delta/epsilon subdivisions,2WX7R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_565002_6	269799.Gmet_0391	6.122e-21	93.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,42V6T@68525|delta/epsilon subdivisions,2WRAX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
XH1_k127_565002_5	1304284.L21TH_1141	1.784e-28	119.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,36IQS@31979|Clostridiaceae	186801|Clostridia	S	GatB Yqey domain protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
XH1_k127_565002_2	1232410.KI421412_gene99	1.23e-109	383.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2WK5H@28221|Deltaproteobacteria,43RYU@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	ATPase domain of DNA mismatch repair MUTS family	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
XH1_k127_565002_1	439235.Dalk_3077	9.964e-111	378.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,2MHRW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
XH1_k127_565002_0	335543.Sfum_1212	1.883e-113	380.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2MQXV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
XH1_k127_5662202_1	59374.Fisuc_2530	2.105e-21	101.0	2FK00@1|root,34BNB@2|Bacteria	2|Bacteria	S	tigr02147	-	-	-	-	-	-	-	-	-	-	-	-	DUF4423
XH1_k127_5662202_0	96561.Dole_2348	6.943e-96	322.0	COG0507@1|root,COG1948@1|root,COG0507@2|Bacteria,COG1948@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2MINC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
XH1_k127_5662396_4	1242864.D187_001250	4.551e-08	55.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria,2Z0QK@29|Myxococcales	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
XH1_k127_5662396_1	1265845.PWEIH_09853	9.945e-86	307.0	COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H9W1@91061|Bacilli,26JGA@186820|Listeriaceae	91061|Bacilli	O	Pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
XH1_k127_5662396_2	887898.HMPREF0551_0420	6.666e-55	196.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,2VQAY@28216|Betaproteobacteria,1K2NU@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ebsC	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
XH1_k127_5662396_0	909663.KI867150_gene1152	1.371e-140	455.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQU0@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PDZ domain (Also known as DHR or GLGF)	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
XH1_k127_5663319_3	1392502.JNIO01000002_gene605	3.31e-27	126.0	COG1538@1|root,COG1538@2|Bacteria,1TQ0W@1239|Firmicutes,4H3MR@909932|Negativicutes	909932|Negativicutes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
XH1_k127_5663319_1	643648.Slip_1582	9.525e-88	304.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,42JJF@68298|Syntrophomonadaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
XH1_k127_5663319_4	742823.HMPREF9465_00478	2.545e-17	90.0	COG0515@1|root,COG0515@2|Bacteria,1N75K@1224|Proteobacteria,2W05P@28216|Betaproteobacteria,4PQYC@995019|Sutterellaceae	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5663319_0	429009.Adeg_0210	1.999e-105	369.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,42FKG@68295|Thermoanaerobacterales	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
XH1_k127_5663319_2	644966.Tmar_0650	2.308e-49	179.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,3WCT4@538999|Clostridiales incertae sedis	186801|Clostridia	E	Amino acid amide ABC transporter ATP-binding protein 2, HAAT family	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
XH1_k127_5668002_1	179408.Osc7112_0901	5.262e-39	161.0	COG2931@1|root,COG2931@2|Bacteria,1G3AC@1117|Cyanobacteria,1HE4V@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Peptidase C11, clostripain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,HemolysinCabind,Peptidase_C11,VCBS
XH1_k127_5668002_0	1089547.KB913013_gene3086	3.032e-41	169.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,47MWF@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
XH1_k127_5668002_2	1265505.ATUG01000001_gene4575	1.594e-21	101.0	2CD96@1|root,32XZD@2|Bacteria,1N5W5@1224|Proteobacteria,42UZ9@68525|delta/epsilon subdivisions,2WR27@28221|Deltaproteobacteria,2MKNA@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5676656_4	316067.Geob_3287	8.137e-22	101.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,43TTS@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
XH1_k127_5676656_1	760568.Desku_0718	1.693e-72	254.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,261FK@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
XH1_k127_5676656_0	35841.BT1A1_3283	1.459e-142	460.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,1ZBFX@1386|Bacillus	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
XH1_k127_5676656_2	1125863.JAFN01000001_gene496	3.179e-65	231.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
XH1_k127_5676656_3	246194.CHY_1148	8.213e-51	189.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,42ERN@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM peptidase M16 domain protein	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
XH1_k127_5685097_5	1167006.UWK_01421	8.893e-12	74.0	COG5660@1|root,32WII@2|Bacteria,1R3ME@1224|Proteobacteria,43DKX@68525|delta/epsilon subdivisions,2X8S3@28221|Deltaproteobacteria,2MPQM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
XH1_k127_5685097_3	555088.DealDRAFT_0523	6.764e-51	195.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	lysDH	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
XH1_k127_5685097_2	525897.Dbac_0080	3.368e-101	338.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,42QPT@68525|delta/epsilon subdivisions,2WN1M@28221|Deltaproteobacteria,2M987@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM RarD protein, DMT superfamily transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
XH1_k127_5685097_4	1499502.EV12_0158	7.033e-26	109.0	COG3695@1|root,COG3695@2|Bacteria,1G82G@1117|Cyanobacteria,1MN2I@1212|Prochloraceae	1117|Cyanobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
XH1_k127_5685097_1	1125863.JAFN01000001_gene309	1.013e-101	338.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2WJ6C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
XH1_k127_5685097_0	56780.SYN_00521	0.0	1137.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2MR4G@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
XH1_k127_5694262_0	614083.AWQR01000047_gene3258	3.435e-176	557.0	COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,2VN94@28216|Betaproteobacteria,4AF6F@80864|Comamonadaceae	28216|Betaproteobacteria	G	Strictosidine synthase	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2,SGL,Str_synth
XH1_k127_5694262_4	391625.PPSIR1_31478	8.497e-65	229.0	COG0566@1|root,COG0566@2|Bacteria,1Q9ZD@1224|Proteobacteria,42VPG@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	rRNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
XH1_k127_5694262_8	994573.T472_0205565	3.364e-37	142.0	2C539@1|root,33HA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5694262_7	215803.DB30_8320	7.818e-53	200.0	2A6N7@1|root,30VG1@2|Bacteria,1RDJ7@1224|Proteobacteria,42ZWY@68525|delta/epsilon subdivisions,2WVGB@28221|Deltaproteobacteria,2YUK9@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5694262_3	1191523.MROS_2095	3.564e-68	241.0	COG0646@1|root,COG0646@2|Bacteria	2|Bacteria	E	methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
XH1_k127_5694262_1	96561.Dole_2957	7.926e-154	494.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
XH1_k127_5694262_5	96561.Dole_2958	1.863e-64	227.0	COG5012@1|root,COG5012@2|Bacteria,1RBM2@1224|Proteobacteria,42QTX@68525|delta/epsilon subdivisions,2WMRE@28221|Deltaproteobacteria,2MP45@213118|Desulfobacterales	28221|Deltaproteobacteria	S	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
XH1_k127_5694262_2	2754.EH55_00405	1.094e-72	265.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,3TAST@508458|Synergistetes	508458|Synergistetes	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
XH1_k127_5694262_6	1304880.JAGB01000002_gene1616	1.167e-53	196.0	COG1410@1|root,COG1410@2|Bacteria,1V5ZS@1239|Firmicutes,24I4A@186801|Clostridia	186801|Clostridia	E	PFAM Vitamin B12 dependent methionine synthase, activation domain	-	-	-	-	-	-	-	-	-	-	-	-	Met_synt_B12
XH1_k127_5694262_9	96561.Dole_2526	7.661e-28	115.0	COG1024@1|root,COG1024@2|Bacteria,1MW41@1224|Proteobacteria,42N51@68525|delta/epsilon subdivisions,2WKBV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_5694681_4	177439.DP2064	5.187e-48	175.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,42QEX@68525|delta/epsilon subdivisions,2WMFU@28221|Deltaproteobacteria,2MIVK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Phosphotransferase enzyme family	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
XH1_k127_5694681_5	1047013.AQSP01000108_gene2068	1.001e-32	130.0	COG0724@1|root,COG0724@2|Bacteria,2NPT0@2323|unclassified Bacteria	2|Bacteria	S	RNA recognition motif	rpbA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
XH1_k127_5694681_1	706587.Desti_2873	1.519e-88	306.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
XH1_k127_5694681_0	1121405.dsmv_0256	5.607e-122	402.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
XH1_k127_5694681_3	459495.SPLC1_S171240	1.034e-49	188.0	COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria	1117|Cyanobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
XH1_k127_5694681_2	941449.dsx2_0937	3.867e-77	264.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2M8BZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM transferase hexapeptide repeat containing protein	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
XH1_k127_5702485_0	1121405.dsmv_1959	1.483e-92	312.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2MN8E@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
XH1_k127_5702485_2	1121396.KB893123_gene1103	2.004e-53	200.0	COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,42PQN@68525|delta/epsilon subdivisions,2WKV7@28221|Deltaproteobacteria,2MJFP@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
XH1_k127_5702485_6	297246.lpp1747	2.624e-06	58.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1JD9X@118969|Legionellales	118969|Legionellales	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	fleN	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	ParA
XH1_k127_5702485_1	1127696.HMPREF9134_00737	4.639e-58	216.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,2FMX2@200643|Bacteroidia,22W77@171551|Porphyromonadaceae	976|Bacteroidetes	D	Chromosome partitioning protein ParA	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
XH1_k127_5702485_5	1038859.AXAU01000011_gene2414	7.176e-14	77.0	COG3070@1|root,COG3070@2|Bacteria,1P6Z6@1224|Proteobacteria	1224|Proteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
XH1_k127_5702485_3	909663.KI867150_gene391	4.584e-51	187.0	COG1633@1|root,COG1633@2|Bacteria,1NG4N@1224|Proteobacteria,42W3T@68525|delta/epsilon subdivisions,2WREZ@28221|Deltaproteobacteria,2MRRS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_5702485_4	177437.HRM2_27280	9.41e-39	149.0	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2MIS0@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3,VWA,VWA_2
XH1_k127_571285_6	935948.KE386495_gene2134	1.243e-34	142.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,42F4T@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
XH1_k127_571285_8	56780.SYN_02965	8.579e-23	102.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42UFU@68525|delta/epsilon subdivisions,2WR59@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
XH1_k127_571285_3	1232410.KI421424_gene1634	1.509e-45	181.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,42P6A@68525|delta/epsilon subdivisions,2WJZ4@28221|Deltaproteobacteria,43U4U@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,dCache_1
XH1_k127_571285_1	56780.SYN_00607	6.626e-106	350.0	COG0543@1|root,COG0543@2|Bacteria,1NTWI@1224|Proteobacteria,42M66@68525|delta/epsilon subdivisions,2WJJ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	nfnB	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
XH1_k127_571285_0	56780.SYN_00606	7.259e-221	693.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MREN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
XH1_k127_571285_5	574087.Acear_1814	3.881e-35	137.0	COG4109@1|root,COG4109@2|Bacteria,1VA3T@1239|Firmicutes,24MQM@186801|Clostridia,3WBYX@53433|Halanaerobiales	186801|Clostridia	K	PFAM DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
XH1_k127_571285_7	439235.Dalk_0995	2.444e-24	106.0	COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,42VB5@68525|delta/epsilon subdivisions,2WRJD@28221|Deltaproteobacteria,2MKVP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM FlhB HrpN YscU SpaS Family	-	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
XH1_k127_571285_4	439235.Dalk_0311	6.934e-43	161.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,42TQF@68525|delta/epsilon subdivisions,2WQHJ@28221|Deltaproteobacteria,2MKRY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
XH1_k127_571285_2	439235.Dalk_0312	1.176e-102	347.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,42P08@68525|delta/epsilon subdivisions,2WJXV@28221|Deltaproteobacteria,2MI0F@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
XH1_k127_5722365_1	1042156.CXIVA_14570	2.015e-103	346.0	COG2006@1|root,COG2006@2|Bacteria,1TRX2@1239|Firmicutes,249GX@186801|Clostridia,36GCZ@31979|Clostridiaceae	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_10,Fer4_7
XH1_k127_5722365_2	637390.AFOH01000139_gene1201	1.201e-11	67.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1SCYV@1236|Gammaproteobacteria,2ND6G@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
XH1_k127_5722365_0	1380387.JADM01000017_gene3436	6.477e-178	576.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria	1224|Proteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
XH1_k127_5727514_0	246197.MXAN_5124	3.242e-130	430.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42PH1@68525|delta/epsilon subdivisions,2WKMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	mrpB	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_5727514_1	880072.Desac_2882	9.015e-68	259.0	COG2203@1|root,COG3829@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
XH1_k127_5729277_0	1297742.A176_03654	2.771e-111	388.0	COG0457@1|root,COG1729@1|root,COG3063@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	2.7.11.1	ko:K12132,ko:K20543	-	-	-	-	ko00000,ko01000,ko01001,ko02000	1.B.55.3	-	-	Pkinase,TPR_12,TPR_16,TPR_19,TPR_6,TPR_8,YfiO
XH1_k127_5729277_1	215803.DB30_2717	8.946e-44	179.0	COG0457@1|root,COG0457@2|Bacteria,1PC4W@1224|Proteobacteria,438IM@68525|delta/epsilon subdivisions,2X3TG@28221|Deltaproteobacteria,2YX2F@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5729277_2	215803.DB30_2719	2.458e-26	126.0	COG1716@1|root,COG1716@2|Bacteria,1Q2U2@1224|Proteobacteria,438G9@68525|delta/epsilon subdivisions,2X3R3@28221|Deltaproteobacteria,2YWWA@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
XH1_k127_5733041_2	1042876.PPS_0156	6.051e-09	59.0	2DRGE@1|root,33BM1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5733041_0	96561.Dole_2545	5.049e-164	525.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,42PNR@68525|delta/epsilon subdivisions,2WK3I@28221|Deltaproteobacteria,2MIUM@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S double cluster binding domain	yjeS	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
XH1_k127_5733041_1	1211035.CD30_09390	1.303e-38	151.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,3IX1P@400634|Lysinibacillus	91061|Bacilli	P	ATP synthase subunit J	ktrB1	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
XH1_k127_5757692_4	439235.Dalk_0298	4.339e-14	75.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK05@28221|Deltaproteobacteria,2MHS3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
XH1_k127_5757692_3	70601.3257265	2.6e-40	153.0	COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci	183968|Thermococci	J	Endoribonuclease L-PSP	-	GO:0003674,GO:0003824,GO:0016787,GO:0019239	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
XH1_k127_5757692_1	338966.Ppro_0982	3.256e-79	271.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
XH1_k127_5757692_2	215803.DB30_4458	3.444e-73	258.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,2YU4X@29|Myxococcales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
XH1_k127_5757692_0	1499967.BAYZ01000009_gene5298	1.202e-138	458.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
XH1_k127_5767093_2	439235.Dalk_4685	2.219e-13	72.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria	1224|Proteobacteria	C	PFAM CoA-binding domain protein	MA20_15065	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
XH1_k127_5767093_0	880072.Desac_1569	5.214e-78	271.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,43DN9@68525|delta/epsilon subdivisions,2X25J@28221|Deltaproteobacteria,2MS0P@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
XH1_k127_5767093_1	56780.SYN_02176	2.574e-77	268.0	COG1032@1|root,COG1032@2|Bacteria,1R4XI@1224|Proteobacteria,42NPM@68525|delta/epsilon subdivisions,2WJK2@28221|Deltaproteobacteria,2MQ6Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
XH1_k127_5767735_8	1382304.JNIL01000001_gene2865	5.58e-27	112.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,278ZG@186823|Alicyclobacillaceae	91061|Bacilli	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
XH1_k127_5767735_5	699218.HMPREF0889_0414	6.401e-45	169.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4H4NK@909932|Negativicutes	909932|Negativicutes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
XH1_k127_5767735_9	574087.Acear_0257	1.224e-24	107.0	COG1516@1|root,COG1516@2|Bacteria,1VA8K@1239|Firmicutes,24MRW@186801|Clostridia,3WAV1@53433|Halanaerobiales	186801|Clostridia	N	TIGRFAM flagellar biosynthetic protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
XH1_k127_5767735_0	1125863.JAFN01000001_gene2171	5.164e-122	402.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
XH1_k127_5767735_2	706587.Desti_3629	1.369e-54	196.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2MQHK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
XH1_k127_5767735_6	335543.Sfum_2991	4.34e-36	143.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria,2MRXR@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
XH1_k127_5767735_1	414684.RC1_3094	2.99e-66	233.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2TTB3@28211|Alphaproteobacteria,2JRPW@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
XH1_k127_5767735_4	1449126.JQKL01000035_gene2162	1.965e-46	175.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,2691D@186813|unclassified Clostridiales	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
XH1_k127_5767735_7	1123371.ATXH01000001_gene1256	4.033e-30	121.0	COG2052@1|root,COG2052@2|Bacteria,2GHYU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Belongs to the UPF0296 family	-	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
XH1_k127_5767735_3	485916.Dtox_2320	7.584e-49	184.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,2617V@186807|Peptococcaceae	186801|Clostridia	S	PFAM YicC-like family, N-terminal region	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
XH1_k127_5781483_0	56780.SYN_01447	6.108e-216	682.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2MQIA@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the transketolase family	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
XH1_k127_5781483_1	945713.IALB_1964	2.428e-99	331.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	1.1.1.343,1.1.1.44,2.2.1.2,3.1.26.12,5.3.1.9	ko:K00033,ko:K00616,ko:K01810,ko:K08300,ko:K13810	ko00010,ko00030,ko00480,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,map00010,map00030,map00480,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230,map03018	M00001,M00004,M00006,M00007,M00114,M00394	R01528,R01827,R02739,R02740,R03321,R10221	RC00001,RC00376,RC00439,RC00539,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019,ko04147	-	-	-	PGI,TAL_FSA
XH1_k127_5793721_1	880073.Calab_0526	1.16e-62	233.0	COG1404@1|root,COG3291@1|root,COG3386@1|root,COG5276@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17,3.2.1.4	ko:K01053,ko:K01179,ko:K07214,ko:K12287	ko00030,ko00053,ko00500,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00500,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751,R06200,R11307,R11308	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko02044,ko04147	-	GH5,GH9	-	Big_5,DUF285,Esterase,He_PIG,SGL
XH1_k127_5793721_3	1167006.UWK_02684	8.499e-07	57.0	COG0457@1|root,COG1225@1|root,COG1462@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,COG1462@2|Bacteria,1NK5T@1224|Proteobacteria	1224|Proteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
XH1_k127_5793721_0	1167006.UWK_02684	2.52e-182	593.0	COG0457@1|root,COG1225@1|root,COG1462@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,COG1462@2|Bacteria,1NK5T@1224|Proteobacteria	1224|Proteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
XH1_k127_5793721_2	666685.R2APBS1_1791	2.605e-17	86.0	2CKE6@1|root,32ZEV@2|Bacteria,1NBRM@1224|Proteobacteria,1SCY3@1236|Gammaproteobacteria,1X8E5@135614|Xanthomonadales	135614|Xanthomonadales	S	Family of unknown function (DUF5329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5329
XH1_k127_580110_4	96561.Dole_1068	1.608e-62	217.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,2MI15@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
XH1_k127_580110_3	1123257.AUFV01000001_gene1518	1.732e-85	303.0	COG1574@1|root,COG1574@2|Bacteria	2|Bacteria	G	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
XH1_k127_580110_1	96561.Dole_1070	6.054e-169	545.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,42MZ8@68525|delta/epsilon subdivisions,2WMM3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
XH1_k127_580110_2	96561.Dole_1071	6.44e-130	426.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,42MZ8@68525|delta/epsilon subdivisions,2WMM3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
XH1_k127_580110_5	96561.Dole_1067	2.621e-44	168.0	COG1309@1|root,COG5096@1|root,COG1309@2|Bacteria,COG5096@2|Bacteria,1PKJU@1224|Proteobacteria,42X0G@68525|delta/epsilon subdivisions,2WTHN@28221|Deltaproteobacteria,2MNMP@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
XH1_k127_580110_0	439235.Dalk_3858	4.863e-175	561.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2MI1Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
XH1_k127_580110_6	643648.Slip_1426	5.124e-22	101.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,42JPK@68298|Syntrophomonadaceae	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
XH1_k127_580827_4	439235.Dalk_3648	2.902e-15	75.0	2CH8U@1|root,31KG8@2|Bacteria,1PAYR@1224|Proteobacteria	1224|Proteobacteria	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
XH1_k127_580827_2	1121405.dsmv_1250	5.672e-77	261.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42RB9@68525|delta/epsilon subdivisions,2WMPE@28221|Deltaproteobacteria,2MJPY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ferritin-like domain	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
XH1_k127_580827_1	1232437.KL661969_gene4964	9.675e-84	284.0	COG3910@1|root,COG3910@2|Bacteria,1MZSY@1224|Proteobacteria,42R25@68525|delta/epsilon subdivisions,2WN2C@28221|Deltaproteobacteria,2MJIF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
XH1_k127_580827_5	247490.KSU1_C0280	9.379e-11	74.0	2BRMQ@1|root,32KM4@2|Bacteria,2J4AR@203682|Planctomycetes	247490.KSU1_C0280|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_580827_6	156978.CIMIT_00615	0.0002477	48.0	COG4932@1|root,COG4932@2|Bacteria,2HQGK@201174|Actinobacteria,22Q6J@1653|Corynebacteriaceae	201174|Actinobacteria	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
XH1_k127_580827_0	525897.Dbac_1357	3.224e-86	301.0	COG3437@1|root,COG3437@2|Bacteria,1QW6V@1224|Proteobacteria	1224|Proteobacteria	KT	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	MA20_23615	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,PilZ,Response_reg
XH1_k127_580827_3	395963.Bind_1808	6.911e-17	84.0	COG1226@1|root,32Y28@2|Bacteria,1NEAT@1224|Proteobacteria,2U33B@28211|Alphaproteobacteria,3NBAR@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
XH1_k127_5818918_0	56780.SYN_02149	4.174e-122	405.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,2MQ4C@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
XH1_k127_5818918_1	1415754.JQMK01000002_gene2698	5.157e-10	63.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,4689X@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	COG4968 Tfp pilus assembly protein PilE	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
XH1_k127_5821382_5	1484158.PSNIH1_09320	3.894e-19	91.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,3VZM7@53335|Pantoea	1236|Gammaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_0282,ic_1306.c0493	F420_oxidored,P5CR_dimer
XH1_k127_5821382_3	1379281.AVAG01000063_gene1125	5.519e-54	199.0	COG0457@1|root,COG0457@2|Bacteria,1R51F@1224|Proteobacteria,42NP1@68525|delta/epsilon subdivisions,2WMJ3@28221|Deltaproteobacteria,2M8AE@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
XH1_k127_5821382_1	340099.Teth39_0710	3.273e-112	377.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,42FF6@68295|Thermoanaerobacterales	186801|Clostridia	L	AAA ATPase, central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
XH1_k127_5821382_2	247490.KSU1_C0327	1.75e-90	314.0	COG4284@1|root,COG4284@2|Bacteria,2IX7M@203682|Planctomycetes	203682|Planctomycetes	G	UDP-glucose pyrophosphorylase	-	-	2.7.7.23,2.7.7.83	ko:K00972	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
XH1_k127_5821382_4	1379698.RBG1_1C00001G0015	2.357e-52	209.0	COG0840@1|root,COG4191@1|root,COG0840@2|Bacteria,COG4191@2|Bacteria,2NPGF@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.4.1.12,2.7.13.3,3.1.3.3	ko:K00694,ko:K03406,ko:K07315,ko:K14986	ko00500,ko01100,ko02020,ko02026,ko02030,map00500,map01100,map02020,map02026,map02030	M00524	R02889	RC00005	ko00000,ko00001,ko00002,ko01000,ko01001,ko01003,ko02000,ko02022,ko02035,ko03021	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,HATPase_c,HisKA,NIT,PAS,PAS_4,PAS_9
XH1_k127_5821382_0	744872.Spica_1509	3.874e-135	443.0	COG2204@1|root,COG2204@2|Bacteria,2J5NY@203691|Spirochaetes	203691|Spirochaetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	rrp-2	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_5840111_1	880072.Desac_2719	1.023e-145	491.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MQA8@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
XH1_k127_5840111_4	338966.Ppro_3016	6.071e-68	237.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,43SYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
XH1_k127_5840111_2	56780.SYN_00923	1.02e-106	359.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MQRN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
XH1_k127_5840111_0	1379281.AVAG01000017_gene1004	6.846e-186	599.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,2M7Z9@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
XH1_k127_5840111_8	648996.Theam_0108	7.197e-18	91.0	COG2078@1|root,COG2078@2|Bacteria,2G44K@200783|Aquificae	200783|Aquificae	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
XH1_k127_5840111_6	698769.JFBD01000083_gene43	2.341e-33	139.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	gph3	-	3.1.3.18	ko:K01091,ko:K07025	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
XH1_k127_5840111_7	706587.Desti_4658	1.804e-21	108.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria,2MQYJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
XH1_k127_5840111_10	1410632.JHWW01000012_gene52	5.876e-05	49.0	COG2747@1|root,COG2747@2|Bacteria,1VFH9@1239|Firmicutes,24QZ8@186801|Clostridia,27PGN@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Anti-sigma-28 factor, FlgM	flgM	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
XH1_k127_5840111_5	1121438.JNJA01000002_gene3805	1.132e-41	162.0	COG4786@1|root,COG4786@2|Bacteria,1PZ24@1224|Proteobacteria,42NGI@68525|delta/epsilon subdivisions,2WMR8@28221|Deltaproteobacteria,2M95D@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgF	-	-	ko:K02391,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
XH1_k127_5840111_3	1121448.DGI_0522	7.464e-96	320.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,42N3R@68525|delta/epsilon subdivisions,2WJDN@28221|Deltaproteobacteria,2M806@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
XH1_k127_5840111_9	1298593.TOL_2597	4.173e-07	61.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,1XM5S@135619|Oceanospirillales	135619|Oceanospirillales	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	-	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
XH1_k127_5843141_4	439235.Dalk_0295	6.379e-56	201.0	COG1406@1|root,COG1406@2|Bacteria,1RATZ@1224|Proteobacteria,42R2Q@68525|delta/epsilon subdivisions,2WP6F@28221|Deltaproteobacteria,2MJQ2@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
XH1_k127_5843141_5	1499967.BAYZ01000095_gene4055	2.701e-51	187.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
XH1_k127_5843141_3	177437.HRM2_13230	1.8e-83	291.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2MHWK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
XH1_k127_5843141_1	1499967.BAYZ01000028_gene1264	7.503e-128	416.0	COG1181@1|root,COG1181@2|Bacteria,2NRF0@2323|unclassified Bacteria	2|Bacteria	M	ATP-grasp domain	ddlA	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
XH1_k127_5843141_0	1499967.BAYZ01000028_gene1265	9.632e-169	540.0	COG1509@1|root,COG1509@2|Bacteria,2NNY6@2323|unclassified Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA	-	5.4.3.2	ko:K01843,ko:K19810	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
XH1_k127_5843141_2	909663.KI867150_gene1014	5.243e-107	360.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,42PK1@68525|delta/epsilon subdivisions,2WJ65@28221|Deltaproteobacteria,2MQ6M@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
XH1_k127_5843141_6	888833.HMPREF9421_1011	4.693e-25	107.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli	91061|Bacilli	V	ABC transporter, ATP-binding protein	salX	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_5864088_3	1236497.BAJQ01000024_gene2541	6.379e-60	218.0	COG0578@1|root,COG0578@2|Bacteria,4NJ15@976|Bacteroidetes,2FR3V@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
XH1_k127_5864088_0	671143.DAMO_1541	1.559e-127	421.0	COG1215@1|root,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
XH1_k127_5864088_2	349521.HCH_06804	3.904e-62	224.0	2DC00@1|root,2ZC4V@2|Bacteria,1RBPR@1224|Proteobacteria,1S2KT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5864088_1	269799.Gmet_3529	1.186e-78	276.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42T4H@68525|delta/epsilon subdivisions,2WPIT@28221|Deltaproteobacteria,43U0U@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
XH1_k127_5864088_4	883.DvMF_2080	5.144e-42	163.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
XH1_k127_5901318_1	1499967.BAYZ01000150_gene1718	3.74e-124	400.0	COG4912@1|root,COG4912@2|Bacteria,2NRX9@2323|unclassified Bacteria	2|Bacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
XH1_k127_5901318_0	439235.Dalk_1136	1.747e-155	508.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WUG9@28221|Deltaproteobacteria,2MMW2@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_5901318_6	555088.DealDRAFT_2092	1.034e-18	89.0	COG1143@1|root,COG1143@2|Bacteria,1UI0U@1239|Firmicutes,25E9M@186801|Clostridia,42KNQ@68298|Syntrophomonadaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
XH1_k127_5901318_2	439235.Dalk_2968	7.187e-123	402.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2MPWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM NAD dependent epimerase dehydratase family	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
XH1_k127_5901318_3	96561.Dole_1881	2.228e-88	300.0	COG0204@1|root,COG0204@2|Bacteria,1NCW0@1224|Proteobacteria,42SG7@68525|delta/epsilon subdivisions,2X6VZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
XH1_k127_5901318_4	439235.Dalk_2039	1.801e-76	265.0	COG0300@1|root,COG0300@2|Bacteria,1R9VQ@1224|Proteobacteria,42SRD@68525|delta/epsilon subdivisions,2WPTU@28221|Deltaproteobacteria,2MMT8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
XH1_k127_5901318_5	439235.Dalk_2036	9.151e-23	99.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MIAR@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
XH1_k127_5927826_0	1121405.dsmv_2054	2.928e-102	338.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2MJR3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
XH1_k127_5927826_1	335543.Sfum_3194	5.496e-41	159.0	COG5553@1|root,COG5553@2|Bacteria,1NI0U@1224|Proteobacteria,43160@68525|delta/epsilon subdivisions,2WWEA@28221|Deltaproteobacteria,2MS6U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5932858_8	1304888.ATWF01000002_gene347	2.294e-31	136.0	2AAGD@1|root,30ZTD@2|Bacteria,2GFTV@200930|Deferribacteres	200930|Deferribacteres	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5932858_1	404589.Anae109_0166	4.628e-136	448.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2YUC2@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
XH1_k127_5932858_9	1313304.CALK_0374	9.808e-10	67.0	COG3807@1|root,COG3807@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	ygiM	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	Peptidase_M15,SH3_3,SH3_4,VanY,YkuD
XH1_k127_5932858_4	670487.Ocepr_0388	4.694e-70	248.0	COG1171@1|root,COG1171@2|Bacteria,1WI3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
XH1_k127_5932858_3	96561.Dole_1391	6.603e-122	398.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MJ2R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
XH1_k127_5932858_0	96561.Dole_1392	4.498e-173	550.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MJ3H@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
XH1_k127_5932858_7	96561.Dole_1393	2.23e-40	151.0	COG1144@1|root,COG1144@2|Bacteria,1N99V@1224|Proteobacteria,42V8C@68525|delta/epsilon subdivisions,2WRCP@28221|Deltaproteobacteria,2MMCF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
XH1_k127_5932858_5	96561.Dole_1394	4.6e-63	222.0	COG1014@1|root,COG1014@2|Bacteria,1N0EJ@1224|Proteobacteria,42UN6@68525|delta/epsilon subdivisions,2WQCE@28221|Deltaproteobacteria,2MNXX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
XH1_k127_5932858_6	1125863.JAFN01000001_gene2653	1.443e-42	169.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WPGK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
XH1_k127_5932858_10	795359.TOPB45_1537	1.301e-09	68.0	2DQ2P@1|root,334I3@2|Bacteria,2GHBP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
XH1_k127_5932858_2	1415778.JQMM01000001_gene705	1.132e-127	430.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1J4N3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
XH1_k127_5979647_3	1121439.dsat_2350	0.0007318	42.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42RB9@68525|delta/epsilon subdivisions,2WMPE@28221|Deltaproteobacteria,2MB1R@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
XH1_k127_5979647_0	1121440.AUMA01000006_gene1530	2.778e-176	567.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2M91Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
XH1_k127_5979647_1	926566.Terro_1519	7.532e-85	298.0	COG0379@1|root,COG0379@2|Bacteria,3Y328@57723|Acidobacteria,2JHY8@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
XH1_k127_5979647_2	357808.RoseRS_0439	1.573e-34	135.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,375H1@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
XH1_k127_5993327_8	502025.Hoch_3223	3.023e-11	77.0	COG0642@1|root,COG0642@2|Bacteria,1QX5P@1224|Proteobacteria,43BYA@68525|delta/epsilon subdivisions,2X796@28221|Deltaproteobacteria,2Z3E9@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
XH1_k127_5993327_7	335541.Swol_2483	3.276e-45	186.0	COG2199@1|root,COG2202@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,42KYY@68298|Syntrophomonadaceae	186801|Clostridia	T	Diguanylate cyclase with PAS PAC sensor	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS_3,PAS_4
XH1_k127_5993327_6	439235.Dalk_2411	4.173e-49	181.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2MJT1@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
XH1_k127_5993327_5	373903.Hore_02430	8.244e-51	191.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WA5W@53433|Halanaerobiales	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
XH1_k127_5993327_1	340099.Teth39_0215	1.577e-112	384.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,42FCI@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA polymerase	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
XH1_k127_5993327_3	243231.GSU2568	1.819e-80	283.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,43TX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	SMART Elongator protein 3 MiaB NifB	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
XH1_k127_5993327_0	330214.NIDE2906	5.827e-116	391.0	COG0297@1|root,COG0297@2|Bacteria,3J0DJ@40117|Nitrospirae	40117|Nitrospirae	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
XH1_k127_5993327_4	1121405.dsmv_0373	5.015e-79	282.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2MHNX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
XH1_k127_5993327_2	706587.Desti_1526	4.43e-90	305.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42MN3@68525|delta/epsilon subdivisions,2WMHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
XH1_k127_6000853_3	439235.Dalk_1725	2.902e-22	97.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42QI1@68525|delta/epsilon subdivisions,2WMJR@28221|Deltaproteobacteria,2MMRG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
XH1_k127_6000853_2	439235.Dalk_1726	3.212e-106	353.0	COG1703@1|root,COG1703@2|Bacteria,1R44P@1224|Proteobacteria,43B1C@68525|delta/epsilon subdivisions,2X6FJ@28221|Deltaproteobacteria,2MPHZ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
XH1_k127_6000853_0	439235.Dalk_1727	2.818e-178	572.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,43B26@68525|delta/epsilon subdivisions,2X6G6@28221|Deltaproteobacteria,2MKC2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
XH1_k127_6000853_1	439235.Dalk_2202	4.532e-111	367.0	COG1180@1|root,COG1180@2|Bacteria,1QJHU@1224|Proteobacteria,42R2E@68525|delta/epsilon subdivisions,2WMYN@28221|Deltaproteobacteria,2MMZ6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
XH1_k127_6018302_5	246194.CHY_0055	3.888e-63	226.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,42F0X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
XH1_k127_6018302_0	56780.SYN_00664	5.168e-255	797.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	EF-hand_7,Pyridoxal_deC
XH1_k127_6018302_1	1125863.JAFN01000001_gene2044	1.749e-201	645.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
XH1_k127_6018302_10	1122222.AXWR01000019_gene2702	2.222e-21	99.0	COG0517@1|root,COG0517@2|Bacteria,1WMQJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
XH1_k127_6018302_9	237368.SCABRO_04002	5.397e-23	113.0	COG3343@1|root,COG4733@1|root,COG3343@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	DUF285,PA14,TSP_3,VCBS,fn3
XH1_k127_6018302_3	1125863.JAFN01000001_gene1341	8.312e-81	278.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
XH1_k127_6018302_2	1121405.dsmv_0962	3.954e-149	488.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MHS8@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
XH1_k127_6018302_7	706587.Desti_4871	2.914e-27	115.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria,2MQKT@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
XH1_k127_6018302_4	1123371.ATXH01000033_gene416	1.985e-71	247.0	COG0343@1|root,COG0343@2|Bacteria,2GHKI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
XH1_k127_6018302_6	316067.Geob_3451	2.839e-59	211.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,43TNC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
XH1_k127_6018302_8	292459.STH1165	2.053e-25	106.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
XH1_k127_6051453_2	909663.KI867150_gene919	2.982e-41	155.0	COG0748@1|root,COG0748@2|Bacteria,1N2JV@1224|Proteobacteria,42TYW@68525|delta/epsilon subdivisions,2WQEM@28221|Deltaproteobacteria,2MQHZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
XH1_k127_6051453_1	909663.KI867150_gene2625	1.909e-83	285.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria,2MRBY@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
XH1_k127_6051453_0	909663.KI867150_gene2624	2.411e-89	301.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria,2MRH2@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
XH1_k127_6057143_2	338966.Ppro_2150	7.884e-05	45.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42NRK@68525|delta/epsilon subdivisions,2WIM6@28221|Deltaproteobacteria,43TAV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
XH1_k127_6057143_0	439235.Dalk_1689	5.513e-159	535.0	COG2202@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria,2MI6S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,Response_reg
XH1_k127_6057143_1	236814.IX39_11995	2.878e-54	196.0	COG5184@1|root,COG5184@2|Bacteria,4NIP4@976|Bacteroidetes,1IIHQ@117743|Flavobacteriia,3ZNMC@59732|Chryseobacterium	976|Bacteroidetes	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,RCC1
XH1_k127_6061709_1	485915.Dret_0478	7.304e-84	284.0	COG0765@1|root,COG0765@2|Bacteria,1R4RU@1224|Proteobacteria,42PW7@68525|delta/epsilon subdivisions,2WK9J@28221|Deltaproteobacteria,2M8W2@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
XH1_k127_6061709_2	931627.MycrhDRAFT_2770	2.762e-12	72.0	COG1454@1|root,COG1454@2|Bacteria,2ISGP@201174|Actinobacteria	201174|Actinobacteria	C	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
XH1_k127_6061709_0	439235.Dalk_2100	1.357e-112	368.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_6080747_1	1379270.AUXF01000003_gene3763	1.333e-23	111.0	COG5616@1|root,COG5616@2|Bacteria,1ZTN3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidoglycan-synthase activator LpoB	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
XH1_k127_6080747_2	641526.ADIWIN_1563	2.102e-06	60.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
XH1_k127_6080747_0	56780.SYN_00029	7.967e-43	162.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2MRYF@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
XH1_k127_60970_3	452662.SJA_C1-13960	1.173e-15	85.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria,2K3PM@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
XH1_k127_60970_0	96561.Dole_0559	3.876e-140	458.0	COG1541@1|root,COG1541@2|Bacteria,1R79E@1224|Proteobacteria,42NRJ@68525|delta/epsilon subdivisions,2WKGW@28221|Deltaproteobacteria,2MN0U@213118|Desulfobacterales	28221|Deltaproteobacteria	H	phenylacetate-CoA ligase Coenzyme F390 synthetase-like protein	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
XH1_k127_60970_1	1121422.AUMW01000014_gene1314	1.687e-46	177.0	COG4739@1|root,COG4739@2|Bacteria	2|Bacteria	S	Uncharacterized protein containing a ferredoxin domain (DUF2148)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2148
XH1_k127_60970_2	1121422.AUMW01000014_gene1313	1.092e-43	164.0	COG4739@1|root,COG4739@2|Bacteria	2|Bacteria	S	Uncharacterized protein containing a ferredoxin domain (DUF2148)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2148
XH1_k127_614815_6	338963.Pcar_2076	4.986e-40	153.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42MCS@68525|delta/epsilon subdivisions,2WQGI@28221|Deltaproteobacteria,43V4U@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
XH1_k127_614815_7	1121403.AUCV01000052_gene2567	4.366e-27	122.0	COG2197@1|root,COG2197@2|Bacteria,1R3YQ@1224|Proteobacteria,42N0Q@68525|delta/epsilon subdivisions,2WM6W@28221|Deltaproteobacteria,2MIJG@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_4,PAS_9
XH1_k127_614815_9	1304877.KI519399_gene1963	0.000243	52.0	COG0784@1|root,COG4191@1|root,COG5000@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3JTQS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
XH1_k127_614815_0	1304872.JAGC01000009_gene1370	1.13e-164	527.0	COG2309@1|root,COG2309@2|Bacteria,1MW2Y@1224|Proteobacteria,42P6P@68525|delta/epsilon subdivisions,2WJF8@28221|Deltaproteobacteria,2M90N@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
XH1_k127_614815_1	1200792.AKYF01000027_gene663	8.689e-134	435.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HA76@91061|Bacilli,26U4M@186822|Paenibacillaceae	91061|Bacilli	CE	Isocitrate/isopropylmalate dehydrogenase	ycsA	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
XH1_k127_614815_8	1121396.KB892935_gene3864	1.415e-22	106.0	COG2199@1|root,COG4191@1|root,COG3706@2|Bacteria,COG4191@2|Bacteria,1NCEB@1224|Proteobacteria,42ZMD@68525|delta/epsilon subdivisions,2WV10@28221|Deltaproteobacteria,2MNDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_614815_5	1232410.KI421415_gene3099	1.291e-41	162.0	COG2199@1|root,COG2770@1|root,COG3829@1|root,COG2199@2|Bacteria,COG2770@2|Bacteria,COG3829@2|Bacteria,1RGCV@1224|Proteobacteria,42U0K@68525|delta/epsilon subdivisions,2WQRW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
XH1_k127_614815_2	439235.Dalk_0422	2.175e-100	336.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,42S0M@68525|delta/epsilon subdivisions,2WNYE@28221|Deltaproteobacteria,2MMEA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	yheT	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6
XH1_k127_614815_4	1304885.AUEY01000036_gene2241	3.455e-85	289.0	COG1024@1|root,COG1024@2|Bacteria,1RIVB@1224|Proteobacteria,42PMV@68525|delta/epsilon subdivisions,2WKCQ@28221|Deltaproteobacteria,2MHM8@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_614815_3	443143.GM18_2270	1.692e-85	297.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
XH1_k127_6174338_1	439235.Dalk_5083	3.744e-68	248.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria	1224|Proteobacteria	P	PFAM Phosphate-selective porin O	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
XH1_k127_6174338_0	439235.Dalk_5084	1.7e-97	328.0	COG2041@1|root,COG2041@2|Bacteria,1NS6T@1224|Proteobacteria,42YA7@68525|delta/epsilon subdivisions,2WTM5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6174399_0	690850.Desaf_1234	4.121e-163	526.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M915@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
XH1_k127_6174399_1	697281.Mahau_0439	7.291e-136	446.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,42EW9@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
XH1_k127_6218000_2	283942.IL1987	4.75e-18	93.0	COG1519@1|root,COG3642@1|root,COG1519@2|Bacteria,COG3642@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,2QFMF@267893|Idiomarinaceae	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdtA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417	Glycos_transf_1,Glycos_transf_N
XH1_k127_6218000_0	335543.Sfum_0871	7.092e-69	243.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
XH1_k127_6218000_1	1499967.BAYZ01000041_gene2396	9.495e-21	96.0	2ETAJ@1|root,33KUH@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
XH1_k127_6221828_4	335543.Sfum_2554	4.591e-08	61.0	COG4967@1|root,COG4967@2|Bacteria,1NI49@1224|Proteobacteria,42X6W@68525|delta/epsilon subdivisions,2WSY4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
XH1_k127_6221828_3	1121396.KB893057_gene2528	3.029e-10	70.0	COG4966@1|root,COG4966@2|Bacteria,1N2NR@1224|Proteobacteria,42TRJ@68525|delta/epsilon subdivisions,2WQQ2@28221|Deltaproteobacteria,2MKHU@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	pilus assembly protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,PilW
XH1_k127_6221828_5	1117315.AHCA01000004_gene672	1.456e-06	57.0	COG4970@1|root,COG4970@2|Bacteria,1N43I@1224|Proteobacteria,1SBWS@1236|Gammaproteobacteria,2Q334@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	NU	COG4970 Tfp pilus assembly protein FimT	-	-	-	ko:K08084,ko:K08085	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
XH1_k127_6221828_1	671143.DAMO_0319	1.758e-69	263.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2NP4I@2323|unclassified Bacteria	2|Bacteria	U	Metallo-beta-lactamase superfamily	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
XH1_k127_6221828_0	273068.TTE1530	4.677e-95	320.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,42FGV@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
XH1_k127_6221828_2	429009.Adeg_0374	1.051e-44	173.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,42GEQ@68295|Thermoanaerobacterales	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
XH1_k127_6232551_1	903818.KI912269_gene422	3.245e-180	569.0	COG0017@1|root,COG0017@2|Bacteria	2|Bacteria	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2
XH1_k127_6232551_6	926566.Terro_0598	3.997e-28	113.0	COG1278@1|root,COG1278@2|Bacteria,3Y5NU@57723|Acidobacteria	57723|Acidobacteria	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
XH1_k127_6232551_2	96561.Dole_0567	5.872e-139	472.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2MI1W@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
XH1_k127_6232551_5	933262.AXAM01000040_gene1228	1.213e-46	170.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2MK8A@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
XH1_k127_6232551_4	706587.Desti_3603	1.092e-80	273.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
XH1_k127_6232551_3	1123371.ATXH01000009_gene1091	4.146e-85	285.0	COG0004@1|root,COG0004@2|Bacteria,2GH8U@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
XH1_k127_6232551_0	56780.SYN_01633	6.967e-209	659.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MQVH@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
XH1_k127_6233665_2	56780.SYN_00343	3.657e-90	304.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2WJFH@28221|Deltaproteobacteria,2MQCU@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
XH1_k127_6233665_3	909663.KI867150_gene1429	6.173e-63	218.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
XH1_k127_6233665_0	1131462.DCF50_p189	4.819e-126	416.0	COG0535@1|root,COG0535@2|Bacteria,1V0CR@1239|Firmicutes,24BIB@186801|Clostridia,261UA@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
XH1_k127_6233665_8	56780.SYN_00336	6.11e-17	81.0	COG0695@1|root,COG0695@2|Bacteria,1Q0AV@1224|Proteobacteria,43EMT@68525|delta/epsilon subdivisions,2X38N@28221|Deltaproteobacteria,2MSEP@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	-
XH1_k127_6233665_9	335543.Sfum_3598	6.121e-11	68.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2WRJR@28221|Deltaproteobacteria,2MS5B@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
XH1_k127_6233665_1	177437.HRM2_48280	1.705e-100	332.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MIJ0@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	PFAM Cytochrome C biogenesis protein transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
XH1_k127_6233665_5	1265505.ATUG01000001_gene4244	1.711e-35	139.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria,42UD9@68525|delta/epsilon subdivisions,2WQ0H@28221|Deltaproteobacteria,2MK3U@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	Thioredoxin	trx-2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
XH1_k127_6233665_4	335543.Sfum_3599	5.851e-42	159.0	COG4273@1|root,COG4273@2|Bacteria,1MZED@1224|Proteobacteria,42UH2@68525|delta/epsilon subdivisions,2WQNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DGC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DGC
XH1_k127_6233665_7	909663.KI867150_gene1420	1.012e-24	106.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2WRJR@28221|Deltaproteobacteria,2MS5U@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
XH1_k127_6233665_6	555079.Toce_1976	1.018e-25	107.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia,42EJS@68295|Thermoanaerobacterales	186801|Clostridia	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
XH1_k127_6310866_6	1328313.DS2_18518	0.0003048	54.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,YfiO
XH1_k127_6310866_0	439235.Dalk_0663	8.88e-105	355.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKG2@28221|Deltaproteobacteria,2MJ32@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	flbD	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_6310866_4	1174504.AJTN02000025_gene1724	4.006e-19	91.0	COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,4HIKW@91061|Bacilli,1ZHSN@1386|Bacillus	91061|Bacilli	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
XH1_k127_6310866_3	1167006.UWK_03071	8.629e-39	149.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,42TPI@68525|delta/epsilon subdivisions,2WP1C@28221|Deltaproteobacteria,2MJKP@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
XH1_k127_6310866_5	639282.DEFDS_0521	1.773e-13	74.0	COG1677@1|root,COG1677@2|Bacteria,2GFT6@200930|Deferribacteres	200930|Deferribacteres	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
XH1_k127_6310866_2	330214.NIDE2288	1.21e-82	295.0	COG1766@1|root,COG1766@2|Bacteria,3J0A6@40117|Nitrospirae	40117|Nitrospirae	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
XH1_k127_6310866_1	644282.Deba_0913	2.472e-92	314.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,42MS3@68525|delta/epsilon subdivisions,2WMCR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	flagellar motor switch protein FliG	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
XH1_k127_6334343_0	706587.Desti_4875	1.241e-58	211.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WNMC@28221|Deltaproteobacteria,2MQPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
XH1_k127_6334343_1	644282.Deba_0066	9.081e-43	178.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43EF4@68525|delta/epsilon subdivisions,2X87I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
XH1_k127_6343040_10	439235.Dalk_3336	5.46e-16	91.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42T11@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23,5.2.1.13	ko:K09516,ko:K09835	ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110	M00097	R07163,R07512	RC01835,RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
XH1_k127_6343040_6	880072.Desac_2776	1.12e-53	194.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2X5N8@28221|Deltaproteobacteria,2MS5W@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
XH1_k127_6343040_11	479434.Sthe_3458	5.479e-12	73.0	COG0717@1|root,COG0717@2|Bacteria,2G8PG@200795|Chloroflexi,27YDB@189775|Thermomicrobia	189775|Thermomicrobia	F	dUTPase	-	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
XH1_k127_6343040_9	1410665.JNKR01000001_gene328	6.271e-23	108.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,4H2TS@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
XH1_k127_6343040_7	56780.SYN_01006	1.332e-48	183.0	COG4123@1|root,COG4123@2|Bacteria,1MXEQ@1224|Proteobacteria,42SAA@68525|delta/epsilon subdivisions,2WPCM@28221|Deltaproteobacteria,2MQIQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Ribosomal protein L11 methyltransferase (PrmA)	-	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
XH1_k127_6343040_5	373903.Hore_14950	2.835e-62	231.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WB91@53433|Halanaerobiales	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
XH1_k127_6343040_3	648996.Theam_0136	8.246e-84	285.0	COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae	200783|Aquificae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
XH1_k127_6343040_1	1192034.CAP_8960	5.79e-191	604.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YUHC@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
XH1_k127_6343040_0	1125863.JAFN01000001_gene3464	1.85e-249	791.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
XH1_k127_6343040_8	887929.HMP0721_1155	5.342e-28	116.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,25WUG@186806|Eubacteriaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
XH1_k127_6343040_4	1125863.JAFN01000001_gene1376	7.486e-75	263.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Thiamine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
XH1_k127_6343040_12	56780.SYN_00040	2.077e-11	66.0	COG3242@1|root,COG3242@2|Bacteria,1NGPZ@1224|Proteobacteria,432RE@68525|delta/epsilon subdivisions,2WT10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
XH1_k127_6343040_2	648996.Theam_1729	1.843e-89	305.0	COG0809@1|root,COG0809@2|Bacteria,2G3KG@200783|Aquificae	200783|Aquificae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
XH1_k127_6361845_2	330214.NIDE0207	1.251e-34	136.0	2E01F@1|root,32VQP@2|Bacteria	2|Bacteria	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
XH1_k127_6361845_0	1265505.ATUG01000002_gene2333	6.981e-139	453.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,42N4S@68525|delta/epsilon subdivisions,2WJXX@28221|Deltaproteobacteria,2MIKA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
XH1_k127_6361845_1	1232437.KL661966_gene3132	2.101e-88	304.0	COG2230@1|root,COG3496@1|root,COG2230@2|Bacteria,COG3496@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WKGA@28221|Deltaproteobacteria,2MI5S@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS,DUF1365
XH1_k127_6397928_5	439235.Dalk_5014	2.926e-62	221.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2MJDX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
XH1_k127_6397928_10	1184267.A11Q_572	6.466e-35	147.0	COG1344@1|root,COG1344@2|Bacteria,1N1QF@1224|Proteobacteria,42TTV@68525|delta/epsilon subdivisions,2MT23@213481|Bdellovibrionales,2WQ6T@28221|Deltaproteobacteria	213481|Bdellovibrionales	N	Belongs to the bacterial flagellin family	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
XH1_k127_6397928_9	667014.Thein_0455	9.117e-36	141.0	COG1699@1|root,COG1699@2|Bacteria,2GIHJ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	FliW protein	-	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
XH1_k127_6397928_13	646529.Desaci_3786	5.46e-22	102.0	COG1763@1|root,COG1763@2|Bacteria,1V3U5@1239|Firmicutes,25CJD@186801|Clostridia,2676U@186807|Peptococcaceae	186801|Clostridia	H	Molybdopterin-guanine dinucleotide biosynthesis protein MobB	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
XH1_k127_6397928_4	926569.ANT_15460	9.748e-67	241.0	COG1092@1|root,COG1092@2|Bacteria,2G5YR@200795|Chloroflexi	200795|Chloroflexi	J	SMART PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
XH1_k127_6397928_8	1121346.KB899816_gene3353	6.088e-37	142.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,26Y4P@186822|Paenibacillaceae	91061|Bacilli	FG	HIT family	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
XH1_k127_6397928_3	289376.THEYE_A1955	3.313e-67	236.0	COG0106@1|root,COG0106@2|Bacteria,3J0KA@40117|Nitrospirae	40117|Nitrospirae	E	Histidine biosynthesis protein	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
XH1_k127_6397928_17	335543.Sfum_2604	2.324e-06	57.0	2DR6U@1|root,33AFB@2|Bacteria,1NGJY@1224|Proteobacteria,42X82@68525|delta/epsilon subdivisions,2WT92@28221|Deltaproteobacteria,2MSE1@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6397928_6	1121106.JQKB01000007_gene996	6.981e-55	199.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,2JPDI@204441|Rhodospirillales	204441|Rhodospirillales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
XH1_k127_6397928_0	644282.Deba_1140	3.725e-282	893.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
XH1_k127_6397928_16	1123386.AUIW01000006_gene1666	1.896e-10	66.0	COG2137@1|root,COG2137@2|Bacteria,1WJTS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
XH1_k127_6397928_1	404589.Anae109_3433	1.723e-147	476.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
XH1_k127_6397928_2	404589.Anae109_0456	6.969e-140	451.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2YTSX@29|Myxococcales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
XH1_k127_6397928_11	290397.Adeh_3960	8.052e-34	136.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2YVZ3@29|Myxococcales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
XH1_k127_6397928_7	269799.Gmet_0196	1.738e-54	208.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2WMDT@28221|Deltaproteobacteria,43TC5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Competence-damaged protein	cinA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
XH1_k127_6397928_14	1268239.PALB_1910	2.281e-14	73.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,2Q0U5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
XH1_k127_6397928_15	765910.MARPU_05055	3.319e-13	74.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1WY89@135613|Chromatiales	135613|Chromatiales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
XH1_k127_6397928_12	555079.Toce_1466	5.407e-22	100.0	COG2005@1|root,COG2005@2|Bacteria,1VFW6@1239|Firmicutes,25KE5@186801|Clostridia,42HCP@68295|Thermoanaerobacterales	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1
XH1_k127_6417814_7	269799.Gmet_1941	2.348e-24	108.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,43TKA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
XH1_k127_6417814_5	404380.Gbem_0617	1.658e-27	116.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,42TPK@68525|delta/epsilon subdivisions,2X6N1@28221|Deltaproteobacteria,43UXV@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
XH1_k127_6417814_2	1499967.BAYZ01000105_gene3533	1.951e-103	349.0	COG0303@1|root,COG0303@2|Bacteria,2NP4N@2323|unclassified Bacteria	2|Bacteria	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
XH1_k127_6417814_4	289377.HL41_04035	3.851e-33	145.0	COG1639@1|root,COG1639@2|Bacteria,2GGWZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
XH1_k127_6417814_3	1144275.COCOR_04000	1.968e-39	162.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1RAHZ@1224|Proteobacteria,42UGY@68525|delta/epsilon subdivisions,2WQPI@28221|Deltaproteobacteria,2YUG9@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
XH1_k127_6417814_0	398767.Glov_1025	8.613e-199	626.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,43T9E@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
XH1_k127_6417814_6	865861.AZSU01000002_gene2905	4.866e-25	105.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,36KES@31979|Clostridiaceae	186801|Clostridia	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
XH1_k127_6417814_1	667014.Thein_0552	7.571e-145	466.0	COG0216@1|root,COG0216@2|Bacteria,2GHCQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
XH1_k127_6417814_8	177437.HRM2_17090	3.346e-22	100.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2MHVH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
XH1_k127_6442845_3	1499967.BAYZ01000123_gene2554	4.434e-40	155.0	COG0309@1|root,COG0309@2|Bacteria	2|Bacteria	O	Hydrogenase expression formation protein (HypE)	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
XH1_k127_6442845_2	479434.Sthe_1344	2.189e-45	168.0	COG0309@1|root,COG0309@2|Bacteria,2G8E4@200795|Chloroflexi,27XEQ@189775|Thermomicrobia	189775|Thermomicrobia	O	AIR synthase related protein, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
XH1_k127_6442845_1	1123371.ATXH01000022_gene955	5.828e-98	326.0	COG1469@1|root,COG1469@2|Bacteria,2GGVY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
XH1_k127_6442845_4	1121918.ARWE01000001_gene1701	2.478e-36	142.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,42TJ5@68525|delta/epsilon subdivisions,2WQ2Z@28221|Deltaproteobacteria,43UWB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
XH1_k127_6442845_0	161156.JQKW01000007_gene814	6.991e-117	388.0	COG1702@1|root,COG1702@2|Bacteria,2GGQM@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
XH1_k127_6442845_5	1232410.KI421413_gene703	1.985e-26	119.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,42TCJ@68525|delta/epsilon subdivisions,2WPMW@28221|Deltaproteobacteria,43W0E@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Uncharacterized protein family UPF0054	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
XH1_k127_6442845_6	537972.ABQU01000030_gene424	6.868e-07	51.0	2A4CB@1|root,30SXZ@2|Bacteria,1PCGS@1224|Proteobacteria,42W82@68525|delta/epsilon subdivisions,2YQMV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6442845_7	32024.JMTI01000008_gene1227	0.0001461	47.0	2A4CB@1|root,30SXZ@2|Bacteria,1PCGS@1224|Proteobacteria,42W82@68525|delta/epsilon subdivisions,2YQMV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6450984_0	335543.Sfum_1550	0.0	1347.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MR5Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
XH1_k127_6450984_2	1307759.JOMJ01000003_gene406	6.598e-63	217.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2WND8@28221|Deltaproteobacteria,2MBJ6@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
XH1_k127_6450984_3	744872.Spica_0382	3.351e-55	199.0	COG0049@1|root,COG0049@2|Bacteria,2J7TX@203691|Spirochaetes	203691|Spirochaetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
XH1_k127_6450984_1	768670.Calni_1510	4.949e-302	942.0	COG0480@1|root,COG0480@2|Bacteria,2GFAG@200930|Deferribacteres	200930|Deferribacteres	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
XH1_k127_6450984_4	385682.AFSL01000100_gene30	1.788e-17	82.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,3XJ0R@558415|Marinilabiliaceae	976|Bacteroidetes	J	Elongation factor Tu C-terminal domain	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
XH1_k127_6468986_2	1232410.KI421428_gene1003	6.214e-85	292.0	COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,42RXX@68525|delta/epsilon subdivisions,2WNME@28221|Deltaproteobacteria,43TKF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
XH1_k127_6468986_4	909663.KI867150_gene1147	1.705e-68	245.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,42T3V@68525|delta/epsilon subdivisions,2X2EJ@28221|Deltaproteobacteria,2MSD1@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
XH1_k127_6468986_3	439235.Dalk_0385	1.805e-78	273.0	COG1148@1|root,COG1148@2|Bacteria,1R9EV@1224|Proteobacteria,42PIR@68525|delta/epsilon subdivisions,2WK4U@28221|Deltaproteobacteria	2|Bacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885,ko:K16886	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
XH1_k127_6468986_6	237368.SCABRO_02302	3.024e-54	207.0	COG2206@1|root,COG2206@2|Bacteria,2J3D3@203682|Planctomycetes	203682|Planctomycetes	T	signal transduction HD GYP protein	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
XH1_k127_6468986_1	316067.Geob_0389	1.82e-101	344.0	COG2974@1|root,COG2974@2|Bacteria,1N4GC@1224|Proteobacteria,42RPT@68525|delta/epsilon subdivisions,2WIWU@28221|Deltaproteobacteria,43S9R@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Putative exonuclease, RdgC	-	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
XH1_k127_6468986_8	269799.Gmet_2200	9.551e-42	166.0	COG0491@1|root,COG0491@2|Bacteria,1RB5G@1224|Proteobacteria,42QQ5@68525|delta/epsilon subdivisions,2WN4G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
XH1_k127_6468986_7	1173028.ANKO01000099_gene1557	1.959e-43	166.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,1HFHP@1150|Oscillatoriales	1117|Cyanobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
XH1_k127_6468986_5	880073.Calab_0491	6.396e-57	203.0	COG1881@1|root,COG1881@2|Bacteria,2NPDK@2323|unclassified Bacteria	2|Bacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
XH1_k127_6468986_0	335543.Sfum_1696	1.185e-112	371.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria,2MQSH@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
XH1_k127_651038_6	1121451.DESAM_10074	5.09e-19	88.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2M7X1@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
XH1_k127_651038_4	1121396.KB893084_gene403	1.319e-104	346.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42MSC@68525|delta/epsilon subdivisions,2WKIK@28221|Deltaproteobacteria,2MN31@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
XH1_k127_651038_5	1211035.CD30_10005	5.792e-73	267.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,3IWJK@400634|Lysinibacillus	91061|Bacilli	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
XH1_k127_651038_2	596151.DesfrDRAFT_2495	4.546e-138	446.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria,2MA30@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
XH1_k127_651038_3	596151.DesfrDRAFT_2496	1.53e-124	405.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2M8YK@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
XH1_k127_651038_1	941449.dsx2_1486	1.476e-161	518.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria,2M994@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
XH1_k127_651038_0	1121403.AUCV01000041_gene175	7.693e-172	548.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MI80@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class-III	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
XH1_k127_6532875_3	177437.HRM2_43040	4.428e-41	154.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,2MJS3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
XH1_k127_6532875_0	177437.HRM2_43030	2.262e-195	616.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria,2MJN6@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
XH1_k127_6532875_1	644282.Deba_0120	1.737e-88	298.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,42SY9@68525|delta/epsilon subdivisions,2X5HT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
XH1_k127_6532875_2	177437.HRM2_43020	1.713e-84	295.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,2MJTU@213118|Desulfobacterales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
XH1_k127_6535146_8	502025.Hoch_5623	7.961e-15	89.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1R8QH@1224|Proteobacteria,42T02@68525|delta/epsilon subdivisions,2WPNU@28221|Deltaproteobacteria,2YUP3@29|Myxococcales	28221|Deltaproteobacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
XH1_k127_6535146_4	1041930.Mtc_1463	3.186e-35	138.0	COG2050@1|root,arCOG00777@2157|Archaea,2XXGC@28890|Euryarchaeota,2N9TQ@224756|Methanomicrobia	224756|Methanomicrobia	Q	Thioesterase superfamily	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
XH1_k127_6535146_1	368407.Memar_1911	4.394e-62	222.0	COG1526@1|root,arCOG04358@2157|Archaea,2XY65@28890|Euryarchaeota,2NBJ5@224756|Methanomicrobia	224756|Methanomicrobia	C	TIGRFAM formate dehydrogenase family accessory protein FdhD	-	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
XH1_k127_6535146_3	443144.GM21_1336	1.803e-46	183.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2WNND@28221|Deltaproteobacteria,43T13@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
XH1_k127_6535146_0	439235.Dalk_1133	4.248e-79	275.0	COG0778@1|root,COG0778@2|Bacteria,1NJRA@1224|Proteobacteria,42XTT@68525|delta/epsilon subdivisions,2WSXH@28221|Deltaproteobacteria,2MMQ2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	TM1586_NiRdase
XH1_k127_6535146_2	1121405.dsmv_2823	1.964e-53	196.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2MK2V@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
XH1_k127_6535146_5	1340493.JNIF01000003_gene4206	9.731e-30	128.0	COG1496@1|root,COG1496@2|Bacteria	2|Bacteria	S	copper ion binding	yfiH	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
XH1_k127_6535146_7	521460.Athe_2763	4.206e-15	75.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
XH1_k127_6535146_9	1254432.SCE1572_15090	1.065e-11	71.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria,2YVYX@29|Myxococcales	28221|Deltaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
XH1_k127_6535146_6	1191523.MROS_1140	3.197e-22	97.0	COG0759@1|root,COG0759@2|Bacteria	2|Bacteria	M	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
XH1_k127_6535146_10	880072.Desac_0850	0.0006907	48.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2MQBM@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
XH1_k127_659645_0	1110502.TMO_2271	7.896e-125	417.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2TU9F@28211|Alphaproteobacteria,2JUW8@204441|Rhodospirillales	204441|Rhodospirillales	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
XH1_k127_659645_2	314292.VAS14_15709	2.545e-10	68.0	COG2755@1|root,COG2755@2|Bacteria,1NST7@1224|Proteobacteria,1SMK1@1236|Gammaproteobacteria,1Y0R4@135623|Vibrionales	135623|Vibrionales	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6602412_1	243231.GSU0775	3.221e-60	223.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
XH1_k127_6602412_4	237368.SCABRO_02485	2.156e-26	113.0	COG0745@1|root,COG0745@2|Bacteria	237368.SCABRO_02485|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6602412_2	635013.TherJR_0671	1.687e-54	208.0	COG0479@1|root,COG0479@2|Bacteria,1TP8R@1239|Firmicutes,247QI@186801|Clostridia	186801|Clostridia	C	Sulfite reductase, subunit A	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
XH1_k127_6602412_0	635013.TherJR_0670	1.007e-206	655.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,267CA@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
XH1_k127_6602412_3	335543.Sfum_1796	1.663e-48	180.0	COG3383@1|root,COG3383@2|Bacteria,1NW4J@1224|Proteobacteria,42RH9@68525|delta/epsilon subdivisions,2WNSH@28221|Deltaproteobacteria,2MSIH@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM molybdopterin oxidoreductase Fe4S4 region	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin
XH1_k127_6602412_5	1121866.AUGK01000011_gene541	1.33e-25	106.0	COG0543@1|root,COG0543@2|Bacteria,2HXFY@201174|Actinobacteria,4CV8F@84998|Coriobacteriia	84998|Coriobacteriia	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
XH1_k127_6619675_3	1122132.AQYH01000008_gene2739	1.823e-08	63.0	COG0613@1|root,COG0613@2|Bacteria,1PBDI@1224|Proteobacteria,2U1HY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PHP family	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6619675_1	439235.Dalk_3345	2.056e-84	294.0	COG0183@1|root,COG0183@2|Bacteria,1RGC4@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_N
XH1_k127_6619675_0	439235.Dalk_3344	2.108e-87	305.0	COG0183@1|root,COG0183@2|Bacteria,1MY04@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_N
XH1_k127_6619675_2	157783.LK03_19300	2.432e-11	68.0	COG3255@1|root,COG3255@2|Bacteria,1N206@1224|Proteobacteria,1S8RI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
XH1_k127_6643056_3	1125863.JAFN01000001_gene2657	1.607e-31	129.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,43BH1@68525|delta/epsilon subdivisions,2X6VI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
XH1_k127_6643056_5	1158318.ATXC01000001_gene1399	2.058e-12	74.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
XH1_k127_6643056_4	706587.Desti_1647	4.197e-28	117.0	COG0745@1|root,COG0745@2|Bacteria,1N3R6@1224|Proteobacteria,42TU3@68525|delta/epsilon subdivisions,2WQ9W@28221|Deltaproteobacteria,2MSJP@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
XH1_k127_6643056_0	314230.DSM3645_11616	3.889e-144	467.0	COG0448@1|root,COG0448@2|Bacteria,2IXP5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
XH1_k127_6643056_1	243231.GSU3205	2.055e-106	359.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,43TZ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
XH1_k127_6643056_2	667014.Thein_1279	1.855e-79	275.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,2GGVM@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
XH1_k127_6653201_1	305900.GV64_22300	1.741e-112	378.0	28MN9@1|root,2ZAXV@2|Bacteria,1PPEY@1224|Proteobacteria,1RYAD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6653201_0	243231.GSU1723	4.341e-131	439.0	COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,42MXP@68525|delta/epsilon subdivisions,2WMI1@28221|Deltaproteobacteria,43S3A@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
XH1_k127_6653201_2	85643.Tmz1t_1473	6.392e-112	384.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
XH1_k127_6658530_6	443143.GM18_2300	8.021e-55	204.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,42RID@68525|delta/epsilon subdivisions,2WN9N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase U62 modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
XH1_k127_6658530_7	289376.THEYE_A1043	2.245e-46	172.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argH	GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K00619,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0946	ASL_C2,Acetyltransf_1,Lyase_1
XH1_k127_6658530_2	243231.GSU2064	2.152e-78	286.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
XH1_k127_6658530_3	243231.GSU2065	1.162e-70	250.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,43SZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
XH1_k127_6658530_4	316067.Geob_2786	2.437e-66	243.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,43U10@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
XH1_k127_6658530_5	1125863.JAFN01000001_gene682	3.296e-61	222.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RMJ@68525|delta/epsilon subdivisions,2WNP9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
XH1_k127_6658530_8	1144275.COCOR_03223	1.146e-37	151.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2YZ27@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
XH1_k127_6658530_1	203119.Cthe_2256	2.196e-124	414.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WH8B@541000|Ruminococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
XH1_k127_6658530_9	1313265.JNIE01000002_gene637	1.745e-35	139.0	COG0359@1|root,COG0359@2|Bacteria,2G44E@200783|Aquificae	200783|Aquificae	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
XH1_k127_6658530_12	1232437.KL662033_gene2676	6.942e-20	100.0	COG4241@1|root,COG4241@2|Bacteria,1N4XJ@1224|Proteobacteria,42QCS@68525|delta/epsilon subdivisions,2WKDT@28221|Deltaproteobacteria,2MIFQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
XH1_k127_6658530_11	221027.JO40_10800	9.092e-25	105.0	COG0238@1|root,COG0238@2|Bacteria,2J8ZY@203691|Spirochaetes	203691|Spirochaetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
XH1_k127_6658530_14	118005.AWNK01000001_gene2037	1.447e-16	85.0	COG0360@1|root,COG0360@2|Bacteria	2|Bacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
XH1_k127_6658530_10	1123371.ATXH01000003_gene1973	3.917e-25	107.0	COG1254@1|root,COG1254@2|Bacteria,2GHZK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
XH1_k127_6658530_0	420246.GTNG_0256	2.097e-191	618.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,1WEJD@129337|Geobacillus	91061|Bacilli	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
XH1_k127_6658530_13	1232410.KI421414_gene2903	2.27e-17	85.0	COG1923@1|root,COG1923@2|Bacteria,1QSI0@1224|Proteobacteria,42UHR@68525|delta/epsilon subdivisions,2WQKN@28221|Deltaproteobacteria,43SP3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Hfq protein	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
XH1_k127_6752796_2	439235.Dalk_4894	8.776e-42	156.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,2MJS3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
XH1_k127_6752796_0	439235.Dalk_4895	8.382e-139	455.0	COG1775@1|root,COG1775@2|Bacteria,1NT47@1224|Proteobacteria,42Z5X@68525|delta/epsilon subdivisions,2WTU0@28221|Deltaproteobacteria,2MMMH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
XH1_k127_6752796_1	439235.Dalk_4897	3.492e-94	317.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42S61@68525|delta/epsilon subdivisions,2X5SR@28221|Deltaproteobacteria,2MPFW@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
XH1_k127_6752796_3	439235.Dalk_4898	2.48e-38	152.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42Z1Q@68525|delta/epsilon subdivisions,2WUFF@28221|Deltaproteobacteria,2MMV9@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
XH1_k127_6762818_5	1232447.BAHW02000027_gene2155	1.506e-34	140.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,26955@186813|unclassified Clostridiales	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
XH1_k127_6762818_4	338966.Ppro_2969	5.112e-40	156.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,42RJ4@68525|delta/epsilon subdivisions,2WNQ3@28221|Deltaproteobacteria,43SZQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
XH1_k127_6762818_1	1089548.KI783301_gene3323	2.992e-88	302.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,3WEPC@539002|Bacillales incertae sedis	91061|Bacilli	S	Large family of predicted nucleotide-binding domains	yacL	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TRAM
XH1_k127_6762818_3	335543.Sfum_3655	5.028e-49	180.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria,2MQG0@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
XH1_k127_6762818_0	269799.Gmet_1227	3.463e-94	316.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WMSH@28221|Deltaproteobacteria,43U4F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
XH1_k127_6762818_2	715451.ambt_03090	1.729e-56	208.0	COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,464UY@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Adenylate cyclase	cyaA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K05851	ko00230,ko02026,ko05111,map00230,map02026,map05111	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2672,iECOK1_1307.ECOK1_4253,iECS88_1305.ECS88_4229,iUMN146_1321.UM146_19155,iUTI89_1310.UTI89_C4365	Adenyl_cycl_N,Adenylate_cycl
XH1_k127_6788696_0	335543.Sfum_0420	5.369e-44	169.0	COG0664@1|root,COG0664@2|Bacteria,1QZ42@1224|Proteobacteria,42XK7@68525|delta/epsilon subdivisions,2WSIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
XH1_k127_6788696_1	1408452.JAGZ01000018_gene473	5.994e-40	162.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,2337P@1762|Mycobacteriaceae	201174|Actinobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
XH1_k127_6793246_1	56780.SYN_03230	2.562e-73	256.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2WKJ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
XH1_k127_6793246_6	593750.Metfor_0652	2.031e-18	91.0	COG1633@1|root,arCOG01102@2157|Archaea,2Y446@28890|Euryarchaeota,2NB0Q@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_6793246_3	1313265.JNIE01000004_gene610	4.127e-60	234.0	COG0761@1|root,COG0761@2|Bacteria,2G3IF@200783|Aquificae	200783|Aquificae	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
XH1_k127_6793246_2	903818.KI912268_gene895	1.172e-72	256.0	COG1189@1|root,COG1189@2|Bacteria,3Y3HM@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
XH1_k127_6793246_0	909663.KI867150_gene1238	1.48e-187	608.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,2MQAA@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
XH1_k127_6793246_4	1123242.JH636436_gene112	2.665e-59	216.0	COG0142@1|root,COG0142@2|Bacteria,2IX56@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
XH1_k127_6793246_5	1322246.BN4_10099	3.63e-42	166.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,42MX3@68525|delta/epsilon subdivisions,2WKI4@28221|Deltaproteobacteria,2MA90@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
XH1_k127_6808418_0	439235.Dalk_0366	2.177e-210	671.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
XH1_k127_6815775_10	335543.Sfum_3364	3.62e-18	84.0	COG2223@1|root,COG2223@2|Bacteria,1MVFQ@1224|Proteobacteria,43CFE@68525|delta/epsilon subdivisions,2X7QH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
XH1_k127_6815775_0	1125863.JAFN01000001_gene1819	2.422e-316	978.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WJY2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
XH1_k127_6815775_7	626939.HMPREF9443_00792	4.991e-46	177.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H21J@909932|Negativicutes	909932|Negativicutes	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA	-	-	ko:K16786	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
XH1_k127_6815775_8	443143.GM18_0860	1.712e-35	141.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,43V08@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
XH1_k127_6815775_1	706587.Desti_5288	5.489e-112	371.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,2MR47@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
XH1_k127_6815775_3	443144.GM21_3302	9.277e-78	267.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
XH1_k127_6815775_5	56780.SYN_01599	2.979e-50	186.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2WPH1@28221|Deltaproteobacteria,2MQGH@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
XH1_k127_6815775_6	338966.Ppro_0703	3.427e-47	172.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,42RE3@68525|delta/epsilon subdivisions,2WPD5@28221|Deltaproteobacteria,43UVG@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
XH1_k127_6815775_11	161156.JQKW01000006_gene1057	7.18e-13	69.0	COG0257@1|root,COG0257@2|Bacteria,2GI5G@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
XH1_k127_6815775_9	1291743.LOSG293_180060	4.484e-31	123.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,3F7CW@33958|Lactobacillaceae	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
XH1_k127_6815775_2	1125863.JAFN01000001_gene3315	2.217e-87	294.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2WJH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
XH1_k127_6815775_4	706587.Desti_5282	1.431e-64	224.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2MQSV@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
XH1_k127_681894_1	56780.SYN_01486	9.673e-70	241.0	COG0791@1|root,COG3087@1|root,COG0791@2|Bacteria,COG3087@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2WRIP@28221|Deltaproteobacteria,2MSJ0@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SPOR
XH1_k127_681894_0	767817.Desgi_4160	6.311e-215	675.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,260A2@186807|Peptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
XH1_k127_681894_2	247490.KSU1_C1021	3.564e-21	94.0	COG0355@1|root,COG0355@2|Bacteria,2J073@203682|Planctomycetes	203682|Planctomycetes	C	ATP synthase, Delta/Epsilon chain, beta-sandwich domain	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
XH1_k127_6826152_0	1382304.JNIL01000001_gene3291	6.547e-232	724.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,27812@186823|Alicyclobacillaceae	91061|Bacilli	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
XH1_k127_6826152_2	945713.IALB_0506	3.373e-46	175.0	COG2109@1|root,COG2109@2|Bacteria	2|Bacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
XH1_k127_6826152_1	96561.Dole_2160	1.177e-157	501.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42PRI@68525|delta/epsilon subdivisions,2X5GA@28221|Deltaproteobacteria,2MHVA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
XH1_k127_6828935_1	207559.Dde_0196	2.898e-148	481.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2M851@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
XH1_k127_6828935_4	443144.GM21_3362	2.218e-33	151.0	COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42URI@68525|delta/epsilon subdivisions,2WQ69@28221|Deltaproteobacteria,43U4E@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971,DUF748
XH1_k127_6828935_0	667014.Thein_0206	1.936e-156	510.0	COG2262@1|root,COG2262@2|Bacteria,2GH9H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
XH1_k127_6828935_5	909663.KI867150_gene2493	3.689e-21	100.0	COG0250@1|root,COG0250@2|Bacteria,1Q2A0@1224|Proteobacteria,437WT@68525|delta/epsilon subdivisions,2X36G@28221|Deltaproteobacteria,2MSA8@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
XH1_k127_6828935_3	177437.HRM2_11500	3.17e-52	199.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2WNEI@28221|Deltaproteobacteria,2MJKY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Divergent polysaccharide deacetylase	yibQ	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
XH1_k127_6828935_2	269799.Gmet_1853	3.284e-123	407.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,43SVH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	tail specific protease	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
XH1_k127_6831270_2	706587.Desti_4334	6.727e-42	157.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
XH1_k127_6831270_0	706587.Desti_4334	1.309e-116	387.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
XH1_k127_6831270_1	706587.Desti_4333	1.055e-91	311.0	COG0559@1|root,COG0559@2|Bacteria,1MXGK@1224|Proteobacteria,42NUW@68525|delta/epsilon subdivisions,2WMC0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
XH1_k127_6883038_3	439235.Dalk_3698	1.756e-25	115.0	2CC24@1|root,32VJT@2|Bacteria,1N5Y6@1224|Proteobacteria,42UPP@68525|delta/epsilon subdivisions,2WQ6U@28221|Deltaproteobacteria,2MKRU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
XH1_k127_6883038_0	314230.DSM3645_17550	4.171e-281	881.0	COG0058@1|root,COG0058@2|Bacteria,2IY0J@203682|Planctomycetes	203682|Planctomycetes	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
XH1_k127_6883038_2	1232410.KI421421_gene3549	1.036e-49	184.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2WPHH@28221|Deltaproteobacteria,43SH2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Peptidyl-tRNA hydrolase	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
XH1_k127_6883038_1	1125863.JAFN01000001_gene1129	1.631e-79	278.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
XH1_k127_6893444_6	1232410.KI421426_gene1402	2.04e-33	139.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,42TAG@68525|delta/epsilon subdivisions,2WPRH@28221|Deltaproteobacteria,43SJK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
XH1_k127_6893444_0	1121271.AUCM01000006_gene380	1.963e-178	573.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
XH1_k127_6893444_1	868864.Dester_0424	7.434e-148	479.0	COG0151@1|root,COG0151@2|Bacteria,2G3J3@200783|Aquificae	200783|Aquificae	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
XH1_k127_6893444_5	96561.Dole_1427	1.351e-51	190.0	COG0041@1|root,COG0151@1|root,COG0041@2|Bacteria,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MIPF@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
XH1_k127_6893444_7	404589.Anae109_1413	1.574e-28	122.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42UBZ@68525|delta/epsilon subdivisions,2WQ0E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the SUA5 family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
XH1_k127_6893444_3	596151.DesfrDRAFT_3521	2.386e-65	225.0	COG2033@1|root,COG2033@2|Bacteria,1RHE0@1224|Proteobacteria,42SB9@68525|delta/epsilon subdivisions,2WP2D@28221|Deltaproteobacteria,2MBEZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Desulfoferrodoxin ferrous iron-binding region	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
XH1_k127_6893444_4	706587.Desti_1245	1.175e-63	223.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,42S74@68525|delta/epsilon subdivisions,2WNFJ@28221|Deltaproteobacteria,2MRP3@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ferritin-like domain	ftn	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
XH1_k127_6893444_2	237368.SCABRO_02880	1.172e-124	407.0	COG0426@1|root,COG0426@2|Bacteria,2J28D@203682|Planctomycetes	203682|Planctomycetes	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
XH1_k127_6905848_6	1167006.UWK_01421	7.908e-13	73.0	COG5660@1|root,32WII@2|Bacteria,1R3ME@1224|Proteobacteria,43DKX@68525|delta/epsilon subdivisions,2X8S3@28221|Deltaproteobacteria,2MPQM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
XH1_k127_6905848_3	886293.Sinac_7174	1.978e-55	199.0	COG2716@1|root,COG2716@2|Bacteria	2|Bacteria	E	regulation of RNA biosynthetic process	gcvR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
XH1_k127_6905848_1	941824.TCEL_02022	7.856e-266	841.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
XH1_k127_6905848_0	56780.SYN_02049	6.374e-274	863.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2MQ5F@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
XH1_k127_6905848_4	443143.GM18_0002	1.417e-50	194.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,43T1D@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
XH1_k127_6905848_2	1121335.Clst_0009	6.861e-65	231.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3WHV1@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
XH1_k127_6905848_5	316067.Geob_0454	1.706e-23	101.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,43T9A@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
XH1_k127_6942637_0	439235.Dalk_1970	1.991e-100	340.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
XH1_k127_696773_5	338963.Pcar_1777	4.566e-09	59.0	COG2026@1|root,COG2026@2|Bacteria,1NP1I@1224|Proteobacteria,437H9@68525|delta/epsilon subdivisions,2WVKQ@28221|Deltaproteobacteria,43V3Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
XH1_k127_696773_1	1121935.AQXX01000135_gene3759	3.04e-147	482.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1XITC@135619|Oceanospirillales	135619|Oceanospirillales	G	Carbohydrate kinase	-	-	2.7.1.17,2.7.1.215	ko:K00854,ko:K00862	ko00040,ko01100,map00040,map01100	M00014	R01639,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
XH1_k127_696773_4	644968.DFW101_3710	2.587e-38	160.0	COG2006@1|root,COG2006@2|Bacteria,1N7GG@1224|Proteobacteria,42VMY@68525|delta/epsilon subdivisions,2WRZG@28221|Deltaproteobacteria,2M964@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
XH1_k127_696773_2	876044.IMCC3088_1490	5.952e-139	462.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
XH1_k127_696773_3	670292.JH26_23105	3.264e-87	296.0	COG0561@1|root,COG0561@2|Bacteria,1R4WX@1224|Proteobacteria,2TSDR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	hydrolases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
XH1_k127_696773_0	96561.Dole_2614	1.156e-172	549.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,42RXR@68525|delta/epsilon subdivisions,2WNHV@28221|Deltaproteobacteria,2MK34@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
XH1_k127_6998550_2	439235.Dalk_0154	9.55e-10	61.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NQ9@68525|delta/epsilon subdivisions,2WM2K@28221|Deltaproteobacteria,2MP9N@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.15,4.1.2.27	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	M00027,M00100	R00261,R00489,R01682,R02464,R02466,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
XH1_k127_6998550_0	1287116.X734_32505	1.801e-74	276.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	-	-	-	-	-	-	-	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
XH1_k127_6998550_1	1313421.JHBV01000035_gene2550	8.591e-47	175.0	COG1309@1|root,COG1309@2|Bacteria,4NMW9@976|Bacteroidetes,1ISMH@117747|Sphingobacteriia	976|Bacteroidetes	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_6998831_3	1499967.BAYZ01000084_gene3996	2.389e-36	146.0	COG1214@1|root,COG1214@2|Bacteria,2NPK8@2323|unclassified Bacteria	2|Bacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
XH1_k127_6998831_1	96561.Dole_0481	5.948e-96	336.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2MIEV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
XH1_k127_6998831_0	880072.Desac_2913	5.4e-105	352.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria,2MR0C@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
XH1_k127_6998831_4	642492.Clole_2422	7.153e-33	141.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia	186801|Clostridia	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
XH1_k127_6998831_2	123899.JPQP01000017_gene2391	3.983e-75	259.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,3T293@506|Alcaligenaceae	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
XH1_k127_6998831_6	411467.BACCAP_00246	8.397e-11	64.0	2DPV4@1|root,333HA@2|Bacteria,1VH7Z@1239|Firmicutes,24SC2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6998831_5	385682.AFSL01000100_gene30	6.205e-18	83.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,3XJ0R@558415|Marinilabiliaceae	976|Bacteroidetes	J	Elongation factor Tu C-terminal domain	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
XH1_k127_7000073_1	338963.Pcar_1720	1.349e-85	294.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,42Q7U@68525|delta/epsilon subdivisions,2WKEC@28221|Deltaproteobacteria,43U5T@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
XH1_k127_7000073_4	1232410.KI421422_gene1972	1.309e-17	85.0	COG1977@1|root,COG1977@2|Bacteria,1Q1PR@1224|Proteobacteria,43EY6@68525|delta/epsilon subdivisions,2XA1J@28221|Deltaproteobacteria,43VRU@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
XH1_k127_7000073_0	335543.Sfum_4079	6.236e-297	918.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42MZJ@68525|delta/epsilon subdivisions,2WJK1@28221|Deltaproteobacteria,2MQ7S@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
XH1_k127_7000073_2	933262.AXAM01000005_gene2469	6.894e-48	190.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WN9P@28221|Deltaproteobacteria,2MPHD@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
XH1_k127_7000073_3	1211114.ALIP01000050_gene1665	1.969e-27	115.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1X7FC@135614|Xanthomonadales	135614|Xanthomonadales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
XH1_k127_7000073_5	404589.Anae109_0948	2.296e-09	62.0	28S5K@1|root,2ZEH5@2|Bacteria,1NI42@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
XH1_k127_700966_5	526222.Desal_3161	2.41e-17	83.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42NP2@68525|delta/epsilon subdivisions,2WIY2@28221|Deltaproteobacteria,2M8N5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
XH1_k127_700966_6	316067.Geob_2341	0.0001233	46.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,42X2E@68525|delta/epsilon subdivisions,2WT3J@28221|Deltaproteobacteria,43VQD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SlyX	slyX	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
XH1_k127_700966_2	56780.SYN_00035	1.344e-90	306.0	COG2510@1|root,COG2510@2|Bacteria,1QV9N@1224|Proteobacteria,43BNU@68525|delta/epsilon subdivisions,2X704@28221|Deltaproteobacteria,2MRSY@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
XH1_k127_700966_4	573370.DMR_37990	2.66e-35	136.0	COG0296@1|root,COG0296@2|Bacteria,1N8WX@1224|Proteobacteria,42VNQ@68525|delta/epsilon subdivisions,2WQ7J@28221|Deltaproteobacteria,2MC6I@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase, family 13	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
XH1_k127_700966_0	864702.OsccyDRAFT_4498	3.177e-299	932.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,1H8QW@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
XH1_k127_700966_3	1125863.JAFN01000001_gene3462	1.487e-39	149.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
XH1_k127_700966_1	1499967.BAYZ01000171_gene5603	8.727e-180	569.0	COG0459@1|root,COG0459@2|Bacteria,2NNM6@2323|unclassified Bacteria	2|Bacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
XH1_k127_7012899_1	56780.SYN_00150	1.724e-85	292.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,43BH8@68525|delta/epsilon subdivisions,2X6VM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
XH1_k127_7012899_2	56780.SYN_00149	1.249e-59	224.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,42NBB@68525|delta/epsilon subdivisions,2WIMD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ResB family protein	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
XH1_k127_7012899_0	439235.Dalk_2773	8.288e-209	654.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria,2MNG5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
XH1_k127_7041731_8	880072.Desac_0599	1.148e-35	140.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2MQ6S@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
XH1_k127_7041731_4	555088.DealDRAFT_1347	7.14e-83	289.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,42JMA@68298|Syntrophomonadaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
XH1_k127_7041731_6	589865.DaAHT2_1481	4.078e-73	265.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2MHZT@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
XH1_k127_7041731_0	443144.GM21_0509	2.035e-170	546.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
XH1_k127_7041731_7	667014.Thein_0432	1.343e-46	181.0	COG0812@1|root,COG0812@2|Bacteria,2GHPE@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
XH1_k127_7041731_9	306537.jk0752	5.677e-09	66.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,22MQI@1653|Corynebacteriaceae	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
XH1_k127_7041731_1	1121918.ARWE01000001_gene878	2.467e-137	448.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
XH1_k127_7041731_2	1125863.JAFN01000001_gene3353	6.343e-122	402.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
XH1_k127_7041731_3	665571.STHERM_c05940	8.793e-90	308.0	COG0787@1|root,COG0787@2|Bacteria,2J5JY@203691|Spirochaetes	203691|Spirochaetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
XH1_k127_7041731_5	70601.3258225	8.151e-80	285.0	COG1042@1|root,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,243Q6@183968|Thermococci	183968|Thermococci	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2,Succ_CoA_lig
XH1_k127_7041731_10	443143.GM18_0409	0.0006993	48.0	COG1572@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.78	ko:K01218,ko:K13276	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH26	-	CARDB,CHB_HEX_C_1,F5_F8_type_C,Laminin_G_3
XH1_k127_705087_2	96561.Dole_1642	7.206e-65	227.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_705087_0	1121422.AUMW01000014_gene1315	3.282e-132	434.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,24FFI@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
XH1_k127_705087_1	83406.HDN1F_12620	6.534e-66	235.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Nitroreductase
XH1_k127_705087_4	1380358.JADJ01000039_gene1	1.448e-05	49.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1XJV3@135619|Oceanospirillales	135619|Oceanospirillales	Q	Non-ribosomal peptide synthetase modules and related protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
XH1_k127_7055583_5	639282.DEFDS_0215	3.702e-104	344.0	COG0329@1|root,COG0329@2|Bacteria,2GF1R@200930|Deferribacteres	200930|Deferribacteres	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
XH1_k127_7055583_1	1123371.ATXH01000005_gene2113	1.183e-158	510.0	COG0019@1|root,COG0019@2|Bacteria,2GHHY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
XH1_k127_7055583_2	648996.Theam_0146	9.451e-154	503.0	COG0165@1|root,COG0165@2|Bacteria,2G3PT@200783|Aquificae	200783|Aquificae	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
XH1_k127_7055583_0	56780.SYN_02157	3.665e-177	566.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2MQ5Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
XH1_k127_7055583_4	880072.Desac_2478	3.349e-104	351.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,2MQ5Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
XH1_k127_7055583_3	1121405.dsmv_0937	6.247e-122	403.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2MHRT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
XH1_k127_7055583_6	1125863.JAFN01000001_gene2582	5.938e-104	349.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
XH1_k127_7055583_8	1211114.ALIP01000050_gene1665	4.636e-27	112.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1X7FC@135614|Xanthomonadales	135614|Xanthomonadales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
XH1_k127_7057389_1	1121440.AUMA01000001_gene83	1.465e-61	214.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,2M90B@213115|Desulfovibrionales	28221|Deltaproteobacteria	BQ	PFAM histone deacetylase superfamily	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
XH1_k127_7057389_0	555079.Toce_0852	1.851e-136	453.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,24AJ7@186801|Clostridia,42F8T@68295|Thermoanaerobacterales	186801|Clostridia	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
XH1_k127_7057389_2	1476973.JMMB01000007_gene2890	0.0009117	51.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25SBR@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
XH1_k127_7059206_0	56780.SYN_03522	1.039e-308	955.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	TIGRFAM anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
XH1_k127_7059206_5	909663.KI867150_gene1671	7.994e-37	152.0	COG0784@1|root,COG4191@1|root,COG5002@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,42N46@68525|delta/epsilon subdivisions,2WJT4@28221|Deltaproteobacteria,2MQX0@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
XH1_k127_7059206_4	1259795.ARJK01000004_gene1362	5.71e-68	238.0	COG1180@1|root,COG1180@2|Bacteria,1UJJA@1239|Firmicutes,251M0@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
XH1_k127_7059206_3	1123508.JH636440_gene2646	5.077e-83	296.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
XH1_k127_7059206_2	517418.Ctha_2310	1.823e-84	307.0	COG0745@1|root,COG2202@1|root,COG3829@1|root,COG3852@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,COG5000@2|Bacteria,1FFR1@1090|Chlorobi	2|Bacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
XH1_k127_7059206_1	1089548.KI783301_gene129	1.746e-87	300.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,3WFB9@539002|Bacillales incertae sedis	91061|Bacilli	S	ATPase family associated with various cellular activities (AAA)	yeaC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
XH1_k127_7059206_7	1118235.CAJH01000044_gene2791	3.004e-11	74.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,1X33K@135614|Xanthomonadales	135614|Xanthomonadales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
XH1_k127_7059206_6	234267.Acid_0334	3.808e-26	125.0	COG1305@1|root,COG1305@2|Bacteria,3Y5BT@57723|Acidobacteria	57723|Acidobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
XH1_k127_7082600_7	439235.Dalk_1963	1.699e-13	79.0	COG2976@1|root,COG2976@2|Bacteria,1QVA2@1224|Proteobacteria,42S27@68525|delta/epsilon subdivisions,2X70J@28221|Deltaproteobacteria,2MPMA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21,TPR_6
XH1_k127_7082600_0	1232410.KI421416_gene2558	3.609e-103	359.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,43S8I@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
XH1_k127_7082600_5	243231.GSU2029	1.31e-15	83.0	COG3168@1|root,COG3168@2|Bacteria,1NMC2@1224|Proteobacteria,42WTR@68525|delta/epsilon subdivisions,2WSTB@28221|Deltaproteobacteria,43VGT@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilP	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
XH1_k127_7082600_3	177437.HRM2_11010	8.072e-33	136.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MJVB@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
XH1_k127_7082600_4	243231.GSU2031	1.261e-22	104.0	COG3166@1|root,COG3166@2|Bacteria,1Q1I0@1224|Proteobacteria,42W65@68525|delta/epsilon subdivisions,2WS79@28221|Deltaproteobacteria,43UXE@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Fimbrial assembly protein (PilN)	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
XH1_k127_7082600_1	1125863.JAFN01000001_gene2287	3.598e-101	340.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
XH1_k127_7082600_8	269799.Gmet_1432	7.6e-06	51.0	COG2919@1|root,COG2919@2|Bacteria,1NM5U@1224|Proteobacteria,42X2K@68525|delta/epsilon subdivisions,2WSPM@28221|Deltaproteobacteria,43VHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	divIC	-	-	ko:K05589,ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
XH1_k127_7082600_2	1121422.AUMW01000008_gene477	9.826e-43	165.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,261FX@186807|Peptococcaceae	186801|Clostridia	S	PFAM Rhomboid family protein	GlpG	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
XH1_k127_7082600_6	478741.JAFS01000001_gene1525	4.926e-14	74.0	COG3071@1|root,COG3071@2|Bacteria,46TBM@74201|Verrucomicrobia,37H13@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
XH1_k127_7116631_4	1123371.ATXH01000033_gene423	1.476e-05	48.0	COG1309@1|root,COG1309@2|Bacteria,2GHH2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_7116631_1	330214.NIDE3103	2.945e-72	269.0	COG1250@1|root,COG1250@2|Bacteria,3J1F9@40117|Nitrospirae	40117|Nitrospirae	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3	ko:K00074,ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH_N
XH1_k127_7116631_2	880073.Calab_0535	7.948e-59	228.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
XH1_k127_7116631_0	706587.Desti_4022	2.688e-81	278.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MQGX@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
XH1_k127_7116631_3	706587.Desti_4023	1.253e-38	151.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
XH1_k127_7116921_0	335543.Sfum_4058	5.885e-159	509.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,2MQYA@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
XH1_k127_7116921_5	338963.Pcar_0066	3.069e-50	190.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42URW@68525|delta/epsilon subdivisions,2WMYB@28221|Deltaproteobacteria,43SFS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
XH1_k127_7116921_3	1307436.PBF_11482	6.551e-78	270.0	COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,4HB6V@91061|Bacilli,1ZB50@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
XH1_k127_7116921_4	1303518.CCALI_01309	3.464e-60	222.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria	2|Bacteria	C	tartrate metabolic process	fumB	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
XH1_k127_7116921_2	1160707.AJIK01000007_gene1135	6.222e-82	282.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,4HA3C@91061|Bacilli,26DUU@186818|Planococcaceae	91061|Bacilli	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
XH1_k127_7116921_6	706587.Desti_5579	5.352e-31	129.0	COG0746@1|root,COG0746@2|Bacteria,1PJ8A@1224|Proteobacteria,43A1A@68525|delta/epsilon subdivisions,2X2C8@28221|Deltaproteobacteria,2MQMN@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
XH1_k127_7116921_1	926549.KI421517_gene2441	1.62e-122	410.0	COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
XH1_k127_7151841_3	1304284.L21TH_2563	5.605e-42	157.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,36E27@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,Fer4_10,POR_N,TPP_enzyme_C
XH1_k127_7151841_4	909663.KI867150_gene53	2.401e-32	131.0	COG0589@1|root,COG0589@2|Bacteria,1NNUM@1224|Proteobacteria,43A9J@68525|delta/epsilon subdivisions,2X2D7@28221|Deltaproteobacteria,2MSB9@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
XH1_k127_7151841_2	1131269.AQVV01000004_gene576	1.275e-66	238.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
XH1_k127_7151841_1	243231.GSU2550	1.854e-76	269.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,43U42@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
XH1_k127_7151841_0	667014.Thein_1586	4.314e-232	742.0	COG0550@1|root,COG0550@2|Bacteria,2GH60@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	Bacterial DNA topoisomeraes I ATP-binding domain	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
XH1_k127_7164361_8	1123400.KB904766_gene2954	3.13e-07	56.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,460XM@72273|Thiotrichales	72273|Thiotrichales	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
XH1_k127_7164361_4	269799.Gmet_2320	2.111e-71	253.0	COG1774@1|root,COG1774@2|Bacteria,1MZBX@1224|Proteobacteria,42NE3@68525|delta/epsilon subdivisions,2WK98@28221|Deltaproteobacteria,43TAA@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
XH1_k127_7164361_0	56780.SYN_00558	1.039e-240	760.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,2MQAG@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
XH1_k127_7164361_7	643562.Daes_1864	1.124e-13	77.0	2EN8Q@1|root,33FWH@2|Bacteria,1NJ9J@1224|Proteobacteria,42XE1@68525|delta/epsilon subdivisions,2WT2P@28221|Deltaproteobacteria,2MBRD@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7164361_3	589865.DaAHT2_0261	6.79e-75	265.0	COG1639@1|root,COG1639@2|Bacteria,1R8H3@1224|Proteobacteria,42PER@68525|delta/epsilon subdivisions,2X29A@28221|Deltaproteobacteria,2MNF5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
XH1_k127_7164361_5	1379281.AVAG01000017_gene992	2.418e-70	249.0	COG2199@1|root,COG3706@2|Bacteria,1QUKY@1224|Proteobacteria,42NYY@68525|delta/epsilon subdivisions,2WKIY@28221|Deltaproteobacteria,2M8WM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
XH1_k127_7164361_1	443143.GM18_1896	7.665e-185	587.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,43TS7@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
XH1_k127_7164361_6	478801.Ksed_05620	1.716e-41	160.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,1ZVTV@145357|Dermacoccaceae	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
XH1_k127_7164361_2	1232410.KI421418_gene2370	1.79e-84	291.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,43S66@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Glycoprotease family	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
XH1_k127_7200065_2	644282.Deba_0278	6.82e-39	156.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
XH1_k127_7200065_0	525897.Dbac_3356	1.071e-152	489.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2M7RW@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
XH1_k127_7200065_1	269799.Gmet_0103	1.726e-73	259.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria,43SUA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
XH1_k127_7200065_3	502025.Hoch_4792	4.47e-08	63.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YUPG@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
XH1_k127_7232132_2	316067.Geob_3303	3.548e-157	509.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43UHV@69541|Desulfuromonadales	28221|Deltaproteobacteria	JKL	helicase superfamily c-terminal domain	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
XH1_k127_7232132_3	589865.DaAHT2_0078	5.53e-148	472.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2MJ0G@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
XH1_k127_7232132_7	335283.Neut_2531	2.304e-50	188.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,2VRCS@28216|Betaproteobacteria,3737H@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF882)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
XH1_k127_7232132_5	290315.Clim_2069	3.096e-131	438.0	COG2989@1|root,COG2989@2|Bacteria,1FEJK@1090|Chlorobi	1090|Chlorobi	S	PFAM Peptidoglycan-binding domain 1 protein	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
XH1_k127_7232132_1	391589.RGAI101_493	2.559e-169	547.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2P1WR@2433|Roseobacter	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_7232132_4	269799.Gmet_1929	3.002e-140	454.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,42NHN@68525|delta/epsilon subdivisions,2WJ4S@28221|Deltaproteobacteria,43TP0@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
XH1_k127_7232132_0	243231.GSU1640	5.929e-200	631.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42MB8@68525|delta/epsilon subdivisions,2WIW7@28221|Deltaproteobacteria,43UFE@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome bd terminal oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
XH1_k127_7232132_6	56780.SYN_01949	3.482e-120	416.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria,2MQS6@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
XH1_k127_7240726_2	56780.SYN_00024	2.191e-87	291.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42QF5@68525|delta/epsilon subdivisions,2WK2K@28221|Deltaproteobacteria,2MQ3W@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_7240726_1	56780.SYN_00023	2.079e-152	499.0	COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,42PZC@68525|delta/epsilon subdivisions,2WK59@28221|Deltaproteobacteria,2MQUU@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
XH1_k127_7240726_0	338966.Ppro_1986	9.559e-162	517.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,42NT4@68525|delta/epsilon subdivisions,2WJFM@28221|Deltaproteobacteria,43T76@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
XH1_k127_7240726_3	439235.Dalk_0847	4.286e-37	141.0	COG2249@1|root,COG2249@2|Bacteria,1RB3G@1224|Proteobacteria,43ACI@68525|delta/epsilon subdivisions,2X5SE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
XH1_k127_7284060_2	56780.SYN_02616	2.297e-188	596.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2MRT2@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
XH1_k127_7284060_0	1121405.dsmv_2192	1.407e-265	832.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2WK62@28221|Deltaproteobacteria,2MI73@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
XH1_k127_7284060_1	439235.Dalk_1825	1.296e-242	760.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2MI51@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82,4.2.1.9	ko:K01687,ko:K22396	ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02429,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
XH1_k127_7284060_5	1121405.dsmv_1897	4.52e-47	172.0	COG1225@1|root,COG1225@2|Bacteria,1NN23@1224|Proteobacteria,42XJF@68525|delta/epsilon subdivisions,2WTAE@28221|Deltaproteobacteria,2MNXB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	AhpC/TSA antioxidant enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA_2
XH1_k127_7284060_3	1304885.AUEY01000078_gene1056	2.815e-130	423.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,42MXJ@68525|delta/epsilon subdivisions,2WKAC@28221|Deltaproteobacteria,2MJ1T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	acuI	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
XH1_k127_7284060_4	96561.Dole_2526	6.59e-92	321.0	COG1024@1|root,COG1024@2|Bacteria,1MW41@1224|Proteobacteria,42N51@68525|delta/epsilon subdivisions,2WKBV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_7284060_6	1304880.JAGB01000002_gene1616	3.237e-10	61.0	COG1410@1|root,COG1410@2|Bacteria,1V5ZS@1239|Firmicutes,24I4A@186801|Clostridia	186801|Clostridia	E	PFAM Vitamin B12 dependent methionine synthase, activation domain	-	-	-	-	-	-	-	-	-	-	-	-	Met_synt_B12
XH1_k127_7359216_1	56780.SYN_02105	1.206e-41	157.0	COG0224@1|root,COG0224@2|Bacteria,1N4GR@1224|Proteobacteria,42S5M@68525|delta/epsilon subdivisions,2WNX2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Gamma subunit	-	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
XH1_k127_7359216_0	1265505.ATUG01000003_gene568	5.183e-157	518.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MN09@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_8,PAS_9,Response_reg
XH1_k127_7359216_2	706587.Desti_2838	0.0001651	44.0	COG1149@1|root,COG1149@2|Bacteria,1R09H@1224|Proteobacteria,43CSK@68525|delta/epsilon subdivisions,2X808@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
XH1_k127_7362107_0	118163.Ple7327_3783	9.4e-323	1014.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,3VJEC@52604|Pleurocapsales	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
XH1_k127_7362107_1	706587.Desti_2695	7.008e-135	447.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	ribonuclease Rne Rng family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
XH1_k127_7362107_4	1121405.dsmv_1444	1.659e-53	194.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42QSV@68525|delta/epsilon subdivisions,2WMZ5@28221|Deltaproteobacteria,2MI25@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	yrdC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
XH1_k127_7362107_5	1125863.JAFN01000001_gene920	2.966e-49	185.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
XH1_k127_7362107_3	1125863.JAFN01000001_gene1885	4.578e-69	248.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
XH1_k127_7362107_2	1125863.JAFN01000001_gene1886	1.881e-120	408.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
XH1_k127_7362107_6	269798.CHU_1101	2.255e-33	132.0	COG5184@1|root,COG5184@2|Bacteria,4NIP4@976|Bacteroidetes,47T9H@768503|Cytophagia	976|Bacteroidetes	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,RCC1
XH1_k127_7367725_0	103690.17134355	3.955e-152	492.0	COG1253@1|root,COG1253@2|Bacteria,1G16U@1117|Cyanobacteria,1HISP@1161|Nostocales	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
XH1_k127_7367725_2	269796.Rru_A2605	5.455e-56	201.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,2U8QT@28211|Alphaproteobacteria,2JSGE@204441|Rhodospirillales	204441|Rhodospirillales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
XH1_k127_7367725_4	903818.KI912269_gene88	1.436e-08	65.0	COG0745@1|root,COG0745@2|Bacteria	903818.KI912269_gene88|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7367725_1	880073.Calab_3013	9.957e-69	246.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
XH1_k127_7367725_3	1125863.JAFN01000001_gene1612	2.14e-30	128.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5H@1224|Proteobacteria,42SFF@68525|delta/epsilon subdivisions,2WP85@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	metal-dependent phosphohydrolase HD	-	-	-	-	-	-	-	-	-	-	-	-	HD
XH1_k127_7369122_2	555088.DealDRAFT_0639	2.023e-162	517.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,42KCG@68298|Syntrophomonadaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73	ko:K00052,ko:K07246	ko00290,ko00630,ko00650,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00630,map00650,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00215,R00994,R01751,R02545,R04426,R06180,R10052	RC00084,RC00105,RC00417,RC00594,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
XH1_k127_7369122_5	1167006.UWK_02832	2.845e-114	381.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2WK3V@28221|Deltaproteobacteria,2MIQC@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
XH1_k127_7369122_9	931276.Cspa_c17860	4.638e-16	84.0	COG4892@1|root,COG4892@2|Bacteria,1VPPE@1239|Firmicutes,24KBV@186801|Clostridia,36K0D@31979|Clostridiaceae	186801|Clostridia	S	Cytochrome b5	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7369122_10	706587.Desti_0052	4.319e-13	74.0	2EFBZ@1|root,3394W@2|Bacteria,1NKS3@1224|Proteobacteria,42WXW@68525|delta/epsilon subdivisions,2WSUB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
XH1_k127_7369122_0	909663.KI867150_gene2531	9.467e-239	752.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2MQ8Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Thiamine pyrophosphate enzyme, central	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
XH1_k127_7369122_6	909663.KI867150_gene2532	7.934e-55	205.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2WNBY@28221|Deltaproteobacteria,2MQHD@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
XH1_k127_7369122_3	1125863.JAFN01000001_gene2480	2.965e-159	507.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
XH1_k127_7369122_8	522772.Dacet_0469	7.567e-50	184.0	COG0688@1|root,COG0688@2|Bacteria,2GFF8@200930|Deferribacteres	200930|Deferribacteres	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
XH1_k127_7369122_7	1322246.BN4_10111	1.569e-54	207.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,2M8CV@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
XH1_k127_7369122_1	56780.SYN_00090	2.112e-195	623.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2MQXU@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
XH1_k127_7369122_4	439235.Dalk_0181	1.712e-120	392.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2MHP1@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
XH1_k127_7375526_3	909663.KI867149_gene3173	6.629e-96	339.0	COG2197@1|root,COG2208@1|root,COG2197@2|Bacteria,COG2208@2|Bacteria,1R3YQ@1224|Proteobacteria,42N0Q@68525|delta/epsilon subdivisions,2WM6W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_4,PAS_9
XH1_k127_7375526_6	1415780.JPOG01000001_gene3218	7.748e-48	174.0	COG0727@1|root,COG0727@2|Bacteria,1N027@1224|Proteobacteria,1S949@1236|Gammaproteobacteria,1X7SA@135614|Xanthomonadales	135614|Xanthomonadales	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
XH1_k127_7375526_2	243231.GSU1303	3.504e-109	373.0	COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,HBM,MCPsignal
XH1_k127_7375526_9	644282.Deba_1223	1.079e-13	76.0	2ECCP@1|root,336AZ@2|Bacteria,1N9PN@1224|Proteobacteria,42W93@68525|delta/epsilon subdivisions,2WRXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
XH1_k127_7375526_1	1150626.PHAMO_10109	1.479e-133	439.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2TQJY@28211|Alphaproteobacteria,2JQ50@204441|Rhodospirillales	204441|Rhodospirillales	G	Domain of unknown function (DUF4147)	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
XH1_k127_7375526_8	56780.SYN_02142	9.359e-25	110.0	2EUFT@1|root,33MY2@2|Bacteria,1NMCP@1224|Proteobacteria,42XWX@68525|delta/epsilon subdivisions,2WTB3@28221|Deltaproteobacteria,2MQQ5@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7375526_5	56780.SYN_02143	1.838e-82	280.0	COG0491@1|root,COG0491@2|Bacteria,1RJQM@1224|Proteobacteria,42SK3@68525|delta/epsilon subdivisions,2WPR1@28221|Deltaproteobacteria,2MRSM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
XH1_k127_7375526_4	1167006.UWK_01188	2.459e-83	284.0	COG2316@1|root,COG2316@2|Bacteria,1RA50@1224|Proteobacteria,42QZZ@68525|delta/epsilon subdivisions,2WMUN@28221|Deltaproteobacteria,2MJHQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
XH1_k127_7375526_0	158190.SpiGrapes_2709	5.182e-168	537.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
XH1_k127_7375526_7	158190.SpiGrapes_2708	2.575e-36	141.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
XH1_k127_7375900_0	309799.DICTH_0897	5.241e-135	445.0	COG0439@1|root,COG0439@2|Bacteria	2|Bacteria	I	biotin carboxylase activity	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
XH1_k127_7375900_1	469381.Dpep_1702	5.97e-29	121.0	COG0477@1|root,COG2814@2|Bacteria,3TAXB@508458|Synergistetes	508458|Synergistetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
XH1_k127_7377075_0	177437.HRM2_34200	1.594e-83	281.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,43BKJ@68525|delta/epsilon subdivisions,2WIZJ@28221|Deltaproteobacteria,2MKQX@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH1_k127_7377075_1	177437.HRM2_18320	7.761e-35	142.0	COG0398@1|root,COG0398@2|Bacteria,1RDYV@1224|Proteobacteria,42X0Y@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
XH1_k127_7377075_3	522306.CAP2UW1_1842	6.902e-07	59.0	COG0500@1|root,COG2226@2|Bacteria,1Q73B@1224|Proteobacteria,2W6KU@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
XH1_k127_7377075_2	1304885.AUEY01000095_gene2623	4.149e-19	89.0	COG2010@1|root,COG2010@2|Bacteria,1NKKK@1224|Proteobacteria,42UAC@68525|delta/epsilon subdivisions,2WXVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
XH1_k127_73839_18	335543.Sfum_1034	3.642e-26	111.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,2MR88@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
XH1_k127_73839_19	702450.CUW_1759	7.481e-26	113.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,3VQB8@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
XH1_k127_73839_0	56780.SYN_01983	4.878e-295	917.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MR7D@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
XH1_k127_73839_21	335543.Sfum_2544	3.63e-06	55.0	COG2331@1|root,COG2331@2|Bacteria,1NA92@1224|Proteobacteria,42VCN@68525|delta/epsilon subdivisions,2WRQP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
XH1_k127_73839_7	485915.Dret_1082	1.606e-120	398.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2M8Q4@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
XH1_k127_73839_20	398767.Glov_2285	3.05e-15	77.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,42V07@68525|delta/epsilon subdivisions,2WRQ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
XH1_k127_73839_2	1125863.JAFN01000001_gene1530	3.799e-190	602.0	COG0191@1|root,COG0191@2|Bacteria,1NMAK@1224|Proteobacteria,42NPW@68525|delta/epsilon subdivisions,2WIMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Ketose-bisphosphate aldolase, class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
XH1_k127_73839_6	639282.DEFDS_1408	4.815e-127	418.0	COG0158@1|root,COG0158@2|Bacteria,2GFC0@200930|Deferribacteres	200930|Deferribacteres	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
XH1_k127_73839_8	760568.Desku_1857	1.578e-109	370.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,260ZU@186807|Peptococcaceae	186801|Clostridia	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
XH1_k127_73839_11	479434.Sthe_1877	5.252e-64	229.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi,27Y8S@189775|Thermomicrobia	189775|Thermomicrobia	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
XH1_k127_73839_10	562970.Btus_1721	6.804e-88	301.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,2781D@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
XH1_k127_73839_14	1286171.EAL2_808p03700	2.243e-46	177.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,25UVS@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
XH1_k127_73839_16	1121468.AUBR01000014_gene2227	1.02e-29	126.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,42GMF@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
XH1_k127_73839_4	861299.J421_3363	5.302e-157	507.0	COG0133@1|root,COG0133@2|Bacteria,1ZSUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
XH1_k127_73839_13	644282.Deba_0632	2.913e-49	196.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
XH1_k127_73839_15	1122604.JONR01000022_gene671	3.338e-32	134.0	2CD6U@1|root,32RX5@2|Bacteria,1N8DY@1224|Proteobacteria,1SF31@1236|Gammaproteobacteria,1X8KS@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_73839_12	96561.Dole_2175	2.596e-60	215.0	COG1309@1|root,COG1309@2|Bacteria,1Q570@1224|Proteobacteria,430PJ@68525|delta/epsilon subdivisions,2WVWD@28221|Deltaproteobacteria,2MNQD@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_73839_3	644282.Deba_0575	6.735e-186	586.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42QAU@68525|delta/epsilon subdivisions,2WMD2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	ko:K11731	ko00281,map00281	-	R08089	RC01893	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_73839_1	439235.Dalk_3171	9.175e-267	832.0	COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,42N3T@68525|delta/epsilon subdivisions,2WIVU@28221|Deltaproteobacteria,2MMTK@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Pfam:DUF1446	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
XH1_k127_73839_9	439235.Dalk_2073	3.083e-91	307.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,42RTA@68525|delta/epsilon subdivisions,2WNCA@28221|Deltaproteobacteria,2MMZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
XH1_k127_73839_17	96561.Dole_2178	8.803e-28	124.0	COG4770@1|root,COG4770@2|Bacteria,1NK07@1224|Proteobacteria,4375X@68525|delta/epsilon subdivisions,2WT0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
XH1_k127_73839_5	96561.Dole_2179	6.453e-134	432.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2MHYZ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Carbamoyl-phosphate synthase L chain	pccA	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
XH1_k127_747913_2	56780.SYN_02186	1.461e-116	389.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,2MQ6W@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
XH1_k127_747913_3	96561.Dole_2190	6.62e-57	205.0	COG1309@1|root,COG1309@2|Bacteria,1N6R3@1224|Proteobacteria,42N4M@68525|delta/epsilon subdivisions,2WQ5F@28221|Deltaproteobacteria,2MKF8@213118|Desulfobacterales	28221|Deltaproteobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
XH1_k127_747913_0	439235.Dalk_0828	0.0	1281.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,2MI4X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM formate C-acetyltransferase glycine radical	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
XH1_k127_747913_1	96561.Dole_2192	3.529e-126	411.0	COG1180@1|root,COG1180@2|Bacteria,1QJHU@1224|Proteobacteria,42R2E@68525|delta/epsilon subdivisions,2WMYN@28221|Deltaproteobacteria,2MJPF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
XH1_k127_7483129_1	335543.Sfum_1084	8.785e-65	228.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2MQ4F@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
XH1_k127_7483129_0	56780.SYN_00851	3.006e-172	553.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MRU@68525|delta/epsilon subdivisions,2WIQX@28221|Deltaproteobacteria,2MQAX@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
XH1_k127_7564822_3	1191523.MROS_0995	5.542e-51	187.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
XH1_k127_7564822_0	555088.DealDRAFT_0130	7.726e-102	338.0	COG1600@1|root,COG1600@2|Bacteria,1UFJF@1239|Firmicutes,24GR0@186801|Clostridia	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7564822_2	1232437.KL662015_gene1287	3.282e-53	192.0	COG1765@1|root,COG1765@2|Bacteria,1N1T3@1224|Proteobacteria,42UFR@68525|delta/epsilon subdivisions,2WQ83@28221|Deltaproteobacteria,2MMSD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
XH1_k127_7564822_1	224325.AF_0688	8.633e-82	284.0	COG1145@1|root,arCOG02189@2157|Archaea,2Y4FX@28890|Euryarchaeota	28890|Euryarchaeota	C	ferredoxin iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
XH1_k127_7597201_2	909663.KI867150_gene2231	6.476e-46	175.0	COG0454@1|root,COG0456@2|Bacteria,1R418@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
XH1_k127_7597201_0	344747.PM8797T_05550	9.486e-135	438.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IZS3@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18
XH1_k127_7597201_1	744872.Spica_0027	4.353e-94	316.0	COG0334@1|root,COG0334@2|Bacteria,2J5DD@203691|Spirochaetes	203691|Spirochaetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gluD	-	1.4.1.2,1.4.1.3	ko:K00260,ko:K00261	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
XH1_k127_7597718_3	104623.Ser39006_00534	9.971e-05	50.0	28VP7@1|root,2ZHR6@2|Bacteria,1P8M3@1224|Proteobacteria,1SVC4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7597718_4	367336.OM2255_11840	0.00011	53.0	COG1388@1|root,COG1388@2|Bacteria,1QZEZ@1224|Proteobacteria,2TY8C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Pfam:Invasin_beta	-	-	-	-	-	-	-	-	-	-	-	-	IAT_beta
XH1_k127_7597718_1	767817.Desgi_1994	5.733e-68	243.0	COG1085@1|root,COG1085@2|Bacteria,1V675@1239|Firmicutes,24JTF@186801|Clostridia,263QP@186807|Peptococcaceae	186801|Clostridia	C	galactose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7597718_0	706587.Desti_1747	1.287e-73	253.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MQC2@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
XH1_k127_7597718_2	713586.KB900536_gene2347	6.406e-10	59.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1WWF1@135613|Chromatiales	135613|Chromatiales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
XH1_k127_7614102_6	644282.Deba_1370	7.854e-60	213.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42M7J@68525|delta/epsilon subdivisions,2WK1N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
XH1_k127_7614102_3	177437.HRM2_45420	2.915e-136	439.0	COG1177@1|root,COG1177@2|Bacteria,1MWVC@1224|Proteobacteria,42PRM@68525|delta/epsilon subdivisions,2WM44@28221|Deltaproteobacteria,2MN3J@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
XH1_k127_7614102_2	177437.HRM2_45430	1.737e-138	445.0	COG1176@1|root,COG1176@2|Bacteria,1MW9Y@1224|Proteobacteria,42N6W@68525|delta/epsilon subdivisions,2WM70@28221|Deltaproteobacteria,2MN5U@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
XH1_k127_7614102_1	177437.HRM2_45440	1.136e-168	536.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NS4@68525|delta/epsilon subdivisions,2WJT9@28221|Deltaproteobacteria,2MMRH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TOBE domain	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
XH1_k127_7614102_0	177437.HRM2_45450	3.789e-177	561.0	COG0687@1|root,COG0687@2|Bacteria,1MU12@1224|Proteobacteria,42NHM@68525|delta/epsilon subdivisions,2WKES@28221|Deltaproteobacteria,2MMJT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
XH1_k127_7614102_4	670487.Ocepr_0424	2.506e-92	312.0	COG0518@1|root,COG0518@2|Bacteria	2|Bacteria	F	GMP synthase (glutamine-hydrolyzing) activity	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
XH1_k127_7614102_5	670487.Ocepr_0425	2.056e-87	296.0	COG0584@1|root,COG0584@2|Bacteria,1WKK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
XH1_k127_7614102_7	370438.PTH_0487	0.0002839	44.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,260VN@186807|Peptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
XH1_k127_7625565_7	1047013.AQSP01000114_gene692	4.536e-11	63.0	COG0384@1|root,COG0384@2|Bacteria,2NR2U@2323|unclassified Bacteria	2|Bacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
XH1_k127_7625565_0	1301098.PKB_1465	2.692e-267	847.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG2366 Protein related to penicillin acylase	quiP	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
XH1_k127_7625565_1	203119.Cthe_3196	2.806e-144	470.0	COG4198@1|root,COG4198@2|Bacteria,1TQ52@1239|Firmicutes,24985@186801|Clostridia,3WGM6@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
XH1_k127_7625565_6	945713.IALB_0952	2.366e-22	102.0	COG4704@1|root,COG4704@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
XH1_k127_7625565_2	1121918.ARWE01000001_gene2756	3.665e-101	341.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2WJC6@28221|Deltaproteobacteria,43T6F@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
XH1_k127_7625565_5	1163407.UU7_15670	5.478e-38	162.0	COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,1SDNN@1236|Gammaproteobacteria,1X44C@135614|Xanthomonadales	135614|Xanthomonadales	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
XH1_k127_7625565_3	626887.J057_17290	1.74e-95	320.0	COG0697@1|root,COG0697@2|Bacteria,1QSKQ@1224|Proteobacteria,1RYG1@1236|Gammaproteobacteria,466BE@72275|Alteromonadaceae	1236|Gammaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	EamA
XH1_k127_7625565_4	443144.GM21_3583	9.548e-39	147.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,43UVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM OmpA MotB domain protein	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
XH1_k127_7626595_6	1353528.DT23_17780	2.151e-32	136.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_7626595_4	96561.Dole_0184	1.684e-63	230.0	COG1309@1|root,COG1309@2|Bacteria,1Q299@1224|Proteobacteria,42UP4@68525|delta/epsilon subdivisions,2WQF0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_7626595_3	439235.Dalk_4363	4.862e-86	300.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
XH1_k127_7626595_2	439235.Dalk_4898	1.327e-92	311.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42Z1Q@68525|delta/epsilon subdivisions,2WUFF@28221|Deltaproteobacteria,2MMV9@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
XH1_k127_7626595_1	439235.Dalk_4897	1.201e-94	317.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42S61@68525|delta/epsilon subdivisions,2X5SR@28221|Deltaproteobacteria,2MPFW@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
XH1_k127_7626595_0	96561.Dole_2770	3.754e-145	476.0	COG1775@1|root,COG1775@2|Bacteria,1NT47@1224|Proteobacteria,42Z5X@68525|delta/epsilon subdivisions,2WTU0@28221|Deltaproteobacteria,2MMMH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
XH1_k127_7626595_5	439235.Dalk_4894	1.545e-50	182.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,2MJS3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
XH1_k127_767140_2	1408321.JNJD01000006_gene1315	2.877e-12	68.0	COG0031@1|root,COG0031@2|Bacteria,1UZYC@1239|Firmicutes,24BVR@186801|Clostridia,27TFM@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
XH1_k127_767140_1	1379698.RBG1_1C00001G1206	8.043e-90	310.0	COG1215@1|root,COG1215@2|Bacteria,2NQN7@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
XH1_k127_767140_0	1265505.ATUG01000001_gene2927	9.805e-188	606.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MHYV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase N terminal	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
XH1_k127_767533_5	402777.KB235904_gene4531	1.006e-09	71.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
XH1_k127_767533_1	1121405.dsmv_2334	1.443e-60	216.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,42RQP@68525|delta/epsilon subdivisions,2WNQ7@28221|Deltaproteobacteria,2MK7M@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Calcineurin-like phosphoesterase	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos,Metallophos_2
XH1_k127_767533_4	1232410.KI421415_gene3098	1.118e-28	124.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,43SEE@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
XH1_k127_767533_0	247490.KSU1_D0598	1.48e-63	229.0	COG2199@1|root,COG3706@2|Bacteria,2J108@203682|Planctomycetes	203682|Planctomycetes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
XH1_k127_767533_3	522306.CAP2UW1_3042	6.937e-29	126.0	COG1639@1|root,COG2114@1|root,COG1639@2|Bacteria,COG2114@2|Bacteria,1RASR@1224|Proteobacteria,2VR0D@28216|Betaproteobacteria	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
XH1_k127_767533_2	316274.Haur_4259	1.631e-51	203.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
XH1_k127_7676672_2	439235.Dalk_2742	8.707e-64	229.0	COG0571@1|root,COG0613@1|root,COG0571@2|Bacteria,COG0613@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2X73H@28221|Deltaproteobacteria,2MII1@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3,3.1.3.97	ko:K03685,ko:K07053	ko03008,ko05205,map03008,map05205	-	R00188,R11188	RC00078	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	PHP,Ribonucleas_3_3,dsrm
XH1_k127_7676672_3	644282.Deba_1057	1.009e-45	168.0	COG0745@1|root,COG0745@2|Bacteria,1N3R6@1224|Proteobacteria,42TU3@68525|delta/epsilon subdivisions,2WQ9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
XH1_k127_7676672_1	644282.Deba_1058	3.113e-150	485.0	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
XH1_k127_7676672_0	264732.Moth_1918	1.487e-188	604.0	COG1061@1|root,COG1061@2|Bacteria,1TPDM@1239|Firmicutes,24CK8@186801|Clostridia	186801|Clostridia	KL	Helicase conserved C-terminal domain	-	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
XH1_k127_7676672_6	1120973.AQXL01000134_gene1557	2.988e-10	73.0	2ACIQ@1|root,3124W@2|Bacteria,1V104@1239|Firmicutes,4HFYB@91061|Bacilli,277Z3@186823|Alicyclobacillaceae	91061|Bacilli	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
XH1_k127_7676672_4	1304885.AUEY01000055_gene196	1.047e-33	146.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,2MHRK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48,TPR_14,TPR_16,TPR_19
XH1_k127_7676672_5	330214.NIDE3397	1.085e-14	81.0	COG1470@1|root,COG4733@1|root,COG1470@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	CHRD,DUF11,F5_F8_type_C,FG-GAP_2,NPCBM_assoc,SLH,VCBS,fn3
XH1_k127_7706188_6	1232437.KL661988_gene254	1.801e-29	120.0	COG1396@1|root,COG3837@1|root,COG1396@2|Bacteria,COG3837@2|Bacteria,1RCYA@1224|Proteobacteria,42QGN@68525|delta/epsilon subdivisions,2WIZH@28221|Deltaproteobacteria,2MJC3@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
XH1_k127_7706188_1	1121405.dsmv_0424	5.971e-131	428.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MI0N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_7706188_0	639282.DEFDS_0007	8.294e-169	550.0	COG0445@1|root,COG0445@2|Bacteria,2GF5H@200930|Deferribacteres	200930|Deferribacteres	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
XH1_k127_7706188_4	96561.Dole_0027	4.302e-40	160.0	COG3637@1|root,COG3637@2|Bacteria,1Q0E4@1224|Proteobacteria,42S0F@68525|delta/epsilon subdivisions,2WNUF@28221|Deltaproteobacteria,2MKN0@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7706188_2	667014.Thein_1135	1.37e-63	225.0	COG2231@1|root,COG2231@2|Bacteria,2GH00@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	endonuclease III	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
XH1_k127_7706188_5	1408287.AXUR01000010_gene1786	3.487e-33	138.0	COG1024@1|root,COG1024@2|Bacteria,3795J@32066|Fusobacteria	32066|Fusobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
XH1_k127_7706188_3	59374.Fisuc_2334	5.744e-49	194.0	COG1570@1|root,COG1570@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
XH1_k127_771117_2	1499967.BAYZ01000076_gene842	1.489e-48	195.0	COG0457@1|root,COG0457@2|Bacteria,2NQJ6@2323|unclassified Bacteria	2|Bacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
XH1_k127_771117_0	589865.DaAHT2_0099	1.682e-132	434.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MXG@68525|delta/epsilon subdivisions,2WJ6G@28221|Deltaproteobacteria,2MJ69@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
XH1_k127_771117_1	502025.Hoch_5071	9.115e-54	192.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
XH1_k127_7753249_2	56780.SYN_01166	3.078e-80	271.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MR3T@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
XH1_k127_7753249_0	96561.Dole_0769	4.196e-179	571.0	COG0277@1|root,COG0277@2|Bacteria,1MY08@1224|Proteobacteria,42Q28@68525|delta/epsilon subdivisions,2X5UF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
XH1_k127_7753249_1	96561.Dole_0770	1.432e-128	424.0	COG0247@1|root,COG0247@2|Bacteria,1R8K1@1224|Proteobacteria,42MRC@68525|delta/epsilon subdivisions,2WMEA@28221|Deltaproteobacteria,2MN2E@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
XH1_k127_7753249_3	1121422.AUMW01000009_gene3305	3.947e-36	138.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,266V3@186807|Peptococcaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
XH1_k127_7761201_3	279238.Saro_1300	1.412e-10	63.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2TRSH@28211|Alphaproteobacteria,2K159@204457|Sphingomonadales	204457|Sphingomonadales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
XH1_k127_7761201_1	56780.SYN_01605	4.194e-40	159.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,42SHU@68525|delta/epsilon subdivisions,2WPGG@28221|Deltaproteobacteria,2MRM8@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2,PDEase_II
XH1_k127_7761201_0	706587.Desti_1263	1.636e-80	283.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2MQDR@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Nucleotidyl transferase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
XH1_k127_7761201_2	335543.Sfum_3255	3.595e-35	149.0	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,42TNF@68525|delta/epsilon subdivisions,2WQ1R@28221|Deltaproteobacteria,2MRXW@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
XH1_k127_7762501_1	1304885.AUEY01000095_gene2617	2.145e-90	310.0	COG1148@1|root,COG1148@2|Bacteria,1N26U@1224|Proteobacteria,43BRJ@68525|delta/epsilon subdivisions,2X72E@28221|Deltaproteobacteria,2MPJ6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
XH1_k127_7762501_2	1347392.CCEZ01000021_gene849	3.091e-25	107.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,36MMP@31979|Clostridiaceae	186801|Clostridia	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
XH1_k127_7762501_4	335543.Sfum_1451	4.236e-08	59.0	2DD8H@1|root,2ZH1Z@2|Bacteria,1PBE0@1224|Proteobacteria,432B3@68525|delta/epsilon subdivisions,2WY4T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7762501_0	1245471.PCA10_44300	9.972e-92	310.0	COG4221@1|root,COG4221@2|Bacteria,1QTXD@1224|Proteobacteria,1T1MG@1236|Gammaproteobacteria,1YHE0@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
XH1_k127_7762501_3	177437.HRM2_16060	4.242e-13	69.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI0T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
XH1_k127_7796455_0	522306.CAP2UW1_3076	6.737e-136	439.0	COG0310@1|root,COG0310@2|Bacteria,1R70A@1224|Proteobacteria,2VS85@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cobalamin (Vitamin B12) biosynthesis CbiM protein	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
XH1_k127_7796455_2	269799.Gmet_2440	1.389e-85	291.0	COG0619@1|root,COG0619@2|Bacteria,1R2DN@1224|Proteobacteria,43B6A@68525|delta/epsilon subdivisions,2X6JT@28221|Deltaproteobacteria,43S05@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Cobalt transport protein	nikQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
XH1_k127_7796455_1	243231.GSU1281	7.657e-114	380.0	COG1122@1|root,COG1122@2|Bacteria,1N5X0@1224|Proteobacteria,43ADF@68525|delta/epsilon subdivisions,2WMEV@28221|Deltaproteobacteria,43T54@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	-	-	-	ko:K02006,ko:K16787	ko02010,map02010	M00245,M00246,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
XH1_k127_7812098_2	106370.Francci3_3235	3.294e-58	214.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,DUF3995
XH1_k127_7812098_1	479434.Sthe_2535	8.85e-109	364.0	COG1473@1|root,COG1473@2|Bacteria,2G5WT@200795|Chloroflexi,27XWM@189775|Thermomicrobia	200795|Chloroflexi	S	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
XH1_k127_7812098_3	706587.Desti_1456	2.705e-48	179.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
XH1_k127_7812098_0	909663.KI867150_gene1156	1.306e-159	512.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2MR9G@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
XH1_k127_7818109_3	1177181.T9A_02289	0.0001136	52.0	COG0739@1|root,COG3061@1|root,COG0739@2|Bacteria,COG3061@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XHD2@135619|Oceanospirillales	135619|Oceanospirillales	M	Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	OapA,Peptidase_M23
XH1_k127_7818109_1	1121918.ARWE01000001_gene3567	6.101e-73	260.0	COG0235@1|root,COG0235@2|Bacteria,1N84G@1224|Proteobacteria,42RVW@68525|delta/epsilon subdivisions,2WSI5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Class II aldolase	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
XH1_k127_7818109_0	404380.Gbem_3341	1.834e-166	542.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
XH1_k127_7818109_2	177437.HRM2_06850	2.728e-15	78.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,2MKX6@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
XH1_k127_7829240_1	96561.Dole_2179	1.661e-89	303.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2MHYZ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Carbamoyl-phosphate synthase L chain	pccA	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
XH1_k127_7829240_0	96561.Dole_2180	7.261e-258	803.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,42N6D@68525|delta/epsilon subdivisions,2X5IJ@28221|Deltaproteobacteria,2MN7B@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	-	-	6.4.1.4,6.4.1.5	ko:K01969,ko:K13778	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R03494,R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
XH1_k127_7829240_2	582515.KR51_00015920	1.197e-08	58.0	COG0438@1|root,COG0438@2|Bacteria,1G06H@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
XH1_k127_7844899_4	264732.Moth_1586	1.242e-23	102.0	COG2164@1|root,COG2164@2|Bacteria,1VHU9@1239|Firmicutes,24TQA@186801|Clostridia,42IM5@68295|Thermoanaerobacterales	186801|Clostridia	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
XH1_k127_7844899_3	517417.Cpar_0579	1.003e-28	118.0	COG1324@1|root,COG1324@2|Bacteria,1FFG3@1090|Chlorobi	1090|Chlorobi	P	PFAM CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
XH1_k127_7844899_5	940282.CADQ01000047_gene718	1.205e-08	65.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
XH1_k127_7844899_6	471856.Jden_1551	0.0006794	49.0	COG0613@1|root,COG0613@2|Bacteria,2GIZ5@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3097
XH1_k127_7844899_0	349521.HCH_02184	9.348e-210	673.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XHXE@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
XH1_k127_7844899_1	1499967.BAYZ01000050_gene2808	4.629e-164	525.0	COG1087@1|root,COG1087@2|Bacteria,2NNVI@2323|unclassified Bacteria	2|Bacteria	M	NAD(P)H-binding	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
XH1_k127_7844899_2	1304885.AUEY01000002_gene321	3.296e-91	304.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria,2MI3X@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
XH1_k127_7847560_8	349521.HCH_06807	3.843e-10	64.0	COG0834@1|root,COG0834@2|Bacteria,1R4SQ@1224|Proteobacteria,1RQ7A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
XH1_k127_7847560_7	314345.SPV1_00215	1.102e-13	75.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
XH1_k127_7847560_0	1307759.JOMJ01000003_gene517	1.197e-87	299.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2M8CF@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	heat shock protein DnaJ domain protein	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
XH1_k127_7847560_3	556268.OFAG_01705	2.386e-48	185.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,472D4@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
XH1_k127_7847560_1	1125863.JAFN01000001_gene3112	1.501e-65	240.0	28QK0@1|root,2ZD1U@2|Bacteria,1NFK4@1224|Proteobacteria,42VSJ@68525|delta/epsilon subdivisions,2WRIZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7847560_2	1125863.JAFN01000001_gene3040	4.49e-52	200.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
XH1_k127_7847560_6	880073.Calab_0100	3.706e-24	114.0	COG0123@1|root,COG0123@2|Bacteria,2NRDM@2323|unclassified Bacteria	2|Bacteria	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
XH1_k127_7847560_5	316067.Geob_0615	1.462e-39	155.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,43UT3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
XH1_k127_7847560_4	177437.HRM2_19680	3.207e-44	170.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,42QS3@68525|delta/epsilon subdivisions,2WMX0@28221|Deltaproteobacteria,2MJKR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31,CbiA,ParA
XH1_k127_7847560_10	765869.BDW_12230	0.0002703	51.0	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,437H8@68525|delta/epsilon subdivisions,2MTC0@213481|Bdellovibrionales,2X2QR@28221|Deltaproteobacteria	213481|Bdellovibrionales	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
XH1_k127_7847560_9	338966.Ppro_2879	0.0001504	52.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,43SAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	SMART AAA ATPase	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
XH1_k127_7900600_1	443143.GM18_0017	1.805e-82	286.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2WQTT@28221|Deltaproteobacteria,43VJV@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
XH1_k127_7900600_3	1095749.HMPREF1052_1314	1.437e-37	145.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1Y8WI@135625|Pasteurellales	135625|Pasteurellales	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
XH1_k127_7900600_2	485915.Dret_1643	7.974e-63	222.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2WVHB@28221|Deltaproteobacteria,2MGTD@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, crp family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
XH1_k127_7900600_0	439235.Dalk_5049	3.046e-100	336.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,42QRA@68525|delta/epsilon subdivisions,2WN1V@28221|Deltaproteobacteria,2MK22@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
XH1_k127_7900600_4	1232437.KL662010_gene1569	1.726e-34	137.0	COG1433@1|root,COG1433@2|Bacteria,1N56C@1224|Proteobacteria,42TK7@68525|delta/epsilon subdivisions,2WQ0G@28221|Deltaproteobacteria,2MKGU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
XH1_k127_7902704_3	96561.Dole_2001	9.254e-139	446.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42M9N@68525|delta/epsilon subdivisions,2WIZR@28221|Deltaproteobacteria,2MHKG@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
XH1_k127_7902704_6	1499967.BAYZ01000093_gene4022	8.568e-32	131.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
XH1_k127_7902704_2	96561.Dole_2003	9.93e-141	454.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,42MVD@68525|delta/epsilon subdivisions,2WIY3@28221|Deltaproteobacteria,2MIPS@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
XH1_k127_7902704_4	485915.Dret_1138	1.059e-57	205.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WNC2@28221|Deltaproteobacteria,2MBI7@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Amino acid-binding ACT	-	-	-	-	-	-	-	-	-	-	-	-	ACT
XH1_k127_7902704_0	639282.DEFDS_0964	4.676e-206	648.0	COG1541@1|root,COG1541@2|Bacteria,2GEXG@200930|Deferribacteres	200930|Deferribacteres	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
XH1_k127_7902704_5	338963.Pcar_1568	1.781e-51	188.0	COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,42SK4@68525|delta/epsilon subdivisions,2WPI8@28221|Deltaproteobacteria,43UPF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	iorB-1	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
XH1_k127_7902704_1	316067.Geob_2794	6.535e-191	609.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA-1	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
XH1_k127_7907977_16	448385.sce7260	6.95e-06	52.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,2YVS3@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
XH1_k127_7907977_13	1121423.JONT01000008_gene747	1.005e-39	155.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,261Z3@186807|Peptococcaceae	186801|Clostridia	H	PFAM Thiamin pyrophosphokinase, vitamin B1 binding domain	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
XH1_k127_7907977_11	1121441.AUCX01000002_gene2816	2.71e-63	223.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,42S4R@68525|delta/epsilon subdivisions,2WNE1@28221|Deltaproteobacteria,2MBJR@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
XH1_k127_7907977_9	96561.Dole_2108	1.91e-72	259.0	COG1234@1|root,COG1234@2|Bacteria,1PPRD@1224|Proteobacteria,42N8A@68525|delta/epsilon subdivisions,2WKHD@28221|Deltaproteobacteria,2MIHV@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
XH1_k127_7907977_0	1304875.JAFZ01000002_gene330	0.0	1044.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,3TBYB@508458|Synergistetes	508458|Synergistetes	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
XH1_k127_7907977_8	706587.Desti_2867	1.731e-83	290.0	28MQN@1|root,2ZAZG@2|Bacteria,1MVVQ@1224|Proteobacteria,42MMM@68525|delta/epsilon subdivisions,2WKA1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7907977_5	1192034.CAP_6873	6.76e-99	331.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,2YTZN@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1162	THF_DHG_CYH,THF_DHG_CYH_C
XH1_k127_7907977_6	714961.BFZC1_16934	6.765e-94	320.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,3IVVW@400634|Lysinibacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
XH1_k127_7907977_12	714961.BFZC1_09820	4.674e-40	152.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,3IXZI@400634|Lysinibacillus	91061|Bacilli	E	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate	gcvH	GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
XH1_k127_7907977_4	713586.KB900536_gene2603	1.659e-109	368.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria,1WWD2@135613|Chromatiales	135613|Chromatiales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
XH1_k127_7907977_2	246194.CHY_0492	3.462e-151	494.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia,42FHX@68295|Thermoanaerobacterales	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS11880	GDC-P
XH1_k127_7907977_14	945713.IALB_0483	4.14e-32	132.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_7907977_1	439235.Dalk_3322	1.576e-155	503.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WJS7@28221|Deltaproteobacteria,2MIWA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
XH1_k127_7907977_10	1172185.KB911516_gene2566	4.025e-66	233.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,4FXIS@85025|Nocardiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
XH1_k127_7907977_3	1304885.AUEY01000022_gene3411	6.174e-137	445.0	COG3387@1|root,COG3387@2|Bacteria,1NB01@1224|Proteobacteria,42N48@68525|delta/epsilon subdivisions,2WJRY@28221|Deltaproteobacteria,2MHXM@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7907977_7	1121405.dsmv_2235	8.107e-92	307.0	COG0110@1|root,COG0110@2|Bacteria,1N6SQ@1224|Proteobacteria,42PE2@68525|delta/epsilon subdivisions,2WKVK@28221|Deltaproteobacteria,2MJ81@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
XH1_k127_7911665_1	572546.Arcpr_1465	1.472e-33	140.0	COG0560@1|root,arCOG01158@2157|Archaea,2XT0C@28890|Euryarchaeota,2462F@183980|Archaeoglobi	183980|Archaeoglobi	E	phosphoserine phosphatase SerB	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
XH1_k127_7911665_2	96561.Dole_0270	5.112e-25	106.0	2DCYV@1|root,2ZFVG@2|Bacteria,1P7PB@1224|Proteobacteria,433JH@68525|delta/epsilon subdivisions,2WXCN@28221|Deltaproteobacteria,2MP6X@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7911665_0	1144275.COCOR_06119	3.987e-107	360.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42MBY@68525|delta/epsilon subdivisions,2WIR5@28221|Deltaproteobacteria,2YUKC@29|Myxococcales	28221|Deltaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.61	ko:K00043	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R01644	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
XH1_k127_7917695_3	158190.SpiGrapes_2707	1.801e-09	63.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_7917695_1	1265505.ATUG01000002_gene2637	8.078e-104	341.0	29CZA@1|root,2ZZXB@2|Bacteria,1RFNE@1224|Proteobacteria,42TRV@68525|delta/epsilon subdivisions,2WR3X@28221|Deltaproteobacteria,2MKTT@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7917695_2	479434.Sthe_2907	1.439e-59	208.0	COG2164@1|root,COG2164@2|Bacteria,2G8JQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3830)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3830
XH1_k127_7917695_0	1304885.AUEY01000031_gene51	0.0	1489.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2MI5E@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
XH1_k127_7921493_4	864563.HMPREF9166_0374	3.85e-106	357.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,4H25V@909932|Negativicutes	909932|Negativicutes	O	Peptidase U32	yhbU_2	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
XH1_k127_7921493_2	266117.Rxyl_0825	4.617e-151	514.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CPKC@84995|Rubrobacteria	84995|Rubrobacteria	L	COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
XH1_k127_7921493_6	247490.KSU1_C0836	4.521e-57	204.0	COG1704@1|root,COG1704@2|Bacteria,2IZBC@203682|Planctomycetes	203682|Planctomycetes	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
XH1_k127_7921493_7	247490.KSU1_C0835	3.296e-46	177.0	COG1512@1|root,COG1512@2|Bacteria,2J44M@203682|Planctomycetes	203682|Planctomycetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
XH1_k127_7921493_8	247490.KSU1_C0834	6.563e-35	146.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	KNTase_C,NTP_transf_2
XH1_k127_7921493_0	1125863.JAFN01000001_gene1462	3.288e-290	911.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
XH1_k127_7921493_1	1121918.ARWE01000001_gene2669	1.643e-178	586.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,43RXX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
XH1_k127_7921493_10	1260251.SPISAL_02990	0.0003759	49.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1WYDK@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
XH1_k127_7921493_9	443143.GM18_2668	1.785e-19	98.0	COG1381@1|root,COG1381@2|Bacteria	2|Bacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0008150,GO:0009314,GO:0009628,GO:0050896	2.6.99.2	ko:K03474,ko:K03584	ko00750,ko01100,ko03440,map00750,map01100,map03440	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	RecO_C,RecO_N
XH1_k127_7921493_3	56780.SYN_01536	5.044e-142	455.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2WJJW@28221|Deltaproteobacteria,2MQ4G@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	PFAM glycyl-tRNA synthetase, alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_2942	tRNA-synt_2e
XH1_k127_7921493_5	215803.DB30_1062	8.803e-79	284.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria,2YUNH@29|Myxococcales	28221|Deltaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
XH1_k127_7939870_0	1121448.DGI_1512	2.785e-108	357.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WIY9@28221|Deltaproteobacteria,2M914@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM ATP phosphoribosyltransferase, catalytic region	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
XH1_k127_7939870_1	1120973.AQXL01000112_gene1094	1.607e-94	316.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,277XD@186823|Alicyclobacillaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
XH1_k127_7939870_2	667014.Thein_1219	2.939e-94	325.0	COG2148@1|root,COG2148@2|Bacteria,2GHZH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
XH1_k127_7939870_3	933262.AXAM01000034_gene1565	2.845e-57	225.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2MJAV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8,zinc_ribbon_4
XH1_k127_7943850_4	696281.Desru_1017	2.913e-10	61.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,261RD@186807|Peptococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
XH1_k127_7943850_0	309803.CTN_1064	1.128e-190	606.0	COG0554@1|root,COG0554@2|Bacteria,2GC7B@200918|Thermotogae	200918|Thermotogae	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
XH1_k127_7943850_1	667014.Thein_1180	2.498e-85	290.0	COG0767@1|root,COG0767@2|Bacteria,2GH54@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
XH1_k127_7943850_2	1232437.KL661953_gene2314	3.611e-45	169.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2WNUH@28221|Deltaproteobacteria,2MJVE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	TIGRFAM thioredoxin	trx-3	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
XH1_k127_7943850_3	706587.Desti_2954	2.317e-12	70.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MR2Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
XH1_k127_7946210_17	338963.Pcar_2795	1.946e-24	104.0	COG0426@1|root,COG0426@2|Bacteria,1R4UD@1224|Proteobacteria,43AF5@68525|delta/epsilon subdivisions,2X5UW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	flavodoxin nitric oxide synthase	roo	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B,Lactamase_B_2
XH1_k127_7946210_18	880072.Desac_2169	7.941e-24	101.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,42VC4@68525|delta/epsilon subdivisions,2WRDM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rub	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	Rubredoxin
XH1_k127_7946210_3	933262.AXAM01000043_gene1184	3.313e-80	279.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,2MJJR@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
XH1_k127_7946210_13	439235.Dalk_4425	7.367e-42	159.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria,2MJZ5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_7946210_10	944481.JAFP01000001_gene423	1.248e-48	183.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2M734@213113|Desulfurellales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
XH1_k127_7946210_11	224325.AF_1199	1.432e-47	185.0	COG1788@1|root,arCOG01987@2157|Archaea,2XVRA@28890|Euryarchaeota,246WP@183980|Archaeoglobi	183980|Archaeoglobi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
XH1_k127_7946210_8	161156.JQKW01000013_gene149	7.944e-60	220.0	COG1463@1|root,COG1463@2|Bacteria,2GGR8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
XH1_k127_7946210_14	909663.KI867150_gene2934	2.58e-41	171.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2MR1G@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
XH1_k127_7946210_6	56780.SYN_01763	1.024e-68	240.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,2MQF1@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
XH1_k127_7946210_4	580327.Tthe_1526	1.272e-78	273.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,42FC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
XH1_k127_7946210_12	639282.DEFDS_0269	3.671e-42	163.0	COG0242@1|root,COG0242@2|Bacteria,2GFNS@200930|Deferribacteres	200930|Deferribacteres	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
XH1_k127_7946210_16	1157490.EL26_01000	8.959e-29	126.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,278BI@186823|Alicyclobacillaceae	91061|Bacilli	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
XH1_k127_7946210_5	706587.Desti_1666	9.727e-72	251.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42R4A@68525|delta/epsilon subdivisions,2WM9Z@28221|Deltaproteobacteria,2MRR8@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
XH1_k127_7946210_20	1121413.JMKT01000012_gene491	9.323e-12	74.0	COG2834@1|root,COG2834@2|Bacteria,1PDTV@1224|Proteobacteria,42TAB@68525|delta/epsilon subdivisions,2WPXY@28221|Deltaproteobacteria,2MA72@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
XH1_k127_7946210_0	316067.Geob_3802	2.037e-178	583.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,43UK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
XH1_k127_7946210_2	394503.Ccel_1772	2.163e-115	391.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,36DE5@31979|Clostridiaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
XH1_k127_7946210_15	526227.Mesil_0432	4.932e-29	131.0	COG0204@1|root,COG0204@2|Bacteria,1WJXG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
XH1_k127_7946210_9	96561.Dole_0983	7.624e-51	188.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2MJG9@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
XH1_k127_7946210_22	1304872.JAGC01000005_gene2162	0.0001663	49.0	COG4786@1|root,COG4786@2|Bacteria,1NC8Z@1224|Proteobacteria,42V6Q@68525|delta/epsilon subdivisions,2WRBM@28221|Deltaproteobacteria,2MD73@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Belongs to the flagella basal body rod proteins family	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
XH1_k127_7946210_7	1123376.AUIU01000016_gene231	1.269e-64	241.0	COG5002@1|root,COG5002@2|Bacteria,3J10G@40117|Nitrospirae	40117|Nitrospirae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
XH1_k127_7946210_1	1121440.AUMA01000011_gene2448	2.665e-119	398.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M2X@68525|delta/epsilon subdivisions,2WJMY@28221|Deltaproteobacteria,2M8ZP@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_794830_1	247490.KSU1_C0520	3.105e-92	314.0	COG0031@1|root,COG0031@2|Bacteria,2IXCX@203682|Planctomycetes	203682|Planctomycetes	E	cysteine synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
XH1_k127_794830_0	1499967.BAYZ01000079_gene883	3.379e-215	676.0	COG2873@1|root,COG2873@2|Bacteria,2NQN4@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
XH1_k127_794830_2	56780.SYN_01250	1.616e-61	216.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,43B10@68525|delta/epsilon subdivisions,2WPB0@28221|Deltaproteobacteria,2MRVY@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
XH1_k127_7956874_4	706587.Desti_3193	4.339e-60	212.0	2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria,42ZVK@68525|delta/epsilon subdivisions,2WV6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
XH1_k127_7956874_1	443254.Marpi_1839	2.987e-165	535.0	COG0513@1|root,COG0513@2|Bacteria,2GC3A@200918|Thermotogae	200918|Thermotogae	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
XH1_k127_7956874_0	56780.SYN_00538	1.672e-186	595.0	COG1032@1|root,COG1032@2|Bacteria,1PDZR@1224|Proteobacteria,42M73@68525|delta/epsilon subdivisions,2WK6Y@28221|Deltaproteobacteria,2MQ41@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
XH1_k127_7956874_9	1394178.AWOO02000038_gene9123	7.394e-09	69.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4EHRB@85012|Streptosporangiales	201174|Actinobacteria	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
XH1_k127_7956874_8	1121405.dsmv_1554	7.24e-10	63.0	COG1149@1|root,COG1149@2|Bacteria,1R0RE@1224|Proteobacteria,43CZP@68525|delta/epsilon subdivisions,2X87Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
XH1_k127_7956874_3	644282.Deba_3002	4.61e-75	272.0	COG1149@1|root,COG1149@2|Bacteria,1QYGR@1224|Proteobacteria,43CD0@68525|delta/epsilon subdivisions,2X7NV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
XH1_k127_7956874_5	1480694.DC28_14035	4.749e-39	154.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	nnrR	-	-	ko:K01420,ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
XH1_k127_7956874_2	1499967.BAYZ01000097_gene4328	5.303e-107	356.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	ydeD	-	-	-	-	-	-	-	-	-	-	-	EamA
XH1_k127_7956874_7	404380.Gbem_2787	5.528e-12	68.0	COG3620@1|root,COG3620@2|Bacteria,1N84U@1224|Proteobacteria,43BV6@68525|delta/epsilon subdivisions,2WSBR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
XH1_k127_7962672_2	457415.HMPREF1006_02047	7.347e-24	108.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
XH1_k127_7962672_1	457415.HMPREF1006_02038	2.251e-102	347.0	COG3875@1|root,COG3875@2|Bacteria,3TAE0@508458|Synergistetes	508458|Synergistetes	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
XH1_k127_7962672_0	647113.Metok_1158	5.85e-135	442.0	COG0148@1|root,arCOG01169@2157|Archaea,2XSXT@28890|Euryarchaeota,23QNJ@183939|Methanococci	183939|Methanococci	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
XH1_k127_7968658_3	269799.Gmet_2285	6.375e-37	152.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,42N0S@68525|delta/epsilon subdivisions,2WJR0@28221|Deltaproteobacteria,43SPE@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Probable RNA and SrmB- binding site of polymerase A	ccaC	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
XH1_k127_7968658_1	1232410.KI421412_gene107	1.214e-129	427.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria,43S7B@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Histidinol dehydrogenase	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
XH1_k127_7968658_0	743721.Psesu_1072	1.688e-141	460.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1X48Z@135614|Xanthomonadales	135614|Xanthomonadales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
XH1_k127_7968658_2	1265505.ATUG01000001_gene3377	4.742e-54	199.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2MHVH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
XH1_k127_7982708_1	485913.Krac_12542	2.001e-88	306.0	COG1063@1|root,COG1063@2|Bacteria,2G7NV@200795|Chloroflexi	200795|Chloroflexi	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
XH1_k127_7982708_2	644107.SL1157_0518	4.781e-08	54.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7982708_0	1197477.IA57_12080	1.826e-146	471.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,1HYAD@117743|Flavobacteriia	976|Bacteroidetes	C	NADH flavin oxidoreductase	nemA	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
XH1_k127_7999044_3	243231.GSU1594	1.133e-76	269.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42P7N@68525|delta/epsilon subdivisions,2WJKE@28221|Deltaproteobacteria,43TZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
XH1_k127_7999044_0	1131269.AQVV01000001_gene1389	1.488e-219	701.0	COG1185@1|root,COG1185@2|Bacteria	2|Bacteria	J	polyribonucleotide nucleotidyltransferase activity	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
XH1_k127_7999044_9	439235.Dalk_4742	1.146e-31	127.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2MKH5@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
XH1_k127_7999044_7	398767.Glov_1672	7.058e-45	180.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
XH1_k127_7999044_8	1341151.ASZU01000025_gene3004	2.893e-41	165.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,27BHU@186824|Thermoactinomycetaceae	91061|Bacilli	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
XH1_k127_7999044_11	56780.SYN_01785	2.013e-24	107.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,42VQ6@68525|delta/epsilon subdivisions,2WRTU@28221|Deltaproteobacteria,2MQNU@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
XH1_k127_7999044_12	575609.HMPREF0629_01410	2.854e-20	94.0	COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,24QJY@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
XH1_k127_7999044_1	246194.CHY_1766	2.26e-200	654.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,42EP2@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
XH1_k127_7999044_13	644966.Tmar_1017	1.476e-07	60.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3WCNN@538999|Clostridiales incertae sedis	186801|Clostridia	K	Protein of unknown function (DUF448)	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
XH1_k127_7999044_2	706587.Desti_3722	9.595e-129	423.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2MQWA@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
XH1_k127_7999044_10	644282.Deba_0888	2.84e-27	116.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
XH1_k127_7999044_6	2423.NA23_0204940	8.215e-51	183.0	COG0432@1|root,COG0432@2|Bacteria,2GD2P@200918|Thermotogae	200918|Thermotogae	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
XH1_k127_7999044_4	589865.DaAHT2_0558	2.016e-68	241.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2MIBY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
XH1_k127_7999044_5	338966.Ppro_0018	1.649e-66	235.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
XH1_k127_8000604_5	1232437.KL662034_gene2628	0.0003034	46.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42MTW@68525|delta/epsilon subdivisions,2WJ0J@28221|Deltaproteobacteria,2MIB0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
XH1_k127_8000604_3	316067.Geob_3095	2.655e-58	214.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42QX1@68525|delta/epsilon subdivisions,2WMNH@28221|Deltaproteobacteria,43TQD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
XH1_k127_8000604_2	398767.Glov_2734	1.069e-89	315.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
XH1_k127_8000604_0	1499967.BAYZ01000084_gene3994	5.823e-115	380.0	COG1186@1|root,COG1186@2|Bacteria,2NNU3@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
XH1_k127_8000604_1	933262.AXAM01000002_gene543	3.359e-108	362.0	COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,42P2H@68525|delta/epsilon subdivisions,2WJQM@28221|Deltaproteobacteria,2MI76@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TraB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TraB
XH1_k127_8000604_4	272560.BPSL2247	1.427e-11	72.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria,1K18M@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
XH1_k127_8029200_3	1261545.MBE-HAL_2000	1.766e-07	56.0	COG0346@1|root,arCOG02706@2157|Archaea,2XUR5@28890|Euryarchaeota,23UU2@183963|Halobacteria	183963|Halobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
XH1_k127_8029200_2	1128421.JAGA01000002_gene217	1.118e-88	305.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	fbpC	-	3.6.3.30,3.6.3.31	ko:K02010,ko:K02052,ko:K02062,ko:K11072	ko02010,ko02024,map02010,map02024	M00190,M00191,M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11,3.A.1.11.1,3.A.1.19	-	-	ABC_tran,TOBE_2
XH1_k127_8029200_0	177437.HRM2_22610	2.227e-164	533.0	COG1178@1|root,COG1178@2|Bacteria,1MWCF@1224|Proteobacteria,42PCF@68525|delta/epsilon subdivisions,2WKZ4@28221|Deltaproteobacteria,2MHZR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	BPD_transp_1
XH1_k127_8029200_1	177437.HRM2_22600	2.861e-131	428.0	COG4143@1|root,COG4143@2|Bacteria,1MUBB@1224|Proteobacteria,42PFS@68525|delta/epsilon subdivisions,2WIR3@28221|Deltaproteobacteria,2MI8U@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Bacterial extracellular solute-binding protein	-	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
XH1_k127_8050370_3	335543.Sfum_0326	2.549e-19	94.0	COG0790@1|root,COG0790@2|Bacteria,1PSBM@1224|Proteobacteria,42XTM@68525|delta/epsilon subdivisions,2WSIZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
XH1_k127_8050370_1	1128427.KB904821_gene3254	1.151e-39	167.0	COG5316@1|root,COG5316@2|Bacteria,1G2S6@1117|Cyanobacteria,1HA82@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
XH1_k127_8050370_4	56780.SYN_02339	2.712e-15	90.0	COG2197@1|root,COG2202@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria,1Q9SD@1224|Proteobacteria,42NUX@68525|delta/epsilon subdivisions,2WM09@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
XH1_k127_8050370_0	96561.Dole_0981	2.481e-42	176.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2MMQH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,sCache_2
XH1_k127_8050370_5	285535.JOEY01000035_gene3715	4.869e-06	49.0	COG0477@1|root,COG0477@2|Bacteria,2H6BY@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
XH1_k127_8050370_2	933262.AXAM01000002_gene526	1.201e-29	125.0	COG0768@1|root,COG0768@2|Bacteria,1R7A0@1224|Proteobacteria,42MJC@68525|delta/epsilon subdivisions,2WJZ2@28221|Deltaproteobacteria,2MJ2J@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein	pbp4	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
XH1_k127_8061481_0	309807.SRU_2422	1.018e-72	256.0	COG1257@1|root,COG1257@2|Bacteria,4NGN1@976|Bacteroidetes,1FJW8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Hydroxymethylglutaryl-coenzyme A reductase	hmgA	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
XH1_k127_8061481_1	1121935.AQXX01000081_gene1095	7.499e-68	237.0	COG0500@1|root,COG2226@2|Bacteria,1R7VM@1224|Proteobacteria,1SKGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
XH1_k127_8061481_2	926550.CLDAP_27170	9.217e-49	187.0	COG4690@1|root,COG4690@2|Bacteria,2G7Y7@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
XH1_k127_806311_2	177437.HRM2_36060	1.162e-113	373.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2MHM9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
XH1_k127_806311_14	986075.CathTA2_2514	6.054e-41	155.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli	91061|Bacilli	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
XH1_k127_806311_21	1321814.HMPREF9089_01105	1.458e-12	71.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,25X9Q@186806|Eubacteriaceae	186801|Clostridia	J	COG1841 Ribosomal protein L30 L7E	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
XH1_k127_806311_10	1304885.AUEY01000001_gene3231	4.17e-53	192.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2WNBN@28221|Deltaproteobacteria,2MHKK@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
XH1_k127_806311_15	429009.Adeg_1508	3.549e-40	151.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,42GIE@68295|Thermoanaerobacterales	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
XH1_k127_806311_9	1122602.ATXP01000001_gene913	1.671e-54	196.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,1W829@1268|Micrococcaceae	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
XH1_k127_806311_12	394503.Ccel_0772	4.915e-44	167.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,36I6W@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
XH1_k127_806311_20	335543.Sfum_1568	9.534e-25	104.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,2MS3E@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
XH1_k127_806311_4	177439.DP1136	2.089e-76	259.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2MJFM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
XH1_k127_806311_16	485916.Dtox_0297	1.971e-33	132.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,26260@186807|Peptococcaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
XH1_k127_806311_8	1525715.IX54_04530	9.749e-55	194.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2U743@28211|Alphaproteobacteria,2PWXB@265|Paracoccus	28211|Alphaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
XH1_k127_806311_19	644282.Deba_2929	2.071e-25	108.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2WR6G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
XH1_k127_806311_22	235909.GK0114	2.938e-05	53.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,1WGTD@129337|Geobacillus	91061|Bacilli	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
XH1_k127_806311_6	1293054.HSACCH_00068	7.019e-63	218.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3WAKN@53433|Halanaerobiales	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
XH1_k127_806311_3	555779.Dthio_PD0321	2.525e-85	287.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2WIU3@28221|Deltaproteobacteria,2M9HD@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
XH1_k127_806311_17	589865.DaAHT2_1447	9.551e-32	126.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,42TRE@68525|delta/epsilon subdivisions,2WQBH@28221|Deltaproteobacteria,2MKFE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
XH1_k127_806311_13	644282.Deba_2934	5.987e-43	158.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,42THY@68525|delta/epsilon subdivisions,2WQ0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
XH1_k127_806311_1	868864.Dester_0197	1.436e-114	374.0	COG0090@1|root,COG0090@2|Bacteria,2G3KP@200783|Aquificae	200783|Aquificae	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
XH1_k127_806311_18	671143.DAMO_0541	3.786e-27	121.0	COG0089@1|root,COG0089@2|Bacteria,2NPWC@2323|unclassified Bacteria	2|Bacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
XH1_k127_806311_7	589865.DaAHT2_1451	2.691e-57	205.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,42MPW@68525|delta/epsilon subdivisions,2WN96@28221|Deltaproteobacteria,2MJHZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
XH1_k127_806311_5	1121451.DESAM_22996	3.799e-67	234.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,2M9CC@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
XH1_k127_806311_11	1125863.JAFN01000001_gene3294	6.404e-49	175.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,42SE4@68525|delta/epsilon subdivisions,2WP4K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
XH1_k127_806311_0	335543.Sfum_1541	1.072e-218	682.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MQ8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
XH1_k127_8091135_11	1304885.AUEY01000065_gene1292	5.868e-49	182.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MI4U@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
XH1_k127_8091135_4	439235.Dalk_3107	3.041e-77	265.0	COG4122@1|root,COG4122@2|Bacteria,1N2AR@1224|Proteobacteria,42R09@68525|delta/epsilon subdivisions,2WMWB@28221|Deltaproteobacteria,2MJMI@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
XH1_k127_8091135_9	635013.TherJR_1511	6.703e-52	201.0	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,24B18@186801|Clostridia	186801|Clostridia	L	PALM domain HD hydrolase domain and	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
XH1_k127_8091135_16	82654.Pse7367_0262	1.458e-07	63.0	COG1357@1|root,COG1357@2|Bacteria,1GFCJ@1117|Cyanobacteria,1HG94@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
XH1_k127_8091135_13	1051501.AYTL01000030_gene2601	1.172e-32	131.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,1ZH3P@1386|Bacillus	91061|Bacilli	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
XH1_k127_8091135_6	373903.Hore_10020	6.225e-61	213.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,3WAMS@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
XH1_k127_8091135_1	269799.Gmet_1626	2.012e-187	592.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,43U14@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
XH1_k127_8091135_8	1123371.ATXH01000004_gene1796	6.173e-55	200.0	COG0307@1|root,COG0307@2|Bacteria,2GGV7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Lumazine binding domain	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
XH1_k127_8091135_3	338963.Pcar_1445	7.917e-99	335.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2WIP2@28221|Deltaproteobacteria,43T8J@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1624	RibD_C,dCMP_cyt_deam_1
XH1_k127_8091135_10	706587.Desti_1157	9.031e-51	184.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,2MRQF@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
XH1_k127_8091135_0	639282.DEFDS_0485	5.663e-197	620.0	COG0112@1|root,COG0112@2|Bacteria,2GERI@200930|Deferribacteres	200930|Deferribacteres	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
XH1_k127_8091135_12	648996.Theam_1218	1.644e-47	176.0	COG0698@1|root,COG0698@2|Bacteria,2G43P@200783|Aquificae	200783|Aquificae	G	ribose 5-phosphate isomerase B	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
XH1_k127_8091135_2	997346.HMPREF9374_0894	8.146e-135	440.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,27B4D@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
XH1_k127_8091135_14	639282.DEFDS_0153	9.558e-22	96.0	COG0236@1|root,COG0236@2|Bacteria,2GG1C@200930|Deferribacteres	200930|Deferribacteres	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
XH1_k127_8091135_5	59919.PMM0453	2.079e-69	243.0	COG1028@1|root,COG1028@2|Bacteria,1G0MD@1117|Cyanobacteria,1MKQB@1212|Prochloraceae	1117|Cyanobacteria	IQ	Alternative locus ID	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
XH1_k127_8091135_7	1347369.CCAD010000041_gene778	4.351e-57	210.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,1ZBGQ@1386|Bacillus	91061|Bacilli	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
XH1_k127_8091135_15	316067.Geob_2610	3.979e-15	75.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,43SSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
XH1_k127_8132796_4	290317.Cpha266_1237	5.792e-06	49.0	COG0546@1|root,COG0546@2|Bacteria,1FE0Y@1090|Chlorobi	1090|Chlorobi	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
XH1_k127_8132796_2	909663.KI867150_gene307	4.484e-73	252.0	COG1811@1|root,COG1811@2|Bacteria,1MX1D@1224|Proteobacteria,42S9G@68525|delta/epsilon subdivisions,2WNUQ@28221|Deltaproteobacteria,2MQH1@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
XH1_k127_8132796_3	289377.HL41_05825	3.91e-41	158.0	COG1335@1|root,COG1335@2|Bacteria,2GHEA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
XH1_k127_8132796_0	667014.Thein_2095	4.913e-104	345.0	COG0052@1|root,COG0052@2|Bacteria,2GHHG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
XH1_k127_8132796_1	555088.DealDRAFT_2402	1.862e-74	256.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42JIE@68298|Syntrophomonadaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
XH1_k127_8219887_0	509191.AEDB02000018_gene239	4.753e-306	975.0	COG0493@1|root,COG4624@1|root,COG0493@2|Bacteria,COG4624@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WHYH@541000|Ruminococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Pyr_redox_2,Pyr_redox_3
XH1_k127_8219887_4	553973.CLOHYLEM_04993	1.019e-17	86.0	COG1905@1|root,COG1905@2|Bacteria,1VFEK@1239|Firmicutes,24QMM@186801|Clostridia,220WH@1506553|Lachnoclostridium	186801|Clostridia	C	Thioredoxin-like [2Fe-2S] ferredoxin	fhmD	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
XH1_k127_8219887_1	340099.Teth39_0221	3.333e-140	464.0	COG1145@1|root,COG3290@1|root,COG4624@1|root,COG1145@2|Bacteria,COG3290@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,25IYK@186801|Clostridia,42F3K@68295|Thermoanaerobacterales	186801|Clostridia	CT	4Fe-4S ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,PAS
XH1_k127_8219887_2	580331.Thit_2174	2.052e-87	302.0	COG2208@1|root,COG2208@2|Bacteria,1TQUC@1239|Firmicutes,248FZ@186801|Clostridia,42ENE@68295|Thermoanaerobacterales	186801|Clostridia	KT	PFAM Sporulation stage II, protein E C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
XH1_k127_8219887_3	880073.Calab_1426	9.456e-24	109.0	COG4191@1|root,COG4624@1|root,COG4191@2|Bacteria,COG4624@2|Bacteria,2NP4X@2323|unclassified Bacteria	2|Bacteria	C	Putative Fe-S cluster	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,HAMP,HATPase_c,HTH_8,HisKA,PAS_9,Sigma54_activat
XH1_k127_8235706_0	439235.Dalk_0164	0.0	1210.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria	1224|Proteobacteria	C	formate C-acetyltransferase glycine radical	-	-	-	-	-	-	-	-	-	-	-	-	PFL-like
XH1_k127_8235706_4	1123274.KB899408_gene3852	7.097e-33	138.0	COG2186@1|root,COG2186@2|Bacteria,2J8F7@203691|Spirochaetes	203691|Spirochaetes	K	Transcriptional regulator, GntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,FadR_C,GntR
XH1_k127_8235706_2	177437.HRM2_29270	4.383e-84	287.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,42QU2@68525|delta/epsilon subdivisions,2WMSF@28221|Deltaproteobacteria,2MJJF@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_8235706_1	269799.Gmet_0767	1.279e-225	717.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,42MTV@68525|delta/epsilon subdivisions,2WKVP@28221|Deltaproteobacteria,43S8J@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
XH1_k127_8235706_3	1382356.JQMP01000004_gene499	2.744e-57	211.0	COG1063@1|root,COG1063@2|Bacteria,2G7NV@200795|Chloroflexi,27Y3N@189775|Thermomicrobia	189775|Thermomicrobia	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
XH1_k127_8253294_0	192952.MM_0619	1.095e-214	687.0	COG1331@1|root,arCOG02007@2157|Archaea,2XU5Q@28890|Euryarchaeota,2N91Y@224756|Methanomicrobia	224756|Methanomicrobia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
XH1_k127_8253294_6	485915.Dret_1194	1.083e-85	293.0	COG0679@1|root,COG0679@2|Bacteria,1RAR6@1224|Proteobacteria,42R7S@68525|delta/epsilon subdivisions,2WN3D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
XH1_k127_8253294_2	1123371.ATXH01000022_gene974	1.016e-157	511.0	COG0606@1|root,COG0606@2|Bacteria,2GGU0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
XH1_k127_8253294_4	1121918.ARWE01000001_gene934	9.148e-122	398.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,43S3H@69541|Desulfuromonadales	28221|Deltaproteobacteria	EF	Phosphoribosyl synthetase-associated domain	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
XH1_k127_8253294_8	264462.Bd2801	4.154e-29	118.0	COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2MU0J@213481|Bdellovibrionales,2WQYK@28221|Deltaproteobacteria	213481|Bdellovibrionales	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
XH1_k127_8253294_7	439235.Dalk_3377	2.816e-49	186.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MJU3@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
XH1_k127_8253294_3	880072.Desac_1034	5.844e-130	431.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQB7@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
XH1_k127_8253294_9	667014.Thein_1529	2.919e-16	84.0	2EAFJ@1|root,334IY@2|Bacteria,2GHZR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
XH1_k127_8253294_5	269799.Gmet_1739	1.772e-89	310.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,43TQX@69541|Desulfuromonadales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
XH1_k127_8253294_10	439235.Dalk_0298	7.309e-13	70.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK05@28221|Deltaproteobacteria,2MHS3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
XH1_k127_8253294_1	439235.Dalk_0298	5.454e-197	626.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK05@28221|Deltaproteobacteria,2MHS3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
XH1_k127_8277093_5	525904.Tter_2868	6.011e-26	115.0	COG5002@1|root,COG5002@2|Bacteria,2NNKK@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K02484,ko:K07636,ko:K07768	ko02020,map02020	M00434,M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
XH1_k127_8277093_2	871963.Desdi_2794	1.117e-62	224.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
XH1_k127_8277093_4	56780.SYN_00054	1.234e-49	184.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42SQK@68525|delta/epsilon subdivisions,2WPK1@28221|Deltaproteobacteria,2MS9M@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
XH1_k127_8277093_0	909663.KI867150_gene525	2.716e-214	679.0	COG0642@1|root,COG1762@1|root,COG1762@2|Bacteria,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria,2MQ4A@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Osmosensitive K channel His kinase sensor	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	KdpD,PTS_EIIA_2,Usp
XH1_k127_8277093_3	706587.Desti_1869	9.918e-59	221.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,42SC9@68525|delta/epsilon subdivisions,2WPDZ@28221|Deltaproteobacteria,2MQQ6@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
XH1_k127_8277093_1	909663.KI867150_gene527	1.287e-197	621.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,42NGX@68525|delta/epsilon subdivisions,2WJC0@28221|Deltaproteobacteria,2MQBK@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAF987.Gmet_2434	E1-E2_ATPase,Hydrolase
XH1_k127_8284212_7	1286171.EAL2_c14390	5.896e-22	105.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,25VA3@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
XH1_k127_8284212_1	644282.Deba_0502	9.582e-142	477.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,42M42@68525|delta/epsilon subdivisions,2WM5M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
XH1_k127_8284212_4	909663.KI867150_gene405	1.999e-70	249.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,42QPY@68525|delta/epsilon subdivisions,2WMQC@28221|Deltaproteobacteria,2MQD4@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	PFAM Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
XH1_k127_8284212_3	335543.Sfum_2789	1.921e-104	357.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2MQ7N@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
XH1_k127_8284212_5	257310.BB3037	3.885e-44	165.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,3T3TE@506|Alcaligenaceae	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
XH1_k127_8284212_0	1121405.dsmv_3335	8.867e-155	515.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2WJEB@28221|Deltaproteobacteria,2MJ3Q@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
XH1_k127_8284212_2	909663.KI867150_gene1667	6.554e-124	410.0	COG3206@1|root,COG3206@2|Bacteria,1QUY4@1224|Proteobacteria,42RD1@68525|delta/epsilon subdivisions,2WMV4@28221|Deltaproteobacteria,2MQDI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
XH1_k127_8284212_6	909663.KI867150_gene2050	1.517e-36	150.0	2FISY@1|root,34AIH@2|Bacteria,1P2DJ@1224|Proteobacteria,431M3@68525|delta/epsilon subdivisions,2WWF4@28221|Deltaproteobacteria,2MS4C@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8304338_2	596151.DesfrDRAFT_1297	1.037e-50	187.0	COG2203@1|root,COG2203@2|Bacteria,1RHTM@1224|Proteobacteria,42SY3@68525|delta/epsilon subdivisions,2WP4G@28221|Deltaproteobacteria,2MADU@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM GAF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
XH1_k127_8304338_1	335543.Sfum_1468	4.105e-149	480.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2WIK1@28221|Deltaproteobacteria,2MRGN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
XH1_k127_8304338_0	56780.SYN_02589	0.0	1718.0	COG0458@1|root,COG0458@2|Bacteria,1NPMZ@1224|Proteobacteria,42NF3@68525|delta/epsilon subdivisions,2WM4C@28221|Deltaproteobacteria,2MQ8X@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain, oligomerisation	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0661	CPSase_L_D2,CPSase_L_D3,MGS
XH1_k127_8304338_3	96561.Dole_3119	6.985e-28	116.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_synthase
XH1_k127_8314106_1	335543.Sfum_2230	2.769e-63	225.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2MRQ4@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8314106_0	565033.GACE_1287	2.632e-69	243.0	COG1024@1|root,arCOG00239@2157|Archaea,2Y2NP@28890|Euryarchaeota,246M0@183980|Archaeoglobi	183980|Archaeoglobi	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_8314106_2	641524.ADICYQ_2642	5.515e-45	170.0	COG5523@1|root,COG5523@2|Bacteria,4NTWR@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
XH1_k127_8314106_3	710686.Mycsm_05821	3.129e-11	70.0	COG1309@1|root,COG1309@2|Bacteria,2HK4X@201174|Actinobacteria,234WZ@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcriptional	kstR2	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0042803,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22108	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
XH1_k127_8353190_0	886293.Sinac_2420	0.0	1029.0	COG0542@1|root,COG0542@2|Bacteria,2IWVE@203682|Planctomycetes	203682|Planctomycetes	O	TIGRFAM type VI secretion ATPase, ClpV1 family	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
XH1_k127_8373117_13	1448139.AI20_20010	2.025e-05	51.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,1Y3K0@135624|Aeromonadales	135624|Aeromonadales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
XH1_k127_8373117_7	1227352.C173_08181	4.123e-78	269.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,26QBT@186822|Paenibacillaceae	91061|Bacilli	S	Protein containing tetrapyrrole methyltransferase domain and MazG-like	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
XH1_k127_8373117_0	1499967.BAYZ01000117_gene3327	2.685e-184	588.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM-2	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
XH1_k127_8373117_12	1121440.AUMA01000009_gene559	1.403e-21	97.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,42V85@68525|delta/epsilon subdivisions,2WR93@28221|Deltaproteobacteria,2MDHT@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
XH1_k127_8373117_9	767817.Desgi_1808	5.381e-44	175.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,24BDQ@186801|Clostridia,261Z4@186807|Peptococcaceae	186801|Clostridia	S	Zn-dependent hydrolase, glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
XH1_k127_8373117_10	665571.STHERM_c07820	4.83e-43	164.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	metW	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	MetW
XH1_k127_8373117_1	234267.Acid_1433	1.283e-120	404.0	COG2021@1|root,COG2021@2|Bacteria,3Y4EW@57723|Acidobacteria	57723|Acidobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
XH1_k127_8373117_11	1410626.JHXB01000003_gene1084	4.629e-28	117.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,27NRG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
XH1_k127_8373117_4	203119.Cthe_0901	7.616e-97	324.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,3WHX6@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
XH1_k127_8373117_5	391625.PPSIR1_41464	3.671e-93	316.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2YU2N@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
XH1_k127_8373117_6	269799.Gmet_1782	1.544e-84	287.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,43TDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
XH1_k127_8373117_8	335543.Sfum_2337	9.002e-56	202.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,42SGK@68525|delta/epsilon subdivisions,2WPDI@28221|Deltaproteobacteria,2MS7N@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_4,Abhydrolase_5,DLH
XH1_k127_8373117_3	926550.CLDAP_04910	5.509e-107	357.0	COG0837@1|root,COG0837@2|Bacteria,2G7R9@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
XH1_k127_8373117_2	518766.Rmar_0472	3.816e-118	384.0	COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,1FIXF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Transketolase, thiamine diphosphate binding domain	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
XH1_k127_8393370_2	555079.Toce_2133	5.556e-74	255.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,42F6G@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
XH1_k127_8393370_0	56780.SYN_00940	6.518e-102	347.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
XH1_k127_8393370_1	335543.Sfum_2574	1.561e-91	313.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7Z@28221|Deltaproteobacteria,2MQJH@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
XH1_k127_8393370_3	1121423.JONT01000002_gene2292	1.408e-32	133.0	COG0778@1|root,COG0778@2|Bacteria,1V0Y6@1239|Firmicutes,24HMV@186801|Clostridia,261V8@186807|Peptococcaceae	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
XH1_k127_8397489_11	96561.Dole_2681	1.35e-32	132.0	COG3613@1|root,COG3613@2|Bacteria,1N451@1224|Proteobacteria,430HN@68525|delta/epsilon subdivisions,2WVQY@28221|Deltaproteobacteria,2MNRH@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
XH1_k127_8397489_1	305900.GV64_24305	6.294e-98	330.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,1XJ5B@135619|Oceanospirillales	135619|Oceanospirillales	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
XH1_k127_8397489_3	382245.ASA_0117	3.501e-92	314.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,1Y3K0@135624|Aeromonadales	135624|Aeromonadales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
XH1_k127_8397489_4	1192034.CAP_4530	2.798e-79	280.0	COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,42S9Z@68525|delta/epsilon subdivisions,2WUXI@28221|Deltaproteobacteria,2YUKK@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
XH1_k127_8397489_2	335543.Sfum_0500	1.989e-92	309.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,2MSCP@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
XH1_k127_8397489_7	1121438.JNJA01000009_gene4185	1.101e-42	164.0	COG0500@1|root,COG2226@2|Bacteria,1N3WC@1224|Proteobacteria,42URQ@68525|delta/epsilon subdivisions,2WQGW@28221|Deltaproteobacteria,2MCVU@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
XH1_k127_8397489_0	439235.Dalk_2461	3.988e-134	439.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,43BF7@68525|delta/epsilon subdivisions,2X6TK@28221|Deltaproteobacteria,2MIQS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
XH1_k127_8397489_12	264462.Bd2766	1.717e-31	133.0	COG3773@1|root,COG3773@2|Bacteria	2|Bacteria	M	sporulation resulting in formation of a cellular spore	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2,PG_binding_1
XH1_k127_8397489_9	1454004.AW11_02613	7.698e-36	141.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
XH1_k127_8397489_13	643648.Slip_1057	2.795e-30	131.0	COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1V9ZW@1239|Firmicutes,25AZU@186801|Clostridia	186801|Clostridia	M	NlpC p60 family	spr	-	-	ko:K19224,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60,SH3_3
XH1_k127_8397489_8	909663.KI867149_gene3356	2.012e-38	148.0	COG3824@1|root,COG3824@2|Bacteria,1R1JS@1224|Proteobacteria,43EIB@68525|delta/epsilon subdivisions,2X8GN@28221|Deltaproteobacteria,2MSGA@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
XH1_k127_8397489_17	717231.Flexsi_0508	1.721e-11	68.0	2AC7G@1|root,311S6@2|Bacteria,2GG6V@200930|Deferribacteres	200930|Deferribacteres	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8397489_5	706587.Desti_3718	2.389e-75	276.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
XH1_k127_8397489_14	641524.ADICYQ_5846	8.652e-24	106.0	COG1525@1|root,COG1525@2|Bacteria,4NT3S@976|Bacteroidetes,47RZB@768503|Cytophagia	976|Bacteroidetes	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
XH1_k127_8397489_15	1123371.ATXH01000016_gene1818	2.143e-22	106.0	COG2204@1|root,COG2204@2|Bacteria,2GHIR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_8397489_10	1124982.MSI_18710	2.423e-35	153.0	COG0455@1|root,COG0455@2|Bacteria,2J5B7@203691|Spirochaetes	203691|Spirochaetes	D	Belongs to the ParA family	fleN	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
XH1_k127_8397489_6	204669.Acid345_2697	2.507e-43	163.0	COG0249@1|root,COG0249@2|Bacteria,3Y2J5@57723|Acidobacteria,2JHTC@204432|Acidobacteriia	204432|Acidobacteriia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
XH1_k127_841115_3	56780.SYN_02923	2.842e-153	499.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2MQ67@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
XH1_k127_841115_2	56780.SYN_02960	1.67e-165	530.0	COG1207@1|root,COG1207@2|Bacteria,1R7DE@1224|Proteobacteria,42N1D@68525|delta/epsilon subdivisions,2WIRZ@28221|Deltaproteobacteria,2MQAT@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	-	-	2.7.7.23,2.7.7.83	ko:K00972	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	-
XH1_k127_841115_1	335543.Sfum_2913	2.479e-239	745.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria,2MQ5D@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1886	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
XH1_k127_841115_4	909663.KI867150_gene648	2.932e-137	443.0	COG0363@1|root,COG0363@2|Bacteria,1MVEA@1224|Proteobacteria,42NH0@68525|delta/epsilon subdivisions,2WM42@28221|Deltaproteobacteria,2MQ9S@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
XH1_k127_841115_0	56780.SYN_01625	0.0	1538.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2MRBU@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
XH1_k127_841115_5	1235792.C808_03210	0.0002798	43.0	COG1943@1|root,COG1943@2|Bacteria,1V3YY@1239|Firmicutes,24IB0@186801|Clostridia,27TKP@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
XH1_k127_8457191_1	398767.Glov_0049	2.307e-77	270.0	COG3481@1|root,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria,43T29@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	nucleic acid binding OB-fold tRNA helicase-type	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
XH1_k127_8457191_0	1232410.KI421428_gene1165	2.828e-110	362.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,43S1V@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
XH1_k127_8473170_1	1499967.BAYZ01000030_gene1176	2.625e-122	422.0	COG1033@1|root,COG1033@2|Bacteria,2NQ2I@2323|unclassified Bacteria	2|Bacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	LolA_like,MMPL,Polyketide_cyc2
XH1_k127_8473170_0	96561.Dole_1246	2.92e-219	695.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria,2MIWR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
XH1_k127_8473170_5	177437.HRM2_02900	1.472e-50	184.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria,2MIWR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
XH1_k127_8473170_3	439235.Dalk_3870	6.993e-84	286.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,Fer4_7
XH1_k127_8473170_6	439235.Dalk_3791	1.439e-47	180.0	2DNNY@1|root,32YCS@2|Bacteria,1NDIA@1224|Proteobacteria,4314H@68525|delta/epsilon subdivisions,2WX5B@28221|Deltaproteobacteria,2MNZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8473170_4	439235.Dalk_4703	3.383e-61	220.0	COG0300@1|root,COG0300@2|Bacteria,1QV54@1224|Proteobacteria,42UFF@68525|delta/epsilon subdivisions,2WQJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.105	ko:K15734	ko00830,map00830	-	R02124	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
XH1_k127_8473170_7	909663.KI867149_gene3173	4.26e-35	149.0	COG2197@1|root,COG2208@1|root,COG2197@2|Bacteria,COG2208@2|Bacteria,1R3YQ@1224|Proteobacteria,42N0Q@68525|delta/epsilon subdivisions,2WM6W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_4,PAS_9
XH1_k127_8473170_8	555088.DealDRAFT_0867	6.473e-27	124.0	COG3322@1|root,COG3437@1|root,COG3322@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,42KBX@68298|Syntrophomonadaceae	186801|Clostridia	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_3,PAS_4,PAS_9
XH1_k127_8473170_2	1202962.KB907184_gene242	1.571e-111	373.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RRA4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
XH1_k127_8473170_10	378806.STAUR_0278	6.594e-10	68.0	COG1309@1|root,COG1309@2|Bacteria,1RE97@1224|Proteobacteria,430U2@68525|delta/epsilon subdivisions,2WW4Q@28221|Deltaproteobacteria,2YWUX@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_8473170_9	96561.Dole_0041	1.275e-26	113.0	COG1960@1|root,COG1960@2|Bacteria,1R59X@1224|Proteobacteria,42P22@68525|delta/epsilon subdivisions,2WKQN@28221|Deltaproteobacteria,2MJCR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_8517561_5	96561.Dole_2391	3.291e-45	167.0	COG2334@1|root,COG2334@2|Bacteria,1RBUF@1224|Proteobacteria,42R0R@68525|delta/epsilon subdivisions,2WMR4@28221|Deltaproteobacteria,2MJPB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Choline/ethanolamine kinase	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
XH1_k127_8517561_0	522306.CAP2UW1_1124	1.518e-273	850.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,2VJKF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
XH1_k127_8517561_4	1217718.ALOU01000009_gene1000	7.052e-56	207.0	COG2067@1|root,COG2067@2|Bacteria,1RJIQ@1224|Proteobacteria,2WFUS@28216|Betaproteobacteria,1KA6V@119060|Burkholderiaceae	28216|Betaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8517561_1	555088.DealDRAFT_2538	1.493e-216	687.0	COG1960@1|root,COG1960@2|Bacteria,1V03D@1239|Firmicutes,24A8N@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
XH1_k127_8517561_2	439235.Dalk_1180	1.644e-128	456.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
XH1_k127_8517561_3	96561.Dole_1470	3.354e-114	398.0	COG0457@1|root,COG2203@1|root,COG2204@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43BR8@68525|delta/epsilon subdivisions,2X724@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
XH1_k127_8527341_7	706587.Desti_4591	2.067e-41	160.0	COG3303@1|root,COG3303@2|Bacteria,1QX6Q@1224|Proteobacteria,42MHA@68525|delta/epsilon subdivisions,2WMF3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
XH1_k127_8527341_3	290315.Clim_0454	3.93e-92	308.0	COG4420@1|root,COG4420@2|Bacteria,1FFB9@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
XH1_k127_8527341_6	1304885.AUEY01000017_gene3764	2.56e-64	225.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,43AE6@68525|delta/epsilon subdivisions,2X6A8@28221|Deltaproteobacteria,2MPXN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
XH1_k127_8527341_2	443254.Marpi_0643	7.635e-119	395.0	COG0477@1|root,COG2814@2|Bacteria,2GC8X@200918|Thermotogae	200918|Thermotogae	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
XH1_k127_8527341_8	43229.XP_007722632.1	3.51e-08	58.0	28NFY@1|root,2QV1J@2759|Eukaryota,39S95@33154|Opisthokonta,3P178@4751|Fungi,3QPCT@4890|Ascomycota	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
XH1_k127_8527341_9	1499967.BAYZ01000043_gene2285	2.712e-05	53.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
XH1_k127_8527341_0	439235.Dalk_3213	6.474e-220	697.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2MHUE@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
XH1_k127_8527341_1	1121405.dsmv_2603	3.131e-149	480.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42M4Y@68525|delta/epsilon subdivisions,2WKKD@28221|Deltaproteobacteria,2MIK0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
XH1_k127_8527341_5	1232437.KL661967_gene5078	2.585e-70	250.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,42MK2@68525|delta/epsilon subdivisions,2WMB3@28221|Deltaproteobacteria,2MIIM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
XH1_k127_8527341_4	1304885.AUEY01000021_gene3450	9.777e-78	273.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,42RXR@68525|delta/epsilon subdivisions,2WNHV@28221|Deltaproteobacteria,2MK34@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
XH1_k127_8528580_1	439235.Dalk_3448	8.062e-157	507.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NMZ@68525|delta/epsilon subdivisions,2WIZ0@28221|Deltaproteobacteria,2MINS@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
XH1_k127_8528580_0	338963.Pcar_2315	0.0	1109.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,43S3P@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Valyl tRNA synthetase tRNA binding arm	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
XH1_k127_8528580_3	523850.TON_0902	9.15e-30	128.0	COG0340@1|root,arCOG01940@2157|Archaea,2XSZ5@28890|Euryarchaeota,243TN@183968|Thermococci	183968|Thermococci	H	Biotin protein ligase C terminal domain	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
XH1_k127_8528580_2	648996.Theam_1607	9.045e-37	144.0	COG1499@1|root,COG1499@2|Bacteria,2G444@200783|Aquificae	200783|Aquificae	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	NMD3
XH1_k127_8528580_5	1462526.BN990_00609	1.255e-19	98.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,4HGXQ@91061|Bacilli,4C6AS@84406|Virgibacillus	91061|Bacilli	G	YdjC-like protein	celCD	-	2.7.1.196,2.7.1.205,3.5.1.105	ko:K02759,ko:K03478	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	YdjC
XH1_k127_8528580_4	768710.DesyoDRAFT_4281	2.956e-24	106.0	arCOG15062@1|root,32Y8D@2|Bacteria,1VEUQ@1239|Firmicutes,24TKJ@186801|Clostridia,262D1@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PQ-loop
XH1_k127_8534402_11	439235.Dalk_3776	0.0006068	47.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MI0N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_8534402_7	1121405.dsmv_0423	2.607e-42	162.0	COG1426@1|root,COG1917@1|root,COG1426@2|Bacteria,COG1917@2|Bacteria,1QWMR@1224|Proteobacteria,43BSQ@68525|delta/epsilon subdivisions,2X73G@28221|Deltaproteobacteria,2MPJK@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_31
XH1_k127_8534402_5	1207075.PputUW4_04192	3.995e-51	196.0	COG1403@1|root,COG1403@2|Bacteria,1RATU@1224|Proteobacteria,1SC8S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	5-methylcytosine-specific restriction enzyme	mcrA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008327,GO:0036094,GO:0043565,GO:0097159,GO:1901265,GO:1901363	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
XH1_k127_8534402_4	96561.Dole_1523	9.707e-87	295.0	COG0655@1|root,COG0655@2|Bacteria,1RCDV@1224|Proteobacteria,42R2V@68525|delta/epsilon subdivisions,2WN0P@28221|Deltaproteobacteria,2MJJM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
XH1_k127_8534402_8	1121939.L861_09960	1.082e-15	83.0	2EAYI@1|root,334ZG@2|Bacteria,1N8W1@1224|Proteobacteria,1SDMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8534402_9	566466.NOR53_2221	3.186e-07	61.0	COG3063@1|root,COG3063@2|Bacteria,1PF7F@1224|Proteobacteria,1SWSG@1236|Gammaproteobacteria,1J91V@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
XH1_k127_8534402_10	944479.JQLX01000013_gene1275	6.775e-05	53.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,42NEZ@68525|delta/epsilon subdivisions,2WJ5R@28221|Deltaproteobacteria,2M6AP@213113|Desulfurellales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
XH1_k127_8534402_6	338963.Pcar_0909	1.317e-42	169.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,42N9R@68525|delta/epsilon subdivisions,2WN5P@28221|Deltaproteobacteria,43S74@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
XH1_k127_8534402_3	398767.Glov_2628	9.172e-90	308.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,42NEZ@68525|delta/epsilon subdivisions,2WJ5R@28221|Deltaproteobacteria,43U4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
XH1_k127_8534402_2	667014.Thein_0859	3.22e-98	332.0	COG0820@1|root,COG0820@2|Bacteria,2GGZB@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
XH1_k127_8534402_0	56780.SYN_02573	7.194e-163	521.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria,2MR3A@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
XH1_k127_8534402_1	56780.SYN_02572	3.766e-128	415.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42MTW@68525|delta/epsilon subdivisions,2WJ0J@28221|Deltaproteobacteria,2MRC6@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
XH1_k127_8574421_1	909663.KI867149_gene3357	2.726e-77	264.0	COG2403@1|root,COG2403@2|Bacteria,1MV4C@1224|Proteobacteria,42NE0@68525|delta/epsilon subdivisions,2WJ94@28221|Deltaproteobacteria,2MQ51@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8574421_2	706587.Desti_4763	8.099e-23	109.0	COG3025@1|root,COG3025@2|Bacteria	2|Bacteria	S	triphosphatase activity	ygiF	-	3.6.1.25	ko:K18446	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,CYTH
XH1_k127_8574421_0	335543.Sfum_2333	1.863e-110	373.0	COG0534@1|root,COG0534@2|Bacteria,1NS6X@1224|Proteobacteria,42MWN@68525|delta/epsilon subdivisions,2WMPY@28221|Deltaproteobacteria,2MQVZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
XH1_k127_8574791_8	335543.Sfum_1870	9.669e-60	211.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
XH1_k127_8574791_1	1304885.AUEY01000024_gene2700	5.776e-199	626.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42NH6@68525|delta/epsilon subdivisions,2WJCV@28221|Deltaproteobacteria,2MHTU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
XH1_k127_8574791_4	1304885.AUEY01000029_gene2498	1.854e-95	318.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria,2MIJ1@213118|Desulfobacterales	28221|Deltaproteobacteria	KO	TIGRFAM hydrogenase accessory protein HypB	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
XH1_k127_8574791_9	1304885.AUEY01000029_gene2497	6.725e-27	119.0	COG0375@1|root,COG0375@2|Bacteria,1Q8XY@1224|Proteobacteria,43EVY@68525|delta/epsilon subdivisions,2WTED@28221|Deltaproteobacteria,2MP81@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	-	-	-	-	-	-	-	-	-	HypA
XH1_k127_8574791_5	933262.AXAM01000064_gene588	1.95e-75	260.0	COG1418@1|root,COG1418@2|Bacteria,1RB2W@1224|Proteobacteria,42RBY@68525|delta/epsilon subdivisions,2WN17@28221|Deltaproteobacteria,2MJPD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
XH1_k127_8574791_3	96561.Dole_1401	1.041e-142	463.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2MIZT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
XH1_k127_8574791_6	1168034.FH5T_00075	9.097e-71	257.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OMP_b-brl,Toluene_X
XH1_k127_8574791_11	216596.pRL120564	7.018e-06	51.0	COG3831@1|root,COG3831@2|Bacteria,1RIDI@1224|Proteobacteria,2UAG1@28211|Alphaproteobacteria,4BG1D@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Proposed nucleic acid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	WGR
XH1_k127_8574791_0	335543.Sfum_0461	1.686e-287	896.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,43BUE@68525|delta/epsilon subdivisions,2X75I@28221|Deltaproteobacteria,2MQ9C@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Conserved carboxylase domain	oadA	-	2.1.3.1,4.1.1.3,6.4.1.1	ko:K01571,ko:K01960,ko:K03416	ko00020,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00640,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344,R00353,R00930	RC00040,RC00097,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
XH1_k127_8574791_2	1304880.JAGB01000001_gene131	4.352e-152	497.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia	186801|Clostridia	I	acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	yqjD	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
XH1_k127_8574791_7	1192034.CAP_2602	7.628e-60	220.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42PI0@68525|delta/epsilon subdivisions,2WJ79@28221|Deltaproteobacteria,2YUU7@29|Myxococcales	28221|Deltaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
XH1_k127_8574791_10	243231.GSU2319	8.252e-11	67.0	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,42V21@68525|delta/epsilon subdivisions,2WRFF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
XH1_k127_8621984_0	644282.Deba_0128	4.265e-238	746.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,42M9A@68525|delta/epsilon subdivisions,2WJ3Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Penicillin amidase	-	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
XH1_k127_8621984_2	706587.Desti_2281	4.225e-113	376.0	COG1148@1|root,COG1378@1|root,COG1148@2|Bacteria,COG1378@2|Bacteria,1R02W@1224|Proteobacteria,43CQ1@68525|delta/epsilon subdivisions,2X7XA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8621984_4	706587.Desti_0651	1.408e-61	216.0	2EB22@1|root,3352W@2|Bacteria,1NE0W@1224|Proteobacteria,42VEE@68525|delta/epsilon subdivisions,2WRJF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8621984_3	706587.Desti_0650	2.404e-67	235.0	COG1309@1|root,COG1309@2|Bacteria,1RJH4@1224|Proteobacteria,42T42@68525|delta/epsilon subdivisions,2WPEX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
XH1_k127_8621984_6	404589.Anae109_3924	3.222e-27	118.0	COG0735@1|root,COG0735@2|Bacteria,1QI59@1224|Proteobacteria,434TD@68525|delta/epsilon subdivisions,2WZ4D@28221|Deltaproteobacteria,2Z1B0@29|Myxococcales	28221|Deltaproteobacteria	K	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
XH1_k127_8621984_7	648996.Theam_1431	1.025e-05	51.0	COG1918@1|root,COG1918@2|Bacteria,2G5F3@200783|Aquificae	200783|Aquificae	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
XH1_k127_8621984_1	1123376.AUIU01000012_gene1330	9.218e-141	469.0	COG0370@1|root,COG0370@2|Bacteria	2|Bacteria	P	ferrous iron transmembrane transporter activity	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
XH1_k127_8621984_5	999547.KI421500_gene1299	2.714e-32	134.0	COG4635@1|root,COG4635@2|Bacteria	2|Bacteria	CH	menaquinone-dependent protoporphyrinogen oxidase activity	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
XH1_k127_8654261_0	880073.Calab_3019	3.078e-50	190.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
XH1_k127_8654261_1	483219.LILAB_26910	1.316e-37	150.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_871557_26	42256.RradSPS_3022	5.755e-13	71.0	COG0166@1|root,COG0166@2|Bacteria,2HFZ9@201174|Actinobacteria,4CPPV@84995|Rubrobacteria	84995|Rubrobacteria	G	Phosphoglucose isomerase	-	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
XH1_k127_871557_0	1125863.JAFN01000001_gene2980	2.312e-224	704.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42MBP@68525|delta/epsilon subdivisions,2WJAJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
XH1_k127_871557_14	1232410.KI421421_gene3683	1.15e-53	204.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,43U6N@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	ATP-grasp domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
XH1_k127_871557_3	1232410.KI421422_gene1998	2.265e-135	445.0	COG0535@1|root,COG0535@2|Bacteria,1NJ3W@1224|Proteobacteria,42PQJ@68525|delta/epsilon subdivisions,2WKAV@28221|Deltaproteobacteria,43T18@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
XH1_k127_871557_21	1121405.dsmv_3549	3.015e-34	138.0	COG2259@1|root,COG2259@2|Bacteria,1NC5I@1224|Proteobacteria,42V27@68525|delta/epsilon subdivisions,2WS2G@28221|Deltaproteobacteria,2MPU2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	MauE
XH1_k127_871557_23	96561.Dole_2883	2.101e-23	109.0	COG0607@1|root,COG0607@2|Bacteria,1N256@1224|Proteobacteria,42TIJ@68525|delta/epsilon subdivisions,2WQHB@28221|Deltaproteobacteria,2MQ0A@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
XH1_k127_871557_4	1304872.JAGC01000009_gene978	3.142e-134	436.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2WJFH@28221|Deltaproteobacteria,2M8CG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
XH1_k127_871557_22	522772.Dacet_2260	6.445e-24	104.0	COG0526@1|root,COG0526@2|Bacteria,2GG1P@200930|Deferribacteres	200930|Deferribacteres	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
XH1_k127_871557_25	891968.Anamo_2067	2.329e-18	89.0	COG0640@1|root,COG0640@2|Bacteria,3TBJ6@508458|Synergistetes	508458|Synergistetes	K	PFAM regulatory protein ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
XH1_k127_871557_1	909663.KI867150_gene149	4.575e-190	606.0	COG0477@1|root,COG0477@2|Bacteria,1RGPN@1224|Proteobacteria,43BMI@68525|delta/epsilon subdivisions,2X6ZQ@28221|Deltaproteobacteria,2MQAD@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
XH1_k127_871557_7	909663.KI867150_gene63	2.243e-104	351.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,42NIC@68525|delta/epsilon subdivisions,2WKV5@28221|Deltaproteobacteria,2MQDK@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
XH1_k127_871557_16	1121413.JMKT01000009_gene2017	1.979e-49	192.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42ZNH@68525|delta/epsilon subdivisions,2WV22@28221|Deltaproteobacteria,2MG18@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
XH1_k127_871557_10	1121405.dsmv_0211	2.435e-72	251.0	COG1024@1|root,COG1024@2|Bacteria,1RIVB@1224|Proteobacteria,42ZKD@68525|delta/epsilon subdivisions,2WUVX@28221|Deltaproteobacteria,2MNDG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
XH1_k127_871557_18	439235.Dalk_2236	4.51e-43	163.0	2D2K4@1|root,32TD0@2|Bacteria,1MZKF@1224|Proteobacteria,42TFV@68525|delta/epsilon subdivisions,2WQ7B@28221|Deltaproteobacteria,2MKHD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3124
XH1_k127_871557_19	443144.GM21_2287	3.561e-41	165.0	COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,42PQN@68525|delta/epsilon subdivisions,2WKV7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	ET	PFAM Extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
XH1_k127_871557_27	1054217.TALC_00340	7.388e-09	68.0	COG2129@1|root,arCOG01145@2157|Archaea,2XXMZ@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM Metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
XH1_k127_871557_24	1123257.AUFV01000003_gene1207	1.012e-19	99.0	COG3216@1|root,COG3216@2|Bacteria,1NGZP@1224|Proteobacteria,1SH1X@1236|Gammaproteobacteria,1XAT4@135614|Xanthomonadales	135614|Xanthomonadales	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2062
XH1_k127_871557_20	1206720.BAFQ01000247_gene5466	3.693e-35	148.0	COG5621@1|root,COG5621@2|Bacteria,2GNHM@201174|Actinobacteria,4FYA5@85025|Nocardiaceae	201174|Actinobacteria	S	secreted hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CrtC
XH1_k127_871557_15	1123274.KB899418_gene2348	2.611e-53	193.0	COG1636@1|root,COG1636@2|Bacteria,2J8F1@203691|Spirochaetes	203691|Spirochaetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
XH1_k127_871557_8	584708.Apau_0658	9.837e-96	325.0	COG3839@1|root,COG3839@2|Bacteria,3TCJF@508458|Synergistetes	508458|Synergistetes	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran,TOBE
XH1_k127_871557_11	717231.Flexsi_1356	1.122e-70	245.0	COG4662@1|root,COG4662@2|Bacteria	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
XH1_k127_871557_5	891968.Anamo_1660	1.081e-118	387.0	COG2998@1|root,COG2998@2|Bacteria,3TA7W@508458|Synergistetes	508458|Synergistetes	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
XH1_k127_871557_13	56780.SYN_00844	1.924e-57	211.0	COG1910@1|root,COG1910@2|Bacteria,1MVS4@1224|Proteobacteria,42NF7@68525|delta/epsilon subdivisions,2WJA9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,PBP_like
XH1_k127_871557_12	443143.GM18_3921	2.958e-70	244.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,42R7A@68525|delta/epsilon subdivisions,2WN7K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
XH1_k127_871557_9	1408422.JHYF01000008_gene3580	4.647e-88	299.0	COG0655@1|root,COG0655@2|Bacteria,1TSY9@1239|Firmicutes,24DR8@186801|Clostridia,36IMZ@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
XH1_k127_871557_2	177437.HRM2_48680	1.065e-138	449.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2MIMG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein, alpha subunit	-	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
XH1_k127_871557_6	1121405.dsmv_0628	5.014e-110	367.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RMH@68525|delta/epsilon subdivisions,2WNKC@28221|Deltaproteobacteria,2MIZ2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB-3	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
XH1_k127_871557_17	1121405.dsmv_0629	9.289e-45	164.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MIMJ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_8726333_1	518766.Rmar_0317	1.51e-159	514.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,4NDWN@976|Bacteroidetes,1FIWU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
XH1_k127_8726333_0	243231.GSU1433	6.556e-203	646.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,43U0I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
XH1_k127_8726333_2	1121918.ARWE01000001_gene1112	1.026e-131	427.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,43S9X@69541|Desulfuromonadales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
XH1_k127_8726333_3	56780.SYN_01342	2.252e-122	399.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2MQ6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
XH1_k127_8726333_6	1232410.KI421421_gene3541	2.837e-30	125.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,42WGY@68525|delta/epsilon subdivisions,2WS4W@28221|Deltaproteobacteria,43VDK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
XH1_k127_8726333_5	626887.J057_03080	1.061e-52	194.0	COG0500@1|root,COG2226@2|Bacteria,1R7VM@1224|Proteobacteria,1SKGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
XH1_k127_8726333_4	1304885.AUEY01000030_gene2438	4.089e-90	306.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,42QEX@68525|delta/epsilon subdivisions,2WMFU@28221|Deltaproteobacteria,2MIVK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Phosphotransferase enzyme family	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
XH1_k127_8732091_1	880073.Calab_0098	1.887e-28	117.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
XH1_k127_8732091_0	880073.Calab_3204	4.813e-141	471.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
XH1_k127_8734464_0	439235.Dalk_1215	1.2e-257	801.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,42NUH@68525|delta/epsilon subdivisions,2WISE@28221|Deltaproteobacteria,2MI4T@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
XH1_k127_8734464_3	1265505.ATUG01000002_gene2479	3.59e-15	81.0	2ET51@1|root,33KP4@2|Bacteria,1P75R@1224|Proteobacteria,433IV@68525|delta/epsilon subdivisions,2WXXD@28221|Deltaproteobacteria,2MPAR@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8734464_1	439235.Dalk_1217	6.6e-206	649.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
XH1_k127_8734464_2	941449.dsx2_3350	2.966e-147	475.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42PBK@68525|delta/epsilon subdivisions,2WIZX@28221|Deltaproteobacteria,2M99E@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
XH1_k127_8734464_4	1121403.AUCV01000041_gene175	6.466e-07	52.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MI80@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class-III	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
XH1_k127_8755781_2	643648.Slip_0879	1.743e-120	399.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,42KGK@68298|Syntrophomonadaceae	186801|Clostridia	K	Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_9,Sigma54_activat
XH1_k127_8755781_1	56780.SYN_03243	4.366e-135	438.0	COG1693@1|root,COG1693@2|Bacteria,1RAC2@1224|Proteobacteria,42QW9@68525|delta/epsilon subdivisions,2WMZV@28221|Deltaproteobacteria,2MQWZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Ribonuclease R winged-helix domain	-	-	-	ko:K09720	-	-	-	-	ko00000,ko03000	-	-	-	DUF128,HTH_12
XH1_k127_8755781_0	264732.Moth_1179	1.244e-293	908.0	COG1304@1|root,COG1304@2|Bacteria,1TPC5@1239|Firmicutes,247PK@186801|Clostridia,42F3T@68295|Thermoanaerobacterales	186801|Clostridia	C	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
XH1_k127_8821958_0	933262.AXAM01000016_gene188	6.839e-181	582.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MIKM@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
XH1_k127_8821958_4	933262.AXAM01000016_gene189	1.536e-92	309.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2MIHA@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
XH1_k127_8821958_2	933262.AXAM01000016_gene190	1.318e-116	383.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2MI4N@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_8821958_1	880073.Calab_3175	2.925e-153	490.0	COG1064@1|root,COG1064@2|Bacteria,2NP06@2323|unclassified Bacteria	2|Bacteria	S	Alcohol dehydrogenase GroES-like domain	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
XH1_k127_8821958_10	56780.SYN_00467	1.188e-14	81.0	COG1633@1|root,COG1633@2|Bacteria,1NG4N@1224|Proteobacteria,42W3T@68525|delta/epsilon subdivisions,2WREZ@28221|Deltaproteobacteria,2MRRS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_8821958_6	207559.Dde_1381	4.242e-67	236.0	COG1018@1|root,COG1018@2|Bacteria,1QUM3@1224|Proteobacteria,431YR@68525|delta/epsilon subdivisions,2WSCB@28221|Deltaproteobacteria,2MCTS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	oxidoreductase FAD NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Ferric_reduct,NAD_binding_1
XH1_k127_8821958_7	398767.Glov_0597	7.506e-45	168.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42SQK@68525|delta/epsilon subdivisions,2WPK1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Protein-tyrosine phosphatase, low molecular weight	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
XH1_k127_8821958_3	444158.MmarC6_1647	1.249e-113	371.0	COG0708@1|root,arCOG02207@2157|Archaea,2XVJ5@28890|Euryarchaeota,23QN3@183939|Methanococci	183939|Methanococci	L	PFAM Endonuclease exonuclease phosphatase	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
XH1_k127_8821958_9	1265505.ATUG01000001_gene2981	2.816e-23	105.0	COG4496@1|root,COG4496@2|Bacteria,1N572@1224|Proteobacteria,42TT6@68525|delta/epsilon subdivisions,2WQN8@28221|Deltaproteobacteria,2MKNX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Trp repressor protein	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
XH1_k127_8821958_5	439235.Dalk_3108	2.456e-69	243.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,43BDR@68525|delta/epsilon subdivisions,2X6SB@28221|Deltaproteobacteria,2MPIC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
XH1_k127_8821958_8	96561.Dole_3272	5.538e-44	170.0	COG0784@1|root,COG2202@1|root,COG3437@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MI5F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
XH1_k127_904988_0	880072.Desac_2923	1.678e-90	308.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2MQ48@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
XH1_k127_904988_2	2754.EH55_12540	1.78e-58	213.0	COG0619@1|root,COG0619@2|Bacteria,3T9YX@508458|Synergistetes	508458|Synergistetes	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
XH1_k127_904988_3	439235.Dalk_2680	2.726e-47	174.0	COG2197@1|root,COG2197@2|Bacteria,1NZMY@1224|Proteobacteria,430BP@68525|delta/epsilon subdivisions,2WVUJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
XH1_k127_904988_4	452471.Aasi_0854	5.28e-46	176.0	COG0790@1|root,COG0790@2|Bacteria,4NMCC@976|Bacteroidetes,47QS2@768503|Cytophagia	976|Bacteroidetes	KLT	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Pkinase,Sel1,Tox-ODYAM1,U-box
XH1_k127_904988_1	1121405.dsmv_0908	3.099e-67	237.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1RCZ1@1224|Proteobacteria,42SIR@68525|delta/epsilon subdivisions,2WPJY@28221|Deltaproteobacteria,2MKCD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
XH1_k127_911195_0	1121405.dsmv_0551	1.749e-117	396.0	COG2911@1|root,COG2911@2|Bacteria,1PQTA@1224|Proteobacteria,42PYT@68525|delta/epsilon subdivisions,2WIZ6@28221|Deltaproteobacteria,2MJ1Q@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
XH1_k127_911195_1	1304885.AUEY01000022_gene3381	3.276e-83	300.0	COG4775@1|root,COG4775@2|Bacteria,1R75N@1224|Proteobacteria,42MIG@68525|delta/epsilon subdivisions,2WMI0@28221|Deltaproteobacteria,2MIJA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
XH1_k127_973685_0	1125863.JAFN01000001_gene835	2.893e-149	492.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
## 2607 queries scanned
## Total time (seconds): 24.018660068511963
## Rate: 108.54 q/s