## Wed Nov 13 06:13:58 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/WX/XH1_bin.8.fa -m mmseqs --itype genome -o XH1_bin.8 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/XH1_bin.8 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
XH1_k127_104007_2	1379698.RBG1_1C00001G0370	1.838e-81	289.0	COG0616@1|root,COG0616@2|Bacteria,2NNKU@2323|unclassified Bacteria	2|Bacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
XH1_k127_104007_0	1121396.KB893069_gene1406	5.225e-215	694.0	COG0280@1|root,COG3426@1|root,COG0280@2|Bacteria,COG3426@2|Bacteria,1QTXP@1224|Proteobacteria,42RGR@68525|delta/epsilon subdivisions,2WNWC@28221|Deltaproteobacteria,2MKSE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acetokinase family	-	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase,Cupin_2,PTA_PTB
XH1_k127_104007_3	243231.GSU1222	1.131e-77	276.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,43TQX@69541|Desulfuromonadales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
XH1_k127_104007_1	1125863.JAFN01000001_gene2044	2.209e-209	672.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
XH1_k127_104007_4	1123386.AUIW01000002_gene1312	1.447e-24	107.0	COG0477@1|root,COG0477@2|Bacteria,1WNEQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
XH1_k127_1048398_4	1168059.KB899087_gene2885	6.315e-12	79.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,3F0V6@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Asparagine synthase	asnO	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
XH1_k127_1048398_0	1191523.MROS_1440	1.48e-228	726.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
XH1_k127_1048398_1	292459.STH885	2.265e-24	121.0	COG0500@1|root,COG2226@2|Bacteria,1TR7I@1239|Firmicutes,24FG4@186801|Clostridia	186801|Clostridia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
XH1_k127_1048398_3	1123072.AUDH01000009_gene470	7.074e-13	81.0	COG0457@1|root,COG0457@2|Bacteria,1RK4Q@1224|Proteobacteria,2UBBB@28211|Alphaproteobacteria,2JSKY@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_9
XH1_k127_1048398_2	338966.Ppro_0516	4.277e-13	80.0	COG0457@1|root,COG0457@2|Bacteria,1PEPM@1224|Proteobacteria,42Y8V@68525|delta/epsilon subdivisions,2WU79@28221|Deltaproteobacteria,43TE3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8
XH1_k127_1056247_10	1121403.AUCV01000025_gene2272	1.491e-18	86.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2MKCX@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
XH1_k127_1056247_1	1379698.RBG1_1C00001G1568	7.101e-105	350.0	COG0202@1|root,COG0202@2|Bacteria,2NNQQ@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
XH1_k127_1056247_3	335543.Sfum_1581	2.877e-68	243.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria,2MRHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
XH1_k127_1056247_6	1379698.RBG1_1C00001G1570	2.205e-49	179.0	COG0100@1|root,COG0100@2|Bacteria,2NPCN@2323|unclassified Bacteria	2|Bacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
XH1_k127_1056247_8	477974.Daud_0250	6.005e-40	153.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,261QX@186807|Peptococcaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
XH1_k127_1056247_11	694431.DESACE_01960	6.382e-12	71.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria,2M7HN@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
XH1_k127_1056247_9	1232437.KL662001_gene4551	2.777e-28	126.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MKKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
XH1_k127_1056247_2	1120973.AQXL01000112_gene1094	3.813e-91	307.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,277XD@186823|Alicyclobacillaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
XH1_k127_1056247_4	387631.Asulf_00712	1.876e-63	224.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
XH1_k127_1056247_0	1379698.RBG1_1C00001G1576	5.816e-173	552.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
XH1_k127_1056247_7	335543.Sfum_1574	1.425e-45	169.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2WQQ4@28221|Deltaproteobacteria,2MQJN@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
XH1_k127_1056247_12	1121364.ATVG01000003_gene1550	7.615e-07	54.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,22P8I@1653|Corynebacteriaceae	201174|Actinobacteria	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
XH1_k127_1056247_5	1519464.HY22_03290	1.846e-57	206.0	COG0098@1|root,COG0098@2|Bacteria,1FD8S@1090|Chlorobi	1090|Chlorobi	J	With S4 and S12 plays an important role in translational accuracy	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
XH1_k127_1077981_1	1444309.JAQG01000008_gene1700	7.812e-79	270.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,26QK6@186822|Paenibacillaceae	91061|Bacilli	IQ	reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
XH1_k127_1077981_5	1234364.AMSF01000037_gene115	3.337e-27	112.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1X7EF@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
XH1_k127_1077981_0	1089548.KI783301_gene2138	1.815e-153	495.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,3WF7V@539002|Bacillales incertae sedis	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
XH1_k127_1077981_2	59374.Fisuc_2018	2.844e-40	171.0	COG0571@1|root,COG0571@2|Bacteria	2|Bacteria	J	ribonuclease III activity	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
XH1_k127_1077981_6	1191523.MROS_2052	4.156e-24	118.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
XH1_k127_1077981_4	215803.DB30_0794	3.454e-31	141.0	COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2YXRH@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
XH1_k127_1077981_3	518766.Rmar_2628	3.274e-40	158.0	COG1595@1|root,COG1595@2|Bacteria,4NQE0@976|Bacteroidetes,1FISP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_1079505_10	278963.ATWD01000001_gene2028	4.839e-06	50.0	COG1884@1|root,COG1884@2|Bacteria,3Y2QA@57723|Acidobacteria,2JKR7@204432|Acidobacteriia	204432|Acidobacteriia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
XH1_k127_1079505_8	1120971.AUCA01000019_gene1128	1.313e-34	139.0	COG0346@1|root,COG2185@1|root,COG0346@2|Bacteria,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,4IRRS@91061|Bacilli,2794J@186823|Alicyclobacillaceae	91061|Bacilli	EI	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,Glyoxalase_4
XH1_k127_1079505_2	1047013.AQSP01000110_gene67	1.026e-131	431.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
XH1_k127_1079505_3	1121472.AQWN01000003_gene1537	7.98e-116	381.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,260DQ@186807|Peptococcaceae	186801|Clostridia	I	PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
XH1_k127_1079505_1	1379698.RBG1_1C00001G1459	3.722e-141	458.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
XH1_k127_1079505_6	1379270.AUXF01000006_gene183	1.003e-57	203.0	COG2185@1|root,COG2185@2|Bacteria,1ZTNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
XH1_k127_1079505_0	760568.Desku_1207	2.424e-249	784.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,260X7@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM methylmalonyl-CoA mutase N-terminal domain	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
XH1_k127_1079505_4	945713.IALB_2003	5.169e-79	274.0	COG1703@1|root,COG1703@2|Bacteria	2|Bacteria	E	isobutyryl-CoA mutase activity	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
XH1_k127_1079505_7	580340.Tlie_1075	6.237e-52	190.0	COG2109@1|root,COG2109@2|Bacteria,3TB75@508458|Synergistetes	508458|Synergistetes	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
XH1_k127_1079505_5	237368.SCABRO_01415	2.457e-69	256.0	COG0642@1|root,COG2205@2|Bacteria,2J4XW@203682|Planctomycetes	203682|Planctomycetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
XH1_k127_1079505_12	765420.OSCT_0445	4.53e-05	55.0	COG3468@1|root,COG3468@2|Bacteria,2GBN5@200795|Chloroflexi,37785@32061|Chloroflexia	32061|Chloroflexia	MU	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
XH1_k127_1079505_9	880073.Calab_1183	2.089e-22	111.0	COG1595@1|root,COG1595@2|Bacteria,2NPRC@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_1079505_11	56780.SYN_02038	4.26e-05	55.0	COG3170@1|root,COG3170@2|Bacteria,1NHGQ@1224|Proteobacteria,42X64@68525|delta/epsilon subdivisions,2WSMQ@28221|Deltaproteobacteria,2MQPS@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF2275,zf-HC2
XH1_k127_1096400_0	880526.KE386488_gene786	3.056e-158	513.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FMUE@200643|Bacteroidia,22V00@171550|Rikenellaceae	976|Bacteroidetes	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
XH1_k127_1096400_1	929556.Solca_2759	3.556e-60	215.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQ80@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
XH1_k127_1142182_1	1267533.KB906733_gene2888	1.82e-10	67.0	COG0457@1|root,COG0457@2|Bacteria,3Y3EM@57723|Acidobacteria,2JIDA@204432|Acidobacteriia	204432|Acidobacteriia	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_11,TPR_16,TPR_2,TPR_8
XH1_k127_1142182_0	1121335.Clst_2501	2.853e-55	216.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia	186801|Clostridia	G	abc transporter atp-binding protein	ecfA	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
XH1_k127_1144195_7	319225.Plut_0105	1.46e-22	103.0	COG2193@1|root,COG2193@2|Bacteria	2|Bacteria	P	ferroxidase activity	bfr	GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
XH1_k127_1144195_6	1047013.AQSP01000110_gene68	2.993e-34	140.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C
XH1_k127_1144195_1	204669.Acid345_4043	2.434e-105	358.0	COG1680@1|root,COG1680@2|Bacteria,3Y7SG@57723|Acidobacteria,2JMWV@204432|Acidobacteriia	204432|Acidobacteriia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
XH1_k127_1144195_3	530564.Psta_3944	2.279e-90	311.0	COG1858@1|root,COG1858@2|Bacteria,2IY7G@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
XH1_k127_1144195_5	330214.NIDE3793	2.106e-38	160.0	29W26@1|root,30HKR@2|Bacteria,3J1BV@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1144195_2	646529.Desaci_1174	5.182e-95	321.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,261PP@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM glycyl-radical enzyme activating protein family	csdA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
XH1_k127_1144195_0	1121422.AUMW01000009_gene3340	0.0	1186.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,2618A@186807|Peptococcaceae	186801|Clostridia	C	Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
XH1_k127_1144195_4	1379270.AUXF01000001_gene2437	1.027e-52	192.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1ZUTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
XH1_k127_1144767_0	562970.Btus_0661	9.095e-284	898.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,2783N@186823|Alicyclobacillaceae	91061|Bacilli	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
XH1_k127_1144767_15	945713.IALB_1647	2.63e-31	143.0	28KE7@1|root,2ZA0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1144767_3	452637.Oter_1254	3.454e-152	497.0	COG0519@1|root,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	2|Bacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
XH1_k127_1144767_1	504472.Slin_6324	3.326e-195	642.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
XH1_k127_1144767_6	945713.IALB_2783	4.938e-112	380.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1144767_4	1121405.dsmv_1218	7.093e-127	407.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,42MR4@68525|delta/epsilon subdivisions,2WM3M@28221|Deltaproteobacteria,2MMW9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
XH1_k127_1144767_12	665571.STHERM_c17870	1.21e-37	160.0	COG1968@1|root,COG1968@2|Bacteria,2J5SC@203691|Spirochaetes	203691|Spirochaetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
XH1_k127_1144767_16	547559.Nmag_3192	4.159e-27	126.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,23SVZ@183963|Halobacteria	183963|Halobacteria	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	ubiA2	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
XH1_k127_1144767_23	545695.TREAZ_0692	3.451e-08	67.0	2C3NG@1|root,348TB@2|Bacteria,2J5WS@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
XH1_k127_1144767_13	1041930.Mtc_1015	5.53e-37	154.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03042@2157|Archaea,2Y7M7@28890|Euryarchaeota,2NBM0@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
XH1_k127_1144767_14	316067.Geob_1006	1.066e-32	139.0	COG0784@1|root,COG0784@2|Bacteria,1N017@1224|Proteobacteria,42UW8@68525|delta/epsilon subdivisions,2X7PA@28221|Deltaproteobacteria,43W1W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
XH1_k127_1144767_10	1121920.AUAU01000011_gene178	7.856e-67	243.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
XH1_k127_1144767_18	748449.Halha_2415	1.247e-21	105.0	COG1560@1|root,COG1560@2|Bacteria,1TT7A@1239|Firmicutes,24HMK@186801|Clostridia,3WANH@53433|Halanaerobiales	186801|Clostridia	M	PFAM Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
XH1_k127_1144767_8	1128421.JAGA01000002_gene120	9.813e-79	289.0	COG0438@1|root,COG0558@1|root,COG0438@2|Bacteria,COG0558@2|Bacteria,2NPRA@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	-	2.4.1.345,2.7.8.5	ko:K00995,ko:K08256	ko00564,ko01100,map00564,map01100	-	R01801,R11702	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000,ko01003	-	GT4	-	CDP-OH_P_transf,Glyco_transf_4,Glycos_transf_1
XH1_k127_1144767_17	1122138.AQUZ01000026_gene2975	6e-26	121.0	COG0477@1|root,COG2814@2|Bacteria,2GM0Q@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
XH1_k127_1144767_20	1499967.BAYZ01000074_gene2082	2.458e-19	98.0	COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	2.7.11.1,2.7.7.65	ko:K02488,ko:K04757	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	HATPase_c,HATPase_c_2,HisKA,Response_reg
XH1_k127_1144767_22	861299.J421_3210	1.998e-14	80.0	2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
XH1_k127_1144767_24	338966.Ppro_0024	3.189e-07	59.0	2AKQ6@1|root,2ZAYQ@2|Bacteria,1R429@1224|Proteobacteria,42NWN@68525|delta/epsilon subdivisions,2WMKI@28221|Deltaproteobacteria,43V14@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM MJ0042 family finger-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
XH1_k127_1144767_11	373903.Hore_15740	2.421e-54	204.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,3WANC@53433|Halanaerobiales	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
XH1_k127_1144767_2	292459.STH1384	4.621e-161	531.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
XH1_k127_1144767_21	1157490.EL26_18140	1.755e-17	83.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4I3V5@91061|Bacilli,278KK@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
XH1_k127_1144767_9	1121439.dsat_2487	9.939e-71	262.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2M7W0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
XH1_k127_1144767_19	756067.MicvaDRAFT_2430	3.412e-21	108.0	COG0457@1|root,COG1215@1|root,COG1216@1|root,COG0457@2|Bacteria,COG1215@2|Bacteria,COG1216@2|Bacteria,1GQBE@1117|Cyanobacteria,1H7DT@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,RgpF,TPR_1,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
XH1_k127_1144767_5	502025.Hoch_5214	9.875e-117	389.0	COG0206@1|root,COG3170@1|root,COG0206@2|Bacteria,COG3170@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2YTTW@29|Myxococcales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
XH1_k127_1144767_7	525897.Dbac_2603	3.478e-104	352.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2M85X@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
XH1_k127_1144767_25	1267533.KB906733_gene3386	8.224e-07	59.0	COG1589@1|root,COG1589@2|Bacteria,3Y3BQ@57723|Acidobacteria,2JIZS@204432|Acidobacteriia	204432|Acidobacteriia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
XH1_k127_1153665_8	338966.Ppro_1358	8.791e-07	62.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,43CDT@68525|delta/epsilon subdivisions,2X7PR@28221|Deltaproteobacteria,43TP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	TonB-dependent Receptor Plug Domain	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
XH1_k127_1153665_0	639282.DEFDS_1109	1.058e-196	628.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
XH1_k127_1153665_2	379066.GAU_2569	2.059e-144	466.0	COG2805@1|root,COG2805@2|Bacteria,1ZSQE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
XH1_k127_1153665_3	1379698.RBG1_1C00001G1741	1.806e-133	436.0	COG1459@1|root,COG1459@2|Bacteria,2NP2J@2323|unclassified Bacteria	2|Bacteria	U	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
XH1_k127_1153665_4	330214.NIDE0778	2.186e-70	259.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
XH1_k127_1153665_1	1379698.RBG1_1C00001G1210	2.107e-148	482.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_1153665_6	1121405.dsmv_2762	7.775e-11	68.0	COG4968@1|root,COG4968@2|Bacteria,1QNMD@1224|Proteobacteria,43A72@68525|delta/epsilon subdivisions,2WYJP@28221|Deltaproteobacteria,2MNPY@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
XH1_k127_1153665_7	243231.GSU1776	2.292e-08	62.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,42ZXF@68525|delta/epsilon subdivisions,2WV6V@28221|Deltaproteobacteria,43UYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Pfam:N_methyl_2	oxpG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
XH1_k127_1153665_5	1192034.CAP_9007	3.952e-29	122.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YUS3@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter, ATP-binding protein	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_1162803_1	580340.Tlie_1593	3.491e-94	314.0	COG1217@1|root,COG1217@2|Bacteria,3T9TF@508458|Synergistetes	508458|Synergistetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
XH1_k127_1162803_0	1379698.RBG1_1C00001G1080	9.018e-150	497.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
XH1_k127_1164577_1	429009.Adeg_0423	1.407e-67	237.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
XH1_k127_1164577_2	706587.Desti_4733	1.22e-60	215.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2MRQU@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
XH1_k127_1164577_0	1121428.DESHY_40229___1	4.495e-103	343.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,2608D@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
XH1_k127_1164577_3	1120985.AUMI01000016_gene1879	9.045e-23	109.0	2FEBN@1|root,346BD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1174439_3	459349.CLOAM1790	6.411e-27	113.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
XH1_k127_1174439_9	880073.Calab_0039	8.099e-07	62.0	COG0308@1|root,COG0308@2|Bacteria,2NRIZ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Cofac_haem_bdg,NAAA-beta,Peptidase_M1,Phospholip_B
XH1_k127_1174439_8	945713.IALB_0487	8.672e-08	64.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	ebh	-	-	-	-	-	-	-	-	-	-	-	DUF1611,Inhibitor_I9,Peptidase_S8,SLH
XH1_k127_1174439_1	237368.SCABRO_02624	7.304e-84	290.0	2BYY4@1|root,2Z80Y@2|Bacteria,2J1QM@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4438)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4438
XH1_k127_1174439_2	880073.Calab_1990	3.316e-81	297.0	COG1404@1|root,COG1404@2|Bacteria,2NNSK@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
XH1_k127_1174439_0	909663.KI867149_gene3375	0.0	1283.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MQB6@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
XH1_k127_1174439_5	1121403.AUCV01000005_gene233	5.547e-18	91.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria,2MHV1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
XH1_k127_1174439_7	941824.TCEL_01381	3.432e-10	73.0	COG0296@1|root,COG0366@1|root,COG0296@2|Bacteria,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,36EQD@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_N,Big_2,CBM_20,CBM_48,Cadherin-like,Malt_amylase_C,PUD,SLH
XH1_k127_1174439_6	941824.TCEL_01381	6.437e-13	79.0	COG0296@1|root,COG0366@1|root,COG0296@2|Bacteria,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,36EQD@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_N,Big_2,CBM_20,CBM_48,Cadherin-like,Malt_amylase_C,PUD,SLH
XH1_k127_1174439_4	379066.GAU_2631	9.142e-19	90.0	COG0296@1|root,COG0296@2|Bacteria,1ZUYU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1174439_11	1227499.C493_09383	0.0009216	52.0	2DZ85@1|root,2N5HN@2157|Archaea,2Y0TM@28890|Euryarchaeota,23Y9H@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
XH1_k127_1187884_0	1304875.JAFZ01000001_gene1136	2.371e-176	562.0	COG1217@1|root,COG1217@2|Bacteria,3T9TF@508458|Synergistetes	508458|Synergistetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
XH1_k127_1187884_3	870187.Thini_0382	6.184e-32	129.0	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,463F1@72273|Thiotrichales	72273|Thiotrichales	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
XH1_k127_1187884_1	935845.JADQ01000029_gene1230	9.55e-137	459.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
XH1_k127_1187884_4	459349.CLOAM0984	1.165e-17	98.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
XH1_k127_1187884_2	931626.Awo_c14850	1.836e-34	134.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,25VEF@186806|Eubacteriaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
XH1_k127_1194231_14	1047013.AQSP01000111_gene1671	1.286e-06	50.0	2CESB@1|root,2Z8UZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
XH1_k127_1194231_11	1123242.JH636438_gene5778	7.118e-27	124.0	COG1807@1|root,COG1807@2|Bacteria,2IZ75@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_1194231_5	1123277.KB893195_gene5531	1.851e-71	249.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,47UDR@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH1_k127_1194231_10	1123037.AUDE01000018_gene2887	1.544e-28	130.0	COG0265@1|root,COG1572@1|root,COG3291@1|root,COG0265@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,4NIM1@976|Bacteroidetes,1I0WD@117743|Flavobacteriia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_M43,Reprolysin_3
XH1_k127_1194231_2	1121422.AUMW01000024_gene244	1.13e-90	312.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,260HS@186807|Peptococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
XH1_k127_1194231_8	266117.Rxyl_1939	2.209e-47	186.0	COG0438@1|root,COG0438@2|Bacteria,2GN28@201174|Actinobacteria,4CSV6@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
XH1_k127_1194231_12	880073.Calab_0921	2.124e-18	100.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
XH1_k127_1194231_4	1122176.KB903532_gene2680	9.293e-72	249.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1IQFC@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
XH1_k127_1194231_3	1283300.ATXB01000002_gene3013	4.96e-83	299.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1XEUV@135618|Methylococcales	135618|Methylococcales	H	TonB dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
XH1_k127_1194231_13	909663.KI867150_gene1619	1.873e-14	82.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,42W54@68525|delta/epsilon subdivisions,2WR8H@28221|Deltaproteobacteria,2MSEJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
XH1_k127_1194231_7	880072.Desac_2642	2.655e-65	229.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,2MSIW@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
XH1_k127_1194231_1	319225.Plut_1242	2.879e-109	362.0	COG1117@1|root,COG1117@2|Bacteria,1FEDI@1090|Chlorobi	1090|Chlorobi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
XH1_k127_1194231_0	319225.Plut_1243	3.935e-161	518.0	COG0581@1|root,COG0581@2|Bacteria,1FE3G@1090|Chlorobi	1090|Chlorobi	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
XH1_k127_1194231_6	194439.CT0897	5.363e-68	236.0	COG0573@1|root,COG0573@2|Bacteria,1FE1M@1090|Chlorobi	1090|Chlorobi	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstC	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
XH1_k127_1195739_3	1111121.HMPREF1247_0627	9.327e-06	55.0	COG0619@1|root,COG0619@2|Bacteria,2HTTD@201174|Actinobacteria,4CW8M@84998|Coriobacteriia	84998|Coriobacteriia	P	PFAM Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
XH1_k127_1195739_1	215803.DB30_0743	8.49e-37	160.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
XH1_k127_1195739_2	1379698.RBG1_1C00001G0634	3.119e-35	149.0	COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
XH1_k127_1195739_4	449673.BACSTE_02351	0.0004394	53.0	2DKZS@1|root,311B0@2|Bacteria,4NQ1B@976|Bacteroidetes,2FS9G@200643|Bacteroidia,4AVA0@815|Bacteroidaceae	976|Bacteroidetes	S	Fimbrillin-like	-	-	-	-	-	-	-	-	-	-	-	-	Mfa_like_1
XH1_k127_1195739_0	1047013.AQSP01000140_gene2549	8.577e-89	299.0	COG1067@1|root,COG1067@2|Bacteria,2NP29@2323|unclassified Bacteria	2|Bacteria	O	peptidase S16	ycbZ	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
XH1_k127_1201663_4	1110502.TMO_2441	0.0002712	49.0	2DG7Q@1|root,2ZUUI@2|Bacteria,1P8CE@1224|Proteobacteria,2UYU4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function with HXXEE motif	-	-	-	-	-	-	-	-	-	-	-	-	HXXEE
XH1_k127_1201663_1	1254432.SCE1572_02625	2.28e-42	158.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1N3KK@1224|Proteobacteria,42TH7@68525|delta/epsilon subdivisions,2WQ6A@28221|Deltaproteobacteria,2YVVZ@29|Myxococcales	28221|Deltaproteobacteria	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,GIY-YIG,HTH_20
XH1_k127_1201663_0	671143.DAMO_2282	9.323e-53	191.0	COG3189@1|root,COG3189@2|Bacteria	2|Bacteria	K	MarR family transcriptional regulator	yeaO	-	-	-	-	-	-	-	-	-	-	-	DUF488
XH1_k127_1240526_0	1267535.KB906767_gene5241	2.859e-135	444.0	COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
XH1_k127_1240526_1	1047013.AQSP01000067_gene2199	8.935e-79	273.0	COG3379@1|root,COG3379@2|Bacteria,2NQEW@2323|unclassified Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
XH1_k127_1242840_9	861299.J421_2489	6.36e-36	154.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
XH1_k127_1242840_7	768671.ThimaDRAFT_4749	7.971e-56	210.0	COG0438@1|root,COG0438@2|Bacteria,1RCC7@1224|Proteobacteria,1S51S@1236|Gammaproteobacteria,1X1N0@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
XH1_k127_1242840_0	330214.NIDE3016	1.721e-120	391.0	COG1209@1|root,COG1209@2|Bacteria,3J0KX@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
XH1_k127_1242840_6	1501230.ET33_31155	4.968e-61	220.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,26SEN@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
XH1_k127_1242840_5	56780.SYN_00576	4.845e-64	223.0	COG1898@1|root,COG1898@2|Bacteria,1RGRQ@1224|Proteobacteria,42RZA@68525|delta/epsilon subdivisions,2WNBP@28221|Deltaproteobacteria,2MRPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	WxcM-like, C-terminal	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
XH1_k127_1242840_1	247490.KSU1_C1608	1.034e-118	402.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
XH1_k127_1242840_10	247490.KSU1_C1607	4.752e-29	131.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	-	2.1.1.45,2.7.4.9	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02094,R02098,R02101	RC00002,RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
XH1_k127_1242840_8	247490.KSU1_C1606	2.128e-46	181.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	epsD	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754,ko:K19422	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
XH1_k127_1242840_2	234267.Acid_0283	5.213e-118	390.0	COG0399@1|root,COG0399@2|Bacteria,3Y3PT@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
XH1_k127_1242840_4	1519464.HY22_10230	4.514e-68	239.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1FEH6@1090|Chlorobi	1090|Chlorobi	GM	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
XH1_k127_1242840_3	1396141.BATP01000036_gene3854	1.853e-109	364.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia,2IU1W@203494|Verrucomicrobiae	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
XH1_k127_1248466_3	1265505.ATUG01000001_gene4730	0.0002915	49.0	COG0745@1|root,COG0745@2|Bacteria,1RIGT@1224|Proteobacteria,42SWP@68525|delta/epsilon subdivisions,2WPJ3@28221|Deltaproteobacteria,2MKT8@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	CheY-like receiver, AAA-type ATPase and DNA-binding domain-containing response regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
XH1_k127_1248466_1	298654.FraEuI1c_4156	6.816e-09	69.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4EUES@85013|Frankiales	201174|Actinobacteria	T	response regulator	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
XH1_k127_1248466_0	945713.IALB_2290	2.629e-11	70.0	2AQ71@1|root,31FCR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1248466_2	880073.Calab_2082	8.086e-08	64.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
XH1_k127_1269123_3	300852.55771744	4.152e-46	176.0	COG1496@1|root,COG1496@2|Bacteria,1WI9I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the multicopper oxidase YfiH RL5 family	-	GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
XH1_k127_1269123_0	1128421.JAGA01000003_gene2811	3.354e-89	308.0	COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
XH1_k127_1269123_10	1379698.RBG1_1C00001G1235	8.752e-12	78.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
XH1_k127_1269123_6	289376.THEYE_A0959	9.417e-31	130.0	COG0811@1|root,COG0811@2|Bacteria,3J0PX@40117|Nitrospirae	40117|Nitrospirae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
XH1_k127_1269123_7	1379698.RBG1_1C00001G0498	1.127e-22	111.0	COG0848@1|root,COG0848@2|Bacteria,2NPWJ@2323|unclassified Bacteria	2|Bacteria	U	Biopolymer transport protein ExbD/TolR	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
XH1_k127_1269123_8	1047013.AQSP01000135_gene1614	5.827e-15	83.0	COG0810@1|root,COG0810@2|Bacteria,2NQ3G@2323|unclassified Bacteria	2|Bacteria	M	TonB C terminal	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
XH1_k127_1269123_2	443144.GM21_3582	5.326e-67	250.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
XH1_k127_1269123_5	290315.Clim_0748	1.53e-34	143.0	COG2885@1|root,COG2885@2|Bacteria,1FEC5@1090|Chlorobi	1090|Chlorobi	M	PFAM OmpA MotB domain protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
XH1_k127_1269123_11	391593.RCCS2_05529	0.0001791	53.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2U6ZQ@28211|Alphaproteobacteria,2P23R@2433|Roseobacter	28211|Alphaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
XH1_k127_1269123_1	667014.Thein_0904	7.83e-68	247.0	COG1253@1|root,COG1253@2|Bacteria,2GHSF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
XH1_k127_1269123_4	1499967.BAYZ01000088_gene5099	3.016e-35	154.0	COG1253@1|root,COG1253@2|Bacteria,2NP04@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
XH1_k127_1269123_9	1379270.AUXF01000004_gene3060	5.744e-13	72.0	COG3367@1|root,COG3367@2|Bacteria,1ZUM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
XH1_k127_1278406_8	1232410.KI421413_gene692	1.71e-75	267.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
XH1_k127_1278406_4	1120985.AUMI01000019_gene2299	5.74e-111	382.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4H2A2@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
XH1_k127_1278406_5	1121468.AUBR01000030_gene1220	1.579e-99	334.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,42F74@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
XH1_k127_1278406_18	1379698.RBG1_1C00001G1829	4.32e-20	91.0	COG0333@1|root,COG0333@2|Bacteria,2NQ1M@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal L32p protein family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
XH1_k127_1278406_17	1379698.RBG1_1C00001G1830	5.272e-22	102.0	COG1399@1|root,COG1399@2|Bacteria,2NPVD@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1399	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
XH1_k127_1278406_15	929713.NIASO_04635	1.958e-34	137.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1ISC1@117747|Sphingobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
XH1_k127_1278406_3	379066.GAU_1645	9.487e-116	379.0	COG0074@1|root,COG0074@2|Bacteria,1ZT20@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
XH1_k127_1278406_2	861299.J421_3279	1.054e-127	418.0	COG0045@1|root,COG0045@2|Bacteria,1ZSZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
XH1_k127_1278406_1	880073.Calab_0633	6.604e-196	619.0	COG2403@1|root,COG2403@2|Bacteria,2NNTB@2323|unclassified Bacteria	2|Bacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	cpgS	-	-	ko:K05716	-	-	R03298	RC00900	ko00000,ko01000	-	-	-	cobW
XH1_k127_1278406_13	338963.Pcar_1282	4.612e-45	181.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,43TN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
XH1_k127_1278406_9	1379698.RBG1_1C00001G1507	1.583e-74	262.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
XH1_k127_1278406_16	1519464.HY22_09940	5.73e-25	108.0	COG4191@1|root,COG4191@2|Bacteria,1FFJ1@1090|Chlorobi	1090|Chlorobi	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
XH1_k127_1278406_12	1379698.RBG1_1C00001G1514	6.633e-56	208.0	COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria	2|Bacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
XH1_k127_1278406_6	868131.MSWAN_0651	2.381e-96	329.0	COG2006@1|root,arCOG02447@2157|Archaea,2XW1U@28890|Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S ferredoxin iron-sulfur binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_7
XH1_k127_1278406_10	323261.Noc_3012	3.707e-74	264.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1WWKX@135613|Chromatiales	135613|Chromatiales	LU	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
XH1_k127_1278406_14	243231.GSU0224	2.824e-39	149.0	COG1917@1|root,COG1917@2|Bacteria,1RJX2@1224|Proteobacteria,42TVK@68525|delta/epsilon subdivisions,2WQ2T@28221|Deltaproteobacteria,43SQH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
XH1_k127_1278406_0	338966.Ppro_1051	4.523e-288	896.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
XH1_k127_1278406_7	96561.Dole_2121	1.127e-81	284.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria,2MI2C@213118|Desulfobacterales	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
XH1_k127_1278406_11	1123392.AQWL01000003_gene277	1.998e-62	223.0	COG0778@1|root,COG0778@2|Bacteria,1Q0ZY@1224|Proteobacteria,2WAFT@28216|Betaproteobacteria,1KSUE@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
XH1_k127_1282274_1	1123508.JH636439_gene936	1.667e-96	323.0	COG0005@1|root,COG0005@2|Bacteria,2IX9R@203682|Planctomycetes	203682|Planctomycetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
XH1_k127_1282274_0	1121921.KB898707_gene836	4.417e-261	834.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,2PP77@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
XH1_k127_1300074_7	497964.CfE428DRAFT_4728	2.905e-30	128.0	COG0463@1|root,COG0463@2|Bacteria,46UW3@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH1_k127_1300074_8	398767.Glov_2207	4.414e-25	115.0	COG1560@1|root,COG1560@2|Bacteria,1NJIN@1224|Proteobacteria,431MM@68525|delta/epsilon subdivisions,2WX1W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
XH1_k127_1300074_9	1232410.KI421413_gene670	1.795e-20	102.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,42V1F@68525|delta/epsilon subdivisions,2WR79@28221|Deltaproteobacteria,43SR6@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
XH1_k127_1300074_1	1379698.RBG1_1C00001G1178	8.905e-103	354.0	COG0240@1|root,COG0240@2|Bacteria,2NP1N@2323|unclassified Bacteria	2|Bacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
XH1_k127_1300074_6	574087.Acear_1046	3.191e-31	141.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3WAQW@53433|Halanaerobiales	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
XH1_k127_1300074_2	1121472.AQWN01000003_gene1643	4.545e-100	354.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,2602V@186807|Peptococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
XH1_k127_1300074_3	477974.Daud_1173	1.068e-86	302.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,260YG@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,PDZ
XH1_k127_1300074_11	1158318.ATXC01000001_gene948	5.46e-06	48.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_2,TonB_C
XH1_k127_1300074_5	1123371.ATXH01000016_gene1844	5.8e-59	229.0	COG0324@1|root,COG0324@2|Bacteria,2GH70@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
XH1_k127_1300074_0	194439.CT2028	1.472e-113	390.0	COG0323@1|root,COG0323@2|Bacteria,1FDFS@1090|Chlorobi	1090|Chlorobi	J	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
XH1_k127_1300074_10	439235.Dalk_3497	1.959e-07	64.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1QW1M@1224|Proteobacteria	1224|Proteobacteria	T	SMART PAS domain containing protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	-
XH1_k127_1300074_4	479434.Sthe_0669	1.484e-82	281.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia	189775|Thermomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
XH1_k127_1302927_0	479434.Sthe_2092	9.292e-105	367.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.1.11.5,3.1.12.1,3.6.4.12	ko:K01144,ko:K07464,ko:K16898	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
XH1_k127_1341531_0	370438.PTH_0900	8.031e-141	484.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia,2608I@186807|Peptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
XH1_k127_1341531_1	1125863.JAFN01000001_gene208	5.344e-123	414.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2WJJW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_2942	tRNA-synt_2e
XH1_k127_1341531_4	525264.HMPREF0305_12126	5.682e-10	72.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,22K9A@1653|Corynebacteriaceae	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
XH1_k127_1341531_3	926692.AZYG01000007_gene1279	1.027e-41	163.0	COG2928@1|root,COG2928@2|Bacteria,1V6FM@1239|Firmicutes,24JQ1@186801|Clostridia,3WBT4@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
XH1_k127_1341531_2	665571.STHERM_c09770	6.495e-59	220.0	COG1253@1|root,COG1253@2|Bacteria,2J61P@203691|Spirochaetes	203691|Spirochaetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	tlyC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
XH1_k127_1341531_5	545264.KB898755_gene2759	3.327e-08	58.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1WYGP@135613|Chromatiales	135613|Chromatiales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
XH1_k127_1342335_0	1191523.MROS_1041	5.789e-319	994.0	COG0188@1|root,COG0188@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
XH1_k127_1342335_1	1122915.AUGY01000043_gene7881	1.165e-260	817.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,26R74@186822|Paenibacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
XH1_k127_1342335_6	1232410.KI421421_gene3837	8.167e-16	81.0	COG5512@1|root,COG5512@2|Bacteria,1N24G@1224|Proteobacteria,42TXW@68525|delta/epsilon subdivisions,2WQ15@28221|Deltaproteobacteria,43SMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
XH1_k127_1342335_4	1121335.Clst_0003	1.019e-48	189.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3WHXU@541000|Ruminococcaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
XH1_k127_1342335_3	1379270.AUXF01000002_gene1191	6.225e-80	281.0	COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
XH1_k127_1342335_2	370438.PTH_0001	7.308e-138	451.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,260P2@186807|Peptococcaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
XH1_k127_1342335_7	563040.Saut_1670	2.248e-12	69.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,42WSU@68525|delta/epsilon subdivisions,2YQ70@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
XH1_k127_1342335_8	871968.DESME_15905	4.76e-12	72.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,262VE@186807|Peptococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
XH1_k127_1342335_5	402626.Rpic_3758	2.928e-21	98.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,1K9BR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
XH1_k127_1361914_0	269797.Mbar_A2113	2.867e-49	200.0	COG4870@1|root,arCOG03607@2157|Archaea,2XWQ1@28890|Euryarchaeota,2NAG9@224756|Methanomicrobia	224756|Methanomicrobia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	NosD,PKD,Peptidase_C1
XH1_k127_1393973_12	1131462.DCF50_p1468	9.41e-39	149.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,261GH@186807|Peptococcaceae	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
XH1_k127_1393973_5	379066.GAU_1515	1.017e-117	387.0	COG0540@1|root,COG0540@2|Bacteria,1ZSN7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
XH1_k127_1393973_4	767817.Desgi_3054	1.828e-122	406.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
XH1_k127_1393973_11	1379698.RBG1_1C00001G0226	1.869e-39	171.0	COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
XH1_k127_1393973_13	429009.Adeg_0374	3.552e-34	150.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,42GEQ@68295|Thermoanaerobacterales	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
XH1_k127_1393973_7	589865.DaAHT2_2005	3.881e-66	243.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2MIHH@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
XH1_k127_1393973_8	1121468.AUBR01000005_gene8	1.458e-59	229.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,42G12@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
XH1_k127_1393973_6	665956.HMPREF1032_02344	4.235e-91	319.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,2494X@186801|Clostridia,3WIGS@541000|Ruminococcaceae	186801|Clostridia	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
XH1_k127_1393973_1	1122919.KB905549_gene2055	7.388e-131	426.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,4HB2M@91061|Bacilli,26S2Z@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
XH1_k127_1393973_9	1121346.KB899822_gene2902	8.565e-57	222.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,4HF5Y@91061|Bacilli,275YJ@186822|Paenibacillaceae	91061|Bacilli	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
XH1_k127_1393973_0	1123376.AUIU01000004_gene1166	7.531e-157	505.0	COG1004@1|root,COG1004@2|Bacteria,3J0EJ@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
XH1_k127_1393973_2	880073.Calab_3419	1.667e-129	424.0	COG1088@1|root,COG1088@2|Bacteria,2NNRC@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46,4.2.1.76	ko:K01710,ko:K12450	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R00293,R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3464	GDP_Man_Dehyd
XH1_k127_1393973_3	1519464.HY22_12365	2.254e-128	436.0	COG0381@1|root,COG0381@2|Bacteria,1FDZG@1090|Chlorobi	1090|Chlorobi	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
XH1_k127_1393973_10	1265845.PWEIH_00845	8.599e-40	163.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,26JT3@186820|Listeriaceae	91061|Bacilli	M	transferase	tagO	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
XH1_k127_1441489_3	644282.Deba_3266	9.581e-44	169.0	28N2R@1|root,2ZB8J@2|Bacteria,1R9S3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
XH1_k127_1441489_1	1158345.JNLL01000001_gene1457	1.167e-82	290.0	COG2885@1|root,COG2885@2|Bacteria,2G4S4@200783|Aquificae	200783|Aquificae	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_YMGG,OmpA,TSP_3
XH1_k127_1441489_0	56780.SYN_01924	1.947e-130	424.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,42NRA@68525|delta/epsilon subdivisions,2WJ62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
XH1_k127_1441489_5	449673.BACSTE_03846	3.441e-07	56.0	2AHEJ@1|root,317RR@2|Bacteria,4P93N@976|Bacteroidetes,2FZC5@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1441489_2	985867.AEWF01000006_gene496	5.72e-51	181.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,2U8PC@28211|Alphaproteobacteria,47G6G@766|Rickettsiales	766|Rickettsiales	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1441489_4	471874.PROSTU_00109	2.488e-23	101.0	29XIP@1|root,30J9M@2|Bacteria,1QGXJ@1224|Proteobacteria,1TEDR@1236|Gammaproteobacteria,3ZADK@586|Providencia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1456159_12	888060.HMPREF9081_2274	1.324e-06	58.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,4H3ET@909932|Negativicutes	909932|Negativicutes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
XH1_k127_1456159_11	1183438.GKIL_0563	1.468e-07	61.0	COG0810@1|root,COG0810@2|Bacteria,1G6FF@1117|Cyanobacteria	1117|Cyanobacteria	M	TIGRFAM TonB family C-terminal domain	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
XH1_k127_1456159_8	96561.Dole_1763	1.207e-18	98.0	COG0683@1|root,COG1729@1|root,COG0683@2|Bacteria,COG1729@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria,2MHTC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC,Peripla_BP_6,TPR_16,TPR_6
XH1_k127_1456159_2	335543.Sfum_1929	3.144e-53	192.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2WP23@28221|Deltaproteobacteria,2MS26@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
XH1_k127_1456159_5	96561.Dole_2354	1.493e-31	130.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2MJT1@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
XH1_k127_1456159_10	1122179.KB890420_gene2490	1.541e-11	76.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,YfiO
XH1_k127_1456159_9	596330.HMPREF0628_1031	2.899e-13	82.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,22H08@1570339|Peptoniphilaceae	186801|Clostridia	M	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
XH1_k127_1456159_1	56780.SYN_01031	5.769e-84	290.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2MQDR@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Nucleotidyl transferase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
XH1_k127_1456159_0	596152.DesU5LDRAFT_1064	5.266e-148	481.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2M9RV@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
XH1_k127_1456159_3	880073.Calab_2408	5.547e-41	155.0	COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria	2|Bacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
XH1_k127_1456159_7	545695.TREAZ_0630	3.809e-20	92.0	COG0238@1|root,COG0238@2|Bacteria,2J8ZY@203691|Spirochaetes	203691|Spirochaetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
XH1_k127_1456159_6	536232.CLM_4133	7.818e-22	99.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,36JK5@31979|Clostridiaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
XH1_k127_1456159_4	521674.Plim_2628	2.647e-33	134.0	COG0193@1|root,COG0193@2|Bacteria,2IZXT@203682|Planctomycetes	203682|Planctomycetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
XH1_k127_1457561_0	748658.KB907314_gene236	6.271e-122	415.0	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,1RQ9P@1236|Gammaproteobacteria,1X2BJ@135613|Chromatiales	135613|Chromatiales	M	Cellulose synthase	-	-	-	-	-	-	-	-	-	-	-	-	Cellulose_synt,Glycos_transf_2,PilZ
XH1_k127_1457561_1	232721.Ajs_3182	0.0006531	44.0	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,2VQPH@28216|Betaproteobacteria,4ADNJ@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
XH1_k127_1460767_2	1395513.P343_01110	3.214e-15	79.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,26P0C@186821|Sporolactobacillaceae	91061|Bacilli	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
XH1_k127_1460767_0	933262.AXAM01000030_gene807	7.556e-61	223.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2MI3R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
XH1_k127_1460767_1	246194.CHY_1281	1.213e-29	123.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,42FCT@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM PP-loop domain protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
XH1_k127_151181_6	1499967.BAYZ01000068_gene1963	1.658e-13	79.0	COG3307@1|root,COG3307@2|Bacteria,2NQ25@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
XH1_k127_151181_2	1499967.BAYZ01000193_gene3921	3.655e-70	249.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
XH1_k127_151181_0	1379698.RBG1_1C00001G1326	1.737e-152	489.0	COG2006@1|root,COG2006@2|Bacteria,2NPTK@2323|unclassified Bacteria	2|Bacteria	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
XH1_k127_151181_3	643648.Slip_0101	1.41e-46	184.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,42JVK@68298|Syntrophomonadaceae	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
XH1_k127_151181_5	1379698.RBG1_1C00001G0639	1.589e-24	105.0	COG2088@1|root,COG2088@2|Bacteria,2NQ05@2323|unclassified Bacteria	2|Bacteria	D	SpoVG	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
XH1_k127_151181_1	330214.NIDE0781	8.006e-109	361.0	COG0462@1|root,COG0462@2|Bacteria,3J0D0@40117|Nitrospirae	40117|Nitrospirae	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
XH1_k127_151181_4	497964.CfE428DRAFT_1544	2.076e-37	154.0	COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
XH1_k127_151181_7	554065.XP_005843082.1	1.681e-09	59.0	COG0193@1|root,KOG2255@2759|Eukaryota	2759|Eukaryota	J	aminoacyl-tRNA hydrolase activity	-	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0016787,GO:0016788,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056,ko:K12900	ko03040,map03040	-	-	-	ko00000,ko00001,ko01000,ko01009,ko03012,ko03041	-	-	-	Pept_tRNA_hydro
XH1_k127_1538397_3	330214.NIDE4143	1.214e-29	130.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Spermine_synth
XH1_k127_1538397_4	693661.Arcve_1432	5.175e-09	60.0	arCOG13418@1|root,arCOG13418@2157|Archaea,2Y5VK@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1538397_1	1382359.JIAL01000001_gene2266	2.019e-34	147.0	COG0265@1|root,COG0265@2|Bacteria,3Y7GN@57723|Acidobacteria,2JM8V@204432|Acidobacteriia	204432|Acidobacteriia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1538397_2	459349.CLOAM1614	4.653e-30	138.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,2NR5X@2323|unclassified Bacteria	2|Bacteria	Q	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,FlgD_ig,Laminin_G_3
XH1_k127_1538397_0	448385.sce3387	7.312e-46	189.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1556334_1	1379698.RBG1_1C00001G0356	2.091e-09	60.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
XH1_k127_1556334_0	880073.Calab_1385	1.098e-40	165.0	COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT,PMT_2,TPR_19
XH1_k127_1595778_4	518766.Rmar_2723	1.099e-33	145.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes	976|Bacteroidetes	S	TIGRFAM N-terminal double-transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA
XH1_k127_1595778_2	1379698.RBG1_1C00001G0202	7.476e-96	323.0	COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
XH1_k127_1595778_1	1379698.RBG1_1C00001G0201	5.073e-125	410.0	COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria	2|Bacteria	O	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
XH1_k127_1595778_3	886293.Sinac_3436	4.979e-75	260.0	COG3228@1|root,COG3228@2|Bacteria,2IZES@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90,SEC-C
XH1_k127_1595778_7	660470.Theba_2352	1.481e-05	59.0	COG3209@1|root,COG4870@1|root,COG3209@2|Bacteria,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
XH1_k127_1595778_6	459349.CLOAM0604	3.369e-28	133.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1595778_0	96561.Dole_0811	6.227e-131	428.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria,2MJ98@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
XH1_k127_1595778_5	96561.Dole_0810	1.437e-33	132.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria,2MJ2Q@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
XH1_k127_1623669_4	1379698.RBG1_1C00001G1024	2.73e-21	109.0	COG0382@1|root,COG0382@2|Bacteria,2NRJ9@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	-	-	2.5.1.133,2.5.1.39,2.5.1.62	ko:K03179,ko:K04040	ko00130,ko00860,ko01100,ko01110,map00130,map00860,map01100,map01110	M00117	R05000,R05615,R06284,R09067,R11514,R11517	RC00020,RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
XH1_k127_1623669_0	1123371.ATXH01000040_gene1169	2.968e-119	404.0	COG1022@1|root,COG1022@2|Bacteria,2GIQW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
XH1_k127_1623669_1	370438.PTH_0928	9.739e-104	345.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,2613G@186807|Peptococcaceae	186801|Clostridia	C	radical SAM domain protein	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
XH1_k127_1623669_3	264732.Moth_1212	1.536e-47	184.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,42J1R@68295|Thermoanaerobacterales	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
XH1_k127_1623669_2	716544.wcw_1745	5.603e-53	193.0	COG0566@1|root,COG0566@2|Bacteria,2JFQK@204428|Chlamydiae	204428|Chlamydiae	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU_1	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
XH1_k127_1626436_0	180332.JTGN01000002_gene5672	9.505e-19	92.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia	186801|Clostridia	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
XH1_k127_1626436_1	1392488.JHZY01000004_gene3566	0.0001469	55.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1HZ3R@117743|Flavobacteriia,2XIVE@283735|Leeuwenhoekiella	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1638706_3	289376.THEYE_A0958	7.448e-13	77.0	COG0848@1|root,COG0848@2|Bacteria,3J0T6@40117|Nitrospirae	40117|Nitrospirae	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
XH1_k127_1638706_7	69279.BG36_19515	4.623e-05	53.0	COG0848@1|root,COG0848@2|Bacteria,1RDJZ@1224|Proteobacteria,2U77T@28211|Alphaproteobacteria,43K19@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	TonB system transport protein ExbD	exbD	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
XH1_k127_1638706_2	1045858.Bint_1622	2.597e-21	103.0	COG0811@1|root,COG0811@2|Bacteria,2J700@203691|Spirochaetes	203691|Spirochaetes	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
XH1_k127_1638706_5	314230.DSM3645_25332	2.191e-07	65.0	COG1729@1|root,COG3071@1|root,COG1729@2|Bacteria,COG3071@2|Bacteria,2IZUV@203682|Planctomycetes	203682|Planctomycetes	H	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
XH1_k127_1638706_8	1123399.AQVE01000012_gene2927	0.0004901	54.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,460ZY@72273|Thiotrichales	72273|Thiotrichales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
XH1_k127_1638706_6	1480694.DC28_01735	3.411e-05	56.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
XH1_k127_1638706_4	880073.Calab_2182	1.078e-10	74.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
XH1_k127_1638706_1	1297865.APJD01000003_gene6130	3.928e-46	192.0	COG1572@1|root,COG2755@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG1572@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3JWUW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	QU	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,HemolysinCabind
XH1_k127_1638706_0	237368.SCABRO_02223	2.08e-144	464.0	COG0714@1|root,COG0714@2|Bacteria,2IX23@203682|Planctomycetes	203682|Planctomycetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
XH1_k127_169534_4	679937.Bcop_1887	4.617e-06	50.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,2FTD1@200643|Bacteroidia,4ARAM@815|Bacteroidaceae	976|Bacteroidetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
XH1_k127_169534_3	1184267.A11Q_2181	1.713e-26	115.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2MU5K@213481|Bdellovibrionales,2WT56@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
XH1_k127_169534_1	525904.Tter_2605	7.158e-52	203.0	COG1472@1|root,COG1472@2|Bacteria,2NNZB@2323|unclassified Bacteria	2|Bacteria	G	Glycoside hydrolase family 3 domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
XH1_k127_169534_0	1379698.RBG1_1C00001G0322	2.081e-55	211.0	COG2385@1|root,COG2385@2|Bacteria,2NPRR@2323|unclassified Bacteria	2|Bacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
XH1_k127_169534_2	880073.Calab_1286	5.237e-29	137.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
XH1_k127_1717587_4	1358423.N180_07620	2.333e-11	70.0	2E2JB@1|root,32XNT@2|Bacteria,4NT2W@976|Bacteroidetes,1IU7J@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_1717587_3	1233950.IW22_01920	9.674e-15	88.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NJ5G@976|Bacteroidetes,1HX8E@117743|Flavobacteriia,3ZRBS@59732|Chryseobacterium	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF302,TPR_2
XH1_k127_1717587_1	1123277.KB893173_gene1725	4.835e-54	211.0	COG0793@1|root,COG0793@2|Bacteria,4NFEN@976|Bacteroidetes,47PTG@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Tricorn_C1
XH1_k127_1717587_0	1047013.AQSP01000098_gene2571	9.538e-116	387.0	COG3579@1|root,COG3579@2|Bacteria	2|Bacteria	E	homocysteine catabolic process	-	-	3.4.22.40	ko:K01372,ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03032	-	-	-	Peptidase_C1,Peptidase_C1_2
XH1_k127_1717587_2	1163407.UU7_05623	2.647e-33	134.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	yrgI	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
XH1_k127_1732735_1	1047013.AQSP01000067_gene2199	2.188e-74	266.0	COG3379@1|root,COG3379@2|Bacteria,2NQEW@2323|unclassified Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
XH1_k127_1732735_2	1254432.SCE1572_34170	1.931e-63	235.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2WJYY@28221|Deltaproteobacteria,2Z30P@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
XH1_k127_1732735_0	247490.KSU1_C1246	2.857e-105	349.0	COG3379@1|root,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
XH1_k127_1818483_7	706587.Desti_0011	1.294e-08	60.0	COG1014@1|root,COG1014@2|Bacteria,1R8XG@1224|Proteobacteria,42NPD@68525|delta/epsilon subdivisions,2WMQ1@28221|Deltaproteobacteria,2MRSP@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
XH1_k127_1818483_3	1125863.JAFN01000001_gene1977	6.979e-87	310.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
XH1_k127_1818483_1	1499967.BAYZ01000154_gene1507	3.566e-121	399.0	COG0674@1|root,COG0674@2|Bacteria,2NPPN@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
XH1_k127_1818483_6	456320.Mvol_1273	1.021e-13	75.0	COG1146@1|root,arCOG00959@2157|Archaea,2XZY3@28890|Euryarchaeota,23R9B@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
XH1_k127_1818483_5	457570.Nther_1481	4.018e-20	91.0	COG1146@1|root,COG1146@2|Bacteria,1VFGN@1239|Firmicutes,25FSQ@186801|Clostridia	186801|Clostridia	C	PFAM 4Fe-4S	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Fer4_9
XH1_k127_1818483_0	1121468.AUBR01000007_gene242	1.838e-139	454.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,42FG2@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
XH1_k127_1818483_2	398767.Glov_1628	1.424e-103	346.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria,43SWR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM thiamine pyrophosphate	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
XH1_k127_1818483_4	243231.GSU1470	3.651e-56	201.0	COG1014@1|root,COG1014@2|Bacteria,1RAQ4@1224|Proteobacteria,43BEE@68525|delta/epsilon subdivisions,2WN0D@28221|Deltaproteobacteria,43TV8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	korC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
XH1_k127_1899231_2	379066.GAU_1726	4.837e-18	86.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
XH1_k127_1899231_0	645991.Sgly_3063	9.665e-64	226.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,262J6@186807|Peptococcaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
XH1_k127_1899231_1	1123057.P872_24035	9.686e-48	173.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,47JQI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
XH1_k127_191987_7	439235.Dalk_2032	4.153e-101	341.0	COG2267@1|root,COG2267@2|Bacteria,1QYAK@1224|Proteobacteria,43ECK@68525|delta/epsilon subdivisions,2WVYY@28221|Deltaproteobacteria,2MPDV@213118|Desulfobacterales	1224|Proteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
XH1_k127_191987_3	935845.JADQ01000029_gene1230	5.003e-144	496.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
XH1_k127_191987_31	880073.Calab_0913	3.241e-19	104.0	COG1523@1|root,COG1523@2|Bacteria	2|Bacteria	G	belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
XH1_k127_191987_0	56780.SYN_00674	1.638e-252	786.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,42MTV@68525|delta/epsilon subdivisions,2WKVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
XH1_k127_191987_9	1379698.RBG1_1C00001G0936	7.586e-78	266.0	COG1335@1|root,COG1335@2|Bacteria,2NRGH@2323|unclassified Bacteria	2|Bacteria	Q	Isochorismatase family	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
XH1_k127_191987_8	1304875.JAFZ01000002_gene336	9.347e-91	312.0	COG1752@1|root,COG1752@2|Bacteria,3TC9C@508458|Synergistetes	508458|Synergistetes	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
XH1_k127_191987_24	1403819.BATR01000117_gene4029	1.261e-28	131.0	COG0526@1|root,COG0526@2|Bacteria,46TGF@74201|Verrucomicrobia,2IW4P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
XH1_k127_191987_22	575540.Isop_0603	8.644e-33	136.0	COG1186@1|root,COG1186@2|Bacteria,2J05G@203682|Planctomycetes	203682|Planctomycetes	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
XH1_k127_191987_15	748280.NH8B_2419	1.738e-59	211.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,2VRSU@28216|Betaproteobacteria,2KRT1@206351|Neisseriales	206351|Neisseriales	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
XH1_k127_191987_14	1499967.BAYZ01000156_gene556	2.893e-60	223.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K20444	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
XH1_k127_191987_38	1220589.CD32_15750	0.0001158	55.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,4HAU0@91061|Bacilli	91061|Bacilli	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
XH1_k127_191987_27	47839.CCAU010000011_gene5810	1.425e-23	109.0	COG3340@1|root,COG3340@2|Bacteria,2IC7Y@201174|Actinobacteria,234WT@1762|Mycobacteriaceae	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
XH1_k127_191987_37	1121875.KB907547_gene3432	8.37e-06	55.0	28WBK@1|root,2ZIC0@2|Bacteria,4P7B5@976|Bacteroidetes,1IBE5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_191987_36	1123057.P872_23860	3.19e-06	57.0	2DSJJ@1|root,33GER@2|Bacteria,4NZAF@976|Bacteroidetes,47UN4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_191987_29	452637.Oter_1881	2.858e-22	104.0	COG1680@1|root,COG4319@1|root,COG1680@2|Bacteria,COG4319@2|Bacteria,46V0A@74201|Verrucomicrobia,3K85Q@414999|Opitutae	414999|Opitutae	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
XH1_k127_191987_20	1232437.KL661972_gene4775	4.066e-40	166.0	COG0500@1|root,COG2226@2|Bacteria,1NNI3@1224|Proteobacteria,4321D@68525|delta/epsilon subdivisions,2WX0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
XH1_k127_191987_17	1123368.AUIS01000033_gene1380	3.93e-50	196.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
XH1_k127_191987_19	316067.Geob_0985	1.287e-40	158.0	COG3467@1|root,COG3467@2|Bacteria,1N4RH@1224|Proteobacteria,42TKQ@68525|delta/epsilon subdivisions,2WQ06@28221|Deltaproteobacteria,43VAD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
XH1_k127_191987_2	56780.SYN_01159	1.969e-145	475.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WMDC@28221|Deltaproteobacteria,2MREJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
XH1_k127_191987_13	1301098.PKB_0807	2.265e-66	236.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
XH1_k127_191987_12	1499967.BAYZ01000023_gene261	7.71e-67	247.0	COG2267@1|root,COG2267@2|Bacteria,2NQB7@2323|unclassified Bacteria	2|Bacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
XH1_k127_191987_21	483219.LILAB_19665	1.038e-37	151.0	2ESNI@1|root,33K73@2|Bacteria,1Q2MV@1224|Proteobacteria,4388I@68525|delta/epsilon subdivisions,2X3I7@28221|Deltaproteobacteria,2YW7A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
XH1_k127_191987_32	1168034.FH5T_14775	7.363e-18	87.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_191987_34	865937.Gilli_3252	3.325e-12	68.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1I507@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
XH1_k127_191987_16	518766.Rmar_0576	4.145e-57	213.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
XH1_k127_191987_23	1121405.dsmv_3521	1.285e-29	122.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	mutT5	-	3.6.1.55,3.6.1.65	ko:K03574,ko:K08320	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
XH1_k127_191987_1	1499967.BAYZ01000102_gene3560	1.224e-151	490.0	COG1092@1|root,COG1092@2|Bacteria,2NPFM@2323|unclassified Bacteria	2|Bacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.191,2.1.1.264	ko:K06969,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
XH1_k127_191987_4	404589.Anae109_1169	1.253e-138	463.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2Z1IJ@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
XH1_k127_191987_33	32057.KB217478_gene2361	3.344e-13	72.0	COG4877@1|root,COG4877@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
XH1_k127_191987_5	945713.IALB_0203	2.779e-125	407.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
XH1_k127_191987_10	1047013.AQSP01000140_gene2494	1.761e-71	260.0	COG2234@1|root,COG2234@2|Bacteria,2NRCG@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
XH1_k127_191987_26	379066.GAU_1101	3.204e-24	112.0	COG2834@1|root,COG2834@2|Bacteria,1ZUW4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_191987_6	234267.Acid_0851	5.028e-108	372.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
XH1_k127_191987_25	660470.Theba_2385	1.689e-27	116.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
XH1_k127_191987_18	176299.Atu1565	3.278e-42	164.0	COG1045@1|root,COG1045@2|Bacteria,1RM0T@1224|Proteobacteria,2U8N8@28211|Alphaproteobacteria,4BD1K@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
XH1_k127_191987_11	304371.MCP_0824	3.641e-71	263.0	COG4912@1|root,arCOG05122@2157|Archaea,2Y8HF@28890|Euryarchaeota	28890|Euryarchaeota	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
XH1_k127_19278_4	1121930.AQXG01000004_gene2869	1.041e-20	95.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	prtA	-	3.2.1.23,3.4.24.40	ko:K01190,ko:K01406,ko:K07004,ko:K13277	ko00052,ko00511,ko00600,ko01100,ko01503,ko02024,map00052,map00511,map00600,map01100,map01503,map02024	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Gram_pos_anchor,HemolysinCabind,PA,Peptidase_S8,SLH,fn3_5
XH1_k127_19278_2	309807.SRU_1922	1.403e-51	208.0	COG4089@1|root,COG4089@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
XH1_k127_19278_0	1047013.AQSP01000126_gene2741	1.048e-285	894.0	COG0339@1|root,COG0339@2|Bacteria,2NP9Q@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M3	prlC	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
XH1_k127_19278_1	1480694.DC28_07580	2.636e-89	306.0	COG0167@1|root,COG0167@2|Bacteria,2J972@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.1.1,1.3.98.1	ko:K00226,ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
XH1_k127_19278_3	886293.Sinac_0560	3.445e-33	136.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	mgsA	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat,DSPc,MGS
XH1_k127_193734_13	370438.PTH_1182	6.161e-07	56.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,26022@186807|Peptococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
XH1_k127_193734_12	1131730.BAVI_18152	7.173e-10	67.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,1ZIVS@1386|Bacillus	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
XH1_k127_193734_3	204669.Acid345_3432	1.239e-62	234.0	COG0142@1|root,COG0142@2|Bacteria,3Y2HS@57723|Acidobacteria,2JIPK@204432|Acidobacteriia	204432|Acidobacteriia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
XH1_k127_193734_11	1408422.JHYF01000001_gene2839	2.439e-13	77.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,36KSA@31979|Clostridiaceae	186801|Clostridia	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
XH1_k127_193734_0	1121468.AUBR01000002_gene654	1.414e-214	683.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,42EPX@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
XH1_k127_193734_5	760568.Desku_1925	6.145e-49	188.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,260CC@186807|Peptococcaceae	186801|Clostridia	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
XH1_k127_193734_2	439235.Dalk_3718	2.007e-79	296.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2MHTD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
XH1_k127_193734_9	5334.XP_003032752.1	8.522e-16	91.0	COG2234@1|root,KOG2195@2759|Eukaryota,38HFK@33154|Opisthokonta,3NVAW@4751|Fungi,3V9F1@5204|Basidiomycota,22BP6@155619|Agaricomycetes,3W9RS@5338|Agaricales	4751|Fungi	OP	to MEROPS metallopeptidase family M28E	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
XH1_k127_193734_6	215803.DB30_6730	3.878e-47	183.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q7A@68525|delta/epsilon subdivisions,2WM81@28221|Deltaproteobacteria,2YW8C@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
XH1_k127_193734_1	880073.Calab_2000	2.03e-105	351.0	COG0451@1|root,COG0451@2|Bacteria,2NNNX@2323|unclassified Bacteria	2|Bacteria	GM	NAD(P)H-binding	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
XH1_k127_193734_10	768671.ThimaDRAFT_0396	4.702e-15	86.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,1WZDX@135613|Chromatiales	135613|Chromatiales	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
XH1_k127_193734_14	340177.Cag_0649	3.062e-05	57.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	wzc	-	-	ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,GNVR,Wzz
XH1_k127_193734_7	880073.Calab_3531	7.471e-33	145.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
XH1_k127_193734_8	1265503.KB905160_gene2733	2.5e-18	99.0	COG2931@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,1PIDH@1224|Proteobacteria,1SXX5@1236|Gammaproteobacteria,2Q7Y4@267889|Colwelliaceae	1236|Gammaproteobacteria	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
XH1_k127_193734_4	756272.Plabr_1344	2.178e-62	224.0	COG2148@1|root,COG2148@2|Bacteria,2IX7E@203682|Planctomycetes	203682|Planctomycetes	M	involved in lipopolysaccharide	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
XH1_k127_1945315_2	1396141.BATP01000056_gene3201	8.03e-36	143.0	COG1404@1|root,COG3210@1|root,COG4412@1|root,COG5492@1|root,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4412@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Peptidase_S8,fn3
XH1_k127_1945315_1	314345.SPV1_12235	2.203e-53	210.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria	1224|Proteobacteria	U	UPF0056 membrane protein	ychE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
XH1_k127_1945315_0	880073.Calab_2517	7.685e-158	507.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
XH1_k127_1945315_3	1349767.GJA_1093	2.653e-08	66.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,472XP@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport system, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
XH1_k127_2081661_4	1304284.L21TH_0413	3.194e-08	64.0	COG1579@1|root,COG1579@2|Bacteria,1VKTP@1239|Firmicutes,24JFI@186801|Clostridia,36JGI@31979|Clostridiaceae	186801|Clostridia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
XH1_k127_2081661_2	650150.ERH_0005	1.641e-25	111.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,3VPJU@526524|Erysipelotrichia	526524|Erysipelotrichia	GT	COG COG1299 Phosphotransferase system, fructose-specific IIC component	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
XH1_k127_2081661_0	518766.Rmar_1702	7.989e-68	243.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1FIU8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
XH1_k127_2081661_1	1191523.MROS_0141	1.051e-30	136.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	waaC	-	-	ko:K02841,ko:K02843,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
XH1_k127_2081661_3	1042877.GQS_00080	8.844e-16	82.0	arCOG03264@1|root,arCOG03264@2157|Archaea,2Y50J@28890|Euryarchaeota,244SG@183968|Thermococci	183968|Thermococci	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
XH1_k127_212196_1	1379270.AUXF01000001_gene2297	1.816e-08	65.0	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,1ZUB7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
XH1_k127_212196_0	1121468.AUBR01000069_gene1116	5.379e-129	441.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,42EQJ@68295|Thermoanaerobacterales	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
XH1_k127_214178_1	517417.Cpar_1838	5.298e-78	273.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
XH1_k127_214178_2	880072.Desac_2419	7.639e-65	246.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2WKGK@28221|Deltaproteobacteria,2MQEH@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
XH1_k127_214178_0	1123242.JH636436_gene620	1.048e-105	354.0	COG3437@1|root,COG3437@2|Bacteria,2IXR5@203682|Planctomycetes	203682|Planctomycetes	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Pkinase,Response_reg
XH1_k127_214178_3	1121022.ABENE_13990	1.397e-28	130.0	COG0412@1|root,COG0412@2|Bacteria,1QZEH@1224|Proteobacteria	1224|Proteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH,TPR_2
XH1_k127_2146126_1	290317.Cpha266_0557	4.292e-42	168.0	COG3074@1|root,COG3074@2|Bacteria,1FFHR@1090|Chlorobi	1090|Chlorobi	D	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2146126_0	1047013.AQSP01000134_gene1338	3.816e-158	514.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
XH1_k127_2146126_2	555088.DealDRAFT_2256	1.836e-23	105.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia	186801|Clostridia	E	vitamin B12 dependent methionine synthase, activation	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
XH1_k127_216277_1	1047013.AQSP01000071_gene1939	1.147e-55	202.0	COG1297@1|root,COG1297@2|Bacteria,2NP0C@2323|unclassified Bacteria	2|Bacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
XH1_k127_216277_0	330214.NIDE0254	5.521e-127	418.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
XH1_k127_216277_2	234267.Acid_6886	1.208e-12	80.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_217822_3	429009.Adeg_0173	4.595e-112	398.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07714,ko:K10943	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_217822_7	1232410.KI421424_gene1590	1.656e-43	175.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43C4K@68525|delta/epsilon subdivisions,2X7F1@28221|Deltaproteobacteria,43TX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains HisKA, HATPase_c	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
XH1_k127_217822_9	1353529.M899_1091	3.608e-14	84.0	COG0737@1|root,COG0737@2|Bacteria,1ND4P@1224|Proteobacteria,42W6F@68525|delta/epsilon subdivisions,2WRWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	Cytochrome_C554
XH1_k127_217822_5	398767.Glov_0049	9.08e-68	242.0	COG3481@1|root,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria,43T29@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	nucleic acid binding OB-fold tRNA helicase-type	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
XH1_k127_217822_4	264732.Moth_2167	4.316e-96	341.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,42EZ0@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
XH1_k127_217822_1	1121430.JMLG01000003_gene532	8.653e-138	449.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
XH1_k127_217822_6	226185.EF_0174	9.765e-64	229.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,4AZRJ@81852|Enterococcaceae	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00835	DeoC
XH1_k127_217822_2	404589.Anae109_0662	2.76e-114	383.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales	28221|Deltaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
XH1_k127_217822_0	1379698.RBG1_1C00001G1562	6.79e-171	561.0	COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
XH1_k127_217822_8	411460.RUMTOR_02807	4.178e-17	81.0	2BRU1@1|root,32KU6@2|Bacteria,1U1G4@1239|Firmicutes,25NUE@186801|Clostridia,3Y201@572511|Blautia	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2251057_0	929556.Solca_2759	1.37e-222	702.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQ80@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
XH1_k127_2251057_10	459349.CLOAM1790	1.464e-18	101.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
XH1_k127_2251057_11	1122212.AULO01000011_gene549	2.357e-17	97.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,1SZVW@1236|Gammaproteobacteria,1XN7J@135619|Oceanospirillales	135619|Oceanospirillales	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2251057_9	1280390.CBQR020000151_gene4031	1.846e-20	106.0	COG1807@1|root,COG1807@2|Bacteria,1UYMG@1239|Firmicutes,4HB8M@91061|Bacilli,26ZKF@186822|Paenibacillaceae	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_2251057_14	756067.MicvaDRAFT_2430	0.0009413	52.0	COG0457@1|root,COG1215@1|root,COG1216@1|root,COG0457@2|Bacteria,COG1215@2|Bacteria,COG1216@2|Bacteria,1GQBE@1117|Cyanobacteria,1H7DT@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,RgpF,TPR_1,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
XH1_k127_2251057_1	195522.BD01_1707	9.024e-183	583.0	COG0591@1|root,arCOG01316@2157|Archaea,2XTJ2@28890|Euryarchaeota,245F2@183968|Thermococci	183968|Thermococci	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
XH1_k127_2251057_4	518766.Rmar_2903	1.398e-116	390.0	2CA5R@1|root,2Z81H@2|Bacteria,4NGSF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
XH1_k127_2251057_12	307480.IW16_15530	9.968e-13	81.0	COG4783@1|root,COG4783@2|Bacteria,4NJ2X@976|Bacteroidetes,1I05N@117743|Flavobacteriia,3ZT3R@59732|Chryseobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
XH1_k127_2251057_8	392499.Swit_1105	1.621e-51	205.0	COG1228@1|root,COG1228@2|Bacteria,1R7HE@1224|Proteobacteria,2VFGS@28211|Alphaproteobacteria,2K5QR@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
XH1_k127_2251057_6	1379698.RBG1_1C00001G1218	2.446e-115	407.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
XH1_k127_2251057_2	96561.Dole_3137	1.726e-177	564.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42NJU@68525|delta/epsilon subdivisions,2WKA6@28221|Deltaproteobacteria,2MJK5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
XH1_k127_2251057_7	192952.MM_3157	8.298e-70	250.0	COG1680@1|root,arCOG00771@2157|Archaea	2157|Archaea	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A1202	Beta-lactamase
XH1_k127_2251057_3	521045.Kole_0614	2.177e-146	487.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06889,ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,Malectin,Peptidase_S9
XH1_k127_2251057_5	1379698.RBG1_1C00001G1218	9.095e-116	407.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
XH1_k127_2285469_0	215803.DB30_7421	4.004e-230	727.0	COG1164@1|root,COG1164@2|Bacteria,1Q3C4@1224|Proteobacteria,4393F@68525|delta/epsilon subdivisions,2X49B@28221|Deltaproteobacteria,2YYJ7@29|Myxococcales	28221|Deltaproteobacteria	E	Oligoendopeptidase f	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2285469_7	1304284.L21TH_0712	1.72e-125	409.0	COG0451@1|root,COG0451@2|Bacteria,1TSUN@1239|Firmicutes,2485S@186801|Clostridia,36FJ8@31979|Clostridiaceae	186801|Clostridia	M	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
XH1_k127_2285469_3	1442599.JAAN01000032_gene1514	3.319e-171	546.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1X3NP@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
XH1_k127_2285469_1	457570.Nther_2013	1.275e-216	693.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia	186801|Clostridia	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
XH1_k127_2285469_13	77635.BISU_0864	0.0008567	50.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ24@85004|Bifidobacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
XH1_k127_2285469_10	330214.NIDE0678	2.363e-11	74.0	COG2217@1|root,COG2217@2|Bacteria,3J0CY@40117|Nitrospirae	40117|Nitrospirae	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
XH1_k127_2285469_8	518766.Rmar_0027	3.139e-97	330.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1FJ4H@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
XH1_k127_2285469_9	485915.Dret_0332	3.623e-14	80.0	COG1371@1|root,COG1371@2|Bacteria,1N301@1224|Proteobacteria	1224|Proteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
XH1_k127_2285469_2	479434.Sthe_3251	1.965e-180	576.0	COG1690@1|root,COG1690@2|Bacteria,2G5NT@200795|Chloroflexi,27XP1@189775|Thermomicrobia	189775|Thermomicrobia	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
XH1_k127_2285469_6	316067.Geob_1902	2.426e-141	462.0	COG0535@1|root,COG0535@2|Bacteria,1Q4F6@1224|Proteobacteria,42Z23@68525|delta/epsilon subdivisions,2WU1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
XH1_k127_2285469_4	880073.Calab_1356	4.065e-162	527.0	COG1305@1|root,COG1305@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	TIG,Transglut_core
XH1_k127_2285469_5	679897.HMU08020	1.121e-157	515.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2YMDX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
XH1_k127_2285469_11	1056820.KB900658_gene4138	2.746e-10	70.0	2EZNE@1|root,33STF@2|Bacteria,1QZHA@1224|Proteobacteria,1T46W@1236|Gammaproteobacteria,2PQ6Y@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2285469_12	913325.N799_02355	9.652e-06	51.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1S7VF@1236|Gammaproteobacteria,1X54J@135614|Xanthomonadales	135614|Xanthomonadales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB1	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
XH1_k127_2286150_2	1499967.BAYZ01000028_gene1312	7.669e-113	387.0	COG1117@1|root,COG1117@2|Bacteria,2NP2B@2323|unclassified Bacteria	2|Bacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27,3.6.3.55	ko:K02036,ko:K02068,ko:K06857	ko02010,map02010	M00186,M00211,M00222	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.7	-	-	ABC_tran
XH1_k127_2286150_3	1499967.BAYZ01000028_gene1313	7.071e-109	388.0	COG0581@1|root,COG0581@2|Bacteria,2NPJS@2323|unclassified Bacteria	2|Bacteria	P	phosphate transport system permease protein	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
XH1_k127_2286150_0	1499967.BAYZ01000028_gene1314	3.035e-124	404.0	COG0573@1|root,COG0573@2|Bacteria,2NPS2@2323|unclassified Bacteria	2|Bacteria	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
XH1_k127_2286150_1	1499967.BAYZ01000028_gene1315	6.998e-124	405.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
XH1_k127_2370748_9	1121406.JAEX01000006_gene2156	3.993e-93	312.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,42NU5@68525|delta/epsilon subdivisions,2WJV4@28221|Deltaproteobacteria,2M8EH@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
XH1_k127_2370748_4	335543.Sfum_3452	8.935e-181	579.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,2MQXX@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
XH1_k127_2370748_21	1304885.AUEY01000011_gene1737	1.322e-24	105.0	COG0695@1|root,COG0695@2|Bacteria,1NAZM@1224|Proteobacteria,42VIA@68525|delta/epsilon subdivisions,2WR8X@28221|Deltaproteobacteria,2MKPI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM Glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
XH1_k127_2370748_16	1121405.dsmv_3380	2.152e-50	186.0	COG4802@1|root,COG4802@2|Bacteria,1RI70@1224|Proteobacteria,42SXJ@68525|delta/epsilon subdivisions,2WP19@28221|Deltaproteobacteria,2MKJ4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
XH1_k127_2370748_14	665571.STHERM_c19690	8.49e-57	212.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K03769,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
XH1_k127_2370748_20	1232410.KI421415_gene3082	1.101e-25	111.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
XH1_k127_2370748_11	1121403.AUCV01000032_gene2908	8.228e-85	295.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,42R2C@68525|delta/epsilon subdivisions,2WMZ7@28221|Deltaproteobacteria,2MKAM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
XH1_k127_2370748_5	247490.KSU1_D0580	4.756e-176	564.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	treT	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
XH1_k127_2370748_12	247490.KSU1_D0579	2.035e-70	251.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gtf2	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2370748_18	671143.DAMO_1531	1.208e-40	162.0	COG1877@1|root,COG1877@2|Bacteria,2NPXY@2323|unclassified Bacteria	2|Bacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K01087,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	iE2348C_1286.E2348C_2018,iECED1_1282.ECED1_2163,iECIAI39_1322.ECIAI39_1155,iECS88_1305.ECS88_1952,iLF82_1304.LF82_1582,iNRG857_1313.NRG857_09495	Glyco_hydro_15,Glyco_transf_20,Trehalose_PPase
XH1_k127_2370748_3	1379698.RBG1_1C00001G0655	5.874e-199	662.0	COG0380@1|root,COG0380@2|Bacteria,2NPDG@2323|unclassified Bacteria	2|Bacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135	ko:K00697,ko:K13057,ko:K20436	ko00500,ko00525,ko01100,ko01130,map00500,map00525,map01100,map01130	M00815	R02737,R08946,R10525,R11239,R11250,R11306,R11497	RC00005,RC00049,RC02748,RC03400,RC03401	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT20,GT4	-	Glyco_transf_20
XH1_k127_2370748_10	266117.Rxyl_1210	1.605e-90	311.0	COG0668@1|root,COG0668@2|Bacteria,2GZI1@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
XH1_k127_2370748_17	754027.HMPREF9554_00423	1.169e-41	159.0	COG0425@1|root,COG2210@1|root,COG0425@2|Bacteria,COG2210@2|Bacteria	2|Bacteria	P	Belongs to the sulfur carrier protein TusA family	cdr	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
XH1_k127_2370748_13	985053.VMUT_2339	9.981e-67	240.0	COG0247@1|root,COG2048@1|root,arCOG00964@2157|Archaea,arCOG05014@2157|Archaea	2157|Archaea	C	Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane	hdrE	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0031224,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0044425,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576	1.8.98.1	ko:K08265,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	Fer4_17,Nitrate_red_gam
XH1_k127_2370748_1	1121422.AUMW01000009_gene3349	3.749e-224	715.0	COG1148@1|root,COG1148@2|Bacteria,1V5YJ@1239|Firmicutes,248CC@186801|Clostridia,260ZH@186807|Peptococcaceae	186801|Clostridia	C	binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
XH1_k127_2370748_0	1121472.AQWN01000008_gene1913	0.0	1053.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
XH1_k127_2370748_15	1121472.AQWN01000008_gene1912	2.274e-51	187.0	COG1908@1|root,COG1908@2|Bacteria,1V80C@1239|Firmicutes,24MB7@186801|Clostridia,264Z4@186807|Peptococcaceae	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
XH1_k127_2370748_22	935863.AWZR01000004_gene448	4.942e-16	85.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1X7P3@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
XH1_k127_2370748_19	747365.Thena_0467	2.69e-26	113.0	COG0425@1|root,COG0425@2|Bacteria,1VJRT@1239|Firmicutes,24V06@186801|Clostridia	186801|Clostridia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
XH1_k127_2370748_6	1048829.XP_002796315.1	3.446e-154	500.0	COG0520@1|root,KOG2142@2759|Eukaryota,38F30@33154|Opisthokonta,3NY5Z@4751|Fungi,3QREF@4890|Ascomycota,20FDX@147545|Eurotiomycetes,3B2AK@33183|Onygenales,3FQBE@34383|Onygenales incertae sedis	4751|Fungi	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
XH1_k127_2370748_8	118166.JH976537_gene3002	2.185e-99	339.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
XH1_k127_2370748_2	1121405.dsmv_0170	2.327e-207	675.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2MHT0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
XH1_k127_2370748_23	1122138.AQUZ01000013_gene5710	1.896e-15	92.0	COG1621@1|root,COG1621@2|Bacteria,2I9BS@201174|Actinobacteria	201174|Actinobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
XH1_k127_2370748_25	1407650.BAUB01000006_gene1432	2.866e-11	78.0	COG2133@1|root,COG2133@2|Bacteria,1GP2C@1117|Cyanobacteria,1H24N@1129|Synechococcus	1117|Cyanobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2370748_26	880073.Calab_2549	1.895e-07	66.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
XH1_k127_2370748_7	697281.Mahau_0952	2.474e-118	392.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,42ER8@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
XH1_k127_2378822_3	1121481.AUAS01000004_gene1678	2.392e-06	58.0	294MN@1|root,2ZS13@2|Bacteria,4P817@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2378822_1	1121448.DGI_0215	3.82e-54	208.0	2BF3Y@1|root,315AZ@2|Bacteria,1NCT0@1224|Proteobacteria,42Y21@68525|delta/epsilon subdivisions,2WXJ4@28221|Deltaproteobacteria,2MFU5@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4055
XH1_k127_2378822_0	1335760.ASTG01000033_gene40	2.77e-163	523.0	COG1783@1|root,COG1783@2|Bacteria	2|Bacteria	S	DNA packaging	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
XH1_k127_2408578_3	926692.AZYG01000019_gene206	1.786e-41	162.0	COG2870@1|root,COG2870@2|Bacteria,1TSMF@1239|Firmicutes,24FJA@186801|Clostridia,3WA7M@53433|Halanaerobiales	186801|Clostridia	M	TIGRFAM rfaE bifunctional protein, domain I	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
XH1_k127_2408578_2	438753.AZC_2251	7.262e-43	170.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2TSXD@28211|Alphaproteobacteria,3F0VS@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	waaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
XH1_k127_2408578_1	926692.AZYG01000040_gene1543	3.518e-130	437.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WA9Z@53433|Halanaerobiales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
XH1_k127_2408578_5	926561.KB900617_gene2106	9.221e-14	83.0	COG0859@1|root,COG0859@2|Bacteria,1UYYX@1239|Firmicutes,24ETA@186801|Clostridia,3WA7I@53433|Halanaerobiales	186801|Clostridia	M	PFAM Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
XH1_k127_2408578_0	1499967.BAYZ01000139_gene157	3.801e-251	797.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
XH1_k127_2408578_4	1304885.AUEY01000031_gene47	4.282e-15	81.0	COG0071@1|root,COG0071@2|Bacteria,1RE2H@1224|Proteobacteria,42RP0@68525|delta/epsilon subdivisions,2WNC4@28221|Deltaproteobacteria,2MK0Y@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
XH1_k127_2408578_6	1500259.JQLD01000023_gene1571	0.0008605	49.0	COG5305@1|root,COG5305@2|Bacteria,1R9UF@1224|Proteobacteria,2VC2T@28211|Alphaproteobacteria,4BDHZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_2417715_2	1232410.KI421428_gene1054	9.014e-92	313.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_2417715_0	880073.Calab_3385	2.995e-97	336.0	COG2204@1|root,COG2204@2|Bacteria,2NQDH@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	fhlA	-	-	ko:K03413,ko:K13589	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506,M00512	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_2417715_3	945713.IALB_2930	6.06e-50	192.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2417715_1	383372.Rcas_0946	1.656e-92	321.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi,374V0@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
XH1_k127_2426142_2	1378168.N510_02453	4.508e-52	197.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes	1239|Firmicutes	S	Stress-induced protein	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
XH1_k127_2426142_1	742722.HMPREF9463_01670	5.28e-53	199.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CVKY@84998|Coriobacteriia	84998|Coriobacteriia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
XH1_k127_2426142_3	1235797.C816_03289	0.0002798	45.0	COG1758@1|root,COG1758@2|Bacteria,1VII0@1239|Firmicutes,24SVW@186801|Clostridia,2N7S4@216572|Oscillospiraceae	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
XH1_k127_2426142_0	396588.Tgr7_0102	1.974e-72	251.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales	135613|Chromatiales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
XH1_k127_2451679_6	400682.PAC_15706214	1.016e-64	244.0	2CZW5@1|root,2SBX5@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
XH1_k127_2451679_3	1123393.KB891316_gene1158	2.914e-88	324.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2W93J@28216|Betaproteobacteria,1KTEE@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
XH1_k127_2451679_4	629773.AORY01000021_gene2352	7.501e-74	262.0	COG0438@1|root,COG0438@2|Bacteria,1R3TV@1224|Proteobacteria,2TUG4@28211|Alphaproteobacteria,2K69X@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
XH1_k127_2451679_7	1123489.AUAN01000002_gene604	2.939e-48	180.0	COG0279@1|root,COG0279@2|Bacteria,1V5W5@1239|Firmicutes,4H4BA@909932|Negativicutes	909932|Negativicutes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
XH1_k127_2451679_8	515635.Dtur_0599	1.512e-40	168.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
XH1_k127_2451679_0	760568.Desku_2025	9.717e-235	755.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,260FP@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
XH1_k127_2451679_12	937777.Deipe_3584	1.735e-10	70.0	COG2137@1|root,COG2137@2|Bacteria,1WKKC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
XH1_k127_2451679_1	1125863.JAFN01000001_gene3030	3.488e-144	467.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
XH1_k127_2451679_2	452637.Oter_1467	4.138e-118	396.0	COG2067@1|root,COG2067@2|Bacteria,46U6Z@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
XH1_k127_2451679_9	977880.RALTA_B0678	6.755e-37	152.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,2VJV0@28216|Betaproteobacteria,1KH2P@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
XH1_k127_2451679_10	671143.DAMO_2617	1.315e-23	108.0	COG1514@1|root,COG1514@2|Bacteria,2NPRT@2323|unclassified Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
XH1_k127_2451679_5	521011.Mpal_0671	4.674e-71	248.0	arCOG02576@1|root,arCOG02576@2157|Archaea,2XZNM@28890|Euryarchaeota,2N9WU@224756|Methanomicrobia	224756|Methanomicrobia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
XH1_k127_2451679_11	326424.FRAAL5732	4.09e-11	65.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4ERZM@85013|Frankiales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
XH1_k127_249176_3	264732.Moth_0480	0.0007034	52.0	COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes,25EBC@186801|Clostridia,42HI5@68295|Thermoanaerobacterales	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
XH1_k127_249176_2	1297617.JPJD01000016_gene152	1.64e-26	126.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,268PV@186813|unclassified Clostridiales	186801|Clostridia	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
XH1_k127_249176_1	56780.SYN_01340	3.368e-27	126.0	COG1082@1|root,COG1082@2|Bacteria,1N8KJ@1224|Proteobacteria,42SR1@68525|delta/epsilon subdivisions,2WP5P@28221|Deltaproteobacteria,2MQKJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
XH1_k127_249176_0	1047013.AQSP01000094_gene20	7.585e-192	619.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
XH1_k127_251957_1	290402.Cbei_3018	1.239e-113	383.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,36E70@31979|Clostridiaceae	186801|Clostridia	C	flavodoxin nitric oxide synthase	norV	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B
XH1_k127_251957_2	644282.Deba_3003	2.917e-28	119.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	bgeR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
XH1_k127_251957_0	335543.Sfum_0738	7.361e-114	380.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2MQEQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
XH1_k127_2551848_0	675817.VDA_000430	9.364e-15	88.0	COG1361@1|root,COG1404@1|root,COG2304@1|root,COG3291@1|root,COG3391@1|root,COG3420@1|root,COG4719@1|root,COG4932@1|root,COG5184@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG2304@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3420@2|Bacteria,COG4719@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,1R59C@1224|Proteobacteria,1SDEC@1236|Gammaproteobacteria,1XVUF@135623|Vibrionales	135623|Vibrionales	DMPZ	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11
XH1_k127_2551848_1	596151.DesfrDRAFT_0577	0.000215	44.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2M8SG@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
XH1_k127_2553925_2	96561.Dole_0808	1.745e-05	50.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria,2MMZK@213118|Desulfobacterales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_2553925_0	96561.Dole_0809	1.435e-91	307.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria,2MIZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
XH1_k127_2553925_1	96561.Dole_0810	5.738e-87	296.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria,2MJ2Q@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
XH1_k127_2586547_0	1047013.AQSP01000094_gene32	1.127e-170	544.0	COG0017@1|root,COG0017@2|Bacteria,2NNQM@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class II (D, K and N)	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
XH1_k127_2604456_1	1121930.AQXG01000002_gene2009	1.328e-62	245.0	COG3536@1|root,COG3536@2|Bacteria,4PKQ9@976|Bacteroidetes,1IRMG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2604456_2	1191523.MROS_0530	6.173e-33	146.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
XH1_k127_2604456_0	161156.JQKW01000012_gene64	4.602e-144	468.0	COG0422@1|root,COG0422@2|Bacteria,2GGW7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
XH1_k127_2604456_3	696281.Desru_2232	7.897e-21	107.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,25C6H@186801|Clostridia,2601V@186807|Peptococcaceae	186801|Clostridia	L	helicase involved in DNA repair and perhaps also replication	dinG	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T,RadC,ResIII
XH1_k127_26383_6	1313304.CALK_0618	4.519e-05	48.0	COG1198@1|root,COG1198@2|Bacteria	2|Bacteria	L	DNA replication, synthesis of RNA primer	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
XH1_k127_26383_5	240015.ACP_1098	5.035e-08	65.0	COG0457@1|root,COG0457@2|Bacteria,3Y35N@57723|Acidobacteria,2JHIM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
XH1_k127_26383_0	1379698.RBG1_1C00001G0312	4.116e-203	640.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
XH1_k127_26383_4	869209.Tresu_1226	1.866e-28	116.0	COG0254@1|root,COG0254@2|Bacteria,2J93Z@203691|Spirochaetes	203691|Spirochaetes	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
XH1_k127_26383_2	401526.TcarDRAFT_1421	1.925e-65	234.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H271@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
XH1_k127_26383_1	335543.Sfum_1713	7.868e-127	416.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2MQ5C@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
XH1_k127_26383_3	1125863.JAFN01000001_gene1724	1.21e-54	203.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
XH1_k127_2651593_1	1042375.AFPL01000046_gene2013	6.938e-10	64.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria,468EX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	DUF167	yggU	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
XH1_k127_2651593_0	1379698.RBG1_1C00001G1616	1.827e-48	196.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
XH1_k127_2674409_0	760568.Desku_3183	1.388e-315	984.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,26059@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
XH1_k127_2674409_7	886293.Sinac_6415	2.751e-88	310.0	COG3869@1|root,COG3869@2|Bacteria,2IXJG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
XH1_k127_2674409_13	189425.PGRAT_29510	5.784e-35	139.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,26R52@186822|Paenibacillaceae	91061|Bacilli	S	protein with conserved CXXC pairs	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
XH1_k127_2674409_9	1158318.ATXC01000001_gene145	5.803e-69	241.0	COG1136@1|root,COG1136@2|Bacteria,2G4P0@200783|Aquificae	200783|Aquificae	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
XH1_k127_2674409_8	589865.DaAHT2_1307	1.663e-74	274.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MHM1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
XH1_k127_2674409_2	880073.Calab_1380	1.283e-166	550.0	COG1190@1|root,COG1190@2|Bacteria,2NNMH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
XH1_k127_2674409_5	1158318.ATXC01000001_gene1139	8.626e-119	391.0	COG1186@1|root,COG1186@2|Bacteria,2G3P3@200783|Aquificae	200783|Aquificae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
XH1_k127_2674409_17	3702.AT2G27490.2	5.698e-14	82.0	COG0237@1|root,KOG3220@2759|Eukaryota,37RNA@33090|Viridiplantae,3G96N@35493|Streptophyta,3HRKZ@3699|Brassicales	35493|Streptophyta	H	dephospho-CoA kinase	-	GO:0003674,GO:0003824,GO:0004140,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005777,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009507,GO:0009536,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
XH1_k127_2674409_1	1232410.KI421418_gene2160	3.659e-241	774.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,43RY4@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase A domain	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
XH1_k127_2674409_12	1210884.HG799463_gene9385	2.056e-35	145.0	COG1057@1|root,COG1057@2|Bacteria,2IZMU@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
XH1_k127_2674409_14	1379698.RBG1_1C00001G0869	3.408e-21	104.0	COG4105@1|root,COG4105@2|Bacteria,2NPZ3@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	yfiO	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
XH1_k127_2674409_18	314607.KB13_253	0.0001337	53.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
XH1_k127_2674409_6	272563.CD630_13260	4.471e-92	327.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,25QPV@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
XH1_k127_2674409_3	1121405.dsmv_2597	6.261e-136	463.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MI69@213118|Desulfobacterales	28221|Deltaproteobacteria	D	DNA segregation ATPase, FtsK SpoIIIE family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
XH1_k127_2674409_11	292564.Cyagr_1237	1.52e-40	170.0	COG0352@1|root,COG0352@2|Bacteria,1G1VB@1117|Cyanobacteria,22S40@167375|Cyanobium	1117|Cyanobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.thiE	TMP-TENI
XH1_k127_2674409_10	1121930.AQXG01000014_gene379	1.736e-42	165.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IPNP@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ComB family	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
XH1_k127_2674409_4	1232410.KI421428_gene1170	2.185e-126	415.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,43TYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
XH1_k127_2674409_15	861299.J421_3537	3.923e-17	93.0	COG0457@1|root,COG0457@2|Bacteria,1ZTTU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
XH1_k127_2674409_16	1124780.ANNU01000028_gene1001	3.056e-16	90.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,47NDQ@768503|Cytophagia	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
XH1_k127_2695949_1	1131269.AQVV01000034_gene2274	1.201e-16	92.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	3.1.21.3	ko:K01153,ko:K05789,ko:K07011,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01005,ko02000,ko02048	8.A.3.1	-	-	GNVR,Wzz
XH1_k127_2695949_2	1144275.COCOR_05030	2.615e-15	89.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,42VMH@68525|delta/epsilon subdivisions,2WS8Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
XH1_k127_2695949_0	42256.RradSPS_1688	9.252e-45	182.0	COG1807@1|root,COG1807@2|Bacteria,2GNPY@201174|Actinobacteria	201174|Actinobacteria	M	capsule polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2695949_3	1229203.KI301992_gene675	5.034e-13	71.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
XH1_k127_277116_1	65393.PCC7424_5194	4.878e-61	227.0	COG0177@1|root,COG0177@2|Bacteria,1G1VI@1117|Cyanobacteria,3KHKS@43988|Cyanothece	1117|Cyanobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
XH1_k127_277116_3	886293.Sinac_7264	8.479e-16	84.0	COG2897@1|root,COG3271@1|root,COG2897@2|Bacteria,COG3271@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	DUF3335,Peptidase_C39,Peptidase_C39_2,Rhodanese,TPR_16,TPR_19,TPR_2,TPR_8
XH1_k127_277116_4	331678.Cphamn1_1657	4.216e-08	64.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	mauE	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
XH1_k127_277116_2	1499967.BAYZ01000155_gene619	6.877e-28	126.0	2E1HF@1|root,32WVJ@2|Bacteria,2NRFV@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3996
XH1_k127_277116_0	269799.Gmet_1640	6.711e-138	450.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,43TVR@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
XH1_k127_277116_5	1121267.JHZL01000013_gene22	1.383e-06	55.0	COG3350@1|root,COG4393@1|root,COG3350@2|Bacteria,COG4393@2|Bacteria,1R507@1224|Proteobacteria,42NQA@68525|delta/epsilon subdivisions,2YM97@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318,YHS
XH1_k127_2772921_5	1123239.KB898623_gene1677	1.099e-41	158.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli	91061|Bacilli	C	COG0277 FAD FMN-containing dehydrogenases	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
XH1_k127_2772921_0	760568.Desku_0428	5.092e-103	353.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25ZZB@186807|Peptococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
XH1_k127_2772921_1	1170562.Cal6303_1055	5.253e-99	341.0	COG4826@1|root,COG4826@2|Bacteria,1G29E@1117|Cyanobacteria,1HIIV@1161|Nostocales	1117|Cyanobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
XH1_k127_2772921_8	666510.ASAC_0514	1.165e-06	58.0	COG0454@1|root,arCOG00826@2157|Archaea,2XR3W@28889|Crenarchaeota	28889|Crenarchaeota	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
XH1_k127_2772921_6	1169161.KB897731_gene269	6.21e-37	157.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
XH1_k127_2772921_3	1408473.JHXO01000012_gene318	6.57e-82	279.0	COG1131@1|root,COG1131@2|Bacteria,4NMN9@976|Bacteroidetes	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_2772921_2	153721.MYP_1718	9.62e-88	302.0	COG0842@1|root,COG0842@2|Bacteria,4NKB0@976|Bacteroidetes	976|Bacteroidetes	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
XH1_k127_2772921_4	1123234.AUKI01000008_gene993	9.249e-66	244.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,1I15D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
XH1_k127_2772921_7	10160.XP_004624987.1	1.748e-14	85.0	28K3T@1|root,2QSIA@2759|Eukaryota,3974K@33154|Opisthokonta,3BBX0@33208|Metazoa,3CV1I@33213|Bilateria,485N6@7711|Chordata,4962A@7742|Vertebrata,3JD7X@40674|Mammalia,35B3B@314146|Euarchontoglires,4PVC6@9989|Rodentia	33208|Metazoa	S	Protein of unknown function (DUF2723)	TMEM260	-	-	-	-	-	-	-	-	-	-	-	DUF2723
XH1_k127_2773609_0	1408473.JHXO01000007_gene803	3.038e-131	428.0	COG0436@1|root,COG0436@2|Bacteria,4NJTV@976|Bacteroidetes,2FMKZ@200643|Bacteroidia	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
XH1_k127_2784194_3	1121406.JAEX01000006_gene2156	1.28e-105	352.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,42NU5@68525|delta/epsilon subdivisions,2WJV4@28221|Deltaproteobacteria,2M8EH@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
XH1_k127_2784194_0	530564.Psta_3379	5.056e-181	576.0	COG1509@1|root,COG1509@2|Bacteria,2IYGS@203682|Planctomycetes	203682|Planctomycetes	C	lysine 2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,LAM_C,Radical_SAM
XH1_k127_2784194_2	1121405.dsmv_1836	9.904e-134	433.0	COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,42SA1@68525|delta/epsilon subdivisions,2WNIR@28221|Deltaproteobacteria,2MIAX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
XH1_k127_2784194_4	1121396.KB893079_gene871	3.274e-101	340.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2MHWK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
XH1_k127_2784194_6	1167006.UWK_00109	1.684e-50	185.0	COG0123@1|root,COG0454@1|root,COG0123@2|Bacteria,COG0456@2|Bacteria,1MU7P@1224|Proteobacteria,42NAQ@68525|delta/epsilon subdivisions,2WJPX@28221|Deltaproteobacteria,2MK5E@213118|Desulfobacterales	28221|Deltaproteobacteria	BKQ	Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Hist_deacetyl
XH1_k127_2784194_7	404589.Anae109_1378	3.264e-46	183.0	COG0585@1|root,COG0585@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
XH1_k127_2784194_5	1304885.AUEY01000001_gene3203	1.798e-61	226.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
XH1_k127_2784194_10	1304885.AUEY01000001_gene3204	9.507e-30	126.0	2DPAK@1|root,33193@2|Bacteria,1NDU6@1224|Proteobacteria,432ZD@68525|delta/epsilon subdivisions,2WYIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_2784194_11	1499967.BAYZ01000050_gene2842	2.416e-26	109.0	COG0526@1|root,COG0526@2|Bacteria,2NQ71@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
XH1_k127_2784194_1	1499967.BAYZ01000050_gene2840	1.698e-170	543.0	COG0701@1|root,COG0701@2|Bacteria,2NP6A@2323|unclassified Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
XH1_k127_2784194_8	1499967.BAYZ01000050_gene2839	7.626e-34	133.0	COG0640@1|root,COG0640@2|Bacteria,2NQ13@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	3.6.4.12	ko:K03655,ko:K03892	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	HTH_20,HTH_5
XH1_k127_2784194_9	644282.Deba_2053	1.441e-33	134.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,42TU6@68525|delta/epsilon subdivisions,2WPZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
XH1_k127_2784194_12	335543.Sfum_0347	8.59e-14	74.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,2MQMZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
XH1_k127_2855155_0	118163.Ple7327_0425	3.211e-159	511.0	COG0436@1|root,COG0436@2|Bacteria,1GHX7@1117|Cyanobacteria,3VM7E@52604|Pleurocapsales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
XH1_k127_2855155_2	56780.SYN_01213	1.789e-95	323.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,42M16@68525|delta/epsilon subdivisions,2WM0V@28221|Deltaproteobacteria,2MRCH@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Amino acid kinase family	cpkA	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
XH1_k127_2855155_3	768704.Desmer_0789	1.605e-62	232.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,261WJ@186807|Peptococcaceae	186801|Clostridia	S	conserved protein (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
XH1_k127_2855155_1	546271.Selsp_1021	6.145e-136	446.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
XH1_k127_2855155_4	1537915.JU57_08310	1.367e-39	153.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2YNW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
XH1_k127_2855155_5	290397.Adeh_2454	3.996e-13	80.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42UBZ@68525|delta/epsilon subdivisions,2WQ0E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the SUA5 family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
XH1_k127_2879466_0	742817.HMPREF9449_02421	4.976e-123	418.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,2FPYJ@200643|Bacteroidia,22XFT@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
XH1_k127_2879466_9	203275.BFO_0431	2.773e-12	80.0	COG1305@1|root,COG1305@2|Bacteria,4NIJF@976|Bacteroidetes,2FQJU@200643|Bacteroidia,22XJ6@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
XH1_k127_2879466_8	401526.TcarDRAFT_1917	1.224e-12	72.0	COG1430@1|root,COG1430@2|Bacteria,1VF55@1239|Firmicutes,4H5P7@909932|Negativicutes	909932|Negativicutes	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
XH1_k127_2879466_4	871968.DESME_14475	2.186e-57	216.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia	186801|Clostridia	M	Group 1 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
XH1_k127_2879466_1	1278073.MYSTI_02808	3.808e-94	325.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
XH1_k127_2879466_7	502025.Hoch_6883	8.867e-24	109.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2WPZ9@28221|Deltaproteobacteria,2YV95@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_2879466_11	240015.ACP_2048	1.76e-07	64.0	COG1040@1|root,COG1040@2|Bacteria,3Y5KW@57723|Acidobacteria,2JMCD@204432|Acidobacteriia	204432|Acidobacteriia	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DZR,PLDc_N
XH1_k127_2879466_5	1232410.KI421428_gene1010	7.38e-43	160.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,42SID@68525|delta/epsilon subdivisions,2WQ86@28221|Deltaproteobacteria,43SGS@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	nickel-responsive regulator	nikR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
XH1_k127_2879466_3	309801.trd_A0604	2.512e-58	225.0	COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
XH1_k127_2879466_6	246969.TAM4_850	8.219e-32	143.0	COG0619@1|root,arCOG02250@2157|Archaea,2XV2C@28890|Euryarchaeota	28890|Euryarchaeota	P	ABC-type cobalt transport system, permease component CbiQ and related	cbiQ1	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
XH1_k127_2879466_10	264732.Moth_1863	1.569e-11	75.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,42FFY@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM	nikMN	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
XH1_k127_2879466_2	944479.JQLX01000011_gene695	9.749e-59	209.0	COG0310@1|root,COG0310@2|Bacteria,1PK7P@1224|Proteobacteria,43A69@68525|delta/epsilon subdivisions,2X22Y@28221|Deltaproteobacteria,2M7KF@213113|Desulfurellales	28221|Deltaproteobacteria	P	Cobalt uptake substrate-specific transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CbiM
XH1_k127_2892961_1	768710.DesyoDRAFT_3880	1.387e-21	109.0	COG0860@1|root,COG2247@1|root,COG3103@1|root,COG0860@2|Bacteria,COG2247@2|Bacteria,COG3103@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,260BF@186807|Peptococcaceae	186801|Clostridia	M	Cell Wall	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Big_4,Big_5,CW_binding_2,SH3_3,SPOR
XH1_k127_2892961_0	1121430.JMLG01000005_gene718	3.752e-110	372.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,2608U@186807|Peptococcaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
XH1_k127_2892961_2	44251.PDUR_06000	0.000715	50.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,26QBB@186822|Paenibacillaceae	91061|Bacilli	D	Tyrosine protein kinase	epsB	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
XH1_k127_28984_3	886293.Sinac_6637	4.885e-27	113.0	COG1163@1|root,COG1163@2|Bacteria,2IWYP@203682|Planctomycetes	203682|Planctomycetes	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
XH1_k127_28984_1	383372.Rcas_0549	1.683e-88	305.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,374VN@32061|Chloroflexia	32061|Chloroflexia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
XH1_k127_28984_0	1047013.AQSP01000105_gene1443	0.0	1522.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
XH1_k127_28984_4	1122998.AUHZ01000002_gene2114	1.349e-15	87.0	COG0737@1|root,COG0737@2|Bacteria,2GKC3@201174|Actinobacteria,4DMYT@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the 5'-nucleotidase family	cpdB	-	3.1.3.5,3.1.3.6,3.1.4.16	ko:K01081,ko:K01119	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
XH1_k127_28984_2	667014.Thein_0942	1.445e-81	305.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,2GIQQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
XH1_k127_2909388_0	1379698.RBG1_1C00001G1523	1.705e-54	213.0	COG4775@1|root,COG4775@2|Bacteria,2NQXR@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
XH1_k127_2909388_1	869213.JCM21142_104555	2.667e-11	78.0	COG2911@1|root,COG2911@2|Bacteria,4NSGX@976|Bacteroidetes	976|Bacteroidetes	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA,TamB
XH1_k127_2916010_3	573413.Spirs_0981	1.289e-14	79.0	COG0203@1|root,COG0203@2|Bacteria,2J841@203691|Spirochaetes	203691|Spirochaetes	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
XH1_k127_2916010_1	1123284.KB899045_gene2362	2.125e-36	151.0	COG0679@1|root,COG0679@2|Bacteria,1UEYG@1239|Firmicutes,4HD45@91061|Bacilli,26P2M@186821|Sporolactobacillaceae	91061|Bacilli	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
XH1_k127_2916010_2	598659.NAMH_0817	1.013e-15	91.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2YMAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycolate oxidase subunit	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
XH1_k127_2916010_0	1121428.DESHY_110357___1	1.907e-53	210.0	COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,24AIF@186801|Clostridia,261A8@186807|Peptococcaceae	186801|Clostridia	C	PFAM Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
XH1_k127_2969271_0	357808.RoseRS_3698	7.835e-105	356.0	COG0448@1|root,COG0448@2|Bacteria,2G7W8@200795|Chloroflexi,374YT@32061|Chloroflexia	32061|Chloroflexia	H	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
XH1_k127_2969271_1	880073.Calab_3649	1.182e-80	289.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2NP1D@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase SLT domain	CP_0155	-	-	ko:K08307,ko:K12204	-	-	-	-	ko00000,ko01000,ko01011,ko02044	3.A.7.10.1,3.A.7.9.1	-	-	LysM,SLT,T4SS_TraI
XH1_k127_2994845_1	189753.AXAS01000004_gene956	3.124e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1NG0U@1224|Proteobacteria,2U0YA@28211|Alphaproteobacteria,3K0QN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
XH1_k127_2994845_0	1120972.AUMH01000016_gene2238	2.958e-13	74.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
XH1_k127_299744_4	204669.Acid345_1213	1.914e-60	213.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria,2JIRS@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
XH1_k127_299744_5	1304888.ATWF01000001_gene2361	3.391e-53	205.0	COG0544@1|root,COG0544@2|Bacteria,2GESH@200930|Deferribacteres	200930|Deferribacteres	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
XH1_k127_299744_3	648996.Theam_0136	7.217e-81	280.0	COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae	200783|Aquificae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
XH1_k127_299744_1	867903.ThesuDRAFT_00639	9.155e-175	557.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WCCB@538999|Clostridiales incertae sedis	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
XH1_k127_299744_0	743299.Acife_1403	8.074e-257	815.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,2NCCV@225057|Acidithiobacillales	225057|Acidithiobacillales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
XH1_k127_299744_7	1345697.M493_13725	1.883e-49	182.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,1WEZ3@129337|Geobacillus	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
XH1_k127_299744_6	1123373.ATXI01000021_gene921	6.889e-52	201.0	COG0075@1|root,COG0075@2|Bacteria,2GH1F@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
XH1_k127_299744_8	65071.PYU1_T010912	0.0001077	50.0	2EAHJ@1|root,2SGRB@2759|Eukaryota,1MJMA@121069|Pythiales	121069|Pythiales	S	ATP-binding Cassette (ABC) Superfamily. Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_299744_2	717231.Flexsi_0623	1.068e-129	432.0	COG0104@1|root,COG0104@2|Bacteria,2GEUU@200930|Deferribacteres	200930|Deferribacteres	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
XH1_k127_3001824_10	443144.GM21_1727	4.601e-63	237.0	COG5316@1|root,COG5316@2|Bacteria,1N0IJ@1224|Proteobacteria	1224|Proteobacteria	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
XH1_k127_3001824_0	502025.Hoch_6136	6.413e-224	713.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42Q48@68525|delta/epsilon subdivisions,2X5G4@28221|Deltaproteobacteria,2YZF5@29|Myxococcales	28221|Deltaproteobacteria	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
XH1_k127_3001824_6	554065.XP_005849456.1	1.859e-93	328.0	COG0616@1|root,2QQH5@2759|Eukaryota,37JSU@33090|Viridiplantae,34JKR@3041|Chlorophyta	3041|Chlorophyta	OU	protease IV	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
XH1_k127_3001824_13	1121459.AQXE01000001_gene2715	2.18e-10	74.0	COG1633@1|root,COG1633@2|Bacteria,1N997@1224|Proteobacteria,42VKE@68525|delta/epsilon subdivisions,2WRKQ@28221|Deltaproteobacteria,2MC42@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_3001824_5	1191523.MROS_0148	2.36e-101	346.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
XH1_k127_3001824_2	945713.IALB_0266	1.098e-172	554.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrome_C554
XH1_k127_3001824_4	572547.Amico_0219	1.085e-103	343.0	COG0428@1|root,COG0428@2|Bacteria,3T9UW@508458|Synergistetes	508458|Synergistetes	P	PFAM zinc iron permease	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
XH1_k127_3001824_3	880072.Desac_2167	2.544e-113	393.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MRV@68525|delta/epsilon subdivisions,2WK9C@28221|Deltaproteobacteria,2MR5B@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
XH1_k127_3001824_1	880072.Desac_2166	1e-210	669.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2MRG4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
XH1_k127_3001824_11	2423.NA23_0201340	2.367e-55	198.0	COG1528@1|root,COG1528@2|Bacteria,2GD4M@200918|Thermotogae	200918|Thermotogae	P	Iron-storage protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
XH1_k127_3001824_9	573370.DMR_17610	4.358e-64	220.0	COG2033@1|root,COG2033@2|Bacteria,1RHE0@1224|Proteobacteria,42SB9@68525|delta/epsilon subdivisions,2WP2D@28221|Deltaproteobacteria,2MBEZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Desulfoferrodoxin ferrous iron-binding region	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
XH1_k127_3001824_7	338963.Pcar_2346	1.276e-83	301.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,43SE2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_3001824_14	1111069.TCCBUS3UF1_19440	2.903e-06	59.0	COG2608@1|root,COG2608@2|Bacteria,1WKNR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Heavy metal transport detoxification protein	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
XH1_k127_3001824_8	1232410.KI421421_gene3809	1.072e-81	287.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,43S3G@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
XH1_k127_3001824_12	335543.Sfum_0347	7.115e-44	166.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,2MQMZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
XH1_k127_3133139_1	1198452.Jab_2c15010	3.141e-29	124.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_3133139_3	187272.Mlg_0258	2.872e-10	68.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WVVT@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_3133139_0	1121918.ARWE01000001_gene3313	9.327e-76	271.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_3133139_2	1033732.CAHI01000030_gene1147	6.782e-11	76.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,2FPJR@200643|Bacteroidia,22U0P@171550|Rikenellaceae	976|Bacteroidetes	T	histidine kinase DNA gyrase B	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
XH1_k127_3133139_4	743836.AYNA01000145_gene563	0.0004566	43.0	COG0776@1|root,COG0776@2|Bacteria,1N6FS@1224|Proteobacteria,2V9XC@28211|Alphaproteobacteria,3708U@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Bacterial DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
XH1_k127_3221553_1	1033743.CAES01000002_gene1777	6.245e-57	208.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli,26VCR@186822|Paenibacillaceae	91061|Bacilli	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
XH1_k127_3221553_2	575540.Isop_1160	1.736e-10	74.0	COG0457@1|root,COG0859@1|root,COG3063@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,COG3063@2|Bacteria,2IYBQ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
XH1_k127_3221553_0	1384049.CD29_02850	3.138e-86	293.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,3IWV5@400634|Lysinibacillus	91061|Bacilli	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
XH1_k127_3256606_1	246197.MXAN_3583	1.483e-17	90.0	COG1164@1|root,COG1164@2|Bacteria,1Q3C4@1224|Proteobacteria,4393F@68525|delta/epsilon subdivisions,2X49B@28221|Deltaproteobacteria,2YYJ7@29|Myxococcales	28221|Deltaproteobacteria	E	Oligoendopeptidase f	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3256606_0	1206739.BAGJ01000088_gene379	2.775e-39	154.0	COG1974@1|root,COG1974@2|Bacteria,2I9XR@201174|Actinobacteria,4FX8U@85025|Nocardiaceae	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
XH1_k127_3350669_0	880073.Calab_1878	6.522e-161	516.0	2CD20@1|root,2Z7SQ@2|Bacteria,2NNUF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3375693_6	56780.SYN_00357	6.511e-66	235.0	COG1351@1|root,COG1351@2|Bacteria,1QF4I@1224|Proteobacteria,43A0P@68525|delta/epsilon subdivisions,2X9Q1@28221|Deltaproteobacteria,2MSCD@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Thymidylate synthase complementing protein	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
XH1_k127_3375693_2	880073.Calab_1396	2.849e-133	463.0	COG0729@1|root,COG0823@1|root,COG0729@2|Bacteria,COG0823@2|Bacteria,2NRA2@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	treP	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,PD40
XH1_k127_3375693_4	445975.COLSTE_00864	1.863e-104	352.0	COG0409@1|root,COG0409@2|Bacteria,2GMHA@201174|Actinobacteria,4CUKQ@84998|Coriobacteriia	84998|Coriobacteriia	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
XH1_k127_3375693_19	1321778.HMPREF1982_03233	6.559e-16	81.0	COG0298@1|root,COG0298@2|Bacteria	2|Bacteria	O	carbon dioxide binding	hypC	-	-	ko:K04653,ko:K04654	-	-	-	-	ko00000	-	-	-	HupF_HypC
XH1_k127_3375693_7	198628.Dda3937_01820	3.487e-65	235.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,2JDR8@204037|Dickeya	1236|Gammaproteobacteria	KO	PFAM cobalamin synthesis protein P47K	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
XH1_k127_3375693_17	69042.WH5701_06486	9.287e-21	98.0	COG0375@1|root,COG0375@2|Bacteria,1G89Y@1117|Cyanobacteria,1H1N4@1129|Synechococcus	1117|Cyanobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
XH1_k127_3375693_13	1449126.JQKL01000002_gene1553	1.506e-33	136.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
XH1_k127_3375693_1	767817.Desgi_1166	7.947e-182	577.0	COG3259@1|root,COG3259@2|Bacteria,1UZNV@1239|Firmicutes,24F0H@186801|Clostridia,2644W@186807|Peptococcaceae	186801|Clostridia	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
XH1_k127_3375693_16	1121422.AUMW01000038_gene3023	1.764e-22	110.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
XH1_k127_3375693_3	429009.Adeg_2014	7.482e-113	373.0	COG1941@1|root,COG1941@2|Bacteria,1V21E@1239|Firmicutes,24GWD@186801|Clostridia,42HGR@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
XH1_k127_3375693_8	429009.Adeg_2015	1.14e-63	222.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
XH1_k127_3375693_0	693661.Arcve_1567	3.969e-243	768.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
XH1_k127_3375693_5	1379698.RBG1_1C00001G0051	8.679e-90	304.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
XH1_k127_3375693_11	1449126.JQKL01000002_gene1547	5.168e-47	176.0	COG1150@1|root,COG1150@2|Bacteria,1V27J@1239|Firmicutes,24FU5@186801|Clostridia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
XH1_k127_3375693_20	906968.Trebr_1845	8.398e-11	74.0	COG0457@1|root,COG0457@2|Bacteria,2J5NB@203691|Spirochaetes	203691|Spirochaetes	S	tetratricopeptide repeat	lmp1	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
XH1_k127_3375693_9	1121430.JMLG01000025_gene85	4.362e-54	202.0	COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,24DN8@186801|Clostridia,261B5@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
XH1_k127_3375693_14	1120973.AQXL01000135_gene1400	3.529e-31	133.0	COG1852@1|root,COG1852@2|Bacteria,1V1B5@1239|Firmicutes,4HUDI@91061|Bacilli,279H3@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116
XH1_k127_3375693_15	580331.Thit_1470	2.89e-24	108.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,42JDU@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
XH1_k127_3375693_12	913865.DOT_5322	8.883e-38	163.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
XH1_k127_3375693_18	1191523.MROS_1634	2.344e-18	100.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_1634|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3375693_10	1047013.AQSP01000098_gene2574	5.555e-52	196.0	COG0778@1|root,COG0778@2|Bacteria,2NQ10@2323|unclassified Bacteria	2|Bacteria	C	Putative TM nitroreductase	noxC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
XH1_k127_3386507_0	85643.Tmz1t_1473	1.464e-168	556.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
XH1_k127_3413643_6	682795.AciX8_3367	1.526e-36	159.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
XH1_k127_3413643_0	1123277.KB893172_gene561	3.053e-172	565.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KFX@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
XH1_k127_3413643_3	880072.Desac_2465	2.482e-71	252.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,42S95@68525|delta/epsilon subdivisions,2WNPS@28221|Deltaproteobacteria,2MRNY@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,YkuD
XH1_k127_3413643_4	269799.Gmet_3487	4.939e-42	160.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42TV7@68525|delta/epsilon subdivisions,2WRW0@28221|Deltaproteobacteria,43TY1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,YkuD
XH1_k127_3413643_1	1047013.AQSP01000105_gene1439	2.318e-117	392.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	MA20_31530	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
XH1_k127_3413643_5	1254432.SCE1572_24695	8.911e-37	153.0	COG0500@1|root,COG2226@2|Bacteria,1PVPS@1224|Proteobacteria,43DGN@68525|delta/epsilon subdivisions,2X8NF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3413643_2	552811.Dehly_0247	4.344e-105	353.0	COG0309@1|root,COG0309@2|Bacteria,2G7TM@200795|Chloroflexi,34CX4@301297|Dehalococcoidia	301297|Dehalococcoidia	O	AIR synthase related protein, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
XH1_k127_3463993_3	880073.Calab_2182	2.415e-12	73.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
XH1_k127_3463993_1	1307759.JOMJ01000004_gene2502	9.445e-36	153.0	COG2244@1|root,COG2244@2|Bacteria,1NB5K@1224|Proteobacteria,43AXB@68525|delta/epsilon subdivisions,2X6BJ@28221|Deltaproteobacteria,2MH0Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
XH1_k127_3463993_0	269797.Mbar_A0185	1.093e-63	232.0	COG0037@1|root,arCOG15275@2157|Archaea,2Y0EE@28890|Euryarchaeota,2NB74@224756|Methanomicrobia	224756|Methanomicrobia	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	QueC
XH1_k127_3463993_2	526227.Mesil_0612	5.491e-13	74.0	COG0566@1|root,COG0566@2|Bacteria,1WJ5I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind,TSNR_N
XH1_k127_3516185_21	1254432.SCE1572_42465	5.7e-23	107.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2YVCY@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
XH1_k127_3516185_3	351627.Csac_1189	4.321e-104	347.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,42EMP@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ketose-bisphosphate aldolase, class-II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
XH1_k127_3516185_2	880073.Calab_3781	1.175e-135	440.0	COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
XH1_k127_3516185_0	324925.Ppha_2906	4.162e-138	450.0	COG0126@1|root,COG0126@2|Bacteria,1FDBD@1090|Chlorobi	1090|Chlorobi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
XH1_k127_3516185_8	1191523.MROS_1843	3.438e-72	258.0	COG0149@1|root,COG0149@2|Bacteria	2|Bacteria	G	triose-phosphate isomerase activity	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
XH1_k127_3516185_25	1123371.ATXH01000004_gene1711	4.294e-10	66.0	COG1314@1|root,COG1314@2|Bacteria,2GI2G@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
XH1_k127_3516185_24	1303518.CCALI_02008	4.592e-11	71.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
XH1_k127_3516185_13	1379698.RBG1_1C00001G1850	4.606e-47	177.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
XH1_k127_3516185_1	518766.Rmar_2366	3.461e-137	459.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1FIKX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
XH1_k127_3516185_27	234267.Acid_4336	3.985e-06	60.0	COG4805@1|root,COG4805@2|Bacteria,3Y47D@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
XH1_k127_3516185_20	767817.Desgi_2980	1.214e-26	126.0	COG1333@1|root,COG1333@2|Bacteria,1TQ6C@1239|Firmicutes,24HES@186801|Clostridia,261WA@186807|Peptococcaceae	186801|Clostridia	O	ResB protein required for cytochrome c biosynthesis	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
XH1_k127_3516185_14	264732.Moth_2200	1.064e-43	183.0	COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,24BCK@186801|Clostridia,42IAC@68295|Thermoanaerobacterales	186801|Clostridia	O	Cytochrome C assembly protein	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
XH1_k127_3516185_26	880073.Calab_3296	1.603e-09	70.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
XH1_k127_3516185_28	378806.STAUR_1752	1.201e-05	58.0	COG2247@1|root,COG2247@2|Bacteria,1PDF4@1224|Proteobacteria,4393C@68525|delta/epsilon subdivisions,2X497@28221|Deltaproteobacteria,2YYIZ@29|Myxococcales	28221|Deltaproteobacteria	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3516185_4	401526.TcarDRAFT_1875	2.182e-97	341.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
XH1_k127_3516185_11	596151.DesfrDRAFT_0241	1.35e-59	228.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2M8Z2@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
XH1_k127_3516185_6	1336208.JADY01000018_gene3258	4.198e-86	299.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQJC@28211|Alphaproteobacteria,2JWAA@204441|Rhodospirillales	204441|Rhodospirillales	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
XH1_k127_3516185_12	443144.GM21_1592	7.598e-53	208.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
XH1_k127_3516185_5	404589.Anae109_0384	5.222e-92	314.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Thiamine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
XH1_k127_3516185_17	96561.Dole_2285	8.907e-38	148.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,42T3V@68525|delta/epsilon subdivisions,2WPYF@28221|Deltaproteobacteria,2MKDN@213118|Desulfobacterales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
XH1_k127_3516185_9	237368.SCABRO_00251	1.655e-70	253.0	COG0524@1|root,COG0524@2|Bacteria,2IX8I@203682|Planctomycetes	203682|Planctomycetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
XH1_k127_3516185_15	926550.CLDAP_03000	5.488e-41	157.0	COG0622@1|root,COG0622@2|Bacteria,2G7DJ@200795|Chloroflexi	200795|Chloroflexi	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
XH1_k127_3516185_16	237368.SCABRO_03463	6.17e-41	173.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,2J0AC@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH1_k127_3516185_10	383372.Rcas_1378	4.429e-61	220.0	COG1912@1|root,COG1912@2|Bacteria,2G6NI@200795|Chloroflexi,376J1@32061|Chloroflexia	32061|Chloroflexia	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
XH1_k127_3516185_19	880073.Calab_0082	3.211e-35	141.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_3516185_18	502025.Hoch_1519	5.553e-37	142.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,42UIZ@68525|delta/epsilon subdivisions,2WQ43@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
XH1_k127_3516185_7	880073.Calab_0865	2.176e-75	273.0	COG0491@1|root,COG0491@2|Bacteria,2NPRD@2323|unclassified Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
XH1_k127_3516185_22	1223521.BBJX01000005_gene1890	4.259e-22	106.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2VQPE@28216|Betaproteobacteria,4ADGF@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_3516185_30	1246995.AFR_01190	0.0005928	51.0	COG5660@1|root,COG5660@2|Bacteria,2IHDZ@201174|Actinobacteria,4DD83@85008|Micromonosporales	201174|Actinobacteria	S	Putative zinc-finger	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	zf-HC2
XH1_k127_3516185_29	1340493.JNIF01000003_gene3985	1.414e-05	56.0	COG3678@1|root,COG3678@2|Bacteria,3Y5A6@57723|Acidobacteria	57723|Acidobacteria	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
XH1_k127_353615_2	335543.Sfum_0762	1.332e-11	73.0	COG1538@1|root,COG1538@2|Bacteria,1QY91@1224|Proteobacteria,42Q4F@68525|delta/epsilon subdivisions,2WJMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
XH1_k127_353615_1	246194.CHY_0088	5.364e-21	105.0	COG0845@1|root,COG0845@2|Bacteria,1V158@1239|Firmicutes,25CIT@186801|Clostridia,42ET6@68295|Thermoanaerobacterales	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
XH1_k127_353615_0	1499967.BAYZ01000028_gene1227	2.361e-221	723.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
XH1_k127_3574786_2	1120966.AUBU01000002_gene1883	1.187e-05	59.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI1V@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
XH1_k127_3574786_0	1125863.JAFN01000001_gene1583	1.383e-94	320.0	COG2404@1|root,COG2404@2|Bacteria,1QW0R@1224|Proteobacteria,43BQN@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	COG0618 Exopolyphosphatase-related proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3574786_1	177437.HRM2_15520	2.987e-25	106.0	COG2248@1|root,COG2248@2|Bacteria,1PW56@1224|Proteobacteria,42Y9V@68525|delta/epsilon subdivisions,2WU2Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative, 10TM heavy-metal exporter	-	-	-	ko:K07022	-	-	-	-	ko00000	-	-	-	ArsP_2
XH1_k127_361782_2	880073.Calab_2769	1.579e-16	81.0	COG1734@1|root,COG1734@2|Bacteria,2NPX2@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulator, TraR DksA family	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
XH1_k127_361782_1	1196324.A374_11975	1.718e-27	117.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli	91061|Bacilli	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
XH1_k127_361782_0	1379698.RBG1_1C00001G0106	8.299e-97	332.0	COG0564@1|root,COG0564@2|Bacteria,2NNY5@2323|unclassified Bacteria	2|Bacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432	PseudoU_synth_2,S4
XH1_k127_369176_0	4432.XP_010276986.1	8.541e-33	146.0	COG4870@1|root,KOG1543@2759|Eukaryota,37TGB@33090|Viridiplantae,3GFEW@35493|Streptophyta	33090|Viridiplantae	O	Belongs to the peptidase C1 family	-	-	-	ko:K16290	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Inhibitor_I29,Peptidase_C1
XH1_k127_3773225_2	1379698.RBG1_1C00001G0842	1.263e-70	249.0	COG1181@1|root,COG1181@2|Bacteria,2NPB2@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
XH1_k127_3773225_1	401526.TcarDRAFT_2204	1.734e-103	347.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H27Q@909932|Negativicutes	909932|Negativicutes	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
XH1_k127_3773225_0	443143.GM18_4230	1.171e-142	494.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,43TS3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
XH1_k127_3773225_7	1121447.JONL01000001_gene735	4.465e-05	50.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3773225_3	1499967.BAYZ01000113_gene2944	4.515e-18	83.0	COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria	2|Bacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
XH1_k127_3775232_0	1217720.ALOX01000011_gene2534	7.052e-62	222.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
XH1_k127_3775232_1	1499967.BAYZ01000089_gene5033	5.087e-52	192.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
XH1_k127_3775232_3	518766.Rmar_2394	2.008e-10	73.0	COG0737@1|root,COG4677@1|root,COG0737@2|Bacteria,COG4677@2|Bacteria,4PNDC@976|Bacteroidetes,1FJX0@1100069|Bacteroidetes Order II. Incertae sedis	2|Bacteria	F	pectinesterase activity	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	Beta_helix,Lipase_GDSL_2,NosD,Pectate_lyase_3,SBP_bac_8
XH1_k127_3775232_4	153721.MYP_2074	0.0005388	52.0	COG3469@1|root,COG3693@1|root,COG3469@2|Bacteria,COG3693@2|Bacteria,4NHWH@976|Bacteroidetes,47P4R@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
XH1_k127_3775232_2	2045.KR76_08180	1.191e-51	201.0	COG1524@1|root,COG1524@2|Bacteria,2HY6Q@201174|Actinobacteria,4DT1Q@85009|Propionibacteriales	201174|Actinobacteria	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
XH1_k127_379091_13	861299.J421_4162	1.088e-27	117.0	COG0795@1|root,COG0795@2|Bacteria,1ZTJR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
XH1_k127_379091_10	1379698.RBG1_1C00001G1857	1.802e-62	228.0	COG0795@1|root,COG0795@2|Bacteria,2NPHN@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
XH1_k127_379091_16	204669.Acid345_4467	5.439e-14	85.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria,2JIG4@204432|Acidobacteriia	204432|Acidobacteriia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_379091_0	1379698.RBG1_1C00001G1855	2.186e-184	585.0	COG0499@1|root,COG0499@2|Bacteria,2NNQE@2323|unclassified Bacteria	2|Bacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
XH1_k127_379091_2	1267535.KB906767_gene3229	9.895e-156	501.0	COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria,2JJ0A@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
XH1_k127_379091_5	517418.Ctha_2572	1.232e-91	328.0	COG1209@1|root,COG1209@2|Bacteria,1FD8Z@1090|Chlorobi	1090|Chlorobi	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
XH1_k127_379091_9	518766.Rmar_1238	1.482e-67	261.0	COG2222@1|root,COG2222@2|Bacteria,4NIX0@976|Bacteroidetes	976|Bacteroidetes	M	Bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
XH1_k127_379091_1	675812.VHA_003426	8.867e-157	513.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1XSKW@135623|Vibrionales	135623|Vibrionales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
XH1_k127_379091_17	1382303.JPOM01000001_gene2437	1.806e-13	74.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2UC0H@28211|Alphaproteobacteria,2KHC3@204458|Caulobacterales	204458|Caulobacterales	G	TIGRFAM phosphocarrier, HPr family	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
XH1_k127_379091_21	1121918.ARWE01000001_gene1879	4.009e-06	57.0	COG3716@1|root,COG3716@2|Bacteria,1MWTZ@1224|Proteobacteria,42SXR@68525|delta/epsilon subdivisions,2WPQN@28221|Deltaproteobacteria,43SJ5@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PTS system mannose/fructose/sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
XH1_k127_379091_20	1400520.LFAB_14395	2.884e-08	64.0	COG3715@1|root,COG3715@2|Bacteria,1UYP8@1239|Firmicutes,4IQM3@91061|Bacilli,3F5ZV@33958|Lactobacillaceae	91061|Bacilli	G	PTS system sorbose-specific iic component	XK27_08455	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
XH1_k127_379091_12	1379698.RBG1_1C00001G0555	5.887e-31	127.0	COG3444@1|root,COG3444@2|Bacteria,2NQ0P@2323|unclassified Bacteria	2|Bacteria	G	PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794,ko:K19507	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276,M00764	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.6.1.19	-	-	PTSIIB_sorb
XH1_k127_379091_19	1537715.JQFJ01000002_gene2277	4.858e-09	67.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,2K4MZ@204457|Sphingomonadales	204457|Sphingomonadales	G	PTS fructose transporter subunit IIA	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
XH1_k127_379091_7	379066.GAU_1477	1.508e-89	305.0	COG1493@1|root,COG1493@2|Bacteria,1ZSY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
XH1_k127_379091_14	944481.JAFP01000001_gene591	2.475e-27	118.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,2M6K4@213113|Desulfurellales	28221|Deltaproteobacteria	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
XH1_k127_379091_8	1121405.dsmv_0121	2.162e-89	305.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2WIJQ@28221|Deltaproteobacteria,2MIZC@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
XH1_k127_379091_3	379066.GAU_1617	5.754e-106	372.0	COG1508@1|root,COG1508@2|Bacteria,1ZT13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
XH1_k127_379091_4	1379698.RBG1_1C00001G0549	1.229e-101	337.0	COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria	2|Bacteria	S	lipopolysaccharide transport protein B ATP-binding component of ABC superfamily	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
XH1_k127_379091_15	1379698.RBG1_1C00001G0548	5.163e-18	96.0	COG3117@1|root,COG3117@2|Bacteria,2NQ8Q@2323|unclassified Bacteria	2|Bacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K09774,ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
XH1_k127_379091_11	1379698.RBG1_1C00001G0547	4.232e-50	191.0	COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria	2|Bacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
XH1_k127_379091_6	292.DM42_2284	7.906e-90	310.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,1K0GY@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
XH1_k127_379091_18	591001.Acfer_1682	1.36e-12	70.0	COG2877@1|root,COG2877@2|Bacteria,1TR2G@1239|Firmicutes,4H20D@909932|Negativicutes	909932|Negativicutes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
XH1_k127_3806434_4	1278306.KB906920_gene1598	5.546e-19	94.0	COG0621@1|root,COG0621@2|Bacteria,378WY@32066|Fusobacteria	32066|Fusobacteria	J	Uncharacterized protein family UPF0004	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
XH1_k127_3806434_0	1379698.RBG1_1C00001G1225	2.415e-212	678.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4,2.7.11.1	ko:K02945,ko:K03527,ko:K12132	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011	-	-	-	S1
XH1_k127_3806434_1	429009.Adeg_1146	1.308e-70	248.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,42FFX@68295|Thermoanaerobacterales	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
XH1_k127_3806434_2	1449080.JQMV01000003_gene1722	1.07e-28	128.0	COG0204@1|root,COG0204@2|Bacteria,1WJXG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
XH1_k127_3806434_3	1453500.AT05_03035	5.106e-19	98.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1HXBA@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
XH1_k127_380967_2	1117647.M5M_09620	9.355e-05	52.0	2F9BN@1|root,341NM@2|Bacteria,1NYWS@1224|Proteobacteria,1SQE6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
XH1_k127_380967_0	879212.DespoDRAFT_01685	2.174e-39	159.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria,2MJPQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Transmembrane exosortase (Exosortase_EpsH)	epsH	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
XH1_k127_380967_1	1125863.JAFN01000001_gene384	1.231e-22	107.0	COG1269@1|root,COG1269@2|Bacteria,1RF6T@1224|Proteobacteria,42RED@68525|delta/epsilon subdivisions,2WNV7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM EpsI family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
XH1_k127_3839094_0	1121918.ARWE01000001_gene2861	1.363e-09	64.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
XH1_k127_3887369_1	671143.DAMO_0182	3.421e-05	55.0	COG1215@1|root,COG1215@2|Bacteria,2NPYF@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 21	bcsA	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_hydro_26,Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_21,Glycos_transf_2,PilZ
XH1_k127_3887369_0	1380393.JHVP01000008_gene4693	3.262e-21	106.0	COG1807@1|root,COG1807@2|Bacteria,2IB2Q@201174|Actinobacteria,4EW25@85013|Frankiales	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_3917354_7	401526.TcarDRAFT_2376	9.36e-22	108.0	COG0697@1|root,COG0697@2|Bacteria,1V0DI@1239|Firmicutes,4H4CC@909932|Negativicutes	909932|Negativicutes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
XH1_k127_3917354_8	1043493.BBLU01000010_gene216	6.394e-16	84.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
XH1_k127_3917354_3	1235798.C817_01988	7.165e-46	186.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,27V8A@189330|Dorea	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
XH1_k127_3917354_4	635013.TherJR_2043	2.471e-40	152.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,261ZW@186807|Peptococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
XH1_k127_3917354_1	1117379.BABA_23880	2.129e-67	245.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1ZD4X@1386|Bacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
XH1_k127_3917354_9	1448389.BAVQ01000083_gene224	7.269e-13	76.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
XH1_k127_3917354_10	1201288.M900_1562	9.162e-13	72.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2MT7A@213481|Bdellovibrionales,2WQBS@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
XH1_k127_3917354_6	1423758.BN55_03610	1.088e-27	117.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
XH1_k127_3917354_0	632335.Calkr_0953	4.924e-153	497.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,42FGH@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
XH1_k127_3917354_11	391735.Veis_0176	0.0001307	48.0	2AGQ6@1|root,316XW@2|Bacteria,1NIP4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_3917354_5	398767.Glov_1224	4.941e-29	125.0	COG1848@1|root,COG1848@2|Bacteria,1QZUI@1224|Proteobacteria,42XMF@68525|delta/epsilon subdivisions,2WSND@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
XH1_k127_3917354_2	1286171.EAL2_c14650	3.049e-52	193.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,25W6C@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
XH1_k127_3917354_12	999423.HMPREF9161_00527	0.0006148	46.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	909932|Negativicutes	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
XH1_k127_392463_1	237368.SCABRO_00906	1.132e-15	86.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
XH1_k127_392463_0	1379270.AUXF01000003_gene3431	8.521e-48	179.0	COG0308@1|root,COG0308@2|Bacteria,1ZUT0@142182|Gemmatimonadetes	2|Bacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
XH1_k127_4014335_14	1128421.JAGA01000003_gene3053	7.321e-54	210.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,Response_reg,dCache_1
XH1_k127_4014335_18	1157490.EL26_05540	2.885e-48	187.0	COG0384@1|root,COG0384@2|Bacteria,1TRAF@1239|Firmicutes,4HAC5@91061|Bacilli,279RE@186823|Alicyclobacillaceae	91061|Bacilli	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
XH1_k127_4014335_16	498761.HM1_0196	1.378e-52	196.0	COG0642@1|root,COG0732@1|root,COG0784@1|root,COG1352@1|root,COG2201@1|root,COG0732@2|Bacteria,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,MASE3,PAS_9,Response_reg
XH1_k127_4014335_13	1157490.EL26_17020	2.812e-60	235.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,2781E@186823|Alicyclobacillaceae	91061|Bacilli	NT	CHASE3 domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
XH1_k127_4014335_27	1304875.JAFZ01000003_gene537	1.385e-20	99.0	COG0835@1|root,COG0835@2|Bacteria,3TBA6@508458|Synergistetes	508458|Synergistetes	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
XH1_k127_4014335_21	643648.Slip_0981	7.801e-37	144.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,24HH7@186801|Clostridia,42K04@68298|Syntrophomonadaceae	186801|Clostridia	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
XH1_k127_4014335_10	342949.PNA2_1133	9.499e-78	276.0	COG2201@1|root,arCOG02382@2157|Archaea,2XUKR@28890|Euryarchaeota,2433H@183968|Thermococci	183968|Thermococci	N	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
XH1_k127_4014335_9	1183377.Py04_0537	2.061e-90	317.0	COG0643@1|root,arCOG04403@2157|Archaea,2XSUS@28890|Euryarchaeota,243R5@183968|Thermococci	183968|Thermococci	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
XH1_k127_4014335_23	936572.HMPREF1148_0046	6.901e-36	148.0	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,4H25I@909932|Negativicutes	909932|Negativicutes	NT	Chemotaxis protein CheC	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
XH1_k127_4014335_20	632292.Calhy_0597	4.687e-42	157.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,24HJF@186801|Clostridia,42GI7@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM response regulator receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
XH1_k127_4014335_22	379066.GAU_1408	1.053e-36	158.0	COG0457@1|root,COG0457@2|Bacteria,1ZSS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
XH1_k127_4014335_24	1379270.AUXF01000005_gene674	5.218e-26	122.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
XH1_k127_4014335_5	234267.Acid_1201	1.467e-172	565.0	COG3591@1|root,COG3591@2|Bacteria,3Y2TU@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
XH1_k127_4014335_17	1265505.ATUG01000002_gene1979	8.87e-52	194.0	COG0697@1|root,COG0697@2|Bacteria,1Q9JX@1224|Proteobacteria,434FQ@68525|delta/epsilon subdivisions,2WYT5@28221|Deltaproteobacteria,2MN71@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
XH1_k127_4014335_25	349521.HCH_04827	1.385e-23	116.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,1RZTX@1236|Gammaproteobacteria,1XMSW@135619|Oceanospirillales	135619|Oceanospirillales	D	ATPase of the PP-loop superfamily implicated in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4014335_7	190650.CC_0796	3.944e-150	498.0	COG4948@1|root,COG4948@2|Bacteria,1QVFR@1224|Proteobacteria,2U0VN@28211|Alphaproteobacteria,2KHK8@204458|Caulobacterales	204458|Caulobacterales	M	Alpha-glucosidase	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
XH1_k127_4014335_6	671143.DAMO_0012	3.753e-152	501.0	COG1966@1|root,COG1966@2|Bacteria,2NNP2@2323|unclassified Bacteria	2|Bacteria	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
XH1_k127_4014335_2	1191523.MROS_1593	1.061e-219	734.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06889,ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,Peptidase_S9
XH1_k127_4014335_19	1189612.A33Q_1476	1.227e-42	180.0	COG0671@1|root,COG0671@2|Bacteria,4NR78@976|Bacteroidetes,47QF8@768503|Cytophagia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
XH1_k127_4014335_1	1121930.AQXG01000001_gene1202	4.439e-295	948.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
XH1_k127_4014335_0	1121930.AQXG01000001_gene1203	0.0	1240.0	COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
XH1_k127_4014335_8	1121104.AQXH01000001_gene1411	2.384e-92	315.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
XH1_k127_4014335_4	742725.HMPREF9450_02241	5.1e-191	613.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,2FNB6@200643|Bacteroidia,22V19@171550|Rikenellaceae	976|Bacteroidetes	P	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
XH1_k127_4014335_12	323259.Mhun_2196	8.506e-66	236.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,2NAKT@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_4014335_11	653733.Selin_0905	3.197e-71	263.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
XH1_k127_4014335_3	247490.KSU1_C1645	9.556e-211	668.0	COG0058@1|root,COG0058@2|Bacteria,2IY0J@203682|Planctomycetes	203682|Planctomycetes	G	COG0058 Glucan phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphorylase,YHS
XH1_k127_4014335_26	326427.Cagg_0564	1.474e-23	116.0	COG1287@1|root,COG1287@2|Bacteria,2G9P1@200795|Chloroflexi,375X4@32061|Chloroflexia	32061|Chloroflexia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_4014335_28	1454004.AW11_02184	2.141e-15	86.0	2BDT3@1|root,327GV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_406712_3	562970.Btus_0737	2.911e-72	255.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,2788X@186823|Alicyclobacillaceae	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
XH1_k127_406712_1	984262.SGRA_2599	1.615e-91	314.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1IQDT@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
XH1_k127_406712_2	429009.Adeg_1474	3.659e-88	298.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,42EQD@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
XH1_k127_406712_0	1385512.N784_06835	3.613e-98	325.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,2Y8N1@289201|Pontibacillus	91061|Bacilli	S	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
XH1_k127_4076554_11	945713.IALB_1535	4.354e-50	189.0	COG0811@1|root,COG0811@2|Bacteria	2|Bacteria	U	bacteriocin transport	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
XH1_k127_4076554_19	880073.Calab_2425	2.817e-19	92.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
XH1_k127_4076554_21	880073.Calab_2426	7.002e-18	89.0	COG0848@1|root,COG0848@2|Bacteria,2NRQH@2323|unclassified Bacteria	2|Bacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
XH1_k127_4076554_17	880073.Calab_1495	1.86e-22	105.0	COG0810@1|root,COG0810@2|Bacteria,2NQ1D@2323|unclassified Bacteria	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
XH1_k127_4076554_14	1392502.JNIO01000002_gene605	1.006e-29	138.0	COG1538@1|root,COG1538@2|Bacteria,1TQ0W@1239|Firmicutes,4H3MR@909932|Negativicutes	909932|Negativicutes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
XH1_k127_4076554_4	880073.Calab_1156	1.509e-93	316.0	COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_4076554_8	1379698.RBG1_1C00001G1364	2.947e-80	284.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
XH1_k127_4076554_6	1379698.RBG1_1C00001G1366	1.714e-87	304.0	COG0577@1|root,COG0577@2|Bacteria,2NQMU@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
XH1_k127_4076554_7	1047013.AQSP01000140_gene2536	3.166e-82	288.0	COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria	2|Bacteria	V	COGs COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
XH1_k127_4076554_18	945713.IALB_0624	4.589e-20	104.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6,DUF4309,DUF5301
XH1_k127_4076554_2	861299.J421_2541	5.775e-102	372.0	COG4166@1|root,COG4166@2|Bacteria,1ZSMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
XH1_k127_4076554_3	861299.J421_2540	5.756e-99	334.0	COG0601@1|root,COG0601@2|Bacteria,1ZSXJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
XH1_k127_4076554_9	883.DvMF_0921	6.355e-69	257.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2M8HR@213115|Desulfovibrionales	28221|Deltaproteobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
XH1_k127_4076554_13	693979.Bache_1925	2.829e-46	180.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,2FMNQ@200643|Bacteroidia,4AP9P@815|Bacteroidaceae	976|Bacteroidetes	M	NlpC P60 family protein	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
XH1_k127_4076554_20	880073.Calab_0119	1.088e-18	99.0	2F9BU@1|root,341NU@2|Bacteria,2NR9C@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4076554_15	518766.Rmar_1300	1.578e-24	117.0	COG0705@1|root,COG0705@2|Bacteria,4PFKF@976|Bacteroidetes,1FK7W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
XH1_k127_4076554_12	646529.Desaci_4308	4.87e-49	183.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,25ZZS@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
XH1_k127_4076554_0	1379698.RBG1_1C00001G1860	6.152e-146	469.0	COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria	2|Bacteria	D	MreB/Mbl protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
XH1_k127_4076554_16	1379698.RBG1_1C00001G1001	4.478e-24	117.0	COG1792@1|root,COG1792@2|Bacteria,2NPNX@2323|unclassified Bacteria	2|Bacteria	M	Cell shape-determining protein MreC	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
XH1_k127_4076554_22	1379698.RBG1_1C00001G1002	0.0001325	51.0	29494@1|root,2ZRPB@2|Bacteria	2|Bacteria	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
XH1_k127_4076554_1	1379698.RBG1_1C00001G1003	2.449e-114	392.0	COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding protein 2	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
XH1_k127_4076554_5	1379698.RBG1_1C00001G1004	1.476e-92	318.0	COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria	2|Bacteria	D	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
XH1_k127_4076554_10	1379698.RBG1_1C00001G1006	4.803e-56	205.0	COG0682@1|root,COG0682@2|Bacteria,2NPK2@2323|unclassified Bacteria	2|Bacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
XH1_k127_4088307_12	264462.Bd2994	8.185e-14	71.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2MSMP@213481|Bdellovibrionales,2WJ2B@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
XH1_k127_4088307_11	1123325.JHUV01000003_gene1570	8.292e-18	85.0	COG0267@1|root,COG0267@2|Bacteria,2G493@200783|Aquificae	200783|Aquificae	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
XH1_k127_4088307_13	1379698.RBG1_1C00001G1611	4.287e-07	53.0	COG0690@1|root,COG0690@2|Bacteria,2NQ1C@2323|unclassified Bacteria	2|Bacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
XH1_k127_4088307_6	644966.Tmar_2308	6.955e-54	196.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3WCHU@538999|Clostridiales incertae sedis	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
XH1_k127_4088307_7	866775.HMPREF9243_0394	3.861e-53	191.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,27DYK@186827|Aerococcaceae	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
XH1_k127_4088307_3	1121121.KB894322_gene391	1.593e-88	298.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,26SRZ@186822|Paenibacillaceae	91061|Bacilli	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
XH1_k127_4088307_9	398512.JQKC01000005_gene5349	8.676e-37	146.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3WIH7@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
XH1_k127_4088307_8	521460.Athe_1528	1.642e-37	147.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,42GKP@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
XH1_k127_4088307_1	1379698.RBG1_1C00001G1605	0.0	1571.0	COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
XH1_k127_4088307_0	1379698.RBG1_1C00001G1604	0.0	1921.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
XH1_k127_4088307_4	401526.TcarDRAFT_0993	2.794e-60	210.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4H4CG@909932|Negativicutes	909932|Negativicutes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
XH1_k127_4088307_5	338963.Pcar_0697	1.598e-58	206.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,43U5Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
XH1_k127_4088307_2	868864.Dester_0191	1.915e-285	893.0	COG0480@1|root,COG0480@2|Bacteria,2G3NW@200783|Aquificae	200783|Aquificae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
XH1_k127_4088307_10	1499967.BAYZ01000113_gene2944	5.023e-18	83.0	COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria	2|Bacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
XH1_k127_41132_5	926561.KB900618_gene374	2.798e-26	117.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,3WBBW@53433|Halanaerobiales	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15760	Porphobil_deam,Porphobil_deamC
XH1_k127_41132_1	224324.aq_298	1.061e-133	449.0	COG0172@1|root,COG0172@2|Bacteria,2G3RF@200783|Aquificae	200783|Aquificae	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
XH1_k127_41132_2	518766.Rmar_1450	1.033e-81	288.0	COG0642@1|root,COG2205@2|Bacteria,4PKGE@976|Bacteroidetes,1FIRF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
XH1_k127_41132_0	1379698.RBG1_1C00001G1545	4.058e-169	565.0	COG0745@1|root,COG0745@2|Bacteria,2NNXK@2323|unclassified Bacteria	2|Bacteria	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
XH1_k127_41132_6	1514668.JOOA01000002_gene3028	1.146e-24	109.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3WK7G@541000|Ruminococcaceae	186801|Clostridia	S	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
XH1_k127_41132_4	443144.GM21_1493	6.922e-27	123.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,43UMP@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
XH1_k127_41132_3	644966.Tmar_0268	7.724e-28	127.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WDCE@538999|Clostridiales incertae sedis	186801|Clostridia	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
XH1_k127_41132_7	448385.sce5862	2.006e-17	87.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P3C@68525|delta/epsilon subdivisions,2WJW1@28221|Deltaproteobacteria,2YUUB@29|Myxococcales	28221|Deltaproteobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
XH1_k127_4185510_2	566466.NOR53_2744	2.669e-13	75.0	COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria,1J9V3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Bacterial DNA-binding protein	VL23_14575	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
XH1_k127_4185510_1	1408473.JHXO01000001_gene2146	1.316e-85	307.0	COG1453@1|root,COG1453@2|Bacteria,4NJU2@976|Bacteroidetes,2G2UD@200643|Bacteroidia	976|Bacteroidetes	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
XH1_k127_4185510_0	378806.STAUR_1666	6.545e-152	488.0	2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,42Y78@68525|delta/epsilon subdivisions,2X3CW@28221|Deltaproteobacteria,2YUS0@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
XH1_k127_4185510_3	1444310.JANV01000056_gene425	1.86e-06	57.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,1ZCW1@1386|Bacillus	91061|Bacilli	CO	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c	resA	GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
XH1_k127_4289334_1	1125863.JAFN01000001_gene808	1.7e-114	377.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
XH1_k127_4289334_4	43179.ENSSTOP00000018283	4.359e-10	68.0	COG0456@1|root,KOG3139@2759|Eukaryota,39YBU@33154|Opisthokonta,3BR0I@33208|Metazoa,3D7AP@33213|Bilateria,48QZI@7711|Chordata,49MJG@7742|Vertebrata,3JNH8@40674|Mammalia,35UC4@314146|Euarchontoglires,4QA26@9989|Rodentia	33208|Metazoa	S	Acetyltransferase (GNAT) domain	NAT8B	GO:0001702,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0007162,GO:0007275,GO:0007369,GO:0008150,GO:0009653,GO:0009790,GO:0012505,GO:0030155,GO:0032501,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048598,GO:0048856,GO:0050789,GO:0050794,GO:0065007	2.3.1.80	ko:K20838	ko00480,map00480	-	R04950	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
XH1_k127_4289334_0	65093.PCC7418_2137	1.077e-140	459.0	COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.agp,iSbBS512_1146.agp	NTP_transferase
XH1_k127_4289334_3	237368.SCABRO_00905	1.193e-95	330.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
XH1_k127_4289334_2	237368.SCABRO_00906	1.504e-97	334.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
XH1_k127_4310024_0	880073.Calab_0681	8.462e-167	554.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	pkn5	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1
XH1_k127_4310024_2	518766.Rmar_0357	2.897e-08	67.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
XH1_k127_4310024_3	1379698.RBG1_1C00001G0991	0.0003616	56.0	COG2911@1|root,COG2931@1|root,COG4447@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4447@2|Bacteria,2NR5X@2323|unclassified Bacteria	2|Bacteria	Q	FlgD Ig-like domain	-	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_3,DUF1735,Laminin_G_3
XH1_k127_4310024_1	471853.Bcav_2782	7.009e-25	125.0	COG1404@1|root,COG2911@1|root,COG4932@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,2GYXK@201174|Actinobacteria	201174|Actinobacteria	M	Invasin, domain 3	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Invasin_D3
XH1_k127_4310278_17	264462.Bd2994	8.185e-14	71.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2MSMP@213481|Bdellovibrionales,2WJ2B@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
XH1_k127_4310278_9	880073.Calab_2125	1.103e-40	154.0	COG0051@1|root,COG0051@2|Bacteria,2NPJY@2323|unclassified Bacteria	2|Bacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
XH1_k127_4310278_5	1304284.L21TH_0892	4.219e-59	212.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,36DP8@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
XH1_k127_4310278_6	246194.CHY_2308	3.442e-53	194.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,42ERX@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
XH1_k127_4310278_16	667014.Thein_1465	3.799e-20	100.0	COG0089@1|root,COG0089@2|Bacteria,2GHYR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
XH1_k127_4310278_0	1379281.AVAG01000008_gene1363	4.045e-122	398.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,2M8B7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
XH1_k127_4310278_10	1379698.RBG1_1C00001G1592	9.548e-39	147.0	COG0185@1|root,COG0185@2|Bacteria,2NPIV@2323|unclassified Bacteria	2|Bacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
XH1_k127_4310278_12	1435356.Y013_08565	1.937e-26	112.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4G0FM@85025|Nocardiaceae	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
XH1_k127_4310278_1	880073.Calab_2132	2.452e-80	276.0	COG0092@1|root,COG0092@2|Bacteria,2NP6J@2323|unclassified Bacteria	2|Bacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
XH1_k127_4310278_4	497965.Cyan7822_5057	9.216e-60	209.0	COG0197@1|root,COG0197@2|Bacteria,1G55B@1117|Cyanobacteria,3KHQQ@43988|Cyanothece	1117|Cyanobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
XH1_k127_4310278_18	1511.CLOST_2190	5.195e-11	67.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,25RVP@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
XH1_k127_4310278_13	1408322.JHYK01000004_gene871	4.825e-25	106.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,27NW5@186928|unclassified Lachnospiraceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
XH1_k127_4310278_7	525909.Afer_0408	6.442e-52	185.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CMZN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
XH1_k127_4310278_11	706587.Desti_5273	1.571e-30	123.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2WQ2G@28221|Deltaproteobacteria,2MS2M@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
XH1_k127_4310278_2	429009.Adeg_1512	2.545e-79	268.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,42F2S@68295|Thermoanaerobacterales	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
XH1_k127_4310278_15	555088.DealDRAFT_1510	1.456e-23	103.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,42K5P@68298|Syntrophomonadaceae	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
XH1_k127_4310278_8	289376.THEYE_A1432	7.675e-43	163.0	COG0096@1|root,COG0096@2|Bacteria,3J0SJ@40117|Nitrospirae	40117|Nitrospirae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
XH1_k127_4310278_3	401526.TcarDRAFT_1012	1.228e-64	226.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4H3Z2@909932|Negativicutes	909932|Negativicutes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
XH1_k127_4310278_14	639282.DEFDS_1756	1.252e-24	110.0	COG0256@1|root,COG0256@2|Bacteria,2GFQQ@200930|Deferribacteres	200930|Deferribacteres	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
XH1_k127_4326892_3	861299.J421_2976	3.256e-62	234.0	COG1657@1|root,COG1657@2|Bacteria,1ZSPV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
XH1_k127_4326892_2	243231.GSU0812	1.658e-68	267.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43TNJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
XH1_k127_4326892_4	1541065.JRFE01000022_gene3986	5.382e-12	74.0	COG2839@1|root,COG2839@2|Bacteria,1G66N@1117|Cyanobacteria,3VJKZ@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
XH1_k127_4326892_1	1232410.KI421418_gene2299	1.814e-75	267.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43RZY@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	SecD/SecF GG Motif	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
XH1_k127_4326892_0	933262.AXAM01000020_gene23	9.161e-85	294.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MHS8@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
XH1_k127_4354939_3	339670.Bamb_0152	2.566e-15	88.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,1K03X@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5,Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
XH1_k127_4354939_2	204669.Acid345_4329	6.624e-21	106.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,GGDEF,Trans_reg_C,Yop-YscD_cpl
XH1_k127_4354939_1	1499967.BAYZ01000167_gene6734	7.708e-46	191.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
XH1_k127_4354939_0	1379698.RBG1_1C00001G1613	1.033e-65	240.0	COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria	2|Bacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,PEGA,Pkinase
XH1_k127_4428333_1	643648.Slip_0837	2.471e-66	234.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,42JUY@68298|Syntrophomonadaceae	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
XH1_k127_4428333_2	1449335.JQLG01000004_gene1223	5.851e-21	104.0	COG2076@1|root,COG2076@2|Bacteria,1TRP3@1239|Firmicutes,4HCX9@91061|Bacilli,27FGP@186828|Carnobacteriaceae	91061|Bacilli	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
XH1_k127_4428333_0	880073.Calab_2784	2.431e-181	583.0	COG1164@1|root,COG1164@2|Bacteria,2NQ8K@2323|unclassified Bacteria	2|Bacteria	E	Oligoendopeptidase f	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2,Peptidase_M3
XH1_k127_4445159_5	385682.AFSL01000073_gene1404	9.511e-92	308.0	COG4690@1|root,COG4690@2|Bacteria,4NE03@976|Bacteroidetes,2FPSX@200643|Bacteroidia,3XJ9B@558415|Marinilabiliaceae	976|Bacteroidetes	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
XH1_k127_4445159_12	1509405.GV67_23505	1.898e-15	91.0	COG2244@1|root,COG2244@2|Bacteria,1MWKV@1224|Proteobacteria,2TTYS@28211|Alphaproteobacteria,4B9SC@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	MA20_18165	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
XH1_k127_4445159_0	1047013.AQSP01000142_gene241	2.513e-217	682.0	COG0252@1|root,COG0252@2|Bacteria,2NPMK@2323|unclassified Bacteria	2|Bacteria	EJ	Asparaginase	ansA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
XH1_k127_4445159_1	1047013.AQSP01000142_gene242	1.645e-152	505.0	COG2511@1|root,COG2511@2|Bacteria	2|Bacteria	J	GatB/GatE catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GatB_N
XH1_k127_4445159_2	1321778.HMPREF1982_03829	1.366e-137	454.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,2683F@186813|unclassified Clostridiales	186801|Clostridia	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
XH1_k127_4445159_3	1168034.FH5T_20550	1.508e-132	435.0	COG2223@1|root,COG2223@2|Bacteria,4NHX9@976|Bacteroidetes,2FZ04@200643|Bacteroidia	976|Bacteroidetes	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
XH1_k127_4445159_6	1128421.JAGA01000002_gene938	6.175e-69	239.0	COG0302@1|root,COG0302@2|Bacteria,2NPAT@2323|unclassified Bacteria	2|Bacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
XH1_k127_4445159_7	485913.Krac_7650	1.502e-54	201.0	COG0231@1|root,COG0231@2|Bacteria,2G6P4@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
XH1_k127_4445159_4	880073.Calab_0924	2.443e-95	345.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
XH1_k127_4445159_8	945713.IALB_2905	3.202e-48	187.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4445159_10	304371.MCP_2388	4.244e-44	178.0	COG0535@1|root,arCOG00938@2157|Archaea,2Y8D0@28890|Euryarchaeota,2NAAK@224756|Methanomicrobia	224756|Methanomicrobia	S	radical SAM domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
XH1_k127_4445159_9	484770.UFO1_4220	3.805e-45	177.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
XH1_k127_4446640_0	1379698.RBG1_1C00001G0864	2.425e-99	362.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744,ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA,OstA_C
XH1_k127_4446640_2	1356854.N007_13710	2.196e-22	99.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKK7@91061|Bacilli,27A5Y@186823|Alicyclobacillaceae	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
XH1_k127_4446640_1	1131269.AQVV01000002_gene1187	7.985e-35	148.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	mnuA	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
XH1_k127_4446640_3	595460.RRSWK_05435	3.407e-18	96.0	2EYTK@1|root,33S0U@2|Bacteria,2IYA9@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1
XH1_k127_4447905_0	1379698.RBG1_1C00001G0719	3.034e-141	460.0	COG0612@1|root,COG0612@2|Bacteria,2NP50@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
XH1_k127_4447905_1	1379698.RBG1_1C00001G0718	2.338e-96	332.0	COG0612@1|root,COG0612@2|Bacteria,2NPE5@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
XH1_k127_4447905_2	880073.Calab_2081	1.46e-10	62.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
XH1_k127_4475824_0	1379698.RBG1_1C00001G1789	6.182e-93	332.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
XH1_k127_4475824_2	517418.Ctha_2165	1.649e-38	158.0	COG2067@1|root,COG2067@2|Bacteria,1FEW1@1090|Chlorobi	1090|Chlorobi	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4475824_1	1379698.RBG1_1C00001G1787	4.337e-48	199.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	DUF1863,PQQ_2
XH1_k127_4475824_3	1379698.RBG1_1C00001G1786	3.067e-11	76.0	2CUTJ@1|root,32SW3@2|Bacteria,2NRD1@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4475824_4	1379698.RBG1_1C00001G1785	3.421e-09	70.0	2EAWV@1|root,334Y2@2|Bacteria,2NRSF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4479600_16	555079.Toce_1203	1.05e-40	154.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia,42F7D@68295|Thermoanaerobacterales	186801|Clostridia	C	Best Blastp hit gi 6685602 sp Q57957 KORB_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORB (2-KETOGLUTARATE OXIDOREDUCTASE BETA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT) gi 2129229 pir A64367 pyruvate synthase (EC 1.2.7.1) beta chain - Methanococcus jannaschii gi 1591241 gb AAB98531.1 '(U67503) 2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB) Methanococcus jannaschii ', score	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
XH1_k127_4479600_22	1195236.CTER_3761	3.123e-19	94.0	COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,24I53@186801|Clostridia,3WJ35@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases gamma subunit	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
XH1_k127_4479600_8	518766.Rmar_0066	6.789e-70	254.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1FJ0W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
XH1_k127_4479600_12	596151.DesfrDRAFT_0781	3.506e-49	185.0	COG1595@1|root,COG1595@2|Bacteria,1N413@1224|Proteobacteria,42SGS@68525|delta/epsilon subdivisions,2WPQ9@28221|Deltaproteobacteria,2MB1H@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_4479600_21	1047013.AQSP01000095_gene2301	9.756e-25	115.0	2DS9E@1|root,32VU1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4479600_9	1121405.dsmv_0026	5.281e-62	235.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2MJZR@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
XH1_k127_4479600_4	1499967.BAYZ01000149_gene6774	4.55e-113	410.0	COG0665@1|root,COG0665@2|Bacteria,2NP0X@2323|unclassified Bacteria	2|Bacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
XH1_k127_4479600_3	1047013.AQSP01000126_gene2731	2.978e-235	747.0	COG0446@1|root,COG1142@1|root,COG1251@1|root,COG2080@1|root,COG0446@2|Bacteria,COG1142@2|Bacteria,COG1251@2|Bacteria,COG2080@2|Bacteria,2NP2E@2323|unclassified Bacteria	2|Bacteria	C	FAD dependent oxidoreductase	-	-	1.12.5.1,1.2.5.3,1.3.99.16,1.7.1.15	ko:K00205,ko:K00362,ko:K02573,ko:K03518,ko:K05927,ko:K07302	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00530,M00567	R00787,R03015,R08060,R11168,R11743	RC00176,RC00197,RC00323,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2,Fer2_4,Fer2_BFD,Fer4,Fer4_20,Fer4_7,GXGXG,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
XH1_k127_4479600_13	335543.Sfum_1176	3.968e-49	190.0	COG0247@1|root,COG0247@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria,2MR23@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
XH1_k127_4479600_6	1089553.Tph_c08060	6.294e-82	306.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42EUY@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.10,1.17.1.9,1.97.1.9	ko:K00123,ko:K12527,ko:K15022	ko00450,ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00450,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519,R07229	RC02420,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Pyr_redox_2,Pyr_redox_3
XH1_k127_4479600_14	552811.Dehly_0623	5.922e-49	189.0	COG3383@1|root,COG3383@2|Bacteria,2GAS8@200795|Chloroflexi,34D7W@301297|Dehalococcoidia	301297|Dehalococcoidia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4
XH1_k127_4479600_17	429009.Adeg_0158	3.301e-36	144.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24I29@186801|Clostridia,42ICW@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
XH1_k127_4479600_1	311424.DhcVS_635	9.558e-250	794.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi,34D48@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
XH1_k127_4479600_2	552811.Dehly_0355	4.786e-239	755.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,2G78Z@200795|Chloroflexi,34CMK@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Conserved carboxylase domain	oadA	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
XH1_k127_4479600_26	596151.DesfrDRAFT_2130	2.124e-12	77.0	COG3852@1|root,COG4936@1|root,COG5000@1|root,COG3852@2|Bacteria,COG4936@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42Y7R@68525|delta/epsilon subdivisions,2WUPP@28221|Deltaproteobacteria,2MHD5@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
XH1_k127_4479600_23	926550.CLDAP_00860	5.703e-18	98.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
XH1_k127_4479600_20	1121468.AUBR01000006_gene387	6.26e-30	138.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,42F3M@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
XH1_k127_4479600_5	479434.Sthe_1770	1.402e-105	353.0	COG1087@1|root,COG1087@2|Bacteria,2G80W@200795|Chloroflexi,27Y6Y@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
XH1_k127_4479600_0	861299.J421_3780	5.2e-280	891.0	COG0178@1|root,COG0178@2|Bacteria,1ZT1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
XH1_k127_4479600_11	1121430.JMLG01000004_gene915	8.802e-60	219.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,2613S@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM MazG family protein	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
XH1_k127_4479600_10	1278073.MYSTI_03700	1.103e-60	232.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,OmpA,Phenol_MetA_deg,TSP_3
XH1_k127_4479600_24	1379698.RBG1_1C00001G0404	1.828e-17	87.0	2EAFJ@1|root,334IY@2|Bacteria,2NRZR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
XH1_k127_4479600_25	1121289.JHVL01000011_gene1408	2.338e-15	85.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia,36F4A@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
XH1_k127_4479600_19	1449126.JQKL01000019_gene3245	1.67e-30	128.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia	186801|Clostridia	K	domain protein	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
XH1_k127_4479600_15	1125863.JAFN01000001_gene536	7.86e-46	179.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2WQD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
XH1_k127_4479600_7	861299.J421_2641	3.036e-72	268.0	COG1519@1|root,COG1519@2|Bacteria,1ZSXB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
XH1_k127_4479600_18	537970.HCAN_0639	7.891e-34	151.0	COG0535@1|root,COG0535@2|Bacteria,1PEYS@1224|Proteobacteria,42SNS@68525|delta/epsilon subdivisions,2YQGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
XH1_k127_4479600_28	754027.HMPREF9554_02961	0.0009344	46.0	COG0009@1|root,COG0009@2|Bacteria,2J7KX@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the SUA5 family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
XH1_k127_4499991_7	944479.JQLX01000010_gene518	0.0002845	49.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2M703@213113|Desulfurellales	28221|Deltaproteobacteria	E	Dihydrodipicolinate reductase, C-terminus	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
XH1_k127_4499991_1	289376.THEYE_A0933	5.096e-94	329.0	COG0329@1|root,COG0329@2|Bacteria,3J0CF@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
XH1_k127_4499991_2	742740.HMPREF9474_03617	1.384e-84	293.0	COG2515@1|root,COG2515@2|Bacteria,1UDCW@1239|Firmicutes,24BXZ@186801|Clostridia,220EC@1506553|Lachnoclostridium	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
XH1_k127_4499991_5	1449058.JQKT01000007_gene960	3.738e-07	56.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4FPP9@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
XH1_k127_4499991_4	63737.Npun_F6249	9.236e-35	142.0	COG3118@1|root,COG3118@2|Bacteria,1GDW5@1117|Cyanobacteria,1HNJ5@1161|Nostocales	1117|Cyanobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
XH1_k127_4499991_6	1255043.TVNIR_3543	1.027e-05	58.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria,1WXJP@135613|Chromatiales	135613|Chromatiales	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_4499991_3	706587.Desti_1348	1.05e-40	168.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,42PY0@68525|delta/epsilon subdivisions,2WJ2Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
XH1_k127_4499991_0	224324.aq_542	1.274e-120	399.0	COG3635@1|root,COG3635@2|Bacteria	2|Bacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
XH1_k127_4501694_3	1121920.AUAU01000006_gene293	4.602e-102	344.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y3BP@57723|Acidobacteria	57723|Acidobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
XH1_k127_4501694_7	880073.Calab_0913	1.209e-20	108.0	COG1523@1|root,COG1523@2|Bacteria	2|Bacteria	G	belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
XH1_k127_4501694_4	247490.KSU1_C0449	1.17e-88	325.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
XH1_k127_4501694_1	443143.GM18_2052	4.896e-198	634.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA-1	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
XH1_k127_4501694_5	1121405.dsmv_2840	9.369e-56	207.0	COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,42SK4@68525|delta/epsilon subdivisions,2WPI8@28221|Deltaproteobacteria,2MNKA@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	iorB-1	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
XH1_k127_4501694_0	1047013.AQSP01000075_gene1424	0.0	1431.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
XH1_k127_4501694_2	215803.DB30_4900	2.364e-102	378.0	COG1680@1|root,COG1680@2|Bacteria,1PEI7@1224|Proteobacteria,43DSW@68525|delta/epsilon subdivisions,2X8V3@28221|Deltaproteobacteria,2Z0DE@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
XH1_k127_4501694_8	1123508.JH636443_gene4706	5.435e-19	88.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
XH1_k127_4501694_10	1265505.ATUG01000001_gene3003	5.043e-10	68.0	COG0759@1|root,COG0759@2|Bacteria,1QA6X@1224|Proteobacteria,42VEQ@68525|delta/epsilon subdivisions,2WR96@28221|Deltaproteobacteria,2MKX2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Haemolytic	-	-	-	-	-	-	-	-	-	-	-	-	Haemolytic
XH1_k127_450989_2	203119.Cthe_1805	2.972e-84	290.0	COG2199@1|root,COG3706@2|Bacteria,1UHZ8@1239|Firmicutes,25E7W@186801|Clostridia,3WGN1@541000|Ruminococcaceae	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
XH1_k127_450989_6	1410620.SHLA_68c000160	7.355e-23	109.0	COG0642@1|root,COG2205@2|Bacteria,1RCSX@1224|Proteobacteria,2U5U3@28211|Alphaproteobacteria,4B9U2@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	divJ	-	2.7.13.3	ko:K11357	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
XH1_k127_450989_1	1232410.KI421418_gene2385	4.417e-87	321.0	COG0642@1|root,COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2206@2|Bacteria,1NSAV@1224|Proteobacteria,42Z68@68525|delta/epsilon subdivisions,2WURV@28221|Deltaproteobacteria,43U68@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD_5,HisKA
XH1_k127_450989_3	272123.Anacy_4264	9.094e-44	184.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG2203@1|root,COG2204@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1G027@1117|Cyanobacteria,1HKPC@1161|Nostocales	1117|Cyanobacteria	T	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,Trans_reg_C
XH1_k127_450989_4	944479.JQLX01000013_gene1442	2.542e-37	163.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HD,HD_5
XH1_k127_450989_5	555079.Toce_0967	5.661e-35	144.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,42JDU@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
XH1_k127_450989_0	338966.Ppro_2612	1.046e-151	500.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,43U9D@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
XH1_k127_4538160_13	459349.CLOAM1816	3.275e-30	124.0	COG1917@1|root,COG1917@2|Bacteria,2NQ91@2323|unclassified Bacteria	2|Bacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
XH1_k127_4538160_17	419665.Maeo_0419	9.149e-16	88.0	COG0535@1|root,arCOG00938@2157|Archaea,2Y12G@28890|Euryarchaeota,23R8Z@183939|Methanococci	183939|Methanococci	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
XH1_k127_4538160_15	429009.Adeg_0069	1.074e-23	109.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
XH1_k127_4538160_3	1267535.KB906767_gene248	7.94e-129	419.0	COG0115@1|root,COG0115@2|Bacteria,3Y32X@57723|Acidobacteria,2JI58@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
XH1_k127_4538160_12	1196324.A374_18469	1.7e-45	172.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,4HGXD@91061|Bacilli	91061|Bacilli	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
XH1_k127_4538160_0	639282.DEFDS_0485	1.844e-176	561.0	COG0112@1|root,COG0112@2|Bacteria,2GERI@200930|Deferribacteres	200930|Deferribacteres	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
XH1_k127_4538160_9	316067.Geob_2673	2.229e-62	218.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,43U1G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM CMP dCMP deaminase zinc-binding	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
XH1_k127_4538160_10	203119.Cthe_0450	2.924e-51	185.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3WJ07@541000|Ruminococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
XH1_k127_4538160_11	1379698.RBG1_1C00001G1447	1.15e-46	177.0	COG0805@1|root,COG0805@2|Bacteria,2NPGB@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
XH1_k127_4538160_7	1242864.D187_002120	4.667e-87	305.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4538160_8	648996.Theam_0081	1.131e-63	232.0	COG0142@1|root,COG0142@2|Bacteria,2G3VQ@200783|Aquificae	200783|Aquificae	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
XH1_k127_4538160_5	1121430.JMLG01000009_gene475	6.127e-107	360.0	COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,248K9@186801|Clostridia,2617J@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
XH1_k127_4538160_14	517418.Ctha_0064	4.738e-28	128.0	COG0799@1|root,COG0799@2|Bacteria,1FE3F@1090|Chlorobi	1090|Chlorobi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
XH1_k127_4538160_1	867903.ThesuDRAFT_00509	2.929e-149	493.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,3WCU1@538999|Clostridiales incertae sedis	186801|Clostridia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
XH1_k127_4538160_6	290397.Adeh_1632	3.741e-101	339.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
XH1_k127_4538160_4	1131730.BAVI_05739	1.832e-117	391.0	COG4671@1|root,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
XH1_k127_4538160_16	517418.Ctha_2076	2.882e-19	102.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1FF5N@1090|Chlorobi	1090|Chlorobi	U	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4538160_2	335543.Sfum_1836	3.733e-137	444.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,42PWI@68525|delta/epsilon subdivisions,2WKFE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	TIGRFAM pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
XH1_k127_454306_16	401526.TcarDRAFT_1987	1.047e-15	80.0	COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes,4H37A@909932|Negativicutes	909932|Negativicutes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
XH1_k127_454306_15	1379698.RBG1_1C00001G1780	3.119e-16	87.0	COG0826@1|root,COG0826@2|Bacteria,2NS1M@2323|unclassified Bacteria	2|Bacteria	O	peptidase U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
XH1_k127_454306_14	264462.Bd1717	1.653e-16	81.0	COG2119@1|root,COG2119@2|Bacteria,1PP1W@1224|Proteobacteria,42XF8@68525|delta/epsilon subdivisions,2MUB4@213481|Bdellovibrionales,2WTC8@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
XH1_k127_454306_9	1125863.JAFN01000001_gene603	5.096e-35	147.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42N6V@68525|delta/epsilon subdivisions,2WIQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	JM	PFAM Aminoglycoside phosphotransferase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH,NTP_transferase
XH1_k127_454306_10	1403819.BATR01000005_gene153	1.299e-30	137.0	COG1208@1|root,COG1208@2|Bacteria,46SJP@74201|Verrucomicrobia,2IU9T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
XH1_k127_454306_3	880073.Calab_1758	2.213e-116	387.0	COG3876@1|root,COG3876@2|Bacteria,2NNRQ@2323|unclassified Bacteria	2|Bacteria	S	PFAM Uncharacterised conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
XH1_k127_454306_11	269799.Gmet_2743	1.296e-29	136.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6,Peptidase_S8,TIG
XH1_k127_454306_6	1123371.ATXH01000006_gene861	5.251e-85	301.0	COG0747@1|root,COG0747@2|Bacteria,2GHG2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
XH1_k127_454306_12	1540221.JQNI01000002_gene1241	5.258e-28	118.0	COG1963@1|root,COG1963@2|Bacteria,1WJV3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Acid phosphatase vanadium-dependent haloperoxidase related	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
XH1_k127_454306_8	345219.Bcoa_1292	1.837e-47	184.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1ZBXG@1386|Bacillus	91061|Bacilli	D	COG1192 ATPases involved in chromosome partitioning	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
XH1_k127_454306_18	1089550.ATTH01000001_gene1005	3.603e-08	66.0	COG1404@1|root,COG3591@1|root,COG4932@1|root,COG1404@2|Bacteria,COG3591@2|Bacteria,COG4932@2|Bacteria,4NG2K@976|Bacteroidetes,1FJTD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EO	Trypsin-like serine protease	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Trypsin_2
XH1_k127_454306_0	671143.DAMO_1073	0.0	1035.0	COG0542@1|root,COG0542@2|Bacteria,2NNNE@2323|unclassified Bacteria	2|Bacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
XH1_k127_454306_4	880073.Calab_1105	7.98e-102	377.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713,ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.33.1	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Peptidase_S8,Pkinase,VCBS
XH1_k127_454306_13	1131269.AQVV01000040_gene1641	1.096e-22	113.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
XH1_k127_454306_2	240302.BN982_01080	2.044e-122	404.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,3NDAF@45667|Halobacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_454306_7	56780.SYN_02636	5.905e-76	263.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MQGX@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
XH1_k127_454306_5	1121430.JMLG01000001_gene2205	1.726e-92	314.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
XH1_k127_454306_1	945713.IALB_1465	3.969e-166	554.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
XH1_k127_454306_17	526222.Desal_2850	2.637e-14	75.0	COG1141@1|root,COG1141@2|Bacteria,1PZW4@1224|Proteobacteria,43EI6@68525|delta/epsilon subdivisions,2X0RI@28221|Deltaproteobacteria,2MD7N@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Divergent 4Fe-4S mono-cluster	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
XH1_k127_4562499_2	240015.ACP_0760	1.2e-70	246.0	COG2972@1|root,COG2972@2|Bacteria,3Y3NH@57723|Acidobacteria,2JHT4@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,His_kinase
XH1_k127_4562499_3	1340493.JNIF01000003_gene3310	1.225e-56	207.0	COG3279@1|root,COG3279@2|Bacteria,3Y3HR@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
XH1_k127_4562499_0	1125863.JAFN01000001_gene1761	0.0	1041.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
XH1_k127_4562499_1	1125863.JAFN01000001_gene1760	2.987e-112	384.0	COG3581@1|root,COG3581@2|Bacteria,1PDHS@1224|Proteobacteria,43DP1@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
XH1_k127_4564825_0	204669.Acid345_4392	1.269e-30	140.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
XH1_k127_4566644_48	1047013.AQSP01000109_gene2440	1.05e-17	89.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
XH1_k127_4566644_40	272563.CD630_16930	1.778e-34	136.0	COG1433@1|root,COG1433@2|Bacteria,1VW1T@1239|Firmicutes,24KHS@186801|Clostridia,25RHP@186804|Peptostreptococcaceae	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Nitro_FeMo-Co
XH1_k127_4566644_21	335543.Sfum_0266	9.345e-74	258.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42PQM@68525|delta/epsilon subdivisions,2WJIF@28221|Deltaproteobacteria,2MRCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	HTH_20,Methyltransf_31
XH1_k127_4566644_1	1047013.AQSP01000079_gene2040	1.365e-258	836.0	COG0642@1|root,COG3290@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3292@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3	ko:K07315,ko:K12132,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021	-	-	-	FeS,Fe_hyd_lg_C,Fer4,GGDEF,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Y_Y_Y
XH1_k127_4566644_0	370438.PTH_2131	4.922e-292	908.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24BRX@186801|Clostridia,260H8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
XH1_k127_4566644_35	552811.Dehly_0628	1.045e-39	151.0	COG1144@1|root,COG1144@2|Bacteria,2GAVK@200795|Chloroflexi,34DFQ@301297|Dehalococcoidia	301297|Dehalococcoidia	C	4Fe-4S dicluster domain	porD	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
XH1_k127_4566644_5	706587.Desti_5625	4.676e-155	498.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MQ4Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase alpha subunit	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
XH1_k127_4566644_9	56780.SYN_00154	5.998e-121	402.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MQUN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase beta subunit	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
XH1_k127_4566644_30	243164.DET0728	3.163e-46	172.0	COG1905@1|root,COG1905@2|Bacteria,2G6Q5@200795|Chloroflexi,34CUJ@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
XH1_k127_4566644_3	439235.Dalk_5089	2.478e-251	788.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MJ8N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00124,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
XH1_k127_4566644_22	552811.Dehly_0623	3.812e-65	232.0	COG3383@1|root,COG3383@2|Bacteria,2GAS8@200795|Chloroflexi,34D7W@301297|Dehalococcoidia	301297|Dehalococcoidia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4
XH1_k127_4566644_25	706587.Desti_5623	1.347e-61	218.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WQFN@28221|Deltaproteobacteria,2MQDU@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,POR
XH1_k127_4566644_11	1379698.RBG1_1C00001G0687	1.484e-112	378.0	COG1109@1|root,COG1109@2|Bacteria,2NNM3@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
XH1_k127_4566644_4	880073.Calab_0773	2.165e-245	773.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
XH1_k127_4566644_37	552398.HMPREF0866_02844	1.11e-38	152.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3WJG0@541000|Ruminococcaceae	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
XH1_k127_4566644_51	880070.Cycma_4398	8.862e-06	57.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,47RVI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4566644_26	1379698.RBG1_1C00001G0425	2.54e-56	203.0	COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria	2|Bacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
XH1_k127_4566644_36	518766.Rmar_2127	6.533e-39	158.0	COG1420@1|root,COG1420@2|Bacteria,4PEC8@976|Bacteroidetes,1FIUB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
XH1_k127_4566644_43	1120973.AQXL01000075_gene966	5.39e-28	122.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,278G9@186823|Alicyclobacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
XH1_k127_4566644_2	1379698.RBG1_1C00001G1489	1.249e-251	790.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
XH1_k127_4566644_7	1379698.RBG1_1C00001G1488	3.041e-133	434.0	COG0484@1|root,COG0484@2|Bacteria,2NNNG@2323|unclassified Bacteria	2|Bacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
XH1_k127_4566644_46	243233.MCA0018	2.692e-22	112.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1XEU6@135618|Methylococcales	135618|Methylococcales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
XH1_k127_4566644_39	648996.Theam_0524	1.606e-35	140.0	COG1610@1|root,COG1610@2|Bacteria,2G4V2@200783|Aquificae	200783|Aquificae	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
XH1_k127_4566644_50	420662.Mpe_A2152	6.283e-08	61.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2VUM6@28216|Betaproteobacteria,1KM7I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
XH1_k127_4566644_10	370438.PTH_1939	2.113e-118	411.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
XH1_k127_4566644_13	1379698.RBG1_1C00001G1481	1.035e-102	377.0	COG0358@1|root,COG0358@2|Bacteria,2NNNJ@2323|unclassified Bacteria	2|Bacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
XH1_k127_4566644_8	215803.DB30_4278	3.484e-129	443.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
XH1_k127_4566644_41	1296415.JACC01000003_gene3109	2.676e-31	131.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia,2YK50@290174|Aquimarina	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
XH1_k127_4566644_31	644968.DFW101_0743	4.922e-46	171.0	COG0454@1|root,COG0456@2|Bacteria,1Q1ZZ@1224|Proteobacteria,42USA@68525|delta/epsilon subdivisions,2WQ2Q@28221|Deltaproteobacteria,2MB9I@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
XH1_k127_4566644_45	243090.RB4278	1.437e-23	113.0	COG1633@1|root,COG4447@1|root,COG1633@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	AurF,Ferritin-like,Sortilin-Vps10
XH1_k127_4566644_47	289376.THEYE_A1031	1.267e-19	100.0	COG1579@1|root,COG1579@2|Bacteria,3J0UV@40117|Nitrospirae	40117|Nitrospirae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
XH1_k127_4566644_42	287986.DV20_25975	5.864e-31	129.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4E04U@85010|Pseudonocardiales	201174|Actinobacteria	GL	phosphoglycerate mutase	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
XH1_k127_4566644_44	927677.ALVU02000001_gene2473	7.214e-28	121.0	COG3339@1|root,COG3339@2|Bacteria,1G7DF@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
XH1_k127_4566644_6	1379698.RBG1_1C00001G1680	1.022e-140	458.0	COG0513@1|root,COG0513@2|Bacteria,2NP0A@2323|unclassified Bacteria	2|Bacteria	JKL	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
XH1_k127_4566644_19	868595.Desca_2670	1.608e-79	283.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,260ZM@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
XH1_k127_4566644_24	1047013.AQSP01000130_gene1863	2.927e-63	235.0	28KQH@1|root,2ZA8A@2|Bacteria	2|Bacteria	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
XH1_k127_4566644_27	526227.Mesil_0296	3.589e-54	196.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1WN7K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087
XH1_k127_4566644_12	309807.SRU_2233	7.125e-105	362.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1FJ1M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
XH1_k127_4566644_34	688269.Theth_1053	1.521e-40	171.0	COG1490@1|root,COG1490@2|Bacteria,2GCYQ@200918|Thermotogae	200918|Thermotogae	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
XH1_k127_4566644_33	1121468.AUBR01000001_gene496	8.236e-42	165.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,42GIM@68295|Thermoanaerobacterales	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
XH1_k127_4566644_14	867903.ThesuDRAFT_00760	1.521e-94	324.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,3WCG0@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
XH1_k127_4566644_28	324602.Caur_2399	6.914e-53	190.0	COG0102@1|root,COG0102@2|Bacteria,2G6M4@200795|Chloroflexi,3776H@32061|Chloroflexia	32061|Chloroflexia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
XH1_k127_4566644_38	1279038.KB907339_gene1232	4.018e-36	143.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2U5B5@28211|Alphaproteobacteria,2JRR2@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
XH1_k127_4566644_16	1382304.JNIL01000001_gene579	4.882e-84	287.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,27885@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
XH1_k127_4566644_20	246194.CHY_1786	1.397e-76	261.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
XH1_k127_4566644_17	1304874.JAFY01000007_gene2515	1.374e-81	279.0	COG0528@1|root,COG0528@2|Bacteria,3TA8R@508458|Synergistetes	508458|Synergistetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
XH1_k127_4566644_29	1329516.JPST01000063_gene1790	3.192e-52	190.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,27AVW@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosome recycling factor	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
XH1_k127_4566644_18	264732.Moth_1038	5.833e-81	277.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,42F7X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
XH1_k127_4566644_32	1499967.BAYZ01000078_gene990	5.007e-46	178.0	COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
XH1_k127_4566644_15	1123508.JH636442_gene4046	6.572e-89	318.0	COG0743@1|root,COG0743@2|Bacteria,2IY3M@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
XH1_k127_4566644_23	1158318.ATXC01000001_gene1406	3.885e-64	238.0	COG0750@1|root,COG0750@2|Bacteria,2G3QY@200783|Aquificae	200783|Aquificae	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
XH1_k127_456705_4	1379698.RBG1_1C00001G1816	1.182e-33	144.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
XH1_k127_456705_2	1123234.AUKI01000015_gene2335	2.079e-67	249.0	COG0438@1|root,COG0438@2|Bacteria,4NQEG@976|Bacteroidetes,1I3CT@117743|Flavobacteriia	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
XH1_k127_456705_1	945713.IALB_0376	7.569e-75	270.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	glmU	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_4
XH1_k127_456705_5	1382359.JIAL01000001_gene2812	1.419e-27	113.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria,2JJMF@204432|Acidobacteriia	204432|Acidobacteriia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
XH1_k127_456705_7	714943.Mucpa_2551	0.0006648	44.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_456705_3	326427.Cagg_2013	4.918e-60	232.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
XH1_k127_456705_0	269799.Gmet_0555	1.589e-85	292.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_4568522_2	1047013.AQSP01000051_gene2576	8.978e-23	113.0	COG2220@1|root,COG2220@2|Bacteria,2NRBH@2323|unclassified Bacteria	2|Bacteria	S	Beta-lactamase superfamily domain	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
XH1_k127_4568522_0	45151.EDU47283	2.416e-42	175.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta	33154|Opisthokonta	M	protein localization to T-tubule	-	-	-	ko:K10380	ko04624,ko05205,map04624,map05205	-	-	-	ko00000,ko00001,ko04812	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Death,HET,NACHT,ZU5
XH1_k127_4568522_1	1442599.JAAN01000030_gene2064	2.06e-37	144.0	COG1695@1|root,COG1695@2|Bacteria,1NJSY@1224|Proteobacteria,1SG6R@1236|Gammaproteobacteria,1X6UG@135614|Xanthomonadales	135614|Xanthomonadales	K	PadR family transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
XH1_k127_4568522_3	666685.R2APBS1_1312	2.82e-21	98.0	COG4709@1|root,COG4709@2|Bacteria,1NX5K@1224|Proteobacteria,1SPS6@1236|Gammaproteobacteria,1X34I@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	Sensor
XH1_k127_4589213_0	1047013.AQSP01000130_gene1851	4.446e-67	246.0	COG1453@1|root,COG1453@2|Bacteria,2NNZZ@2323|unclassified Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
XH1_k127_4589213_1	113395.AXAI01000001_gene2817	0.000595	50.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3JRSC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
XH1_k127_4590286_11	1267535.KB906767_gene1673	2.024e-89	314.0	2DV1K@1|root,33TIU@2|Bacteria,3Y68F@57723|Acidobacteria,2JKW2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4590286_24	1246995.AFR_16455	1.108e-06	61.0	2CKMT@1|root,32YH1@2|Bacteria,2IJID@201174|Actinobacteria	201174|Actinobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
XH1_k127_4590286_2	1047013.AQSP01000140_gene2469	2.579e-257	800.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
XH1_k127_4590286_12	760568.Desku_1388	4.594e-83	286.0	COG1032@1|root,COG1032@2|Bacteria,1TQF0@1239|Firmicutes,24A0T@186801|Clostridia,2611F@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
XH1_k127_4590286_21	1379698.RBG1_1C00001G1516	3.778e-14	87.0	COG2982@1|root,COG2982@2|Bacteria,2NRT5@2323|unclassified Bacteria	2|Bacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289,ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA,AsmA_1,AsmA_2,DUF3971,DctA-YdbH
XH1_k127_4590286_22	562970.Btus_3146	1.86e-11	76.0	COG4625@1|root,COG5492@1|root,COG4625@2|Bacteria,COG5492@2|Bacteria,1V72Z@1239|Firmicutes	1239|Firmicutes	N	PFAM S-layer domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,SLH
XH1_k127_4590286_16	1047013.AQSP01000139_gene2393	7.198e-61	217.0	COG1704@1|root,COG1704@2|Bacteria,2NPIW@2323|unclassified Bacteria	2|Bacteria	S	LemA family	lemA2	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
XH1_k127_4590286_9	42256.RradSPS_0124	8.121e-106	351.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
XH1_k127_4590286_10	1379698.RBG1_1C00001G1340	3.781e-93	321.0	COG2309@1|root,COG2309@2|Bacteria,2NPR4@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
XH1_k127_4590286_19	469383.Cwoe_3518	1.255e-37	164.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
XH1_k127_4590286_23	443144.GM21_1641	1.004e-06	61.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_4590286_5	909663.KI867150_gene2237	1.043e-193	616.0	COG0034@1|root,COG0034@2|Bacteria,1R7JX@1224|Proteobacteria,42MAC@68525|delta/epsilon subdivisions,2WKFD@28221|Deltaproteobacteria,2MQ6P@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Glutamine amidotransferase domain	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
XH1_k127_4590286_17	646529.Desaci_2459	3.189e-54	198.0	COG0242@1|root,COG0242@2|Bacteria,1V41Q@1239|Firmicutes,24I9S@186801|Clostridia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
XH1_k127_4590286_26	768670.Calni_0211	0.0004174	52.0	COG2110@1|root,COG2110@2|Bacteria,2GFMG@200930|Deferribacteres	200930|Deferribacteres	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
XH1_k127_4590286_7	234267.Acid_1536	4.557e-166	547.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
XH1_k127_4590286_0	1499967.BAYZ01000095_gene4126	4.225e-275	892.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
XH1_k127_4590286_25	1325130.HFN_2039	7.889e-06	54.0	2BIKQ@1|root,32CTJ@2|Bacteria,1Q01P@1224|Proteobacteria,42Y1E@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4590286_6	1265505.ATUG01000001_gene3174	6.004e-173	557.0	COG1042@1|root,COG1042@2|Bacteria,1R8Q6@1224|Proteobacteria,42NR2@68525|delta/epsilon subdivisions,2WM2A@28221|Deltaproteobacteria,2MN2C@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2,Succ_CoA_lig
XH1_k127_4590286_14	1125863.JAFN01000001_gene3212	4.021e-63	242.0	COG0045@1|root,COG0045@2|Bacteria,1RHNF@1224|Proteobacteria,42TCD@68525|delta/epsilon subdivisions,2WPBK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5
XH1_k127_4590286_13	665571.STHERM_c20760	5.175e-75	278.0	COG2204@1|root,COG2204@2|Bacteria,2J5NY@203691|Spirochaetes	203691|Spirochaetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_4590286_8	909663.KI867151_gene2967	1.322e-117	403.0	COG4191@1|root,COG4191@2|Bacteria,1PGQG@1224|Proteobacteria,439Y9@68525|delta/epsilon subdivisions,2X1VH@28221|Deltaproteobacteria,2MRRE@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
XH1_k127_4590286_1	909663.KI867151_gene2966	4.6e-269	870.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1NT36@1224|Proteobacteria,42ZEC@68525|delta/epsilon subdivisions,2WU3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
XH1_k127_4590286_3	469381.Dpep_0068	5.068e-252	792.0	COG1894@1|root,COG1894@2|Bacteria,3TAIT@508458|Synergistetes	508458|Synergistetes	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
XH1_k127_4590286_15	909663.KI867151_gene2964	1.079e-61	216.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,43DNM@68525|delta/epsilon subdivisions,2X6M5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
XH1_k127_4590286_18	909663.KI867151_gene2963	5.845e-54	203.0	COG2204@1|root,COG2204@2|Bacteria,1Q5EK@1224|Proteobacteria,433QZ@68525|delta/epsilon subdivisions,2WXYI@28221|Deltaproteobacteria	2|Bacteria	T	cheY-homologous receiver domain	-	-	2.1.1.80,3.1.1.61,3.1.3.3	ko:K03413,ko:K07315,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03021	-	-	-	HATPase_c,HDOD,HD_5,Response_reg
XH1_k127_4590286_4	387092.NIS_0283	3.936e-199	631.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2YMAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
XH1_k127_4590286_20	445975.COLSTE_02307	1.502e-21	99.0	COG1725@1|root,COG1725@2|Bacteria,2IT01@201174|Actinobacteria,4CW4J@84998|Coriobacteriia	84998|Coriobacteriia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
XH1_k127_4603422_5	555079.Toce_1712	1.554e-12	78.0	2DMAW@1|root,32EM1@2|Bacteria,1UPNC@1239|Firmicutes,25HJQ@186801|Clostridia,42JH2@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4603422_4	635013.TherJR_2774	2.125e-77	277.0	COG3437@1|root,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,267DF@186807|Peptococcaceae	186801|Clostridia	KT	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,Hpt,Response_reg
XH1_k127_4603422_2	240015.ACP_1372	1.271e-108	364.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
XH1_k127_4603422_3	574376.BAMA_06490	4.326e-102	342.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1TQX3@1239|Firmicutes,4HCI6@91061|Bacilli,1ZE72@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
XH1_k127_4603422_1	56780.SYN_00402	5.391e-169	544.0	COG0415@1|root,COG0415@2|Bacteria,1RG4D@1224|Proteobacteria,42NWP@68525|delta/epsilon subdivisions,2WJUA@28221|Deltaproteobacteria,2MQYG@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
XH1_k127_4603422_7	880073.Calab_3764	0.0002456	48.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
XH1_k127_4603422_6	688269.Theth_0183	4.159e-11	68.0	COG1366@1|root,COG1366@2|Bacteria,2GDAN@200918|Thermotogae	200918|Thermotogae	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
XH1_k127_4603422_8	1174528.JH992898_gene3813	0.0006179	52.0	COG1749@1|root,COG1749@2|Bacteria,1G2ZW@1117|Cyanobacteria,1JK8Y@1189|Stigonemataceae	1117|Cyanobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,DUF4082
XH1_k127_4603422_0	237368.SCABRO_01504	6.944e-190	607.0	COG0659@1|root,COG0659@2|Bacteria,2IX8K@203682|Planctomycetes	203682|Planctomycetes	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
XH1_k127_4621175_0	1379698.RBG1_1C00001G1656	0.0	1069.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
XH1_k127_4621175_3	926567.TheveDRAFT_1028	2.676e-31	141.0	COG1520@1|root,COG1520@2|Bacteria,3TB0M@508458|Synergistetes	508458|Synergistetes	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
XH1_k127_4621175_7	1173263.Syn7502_00997	1.041e-13	79.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,1G30V@1117|Cyanobacteria,1H32A@1129|Synechococcus	1117|Cyanobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_1,TPR_11,TPR_2,TPR_8
XH1_k127_4621175_6	439235.Dalk_2214	1.201e-16	91.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1PDTX@1224|Proteobacteria,42RK5@68525|delta/epsilon subdivisions,2WNZC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
XH1_k127_4621175_5	521011.Mpal_0840	3.509e-20	105.0	COG3540@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03613@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
XH1_k127_4621175_4	404589.Anae109_1953	2.75e-24	120.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,2YV6T@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_19,TPR_6,TPR_8
XH1_k127_4621175_1	1123376.AUIU01000007_gene1180	6.353e-183	610.0	COG0519@1|root,COG0519@2|Bacteria,3J0A2@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
XH1_k127_4621175_2	240015.ACP_3297	1.739e-149	489.0	COG0138@1|root,COG0138@2|Bacteria,3Y2QI@57723|Acidobacteria,2JHSU@204432|Acidobacteriia	204432|Acidobacteriia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
XH1_k127_4640413_3	546274.EIKCOROL_00442	5.072e-08	57.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2VHNS@28216|Betaproteobacteria,2KQ0K@206351|Neisseriales	206351|Neisseriales	M	Bifunctional protein RfaE, domain I	rfaE	-	2.7.1.167	ko:K21344	ko00540,map00540	M00064	R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
XH1_k127_4640413_2	665942.HMPREF1022_01288	8.1e-10	71.0	COG0438@1|root,COG1136@1|root,COG0438@2|Bacteria,COG1136@2|Bacteria,1NQWI@1224|Proteobacteria,42YXX@68525|delta/epsilon subdivisions,2WTMM@28221|Deltaproteobacteria,2M7Z8@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,Glycos_transf_1
XH1_k127_4640413_0	1278073.MYSTI_05166	1.896e-40	158.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
XH1_k127_4640413_1	671143.DAMO_0272	3.424e-31	133.0	COG0859@1|root,COG3307@1|root,COG0859@2|Bacteria,COG3307@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	rfaQ	-	-	ko:K02841,ko:K02843,ko:K02847,ko:K02849,ko:K21003	ko00540,ko01100,ko02025,map00540,map01100,map02025	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000	9.B.67.4,9.B.67.5	GT9	-	Glyco_transf_25,Glyco_transf_9,Wzy_C
XH1_k127_4674814_0	247490.KSU1_C0515	5.611e-137	445.0	COG1063@1|root,COG1063@2|Bacteria,2J2DX@203682|Planctomycetes	203682|Planctomycetes	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
XH1_k127_4674814_1	1047013.AQSP01000037_gene1326	2.901e-110	388.0	COG1830@1|root,COG1830@2|Bacteria,2NPYC@2323|unclassified Bacteria	2|Bacteria	G	DeoC/LacD family aldolase	lsrF	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747	2.3.1.245,4.1.2.13	ko:K08321,ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02024,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map02024	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
XH1_k127_4674814_3	331869.BAL199_25634	3.252e-09	70.0	COG0477@1|root,COG2814@2|Bacteria,1QW9T@1224|Proteobacteria,2TY4I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
XH1_k127_4674814_2	1047013.AQSP01000099_gene1506	4.479e-73	275.0	COG1355@1|root,COG1355@2|Bacteria,2NQS3@2323|unclassified Bacteria	2|Bacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
XH1_k127_4675666_1	459349.CLOAM0005	5.274e-26	114.0	COG1267@1|root,COG1267@2|Bacteria,2NPTB@2323|unclassified Bacteria	2|Bacteria	I	Phosphatidylglycerophosphatase A	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0195,iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
XH1_k127_4675666_0	298654.FraEuI1c_1130	2.57e-51	201.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4ERZM@85013|Frankiales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
XH1_k127_4740883_6	1121405.dsmv_3144	1.057e-67	243.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,2MIFD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
XH1_k127_4740883_10	1379698.RBG1_1C00001G1645	2.12e-41	161.0	COG2121@1|root,COG2121@2|Bacteria,2NPP6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF374)	MA20_05800	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K09778	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	DUF374
XH1_k127_4740883_9	56780.SYN_01563	9.986e-42	168.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria,2MQI9@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
XH1_k127_4740883_0	589865.DaAHT2_2040	1.876e-171	554.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MIMB@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
XH1_k127_4740883_11	1379270.AUXF01000005_gene601	4.923e-19	100.0	2E5IJ@1|root,3309Y@2|Bacteria,1ZTU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4740883_7	589865.DaAHT2_0018	4.84e-55	218.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
XH1_k127_4740883_2	335543.Sfum_1996	7.88e-109	383.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
XH1_k127_4740883_1	880073.Calab_0869	2.145e-119	410.0	COG1180@1|root,COG1180@2|Bacteria,2NNMV@2323|unclassified Bacteria	2|Bacteria	O	Elongator protein 3, MiaB family, Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
XH1_k127_4740883_13	321327.CYA_2879	2.6e-10	74.0	2DN50@1|root,32VJ4@2|Bacteria,1GND9@1117|Cyanobacteria,1H0SG@1129|Synechococcus	1117|Cyanobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
XH1_k127_4740883_4	1499967.BAYZ01000095_gene4168	8.384e-98	359.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
XH1_k127_4740883_8	935948.KE386495_gene1732	8.91e-50	186.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,42FRK@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5
XH1_k127_4740883_3	335543.Sfum_1755	7.375e-98	332.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2MR9V@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_4740883_5	290397.Adeh_0430	2.491e-72	258.0	COG1801@1|root,COG1801@2|Bacteria,1N4QE@1224|Proteobacteria,42PDW@68525|delta/epsilon subdivisions,2WK6H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
XH1_k127_4740883_12	1210908.HSB1_32670	3.364e-12	77.0	arCOG00567@1|root,arCOG00567@2157|Archaea,2XVU1@28890|Euryarchaeota,23UZV@183963|Halobacteria	183963|Halobacteria	M	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_4748920_3	290397.Adeh_0751	2.762e-53	195.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,2Z0FU@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
XH1_k127_4748920_1	485913.Krac_11147	5.384e-56	207.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
XH1_k127_4748920_5	1096930.L284_21840	3.912e-24	109.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria	1224|Proteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
XH1_k127_4748920_4	1094980.Mpsy_1210	1.159e-27	118.0	COG2426@1|root,arCOG01330@2157|Archaea,2XZ2Y@28890|Euryarchaeota,2NAQX@224756|Methanomicrobia	224756|Methanomicrobia	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
XH1_k127_4748920_2	321327.CYA_0908	5.985e-54	200.0	COG2518@1|root,COG2518@2|Bacteria,1G5KC@1117|Cyanobacteria,1H0H3@1129|Synechococcus	1117|Cyanobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
XH1_k127_4748920_0	671143.DAMO_1380	3.971e-68	240.0	COG0496@1|root,COG0496@2|Bacteria,2NPCG@2323|unclassified Bacteria	2|Bacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	iSFxv_1172.SFxv_3035	SurE
XH1_k127_4748920_6	497964.CfE428DRAFT_4728	7.857e-20	92.0	COG0463@1|root,COG0463@2|Bacteria,46UW3@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH1_k127_4751725_3	637390.AFOH01000025_gene1036	2.622e-23	102.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
XH1_k127_4751725_2	321332.CYB_1547	6.457e-32	133.0	COG0659@1|root,COG0659@2|Bacteria,1GPES@1117|Cyanobacteria,1H323@1129|Synechococcus	1117|Cyanobacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4751725_4	44251.PDUR_04365	1.377e-12	81.0	COG3656@1|root,COG3656@2|Bacteria,1VF97@1239|Firmicutes,4HY7C@91061|Bacilli,271ZZ@186822|Paenibacillaceae	91061|Bacilli	S	Predicted periplasmic protein (DUF2271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2271
XH1_k127_4751725_0	748449.Halha_2091	1.412e-97	341.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WABA@53433|Halanaerobiales	186801|Clostridia	P	TIGRFAM potassium uptake protein, TrkH family	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
XH1_k127_4751725_1	643867.Ftrac_2536	2.459e-42	164.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,47PBV@768503|Cytophagia	976|Bacteroidetes	P	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
XH1_k127_47660_0	858215.Thexy_1501	6.026e-93	332.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,42EY4@68295|Thermoanaerobacterales	186801|Clostridia	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
XH1_k127_4766204_5	644966.Tmar_0869	1.527e-57	211.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3WCJ3@538999|Clostridiales incertae sedis	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
XH1_k127_4766204_4	1122927.KB895413_gene1378	2.676e-61	234.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,26SSY@186822|Paenibacillaceae	91061|Bacilli	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
XH1_k127_4766204_1	671143.DAMO_2299	1.483e-107	381.0	COG0771@1|root,COG0771@2|Bacteria,2NP27@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097	Mur_ligase_C,Mur_ligase_M
XH1_k127_4766204_0	1379698.RBG1_1C00001G0393	4.99e-147	476.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
XH1_k127_4766204_3	1121472.AQWN01000005_gene2388	1.117e-78	281.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,260TC@186807|Peptococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
XH1_k127_4766204_2	370438.PTH_1866	1.723e-99	339.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,260X6@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
XH1_k127_4779210_2	243231.GSU3296	5.832e-55	204.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,43TWW@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	larD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3245	FAD-oxidase_C,FAD_binding_4
XH1_k127_4779210_0	1031288.AXAA01000001_gene2328	1.234e-106	360.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,36DUZ@31979|Clostridiaceae	186801|Clostridia	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
XH1_k127_4779210_3	1158146.KB907121_gene1146	1.069e-51	190.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1WY42@135613|Chromatiales	135613|Chromatiales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
XH1_k127_4779210_4	333138.LQ50_06805	4.925e-25	114.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,1ZFNI@1386|Bacillus	91061|Bacilli	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
XH1_k127_4779210_1	1379698.RBG1_1C00001G1254	3.892e-70	255.0	COG4796@1|root,COG4796@2|Bacteria,2NPEQ@2323|unclassified Bacteria	2|Bacteria	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
XH1_k127_4795254_1	448385.sce6916	0.0005745	53.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,42PJA@68525|delta/epsilon subdivisions,2WMG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
XH1_k127_4795254_0	459349.CLOAM1586	1.807e-46	193.0	COG1196@1|root,COG1196@2|Bacteria,2NNSS@2323|unclassified Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4801165_0	459349.CLOAM0985	6.669e-20	104.0	COG1361@1|root,COG1361@2|Bacteria,2NQI0@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
XH1_k127_4867695_4	56780.SYN_00357	1.536e-35	143.0	COG1351@1|root,COG1351@2|Bacteria,1QF4I@1224|Proteobacteria,43A0P@68525|delta/epsilon subdivisions,2X9Q1@28221|Deltaproteobacteria,2MSCD@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Thymidylate synthase complementing protein	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
XH1_k127_4867695_3	1047013.AQSP01000128_gene411	3.847e-42	160.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
XH1_k127_4867695_2	742740.HMPREF9474_01719	1.494e-47	190.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,21XS8@1506553|Lachnoclostridium	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
XH1_k127_4867695_1	177437.HRM2_25370	2.691e-106	357.0	COG0535@1|root,COG0535@2|Bacteria,1RAHK@1224|Proteobacteria,42PBP@68525|delta/epsilon subdivisions,2WKMH@28221|Deltaproteobacteria,2MMKJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
XH1_k127_4867695_0	926550.CLDAP_29660	1.005e-133	436.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
XH1_k127_4867695_5	1379698.RBG1_1C00001G1816	5.138e-21	101.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
XH1_k127_4870130_6	1121918.ARWE01000001_gene3499	2.539e-18	95.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,43U4D@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	AIR synthase related protein, C-terminal domain	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
XH1_k127_4870130_1	760568.Desku_2838	2.613e-104	364.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
XH1_k127_4870130_3	386456.JQKN01000002_gene2419	6.646e-29	125.0	COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,23NYH@183925|Methanobacteria	183925|Methanobacteria	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
XH1_k127_4870130_7	796620.VIBC2010_09227	1.123e-11	76.0	COG1266@1|root,COG1266@2|Bacteria,1P0IE@1224|Proteobacteria,1RS9M@1236|Gammaproteobacteria,1XV8N@135623|Vibrionales	135623|Vibrionales	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
XH1_k127_4870130_4	861299.J421_3007	6.199e-22	99.0	2EQ8R@1|root,33HV0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4870130_5	255470.cbdbA378	2.341e-19	95.0	COG1656@1|root,COG1656@2|Bacteria,2G6GZ@200795|Chloroflexi,34DKC@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
XH1_k127_4870130_0	945713.IALB_2034	6.351e-180	586.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
XH1_k127_4870130_2	665571.STHERM_c14250	3.507e-33	132.0	COG1194@1|root,COG1194@2|Bacteria,2J5B8@203691|Spirochaetes	203691|Spirochaetes	L	A G-specific	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
XH1_k127_4924729_0	204669.Acid345_2969	1.264e-228	735.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
XH1_k127_4924729_14	413404.Rmag_0400	3.245e-05	53.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1J5SA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
XH1_k127_4924729_13	1408312.JNJS01000001_gene1728	2.289e-09	71.0	2CHFB@1|root,30T97@2|Bacteria,1V5ED@1239|Firmicutes,24I9Q@186801|Clostridia,3NHUQ@46205|Pseudobutyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4924729_3	1041930.Mtc_0044	8.051e-79	280.0	COG0535@1|root,arCOG00941@2157|Archaea,2Y8D6@28890|Euryarchaeota,2NBHW@224756|Methanomicrobia	224756|Methanomicrobia	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
XH1_k127_4924729_7	698757.Pogu_0667	6.756e-56	209.0	COG0778@1|root,arCOG00288@2157|Archaea,2XQMS@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
XH1_k127_4924729_6	1122134.KB893650_gene386	6.844e-60	215.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,1S82H@1236|Gammaproteobacteria,1XJE4@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
XH1_k127_4924729_10	1232410.KI421414_gene2927	3.863e-31	133.0	COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,42V8E@68525|delta/epsilon subdivisions,2WS8I@28221|Deltaproteobacteria,43SQU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
XH1_k127_4924729_8	247490.KSU1_D0807	4.354e-50	189.0	2BRMQ@1|root,32KM4@2|Bacteria,2J4AR@203682|Planctomycetes	247490.KSU1_D0807|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4924729_4	1167006.UWK_01691	1.632e-76	267.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,42NZ8@68525|delta/epsilon subdivisions,2WK0Y@28221|Deltaproteobacteria,2MPFD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258,ko:K07262	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
XH1_k127_4924729_2	1379698.RBG1_1C00001G1345	5.121e-88	307.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,SSF,SpoIIE
XH1_k127_4924729_1	338963.Pcar_2073	9.773e-129	429.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,43SPT@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
XH1_k127_4924729_11	945713.IALB_2396	8.331e-26	125.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Sortilin-Vps10
XH1_k127_4924729_9	395493.BegalDRAFT_2794	4.286e-34	143.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,1SDH5@1236|Gammaproteobacteria,462GG@72273|Thiotrichales	72273|Thiotrichales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
XH1_k127_4924729_12	84531.JMTZ01000010_gene3141	1.102e-21	96.0	2DCFR@1|root,2ZDYQ@2|Bacteria,1RB5X@1224|Proteobacteria,1RN4F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4938745_1	880073.Calab_0680	6.391e-39	151.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
XH1_k127_4938745_2	880073.Calab_2295	6.715e-26	111.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	spoIIAA	-	-	ko:K02066,ko:K04749	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000,ko03021	3.A.1.27	-	-	APH,STAS,STAS_2
XH1_k127_4938745_5	1123393.KB891333_gene2602	1.643e-06	60.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria	28216|Betaproteobacteria	O	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,SEC-C,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
XH1_k127_4938745_0	502025.Hoch_4669	4.097e-46	176.0	COG1192@1|root,COG1192@2|Bacteria,1QW1T@1224|Proteobacteria,43BRW@68525|delta/epsilon subdivisions,2X72Q@28221|Deltaproteobacteria,2YZTD@29|Myxococcales	28221|Deltaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
XH1_k127_4938745_3	1379698.RBG1_1C00001G1332	3.995e-18	98.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
XH1_k127_4938745_4	880073.Calab_2295	9.302e-18	97.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	spoIIAA	-	-	ko:K02066,ko:K04749	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000,ko03021	3.A.1.27	-	-	APH,STAS,STAS_2
XH1_k127_4966701_3	1047013.AQSP01000140_gene2549	2.456e-115	388.0	COG1067@1|root,COG1067@2|Bacteria,2NP29@2323|unclassified Bacteria	2|Bacteria	O	peptidase S16	ycbZ	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
XH1_k127_4966701_15	290318.Cvib_1136	4.125e-28	131.0	COG0394@1|root,COG0394@2|Bacteria,1FF6H@1090|Chlorobi	1090|Chlorobi	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
XH1_k127_4966701_13	1191523.MROS_0927	4.627e-48	193.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	-
XH1_k127_4966701_8	56780.SYN_02059	6.599e-82	284.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2MQHV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
XH1_k127_4966701_1	589865.DaAHT2_0700	1.273e-157	512.0	COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MPI2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
XH1_k127_4966701_7	1156937.MFUM_960011	4.283e-86	304.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,37GFQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
XH1_k127_4966701_12	243233.MCA2831	4.371e-63	226.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1S2WI@1236|Gammaproteobacteria,1XEYK@135618|Methylococcales	135618|Methylococcales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
XH1_k127_4966701_11	926550.CLDAP_14500	1.056e-66	245.0	COG0013@1|root,COG0013@2|Bacteria,2G6Z3@200795|Chloroflexi	200795|Chloroflexi	J	Threonyl alanyl tRNA synthetase SAD	-	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
XH1_k127_4966701_10	671143.DAMO_0676	1.548e-69	262.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
XH1_k127_4966701_2	517418.Ctha_0502	8.279e-140	456.0	COG0577@1|root,COG0577@2|Bacteria,1FDCY@1090|Chlorobi	1090|Chlorobi	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
XH1_k127_4966701_4	517418.Ctha_0503	2.61e-100	334.0	COG1136@1|root,COG1136@2|Bacteria,1FDKJ@1090|Chlorobi	2|Bacteria	P	PFAM ABC transporter related	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_4966701_5	1499967.BAYZ01000034_gene1067	1.976e-97	336.0	COG0845@1|root,COG0845@2|Bacteria,2NPBH@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	macA_1	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
XH1_k127_4966701_9	1254432.SCE1572_01775	4.829e-76	274.0	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
XH1_k127_4966701_0	880073.Calab_3693	4.987e-190	614.0	COG1297@1|root,COG1297@2|Bacteria,2NPP0@2323|unclassified Bacteria	2|Bacteria	S	OPT oligopeptide transporter protein	oliA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	OPT
XH1_k127_4966701_16	272559.BF9343_0961	1.579e-12	78.0	2DRT8@1|root,33CYG@2|Bacteria,4PHKQ@976|Bacteroidetes,2FTAE@200643|Bacteroidia,4AREX@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	pqqD	-	-	-	-	-	-	-	-	-	-	-	PqqD
XH1_k127_4966701_14	861299.J421_2657	4.424e-41	172.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	2|Bacteria	N	domain, Protein	-	-	3.2.1.4,3.4.17.14	ko:K01179,ko:K07260,ko:K13735	ko00500,ko00550,ko01100,ko01502,ko02020,ko05100,map00500,map00550,map01100,map01502,map02020,map05100	M00651	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	GH5,GH9	-	Big_1,Big_2,Glug,IAT_beta,Invasin_D3,LysM,Mfa_like_1,SLH
XH1_k127_4966701_6	1125863.JAFN01000001_gene1060	1.069e-93	326.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_4976815_4	933262.AXAM01000061_gene1668	8.682e-06	53.0	COG4970@1|root,COG4970@2|Bacteria,1Q0DU@1224|Proteobacteria,42W7A@68525|delta/epsilon subdivisions,2WS6U@28221|Deltaproteobacteria,2MKVN@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
XH1_k127_4976815_5	520709.F985_00355	0.0003183	51.0	COG4967@1|root,COG4967@2|Bacteria,1NI49@1224|Proteobacteria,1SGCQ@1236|Gammaproteobacteria,3NNSU@468|Moraxellaceae	1236|Gammaproteobacteria	NU	type IV pilus modification protein PilV	pilV	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
XH1_k127_4976815_2	383372.Rcas_2197	1.601e-28	134.0	COG4932@1|root,COG4932@2|Bacteria,2GABV@200795|Chloroflexi,3752H@32061|Chloroflexia	32061|Chloroflexia	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
XH1_k127_4976815_0	518766.Rmar_2049	1.665e-292	936.0	COG1506@1|root,COG2706@1|root,COG1506@2|Bacteria,COG2706@2|Bacteria,4PIC9@976|Bacteroidetes,1FKAR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_4976815_1	261292.Nit79A3_2578	2.798e-46	175.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,2W9WV@28216|Betaproteobacteria,373PI@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5042000_0	1265505.ATUG01000003_gene828	3.335e-142	474.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MHYC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
XH1_k127_5042000_1	868595.Desca_1318	8.882e-30	124.0	COG1142@1|root,COG1142@2|Bacteria,1VJF0@1239|Firmicutes,24TWH@186801|Clostridia,266YW@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
XH1_k127_5043407_0	1379698.RBG1_1C00001G0608	4.818e-97	325.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
XH1_k127_5043407_2	459349.CLOAM1790	3.387e-16	92.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
XH1_k127_5043407_1	4098.XP_009606934.1	3.061e-32	143.0	COG4870@1|root,KOG1543@2759|Eukaryota,38765@33090|Viridiplantae,3GN3N@35493|Streptophyta,44MWF@71274|asterids	35493|Streptophyta	O	Belongs to the peptidase C1 family	-	-	-	ko:K13441	ko04626,map04626	-	-	-	ko00000,ko00001,ko01002	-	-	-	Inhibitor_I29,Peptidase_C1
XH1_k127_5069227_4	765913.ThidrDRAFT_3709	1.754e-10	65.0	COG0438@1|root,COG0438@2|Bacteria,1PVZ8@1224|Proteobacteria,1RN11@1236|Gammaproteobacteria,1WXWW@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4
XH1_k127_5069227_1	306281.AJLK01000115_gene5201	1.023e-97	334.0	COG2244@1|root,COG2244@2|Bacteria,1G3H8@1117|Cyanobacteria	1117|Cyanobacteria	S	Membrane protein involved in the export of o-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
XH1_k127_5069227_3	29581.BW37_00587	2.956e-24	106.0	2BHBU@1|root,32BDF@2|Bacteria,1PX25@1224|Proteobacteria,2WCJV@28216|Betaproteobacteria,477T9@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
XH1_k127_5069227_0	187272.Mlg_0131	2.687e-132	441.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1S52E@1236|Gammaproteobacteria,1X2A4@135613|Chromatiales	135613|Chromatiales	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
XH1_k127_5069227_5	1463854.JOHT01000027_gene2486	6.859e-06	59.0	COG0236@1|root,COG0236@2|Bacteria,2GTT5@201174|Actinobacteria	201174|Actinobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
XH1_k127_5069227_2	443143.GM18_0919	2.002e-27	117.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
XH1_k127_5100939_0	1191523.MROS_2798	0.0	1150.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
XH1_k127_5100939_2	1499967.BAYZ01000119_gene3216	1.283e-206	657.0	COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
XH1_k127_5100939_1	1191523.MROS_2800	1.546e-232	727.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gluD	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
XH1_k127_5100939_13	1121373.KB903664_gene2730	0.0004135	46.0	COG2885@1|root,COG2885@2|Bacteria,4NRQ3@976|Bacteroidetes,47S5T@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
XH1_k127_5100939_12	335543.Sfum_3060	5.367e-08	63.0	2CC24@1|root,32VJT@2|Bacteria,1N5Y6@1224|Proteobacteria,42UPP@68525|delta/epsilon subdivisions,2WQ6U@28221|Deltaproteobacteria,2MSB1@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
XH1_k127_5100939_8	1396418.BATQ01000113_gene4691	6.567e-38	154.0	COG0526@1|root,COG0526@2|Bacteria,46TGF@74201|Verrucomicrobia,2IW4P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
XH1_k127_5100939_6	521045.Kole_0574	9.52e-54	203.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
XH1_k127_5100939_4	521045.Kole_0573	7.14e-74	257.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	asrB	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K02823,ko:K16951	ko00240,ko00920,ko01100,ko01120,map00240,map00920,map01100,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS12555	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
XH1_k127_5100939_10	1386969.AWTB01000033_gene4076	6.248e-11	76.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,4GBIH@85026|Gordoniaceae	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
XH1_k127_5100939_9	368408.Tpen_0189	3.048e-29	129.0	COG0437@1|root,arCOG01500@2157|Archaea,2XQF6@28889|Crenarchaeota	28889|Crenarchaeota	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K00124,ko:K21308	ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200	-	R00519,R11487	RC00168,RC02796	ko00000,ko00001	-	-	-	Fer4,Fer4_11,Fer4_3,Fer4_4
XH1_k127_5100939_5	521045.Kole_0571	3.248e-59	223.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
XH1_k127_5100939_7	673860.AciM339_1163	1.037e-51	186.0	COG3260@1|root,arCOG01553@2157|Archaea,2Y8IV@28890|Euryarchaeota,3F3AA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Belongs to the complex I 20 kDa subunit family	-	-	1.12.7.2	ko:K18023	-	-	R00019	-	ko00000,ko01000	-	-	-	Oxidored_q6
XH1_k127_5100939_11	867903.ThesuDRAFT_02258	1.538e-10	72.0	COG0852@1|root,COG0852@2|Bacteria,1UFNI@1239|Firmicutes,24QZN@186801|Clostridia	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
XH1_k127_5100939_3	521045.Kole_0568	7.646e-131	429.0	COG3261@1|root,COG3261@2|Bacteria	2|Bacteria	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_49kDa,NiFeSe_Hases
XH1_k127_5203462_9	404589.Anae109_2277	6.333e-53	194.0	COG1260@1|root,COG1260@2|Bacteria,1N0D9@1224|Proteobacteria,42NWK@68525|delta/epsilon subdivisions,2WM2T@28221|Deltaproteobacteria,2YYFZ@29|Myxococcales	28221|Deltaproteobacteria	I	synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
XH1_k127_5203462_13	861299.J421_0956	4.195e-44	172.0	COG0583@1|root,COG0583@2|Bacteria,1ZU5H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
XH1_k127_5203462_3	1047013.AQSP01000098_gene2568	1.528e-132	450.0	COG1042@1|root,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria	2|Bacteria	C	synthetase (ADP forming), alpha	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
XH1_k127_5203462_16	1201288.M900_2502	1.619e-30	139.0	COG3016@1|root,COG3016@2|Bacteria,1N1D9@1224|Proteobacteria,42TQT@68525|delta/epsilon subdivisions,2MT10@213481|Bdellovibrionales,2WQ8G@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
XH1_k127_5203462_4	1232410.KI421420_gene3142	1.406e-115	394.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,42MBI@68525|delta/epsilon subdivisions,2WIZ9@28221|Deltaproteobacteria,43S5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
XH1_k127_5203462_5	1121405.dsmv_1140	2.754e-75	259.0	COG0569@1|root,COG0569@2|Bacteria,1R7KM@1224|Proteobacteria,42PJH@68525|delta/epsilon subdivisions,2WMZT@28221|Deltaproteobacteria,2MJ9H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
XH1_k127_5203462_8	880073.Calab_3115	1.826e-72	263.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	dtpD	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1,PTR2
XH1_k127_5203462_2	251221.35214024	3.777e-140	465.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	-	-	-	-	-	-	-	-	-	SSF
XH1_k127_5203462_12	861299.J421_5839	1.743e-46	189.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
XH1_k127_5203462_25	880073.Calab_2248	1.351e-06	61.0	COG0737@1|root,COG4632@1|root,COG0737@2|Bacteria,COG4632@2|Bacteria,2NPYW@2323|unclassified Bacteria	2|Bacteria	G	Phosphodiester glycosidase	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Big_2,Metallophos,NAGPA,Pur_ac_phosph_N,SBP_bac_8,SLH
XH1_k127_5203462_26	1105029.HMPREF1137_1702	1.757e-05	57.0	COG2919@1|root,COG2919@2|Bacteria,2HJCU@201174|Actinobacteria,4D34T@85005|Actinomycetales	201174|Actinobacteria	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
XH1_k127_5203462_0	1329516.JPST01000008_gene2032	1.852e-191	606.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,27B4J@186824|Thermoactinomycetaceae	91061|Bacilli	G	Enolase, N-terminal domain	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
XH1_k127_5203462_14	518766.Rmar_2150	2.143e-39	153.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_5203462_23	765420.OSCT_0654	2.729e-07	62.0	COG3595@1|root,COG3595@2|Bacteria,2G9KA@200795|Chloroflexi,377P5@32061|Chloroflexia	32061|Chloroflexia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
XH1_k127_5203462_24	309800.C498_12563	5.002e-07	62.0	arCOG04555@1|root,arCOG04555@2157|Archaea,2XUY2@28890|Euryarchaeota,23TMB@183963|Halobacteria	183963|Halobacteria	S	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
XH1_k127_5203462_21	84531.JMTZ01000008_gene3338	6.608e-10	72.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1X527@135614|Xanthomonadales	135614|Xanthomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
XH1_k127_5203462_18	459349.CLOAM1563	2.085e-12	78.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.17.22	ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CBM_6,Cellulase,DUF4859,F5_F8_type_C,FlgD_ig
XH1_k127_5203462_7	1125863.JAFN01000001_gene1383	4.959e-73	271.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
XH1_k127_5203462_20	638303.Thal_0503	1.744e-11	78.0	COG0248@1|root,COG0248@2|Bacteria,2G4RG@200783|Aquificae	200783|Aquificae	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
XH1_k127_5203462_1	443144.GM21_0962	1.971e-153	497.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_5203462_6	1316936.K678_05423	9.649e-74	280.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2JQBN@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_5203462_11	1379698.RBG1_1C00001G1236	3.354e-50	192.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
XH1_k127_5203462_10	459349.CLOAM0575	1.111e-50	207.0	COG4412@1|root,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,FlgD_ig,Peptidase_M6
XH1_k127_5203462_17	880073.Calab_0649	3.797e-28	125.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
XH1_k127_5203462_15	1379698.RBG1_1C00001G0342	7.93e-37	149.0	COG2908@1|root,COG2908@2|Bacteria,2NPKW@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
XH1_k127_5268612_9	518766.Rmar_1517	2.819e-13	85.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1FJ24@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
XH1_k127_5268612_0	1121430.JMLG01000009_gene424	0.0	1160.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
XH1_k127_5268612_4	246194.CHY_0489	4.602e-102	344.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,42EZ9@68295|Thermoanaerobacterales	186801|Clostridia	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
XH1_k127_5268612_7	880073.Calab_3240	7.459e-39	153.0	COG0509@1|root,COG0509@2|Bacteria,2NPMR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
XH1_k127_5268612_2	324925.Ppha_0698	4.085e-125	414.0	COG0403@1|root,COG0403@2|Bacteria,1FDMI@1090|Chlorobi	1090|Chlorobi	F	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
XH1_k127_5268612_1	1268072.PSAB_22045	8.498e-175	562.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,26RUP@186822|Paenibacillaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
XH1_k127_5268612_8	292459.STH1918	8.734e-33	139.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,247S9@186801|Clostridia	186801|Clostridia	H	Lipoate-protein ligase	lipM	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
XH1_k127_5268612_5	1519464.HY22_02230	1.12e-93	325.0	COG0601@1|root,COG0601@2|Bacteria,1FDDB@1090|Chlorobi	1090|Chlorobi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
XH1_k127_5268612_6	118005.AWNK01000007_gene700	1.59e-63	232.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	appC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
XH1_k127_5268612_3	867903.ThesuDRAFT_02282	9.774e-107	368.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
XH1_k127_5321818_3	667014.Thein_1233	1.328e-31	130.0	COG0718@1|root,COG0718@2|Bacteria,2GHY9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
XH1_k127_5321818_1	665952.HMPREF1015_03255	4.522e-64	225.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,1ZBDK@1386|Bacillus	91061|Bacilli	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
XH1_k127_5321818_2	1379270.AUXF01000005_gene389	7.985e-37	146.0	COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
XH1_k127_5321818_0	483219.LILAB_17450	6.795e-85	284.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
XH1_k127_5342468_3	1125863.JAFN01000001_gene1610	1.645e-124	415.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
XH1_k127_5342468_1	398767.Glov_2702	3.332e-165	533.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
XH1_k127_5342468_6	1094715.CM001373_gene3315	1.703e-59	215.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,1SVID@1236|Gammaproteobacteria,1JD85@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
XH1_k127_5342468_0	1094715.CM001373_gene3313	1.693e-181	595.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1JDPB@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
XH1_k127_5342468_2	370438.PTH_2547	7.088e-149	485.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,260RX@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
XH1_k127_5342468_5	580340.Tlie_0716	1.751e-69	251.0	COG0265@1|root,COG0265@2|Bacteria,3TACF@508458|Synergistetes	508458|Synergistetes	M	TIGRFAM periplasmic serine protease, Do DeqQ family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
XH1_k127_5342468_4	880073.Calab_2718	2.34e-88	297.0	COG0176@1|root,COG0176@2|Bacteria,2NP61@2323|unclassified Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0295	TAL_FSA
XH1_k127_5342468_7	96561.Dole_0466	2.131e-56	205.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2MJMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
XH1_k127_5362318_1	589865.DaAHT2_2148	1.379e-73	263.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PS7@68525|delta/epsilon subdivisions,2WMMC@28221|Deltaproteobacteria,2MKY8@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
XH1_k127_5362318_0	690850.Desaf_3621	0.0	1120.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
XH1_k127_5385359_15	1128111.HMPREF0870_01903	0.0001924	49.0	COG0848@1|root,COG0848@2|Bacteria,1V4E9@1239|Firmicutes,4H4HU@909932|Negativicutes	909932|Negativicutes	U	Transport energizing protein, ExbD TolR family	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
XH1_k127_5385359_10	880073.Calab_2425	3.705e-19	96.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
XH1_k127_5385359_5	1191523.MROS_2571	2.305e-50	191.0	COG0811@1|root,COG0811@2|Bacteria	2|Bacteria	U	bacteriocin transport	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
XH1_k127_5385359_13	517418.Ctha_2301	7.577e-08	65.0	COG4219@1|root,COG4219@2|Bacteria,1FEKW@1090|Chlorobi	1090|Chlorobi	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5385359_7	880073.Calab_2217	2.848e-47	186.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
XH1_k127_5385359_8	880073.Calab_2402	3.852e-43	181.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5385359_3	1379698.RBG1_1C00001G1820	9.855e-96	349.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
XH1_k127_5385359_9	1161902.HMPREF0378_0329	2.576e-40	160.0	COG1394@1|root,COG1394@2|Bacteria,1TQ1Y@1239|Firmicutes,247TC@186801|Clostridia,3WDBN@538999|Clostridiales incertae sedis	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
XH1_k127_5385359_1	340099.Teth39_2258	4.912e-213	670.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,42FIF@68295|Thermoanaerobacterales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
XH1_k127_5385359_0	2754.EH55_05540	1.523e-234	739.0	COG1155@1|root,COG1155@2|Bacteria,3TA3Y@508458|Synergistetes	508458|Synergistetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
XH1_k127_5385359_12	1158604.I591_00115	3.56e-10	65.0	COG1436@1|root,COG1436@2|Bacteria,1VAX7@1239|Firmicutes,4HMU4@91061|Bacilli,4B2YK@81852|Enterococcaceae	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	ntpG	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
XH1_k127_5385359_11	555079.Toce_2044	7.377e-19	99.0	COG1527@1|root,COG1527@2|Bacteria,1U6WZ@1239|Firmicutes,249XD@186801|Clostridia,42EZR@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM H -transporting two-sector ATPase, C (AC39) subunit	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
XH1_k127_5385359_14	592027.CLG_B1452	3.683e-05	53.0	COG1390@1|root,COG1390@2|Bacteria,1VEEA@1239|Firmicutes,24QMH@186801|Clostridia,36J88@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
XH1_k127_5385359_6	1499967.BAYZ01000145_gene6196	1.305e-47	178.0	COG0636@1|root,COG0636@2|Bacteria,2NRTJ@2323|unclassified Bacteria	2|Bacteria	U	ATP synthase subunit C	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	-	ATP-synt_C
XH1_k127_5385359_4	1304874.JAFY01000007_gene2395	9.601e-69	260.0	COG1269@1|root,COG1269@2|Bacteria,3T9PG@508458|Synergistetes	508458|Synergistetes	U	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
XH1_k127_5385359_2	867903.ThesuDRAFT_02281	4.375e-109	362.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WCUJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
XH1_k127_5386659_4	986075.CathTA2_2625	2.286e-50	187.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli	91061|Bacilli	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02535	Thymidylate_kin
XH1_k127_5386659_0	459349.CLOAM0355	4.749e-103	355.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
XH1_k127_5386659_6	1191523.MROS_1840	1.935e-40	169.0	COG4359@1|root,COG4359@2|Bacteria	2|Bacteria	E	L-methionine salvage from methylthioadenosine	mtnX	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	HAD,Put_Phosphatase
XH1_k127_5386659_5	880073.Calab_0866	7.433e-44	171.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	luxD	-	3.2.1.4,4.2.99.18	ko:K01179,ko:K06889,ko:K10773,ko:K15853	ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko03400	-	GH5,GH9	-	Abhydrolase_1,Acyl_transf_2,DLH,Hydrolase_4,Peptidase_S9
XH1_k127_5386659_7	1191523.MROS_1441	3.47e-13	79.0	2AMSR@1|root,31CP7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5386659_3	243231.GSU1005	6.228e-78	273.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,43U4T@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
XH1_k127_5386659_1	138119.DSY1760	1.181e-81	278.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,260TX@186807|Peptococcaceae	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
XH1_k127_5386659_2	290397.Adeh_4313	2.59e-79	279.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,2YUS7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
XH1_k127_547766_4	69014.TK0650	2.176e-07	59.0	COG1633@1|root,arCOG01103@2157|Archaea,2Y1BE@28890|Euryarchaeota,243JF@183968|Thermococci	183968|Thermococci	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_547766_1	1121472.AQWN01000002_gene2175	1.75e-55	200.0	COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1V3CX@1239|Firmicutes,24IC2@186801|Clostridia,261SK@186807|Peptococcaceae	186801|Clostridia	C	PFAM Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
XH1_k127_547766_2	1121423.JONT01000006_gene2455	6.443e-30	123.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	perR	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
XH1_k127_547766_0	396588.Tgr7_2009	3.297e-58	212.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,1WXXG@135613|Chromatiales	135613|Chromatiales	L	PFAM HhH-GPD	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
XH1_k127_547766_3	309799.DICTH_1657	1.094e-23	102.0	COG0310@1|root,COG0310@2|Bacteria	2|Bacteria	P	cobalt ion transport	cbiM	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
XH1_k127_5558373_2	1047013.AQSP01000071_gene1939	1.467e-12	79.0	COG1297@1|root,COG1297@2|Bacteria,2NP0C@2323|unclassified Bacteria	2|Bacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
XH1_k127_5558373_0	720554.Clocl_2017	8.539e-57	208.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3WGKD@541000|Ruminococcaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
XH1_k127_5558373_3	1303518.CCALI_00376	0.0002916	46.0	COG0762@1|root,COG0762@2|Bacteria	2|Bacteria	D	integral membrane protein	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
XH1_k127_5558373_1	941824.TCEL_01772	9.861e-20	91.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,36FZ8@31979|Clostridiaceae	186801|Clostridia	D	PFAM DivIVA family protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
XH1_k127_5562104_1	1396141.BATP01000047_gene3903	7.868e-72	269.0	COG0457@1|root,COG3118@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG3379@2|Bacteria,46URB@74201|Verrucomicrobia,2IV4Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
XH1_k127_5562104_0	370438.PTH_0241	8.084e-145	469.0	COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,249ZJ@186801|Clostridia,26026@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
XH1_k127_5562104_2	237368.SCABRO_03144	9.907e-58	220.0	COG3379@1|root,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
XH1_k127_5573374_0	1191523.MROS_1530	2.761e-220	706.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
XH1_k127_5573374_2	485913.Krac_5497	3.109e-53	198.0	COG0384@1|root,COG0384@2|Bacteria,2G8NU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
XH1_k127_5573374_1	1380387.JADM01000009_gene3213	1.827e-56	207.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
XH1_k127_5576511_6	1125863.JAFN01000001_gene535	2.775e-40	162.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
XH1_k127_5576511_4	1379698.RBG1_1C00001G1249	1.472e-57	211.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
XH1_k127_5576511_0	269799.Gmet_0921	1.335e-72	256.0	COG1899@1|root,COG1899@2|Bacteria,1R3WQ@1224|Proteobacteria,42M57@68525|delta/epsilon subdivisions,2WJ6N@28221|Deltaproteobacteria,43RXI@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5576511_11	756272.Plabr_2158	5.676e-12	78.0	COG1287@1|root,COG1287@2|Bacteria,2J50Z@203682|Planctomycetes	203682|Planctomycetes	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_5576511_3	404589.Anae109_1412	2.116e-69	243.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
XH1_k127_5576511_7	909663.KI867150_gene2273	1.23e-26	120.0	COG1596@1|root,COG1596@2|Bacteria,1R6M3@1224|Proteobacteria,42SBA@68525|delta/epsilon subdivisions,2WPHA@28221|Deltaproteobacteria,2MS2V@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Polysaccharide biosynthesis export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
XH1_k127_5576511_10	483219.LILAB_03560	2.304e-13	83.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2YTU8@29|Myxococcales	28221|Deltaproteobacteria	D	protein involved in exopolysaccharide biosynthesis	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
XH1_k127_5576511_1	243231.GSU1982	3.676e-72	252.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42NNX@68525|delta/epsilon subdivisions,2WJ9P@28221|Deltaproteobacteria,43TQ5@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
XH1_k127_5576511_8	1348114.OM33_15980	1.328e-25	116.0	COG0489@1|root,COG0489@2|Bacteria,1MZ64@1224|Proteobacteria,1SCJB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	protein tyrosine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBP_BcsQ
XH1_k127_5576511_5	240016.ABIZ01000001_gene5365	4.129e-56	210.0	COG1524@1|root,COG1524@2|Bacteria,46XAN@74201|Verrucomicrobia,2IV7D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
XH1_k127_5576511_12	358396.C445_08177	2.041e-11	78.0	COG2244@1|root,arCOG02209@2157|Archaea,2XT90@28890|Euryarchaeota,23T02@183963|Halobacteria	183963|Halobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
XH1_k127_5576511_2	234267.Acid_7439	1.87e-69	251.0	COG1215@1|root,COG1215@2|Bacteria,3Y5K6@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH1_k127_5576511_9	1122216.AUHW01000001_gene767	7.999e-16	82.0	COG2076@1|root,COG2076@2|Bacteria,1VF8J@1239|Firmicutes,4H695@909932|Negativicutes	909932|Negativicutes	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	EamA
XH1_k127_5588164_0	639282.DEFDS_1228	9.577e-229	727.0	COG4799@1|root,COG4799@2|Bacteria,2GEP0@200930|Deferribacteres	200930|Deferribacteres	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
XH1_k127_5588164_1	273068.TTE1217	5.784e-198	627.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
XH1_k127_5603490_1	706587.Desti_5049	5.262e-57	212.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2MS09@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
XH1_k127_5603490_0	1123239.KB898623_gene1403	9.105e-106	355.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli	91061|Bacilli	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
XH1_k127_5619835_7	1209989.TepiRe1_1104	1.144e-26	111.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,24R29@186801|Clostridia,42GUA@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NifU
XH1_k127_5619835_1	518766.Rmar_0331	7.432e-93	319.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1FJUG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
XH1_k127_5619835_2	1379698.RBG1_1C00001G0370	4.718e-80	298.0	COG0616@1|root,COG0616@2|Bacteria,2NNKU@2323|unclassified Bacteria	2|Bacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
XH1_k127_5619835_0	880073.Calab_3525	6.54e-177	589.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
XH1_k127_5619835_3	880073.Calab_3524	2.707e-69	263.0	2CF1V@1|root,2Z8M1@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4876)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4876
XH1_k127_5619835_4	880073.Calab_3524	1.873e-54	216.0	2CF1V@1|root,2Z8M1@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4876)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4876
XH1_k127_5619835_6	1519464.HY22_04545	1.143e-28	134.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSII_BNR,fn3
XH1_k127_5619835_5	1210884.HG799469_gene14219	3.201e-36	148.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
XH1_k127_5685489_4	1379698.RBG1_1C00001G0723	5.318e-10	70.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
XH1_k127_5685489_0	1121468.AUBR01000008_gene2068	1.788e-52	189.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,42GC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
XH1_k127_5685489_2	340177.Cag_0887	3.538e-36	154.0	COG1765@1|root,COG1765@2|Bacteria,1FE41@1090|Chlorobi	1090|Chlorobi	O	PFAM OsmC family protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
XH1_k127_5685489_1	42256.RradSPS_0236	2.292e-47	181.0	COG0702@1|root,COG0702@2|Bacteria,2HM0H@201174|Actinobacteria,4CQ71@84995|Rubrobacteria	84995|Rubrobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
XH1_k127_5685489_3	880073.Calab_0921	8.199e-23	113.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
XH1_k127_569516_0	1207075.PputUW4_02827	1.436e-19	103.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_11,TPR_16,TPR_19,TPR_8
XH1_k127_5760059_0	316067.Geob_1222	0.0002596	52.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_5760325_11	521045.Kole_0569	1.889e-10	68.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
XH1_k127_5760325_0	521045.Kole_0568	6.09e-132	432.0	COG3261@1|root,COG3261@2|Bacteria	2|Bacteria	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_49kDa,NiFeSe_Hases
XH1_k127_5760325_1	338966.Ppro_3531	5.99e-113	387.0	COG1009@1|root,COG1009@2|Bacteria,1QV11@1224|Proteobacteria,43CGR@68525|delta/epsilon subdivisions,2X7RW@28221|Deltaproteobacteria	1224|Proteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
XH1_k127_5760325_9	326427.Cagg_2922	7.342e-16	85.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2G67I@200795|Chloroflexi,3770I@32061|Chloroflexia	32061|Chloroflexia	C	NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05565	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,Proton_antipo_M,Proton_antipo_N
XH1_k127_5760325_7	391623.TERMP_01350	3.097e-18	90.0	COG2111@1|root,arCOG03079@2157|Archaea,2XXHU@28890|Euryarchaeota,244DF@183968|Thermococci	183968|Thermococci	P	Multisubunit Na H antiporter	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
XH1_k127_5760325_6	391009.Tmel_1215	1.191e-21	98.0	COG1006@1|root,COG1006@2|Bacteria,2GDBG@200918|Thermotogae	200918|Thermotogae	P	oxidoreductase, chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
XH1_k127_5760325_2	521045.Kole_0565	3.864e-108	367.0	COG0651@1|root,COG0651@2|Bacteria,2GE49@200918|Thermotogae	200918|Thermotogae	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
XH1_k127_5760325_4	272844.PAB0485	2.077e-36	151.0	COG1863@1|root,arCOG03099@2157|Archaea,2XTHH@28890|Euryarchaeota,2430X@183968|Thermococci	183968|Thermococci	P	Na+/H+ ion antiporter subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
XH1_k127_5760325_10	272844.PAB3171	2.309e-14	81.0	COG2212@1|root,arCOG03121@2157|Archaea,2XZ7H@28890|Euryarchaeota,244HZ@183968|Thermococci	183968|Thermococci	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
XH1_k127_5760325_5	521045.Kole_0562	1.342e-31	128.0	COG1320@1|root,COG1320@2|Bacteria	2|Bacteria	P	monovalent cation:proton antiporter activity	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
XH1_k127_5760325_3	521045.Kole_0561	7.51e-39	152.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	ko:K12143	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Flavodoxin_5
XH1_k127_5760325_8	386456.JQKN01000002_gene2658	6.85e-17	87.0	COG0680@1|root,arCOG04429@2157|Archaea,2XXAF@28890|Euryarchaeota,23P79@183925|Methanobacteria	183925|Methanobacteria	C	hydrogenase maturation protease HycI	hycI	-	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
XH1_k127_5810091_0	1379698.RBG1_1C00001G0356	2.717e-110	387.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
XH1_k127_5810091_1	448385.sce7377	4.099e-91	319.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,2Z0DM@29|Myxococcales	28221|Deltaproteobacteria	M	RmlD substrate binding domain	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
XH1_k127_5810091_3	880073.Calab_1845	7.527e-88	317.0	COG0463@1|root,COG0463@2|Bacteria,2NP2G@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
XH1_k127_5810091_2	383372.Rcas_3942	1.289e-88	306.0	COG0438@1|root,COG0438@2|Bacteria,2G99J@200795|Chloroflexi,374RQ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
XH1_k127_5810091_4	351160.LRC548	2.799e-60	216.0	COG1216@1|root,arCOG01383@2157|Archaea,2XUCM@28890|Euryarchaeota,2NAQ3@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
XH1_k127_5834239_17	1158345.JNLL01000001_gene106	7.873e-27	116.0	COG0283@1|root,COG0283@2|Bacteria,2G3Z6@200783|Aquificae	200783|Aquificae	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
XH1_k127_5834239_7	574087.Acear_1028	4.244e-87	312.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3WA8M@53433|Halanaerobiales	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
XH1_k127_5834239_11	643648.Slip_1778	9.133e-55	209.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42JUR@68298|Syntrophomonadaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
XH1_k127_5834239_14	880073.Calab_3589	7.86e-42	162.0	COG1386@1|root,COG1386@2|Bacteria,2NPPM@2323|unclassified Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
XH1_k127_5834239_13	439235.Dalk_5224	1.097e-48	184.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,2MKHT@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
XH1_k127_5834239_8	457570.Nther_1668	8.78e-72	253.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
XH1_k127_5834239_3	767817.Desgi_4311	5.3e-156	512.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,260I5@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
XH1_k127_5834239_20	459349.CLOAM0933	1.563e-06	53.0	COG0268@1|root,COG0268@2|Bacteria	2|Bacteria	J	rRNA binding	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
XH1_k127_5834239_1	1232410.KI421428_gene1211	1.099e-183	592.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43RZR@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Aminoacyl-tRNA editing domain	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
XH1_k127_5834239_4	880073.Calab_2849	5.392e-155	526.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
XH1_k127_5834239_12	671143.DAMO_2317	1.349e-51	205.0	COG0253@1|root,COG0253@2|Bacteria,2NPFA@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0566,iLJ478.TM1522	DAP_epimerase
XH1_k127_5834239_19	309807.SRU_0507	1.518e-07	64.0	COG2372@1|root,COG2372@2|Bacteria,4PM5M@976|Bacteroidetes,1FIJV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CarboxypepD_reg
XH1_k127_5834239_6	880073.Calab_0179	2.089e-100	336.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
XH1_k127_5834239_9	247490.KSU1_C0574	2.753e-70	248.0	COG4974@1|root,COG4974@2|Bacteria,2IX6A@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
XH1_k127_5834239_10	909663.KI867149_gene3383	3.682e-59	210.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria,2MRIV@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Large-conductance mechanosensitive channel, MscL	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
XH1_k127_5834239_16	56780.SYN_02919	1.026e-36	147.0	COG0350@1|root,COG0500@1|root,COG0350@2|Bacteria,COG2226@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
XH1_k127_5834239_2	485913.Krac_3042	6.325e-182	590.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
XH1_k127_5834239_5	429009.Adeg_0573	2.527e-116	388.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,24971@186801|Clostridia,42ESP@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
XH1_k127_5834239_0	880073.Calab_0884	4.712e-233	743.0	COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
XH1_k127_5834239_21	349124.Hhal_2325	2.766e-05	52.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1WYZ6@135613|Chromatiales	135613|Chromatiales	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
XH1_k127_5834239_18	868595.Desca_2552	9.036e-11	62.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,260C9@186807|Peptococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
XH1_k127_5890689_0	880073.Calab_2402	1.047e-29	137.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5890689_1	1121930.AQXG01000004_gene2869	1.669e-16	94.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	prtA	-	3.2.1.23,3.4.24.40	ko:K01190,ko:K01406,ko:K07004,ko:K13277	ko00052,ko00511,ko00600,ko01100,ko01503,ko02024,map00052,map00511,map00600,map01100,map01503,map02024	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Gram_pos_anchor,HemolysinCabind,PA,Peptidase_S8,SLH,fn3_5
XH1_k127_594301_3	1379698.RBG1_1C00001G0340	2.727e-42	171.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
XH1_k127_594301_0	635013.TherJR_0848	1.286e-171	582.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,260F2@186807|Peptococcaceae	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
XH1_k127_594301_4	909663.KI867150_gene453	1.027e-06	55.0	COG0721@1|root,COG0721@2|Bacteria,1QE6H@1224|Proteobacteria,42VPR@68525|delta/epsilon subdivisions,2WRP0@28221|Deltaproteobacteria,2MQNA@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
XH1_k127_594301_1	1382304.JNIL01000001_gene2814	6.405e-157	509.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,2782N@186823|Alicyclobacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
XH1_k127_594301_2	289376.THEYE_A1151	4.903e-156	526.0	COG0064@1|root,COG0064@2|Bacteria,3J0FK@40117|Nitrospirae	40117|Nitrospirae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
XH1_k127_5943337_2	1267534.KB906756_gene100	3.173e-09	66.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria	2|Bacteria	D	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
XH1_k127_5943337_1	420662.Mpe_A1221	4.371e-19	102.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,2WF1B@28216|Betaproteobacteria,1KPKM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_5943337_0	459349.CLOAM1830	4.414e-25	121.0	COG4288@1|root,COG4288@2|Bacteria,2NRR9@2323|unclassified Bacteria	2|Bacteria	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Big_5,CHU_C,FlgD_ig,LTD
XH1_k127_59606_12	593750.Metfor_0426	8.145e-14	72.0	COG1117@1|root,arCOG00231@2157|Archaea,2XTJK@28890|Euryarchaeota,2N93D@224756|Methanomicrobia	28890|Euryarchaeota	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
XH1_k127_59606_3	935845.JADQ01000029_gene1230	7.169e-152	507.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
XH1_k127_59606_11	459349.CLOAM0442	2.316e-19	104.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
XH1_k127_59606_5	36875.HQ29_01355	2.139e-105	349.0	COG0543@1|root,COG0543@2|Bacteria,4NJ0I@976|Bacteroidetes,2FNBW@200643|Bacteroidia,22WH8@171551|Porphyromonadaceae	976|Bacteroidetes	C	Ferredoxin-NADP reductase	gltD	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
XH1_k127_59606_1	573413.Spirs_1641	3.607e-192	610.0	COG0493@1|root,COG0493@2|Bacteria,2J5FP@203691|Spirochaetes	203691|Spirochaetes	C	glutamate synthase (NADPH), homotetrameric	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
XH1_k127_59606_2	177437.HRM2_09160	1.147e-171	556.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2WJ5J@28221|Deltaproteobacteria,2MHQP@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
XH1_k127_59606_4	1408473.JHXO01000005_gene1613	1.792e-147	478.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes	976|Bacteroidetes	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
XH1_k127_59606_6	452637.Oter_4531	6.695e-103	372.0	COG4805@1|root,COG4805@2|Bacteria,46T5D@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
XH1_k127_59606_9	350688.Clos_2542	2.25e-34	140.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia,36EYH@31979|Clostridiaceae	186801|Clostridia	S	MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	ACT,ACT_4,MgtC
XH1_k127_59606_0	243231.GSU0306	6.012e-205	663.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2WJ51@28221|Deltaproteobacteria,43S2B@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	iAF987.Gmet_0119	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
XH1_k127_59606_7	886293.Sinac_4491	6.773e-99	361.0	COG0309@1|root,COG0309@2|Bacteria,2IX50@203682|Planctomycetes	203682|Planctomycetes	O	AIR synthase related protein, C-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
XH1_k127_59606_8	1121346.KB899814_gene1754	2.157e-59	215.0	COG1387@1|root,COG1387@2|Bacteria,1UZ0M@1239|Firmicutes,4IQT7@91061|Bacilli,26RD1@186822|Paenibacillaceae	91061|Bacilli	E	Histidinol phosphatase	hisJ1	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
XH1_k127_59606_10	1460635.JCM19038_615	3.409e-22	98.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli	91061|Bacilli	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
XH1_k127_6033142_10	1121918.ARWE01000001_gene2861	3.56e-10	65.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
XH1_k127_6033142_11	269799.Gmet_0758	1.036e-09	69.0	2DYZ6@1|root,34BUY@2|Bacteria,1QRAA@1224|Proteobacteria,43EY0@68525|delta/epsilon subdivisions,2XA12@28221|Deltaproteobacteria,43VMW@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6033142_8	243231.GSU1085	2.046e-22	110.0	2CEWP@1|root,33R6D@2|Bacteria,1NT52@1224|Proteobacteria,42Y56@68525|delta/epsilon subdivisions,2WUQX@28221|Deltaproteobacteria,43TA6@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6033142_14	338966.Ppro_2819	4.574e-07	60.0	2FE06@1|root,3460D@2|Bacteria,1NX4R@1224|Proteobacteria,430S9@68525|delta/epsilon subdivisions,2WW3K@28221|Deltaproteobacteria,43V5P@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6033142_12	645991.Sgly_1081	2.106e-09	63.0	COG1040@1|root,COG1040@2|Bacteria,1VEST@1239|Firmicutes,25I5J@186801|Clostridia,2669D@186807|Peptococcaceae	186801|Clostridia	S	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
XH1_k127_6033142_2	269799.Gmet_0754	7.067e-98	329.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,43UZT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,DZR,SHOCT,zinc_ribbon_2
XH1_k127_6033142_13	391623.TERMP_01760	7.83e-09	64.0	arCOG03769@1|root,arCOG03769@2157|Archaea,2Y3V9@28890|Euryarchaeota,245JM@183968|Thermococci	183968|Thermococci	M	glucosylceramidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6033142_5	877455.Metbo_0860	6.591e-70	259.0	COG0726@1|root,arCOG02878@2157|Archaea	2157|Archaea	G	deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
XH1_k127_6033142_3	877455.Metbo_0861	1.854e-91	322.0	COG1541@1|root,arCOG02624@2157|Archaea,2XY74@28890|Euryarchaeota	28890|Euryarchaeota	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
XH1_k127_6033142_9	111105.HR09_08945	9.418e-16	91.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,2FSH0@200643|Bacteroidia,22XW8@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
XH1_k127_6033142_7	582515.KR51_00012600	3.997e-29	129.0	COG0853@1|root,COG0853@2|Bacteria,1G6IZ@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Asp_decarbox
XH1_k127_6033142_4	243164.DET0769	4.516e-77	274.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,34D00@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
XH1_k127_6033142_6	156889.Mmc1_2110	7.77e-63	231.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria	1224|Proteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
XH1_k127_6033142_0	880073.Calab_3036	3.228e-223	713.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
XH1_k127_6033142_1	927658.AJUM01000043_gene687	2.214e-141	464.0	COG2271@1|root,COG2271@2|Bacteria,4PKTC@976|Bacteroidetes,2G3HT@200643|Bacteroidia	976|Bacteroidetes	G	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
XH1_k127_6041629_0	1519464.HY22_06985	1.49e-54	216.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1FENS@1090|Chlorobi	1090|Chlorobi	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,SpoIIE
XH1_k127_6058972_0	1089550.ATTH01000001_gene2240	8.199e-132	443.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1FJ5H@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
XH1_k127_6058972_1	562970.Btus_1620	6.449e-96	331.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,27851@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
XH1_k127_6063739_2	1047013.AQSP01000130_gene1866	7.701e-117	382.0	COG0591@1|root,COG0591@2|Bacteria,2NR5Z@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
XH1_k127_6063739_0	1191523.MROS_1594	2.55e-316	1004.0	COG3537@1|root,COG3537@2|Bacteria	2|Bacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
XH1_k127_6063739_1	1168289.AJKI01000053_gene794	4.857e-231	744.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,2FN2H@200643|Bacteroidia,3XKNS@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
XH1_k127_6063739_3	304371.MCP_1916	4.509e-83	284.0	COG1145@1|root,arCOG00296@2157|Archaea,2XUE5@28890|Euryarchaeota	28890|Euryarchaeota	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_21,Fer4_9
XH1_k127_6134715_7	945713.IALB_3074	3.856e-10	74.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin,Thioredoxin_2,Thioredoxin_9
XH1_k127_6134715_0	1047013.AQSP01000105_gene1461	9.984e-231	750.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	dap2	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
XH1_k127_6134715_5	1121859.KB890750_gene187	1.473e-28	123.0	COG2143@1|root,COG2143@2|Bacteria,4NM6B@976|Bacteroidetes,47Q2D@768503|Cytophagia	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
XH1_k127_6134715_2	56780.SYN_00886	1.276e-92	316.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,2MQH8@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Phosphofructokinase	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
XH1_k127_6134715_4	436114.SYO3AOP1_0232	7.339e-58	215.0	COG2265@1|root,COG2265@2|Bacteria,2G3V7@200783|Aquificae	200783|Aquificae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
XH1_k127_6134715_3	1227487.C474_07822	7.527e-70	258.0	COG0438@1|root,arCOG01410@2157|Archaea,2XV5R@28890|Euryarchaeota,23USK@183963|Halobacteria	183963|Halobacteria	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
XH1_k127_6134715_1	926550.CLDAP_40360	2.099e-129	423.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
XH1_k127_6134715_6	290318.Cvib_0237	5.503e-23	115.0	COG0438@1|root,COG0438@2|Bacteria,1FE7C@1090|Chlorobi	1090|Chlorobi	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
XH1_k127_6151691_1	4432.XP_010276986.1	1.453e-32	145.0	COG4870@1|root,KOG1543@2759|Eukaryota,37TGB@33090|Viridiplantae,3GFEW@35493|Streptophyta	33090|Viridiplantae	O	Belongs to the peptidase C1 family	-	-	-	ko:K16290	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Inhibitor_I29,Peptidase_C1
XH1_k127_6151691_0	880073.Calab_0470	1.257e-63	237.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
XH1_k127_6263692_1	1122176.KB903619_gene5465	1.365e-63	222.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1IQNN@117747|Sphingobacteriia	976|Bacteroidetes	E	Alanine dehydrogenase/PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
XH1_k127_6263692_0	314278.NB231_13711	7.64e-153	491.0	COG1373@1|root,COG1373@2|Bacteria,1RAB0@1224|Proteobacteria,1SA91@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
XH1_k127_6275604_1	1121472.AQWN01000007_gene1144	1.36e-42	160.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
XH1_k127_6275604_3	215803.DB30_2177	5.058e-12	79.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
XH1_k127_6275604_2	1379270.AUXF01000006_gene26	3.651e-15	89.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
XH1_k127_6275604_0	767817.Desgi_1888	1.995e-55	204.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,26144@186807|Peptococcaceae	186801|Clostridia	S	PFAM PHP domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
XH1_k127_6281347_0	574556.ACIS_00384	1.775e-25	111.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N,YjbR
XH1_k127_6281347_1	1410628.JNKS01000014_gene418	5.39e-13	82.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,27ISD@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
XH1_k127_6360111_0	592015.HMPREF1705_01676	1.317e-113	396.0	COG4690@1|root,COG4690@2|Bacteria,3TBIE@508458|Synergistetes	508458|Synergistetes	M	Dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
XH1_k127_6360111_6	502025.Hoch_4133	2.351e-15	91.0	COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,434NC@68525|delta/epsilon subdivisions,2WYZN@28221|Deltaproteobacteria,2Z10G@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
XH1_k127_6360111_7	330214.NIDE2862	1.343e-10	71.0	2EGPU@1|root,33AFZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6360111_2	439235.Dalk_1881	9.868e-48	190.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_6360111_9	1123059.KB823014_gene36	4.145e-05	57.0	29A93@1|root,33K0N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
XH1_k127_6360111_1	323259.Mhun_2469	2.926e-65	244.0	arCOG02322@1|root,arCOG02322@2157|Archaea,2Y48R@28890|Euryarchaeota,2NB1V@224756|Methanomicrobia	2157|Archaea	N	HAMP domain	-	-	2.7.13.3	ko:K03406,ko:K07652	ko02020,ko02030,map02020,map02030	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,MCPsignal,PAS_9,dCache_3,sCache_3_3
XH1_k127_6360111_8	323259.Mhun_2468	6.998e-09	61.0	arCOG09502@1|root,arCOG09502@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6360111_3	880073.Calab_3539	3.456e-37	153.0	COG0589@1|root,COG0589@2|Bacteria,2NPUM@2323|unclassified Bacteria	2|Bacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
XH1_k127_6360111_4	1191523.MROS_1662	3.229e-28	125.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	-	R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
XH1_k127_6360111_5	1121918.ARWE01000001_gene2861	1.97e-16	87.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
XH1_k127_6360144_0	1121918.ARWE01000001_gene2861	5.327e-16	86.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
XH1_k127_6360144_2	671143.DAMO_0301	0.0003434	53.0	COG0457@1|root,COG4745@1|root,COG0457@2|Bacteria,COG4745@2|Bacteria,2NQJ6@2323|unclassified Bacteria	2|Bacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2,TPR_2,TPR_8
XH1_k127_6360144_1	266940.Krad_1503	2.415e-07	58.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria	201174|Actinobacteria	KT	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
XH1_k127_6407045_1	479434.Sthe_2092	8.664e-29	135.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.1.11.5,3.1.12.1,3.6.4.12	ko:K01144,ko:K07464,ko:K16898	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
XH1_k127_6407045_0	479434.Sthe_2091	2.776e-72	273.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
XH1_k127_648158_2	1519464.HY22_09070	2.359e-93	341.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	pepN1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
XH1_k127_648158_4	1128421.JAGA01000002_gene1359	1.146e-78	297.0	COG0520@1|root,COG0520@2|Bacteria,2NP4B@2323|unclassified Bacteria	2|Bacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
XH1_k127_648158_6	1191523.MROS_0653	3.723e-39	168.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
XH1_k127_648158_1	639030.JHVA01000001_gene1760	3.543e-132	446.0	COG0312@1|root,COG0312@2|Bacteria,3Y2TY@57723|Acidobacteria,2JI8B@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
XH1_k127_648158_3	292415.Tbd_2148	1.063e-79	282.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,1KRIB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
XH1_k127_648158_8	1267211.KI669560_gene104	1.058e-21	111.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IPFH@117747|Sphingobacteriia	976|Bacteroidetes	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
XH1_k127_648158_0	945713.IALB_3149	4.878e-146	476.0	COG1236@1|root,COG1236@2|Bacteria	2|Bacteria	J	nucleic acid phosphodiester bond hydrolysis	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
XH1_k127_648158_5	314278.NB231_10363	1.502e-58	216.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,1RRYH@1236|Gammaproteobacteria,1X059@135613|Chromatiales	135613|Chromatiales	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
XH1_k127_648158_9	298653.Franean1_0594	9.069e-08	57.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
XH1_k127_648158_7	335541.Swol_0058	1.161e-34	141.0	COG0438@1|root,COG0438@2|Bacteria,1TQ1S@1239|Firmicutes,24GPH@186801|Clostridia	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
XH1_k127_6541475_1	370438.PTH_1803	2.286e-31	135.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,2615B@186807|Peptococcaceae	186801|Clostridia	K	Fibronectin-binding protein A N-terminus (FbpA)	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
XH1_k127_6541475_0	525897.Dbac_0935	3.635e-70	245.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2WJJ4@28221|Deltaproteobacteria,2M8I8@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
XH1_k127_6559266_2	1191523.MROS_0247	6.163e-46	168.0	COG3304@1|root,COG3304@2|Bacteria	2|Bacteria	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
XH1_k127_6559266_0	1499967.BAYZ01000137_gene110	4.376e-79	276.0	COG1600@1|root,COG1600@2|Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Fer4_16
XH1_k127_6559266_9	1248760.ANFZ01000006_gene2315	0.0001227	51.0	COG4308@1|root,COG4308@2|Bacteria,1PNKX@1224|Proteobacteria,2V16P@28211|Alphaproteobacteria,2K79C@204457|Sphingomonadales	204457|Sphingomonadales	Q	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	LEH
XH1_k127_6559266_6	477228.YO5_10035	8.807e-26	115.0	COG4273@1|root,COG4273@2|Bacteria,1MZN7@1224|Proteobacteria,1SRY2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF2703)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2703
XH1_k127_6559266_1	395961.Cyan7425_0454	3.031e-78	265.0	COG3153@1|root,COG3153@2|Bacteria,1GK4X@1117|Cyanobacteria,3KIFY@43988|Cyanothece	1117|Cyanobacteria	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
XH1_k127_6559266_4	1496688.ER33_07400	9.873e-42	160.0	COG1917@1|root,COG1917@2|Bacteria,1GFV0@1117|Cyanobacteria	1117|Cyanobacteria	S	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6559266_3	269799.Gmet_2503	2.425e-45	166.0	COG2337@1|root,COG2337@2|Bacteria,1N0JV@1224|Proteobacteria,42STH@68525|delta/epsilon subdivisions,2WP6X@28221|Deltaproteobacteria,43VCI@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
XH1_k127_6559266_7	768710.DesyoDRAFT_4910	3.77e-12	70.0	COG2336@1|root,COG2336@2|Bacteria,1W2UC@1239|Firmicutes	1239|Firmicutes	K	SpoVT / AbrB like domain	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
XH1_k127_656490_4	595460.RRSWK_05520	9.92e-71	252.0	COG2304@1|root,COG2304@2|Bacteria,2IYWC@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
XH1_k127_656490_7	1379698.RBG1_1C00001G1774	1.05e-62	237.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
XH1_k127_656490_19	880073.Calab_2476	1.488e-11	78.0	COG0457@1|root,COG0457@2|Bacteria,2NRZ3@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1
XH1_k127_656490_9	313628.LNTAR_05446	4.003e-44	181.0	COG0457@1|root,COG0457@2|Bacteria	313628.LNTAR_05446|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_656490_17	1232437.KL661999_gene4709	1.566e-13	81.0	COG4783@1|root,COG4783@2|Bacteria,1QTUQ@1224|Proteobacteria,43CMK@68525|delta/epsilon subdivisions,2X8EH@28221|Deltaproteobacteria,2MPP1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
XH1_k127_656490_2	272559.BF9343_1980	2.013e-115	391.0	COG3579@1|root,COG3579@2|Bacteria,4NJ3J@976|Bacteroidetes,2FMZY@200643|Bacteroidia,4AM6R@815|Bacteroidaceae	976|Bacteroidetes	E	Peptidase C1-like family	pepC	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
XH1_k127_656490_5	555088.DealDRAFT_2075	1.131e-65	233.0	arCOG03165@1|root,30AIC@2|Bacteria,1V7NB@1239|Firmicutes,24M5X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_656490_18	224325.AF_1164	2.783e-12	78.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota,24612@183980|Archaeoglobi	183980|Archaeoglobi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
XH1_k127_656490_3	1499967.BAYZ01000009_gene5286	1.245e-88	317.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
XH1_k127_656490_15	1499967.BAYZ01000009_gene5287	6.123e-19	94.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	-	ATP-synt_C
XH1_k127_656490_12	1123274.KB899427_gene3356	6.704e-26	110.0	COG1436@1|root,COG1436@2|Bacteria,2J8AJ@203691|Spirochaetes	203691|Spirochaetes	C	-ATPase subunit F	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
XH1_k127_656490_16	246969.TAM4_1195	2.295e-14	84.0	COG1390@1|root,arCOG00869@2157|Archaea,2XWGX@28890|Euryarchaeota,243A6@183968|Thermococci	183968|Thermococci	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
XH1_k127_656490_0	158189.SpiBuddy_1148	2.019e-246	773.0	COG1155@1|root,COG1155@2|Bacteria,2J5EF@203691|Spirochaetes	203691|Spirochaetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
XH1_k127_656490_1	573413.Spirs_3107	8.983e-210	660.0	COG1156@1|root,COG1156@2|Bacteria,2J5SP@203691|Spirochaetes	203691|Spirochaetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
XH1_k127_656490_8	573413.Spirs_3106	2.27e-52	192.0	COG1394@1|root,COG1394@2|Bacteria,2J5V1@203691|Spirochaetes	203691|Spirochaetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
XH1_k127_656490_13	545695.TREAZ_3416	9.639e-24	110.0	COG0589@1|root,COG0589@2|Bacteria,2J7EV@203691|Spirochaetes	203691|Spirochaetes	T	universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
XH1_k127_656490_11	880073.Calab_1794	4.067e-33	136.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
XH1_k127_656490_10	1167006.UWK_02094	3.183e-42	165.0	2CK5J@1|root,34791@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_656490_6	1449126.JQKL01000009_gene356	2.44e-65	229.0	COG1924@1|root,COG1924@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
XH1_k127_656490_14	670487.Ocepr_2151	1.268e-21	102.0	COG1268@1|root,COG1268@2|Bacteria,1WJ9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM BioY protein	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
XH1_k127_6585213_3	1121104.AQXH01000001_gene1542	1.818e-31	129.0	COG0793@1|root,COG0793@2|Bacteria,4NM82@976|Bacteroidetes	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N,TPR_2
XH1_k127_6585213_2	1121439.dsat_1515	1.609e-48	183.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,42PPN@68525|delta/epsilon subdivisions,2WK8S@28221|Deltaproteobacteria,2M7WI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
XH1_k127_6585213_4	861299.J421_6107	1.027e-22	103.0	2CIH2@1|root,2ZTG0@2|Bacteria	2|Bacteria	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
XH1_k127_6585213_1	509191.AEDB02000003_gene999	2.711e-93	314.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,25CI8@186801|Clostridia,3WJ6E@541000|Ruminococcaceae	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
XH1_k127_6585213_0	644966.Tmar_0732	1.347e-120	394.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252,ko:K18244	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_6589845_3	635013.TherJR_1781	1.994e-57	203.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,260I8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
XH1_k127_6589845_4	1121405.dsmv_1590	4.924e-49	181.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,2MJM4@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
XH1_k127_6589845_1	555079.Toce_1695	3.98e-84	293.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
XH1_k127_6589845_0	644966.Tmar_0955	1.089e-87	299.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3WCG9@538999|Clostridiales incertae sedis	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
XH1_k127_6589845_5	338963.Pcar_2483	2.834e-38	147.0	COG0730@1|root,COG0730@2|Bacteria,1PD7F@1224|Proteobacteria,42TC8@68525|delta/epsilon subdivisions,2WPFJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
XH1_k127_6589845_2	404380.Gbem_0962	1.209e-75	283.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,43T01@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
XH1_k127_6591830_2	1336243.JAEA01000013_gene3245	6.77e-09	62.0	COG2091@1|root,COG2091@2|Bacteria,1MZHC@1224|Proteobacteria,2UFA4@28211|Alphaproteobacteria,1JUQM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
XH1_k127_6591830_0	756067.MicvaDRAFT_2506	4.095e-262	856.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H9T8@1150|Oscillatoriales	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
XH1_k127_6591830_1	370438.PTH_1859	7.11e-63	231.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,261EW@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
XH1_k127_661356_1	204669.Acid345_1213	1.874e-34	136.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria,2JIRS@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
XH1_k127_661356_2	330214.NIDE1608	2.605e-14	87.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
XH1_k127_661356_0	266117.Rxyl_2626	2.369e-108	365.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4CTCM@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
XH1_k127_6631904_2	945713.IALB_3164	5.034e-177	576.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
XH1_k127_6631904_0	335543.Sfum_4019	8.904e-292	902.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MSIG@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
XH1_k127_6631904_1	349521.HCH_01823	8.332e-186	593.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1XI4B@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
XH1_k127_6631904_9	56780.SYN_01756	3.168e-08	66.0	COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria	1224|Proteobacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX_N
XH1_k127_6631904_3	497965.Cyan7822_3560	9.215e-66	256.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,3KGI4@43988|Cyanothece	1117|Cyanobacteria	N	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_8
XH1_k127_6631904_8	1144275.COCOR_05366	9.863e-15	81.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6631904_6	945713.IALB_0843	1.021e-17	100.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
XH1_k127_6631904_4	1379698.RBG1_1C00001G1218	3.02e-61	233.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
XH1_k127_6631904_10	118166.JH976538_gene5205	0.0001942	53.0	COG0457@1|root,COG0457@2|Bacteria,1G5S0@1117|Cyanobacteria,1HC37@1150|Oscillatoriales	1117|Cyanobacteria	S	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6631904_5	4533.OB09G26480.1	1.378e-34	152.0	COG4870@1|root,KOG1543@2759|Eukaryota	2759|Eukaryota	O	cysteine-type peptidase activity	-	-	3.4.22.1,3.4.22.15,3.4.22.16	ko:K01363,ko:K01365,ko:K01366,ko:K16290,ko:K16292	ko04140,ko04142,ko04145,ko04210,ko04612,ko04621,ko04924,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map04621,map04924,map05205,map05323,map05418	-	-	-	ko00000,ko00001,ko00536,ko00537,ko01000,ko01002,ko03110,ko04147	-	-	-	Granulin,Inhibitor_I29,Peptidase_C1
XH1_k127_6631904_7	459349.CLOAM1790	8.493e-16	91.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
XH1_k127_6676288_0	1379270.AUXF01000004_gene3060	7.332e-63	222.0	COG3367@1|root,COG3367@2|Bacteria,1ZUM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
XH1_k127_6676288_2	1242864.D187_003382	5.42e-29	128.0	COG1468@1|root,COG1468@2|Bacteria	2|Bacteria	L	DNA catabolic process, exonucleolytic	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779,PDDEXK_1
XH1_k127_6676288_3	867903.ThesuDRAFT_02310	1.602e-24	108.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
XH1_k127_6676288_1	882.DVU_3097	8.205e-34	145.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2WKMG@28221|Deltaproteobacteria,2M7UB@213115|Desulfovibrionales	28221|Deltaproteobacteria	MU	outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
XH1_k127_6682387_1	459349.CLOAM1790	6.411e-27	113.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
XH1_k127_6682387_0	204669.Acid345_1052	4.046e-124	427.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
XH1_k127_6686518_2	1242864.D187_005740	8.103e-28	124.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,43BTG@68525|delta/epsilon subdivisions,2X74B@28221|Deltaproteobacteria,2Z3ED@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
XH1_k127_6686518_1	1121423.JONT01000015_gene1306	1.323e-73	257.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,260CA@186807|Peptococcaceae	186801|Clostridia	S	pfam psp1	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
XH1_k127_6686518_0	760568.Desku_0043	1.897e-144	486.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,2613N@186807|Peptococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
XH1_k127_6738600_0	439235.Dalk_4220	3.315e-18	95.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1RAHZ@1224|Proteobacteria,42UGY@68525|delta/epsilon subdivisions,2WQPI@28221|Deltaproteobacteria,2MNGQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
XH1_k127_679471_19	1121430.JMLG01000001_gene2115	2.025e-12	77.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,261QR@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
XH1_k127_679471_1	861299.J421_3561	1.073e-255	805.0	COG0556@1|root,COG0556@2|Bacteria,1ZSQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
XH1_k127_679471_6	1502851.FG93_01759	2.746e-62	224.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,3JSBS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
XH1_k127_679471_10	1501230.ET33_36360	3.088e-40	167.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26QTA@186822|Paenibacillaceae	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
XH1_k127_679471_16	1110502.TMO_1963	6.429e-18	94.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2TS5A@28211|Alphaproteobacteria,2JPNZ@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
XH1_k127_679471_13	1379698.RBG1_1C00001G0288	3.624e-34	133.0	COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
XH1_k127_679471_2	1191523.MROS_2693	8.999e-234	734.0	COG0459@1|root,COG0459@2|Bacteria	2|Bacteria	O	protein refolding	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
XH1_k127_679471_3	1123371.ATXH01000022_gene959	5.661e-105	357.0	COG0436@1|root,COG0436@2|Bacteria,2GGY5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
XH1_k127_679471_17	927704.SELR_27260	1.078e-16	91.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4H54R@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
XH1_k127_679471_14	264732.Moth_0139	4.061e-31	129.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,42GWU@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
XH1_k127_679471_7	404589.Anae109_3810	1.029e-61	219.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria	1224|Proteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
XH1_k127_679471_4	580331.Thit_0447	3.299e-95	330.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,42FEE@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
XH1_k127_679471_5	264732.Moth_0141	1.857e-77	279.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,42F66@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
XH1_k127_679471_8	525897.Dbac_1462	1.083e-43	167.0	COG0537@1|root,COG0537@2|Bacteria,1RHYQ@1224|Proteobacteria,42SEG@68525|delta/epsilon subdivisions,2WPFW@28221|Deltaproteobacteria,2MB1T@213115|Desulfovibrionales	28221|Deltaproteobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	CwfJ_C_1,HIT
XH1_k127_679471_21	545694.TREPR_3453	2.267e-08	61.0	COG1316@1|root,COG1316@2|Bacteria,2J57I@203691|Spirochaetes	203691|Spirochaetes	K	PFAM Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
XH1_k127_679471_20	1313301.AUGC01000006_gene169	8.931e-09	63.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
XH1_k127_679471_11	945713.IALB_2343	8.234e-38	162.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	ppiD	-	5.2.1.8	ko:K01802,ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3
XH1_k127_679471_9	880073.Calab_1320	4.647e-43	179.0	COG0739@1|root,COG0739@2|Bacteria,2NR6F@2323|unclassified Bacteria	2|Bacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
XH1_k127_679471_0	1379698.RBG1_1C00001G0460	4.4e-323	1024.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
XH1_k127_679471_12	1519464.HY22_04580	3.393e-34	143.0	2CBA8@1|root,30BZT@2|Bacteria,1FEGZ@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_679471_18	760142.Hipma_0205	5.769e-16	79.0	COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria,2M7FV@213113|Desulfurellales	28221|Deltaproteobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
XH1_k127_679471_15	1379698.RBG1_1C00001G1789	1.811e-30	140.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
XH1_k127_687396_2	518766.Rmar_0713	3.177e-10	70.0	2EGU2@1|root,33AK8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_687396_1	243231.GSU1864	2.095e-43	181.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,43UBJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
XH1_k127_687396_0	1121918.ARWE01000001_gene1254	1.612e-102	350.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43S50@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
XH1_k127_6882255_0	1499967.BAYZ01000119_gene3214	1.471e-93	316.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
XH1_k127_6882255_1	429009.Adeg_0423	3.544e-67	237.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
XH1_k127_6883657_6	314345.SPV1_05347	4.039e-25	110.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
XH1_k127_6883657_2	118005.AWNK01000001_gene1858	4.736e-48	185.0	COG0603@1|root,COG0603@2|Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
XH1_k127_6883657_4	429009.Adeg_0592	2.091e-32	141.0	COG2029@1|root,COG2029@2|Bacteria,1V5P0@1239|Firmicutes,24IRW@186801|Clostridia,42GR7@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF366)	-	-	-	ko:K09139	-	-	-	-	ko00000	-	-	-	DUF366
XH1_k127_6883657_3	927704.SELR_20800	1.448e-41	172.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4H3BM@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
XH1_k127_6883657_5	1379698.RBG1_1C00001G1143	7.991e-29	118.0	COG0776@1|root,COG0776@2|Bacteria,2NPU6@2323|unclassified Bacteria	2|Bacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup_1	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
XH1_k127_6883657_0	880073.Calab_2912	1.152e-95	325.0	COG2008@1|root,COG2008@2|Bacteria,2NNMP@2323|unclassified Bacteria	2|Bacteria	E	aromatic amino acid beta-eliminating lyase threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
XH1_k127_6883657_1	1110502.TMO_3467	3.918e-62	222.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,2JQFJ@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
XH1_k127_6908044_1	96561.Dole_0808	1.828e-96	331.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria,2MMZK@213118|Desulfobacterales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_6908044_2	96561.Dole_0807	1.034e-86	296.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM secretion protein HlyD family protein	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
XH1_k127_6908044_0	671143.DAMO_2750	6.639e-180	592.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2NNNK@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase X family	polX	-	-	ko:K02347,ko:K04477	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
XH1_k127_6908044_3	1318628.MARLIPOL_10651	8.439e-35	138.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,468FQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
XH1_k127_6908044_5	1122947.FR7_4244	2.927e-21	101.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,4H5CS@909932|Negativicutes	909932|Negativicutes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
XH1_k127_6908044_4	484770.UFO1_2322	2.124e-31	127.0	COG0739@1|root,COG0739@2|Bacteria,1TRWJ@1239|Firmicutes	1239|Firmicutes	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
XH1_k127_6916872_7	1379698.RBG1_1C00001G0356	4.826e-09	59.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
XH1_k127_6916872_5	489825.LYNGBM3L_22570	7.488e-31	141.0	COG0392@1|root,COG0392@2|Bacteria,1G41A@1117|Cyanobacteria,1HD8Q@1150|Oscillatoriales	1117|Cyanobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
XH1_k127_6916872_1	1379698.RBG1_1C00001G1319	6.812e-103	347.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
XH1_k127_6916872_2	59374.Fisuc_0695	7.075e-58	210.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
XH1_k127_6916872_4	648996.Theam_0490	1.668e-39	161.0	COG0639@1|root,COG0639@2|Bacteria,2G41R@200783|Aquificae	200783|Aquificae	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
XH1_k127_6916872_6	1379698.RBG1_1C00001G1320	1.259e-22	102.0	COG0781@1|root,COG0781@2|Bacteria,2NPZI@2323|unclassified Bacteria	2|Bacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
XH1_k127_6916872_3	1191523.MROS_1962	3.864e-46	176.0	COG0054@1|root,COG0054@2|Bacteria	2|Bacteria	H	6,7-dimethyl-8-ribityllumazine synthase activity	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1825,iSB619.SA_RS08940,iSFV_1184.SFV_0380	DMRL_synthase
XH1_k127_6916872_0	429009.Adeg_1980	1.623e-118	386.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,42FC2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
XH1_k127_6923047_4	555079.Toce_2275	2.951e-63	241.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,42FPF@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
XH1_k127_6923047_1	1430331.EP10_00955	4.677e-95	320.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1WF4W@129337|Geobacillus	91061|Bacilli	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
XH1_k127_6923047_6	1144275.COCOR_04227	3.378e-07	63.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria,2YZ03@29|Myxococcales	28221|Deltaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,PKD
XH1_k127_6923047_0	1232410.KI421422_gene2039	3.381e-190	623.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria,43TF6@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
XH1_k127_6923047_2	1121472.AQWN01000012_gene924	1.903e-89	311.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,260CJ@186807|Peptococcaceae	186801|Clostridia	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
XH1_k127_6923047_5	1121430.JMLG01000002_gene1319	1.846e-34	141.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,260UK@186807|Peptococcaceae	186801|Clostridia	S	PFAM Single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
XH1_k127_6923047_3	177437.HRM2_06670	8.124e-71	259.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2MJ96@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
XH1_k127_6925527_2	1379698.RBG1_1C00001G0315	1.46e-38	166.0	COG4942@1|root,COG4942@2|Bacteria,2NPDY@2323|unclassified Bacteria	2|Bacteria	D	Peptidase family M23	envC	GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
XH1_k127_6925527_4	1120985.AUMI01000014_gene860	2.688e-34	151.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4H36P@909932|Negativicutes	909932|Negativicutes	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
XH1_k127_6925527_1	880073.Calab_1944	7.366e-65	230.0	COG2884@1|root,COG2884@2|Bacteria,2NP95@2323|unclassified Bacteria	2|Bacteria	D	ATPases associated with a variety of cellular activities	ftsE	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
XH1_k127_6925527_0	518766.Rmar_1652	1.679e-66	241.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1FIZN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
XH1_k127_6925527_8	459349.CLOAM0180	6.273e-10	71.0	COG1188@1|root,COG1188@2|Bacteria,2NQ1V@2323|unclassified Bacteria	2|Bacteria	J	S4 RNA-binding domain	yabO	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	DUF3558,S4
XH1_k127_6925527_3	517418.Ctha_0311	3.672e-35	155.0	COG0760@1|root,COG0760@2|Bacteria,1FDC8@1090|Chlorobi	1090|Chlorobi	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N,SurA_N_3
XH1_k127_6925527_5	443143.GM18_0166	2.162e-28	126.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,43T4C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
XH1_k127_6925527_7	1283300.ATXB01000001_gene2338	5.632e-11	76.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1SB9C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
XH1_k127_6925527_6	575609.HMPREF0629_00981	3.813e-22	112.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,22HEE@1570339|Peptoniphilaceae	186801|Clostridia	O	Peptidylprolyl isomerase	prsA2	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
XH1_k127_6935151_2	408672.NBCG_02242	0.0005888	46.0	COG1524@1|root,COG1524@2|Bacteria,2HY6Q@201174|Actinobacteria,4DT1Q@85009|Propionibacteriales	201174|Actinobacteria	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
XH1_k127_6935151_1	1348663.KCH_09230	0.0002621	54.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,2M3EI@2063|Kitasatospora	201174|Actinobacteria	MU	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase,TIG
XH1_k127_6935151_0	644282.Deba_3266	3.397e-46	175.0	28N2R@1|root,2ZB8J@2|Bacteria,1R9S3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
XH1_k127_6938674_2	1316936.K678_14332	0.0005997	43.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,2JQMD@204441|Rhodospirillales	204441|Rhodospirillales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
XH1_k127_6938674_0	1125863.JAFN01000001_gene1723	9.205e-136	446.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the EPSP synthase family. MurA subfamily	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
XH1_k127_6938674_1	1125863.JAFN01000001_gene3091	2.241e-116	406.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
XH1_k127_6963112_2	583355.Caka_1501	5.943e-19	91.0	COG4719@1|root,COG4719@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
XH1_k127_6963112_0	751945.Theos_0849	9.564e-123	431.0	COG1470@1|root,COG4719@1|root,COG1470@2|Bacteria,COG4719@2|Bacteria,1WJNZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
XH1_k127_6963112_1	404380.Gbem_2718	1.154e-117	430.0	COG1361@1|root,COG2885@1|root,COG4719@1|root,COG1361@2|Bacteria,COG2885@2|Bacteria,COG4719@2|Bacteria,1QW22@1224|Proteobacteria	1224|Proteobacteria	M	Ompa motb domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA,SdrD_B
XH1_k127_6963112_3	1198452.Jab_1c06450	7.593e-10	74.0	COG4412@1|root,COG4733@1|root,COG4412@2|Bacteria,COG4733@2|Bacteria,1R2UN@1224|Proteobacteria,2WIDD@28216|Betaproteobacteria,4796E@75682|Oxalobacteraceae	2|Bacteria	S	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Peptidase_M6,Trypsin_2,fn3
XH1_k127_6970271_3	743720.Psefu_4192	5.634e-14	81.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1YXWE@136845|Pseudomonas putida group	1236|Gammaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
XH1_k127_6970271_2	94624.Bpet3617	1.615e-43	164.0	COG1917@1|root,COG1917@2|Bacteria,1RGXQ@1224|Proteobacteria,2VSZH@28216|Betaproteobacteria,3T4FT@506|Alcaligenaceae	28216|Betaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_6970271_1	404380.Gbem_1877	7.36e-117	409.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
XH1_k127_6970271_0	665571.STHERM_c02830	6.761e-207	655.0	COG0174@1|root,COG0174@2|Bacteria,2J6JS@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
XH1_k127_6980192_1	338963.Pcar_2611	1.695e-13	73.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,43VZ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	SelR domain	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
XH1_k127_6980192_0	661478.OP10G_0730	1.503e-36	154.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asp_protease_2,PDZ,PDZ_2,Peptidase_M28,Peptidase_S55
XH1_k127_7005835_3	401526.TcarDRAFT_0347	2.468e-08	57.0	COG0859@1|root,COG0859@2|Bacteria,1UZZI@1239|Firmicutes,4H2VC@909932|Negativicutes	909932|Negativicutes	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
XH1_k127_7005835_2	479434.Sthe_0045	3.931e-34	147.0	COG0859@1|root,COG0859@2|Bacteria,2GA3U@200795|Chloroflexi,27Z33@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
XH1_k127_7005835_0	335543.Sfum_0374	4.235e-47	179.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria,2MRJB@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH1_k127_7005835_1	479434.Sthe_0849	1.025e-42	176.0	COG0438@1|root,COG0438@2|Bacteria,2G8W3@200795|Chloroflexi,27Y3X@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
XH1_k127_7019271_0	1266914.ATUK01000002_gene539	1.465e-22	110.0	COG2199@1|root,COG2202@1|root,COG3290@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T4M3@1236|Gammaproteobacteria,1WY59@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,PAS_9
XH1_k127_7047213_9	1298920.KI911353_gene1203	2.741e-05	48.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,21YYY@1506553|Lachnoclostridium	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
XH1_k127_7047213_1	370438.PTH_0293	2.727e-129	436.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,26070@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
XH1_k127_7047213_6	177437.HRM2_23290	1.398e-45	172.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria,2MJZP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
XH1_k127_7047213_7	1131269.AQVV01000013_gene1773	5.125e-35	143.0	COG1211@1|root,COG1211@2|Bacteria	2|Bacteria	I	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
XH1_k127_7047213_5	1379698.RBG1_1C00001G0556	1.076e-48	188.0	COG1463@1|root,COG1463@2|Bacteria,2NPXB@2323|unclassified Bacteria	2|Bacteria	Q	MlaD protein	ttg2C	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
XH1_k127_7047213_2	1379698.RBG1_1C00001G0979	2.451e-91	308.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
XH1_k127_7047213_3	1379698.RBG1_1C00001G0978	5.235e-75	259.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
XH1_k127_7047213_0	671143.DAMO_0515	7.364e-150	487.0	COG0305@1|root,COG0305@2|Bacteria,2NNKG@2323|unclassified Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
XH1_k127_7047213_4	517418.Ctha_1942	3.866e-60	223.0	COG1573@1|root,COG1573@2|Bacteria,1FDUS@1090|Chlorobi	1090|Chlorobi	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
XH1_k127_7047213_8	661087.HMPREF1008_01554	2.957e-27	117.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4CUS0@84998|Coriobacteriia	84998|Coriobacteriia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
XH1_k127_7094452_0	1304284.L21TH_0179	5.454e-239	751.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,36HQZ@31979|Clostridiaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh,Pro_dh
XH1_k127_7094452_1	945713.IALB_2155	1.663e-147	482.0	COG2195@1|root,COG2195@2|Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepD	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	iPC815.YPO3230,iSBO_1134.SBO_0243	M20_dimer,Peptidase_M20
XH1_k127_7094452_4	1121468.AUBR01000020_gene2847	3.842e-44	165.0	COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia,42GHI@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
XH1_k127_7094452_3	485913.Krac_6669	7.425e-56	203.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
XH1_k127_7094452_5	1382306.JNIM01000001_gene1046	3.079e-35	155.0	COG4585@1|root,COG4585@2|Bacteria,2G6F0@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
XH1_k127_7094452_2	1382306.JNIM01000001_gene2893	1.117e-94	322.0	COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing protein	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
XH1_k127_7094452_6	479434.Sthe_2092	2.324e-23	104.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.1.11.5,3.1.12.1,3.6.4.12	ko:K01144,ko:K07464,ko:K16898	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
XH1_k127_7101952_12	1218173.BALCAV_0207900	7.981e-18	87.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
XH1_k127_7101952_0	1499967.BAYZ01000026_gene1569	1.259e-266	835.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
XH1_k127_7101952_3	1379698.RBG1_1C00001G0474	2.634e-96	331.0	COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria	2|Bacteria	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
XH1_k127_7101952_5	760568.Desku_1352	2.432e-73	263.0	COG1035@1|root,COG1145@1|root,COG1035@2|Bacteria,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	etfA	-	1.12.98.1,1.18.1.2,1.19.1.1	ko:K00441,ko:K00528,ko:K03522,ko:K03616	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025,R10159	RC02628	ko00000,ko00001,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4,Fer4_6,Fer4_7,Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
XH1_k127_7101952_14	309801.trd_1069	1.961e-16	90.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi,27XQ2@189775|Thermomicrobia	189775|Thermomicrobia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
XH1_k127_7101952_10	1122164.JHWF01000005_gene168	3.167e-33	137.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,1RPPT@1236|Gammaproteobacteria,1JE38@118969|Legionellales	118969|Legionellales	S	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.28	ko:K00638	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Hexapep
XH1_k127_7101952_13	326427.Cagg_0163	1.69e-17	94.0	COG0392@1|root,COG0392@2|Bacteria,2GADT@200795|Chloroflexi,375NR@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
XH1_k127_7101952_7	1128421.JAGA01000003_gene2950	1.733e-64	232.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH1_k127_7101952_16	1347369.CCAD010000066_gene3618	5.854e-08	55.0	2BPXI@1|root,32IR8@2|Bacteria,1UAVI@1239|Firmicutes,4IM8D@91061|Bacilli,1ZJGE@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7101952_15	1211814.CAPG01000082_gene3799	2.491e-13	70.0	2BF4Y@1|root,328X8@2|Bacteria,1UB8H@1239|Firmicutes,4IMM8@91061|Bacilli,1ZKEI@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7101952_2	517418.Ctha_1672	4.156e-128	426.0	COG0297@1|root,COG0297@2|Bacteria,1FDT0@1090|Chlorobi	1090|Chlorobi	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
XH1_k127_7101952_1	204669.Acid345_0343	7.098e-138	446.0	COG1085@1|root,COG1085@2|Bacteria,3Y41K@57723|Acidobacteria,2JMKJ@204432|Acidobacteriia	204432|Acidobacteriia	C	Domain of unknown function (DUF4921)	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C
XH1_k127_7101952_17	431947.PGN_0666	0.0006945	49.0	2E2TU@1|root,32XVZ@2|Bacteria,4NVA0@976|Bacteroidetes,2FUX1@200643|Bacteroidia,22YNI@171551|Porphyromonadaceae	976|Bacteroidetes	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
XH1_k127_7101952_4	1121456.ATVA01000012_gene2804	2.547e-75	271.0	COG0438@1|root,COG0438@2|Bacteria,1MUYN@1224|Proteobacteria,43F2S@68525|delta/epsilon subdivisions,2X35V@28221|Deltaproteobacteria,2ME5E@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
XH1_k127_7101952_6	1121456.ATVA01000012_gene2805	2.014e-68	246.0	COG0438@1|root,COG0535@1|root,COG0438@2|Bacteria,COG0535@2|Bacteria,1NB81@1224|Proteobacteria,42WA6@68525|delta/epsilon subdivisions,2WRYV@28221|Deltaproteobacteria,2MD0F@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,SPASM
XH1_k127_7101952_9	1380356.JNIK01000004_gene179	8.088e-49	197.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,4EW89@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
XH1_k127_7101952_8	1122182.KB903814_gene3226	1.028e-58	216.0	COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria,4DF0N@85008|Micromonosporales	201174|Actinobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
XH1_k127_7101952_11	525904.Tter_2814	7.261e-33	131.0	COG0673@1|root,COG0673@2|Bacteria,2NP38@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
XH1_k127_7113107_0	1379698.RBG1_1C00001G0340	3.754e-120	407.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
XH1_k127_7153034_0	518766.Rmar_0508	1.322e-117	403.0	COG2203@1|root,COG2204@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FJ5I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	Sigma54_activat
XH1_k127_7153034_1	926569.ANT_03540	8.467e-69	236.0	COG1839@1|root,COG1839@2|Bacteria,2G6BH@200795|Chloroflexi	200795|Chloroflexi	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
XH1_k127_7153034_2	644282.Deba_2179	4.312e-67	241.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
XH1_k127_7174209_0	1047013.AQSP01000075_gene1424	9.154e-253	793.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
XH1_k127_7194028_2	1499967.BAYZ01000174_gene5832	1.168e-11	76.0	COG3437@1|root,COG4191@1|root,COG5000@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65,4.6.1.1	ko:K01768,ko:K02488,ko:K17763	ko00230,ko02020,ko02025,ko04112,ko04113,ko04213,map00230,map02020,map02025,map04112,map04113,map04213	M00511,M00695	R00089,R00434,R08057	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022,ko03021	-	-	-	GGDEF,HAMP,HATPase_c,HisKA,HisKA_3,PAS,PAS_4,PAS_9,Response_reg
XH1_k127_7194028_1	457570.Nther_2022	6.932e-95	344.0	COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia	2|Bacteria	E	Beta-eliminating lyase	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
XH1_k127_7194028_0	203119.Cthe_0686	8.113e-106	356.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
XH1_k127_7195816_4	247490.KSU1_C0449	6.788e-98	345.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
XH1_k127_7195816_13	880073.Calab_0041	4.431e-20	106.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
XH1_k127_7195816_9	521674.Plim_1455	7.308e-39	159.0	COG0461@1|root,COG0461@2|Bacteria,2IZA7@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
XH1_k127_7195816_3	326297.Sama_0299	3.401e-100	338.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,2QADA@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM peptidase T2 asparaginase 2	aga	-	3.5.1.1,3.5.1.26	ko:K01424,ko:K01444	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase_2
XH1_k127_7195816_7	639282.DEFDS_0685	1.545e-76	283.0	COG0479@1|root,COG0479@2|Bacteria,2GF2E@200930|Deferribacteres	200930|Deferribacteres	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
XH1_k127_7195816_0	747365.Thena_0192	3.747e-219	694.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,42FNP@68295|Thermoanaerobacterales	186801|Clostridia	C	fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
XH1_k127_7195816_14	760142.Hipma_0138	1.357e-17	90.0	COG2142@1|root,COG2142@2|Bacteria,1Q5Y0@1224|Proteobacteria,4321V@68525|delta/epsilon subdivisions,2WX4X@28221|Deltaproteobacteria,2M79B@213113|Desulfurellales	28221|Deltaproteobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
XH1_k127_7195816_12	644282.Deba_1091	6.899e-21	98.0	COG2009@1|root,COG2009@2|Bacteria,1MZMK@1224|Proteobacteria,433FS@68525|delta/epsilon subdivisions,2WX63@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
XH1_k127_7195816_16	880072.Desac_0616	1.806e-16	87.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_M78
XH1_k127_7195816_2	696369.KI912183_gene1413	9.503e-139	468.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,26111@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
XH1_k127_7195816_1	935836.JAEL01000006_gene2802	6.241e-200	649.0	COG1205@1|root,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli,1ZDM5@1386|Bacillus	91061|Bacilli	L	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
XH1_k127_7195816_10	304371.MCP_0816	1.651e-28	125.0	COG3359@1|root,arCOG03130@2157|Archaea,2Y6XZ@28890|Euryarchaeota,2NARC@224756|Methanomicrobia	224756|Methanomicrobia	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
XH1_k127_7195816_6	517418.Ctha_2237	5.03e-78	278.0	COG0739@1|root,COG0739@2|Bacteria,1FDNC@1090|Chlorobi	1090|Chlorobi	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
XH1_k127_7195816_8	944481.JAFP01000001_gene672	3.554e-48	178.0	COG0164@1|root,COG1636@1|root,COG0164@2|Bacteria,COG1636@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria,2M6Q9@213113|Desulfurellales	28221|Deltaproteobacteria	L	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF208,RNase_HII
XH1_k127_7195816_5	264732.Moth_1625	3.742e-95	321.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
XH1_k127_7195816_15	580327.Tthe_1159	5.504e-17	82.0	COG2768@1|root,COG2768@2|Bacteria,1VET2@1239|Firmicutes,24QUH@186801|Clostridia,42J82@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM 4Fe-4S	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
XH1_k127_7195816_17	589865.DaAHT2_2123	9.191e-05	54.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WPVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
XH1_k127_7261541_2	398525.KB900701_gene1912	4.456e-05	57.0	COG2244@1|root,COG2244@2|Bacteria,1R77R@1224|Proteobacteria,2U2PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
XH1_k127_7261541_1	545276.KB898732_gene2390	5.827e-14	84.0	COG5653@1|root,COG5653@2|Bacteria,1QUMR@1224|Proteobacteria,1RN5W@1236|Gammaproteobacteria,1WVWZ@135613|Chromatiales	135613|Chromatiales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
XH1_k127_7261541_0	562970.Btus_0880	1.956e-92	315.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,4HAER@91061|Bacilli	91061|Bacilli	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
XH1_k127_732480_0	1232410.KI421418_gene2370	3.474e-81	293.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,43S66@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Glycoprotease family	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
XH1_k127_732480_2	224324.aq_109	6.728e-46	170.0	COG0347@1|root,COG0347@2|Bacteria,2G43N@200783|Aquificae	200783|Aquificae	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
XH1_k127_732480_1	105422.BBPM01000029_gene3861	2.739e-69	254.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,2NEN3@228398|Streptacidiphilus	201174|Actinobacteria	OT	Glutamate-ammonia ligase adenylyltransferase	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
XH1_k127_7353482_1	1232410.KI421425_gene1521	9.122e-168	540.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,43SDT@69541|Desulfuromonadales	28221|Deltaproteobacteria	A	Domain of unknown function (DUF3552)	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
XH1_k127_7353482_6	1379698.RBG1_1C00001G1122	2.529e-18	88.0	COG3027@1|root,COG3027@2|Bacteria,2NQ5R@2323|unclassified Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
XH1_k127_7353482_2	269799.Gmet_1416	4.293e-154	523.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,43TCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
XH1_k127_7353482_3	273068.TTE1689	1.352e-119	395.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,42EPG@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
XH1_k127_7353482_5	572479.Hprae_0816	1.819e-42	159.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3WARJ@53433|Halanaerobiales	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
XH1_k127_7353482_7	1232410.KI421413_gene675	1.433e-13	79.0	COG0291@1|root,COG0291@2|Bacteria,1QDQ4@1224|Proteobacteria,42VSG@68525|delta/epsilon subdivisions,2WREY@28221|Deltaproteobacteria,43SRN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein L35	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
XH1_k127_7353482_4	867903.ThesuDRAFT_01704	3.619e-51	189.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3WCI3@538999|Clostridiales incertae sedis	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
XH1_k127_7353482_0	1499967.BAYZ01000003_gene5878	7.758e-221	698.0	COG0441@1|root,COG0441@2|Bacteria,2NNMT@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
XH1_k127_7373214_4	1278073.MYSTI_06417	0.0001673	53.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_7373214_0	1499967.BAYZ01000171_gene5550	2.061e-26	115.0	COG1633@1|root,COG1633@2|Bacteria,2NS04@2323|unclassified Bacteria	2|Bacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_7373214_1	273068.TTE2154	4.975e-21	95.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,42H59@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
XH1_k127_7373214_2	931626.Awo_c27990	8.182e-13	74.0	COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1V7DF@1239|Firmicutes,24G44@186801|Clostridia,25VSF@186806|Eubacteriaceae	186801|Clostridia	C	Flavin reductase like domain	hrb	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubredoxin
XH1_k127_7373214_3	765912.Thimo_0258	2.09e-05	51.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_7412619_8	269797.Mbar_A2132	2.367e-47	175.0	COG0454@1|root,arCOG00826@2157|Archaea,2XYKC@28890|Euryarchaeota,2NA1W@224756|Methanomicrobia	224756|Methanomicrobia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
XH1_k127_7412619_10	305700.B447_02773	1.432e-24	120.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VHM2@28216|Betaproteobacteria,2KVFD@206389|Rhodocyclales	206389|Rhodocyclales	M	PEP-CTERM exosortase 1-associated glycosyltransferase, Daro_2409 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
XH1_k127_7412619_2	1047013.AQSP01000130_gene1847	1.613e-127	432.0	COG4232@1|root,COG4232@2|Bacteria,2NPKJ@2323|unclassified Bacteria	2|Bacteria	CO	Protein of unknown function, DUF255	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
XH1_k127_7412619_12	404589.Anae109_2327	6.322e-08	66.0	COG3506@1|root,COG5276@1|root,COG3506@2|Bacteria,COG5276@2|Bacteria,1Q8G3@1224|Proteobacteria,438JI@68525|delta/epsilon subdivisions,2X3U7@28221|Deltaproteobacteria,2YX4C@29|Myxococcales	28221|Deltaproteobacteria	U	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,TIG
XH1_k127_7412619_9	370438.PTH_1315	8.433e-36	145.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JDV@186801|Clostridia,261XP@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the phosphoglycerate mutase family	pspA	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
XH1_k127_7412619_7	1379698.RBG1_1C00001G0457	1.171e-63	226.0	COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria	2|Bacteria	S	(Rhomboid) family	GlpG	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	Rhomboid
XH1_k127_7412619_4	1128421.JAGA01000002_gene175	1.569e-86	303.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	adhA7	-	1.1.1.1,1.1.1.264,1.1.1.303,1.1.1.4	ko:K00001,ko:K00004,ko:K00098	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R02855,R02946,R04805,R04880,R05233,R05234,R05684,R06917,R06927,R07105,R08281,R08306,R08310,R10504	RC00050,RC00087,RC00088,RC00089,RC00099,RC00116,RC00205,RC00525,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
XH1_k127_7412619_13	762982.HMPREF9442_02462	1.325e-06	59.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	-	-	1.1.1.367	ko:K19068	-	-	-	-	ko00000,ko01000	-	-	-	FdtA
XH1_k127_7412619_5	639282.DEFDS_0585	1.8e-82	282.0	COG1611@1|root,COG1611@2|Bacteria,2GEPC@200930|Deferribacteres	200930|Deferribacteres	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
XH1_k127_7412619_6	1379698.RBG1_1C00001G1133	3.864e-67	239.0	COG1575@1|root,COG1575@2|Bacteria,2NPNN@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
XH1_k127_7412619_3	358396.C445_18396	1.536e-91	323.0	COG2057@1|root,arCOG05316@2157|Archaea,2XW2C@28890|Euryarchaeota,23U50@183963|Halobacteria	183963|Halobacteria	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
XH1_k127_7412619_1	224325.AF_1199	5.857e-136	449.0	COG1788@1|root,arCOG01987@2157|Archaea,2XVRA@28890|Euryarchaeota,246WP@183980|Archaeoglobi	183980|Archaeoglobi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
XH1_k127_7412619_0	1125863.JAFN01000001_gene170	1.056e-176	561.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_7412619_11	714943.Mucpa_3747	4.897e-13	76.0	COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,1IZ2D@117747|Sphingobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
XH1_k127_7545533_6	237368.SCABRO_01468	0.0009281	50.0	COG0769@1|root,COG0769@2|Bacteria,2IWUT@203682|Planctomycetes	203682|Planctomycetes	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
XH1_k127_7545533_0	1123288.SOV_1c09940	7.685e-87	314.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H1WR@909932|Negativicutes	909932|Negativicutes	M	PFAM penicillin-binding protein transpeptidase, Penicillin-binding protein dimerization domain-containing protein, PASTA domain containing protein	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
XH1_k127_7545533_1	498761.HM1_2051	8.917e-73	260.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
XH1_k127_7545533_4	1828.JOKB01000025_gene1903	7.889e-13	75.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4G0KG@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
XH1_k127_7545533_5	479435.Kfla_4924	2.683e-09	70.0	COG2227@1|root,COG2227@2|Bacteria,2GMMX@201174|Actinobacteria,4DUFI@85009|Propionibacteriales	201174|Actinobacteria	H	Methyltransferase domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
XH1_k127_7545533_3	926569.ANT_11560	1.44e-18	100.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH1_k127_7545533_2	1089548.KI783301_gene2313	3.424e-51	200.0	COG0438@1|root,COG0438@2|Bacteria,1UTQH@1239|Firmicutes,4HBYI@91061|Bacilli,3WFUU@539002|Bacillales incertae sedis	91061|Bacilli	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
XH1_k127_7593799_3	562970.Btus_0771	5.193e-87	300.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,2785Z@186823|Alicyclobacillaceae	91061|Bacilli	T	AAA domain	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
XH1_k127_7593799_8	316274.Haur_0233	1.631e-11	73.0	COG1652@1|root,COG1652@2|Bacteria,2G9GB@200795|Chloroflexi	200795|Chloroflexi	S	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM
XH1_k127_7593799_0	370438.PTH_1049	1.618e-185	598.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,260AT@186807|Peptococcaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
XH1_k127_7593799_1	706434.HMPREF9429_01552	1.74e-121	408.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4H20Q@909932|Negativicutes	909932|Negativicutes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
XH1_k127_7593799_7	459349.CLOAM1235	7.061e-12	72.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
XH1_k127_7593799_6	667014.Thein_0075	1.252e-22	109.0	COG4856@1|root,COG4856@2|Bacteria,2GGRH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
XH1_k127_7593799_4	1121935.AQXX01000114_gene3272	4.398e-51	196.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1XHQX@135619|Oceanospirillales	135619|Oceanospirillales	M	N-acetylmuramoyl-L-alanine amidase	amiB	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
XH1_k127_7593799_5	644282.Deba_2866	6.467e-43	169.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
XH1_k127_7593799_2	1379698.RBG1_1C00001G0598	2.05e-99	333.0	COG0568@1|root,COG0568@2|Bacteria,2NNY9@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
XH1_k127_7597347_0	1191523.MROS_1854	2.054e-29	121.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
XH1_k127_7597347_1	1499967.BAYZ01000088_gene5144	2.177e-13	80.0	COG2172@1|root,COG2172@2|Bacteria,2NQ1S@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma regulatory factor (Ser Thr protein kinase)	rsbW	-	2.7.11.1	ko:K04757,ko:K06379,ko:K08282	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
XH1_k127_7628456_13	1499967.BAYZ01000180_gene4404	1.082e-20	105.0	COG0457@1|root,COG0457@2|Bacteria	1499967.BAYZ01000180_gene4404|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7628456_11	1379698.RBG1_1C00001G1162	8.807e-36	156.0	COG0726@1|root,COG0726@2|Bacteria,2NPY1@2323|unclassified Bacteria	2|Bacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Polysacc_deac_1
XH1_k127_7628456_10	1191523.MROS_0291	1.372e-43	163.0	COG0756@1|root,COG0756@2|Bacteria	2|Bacteria	F	dUTP diphosphatase activity	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23,4.1.1.36,6.3.2.5	ko:K01520,ko:K13038	ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100	M00053,M00120	R02100,R03269,R04231,R11896	RC00002,RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
XH1_k127_7628456_4	635013.TherJR_1392	1.354e-72	263.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,260B8@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the peptidase M16 family	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
XH1_k127_7628456_0	1131269.AQVV01000001_gene1389	4.749e-223	712.0	COG1185@1|root,COG1185@2|Bacteria	2|Bacteria	J	polyribonucleotide nucleotidyltransferase activity	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
XH1_k127_7628456_12	246194.CHY_1760	2.751e-29	118.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,42GTG@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
XH1_k127_7628456_7	573370.DMR_06190	7.562e-61	221.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2M8RD@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
XH1_k127_7628456_9	1266908.AQPB01000045_gene890	5.983e-51	195.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1WVXW@135613|Chromatiales	135613|Chromatiales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
XH1_k127_7628456_8	498761.HM1_2316	6.451e-54	203.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia	186801|Clostridia	J	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
XH1_k127_7628456_15	373903.Hore_07850	7.392e-18	88.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3WAT9@53433|Halanaerobiales	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
XH1_k127_7628456_16	880073.Calab_3553	9.189e-16	80.0	COG1550@1|root,COG1550@2|Bacteria,2NPYX@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF503)	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
XH1_k127_7628456_1	945713.IALB_0639	6.148e-209	671.0	COG0532@1|root,COG0532@2|Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
XH1_k127_7628456_3	1379698.RBG1_1C00001G1152	1.046e-109	375.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
XH1_k127_7628456_14	1123261.AXDW01000001_gene1108	2.212e-20	102.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1X5YX@135614|Xanthomonadales	135614|Xanthomonadales	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
XH1_k127_7628456_5	1379698.RBG1_1C00001G0436	1.371e-69	252.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
XH1_k127_7628456_2	459349.CLOAM1149	1.296e-112	414.0	COG1747@1|root,COG3064@1|root,COG1747@2|Bacteria,COG3064@2|Bacteria,2NP33@2323|unclassified Bacteria	2|Bacteria	M	methyltransferase	greA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	GreA_GreB,GreA_GreB_N,SprA_N
XH1_k127_7628456_6	1379698.RBG1_1C00001G1858	2.404e-63	228.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
XH1_k127_77668_1	330214.NIDE1358	1.513e-78	271.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,3J0EB@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
XH1_k127_77668_2	1121904.ARBP01000001_gene5465	3.542e-62	235.0	COG3595@1|root,COG3595@2|Bacteria,4NJCC@976|Bacteroidetes,47MIA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
XH1_k127_77668_5	404380.Gbem_1112	9.582e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
XH1_k127_77668_3	945713.IALB_2700	3.764e-41	159.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	lrp_1	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141	-	ko:K03719,ko:K05800	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
XH1_k127_77668_0	926561.KB900618_gene161	1.472e-117	390.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WCB2@53433|Halanaerobiales	186801|Clostridia	E	Cys Met metabolism	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
XH1_k127_77668_4	420246.GTNG_2268	8.969e-07	51.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,1WE9G@129337|Geobacillus	91061|Bacilli	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
XH1_k127_7790727_0	880073.Calab_2402	1.387e-34	154.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7790727_1	439235.Dalk_4601	0.0001621	46.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2MKNW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
XH1_k127_7799637_9	330214.NIDE3038	3.666e-71	254.0	COG0673@1|root,COG0673@2|Bacteria,3J0M7@40117|Nitrospirae	40117|Nitrospirae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
XH1_k127_7799637_6	1009370.ALO_19302	6.174e-83	284.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes	909932|Negativicutes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep,Hexapep_2
XH1_k127_7799637_0	1379698.RBG1_1C00001G1649	6.628e-132	450.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2NNYX@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022	-	-	-	FabA,LpxC
XH1_k127_7799637_4	1379698.RBG1_1C00001G1848	1.396e-104	351.0	COG1044@1|root,COG1044@2|Bacteria,2NNSF@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	ic_1306.c0216	Hexapep,Hexapep_2,LpxD
XH1_k127_7799637_11	1379698.RBG1_1C00001G1847	8.375e-34	136.0	COG2825@1|root,COG2825@2|Bacteria,2NQ6C@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
XH1_k127_7799637_5	1121413.JMKT01000008_gene1022	9.485e-93	333.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2M8BJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
XH1_k127_7799637_10	1411123.JQNH01000001_gene3191	2.771e-63	222.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,2TUBI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	NAD(P)H-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
XH1_k127_7799637_14	1033810.HLPCO_002951	6.006e-12	77.0	COG1978@1|root,COG1978@2|Bacteria,2NRV0@2323|unclassified Bacteria	2|Bacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1,1.21.4.2	ko:K10672,ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
XH1_k127_7799637_13	1122917.KB899673_gene696	2.318e-26	126.0	COG0189@1|root,COG0189@2|Bacteria,1TWCJ@1239|Firmicutes,4HB5J@91061|Bacilli,27098@186822|Paenibacillaceae	91061|Bacilli	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	lysX_2	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
XH1_k127_7799637_8	498848.TaqDRAFT_4490	7.842e-73	270.0	COG0641@1|root,COG0641@2|Bacteria,1WJKB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	4Fe-4S single cluster domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
XH1_k127_7799637_15	180281.CPCC7001_1464	2.054e-07	63.0	COG0845@1|root,COG0845@2|Bacteria,1G29T@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
XH1_k127_7799637_3	1123489.AUAN01000008_gene154	8.003e-106	377.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
XH1_k127_7799637_7	945713.IALB_2314	8.77e-82	295.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
XH1_k127_7799637_2	1192034.CAP_0196	2.316e-106	357.0	COG3503@1|root,COG3503@2|Bacteria,1QQ9D@1224|Proteobacteria,431ME@68525|delta/epsilon subdivisions,2WWTB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
XH1_k127_7799637_12	56780.SYN_01961	3.443e-33	138.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25,LysM,PG_binding_1,Peptidase_C14
XH1_k127_7799637_1	247490.KSU1_C0449	2.44e-114	381.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
XH1_k127_7834969_3	391625.PPSIR1_04013	8.738e-06	57.0	COG0308@1|root,COG0308@2|Bacteria,1NJK3@1224|Proteobacteria,42Y4Q@68525|delta/epsilon subdivisions,2WTET@28221|Deltaproteobacteria,2YVW2@29|Myxococcales	28221|Deltaproteobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
XH1_k127_7834969_1	269799.Gmet_0873	2.504e-77	286.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
XH1_k127_7834969_0	401526.TcarDRAFT_0036	6.688e-125	413.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4H31K@909932|Negativicutes	909932|Negativicutes	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
XH1_k127_7834969_2	469606.FSCG_01468	4.154e-06	53.0	COG0457@1|root,COG0457@2|Bacteria,378JR@32066|Fusobacteria	32066|Fusobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_12,TPR_2,TPR_8
XH1_k127_7863440_6	290397.Adeh_0920	2.065e-10	65.0	2EPJ1@1|root,33H5P@2|Bacteria,1PP7Z@1224|Proteobacteria,432VT@68525|delta/epsilon subdivisions,2WYJ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7863440_7	1121448.DGI_2312	5.035e-09	63.0	2BJC2@1|root,32DN6@2|Bacteria,1PZWS@1224|Proteobacteria,4367R@68525|delta/epsilon subdivisions,2X0S2@28221|Deltaproteobacteria,2MD8K@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7863440_2	1125863.JAFN01000001_gene2422	5.159e-76	269.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,42NVB@68525|delta/epsilon subdivisions,2WK6R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
XH1_k127_7863440_5	1121918.ARWE01000001_gene20	3.027e-40	172.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,42SH5@68525|delta/epsilon subdivisions,2WP2N@28221|Deltaproteobacteria,43SM7@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	FMN_bind	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
XH1_k127_7863440_1	1232410.KI421424_gene1777	2.26e-105	353.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,42QE5@68525|delta/epsilon subdivisions,2WM8R@28221|Deltaproteobacteria,43S58@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NQR2, RnfD, RnfE family	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
XH1_k127_7863440_0	401526.TcarDRAFT_1672	1.571e-136	460.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,4H31M@909932|Negativicutes	909932|Negativicutes	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_4,Fer4_8,RnfC_N,SLBB
XH1_k127_7863440_4	1121289.JHVL01000002_gene2427	1.056e-68	243.0	COG1142@1|root,COG2878@1|root,COG1142@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,36FC4@31979|Clostridiaceae	186801|Clostridia	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
XH1_k127_7863440_3	1121918.ARWE01000001_gene24	6.143e-73	252.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,42MCM@68525|delta/epsilon subdivisions,2WKRE@28221|Deltaproteobacteria,43SD5@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Rnf-Nqr subunit, membrane protein	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
XH1_k127_786570_1	1121468.AUBR01000045_gene1802	2.032e-74	258.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
XH1_k127_786570_0	1341151.ASZU01000012_gene1687	5.462e-258	805.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,27BE2@186824|Thermoactinomycetaceae	91061|Bacilli	E	Urocanase C-terminal domain	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
XH1_k127_786570_2	1123239.KB898624_gene1876	4.481e-50	190.0	COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli	91061|Bacilli	L	helicase involved in DNA repair and perhaps also replication	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
XH1_k127_7869927_20	1274.HX89_06195	5.935e-05	52.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,1ZWJC@145357|Dermacoccaceae	201174|Actinobacteria	KLT	Protein kinase domain	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
XH1_k127_7869927_8	518766.Rmar_2549	2.386e-82	284.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1FJ62@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
XH1_k127_7869927_11	65093.PCC7418_2849	4.95e-38	149.0	COG0242@1|root,COG0242@2|Bacteria,1G1FB@1117|Cyanobacteria	1117|Cyanobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
XH1_k127_7869927_18	1125863.JAFN01000001_gene1343	1.07e-19	92.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
XH1_k127_7869927_3	880073.Calab_3729	7.685e-130	425.0	COG0343@1|root,COG0343@2|Bacteria,2NNQS@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
XH1_k127_7869927_6	868864.Dester_1458	8.347e-90	322.0	COG0809@1|root,COG0809@2|Bacteria,2G3KG@200783|Aquificae	200783|Aquificae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
XH1_k127_7869927_4	653733.Selin_1133	5.866e-124	408.0	COG2255@1|root,COG2255@2|Bacteria	2|Bacteria	L	four-way junction helicase activity	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
XH1_k127_7869927_13	1280698.AUJS01000001_gene3205	3.179e-36	147.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,27VGR@189330|Dorea	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
XH1_k127_7869927_10	1187848.AJYQ01000066_gene3590	3.893e-40	161.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1XT73@135623|Vibrionales	135623|Vibrionales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
XH1_k127_7869927_7	1499967.BAYZ01000068_gene1977	7.479e-86	291.0	COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
XH1_k127_7869927_0	1379698.RBG1_1C00001G0830	7.38e-229	728.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
XH1_k127_7869927_21	1291050.JAGE01000001_gene3033	7.259e-05	53.0	2EC4I@1|root,3363E@2|Bacteria,1VJH4@1239|Firmicutes,25E22@186801|Clostridia	186801|Clostridia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
XH1_k127_7869927_17	1125863.JAFN01000001_gene865	5.658e-22	108.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
XH1_k127_7869927_12	1254432.SCE1572_28200	1.414e-36	155.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T55@68525|delta/epsilon subdivisions,2WPW2@28221|Deltaproteobacteria,2YY5H@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
XH1_k127_7869927_9	218284.CCDN010000008_gene4081	1.892e-75	269.0	COG1215@1|root,COG1215@2|Bacteria,1TPY9@1239|Firmicutes,4HF9W@91061|Bacilli,1ZGWH@1386|Bacillus	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH1_k127_7869927_16	215803.DB30_1517	1.134e-24	121.0	COG2204@1|root,COG3292@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria,2YUEQ@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Reg_prop,Response_reg,Y_Y_Y
XH1_k127_7869927_19	1300345.LF41_1026	8.805e-12	78.0	COG3975@1|root,COG3975@2|Bacteria	2|Bacteria	-	-	spoIVB	-	3.4.21.116,3.4.24.3	ko:K01387,ko:K06399	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	Peptidase_M61,Peptidase_M9,Peptidase_M9_N
XH1_k127_7869927_14	401053.AciPR4_2609	3.885e-28	129.0	COG3206@1|root,COG3206@2|Bacteria,3Y2PJ@57723|Acidobacteria,2JHP9@204432|Acidobacteriia	204432|Acidobacteriia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
XH1_k127_7869927_15	349124.Hhal_2363	9.474e-27	123.0	COG0438@1|root,COG0438@2|Bacteria,1PDW1@1224|Proteobacteria,1RZIK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Capsular polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
XH1_k127_7869927_2	335543.Sfum_2577	1.602e-152	497.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2MR42@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
XH1_k127_7869927_1	1121468.AUBR01000001_gene579	2.296e-191	611.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,42FA0@68295|Thermoanaerobacterales	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
XH1_k127_7869927_5	518766.Rmar_2008	6.437e-110	361.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1FJ1P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
XH1_k127_7982173_9	1158294.JOMI01000001_gene1529	6.931e-18	96.0	2CK1R@1|root,32V4M@2|Bacteria,4NTYZ@976|Bacteroidetes,2FU5M@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_7982173_4	913865.DOT_3845	6.013e-99	336.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,260ZP@186807|Peptococcaceae	186801|Clostridia	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
XH1_k127_7982173_6	1499967.BAYZ01000123_gene2533	3.26e-46	185.0	COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
XH1_k127_7982173_3	518766.Rmar_0833	5.999e-113	381.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1FIMK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
XH1_k127_7982173_8	589924.Ferp_2552	1.014e-32	132.0	COG1545@1|root,arCOG01287@2157|Archaea,2Y3J3@28890|Euryarchaeota,24718@183980|Archaeoglobi	183980|Archaeoglobi	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
XH1_k127_7982173_5	387631.Asulf_00172	3.385e-53	194.0	COG1545@1|root,arCOG01287@2157|Archaea,2Y2YT@28890|Euryarchaeota,246S2@183980|Archaeoglobi	183980|Archaeoglobi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
XH1_k127_7982173_0	1379698.RBG1_1C00001G1464	4.143e-188	595.0	COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	ltp4	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C
XH1_k127_7982173_1	589924.Ferp_2555	1.152e-113	378.0	COG0183@1|root,arCOG01279@2157|Archaea,2Y2G9@28890|Euryarchaeota,246XN@183980|Archaeoglobi	183980|Archaeoglobi	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C
XH1_k127_7982173_11	1267535.KB906767_gene3905	1.203e-09	66.0	COG3682@1|root,COG3682@2|Bacteria,3Y8BB@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
XH1_k127_7982173_10	1123242.JH636435_gene2179	3.303e-11	76.0	COG4219@1|root,COG4219@2|Bacteria,2J096@203682|Planctomycetes	2|Bacteria	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_M56,Peptidase_S11,TonB_C
XH1_k127_7982173_12	563192.HMPREF0179_01559	0.0009133	46.0	2D16E@1|root,32TA0@2|Bacteria,1MZ7W@1224|Proteobacteria,43BJ0@68525|delta/epsilon subdivisions,2WSQT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Motility quorum-sensing regulator, toxin of MqsA	-	-	-	ko:K13651	-	-	-	-	ko00000,ko02048	-	-	-	MqsR_toxin
XH1_k127_7982173_2	1121468.AUBR01000045_gene1791	2.374e-113	390.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,42FGT@68295|Thermoanaerobacterales	186801|Clostridia	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
XH1_k127_7982173_7	518766.Rmar_2032	6.015e-38	164.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1FJ3U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
XH1_k127_8019562_2	985255.APHJ01000025_gene1124	4.43e-16	92.0	COG0457@1|root,COG0596@1|root,COG0457@2|Bacteria,COG0596@2|Bacteria,4NPQR@976|Bacteroidetes,1I2GI@117743|Flavobacteriia	976|Bacteroidetes	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
XH1_k127_8019562_0	861299.J421_1461	2.906e-45	184.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
XH1_k127_8019562_1	886293.Sinac_6279	1.151e-23	104.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
XH1_k127_8113818_0	880073.Calab_1134	2.693e-218	706.0	COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
XH1_k127_8113818_1	1118054.CAGW01000007_gene3842	2.408e-55	208.0	COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HB9F@91061|Bacilli	91061|Bacilli	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
XH1_k127_8148183_3	1434325.AZQN01000002_gene1056	3.251e-12	68.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,47JFM@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
XH1_k127_8148183_0	290317.Cpha266_0617	2.175e-44	172.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1FDBJ@1090|Chlorobi	1090|Chlorobi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg,dCache_3
XH1_k127_8148183_1	1121930.AQXG01000001_gene1216	1.69e-25	121.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Beta_helix,F5_F8_type_C
XH1_k127_8148183_2	247490.KSU1_C0449	3.375e-22	110.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
XH1_k127_816496_1	1267535.KB906767_gene3339	3.019e-53	198.0	COG3279@1|root,COG3279@2|Bacteria,3Y3HR@57723|Acidobacteria,2JIXA@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
XH1_k127_816496_0	204669.Acid345_4032	6.849e-95	331.0	COG2972@1|root,COG2972@2|Bacteria,3Y3NH@57723|Acidobacteria,2JHT4@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,His_kinase
XH1_k127_816496_2	1499967.BAYZ01000185_gene4533	1.227e-32	134.0	2CA4A@1|root,32RQK@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
XH1_k127_816496_3	1499967.BAYZ01000185_gene4532	1.749e-09	66.0	COG2162@1|root,COG2162@2|Bacteria	2|Bacteria	Q	arylamine N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_2
XH1_k127_8222713_2	1499967.BAYZ01000054_gene4790	4.081e-56	217.0	COG5000@1|root,COG5000@2|Bacteria,2NQEP@2323|unclassified Bacteria	2|Bacteria	T	COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9,sCache_3_2
XH1_k127_8222713_1	1232410.KI421428_gene1054	6.715e-139	456.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_8222713_5	1121918.ARWE01000001_gene1280	2.453e-07	64.0	COG2980@1|root,COG2980@2|Bacteria,1NIUQ@1224|Proteobacteria,42XGJ@68525|delta/epsilon subdivisions,2WSS7@28221|Deltaproteobacteria,43V49@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
XH1_k127_8222713_4	1121904.ARBP01000009_gene4149	1.219e-20	104.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,47M1Q@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
XH1_k127_8222713_3	309807.SRU_2657	5.111e-27	113.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1FJEP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
XH1_k127_8222713_0	247490.KSU1_D0809	1.121e-301	950.0	COG0495@1|root,COG0495@2|Bacteria,2IX36@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
XH1_k127_8222713_6	411473.RUMCAL_02167	0.000172	49.0	COG4818@1|root,COG4818@2|Bacteria,1VG59@1239|Firmicutes,24VR1@186801|Clostridia,3WMMQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8231354_0	682795.AciX8_4290	7.857e-35	139.0	COG0657@1|root,COG0657@2|Bacteria,3Y6FP@57723|Acidobacteria,2JM6P@204432|Acidobacteriia	204432|Acidobacteriia	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8282826_3	330214.NIDE2556	7.417e-78	271.0	COG2877@1|root,COG2877@2|Bacteria,3J0AK@40117|Nitrospirae	40117|Nitrospirae	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
XH1_k127_8282826_0	697284.ERIC2_c39010	2.319e-223	717.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,26RTB@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
XH1_k127_8282826_5	574087.Acear_2185	1.005e-61	231.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,3WAKF@53433|Halanaerobiales	186801|Clostridia	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
XH1_k127_8282826_4	387092.NIS_0837	8.234e-67	248.0	COG1838@1|root,COG1838@2|Bacteria,1RCSV@1224|Proteobacteria,42NRW@68525|delta/epsilon subdivisions,2YN5M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Fumarate	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
XH1_k127_8282826_2	246194.CHY_1375	3.196e-109	363.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,42EX5@68295|Thermoanaerobacterales	186801|Clostridia	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
XH1_k127_8282826_6	909663.KI867151_gene3156	3.248e-47	183.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WNMC@28221|Deltaproteobacteria,2MQPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
XH1_k127_8282826_7	582515.KR51_00013650	1.47e-35	136.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
XH1_k127_8282826_9	1033802.SSPSH_003260	3.533e-23	102.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
XH1_k127_8282826_8	264731.PRU_0570	7.778e-26	111.0	COG3655@1|root,COG3655@2|Bacteria,4NUP7@976|Bacteroidetes,2FTVE@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
XH1_k127_8282826_11	366602.Caul_0169	0.0001184	53.0	2DZQF@1|root,32VG9@2|Bacteria,1MZ9P@1224|Proteobacteria,2UDR3@28211|Alphaproteobacteria,2KGZ4@204458|Caulobacterales	204458|Caulobacterales	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
XH1_k127_8282826_1	1379698.RBG1_1C00001G0983	3.735e-134	450.0	COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria	2|Bacteria	J	Ribonuclease E/G family	rng	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
XH1_k127_8282826_10	264732.Moth_0555	8.351e-20	100.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,42G8C@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
XH1_k127_8310476_3	517417.Cpar_0163	2.65e-89	324.0	COG4485@1|root,COG4485@2|Bacteria,1FFQB@1090|Chlorobi	1090|Chlorobi	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8310476_2	1379698.RBG1_1C00001G0996	9.507e-96	322.0	COG0463@1|root,COG0463@2|Bacteria,2NS3Y@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
XH1_k127_8310476_1	1499967.BAYZ01000063_gene6022	4.982e-105	366.0	COG1216@1|root,COG2148@1|root,COG1216@2|Bacteria,COG2148@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	ko:K03606,ko:K07011	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
XH1_k127_8310476_5	1408813.AYMG01000013_gene1313	0.0001639	56.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1IV0M@117747|Sphingobacteriia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
XH1_k127_8310476_4	1499967.BAYZ01000061_gene5977	5.556e-13	84.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_2,PAS_9,Reg_prop,Response_reg,Y_Y_Y
XH1_k127_8310476_0	768710.DesyoDRAFT_5080	8.314e-120	406.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,26076@186807|Peptococcaceae	186801|Clostridia	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_syn_2C,Polysacc_synt_2
XH1_k127_8314895_2	237368.SCABRO_02223	9.821e-15	74.0	COG0714@1|root,COG0714@2|Bacteria,2IX23@203682|Planctomycetes	203682|Planctomycetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
XH1_k127_8314895_0	237368.SCABRO_01880	2.803e-115	377.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
XH1_k127_8314895_1	237368.SCABRO_01881	3.518e-33	141.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8315590_2	177439.DP0498	5.811e-31	124.0	COG0011@1|root,COG0011@2|Bacteria,1PTFE@1224|Proteobacteria,43EYI@68525|delta/epsilon subdivisions,2WTF2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
XH1_k127_8315590_0	177439.DP0497	5.922e-135	443.0	COG0309@1|root,COG0309@2|Bacteria,1N04A@1224|Proteobacteria,437IA@68525|delta/epsilon subdivisions,2WYKF@28221|Deltaproteobacteria,2MP0D@213118|Desulfobacterales	28221|Deltaproteobacteria	O	AIR synthase related protein, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
XH1_k127_8315590_1	1304885.AUEY01000090_gene2886	1.944e-54	193.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42RB9@68525|delta/epsilon subdivisions,2WMPE@28221|Deltaproteobacteria,2MJPY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ferritin-like domain	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
XH1_k127_8324037_3	204669.Acid345_2392	6.81e-210	661.0	COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria,2JIPN@204432|Acidobacteriia	204432|Acidobacteriia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
XH1_k127_8324037_8	330214.NIDE2979	1.285e-101	350.0	COG0265@1|root,COG0265@2|Bacteria,3J0X9@40117|Nitrospirae	2|Bacteria	M	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	htrA	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
XH1_k127_8324037_16	33905.BTHE_2001	1.045e-20	98.0	COG1254@1|root,COG1254@2|Bacteria,2HZRI@201174|Actinobacteria,4D1EM@85004|Bifidobacteriales	201174|Actinobacteria	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
XH1_k127_8324037_14	1499967.BAYZ01000118_gene3289	2.597e-45	172.0	COG0288@1|root,COG0288@2|Bacteria,2NPWG@2323|unclassified Bacteria	2|Bacteria	P	Carbonic anhydrase	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
XH1_k127_8324037_0	56780.SYN_02218	0.0	1049.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
XH1_k127_8324037_9	1047013.AQSP01000119_gene1318	3.116e-66	233.0	COG4843@1|root,COG4843@2|Bacteria,2NPKB@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
XH1_k127_8324037_2	335543.Sfum_1361	5.201e-286	905.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,2MQ6G@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
XH1_k127_8324037_7	335543.Sfum_1360	5.983e-119	393.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,2MQ6W@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
XH1_k127_8324037_6	671143.DAMO_0892	3.585e-126	412.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	3.4.22.38	ko:K01371	ko04142,ko04210,ko04380,ko04620,ko05323,map04142,map04210,map04380,map04620,map05323	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_C1
XH1_k127_8324037_4	604354.TSIB_0718	1.021e-156	517.0	COG0477@1|root,arCOG00143@2157|Archaea,2Y8EH@28890|Euryarchaeota,245MX@183968|Thermococci	183968|Thermococci	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
XH1_k127_8324037_10	679935.Alfi_1844	1.371e-50	187.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,2FMUN@200643|Bacteroidia	976|Bacteroidetes	S	Flavin reductase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
XH1_k127_8324037_1	555079.Toce_2133	2.393e-296	926.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,42F6G@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
XH1_k127_8324037_13	477974.Daud_1589	2.862e-46	181.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,261GN@186807|Peptococcaceae	186801|Clostridia	T	PFAM Protein phosphatase 2C	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
XH1_k127_8324037_12	335543.Sfum_1584	4.769e-48	186.0	28I4Y@1|root,2Z88D@2|Bacteria,1R95V@1224|Proteobacteria,42RX3@68525|delta/epsilon subdivisions,2WMGE@28221|Deltaproteobacteria,2MQFS@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_8324037_11	1131269.AQVV01000016_gene1838	8.887e-50	201.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	pgp	-	-	-	-	-	-	-	-	-	-	-	HAD_2
XH1_k127_8324037_5	56780.SYN_01990	3.319e-152	495.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2MQ8K@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM MgsA AAA ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
XH1_k127_8324037_23	1410674.JNKU01000014_gene484	0.0006633	48.0	2DRDQ@1|root,33BBA@2|Bacteria,1VMFY@1239|Firmicutes,4I0ZJ@91061|Bacilli,3F84Z@33958|Lactobacillaceae	91061|Bacilli	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
XH1_k127_8324037_22	999549.KI421513_gene2584	0.0002154	53.0	COG0457@1|root,COG0457@2|Bacteria,1RFAH@1224|Proteobacteria,2U7KD@28211|Alphaproteobacteria,280KN@191028|Leisingera	28211|Alphaproteobacteria	S	Coatomer epsilon subunit	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_16,TPR_2,TPR_8
XH1_k127_8324037_19	290397.Adeh_2386	3.119e-11	71.0	COG0457@1|root,COG0457@2|Bacteria,1P4QM@1224|Proteobacteria,4334V@68525|delta/epsilon subdivisions,2WX62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
XH1_k127_8324037_18	945713.IALB_1926	1.448e-11	76.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
XH1_k127_8324037_15	1191523.MROS_0972	3.705e-29	137.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_S8
XH1_k127_8324037_21	386456.JQKN01000012_gene969	1.598e-06	62.0	COG1404@1|root,arCOG09729@1|root,arCOG00702@2157|Archaea,arCOG09729@2157|Archaea,2XUT1@28890|Euryarchaeota	28890|Euryarchaeota	O	COG1404 Subtilisin-like serine proteases	hly	GO:0005575,GO:0005576	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8,TAT_signal
XH1_k127_832917_5	518766.Rmar_1517	1.853e-06	60.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1FJ24@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
XH1_k127_832917_2	243231.GSU1941	4.991e-54	217.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,42PTN@68525|delta/epsilon subdivisions,2WKBJ@28221|Deltaproteobacteria,43SC3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c
XH1_k127_832917_0	1499967.BAYZ01000074_gene2110	8.994e-147	478.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	atoC	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH1_k127_832917_6	717606.PaecuDRAFT_4732	1.468e-05	55.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes	1239|Firmicutes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
XH1_k127_832917_4	1123488.ATUF01000004_gene1661	2.49e-12	72.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4D5RM@85005|Actinomycetales	201174|Actinobacteria	T	FHA domain protein	garA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
XH1_k127_832917_3	880073.Calab_2071	2.483e-27	131.0	COG1361@1|root,COG1404@1|root,COG1520@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG1520@2|Bacteria,2NQX6@2323|unclassified Bacteria	2|Bacteria	O	SPTR Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.1.3.1	ko:K01113,ko:K14645,ko:K17713	ko00790,ko01100,ko02020,ko02024,map00790,map01100,map02020,map02024	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03110	1.B.33.1	-	-	PKD,Peptidase_S8,SBBP
XH1_k127_832917_1	313606.M23134_05227	7.947e-97	358.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
XH1_k127_8352033_1	861299.J421_3101	9.969e-23	106.0	COG0621@1|root,COG0621@2|Bacteria,1ZT0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
XH1_k127_8352033_0	56780.SYN_00797	1.816e-89	308.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,2MQCJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	MiaB-like tRNA modifying enzyme	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
XH1_k127_8400827_1	395494.Galf_0927	5.344e-11	72.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,2VIMD@28216|Betaproteobacteria,44WBF@713636|Nitrosomonadales	28216|Betaproteobacteria	MU	Outer membrane efflux protein	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
XH1_k127_8400827_0	555079.Toce_1642	1.302e-285	895.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,42F4D@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
XH1_k127_8433001_6	153721.MYP_2146	2.825e-78	269.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47K8G@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
XH1_k127_8433001_2	1380384.JADN01000004_gene2038	7.614e-225	704.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
XH1_k127_8433001_5	1499967.BAYZ01000159_gene484	7.312e-98	329.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
XH1_k127_8433001_0	330214.NIDE2036	5.532e-244	778.0	COG0272@1|root,COG0272@2|Bacteria,3J0W8@40117|Nitrospirae	40117|Nitrospirae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
XH1_k127_8433001_3	1229172.JQFA01000002_gene3738	4e-170	565.0	COG1449@1|root,COG1449@2|Bacteria,1G0BM@1117|Cyanobacteria,1H9KC@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
XH1_k127_8433001_1	247490.KSU1_D0142	5.163e-238	747.0	COG1543@1|root,COG1543@2|Bacteria,2J2W9@203682|Planctomycetes	203682|Planctomycetes	G	Domain of unknown function (DUF1957)	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
XH1_k127_8433001_7	886293.Sinac_6872	7.034e-50	194.0	COG3330@1|root,COG3330@2|Bacteria,2IWVT@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912,Rho_N
XH1_k127_8433001_11	459349.CLOAM0061	1.47e-20	108.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	wprA	-	3.1.3.6,3.1.4.16,3.2.1.99	ko:K01119,ko:K06113,ko:K12685,ko:K20276	ko00230,ko00240,ko02024,map00230,map00240,map02024	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Mucin_bdg,Peptidase_M60,Peptidase_S8,SLH
XH1_k127_8433001_8	880073.Calab_3409	1.724e-44	181.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	DUF4912,PBP_like_2
XH1_k127_8433001_9	530564.Psta_4322	6.372e-40	158.0	COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes	203682|Planctomycetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
XH1_k127_8433001_4	644966.Tmar_0705	3.245e-129	445.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,24BT1@186801|Clostridia,3WD7J@538999|Clostridiales incertae sedis	186801|Clostridia	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
XH1_k127_8433001_10	1379698.RBG1_1C00001G0345	2.445e-35	141.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
XH1_k127_849616_3	448385.sce5790	1.195e-40	158.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YUS3@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter, ATP-binding protein	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH1_k127_849616_2	330214.NIDE3434	4.622e-41	169.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
XH1_k127_849616_5	251221.35212822	2.023e-11	77.0	COG0457@1|root,COG0457@2|Bacteria,1G3FG@1117|Cyanobacteria	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_849616_1	338963.Pcar_2139	1.974e-58	213.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
XH1_k127_849616_0	290397.Adeh_0641	4.919e-75	266.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
XH1_k127_849616_7	671143.DAMO_1411	1.413e-09	66.0	COG3166@1|root,COG3166@2|Bacteria	2|Bacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02662,ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
XH1_k127_849616_4	1167006.UWK_00797	2.851e-21	102.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MJVB@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
XH1_k127_849616_8	1144275.COCOR_05330	1.734e-06	56.0	COG3064@1|root,COG3064@2|Bacteria,1NCIT@1224|Proteobacteria,431YH@68525|delta/epsilon subdivisions,2WWR8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	AMIN,TPR_6
XH1_k127_8499221_5	1499967.BAYZ01000185_gene4532	1.351e-16	87.0	COG2162@1|root,COG2162@2|Bacteria	2|Bacteria	Q	arylamine N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_2
XH1_k127_8499221_3	1185876.BN8_01524	1.085e-90	314.0	COG0153@1|root,COG0153@2|Bacteria,4NFSD@976|Bacteroidetes,47K00@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the GHMP kinase family	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
XH1_k127_8499221_4	929703.KE386491_gene1578	1.906e-72	254.0	COG1208@1|root,COG1208@2|Bacteria,4PJQ6@976|Bacteroidetes,47P7C@768503|Cytophagia	976|Bacteroidetes	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
XH1_k127_8499221_2	555779.Dthio_PD2268	2.458e-114	383.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42QFH@68525|delta/epsilon subdivisions,2WKWR@28221|Deltaproteobacteria,2M7U5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Glycos_transf_2,Radical_SAM
XH1_k127_8499221_0	485915.Dret_1750	4.949e-243	775.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
XH1_k127_8499221_1	1047013.AQSP01000075_gene1424	1.327e-159	538.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
XH1_k127_8544622_10	263358.VAB18032_04525	0.0002306	49.0	COG3311@1|root,COG3311@2|Bacteria,2GWWS@201174|Actinobacteria,4DGMD@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
XH1_k127_8544622_11	378753.KRH_08890	0.0003157	46.0	COG3311@1|root,COG3311@2|Bacteria,2GR98@201174|Actinobacteria,1WA6S@1268|Micrococcaceae	201174|Actinobacteria	K	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
XH1_k127_8544622_3	472759.Nhal_1036	1.551e-74	266.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1WYP2@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
XH1_k127_8544622_6	1123267.JONN01000001_gene1239	9.568e-25	116.0	2C1YS@1|root,2ZD2Y@2|Bacteria	2|Bacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
XH1_k127_8544622_0	1123267.JONN01000001_gene1238	1.991e-220	718.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MRJP
XH1_k127_8544622_5	1157490.EL26_06375	1.381e-31	130.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,278K5@186823|Alicyclobacillaceae	91061|Bacilli	K	Sigma-70, region 4	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH1_k127_8544622_8	319225.Plut_0862	4.722e-10	64.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	btrV	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	MEDS,STAS,STAS_2
XH1_k127_8544622_7	794903.OPIT5_07165	3.515e-11	69.0	COG2172@1|root,COG2172@2|Bacteria,46TBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
XH1_k127_8544622_1	1379698.RBG1_1C00001G0520	3.862e-104	353.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	CHASE2,GAF,GAF_2,HATPase_c_2,SpoIIE
XH1_k127_8544622_4	329726.AM1_2222	3e-74	260.0	COG2905@1|root,COG2905@2|Bacteria,1GPZ1@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
XH1_k127_8544622_2	1123288.SOV_4c03760	1.304e-92	336.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H2CW@909932|Negativicutes	909932|Negativicutes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
XH1_k127_8621099_10	331678.Cphamn1_1234	7.823e-44	170.0	COG0573@1|root,COG0573@2|Bacteria,1FE1M@1090|Chlorobi	1090|Chlorobi	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstC	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
XH1_k127_8621099_6	194439.CT0895	4.935e-85	291.0	COG0226@1|root,COG0226@2|Bacteria,1FF16@1090|Chlorobi	1090|Chlorobi	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
XH1_k127_8621099_7	247634.GPB2148_3470	2.241e-50	194.0	COG2188@1|root,COG2188@2|Bacteria,1QVF7@1224|Proteobacteria,1S5D3@1236|Gammaproteobacteria,1J8FY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Putative porin	-	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Porin_5
XH1_k127_8621099_0	1232410.KI421421_gene3404	3.885e-176	569.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43SD2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like
XH1_k127_8621099_1	880072.Desac_2636	4.669e-100	332.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
XH1_k127_8621099_11	871968.DESME_02320	1.437e-38	150.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,2657X@186807|Peptococcaceae	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
XH1_k127_8621099_5	251221.35211024	4.862e-86	300.0	COG0438@1|root,COG0438@2|Bacteria,1G1X1@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
XH1_k127_8621099_3	880073.Calab_2079	1.772e-89	310.0	COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
XH1_k127_8621099_2	1382359.JIAL01000001_gene3045	5.195e-94	317.0	COG4152@1|root,COG4152@2|Bacteria,3Y2NV@57723|Acidobacteria,2JHVX@204432|Acidobacteriia	204432|Acidobacteriia	S	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
XH1_k127_8621099_9	401526.TcarDRAFT_1170	1.869e-48	191.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4H4DD@909932|Negativicutes	909932|Negativicutes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
XH1_k127_8621099_4	316067.Geob_1363	2.486e-87	297.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
XH1_k127_8621099_12	644966.Tmar_0613	1.7e-16	89.0	COG5401@1|root,COG5401@2|Bacteria,1V64H@1239|Firmicutes	1239|Firmicutes	S	PFAM Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
XH1_k127_8621099_8	1379698.RBG1_1C00001G0723	2.473e-49	186.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
XH1_k127_8623704_4	1125863.JAFN01000001_gene2836	6.005e-58	207.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WNNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
XH1_k127_8623704_1	1125863.JAFN01000001_gene2835	4.195e-115	399.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
XH1_k127_8623704_0	1125863.JAFN01000001_gene2834	1.533e-125	415.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
XH1_k127_8623704_3	933262.AXAM01000011_gene1757	6.746e-109	378.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MJ2R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
XH1_k127_8623704_7	1131269.AQVV01000007_gene990	3.763e-05	52.0	COG4967@1|root,COG4967@2|Bacteria	2|Bacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02458,ko:K02671	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	N_methyl
XH1_k127_8623704_5	269799.Gmet_3524	6.034e-42	169.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,42TVP@68525|delta/epsilon subdivisions,2WQ7U@28221|Deltaproteobacteria,43UR2@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
XH1_k127_8623704_6	1530186.JQEY01000001_gene893	1.456e-06	54.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
XH1_k127_8623704_2	635013.TherJR_0068	3.084e-110	370.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,2602Z@186807|Peptococcaceae	186801|Clostridia	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
XH1_k127_8673291_8	1125863.JAFN01000001_gene1615	2.908e-84	289.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM magnesium chelatase ChlI subunit	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
XH1_k127_8673291_6	1379698.RBG1_1C00001G0709	2.075e-92	314.0	COG1899@1|root,COG1899@2|Bacteria,2NR8I@2323|unclassified Bacteria	2|Bacteria	O	Deoxyhypusine synthase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
XH1_k127_8673291_16	1167006.UWK_00574	2.33e-46	184.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42NBC@68525|delta/epsilon subdivisions,2WIMR@28221|Deltaproteobacteria,2MIAP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
XH1_k127_8673291_12	1379698.RBG1_1C00001G0710	4.136e-68	237.0	COG1945@1|root,COG1945@2|Bacteria,2NP74@2323|unclassified Bacteria	2|Bacteria	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
XH1_k127_8673291_17	56780.SYN_02549	4.07e-44	175.0	COG2768@1|root,COG2768@2|Bacteria,1MXMK@1224|Proteobacteria,42M2Z@68525|delta/epsilon subdivisions,2WIN6@28221|Deltaproteobacteria,2MQ78@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Fe-S center protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_4,Fer4_6,Fer4_7,Fer4_9
XH1_k127_8673291_4	880073.Calab_1667	1.154e-139	466.0	COG1757@1|root,COG1757@2|Bacteria,2NPD8@2323|unclassified Bacteria	2|Bacteria	C	Na+/H+ antiporter family	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
XH1_k127_8673291_3	479434.Sthe_3162	1.333e-140	467.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,2G64U@200795|Chloroflexi	200795|Chloroflexi	P	YidE YbjL duplication domain protein	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
XH1_k127_8673291_20	102232.GLO73106DRAFT_00035350	9.457e-12	70.0	COG0640@1|root,COG0640@2|Bacteria,1G6V5@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
XH1_k127_8673291_21	717231.Flexsi_0899	1.559e-09	64.0	COG2331@1|root,COG2331@2|Bacteria,2GG63@200930|Deferribacteres	200930|Deferribacteres	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
XH1_k127_8673291_2	1209989.TepiRe1_1817	1.211e-143	475.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
XH1_k127_8673291_7	997346.HMPREF9374_4006	9.015e-92	314.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,4HADK@91061|Bacilli,27B4Y@186824|Thermoactinomycetaceae	91061|Bacilli	EH	Acetohydroxy acid isomeroreductase, catalytic domain	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
XH1_k127_8673291_11	429009.Adeg_2060	1.763e-68	261.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,42F58@68295|Thermoanaerobacterales	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
XH1_k127_8673291_14	1259795.ARJK01000003_gene741	4.761e-51	189.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,42G9G@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
XH1_k127_8673291_0	1379698.RBG1_1C00001G1627	3.164e-229	727.0	COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
XH1_k127_8673291_5	1125863.JAFN01000001_gene2162	8.477e-96	328.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
XH1_k127_8673291_13	1123376.AUIU01000011_gene928	2.705e-66	239.0	COG1624@1|root,COG1624@2|Bacteria,3J0XP@40117|Nitrospirae	40117|Nitrospirae	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
XH1_k127_8673291_9	644282.Deba_2013	1.988e-73	266.0	COG0745@1|root,COG2203@1|root,COG2206@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
XH1_k127_8673291_18	926569.ANT_02070	4.832e-35	154.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi	200795|Chloroflexi	T	phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
XH1_k127_8673291_22	439497.RR11_881	1.291e-08	61.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,2UM3F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
XH1_k127_8673291_23	1090318.ATTI01000001_gene1562	0.0002308	54.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,2K0Z1@204457|Sphingomonadales	204457|Sphingomonadales	NT	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
XH1_k127_8673291_10	247490.KSU1_C1165	2.364e-73	256.0	COG0388@1|root,COG0388@2|Bacteria,2IXKW@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
XH1_k127_8673291_19	1122947.FR7_1836	4.783e-15	87.0	COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4H3ZP@909932|Negativicutes	909932|Negativicutes	S	Serine aminopeptidase, S33	est	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
XH1_k127_8673291_15	1047013.AQSP01000076_gene1478	6.413e-48	181.0	COG1600@1|root,COG1600@2|Bacteria,2NRKC@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_16,Fer4_7
XH1_k127_8673291_1	246194.CHY_1176	1.701e-185	589.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,42EYV@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
XH1_k127_8788768_5	880072.Desac_0018	1.364e-64	228.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2MQX1@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
XH1_k127_8788768_0	357808.RoseRS_3775	3.437e-122	406.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi,374SC@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_8788768_4	706587.Desti_4119	9.602e-71	249.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42R18@68525|delta/epsilon subdivisions,2WN0H@28221|Deltaproteobacteria,2MRMP@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	endonuclease III	nth	-	3.1.11.2,4.2.99.18	ko:K01142,ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,Exo_endo_phos,HhH-GPD
XH1_k127_8788768_1	945713.IALB_2248	4.061e-115	385.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
XH1_k127_8788768_8	604354.TSIB_1892	7.806e-17	88.0	COG1633@1|root,arCOG01103@2157|Archaea,2Y1BE@28890|Euryarchaeota,243JF@183968|Thermococci	183968|Thermococci	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_8788768_7	909663.KI867150_gene391	2.438e-31	133.0	COG1633@1|root,COG1633@2|Bacteria,1NG4N@1224|Proteobacteria,42W3T@68525|delta/epsilon subdivisions,2WREZ@28221|Deltaproteobacteria,2MRRS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH1_k127_8788768_3	517418.Ctha_2098	3.756e-74	256.0	COG1028@1|root,COG1028@2|Bacteria,1FEYT@1090|Chlorobi	1090|Chlorobi	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
XH1_k127_8788768_2	1382306.JNIM01000001_gene2674	1.37e-103	349.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	200795|Chloroflexi	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
XH1_k127_8788768_6	370438.PTH_0469	3.972e-48	182.0	COG1163@1|root,COG1163@2|Bacteria,1TSAP@1239|Firmicutes,24EEW@186801|Clostridia,260UT@186807|Peptococcaceae	186801|Clostridia	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
XH1_k127_942822_2	574087.Acear_0772	0.0003874	48.0	COG0810@1|root,COG0810@2|Bacteria,1VN7X@1239|Firmicutes,25413@186801|Clostridia,3WC1R@53433|Halanaerobiales	186801|Clostridia	M	TIGRFAM TonB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
XH1_k127_942822_3	573413.Spirs_2081	0.0004627	52.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
XH1_k127_942822_0	1047013.AQSP01000092_gene323	4.14e-197	620.0	COG0798@1|root,COG0798@2|Bacteria,2NNWJ@2323|unclassified Bacteria	2|Bacteria	P	Sodium Bile acid symporter family	arsB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
XH1_k127_942822_1	290397.Adeh_1548	1.305e-34	143.0	COG3115@1|root,COG3115@2|Bacteria,1QW35@1224|Proteobacteria,42UFZ@68525|delta/epsilon subdivisions,2WR5D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
XH1_k127_990413_9	1301098.PKB_3049	0.0009869	49.0	COG0457@1|root,COG3087@1|root,COG0457@2|Bacteria,COG3087@2|Bacteria,1MVB8@1224|Proteobacteria,1RPSN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Cellulose synthase	bcsC	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,TPR_16,TPR_19,TPR_8
XH1_k127_990413_1	387631.Asulf_01688	9.598e-118	403.0	COG0247@1|root,arCOG00332@2157|Archaea,2XTPG@28890|Euryarchaeota,245NQ@183980|Archaeoglobi	183980|Archaeoglobi	C	to GP 1890198 percent identity	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8,Nitrate_red_gam
XH1_k127_990413_3	1125863.JAFN01000001_gene2932	2.063e-72	254.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42PYM@68525|delta/epsilon subdivisions,2WJ37@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
XH1_k127_990413_4	1125863.JAFN01000001_gene2933	6.019e-69	245.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42MH7@68525|delta/epsilon subdivisions,2WK12@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
XH1_k127_990413_0	439235.Dalk_3317	1.524e-163	524.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJUN@28221|Deltaproteobacteria,2MIK6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH1_k127_990413_8	1382358.JHVN01000006_gene219	1.339e-07	60.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,21VRR@150247|Anoxybacillus	91061|Bacilli	CO	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
XH1_k127_990413_5	204669.Acid345_4032	3.6e-63	240.0	COG2972@1|root,COG2972@2|Bacteria,3Y3NH@57723|Acidobacteria,2JHT4@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,His_kinase
XH1_k127_990413_6	207559.Dde_0161	2.915e-45	187.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria,2MGW8@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator	yehT	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
XH1_k127_990413_2	1121428.DESHY_160143___1	2.449e-114	385.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,260ZD@186807|Peptococcaceae	186801|Clostridia	C	pyridine nucleotide-disulphide oxidoreductase dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
XH1_k127_990413_7	1123371.ATXH01000004_gene1748	3.269e-27	130.0	COG0612@1|root,COG0612@2|Bacteria,2GH66@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
## 2080 queries scanned
## Total time (seconds): 274.49860191345215
## Rate: 7.58 q/s