## Fri Feb 20 02:54:22 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/XH3_bin.18.fa -m mmseqs --output XH3_bin.18 --output_dir /data/result/bins/wyx/eggqs50+/XH3_bin.18 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
XH3_k127_1020646_1	313596.RB2501_02390	8.696e-23	109.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
XH3_k127_1020646_2	435591.BDI_1026	1.507e-22	100.0	COG4828@1|root,COG4828@2|Bacteria,4P3MD@976|Bacteroidetes,2G2GP@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
XH3_k127_1020646_0	439481.Aboo_0966	1.328e-172	555.0	COG1690@1|root,arCOG04246@2157|Archaea,2XTIC@28890|Euryarchaeota,3F2GK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	tRNA-splicing ligase RtcB	rtcB	GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Intein_splicing,LAGLIDADG_3,RtcB
XH3_k127_1020646_3	1120972.AUMH01000003_gene2940	1.19e-09	60.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,27977@186823|Alicyclobacillaceae	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
XH3_k127_1045027_4	880073.Calab_0112	1.349e-13	78.0	COG4775@1|root,COG4775@2|Bacteria,2NPNI@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
XH3_k127_1045027_2	1121930.AQXG01000002_gene2035	5.925e-46	176.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1IPDJ@117747|Sphingobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
XH3_k127_1045027_3	638303.Thal_0278	1.209e-14	77.0	COG1550@1|root,COG1550@2|Bacteria,2G47V@200783|Aquificae	200783|Aquificae	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
XH3_k127_1045027_0	1121430.JMLG01000001_gene2148	1.217e-188	613.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
XH3_k127_1045027_1	1379698.RBG1_1C00001G1152	1.304e-92	322.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
XH3_k127_1045027_5	1267535.KB906767_gene3804	0.0001155	49.0	COG0779@1|root,COG0779@2|Bacteria,3Y528@57723|Acidobacteria	57723|Acidobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
XH3_k127_105197_4	1220534.B655_0146	1.534e-18	95.0	COG0518@1|root,arCOG00087@2157|Archaea,2XT3G@28890|Euryarchaeota,23NYX@183925|Methanobacteria	183925|Methanobacteria	F	Catalyzes the synthesis of GMP from XMP	guaAA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
XH3_k127_105197_0	1232410.KI421422_gene2012	4.977e-82	282.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,42N4U@68525|delta/epsilon subdivisions,2WJR7@28221|Deltaproteobacteria,43SD4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Type I GTP cyclohydrolase folE2	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
XH3_k127_105197_2	909663.KI867149_gene3220	3.743e-58	210.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,2MQKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
XH3_k127_105197_1	269799.Gmet_1723	7.877e-79	267.0	arCOG10401@1|root,2ZA7Y@2|Bacteria,1R45R@1224|Proteobacteria,42MDG@68525|delta/epsilon subdivisions,2WKTC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_105197_3	330214.NIDE3327	1.028e-21	98.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
XH3_k127_1085200_0	457570.Nther_2432	9.614e-36	148.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia	186801|Clostridia	M	Competence protein ComEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Cu_amine_oxidN1,HHH_3,Lactamase_B
XH3_k127_1085200_1	1306174.JODP01000005_gene1309	5.315e-25	109.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
XH3_k127_1099691_2	880073.Calab_2073	5.882e-07	63.0	2E09V@1|root,32VXB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_1099691_1	1131730.BAVI_18789	3.421e-07	62.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,1ZBST@1386|Bacillus	91061|Bacilli	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
XH3_k127_1099691_0	555079.Toce_0772	3.461e-123	402.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,42ER6@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
XH3_k127_1117912_0	1341181.FLJC2902T_28130	2.219e-51	194.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1IEI1@117743|Flavobacteriia,2NUF7@237|Flavobacterium	976|Bacteroidetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
XH3_k127_1117912_1	1047013.AQSP01000073_gene1092	1.377e-23	114.0	COG1305@1|root,COG3391@1|root,COG1305@2|Bacteria,COG3391@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Transglut_core
XH3_k127_116468_0	926550.CLDAP_07830	1.317e-48	190.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
XH3_k127_116468_1	926550.CLDAP_07830	4.739e-09	63.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
XH3_k127_1169489_0	1111479.AXAR01000007_gene922	1.546e-127	416.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,2786R@186823|Alicyclobacillaceae	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
XH3_k127_1169489_2	658088.HMPREF0987_00474	7.777e-28	120.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,27MRB@186928|unclassified Lachnospiraceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
XH3_k127_1169489_3	660470.Theba_1556	1.775e-25	111.0	COG0817@1|root,COG0817@2|Bacteria,2GD6C@200918|Thermotogae	200918|Thermotogae	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
XH3_k127_1169489_1	1499967.BAYZ01000068_gene1977	4.174e-81	278.0	COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
XH3_k127_1202616_3	1485544.JQKP01000002_gene1648	1.929e-05	51.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,44VJ8@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
XH3_k127_1202616_0	349520.PPE_00061	9.107e-30	128.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,26RR9@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
XH3_k127_1202616_1	760568.Desku_3202	2.225e-28	124.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,260CI@186807|Peptococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
XH3_k127_1202616_2	518766.Rmar_1484	1.641e-07	62.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Kelch_4
XH3_k127_1218956_0	1449126.JQKL01000002_gene1552	8.497e-110	363.0	COG3259@1|root,COG3259@2|Bacteria,1UZNV@1239|Firmicutes,24F0H@186801|Clostridia	186801|Clostridia	C	PFAM Nickel-dependent hydrogenase, large subunit	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
XH3_k127_1218956_1	880073.Calab_3044	1.602e-109	363.0	COG1941@1|root,COG1941@2|Bacteria,2NQP6@2323|unclassified Bacteria	2|Bacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_lg_C,Fer4,FlpD,Oxidored_q6
XH3_k127_1218956_2	682795.AciX8_1470	0.0002172	51.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH3_k127_1243448_2	1157490.EL26_17660	0.0001673	53.0	COG4325@1|root,COG4325@2|Bacteria,1VTWI@1239|Firmicutes,4HTB9@91061|Bacilli,2792H@186823|Alicyclobacillaceae	91061|Bacilli	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
XH3_k127_1243448_1	1151117.AJLF01000002_gene152	1.165e-26	114.0	COG1917@1|root,arCOG02994@2157|Archaea,2Y8FP@28890|Euryarchaeota,245HX@183968|Thermococci	183968|Thermococci	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
XH3_k127_1243448_0	234267.Acid_3617	4.118e-41	162.0	COG4758@1|root,COG4758@2|Bacteria,3Y7Z2@57723|Acidobacteria	57723|Acidobacteria	S	N-terminal domain of toast_rack, DUF2154	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
XH3_k127_1245376_1	1242864.D187_000579	1.063e-12	81.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria,430Q8@68525|delta/epsilon subdivisions,2WVYQ@28221|Deltaproteobacteria,2YU06@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
XH3_k127_1245376_0	439235.Dalk_1475	4.156e-31	140.0	COG1470@1|root,COG4733@1|root,COG1470@2|Bacteria,COG4733@2|Bacteria,1QW0V@1224|Proteobacteria,42U6C@68525|delta/epsilon subdivisions,2WQX8@28221|Deltaproteobacteria,2MN90@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_2,DUF4215
XH3_k127_1245376_2	1267534.KB906756_gene287	1.828e-06	51.0	COG1012@1|root,COG1012@2|Bacteria,3Y37W@57723|Acidobacteria,2JHJP@204432|Acidobacteriia	204432|Acidobacteriia	C	Delta-1-pyrroline-5-carboxylate dehydrogenase	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
XH3_k127_1249280_2	525904.Tter_2363	5.255e-34	136.0	COG1956@1|root,COG1956@2|Bacteria,2NPKF@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
XH3_k127_1249280_0	357808.RoseRS_2644	3.724e-120	396.0	COG2309@1|root,COG2309@2|Bacteria,2G5TH@200795|Chloroflexi,376Y0@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
XH3_k127_1249280_1	633148.Tagg_0282	8.487e-39	146.0	COG2309@1|root,arCOG01888@2157|Archaea,2XPZP@28889|Crenarchaeota	28889|Crenarchaeota	E	peptidase M29 aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
XH3_k127_1250036_1	983545.Glaag_0849	0.0002626	45.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,464DY@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
XH3_k127_1250036_0	1450694.BTS2_3063	1.932e-94	321.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,1ZC2F@1386|Bacillus	91061|Bacilli	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
XH3_k127_1253531_1	743722.Sph21_1077	1.65e-06	59.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1IPQ3@117747|Sphingobacteriia	976|Bacteroidetes	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
XH3_k127_1253531_0	555079.Toce_2268	7.752e-42	160.0	COG0739@1|root,COG4487@1|root,COG0739@2|Bacteria,COG4487@2|Bacteria,1V3ZU@1239|Firmicutes,24JM4@186801|Clostridia,42FFZ@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
XH3_k127_1258540_0	525903.Taci_1366	9.327e-115	378.0	COG0065@1|root,COG0065@2|Bacteria,3TA6N@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
XH3_k127_1258540_1	1047013.AQSP01000140_gene2451	1.977e-50	184.0	COG0066@1|root,COG0066@2|Bacteria,2NPKG@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
XH3_k127_1325464_0	1379698.RBG1_1C00001G1247	4.17e-146	472.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
XH3_k127_1325464_3	272558.10172917	1.71e-16	83.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
XH3_k127_1325464_2	118168.MC7420_6518	5.558e-36	156.0	COG0823@1|root,COG1404@1|root,COG2931@1|root,COG0823@2|Bacteria,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B
XH3_k127_1325464_1	459349.CLOAM0313	1.393e-74	277.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,DUF3857,GBS_Bsp-like,Transglut_core
XH3_k127_1340674_1	880073.Calab_0832	0.0001193	46.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Cna_B,Cu_amine_oxidN1,PSII_BNR,SLH
XH3_k127_1340674_0	215803.DB30_7610	2.561e-76	286.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
XH3_k127_135445_1	518766.Rmar_1450	3.026e-60	226.0	COG0642@1|root,COG2205@2|Bacteria,4PKGE@976|Bacteroidetes,1FIRF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
XH3_k127_135445_0	1121104.AQXH01000006_gene2304	2.067e-125	418.0	COG0745@1|root,COG0745@2|Bacteria,4PM6N@976|Bacteroidetes,1J10G@117747|Sphingobacteriia	976|Bacteroidetes	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
XH3_k127_1364997_0	1121468.AUBR01000040_gene1729	5.735e-263	831.0	COG1148@1|root,COG1249@1|root,COG1148@2|Bacteria,COG1249@2|Bacteria,1V5YJ@1239|Firmicutes,248CC@186801|Clostridia,42FJG@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
XH3_k127_1364997_2	868131.MSWAN_1553	2.873e-13	79.0	COG2048@1|root,arCOG00964@2157|Archaea,2XXYP@28890|Euryarchaeota,23NZ8@183925|Methanobacteria	183925|Methanobacteria	C	reductase, subunit	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_8
XH3_k127_1364997_1	1121430.JMLG01000014_gene1960	6.293e-19	96.0	COG0247@1|root,COG0247@2|Bacteria,1UY5V@1239|Firmicutes,24DSV@186801|Clostridia,264AI@186807|Peptococcaceae	186801|Clostridia	C	PFAM Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
XH3_k127_1406250_3	1045004.OKIT_0446	1.501e-08	58.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,4AWUW@81850|Leuconostocaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
XH3_k127_1406250_1	717605.Theco_3756	6.141e-23	110.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,26QB9@186822|Paenibacillaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
XH3_k127_1406250_2	1123507.ATVQ01000001_gene1928	6.512e-09	61.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,1W9C5@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
XH3_k127_1406250_0	1379698.RBG1_1C00001G0271	4.841e-156	501.0	COG0187@1|root,COG0187@2|Bacteria,2NNSN@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
XH3_k127_1462250_1	215358.XP_010755272.1	3.835e-06	61.0	KOG0379@1|root,KOG0379@2759|Eukaryota,39U3E@33154|Opisthokonta,3BNR9@33208|Metazoa,3D02V@33213|Bilateria,48CR7@7711|Chordata,4987T@7742|Vertebrata,49SQU@7898|Actinopterygii	33208|Metazoa	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_5,Kelch_6
XH3_k127_1462250_0	1379698.RBG1_1C00001G0217	7.4e-62	242.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
XH3_k127_150337_0	1157490.EL26_06940	1.388e-79	283.0	COG0312@1|root,COG0312@2|Bacteria,1TSQC@1239|Firmicutes,4HA0D@91061|Bacilli	91061|Bacilli	S	Zn-dependent proteases and their inactivated homologs	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
XH3_k127_150337_2	1415778.JQMM01000001_gene1856	1.187e-07	61.0	COG0454@1|root,COG0456@2|Bacteria,1RG94@1224|Proteobacteria,1S4UT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
XH3_k127_150337_1	502025.Hoch_3647	2.696e-32	128.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
XH3_k127_151394_3	591019.Shell_0586	4.707e-44	172.0	COG2248@1|root,arCOG00969@2157|Archaea,2XQEH@28889|Crenarchaeota	28889|Crenarchaeota	S	Belongs to the UPF0282 family	-	-	-	ko:K07022	-	-	-	-	ko00000	-	-	-	Lactamase_B,Lactamase_B_2,Lactamase_B_3
XH3_k127_151394_4	309799.DICTH_1072	1.96e-31	134.0	COG4589@1|root,COG4589@2|Bacteria	2|Bacteria	S	phosphatidate cytidylyltransferase activity	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
XH3_k127_151394_0	240016.ABIZ01000001_gene1257	1.394e-76	264.0	COG0020@1|root,COG0020@2|Bacteria,46SMY@74201|Verrucomicrobia,2IU5V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
XH3_k127_151394_1	635013.TherJR_1359	1.462e-56	203.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,261N9@186807|Peptococcaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
XH3_k127_151394_2	314345.SPV1_05734	3.466e-51	189.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
XH3_k127_1516554_3	1379698.RBG1_1C00001G0327	7.299e-11	71.0	COG1664@1|root,COG1664@2|Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
XH3_k127_1516554_1	1121918.ARWE01000001_gene1360	1.127e-143	469.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2X70U@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	E	PFAM Cys Met metabolism	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
XH3_k127_1516554_0	903818.KI912268_gene822	4.001e-167	536.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
XH3_k127_1516554_2	1157490.EL26_09240	3.759e-14	74.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,4HBDK@91061|Bacilli,278T8@186823|Alicyclobacillaceae	91061|Bacilli	G	M42 glutamyl aminopeptidase	yhfE	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
XH3_k127_1528973_2	443143.GM18_3517	9.967e-29	119.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,43U4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
XH3_k127_1528973_0	1379698.RBG1_1C00001G1139	3.197e-119	401.0	COG0323@1|root,COG0323@2|Bacteria,2NNP7@2323|unclassified Bacteria	2|Bacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
XH3_k127_1528973_1	1379698.RBG1_1C00001G0171	3.283e-48	181.0	COG1235@1|root,COG1235@2|Bacteria,2NP81@2323|unclassified Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
XH3_k127_1536261_3	1121129.KB903359_gene2283	9.768e-31	128.0	COG3829@1|root,COG3829@2|Bacteria,4NUDP@976|Bacteroidetes,2FU2M@200643|Bacteroidia,22YF1@171551|Porphyromonadaceae	976|Bacteroidetes	KT	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
XH3_k127_1536261_1	667014.Thein_1148	2.022e-65	230.0	COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
XH3_k127_1536261_2	1122947.FR7_2585	1.052e-56	204.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4H4H3@909932|Negativicutes	909932|Negativicutes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
XH3_k127_1536261_0	439235.Dalk_3756	8.215e-106	353.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,42NWX@68525|delta/epsilon subdivisions,2WIZY@28221|Deltaproteobacteria,2MJ6T@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
XH3_k127_1570977_1	1000565.METUNv1_03262	3.162e-28	124.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,2KWCK@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
XH3_k127_1570977_0	589865.DaAHT2_1884	2.036e-78	273.0	COG3481@1|root,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria,2MICY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	nucleic acid binding OB-fold tRNA helicase-type	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
XH3_k127_1570977_2	1379698.RBG1_1C00001G0331	6.597e-18	91.0	COG2067@1|root,COG2067@2|Bacteria,2NPV7@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
XH3_k127_1588577_1	478741.JAFS01000002_gene757	6.505e-114	380.0	COG0519@1|root,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,37FXE@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
XH3_k127_1588577_0	869210.Marky_1980	3.708e-167	541.0	COG0495@1|root,COG0495@2|Bacteria,1WIX9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,Leucyl-specific,tRNA-synt_1,tRNA-synt_1_2
XH3_k127_1589122_0	123214.PERMA_0556	1.117e-179	571.0	COG0499@1|root,COG0499@2|Bacteria,2G3TI@200783|Aquificae	200783|Aquificae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
XH3_k127_1589122_1	1125863.JAFN01000001_gene892	2.489e-69	240.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
XH3_k127_160814_3	886293.Sinac_7569	9.456e-65	239.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
XH3_k127_160814_0	1047013.AQSP01000144_gene895	8.545e-170	545.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
XH3_k127_160814_7	266779.Meso_0155	4.552e-05	50.0	2AGY4@1|root,33HSC@2|Bacteria,1NJ83@1224|Proteobacteria,2UWQN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_160814_5	880073.Calab_0041	9.048e-07	62.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
XH3_k127_160814_2	595460.RRSWK_05050	2.013e-94	331.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
XH3_k127_160814_1	1408433.JHXV01000002_gene442	3.602e-134	447.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
XH3_k127_160814_6	880073.Calab_0913	4.496e-06	55.0	COG1523@1|root,COG1523@2|Bacteria	2|Bacteria	G	belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
XH3_k127_160814_4	391587.KAOT1_12237	2.268e-21	100.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
XH3_k127_162908_0	1379698.RBG1_1C00001G0217	1.843e-176	588.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
XH3_k127_162908_3	1333523.L593_03565	8.122e-06	57.0	arCOG08148@1|root,arCOG08148@2157|Archaea,2XYMA@28890|Euryarchaeota,23W7Q@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
XH3_k127_162908_1	996637.SGM_4595	4.092e-65	228.0	COG1131@1|root,COG1131@2|Bacteria,2GP3F@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
XH3_k127_162908_2	1121468.AUBR01000020_gene2852	2.915e-28	126.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,42EX6@68295|Thermoanaerobacterales	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
XH3_k127_1649972_1	880072.Desac_0008	1.249e-35	140.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2MS9G@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
XH3_k127_1649972_0	765420.OSCT_1823	2.311e-83	295.0	2E0CW@1|root,32VZR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_1649972_2	42099.EPrPV00000023086	0.0002645	47.0	2F35U@1|root,2T44T@2759|Eukaryota,1MGTP@121069|Pythiales	121069|Pythiales	S	function. Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
XH3_k127_1691566_0	1499967.BAYZ01000069_gene1846	6.171e-135	438.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
XH3_k127_1691566_1	1379698.RBG1_1C00001G1778	7.283e-86	298.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
XH3_k127_1714783_1	575540.Isop_0466	1.568e-38	148.0	COG1207@1|root,COG1207@2|Bacteria,2IXBV@203682|Planctomycetes	203682|Planctomycetes	M	Sugar nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_4
XH3_k127_1714783_0	1449126.JQKL01000070_gene3530	2.716e-62	227.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
XH3_k127_1749520_1	1117647.M5M_06570	3.298e-111	364.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1J4RS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0016874,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	iECW_1372.ECW_m3896,iEKO11_1354.EKO11_0103,iPC815.YPO0059,iWFL_1372.ECW_m3896	Aminotran_1_2
XH3_k127_1749520_2	665571.STHERM_c17760	3.092e-64	238.0	COG0274@1|root,COG0274@2|Bacteria,2J7GA@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
XH3_k127_1749520_5	1123242.JH636436_gene728	5.776e-06	60.0	COG0421@1|root,COG0421@2|Bacteria,2IZDV@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
XH3_k127_1749520_4	880073.Calab_0613	1.13e-29	133.0	COG1596@1|root,COG1596@2|Bacteria,2NPNM@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
XH3_k127_1749520_3	511051.CSE_04370	3.595e-40	160.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	upp	-	2.4.2.9,5.3.1.6	ko:K00761,ko:K01808	ko00030,ko00051,ko00240,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00240,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R00966,R01056,R09030	RC00063,RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB,UPRTase
XH3_k127_1749520_0	1128421.JAGA01000001_gene2171	6.569e-131	424.0	COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
XH3_k127_1749846_0	123214.PERMA_0937	7.047e-11	75.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
XH3_k127_1749846_1	887898.HMPREF0551_0629	6.12e-10	63.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,1K1RF@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
XH3_k127_1754124_5	909663.KI867150_gene2882	1.042e-31	125.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MREN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	nfnA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
XH3_k127_1754124_1	1232410.KI421421_gene3867	8.411e-77	267.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria,43SC0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
XH3_k127_1754124_6	269800.Tfu_2630	4.403e-27	116.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4EJ8X@85012|Streptosporangiales	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
XH3_k127_1754124_2	479434.Sthe_1053	3.614e-42	164.0	COG0098@1|root,COG0098@2|Bacteria,2G6M9@200795|Chloroflexi,27YA8@189775|Thermomicrobia	189775|Thermomicrobia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
XH3_k127_1754124_7	42256.RradSPS_1925	1.483e-12	71.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4CQVX@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
XH3_k127_1754124_3	555079.Toce_0137	1.807e-37	147.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
XH3_k127_1754124_0	1379698.RBG1_1C00001G1576	3.479e-140	458.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
XH3_k127_1754124_4	1379698.RBG1_1C00001G0627	6.464e-36	144.0	COG1595@1|root,COG1595@2|Bacteria,2NQ4E@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH3_k127_1754124_8	1121430.JMLG01000019_gene1643	1.451e-09	66.0	COG5662@1|root,COG5662@2|Bacteria,1VKS6@1239|Firmicutes,24VD1@186801|Clostridia	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
XH3_k127_1761539_1	236814.IX39_01955	2.284e-12	76.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1HZ3R@117743|Flavobacteriia,3ZP2T@59732|Chryseobacterium	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_1761539_0	521011.Mpal_0423	5.115e-23	112.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
XH3_k127_1780136_0	237368.SCABRO_03197	2.298e-196	626.0	COG0441@1|root,COG0441@2|Bacteria,2IXFR@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
XH3_k127_1780136_1	296591.Bpro_2715	1.125e-19	91.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,4ADJH@80864|Comamonadaceae	28216|Betaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
XH3_k127_1819846_0	1379698.RBG1_1C00001G1816	1.46e-57	223.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
XH3_k127_183257_1	1246995.AFR_27325	2.022e-09	68.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616,Exo_endo_phos
XH3_k127_183257_0	338966.Ppro_1599	8.994e-66	244.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,1MU0N@1224|Proteobacteria,43BK2@68525|delta/epsilon subdivisions,2X6XX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,PAS_4,PAS_9,Response_reg,Sigma54_activat
XH3_k127_1890176_0	439235.Dalk_2168	2.015e-23	116.0	COG0457@1|root,COG0457@2|Bacteria,1QZ63@1224|Proteobacteria,43CRW@68525|delta/epsilon subdivisions,2WU4X@28221|Deltaproteobacteria	1224|Proteobacteria	S	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
XH3_k127_1890176_1	459349.CLOAM0443	0.000154	49.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
XH3_k127_1899411_2	1047013.AQSP01000140_gene2513	6.851e-78	271.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
XH3_k127_1899411_4	391612.CY0110_20610	1.748e-13	81.0	COG2027@1|root,COG2027@2|Bacteria,1G0QN@1117|Cyanobacteria,3KFR9@43988|Cyanothece	1117|Cyanobacteria	M	PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
XH3_k127_1899411_1	246194.CHY_0906	3.68e-82	284.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,42G4Q@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
XH3_k127_1899411_5	518766.Rmar_0721	6.456e-06	60.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_1899411_0	671143.DAMO_0075	7.909e-94	320.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
XH3_k127_1899411_3	545694.TREPR_2441	1.007e-41	159.0	COG2227@1|root,COG2227@2|Bacteria,2J59U@203691|Spirochaetes	203691|Spirochaetes	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
XH3_k127_1906874_1	580332.Slit_2828	4.228e-54	193.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VJGY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_9,TarH
XH3_k127_1906874_0	555079.Toce_1646	1.541e-54	207.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42F65@68295|Thermoanaerobacterales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
XH3_k127_1916729_1	459349.CLOAM1019	7.441e-45	181.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	3.6.3.44	ko:K06147,ko:K06148,ko:K11085,ko:K16787,ko:K18104,ko:K18889	ko01501,ko02010,map01501,map02010	M00582,M00700,M00707	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	3.A.1,3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.117,3.A.1.123,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
XH3_k127_1916729_0	1304880.JAGB01000002_gene1549	6.569e-100	340.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
XH3_k127_1950581_3	608506.COB47_0574	9.787e-24	106.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,42EVQ@68295|Thermoanaerobacterales	186801|Clostridia	G	TIGRFAM bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
XH3_k127_1950581_0	273068.TTE2334	6.369e-134	447.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
XH3_k127_1950581_4	880073.Calab_1239	1.22e-22	100.0	COG1925@1|root,COG1925@2|Bacteria,2NQ15@2323|unclassified Bacteria	2|Bacteria	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
XH3_k127_1950581_2	1191523.MROS_2009	5.022e-42	162.0	COG1974@1|root,COG1974@2|Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
XH3_k127_1950581_5	247490.KSU1_C0242	1.03e-14	79.0	2EJQV@1|root,33DFP@2|Bacteria,2J3W4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_1950581_1	269799.Gmet_1441	2.306e-65	229.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,43T82@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
XH3_k127_1981734_5	479434.Sthe_1626	1.221e-05	48.0	COG1403@1|root,COG1403@2|Bacteria,2G6RY@200795|Chloroflexi,27Y84@189775|Thermomicrobia	189775|Thermomicrobia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
XH3_k127_1981734_3	1500890.JQNL01000001_gene130	3.031e-09	69.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1X5IM@135614|Xanthomonadales	135614|Xanthomonadales	NU	type IV pilus biogenesis stability protein PilW	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_10,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8
XH3_k127_1981734_1	1244869.H261_08628	5.001e-70	262.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,2JPAZ@204441|Rhodospirillales	204441|Rhodospirillales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
XH3_k127_1981734_4	555217.Zmob_0156	1.696e-06	62.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,2K0C4@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
XH3_k127_1981734_2	1499967.BAYZ01000088_gene5093	4.045e-33	147.0	COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
XH3_k127_1981734_0	204669.Acid345_1048	2.876e-236	743.0	COG2987@1|root,COG2987@2|Bacteria,3Y2VD@57723|Acidobacteria,2JK4Z@204432|Acidobacteriia	204432|Acidobacteriia	E	Urocanase Rossmann-like domain	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
XH3_k127_1981734_6	861299.J421_1965	2.35e-05	53.0	COG2020@1|root,COG2020@2|Bacteria,1ZU79@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
XH3_k127_1985323_0	243231.GSU2568	1.531e-79	280.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,43TX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	SMART Elongator protein 3 MiaB NifB	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
XH3_k127_1985323_1	459349.CLOAM1383	3.101e-13	81.0	COG2825@1|root,COG2825@2|Bacteria,2NQ6C@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
XH3_k127_1985323_2	247634.GPB2148_2927	3.612e-09	61.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1J554@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iPC815.YPO1056	Acetyltransf_11,Hexapep
XH3_k127_1995452_5	593750.Metfor_0743	4.084e-10	66.0	COG1520@1|root,COG3291@1|root,arCOG02516@1|root,arCOG02538@1|root,arCOG06792@1|root,arCOG09475@1|root,arCOG02482@2157|Archaea,arCOG02492@2157|Archaea,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,arCOG06792@2157|Archaea,arCOG09475@2157|Archaea,2Y7Q0@28890|Euryarchaeota,2NAJS@224756|Methanomicrobia	28890|Euryarchaeota	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PQQ_3
XH3_k127_1995452_0	525904.Tter_0977	0.0	1164.0	COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
XH3_k127_1995452_3	1379698.RBG1_1C00001G0104	1.342e-20	97.0	COG1734@1|root,COG1734@2|Bacteria,2NPX2@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulator, TraR DksA family	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
XH3_k127_1995452_2	1120746.CCNL01000008_gene592	1.791e-47	179.0	COG0101@1|root,COG0101@2|Bacteria,2NPEC@2323|unclassified Bacteria	2|Bacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
XH3_k127_1995452_1	243274.THEMA_01685	6.043e-55	208.0	COG1653@1|root,COG1653@2|Bacteria,2GC37@200918|Thermotogae	200918|Thermotogae	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
XH3_k127_1995452_4	1191523.MROS_1582	9.662e-11	70.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Fn3-like,Glyco_hydro_3_C,SLH
XH3_k127_1995452_6	1122222.AXWR01000016_gene2511	4.319e-05	48.0	COG1225@1|root,COG1225@2|Bacteria,1WI9E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
XH3_k127_1997476_0	1519464.HY22_04640	6.519e-48	177.0	COG1403@1|root,COG1403@2|Bacteria,1FDXZ@1090|Chlorobi	1090|Chlorobi	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
XH3_k127_1997476_1	880073.Calab_0112	3.607e-10	72.0	COG4775@1|root,COG4775@2|Bacteria,2NPNI@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
XH3_k127_2031250_3	457570.Nther_1202	3.399e-37	148.0	COG2928@1|root,COG2928@2|Bacteria,1V6FM@1239|Firmicutes,24JQ1@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
XH3_k127_2031250_1	335543.Sfum_3633	9.891e-44	166.0	2CA4A@1|root,32RQK@2|Bacteria,1RE4A@1224|Proteobacteria,42RRI@68525|delta/epsilon subdivisions,2WND4@28221|Deltaproteobacteria,2MRVV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
XH3_k127_2031250_2	1379698.RBG1_1C00001G1228	5.023e-38	156.0	COG1386@1|root,COG1386@2|Bacteria,2NPPM@2323|unclassified Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
XH3_k127_2031250_0	1121289.JHVL01000022_gene1145	5.11e-56	206.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,36EUA@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
XH3_k127_2041871_2	338963.Pcar_1722	2.559e-18	87.0	COG0502@1|root,COG0502@2|Bacteria,1R8GT@1224|Proteobacteria,42QNT@68525|delta/epsilon subdivisions,2WN06@28221|Deltaproteobacteria,43T1U@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
XH3_k127_2041871_1	338963.Pcar_1629	2.179e-171	547.0	COG0486@1|root,COG0486@2|Bacteria,1PM94@1224|Proteobacteria,42MYX@68525|delta/epsilon subdivisions,2WJE4@28221|Deltaproteobacteria,43TB1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Ferrous iron transport protein B	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
XH3_k127_2041871_0	338963.Pcar_1631	2.057e-185	590.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42Q6J@68525|delta/epsilon subdivisions,2WKXA@28221|Deltaproteobacteria,43TBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
XH3_k127_2094880_1	1379698.RBG1_1C00001G1562	1.163e-108	370.0	COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
XH3_k127_2094880_0	1125863.JAFN01000001_gene2931	9.29e-109	366.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8,Fer4_9,Nitrate_red_gam
XH3_k127_2151342_0	1499967.BAYZ01000007_gene5399	1.096e-26	121.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
XH3_k127_2161448_0	935948.KE386495_gene1083	6.342e-85	298.0	COG0477@1|root,COG0477@2|Bacteria,1UI7B@1239|Firmicutes,25ECI@186801|Clostridia,42J7J@68295|Thermoanaerobacterales	186801|Clostridia	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
XH3_k127_221416_2	595460.RRSWK_06974	5.165e-22	98.0	COG1404@1|root,COG3291@1|root,COG5337@1|root,COG5549@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria,COG5549@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
XH3_k127_221416_0	1122179.KB890435_gene931	1.413e-168	556.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
XH3_k127_221416_1	1121890.AUDO01000001_gene834	7.76e-27	116.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia,2NY8D@237|Flavobacterium	976|Bacteroidetes	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
XH3_k127_2234302_1	1047013.AQSP01000128_gene445	9.178e-20	102.0	COG2006@1|root,COG2006@2|Bacteria,2NPI6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
XH3_k127_2234302_0	879212.DespoDRAFT_02581	3.485e-47	177.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2MI7G@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
XH3_k127_2257547_0	40571.JOEA01000004_gene6196	9.449e-30	134.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,4E251@85010|Pseudonocardiales	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Cytochrom_D1,Lactonase
XH3_k127_2257547_1	661478.OP10G_4384	9.489e-24	117.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
XH3_k127_2257547_2	204669.Acid345_3583	3.572e-18	91.0	COG3391@1|root,COG3391@2|Bacteria,3Y7M7@57723|Acidobacteria,2JP55@204432|Acidobacteriia	2|Bacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Lactonase,VCBS
XH3_k127_2306045_5	401526.TcarDRAFT_1339	2.711e-10	66.0	COG1560@1|root,COG1560@2|Bacteria,1TT7A@1239|Firmicutes,4H33V@909932|Negativicutes	909932|Negativicutes	M	Lipid A biosynthesis	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
XH3_k127_2306045_4	335541.Swol_0911	3.621e-41	156.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,42K5I@68298|Syntrophomonadaceae	186801|Clostridia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
XH3_k127_2306045_0	309801.trd_1965	9.312e-68	249.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi,27XU5@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
XH3_k127_2306045_3	1121472.AQWN01000007_gene1116	1.485e-52	195.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,2609K@186807|Peptococcaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
XH3_k127_2306045_2	498761.HM1_0751	1.535e-54	201.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia	186801|Clostridia	L	hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
XH3_k127_2306045_1	880073.Calab_2044	1.259e-58	213.0	COG0143@1|root,COG0143@2|Bacteria,2NNTX@2323|unclassified Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
XH3_k127_2308081_4	926561.KB900617_gene1998	8.39e-21	93.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,24R29@186801|Clostridia,3WAXG@53433|Halanaerobiales	186801|Clostridia	O	PFAM NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU
XH3_k127_2308081_5	96561.Dole_1178	5.361e-13	81.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42MCH@68525|delta/epsilon subdivisions,2WJPZ@28221|Deltaproteobacteria,2MIEC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
XH3_k127_2308081_2	502025.Hoch_0351	2.323e-56	216.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YTYT@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
XH3_k127_2308081_1	1122951.ATUE01000007_gene788	6.948e-99	336.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,3NJ57@468|Moraxellaceae	1236|Gammaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188	DXPR_C,DXP_redisom_C,DXP_reductoisom
XH3_k127_2308081_3	1121428.DESHY_150011___1	3.059e-38	153.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,261YY@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
XH3_k127_2308081_0	572479.Hprae_0707	9.344e-139	449.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WADX@53433|Halanaerobiales	186801|Clostridia	J	PFAM tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
XH3_k127_2318818_0	880073.Calab_2071	5.806e-62	235.0	COG1361@1|root,COG1404@1|root,COG1520@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG1520@2|Bacteria,2NQX6@2323|unclassified Bacteria	2|Bacteria	O	SPTR Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.1.3.1	ko:K01113,ko:K14645,ko:K17713	ko00790,ko01100,ko02020,ko02024,map00790,map01100,map02020,map02024	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03110	1.B.33.1	-	-	PKD,Peptidase_S8,SBBP
XH3_k127_2383124_1	1211813.CAPH01000007_gene1830	2.07e-104	351.0	COG1070@1|root,COG1070@2|Bacteria,4NIJC@976|Bacteroidetes,2FP4C@200643|Bacteroidia	976|Bacteroidetes	G	Carbohydrate kinase, FGGY family protein	rhaB	GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	2.7.1.5,2.7.1.51	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014,R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
XH3_k127_2383124_0	243090.RB678	5.149e-164	526.0	COG4806@1|root,COG4806@2|Bacteria,2IXTQ@203682|Planctomycetes	203682|Planctomycetes	G	L-rhamnose isomerase	rhaA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
XH3_k127_2383124_2	471854.Dfer_3461	1.866e-33	140.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,47M3M@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
XH3_k127_2397355_2	459349.CLOAM0950	1.209e-25	113.0	COG0249@1|root,COG0249@2|Bacteria,2NNN6@2323|unclassified Bacteria	2|Bacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
XH3_k127_2397355_0	240016.ABIZ01000001_gene3227	1.259e-133	434.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
XH3_k127_2397355_3	1449126.JQKL01000013_gene3435	1.238e-20	102.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,268FA@186813|unclassified Clostridiales	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
XH3_k127_2397355_4	1268072.PSAB_18305	0.0006324	48.0	COG2891@1|root,COG2891@2|Bacteria,1VEN7@1239|Firmicutes,4HNWW@91061|Bacilli,26UQH@186822|Paenibacillaceae	91061|Bacilli	M	rod shape-determining protein MreD	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
XH3_k127_2397355_1	1379698.RBG1_1C00001G1003	2.369e-128	434.0	COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding protein 2	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
XH3_k127_2409460_1	1353529.M899_1716	1.843e-21	107.0	COG0312@1|root,COG0312@2|Bacteria,1QM7I@1224|Proteobacteria,432IZ@68525|delta/epsilon subdivisions,2MTJX@213481|Bdellovibrionales,2WYIA@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
XH3_k127_2409460_0	398767.Glov_0063	3.525e-146	478.0	COG0312@1|root,COG0312@2|Bacteria,1NSH6@1224|Proteobacteria,42SDI@68525|delta/epsilon subdivisions,2WP1J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
XH3_k127_2409460_2	880073.Calab_3481	6.866e-20	98.0	COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
XH3_k127_2429165_3	1469613.JT55_13220	5.286e-15	85.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
XH3_k127_2429165_2	234267.Acid_3827	7.819e-40	156.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_11
XH3_k127_2429165_0	319225.Plut_0429	3.074e-80	278.0	COG0463@1|root,COG0463@2|Bacteria,1FDBQ@1090|Chlorobi	1090|Chlorobi	M	PFAM glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
XH3_k127_2429165_1	1461694.ATO9_09705	2.457e-51	201.0	COG1807@1|root,COG1807@2|Bacteria,1Q255@1224|Proteobacteria,2V9M6@28211|Alphaproteobacteria,2PF7E@252301|Oceanicola	28211|Alphaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_2429165_4	1382306.JNIM01000001_gene3762	5.663e-12	78.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH3_k127_2435303_1	264732.Moth_1955	1.934e-148	479.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
XH3_k127_2435303_0	204669.Acid345_2237	4.917e-280	876.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
XH3_k127_2457884_0	448385.sce4026	3.116e-24	107.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HD,HisKA,PAS,Response_reg
XH3_k127_2457884_2	452637.Oter_1832	1.245e-07	62.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
XH3_k127_2457884_1	56780.SYN_02223	6.461e-16	83.0	COG0680@1|root,COG0680@2|Bacteria,1R3V7@1224|Proteobacteria	1224|Proteobacteria	C	maturation protease	hycI	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
XH3_k127_2469051_0	1379698.RBG1_1C00001G1737	6.89e-92	328.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
XH3_k127_2469051_1	880073.Calab_0291	1.87e-09	66.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
XH3_k127_2505995_0	123214.PERMA_0937	5.617e-06	53.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
XH3_k127_2512347_1	1379698.RBG1_1C00001G1319	7.768e-19	91.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
XH3_k127_2512347_0	1121445.ATUZ01000018_gene2298	1.185e-49	197.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJKZ@28221|Deltaproteobacteria,2M8TB@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH3_k127_2525017_2	945713.IALB_1063	3.881e-60	222.0	COG2812@1|root,COG2812@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
XH3_k127_2525017_1	1379698.RBG1_1C00001G1657	2.952e-63	226.0	COG0353@1|root,COG0353@2|Bacteria,2NP5N@2323|unclassified Bacteria	2|Bacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
XH3_k127_2525017_4	1336237.JAEE01000014_gene1413	1.536e-13	76.0	COG1544@1|root,COG1544@2|Bacteria,1RD2Y@1224|Proteobacteria,1S6GT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Sigma 54 modulation protein ribosomal protein S30EA	raiA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05809	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
XH3_k127_2525017_0	1379698.RBG1_1C00001G0553	7.731e-87	299.0	COG1493@1|root,COG1493@2|Bacteria,2NP5B@2323|unclassified Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
XH3_k127_2525017_5	592010.GCWU000182_000345	0.0005006	48.0	COG2893@1|root,COG2893@2|Bacteria,1VES9@1239|Firmicutes,4HS07@91061|Bacilli	91061|Bacilli	G	PTS system fructose IIA component	-	-	-	ko:K02744	ko00052,ko02060,map00052,map02060	M00277,M00287	R08366,R08367	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.4,4.A.6.1.5	-	-	EIIA-man
XH3_k127_2525017_3	243164.DET0379	6.28e-38	147.0	COG0046@1|root,COG0046@2|Bacteria,2G5Z1@200795|Chloroflexi,34CNB@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
XH3_k127_2595524_0	247490.KSU1_C1111	2.883e-89	304.0	COG2805@1|root,COG2805@2|Bacteria,2IXRP@203682|Planctomycetes	203682|Planctomycetes	NU	COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
XH3_k127_2595524_1	443144.GM21_2665	3.408e-51	201.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,43UJ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
XH3_k127_2631468_0	215803.DB30_7610	6.951e-78	287.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
XH3_k127_2649059_1	760568.Desku_3094	8.683e-73	253.0	COG1773@1|root,COG1853@1|root,COG1773@2|Bacteria,COG1853@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,266U0@186807|Peptococcaceae	186801|Clostridia	C	Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubredoxin
XH3_k127_2649059_0	580340.Tlie_0225	1.202e-102	344.0	COG0426@1|root,COG0426@2|Bacteria,3T9ZQ@508458|Synergistetes	508458|Synergistetes	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
XH3_k127_2682288_0	926549.KI421517_gene923	3.207e-55	196.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,47KVG@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
XH3_k127_2682288_1	378806.STAUR_5642	0.0001904	53.0	COG2372@1|root,COG2372@2|Bacteria,1QSPC@1224|Proteobacteria,433ZQ@68525|delta/epsilon subdivisions,2X4A7@28221|Deltaproteobacteria,2YYKU@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
XH3_k127_2699166_0	864069.MicloDRAFT_00010680	1.193e-106	359.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TUQT@28211|Alphaproteobacteria,1JRXN@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM transposase mutator type	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
XH3_k127_2699166_1	1096756.ATKN01000001_gene2064	0.0009772	47.0	COG3620@1|root,COG3620@2|Bacteria,2I7GD@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_2725692_1	1131269.AQVV01000008_gene911	8.609e-20	94.0	COG4769@1|root,COG4769@2|Bacteria	2|Bacteria	S	Heptaprenyl diphosphate synthase component I	hepS	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
XH3_k127_2725692_2	1150474.JQJI01000012_gene473	8.009e-14	76.0	COG5341@1|root,COG5341@2|Bacteria	2|Bacteria	S	NusG domain II	ynhH	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	NusG_II
XH3_k127_2725692_0	643648.Slip_0096	1.101e-34	140.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,42KAZ@68298|Syntrophomonadaceae	186801|Clostridia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
XH3_k127_2774927_4	644966.Tmar_1093	1.134e-27	119.0	COG1199@1|root,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,25C6H@186801|Clostridia	186801|Clostridia	L	helicase involved in DNA repair and perhaps also replication	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T,RadC,ResIII
XH3_k127_2774927_5	247490.KSU1_B0637	2.632e-27	115.0	2E5IJ@1|root,3309Y@2|Bacteria,2J0P5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_2774927_6	1121438.JNJA01000014_gene466	1.228e-22	104.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria,2MCUY@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
XH3_k127_2774927_2	635013.TherJR_1208	1.577e-59	214.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,261Y2@186807|Peptococcaceae	186801|Clostridia	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
XH3_k127_2774927_0	1379698.RBG1_1C00001G1837	7.041e-186	586.0	COG1260@1|root,COG1260@2|Bacteria,2NNVE@2323|unclassified Bacteria	2|Bacteria	I	Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
XH3_k127_2774927_3	264732.Moth_0042	8.533e-56	202.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,42GBY@68295|Thermoanaerobacterales	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
XH3_k127_2774927_1	1313304.CALK_0992	3.578e-104	353.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
XH3_k127_278517_0	909663.KI867150_gene699	2.571e-87	299.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2MQWK@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PhoH-like protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
XH3_k127_278517_2	1487923.DP73_11975	9.738e-18	89.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,2620D@186807|Peptococcaceae	186801|Clostridia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
XH3_k127_278517_1	97138.C820_00531	1.644e-58	218.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
XH3_k127_2815697_0	1121289.JHVL01000039_gene3130	6.888e-22	111.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,36DDY@31979|Clostridiaceae	186801|Clostridia	O	peptidylprolyl isomerase	prsA2	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
XH3_k127_2815697_1	1219084.AP014508_gene1979	6.43e-21	99.0	COG0170@1|root,COG0344@1|root,COG0170@2|Bacteria,COG0344@2|Bacteria,2GE9C@200918|Thermotogae	200918|Thermotogae	I	Glycerol-3-phosphate acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	G3P_acyltransf
XH3_k127_2889296_4	374847.Kcr_1258	1.04e-45	170.0	COG1363@1|root,arCOG01518@2157|Archaea	2157|Archaea	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
XH3_k127_2889296_2	237368.SCABRO_00279	5.555e-87	302.0	COG1459@1|root,COG1459@2|Bacteria,2IYHA@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
XH3_k127_2889296_0	1536773.R70331_29020	1.732e-131	437.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,26RJM@186822|Paenibacillaceae	91061|Bacilli	NU	type II secretion system protein	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
XH3_k127_2889296_1	673860.AciM339_1223	3.416e-98	335.0	COG0847@1|root,arCOG06460@2157|Archaea,2XZQV@28890|Euryarchaeota	28890|Euryarchaeota	L	P-loop Domain of unknown function (DUF2791)	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	DUF2791
XH3_k127_2889296_3	673860.AciM339_1222	2.967e-52	197.0	COG0847@1|root,arCOG06460@2157|Archaea	2157|Archaea	L	P-loop Domain of unknown function (DUF2791)	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	DUF2791
XH3_k127_2911958_0	909663.KI867150_gene2010	1.057e-70	255.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,42S30@68525|delta/epsilon subdivisions,2WQ5S@28221|Deltaproteobacteria,2MRTS@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
XH3_k127_2917543_0	1379698.RBG1_1C00001G0659	0.0	1181.0	COG0178@1|root,COG0178@2|Bacteria,2NNT3@2323|unclassified Bacteria	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
XH3_k127_2917543_1	909663.KI867150_gene2628	3.232e-274	865.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MR70@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
XH3_k127_2917543_4	1089550.ATTH01000001_gene1105	1.289e-14	79.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1FK4B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
XH3_k127_2917543_2	243231.GSU1138	1.688e-80	278.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
XH3_k127_2917543_3	648996.Theam_1207	5.388e-36	138.0	COG1418@1|root,COG1418@2|Bacteria,2G3QR@200783|Aquificae	200783|Aquificae	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
XH3_k127_2919284_0	269798.CHU_2715	1.976e-29	135.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
XH3_k127_2921477_1	1094980.Mpsy_2165	1.078e-21	95.0	COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,2N9WB@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
XH3_k127_2921477_0	768710.DesyoDRAFT_0996	5.572e-59	220.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,2607U@186807|Peptococcaceae	186801|Clostridia	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
XH3_k127_2921477_2	1122176.KB903543_gene542	0.0008363	50.0	2EBBZ@1|root,335CQ@2|Bacteria,4NXF2@976|Bacteroidetes,1IZYF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4957
XH3_k127_2948902_1	1121472.AQWN01000002_gene2329	2.422e-80	279.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
XH3_k127_2948902_2	1379698.RBG1_1C00001G1829	1.001e-26	109.0	COG0333@1|root,COG0333@2|Bacteria,2NQ1M@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal L32p protein family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
XH3_k127_2948902_0	555088.DealDRAFT_2903	1.558e-87	302.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,42K30@68298|Syntrophomonadaceae	186801|Clostridia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
XH3_k127_2969612_0	319225.Plut_0127	6.335e-175	557.0	COG1003@1|root,COG1003@2|Bacteria,1FDEN@1090|Chlorobi	1090|Chlorobi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
XH3_k127_2969612_2	1379698.RBG1_1C00001G0125	4.882e-14	80.0	2EGJW@1|root,3110Q@2|Bacteria,2NS2A@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_2969612_1	1379698.RBG1_1C00001G0122	3.135e-97	322.0	COG1070@1|root,COG1070@2|Bacteria,2NP2A@2323|unclassified Bacteria	2|Bacteria	G	MutL protein	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N,MutL
XH3_k127_3000339_0	264201.pc0086	1.475e-36	158.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,2JFR7@204428|Chlamydiae	204428|Chlamydiae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
XH3_k127_301414_0	244582.JQAK01000001_gene811	6.774e-23	101.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,47FK1@766|Rickettsiales	766|Rickettsiales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
XH3_k127_301414_1	996637.SGM_3403	3.465e-07	64.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
XH3_k127_3039985_1	479434.Sthe_0131	2.419e-185	601.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi,27XU1@189775|Thermomicrobia	189775|Thermomicrobia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
XH3_k127_3039985_0	1121468.AUBR01000035_gene1394	2.143e-201	640.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
XH3_k127_3073840_0	535289.Dtpsy_2139	5.468e-106	349.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,2VK65@28216|Betaproteobacteria,4AD7R@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM arsenite-activated ATPase ArsA	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase,CbiA
XH3_k127_3073840_3	264732.Moth_0829	9.381e-07	53.0	COG2331@1|root,COG2331@2|Bacteria,1VKRT@1239|Firmicutes,24VXJ@186801|Clostridia	186801|Clostridia	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
XH3_k127_3073840_2	344747.PM8797T_13797	7.066e-29	128.0	2F4XF@1|root,33XJG@2|Bacteria,2J2ZQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_3073840_1	344747.PM8797T_13802	2.965e-29	119.0	COG0577@1|root,COG0577@2|Bacteria,2J25K@203682|Planctomycetes	203682|Planctomycetes	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
XH3_k127_309853_0	562970.Btus_2297	5.355e-86	303.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,277ZP@186823|Alicyclobacillaceae	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
XH3_k127_311968_3	483218.BACPEC_00347	1.452e-10	61.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,269C0@186813|unclassified Clostridiales	186801|Clostridia	J	Ribosomal L27 protein	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
XH3_k127_311968_1	909663.KI867151_gene3156	6.313e-58	208.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WNMC@28221|Deltaproteobacteria,2MQPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
XH3_k127_311968_0	555088.DealDRAFT_2776	1.435e-116	381.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,42K12@68298|Syntrophomonadaceae	186801|Clostridia	C	TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	-	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
XH3_k127_311968_2	1321778.HMPREF1982_00321	3.196e-28	117.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,268VS@186813|unclassified Clostridiales	186801|Clostridia	C	Fumarase C-terminus	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
XH3_k127_313064_5	335543.Sfum_1996	2.428e-45	174.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
XH3_k127_313064_0	632518.Calow_0539	1.096e-119	392.0	COG1924@1|root,COG1924@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,42FXK@68295|Thermoanaerobacterales	186801|Clostridia	I	PFAM ATPase, BadF BadG BcrA BcrD type	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
XH3_k127_313064_3	1121428.DESHY_60158___1	6.024e-68	244.0	COG3581@1|root,COG3581@2|Bacteria,1TPPP@1239|Firmicutes,249C8@186801|Clostridia,25ZYH@186807|Peptococcaceae	186801|Clostridia	I	PFAM CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2229
XH3_k127_313064_4	1121468.AUBR01000014_gene2200	2.012e-54	202.0	COG3580@1|root,COG3580@2|Bacteria,1TR03@1239|Firmicutes,24987@186801|Clostridia,42FG0@68295|Thermoanaerobacterales	186801|Clostridia	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2229
XH3_k127_313064_2	1121468.AUBR01000020_gene2866	2.667e-91	306.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,42EVD@68295|Thermoanaerobacterales	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
XH3_k127_313064_6	1121422.AUMW01000026_gene383	6.976e-33	130.0	COG3383@1|root,COG3383@2|Bacteria,1VAVK@1239|Firmicutes,24MYJ@186801|Clostridia,265MS@186807|Peptococcaceae	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4
XH3_k127_313064_1	1121428.DESHY_110102___1	2.934e-110	366.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,263DR@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
XH3_k127_3160015_2	309801.trd_1965	4.75e-23	105.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi,27XU5@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
XH3_k127_3160015_0	459349.CLOAM1245	4.664e-146	473.0	COG0436@1|root,COG0436@2|Bacteria,2NP0E@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS10450	Aminotran_1_2
XH3_k127_3160015_1	635013.TherJR_1392	1.59e-75	269.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,260B8@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the peptidase M16 family	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
XH3_k127_3170436_0	2055.JNXA01000002_gene2288	5.659e-06	58.0	COG2350@1|root,COG2350@2|Bacteria,2HKSA@201174|Actinobacteria,4GFMM@85026|Gordoniaceae	201174|Actinobacteria	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3,UPF0158
XH3_k127_3173563_0	880073.Calab_2101	3.715e-12	79.0	COG1361@1|root,COG2911@1|root,COG4935@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG4935@2|Bacteria,2NQI0@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
XH3_k127_318420_0	941824.TCEL_00499	8.564e-126	413.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,36E27@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
XH3_k127_318420_1	1449126.JQKL01000002_gene1569	8.348e-91	314.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,26A52@186813|unclassified Clostridiales	186801|Clostridia	C	Acetokinase family	buk	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
XH3_k127_318420_6	713586.KB900536_gene2396	3.78e-11	73.0	COG2227@1|root,COG2227@2|Bacteria,1R0J0@1224|Proteobacteria	1224|Proteobacteria	H	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
XH3_k127_318420_5	1453498.LG45_03300	1.562e-15	88.0	COG0400@1|root,COG0400@2|Bacteria,4NF4I@976|Bacteroidetes,1HXVK@117743|Flavobacteriia,2NTH7@237|Flavobacterium	976|Bacteroidetes	S	phospholipase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
XH3_k127_318420_8	3712.Bo6g051340.1	0.0003227	52.0	2CBEU@1|root,2QQQU@2759|Eukaryota,37SIM@33090|Viridiplantae,3GB6Q@35493|Streptophyta,3HS1M@3699|Brassicales	35493|Streptophyta	-	-	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009507,GO:0009509,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009575,GO:0009579,GO:0009611,GO:0009628,GO:0009642,GO:0009644,GO:0009765,GO:0009941,GO:0009987,GO:0010206,GO:0010207,GO:0015979,GO:0016020,GO:0016043,GO:0019538,GO:0019684,GO:0019898,GO:0022607,GO:0030091,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0034622,GO:0035448,GO:0042170,GO:0042651,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0055035,GO:0065003,GO:0071704,GO:0071840,GO:1901564	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_318420_4	1040989.AWZU01000011_gene4089	1.696e-23	105.0	COG0537@1|root,COG0537@2|Bacteria,1RKXY@1224|Proteobacteria,2UA3J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
XH3_k127_318420_2	1121430.JMLG01000026_gene10	2.998e-55	199.0	COG1751@1|root,COG1751@2|Bacteria,1V1CN@1239|Firmicutes,24G0M@186801|Clostridia,261NK@186807|Peptococcaceae	186801|Clostridia	S	PFAM Pyruvate kinase, alpha beta domain	-	-	-	ko:K09126	-	-	-	-	ko00000	-	-	-	PK_C
XH3_k127_318420_7	330779.Saci_1120	1.924e-10	68.0	COG1545@1|root,arCOG01283@2157|Archaea,2XQEP@28889|Crenarchaeota	28889|Crenarchaeota	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
XH3_k127_318420_3	644282.Deba_1534	4.888e-41	154.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42N6X@68525|delta/epsilon subdivisions,2WJIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
XH3_k127_3186104_0	1499967.BAYZ01000041_gene2336	3.829e-73	254.0	COG1811@1|root,COG1811@2|Bacteria,2NPEK@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF554)	ydfK	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
XH3_k127_3186104_2	756272.Plabr_0919	5.366e-32	143.0	COG1409@1|root,COG1409@2|Bacteria,2J2TN@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
XH3_k127_3186104_3	616991.JPOO01000001_gene4270	2.097e-10	74.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HZHJ@117743|Flavobacteriia,23GZ2@178469|Arenibacter	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
XH3_k127_3186104_1	331678.Cphamn1_1908	1.649e-32	131.0	2DNS7@1|root,32YWC@2|Bacteria	2|Bacteria	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
XH3_k127_3194417_2	867903.ThesuDRAFT_01678	1.573e-34	135.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WCFH@538999|Clostridiales incertae sedis	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
XH3_k127_3194417_0	497964.CfE428DRAFT_2622	8.099e-117	383.0	COG0152@1|root,COG0152@2|Bacteria,46SIP@74201|Verrucomicrobia	74201|Verrucomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
XH3_k127_3194417_1	195522.BD01_1876	5.919e-59	211.0	COG0778@1|root,arCOG00288@2157|Archaea,2XXW2@28890|Euryarchaeota,242IJ@183968|Thermococci	183968|Thermococci	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
XH3_k127_3194417_3	1121405.dsmv_3672	9.932e-32	126.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MIPF@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
XH3_k127_3207514_0	439235.Dalk_2302	9.588e-49	198.0	COG4870@1|root,COG4870@2|Bacteria,1NC9B@1224|Proteobacteria	1224|Proteobacteria	O	PFAM Peptidase C1A, papain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
XH3_k127_3264741_0	518766.Rmar_1363	1.467e-223	709.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
XH3_k127_3264741_1	991905.SL003B_1400	2.452e-06	55.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2U9HZ@28211|Alphaproteobacteria,4BR2Y@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Phosphatidylethanolamine-binding protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
XH3_k127_3273465_0	1537917.JU82_07535	4.256e-184	593.0	COG0028@1|root,COG0028@2|Bacteria,1MYUS@1224|Proteobacteria,42QE8@68525|delta/epsilon subdivisions,2YNKA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
XH3_k127_3273465_1	1536773.R70331_28765	8.792e-135	436.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,271Y5@186822|Paenibacillaceae	91061|Bacilli	M	Dolichol monophosphate mannose synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH3_k127_3273465_2	671065.MetMK1DRAFT_00025330	8.105e-15	75.0	COG0365@1|root,arCOG01529@2157|Archaea,2XPY4@28889|Crenarchaeota	28889|Crenarchaeota	I	synthetase	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0015977,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0043427,GO:0043955,GO:0071704	6.2.1.36	ko:K15018	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00375	R09286	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
XH3_k127_327393_1	1499689.CCNN01000007_gene862	1.296e-30	133.0	COG0454@1|root,COG0456@2|Bacteria,1VWSH@1239|Firmicutes,24FX6@186801|Clostridia,36IE7@31979|Clostridiaceae	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
XH3_k127_327393_0	1121456.ATVA01000011_gene1867	1.129e-64	228.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,42N6F@68525|delta/epsilon subdivisions,2WKX7@28221|Deltaproteobacteria,2M8S4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM 2-nitropropane dioxygenase NPD	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
XH3_k127_3284676_1	1379698.RBG1_1C00001G1358	1.388e-10	70.0	COG0810@1|root,COG0810@2|Bacteria,2NQ1D@2323|unclassified Bacteria	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
XH3_k127_3284676_0	1484157.PSNIH2_02360	8.521e-63	227.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,3VXI5@53335|Pantoea	1236|Gammaproteobacteria	S	MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	iAF1260.b2781,iBWG_1329.BWG_2516,iE2348C_1286.E2348C_3048,iEC55989_1330.EC55989_3056,iECDH10B_1368.ECDH10B_2948,iECDH1ME8569_1439.ECDH1ME8569_2691,iECH74115_1262.ECH74115_4041,iECIAI1_1343.ECIAI1_2889,iECO103_1326.ECO103_3324,iECO111_1330.ECO111_3505,iECO26_1355.ECO26_3851,iECOK1_1307.ECOK1_3155,iECP_1309.ECP_2762,iECSE_1348.ECSE_3039,iECSP_1301.ECSP_3733,iECW_1372.ECW_m2990,iECs_1301.ECs3641,iEKO11_1354.EKO11_0987,iEcDH1_1363.EcDH1_0907,iEcE24377_1341.EcE24377A_3085,iEcHS_1320.EcHS_A2925,iEcolC_1368.EcolC_0931,iG2583_1286.G2583_3433,iJO1366.b2781,iJR904.b2781,iSBO_1134.SBO_2662,iSSON_1240.SSON_2938,iSbBS512_1146.SbBS512_E3092,iUMN146_1321.UM146_02665,iUMNK88_1353.UMNK88_3464,iUTI89_1310.UTI89_C3150,iWFL_1372.ECW_m2990,iY75_1357.Y75_RS14470,iZ_1308.Z4096	MazG
XH3_k127_3364724_0	941824.TCEL_01175	1.862e-80	273.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,36EK7@31979|Clostridiaceae	186801|Clostridia	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
XH3_k127_3364724_1	204669.Acid345_2237	1.717e-58	205.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
XH3_k127_3370821_1	313612.L8106_02282	4.881e-44	175.0	COG1520@1|root,COG2931@1|root,COG4886@1|root,COG5276@1|root,COG5373@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4886@2|Bacteria,COG5276@2|Bacteria,COG5373@2|Bacteria,1G1I0@1117|Cyanobacteria,1H84J@1150|Oscillatoriales	1117|Cyanobacteria	Q	RTX toxins and related Ca2 binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,Peptidase_M10_C
XH3_k127_3370821_0	246194.CHY_2267	3.201e-86	293.0	COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,248K9@186801|Clostridia,42F1Z@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
XH3_k127_3425118_2	518766.Rmar_1259	2.815e-15	79.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1FJJD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	MerR HTH family regulatory protein	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
XH3_k127_3425118_0	1121423.JONT01000014_gene1244	1.261e-70	251.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,260KV@186807|Peptococcaceae	186801|Clostridia	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
XH3_k127_3425118_1	1303518.CCALI_00658	7.483e-36	144.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
XH3_k127_3439300_1	944480.ATUV01000001_gene953	7.789e-63	224.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2M703@213113|Desulfurellales	28221|Deltaproteobacteria	E	Dihydrodipicolinate reductase, C-terminus	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
XH3_k127_3439300_0	429009.Adeg_0351	2.098e-84	289.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,42FSY@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
XH3_k127_3439300_2	1121451.DESAM_22187	4.858e-34	134.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2M88M@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
XH3_k127_3484834_1	1125863.JAFN01000001_gene2044	9.321e-125	409.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
XH3_k127_3484834_0	1121405.dsmv_2869	4.09e-197	636.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
XH3_k127_3484834_2	655815.ZPR_3317	0.0004734	47.0	COG0627@1|root,COG0627@2|Bacteria,4NE7D@976|Bacteroidetes,1I2FI@117743|Flavobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
XH3_k127_3503406_1	404589.Anae109_2060	2.096e-49	190.0	COG0823@1|root,COG3266@1|root,COG4775@1|root,COG0823@2|Bacteria,COG3266@2|Bacteria,COG4775@2|Bacteria,1R8QH@1224|Proteobacteria,42T02@68525|delta/epsilon subdivisions,2WPNU@28221|Deltaproteobacteria,2YUP3@29|Myxococcales	28221|Deltaproteobacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
XH3_k127_3503406_0	1121430.JMLG01000001_gene2403	8.218e-82	286.0	COG0585@1|root,COG0585@2|Bacteria,1TXVC@1239|Firmicutes,24DVS@186801|Clostridia	186801|Clostridia	J	PFAM tRNA pseudouridine synthase D TruD	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
XH3_k127_3503406_2	502025.Hoch_3449	2.923e-19	90.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,42U2Q@68525|delta/epsilon subdivisions,2WQK9@28221|Deltaproteobacteria,2YW3Q@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
XH3_k127_3519548_2	484770.UFO1_1015	1.169e-08	62.0	COG0848@1|root,COG0848@2|Bacteria,1V6MA@1239|Firmicutes,4H4ZF@909932|Negativicutes	909932|Negativicutes	U	protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
XH3_k127_3519548_3	1072685.IX83_04800	0.0002093	49.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2VSVW@28216|Betaproteobacteria,3T44N@506|Alcaligenaceae	28216|Betaproteobacteria	U	Biopolymer transport protein	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
XH3_k127_3519548_1	596323.HMPREF0554_1505	4.603e-18	93.0	COG0811@1|root,COG0811@2|Bacteria,379FS@32066|Fusobacteria	32066|Fusobacteria	U	Transporter, MotA TolQ ExbB proton channel family protein	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
XH3_k127_3519548_0	1499967.BAYZ01000055_gene4846	1.712e-23	112.0	COG0457@1|root,COG4105@1|root,COG0457@2|Bacteria,COG4105@2|Bacteria,2NRIW@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	bamD	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	TPR_16,TPR_6,YfiO
XH3_k127_3522447_0	1121472.AQWN01000007_gene1144	1.961e-53	194.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
XH3_k127_3536708_0	290340.AAur_3601	3.707e-06	57.0	COG2020@1|root,COG2020@2|Bacteria,2IN0C@201174|Actinobacteria	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
XH3_k127_3545996_0	880073.Calab_3531	2.61e-66	239.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
XH3_k127_3545996_1	1487923.DP73_17660	1.007e-52	195.0	28Q1U@1|root,2ZCK2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
XH3_k127_3545996_2	1123405.AUMM01000060_gene1863	1.449e-05	54.0	2EWAE@1|root,33PP5@2|Bacteria,1VTAY@1239|Firmicutes,4HTB5@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
XH3_k127_355017_2	1121889.AUDM01000010_gene584	3.285e-20	97.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes,1I0CF@117743|Flavobacteriia,2P0BI@237|Flavobacterium	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
XH3_k127_355017_3	1280682.AUKA01000010_gene164	8.833e-14	80.0	COG1434@1|root,COG2020@1|root,COG1434@2|Bacteria,COG2020@2|Bacteria,1V3IZ@1239|Firmicutes,24FW3@186801|Clostridia,4C1NS@830|Butyrivibrio	186801|Clostridia	O	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF218,PEMT
XH3_k127_355017_0	435591.BDI_1705	6.515e-82	287.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,2FM3E@200643|Bacteroidia,22VV2@171551|Porphyromonadaceae	976|Bacteroidetes	EJ	L-asparaginase, type I	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
XH3_k127_355017_1	1265505.ATUG01000003_gene307	3.493e-28	118.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,42QVG@68525|delta/epsilon subdivisions,2WNKA@28221|Deltaproteobacteria,2MJNQ@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
XH3_k127_3550641_1	1449050.JNLE01000005_gene5207	0.0002737	51.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
XH3_k127_3550641_0	459349.CLOAM0099	1.31e-87	319.0	COG2234@1|root,COG2234@2|Bacteria,2NQ2F@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M28	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
XH3_k127_3556794_3	269797.Mbar_A3737	1.047e-54	209.0	COG1520@1|root,COG3291@1|root,arCOG03991@1|root,arCOG02482@2157|Archaea,arCOG02508@2157|Archaea,arCOG03991@2157|Archaea,2XUI1@28890|Euryarchaeota,2NBKW@224756|Methanomicrobia	28890|Euryarchaeota	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	PKD
XH3_k127_3556794_2	56110.Oscil6304_5971	2.679e-61	220.0	COG1043@1|root,COG1043@2|Bacteria,1G1V3@1117|Cyanobacteria,1H812@1150|Oscillatoriales	1117|Cyanobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iJN678.lpxA	Acetyltransf_11,Hexapep
XH3_k127_3556794_6	1123371.ATXH01000009_gene1083	6.044e-32	130.0	COG0764@1|root,COG0764@2|Bacteria,2GHDE@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
XH3_k127_3556794_5	2903.EOD41889	2.934e-32	137.0	COG0774@1|root,2QT9Y@2759|Eukaryota	2759|Eukaryota	M	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006040,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008759,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:2001289	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
XH3_k127_3556794_4	1125863.JAFN01000001_gene3410	1.433e-49	184.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
XH3_k127_3556794_7	1121904.ARBP01000009_gene4324	3.604e-09	68.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,47PD1@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane protein (OmpH-like)	skp	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
XH3_k127_3556794_1	243231.GSU2568	5.648e-80	281.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,43TX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	SMART Elongator protein 3 MiaB NifB	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
XH3_k127_3556794_0	1379698.RBG1_1C00001G1225	7.055e-122	403.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4,2.7.11.1	ko:K02945,ko:K03527,ko:K12132	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011	-	-	-	S1
XH3_k127_3562700_2	909663.KI867150_gene2857	2.566e-25	109.0	COG1120@1|root,COG1120@2|Bacteria,1QUJW@1224|Proteobacteria,43053@68525|delta/epsilon subdivisions,2WP2F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HP	ABC transporter	-	-	-	ko:K09820	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
XH3_k127_3562700_1	760568.Desku_2173	5.864e-75	260.0	COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,248FP@186801|Clostridia,265NU@186807|Peptococcaceae	186801|Clostridia	P	ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
XH3_k127_3562700_0	1125863.JAFN01000001_gene2492	5.725e-141	452.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2WJMT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169	PEPCK_ATP
XH3_k127_3570502_3	224325.AF_1199	3.853e-77	267.0	COG1788@1|root,arCOG01987@2157|Archaea,2XVRA@28890|Euryarchaeota,246WP@183980|Archaeoglobi	183980|Archaeoglobi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
XH3_k127_3570502_2	1210884.HG799462_gene8369	1.764e-86	295.0	COG2057@1|root,COG2057@2|Bacteria	2|Bacteria	I	CoA-transferase activity	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
XH3_k127_3570502_1	273068.TTE0545	4.165e-101	342.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	bcd	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108,1.3.8.1	ko:K00248,ko:K22430	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH3_k127_3570502_0	273068.TTE0545	2.852e-139	454.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	bcd	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108,1.3.8.1	ko:K00248,ko:K22430	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH3_k127_3629981_0	240292.Ava_1901	3.42e-152	492.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,1HJKB@1161|Nostocales	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
XH3_k127_3629981_1	696747.NIES39_C02780	3.75e-33	142.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1HA36@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,TPR_12,TPR_7,TPR_8
XH3_k127_3633639_6	69014.TK1552	2.072e-07	61.0	COG5617@1|root,arCOG07110@2157|Archaea,2Y38Y@28890|Euryarchaeota,24337@183968|Thermococci	183968|Thermococci	S	6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
XH3_k127_3633639_4	177437.HRM2_35820	5.818e-31	125.0	COG3370@1|root,COG3370@2|Bacteria,1N3DX@1224|Proteobacteria,42UA2@68525|delta/epsilon subdivisions,2WQ2I@28221|Deltaproteobacteria,2MKGA@213118|Desulfobacterales	28221|Deltaproteobacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
XH3_k127_3633639_1	765177.Desmu_0066	2.431e-48	181.0	COG0500@1|root,arCOG01773@2157|Archaea,2XQP4@28889|Crenarchaeota	28889|Crenarchaeota	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
XH3_k127_3633639_3	374847.Kcr_0638	1.635e-31	139.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
XH3_k127_3633639_0	1408433.JHXV01000002_gene442	6.859e-115	396.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
XH3_k127_3633639_5	1396141.BATP01000006_gene5462	2.119e-16	94.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K16260	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	FecR,Lectin_C,Polyketide_cyc2,VIT,VWA_2,VWA_3
XH3_k127_3633639_2	515635.Dtur_1285	2.019e-36	154.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
XH3_k127_3633639_7	665571.STHERM_c00960	0.0003507	45.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,2J6UE@203691|Spirochaetes	203691|Spirochaetes	U	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
XH3_k127_3637305_1	459349.CLOAM0061	1.434e-11	78.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	wprA	-	3.1.3.6,3.1.4.16,3.2.1.99	ko:K01119,ko:K06113,ko:K12685,ko:K20276	ko00230,ko00240,ko02024,map00230,map00240,map02024	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Mucin_bdg,Peptidase_M60,Peptidase_S8,SLH
XH3_k127_3637305_0	579137.Metvu_0881	2.173e-54	205.0	COG4870@1|root,arCOG03418@1|root,arCOG04500@1|root,arCOG03418@2157|Archaea,arCOG03607@2157|Archaea,arCOG04500@2157|Archaea	2157|Archaea	O	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,NosD,Peptidase_C1,S_layer_C
XH3_k127_3660014_0	945713.IALB_2907	6.015e-90	328.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
XH3_k127_3660014_1	880073.Calab_0041	1.256e-12	81.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
XH3_k127_3717146_1	1232410.KI421424_gene1590	5.877e-77	269.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43C4K@68525|delta/epsilon subdivisions,2X7F1@28221|Deltaproteobacteria,43TX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains HisKA, HATPase_c	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
XH3_k127_3717146_0	1125863.JAFN01000001_gene1446	9.131e-127	419.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
XH3_k127_3717146_2	589865.DaAHT2_0080	5.126e-73	261.0	COG4591@1|root,COG4591@2|Bacteria,1R0RM@1224|Proteobacteria,43CZW@68525|delta/epsilon subdivisions,2X885@28221|Deltaproteobacteria,2MKW1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
XH3_k127_3726871_3	1045009.AFXQ01000009_gene801	9.283e-06	51.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
XH3_k127_3726871_0	1128421.JAGA01000002_gene1359	1.482e-68	246.0	COG0520@1|root,COG0520@2|Bacteria,2NP4B@2323|unclassified Bacteria	2|Bacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
XH3_k127_3726871_2	1210884.HG799466_gene12831	2.233e-12	80.0	COG1520@1|root,COG1520@2|Bacteria,2IYTM@203682|Planctomycetes	203682|Planctomycetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_3726871_1	118161.KB235922_gene1026	1.718e-12	77.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1G0YS@1117|Cyanobacteria	1117|Cyanobacteria	O	O-linked N-acetylglucosamine transferase SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Sulfotransfer_2,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
XH3_k127_3754479_1	880073.Calab_1430	8.394e-44	166.0	COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
XH3_k127_3754479_0	903818.KI912268_gene1464	4.95e-75	268.0	COG0642@1|root,COG2205@2|Bacteria	903818.KI912268_gene1464|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_3764335_5	41431.PCC8801_2357	1.617e-19	91.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	2TM,His_kinase
XH3_k127_3764335_6	1047013.AQSP01000109_gene2440	8.333e-19	93.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
XH3_k127_3764335_1	335543.Sfum_0266	3.205e-95	320.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42PQM@68525|delta/epsilon subdivisions,2WJIF@28221|Deltaproteobacteria,2MRCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	HTH_20,Methyltransf_31
XH3_k127_3764335_4	234267.Acid_7199	1.076e-20	105.0	COG0793@1|root,COG0793@2|Bacteria,3Y8S0@57723|Acidobacteria	57723|Acidobacteria	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
XH3_k127_3764335_0	243231.GSU1088	1.081e-117	399.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,43S4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
XH3_k127_3764335_7	1501391.LG35_05795	4.569e-18	89.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,2FTV5@200643|Bacteroidia,22UIU@171550|Rikenellaceae	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
XH3_k127_3764335_2	1379698.RBG1_1C00001G0748	1.516e-87	313.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
XH3_k127_3764335_3	436114.SYO3AOP1_0687	2.692e-81	282.0	COG0136@1|root,COG0136@2|Bacteria,2G3QW@200783|Aquificae	200783|Aquificae	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
XH3_k127_3764335_8	1229780.BN381_80238	7.233e-05	49.0	COG4122@1|root,COG4122@2|Bacteria,2GJCJ@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
XH3_k127_377480_1	1047013.AQSP01000092_gene323	2.79e-106	349.0	COG0798@1|root,COG0798@2|Bacteria,2NNWJ@2323|unclassified Bacteria	2|Bacteria	P	Sodium Bile acid symporter family	arsB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
XH3_k127_377480_2	344747.PM8797T_13807	5.023e-81	275.0	COG1136@1|root,COG1136@2|Bacteria,2J1YS@203682|Planctomycetes	203682|Planctomycetes	V	COG1136 ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
XH3_k127_377480_0	344747.PM8797T_13802	2.658e-113	376.0	COG0577@1|root,COG0577@2|Bacteria,2J25K@203682|Planctomycetes	203682|Planctomycetes	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
XH3_k127_3792460_1	314278.NB231_12444	6.498e-09	63.0	COG4916@1|root,COG4916@2|Bacteria,1R81D@1224|Proteobacteria,1S7RT@1236|Gammaproteobacteria,1WYW5@135613|Chromatiales	135613|Chromatiales	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
XH3_k127_3792460_2	439235.Dalk_1948	3.943e-05	55.0	COG1357@1|root,COG1357@2|Bacteria,1NGZN@1224|Proteobacteria,436D1@68525|delta/epsilon subdivisions,2WV4W@28221|Deltaproteobacteria,2MP4M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
XH3_k127_3792460_0	1168067.JAGP01000001_gene1217	2.416e-10	72.0	arCOG06889@1|root,31151@2|Bacteria,1NBZJ@1224|Proteobacteria,1T06M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
XH3_k127_3799085_2	1394176.AWUO01000006_gene576	4.064e-12	72.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ24@85004|Bifidobacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
XH3_k127_3799085_0	755732.Fluta_1682	7.44e-49	200.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PI0A@976|Bacteroidetes,1IMVQ@117743|Flavobacteriia,2PBY2@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
XH3_k127_3799085_1	673860.AciM339_0730	1.417e-19	105.0	COG4934@1|root,arCOG05978@1|root,arCOG03669@2157|Archaea,arCOG05978@2157|Archaea,2Y7X2@28890|Euryarchaeota,3F38G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ,fn3
XH3_k127_3799085_3	309799.DICTH_1470	0.0003365	45.0	COG3350@1|root,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,YHS
XH3_k127_3861633_2	696281.Desru_2381	2.476e-37	143.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,260V0@186807|Peptococcaceae	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
XH3_k127_3861633_0	521045.Kole_0512	3.868e-96	331.0	COG0770@1|root,COG0770@2|Bacteria,2GCZ1@200918|Thermotogae	200918|Thermotogae	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	-	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
XH3_k127_3861633_1	273068.TTE1336	2.842e-74	254.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,42EY5@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Conserved carboxylase region	pycB	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
XH3_k127_3876875_2	44056.XP_009042312.1	2.21e-14	79.0	COG0204@1|root,KOG2848@2759|Eukaryota	2759|Eukaryota	I	1-acylglycerol-3-phosphate O-acyltransferase activity	-	GO:0000003,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0007275,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009507,GO:0009526,GO:0009536,GO:0009790,GO:0009791,GO:0009793,GO:0009941,GO:0009987,GO:0010154,GO:0019637,GO:0022414,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0061458,GO:0071704,GO:0090407,GO:1901576	2.3.1.51	ko:K00655,ko:K13509	ko00561,ko00564,ko01100,ko01110,ko04072,ko04975,map00561,map00564,map01100,map01110,map04072,map04975	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
XH3_k127_3876875_1	572479.Hprae_0784	6.437e-58	212.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3WA6D@53433|Halanaerobiales	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
XH3_k127_3876875_0	1379698.RBG1_1C00001G1225	5.807e-126	418.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4,2.7.11.1	ko:K02945,ko:K03527,ko:K12132	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011	-	-	-	S1
XH3_k127_3921086_2	234267.Acid_0315	1.291e-09	61.0	COG1514@1|root,COG1514@2|Bacteria,3Y5S7@57723|Acidobacteria	57723|Acidobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
XH3_k127_3921086_1	331869.BAL199_09008	4.214e-10	66.0	COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,2UC8X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	MA20_06475	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
XH3_k127_3921086_0	521045.Kole_0309	1.873e-117	385.0	COG0330@1|root,COG0330@2|Bacteria,2GC8F@200918|Thermotogae	200918|Thermotogae	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
XH3_k127_3921905_1	953739.SVEN_7222	3.458e-49	196.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria	201174|Actinobacteria	M	PFAM peptidase M6, immune inhibitor A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
XH3_k127_3921905_0	1123371.ATXH01000012_gene1431	5.51e-117	385.0	COG1158@1|root,COG1158@2|Bacteria,2GGXS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
XH3_k127_3925724_6	880073.Calab_1427	2.992e-16	79.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,2NNXH@2323|unclassified Bacteria	2|Bacteria	C	Iron hydrogenase small subunit	-	-	1.12.1.3,1.17.1.9,1.6.5.3	ko:K00123,ko:K00336,ko:K18332	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_6,Fer4_9,NADH-G_4Fe-4S_3,Pyr_redox_2
XH3_k127_3925724_5	1191523.MROS_2484	1.742e-25	113.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
XH3_k127_3925724_0	880073.Calab_1426	9.541e-231	732.0	COG4191@1|root,COG4624@1|root,COG4191@2|Bacteria,COG4624@2|Bacteria,2NP4X@2323|unclassified Bacteria	2|Bacteria	C	Putative Fe-S cluster	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,HAMP,HATPase_c,HTH_8,HisKA,PAS_9,Sigma54_activat
XH3_k127_3925724_1	880073.Calab_1424	1.707e-122	404.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_9
XH3_k127_3925724_4	903818.KI912268_gene1460	4.253e-38	145.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.13.3	ko:K02282,ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044	-	-	-	AAA_31,CheW,GGDEF,H-kinase_dim,HATPase_c,Hpt,Response_reg
XH3_k127_3925724_3	903818.KI912268_gene1461	1.794e-52	196.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	hoxF	-	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
XH3_k127_3925724_2	903818.KI912268_gene1462	5.853e-67	235.0	COG1894@1|root,COG1894@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	hoxF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
XH3_k127_3942387_1	1232453.BAIF02000135_gene1598	2.698e-83	290.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
XH3_k127_3942387_2	335541.Swol_1195	1.836e-42	174.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia,42JYB@68298|Syntrophomonadaceae	186801|Clostridia	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
XH3_k127_3942387_0	1121430.JMLG01000002_gene1268	1.619e-111	372.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,260MU@186807|Peptococcaceae	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
XH3_k127_3943751_0	459349.CLOAM0617	5.88e-20	102.0	COG2067@1|root,COG2067@2|Bacteria,2NPV7@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
XH3_k127_3943751_1	861299.J421_0153	5.453e-11	76.0	COG4409@1|root,COG4409@2|Bacteria,1ZUI0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_3953891_9	760568.Desku_2340	4.612e-19	102.0	arCOG09742@1|root,2ZBGR@2|Bacteria,1V0RW@1239|Firmicutes,24AYH@186801|Clostridia,263KV@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_3953891_0	481448.Minf_0010	1.868e-164	527.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,37GBP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
XH3_k127_3953891_1	234267.Acid_1371	4.476e-123	405.0	COG0451@1|root,COG0451@2|Bacteria,3Y3T4@57723|Acidobacteria	57723|Acidobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
XH3_k127_3953891_7	926566.Terro_1261	1.567e-26	122.0	COG0673@1|root,COG0673@2|Bacteria,3Y486@57723|Acidobacteria,2JHJI@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
XH3_k127_3953891_4	765420.OSCT_2897	4.71e-63	224.0	COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,375BM@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
XH3_k127_3953891_3	632335.Calkr_0871	2.016e-66	233.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,42EW3@68295|Thermoanaerobacterales	186801|Clostridia	D	TIGRFAM Cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
XH3_k127_3953891_8	1334046.AYTB01000007_gene2978	2.672e-22	107.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,26DPE@186818|Planococcaceae	91061|Bacilli	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0032506,GO:0034097,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
XH3_k127_3953891_5	580340.Tlie_1369	1.043e-40	166.0	COG4942@1|root,COG4942@2|Bacteria,3T9S7@508458|Synergistetes	508458|Synergistetes	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
XH3_k127_3953891_6	518766.Rmar_2254	8.019e-30	132.0	COG2812@1|root,COG2812@2|Bacteria,4PKEA@976|Bacteroidetes,1FJ1I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
XH3_k127_3953891_10	1236902.ANAS01000009_gene2646	6.816e-18	88.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4EJTC@85012|Streptosporangiales	201174|Actinobacteria	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
XH3_k127_3953891_2	1191523.MROS_2409	3.155e-70	273.0	COG4797@1|root,COG4797@2|Bacteria	2|Bacteria	-	-	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
XH3_k127_3957624_0	697303.Thewi_2263	1.691e-232	755.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,42ETP@68295|Thermoanaerobacterales	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
XH3_k127_3957624_1	318996.AXAZ01000026_gene6939	7.888e-32	128.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,3JYT4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
XH3_k127_3961195_1	2423.NA23_0200770	1.825e-41	161.0	COG0665@1|root,COG0665@2|Bacteria,2GC7R@200918|Thermotogae	200918|Thermotogae	E	PFAM FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
XH3_k127_3961195_2	1121422.AUMW01000026_gene386	2.817e-17	86.0	COG1251@1|root,COG1251@2|Bacteria,1VI2I@1239|Firmicutes,24TGP@186801|Clostridia	186801|Clostridia	C	PFAM BFD-like 2Fe-2S -binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
XH3_k127_3961195_0	1379698.RBG1_1C00001G0370	2.45e-105	357.0	COG0616@1|root,COG0616@2|Bacteria,2NNKU@2323|unclassified Bacteria	2|Bacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
XH3_k127_3973741_0	1379698.RBG1_1C00001G0356	9.017e-73	274.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
XH3_k127_3980718_1	338966.Ppro_0588	9.031e-91	317.0	COG1009@1|root,COG1009@2|Bacteria,1QV11@1224|Proteobacteria,43CGR@68525|delta/epsilon subdivisions,2X7RW@28221|Deltaproteobacteria	1224|Proteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
XH3_k127_3980718_7	926569.ANT_06030	1.961e-18	92.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2G67I@200795|Chloroflexi	200795|Chloroflexi	CP	NADH Ubiquinone plastoquinone (complex I)	echA	-	-	ko:K05565,ko:K14086	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,Proton_antipo_M,Proton_antipo_N
XH3_k127_3980718_6	1042877.GQS_07560	4.159e-23	104.0	COG2111@1|root,arCOG03079@2157|Archaea,2XUEC@28890|Euryarchaeota,2440D@183968|Thermococci	183968|Thermococci	P	Domain related to MnhB subunit of Na+/H+ antiporter	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
XH3_k127_3980718_5	391623.TERMP_00860	3.817e-24	109.0	COG1006@1|root,arCOG03072@2157|Archaea,2XYD3@28890|Euryarchaeota,245I5@183968|Thermococci	183968|Thermococci	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
XH3_k127_3980718_0	521045.Kole_0565	6.164e-109	370.0	COG0651@1|root,COG0651@2|Bacteria,2GE49@200918|Thermotogae	200918|Thermotogae	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
XH3_k127_3980718_2	511051.CSE_04040	2.14e-36	143.0	COG1863@1|root,COG1863@2|Bacteria	2|Bacteria	P	multisubunit Na H antiporter MnhE subunit	mrpE	-	-	ko:K05562,ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
XH3_k127_3980718_8	1183377.Py04_1296	7.519e-11	67.0	COG2212@1|root,arCOG03121@2157|Archaea,2XZ7H@28890|Euryarchaeota,244HZ@183968|Thermococci	183968|Thermococci	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
XH3_k127_3980718_3	521045.Kole_0562	5.161e-29	120.0	COG1320@1|root,COG1320@2|Bacteria	2|Bacteria	P	monovalent cation:proton antiporter activity	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
XH3_k127_3980718_4	521045.Kole_0561	6.619e-26	112.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	ko:K12143	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Flavodoxin_5
XH3_k127_3989432_0	517418.Ctha_1905	1.009e-17	89.0	2EE5F@1|root,33800@2|Bacteria,1FFN1@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_403841_3	767817.Desgi_4193	6.253e-09	60.0	COG4640@1|root,COG4640@2|Bacteria,1TQ9M@1239|Firmicutes,24DDM@186801|Clostridia,264D0@186807|Peptococcaceae	186801|Clostridia	S	DUF3160	-	-	-	-	-	-	-	-	-	-	-	-	DUF3160,zinc_ribbon_2
XH3_k127_403841_1	1120973.AQXL01000127_gene2680	9.878e-80	278.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,2782F@186823|Alicyclobacillaceae	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
XH3_k127_403841_0	1479238.JQMZ01000001_gene387	5.432e-82	281.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria,43WPA@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
XH3_k127_403841_2	243231.GSU2923	4.244e-43	163.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
XH3_k127_4067858_0	1379270.AUXF01000006_gene30	6.85e-30	137.0	COG0760@1|root,COG0760@2|Bacteria,1ZTD1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_2
XH3_k127_4101945_7	439481.Aboo_0833	2.609e-24	105.0	COG1546@1|root,arCOG04589@2157|Archaea,2XUK6@28890|Euryarchaeota,3F2QW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Competence-damaged protein	cinA3	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
XH3_k127_4101945_5	880073.Calab_1192	4.355e-28	122.0	COG1267@1|root,COG1267@2|Bacteria,2NPTB@2323|unclassified Bacteria	2|Bacteria	I	Phosphatidylglycerophosphatase A	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0195,iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
XH3_k127_4101945_3	1232410.KI421418_gene2299	1.356e-60	220.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43RZY@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	SecD/SecF GG Motif	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
XH3_k127_4101945_1	1379698.RBG1_1C00001G0345	6.824e-119	404.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
XH3_k127_4101945_2	292564.Cyagr_0903	1.184e-63	226.0	COG0854@1|root,COG0854@2|Bacteria,1G0QW@1117|Cyanobacteria,22S7Q@167375|Cyanobium	1117|Cyanobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
XH3_k127_4101945_10	179408.Osc7112_4697	0.0001582	52.0	COG0500@1|root,COG2226@2|Bacteria,1G5M2@1117|Cyanobacteria,1HDYJ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
XH3_k127_4101945_9	487796.Flav2ADRAFT_1708	4.199e-08	57.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,1I3XI@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
XH3_k127_4101945_4	1379698.RBG1_1C00001G0993	3.177e-42	169.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
XH3_k127_4101945_0	1379698.RBG1_1C00001G0995	2.604e-150	505.0	COG5617@1|root,COG5617@2|Bacteria,2NS5H@2323|unclassified Bacteria	2|Bacteria	E	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
XH3_k127_4101945_6	368407.Memar_0693	1.694e-26	122.0	COG0438@1|root,arCOG01403@2157|Archaea,2XUDX@28890|Euryarchaeota,2NB1C@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
XH3_k127_4101945_8	706587.Desti_3313	1.616e-19	102.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,Kelch_1,Kelch_3,Kelch_4,Kelch_6,REJ
XH3_k127_4101945_11	518766.Rmar_0260	0.000174	54.0	COG4447@1|root,COG4447@2|Bacteria,4P02B@976|Bacteroidetes,1FIYU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
XH3_k127_4145460_1	1047013.AQSP01000100_gene597	6.747e-57	204.0	COG1387@1|root,COG1387@2|Bacteria,2NNNK@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase X family	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
XH3_k127_4145460_3	1117379.BABA_19961	0.0008945	50.0	COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli,1ZAQZ@1386|Bacillus	91061|Bacilli	S	Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
XH3_k127_4145460_2	56780.SYN_00415	1.645e-31	138.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,2MQIX@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
XH3_k127_4145460_0	59374.Fisuc_2153	6.113e-58	218.0	COG0795@1|root,COG0795@2|Bacteria	2|Bacteria	M	lipopolysaccharide-transporting ATPase activity	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
XH3_k127_4233097_0	290397.Adeh_3524	7.764e-91	330.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
XH3_k127_4272808_2	457570.Nther_0354	6.631e-11	72.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta_helix
XH3_k127_4272808_0	591019.Shell_0586	1.156e-40	165.0	COG2248@1|root,arCOG00969@2157|Archaea,2XQEH@28889|Crenarchaeota	28889|Crenarchaeota	S	Belongs to the UPF0282 family	-	-	-	ko:K07022	-	-	-	-	ko00000	-	-	-	Lactamase_B,Lactamase_B_2,Lactamase_B_3
XH3_k127_4272808_1	1121382.JQKG01000056_gene3748	2.278e-31	134.0	COG4589@1|root,COG4589@2|Bacteria,1WIDA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
XH3_k127_432284_0	289376.THEYE_A1018	2.46e-37	145.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
XH3_k127_432284_1	518766.Rmar_1484	0.0008917	49.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Kelch_4
XH3_k127_4348143_0	401526.TcarDRAFT_0959	3.213e-215	703.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H24T@909932|Negativicutes	909932|Negativicutes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
XH3_k127_4348143_2	383372.Rcas_0713	3.56e-32	134.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi,375TA@32061|Chloroflexia	32061|Chloroflexia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
XH3_k127_4348143_1	1379698.RBG1_1C00001G1459	2.992e-120	394.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
XH3_k127_4355354_1	1191523.MROS_0475	1.916e-96	347.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
XH3_k127_4355354_0	880073.Calab_0412	1.774e-141	480.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
XH3_k127_4355354_2	880073.Calab_0412	5.564e-73	259.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
XH3_k127_4360819_8	1380408.AVGH01000035_gene195	3.86e-31	126.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,21WMU@150247|Anoxybacillus	91061|Bacilli	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
XH3_k127_4360819_10	592028.GCWU000321_00946	4.264e-20	93.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4H56M@909932|Negativicutes	909932|Negativicutes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
XH3_k127_4360819_0	880073.Calab_2129	9.832e-98	326.0	COG0090@1|root,COG0090@2|Bacteria,2NNR3@2323|unclassified Bacteria	2|Bacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
XH3_k127_4360819_7	880073.Calab_2130	9.994e-34	132.0	COG0185@1|root,COG0185@2|Bacteria,2NPIV@2323|unclassified Bacteria	2|Bacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
XH3_k127_4360819_14	1121422.AUMW01000023_gene2781	2.957e-13	74.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,2621D@186807|Peptococcaceae	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
XH3_k127_4360819_1	1121861.KB899921_gene2948	1.401e-71	247.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,2JQ8H@204441|Rhodospirillales	204441|Rhodospirillales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
XH3_k127_4360819_3	1379698.RBG1_1C00001G1589	5.051e-54	192.0	COG0197@1|root,COG0197@2|Bacteria,2NPC6@2323|unclassified Bacteria	2|Bacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
XH3_k127_4360819_15	546269.HMPREF0389_00839	4.202e-09	59.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,25RVP@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
XH3_k127_4360819_12	401526.TcarDRAFT_1007	4.201e-18	88.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4H533@909932|Negativicutes	909932|Negativicutes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
XH3_k127_4360819_4	945713.IALB_0922	3.279e-45	168.0	COG0093@1|root,COG0093@2|Bacteria	2|Bacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
XH3_k127_4360819_9	1504822.CCNO01000011_gene134	2.625e-22	99.0	COG0198@1|root,COG0198@2|Bacteria	2|Bacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
XH3_k127_4360819_2	1392489.JPOL01000002_gene1326	9.202e-61	217.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,1HX1E@117743|Flavobacteriia,2XIM7@283735|Leeuwenhoekiella	976|Bacteroidetes	J	ribosomal L5P family C-terminus	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
XH3_k127_4360819_11	247490.KSU1_C1221	5.184e-19	88.0	COG0199@1|root,COG0199@2|Bacteria,2J0QE@203682|Planctomycetes	203682|Planctomycetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
XH3_k127_4360819_5	234267.Acid_5104	2.58e-35	138.0	COG0096@1|root,COG0096@2|Bacteria,3Y4IE@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
XH3_k127_4360819_6	247639.MGP2080_06522	3.199e-34	139.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1J5Q4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
XH3_k127_4360819_13	56780.SYN_02190	1.102e-13	75.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2MQHR@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PP-loop family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
XH3_k127_4406901_0	742817.HMPREF9449_01252	3.922e-33	138.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
XH3_k127_4407235_1	28072.Nos7524_0173	1.033e-08	67.0	COG4775@1|root,COG4775@2|Bacteria,1G389@1117|Cyanobacteria,1HKBR@1161|Nostocales	1117|Cyanobacteria	M	Surface antigen variable number repeat	IAP75	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA,POTRA_2
XH3_k127_4407235_0	1047013.AQSP01000076_gene1478	2.774e-51	184.0	COG1600@1|root,COG1600@2|Bacteria,2NRKC@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_16,Fer4_7
XH3_k127_4416674_1	203275.BFO_0217	6.374e-34	133.0	COG1070@1|root,COG1070@2|Bacteria,4NIJC@976|Bacteroidetes,2FP4C@200643|Bacteroidia,22X3Q@171551|Porphyromonadaceae	976|Bacteroidetes	G	FGGY family of carbohydrate kinases, N-terminal domain	rhaB	GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	2.7.1.5,2.7.1.51	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014,R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
XH3_k127_4416674_0	926569.ANT_24910	5.521e-182	582.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
XH3_k127_4449236_0	1907.SGLAU_29200	1.694e-60	220.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
XH3_k127_4449236_1	1449050.JNLE01000003_gene940	1.398e-51	197.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E82@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
XH3_k127_4485344_2	439235.Dalk_3208	3.266e-05	51.0	2DMZP@1|root,32UMQ@2|Bacteria,1N3K9@1224|Proteobacteria,42UFA@68525|delta/epsilon subdivisions,2WQ9Z@28221|Deltaproteobacteria,2MNTS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
XH3_k127_4485344_3	751944.HALDL1_03215	4.035e-05	56.0	COG5276@1|root,arCOG02565@2157|Archaea,2XV6J@28890|Euryarchaeota,23SNQ@183963|Halobacteria	183963|Halobacteria	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
XH3_k127_4485344_5	1123306.KB904358_gene841	0.0001629	54.0	COG0526@1|root,COG0526@2|Bacteria,1V52A@1239|Firmicutes,4HHDU@91061|Bacilli	91061|Bacilli	CO	thiol-disulfide isomerase and thioredoxins	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
XH3_k127_4485344_4	502025.Hoch_6267	0.000156	51.0	COG1225@1|root,COG3121@1|root,COG5276@1|root,COG1225@2|Bacteria,COG3121@2|Bacteria,COG5276@2|Bacteria,1QKKE@1224|Proteobacteria,435N7@68525|delta/epsilon subdivisions,2X01F@28221|Deltaproteobacteria,2YZSE@29|Myxococcales	28221|Deltaproteobacteria	NOU	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	ASH,AhpC-TSA,LVIVD
XH3_k127_4485344_1	518766.Rmar_1484	6.147e-08	61.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Kelch_4
XH3_k127_4485344_0	688270.Celal_0298	1.573e-29	131.0	COG4124@1|root,COG4124@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cu_amine_oxidN1,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_26,SLH
XH3_k127_4529395_0	1274524.BSONL12_06773	8.563e-71	251.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZB9G@1386|Bacillus	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rlmCD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
XH3_k127_4529395_3	1089550.ATTH01000001_gene1491	1.469e-08	62.0	29GCI@1|root,30SMI@2|Bacteria,4PENN@976|Bacteroidetes,1FJCI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
XH3_k127_4529395_1	596319.STAWA0001_0612	3.319e-13	80.0	2ERYM@1|root,33JHS@2|Bacteria,1VMJJ@1239|Firmicutes	1239|Firmicutes	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
XH3_k127_4529395_2	754477.Q7C_1483	1.157e-09	69.0	COG4916@1|root,COG4916@2|Bacteria,1R81D@1224|Proteobacteria,1S7RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
XH3_k127_4539272_3	1379698.RBG1_1C00001G0505	0.0008199	48.0	COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
XH3_k127_4539272_0	1227739.Hsw_3239	2.978e-30	140.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
XH3_k127_4539272_2	909663.KI867150_gene2065	6.14e-23	104.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
XH3_k127_4539272_1	1379698.RBG1_1C00001G0502	5.27e-28	123.0	COG1729@1|root,COG1729@2|Bacteria,2NQ0B@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
XH3_k127_4540400_0	485918.Cpin_2593	9.917e-48	190.0	COG1470@1|root,COG1470@2|Bacteria,4P0GS@976|Bacteroidetes	976|Bacteroidetes	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_4540400_1	329726.AM1_4939	6.373e-31	132.0	COG0591@1|root,COG0591@2|Bacteria,1G3QJ@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
XH3_k127_454343_1	709991.Odosp_1116	5.606e-49	181.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,2FNP7@200643|Bacteroidia,22W5Y@171551|Porphyromonadaceae	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
XH3_k127_454343_0	1203611.KB894542_gene765	2.963e-62	222.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,2FNP7@200643|Bacteroidia,22UPH@171550|Rikenellaceae	976|Bacteroidetes	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
XH3_k127_454343_3	396588.Tgr7_1546	1.916e-23	113.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1WWKI@135613|Chromatiales	135613|Chromatiales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_7
XH3_k127_454343_2	697281.Mahau_1930	4.802e-42	159.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,42FAG@68295|Thermoanaerobacterales	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
XH3_k127_4548670_0	1519464.HY22_09070	8.04e-96	338.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	pepN1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
XH3_k127_4548670_1	882.DVU_2683	5.522e-86	293.0	COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,42NEP@68525|delta/epsilon subdivisions,2WPFQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
XH3_k127_4586067_0	521045.Kole_0573	1.591e-79	274.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	asrB	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K02823,ko:K16951	ko00240,ko00920,ko01100,ko01120,map00240,map00920,map01100,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS12555	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
XH3_k127_4586067_3	273075.Ta0045m	9.406e-13	81.0	COG0243@1|root,arCOG01491@2157|Archaea,2XT94@28890|Euryarchaeota	28890|Euryarchaeota	C	COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing	narB	-	1.17.1.9,1.20.2.1,1.20.9.1,1.7.7.2	ko:K00123,ko:K00367,ko:K00372,ko:K08356	ko00630,ko00680,ko00910,ko01100,ko01120,ko01200,map00630,map00680,map00910,map01100,map01120,map01200	M00531	R00519,R00791,R00798,R01106	RC02796,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.6	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
XH3_k127_4586067_2	639282.DEFDS_0246	1.611e-28	121.0	COG1142@1|root,COG1142@2|Bacteria,2GG5C@200930|Deferribacteres	200930|Deferribacteres	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_4586067_1	857293.CAAU_1262	1.462e-49	188.0	COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,25E6Z@186801|Clostridia,36EBY@31979|Clostridiaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
XH3_k127_4620032_1	880073.Calab_3536	1.656e-103	344.0	COG0404@1|root,COG0404@2|Bacteria,2NNSR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
XH3_k127_4620032_0	1209989.TepiRe1_2353	3.228e-198	639.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42FPS@68295|Thermoanaerobacterales	186801|Clostridia	J	TIGRFAM Translation elongation factor	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
XH3_k127_4636971_0	1499967.BAYZ01000059_gene4772	0.0	1050.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.12.1.3	ko:K18331	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
XH3_k127_4636971_1	880073.Calab_1429	3.041e-54	195.0	COG1905@1|root,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria	2|Bacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.12.1.4,1.6.5.3	ko:K00334,ko:K17999	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
XH3_k127_4636971_2	880073.Calab_1430	1.459e-17	86.0	COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
XH3_k127_464225_1	760568.Desku_3372	2.587e-26	126.0	COG1520@1|root,COG1520@2|Bacteria,1W4I3@1239|Firmicutes,254ZP@186801|Clostridia	186801|Clostridia	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_464225_0	765420.OSCT_1998	3.605e-37	149.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH3_k127_4645115_0	1125863.JAFN01000001_gene3450	1.581e-140	455.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
XH3_k127_4645115_1	246194.CHY_1992	2.824e-103	347.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,42EK7@68295|Thermoanaerobacterales	186801|Clostridia	C	Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain	nfnA	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
XH3_k127_4666595_0	1499967.BAYZ01000013_gene6446	9.195e-149	484.0	COG0686@1|root,COG0686@2|Bacteria,2NNTE@2323|unclassified Bacteria	2|Bacteria	E	Alanine dehydrogenase/PNT, N-terminal domain	sdh	-	1.5.1.7,1.5.1.8,1.5.1.9	ko:K00290,ko:K14157	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R00716,R02313	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
XH3_k127_4666595_1	1047013.AQSP01000045_gene108	1.06e-144	471.0	COG1748@1|root,COG1748@2|Bacteria,2NNZ1@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lys2	-	1.5.1.10	ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R02315	RC00215,RC00225	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
XH3_k127_4666595_2	639282.DEFDS_0342	4.721e-25	111.0	COG1633@1|root,COG1633@2|Bacteria,2GFJQ@200930|Deferribacteres	200930|Deferribacteres	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH3_k127_4666595_3	1121459.AQXE01000001_gene2715	6.745e-18	89.0	COG1633@1|root,COG1633@2|Bacteria,1N997@1224|Proteobacteria,42VKE@68525|delta/epsilon subdivisions,2WRKQ@28221|Deltaproteobacteria,2MC42@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH3_k127_47001_2	644281.MFS40622_0811	3.861e-25	119.0	COG0715@1|root,arCOG01803@2157|Archaea,2XV0M@28890|Euryarchaeota,23Q8J@183939|Methanococci	183939|Methanococci	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
XH3_k127_47001_0	1137268.AZXF01000019_gene406	7.983e-78	275.0	COG0019@1|root,COG0019@2|Bacteria,2GIT5@201174|Actinobacteria,4EM7P@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC,PP-binding
XH3_k127_47001_3	583355.Caka_0186	2.197e-20	98.0	2CCSR@1|root,30U27@2|Bacteria,46Y6M@74201|Verrucomicrobia,3K9T2@414999|Opitutae	414999|Opitutae	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
XH3_k127_47001_5	1231185.BAMP01000057_gene4794	2.404e-19	99.0	COG2014@1|root,COG2014@2|Bacteria,1P6T2@1224|Proteobacteria	1224|Proteobacteria	S	Putative heavy-metal chelation	-	-	-	-	-	-	-	-	-	-	-	-	DUF364
XH3_k127_47001_6	1263831.F543_23390	3.893e-14	85.0	COG2267@1|root,COG2267@2|Bacteria,1NJPZ@1224|Proteobacteria,1TFEK@1236|Gammaproteobacteria,1Y7V6@135625|Pasteurellales	135625|Pasteurellales	I	protein of Bacteria UniRef RepID	-	-	-	-	-	-	-	-	-	-	-	-	DUF1749,Hydrolase_4
XH3_k127_47001_4	1278073.MYSTI_02461	2.126e-19	101.0	COG1378@1|root,COG1378@2|Bacteria,1N9ZU@1224|Proteobacteria,42NVG@68525|delta/epsilon subdivisions,2WMD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
XH3_k127_47001_1	1123008.KB905695_gene2524	3.342e-31	134.0	COG0793@1|root,COG0793@2|Bacteria,4NEK8@976|Bacteroidetes,2FNHK@200643|Bacteroidia,22XCW@171551|Porphyromonadaceae	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
XH3_k127_471361_2	680198.SCAB_38811	0.000307	51.0	COG0438@1|root,COG0438@2|Bacteria,2GJBP@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
XH3_k127_471361_0	234267.Acid_1085	8.893e-79	274.0	COG0123@1|root,COG0123@2|Bacteria,3Y46F@57723|Acidobacteria	57723|Acidobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
XH3_k127_471361_1	1121472.AQWN01000003_gene1609	1.803e-25	110.0	COG3581@1|root,COG3581@2|Bacteria,1TPPP@1239|Firmicutes,249C8@186801|Clostridia,25ZYH@186807|Peptococcaceae	186801|Clostridia	I	PFAM CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2229
XH3_k127_4716541_0	1356852.N008_19355	2.835e-14	86.0	COG1807@1|root,COG1807@2|Bacteria,4NWRT@976|Bacteroidetes,47SWC@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_4716541_1	1313301.AUGC01000007_gene660	1.704e-06	61.0	COG1807@1|root,COG1807@2|Bacteria,4NXEH@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_4720406_0	1121428.DESHY_50090___1	3.561e-76	267.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25ZYA@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
XH3_k127_4720406_2	1379698.RBG1_1C00001G1816	2.845e-54	213.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
XH3_k127_4720406_3	1304874.JAFY01000005_gene1308	2.493e-21	99.0	COG1321@1|root,COG1321@2|Bacteria,3TBFX@508458|Synergistetes	508458|Synergistetes	K	PFAM Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress
XH3_k127_4720406_1	660470.Theba_1382	6.506e-59	216.0	COG0428@1|root,COG0428@2|Bacteria,2GCHV@200918|Thermotogae	200918|Thermotogae	P	PFAM zinc iron permease	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
XH3_k127_4732746_1	102129.Lepto7375DRAFT_3669	1.531e-67	245.0	COG2059@1|root,COG2059@2|Bacteria,1G37Z@1117|Cyanobacteria,1HA7A@1150|Oscillatoriales	1117|Cyanobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
XH3_k127_4732746_0	1379698.RBG1_1C00001G1789	3.304e-91	340.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
XH3_k127_4772139_1	1121423.JONT01000003_gene999	1.768e-22	110.0	COG1520@1|root,COG1520@2|Bacteria,1W4I3@1239|Firmicutes	1239|Firmicutes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_4772139_0	665571.STHERM_c17910	3.254e-51	186.0	COG0388@1|root,COG0388@2|Bacteria,2J9CB@203691|Spirochaetes	203691|Spirochaetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
XH3_k127_4786217_1	1379698.RBG1_1C00001G0864	1.025e-34	152.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744,ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA,OstA_C
XH3_k127_4786217_0	765912.Thimo_1834	1.278e-64	228.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,1WXXG@135613|Chromatiales	135613|Chromatiales	L	PFAM HhH-GPD	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
XH3_k127_4786217_2	404380.Gbem_3502	1.199e-30	123.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_1671	Transgly,Transpeptidase
XH3_k127_4813475_0	1123393.KB891316_gene1793	1.138e-49	194.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF_2,GGDEF,PAS_4,PAS_9
XH3_k127_484681_0	986075.CathTA2_0959	1.208e-139	454.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
XH3_k127_484681_1	1379698.RBG1_1C00001G1846	2.46e-125	429.0	COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
XH3_k127_4880398_1	1125863.JAFN01000001_gene1642	1.143e-07	64.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
XH3_k127_4880398_0	477974.Daud_1184	8.117e-76	264.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,261NP@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
XH3_k127_4898050_0	391598.FBBAL38_09852	4.288e-92	321.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
XH3_k127_4898050_1	1379698.RBG1_1C00001G0099	1.291e-09	61.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
XH3_k127_4906351_2	435908.IDSA_10360	0.0005343	46.0	COG5652@1|root,COG5652@2|Bacteria,1N3WP@1224|Proteobacteria,1SACK@1236|Gammaproteobacteria,2QGGW@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
XH3_k127_4906351_0	720554.Clocl_0107	1.74e-51	189.0	COG1394@1|root,COG1394@2|Bacteria,1TQ1Y@1239|Firmicutes,247TC@186801|Clostridia,3WHIG@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
XH3_k127_4906351_1	118005.AWNK01000002_gene1744	1.785e-29	121.0	arCOG11509@1|root,31KIR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_499089_1	1280390.CBQR020000129_gene3206	7.299e-46	172.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,26R9D@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
XH3_k127_499089_2	370438.PTH_2212	1.281e-43	165.0	COG2110@1|root,COG2755@1|root,COG2110@2|Bacteria,COG2755@2|Bacteria,1VDE2@1239|Firmicutes,24N6X@186801|Clostridia,262J2@186807|Peptococcaceae	186801|Clostridia	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
XH3_k127_499089_4	580327.Tthe_2551	3.5e-35	143.0	COG1762@1|root,COG1762@2|Bacteria,1VA2N@1239|Firmicutes,24N94@186801|Clostridia,42H1N@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
XH3_k127_499089_6	68170.KL590533_gene5269	0.0007801	47.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4E6RZ@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
XH3_k127_499089_0	264732.Moth_2519	4.704e-79	282.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,42FFQ@68295|Thermoanaerobacterales	186801|Clostridia	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
XH3_k127_499089_5	391625.PPSIR1_35072	4.899e-15	86.0	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QPK@68525|delta/epsilon subdivisions,2WN58@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Single-stranded nucleic acid binding R3H	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
XH3_k127_499089_3	945713.IALB_3204	9.791e-39	151.0	COG0706@1|root,COG0706@2|Bacteria	2|Bacteria	U	membrane insertase activity	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
XH3_k127_5017924_2	449447.MAE_55290	5.129e-16	80.0	COG0662@1|root,COG0662@2|Bacteria,1G5PK@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
XH3_k127_5017924_0	880073.Calab_0341	5.405e-183	586.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
XH3_k127_5017924_1	439235.Dalk_4005	7.339e-17	91.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,42RIS@68525|delta/epsilon subdivisions,2WMWC@28221|Deltaproteobacteria,2MJR1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
XH3_k127_5019799_0	622637.KE124774_gene3265	2.675e-139	454.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,2TUA8@28211|Alphaproteobacteria,36ZFU@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase,CbiA
XH3_k127_5019799_3	1131462.DCF50_p201	2.94e-08	63.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
XH3_k127_5019799_1	187272.Mlg_2711	6.683e-27	117.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,1S7NG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arsenical resistance operon trans-acting repressor arsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
XH3_k127_5019799_2	278963.ATWD01000001_gene4647	8.67e-13	70.0	COG0640@1|root,COG0640@2|Bacteria,3Y7J1@57723|Acidobacteria,2JMRU@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
XH3_k127_5020335_2	2074.JNYD01000001_gene6273	0.0001663	49.0	COG5662@1|root,COG5662@2|Bacteria,2HG2K@201174|Actinobacteria,4E2QA@85010|Pseudonocardiales	201174|Actinobacteria	K	AntiSigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	zf-HC2
XH3_k127_5020335_0	857087.Metme_2792	8.247e-32	131.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1XEK8@135618|Methylococcales	135618|Methylococcales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH3_k127_5020335_1	573370.DMR_01540	1.598e-13	71.0	COG3678@1|root,COG3678@2|Bacteria,1NREX@1224|Proteobacteria	1224|Proteobacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_5028139_4	1191523.MROS_0752	2.941e-12	80.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
XH3_k127_5028139_2	517417.Cpar_1512	7.136e-14	80.0	COG0810@1|root,COG0810@2|Bacteria,1FE18@1090|Chlorobi	1090|Chlorobi	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
XH3_k127_5028139_3	717231.Flexsi_1498	7.157e-14	77.0	COG0848@1|root,COG0848@2|Bacteria,2GFX6@200930|Deferribacteres	200930|Deferribacteres	U	Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
XH3_k127_5028139_5	1349822.NSB1T_06370	8.006e-05	51.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,2FRY4@200643|Bacteroidia,22Y92@171551|Porphyromonadaceae	976|Bacteroidetes	U	Biopolymer transporter ExbD	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
XH3_k127_5028139_1	309807.SRU_1681	8.38e-38	150.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,1FIYM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
XH3_k127_5028139_0	713586.KB900536_gene1797	1.504e-81	286.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1WVY3@135613|Chromatiales	135613|Chromatiales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
XH3_k127_5035887_2	459349.CLOAM0985	1.002e-09	72.0	COG1361@1|root,COG1361@2|Bacteria,2NQI0@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
XH3_k127_5035887_1	1144275.COCOR_01829	6.39e-14	86.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria,2Z0FT@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,VWD,fn3
XH3_k127_5035887_0	381764.Fnod_0182	5.26e-49	181.0	COG0272@1|root,COG0272@2|Bacteria,2GCF6@200918|Thermotogae	200918|Thermotogae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
XH3_k127_503835_1	1340493.JNIF01000003_gene2343	2.396e-20	103.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
XH3_k127_503835_0	1499967.BAYZ01000080_gene958	1.766e-84	304.0	COG1044@1|root,COG1044@2|Bacteria,2NQT1@2323|unclassified Bacteria	2|Bacteria	M	SpoIVB peptidase S55	-	-	2.7.7.24	ko:K00973,ko:K02414,ko:K21449	ko00521,ko00523,ko00525,ko01130,ko02040,map00521,map00523,map00525,map01130,map02040	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000,ko02035	1.B.40.2	-	-	AMP-binding,APH,DUF4114,DUF4842,Hexapep,PP-binding,Peptidase_S55
XH3_k127_5060463_2	887062.HGR_12347	1.115e-06	56.0	COG4447@1|root,COG4447@2|Bacteria,1R84R@1224|Proteobacteria,2VMQ1@28216|Betaproteobacteria,4AEMT@80864|Comamonadaceae	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
XH3_k127_5060463_0	1499967.BAYZ01000193_gene3921	6.103e-88	299.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
XH3_k127_5060463_1	158189.SpiBuddy_1116	2.257e-11	67.0	COG0446@1|root,COG0446@2|Bacteria,2J5ZG@203691|Spirochaetes	203691|Spirochaetes	C	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Pyr_redox_2
XH3_k127_527642_0	269799.Gmet_1954	2.063e-144	476.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,43T3U@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
XH3_k127_5283279_2	1304284.L21TH_1051	2.338e-31	130.0	COG0534@1|root,COG0534@2|Bacteria,1UZDQ@1239|Firmicutes,24F5D@186801|Clostridia,36VMW@31979|Clostridiaceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
XH3_k127_5283279_4	1382306.JNIM01000001_gene3668	1.236e-09	70.0	COG0454@1|root,COG0456@2|Bacteria,2G9G9@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
XH3_k127_5283279_3	1173025.GEI7407_0366	3.68e-19	95.0	COG4956@1|root,COG4956@2|Bacteria,1FZYF@1117|Cyanobacteria,1H7EU@1150|Oscillatoriales	1117|Cyanobacteria	S	Integral membrane protein (Pin domain superfamily)	ycf81	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	PIN_4,TRAM
XH3_k127_5283279_0	1123252.ATZF01000011_gene3207	7.494e-154	499.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,27BBD@186824|Thermoactinomycetaceae	91061|Bacilli	L	KaiC	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
XH3_k127_5283279_1	596152.DesU5LDRAFT_2279	7.869e-87	297.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2M7ZB@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
XH3_k127_5286160_2	5786.XP_003287049.1	8.955e-33	148.0	COG1404@1|root,KOG4266@2759|Eukaryota	2759|Eukaryota	O	serine-type endopeptidase activity	-	-	3.4.21.112	ko:K08653	ko04141,map04141	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
XH3_k127_5286160_0	1047013.AQSP01000059_gene2098	1.813e-160	512.0	COG0451@1|root,COG0451@2|Bacteria,2NQD6@2323|unclassified Bacteria	2|Bacteria	GM	RmlD substrate binding domain	ltd	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	Epimerase
XH3_k127_5286160_1	246194.CHY_1513	2.708e-71	248.0	COG3294@1|root,COG3294@2|Bacteria,1UXSS@1239|Firmicutes,24A8Y@186801|Clostridia,42FRF@68295|Thermoanaerobacterales	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
XH3_k127_5286160_3	706434.HMPREF9429_00570	8.796e-14	77.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4H47Z@909932|Negativicutes	909932|Negativicutes	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
XH3_k127_5300521_0	1379698.RBG1_1C00001G0527	1.81e-128	419.0	COG1960@1|root,COG1960@2|Bacteria,2NNXA@2323|unclassified Bacteria	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH3_k127_5300521_1	767817.Desgi_2500	4.062e-126	417.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,260RX@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
XH3_k127_5300521_2	459349.CLOAM0010	9.884e-64	236.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
XH3_k127_5322538_0	391625.PPSIR1_37514	1.379e-26	114.0	2EG8Z@1|root,33A0S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_5322538_1	479434.Sthe_1913	1.428e-08	62.0	COG1664@1|root,COG1664@2|Bacteria,2G79N@200795|Chloroflexi,27Y9Z@189775|Thermomicrobia	189775|Thermomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_5357327_1	1121405.dsmv_2114	2.033e-39	157.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2MI8G@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Belongs to the TtcA family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
XH3_k127_5357327_0	555079.Toce_0825	4.929e-150	490.0	COG1109@1|root,COG1109@2|Bacteria,1TS6S@1239|Firmicutes,2491F@186801|Clostridia,42FFK@68295|Thermoanaerobacterales	186801|Clostridia	G	alpha beta alpha domain I	manB	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
XH3_k127_5357327_2	160860.XP_007336628.1	2.338e-11	72.0	COG0484@1|root,KOG0714@2759|Eukaryota,39TYJ@33154|Opisthokonta,3P0U5@4751|Fungi,3V0WV@5204|Basidiomycota,2284J@155619|Agaricomycetes,3H238@355688|Agaricomycetes incertae sedis	4751|Fungi	O	DnaJ-domain-containing protein	-	GO:0003674,GO:0005488,GO:0005515,GO:0030544,GO:0031072	-	ko:K17867	-	-	-	-	ko00000,ko03012	-	-	-	DnaJ
XH3_k127_5357904_0	471853.Bcav_1705	1.019e-62	228.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
XH3_k127_5370193_0	1121373.KB903664_gene2542	2.714e-56	218.0	COG1404@1|root,COG1520@1|root,COG3291@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NF1M@976|Bacteroidetes,47KVM@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
XH3_k127_5370349_0	1379698.RBG1_1C00001G1842	6.546e-34	143.0	2E3NC@1|root,32YKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_538565_3	768670.Calni_1028	8.849e-17	94.0	COG0706@1|root,COG0706@2|Bacteria,2GF6E@200930|Deferribacteres	200930|Deferribacteres	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
XH3_k127_538565_2	1392502.JNIO01000007_gene982	7.02e-22	99.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4H5K3@909932|Negativicutes	909932|Negativicutes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
XH3_k127_538565_5	161156.JQKW01000006_gene1100	9.148e-09	62.0	COG0594@1|root,COG0594@2|Bacteria,2GI1P@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
XH3_k127_538565_4	706587.Desti_3934	1.632e-13	70.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,42WSU@68525|delta/epsilon subdivisions,2WSI8@28221|Deltaproteobacteria,2MSEK@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
XH3_k127_538565_0	1033743.CAES01000098_gene2693	3.501e-75	276.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,26S58@186822|Paenibacillaceae	91061|Bacilli	V	Multidrug ABC transporter ATP-binding protein	yheI	-	-	ko:K18216,ko:K18889	ko02010,map02010	M00635,M00707	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
XH3_k127_538565_1	671143.DAMO_2494	2.464e-68	239.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
XH3_k127_5396343_2	264732.Moth_1694	2.063e-34	135.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,42EMN@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
XH3_k127_5396343_0	290318.Cvib_1120	1.435e-89	305.0	COG1209@1|root,COG1209@2|Bacteria,1FD8Z@1090|Chlorobi	1090|Chlorobi	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
XH3_k127_5396343_1	760568.Desku_3301	3.242e-48	182.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,25ZZA@186807|Peptococcaceae	186801|Clostridia	G	Sugar isomerase (SIS)	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
XH3_k127_5422308_3	596151.DesfrDRAFT_3030	0.0001504	52.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42T19@68525|delta/epsilon subdivisions,2WQ0M@28221|Deltaproteobacteria,2M91B@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
XH3_k127_5422308_2	34740.HMEL006868-PA	1.034e-15	90.0	COG0457@1|root,KOG0548@2759|Eukaryota,38GAN@33154|Opisthokonta,3BEXQ@33208|Metazoa,3CSRU@33213|Bilateria,41U12@6656|Arthropoda,3SIUT@50557|Insecta,4449J@7088|Lepidoptera	33208|Metazoa	O	Tetratricopeptide repeat	TTC28	GO:0000922,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005813,GO:0005815,GO:0005819,GO:0005856,GO:0007346,GO:0008150,GO:0015630,GO:0019899,GO:0019900,GO:0030496,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044430,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051233,GO:0051726,GO:0065007,GO:0072686,GO:0097431,GO:1990023	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_16,TPR_7,TPR_8
XH3_k127_5422308_1	1288298.rosmuc_04178	2.28e-16	85.0	COG4916@1|root,COG4916@2|Bacteria,1R81D@1224|Proteobacteria,2UBXF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
XH3_k127_5422308_0	1379698.RBG1_1C00001G1438	5.611e-40	166.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
XH3_k127_5450407_0	667014.Thein_2073	5.88e-32	124.0	COG0543@1|root,COG0543@2|Bacteria,2GIAB@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
XH3_k127_5450407_1	670487.Ocepr_0854	1.97e-16	86.0	COG1881@1|root,COG1881@2|Bacteria,1WKIM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
XH3_k127_545046_1	1121127.JAFA01000004_gene1254	1.8e-145	475.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,1K0DR@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
XH3_k127_545046_0	1288494.EBAPG3_25360	5.395e-149	485.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,3723J@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
XH3_k127_545046_2	2325.TKV_c16600	2.265e-91	308.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,42FFV@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Radical SAM domain protein	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
XH3_k127_545046_3	1121423.JONT01000008_gene814	8.983e-32	128.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,261JB@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
XH3_k127_5481629_4	500632.CLONEX_04113	0.0008164	48.0	COG4640@1|root,COG4640@2|Bacteria,1VEU9@1239|Firmicutes,24S06@186801|Clostridia	186801|Clostridia	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
XH3_k127_5481629_2	768706.Desor_0424	2.398e-17	86.0	COG4818@1|root,COG4818@2|Bacteria,1VG59@1239|Firmicutes,25I1U@186801|Clostridia,2663E@186807|Peptococcaceae	186801|Clostridia	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_5481629_0	1121104.AQXH01000001_gene1224	2.257e-72	257.0	COG0438@1|root,COG0438@2|Bacteria,4NM8R@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
XH3_k127_5481629_1	1121930.AQXG01000003_gene2517	1.702e-40	170.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
XH3_k127_5481629_3	357808.RoseRS_4228	1.819e-08	61.0	COG2244@1|root,COG2244@2|Bacteria,2G8GU@200795|Chloroflexi,3767K@32061|Chloroflexia	32061|Chloroflexia	S	virulence factor MVIN family protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
XH3_k127_5514498_1	880073.Calab_0484	9.548e-35	149.0	COG1629@1|root,COG4771@2|Bacteria,2NR02@2323|unclassified Bacteria	2|Bacteria	P	TonB dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
XH3_k127_5514498_0	379066.GAU_1168	4.067e-130	422.0	COG1012@1|root,COG1012@2|Bacteria,1ZST9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
XH3_k127_5521193_0	864073.HFRIS_024127	1.207e-09	70.0	COG0500@1|root,COG2226@2|Bacteria,1PN45@1224|Proteobacteria,2VNPX@28216|Betaproteobacteria,4741X@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
XH3_k127_5574653_1	1501391.LG35_05925	7.465e-22	106.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22V8H@171550|Rikenellaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
XH3_k127_5574653_0	865937.Gilli_2176	4.739e-23	108.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia,2P5K9@244698|Gillisia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
XH3_k127_5609019_0	762982.HMPREF9442_03088	8.442e-38	164.0	COG1520@1|root,COG4870@1|root,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
XH3_k127_5668517_1	1259795.ARJK01000002_gene39	2.282e-22	100.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,24RHI@186801|Clostridia,42H08@68295|Thermoanaerobacterales	186801|Clostridia	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
XH3_k127_5668517_0	1379698.RBG1_1C00001G0356	9.924e-62	234.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
XH3_k127_5695177_0	1168289.AJKI01000040_gene3118	2.166e-06	61.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,2FN9K@200643|Bacteroidia,3XJXH@558415|Marinilabiliaceae	976|Bacteroidetes	S	Kelch motif	nanM	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
XH3_k127_5771077_2	1123023.JIAI01000010_gene8403	5.849e-08	64.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria,4E0KS@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
XH3_k127_5771077_1	411464.DESPIG_01241	3.078e-13	78.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2M7YQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
XH3_k127_5771077_0	7230.FBpp0170383	1.13e-18	95.0	COG0438@1|root,KOG1111@2759|Eukaryota,38ENZ@33154|Opisthokonta,3BE7N@33208|Metazoa,3CZ28@33213|Bilateria,41VXB@6656|Arthropoda,3SGF9@50557|Insecta,44ZSS@7147|Diptera,45T37@7214|Drosophilidae	33208|Metazoa	IMO	It is involved in the biological process described with GPI anchor biosynthetic process	PIGA	GO:0000506,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006464,GO:0006497,GO:0006505,GO:0006506,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006661,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009247,GO:0009893,GO:0009987,GO:0010033,GO:0012505,GO:0016020,GO:0016021,GO:0016254,GO:0016740,GO:0016757,GO:0016758,GO:0017176,GO:0019222,GO:0019538,GO:0019637,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0032991,GO:0034097,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0042175,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046467,GO:0046474,GO:0046486,GO:0046488,GO:0048518,GO:0050789,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071310,GO:0071345,GO:0071704,GO:0090407,GO:0098796,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1903509,GO:1990234,GO:1990823,GO:1990830	2.4.1.198	ko:K03857	ko00563,ko01100,map00563,map01100	M00065	R05916	-	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glycos_transf_1,PIGA
XH3_k127_5786465_2	381666.H16_A2194	1.499e-44	168.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VZ53@28216|Betaproteobacteria,1K5YJ@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Elongation factor P	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
XH3_k127_5786465_3	880073.Calab_2084	2.47e-07	64.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,FlgD_ig,Peptidase_S74
XH3_k127_5786465_1	1379698.RBG1_1C00001G1092	2.146e-63	244.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
XH3_k127_5786465_0	644282.Deba_1534	1.639e-95	325.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42N6X@68525|delta/epsilon subdivisions,2WJIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
XH3_k127_5787217_0	673860.AciM339_1221	3.95e-95	338.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota	28890|Euryarchaeota	K	DEAD H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C
XH3_k127_5787217_2	880073.Calab_3224	2.213e-15	81.0	2CCSR@1|root,32RWC@2|Bacteria	2|Bacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
XH3_k127_5787217_1	518766.Rmar_1322	2.05e-46	183.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1FIXH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
XH3_k127_5787217_3	1341155.FSS13T_13870	0.0003259	51.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,4NJHV@976|Bacteroidetes,1IMXD@117743|Flavobacteriia,2NV4Y@237|Flavobacterium	976|Bacteroidetes	O	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
XH3_k127_5823370_1	945713.IALB_2269	2.728e-59	214.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
XH3_k127_5823370_0	671143.DAMO_0004	6.85e-64	237.0	COG0612@1|root,COG0612@2|Bacteria,2NPE5@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
XH3_k127_5823370_2	83406.HDN1F_19490	1.183e-16	86.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1J4IJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Zn-dependent peptidases	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
XH3_k127_5831021_3	269799.Gmet_2849	6.038e-44	167.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,43TCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
XH3_k127_5831021_0	661478.OP10G_1978	1.123e-105	374.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,COesterase,Esterase,Peptidase_S9
XH3_k127_5831021_2	56780.SYN_03131	2.217e-46	173.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,42T3J@68525|delta/epsilon subdivisions,2X5P0@28221|Deltaproteobacteria,2MRWT@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
XH3_k127_5831021_1	1379698.RBG1_1C00001G0380	1.179e-47	183.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
XH3_k127_5835221_1	688269.Theth_0283	9.81e-119	387.0	COG0056@1|root,COG0056@2|Bacteria,2GCEZ@200918|Thermotogae	200918|Thermotogae	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
XH3_k127_5835221_2	234267.Acid_0464	3.949e-42	172.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
XH3_k127_5835221_0	309803.CTN_0848	8.209e-196	621.0	COG0055@1|root,COG0055@2|Bacteria,2GCCZ@200918|Thermotogae	200918|Thermotogae	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
XH3_k127_5835221_3	1336208.JADY01000004_gene3512	7.042e-14	81.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2UBXX@28211|Alphaproteobacteria,2JTEK@204441|Rhodospirillales	204441|Rhodospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
XH3_k127_5837974_4	1121423.JONT01000011_gene244	2.601e-16	81.0	COG3366@1|root,COG3366@2|Bacteria,1UHXB@1239|Firmicutes,24PK4@186801|Clostridia	186801|Clostridia	S	PFAM nucleoside recognition domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gate
XH3_k127_5837974_0	1158345.JNLL01000001_gene1282	1.591e-102	351.0	COG0260@1|root,COG0260@2|Bacteria,2G3TV@200783|Aquificae	200783|Aquificae	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
XH3_k127_5837974_2	1125863.JAFN01000001_gene2598	1.833e-68	244.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria	1224|Proteobacteria	P	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system	znuC	-	-	ko:K02074,ko:K09817	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
XH3_k127_5837974_1	1125863.JAFN01000001_gene2599	2.568e-81	280.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WPQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
XH3_k127_5837974_3	1499967.BAYZ01000090_gene4941	3.441e-25	121.0	2DDA6@1|root,2ZH98@2|Bacteria	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT
XH3_k127_5837974_5	450851.PHZ_c3081	0.0001803	47.0	COG2202@1|root,COG3920@1|root,COG2202@2|Bacteria,COG3920@2|Bacteria,1NWNJ@1224|Proteobacteria,2U3RV@28211|Alphaproteobacteria,2KGXW@204458|Caulobacterales	204458|Caulobacterales	T	HWE histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HWE_HK,PAS_3
XH3_k127_5840156_0	1379698.RBG1_1C00001G1315	1.611e-82	284.0	COG0463@1|root,COG0463@2|Bacteria,2NP2G@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
XH3_k127_5840156_2	634497.HAH_1205	9.479e-19	100.0	COG0392@1|root,arCOG00899@2157|Archaea,2Y788@28890|Euryarchaeota,240HY@183963|Halobacteria	183963|Halobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
XH3_k127_5840156_1	637390.AFOH01000039_gene2421	1.59e-27	116.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,2NCCE@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
XH3_k127_5841289_3	1499967.BAYZ01000084_gene3992	5.548e-43	168.0	COG2045@1|root,COG2045@2|Bacteria,2NPF1@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the ComB family	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
XH3_k127_5841289_0	429009.Adeg_1283	6.675e-146	476.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,42F16@68295|Thermoanaerobacterales	186801|Clostridia	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
XH3_k127_5841289_2	1293054.HSACCH_01254	8.574e-47	181.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3WAPV@53433|Halanaerobiales	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
XH3_k127_5841289_1	293826.Amet_2489	8.972e-88	301.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,36E1G@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the peptidase M24B family	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
XH3_k127_5841289_4	449447.MAE_26720	4.534e-32	139.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria	1117|Cyanobacteria	U	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12,TPR_7
XH3_k127_5841289_5	909613.UO65_2013	6.954e-28	130.0	COG1404@1|root,COG1404@2|Bacteria,2IEGJ@201174|Actinobacteria,4DXZF@85010|Pseudonocardiales	201174|Actinobacteria	O	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,Malectin,Peptidase_S8
XH3_k127_5867529_2	1121472.AQWN01000007_gene1067	3.924e-49	181.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,261UB@186807|Peptococcaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
XH3_k127_5867529_1	1379698.RBG1_1C00001G1787	1.403e-77	293.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	DUF1863,PQQ_2
XH3_k127_5867529_0	1379698.RBG1_1C00001G0991	7.775e-82	298.0	COG2911@1|root,COG2931@1|root,COG4447@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4447@2|Bacteria,2NR5X@2323|unclassified Bacteria	2|Bacteria	Q	FlgD Ig-like domain	-	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_3,DUF1735,Laminin_G_3
XH3_k127_58854_2	243231.GSU0492	1.481e-64	227.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,43U9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
XH3_k127_58854_1	1304872.JAGC01000005_gene1713	4.869e-94	316.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MRV@68525|delta/epsilon subdivisions,2WK9C@28221|Deltaproteobacteria,2M8SQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
XH3_k127_58854_0	1094980.Mpsy_2769	6.629e-98	334.0	COG0674@1|root,arCOG01606@2157|Archaea,2XSUJ@28890|Euryarchaeota,2N91I@224756|Methanomicrobia	224756|Methanomicrobia	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
XH3_k127_5895884_3	102129.Lepto7375DRAFT_1482	1.988e-22	101.0	COG0655@1|root,COG0655@2|Bacteria,1GB8R@1117|Cyanobacteria,1HDV7@1150|Oscillatoriales	1117|Cyanobacteria	S	Nadph-dependent fmn reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
XH3_k127_5895884_1	431943.CKL_2514	3.78e-48	178.0	COG0716@1|root,COG0716@2|Bacteria,1UFVT@1239|Firmicutes,24K47@186801|Clostridia,36RYQ@31979|Clostridiaceae	186801|Clostridia	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_5895884_2	604354.TSIB_0185	6.241e-25	112.0	COG0716@1|root,arCOG00519@2157|Archaea,2XXTN@28890|Euryarchaeota,24487@183968|Thermococci	183968|Thermococci	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
XH3_k127_5895884_0	374847.Kcr_0638	1.368e-88	303.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
XH3_k127_5906743_1	1379698.RBG1_1C00001G1508	1.136e-28	119.0	2E4KV@1|root,32ZFU@2|Bacteria,2NQ0D@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
XH3_k127_5906743_0	1134413.ANNK01000062_gene2329	3.479e-38	156.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB5M@91061|Bacilli,1ZDSD@1386|Bacillus	91061|Bacilli	J	Poly A polymerase head domain	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
XH3_k127_5921440_1	1123508.JH636443_gene5111	2.042e-27	121.0	COG1207@1|root,COG1207@2|Bacteria,2IXBV@203682|Planctomycetes	203682|Planctomycetes	M	Sugar nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_4
XH3_k127_5921440_2	903814.ELI_2336	0.0004509	46.0	COG1765@1|root,COG1765@2|Bacteria,1UKFU@1239|Firmicutes,25FW0@186801|Clostridia,25WI7@186806|Eubacteriaceae	186801|Clostridia	O	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
XH3_k127_5921440_0	640511.BC1002_6158	1.103e-81	282.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,2VIYM@28216|Betaproteobacteria,1K16U@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5,3.5.1.1	ko:K01424,ko:K13051	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
XH3_k127_5942916_0	1122179.KB890436_gene1334	4.186e-37	156.0	COG2304@1|root,COG2304@2|Bacteria,4NK2W@976|Bacteroidetes	976|Bacteroidetes	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	OmpA,VIT,VWA,VWA_3
XH3_k127_5942916_1	1192034.CAP_8646	2.329e-05	52.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
XH3_k127_5970693_2	1457250.BBMO01000001_gene1374	5.788e-13	69.0	arCOG09236@1|root,arCOG09236@2157|Archaea,2XYRW@28890|Euryarchaeota,23X7P@183963|Halobacteria	183963|Halobacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_5970693_1	1379698.RBG1_1C00001G0687	1.276e-109	370.0	COG1109@1|root,COG1109@2|Bacteria,2NNM3@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
XH3_k127_5970693_0	349161.Dred_0295	7.414e-127	419.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,2608Z@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
XH3_k127_5986052_3	1120972.AUMH01000007_gene1681	1.652e-09	62.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,277W9@186823|Alicyclobacillaceae	91061|Bacilli	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
XH3_k127_5986052_0	545264.KB898758_gene2690	1.158e-89	309.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales	135613|Chromatiales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
XH3_k127_5986052_1	1232452.BAIB02000016_gene2426	6.243e-54	203.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,268S3@186813|unclassified Clostridiales	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
XH3_k127_5986052_2	391615.ABSJ01000032_gene724	1.08e-18	89.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1J4RF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the MurCDEF family	murC	GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iECP_1309.ECP_0093	Mur_ligase,Mur_ligase_C,Mur_ligase_M
XH3_k127_6035848_0	515635.Dtur_1693	1.8e-152	495.0	COG0215@1|root,COG0215@2|Bacteria	2|Bacteria	J	cysteine-tRNA ligase activity	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
XH3_k127_6035848_2	935948.KE386495_gene1427	3.608e-94	318.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,42EXJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
XH3_k127_6035848_5	1410668.JNKC01000010_gene930	2.916e-09	68.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia,36FAH@31979|Clostridiaceae	186801|Clostridia	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
XH3_k127_6035848_1	56780.SYN_02795	7.742e-128	422.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2X5JC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
XH3_k127_6035848_4	1403819.BATR01000130_gene4573	5.093e-16	92.0	COG2304@1|root,COG2304@2|Bacteria,46UCW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
XH3_k127_6035848_3	1379698.RBG1_1C00001G0202	9.647e-57	203.0	COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
XH3_k127_606055_0	1121428.DESHY_50090___1	1.202e-49	190.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25ZYA@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
XH3_k127_606055_1	1047013.AQSP01000081_gene103	6.972e-30	121.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
XH3_k127_6096235_2	243159.AFE_1487	9.615e-16	83.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1SCVJ@1236|Gammaproteobacteria,2NE16@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
XH3_k127_6096235_1	255470.cbdbA1599	2.381e-75	261.0	2DBX7@1|root,2ZBN4@2|Bacteria,2G8YK@200795|Chloroflexi,34DM1@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
XH3_k127_6096235_0	903818.KI912268_gene823	2.84e-84	287.0	COG3635@1|root,COG3635@2|Bacteria	2|Bacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
XH3_k127_6117287_2	595460.RRSWK_03709	2.171e-20	107.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
XH3_k127_6117287_1	234267.Acid_3682	7.113e-26	124.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_3682|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_6117287_0	679926.Mpet_1361	6.818e-199	633.0	COG0171@1|root,COG0388@1|root,arCOG00062@2157|Archaea,arCOG00069@2157|Archaea,2XUJI@28890|Euryarchaeota,2NBHN@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	-	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
XH3_k127_6117287_3	1095747.HMPREF1049_0794	2.103e-18	96.0	COG0726@1|root,COG0726@2|Bacteria,3788U@32066|Fusobacteria	32066|Fusobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
XH3_k127_6117287_4	862908.BMS_0675	3.716e-09	66.0	COG2821@1|root,COG2821@2|Bacteria,1NIC3@1224|Proteobacteria,433CJ@68525|delta/epsilon subdivisions,2MUE2@213481|Bdellovibrionales,2WXQG@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
XH3_k127_6132204_0	370438.PTH_2814	6.135e-118	393.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,260JV@186807|Peptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
XH3_k127_6132204_3	1123371.ATXH01000021_gene1133	2.57e-14	79.0	COG0712@1|root,COG0712@2|Bacteria,2GHJX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
XH3_k127_6132204_4	1141106.CAIB01000243_gene2175	2.749e-14	79.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,4GYBQ@90964|Staphylococcaceae	91061|Bacilli	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iYO844.BSU36850	ATP-synt_B
XH3_k127_6132204_5	329726.AM1_0892	5.4e-14	76.0	COG0636@1|root,COG0636@2|Bacteria,1G7UT@1117|Cyanobacteria	1117|Cyanobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
XH3_k127_6132204_1	671143.DAMO_2702	2.386e-44	170.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
XH3_k127_6132204_6	690850.Desaf_0827	3.429e-10	65.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42WTD@68525|delta/epsilon subdivisions,2WSRU@28221|Deltaproteobacteria,2MDF1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpZ	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
XH3_k127_6132204_2	635013.TherJR_0274	4.251e-16	85.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,24MPI@186801|Clostridia,261WW@186807|Peptococcaceae	186801|Clostridia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
XH3_k127_6137354_0	391587.KAOT1_12237	8.439e-45	174.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
XH3_k127_6137354_1	1304885.AUEY01000089_gene131	9.446e-35	145.0	COG0823@1|root,COG0823@2|Bacteria,1N5WZ@1224|Proteobacteria,42U16@68525|delta/epsilon subdivisions,2WR4G@28221|Deltaproteobacteria,2MN8S@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
XH3_k127_6155620_3	1379698.RBG1_1C00001G0490	0.0006373	44.0	COG2067@1|root,COG2067@2|Bacteria,2NR8A@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_6155620_0	243231.GSU1402	7.482e-113	373.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,43UDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
XH3_k127_6155620_1	518766.Rmar_0251	7.367e-84	287.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1FIQK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
XH3_k127_6155620_2	926550.CLDAP_11900	1.414e-14	85.0	COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH3_k127_6167673_5	1304888.ATWF01000001_gene635	1.824e-09	65.0	COG1579@1|root,COG1579@2|Bacteria,2GFHX@200930|Deferribacteres	200930|Deferribacteres	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
XH3_k127_6167673_3	861299.J421_3386	1.563e-28	120.0	COG1762@1|root,COG1762@2|Bacteria,1ZTIY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
XH3_k127_6167673_4	324925.Ppha_0095	1.654e-25	112.0	COG0799@1|root,COG0799@2|Bacteria,1FE3F@1090|Chlorobi	1090|Chlorobi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
XH3_k127_6167673_1	1235794.C811_01066	1.245e-51	192.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4CUFP@84998|Coriobacteriia	84998|Coriobacteriia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
XH3_k127_6167673_2	665571.STHERM_c05220	1.647e-34	138.0	COG0203@1|root,COG0203@2|Bacteria,2J841@203691|Spirochaetes	203691|Spirochaetes	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
XH3_k127_6167673_0	1379698.RBG1_1C00001G1568	3.067e-85	294.0	COG0202@1|root,COG0202@2|Bacteria,2NNQQ@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
XH3_k127_6176207_1	225849.swp_3838	2.854e-11	73.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,2Q9MS@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Peptidase M23B	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
XH3_k127_6176207_2	555088.DealDRAFT_2681	1.132e-05	51.0	COG3027@1|root,COG3027@2|Bacteria,1UFX5@1239|Firmicutes,25MWM@186801|Clostridia,42K8N@68298|Syntrophomonadaceae	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
XH3_k127_6176207_0	1379698.RBG1_1C00001G1123	2.565e-145	475.0	COG1418@1|root,COG1418@2|Bacteria,2NNU5@2323|unclassified Bacteria	2|Bacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
XH3_k127_619028_4	218284.CCDN010000001_gene445	2.013e-08	63.0	COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,1ZD6Z@1386|Bacillus	91061|Bacilli	M	cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cna_B,Collagen_bind,Gram_pos_anchor,MucBP
XH3_k127_619028_0	429009.Adeg_0423	5.902e-116	386.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
XH3_k127_619028_1	909663.KI867150_gene222	3.78e-59	208.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2MRQU@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
XH3_k127_619028_3	1220534.B655_0380	1.087e-17	89.0	COG0695@1|root,arCOG02606@2157|Archaea,2Y0MA@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
XH3_k127_619028_2	192952.MM_3270	6.063e-32	127.0	COG4802@1|root,arCOG01100@2157|Archaea,2XXWK@28890|Euryarchaeota,2NAWN@224756|Methanomicrobia	224756|Methanomicrobia	C	Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
XH3_k127_6201199_2	1280952.HJA_06827	9.623e-22	99.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria,43XBR@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	petR	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
XH3_k127_6201199_0	477974.Daud_1392	3.114e-131	428.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,260J0@186807|Peptococcaceae	186801|Clostridia	E	PFAM Extracellular ligand-binding receptor	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
XH3_k127_6201199_1	500633.CLOHIR_00908	6.73e-117	384.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,25QE3@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
XH3_k127_6217889_1	1122921.KB898188_gene338	1.877e-17	96.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,26QNY@186822|Paenibacillaceae	91061|Bacilli	O	CarboxypepD_reg-like domain	bprF	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8
XH3_k127_6217889_0	926550.CLDAP_17040	6.78e-49	184.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
XH3_k127_6244128_4	1121468.AUBR01000024_gene3011	1.542e-23	106.0	COG0370@1|root,COG0370@2|Bacteria,1TQT3@1239|Firmicutes,24MTG@186801|Clostridia,42GUP@68295|Thermoanaerobacterales	186801|Clostridia	P	nucleoside recognition domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gate
XH3_k127_6244128_3	1379698.RBG1_1C00001G0342	5.975e-50	187.0	COG2908@1|root,COG2908@2|Bacteria,2NPKW@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
XH3_k127_6244128_0	269799.Gmet_1232	1.872e-113	388.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,42NEZ@68525|delta/epsilon subdivisions,2WJ5R@28221|Deltaproteobacteria,43U4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
XH3_k127_6244128_2	1125863.JAFN01000001_gene2944	4.547e-54	197.0	COG1014@1|root,COG1014@2|Bacteria,1RAQ4@1224|Proteobacteria,43BEE@68525|delta/epsilon subdivisions,2WN0D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	korC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
XH3_k127_6244128_1	1304888.ATWF01000002_gene320	1.23e-84	290.0	COG1013@1|root,COG1013@2|Bacteria,2GEMM@200930|Deferribacteres	200930|Deferribacteres	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
XH3_k127_6266502_1	443254.Marpi_1007	5.024e-07	59.0	COG1520@1|root,COG1520@2|Bacteria,2GD9T@200918|Thermotogae	200918|Thermotogae	S	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_6266502_0	679926.Mpet_2150	3.016e-23	112.0	arCOG03264@1|root,arCOG03264@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
XH3_k127_6268074_0	1121468.AUBR01000026_gene2920	1.711e-163	524.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,42FC2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
XH3_k127_6268074_2	1201290.M902_1468	1.249e-55	200.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2MUDA@213481|Bdellovibrionales,2WNCZ@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
XH3_k127_6268074_3	1123371.ATXH01000011_gene65	1.348e-25	111.0	COG0781@1|root,COG0781@2|Bacteria,2GHUU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
XH3_k127_6268074_1	880073.Calab_0215	9.001e-57	206.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
XH3_k127_6342828_1	1408473.JHXO01000008_gene2695	1.084e-37	147.0	arCOG12964@1|root,2Z7HP@2|Bacteria,4P10P@976|Bacteroidetes	976|Bacteroidetes	S	Tocopherol cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Tocopherol_cycl
XH3_k127_6342828_2	1444306.JFZC01000073_gene1800	6.594e-25	110.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,26NV2@186821|Sporolactobacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
XH3_k127_6342828_3	1144319.PMI16_04123	3.597e-18	99.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2VP95@28216|Betaproteobacteria,476IM@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
XH3_k127_6342828_0	269797.Mbar_A3461	1.316e-73	276.0	COG3291@1|root,COG3391@1|root,arCOG02516@1|root,arCOG02550@1|root,arCOG03991@1|root,arCOG02508@2157|Archaea,arCOG02516@2157|Archaea,arCOG02550@2157|Archaea,arCOG02562@2157|Archaea,arCOG03991@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
XH3_k127_6371188_0	1379698.RBG1_1C00001G1656	1.97e-232	744.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
XH3_k127_6371188_1	1232410.KI421418_gene2310	2.173e-70	247.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria,43S2J@69541|Desulfuromonadales	28221|Deltaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
XH3_k127_6383155_0	56780.SYN_00063	4.042e-139	457.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MR5Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
XH3_k127_6383155_1	436114.SYO3AOP1_0296	4.403e-61	212.0	COG0048@1|root,COG0048@2|Bacteria,2G3ZY@200783|Aquificae	200783|Aquificae	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
XH3_k127_6383155_2	266779.Meso_1682	1.386e-56	201.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2TSI8@28211|Alphaproteobacteria,43GWQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
XH3_k127_6402222_0	1519464.HY22_09605	1.361e-43	167.0	2APA7@1|root,31EC9@2|Bacteria,1FFNC@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
XH3_k127_6402222_2	1121012.AUKX01000053_gene2547	4.967e-07	61.0	COG4692@1|root,COG4692@2|Bacteria,4NEYM@976|Bacteroidetes,1IIH8@117743|Flavobacteriia,23G2P@178469|Arenibacter	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
XH3_k127_6402222_1	269797.Mbar_A2783	3.54e-14	83.0	COG3291@1|root,arCOG02515@1|root,arCOG02527@1|root,arCOG02510@2157|Archaea,arCOG02515@2157|Archaea,arCOG02527@2157|Archaea,2Y7RP@28890|Euryarchaeota,2NBKZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF3344,PKD
XH3_k127_6403365_2	518766.Rmar_1150	7.109e-08	57.0	COG3210@1|root,COG3210@2|Bacteria,4PND6@976|Bacteroidetes,1FJRB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_6403365_0	926550.CLDAP_17040	7.218e-121	413.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
XH3_k127_6403365_1	883.DvMF_1147	2.215e-69	242.0	COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,42NEP@68525|delta/epsilon subdivisions,2WPFQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
XH3_k127_6414092_4	1121930.AQXG01000005_gene702	8.184e-05	52.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_C
XH3_k127_6414092_3	907348.TresaDRAFT_1714	3.261e-05	55.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
XH3_k127_6414092_0	580331.Thit_1283	1.327e-126	415.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,42ER1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
XH3_k127_6414092_2	399550.Smar_0375	8.854e-09	62.0	COG2510@1|root,arCOG03426@2157|Archaea,2XS8X@28889|Crenarchaeota	28889|Crenarchaeota	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
XH3_k127_6414092_1	370438.PTH_0628	2.188e-22	102.0	COG0477@1|root,COG2814@2|Bacteria,1UGP8@1239|Firmicutes,24ENP@186801|Clostridia,263QB@186807|Peptococcaceae	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
XH3_k127_6427594_0	1094980.Mpsy_0983	2.835e-59	233.0	COG1404@1|root,arCOG02538@1|root,arCOG03439@1|root,arCOG00702@2157|Archaea,arCOG02538@2157|Archaea,arCOG03439@2157|Archaea,2XTGN@28890|Euryarchaeota,2N9WH@224756|Methanomicrobia	224756|Methanomicrobia	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Calx-beta,Inhibitor_I9,Peptidase_S8
XH3_k127_6427594_2	1379698.RBG1_1C00001G1194	2.101e-09	71.0	COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	3.2.1.91	ko:K14194,ko:K19668	ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CHU_C,DUF11,FlgD_ig,PKD,SdrD_B
XH3_k127_6427594_1	316274.Haur_4643	3.682e-22	107.0	COG1572@1|root,COG1572@2|Bacteria,2G7MU@200795|Chloroflexi,374XB@32061|Chloroflexia	2|Bacteria	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB,Peptidase_M66,fn3
XH3_k127_6427594_3	880071.Fleli_2820	0.0008791	47.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
XH3_k127_6474112_1	373903.Hore_21040	9.326e-12	71.0	2CIJU@1|root,332RU@2|Bacteria,1VESI@1239|Firmicutes,24QR7@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1893)	-	-	-	-	-	-	-	-	-	-	-	-	TM1506
XH3_k127_6474112_0	1120985.AUMI01000014_gene771	9.087e-46	180.0	COG0763@1|root,COG0763@2|Bacteria,1TRP4@1239|Firmicutes,4H22C@909932|Negativicutes	909932|Negativicutes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
XH3_k127_6503163_2	1395516.PMO01_10170	1.265e-08	57.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RYEF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	bphP	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_2,PHY,Response_reg
XH3_k127_6503163_1	321327.CYA_2737	1.209e-20	96.0	COG0745@1|root,COG0745@2|Bacteria,1G10E@1117|Cyanobacteria,1H01R@1129|Synechococcus	1117|Cyanobacteria	T	response regulator	-	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	DUF4388,Response_reg
XH3_k127_6503163_0	1121930.AQXG01000001_gene1230	4.864e-79	287.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
XH3_k127_6529074_1	1347086.CCBA010000046_gene2482	1.135e-33	137.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1ZCZ4@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH3_k127_6529074_0	671143.DAMO_0351	3.315e-53	193.0	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_6537376_2	1267535.KB906767_gene4838	1.065e-05	52.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
XH3_k127_6537376_1	859657.RPSI07_1404	7.544e-19	97.0	COG2020@1|root,COG2020@2|Bacteria,1R47K@1224|Proteobacteria,2VPZR@28216|Betaproteobacteria,1K6ZR@119060|Burkholderiaceae	28216|Betaproteobacteria	O	isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
XH3_k127_6537376_0	1250232.JQNJ01000001_gene2322	1.572e-21	104.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
XH3_k127_655538_4	27289.XP_003670786.1	4.148e-09	57.0	COG0257@1|root,KOG4122@2759|Eukaryota,3A634@33154|Opisthokonta,3P8H9@4751|Fungi,3QZ64@4890|Ascomycota,3RVCR@4891|Saccharomycetes	4751|Fungi	J	Belongs to the bacterial ribosomal protein bL36 family	-	GO:0000313,GO:0000315,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0031974,GO:0032543,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0071840,GO:0098798,GO:0140053,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
XH3_k127_655538_3	439235.Dalk_1893	2.552e-31	123.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MKKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
XH3_k127_655538_1	1121430.JMLG01000033_gene1352	9.673e-85	287.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,260SK@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
XH3_k127_655538_2	667014.Thein_1484	5.905e-69	240.0	COG0563@1|root,COG0563@2|Bacteria,2GGXU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
XH3_k127_655538_0	909663.KI867150_gene79	2.644e-234	734.0	COG4868@1|root,COG4868@2|Bacteria,1NN03@1224|Proteobacteria,42P46@68525|delta/epsilon subdivisions,2WKVV@28221|Deltaproteobacteria,2MR6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
XH3_k127_659288_3	398767.Glov_2781	4.685e-07	54.0	COG1186@1|root,COG1186@2|Bacteria,1NBAD@1224|Proteobacteria,42UTT@68525|delta/epsilon subdivisions,2WQZK@28221|Deltaproteobacteria,43VGU@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
XH3_k127_659288_1	1353537.TP2_08545	1.123e-09	68.0	COG3449@1|root,COG3449@2|Bacteria,1QTW6@1224|Proteobacteria,2V7P2@28211|Alphaproteobacteria,2XN9W@285107|Thioclava	28211|Alphaproteobacteria	L	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
XH3_k127_659288_2	880073.Calab_3215	3.798e-08	65.0	COG0366@1|root,COG0708@1|root,COG0366@2|Bacteria,COG0708@2|Bacteria,2NREA@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 70	-	-	3.1.11.2,3.2.1.1	ko:K01142,ko:K01176	ko00500,ko01100,ko03410,ko04973,map00500,map01100,map03410,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000,ko03400	-	GH13	-	Alpha-amylase,CBM_25,DUF1939,He_PIG
XH3_k127_659288_0	1337936.IJ00_06470	2.116e-33	144.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HIJM@1161|Nostocales	1117|Cyanobacteria	S	SPTR Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
XH3_k127_6601277_3	706587.Desti_4515	2.471e-05	48.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125,ko:K03646	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	Fer4,Fer4_17,Fer4_22,Fer4_8,FrhB_FdhB_C
XH3_k127_6601277_0	1121472.AQWN01000003_gene1534	1.384e-104	351.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
XH3_k127_6601277_2	1379698.RBG1_1C00001G1317	1.092e-08	68.0	COG1361@1|root,COG3391@1|root,COG1361@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
XH3_k127_6601277_1	935948.KE386495_gene1170	5.51e-18	98.0	COG3055@1|root,COG3055@2|Bacteria,1V8SQ@1239|Firmicutes,25BH8@186801|Clostridia	186801|Clostridia	E	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
XH3_k127_6601277_4	945713.IALB_1400	4.69e-05	56.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	rtxA	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	ASH,CBM_2,Calx-beta,DUF4214,FlgD_ig,HemolysinCabind,SdrD_B
XH3_k127_6606296_1	717231.Flexsi_0532	6.86e-107	349.0	COG4799@1|root,COG4799@2|Bacteria,2GEP0@200930|Deferribacteres	200930|Deferribacteres	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
XH3_k127_6606296_0	1304284.L21TH_0800	1.238e-219	696.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,36H9W@31979|Clostridiaceae	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
XH3_k127_6606296_4	1125863.JAFN01000001_gene2899	5.361e-41	154.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
XH3_k127_6606296_2	324602.Caur_0308	3.028e-84	289.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi,37696@32061|Chloroflexia	32061|Chloroflexia	O	PFAM heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
XH3_k127_6606296_5	525904.Tter_2295	0.000123	48.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	hspR	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
XH3_k127_6606296_3	96561.Dole_2647	8.238e-72	245.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2MHUF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH3_k127_6631185_4	1440774.Y900_027930	1.542e-05	50.0	COG0500@1|root,COG2226@2|Bacteria,2GJUF@201174|Actinobacteria,236M1@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
XH3_k127_6631185_3	562983.HMPREF0433_01137	2.635e-12	73.0	COG2020@1|root,COG2020@2|Bacteria,1V7ZM@1239|Firmicutes,4I5W4@91061|Bacilli,3WFHG@539002|Bacillales incertae sedis	91061|Bacilli	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
XH3_k127_6631185_0	1120951.AUBG01000006_gene444	1.691e-31	143.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1HY2V@117743|Flavobacteriia	976|Bacteroidetes	Q	Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
XH3_k127_6631185_2	889378.Spiaf_0517	5.565e-20	106.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
XH3_k127_6631185_1	648996.Theam_0533	4.05e-29	124.0	COG3291@1|root,COG4870@1|root,COG3291@2|Bacteria,COG4870@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
XH3_k127_6686818_2	123214.PERMA_0937	8.611e-12	77.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
XH3_k127_6686818_0	309799.DICTH_0179	3.236e-96	336.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
XH3_k127_6686818_3	880073.Calab_0647	3.994e-08	66.0	COG1361@1|root,COG1595@1|root,COG1361@2|Bacteria,COG1595@2|Bacteria,2NPVV@2323|unclassified Bacteria	2|Bacteria	K	GxGYxYP putative glycoside hydrolase C-terminal domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
XH3_k127_6686818_1	459349.CLOAM0099	2.81e-71	268.0	COG2234@1|root,COG2234@2|Bacteria,2NQ2F@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M28	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
XH3_k127_6688038_4	1089550.ATTH01000001_gene2387	7.076e-12	78.0	COG1747@1|root,COG4797@1|root,COG1747@2|Bacteria,COG4797@2|Bacteria,4NEB8@976|Bacteroidetes,1FJ0K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
XH3_k127_6688038_0	1121422.AUMW01000001_gene2517	1.561e-205	657.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,2604R@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
XH3_k127_6688038_3	886293.Sinac_7456	1.952e-48	184.0	COG0142@1|root,COG0142@2|Bacteria,2IX56@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
XH3_k127_6688038_2	1121456.ATVA01000018_gene350	1.031e-79	276.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,2M9FA@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
XH3_k127_6688038_1	1379698.RBG1_1C00001G0597	1.285e-106	363.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	degQ	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
XH3_k127_6722507_2	56780.SYN_01628	9.852e-16	78.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2MR6S@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
XH3_k127_6722507_0	1123277.KB893244_gene5108	4.51e-89	314.0	COG3188@1|root,COG3188@2|Bacteria,4NHCJ@976|Bacteroidetes,47K9Y@768503|Cytophagia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_6722507_1	1122621.ATZA01000023_gene4240	8.251e-45	173.0	COG0419@1|root,COG3179@1|root,COG0419@2|Bacteria,COG3179@2|Bacteria,4NGQP@976|Bacteroidetes,1IRWD@117747|Sphingobacteriia	976|Bacteroidetes	L	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_6730422_4	1379698.RBG1_1C00001G1833	0.0007204	44.0	COG1379@1|root,COG1379@2|Bacteria,2NNW8@2323|unclassified Bacteria	2|Bacteria	L	DNA helicase	yqxK	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4178,PHP_C,UvrD-helicase,UvrD_C
XH3_k127_6730422_0	1379698.RBG1_1C00001G1833	2.817e-151	488.0	COG1379@1|root,COG1379@2|Bacteria,2NNW8@2323|unclassified Bacteria	2|Bacteria	L	DNA helicase	yqxK	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4178,PHP_C,UvrD-helicase,UvrD_C
XH3_k127_6730422_1	485916.Dtox_1339	1.285e-37	156.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,25E3F@186801|Clostridia,261W3@186807|Peptococcaceae	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
XH3_k127_6730422_2	215803.DB30_7610	1.92e-26	121.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
XH3_k127_6730422_3	246197.MXAN_2932	1.26e-05	52.0	2DFGJ@1|root,2ZRS3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_6753409_1	429009.Adeg_1618	1.097e-53	199.0	COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,2480F@186801|Clostridia,42EW5@68295|Thermoanaerobacterales	186801|Clostridia	K	RNA polymerase sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
XH3_k127_6753409_0	667014.Thein_2111	1.4e-121	402.0	COG3276@1|root,COG3276@2|Bacteria,2GH20@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
XH3_k127_6762574_0	1051632.TPY_3574	4.718e-38	149.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WCGV@538999|Clostridiales incertae sedis	186801|Clostridia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
XH3_k127_6762574_1	273068.TTE0875	2.477e-35	142.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,42G1K@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
XH3_k127_6762574_2	865938.Weevi_1244	3.417e-09	68.0	COG0284@1|root,COG0461@1|root,COG0284@2|Bacteria,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1HXXU@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
XH3_k127_6779611_3	290317.Cpha266_0296	9.898e-17	83.0	COG0474@1|root,COG0474@2|Bacteria	2|Bacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
XH3_k127_6779611_0	521045.Kole_0309	3.514e-117	384.0	COG0330@1|root,COG0330@2|Bacteria,2GC8F@200918|Thermotogae	200918|Thermotogae	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
XH3_k127_6779611_4	331869.BAL199_09008	1.073e-09	65.0	COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,2UC8X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	MA20_06475	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
XH3_k127_6779611_2	671143.DAMO_2617	3.768e-29	124.0	COG1514@1|root,COG1514@2|Bacteria,2NPRT@2323|unclassified Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
XH3_k127_6779611_1	429009.Adeg_0626	7.216e-41	157.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,42F5V@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
XH3_k127_6844580_2	1235800.C819_01670	6.077e-46	174.0	2EXW2@1|root,33R56@2|Bacteria,1VR16@1239|Firmicutes,24IMV@186801|Clostridia	186801|Clostridia	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
XH3_k127_6844580_0	387093.SUN_0313	7.058e-53	192.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2YNVV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	bacterioferritin comigratory protein	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
XH3_k127_6844580_1	1123242.JH636435_gene1911	2.269e-52	190.0	COG0210@1|root,COG0210@2|Bacteria,2IY8S@203682|Planctomycetes	203682|Planctomycetes	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
XH3_k127_6852052_0	882.DVU_3395	2.661e-68	248.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
XH3_k127_6852052_1	926561.KB900617_gene1659	1.368e-24	115.0	COG4206@1|root,COG4206@2|Bacteria,1V287@1239|Firmicutes,24SUD@186801|Clostridia,3WB9E@53433|Halanaerobiales	186801|Clostridia	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
XH3_k127_6899559_3	1191523.MROS_1633	2.399e-11	69.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	ACPS,CBM9_1
XH3_k127_6899559_0	68223.JNZY01000027_gene6961	2.546e-46	173.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria	201174|Actinobacteria	K	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
XH3_k127_6899559_2	1379698.RBG1_1C00001G0099	2.519e-22	110.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
XH3_k127_6899559_1	269797.Mbar_A3441	2.534e-41	159.0	COG0535@1|root,arCOG00938@2157|Archaea,2Y8D5@28890|Euryarchaeota,2NBPE@224756|Methanomicrobia	224756|Methanomicrobia	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
XH3_k127_6916584_0	768670.Calni_1510	6.656e-264	829.0	COG0480@1|root,COG0480@2|Bacteria,2GFAG@200930|Deferribacteres	200930|Deferribacteres	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
XH3_k127_6939960_4	1218103.CIN01S_09_04580	0.0004427	51.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia,3ZQZK@59732|Chryseobacterium	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
XH3_k127_6939960_0	234267.Acid_5970	5.679e-13	79.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,LCAT,PGAP1
XH3_k127_6939960_1	1123277.KB893228_gene2106	7.092e-12	71.0	COG2010@1|root,COG2010@2|Bacteria,4NKWY@976|Bacteroidetes,47UE1@768503|Cytophagia	976|Bacteroidetes	C	Carbohydrate binding module (family 6)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,PSCyt1,PSCyt2,PSD1
XH3_k127_6939960_3	1123508.JH636439_gene678	1.529e-05	52.0	COG2010@1|root,COG2010@2|Bacteria,2IXQE@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
XH3_k127_6939960_2	1123242.JH636435_gene2260	6.073e-07	56.0	COG0454@1|root,COG0456@2|Bacteria,2J4PU@203682|Planctomycetes	203682|Planctomycetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
XH3_k127_6964063_3	935836.JAEL01000007_gene2924	6.274e-05	54.0	COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus	91061|Bacilli	V	Belongs to the UPF0214 family	estB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Peptidase_M6
XH3_k127_6964063_5	945713.IALB_2347	0.0004578	51.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
XH3_k127_6964063_0	1121472.AQWN01000010_gene589	2.256e-113	381.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,26426@186807|Peptococcaceae	186801|Clostridia	C	FAD linked	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
XH3_k127_6964063_1	589865.DaAHT2_1638	2.967e-34	139.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2MKJV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
XH3_k127_6964063_2	443143.GM18_2299	3.305e-17	87.0	COG0640@1|root,COG0640@2|Bacteria,1RGYC@1224|Proteobacteria,42X86@68525|delta/epsilon subdivisions,2WSJA@28221|Deltaproteobacteria,43V43@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
XH3_k127_6964063_4	673862.BABL1_390	0.0002238	52.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
XH3_k127_6978382_1	247490.KSU1_B0579	3.231e-60	219.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,2IZWU@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
XH3_k127_6978382_0	580332.Slit_2828	1.25e-93	327.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VJGY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_9,TarH
XH3_k127_6978382_7	693661.Arcve_0901	1.97e-05	57.0	COG0778@1|root,arCOG00288@2157|Archaea,2XXW2@28890|Euryarchaeota	28890|Euryarchaeota	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
XH3_k127_6978382_4	290512.Paes_0014	8.685e-28	128.0	COG0760@1|root,COG0760@2|Bacteria,1FDC8@1090|Chlorobi	1090|Chlorobi	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N,SurA_N_3
XH3_k127_6978382_5	1536774.H70357_15275	6.173e-13	79.0	COG0760@1|root,COG0760@2|Bacteria,1UZZM@1239|Firmicutes,4HE14@91061|Bacilli,26RHI@186822|Paenibacillaceae	91061|Bacilli	O	peptidyl-prolyl isomerase	yacD	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
XH3_k127_6978382_9	1162668.LFE_2346	0.0002095	53.0	COG0760@1|root,COG0760@2|Bacteria,3J16U@40117|Nitrospirae	40117|Nitrospirae	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
XH3_k127_6978382_6	1110502.TMO_0354	8.172e-13	81.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,2JS3R@204441|Rhodospirillales	204441|Rhodospirillales	M	peptidylprolyl isomerase	ppiC	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
XH3_k127_6978382_8	889378.Spiaf_0474	3.575e-05	53.0	28QN8@1|root,2ZD3W@2|Bacteria,2JBCA@203691|Spirochaetes	203691|Spirochaetes	S	DOMON domain	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_6978382_2	5888.CAK71390	4.895e-30	132.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
XH3_k127_6978382_3	1094980.Mpsy_2668	2.736e-29	122.0	arCOG03042@1|root,arCOG03042@2157|Archaea,2Y7NV@28890|Euryarchaeota,2NAUB@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
XH3_k127_7000753_0	1379698.RBG1_1C00001G1888	8.472e-136	441.0	COG0468@1|root,COG0468@2|Bacteria,2NNYW@2323|unclassified Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
XH3_k127_7000753_1	1537917.JU82_04150	2.962e-20	96.0	COG0352@1|root,COG0352@2|Bacteria,1P3Q4@1224|Proteobacteria,42SIF@68525|delta/epsilon subdivisions,2YPJ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine-phosphate diphosphorylase activity	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	-
XH3_k127_7000753_2	269797.Mbar_A1214	0.0008326	44.0	arCOG03971@1|root,arCOG03971@2157|Archaea	269797.Mbar_A1214|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7013224_2	1499967.BAYZ01000030_gene1187	7.568e-11	68.0	COG2006@1|root,COG2006@2|Bacteria,2NPI6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
XH3_k127_7013224_0	1173027.Mic7113_1218	2.107e-96	329.0	COG4826@1|root,COG4826@2|Bacteria,1G29E@1117|Cyanobacteria,1H9A9@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
XH3_k127_7013224_1	1122182.KB903814_gene2972	7.994e-16	87.0	COG1378@1|root,COG1378@2|Bacteria,2H53C@201174|Actinobacteria	201174|Actinobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
XH3_k127_7024885_1	1247963.JPHU01000003_gene1456	7.267e-09	59.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
XH3_k127_7024885_0	671143.DAMO_0317	1.603e-09	70.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,CBM_35,DUF1080,PKD
XH3_k127_7049542_2	696281.Desru_0798	3.92e-11	66.0	COG5341@1|root,COG5341@2|Bacteria	2|Bacteria	S	NusG domain II	ynhH	-	-	-	-	-	-	-	-	-	-	-	NusG_II
XH3_k127_7049542_0	484770.UFO1_2948	4.937e-23	113.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,4H51B@909932|Negativicutes	909932|Negativicutes	S	Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
XH3_k127_7049542_1	202752.JL53_13930	5.471e-16	91.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,26IXZ@186820|Listeriaceae	91061|Bacilli	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
XH3_k127_7064281_0	1463921.JODF01000049_gene5625	5.905e-05	56.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
XH3_k127_7074571_2	1125863.JAFN01000001_gene1387	4.873e-29	119.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42N28@68525|delta/epsilon subdivisions,2WJVR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	hemU	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
XH3_k127_7074571_0	555088.DealDRAFT_0687	1.165e-62	226.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,42JZH@68298|Syntrophomonadaceae	186801|Clostridia	P	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
XH3_k127_7074571_1	632245.CLP_3571	6.579e-62	217.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,36ET7@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
XH3_k127_7149589_3	1379698.RBG1_1C00001G1789	9.009e-25	116.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
XH3_k127_7149589_0	1379698.RBG1_1C00001G0340	9.787e-146	498.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
XH3_k127_7149589_2	70601.3256621	8.687e-47	183.0	COG1446@1|root,arCOG04779@2157|Archaea,2XTTT@28890|Euryarchaeota,2435B@183968|Thermococci	183968|Thermococci	E	asparaginase activity	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
XH3_k127_7149589_1	767817.Desgi_1638	3.195e-63	226.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,260YT@186807|Peptococcaceae	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
XH3_k127_7149589_4	1198114.AciX9_1119	1.787e-15	83.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
XH3_k127_7171374_0	1268237.G114_09940	3.816e-57	210.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1NAY1@1224|Proteobacteria,1RP74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.178	ko:K11392	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
XH3_k127_7171374_3	1089550.ATTH01000001_gene1368	0.0005426	49.0	COG3270@1|root,COG3270@2|Bacteria	2|Bacteria	J	rRNA methyltransferase activity	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.178	ko:K11392	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
XH3_k127_7171374_1	1313304.CALK_0488	5.079e-54	197.0	COG0566@1|root,COG0566@2|Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase
XH3_k127_7171374_2	742726.HMPREF9448_00924	2.257e-27	123.0	COG0235@1|root,COG0235@2|Bacteria,4NIQK@976|Bacteroidetes,2FN5U@200643|Bacteroidia,22WSD@171551|Porphyromonadaceae	976|Bacteroidetes	G	Class II Aldolase and Adducin N-terminal domain	rhaD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
XH3_k127_7172336_0	1267535.KB906767_gene929	8.992e-113	385.0	COG0488@1|root,COG0488@2|Bacteria,3Y340@57723|Acidobacteria,2JI2P@204432|Acidobacteriia	204432|Acidobacteriia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
XH3_k127_7172336_1	1047013.AQSP01000122_gene2257	1.629e-34	136.0	COG1186@1|root,COG1186@2|Bacteria	2|Bacteria	J	translation release factor activity	prfA3	-	-	-	-	-	-	-	-	-	-	-	RF-1
XH3_k127_7192840_0	653733.Selin_2242	1.23e-129	422.0	COG0057@1|root,COG0057@2|Bacteria	2|Bacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
XH3_k127_7192840_1	518766.Rmar_1800	1.935e-106	355.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1FITC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
XH3_k127_720697_2	1408813.AYMG01000028_gene2515	5.102e-05	52.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1IRAV@117747|Sphingobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_720697_1	459349.CLOAM1068	1.767e-44	172.0	COG2426@1|root,COG2426@2|Bacteria,2NRIQ@2323|unclassified Bacteria	2|Bacteria	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
XH3_k127_720697_0	521011.Mpal_1968	4.169e-70	250.0	COG0648@1|root,arCOG01894@2157|Archaea,2XV5I@28890|Euryarchaeota	28890|Euryarchaeota	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
XH3_k127_7210137_0	945713.IALB_2930	5.951e-12	72.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7246042_1	351160.RCIX2472	1.663e-17	83.0	COG4802@1|root,arCOG01100@2157|Archaea,2Y3RU@28890|Euryarchaeota,2NATY@224756|Methanomicrobia	224756|Methanomicrobia	C	Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
XH3_k127_7246042_0	477974.Daud_2069	7.83e-21	94.0	COG0011@1|root,COG0011@2|Bacteria,1VAIR@1239|Firmicutes,24NBA@186801|Clostridia,262QE@186807|Peptococcaceae	186801|Clostridia	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
XH3_k127_7246042_3	1380394.JADL01000005_gene5464	9.837e-06	56.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,2JUNY@204441|Rhodospirillales	204441|Rhodospirillales	K	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
XH3_k127_7246042_2	1519464.HY22_04580	8.024e-16	86.0	2CBA8@1|root,30BZT@2|Bacteria,1FEGZ@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7281550_1	237368.SCABRO_03012	9.852e-56	204.0	2ANS9@1|root,31DS7@2|Bacteria,2IZX5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7281550_0	671143.DAMO_0350	5.907e-72	252.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7281550_2	247490.KSU1_B0649	2.546e-24	104.0	29ZH8@1|root,30MGZ@2|Bacteria,2J0G3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7290594_0	368407.Memar_1722	2.239e-109	363.0	COG4294@1|root,arCOG01898@2157|Archaea,2XVT2@28890|Euryarchaeota	28890|Euryarchaeota	L	UV-endonuclease UvdE	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
XH3_k127_7290594_1	660470.Theba_0505	7.498e-53	191.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,2GE26@200918|Thermotogae	200918|Thermotogae	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
XH3_k127_7413683_1	1242864.D187_006458	3.182e-17	89.0	COG0457@1|root,COG0457@2|Bacteria,1PYTB@1224|Proteobacteria,42VYS@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_16,TPR_2,TPR_6,TPR_8
XH3_k127_7413683_0	1191523.MROS_0394	2.45e-38	158.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_0394|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7447129_3	886293.Sinac_7569	1.235e-28	124.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
XH3_k127_7447129_2	439235.Dalk_5269	5.01e-29	134.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R09K@1224|Proteobacteria	1224|Proteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2
XH3_k127_7447129_1	404380.Gbem_1114	9.341e-43	177.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
XH3_k127_7447129_0	335543.Sfum_1309	8.793e-90	308.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2MQT7@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Aldehyde dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
XH3_k127_7469848_1	215803.DB30_7610	9.078e-126	421.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
XH3_k127_7469848_3	1499967.BAYZ01000045_gene2673	1.285e-59	224.0	COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
XH3_k127_7469848_2	515635.Dtur_1285	1.365e-111	376.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
XH3_k127_7469848_0	215803.DB30_7610	2.895e-131	449.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
XH3_k127_7470876_0	945713.IALB_0147	1.064e-25	124.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
XH3_k127_7470876_1	35754.JNYJ01000064_gene1394	6.218e-07	63.0	COG1404@1|root,COG2133@1|root,COG3291@1|root,COG4782@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4782@2|Bacteria,2GJFY@201174|Actinobacteria,4DASA@85008|Micromonosporales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CarboxypepD_reg,F5_F8_type_C,GSDH,PA14,PKD
XH3_k127_7492036_3	1449126.JQKL01000006_gene824	6.038e-18	85.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia	186801|Clostridia	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
XH3_k127_7492036_2	1343740.M271_20215	3.989e-21	107.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
XH3_k127_7492036_0	497321.C664_17300	6.352e-181	578.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,2VNTF@28216|Betaproteobacteria,2KVB8@206389|Rhodocyclales	206389|Rhodocyclales	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
XH3_k127_7492036_4	382464.ABSI01000011_gene2315	2.872e-17	89.0	COG0526@1|root,COG0526@2|Bacteria,46W21@74201|Verrucomicrobia	74201|Verrucomicrobia	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
XH3_k127_7492036_1	398767.Glov_1186	3.066e-51	190.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
XH3_k127_7492036_5	706587.Desti_5397	1.341e-09	66.0	COG0640@1|root,COG0640@2|Bacteria,1N19R@1224|Proteobacteria,42TRS@68525|delta/epsilon subdivisions,2WQHU@28221|Deltaproteobacteria,2MSJR@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
XH3_k127_7522227_0	1089550.ATTH01000001_gene2273	3.182e-38	166.0	COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,1FJ4S@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_753129_0	33178.CADATEAP00005729	5.922e-07	63.0	KOG4441@1|root,KOG4441@2759|Eukaryota,3A0E3@33154|Opisthokonta,3Q4WW@4751|Fungi,3RN8F@4890|Ascomycota	4751|Fungi	T	Kelch	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
XH3_k127_7532079_1	511051.CSE_02560	2.314e-53	194.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Nitroreductase
XH3_k127_7532079_4	862517.HMPREF9225_1436	5.922e-09	64.0	COG3086@1|root,COG3086@2|Bacteria,1VECS@1239|Firmicutes,25NDG@186801|Clostridia,22I1F@1570339|Peptoniphilaceae	186801|Clostridia	T	Positive regulator of sigma(E), RseC MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
XH3_k127_7532079_0	1047013.AQSP01000130_gene1849	2.909e-73	257.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	pdxH	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
XH3_k127_7532079_2	457570.Nther_1894	2.571e-46	174.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
XH3_k127_7532079_3	661478.OP10G_4062	4.134e-30	128.0	COG0482@1|root,COG0482@2|Bacteria	2|Bacteria	J	sulfurtransferase activity	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
XH3_k127_7560735_2	518766.Rmar_1780	1.066e-89	306.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1FIPW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
XH3_k127_7560735_4	1340493.JNIF01000003_gene2587	1.85e-69	249.0	COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria	57723|Acidobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
XH3_k127_7560735_3	56780.SYN_00244	6.599e-81	292.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria,2MQ4K@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
XH3_k127_7560735_5	518766.Rmar_1777	1.63e-42	167.0	COG1566@1|root,COG1566@2|Bacteria,4PKPZ@976|Bacteroidetes	976|Bacteroidetes	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
XH3_k127_7560735_7	857293.CAAU_1247	1.787e-18	87.0	COG0298@1|root,COG0298@2|Bacteria,1VFE0@1239|Firmicutes,24UXU@186801|Clostridia,36NYN@31979|Clostridiaceae	186801|Clostridia	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
XH3_k127_7560735_0	880073.Calab_1878	1.072e-160	517.0	2CD20@1|root,2Z7SQ@2|Bacteria,2NNUF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7560735_1	264732.Moth_2117	3.663e-102	341.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,42FNN@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Aspartate glutamate uridylate kinase	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
XH3_k127_7560735_8	313625.BL107_05759	0.0001259	47.0	2DSJE@1|root,33GEB@2|Bacteria,1GB2T@1117|Cyanobacteria,1H160@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7560735_6	1249627.D779_2994	1.034e-19	100.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,1WZZW@135613|Chromatiales	135613|Chromatiales	P	TonB dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
XH3_k127_7570398_1	1122223.KB890701_gene2325	2.911e-89	308.0	COG2805@1|root,COG2805@2|Bacteria,1WIJD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Tfp pilus assembly protein pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
XH3_k127_7570398_3	555088.DealDRAFT_2310	3.243e-29	122.0	COG1150@1|root,COG1150@2|Bacteria,1V8UM@1239|Firmicutes,24J4U@186801|Clostridia,42K4E@68298|Syntrophomonadaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
XH3_k127_7570398_2	97139.C824_04335	5.361e-78	270.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,36QTR@31979|Clostridiaceae	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
XH3_k127_7570398_0	1449126.JQKL01000012_gene3470	4.048e-239	755.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,Pyr_redox_2
XH3_k127_7570398_4	349161.Dred_1327	1.066e-27	113.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
XH3_k127_7578617_6	429009.Adeg_1661	9.559e-17	82.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,42GW9@68295|Thermoanaerobacterales	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
XH3_k127_7578617_4	102129.Lepto7375DRAFT_4432	4.8e-44	175.0	COG2385@1|root,COG2385@2|Bacteria,1G2FP@1117|Cyanobacteria,1H8UJ@1150|Oscillatoriales	1117|Cyanobacteria	D	PFAM Stage II sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
XH3_k127_7578617_2	1267533.KB906736_gene1109	9.701e-74	254.0	COG1945@1|root,COG1945@2|Bacteria,3Y3KR@57723|Acidobacteria,2JIBD@204432|Acidobacteriia	204432|Acidobacteriia	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	-	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
XH3_k127_7578617_5	706587.Desti_1467	3.104e-20	95.0	COG2164@1|root,COG2164@2|Bacteria,1N81P@1224|Proteobacteria,430JJ@68525|delta/epsilon subdivisions,2WVQQ@28221|Deltaproteobacteria,2MRZH@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
XH3_k127_7578617_3	338966.Ppro_3011	3.491e-54	199.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,43CDX@68525|delta/epsilon subdivisions,2X7PU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
XH3_k127_7578617_0	857087.Metme_3901	4.304e-106	384.0	COG2202@1|root,COG4251@1|root,COG5278@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5278@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2K7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd
XH3_k127_7578617_1	1173029.JH980292_gene633	3.898e-75	282.0	COG5002@1|root,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1H8X5@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
XH3_k127_7614904_4	926550.CLDAP_02300	0.0001369	51.0	COG5617@1|root,COG5617@2|Bacteria,2G8CQ@200795|Chloroflexi	200795|Chloroflexi	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7614904_2	258594.RPA3572	1.702e-27	128.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,2TUYH@28211|Alphaproteobacteria,3JSAB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7614904_1	535289.Dtpsy_2114	1.132e-33	141.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2VPMR@28216|Betaproteobacteria,4AE2C@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
XH3_k127_7614904_0	378806.STAUR_5433	1.667e-39	159.0	COG4965@1|root,COG4965@2|Bacteria,1MYNG@1224|Proteobacteria,42UK9@68525|delta/epsilon subdivisions,2WQT2@28221|Deltaproteobacteria,2YVV9@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
XH3_k127_7614904_3	326427.Cagg_3210	5.969e-20	91.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,374Z4@32061|Chloroflexia	32061|Chloroflexia	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
XH3_k127_7626658_1	1379698.RBG1_1C00001G0527	2.2e-60	211.0	COG1960@1|root,COG1960@2|Bacteria,2NNXA@2323|unclassified Bacteria	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH3_k127_7626658_0	1121413.JMKT01000008_gene1132	1.029e-64	236.0	COG1145@1|root,COG2006@1|root,COG1145@2|Bacteria,COG2006@2|Bacteria,1RABP@1224|Proteobacteria,42QQA@68525|delta/epsilon subdivisions,2WMRX@28221|Deltaproteobacteria,2MG5Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
XH3_k127_7626658_2	243233.MCA3092	1.55e-12	69.0	COG1573@1|root,COG1573@2|Bacteria,1QJIF@1224|Proteobacteria,1THIQ@1236|Gammaproteobacteria,1XEAT@135618|Methylococcales	135618|Methylococcales	L	uracil-DNA	-	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
XH3_k127_7664100_5	1121438.JNJA01000019_gene2804	9.158e-10	64.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MB2G@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
XH3_k127_7664100_0	1391646.AVSU01000045_gene1491	2.838e-104	347.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,25QGP@186804|Peptostreptococcaceae	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
XH3_k127_7664100_3	1379698.RBG1_1C00001G0172	4.359e-31	132.0	COG1825@1|root,COG1825@2|Bacteria,2NPVU@2323|unclassified Bacteria	2|Bacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
XH3_k127_7664100_2	867903.ThesuDRAFT_00412	5.655e-44	169.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3WCIX@538999|Clostridiales incertae sedis	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
XH3_k127_7664100_1	720554.Clocl_2634	1.381e-87	301.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3WG9I@541000|Ruminococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
XH3_k127_7664100_6	720554.Clocl_4134	1.735e-09	64.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3WKNW@541000|Ruminococcaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
XH3_k127_7664100_4	1229780.BN381_100142	1.023e-26	116.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,3UWQD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Single-strand binding protein family	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
XH3_k127_7664100_8	561229.Dd1591_2639	0.0005505	50.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1S5A7@1236|Gammaproteobacteria,2JE99@204037|Dickeya	1236|Gammaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
XH3_k127_7664100_7	1121104.AQXH01000005_gene164	1.16e-08	67.0	COG1404@1|root,COG5276@1|root,COG1404@2|Bacteria,COG5276@2|Bacteria,4PPJ4@976|Bacteroidetes,1IZ3E@117747|Sphingobacteriia	2|Bacteria	O	Protein conserved in bacteria	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FG-GAP,LVIVD,Peptidase_S8,Phytase-like,SLH,TSP_3
XH3_k127_7664100_9	1453500.AT05_09470	0.0008398	51.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes,1I0GI@117743|Flavobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
XH3_k127_76744_3	335543.Sfum_1971	6.422e-09	61.0	COG1150@1|root,COG1150@2|Bacteria,1QWNB@1224|Proteobacteria,43BTA@68525|delta/epsilon subdivisions,2X741@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
XH3_k127_76744_1	1449126.JQKL01000011_gene3547	2.982e-74	261.0	COG4656@1|root,COG4656@2|Bacteria,1UIC8@1239|Firmicutes,25EHB@186801|Clostridia	186801|Clostridia	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,FrhB_FdhB_C
XH3_k127_76744_2	767817.Desgi_2045	2.938e-65	226.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,261SC@186807|Peptococcaceae	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
XH3_k127_76744_0	1499967.BAYZ01000171_gene5567	8.191e-107	356.0	COG1148@1|root,COG4231@1|root,COG1148@2|Bacteria,COG4231@2|Bacteria	2|Bacteria	C	indolepyruvate ferredoxin oxidoreductase activity	bamE	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored,Fer4,Fer4_20,Fer4_7,Pyr_redox_2
XH3_k127_7693226_0	335543.Sfum_3773	4.039e-140	457.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42MQJ@68525|delta/epsilon subdivisions,2WJIX@28221|Deltaproteobacteria,2MR3H@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
XH3_k127_7693226_5	1304880.JAGB01000003_gene1115	6.762e-38	154.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
XH3_k127_7693226_4	909663.KI867150_gene2906	3.131e-41	158.0	COG5423@1|root,COG5423@2|Bacteria,1QP40@1224|Proteobacteria,4377T@68525|delta/epsilon subdivisions,2X9VH@28221|Deltaproteobacteria,2MS6N@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
XH3_k127_7693226_3	1395587.P364_0111735	3.289e-46	177.0	COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,26QMB@186822|Paenibacillaceae	91061|Bacilli	S	haloacid dehalogenase	ysaA	-	3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
XH3_k127_7693226_1	1499967.BAYZ01000002_gene5899	1.259e-117	388.0	COG0505@1|root,COG0505@2|Bacteria,2NNMS@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
XH3_k127_7693226_2	1121129.KB903360_gene3400	6.65e-112	368.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia,22W4Y@171551|Porphyromonadaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase (glutamine-hydrolyzing)	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
XH3_k127_7741582_1	272562.CA_C0203	9.257e-27	115.0	COG0716@1|root,COG0716@2|Bacteria,1V72U@1239|Firmicutes,24JNK@186801|Clostridia,36IZ8@31979|Clostridiaceae	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3,Flavodoxin_5
XH3_k127_7741582_0	398512.JQKC01000004_gene5249	5.152e-166	554.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,3WI29@541000|Ruminococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
XH3_k127_7749039_4	330214.NIDE2490	1.161e-36	144.0	29ZH8@1|root,30MGZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7749039_1	671143.DAMO_0348	1.607e-96	331.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7749039_5	391623.TERMP_00879	1.51e-27	114.0	COG1694@1|root,arCOG01084@2157|Archaea,2XZ0S@28890|Euryarchaeota,244B1@183968|Thermococci	183968|Thermococci	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
XH3_k127_7749039_3	926566.Terro_0882	2.347e-46	181.0	COG0611@1|root,COG0611@2|Bacteria,3Y30U@57723|Acidobacteria,2JHT0@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
XH3_k127_7749039_2	938288.HG326224_gene1650	5.756e-51	184.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,268VT@186813|unclassified Clostridiales	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
XH3_k127_7749039_6	1232443.BAIA02000013_gene3361	1.535e-19	104.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,267Y1@186813|unclassified Clostridiales	186801|Clostridia	F	Anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
XH3_k127_7749039_0	644282.Deba_0697	4.993e-307	961.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	TIGRFAM anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	NRDD
XH3_k127_7749039_7	272123.Anacy_1385	9.45e-13	70.0	COG1872@1|root,COG1872@2|Bacteria,1G935@1117|Cyanobacteria,1HPRR@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
XH3_k127_7759037_1	391625.PPSIR1_31753	5.389e-21	104.0	2DQMB@1|root,337KD@2|Bacteria,1NKJH@1224|Proteobacteria,42X0X@68525|delta/epsilon subdivisions,2WSJT@28221|Deltaproteobacteria,2YVNT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7759037_0	1379698.RBG1_1C00001G1775	2.613e-96	325.0	COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria	2|Bacteria	NU	von Willebrand factor (vWF) type A domain	batA	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
XH3_k127_7772213_1	700598.Niako_2537	7.351e-41	154.0	COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,1IYYX@117747|Sphingobacteriia	976|Bacteroidetes	G	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
XH3_k127_7772213_2	720554.Clocl_2584	3.286e-21	95.0	2E5UQ@1|root,330IY@2|Bacteria,1VI50@1239|Firmicutes,24QVH@186801|Clostridia,3WM0Y@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7772213_3	1047013.AQSP01000016_gene512	2.335e-17	83.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Nitroreductase
XH3_k127_7775100_0	1095769.CAHF01000001_gene3534	3.363e-102	338.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,473SS@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
XH3_k127_7775100_1	1121440.AUMA01000003_gene2990	7.8e-33	133.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2M8KC@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
XH3_k127_7775100_2	1191523.MROS_1863	2.71e-31	130.0	COG0359@1|root,COG0359@2|Bacteria	2|Bacteria	J	rRNA binding	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
XH3_k127_7775100_3	1499967.BAYZ01000179_gene4639	3.906e-16	80.0	COG0238@1|root,COG0238@2|Bacteria,2NPTU@2323|unclassified Bacteria	2|Bacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
XH3_k127_7810148_0	1121285.AUFK01000013_gene2403	2.719e-50	197.0	COG1680@1|root,COG1680@2|Bacteria,4NGXR@976|Bacteroidetes,1HXN3@117743|Flavobacteriia,3ZRAT@59732|Chryseobacterium	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
XH3_k127_7810148_1	1123228.AUIH01000092_gene552	1.418e-16	92.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7817479_0	1246995.AFR_25575	1.875e-97	332.0	COG1835@1|root,COG1835@2|Bacteria,2GN56@201174|Actinobacteria,4DC3S@85008|Micromonosporales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
XH3_k127_7817479_1	1242864.D187_006823	2.579e-06	58.0	COG2319@1|root,COG2834@1|root,COG2319@2|Bacteria,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	-	-	-	-	-	-	-	-	-	LolA
XH3_k127_7817479_2	1123277.KB893198_gene6353	1.132e-05	51.0	COG1629@1|root,COG4771@2|Bacteria,4NFAM@976|Bacteroidetes,47YB8@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
XH3_k127_7820339_1	595460.RRSWK_07188	4.215e-52	207.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	HEAT_2,Peptidase_M9,Peptidase_M9_N
XH3_k127_7820339_0	926560.KE387025_gene4131	3.46e-71	250.0	COG1028@1|root,COG1028@2|Bacteria,1WM2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
XH3_k127_7820339_2	1188235.MBVG_3880	6.341e-27	111.0	COG2314@1|root,COG2314@2|Bacteria,3WU5Y@544448|Tenericutes	544448|Tenericutes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
XH3_k127_7820339_3	45351.EDO28955	2.196e-05	55.0	COG0457@1|root,KOG0548@2759|Eukaryota,38GAN@33154|Opisthokonta,3BEXQ@33208|Metazoa	33208|Metazoa	O	regulation of mitotic cell cycle	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,DED,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8
XH3_k127_7828357_0	555088.DealDRAFT_2355	3.956e-91	316.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,42JMZ@68298|Syntrophomonadaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
XH3_k127_7828357_1	568816.Acin_1506	3.097e-45	173.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4H3ZW@909932|Negativicutes	909932|Negativicutes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
XH3_k127_7828357_2	644966.Tmar_0912	1.896e-40	158.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WCKI@538999|Clostridiales incertae sedis	186801|Clostridia	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
XH3_k127_7834922_7	38833.XP_003062342.1	3.535e-08	57.0	COG0228@1|root,KOG3419@2759|Eukaryota,37UTU@33090|Viridiplantae	33090|Viridiplantae	J	Ribosomal protein S16	-	GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009536,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032543,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:0140053,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
XH3_k127_7834922_6	1120973.AQXL01000131_gene2099	1.23e-17	86.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4IGIJ@91061|Bacilli,27AEB@186823|Alicyclobacillaceae	91061|Bacilli	S	KH domain	-	-	-	-	-	-	-	-	-	-	-	-	KH_4
XH3_k127_7834922_2	309799.DICTH_1424	8.136e-81	276.0	COG0336@1|root,COG0336@2|Bacteria	2|Bacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA_m1G_MT
XH3_k127_7834922_4	1336234.JAGN01000030_gene1504	1.785e-33	133.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,27GF0@186828|Carnobacteriaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
XH3_k127_7834922_3	1120985.AUMI01000019_gene2276	3.211e-59	212.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4H3YJ@909932|Negativicutes	909932|Negativicutes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
XH3_k127_7834922_5	529884.Rhola_00005160	2.066e-23	105.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4FPTI@85023|Microbacteriaceae	201174|Actinobacteria	L	nucleic acid phosphodiester bond hydrolysis	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
XH3_k127_7834922_0	243231.GSU0489	3.552e-189	607.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,43SC2@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM magnesium chelatase ChlI subunit	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
XH3_k127_7834922_1	1519464.HY22_07620	8.8e-141	456.0	COG0677@1|root,COG0677@2|Bacteria,1FEH1@1090|Chlorobi	1090|Chlorobi	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
XH3_k127_7839090_3	1009370.ALO_14337	3.725e-22	99.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4H538@909932|Negativicutes	909932|Negativicutes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
XH3_k127_7839090_0	469617.FUAG_00561	3.518e-56	207.0	COG0130@1|root,COG0130@2|Bacteria,378NK@32066|Fusobacteria	32066|Fusobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
XH3_k127_7839090_2	518766.Rmar_1312	2.03e-50	191.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1FIRP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
XH3_k127_7839090_1	1121918.ARWE01000001_gene3170	7.139e-55	210.0	COG1520@1|root,COG4886@1|root,COG1520@2|Bacteria,COG4886@2|Bacteria,1PIDG@1224|Proteobacteria,42UM6@68525|delta/epsilon subdivisions,2WPZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
XH3_k127_7839090_4	1379698.RBG1_1C00001G1362	1.689e-16	88.0	2A6YD@1|root,30VTC@2|Bacteria,2NQ0X@2323|unclassified Bacteria	2|Bacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
XH3_k127_7839090_5	747365.Thena_1133	2.215e-06	59.0	COG1538@1|root,COG1538@2|Bacteria,1TRDS@1239|Firmicutes	1239|Firmicutes	MU	outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
XH3_k127_7841024_4	880071.Fleli_2447	0.0001785	54.0	COG2203@1|root,COG2208@1|root,COG3292@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3292@2|Bacteria,4NK8Q@976|Bacteroidetes,47YH5@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HisKA_2,Reg_prop,SpoIIE,Y_Y_Y
XH3_k127_7841024_0	1499967.BAYZ01000088_gene5058	3.265e-117	395.0	COG0348@1|root,COG1143@1|root,COG1148@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1148@2|Bacteria,2NP1X@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S binding domain	napF	-	-	ko:K02572	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_5,Fer4_6,Fer4_7
XH3_k127_7841024_1	1499967.BAYZ01000088_gene5057	1.185e-80	278.0	COG2006@1|root,COG2006@2|Bacteria,2NPBD@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
XH3_k127_7841024_3	1089550.ATTH01000001_gene1103	3.094e-08	61.0	COG3210@1|root,COG3386@1|root,COG3420@1|root,COG4412@1|root,COG3210@2|Bacteria,COG3386@2|Bacteria,COG3420@2|Bacteria,COG4412@2|Bacteria,4PEZ5@976|Bacteroidetes,1FJW1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,Laminin_G_3
XH3_k127_7851535_1	1379698.RBG1_1C00001G1092	1.158e-69	259.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
XH3_k127_7851535_2	468556.AQYG01000040_gene1976	0.0004664	51.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4GB4T@85026|Gordoniaceae	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
XH3_k127_7851535_0	1379698.RBG1_1C00001G0378	1.922e-81	279.0	COG0150@1|root,COG0150@2|Bacteria,2NNUJ@2323|unclassified Bacteria	2|Bacteria	F	AIR synthase related protein, N-terminal domain	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1,6.3.4.13	ko:K01933,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844,iECSF_1327.ECSF_2340	AIRS,AIRS_C
XH3_k127_7860935_1	1210884.HG799466_gene12831	2.823e-05	53.0	COG1520@1|root,COG1520@2|Bacteria,2IYTM@203682|Planctomycetes	203682|Planctomycetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_7860935_0	1379698.RBG1_1C00001G1816	4.058e-59	229.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
XH3_k127_7860935_2	1408433.JHXV01000041_gene3573	0.0005446	45.0	COG1770@1|root,COG1770@2|Bacteria	2|Bacteria	E	oligopeptidase activity	-	-	3.4.14.5,3.4.21.26	ko:K01278,ko:K01322	ko04614,ko04974,map04614,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_S9,Peptidase_S9_N
XH3_k127_7907268_2	543913.D521_0291	6.466e-07	52.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,1KQEI@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
XH3_k127_7907268_0	1121468.AUBR01000026_gene2913	1.087e-109	361.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,42FSM@68295|Thermoanaerobacterales	186801|Clostridia	I	dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
XH3_k127_7907268_1	639030.JHVA01000001_gene2762	1.468e-27	117.0	COG0328@1|root,COG0328@2|Bacteria,3Y4EY@57723|Acidobacteria,2JJ1U@204432|Acidobacteriia	204432|Acidobacteriia	L	Reverse transcriptase-like	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
XH3_k127_7946057_0	926550.CLDAP_40290	2.599e-128	416.0	COG0399@1|root,COG0399@2|Bacteria,2G7XI@200795|Chloroflexi	200795|Chloroflexi	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
XH3_k127_7946057_1	63737.Npun_F1380	1.563e-64	230.0	COG2148@1|root,COG2148@2|Bacteria,1GDNT@1117|Cyanobacteria	1117|Cyanobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
XH3_k127_7946057_2	1444770.AF72_03095	8.485e-06	58.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1RKGT@1224|Proteobacteria,1S6ZQ@1236|Gammaproteobacteria,1X563@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the ompA family	mopB	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
XH3_k127_7977386_0	1121447.JONL01000001_gene1002	7.738e-44	163.0	COG1853@1|root,COG1853@2|Bacteria,1RBSR@1224|Proteobacteria,42R0G@68525|delta/epsilon subdivisions,2WMYE@28221|Deltaproteobacteria,2MAM7@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM flavin reductase domain protein FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
XH3_k127_7977386_1	406552.NJ7G_4182	5.349e-07	59.0	COG0454@1|root,arCOG00845@2157|Archaea,2XTIN@28890|Euryarchaeota,23TT3@183963|Halobacteria	183963|Halobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
XH3_k127_7998087_1	247490.KSU1_C0503	8.521e-35	139.0	COG0407@1|root,COG0407@2|Bacteria,2IXZG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,URO-D
XH3_k127_7998087_0	247490.KSU1_C0461	1.819e-59	217.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,2J22H@203682|Planctomycetes	203682|Planctomycetes	EI	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
XH3_k127_7998087_2	1273103.NM10_00809	2.284e-25	106.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H2VM@909932|Negativicutes	909932|Negativicutes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
XH3_k127_8055672_0	1170562.Cal6303_0854	4.829e-149	486.0	COG1132@1|root,COG1132@2|Bacteria,1G0C0@1117|Cyanobacteria,1HJ8H@1161|Nostocales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
XH3_k127_8096578_5	941449.dsx2_0089	6.8e-07	58.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2X2GQ@28221|Deltaproteobacteria,2MC2F@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
XH3_k127_8096578_4	592028.GCWU000321_01822	2.787e-10	67.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4H4TH@909932|Negativicutes	909932|Negativicutes	D	DivIVA domain protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
XH3_k127_8096578_0	1379698.RBG1_1C00001G0102	4.117e-111	364.0	COG0005@1|root,COG0005@2|Bacteria,2NP5F@2323|unclassified Bacteria	2|Bacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
XH3_k127_8096578_3	1121957.ATVL01000008_gene4232	2.882e-13	81.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,47MWE@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
XH3_k127_8096578_1	526227.Mesil_0752	8.117e-42	169.0	COG1057@1|root,COG1057@2|Bacteria,1WJ70@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
XH3_k127_8096578_2	863365.XHC_2719	3.199e-15	82.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1X7J1@135614|Xanthomonadales	135614|Xanthomonadales	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
XH3_k127_8115886_2	880072.Desac_0600	2.886e-29	118.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2MQC4@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
XH3_k127_8115886_0	555079.Toce_0950	3.515e-85	303.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
XH3_k127_8115886_1	330214.NIDE0760	1.627e-60	224.0	COG0772@1|root,COG0772@2|Bacteria,3J0M8@40117|Nitrospirae	40117|Nitrospirae	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
XH3_k127_8181868_0	888059.HMPREF9071_2024	3.202e-07	63.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia,1EQ2Q@1016|Capnocytophaga	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
XH3_k127_8181868_1	1124982.MSI_02000	0.0007587	49.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
XH3_k127_8216598_1	1150600.ADIARSV_1145	0.0007031	47.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1IQV1@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
XH3_k127_8216598_0	1379698.RBG1_1C00001G1364	4.893e-62	227.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
XH3_k127_8218172_5	443144.GM21_3879	1.133e-32	138.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,43S0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
XH3_k127_8218172_3	247490.KSU1_C0311	3.79e-88	302.0	COG3869@1|root,COG3869@2|Bacteria,2IXJG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
XH3_k127_8218172_6	583355.Caka_1064	1.254e-27	117.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia,3K823@414999|Opitutae	414999|Opitutae	S	UvrB/uvrC motif	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
XH3_k127_8218172_4	595494.Tola_2239	4.851e-67	237.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1Y3RG@135624|Aeromonadales	135624|Aeromonadales	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
XH3_k127_8218172_2	1125863.JAFN01000001_gene3405	5.658e-95	326.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
XH3_k127_8218172_0	1379698.RBG1_1C00001G0450	3.314e-158	515.0	COG1190@1|root,COG1190@2|Bacteria,2NNMH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.6	ko:K04567,ko:K04568	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03012,ko03016	-	-	iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJN678.lysS,iJO1366.b4129,iWFL_1372.ECW_m4490	DUF2156,tRNA-synt_2,tRNA-synt_2_TM,tRNA_anti-codon
XH3_k127_8218172_1	498848.TaqDRAFT_3081	7.355e-110	361.0	COG0542@1|root,COG0542@2|Bacteria,1WIQM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
XH3_k127_8234900_0	1121918.ARWE01000001_gene3170	4.55e-36	157.0	COG1520@1|root,COG4886@1|root,COG1520@2|Bacteria,COG4886@2|Bacteria,1PIDG@1224|Proteobacteria,42UM6@68525|delta/epsilon subdivisions,2WPZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
XH3_k127_8255003_2	504472.Slin_5991	4.104e-06	59.0	COG1404@1|root,COG1404@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8,fn3
XH3_k127_8255003_5	236814.IX39_06050	0.0008571	51.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,IgGFc_binding,LTD,PKD,SLH,fn3
XH3_k127_8255003_4	518766.Rmar_1071	0.0007277	50.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
XH3_k127_8255003_0	243090.RB12434	4.348e-43	178.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
XH3_k127_8255003_1	926569.ANT_11560	2.605e-39	165.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH3_k127_8255003_3	1121104.AQXH01000005_gene164	8.963e-05	47.0	COG1404@1|root,COG5276@1|root,COG1404@2|Bacteria,COG5276@2|Bacteria,4PPJ4@976|Bacteroidetes,1IZ3E@117747|Sphingobacteriia	2|Bacteria	O	Protein conserved in bacteria	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FG-GAP,LVIVD,Peptidase_S8,Phytase-like,SLH,TSP_3
XH3_k127_8267042_1	552811.Dehly_0143	3.499e-42	168.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi,34CPQ@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
XH3_k127_8267042_2	880073.Calab_0647	5.881e-09	69.0	COG1361@1|root,COG1595@1|root,COG1361@2|Bacteria,COG1595@2|Bacteria,2NPVV@2323|unclassified Bacteria	2|Bacteria	K	GxGYxYP putative glycoside hydrolase C-terminal domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
XH3_k127_8267042_0	309799.DICTH_0179	1.343e-103	358.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
XH3_k127_8267042_3	1321778.HMPREF1982_02606	4.4e-06	55.0	COG1514@1|root,COG1514@2|Bacteria,1VBG1@1239|Firmicutes,24IF5@186801|Clostridia	186801|Clostridia	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
XH3_k127_8288414_0	671143.DAMO_2856	4.086e-186	597.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
XH3_k127_8288414_3	335543.Sfum_0754	3.92e-07	59.0	COG0810@1|root,COG0810@2|Bacteria,1Q5Z4@1224|Proteobacteria,43A9M@68525|delta/epsilon subdivisions,2X230@28221|Deltaproteobacteria,2MQPN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
XH3_k127_8288414_2	1307759.JOMJ01000003_gene277	7.322e-14	76.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,2MC0G@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
XH3_k127_8288414_1	1335757.SPICUR_02205	8.905e-28	121.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1WWA0@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
XH3_k127_831770_3	906888.JCM19314_797	0.0006341	44.0	COG1404@1|root,COG1404@2|Bacteria,4NM0U@976|Bacteroidetes,1I0NM@117743|Flavobacteriia,3HKCK@363408|Nonlabens	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
XH3_k127_831770_0	768670.Calni_0744	6.777e-115	377.0	COG0752@1|root,COG0752@2|Bacteria,2GEZ4@200930|Deferribacteres	200930|Deferribacteres	J	Glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
XH3_k127_831770_1	1304880.JAGB01000002_gene2020	8.284e-65	226.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
XH3_k127_831770_2	1232410.KI421413_gene669	9.202e-61	217.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,43T33@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
XH3_k127_8338016_0	697281.Mahau_1317	3.842e-129	420.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
XH3_k127_8338016_1	1111069.TCCBUS3UF1_20460	1.213e-122	410.0	COG1249@1|root,COG1249@2|Bacteria,1WJBU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
XH3_k127_8338016_3	671143.DAMO_1594	7.578e-50	186.0	COG0321@1|root,COG0321@2|Bacteria,2NPE7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181,2.8.1.8	ko:K03644,ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07767,R07768,R07769	RC00039,RC00992,RC01978,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
XH3_k127_8338016_4	644282.Deba_0699	5.917e-44	177.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42QX3@68525|delta/epsilon subdivisions,2WPC7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
XH3_k127_8338016_2	1116472.MGMO_114c00080	9.241e-119	400.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,1RXZ7@1236|Gammaproteobacteria,1XE3M@135618|Methylococcales	135618|Methylococcales	S	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
XH3_k127_8338016_5	1254432.SCE1572_45755	8.011e-43	178.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1R8QH@1224|Proteobacteria,42T02@68525|delta/epsilon subdivisions,2WPNU@28221|Deltaproteobacteria,2YUP3@29|Myxococcales	28221|Deltaproteobacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
XH3_k127_8340505_1	105420.BBPO01000004_gene1380	7.478e-20	102.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria,2NGAA@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
XH3_k127_8340505_0	316274.Haur_1889	1.972e-30	134.0	COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
XH3_k127_8400994_2	880073.Calab_3298	3.229e-36	158.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	ebh	-	-	-	-	-	-	-	-	-	-	-	DUF1611,Inhibitor_I9,Peptidase_S8,SLH
XH3_k127_8400994_0	1121930.AQXG01000001_gene1525	3.78e-55	209.0	COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes,1IYUI@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
XH3_k127_8400994_1	269799.Gmet_1209	4.342e-39	162.0	COG2931@1|root,COG2931@2|Bacteria,1QVQT@1224|Proteobacteria	1224|Proteobacteria	Q	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
XH3_k127_8422630_2	28115.HR11_00115	1.61e-05	54.0	2DC21@1|root,2ZCJ0@2|Bacteria,4P13V@976|Bacteroidetes,2FWVP@200643|Bacteroidia,23028@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_8422630_1	373903.Hore_08460	2.322e-17	94.0	COG2834@1|root,COG2834@2|Bacteria,1V6F3@1239|Firmicutes,24MGP@186801|Clostridia,3WAQP@53433|Halanaerobiales	186801|Clostridia	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
XH3_k127_8422630_0	748449.Halha_0600	2.677e-34	144.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,3WB6E@53433|Halanaerobiales	186801|Clostridia	S	hydrophobe amphiphile efflux-3 (HAE3) family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
XH3_k127_8460141_1	1121335.Clst_0225	1.179e-61	216.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,3WJDN@541000|Ruminococcaceae	186801|Clostridia	S	Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
XH3_k127_8460141_2	247490.KSU1_C1639	4.241e-24	109.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
XH3_k127_8460141_4	1173025.GEI7407_2519	1.644e-20	95.0	COG0642@1|root,COG0784@1|root,COG3447@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG3447@2|Bacteria,1GPYK@1117|Cyanobacteria,1HHZI@1150|Oscillatoriales	1117|Cyanobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
XH3_k127_8460141_0	1304885.AUEY01000005_gene892	1.185e-89	304.0	COG0598@1|root,COG0598@2|Bacteria,1RGGI@1224|Proteobacteria,42UX4@68525|delta/epsilon subdivisions,2WQYH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Mg2 transporter protein CorA family protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
XH3_k127_8460141_3	1463900.JOIX01000008_gene7659	8.016e-24	106.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
XH3_k127_8460141_5	445335.CBN_0685	9.349e-12	72.0	COG1633@1|root,COG1633@2|Bacteria,1V4P6@1239|Firmicutes,24IYH@186801|Clostridia,36J9Q@31979|Clostridiaceae	186801|Clostridia	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
XH3_k127_8527997_0	1121918.ARWE01000001_gene736	2.427e-131	429.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43UCA@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
XH3_k127_8527997_1	1329516.JPST01000015_gene789	1.328e-87	301.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,27BH8@186824|Thermoactinomycetaceae	91061|Bacilli	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
XH3_k127_8527997_2	694431.DESACE_07605	2.265e-38	147.0	COG1671@1|root,COG1671@2|Bacteria,1P0CU@1224|Proteobacteria,431PK@68525|delta/epsilon subdivisions,2WX4Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0178 family	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_8527997_3	360107.CHAB381_1488	2.86e-35	141.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2YP3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
XH3_k127_8527997_4	138119.DSY1247	1.081e-07	59.0	COG0348@1|root,COG4659@1|root,COG0348@2|Bacteria,COG4659@2|Bacteria,1UYBF@1239|Firmicutes,24A2I@186801|Clostridia	186801|Clostridia	C	PFAM FMN-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
XH3_k127_8543288_0	304371.MCP_2139	3.052e-72	248.0	COG3369@1|root,arCOG03174@2157|Archaea,2XX0Q@28890|Euryarchaeota,2NAIG@224756|Methanomicrobia	224756|Methanomicrobia	S	SMART zinc finger, CDGSH-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
XH3_k127_8574734_0	755732.Fluta_0365	1.385e-34	151.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hemopexin,Metalloenzyme,Phosphodiest
XH3_k127_8610773_1	485913.Krac_8102	1.898e-49	181.0	2FA33@1|root,342C2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_8610773_0	269797.Mbar_A1366	2.48e-139	468.0	COG0457@1|root,arCOG03045@2157|Archaea,2XVG0@28890|Euryarchaeota	28890|Euryarchaeota	V	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
XH3_k127_8612270_1	1121948.AUAC01000003_gene2378	1.106e-23	110.0	COG0739@1|root,COG4219@1|root,COG0739@2|Bacteria,COG4219@2|Bacteria,1PJ0I@1224|Proteobacteria,2V75H@28211|Alphaproteobacteria,43Z51@69657|Hyphomonadaceae	28211|Alphaproteobacteria	KMT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,Peptidase_M56
XH3_k127_8612270_0	1201288.M900_2209	1.689e-32	137.0	COG0778@1|root,COG0778@2|Bacteria,1NIJ8@1224|Proteobacteria,42WCD@68525|delta/epsilon subdivisions,2WRHM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
XH3_k127_8612270_2	608506.COB47_0807	1.041e-05	48.0	COG1014@1|root,COG1014@2|Bacteria,1TRFJ@1239|Firmicutes,24A29@186801|Clostridia,42GE2@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit	porC	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
XH3_k127_8620888_3	1191523.MROS_0678	6.28e-11	68.0	2C97T@1|root,338QQ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
XH3_k127_8620888_0	1089553.Tph_c26210	3.555e-79	276.0	COG5322@1|root,COG5322@2|Bacteria,1TSXZ@1239|Firmicutes,24992@186801|Clostridia,42EPQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
XH3_k127_8620888_4	1265845.PWEIH_05194	8.413e-06	53.0	COG0346@1|root,COG0346@2|Bacteria,1V48E@1239|Firmicutes,4HHUT@91061|Bacilli,26M4M@186820|Listeriaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	yurT	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
XH3_k127_8620888_2	755732.Fluta_0605	1.765e-38	155.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes,1I0CF@117743|Flavobacteriia,2PAUX@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
XH3_k127_8644316_3	760192.Halhy_2751	2.044e-32	130.0	arCOG12964@1|root,2Z7HP@2|Bacteria,4P10P@976|Bacteroidetes	976|Bacteroidetes	S	Tocopherol cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Tocopherol_cycl
XH3_k127_8644316_1	1047013.AQSP01000098_gene2574	4.313e-47	175.0	COG0778@1|root,COG0778@2|Bacteria,2NQ10@2323|unclassified Bacteria	2|Bacteria	C	Putative TM nitroreductase	noxC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
XH3_k127_8644316_2	1499967.BAYZ01000041_gene2334	1.635e-45	172.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	VVA1313	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
XH3_k127_8644316_4	765912.Thimo_2818	2.311e-24	115.0	COG5012@1|root,COG5012@2|Bacteria,1RE0V@1224|Proteobacteria,1RTR2@1236|Gammaproteobacteria,1WWT8@135613|Chromatiales	135613|Chromatiales	S	cobalamin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
XH3_k127_8644316_0	1499967.BAYZ01000021_gene198	2.536e-52	190.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
XH3_k127_8647241_1	1379698.RBG1_1C00001G1006	2.104e-53	197.0	COG0682@1|root,COG0682@2|Bacteria,2NPK2@2323|unclassified Bacteria	2|Bacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
XH3_k127_8647241_2	555079.Toce_1601	5.172e-32	135.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,42FNR@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM Phosphoribosyltransferase	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
XH3_k127_8647241_0	883.DvMF_2080	6.278e-70	246.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
XH3_k127_8651198_2	330214.NIDE0704	1.136e-11	76.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
XH3_k127_8651198_1	330214.NIDE0749	9.972e-23	112.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
XH3_k127_8651198_0	459349.CLOAM1637	3.342e-43	169.0	COG2859@1|root,COG2859@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
XH3_k127_8655217_1	439481.Aboo_0463	4.611e-35	143.0	COG0477@1|root,arCOG00130@2157|Archaea,2Y726@28890|Euryarchaeota,3F38D@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K19576	-	-	-	-	ko00000,ko02000	2.A.1.2.10	-	-	MFS_1
XH3_k127_8655217_0	1379698.RBG1_1C00001G0503	2.939e-70	261.0	COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
XH3_k127_8670765_2	1163389.OOM_1643	1.074e-28	119.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,460T7@72273|Thiotrichales	72273|Thiotrichales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
XH3_k127_8670765_1	411464.DESPIG_02476	3.753e-41	159.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2M933@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
XH3_k127_8670765_0	1499967.BAYZ01000003_gene5878	3.541e-98	327.0	COG0441@1|root,COG0441@2|Bacteria,2NNMT@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
XH3_k127_8687587_0	639282.DEFDS_0410	1.072e-87	314.0	COG1674@1|root,COG1674@2|Bacteria,2GEWN@200930|Deferribacteres	200930|Deferribacteres	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
XH3_k127_8687587_1	1304874.JAFY01000007_gene2050	7.968e-56	202.0	COG1994@1|root,COG1994@2|Bacteria,3TAT7@508458|Synergistetes	508458|Synergistetes	S	PFAM Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
XH3_k127_8687587_2	357808.RoseRS_2847	1.153e-39	160.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G8YQ@200795|Chloroflexi,375MA@32061|Chloroflexia	32061|Chloroflexia	H	Polynucleotide adenylyltransferase region	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
XH3_k127_872657_0	880073.Calab_2082	4.963e-09	68.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
XH3_k127_8726702_0	518766.Rmar_1280	9.857e-08	65.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,4NKF1@976|Bacteroidetes	976|Bacteroidetes	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,SusE
XH3_k127_8728924_0	459349.CLOAM1811	2.117e-49	196.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K06987,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,DUF4859,FlgD_ig,Peptidase_M14
XH3_k127_8735880_1	1499967.BAYZ01000009_gene5246	2.274e-14	78.0	COG0778@1|root,COG0778@2|Bacteria,2NQZY@2323|unclassified Bacteria	2|Bacteria	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
XH3_k127_8735880_0	1168065.DOK_04978	3.719e-47	181.0	COG3108@1|root,COG3108@2|Bacteria,1RAMQ@1224|Proteobacteria,1S35S@1236|Gammaproteobacteria,1J82H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
XH3_k127_8742069_2	1397527.Q670_07430	4.497e-12	78.0	2BZ6D@1|root,2ZC6J@2|Bacteria,1RBC8@1224|Proteobacteria,1S3G8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_8742069_0	744980.TRICHSKD4_2329	1.777e-35	145.0	2BZD3@1|root,2Z914@2|Bacteria,1R4D8@1224|Proteobacteria,2TTPQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_8742069_1	316058.RPB_1116	5.479e-27	114.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,3JR51@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	glycosylase i	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
XH3_k127_8807752_1	246197.MXAN_0354	0.00062	50.0	COG4961@1|root,COG4961@2|Bacteria,1RB2Y@1224|Proteobacteria	1224|Proteobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
XH3_k127_8807752_0	666686.B1NLA3E_21110	1.507e-26	115.0	COG4960@1|root,COG4960@2|Bacteria,1UPNE@1239|Firmicutes,4IV82@91061|Bacilli	91061|Bacilli	OU	peptidase A24	pulO	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
XH3_k127_8808938_2	1499680.CCFE01000023_gene2362	1.292e-91	316.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	tetA_3	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
XH3_k127_8808938_4	1121468.AUBR01000064_gene946	1.351e-80	280.0	COG1163@1|root,COG1163@2|Bacteria,1TSAP@1239|Firmicutes,24EEW@186801|Clostridia	186801|Clostridia	S	GTP-binding protein HSR1-related	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
XH3_k127_8808938_8	309807.SRU_2466	3.478e-10	70.0	2BFSX@1|root,329MV@2|Bacteria,4P7GD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_8808938_1	673860.AciM339_1534	5.971e-92	317.0	COG4198@1|root,arCOG03573@2157|Archaea,2XZJQ@28890|Euryarchaeota,3F2MZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
XH3_k127_8808938_0	243232.MJ_1018	6.925e-97	326.0	COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota,23Q9F@183939|Methanococci	183939|Methanococci	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
XH3_k127_8808938_5	273068.TTE0526	3.498e-55	198.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,24JNB@186801|Clostridia,42G6W@68295|Thermoanaerobacterales	186801|Clostridia	H	ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
XH3_k127_8808938_3	936572.HMPREF1148_0273	3.344e-89	306.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H1WI@909932|Negativicutes	909932|Negativicutes	E	LAO AO transport system	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
XH3_k127_8808938_7	370438.PTH_1361	7.826e-13	70.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,260X7@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM methylmalonyl-CoA mutase N-terminal domain	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
XH3_k127_8855664_0	247490.KSU1_D0201	4.354e-33	134.0	COG0399@1|root,COG0399@2|Bacteria,2J1H7@203682|Planctomycetes	203682|Planctomycetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
XH3_k127_888910_0	1123371.ATXH01000005_gene2143	7.15e-279	874.0	COG0525@1|root,COG0525@2|Bacteria,2GGVS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
XH3_k127_8921560_0	696369.KI912183_gene767	1.099e-64	231.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,2634Y@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM histidinol phosphate phosphatase HisJ	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
XH3_k127_8921560_1	1519464.HY22_10185	4.197e-09	70.0	COG1555@1|root,COG1555@2|Bacteria,1FD6R@1090|Chlorobi	1090|Chlorobi	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
XH3_k127_8921560_2	880073.Calab_1207	2.535e-07	56.0	COG1555@1|root,COG1555@2|Bacteria,2NRDX@2323|unclassified Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
XH3_k127_8948213_3	861454.HMPREF9099_01633	6.011e-26	117.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,27JH2@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
XH3_k127_8948213_1	1120985.AUMI01000015_gene1635	2.924e-63	229.0	COG0407@1|root,COG0407@2|Bacteria,1U2YU@1239|Firmicutes,4H3AW@909932|Negativicutes	909932|Negativicutes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
XH3_k127_8948213_2	309799.DICTH_0565	2.103e-55	201.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,URO-D
XH3_k127_8948213_0	324925.Ppha_0809	3.091e-64	227.0	COG0500@1|root,COG2226@2|Bacteria,1FE72@1090|Chlorobi	1090|Chlorobi	H	UbiE COQ5	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
XH3_k127_8948769_0	459349.CLOAM0275	1.073e-26	123.0	COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria	2|Bacteria	C	lyase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
XH3_k127_8961445_1	1122176.KB903532_gene2717	3.896e-08	63.0	COG0696@1|root,COG0696@2|Bacteria,4PNG1@976|Bacteroidetes,1J0YG@117747|Sphingobacteriia	976|Bacteroidetes	G	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Phosphodiest
XH3_k127_8961445_0	1329516.JPST01000036_gene3074	9.412e-103	345.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,27BKD@186824|Thermoactinomycetaceae	91061|Bacilli	I	Biotin carboxylase C-terminal domain	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
XH3_k127_8962833_1	1131730.BAVI_23218	3.046e-13	81.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bpr	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8
XH3_k127_8962833_3	1233951.IO90_07770	0.0004327	53.0	COG1520@1|root,COG1520@2|Bacteria,4NSXT@976|Bacteroidetes,1I7KG@117743|Flavobacteriia,3HIR9@358033|Chryseobacterium	976|Bacteroidetes	S	PFAM Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
XH3_k127_8962833_2	621372.ACIH01000198_gene2637	7.352e-07	62.0	COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,26QNY@186822|Paenibacillaceae	91061|Bacilli	O	CarboxypepD_reg-like domain	bprF	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8
XH3_k127_8962833_0	13689.BV96_02300	2.678e-17	87.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,2K1FV@204457|Sphingomonadales	204457|Sphingomonadales	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
XH3_k127_8986960_3	1379698.RBG1_1C00001G0723	1.582e-40	166.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
XH3_k127_8986960_2	1511.CLOST_0657	1.094e-42	163.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,25RAS@186804|Peptostreptococcaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
XH3_k127_8986960_1	246194.CHY_0164	2.605e-68	242.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia,42F4R@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
XH3_k127_8986960_0	1123274.KB899409_gene501	1.333e-72	254.0	COG0388@1|root,COG0388@2|Bacteria,2J9CB@203691|Spirochaetes	203691|Spirochaetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
XH3_k127_8994340_0	682795.AciX8_0544	8.172e-45	175.0	COG2132@1|root,COG2132@2|Bacteria,3Y65V@57723|Acidobacteria,2JMCT@204432|Acidobacteriia	204432|Acidobacteriia	Q	PFAM multicopper oxidase type 2	-	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
XH3_k127_8994340_2	105422.BBPM01000038_gene930	0.0002042	49.0	COG1388@1|root,COG1388@2|Bacteria,2IKMC@201174|Actinobacteria	201174|Actinobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_8994340_1	1122915.AUGY01000012_gene3783	3.681e-08	56.0	2DRAI@1|root,33AYP@2|Bacteria,1U1P7@1239|Firmicutes,4I06Y@91061|Bacilli,273R9@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_8997765_0	1125863.JAFN01000001_gene2597	2.126e-68	244.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WQYR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	acdA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
XH3_k127_8997765_1	1122918.KB907280_gene236	4.597e-30	128.0	COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,4HH35@91061|Bacilli,26SC4@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF541)	bp26	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
XH3_k127_8997765_2	330214.NIDE2488	4.607e-11	67.0	28II6@1|root,2Z8JB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_8999526_0	1379698.RBG1_1C00001G1789	1.033e-65	255.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
XH3_k127_9029985_0	574087.Acear_0362	1.819e-98	339.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WAC6@53433|Halanaerobiales	186801|Clostridia	C	Part of a membrane complex involved in electron transport	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_7,Fer4_9,NQRA_SLBB,RnfC_N
XH3_k127_9029985_1	574087.Acear_0363	1.846e-57	206.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,3WA9X@53433|Halanaerobiales	186801|Clostridia	C	Part of a membrane complex involved in electron transport	-	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
XH3_k127_9060683_6	289376.THEYE_A0886	1.645e-22	98.0	COG0157@1|root,COG0157@2|Bacteria,3J0JY@40117|Nitrospirae	40117|Nitrospirae	H	Quinolinate phosphoribosyl transferase, C-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
XH3_k127_9060683_2	269799.Gmet_0890	3.371e-88	302.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,43U42@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
XH3_k127_9060683_1	880073.Calab_2033	2.056e-108	359.0	COG0536@1|root,COG0536@2|Bacteria,2NNS6@2323|unclassified Bacteria	2|Bacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000003,GO:0000160,GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007059,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0019954,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0034622,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042254,GO:0042255,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043933,GO:0043934,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
XH3_k127_9060683_4	1134474.O59_000640	2.892e-51	187.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1FGMI@10|Cellvibrio	1236|Gammaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0053,iSDY_1059.SDY_4064	CTP_transf_like
XH3_k127_9060683_5	1064535.MELS_0949	5.564e-28	120.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4H4YJ@909932|Negativicutes	909932|Negativicutes	L	RNA methyltransferase, RsmD family	rsmD	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
XH3_k127_9060683_3	459349.CLOAM1805	1.776e-66	233.0	COG1478@1|root,COG1478@2|Bacteria	2|Bacteria	S	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	F420_ligase
XH3_k127_9060683_0	1379698.RBG1_1C00001G1752	2.56e-110	382.0	COG0728@1|root,COG0728@2|Bacteria,2NNX8@2323|unclassified Bacteria	2|Bacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
XH3_k127_9080538_3	1128421.JAGA01000003_gene2954	5.678e-54	204.0	COG2211@1|root,COG2211@2|Bacteria,2NR8E@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
XH3_k127_9080538_0	1111069.TCCBUS3UF1_20490	1.365e-91	310.0	COG0320@1|root,COG0320@2|Bacteria,1WIE7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
XH3_k127_9080538_4	476272.RUMHYD_02026	4.217e-40	168.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3XZBQ@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
XH3_k127_9080538_6	459349.CLOAM1883	2.244e-20	97.0	COG0526@1|root,COG0526@2|Bacteria,2NRMM@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin-like	resA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	AhpC-TSA,Redoxin
XH3_k127_9080538_5	365528.KB891102_gene4456	3.196e-28	117.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria	201174|Actinobacteria	P	Divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
XH3_k127_9080538_7	381666.H16_B2247	1.041e-19	105.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,2VNIJ@28216|Betaproteobacteria,1K4RB@119060|Burkholderiaceae	28216|Betaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
XH3_k127_9080538_1	243274.THEMA_01820	8.968e-80	275.0	COG0552@1|root,COG0552@2|Bacteria,2GBXG@200918|Thermotogae	200918|Thermotogae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
XH3_k127_9080538_2	861299.J421_2945	9.693e-55	216.0	COG1196@1|root,COG1196@2|Bacteria,1ZSY1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
XH3_k127_9093630_1	1382356.JQMP01000004_gene167	7.168e-18	95.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi,27XID@189775|Thermomicrobia	189775|Thermomicrobia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH3_k127_9093630_0	1382356.JQMP01000004_gene167	5.265e-43	181.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi,27XID@189775|Thermomicrobia	189775|Thermomicrobia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
XH3_k127_9098758_0	994573.T472_0207660	1.914e-58	207.0	COG4308@1|root,COG4308@2|Bacteria	2|Bacteria	Q	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	3.3.2.8	ko:K10533	ko00903,map00903	-	R05784,R09387	RC01473,RC02519	ko00000,ko00001,ko01000	-	-	-	DUF2358,LEH,SnoaL_2
XH3_k127_9098758_1	926564.KI911740_gene3463	1.571e-14	80.0	COG1437@1|root,COG1437@2|Bacteria,2IGVX@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
XH3_k127_9114844_0	459349.CLOAM0275	1.527e-37	158.0	COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria	2|Bacteria	C	lyase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
XH3_k127_93186_1	494419.ALPM01000104_gene925	0.0006451	50.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,1WCC1@1268|Micrococcaceae	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
XH3_k127_93186_0	1121430.JMLG01000031_gene1624	4.241e-114	381.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,26071@186807|Peptococcaceae	186801|Clostridia	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
XH3_k127_946150_0	1379698.RBG1_1C00001G1319	1.433e-82	286.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
XH3_k127_946150_1	1120950.KB892817_gene7191	2.646e-43	164.0	COG0454@1|root,COG0456@2|Bacteria,2IIN6@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
XH3_k127_946150_2	1121377.KB906398_gene2138	4.453e-13	79.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,DUF4111,NTP_transf_2
XH3_k127_956736_1	67257.JODR01000003_gene1681	4.603e-76	263.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	-	-	2.3.1.29	ko:K00639,ko:K21784	ko00260,ko00333,ko01130,map00260,map00333,map01130	M00837,M00838	R00371,R11667	RC00004,RC00394	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,PP-binding
XH3_k127_956736_0	1191523.MROS_0175	4.583e-131	440.0	COG1022@1|root,COG1022@2|Bacteria	2|Bacteria	I	Amp-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
XH3_k127_963488_1	663610.JQKO01000014_gene1952	0.0007869	50.0	COG1261@1|root,COG1261@2|Bacteria,1MZIR@1224|Proteobacteria,2UDQ2@28211|Alphaproteobacteria,3NBCV@45404|Beijerinckiaceae	28211|Alphaproteobacteria	NO	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
XH3_k127_963488_0	1201290.M902_1315	3.536e-07	60.0	COG4796@1|root,COG4796@2|Bacteria,1NE2V@1224|Proteobacteria,43EIK@68525|delta/epsilon subdivisions,2MT0C@213481|Bdellovibrionales,2X8H4@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	Bacterial type II and III secretion system protein	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Secretin,T2SS-T3SS_pil_N
XH3_k127_970208_0	1122931.AUAE01000010_gene4432	3.839e-60	213.0	COG4912@1|root,COG4912@2|Bacteria,4NHAJ@976|Bacteroidetes,2G32T@200643|Bacteroidia,22ZIS@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
XH3_k127_970208_2	1121468.AUBR01000001_gene470	5.568e-38	149.0	COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,24JTU@186801|Clostridia,42H4U@68295|Thermoanaerobacterales	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
XH3_k127_970208_1	748449.Halha_2392	5.241e-41	164.0	2DYZV@1|root,34BXN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
XH3_k127_970208_3	1210884.HG799469_gene14157	0.0007364	51.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
XH3_k127_973227_6	671143.DAMO_2756	2.041e-27	123.0	COG0358@1|root,COG0358@2|Bacteria,2NNNJ@2323|unclassified Bacteria	2|Bacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
XH3_k127_973227_1	717772.THIAE_08610	2.551e-88	313.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,45ZT2@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
XH3_k127_973227_7	523845.AQXV01000046_gene838	4.271e-16	81.0	COG0622@1|root,arCOG01141@2157|Archaea,2XX8V@28890|Euryarchaeota,23QUK@183939|Methanococci	183939|Methanococci	S	TIGRFAM phosphodiesterase, MJ0936 family	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
XH3_k127_973227_8	521045.Kole_1937	9.179e-13	76.0	COG0622@1|root,COG0622@2|Bacteria,2GD1H@200918|Thermotogae	200918|Thermotogae	S	TIGRFAM phosphodiesterase, MJ0936 family	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
XH3_k127_973227_3	1379698.RBG1_1C00001G0056	1.861e-71	248.0	COG0313@1|root,COG0313@2|Bacteria,2NP98@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
XH3_k127_973227_5	1158345.JNLL01000001_gene1443	1.945e-33	136.0	COG0558@1|root,COG0558@2|Bacteria,2G4ZX@200783|Aquificae	200783|Aquificae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
XH3_k127_973227_0	370438.PTH_2120	1.314e-98	339.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,2606G@186807|Peptococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
XH3_k127_973227_2	671143.DAMO_0966	9.68e-82	284.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	spoIVFB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
XH3_k127_973227_4	926550.CLDAP_20570	1.406e-55	203.0	COG3634@1|root,COG3634@2|Bacteria,2G6SQ@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
## 1308 queries scanned
## Total time (seconds): 17.926098823547363
## Rate: 72.97 q/s