## Fri Feb 20 03:47:34 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/YHH1_bin.105.fa -m mmseqs --output YHH1_bin.105 --output_dir /data/result/bins/wyx/eggqs50+/YHH1_bin.105 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YHH1_k127_1001966_0	1379698.RBG1_1C00001G1194	6.285e-41	175.0	COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	3.2.1.91	ko:K14194,ko:K19668	ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CHU_C,DUF11,FlgD_ig,PKD,SdrD_B
YHH1_k127_100221_0	1125863.JAFN01000001_gene2769	5.435e-111	363.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2WJ0R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
YHH1_k127_100221_3	880073.Calab_1159	4.091e-15	84.0	2A6YD@1|root,30VTC@2|Bacteria,2NQ0X@2323|unclassified Bacteria	2|Bacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
YHH1_k127_100221_2	246197.MXAN_4198	4.474e-30	136.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2X5KQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
YHH1_k127_100221_1	1379698.RBG1_1C00001G1364	8.198e-66	236.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
YHH1_k127_1002388_0	1307761.L21SP2_2654	5.812e-70	243.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH1_k127_1002388_2	1047013.AQSP01000114_gene700	2.22e-41	154.0	COG3093@1|root,COG3093@2|Bacteria,2NR60@2323|unclassified Bacteria	2|Bacteria	K	Helix-turn-helix XRE-family like proteins	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
YHH1_k127_1002388_3	671143.DAMO_0637	6.869e-33	129.0	COG3549@1|root,COG3549@2|Bacteria,2NRMI@2323|unclassified Bacteria	2|Bacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
YHH1_k127_1002388_4	626887.J057_10481	2.165e-27	114.0	2E32Y@1|root,32Y36@2|Bacteria,1N7G2@1224|Proteobacteria,1SCS8@1236|Gammaproteobacteria,46BEX@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1002388_5	555779.Dthio_PD3209	5.744e-22	96.0	COG2337@1|root,COG2337@2|Bacteria,1RIPH@1224|Proteobacteria,42UKM@68525|delta/epsilon subdivisions,2WQZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH1_k127_1002388_6	579405.Dd703_3545	7.173e-13	75.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW7X@1224|Proteobacteria,1RRF4@1236|Gammaproteobacteria,2JBPV@204037|Dickeya	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32,HTH_33
YHH1_k127_1002388_7	1265507.KB899638_gene947	3.287e-10	68.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_29,HTH_32,HTH_33
YHH1_k127_1002388_8	765911.Thivi_0124	8.15e-08	54.0	COG2337@1|root,COG2337@2|Bacteria,1RIPH@1224|Proteobacteria,1S7VW@1236|Gammaproteobacteria,1WYQY@135613|Chromatiales	135613|Chromatiales	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH1_k127_10029310_4	880073.Calab_2468	1.948e-26	121.0	COG0760@1|root,COG0760@2|Bacteria,2NRND@2323|unclassified Bacteria	2|Bacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N,SurA_N_3
YHH1_k127_10029310_1	1379698.RBG1_1C00001G1778	4.647e-122	398.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
YHH1_k127_10029310_0	1499967.BAYZ01000069_gene1846	2.79e-147	472.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YHH1_k127_10029310_3	880073.Calab_2727	6.17e-34	141.0	COG0382@1|root,COG0382@2|Bacteria,2NQZV@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39,2.5.1.42	ko:K03179,ko:K17105	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00117	R04520,R05000,R05615	RC00209,RC01171,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
YHH1_k127_10029310_5	1122217.KB899568_gene798	8.112e-11	75.0	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,4H27F@909932|Negativicutes	909932|Negativicutes	M	Outer membrane protein, OMP85 family	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YHH1_k127_10029310_2	945713.IALB_1764	3.907e-37	162.0	COG5448@1|root,COG5448@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
YHH1_k127_10096163_0	926550.CLDAP_31550	2.66e-100	344.0	COG4579@1|root,COG4579@2|Bacteria	2|Bacteria	F	[isocitrate dehydrogenase (NADP+)] phosphatase activity	aceK	GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
YHH1_k127_10096163_1	1089551.KE386572_gene4189	3.715e-29	119.0	2A0NG@1|root,32XDJ@2|Bacteria,1N3J7@1224|Proteobacteria,2UD9K@28211|Alphaproteobacteria,4BSDS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10096163_2	1089551.KE386572_gene4189	1.572e-28	118.0	2A0NG@1|root,32XDJ@2|Bacteria,1N3J7@1224|Proteobacteria,2UD9K@28211|Alphaproteobacteria,4BSDS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10105409_2	518766.Rmar_2587	1.835e-48	177.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
YHH1_k127_10105409_0	247490.KSU1_A0073	3.045e-146	473.0	COG0479@1|root,COG0479@2|Bacteria,2IWTB@203682|Planctomycetes	203682|Planctomycetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
YHH1_k127_10105409_1	1449126.JQKL01000008_gene293	3.448e-119	391.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,267RV@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
YHH1_k127_10131093_0	243231.GSU0686	1.229e-124	413.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
YHH1_k127_10131093_1	1379698.RBG1_1C00001G1130	1.11e-61	223.0	COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria	2|Bacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	NAD_kinase
YHH1_k127_10131093_3	28444.JODQ01000002_gene4223	1.165e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,2H8D0@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10131093_2	1122169.AREN01000056_gene2008	2.799e-14	73.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1JD5X@118969|Legionellales	118969|Legionellales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH1_k127_10138177_2	1379698.RBG1_1C00001G1859	4.001e-68	244.0	COG3481@1|root,COG3481@2|Bacteria,2NPNP@2323|unclassified Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
YHH1_k127_10138177_1	1379698.RBG1_1C00001G1858	6.152e-99	338.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
YHH1_k127_10138177_4	1379698.RBG1_1C00001G1857	1.365e-58	217.0	COG0795@1|root,COG0795@2|Bacteria,2NPHN@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
YHH1_k127_10138177_3	1341155.FSS13T_13020	4.446e-60	218.0	COG2227@1|root,COG2227@2|Bacteria,4NF6D@976|Bacteroidetes,1HXVW@117743|Flavobacteriia,2NTAA@237|Flavobacterium	976|Bacteroidetes	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
YHH1_k127_10138177_5	555079.Toce_2076	3.546e-46	171.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia,42GT3@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH1_k127_10138177_0	1379698.RBG1_1C00001G0460	0.0	1120.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
YHH1_k127_10158658_2	641524.ADICYQ_3715	1.032e-95	319.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,47X9D@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH1_k127_10158658_0	1056820.KB900681_gene2859	4.779e-158	507.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH1_k127_10158658_1	330214.NIDE3581	2.888e-125	416.0	COG0382@1|root,COG0560@1|root,COG0382@2|Bacteria,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
YHH1_k127_10194292_0	1125863.JAFN01000001_gene1462	0.0	1034.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
YHH1_k127_10194292_3	1380384.JADN01000004_gene2134	1.985e-36	148.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
YHH1_k127_10194292_4	1121035.AUCH01000008_gene1002	8.535e-24	118.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,2KV2P@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YHH1_k127_10194292_5	1304885.AUEY01000022_gene3410	7.797e-11	67.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2MI3G@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_10194292_2	697281.Mahau_2311	9.5e-45	168.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,42GHN@68295|Thermoanaerobacterales	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
YHH1_k127_10194292_1	469381.Dpep_0433	3.761e-53	193.0	COG2077@1|root,COG2077@2|Bacteria,3TAX1@508458|Synergistetes	508458|Synergistetes	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
YHH1_k127_1020607_1	1379698.RBG1_1C00001G1788	1.85e-112	386.0	COG2067@1|root,COG3292@1|root,COG2067@2|Bacteria,COG3292@2|Bacteria,2NPQZ@2323|unclassified Bacteria	2|Bacteria	I	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Reg_prop,Reprolysin_5,VCBS
YHH1_k127_1020607_0	1379698.RBG1_1C00001G1787	1.019e-135	464.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	DUF1863,PQQ_2
YHH1_k127_10220807_1	314230.DSM3645_29481	2.944e-24	116.0	COG0526@1|root,COG0526@2|Bacteria,2J35Z@203682|Planctomycetes	203682|Planctomycetes	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
YHH1_k127_10220807_0	485918.Cpin_4401	1.387e-28	120.0	COG2755@1|root,COG2755@2|Bacteria,4NJGD@976|Bacteroidetes,1IU06@117747|Sphingobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH1_k127_10230796_3	477228.YO5_04217	1.27e-40	157.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1Z0UA@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	P	K -dependent Na Ca	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
YHH1_k127_10230796_0	497964.CfE428DRAFT_6094	8.519e-132	431.0	COG0475@1|root,COG0475@2|Bacteria	2|Bacteria	P	glutathione-regulated potassium exporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YHH1_k127_10230796_1	1434325.AZQN01000011_gene3742	1.335e-66	235.0	28N6F@1|root,2ZBBB@2|Bacteria,4NGM1@976|Bacteroidetes,47P0U@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10230796_2	1121481.AUAS01000002_gene3332	4.883e-64	235.0	COG1680@1|root,COG1680@2|Bacteria,4NEEP@976|Bacteroidetes,47KW2@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH1_k127_10252690_1	1121930.AQXG01000002_gene2374	1.181e-146	479.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1IUW3@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
YHH1_k127_10252690_4	690850.Desaf_2134	8.319e-57	214.0	COG5653@1|root,COG5653@2|Bacteria,1Q8ZI@1224|Proteobacteria,431YG@68525|delta/epsilon subdivisions,2WWCM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
YHH1_k127_10252690_7	1254432.SCE1572_32910	7.505e-23	115.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2WJNS@28221|Deltaproteobacteria,2Z3JN@29|Myxococcales	28221|Deltaproteobacteria	KLT	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,Pkinase
YHH1_k127_10252690_2	1121430.JMLG01000001_gene2393	6.801e-95	328.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,267C6@186807|Peptococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07714,ko:K10943	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_10252690_5	1237149.C900_05018	3.641e-49	179.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,Cupin_7,DUF4440,HTH_18
YHH1_k127_10252690_6	215803.DB30_7465	7.16e-30	126.0	2E69S@1|root,330XP@2|Bacteria,1N7XM@1224|Proteobacteria	1224|Proteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_5
YHH1_k127_10252690_0	869210.Marky_1927	7.138e-163	523.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
YHH1_k127_10280199_4	1122214.AQWH01000003_gene3933	2.944e-33	133.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YHH1_k127_10280199_6	1379698.RBG1_1C00001G0791	3.105e-15	81.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YHH1_k127_10280199_1	1382356.JQMP01000001_gene1276	5.75e-125	411.0	COG0451@1|root,COG0451@2|Bacteria,2G5PB@200795|Chloroflexi	200795|Chloroflexi	M	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YHH1_k127_10280199_9	521096.Tpau_1786	3.653e-05	54.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria	201174|Actinobacteria	S	regulatory protein RecX	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
YHH1_k127_10280199_0	1123371.ATXH01000014_gene1607	4.153e-235	756.0	COG0013@1|root,COG0013@2|Bacteria,2GH36@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YHH1_k127_10280199_2	517418.Ctha_0722	1.668e-72	252.0	COG1646@1|root,COG1646@2|Bacteria,1FEV5@1090|Chlorobi	1090|Chlorobi	I	PcrB family	-	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
YHH1_k127_10280199_7	573061.Clocel_2117	3.898e-08	65.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,24AB7@186801|Clostridia,36ERI@31979|Clostridiaceae	186801|Clostridia	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
YHH1_k127_10280199_3	1484460.JSWG01000009_gene300	1.666e-66	247.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1HZHR@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH1_k127_10280199_5	672.VV93_v1c35110	5.571e-30	129.0	COG0739@1|root,COG0739@2|Bacteria,1QJWI@1224|Proteobacteria,1THY9@1236|Gammaproteobacteria,1XXW6@135623|Vibrionales	135623|Vibrionales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH1_k127_10285067_7	635013.TherJR_1519	2.971e-05	55.0	COG5581@1|root,COG5581@2|Bacteria,1VERW@1239|Firmicutes,24NU7@186801|Clostridia,261QY@186807|Peptococcaceae	186801|Clostridia	M	PFAM PilZ domain	pilZ	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
YHH1_k127_10285067_1	1379698.RBG1_1C00001G1108	3.948e-96	323.0	COG1191@1|root,COG1191@2|Bacteria,2NPMN@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH1_k127_10285067_5	1196028.ALEF01000006_gene3242	8.178e-28	123.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,4HCWZ@91061|Bacilli,4C6F2@84406|Virgibacillus	91061|Bacilli	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	ylxH	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
YHH1_k127_10285067_6	1382315.JPOI01000001_gene2967	8.921e-20	102.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H9VG@91061|Bacilli,1WFDN@129337|Geobacillus	91061|Bacilli	N	SRP54-type protein, GTPase domain	flhF	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
YHH1_k127_10285067_0	574087.Acear_1624	1.003e-223	713.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia,3WABD@53433|Halanaerobiales	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
YHH1_k127_10285067_2	639282.DEFDS_0413	9.378e-92	313.0	COG1377@1|root,COG1377@2|Bacteria,2GESV@200930|Deferribacteres	200930|Deferribacteres	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
YHH1_k127_10285067_4	457570.Nther_1411	2.456e-41	162.0	COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,24ECW@186801|Clostridia	186801|Clostridia	N	flagellar biosynthetic protein FliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
YHH1_k127_10286207_0	316067.Geob_0375	0.0	1901.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,43TSH@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	por	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH1_k127_10290128_2	1047013.AQSP01000095_gene2301	2.447e-22	108.0	2DS9E@1|root,32VU1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10290128_0	1347392.CCEZ01000011_gene2437	2.31e-112	377.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,36EK3@31979|Clostridiaceae	186801|Clostridia	K	aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
YHH1_k127_10290128_1	1122135.KB893170_gene2750	1.081e-95	330.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,2TQZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
YHH1_k127_10311264_5	709991.Odosp_2214	4.237e-05	56.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,2FNUY@200643|Bacteroidia,22VV4@171551|Porphyromonadaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_10311264_2	865861.AZSU01000001_gene486	4.321e-63	228.0	COG0697@1|root,COG0697@2|Bacteria,1V009@1239|Firmicutes,24DF1@186801|Clostridia,36GKS@31979|Clostridiaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_10311264_4	1049564.TevJSym_ai00750	1.881e-09	68.0	2CEM8@1|root,344D4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10311264_3	1094715.CM001373_gene2649	1.289e-14	79.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1JEPF@118969|Legionellales	118969|Legionellales	J	Sigma 54 modulation protein / S30EA ribosomal protein	yhbH	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
YHH1_k127_10311264_0	1379698.RBG1_1C00001G0551	1.046e-151	493.0	COG1508@1|root,COG1508@2|Bacteria,2NNZA@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
YHH1_k127_10311264_1	1379698.RBG1_1C00001G0549	1.017e-103	344.0	COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria	2|Bacteria	S	lipopolysaccharide transport protein B ATP-binding component of ABC superfamily	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
YHH1_k127_10311264_6	1121904.ARBP01000026_gene661	0.0001296	55.0	COG0457@1|root,COG0457@2|Bacteria,4NKK4@976|Bacteroidetes,47UDJ@768503|Cytophagia	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
YHH1_k127_1031785_2	1117108.PAALTS15_19598	9.655e-05	52.0	2DTGX@1|root,33KA4@2|Bacteria,1TZYJ@1239|Firmicutes,4I984@91061|Bacilli,2715P@186822|Paenibacillaceae	91061|Bacilli	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
YHH1_k127_1031785_1	1379698.RBG1_1C00001G1395	8.72e-33	130.0	28IS3@1|root,2Z8R9@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
YHH1_k127_10332896_5	1298593.TOL_3110	2.379e-37	147.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1XK3H@135619|Oceanospirillales	135619|Oceanospirillales	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
YHH1_k127_10332896_3	243231.GSU0525	1.587e-45	169.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,43UNI@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
YHH1_k127_10332896_0	909663.KI867150_gene2148	0.0	1270.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MQ8R@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
YHH1_k127_10332896_4	1191523.MROS_0287	1.648e-38	147.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YHH1_k127_10332896_2	1379698.RBG1_1C00001G1850	3.507e-64	230.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH1_k127_10332896_7	1088868.CIN_06300	4.496e-05	55.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria,2JRP8@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ompR	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_10332896_1	1379698.RBG1_1C00001G1619	1.401e-74	258.0	COG0785@1|root,COG0785@2|Bacteria,2NPE4@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	1.8.4.11,1.8.4.12	ko:K06196,ko:K12267	-	-	-	-	ko00000,ko01000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
YHH1_k127_10332896_6	370438.PTH_0129	9.961e-12	74.0	COG3222@1|root,COG3222@2|Bacteria,1VANQ@1239|Firmicutes,24GQ0@186801|Clostridia,2630Q@186807|Peptococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
YHH1_k127_1035589_17	1443125.Z962_06795	1.076e-10	71.0	COG1479@1|root,COG1479@2|Bacteria,1TPAT@1239|Firmicutes,24CP3@186801|Clostridia,36H6W@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262,DUF4268
YHH1_k127_1035589_0	945713.IALB_1079	2.004e-242	760.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
YHH1_k127_1035589_3	945713.IALB_1080	1.105e-153	495.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_1035589_5	1449126.JQKL01000022_gene150	5.339e-105	351.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,2681I@186813|unclassified Clostridiales	186801|Clostridia	C	Phosphate acetyl/butaryl transferase	pta	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
YHH1_k127_1035589_4	880073.Calab_1379	2.16e-132	430.0	COG1186@1|root,COG1186@2|Bacteria,2NNU3@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH1_k127_1035589_9	436114.SYO3AOP1_1739	6.058e-58	208.0	COG0491@1|root,COG0491@2|Bacteria,2G479@200783|Aquificae	200783|Aquificae	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH1_k127_1035589_13	635013.TherJR_1575	9.638e-44	170.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,26325@186807|Peptococcaceae	186801|Clostridia	E	histidinol phosphate phosphatase	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
YHH1_k127_1035589_11	351160.RCIX1098	1.723e-50	186.0	COG2094@1|root,arCOG04295@2157|Archaea,2Y0AE@28890|Euryarchaeota,2NB07@224756|Methanomicrobia	224756|Methanomicrobia	L	alkylbase DNA N-glycosylase activity	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
YHH1_k127_1035589_12	247490.KSU1_B0618	2.349e-47	177.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	MA20_27160	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50
YHH1_k127_1035589_2	945713.IALB_0362	2.059e-163	535.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	msbA	-	-	ko:K02021,ko:K06147,ko:K06148,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH1_k127_1035589_10	324925.Ppha_0387	1.087e-51	198.0	COG0438@1|root,COG0438@2|Bacteria,1FD90@1090|Chlorobi	1090|Chlorobi	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_1035589_16	290512.Paes_0354	3.725e-29	131.0	COG0859@1|root,COG0859@2|Bacteria,1FDVI@1090|Chlorobi	1090|Chlorobi	H	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
YHH1_k127_1035589_6	1379698.RBG1_1C00001G1037	4e-74	257.0	COG0463@1|root,COG0463@2|Bacteria,2NPA5@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 2	kdtX	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
YHH1_k127_1035589_8	1379698.RBG1_1C00001G1038	3.489e-59	220.0	COG0859@1|root,COG0859@2|Bacteria,2NPXQ@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH1_k127_1035589_1	880073.Calab_0005	1.154e-218	704.0	COG0317@1|root,COG0317@2|Bacteria,2NNM0@2323|unclassified Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
YHH1_k127_1035589_14	1144307.PMI04_00572	3.022e-37	151.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,2TU7K@28211|Alphaproteobacteria,2K345@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphorylase superfamily	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YHH1_k127_1035589_7	439235.Dalk_0201	4.113e-68	236.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42UR6@68525|delta/epsilon subdivisions,2WR1E@28221|Deltaproteobacteria,2MPYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
YHH1_k127_1035589_15	339860.Msp_0117	5.076e-36	139.0	COG3425@1|root,arCOG01767@2157|Archaea,2XTWE@28890|Euryarchaeota,23NSI@183925|Methanobacteria	183925|Methanobacteria	I	Belongs to the UPF0219 family	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,HMG_CoA_synt_N
YHH1_k127_10364726_0	1353276.JADR01000002_gene2015	1.848e-18	98.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,FG-GAP_2,LVIVD,TSP_3
YHH1_k127_10364726_1	84531.JMTZ01000005_gene2391	3.173e-09	66.0	COG2304@1|root,COG2304@2|Bacteria,1R8EZ@1224|Proteobacteria,1SG9K@1236|Gammaproteobacteria,1XB1U@135614|Xanthomonadales	135614|Xanthomonadales	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
YHH1_k127_10392800_3	929556.Solca_2518	5.355e-26	109.0	2CMS6@1|root,32SFE@2|Bacteria,4NWI0@976|Bacteroidetes,1IYER@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH1_k127_10392800_6	1122179.KB890480_gene3150	1.647e-13	76.0	295U4@1|root,2ZT58@2|Bacteria,4PQ2P@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
YHH1_k127_10392800_1	717231.Flexsi_0322	5.261e-45	165.0	COG1917@1|root,COG1917@2|Bacteria,2GGHG@200930|Deferribacteres	200930|Deferribacteres	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YHH1_k127_10392800_0	1047013.AQSP01000073_gene1092	6.837e-162	527.0	COG1305@1|root,COG3391@1|root,COG1305@2|Bacteria,COG3391@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Transglut_core
YHH1_k127_10392800_7	714943.Mucpa_0143	2.778e-10	76.0	2DEAF@1|root,2ZM5X@2|Bacteria,4PMD1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10392800_2	397278.JOJN01000019_gene2333	1.088e-34	153.0	COG2132@1|root,COG2133@1|root,COG2982@1|root,COG3291@1|root,COG3401@1|root,COG4733@1|root,COG2132@2|Bacteria,COG2133@2|Bacteria,COG2982@2|Bacteria,COG3291@2|Bacteria,COG3401@2|Bacteria,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PA14
YHH1_k127_10392800_4	929703.KE386491_gene1250	2.369e-15	90.0	COG3188@1|root,COG3188@2|Bacteria,4NHCJ@976|Bacteroidetes,47K9Y@768503|Cytophagia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10392800_5	1434325.AZQN01000011_gene3742	3.135e-14	73.0	28N6F@1|root,2ZBBB@2|Bacteria,4NGM1@976|Bacteroidetes,47P0U@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1039397_2	592015.HMPREF1705_00166	1.968e-38	147.0	COG0438@1|root,COG0438@2|Bacteria,3TC5G@508458|Synergistetes	508458|Synergistetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1039397_0	891968.Anamo_1586	1.996e-270	850.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,3TA4P@508458|Synergistetes	508458|Synergistetes	G	PFAM glycosyl transferase family 20	-	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
YHH1_k127_1039397_7	1123368.AUIS01000010_gene2348	0.0003359	49.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,1S20Q@1236|Gammaproteobacteria,2ND9S@225057|Acidithiobacillales	225057|Acidithiobacillales	L	NUDIX domain	-	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
YHH1_k127_1039397_3	342949.PNA2_1727	3.182e-36	148.0	COG0500@1|root,arCOG01791@2157|Archaea,2XZTQ@28890|Euryarchaeota,245BV@183968|Thermococci	183968|Thermococci	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH1_k127_1039397_1	983917.RGE_38700	7.418e-44	165.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
YHH1_k127_1039397_4	325777.GW15_0219000	2.677e-35	138.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,1T193@1236|Gammaproteobacteria,1X6HF@135614|Xanthomonadales	135614|Xanthomonadales	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
YHH1_k127_1039397_5	1095769.CAHF01000006_gene1930	2.979e-24	105.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,2VSPX@28216|Betaproteobacteria,474M4@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH1_k127_1039397_6	867902.Ornrh_0358	4.652e-10	61.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1HYV0@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
YHH1_k127_10402509_1	1379698.RBG1_1C00001G1071	1.47e-53	193.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH1_k127_10402509_0	1094980.Mpsy_2456	2.503e-162	525.0	COG0415@1|root,arCOG02840@2157|Archaea,2XTVM@28890|Euryarchaeota,2NAIC@224756|Methanomicrobia	224756|Methanomicrobia	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
YHH1_k127_10402509_2	1408433.JHXV01000022_gene3146	3.433e-21	108.0	COG1807@1|root,COG1807@2|Bacteria,4NM44@976|Bacteroidetes,1IF0R@117743|Flavobacteriia,2PBBM@246874|Cryomorphaceae	976|Bacteroidetes	M	Alg9-like mannosyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22
YHH1_k127_10402509_3	643867.Ftrac_1458	2.801e-08	60.0	COG0346@1|root,COG0346@2|Bacteria,4NRSZ@976|Bacteroidetes,47QSC@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YHH1_k127_10402509_4	63737.Npun_F1211	2.3e-05	51.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG3850@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3850@2|Bacteria,1G09B@1117|Cyanobacteria,1HJ6D@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
YHH1_k127_10408191_2	865938.Weevi_2010	1.815e-07	60.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1HYEQ@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
YHH1_k127_10408191_1	1341151.ASZU01000004_gene417	2.872e-36	145.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,27BVF@186824|Thermoactinomycetaceae	91061|Bacilli	H	Cytidylyltransferase-like	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YHH1_k127_10408191_0	1379698.RBG1_1C00001G0871	2.24e-237	755.0	COG0749@1|root,COG0749@2|Bacteria,2NNKA@2323|unclassified Bacteria	2|Bacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
YHH1_k127_10427772_2	1049564.TevJSym_bc00290	1.869e-76	264.0	28JXP@1|root,2Z9N4@2|Bacteria,1MXG4@1224|Proteobacteria,1S2DJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
YHH1_k127_10427772_0	1123393.KB891316_gene2015	2.785e-140	456.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2VIQW@28216|Betaproteobacteria,1KSGA@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YHH1_k127_10427772_1	1049564.TevJSym_bb00270	8.748e-91	311.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1J4XD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
YHH1_k127_10427772_3	35754.JNYJ01000007_gene2903	5.929e-13	78.0	COG4932@1|root,COG5295@1|root,COG4932@2|Bacteria,COG5295@2|Bacteria,2I434@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF11,SdrD_B
YHH1_k127_10460384_5	868131.MSWAN_0220	8.156e-22	97.0	COG0674@1|root,arCOG01607@2157|Archaea,2Y7K5@28890|Euryarchaeota,23NP4@183925|Methanobacteria	183925|Methanobacteria	C	ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
YHH1_k127_10460384_0	1125863.JAFN01000001_gene2945	2.889e-104	347.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria	1224|Proteobacteria	C	PFAM Thiamine pyrophosphate	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
YHH1_k127_10460384_3	909663.KI867149_gene3458	5.37e-52	190.0	COG1014@1|root,COG1014@2|Bacteria,1RAQ4@1224|Proteobacteria,43BEE@68525|delta/epsilon subdivisions,2WN0D@28221|Deltaproteobacteria,2MRMB@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	korC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
YHH1_k127_10460384_4	1051646.VITU9109_21764	4.474e-42	158.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1XX25@135623|Vibrionales	135623|Vibrionales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YHH1_k127_10460384_2	1236689.MMALV_14900	1.866e-66	242.0	COG3875@1|root,arCOG02046@2157|Archaea,2XVDD@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
YHH1_k127_10460384_1	1379698.RBG1_1C00001G1803	5.152e-92	308.0	COG0039@1|root,COG0039@2|Bacteria,2NNY8@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1360	Ldh_1_C,Ldh_1_N
YHH1_k127_10518248_1	1499967.BAYZ01000080_gene895	3.803e-70	242.0	COG0500@1|root,COG2226@2|Bacteria,2NP8K@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	arsM	-	2.1.1.137,2.1.1.79	ko:K00574,ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
YHH1_k127_10518248_0	1121918.ARWE01000001_gene2083	3.296e-172	547.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Bile acid sodium symporter	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
YHH1_k127_10518248_2	1380390.JIAT01000010_gene3916	1.357e-21	102.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2HEP3@201174|Actinobacteria,4CTHA@84995|Rubrobacteria	84995|Rubrobacteria	T	low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YHH1_k127_10520139_3	1121438.JNJA01000002_gene3653	4.25e-13	82.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2X1VD@28221|Deltaproteobacteria,2MEI5@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
YHH1_k127_10520139_1	251229.Chro_3352	5.27e-52	202.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2202@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,3VMER@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
YHH1_k127_10520139_2	909663.KI867150_gene441	7.167e-50	181.0	COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,42S64@68525|delta/epsilon subdivisions,2WNPP@28221|Deltaproteobacteria,2MRRN@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH1_k127_10520139_0	323261.Noc_1756	6.281e-91	312.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T3Z7@1236|Gammaproteobacteria,1X2QD@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YHH1_k127_10525199_3	944479.JQLX01000013_gene1440	2.486e-24	119.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
YHH1_k127_10525199_2	1379698.RBG1_1C00001G0480	9.522e-59	212.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
YHH1_k127_10525199_0	1379698.RBG1_1C00001G0481	3.983e-87	293.0	COG1716@1|root,COG1716@2|Bacteria,2NQ4X@2323|unclassified Bacteria	2|Bacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,DUF4388,FHA,Yop-YscD_cpl
YHH1_k127_10525199_1	1379698.RBG1_1C00001G0485	1.948e-81	284.0	COG2025@1|root,COG2025@2|Bacteria,2NNR6@2323|unclassified Bacteria	2|Bacteria	C	Electron transfer flavoprotein	fixB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	iAF987.Gmet_2066,iAF987.Gmet_2257	ETF,ETF_alpha,Fer4
YHH1_k127_10525199_5	755732.Fluta_2725	2.129e-06	60.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
YHH1_k127_10525199_4	1449357.JQLK01000001_gene2184	2.986e-07	63.0	2DRZU@1|root,33DVD@2|Bacteria,1WI81@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YHH1_k127_10527619_1	1242864.D187_009931	4.748e-36	138.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJBM@28221|Deltaproteobacteria,2YTUN@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
YHH1_k127_10527619_0	1232410.KI421418_gene2350	1.405e-63	230.0	COG2067@1|root,COG2067@2|Bacteria,1RFDS@1224|Proteobacteria,42UMQ@68525|delta/epsilon subdivisions,2WQY1@28221|Deltaproteobacteria,43TT0@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
YHH1_k127_10623382_2	665952.HMPREF1015_00491	4.436e-81	274.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,1ZANR@1386|Bacillus	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YHH1_k127_10623382_0	635013.TherJR_1870	1.914e-193	631.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,2602M@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
YHH1_k127_10623382_3	1408422.JHYF01000009_gene2000	2.067e-08	60.0	COG3027@1|root,COG3027@2|Bacteria,1VIXT@1239|Firmicutes,24RYN@186801|Clostridia,36ISE@31979|Clostridiaceae	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
YHH1_k127_10623382_1	1379698.RBG1_1C00001G1123	6.966e-139	451.0	COG1418@1|root,COG1418@2|Bacteria,2NNU5@2323|unclassified Bacteria	2|Bacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
YHH1_k127_10635014_2	690850.Desaf_0357	9.335e-20	91.0	COG2155@1|root,COG2155@2|Bacteria,1N77I@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
YHH1_k127_10635014_0	452637.Oter_1107	5.455e-71	251.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
YHH1_k127_10635014_1	1094980.Mpsy_0682	7.054e-39	151.0	COG2335@1|root,arCOG03335@2157|Archaea,2XY3U@28890|Euryarchaeota,2NB0I@224756|Methanomicrobia	224756|Methanomicrobia	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
YHH1_k127_10635014_3	1121403.AUCV01000005_gene233	1.569e-18	97.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria,2MHV1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
YHH1_k127_10635392_0	671143.DAMO_1287	4.133e-212	663.0	COG2801@1|root,COG2801@2|Bacteria,2NQ4I@2323|unclassified Bacteria	2|Bacteria	L	Homeodomain-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
YHH1_k127_10675194_1	1095769.CAHF01000018_gene822	1.065e-186	588.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2VHEX@28216|Betaproteobacteria,472KJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
YHH1_k127_10675194_2	760117.JN27_15570	6.388e-82	277.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2VJ4X@28216|Betaproteobacteria,474C3@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
YHH1_k127_10675194_0	1095769.CAHF01000018_gene821	1.049e-267	838.0	COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,2VJ2Q@28216|Betaproteobacteria,47290@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
YHH1_k127_10675194_3	1304877.KI519399_gene2903	2.131e-27	116.0	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3JVBW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH1_k127_10684223_0	1121422.AUMW01000005_gene576	1.791e-120	396.0	COG0620@1|root,COG0620@2|Bacteria,1TQX4@1239|Firmicutes,24A5D@186801|Clostridia,260DR@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10684223_1	686340.Metal_0248	1.567e-101	335.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,1S4UH@1236|Gammaproteobacteria,1XEJU@135618|Methylococcales	135618|Methylococcales	S	Mut7-C ubiquitin	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C,Ub-Mut7C
YHH1_k127_10705253_1	1379698.RBG1_1C00001G1312	1.147e-27	122.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	plnP	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YHH1_k127_10705253_0	386415.NT01CX_1414	5.111e-184	586.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,36ET7@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
YHH1_k127_10705253_2	1123248.KB893316_gene4614	2.036e-14	74.0	COG2312@1|root,COG2312@2|Bacteria,4NF9R@976|Bacteroidetes,1IV2U@117747|Sphingobacteriia	976|Bacteroidetes	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
YHH1_k127_10708267_0	1408422.JHYF01000011_gene3429	7.74e-14	84.0	COG1664@1|root,COG1664@2|Bacteria,1V1NS@1239|Firmicutes,24TEV@186801|Clostridia,36ME3@31979|Clostridiaceae	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10750077_1	330214.NIDE3970	5.09e-97	323.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	VVA0018	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
YHH1_k127_10750077_0	330214.NIDE3968	2.284e-230	719.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH1_k127_10759258_0	1122176.KB903556_gene4074	5.64e-174	563.0	COG2304@1|root,COG3291@1|root,COG4386@1|root,COG4935@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,COG4935@2|Bacteria,4P3B4@976|Bacteroidetes	976|Bacteroidetes	O	Immunoglobulin like	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR
YHH1_k127_10768845_5	396588.Tgr7_2398	3.339e-58	207.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	neuA	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,Lipase_GDSL_2
YHH1_k127_10768845_0	396588.Tgr7_2359	5.309e-241	762.0	COG0451@1|root,COG0673@1|root,COG0451@2|Bacteria,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GFO_IDH_MocA
YHH1_k127_10768845_6	396588.Tgr7_2397	4.076e-46	175.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1RNZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Gram-negative-bacterium-type cell wall biogenesis	ycbC	GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	DUF218
YHH1_k127_10768845_3	396588.Tgr7_2367	1.311e-78	272.0	COG1073@1|root,COG1073@2|Bacteria,1RDA0@1224|Proteobacteria,1S647@1236|Gammaproteobacteria,1WYMV@135613|Chromatiales	135613|Chromatiales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
YHH1_k127_10768845_4	396588.Tgr7_2366	5.341e-75	264.0	COG1073@1|root,COG1073@2|Bacteria,1R61B@1224|Proteobacteria	1224|Proteobacteria	T	TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
YHH1_k127_10768845_2	395961.Cyan7425_3345	4.29e-99	326.0	COG0529@1|root,COG0529@2|Bacteria,1G21C@1117|Cyanobacteria,3KGJR@43988|Cyanothece	1117|Cyanobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
YHH1_k127_10768845_1	338963.Pcar_1807	1.423e-129	422.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,42N94@68525|delta/epsilon subdivisions,2WJH4@28221|Deltaproteobacteria,43SB4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NmrA-like family	galE	-	5.1.3.2,5.1.3.5	ko:K01784,ko:K12448	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01473,R02984	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH1_k127_10782740_0	1208323.B30_15591	6.292e-55	216.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2TTUP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Belongs to the 5'-nucleotidase family	MA20_07595	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos
YHH1_k127_10784704_0	697281.Mahau_0741	1.61e-162	530.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,42EXS@68295|Thermoanaerobacterales	186801|Clostridia	E	M3B, thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YHH1_k127_10784704_1	765912.Thimo_3316	1.804e-27	116.0	COG0824@1|root,COG0824@2|Bacteria,1N63F@1224|Proteobacteria,1SB06@1236|Gammaproteobacteria,1WYXM@135613|Chromatiales	135613|Chromatiales	S	PFAM thioesterase superfamily	-	-	3.1.2.28	ko:K12073	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT_2
YHH1_k127_10784704_2	266117.Rxyl_2891	1.145e-06	51.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4CPCU@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
YHH1_k127_10813791_0	1379698.RBG1_1C00001G0606	4.358e-230	727.0	COG0173@1|root,COG0173@2|Bacteria,2NNP3@2323|unclassified Bacteria	2|Bacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iJN678.aspS,iSFV_1184.SFV_1868	GAD,tRNA-synt_2,tRNA_anti-codon
YHH1_k127_10813791_1	1379698.RBG1_1C00001G0609	7.472e-120	393.0	COG1702@1|root,COG1702@2|Bacteria,2NNZF@2323|unclassified Bacteria	2|Bacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
YHH1_k127_10813791_2	880073.Calab_2813	3.845e-115	398.0	COG1480@1|root,COG1480@2|Bacteria,2NP1K@2323|unclassified Bacteria	2|Bacteria	S	7TM receptor with intracellular HD hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
YHH1_k127_10813791_3	608538.HTH_0070	3.097e-18	91.0	COG0319@1|root,COG0319@2|Bacteria,2G5AR@200783|Aquificae	200783|Aquificae	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
YHH1_k127_10813791_4	771875.Ferpe_1130	5.164e-12	75.0	COG1253@1|root,COG1253@2|Bacteria,2GCB4@200918|Thermotogae	200918|Thermotogae	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
YHH1_k127_1082059_1	671143.DAMO_2283	3.38e-33	132.0	COG0474@1|root,COG0474@2|Bacteria,2NNSC@2323|unclassified Bacteria	2|Bacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
YHH1_k127_1082059_2	1121939.L861_09960	5.285e-18	92.0	2EAYI@1|root,334ZG@2|Bacteria,1N8W1@1224|Proteobacteria,1SDMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1082059_0	207559.Dde_1891	1.941e-101	341.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42SS8@68525|delta/epsilon subdivisions,2WPMH@28221|Deltaproteobacteria,2MAUU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
YHH1_k127_10833861_1	945713.IALB_2034	6.003e-167	539.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
YHH1_k127_10833861_4	1379698.RBG1_1C00001G1268	4.197e-78	275.0	COG0420@1|root,COG0420@2|Bacteria,2NQ16@2323|unclassified Bacteria	2|Bacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
YHH1_k127_10833861_2	1379698.RBG1_1C00001G0987	2.562e-158	513.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_10833861_5	521674.Plim_3136	1.852e-63	229.0	COG2148@1|root,COG2148@2|Bacteria,2IX7E@203682|Planctomycetes	203682|Planctomycetes	M	involved in lipopolysaccharide	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
YHH1_k127_10833861_12	880073.Calab_2217	8.782e-25	117.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
YHH1_k127_10833861_6	1379698.RBG1_1C00001G0405	4.534e-63	225.0	COG4784@1|root,COG4784@2|Bacteria,2NS4E@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M48	MA20_40030	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M48
YHH1_k127_10833861_0	1123376.AUIU01000014_gene636	1.655e-169	556.0	COG1449@1|root,COG1449@2|Bacteria,3J0AQ@40117|Nitrospirae	40117|Nitrospirae	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
YHH1_k127_10833861_18	204536.SULAZ_0168	5.682e-05	53.0	COG1729@1|root,COG2956@1|root,COG1729@2|Bacteria,COG2956@2|Bacteria,2G4XE@200783|Aquificae	200783|Aquificae	G	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PPR,TPR_16,TPR_2,TPR_6,TPR_8
YHH1_k127_10833861_13	1379698.RBG1_1C00001G1171	2.314e-24	117.0	COG2067@1|root,COG2067@2|Bacteria,2NRR0@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
YHH1_k127_10833861_8	1379698.RBG1_1C00001G1172	1.511e-54	197.0	COG0503@1|root,COG0503@2|Bacteria,2NPGX@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	PRTase_2,Pribosyltran,TRSP
YHH1_k127_10833861_17	518766.Rmar_1812	3.41e-18	88.0	COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes,1FJMR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YHH1_k127_10833861_10	1379698.RBG1_1C00001G1174	1.103e-40	156.0	COG1611@1|root,COG1611@2|Bacteria,2NPJB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DNA_processg_A,Lysine_decarbox
YHH1_k127_10833861_7	1278073.MYSTI_04936	2.337e-59	214.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,2YVC8@29|Myxococcales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
YHH1_k127_10833861_9	1379698.RBG1_1C00001G1176	1.46e-46	177.0	COG1216@1|root,COG1216@2|Bacteria,2NS4X@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase family 2	XK27_08075	-	-	-	-	-	-	-	-	-	-	-	DUF2062,Glycos_transf_2,GtrA,Lip_A_acyltrans
YHH1_k127_10833861_19	1267533.KB906740_gene313	0.0002031	44.0	COG1961@1|root,COG1961@2|Bacteria,3Y3F6@57723|Acidobacteria,2JKJ1@204432|Acidobacteriia	204432|Acidobacteriia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
YHH1_k127_10833861_14	1379698.RBG1_1C00001G1177	5.592e-23	102.0	COG0789@1|root,COG0789@2|Bacteria,2NQ3P@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, mercury resistance	ycgE	-	-	ko:K19591,ko:K22491	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR_1
YHH1_k127_10833861_3	1379698.RBG1_1C00001G1178	2.255e-104	348.0	COG0240@1|root,COG0240@2|Bacteria,2NP1N@2323|unclassified Bacteria	2|Bacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
YHH1_k127_10833861_11	349161.Dred_1161	2.593e-40	158.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,261ZE@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
YHH1_k127_1084594_0	690850.Desaf_0617	1.727e-149	494.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2M7U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
YHH1_k127_1084594_2	945713.IALB_1171	1.714e-60	221.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
YHH1_k127_1084594_1	945713.IALB_1170	3.698e-77	267.0	2E09V@1|root,32VXB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10877231_1	380394.Lferr_0216	4.653e-83	285.0	COG1484@1|root,COG1484@2|Bacteria,1NR77@1224|Proteobacteria	1224|Proteobacteria	L	PFAM IstB domain protein ATP-binding protein	MA20_45435	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
YHH1_k127_10877231_0	269482.Bcep1808_6140	1.002e-168	545.0	COG4584@1|root,COG4584@2|Bacteria,1MX20@1224|Proteobacteria,2VKGT@28216|Betaproteobacteria,1K6I1@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH1_k127_10877231_3	1304874.JAFY01000002_gene884	2.115e-32	128.0	COG3943@1|root,COG3943@2|Bacteria,3TC27@508458|Synergistetes	508458|Synergistetes	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
YHH1_k127_10877231_5	1140002.I570_00080	4.479e-07	58.0	2DCG6@1|root,2ZE0S@2|Bacteria,1U43E@1239|Firmicutes,4HHG9@91061|Bacilli,4B502@81852|Enterococcaceae	91061|Bacilli	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
YHH1_k127_10877231_2	767817.Desgi_1747	8.328e-46	175.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1,Y2_Tnp,Zn_Tnp_IS91
YHH1_k127_10877231_4	247490.KSU1_B0209	6.836e-30	123.0	COG4467@1|root,COG4467@2|Bacteria,2J4XJ@203682|Planctomycetes	203682|Planctomycetes	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,zf-IS66
YHH1_k127_10888562_1	261292.Nit79A3_1829	1.963e-145	474.0	COG4643@1|root,COG4643@2|Bacteria,1N08G@1224|Proteobacteria,2VPII@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3987
YHH1_k127_10888562_2	666509.RCA23_c22860	9.543e-18	84.0	COG3311@1|root,COG3311@2|Bacteria,1Q401@1224|Proteobacteria,2UKWR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Prophage CP4-57 regulatory protein (AlpA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_AlpA
YHH1_k127_10888562_0	292415.Tbd_2005	4.715e-231	720.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VHG5@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	intB	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
YHH1_k127_10916647_6	1232437.KL662077_gene1874	1.016e-18	86.0	arCOG10401@1|root,2ZA7Y@2|Bacteria,1R45R@1224|Proteobacteria,42MDG@68525|delta/epsilon subdivisions,2WKTC@28221|Deltaproteobacteria,2MIT0@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10916647_2	56780.SYN_00618	2.788e-89	301.0	COG2043@1|root,COG2043@2|Bacteria,1R8EH@1224|Proteobacteria,42Q2F@68525|delta/epsilon subdivisions,2WJZN@28221|Deltaproteobacteria,2MQKY@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
YHH1_k127_10916647_1	1267535.KB906767_gene1580	7.038e-136	441.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	MA20_17390	-	-	ko:K00713,ko:K06338	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_10916647_0	330214.NIDE3191	9.726e-267	840.0	COG3408@1|root,COG3408@2|Bacteria,3J0Z8@40117|Nitrospirae	40117|Nitrospirae	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
YHH1_k127_10916647_3	1125863.JAFN01000001_gene2317	8.246e-84	284.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
YHH1_k127_10916647_5	1123073.KB899242_gene932	1.224e-37	146.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1X3ZK@135614|Xanthomonadales	135614|Xanthomonadales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
YHH1_k127_10916647_4	349520.PPE_04870	1.857e-57	211.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,26QQA@186822|Paenibacillaceae	91061|Bacilli	C	NADH-dependent flavin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
YHH1_k127_10919610_1	756067.MicvaDRAFT_5030	6.685e-29	119.0	COG0724@1|root,COG0724@2|Bacteria,1G7Q7@1117|Cyanobacteria,1HBIK@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_10919610_3	1313304.CALK_1524	4.523e-17	85.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_10919610_0	880073.Calab_3220	1.299e-66	229.0	COG0450@1|root,COG0450@2|Bacteria,2NQYA@2323|unclassified Bacteria	2|Bacteria	O	C-terminal domain of 1-Cys peroxiredoxin	prxU	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
YHH1_k127_10919610_2	933262.AXAM01000078_gene1607	8.58e-26	108.0	COG0450@1|root,COG0450@2|Bacteria,1NBK9@1224|Proteobacteria,42VFJ@68525|delta/epsilon subdivisions,2WRB3@28221|Deltaproteobacteria,2MKWX@213118|Desulfobacterales	28221|Deltaproteobacteria	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH1_k127_10923090_8	517418.Ctha_0040	1.174e-24	110.0	COG0526@1|root,COG0526@2|Bacteria,1FE2F@1090|Chlorobi	1090|Chlorobi	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
YHH1_k127_10923090_0	1379698.RBG1_1C00001G1076	0.0	1393.0	COG3696@1|root,COG3696@2|Bacteria,2NP07@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
YHH1_k127_10923090_1	1379698.RBG1_1C00001G1075	3.429e-146	479.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
YHH1_k127_10923090_3	1157490.EL26_03360	3.088e-119	393.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
YHH1_k127_10923090_4	243231.GSU0012	3.73e-116	389.0	COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,42NBG@68525|delta/epsilon subdivisions,2WKMN@28221|Deltaproteobacteria,43SUB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemY	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
YHH1_k127_10923090_7	1232410.KI421415_gene3101	1.129e-71	254.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,43RXT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Ferrochelatase	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
YHH1_k127_10923090_2	224324.aq_2124	5.656e-130	430.0	COG0635@1|root,COG0635@2|Bacteria,2G4M1@200783|Aquificae	200783|Aquificae	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
YHH1_k127_10923090_6	653733.Selin_2337	5.472e-86	296.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
YHH1_k127_10923090_5	984262.SGRA_3721	7.742e-104	346.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1INWD@117747|Sphingobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH1_k127_10930717_0	626887.J057_16225	2.205e-77	263.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,1S5SK@1236|Gammaproteobacteria,468K2@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH1_k127_10930717_1	357804.Ping_0269	5.324e-31	124.0	2A022@1|root,30N4C@2|Bacteria,1PU9F@1224|Proteobacteria,1SCMU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1840)	VPA1132	-	-	-	-	-	-	-	-	-	-	-	DUF1840
YHH1_k127_10930717_2	1279015.KB908455_gene1271	1.169e-22	98.0	2E3KF@1|root,32YIQ@2|Bacteria,1NC3P@1224|Proteobacteria,1SD8X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10930717_6	1042156.CXIVA_10770	3.954e-07	53.0	COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,24AV5@186801|Clostridia,36ECJ@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	vanS	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA
YHH1_k127_10930717_3	1235457.C404_25970	6.597e-18	91.0	COG1422@1|root,COG1422@2|Bacteria,1NKWF@1224|Proteobacteria,2WFSV@28216|Betaproteobacteria,1KI5Q@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1090)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10930717_7	1220534.B655_1157	8.86e-06	48.0	arCOG02763@1|root,arCOG02763@2157|Archaea,2Y8CF@28890|Euryarchaeota,23PZN@183925|Methanobacteria	28890|Euryarchaeota	P	E1-E2 ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
YHH1_k127_10930717_4	1123514.KB905900_gene2162	7.969e-16	80.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZPW@72273|Thiotrichales	72273|Thiotrichales	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
YHH1_k127_10930717_5	1123073.KB899241_gene2407	1.116e-13	70.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,1SCQ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
YHH1_k127_10937309_4	479431.Namu_5321	7.934e-13	82.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria,4ES70@85013|Frankiales	201174|Actinobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
YHH1_k127_10937309_3	1179773.BN6_81490	2.184e-29	125.0	COG1595@1|root,COG1595@2|Bacteria,2IPV5@201174|Actinobacteria,4EF0Y@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
YHH1_k127_10937309_0	1254432.SCE1572_44870	1.069e-158	514.0	COG3104@1|root,COG3104@2|Bacteria,1P6K2@1224|Proteobacteria	1224|Proteobacteria	E	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH1_k127_10937309_1	4792.ETI51769	2.307e-85	295.0	COG0042@1|root,KOG2335@2759|Eukaryota,3QEGX@4776|Peronosporales	4776|Peronosporales	J	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs	-	-	-	-	-	-	-	-	-	-	-	-	Dus
YHH1_k127_10937309_2	323259.Mhun_2840	2.179e-69	247.0	COG3291@1|root,arCOG02516@1|root,arCOG03264@1|root,arCOG03606@1|root,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG03264@2157|Archaea,arCOG03606@2157|Archaea,2Y7RP@28890|Euryarchaeota,2NBKZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF3344,PKD
YHH1_k127_10937309_5	1123008.KB905712_gene761	1.268e-05	57.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,2FMXE@200643|Bacteroidia,22W6E@171551|Porphyromonadaceae	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wbpO	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH1_k127_10943780_0	1121405.dsmv_2347	1.169e-12	72.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2WJPG@28221|Deltaproteobacteria,2MI4A@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
YHH1_k127_10943780_2	204669.Acid345_4608	0.0001998	54.0	COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,3Y7E6@57723|Acidobacteria,2JMHJ@204432|Acidobacteriia	204432|Acidobacteriia	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
YHH1_k127_10943780_1	398720.MED217_10482	5.69e-06	59.0	28JUF@1|root,2Z9JH@2|Bacteria,4NHS3@976|Bacteroidetes,1HYHH@117743|Flavobacteriia,2XJ92@283735|Leeuwenhoekiella	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10994860_0	203122.Sde_3233	1.8e-73	267.0	COG0689@1|root,COG1357@1|root,COG1472@1|root,COG2931@1|root,COG0689@2|Bacteria,COG1357@2|Bacteria,COG1472@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,46D2S@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	psmE	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Cadherin_3,DUF4114,He_PIG,HemolysinCabind,Pectate_lyase_3,Peptidase_M10,Peptidase_M10_C
YHH1_k127_10996989_0	1123393.KB891316_gene1863	4.053e-120	391.0	COG5265@1|root,COG5265@2|Bacteria,1MWU5@1224|Proteobacteria,2VHDB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	HPr kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10996989_1	1266908.AQPB01000054_gene1747	1.603e-89	304.0	28JAH@1|root,2Z95A@2|Bacteria,1MXKT@1224|Proteobacteria,1RMX8@1236|Gammaproteobacteria,1WXXE@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
YHH1_k127_1135022_3	485916.Dtox_0071	3.366e-06	57.0	COG0308@1|root,COG0308@2|Bacteria,1V5S2@1239|Firmicutes,24HG5@186801|Clostridia,261WK@186807|Peptococcaceae	186801|Clostridia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
YHH1_k127_1135022_1	1379698.RBG1_1C00001G1514	5.673e-48	184.0	COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria	2|Bacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
YHH1_k127_1135022_2	234267.Acid_6486	2.745e-36	153.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
YHH1_k127_1135022_0	1499967.BAYZ01000019_gene6326	8.34e-93	320.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,2NP20@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	macB_1	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX,MacB_PCD
YHH1_k127_1135022_4	742727.HMPREF9447_03750	3.531e-06	57.0	COG1538@1|root,COG1538@2|Bacteria,4NGXM@976|Bacteroidetes,2FMD9@200643|Bacteroidia,4AKU0@815|Bacteroidaceae	976|Bacteroidetes	MU	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH1_k127_113964_0	1321778.HMPREF1982_00036	1.342e-237	738.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,26881@186813|unclassified Clostridiales	186801|Clostridia	EJ	Psort location Cytoplasmic, score	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
YHH1_k127_113964_2	688270.Celal_0837	1.43e-23	104.0	COG2827@1|root,COG2827@2|Bacteria,4NUYX@976|Bacteroidetes,1I4DQ@117743|Flavobacteriia,1FAET@104264|Cellulophaga	976|Bacteroidetes	L	T5orf172 domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH1_k127_113964_1	1123257.AUFV01000018_gene3691	4.09e-36	142.0	2DSM3@1|root,33GM1@2|Bacteria,1NPHW@1224|Proteobacteria	1224|Proteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
YHH1_k127_1190832_0	1379698.RBG1_1C00001G1491	2.44e-106	356.0	COG1420@1|root,COG1420@2|Bacteria,2NPAK@2323|unclassified Bacteria	2|Bacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA,HrcA_DNA-bdg
YHH1_k127_1190832_2	1379698.RBG1_1C00001G1490	3.027e-30	128.0	COG0576@1|root,COG0576@2|Bacteria,2NPSS@2323|unclassified Bacteria	2|Bacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YHH1_k127_1190832_1	1379698.RBG1_1C00001G1489	1.671e-92	306.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YHH1_k127_1208605_3	945713.IALB_0646	6.769e-10	59.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135	2.2.1.2,5.3.1.9	ko:K00616,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
YHH1_k127_1208605_0	429009.Adeg_0307	2.38e-149	485.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,42FJ7@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
YHH1_k127_1208605_1	177439.DP2771	8.857e-55	200.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,42QDS@68525|delta/epsilon subdivisions,2WMQ3@28221|Deltaproteobacteria,2MJQ8@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
YHH1_k127_1208605_2	1379698.RBG1_1C00001G1809	4.522e-49	179.0	COG1183@1|root,COG1183@2|Bacteria,2NPQM@2323|unclassified Bacteria	2|Bacteria	I	CDP-alcohol phosphatidyltransferase	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
YHH1_k127_1219677_1	679200.HMPREF9333_01919	2.501e-94	323.0	COG1032@1|root,COG1032@2|Bacteria,1TRZA@1239|Firmicutes,24B00@186801|Clostridia	186801|Clostridia	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YHH1_k127_1219677_0	1107311.Q767_10525	3.25e-135	445.0	COG1032@1|root,COG1032@2|Bacteria,4NFPW@976|Bacteroidetes,1INE4@117743|Flavobacteriia,2NZ97@237|Flavobacterium	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
YHH1_k127_1219677_2	1278073.MYSTI_04190	5.334e-68	245.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1219677_3	886377.Murru_2103	8.602e-21	103.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
YHH1_k127_1220042_0	1379698.RBG1_1C00001G1762	1.872e-121	408.0	COG3276@1|root,COG3276@2|Bacteria,2NNQU@2323|unclassified Bacteria	2|Bacteria	J	Elongation factor SelB, winged helix	selB	GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
YHH1_k127_1220042_1	667014.Thein_0419	9.684e-94	321.0	COG1921@1|root,COG1921@2|Bacteria,2GHB4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	SelA
YHH1_k127_1242955_3	747365.Thena_0079	1.424e-14	73.0	COG1484@1|root,COG1484@2|Bacteria,1TPPI@1239|Firmicutes,24DKZ@186801|Clostridia,42FBN@68295|Thermoanaerobacterales	186801|Clostridia	L	IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
YHH1_k127_1242955_1	1323663.AROI01000014_gene6	1.814e-71	258.0	COG4974@1|root,COG4974@2|Bacteria,1R72R@1224|Proteobacteria,1S8CW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH1_k127_1242955_0	1117958.PE143B_0100130	8.108e-77	271.0	COG0582@1|root,COG0582@2|Bacteria,1NX90@1224|Proteobacteria,1SDT1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YHH1_k127_1242955_2	234267.Acid_6799	9.831e-54	194.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH1_k127_1244630_10	1499967.BAYZ01000030_gene1194	2.487e-26	111.0	COG2827@1|root,COG2827@2|Bacteria,2NRAE@2323|unclassified Bacteria	2|Bacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH1_k127_1244630_3	1379698.RBG1_1C00001G0400	7.191e-123	409.0	COG0206@1|root,COG0206@2|Bacteria,2NNSU@2323|unclassified Bacteria	2|Bacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YHH1_k127_1244630_5	706587.Desti_4713	3.466e-115	386.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2MRBE@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
YHH1_k127_1244630_1	443143.GM18_3886	1.573e-143	469.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_1244630_8	1379698.RBG1_1C00001G0396	2.572e-75	276.0	COG0707@1|root,COG0707@2|Bacteria,2NP4Z@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	-	R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	GT28	iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Glyco_tran_28_C,Glyco_transf_28
YHH1_k127_1244630_6	1379698.RBG1_1C00001G0395	2.833e-90	309.0	COG0772@1|root,COG0772@2|Bacteria,2NP3P@2323|unclassified Bacteria	2|Bacteria	D	Belongs to the SEDS family	ftsW	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
YHH1_k127_1244630_4	945713.IALB_2208	5.777e-118	395.0	COG0771@1|root,COG0771@2|Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH1_k127_1244630_0	1379698.RBG1_1C00001G0393	8.228e-150	481.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
YHH1_k127_1244630_7	1033734.CAET01000079_gene3573	9.541e-88	306.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,1ZCC3@1386|Bacillus	91061|Bacilli	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_1244630_2	644966.Tmar_0865	7.716e-126	420.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WCXE@538999|Clostridiales incertae sedis	186801|Clostridia	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_1244630_9	517418.Ctha_0827	3.696e-70	256.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1FDDH@1090|Chlorobi	1090|Chlorobi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
YHH1_k127_1252349_1	234267.Acid_7188	2.531e-20	93.0	COG2844@1|root,COG2844@2|Bacteria,3Y2FJ@57723|Acidobacteria	57723|Acidobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
YHH1_k127_1252349_0	1121456.ATVA01000017_gene97	2.151e-132	434.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,43AN9@68525|delta/epsilon subdivisions,2WJH6@28221|Deltaproteobacteria,2MG99@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH1_k127_1252349_2	589865.DaAHT2_0817	0.0001055	55.0	COG0457@1|root,COG0457@2|Bacteria,1N0Q1@1224|Proteobacteria,42TBT@68525|delta/epsilon subdivisions,2WQ96@28221|Deltaproteobacteria,2MK73@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
YHH1_k127_1265355_2	1444309.JAQG01000005_gene4339	1.725e-58	212.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,26TNF@186822|Paenibacillaceae	91061|Bacilli	C	NAD(P)H-dependent oxidoreductase	nfrA	-	1.5.1.38	ko:K10678,ko:K19285	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	-	R05706,R08014,R08017,R08042	RC00126,RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
YHH1_k127_1265355_1	525897.Dbac_0464	1.814e-92	313.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2WK5J@28221|Deltaproteobacteria,2M9C6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH1_k127_1265355_0	720554.Clocl_1150	5.241e-136	443.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,3WGG1@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
YHH1_k127_1311259_2	459349.CLOAM0028	4.401e-26	112.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1311259_0	1379698.RBG1_1C00001G0884	1.092e-102	347.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K02027,ko:K17329	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
YHH1_k127_1311259_1	1379698.RBG1_1C00001G0883	3.735e-76	263.0	COG1175@1|root,COG1175@2|Bacteria,2NPDA@2323|unclassified Bacteria	2|Bacteria	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
YHH1_k127_1326480_0	177439.DP1513	1.533e-109	364.0	2C1K7@1|root,2ZA9X@2|Bacteria,1R95T@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1326480_1	1530186.JQEY01000026_gene1808	6.473e-86	285.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TRDG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K15552	ko00920,ko02010,map00920,map02010	M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
YHH1_k127_1327555_4	946483.Cenrod_0663	5.694e-10	61.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,4A9Q7@80864|Comamonadaceae	28216|Betaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
YHH1_k127_1327555_2	1158318.ATXC01000001_gene1441	2.643e-87	294.0	COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae	200783|Aquificae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YHH1_k127_1327555_3	1379698.RBG1_1C00001G1716	2.085e-75	269.0	COG0544@1|root,COG0544@2|Bacteria,2NPBN@2323|unclassified Bacteria	2|Bacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YHH1_k127_1327555_0	378806.STAUR_6676	4.676e-160	510.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YXF2@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
YHH1_k127_1327555_1	237368.SCABRO_00906	1.244e-102	357.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_1327555_6	247490.KSU1_D0861	3.592e-06	52.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_1367366_2	876044.IMCC3088_699	0.000158	45.0	COG0399@1|root,COG0399@2|Bacteria,1N3NC@1224|Proteobacteria,1SAHP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
YHH1_k127_1367366_1	43989.cce_0692	6.78e-45	168.0	COG1246@1|root,COG1246@2|Bacteria,1GQ6C@1117|Cyanobacteria	1117|Cyanobacteria	E	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
YHH1_k127_1367366_0	1380391.JIAS01000011_gene5122	8.137e-127	422.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,2JR1T@204441|Rhodospirillales	204441|Rhodospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_19
YHH1_k127_1371278_2	1120953.AUBH01000001_gene978	1.456e-32	137.0	COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,4666U@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,PPC,Peptidase_S8
YHH1_k127_1371278_0	1163617.SCD_n01065	1.972e-39	154.0	2EBX9@1|root,335WM@2|Bacteria,1NCDM@1224|Proteobacteria,2VYXB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1371278_1	1122243.KB903793_gene1762	5.015e-36	150.0	COG3594@1|root,COG3594@2|Bacteria,1ND38@1224|Proteobacteria,1SHJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
YHH1_k127_1371278_3	1265505.ATUG01000001_gene4448	2.236e-23	100.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria,2MMU3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
YHH1_k127_1371278_5	314278.NB231_09628	4.554e-14	74.0	COG0476@1|root,COG0778@1|root,COG0476@2|Bacteria,COG0778@2|Bacteria,1QUMS@1224|Proteobacteria,1T2UN@1236|Gammaproteobacteria,1WWZY@135613|Chromatiales	135613|Chromatiales	H	UBA THIF-type NAD FAD binding	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,ThiF
YHH1_k127_1371278_6	314278.NB231_09628	0.0006968	44.0	COG0476@1|root,COG0778@1|root,COG0476@2|Bacteria,COG0778@2|Bacteria,1QUMS@1224|Proteobacteria,1T2UN@1236|Gammaproteobacteria,1WWZY@135613|Chromatiales	135613|Chromatiales	H	UBA THIF-type NAD FAD binding	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,ThiF
YHH1_k127_1371278_4	314278.NB231_09588	4.512e-22	98.0	COG0399@1|root,COG0399@2|Bacteria,1N3NC@1224|Proteobacteria,1SAHP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
YHH1_k127_1386874_11	1396141.BATP01000004_gene5898	2.894e-32	130.0	COG1793@1|root,COG1793@2|Bacteria,46TK9@74201|Verrucomicrobia,2IV60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH1_k127_1386874_10	522772.Dacet_0991	6.706e-46	168.0	COG1943@1|root,COG1943@2|Bacteria,2GGJ9@200930|Deferribacteres	200930|Deferribacteres	L	to the N-terminal region of	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH1_k127_1386874_7	945713.IALB_1084	2.087e-74	276.0	COG2843@1|root,COG2931@1|root,COG2843@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	capA	-	-	ko:K06990,ko:K07282	-	-	-	-	ko00000,ko04812	-	-	-	Memo,PGA_cap
YHH1_k127_1386874_3	880072.Desac_2636	2.692e-101	334.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_1386874_0	1232410.KI421421_gene3404	1.233e-174	566.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43SD2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like
YHH1_k127_1386874_8	215803.DB30_0085	4.127e-50	195.0	COG3746@1|root,COG3746@2|Bacteria,1PBWD@1224|Proteobacteria,433TT@68525|delta/epsilon subdivisions,2X3F8@28221|Deltaproteobacteria,2YVU2@29|Myxococcales	28221|Deltaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1386874_5	1131812.JQMS01000001_gene1238	2.147e-82	283.0	COG0226@1|root,COG0226@2|Bacteria,4NJGR@976|Bacteroidetes,1I2BC@117743|Flavobacteriia,2NTPT@237|Flavobacterium	976|Bacteroidetes	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
YHH1_k127_1386874_4	378806.STAUR_5630	4.492e-97	327.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YHH1_k127_1386874_2	378806.STAUR_5631	6.903e-109	362.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
YHH1_k127_1386874_1	526222.Desal_3392	2.36e-109	359.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,2M7VZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
YHH1_k127_1386874_6	1499967.BAYZ01000068_gene1924	4.882e-75	258.0	COG0704@1|root,COG0704@2|Bacteria,2NPWX@2323|unclassified Bacteria	2|Bacteria	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
YHH1_k127_1386874_9	880073.Calab_2422	5.164e-48	183.0	COG1449@1|root,COG1449@2|Bacteria,2NQNB@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
YHH1_k127_1389537_0	926569.ANT_19030	7.397e-48	174.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
YHH1_k127_1389537_1	926569.ANT_19040	1.312e-29	121.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1416653_0	1380763.BG53_03300	2.345e-153	499.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,26TDB@186822|Paenibacillaceae	91061|Bacilli	I	catalyzes the conversion of acetate and CoA to acetyl-CoA	acsA_1	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
YHH1_k127_1416653_5	269799.Gmet_1884	5.144e-11	68.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria,43VJF@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
YHH1_k127_1416653_1	526227.Mesil_2958	1.068e-135	438.0	COG0451@1|root,COG0451@2|Bacteria,1WNCR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.203	ko:K18981	ko00053,map00053	-	R10841	RC00066	ko00000,ko00001,ko01000	-	-	-	Epimerase
YHH1_k127_1416653_4	1340493.JNIF01000003_gene1954	1.219e-19	96.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_16815	-	-	-	-	-	-	-	-	-	-	-	TetR_N
YHH1_k127_1416653_2	243231.GSU2203	4.885e-81	280.0	COG3005@1|root,COG3005@2|Bacteria,1RHMA@1224|Proteobacteria,43DN4@68525|delta/epsilon subdivisions,2X6GA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YHH1_k127_1416653_3	243231.GSU2204	2.354e-22	112.0	2AJX3@1|root,31AK2@2|Bacteria,1NWRV@1224|Proteobacteria,4300K@68525|delta/epsilon subdivisions,2WVGP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
YHH1_k127_1445400_3	1379698.RBG1_1C00001G1750	2.585e-85	296.0	COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
YHH1_k127_1445400_6	1379698.RBG1_1C00001G1748	6.702e-47	179.0	COG0457@1|root,COG0457@2|Bacteria,2NS1B@2323|unclassified Bacteria	2|Bacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1445400_7	1379698.RBG1_1C00001G1746	1.976e-37	144.0	COG2018@1|root,COG2018@2|Bacteria,2NRUR@2323|unclassified Bacteria	2|Bacteria	S	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
YHH1_k127_1445400_4	1379698.RBG1_1C00001G1745	4.756e-84	290.0	COG1100@1|root,COG1100@2|Bacteria,2NPDD@2323|unclassified Bacteria	2|Bacteria	K	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
YHH1_k127_1445400_5	1379698.RBG1_1C00001G1744	9.594e-66	228.0	COG2018@1|root,COG2018@2|Bacteria,2NQXH@2323|unclassified Bacteria	2|Bacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
YHH1_k127_1445400_0	944479.JQLX01000010_gene642	4.652e-175	565.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
YHH1_k127_1445400_1	1379698.RBG1_1C00001G1742	5.183e-162	516.0	COG2805@1|root,COG2805@2|Bacteria,2NNR7@2323|unclassified Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH1_k127_1445400_2	1379698.RBG1_1C00001G1741	1.592e-104	345.0	COG1459@1|root,COG1459@2|Bacteria,2NP2J@2323|unclassified Bacteria	2|Bacteria	U	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH1_k127_1470905_8	28583.AMAG_13900T0	4.957e-24	117.0	COG0666@1|root,KOG4412@2759|Eukaryota,39VDP@33154|Opisthokonta,3NXYE@4751|Fungi	4751|Fungi	O	Proteasome regulatory particle	NAS6	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0019538,GO:0022607,GO:0032991,GO:0034622,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043248,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070682,GO:0071704,GO:0071840,GO:1901564	-	ko:K06694	-	-	-	-	ko00000,ko03051	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
YHH1_k127_1470905_7	1047013.AQSP01000053_gene289	2.89e-27	128.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH1_k127_1470905_3	1167006.UWK_01462	1.275e-86	294.0	COG2084@1|root,COG2084@2|Bacteria,1PHRJ@1224|Proteobacteria,4348T@68525|delta/epsilon subdivisions,2X9TJ@28221|Deltaproteobacteria,2MNX7@213118|Desulfobacterales	28221|Deltaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
YHH1_k127_1470905_0	1121920.AUAU01000012_gene2677	4.488e-188	603.0	COG0281@1|root,COG0281@2|Bacteria,3Y43V@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
YHH1_k127_1470905_1	42256.RradSPS_1129	1.39e-155	503.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CPEU@84995|Rubrobacteria	84995|Rubrobacteria	G	alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YHH1_k127_1470905_9	867900.Celly_1159	2.402e-23	109.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia,1F8TS@104264|Cellulophaga	976|Bacteroidetes	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_1470905_2	525904.Tter_0096	6.365e-98	328.0	COG0320@1|root,COG0320@2|Bacteria,2NNPI@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
YHH1_k127_1470905_4	1125863.JAFN01000001_gene3034	2.811e-82	292.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HD,Response_reg
YHH1_k127_1470905_5	1379698.RBG1_1C00001G1090	1.498e-58	218.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
YHH1_k127_1470905_6	1379698.RBG1_1C00001G1267	2.254e-42	173.0	COG0419@1|root,COG0419@2|Bacteria,2NPX7@2323|unclassified Bacteria	2|Bacteria	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SMC_N,SbcCD_C
YHH1_k127_1480551_2	203275.BFO_2717	5.436e-12	67.0	28KQH@1|root,2ZA8A@2|Bacteria	2|Bacteria	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
YHH1_k127_1480551_0	1047013.AQSP01000130_gene1864	3.244e-210	664.0	COG0591@1|root,COG0591@2|Bacteria,2NPAX@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
YHH1_k127_1480551_1	1408473.JHXO01000008_gene2646	1.932e-158	521.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,4PKNJ@976|Bacteroidetes,2FUXF@200643|Bacteroidia	976|Bacteroidetes	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_8,PAS_9
YHH1_k127_155242_6	755732.Fluta_0838	1.663e-22	100.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia,2PAMB@246874|Cryomorphaceae	976|Bacteroidetes	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
YHH1_k127_155242_3	1226322.HMPREF1545_04263	6.634e-80	274.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,2N6V1@216572|Oscillospiraceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH1_k127_155242_5	1379698.RBG1_1C00001G1825	9.688e-28	113.0	COG0236@1|root,COG0236@2|Bacteria,2NPVJ@2323|unclassified Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
YHH1_k127_155242_0	1379698.RBG1_1C00001G1824	1.241e-185	588.0	COG0304@1|root,COG0304@2|Bacteria,2NNSX@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
YHH1_k127_155242_4	1379698.RBG1_1C00001G1823	1.468e-66	234.0	COG0571@1|root,COG0571@2|Bacteria,2NPCJ@2323|unclassified Bacteria	2|Bacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YHH1_k127_155242_1	1379698.RBG1_1C00001G0527	6.608e-167	533.0	COG1960@1|root,COG1960@2|Bacteria,2NNXA@2323|unclassified Bacteria	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YHH1_k127_155242_7	697329.Rumal_2962	7.687e-06	54.0	COG1670@1|root,COG1670@2|Bacteria,1V4F3@1239|Firmicutes,24EZ6@186801|Clostridia,3WM79@541000|Ruminococcaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
YHH1_k127_155242_2	1449126.JQKL01000031_gene1144	4.926e-81	277.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,267WS@186813|unclassified Clostridiales	186801|Clostridia	I	Enoyl-CoA hydratase/isomerase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
YHH1_k127_15543_4	1379698.RBG1_1C00001G1524	4.201e-53	205.0	COG2911@1|root,COG2911@2|Bacteria,2NQ89@2323|unclassified Bacteria	2|Bacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K07277,ko:K09800	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	AsmA_2,DUF748,TamB
YHH1_k127_15543_2	1379698.RBG1_1C00001G1523	1.713e-86	310.0	COG4775@1|root,COG4775@2|Bacteria,2NQXR@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YHH1_k127_15543_0	246194.CHY_2199	1.493e-130	428.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YHH1_k127_15543_1	880073.Calab_1731	8.133e-115	380.0	COG0482@1|root,COG0482@2|Bacteria,2NNPW@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
YHH1_k127_15543_3	1125863.JAFN01000001_gene1105	5.427e-80	272.0	COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,42Q5T@68525|delta/epsilon subdivisions,2WKN4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
YHH1_k127_15543_5	557598.LHK_01473	7.279e-05	50.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,2KR0J@206351|Neisseriales	206351|Neisseriales	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
YHH1_k127_1556453_1	926569.ANT_30920	1.254e-66	236.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	dppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YHH1_k127_1556453_0	926569.ANT_29620	3.577e-127	411.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
YHH1_k127_1573504_0	1379698.RBG1_1C00001G1194	5.035e-30	130.0	COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	3.2.1.91	ko:K14194,ko:K19668	ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CHU_C,DUF11,FlgD_ig,PKD,SdrD_B
YHH1_k127_1586668_1	1183438.GKIL_0191	4.197e-28	117.0	COG1293@1|root,COG1293@2|Bacteria,1G01H@1117|Cyanobacteria	1117|Cyanobacteria	K	RNA-binding protein homologous to eukaryotic snRNP	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
YHH1_k127_1586668_0	1396418.BATQ01000056_gene181	4.117e-51	195.0	COG4188@1|root,COG4188@2|Bacteria,46TTD@74201|Verrucomicrobia,2IVPV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
YHH1_k127_1586668_2	1484479.DI14_12905	3.312e-13	75.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,3WE6M@539002|Bacillales incertae sedis	91061|Bacilli	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,Oxidored_FMN
YHH1_k127_1609867_0	795359.TOPB45_1257	3.342e-179	576.0	COG0174@1|root,COG0174@2|Bacteria,2GH5N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YHH1_k127_1609867_1	1121382.JQKG01000025_gene2998	3.15e-12	70.0	COG0154@1|root,COG0154@2|Bacteria,1WIG3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH1_k127_1615780_1	1379698.RBG1_1C00001G0117	1.143e-75	259.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1615780_0	1379698.RBG1_1C00001G0116	4.742e-76	261.0	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1615780_2	1379698.RBG1_1C00001G0119	6.379e-38	151.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1629132_9	1227739.Hsw_3777	0.0004832	49.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	MA20_05910	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META
YHH1_k127_1629132_7	570952.ATVH01000015_gene1531	7.463e-11	72.0	COG3650@1|root,COG3650@2|Bacteria	2|Bacteria	CO	response to hydrogen peroxide	-	-	-	ko:K08985	-	-	-	-	ko00000	-	-	-	-
YHH1_k127_1629132_8	1577887.JSYG01000026_gene350	2.264e-07	57.0	COG3895@1|root,COG3895@2|Bacteria,1N4BY@1224|Proteobacteria,1S9UV@1236|Gammaproteobacteria,2JECD@204037|Dickeya	1236|Gammaproteobacteria	M	Membrane-bound lysozyme-inhibitor of c-type lysozyme	mliC	-	-	-	-	-	-	-	-	-	-	-	MliC
YHH1_k127_1629132_2	234267.Acid_7679	2.03e-66	251.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YHH1_k127_1629132_1	1304885.AUEY01000001_gene3203	3.583e-68	238.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
YHH1_k127_1629132_4	1304885.AUEY01000001_gene3204	1.412e-27	117.0	2DPAK@1|root,33193@2|Bacteria,1NDU6@1224|Proteobacteria,432ZD@68525|delta/epsilon subdivisions,2WYIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1629132_6	580340.Tlie_0329	9.058e-19	88.0	COG0526@1|root,COG0526@2|Bacteria,3TBM2@508458|Synergistetes	508458|Synergistetes	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
YHH1_k127_1629132_0	1499967.BAYZ01000050_gene2840	3.121e-194	614.0	COG0701@1|root,COG0701@2|Bacteria,2NP6A@2323|unclassified Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
YHH1_k127_1629132_3	1499967.BAYZ01000050_gene2839	1.28e-38	146.0	COG0640@1|root,COG0640@2|Bacteria,2NQ13@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	3.6.4.12	ko:K03655,ko:K03892	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	HTH_20,HTH_5
YHH1_k127_1635937_3	986075.CathTA2_0863	7.597e-58	211.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,4HB6B@91061|Bacilli	91061|Bacilli	J	metal-dependent phosphoesterases (PHP family)	php	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
YHH1_k127_1635937_0	1379698.RBG1_1C00001G1247	1.158e-165	535.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
YHH1_k127_1635937_1	1379698.RBG1_1C00001G1248	4.643e-89	303.0	COG1899@1|root,COG1899@2|Bacteria,2NP1S@2323|unclassified Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1635937_2	1379698.RBG1_1C00001G1249	1.402e-74	259.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
YHH1_k127_1635937_5	935948.KE386494_gene822	4.442e-29	122.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YHH1_k127_1635937_6	224325.AF_0781	2.626e-26	118.0	COG0009@1|root,arCOG01952@2157|Archaea,2XVGC@28890|Euryarchaeota,245ZQ@183980|Archaeoglobi	183980|Archaeoglobi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
YHH1_k127_1635937_4	1379698.RBG1_1C00001G1252	4.838e-57	203.0	COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria	2|Bacteria	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8,5.4.2.8	ko:K00971,ko:K01840,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01818,R01819	RC00002,RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00940	MannoseP_isomer,NTP_transferase
YHH1_k127_1643070_5	309807.SRU_2609	2.66e-30	127.0	COG1843@1|root,COG1843@2|Bacteria,4PF6J@976|Bacteroidetes,1FK7T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	N	Required for flagellar hook formation. May act as a scaffolding protein	-	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD,FlgD_ig
YHH1_k127_1643070_7	644282.Deba_2305	6.901e-06	59.0	COG3144@1|root,COG3144@2|Bacteria	2|Bacteria	N	bacterial-type flagellum assembly	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
YHH1_k127_1643070_8	1536773.R70331_18505	0.0008446	50.0	COG3334@1|root,COG3334@2|Bacteria,1V87H@1239|Firmicutes,4HJU9@91061|Bacilli,26RXM@186822|Paenibacillaceae	91061|Bacilli	S	MgtE intracellular N domain	ylxF	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
YHH1_k127_1643070_0	278963.ATWD01000001_gene3395	6.834e-200	637.0	COG0504@1|root,COG0504@2|Bacteria,3Y2MH@57723|Acidobacteria,2JID4@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
YHH1_k127_1643070_3	243231.GSU1896	1.657e-50	189.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43T2I@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
YHH1_k127_1643070_6	648996.Theam_1648	4.721e-23	101.0	COG0721@1|root,COG0721@2|Bacteria,2G4A2@200783|Aquificae	200783|Aquificae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
YHH1_k127_1643070_1	237368.SCABRO_02014	2.078e-109	370.0	COG2204@1|root,COG2204@2|Bacteria,2IYIG@203682|Planctomycetes	203682|Planctomycetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_1643070_2	1379698.RBG1_1C00001G0988	3.736e-65	246.0	COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria	2|Bacteria	C	lyase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
YHH1_k127_1643070_4	1379698.RBG1_1C00001G0519	1.811e-46	179.0	COG0697@1|root,COG0697@2|Bacteria,2NPZZ@2323|unclassified Bacteria	2|Bacteria	EG	EamA-like transporter family	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
YHH1_k127_1664274_3	910314.HMPREF9220_1181	0.0003777	51.0	COG1538@1|root,COG1538@2|Bacteria,1TRDS@1239|Firmicutes,4H2S7@909932|Negativicutes	909932|Negativicutes	MU	outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH1_k127_1664274_0	1121405.dsmv_0518	1.119e-46	181.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,2MIGM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM lipopolysaccharide heptosyltransferase II	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH1_k127_1664274_4	1284708.HMPREF1634_01770	0.0005673	46.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,24JAB@186801|Clostridia,3WCNU@538999|Clostridiales incertae sedis	186801|Clostridia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
YHH1_k127_1664274_1	1379698.RBG1_1C00001G1508	1.881e-33	132.0	2E4KV@1|root,32ZFU@2|Bacteria,2NQ0D@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
YHH1_k127_1664274_2	1379698.RBG1_1C00001G1507	2.723e-26	111.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
YHH1_k127_167969_2	313596.RB2501_04710	1.359e-17	85.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
YHH1_k127_167969_0	261292.Nit79A3_0035	1.035e-179	573.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2VHRC@28216|Betaproteobacteria,3726I@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
YHH1_k127_167969_1	1232410.KI421421_gene3337	7.632e-28	116.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42YBV@68525|delta/epsilon subdivisions,2WTTU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
YHH1_k127_167969_3	909663.KI867150_gene1245	3.056e-06	49.0	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MR1B@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA binding domain	acs	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
YHH1_k127_1690073_7	880073.Calab_3127	1.327e-09	70.0	2C4MF@1|root,300D5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1690073_5	1123288.SOV_5c05070	1.109e-49	190.0	COG2378@1|root,COG2378@2|Bacteria,1TS78@1239|Firmicutes,4H45V@909932|Negativicutes	909932|Negativicutes	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
YHH1_k127_1690073_8	1123399.AQVE01000019_gene1630	1.471e-06	58.0	COG2378@1|root,COG2378@2|Bacteria,1MXS8@1224|Proteobacteria,1RYN3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
YHH1_k127_1690073_6	443254.Marpi_1888	1.091e-39	153.0	COG4708@1|root,COG4708@2|Bacteria,2GE32@200918|Thermotogae	200918|Thermotogae	S	QueT transporter	-	-	-	-	-	-	-	-	-	-	-	-	QueT
YHH1_k127_1690073_4	375286.mma_1306	9.276e-51	188.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,2VKF1@28216|Betaproteobacteria,472Y8@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
YHH1_k127_1690073_1	1444712.BN1013_00669	4.65e-128	417.0	COG0306@1|root,COG0306@2|Bacteria,2JH20@204428|Chlamydiae	204428|Chlamydiae	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
YHH1_k127_1690073_2	880072.Desac_2642	6.046e-64	226.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,2MSIW@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
YHH1_k127_1690073_0	1319815.HMPREF0202_01332	4.666e-138	448.0	COG2309@1|root,COG2309@2|Bacteria,379GR@32066|Fusobacteria	32066|Fusobacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
YHH1_k127_1690073_3	1121406.JAEX01000005_gene3115	1.091e-54	196.0	COG0835@1|root,COG0835@2|Bacteria,1RG4A@1224|Proteobacteria,43AIK@68525|delta/epsilon subdivisions,2X5YT@28221|Deltaproteobacteria,2MGWV@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	cheW64H-1	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
YHH1_k127_1690700_3	945713.IALB_1372	4.792e-20	98.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y
YHH1_k127_1690700_0	1379698.RBG1_1C00001G1786	3.962e-30	131.0	2CUTJ@1|root,32SW3@2|Bacteria,2NRD1@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1690700_2	1191523.MROS_1802	5.981e-22	105.0	2EAWV@1|root,334Y2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1690700_1	521011.Mpal_1345	2.081e-26	121.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
YHH1_k127_1690700_4	1379698.RBG1_1C00001G1783	4.737e-05	53.0	COG5448@1|root,COG5448@2|Bacteria,2NPPC@2323|unclassified Bacteria	2|Bacteria	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
YHH1_k127_1702824_5	755732.Fluta_2830	1.565e-56	213.0	COG2885@1|root,COG2885@2|Bacteria,4NI3U@976|Bacteroidetes,1I04E@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
YHH1_k127_1702824_3	686340.Metal_0160	4.549e-79	272.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1XEHN@135618|Methylococcales	135618|Methylococcales	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
YHH1_k127_1702824_2	880073.Calab_2557	6.224e-94	325.0	COG0477@1|root,COG2814@2|Bacteria,2NS3M@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	bacE	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
YHH1_k127_1702824_7	530564.Psta_3588	9.676e-42	158.0	COG0817@1|root,COG0817@2|Bacteria,2IZJS@203682|Planctomycetes	203682|Planctomycetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
YHH1_k127_1702824_8	886293.Sinac_2866	1.281e-28	123.0	COG0632@1|root,COG0632@2|Bacteria,2IZ2E@203682|Planctomycetes	203682|Planctomycetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
YHH1_k127_1702824_0	1485544.JQKP01000014_gene1867	1.924e-121	398.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,44VJD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YHH1_k127_1702824_9	639282.DEFDS_1432	2.499e-19	89.0	2DNS1@1|root,32YVX@2|Bacteria,2GG1X@200930|Deferribacteres	200930|Deferribacteres	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
YHH1_k127_1702824_1	648996.Theam_1729	3.557e-104	348.0	COG0809@1|root,COG0809@2|Bacteria,2G3KG@200783|Aquificae	200783|Aquificae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
YHH1_k127_1702824_6	868595.Desca_0181	9.633e-47	177.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,261YY@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
YHH1_k127_1702824_4	1158612.I580_02443	1.054e-57	205.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,4HG1X@91061|Bacilli,4B1HQ@81852|Enterococcaceae	91061|Bacilli	F	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
YHH1_k127_1702824_10	1121019.AUMN01000006_gene2962	0.000213	46.0	COG0586@1|root,COG0586@2|Bacteria,2HKKQ@201174|Actinobacteria,1W9GU@1268|Micrococcaceae	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH1_k127_1723020_2	1379698.RBG1_1C00001G1676	2.152e-138	443.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,2NPBE@2323|unclassified Bacteria	2|Bacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
YHH1_k127_1723020_1	373903.Hore_09670	6.369e-201	651.0	COG4953@1|root,COG4953@2|Bacteria	2|Bacteria	M	penicillin binding	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
YHH1_k127_1723020_0	373903.Hore_09660	5.747e-289	930.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
YHH1_k127_1726533_0	373903.Hore_21200	9.291e-265	854.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3WA6U@53433|Halanaerobiales	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
YHH1_k127_1726533_3	671143.DAMO_1765	3.098e-55	203.0	COG1360@1|root,COG1360@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
YHH1_k127_1726533_2	1303518.CCALI_00726	1.03e-84	291.0	COG1291@1|root,COG1291@2|Bacteria	2|Bacteria	N	archaeal or bacterial-type flagellum-dependent cell motility	motA	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
YHH1_k127_1726533_1	1123242.JH636435_gene2052	2.523e-122	407.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YHH1_k127_1754048_1	1379698.RBG1_1C00001G0347	1.69e-74	257.0	COG1657@1|root,COG1657@2|Bacteria,2NP7R@2323|unclassified Bacteria	2|Bacteria	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159,Prenyltrans
YHH1_k127_1754048_0	1379698.RBG1_1C00001G0350	6.691e-174	587.0	COG1196@1|root,COG1196@2|Bacteria,2NNSS@2323|unclassified Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1754048_4	1121104.AQXH01000001_gene1421	4.483e-15	89.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1INS7@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
YHH1_k127_1754048_2	1379698.RBG1_1C00001G0356	5.643e-53	198.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
YHH1_k127_1758750_1	754027.HMPREF9554_00367	1.915e-08	55.0	COG1898@1|root,COG1898@2|Bacteria,2J65Y@203691|Spirochaetes	203691|Spirochaetes	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
YHH1_k127_1758750_2	99598.Cal7507_0193	6.658e-06	50.0	COG1872@1|root,COG1872@2|Bacteria,1G935@1117|Cyanobacteria,1HPRR@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
YHH1_k127_1758750_0	1125863.JAFN01000001_gene71	1.153e-31	142.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
YHH1_k127_1770325_3	1089550.ATTH01000001_gene1568	3.324e-31	127.0	2AB6K@1|root,310KX@2|Bacteria,4PF76@976|Bacteroidetes,1FK8M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1770325_1	1379698.RBG1_1C00001G0223	1.547e-81	281.0	COG0284@1|root,COG0284@2|Bacteria,2NP92@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
YHH1_k127_1770325_0	1232410.KI421414_gene2892	2.714e-93	315.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,43S1B@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Dihydroorotate dehydrogenase	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YHH1_k127_1770325_2	1125863.JAFN01000001_gene358	1.259e-34	137.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
YHH1_k127_1770515_2	309801.trd_0848	9.24e-05	48.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi,27YPB@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
YHH1_k127_1770515_0	459349.CLOAM0099	1.909e-65	253.0	COG2234@1|root,COG2234@2|Bacteria,2NQ2F@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M28	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
YHH1_k127_1770515_1	1379698.RBG1_1C00001G0964	6.071e-25	108.0	COG2050@1|root,COG2050@2|Bacteria,2NQ0Q@2323|unclassified Bacteria	2|Bacteria	Q	Thioesterase superfamily	-	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
YHH1_k127_1811165_3	945713.IALB_0488	4.913e-06	56.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
YHH1_k127_1811165_1	880073.Calab_0181	3.661e-19	99.0	COG2067@1|root,COG2067@2|Bacteria,2NRFG@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1811165_0	1379698.RBG1_1C00001G0488	1.747e-22	114.0	COG4447@1|root,COG4447@2|Bacteria,2NRAH@2323|unclassified Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cu_amine_oxidN1,F5_F8_type_C
YHH1_k127_1811165_2	684949.ATTJ01000001_gene843	2.799e-14	82.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
YHH1_k127_1836143_3	1487956.DR71_1504	9.013e-20	91.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,22JTK@1653|Corynebacteriaceae	201174|Actinobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
YHH1_k127_1836143_0	1379698.RBG1_1C00001G0198	2.212e-49	190.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YHH1_k127_1836143_2	263358.VAB18032_25000	5.725e-23	105.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4DF59@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
YHH1_k127_1836143_1	234267.Acid_3454	2.224e-39	169.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y7SH@57723|Acidobacteria	57723|Acidobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
YHH1_k127_1836143_4	1121382.JQKG01000046_gene1373	3.254e-17	91.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,TIG
YHH1_k127_1858806_1	1121272.KB903252_gene1086	4.47e-09	64.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4DCZN@85008|Micromonosporales	201174|Actinobacteria	K	transcriptional regulator, Rrf2 family	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
YHH1_k127_1858806_0	945713.IALB_2283	5.759e-122	403.0	COG0653@1|root,COG0653@2|Bacteria	2|Bacteria	U	protein targeting	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH1_k127_1870741_6	1089550.ATTH01000001_gene1005	1.817e-24	121.0	COG1404@1|root,COG3591@1|root,COG4932@1|root,COG1404@2|Bacteria,COG3591@2|Bacteria,COG4932@2|Bacteria,4NG2K@976|Bacteroidetes,1FJTD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EO	Trypsin-like serine protease	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Trypsin_2
YHH1_k127_1870741_8	1236976.JCM16418_1910	9.866e-21	108.0	COG3325@1|root,COG4733@1|root,COG3325@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CBM_6,DUF1906,Glyco_hydro_81,Peptidase_S8,fn3
YHH1_k127_1870741_2	682795.AciX8_4212	1.571e-122	402.0	COG0309@1|root,COG0309@2|Bacteria,3Y3UH@57723|Acidobacteria,2JK96@204432|Acidobacteriia	204432|Acidobacteriia	O	AIR synthase related protein, C-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
YHH1_k127_1870741_1	517418.Ctha_1826	3.956e-177	561.0	COG0409@1|root,COG0409@2|Bacteria,1FD8B@1090|Chlorobi	1090|Chlorobi	O	hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
YHH1_k127_1870741_5	290317.Cpha266_0723	1.245e-24	107.0	COG0298@1|root,COG0298@2|Bacteria,1FE7S@1090|Chlorobi	1090|Chlorobi	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
YHH1_k127_1870741_0	517418.Ctha_1151	4.146e-237	756.0	COG0068@1|root,COG0068@2|Bacteria,1FDST@1090|Chlorobi	1090|Chlorobi	O	Belongs to the carbamoyltransferase HypF family	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
YHH1_k127_1870741_3	1121459.AQXE01000008_gene772	1.335e-68	239.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria,2M883@213115|Desulfovibrionales	28221|Deltaproteobacteria	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
YHH1_k127_1870741_7	335543.Sfum_4011	8.498e-22	99.0	COG0375@1|root,COG0375@2|Bacteria,1PTY9@1224|Proteobacteria,43EVX@68525|delta/epsilon subdivisions,2X23R@28221|Deltaproteobacteria,2MQPJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
YHH1_k127_1870741_4	1449063.JMLS01000003_gene1836	5.355e-44	168.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,26V63@186822|Paenibacillaceae	91061|Bacilli	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
YHH1_k127_1887445_2	1089552.KI911559_gene415	4.567e-05	47.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,2JQ3U@204441|Rhodospirillales	204441|Rhodospirillales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH1_k127_1887445_0	340177.Cag_1551	2.073e-27	116.0	COG0724@1|root,COG0724@2|Bacteria,1FE64@1090|Chlorobi	1090|Chlorobi	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_1899162_10	304371.MCP_1300	1.81e-11	67.0	COG1131@1|root,arCOG00194@2157|Archaea,2XVFB@28890|Euryarchaeota,2NARP@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH1_k127_1899162_4	1196323.ALKF01000149_gene1456	1.438e-97	338.0	COG1277@1|root,COG1277@2|Bacteria,1UP3Z@1239|Firmicutes,4IUZZ@91061|Bacilli,276YX@186822|Paenibacillaceae	2|Bacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1899162_2	316067.Geob_2357	1.497e-125	413.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,42NT4@68525|delta/epsilon subdivisions,2WJFM@28221|Deltaproteobacteria,43T76@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_1899162_1	1379698.RBG1_1C00001G1667	5.632e-126	413.0	COG0577@1|root,COG0577@2|Bacteria,2NQPT@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_1899162_5	1379698.RBG1_1C00001G1666	3.408e-96	319.0	COG1136@1|root,COG1136@2|Bacteria,2NPA8@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_1899162_3	1379698.RBG1_1C00001G1665	4.211e-110	369.0	COG0845@1|root,COG0845@2|Bacteria,2NQ2U@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	acrA	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH1_k127_1899162_8	869210.Marky_0827	1.516e-25	108.0	COG2151@1|root,COG2151@2|Bacteria,1WK4T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG2151 metal-sulfur cluster biosynthetic protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
YHH1_k127_1899162_7	1382304.JNIL01000001_gene3220	5.935e-37	145.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,279WU@186823|Alicyclobacillaceae	91061|Bacilli	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YHH1_k127_1899162_0	935845.JADQ01000012_gene2762	4.51e-144	468.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,26RKR@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YHH1_k127_1899162_9	926550.CLDAP_20390	1.534e-19	94.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
YHH1_k127_1899162_6	314230.DSM3645_24777	7.014e-63	228.0	COG0719@1|root,COG0719@2|Bacteria,2IY25@203682|Planctomycetes	203682|Planctomycetes	O	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
YHH1_k127_1908545_0	1340493.JNIF01000003_gene2186	9.065e-184	610.0	COG1026@1|root,COG1026@2|Bacteria	2|Bacteria	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
YHH1_k127_1926300_1	435908.IDSA_03625	1.702e-34	136.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,2QFQ8@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
YHH1_k127_1926300_0	573061.Clocel_3666	1.128e-96	327.0	COG0535@1|root,COG0535@2|Bacteria,1TR85@1239|Firmicutes,249NQ@186801|Clostridia,36DDQ@31979|Clostridiaceae	186801|Clostridia	C	PFAM Radical SAM domain protein	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
YHH1_k127_1931515_0	1379698.RBG1_1C00001G1225	3.136e-85	292.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4,2.7.11.1	ko:K02945,ko:K03527,ko:K12132	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011	-	-	-	S1
YHH1_k127_1931515_3	1379698.RBG1_1C00001G1226	1.884e-43	166.0	COG0204@1|root,COG0204@2|Bacteria,2NPW3@2323|unclassified Bacteria	2|Bacteria	I	Phosphate acyltransferases	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH1_k127_1931515_2	1218173.BALCAV_0200475	3.276e-55	204.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,1ZBXZ@1386|Bacillus	91061|Bacilli	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
YHH1_k127_1931515_9	1218352.B597_001575	8.849e-11	63.0	COG3729@1|root,COG3729@2|Bacteria,1NH1J@1224|Proteobacteria,1TFZF@1236|Gammaproteobacteria,1Z3BE@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	general stress protein	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
YHH1_k127_1931515_6	1173028.ANKO01000078_gene3878	3.162e-21	98.0	COG3729@1|root,COG3729@2|Bacteria	2|Bacteria	D	General stress protein	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
YHH1_k127_1931515_7	1121943.KB900008_gene1982	3.531e-20	94.0	COG3729@1|root,COG3729@2|Bacteria,1N767@1224|Proteobacteria,1SCA5@1236|Gammaproteobacteria	1224|Proteobacteria	S	Stress-induced protein	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
YHH1_k127_1931515_8	1333856.L686_20420	2.488e-11	70.0	COG3729@1|root,COG3729@2|Bacteria,1NH1J@1224|Proteobacteria,1TFZF@1236|Gammaproteobacteria,1Z3BE@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	general stress protein	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
YHH1_k127_1931515_1	1121428.DESHY_50086___1	1.718e-59	216.0	COG0834@1|root,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,25C2V@186801|Clostridia,261MF@186807|Peptococcaceae	186801|Clostridia	ET	PFAM Bacterial extracellular solute-binding proteins, family 3	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
YHH1_k127_1931515_10	391596.PBAL39_23467	3.039e-10	71.0	2BHU5@1|root,32BXU@2|Bacteria,4P1KW@976|Bacteroidetes,1IURQ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1931515_5	1379698.RBG1_1C00001G0060	1.081e-24	108.0	COG1983@1|root,COG1983@2|Bacteria,2NQ85@2323|unclassified Bacteria	2|Bacteria	KT	PspC domain	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
YHH1_k127_1931515_4	1452718.JBOY01000190_gene845	9.708e-29	123.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_1942770_3	1120978.KB894085_gene5	8.183e-06	49.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,27G5D@186828|Carnobacteriaceae	91061|Bacilli	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
YHH1_k127_1942770_2	926569.ANT_04540	1.147e-42	158.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi	200795|Chloroflexi	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
YHH1_k127_1942770_0	221360.RS9917_05080	1.339e-130	430.0	COG0304@1|root,COG0304@2|Bacteria,1G1J5@1117|Cyanobacteria,1GZS9@1129|Synechococcus	1117|Cyanobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH1_k127_1942770_1	926569.ANT_22470	2.834e-71	243.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
YHH1_k127_199112_2	266117.Rxyl_1210	9.752e-100	336.0	COG0668@1|root,COG0668@2|Bacteria,2GZI1@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
YHH1_k127_199112_1	1047013.AQSP01000110_gene67	4.415e-118	389.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YHH1_k127_199112_0	368407.Memar_1426	7.139e-132	432.0	COG1055@1|root,arCOG00238@2157|Archaea,2XVDU@28890|Euryarchaeota,2N961@224756|Methanomicrobia	224756|Methanomicrobia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
YHH1_k127_199112_3	330214.NIDE2788	1.494e-17	89.0	2EBKA@1|root,335KQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1997256_2	290318.Cvib_0740	2.826e-41	157.0	COG1342@1|root,COG1342@2|Bacteria,1FF1T@1090|Chlorobi	1090|Chlorobi	S	Belongs to the UPF0251 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
YHH1_k127_1997256_7	234267.Acid_5765	1.493e-06	56.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
YHH1_k127_1997256_0	2340.JV46_27810	7.947e-69	241.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,1RRYS@1236|Gammaproteobacteria,1J6RV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
YHH1_k127_1997256_5	267608.RSc2346	4.931e-13	75.0	COG0500@1|root,COG2226@2|Bacteria,1RGJA@1224|Proteobacteria,2VTNT@28216|Betaproteobacteria,1K045@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
YHH1_k127_1997256_8	329726.AM1_3334	7.308e-06	50.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	sumf2	-	2.1.1.295	ko:K15257,ko:K18534	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07501,R10709,R10710	RC00003,RC01662	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
YHH1_k127_1997256_6	391603.FBALC1_13217	7.624e-08	63.0	28ZUV@1|root,2ZMJI@2|Bacteria,4P7QF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1997256_1	1408422.JHYF01000001_gene3007	5.324e-65	240.0	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,24B18@186801|Clostridia,36F5Q@31979|Clostridiaceae	186801|Clostridia	L	Flagellar Assembly Protein A	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA,Jag_N
YHH1_k127_1997256_3	1379698.RBG1_1C00001G0016	2.499e-26	112.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_1997256_4	525897.Dbac_1382	1.494e-14	79.0	COG0745@1|root,COG1639@1|root,COG4191@1|root,COG0745@2|Bacteria,COG1639@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria,2MAB3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein, response regulator receiver, histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD,HisKA,Response_reg
YHH1_k127_1997256_9	485913.Krac_7493	7.896e-05	53.0	COG2203@1|root,COG2508@1|root,COG3605@1|root,COG2203@2|Bacteria,COG2508@2|Bacteria,COG3605@2|Bacteria,2G67M@200795|Chloroflexi	2|Bacteria	T	PFAM GAF domain protein	-	-	4.1.2.17	ko:K01628,ko:K03406,ko:K21009	ko00051,ko01120,ko02020,ko02025,ko02030,map00051,map01120,map02020,map02025,map02030	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000,ko02035	-	-	-	GAF,GAF_2,HATPase_c,HTH_30,HisKA,MCPsignal,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YHH1_k127_2005812_1	1094980.Mpsy_1538	9.608e-24	118.0	COG2304@1|root,COG4934@1|root,arCOG02902@2157|Archaea,arCOG03665@2157|Archaea	2157|Archaea	O	tripeptidyl-peptidase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,Peptidase_S8,Pro-kuma_activ,VWA,VWA_2
YHH1_k127_2005812_2	1538295.JY96_16965	1.466e-15	91.0	COG2304@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
YHH1_k127_2005812_0	335543.Sfum_2372	4.95e-35	143.0	COG0535@1|root,COG0535@2|Bacteria,1MYFX@1224|Proteobacteria,42SB0@68525|delta/epsilon subdivisions,2WPF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH1_k127_2022346_0	880073.Calab_1657	3.46e-78	276.0	COG1408@1|root,COG1408@2|Bacteria,2NRFJ@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
YHH1_k127_2022346_1	452637.Oter_0776	1.256e-43	171.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2202@1|root,COG3829@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,46Z7I@74201|Verrucomicrobia	74201|Verrucomicrobia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,Response_reg
YHH1_k127_2026267_5	1408445.JHXP01000010_gene2222	2.632e-07	52.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RR8F@1236|Gammaproteobacteria,1JGM8@118969|Legionellales	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
YHH1_k127_2026267_2	1056820.KB900681_gene2859	5.844e-28	116.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH1_k127_2026267_4	261292.Nit79A3_2888	4.136e-22	98.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,2VMP0@28216|Betaproteobacteria,373NG@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH1_k127_2026267_0	1380394.JADL01000011_gene3905	6.595e-223	702.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2JPPV@204441|Rhodospirillales	204441|Rhodospirillales	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
YHH1_k127_2026267_1	204669.Acid345_1709	7.163e-31	134.0	COG0491@1|root,COG0491@2|Bacteria,3Y4D7@57723|Acidobacteria,2JKB5@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH1_k127_2026267_3	247633.GP2143_18126	4.045e-26	115.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_205206_1	429009.Adeg_1290	1.372e-38	147.0	COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,24N1H@186801|Clostridia,42H1D@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis	aroH	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
YHH1_k127_205206_0	706587.Desti_1323	1.361e-130	424.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,2MRCR@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM DAHP synthetase I	aroG-2	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
YHH1_k127_205206_2	477974.Daud_1182	1.508e-38	155.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,260K3@186807|Peptococcaceae	186801|Clostridia	E	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
YHH1_k127_205206_3	1121920.AUAU01000007_gene487	6.387e-38	148.0	COG0436@1|root,COG0436@2|Bacteria,3Y2IZ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH1_k127_2054020_2	379066.GAU_0803	2.342e-84	294.0	COG2091@1|root,COG2091@2|Bacteria,1ZUQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2054020_3	945713.IALB_2556	4.677e-64	240.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	mcp40H-4	-	-	ko:K02660,ko:K03406,ko:K07216,ko:K11525	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	4HB_MCP_1,GAF,HAMP,MCPsignal,dCache_1
YHH1_k127_2054020_4	1131812.JQMS01000001_gene805	1.237e-08	64.0	2BU2H@1|root,32PB8@2|Bacteria,4PABR@976|Bacteroidetes,1IDNF@117743|Flavobacteriia,2NYUG@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
YHH1_k127_2054020_0	269799.Gmet_2918	2.095e-304	972.0	COG0366@1|root,COG0366@2|Bacteria,1PDXT@1224|Proteobacteria,42MZ1@68525|delta/epsilon subdivisions,2WMHA@28221|Deltaproteobacteria,43U2K@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM alpha amylase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
YHH1_k127_2054020_1	761193.Runsl_1910	7.706e-196	631.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47N7Y@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
YHH1_k127_2066238_3	1198232.CYCME_0769	2.303e-25	105.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,4601G@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
YHH1_k127_2066238_1	1255043.TVNIR_2552	5.061e-67	229.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,1WYDZ@135613|Chromatiales	135613|Chromatiales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YHH1_k127_2066238_2	396588.Tgr7_2302	2.693e-53	189.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1WYHF@135613|Chromatiales	135613|Chromatiales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YHH1_k127_2066238_4	187272.Mlg_0479	1.036e-14	74.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria,1WZNA@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
YHH1_k127_2066238_0	396588.Tgr7_2304	1.557e-155	493.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1WWJA@135613|Chromatiales	135613|Chromatiales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YHH1_k127_2071801_2	1121428.DESHY_60196___1	1.098e-56	207.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,260YG@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,PDZ
YHH1_k127_2071801_0	537013.CLOSTMETH_02672	9.113e-131	430.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3WGNU@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
YHH1_k127_2071801_4	335543.Sfum_2453	5.722e-45	180.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1PFBF@1224|Proteobacteria,42RAR@68525|delta/epsilon subdivisions,2WN52@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Protein phosphatase 2C domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,SpoIIE
YHH1_k127_2071801_10	717605.Theco_1915	7.353e-08	62.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,4HGYN@91061|Bacilli,26WQ5@186822|Paenibacillaceae	91061|Bacilli	T	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	GO:0000003,GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
YHH1_k127_2071801_9	1469607.KK073769_gene5490	2.485e-12	71.0	COG1366@1|root,COG1366@2|Bacteria,1G5PW@1117|Cyanobacteria,1HN2Y@1161|Nostocales	1117|Cyanobacteria	T	TIGRFAM anti-anti-sigma factor	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YHH1_k127_2071801_3	1232410.KI421413_gene809	2.46e-50	201.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,43UH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
YHH1_k127_2071801_7	639282.DEFDS_1712	2.314e-27	116.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,2GETM@200930|Deferribacteres	200930|Deferribacteres	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
YHH1_k127_2071801_1	207559.Dde_1573	3.728e-85	293.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QJT@68525|delta/epsilon subdivisions,2WJ1S@28221|Deltaproteobacteria,2M8MF@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
YHH1_k127_2071801_6	1191523.MROS_2120	1.947e-31	127.0	COG0745@1|root,COG0745@2|Bacteria	1191523.MROS_2120|-	T	phosphorelay signal transduction system	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	-
YHH1_k127_2071801_5	118005.AWNK01000006_gene1183	1.333e-44	165.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
YHH1_k127_2071801_11	1379270.AUXF01000002_gene1691	5.327e-05	53.0	2F57Y@1|root,33XUE@2|Bacteria,1ZTSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2071801_8	944480.ATUV01000001_gene840	1.447e-22	99.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2M6JZ@213113|Desulfurellales	28221|Deltaproteobacteria	T	Histidine Phosphotransfer domain	cheA64H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
YHH1_k127_2084213_1	234267.Acid_3971	3.736e-107	354.0	COG1252@1|root,COG1252@2|Bacteria,3Y308@57723|Acidobacteria	57723|Acidobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YHH1_k127_2084213_6	1382304.JNIL01000001_gene446	1.771e-09	69.0	COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4HA43@91061|Bacilli,279C8@186823|Alicyclobacillaceae	91061|Bacilli	M	Glycosyl transferase 4-like	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_2084213_2	935863.AWZR01000003_gene2845	1.202e-54	207.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1X7Y9@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferases group 1	-	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
YHH1_k127_2084213_3	304371.MCP_2273	1.841e-50	195.0	arCOG00787@1|root,arCOG00787@2157|Archaea	2157|Archaea	L	UvrD REP helicase	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH1_k127_2084213_5	161156.JQKW01000006_gene1106	3.217e-36	154.0	COG1639@1|root,COG1639@2|Bacteria,2GGWZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
YHH1_k127_2084213_0	1047013.AQSP01000142_gene242	2.568e-252	794.0	COG2511@1|root,COG2511@2|Bacteria	2|Bacteria	J	GatB/GatE catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GatB_N
YHH1_k127_2084213_4	1321778.HMPREF1982_00036	2.454e-49	177.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,26881@186813|unclassified Clostridiales	186801|Clostridia	EJ	Psort location Cytoplasmic, score	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
YHH1_k127_2085684_2	926550.CLDAP_06530	7.665e-40	151.0	COG0006@1|root,COG0006@2|Bacteria,2G5J8@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
YHH1_k127_2085684_1	1123242.JH636434_gene5621	7.418e-44	165.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
YHH1_k127_2085684_3	439292.Bsel_0661	4.888e-19	91.0	2EEX1@1|root,338QB@2|Bacteria,1VGA4@1239|Firmicutes,4HPYN@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
YHH1_k127_2085684_0	316274.Haur_1430	3.819e-91	333.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
YHH1_k127_2127793_10	1304885.AUEY01000011_gene1761	1.138e-48	179.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2WINT@28221|Deltaproteobacteria,2MIZ6@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
YHH1_k127_2127793_8	335543.Sfum_0258	5.523e-51	190.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,42S19@68525|delta/epsilon subdivisions,2WNGU@28221|Deltaproteobacteria,2MRTR@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
YHH1_k127_2127793_6	1382304.JNIL01000001_gene1095	8.178e-93	318.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,278YX@186823|Alicyclobacillaceae	91061|Bacilli	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YHH1_k127_2127793_7	1379698.RBG1_1C00001G0220	3.13e-53	206.0	COG3292@1|root,COG3292@2|Bacteria,2NR5N@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	-	ko:K19693	-	-	-	-	ko00000,ko03000	-	-	-	HATPase_c,HTH_18,HisKA,Response_reg
YHH1_k127_2127793_17	204669.Acid345_0277	7.144e-11	73.0	COG4856@1|root,COG4856@2|Bacteria,3Y8QK@57723|Acidobacteria	57723|Acidobacteria	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
YHH1_k127_2127793_4	857293.CAAU_0570	2.647e-109	362.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,36DHM@31979|Clostridiaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YHH1_k127_2127793_3	1232410.KI421426_gene1341	1.252e-151	509.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,43RXX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
YHH1_k127_2127793_5	1379698.RBG1_1C00001G0941	2.812e-94	327.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2NP36@2323|unclassified Bacteria	2|Bacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
YHH1_k127_2127793_15	309807.SRU_2692	1.111e-14	83.0	COG2815@1|root,COG2815@2|Bacteria,4PEKM@976|Bacteroidetes,1FJ9K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PASTA	-	-	-	-	-	-	-	-	-	-	-	-	PASTA
YHH1_k127_2127793_18	1410612.JNKO01000002_gene2447	8.856e-11	70.0	COG1309@1|root,COG1309@2|Bacteria,1V1C8@1239|Firmicutes,24FZ9@186801|Clostridia,2PTWS@265975|Oribacterium	186801|Clostridia	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
YHH1_k127_2127793_2	1379698.RBG1_1C00001G1837	2.203e-192	606.0	COG1260@1|root,COG1260@2|Bacteria,2NNVE@2323|unclassified Bacteria	2|Bacteria	I	Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
YHH1_k127_2127793_11	1120972.AUMH01000013_gene2437	3.354e-47	178.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,278BR@186823|Alicyclobacillaceae	91061|Bacilli	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02535	Thymidylate_kin
YHH1_k127_2127793_9	1379698.RBG1_1C00001G1839	1.687e-49	196.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
YHH1_k127_2127793_14	278957.ABEA03000006_gene4188	1.028e-32	137.0	COG0730@1|root,COG0730@2|Bacteria,46V52@74201|Verrucomicrobia,3K9AP@414999|Opitutae	414999|Opitutae	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH1_k127_2127793_12	580327.Tthe_0264	6.963e-37	147.0	COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,24IHI@186801|Clostridia,42GA1@68295|Thermoanaerobacterales	186801|Clostridia	E	HAD-superfamily hydrolase, subfamily IB, PSPase-like	mtnX	-	-	-	-	-	-	-	-	-	-	-	HAD,Put_Phosphatase
YHH1_k127_2127793_0	1519464.HY22_12340	1.731e-231	743.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1FEI3@1090|Chlorobi	1090|Chlorobi	GJM	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
YHH1_k127_2127793_1	373903.Hore_08140	3.109e-200	633.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3WABP@53433|Halanaerobiales	186801|Clostridia	J	class II (D K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YHH1_k127_2127793_13	1125863.JAFN01000001_gene1366	2.571e-35	142.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42URE@68525|delta/epsilon subdivisions,2WR5V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_2127793_16	1267535.KB906767_gene3225	8.733e-12	70.0	COG5660@1|root,COG5660@2|Bacteria,3Y5KK@57723|Acidobacteria	57723|Acidobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
YHH1_k127_2159590_4	1121918.ARWE01000001_gene2193	6.516e-07	51.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,42RMP@68525|delta/epsilon subdivisions,2X5PZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
YHH1_k127_2159590_2	96561.Dole_2317	5.537e-17	81.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2159590_3	525897.Dbac_2186	2.081e-15	78.0	2DRFV@1|root,33BJD@2|Bacteria,1NM2T@1224|Proteobacteria,42WGX@68525|delta/epsilon subdivisions,2WR8G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2159590_0	379066.GAU_3859	1.229e-117	394.0	COG4784@1|root,COG4784@2|Bacteria,1ZUKG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH1_k127_2161658_3	1123288.SOV_5c01090	3.253e-67	233.0	COG1045@1|root,COG1045@2|Bacteria	2|Bacteria	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
YHH1_k127_2161658_1	1232666.JANE01000050_gene1929	5.355e-117	384.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,4GX3M@90964|Staphylococcaceae	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH1_k127_2161658_0	1379698.RBG1_1C00001G1403	4.535e-148	482.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
YHH1_k127_2161658_2	1379698.RBG1_1C00001G1403	8.412e-112	374.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
YHH1_k127_2164856_0	880073.Calab_3201	4.231e-144	467.0	COG4198@1|root,COG4198@2|Bacteria,2NNV0@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1015)	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	DUF1015
YHH1_k127_2164856_2	573413.Spirs_2138	6.387e-95	319.0	COG0111@1|root,COG0111@2|Bacteria,2JA4I@203691|Spirochaetes	203691|Spirochaetes	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH1_k127_2164856_1	1262914.BN533_00243	4.989e-136	442.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4H26T@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
YHH1_k127_2164856_3	682795.AciX8_0794	1.606e-15	83.0	COG1943@1|root,COG1943@2|Bacteria,3Y4PK@57723|Acidobacteria,2JJBM@204432|Acidobacteriia	204432|Acidobacteriia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH1_k127_2165613_0	870187.Thini_3879	3.11e-23	105.0	COG1879@1|root,COG2982@1|root,COG1879@2|Bacteria,COG2982@2|Bacteria,1QQQ2@1224|Proteobacteria,1RRG1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Peptidase M60-like family	-	-	-	ko:K21429	-	-	-	-	ko00000,ko01002	-	-	-	M60-like_N,Peptidase_M60
YHH1_k127_2166159_3	1157708.KB907459_gene2106	1.523e-110	362.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria,4AD46@80864|Comamonadaceae	28216|Betaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
YHH1_k127_2166159_1	95619.PM1_0202110	8.235e-189	599.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RMXA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fad linked oxidase	dprE1	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
YHH1_k127_2166159_4	95619.PM1_0202115	8.937e-96	322.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,1S25V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH1_k127_2166159_2	666681.M301_1239	3.061e-170	537.0	COG0702@1|root,COG0702@2|Bacteria,1PM6M@1224|Proteobacteria,2VMCW@28216|Betaproteobacteria	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YHH1_k127_2166159_0	666681.M301_1240	7.95e-191	599.0	COG1232@1|root,COG1232@2|Bacteria,1P80H@1224|Proteobacteria,2VNBE@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
YHH1_k127_2175539_2	1381123.AYOD01000067_gene199	4.115e-30	121.0	COG2329@1|root,COG2329@2|Bacteria,1RGVV@1224|Proteobacteria,2U9A3@28211|Alphaproteobacteria,43KD2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
YHH1_k127_2175539_3	1123053.AUDG01000040_gene1254	1.1e-09	59.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH1_k127_2175539_0	435908.IDSA_09295	1.487e-79	274.0	COG3713@1|root,COG3713@2|Bacteria,1QSEK@1224|Proteobacteria,1RNGI@1236|Gammaproteobacteria,2QGPK@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	MltA-interacting protein MipA	-	-	-	-	-	-	-	-	-	-	-	-	MipA
YHH1_k127_2175539_1	566466.NOR53_3391	3.523e-44	171.0	COG3279@1|root,COG3279@2|Bacteria,1N903@1224|Proteobacteria,1S6QI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
YHH1_k127_2175539_4	1243664.CAVL020000061_gene3853	7.295e-09	58.0	29S0J@1|root,30D4W@2|Bacteria,1UAUR@1239|Firmicutes,4IM7J@91061|Bacilli,1ZJEQ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2175792_1	1144275.COCOR_05233	6.614e-29	125.0	COG2849@1|root,COG2849@2|Bacteria,1NMUU@1224|Proteobacteria,432BU@68525|delta/epsilon subdivisions,2WT7D@28221|Deltaproteobacteria,2Z2M9@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
YHH1_k127_2175792_2	1230343.CANP01000031_gene2423	1.888e-13	71.0	COG5487@1|root,COG5487@2|Bacteria	2|Bacteria	S	UPF0391 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
YHH1_k127_2175792_0	269799.Gmet_0754	3.494e-103	349.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,43UZT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,DZR,SHOCT,zinc_ribbon_2
YHH1_k127_2175792_3	984262.SGRA_2874	0.0001488	53.0	COG1594@1|root,COG1594@2|Bacteria,4PKAQ@976|Bacteroidetes,1IWYV@117747|Sphingobacteriia	976|Bacteroidetes	K	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2177275_0	1219084.AP014508_gene1794	3.631e-99	334.0	COG0330@1|root,COG0330@2|Bacteria,2GC8F@200918|Thermotogae	200918|Thermotogae	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH1_k127_2177275_1	190650.CC_3374	5.089e-09	63.0	COG1585@1|root,COG1585@2|Bacteria,1PVR4@1224|Proteobacteria,2UEDQ@28211|Alphaproteobacteria,2KGY1@204458|Caulobacterales	204458|Caulobacterales	OU	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
YHH1_k127_2184334_1	1408312.JNJS01000006_gene771	6.166e-83	289.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,24A6D@186801|Clostridia	186801|Clostridia	C	Radical SAM domain protein	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
YHH1_k127_2184334_3	203119.Cthe_0533	9.58e-75	265.0	COG0457@1|root,COG0535@1|root,COG0457@2|Bacteria,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WHA6@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH1_k127_2184334_0	1128421.JAGA01000003_gene2772	7.916e-115	392.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	msbA2	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH1_k127_2184334_5	351160.RCIX1056	1.301e-13	81.0	arCOG03443@1|root,arCOG03443@2157|Archaea,2Y0YU@28890|Euryarchaeota	28890|Euryarchaeota	S	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RLAN
YHH1_k127_2184334_2	1449126.JQKL01000009_gene370	8.858e-75	261.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	rimK	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Dala_Dala_lig_C,RLAN,RimK
YHH1_k127_2184334_4	926569.ANT_06160	1.762e-25	116.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YHH1_k127_2234878_2	164328.Phyra75333	1.951e-14	83.0	KOG1947@1|root,KOG1947@2759|Eukaryota,3QCMI@4776|Peronosporales	4776|Peronosporales	S	Leucine-rich repeat - CC (cysteine-containing) subfamily	-	-	-	ko:K10279,ko:K10280	-	-	-	-	ko00000,ko04121	-	-	-	LRR_6
YHH1_k127_2234878_1	416348.Hlac_3636	6.963e-33	133.0	COG3415@1|root,arCOG02128@2157|Archaea	2157|Archaea	L	COG3415 Transposase and inactivated derivatives	-	-	-	ko:K07499	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32,HTH_33
YHH1_k127_2234878_0	1123508.JH636456_gene119	3.873e-33	134.0	COG3335@1|root,COG3335@2|Bacteria,2J1BU@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
YHH1_k127_2234878_3	1221522.B723_08385	1.214e-07	55.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1YTCG@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis protein C-terminal	fnlA	-	5.1.3.2	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00362	R00291	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
YHH1_k127_2261606_0	1379698.RBG1_1C00001G1194	2.083e-55	222.0	COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	3.2.1.91	ko:K14194,ko:K19668	ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CHU_C,DUF11,FlgD_ig,PKD,SdrD_B
YHH1_k127_2261606_1	215803.DB30_4240	1.108e-08	68.0	COG3055@1|root,COG3055@2|Bacteria,1QX72@1224|Proteobacteria,43BZV@68525|delta/epsilon subdivisions,2X7AM@28221|Deltaproteobacteria,2YX4N@29|Myxococcales	28221|Deltaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2261742_4	1198449.ACAM_0491	3.298e-36	143.0	COG0124@1|root,arCOG00404@2157|Archaea,2XPY6@28889|Crenarchaeota	28889|Crenarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YHH1_k127_2261742_5	649831.L083_2223	3.011e-21	99.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.144,2.1.1.197	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_19,Methyltransf_23,Methyltransf_25
YHH1_k127_2261742_1	945713.IALB_1148	1.687e-236	737.0	COG2079@1|root,COG2079@2|Bacteria	2|Bacteria	S	2-methylcitrate dehydratase activity	prpD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
YHH1_k127_2261742_0	880073.Calab_1833	2.683e-312	968.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,2NNYT@2323|unclassified Bacteria	2|Bacteria	E	Aconitase family (aconitate hydratase)	leuD	-	4.2.1.33,4.2.1.35,4.2.1.36	ko:K01703,ko:K01704,ko:K01705	ko00290,ko00300,ko00660,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00966,map01100,map01110,map01120,map01130,map01210,map01230	M00030,M00432,M00433,M00535	R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH1_k127_2261742_3	1047013.AQSP01000140_gene2449	2.907e-43	164.0	COG1418@1|root,COG1418@2|Bacteria,2NPXI@2323|unclassified Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950,ko:K09163	-	-	-	-	ko00000	-	-	-	HD
YHH1_k127_2261742_2	398767.Glov_1510	9.756e-143	460.0	COG0673@1|root,COG0673@2|Bacteria,1PXE1@1224|Proteobacteria,42MSE@68525|delta/epsilon subdivisions,2WKIS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH1_k127_2266895_0	1125863.JAFN01000001_gene336	4.417e-124	417.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RF9@68525|delta/epsilon subdivisions,2WNQF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YHH1_k127_2266895_1	1121930.AQXG01000001_gene1216	4.622e-26	109.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Beta_helix,F5_F8_type_C
YHH1_k127_2272396_1	880073.Calab_0781	2e-38	151.0	COG1595@1|root,COG1595@2|Bacteria,2NR5T@2323|unclassified Bacteria	2|Bacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	sigG	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_2272396_4	661478.OP10G_1575	0.0001151	52.0	2EGRR@1|root,33AHX@2|Bacteria	2|Bacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
YHH1_k127_2272396_3	1177179.A11A3_02057	1.135e-22	111.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XICI@135619|Oceanospirillales	135619|Oceanospirillales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04691,ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
YHH1_k127_2272396_2	379066.GAU_1903	5.982e-24	111.0	COG0599@1|root,COG0599@2|Bacteria,1ZTPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
YHH1_k127_2272396_0	1379698.RBG1_1C00001G1524	1.278e-59	231.0	COG2911@1|root,COG2911@2|Bacteria,2NQ89@2323|unclassified Bacteria	2|Bacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K07277,ko:K09800	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	AsmA_2,DUF748,TamB
YHH1_k127_2303453_2	382245.ASA_0097	3.532e-22	109.0	COG3306@1|root,COG3306@2|Bacteria,1N6W4@1224|Proteobacteria,1SFH1@1236|Gammaproteobacteria,1Y6CR@135624|Aeromonadales	135624|Aeromonadales	M	Glycosyltransferase family 25 (LPS biosynthesis protein)	-	-	-	ko:K07270	-	-	-	-	ko00000	-	GT25	-	Glyco_transf_25
YHH1_k127_2303453_1	351348.Maqu_1651	1.08e-55	209.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,1RSI9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
YHH1_k127_2303453_0	203122.Sde_0145	2.273e-90	307.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,465HY@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	pslH	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
YHH1_k127_2305050_7	385682.AFSL01000064_gene1710	5.551e-20	95.0	COG4109@1|root,COG4109@2|Bacteria,4NTA0@976|Bacteroidetes,2FTZ6@200643|Bacteroidia,3XKAD@558415|Marinilabiliaceae	976|Bacteroidetes	K	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
YHH1_k127_2305050_4	1209989.TepiRe1_2041	3.423e-53	198.0	COG2172@1|root,COG2172@2|Bacteria,1V6YP@1239|Firmicutes,24JJ0@186801|Clostridia,42GXK@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	RsbW	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2
YHH1_k127_2305050_3	1209989.TepiRe1_2040	5.546e-92	317.0	COG2000@1|root,COG2221@1|root,COG4624@1|root,COG2000@2|Bacteria,COG2221@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,24BF5@186801|Clostridia,42F1E@68295|Thermoanaerobacterales	186801|Clostridia	C	Fe-S cluster domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,Fer4_9
YHH1_k127_2305050_6	909663.KI867150_gene401	1.345e-39	153.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,42U8S@68525|delta/epsilon subdivisions,2WQ8V@28221|Deltaproteobacteria,2MQIE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE-1	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YHH1_k127_2305050_0	264732.Moth_1718	2.699e-211	673.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,42EM7@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding	nuoF2	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
YHH1_k127_2305050_1	909663.KI867150_gene399	2.05e-160	536.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MR16@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase, Fe4S4	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
YHH1_k127_2305050_2	909663.KI867150_gene398	2.204e-104	346.0	COG0543@1|root,COG0543@2|Bacteria,1NTWI@1224|Proteobacteria,42M66@68525|delta/epsilon subdivisions,2WJJ2@28221|Deltaproteobacteria,2MRSB@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	nfnB	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
YHH1_k127_2305050_5	909663.KI867150_gene397	2.315e-42	157.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MREN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
YHH1_k127_2345072_0	1379698.RBG1_1C00001G0715	1.523e-116	387.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH1_k127_2345072_2	867903.ThesuDRAFT_01499	1.767e-23	108.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YHH1_k127_2364618_0	1282362.AEAC466_02235	7.893e-81	278.0	COG3410@1|root,COG3410@2|Bacteria,1PRQ3@1224|Proteobacteria,2U2KB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
YHH1_k127_2364618_2	1232410.KI421413_gene852	3.884e-35	143.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	pcaC	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
YHH1_k127_2364618_4	1379698.RBG1_1C00001G0198	6.302e-12	78.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YHH1_k127_2364618_1	1123368.AUIS01000004_gene214	3.591e-67	238.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YHH1_k127_2366521_0	518766.Rmar_0629	1.522e-235	763.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
YHH1_k127_2379132_2	477974.Daud_1544	6.269e-86	294.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,25ZY7@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
YHH1_k127_2379132_1	358396.C445_17761	5.683e-98	335.0	COG2311@1|root,arCOG06418@2157|Archaea,2XUST@28890|Euryarchaeota,23U4C@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
YHH1_k127_2379132_5	679926.Mpet_1806	6.694e-11	74.0	COG0840@1|root,COG2770@1|root,arCOG02366@1|root,arCOG02320@2157|Archaea,arCOG02366@2157|Archaea,arCOG02372@2157|Archaea,2XTG0@28890|Euryarchaeota	28890|Euryarchaeota	N	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,PAS_4,dCache_1,sCache_3_3
YHH1_k127_2379132_4	56780.SYN_00776	4.957e-42	168.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,1NWNJ@1224|Proteobacteria,42QTD@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HATPase_c,HTH_3,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,SBP_bac_3
YHH1_k127_2379132_3	909663.KI867151_gene3160	1.326e-66	234.0	COG2197@1|root,COG2197@2|Bacteria,1RARA@1224|Proteobacteria,43B1G@68525|delta/epsilon subdivisions,2X5U5@28221|Deltaproteobacteria,2MRK4@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_2379132_0	1408473.JHXO01000005_gene1601	3.235e-173	554.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,2FNEC@200643|Bacteroidia	976|Bacteroidetes	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
YHH1_k127_2383109_1	1379698.RBG1_1C00001G1804	6.624e-48	177.0	2E8AI@1|root,332PD@2|Bacteria,2NRHQ@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2383109_3	1379698.RBG1_1C00001G1805	5.456e-14	74.0	COG1826@1|root,COG1826@2|Bacteria,2NQ3N@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
YHH1_k127_2383109_0	518766.Rmar_2306	4.062e-96	319.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1FIWZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
YHH1_k127_2383109_4	1231377.C426_1547	3.08e-07	53.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,1YCH4@1357|Lactococcus	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
YHH1_k127_2415144_0	1266909.AUAG01000063_gene1806	2.961e-152	489.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,1WZPM@135613|Chromatiales	135613|Chromatiales	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH1_k127_2419245_3	1162668.LFE_1804	1.592e-80	275.0	COG0372@1|root,COG0372@2|Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1,4.1.3.34	ko:K01647,ko:K15234	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R00351,R00354	RC00004,RC00067,RC00502	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
YHH1_k127_2419245_5	1121396.KB893071_gene1265	1.478e-54	200.0	COG0489@1|root,COG0489@2|Bacteria,1R6AC@1224|Proteobacteria,42NTJ@68525|delta/epsilon subdivisions,2WM95@28221|Deltaproteobacteria,2MJ5Z@213118|Desulfobacterales	28221|Deltaproteobacteria	D	protein tyrosine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2419245_9	521045.Kole_2161	7.824e-19	88.0	COG1146@1|root,COG1146@2|Bacteria,2GDEK@200918|Thermotogae	200918|Thermotogae	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
YHH1_k127_2419245_1	1121405.dsmv_1449	1.951e-145	470.0	COG0674@1|root,COG0674@2|Bacteria,1MWCI@1224|Proteobacteria,42NJY@68525|delta/epsilon subdivisions,2WIW3@28221|Deltaproteobacteria,2MHPN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorA	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1307	PFOR_II,POR_N
YHH1_k127_2419245_2	177437.HRM2_10700	1.461e-116	379.0	COG1013@1|root,COG1013@2|Bacteria,1N0HY@1224|Proteobacteria,42MTM@68525|delta/epsilon subdivisions,2WJS6@28221|Deltaproteobacteria,2MIRW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
YHH1_k127_2419245_4	1265505.ATUG01000001_gene4025	7.712e-55	198.0	COG1014@1|root,COG1014@2|Bacteria,1R92Y@1224|Proteobacteria,42QJI@68525|delta/epsilon subdivisions,2WMFZ@28221|Deltaproteobacteria,2MJ4M@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
YHH1_k127_2419245_7	880072.Desac_1352	2.475e-42	160.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,42U8S@68525|delta/epsilon subdivisions,2WQ8V@28221|Deltaproteobacteria,2MQIE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE-1	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YHH1_k127_2419245_0	255470.cbdbA684	1.847e-237	749.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi,34D48@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
YHH1_k127_2419245_6	255470.cbdbA685	2.461e-48	182.0	COG3383@1|root,COG3383@2|Bacteria,2GAS8@200795|Chloroflexi,34D7W@301297|Dehalococcoidia	301297|Dehalococcoidia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4
YHH1_k127_2419245_8	1089553.Tph_c04170	7.177e-37	144.0	COG1142@1|root,COG1142@2|Bacteria,1UHYS@1239|Firmicutes,24JZC@186801|Clostridia,42H3B@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_3,Fer4_4,Fer4_6,Fer4_9
YHH1_k127_2448920_0	357808.RoseRS_1569	4.785e-65	234.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin,Trypsin_2
YHH1_k127_2448920_2	208444.JNYY01000008_gene8612	0.0006689	46.0	COG0265@1|root,COG0265@2|Bacteria,2ICC4@201174|Actinobacteria,4E1VC@85010|Pseudonocardiales	201174|Actinobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2485218_0	1379698.RBG1_1C00001G1471	2.233e-270	838.0	COG4799@1|root,COG4799@2|Bacteria,2NNWQ@2323|unclassified Bacteria	2|Bacteria	I	carboxyl transferase	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YHH1_k127_2485218_12	1379698.RBG1_1C00001G1472	2.226e-72	254.0	COG0491@1|root,COG0491@2|Bacteria,2NPRD@2323|unclassified Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH1_k127_2485218_6	1379698.RBG1_1C00001G1473	7.324e-138	449.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha
YHH1_k127_2485218_14	1379698.RBG1_1C00001G1474	1.197e-56	200.0	COG2185@1|root,COG2185@2|Bacteria,2NPGA@2323|unclassified Bacteria	2|Bacteria	I	Cobalamin B12-binding	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
YHH1_k127_2485218_1	1379698.RBG1_1C00001G1475	3.623e-236	743.0	COG1884@1|root,COG1884@2|Bacteria,2NNZ9@2323|unclassified Bacteria	2|Bacteria	I	Methylmalonyl-CoA mutase	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
YHH1_k127_2485218_23	143224.JQMD01000002_gene560	3.191e-12	79.0	2EVZZ@1|root,33PDF@2|Bacteria,4P17P@976|Bacteroidetes,1I798@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2485218_22	143224.JQMD01000002_gene560	7.158e-13	80.0	2EVZZ@1|root,33PDF@2|Bacteria,4P17P@976|Bacteroidetes,1I798@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2485218_11	1379698.RBG1_1C00001G1476	8.981e-78	271.0	COG1703@1|root,COG1703@2|Bacteria,2NP56@2323|unclassified Bacteria	2|Bacteria	E	LAO AO transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
YHH1_k127_2485218_5	1379698.RBG1_1C00001G1477	1.647e-177	577.0	COG0608@1|root,COG0608@2|Bacteria,2NNRX@2323|unclassified Bacteria	2|Bacteria	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH1_k127_2485218_24	34506.g3068	3.569e-05	48.0	2D1ZE@1|root,2SJVP@2759|Eukaryota,3AI9D@33154|Opisthokonta,3BX0X@33208|Metazoa,3DEMU@33213|Bilateria	33208|Metazoa	S	LppC putative lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LppC
YHH1_k127_2485218_3	224324.aq_2023	1.968e-181	580.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G3I9@200783|Aquificae	200783|Aquificae	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
YHH1_k127_2485218_15	1379698.RBG1_1C00001G1480	4.171e-56	205.0	COG1579@1|root,COG1579@2|Bacteria,2NPW0@2323|unclassified Bacteria	2|Bacteria	S	C4-type zinc ribbon domain	CP_0228	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
YHH1_k127_2485218_9	1220534.B655_1784	2.964e-82	293.0	COG0065@1|root,arCOG01698@2157|Archaea,2XTWH@28890|Euryarchaeota,23PD9@183925|Methanobacteria	183925|Methanobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
YHH1_k127_2485218_16	944480.ATUV01000002_gene120	3.761e-53	193.0	COG0537@1|root,COG0537@2|Bacteria,1RHYQ@1224|Proteobacteria,42SEG@68525|delta/epsilon subdivisions,2WPFW@28221|Deltaproteobacteria,2M6KA@213113|Desulfurellales	28221|Deltaproteobacteria	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	CwfJ_C_1,HIT
YHH1_k127_2485218_10	457570.Nther_2188	5.213e-81	295.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
YHH1_k127_2485218_7	1379698.RBG1_1C00001G0178	6.676e-117	391.0	COG2265@1|root,COG2265@2|Bacteria,2NNWX@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
YHH1_k127_2485218_13	521045.Kole_0424	8.539e-62	226.0	COG1230@1|root,COG1230@2|Bacteria,2GCWV@200918|Thermotogae	200918|Thermotogae	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
YHH1_k127_2485218_4	1189612.A33Q_3068	4.571e-178	571.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YHH1_k127_2485218_20	1313301.AUGC01000012_gene1345	1.469e-19	96.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes	976|Bacteroidetes	I	Biotin carboxyl carrier protein	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
YHH1_k127_2485218_2	273068.TTE2389	1.32e-217	686.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
YHH1_k127_2485218_17	529709.PYCH_16970	7.116e-38	147.0	COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,24458@183968|Thermococci	183968|Thermococci	E	Glyoxalase-like domain	-	GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
YHH1_k127_2485218_21	357808.RoseRS_0532	2.651e-15	84.0	COG3682@1|root,COG3682@2|Bacteria,2GAQU@200795|Chloroflexi,37733@32061|Chloroflexia	32061|Chloroflexia	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YHH1_k127_2485218_25	1538644.KO02_19125	3.744e-05	48.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
YHH1_k127_2485218_18	1268237.G114_18546	1.906e-25	110.0	2E5AU@1|root,3302Y@2|Bacteria,1RFJF@1224|Proteobacteria,1S5HE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Src homology 3 domains	-	-	-	-	-	-	-	-	-	-	-	-	SH3_2
YHH1_k127_2485218_19	933262.AXAM01000039_gene1166	5.575e-24	110.0	COG1102@1|root,COG1102@2|Bacteria,1RCTZ@1224|Proteobacteria,42R0B@68525|delta/epsilon subdivisions,2WMVD@28221|Deltaproteobacteria,2MJH5@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
YHH1_k127_2485218_8	945713.IALB_1809	7.795e-108	357.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571,ko:K03497	-	-	-	-	ko00000,ko01000,ko02048,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc,RE_Eco29kI
YHH1_k127_2520321_1	309799.DICTH_0276	5.733e-36	138.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016020,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0071944,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	iPC815.YPO3064	AhpC-TSA
YHH1_k127_2520321_0	671143.DAMO_2354	9.805e-93	314.0	COG1090@1|root,COG1090@2|Bacteria,2NPHC@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
YHH1_k127_2520321_2	314230.DSM3645_21362	4.346e-07	54.0	2BRMF@1|root,32KKV@2|Bacteria,2J49V@203682|Planctomycetes	203682|Planctomycetes	S	Winged helix-turn-helix domain (DUF2582)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2582
YHH1_k127_2566092_0	1120953.AUBH01000002_gene1510	3.843e-115	383.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1S0CZ@1236|Gammaproteobacteria,46A8H@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Penicillin amidase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
YHH1_k127_2566092_1	398767.Glov_1719	3.751e-66	239.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,42NZH@68525|delta/epsilon subdivisions,2WKHB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_C7,Cytochrome_cB
YHH1_k127_2568538_8	1550091.JROE01000004_gene1292	3.357e-63	220.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1INWD@117747|Sphingobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH1_k127_2568538_2	929556.Solca_2810	3.921e-111	368.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1INPZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
YHH1_k127_2568538_12	981383.AEWH01000068_gene297	1.395e-18	94.0	COG1587@1|root,COG1587@2|Bacteria,1UHSJ@1239|Firmicutes,4HFY4@91061|Bacilli	91061|Bacilli	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
YHH1_k127_2568538_6	1122176.KB903535_gene1980	1.802e-74	260.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1IQUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
YHH1_k127_2568538_10	338963.Pcar_3064	1.108e-46	185.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
YHH1_k127_2568538_0	349741.Amuc_1222	1.091e-203	655.0	COG1297@1|root,COG1297@2|Bacteria,46TNW@74201|Verrucomicrobia,2IV9P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
YHH1_k127_2568538_3	368407.Memar_1357	6.665e-104	347.0	COG0265@1|root,arCOG02833@2157|Archaea,2XT7Y@28890|Euryarchaeota,2NAWS@224756|Methanomicrobia	224756|Methanomicrobia	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YHH1_k127_2568538_11	1134912.AJTV01000055_gene3845	9.82e-46	173.0	COG3000@1|root,COG3000@2|Bacteria,1RA8D@1224|Proteobacteria,2U5A3@28211|Alphaproteobacteria,36ZUE@31993|Methylocystaceae	28211|Alphaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
YHH1_k127_2568538_4	251229.Chro_1450	1.124e-101	342.0	COG0346@1|root,COG0400@1|root,COG0346@2|Bacteria,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999,ko:K15975	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Glyoxalase
YHH1_k127_2568538_7	1166018.FAES_0457	1.992e-68	239.0	COG0400@1|root,COG0400@2|Bacteria,4NF4I@976|Bacteroidetes,47PPZ@768503|Cytophagia	976|Bacteroidetes	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
YHH1_k127_2568538_14	1279019.ARQK01000061_gene1826	8.969e-05	51.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,1WY90@135613|Chromatiales	135613|Chromatiales	N	Required for flagellar hook formation. May act as a scaffolding protein	-	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
YHH1_k127_2568538_1	358681.BBR47_43950	1.263e-114	386.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli,275KV@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
YHH1_k127_2568538_13	1123059.KB823011_gene1697	7.996e-07	59.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,2TSMV@28211|Alphaproteobacteria,43WIZ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	KQ	transcriptional	arsR	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Methyltransf_11,Methyltransf_31
YHH1_k127_2568538_5	1408473.JHXO01000011_gene3210	3.849e-86	296.0	COG0421@1|root,COG0421@2|Bacteria,4NTHI@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_257606_1	1379698.RBG1_1C00001G1884	5.346e-49	181.0	COG0558@1|root,COG0558@2|Bacteria,2NPJ9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06365	CDP-OH_P_transf
YHH1_k127_257606_2	1519464.HY22_12230	4.792e-29	123.0	COG1267@1|root,COG1267@2|Bacteria,1FE6P@1090|Chlorobi	1090|Chlorobi	I	PFAM phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
YHH1_k127_257606_0	1379698.RBG1_1C00001G1886	1.121e-56	204.0	COG1058@1|root,COG1058@2|Bacteria,2NP0G@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
YHH1_k127_2576517_3	861299.J421_3248	5.602e-27	121.0	COG0438@1|root,COG0438@2|Bacteria,1ZSTJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_2576517_2	694427.Palpr_0129	1.094e-69	249.0	COG1562@1|root,COG1562@2|Bacteria	2|Bacteria	I	ergosterol biosynthetic process	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
YHH1_k127_2576517_0	1379698.RBG1_1C00001G0415	1.569e-110	372.0	COG5316@1|root,COG5316@2|Bacteria,2NPBR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
YHH1_k127_2576517_4	929556.Solca_4246	1.379e-13	83.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
YHH1_k127_2576517_1	518766.Rmar_2052	3.01e-99	344.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1FJ34@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
YHH1_k127_2584294_3	445971.ANASTE_01039	3.408e-08	57.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,25UWN@186806|Eubacteriaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
YHH1_k127_2584294_4	1121472.AQWN01000003_gene1545	0.000307	45.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24WDA@186801|Clostridia,2664T@186807|Peptococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH1_k127_2584294_0	1329516.JPST01000011_gene368	7.075e-40	158.0	COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,27CQQ@186824|Thermoactinomycetaceae	91061|Bacilli	S	D5 N terminal like	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,PriCT_1,Prim-Pol
YHH1_k127_2584294_1	370438.PTH_1394	1.412e-11	66.0	COG1414@1|root,COG3598@1|root,COG1414@2|Bacteria,COG3598@2|Bacteria,1TU5N@1239|Firmicutes,247KK@186801|Clostridia,265S3@186807|Peptococcaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
YHH1_k127_2617516_1	880073.Calab_1608	1.083e-93	316.0	COG0437@1|root,COG0437@2|Bacteria,2NPJ0@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7
YHH1_k127_2617516_0	1191523.MROS_1571	8.618e-137	447.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	hybB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	iAPECO1_1312.APECO1_3427,iE2348C_1286.E2348C_3282,iECABU_c1320.ECABU_c34010,iECOK1_1307.ECOK1_3414,iECS88_1305.ECS88_3377,iUMN146_1321.UM146_01380,iUTI89_1310.UTI89_C3417	NrfD
YHH1_k127_2617516_2	1379698.RBG1_1C00001G0775	2.929e-61	225.0	COG0484@1|root,COG0484@2|Bacteria,2NQUM@2323|unclassified Bacteria	2|Bacteria	O	Class III cytochrome C family	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2
YHH1_k127_2629314_3	426114.THI_2293	0.000111	51.0	2D8TI@1|root,32TRX@2|Bacteria,1N5N2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2629314_2	1047013.AQSP01000100_gene581	5.995e-25	109.0	COG1895@1|root,COG1895@2|Bacteria	2|Bacteria	O	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
YHH1_k127_2629314_1	1120999.JONM01000021_gene103	8.044e-26	113.0	COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,2VQYD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,NTP_transf_2
YHH1_k127_2629314_0	43759.JNWK01000032_gene4231	1.369e-36	142.0	COG2154@1|root,COG2154@2|Bacteria,2IHZE@201174|Actinobacteria	201174|Actinobacteria	H	dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YHH1_k127_2647620_4	216595.PFLU_3292	2.279e-26	122.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
YHH1_k127_2647620_0	1379698.RBG1_1C00001G0529	7.082e-98	332.0	COG0520@1|root,COG0520@2|Bacteria,2NP4B@2323|unclassified Bacteria	2|Bacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YHH1_k127_2647620_1	1254432.SCE1572_42010	1.052e-64	233.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42TZR@68525|delta/epsilon subdivisions,2WQAW@28221|Deltaproteobacteria,2YV9A@29|Myxococcales	28221|Deltaproteobacteria	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH1_k127_2647620_6	745411.B3C1_04510	2.342e-15	79.0	COG5033@1|root,COG5033@2|Bacteria,1NBJM@1224|Proteobacteria,1SGE8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	YEATS family	-	-	-	-	-	-	-	-	-	-	-	-	YEATS
YHH1_k127_2647620_8	91464.S7335_4448	3.201e-09	64.0	COG3126@1|root,COG3187@1|root,COG3126@2|Bacteria,COG3187@2|Bacteria,1G7AX@1117|Cyanobacteria	1117|Cyanobacteria	O	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	-	-	-	-	-	-	-	-	-	YscW
YHH1_k127_2647620_7	1170562.Cal6303_4322	5.059e-10	63.0	2DNT7@1|root,32Z0Z@2|Bacteria,1G93V@1117|Cyanobacteria	1117|Cyanobacteria	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
YHH1_k127_2647620_2	1303518.CCALI_01893	5.089e-39	163.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH1_k127_2647620_5	1121106.JQKB01000059_gene4749	1.012e-21	106.0	COG0454@1|root,COG0456@2|Bacteria,1R418@1224|Proteobacteria,2U1QH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH1_k127_2647620_9	525904.Tter_0247	1.07e-08	62.0	COG3794@1|root,COG3794@2|Bacteria,2NRPQ@2323|unclassified Bacteria	2|Bacteria	C	blue (type 1) copper	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
YHH1_k127_2647620_3	1379698.RBG1_1C00001G0182	6.63e-33	133.0	COG0340@1|root,COG0340@2|Bacteria,2NPG2@2323|unclassified Bacteria	2|Bacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
YHH1_k127_2679280_5	246197.MXAN_3068	1.547e-13	70.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2YX6I@29|Myxococcales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH1_k127_2679280_3	1379698.RBG1_1C00001G1598	3.436e-44	164.0	COG0051@1|root,COG0051@2|Bacteria,2NPJY@2323|unclassified Bacteria	2|Bacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
YHH1_k127_2679280_2	517417.Cpar_0177	2.322e-61	217.0	COG0087@1|root,COG0087@2|Bacteria,1FDRA@1090|Chlorobi	1090|Chlorobi	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
YHH1_k127_2679280_1	1089548.KI783301_gene3351	1.148e-63	224.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,3WERH@539002|Bacillales incertae sedis	91061|Bacilli	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YHH1_k127_2679280_4	1265505.ATUG01000001_gene3707	1.865e-17	85.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria,2MKJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
YHH1_k127_2679280_0	1191523.MROS_0213	4.946e-84	283.0	COG0090@1|root,COG0090@2|Bacteria	2|Bacteria	J	rRNA binding	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YHH1_k127_2679527_7	246197.MXAN_3068	1.547e-13	70.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2YX6I@29|Myxococcales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH1_k127_2679527_6	1280686.AUKE01000020_gene2756	4.489e-18	84.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,24QK0@186801|Clostridia,4C05C@830|Butyrivibrio	186801|Clostridia	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
YHH1_k127_2679527_9	207954.MED92_04552	2.491e-08	55.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XKF5@135619|Oceanospirillales	135619|Oceanospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
YHH1_k127_2679527_8	1379698.RBG1_1C00001G1611	1.802e-10	63.0	COG0690@1|root,COG0690@2|Bacteria,2NQ1C@2323|unclassified Bacteria	2|Bacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
YHH1_k127_2679527_2	1379698.RBG1_1C00001G1610	4.328e-78	264.0	COG0250@1|root,COG0250@2|Bacteria,2NPAP@2323|unclassified Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
YHH1_k127_2679527_3	338963.Pcar_0690	1.508e-58	205.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,42RE7@68525|delta/epsilon subdivisions,2WNAH@28221|Deltaproteobacteria,43UY3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein L11/L12	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
YHH1_k127_2679527_0	264732.Moth_2471	6.779e-86	289.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,42ETC@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
YHH1_k127_2679527_5	568816.Acin_2209	3.096e-32	132.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4H3ZQ@909932|Negativicutes	909932|Negativicutes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
YHH1_k127_2679527_4	547144.HydHO_0256	3.878e-36	140.0	COG0222@1|root,COG0222@2|Bacteria,2G42K@200783|Aquificae	200783|Aquificae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
YHH1_k127_2679527_1	880073.Calab_2119	2.508e-79	270.0	COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH1_k127_2693462_7	1123253.AUBD01000009_gene2309	1.851e-05	55.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S69B@1236|Gammaproteobacteria,1X7UQ@135614|Xanthomonadales	135614|Xanthomonadales	NU	General secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
YHH1_k127_2693462_8	1123377.AUIV01000012_gene770	6.65e-05	55.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S69B@1236|Gammaproteobacteria,1X6DG@135614|Xanthomonadales	135614|Xanthomonadales	NU	General secretion pathway protein	xpsG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
YHH1_k127_2693462_6	359.CN09_22170	6.01e-07	61.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2U7GY@28211|Alphaproteobacteria,4BFN6@82115|Rhizobiaceae	28211|Alphaproteobacteria	U	Type II secretion system protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
YHH1_k127_2693462_5	335543.Sfum_0102	1.802e-07	63.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria,2MS2E@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	PFAM type II secretion system protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
YHH1_k127_2693462_0	1379698.RBG1_1C00001G0675	8.686e-93	319.0	COG1748@1|root,COG1748@2|Bacteria,2NPF8@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
YHH1_k127_2693462_9	290402.Cbei_0436	0.0001358	49.0	COG0642@1|root,COG2205@2|Bacteria,1V129@1239|Firmicutes,25EBE@186801|Clostridia,36UJ9@31979|Clostridiaceae	186801|Clostridia	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YHH1_k127_2693462_3	1392488.JHZY01000002_gene929	8.839e-28	131.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1HWXR@117743|Flavobacteriia,2XIAX@283735|Leeuwenhoekiella	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2693462_2	234267.Acid_2404	4.061e-32	143.0	COG1409@1|root,COG1409@2|Bacteria,3Y7IU@57723|Acidobacteria	57723|Acidobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH1_k127_2693462_4	266748.HY04_14705	1.298e-11	78.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia,3ZRAU@59732|Chryseobacterium	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
YHH1_k127_2693462_1	1379698.RBG1_1C00001G1639	2.605e-86	297.0	COG0142@1|root,COG0142@2|Bacteria,2NP7G@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the FPP GGPP synthase family	ispB	GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	iYL1228.KPN_03597,ic_1306.c3945	polyprenyl_synt
YHH1_k127_2695071_0	329726.AM1_6085	1.672e-274	869.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria	1117|Cyanobacteria	K	ATP-dependent transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
YHH1_k127_2699242_0	1183438.GKIL_2944	3.61e-24	113.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG
YHH1_k127_2699242_1	755178.Cyan10605_1288	2.655e-18	98.0	COG0491@1|root,COG0491@2|Bacteria,1G400@1117|Cyanobacteria	1117|Cyanobacteria	S	Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH1_k127_2699242_2	1123037.AUDE01000025_gene3397	1.873e-08	62.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
YHH1_k127_2699727_10	886293.Sinac_4103	1.56e-15	81.0	296Z1@1|root,2ZU7K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2699727_11	1173023.KE650771_gene798	9.606e-09	65.0	COG1716@1|root,COG1716@2|Bacteria,1G7WQ@1117|Cyanobacteria	1117|Cyanobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2699727_6	637390.AFOH01000025_gene1036	1.515e-53	194.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
YHH1_k127_2699727_5	313612.L8106_05840	1.02e-70	244.0	COG4977@1|root,COG4977@2|Bacteria,1G48N@1117|Cyanobacteria,1HA7F@1150|Oscillatoriales	1117|Cyanobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
YHH1_k127_2699727_8	96561.Dole_0805	2.607e-26	117.0	COG1309@1|root,COG1309@2|Bacteria,1RCDH@1224|Proteobacteria,42VJ5@68525|delta/epsilon subdivisions,2WRC7@28221|Deltaproteobacteria,2MKUA@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_3,TetR_N
YHH1_k127_2699727_9	1123256.KB907936_gene2562	2.595e-18	98.0	COG1538@1|root,COG1538@2|Bacteria,1N23P@1224|Proteobacteria,1RMXN@1236|Gammaproteobacteria,1X8EQ@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH1_k127_2699727_7	96561.Dole_0807	1.433e-50	190.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM secretion protein HlyD family protein	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH1_k127_2699727_4	765420.OSCT_0042	3.397e-73	257.0	COG1131@1|root,COG1131@2|Bacteria,2G7Q5@200795|Chloroflexi,376MI@32061|Chloroflexia	32061|Chloroflexia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_2699727_1	1122176.KB903541_gene182	1.039e-86	293.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_2699727_2	96561.Dole_0810	1.929e-80	281.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria,2MJ2Q@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
YHH1_k127_2699727_3	96561.Dole_0811	5.472e-76	268.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria,2MJ98@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH1_k127_2699727_0	42256.RradSPS_2166	1.846e-99	333.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4CQ48@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
YHH1_k127_2723159_1	552398.HMPREF0866_00280	3.067e-05	55.0	COG1433@1|root,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,3WK5J@541000|Ruminococcaceae	186801|Clostridia	L	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
YHH1_k127_2723159_0	760568.Desku_2155	7.034e-136	443.0	COG3829@1|root,COG3829@2|Bacteria,1V0EF@1239|Firmicutes,24DXA@186801|Clostridia	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
YHH1_k127_2743710_1	880073.Calab_2217	5.105e-25	109.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
YHH1_k127_2743710_0	471852.Tcur_2047	1.933e-150	488.0	COG1249@1|root,COG1249@2|Bacteria,2GPG1@201174|Actinobacteria,4EI74@85012|Streptosporangiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH1_k127_2754220_2	289376.THEYE_A0572	1.925e-22	102.0	COG0474@1|root,COG0474@2|Bacteria,3J0YX@40117|Nitrospirae	40117|Nitrospirae	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
YHH1_k127_2754220_1	635013.TherJR_1742	2.473e-124	412.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,260PN@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
YHH1_k127_2754220_0	1379698.RBG1_1C00001G1066	1.084e-131	436.0	COG0260@1|root,COG0260@2|Bacteria,2NNKH@2323|unclassified Bacteria	2|Bacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1,3.4.11.5	ko:K01255,ko:K01259	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00135,R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
YHH1_k127_2764574_6	1094980.Mpsy_0015	4.425e-07	61.0	COG2133@1|root,COG3794@1|root,arCOG10180@1|root,arCOG02796@2157|Archaea,arCOG02929@2157|Archaea,arCOG10180@2157|Archaea,2XT1Q@28890|Euryarchaeota,2NADP@224756|Methanomicrobia	224756|Methanomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YHH1_k127_2764574_5	426114.THI_0985	3.495e-12	76.0	COG3794@1|root,COG3794@2|Bacteria,1RI9G@1224|Proteobacteria,2VX9Q@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
YHH1_k127_2764574_1	945713.IALB_2977	1.855e-56	207.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YHH1_k127_2764574_2	927658.AJUM01000034_gene466	8.462e-44	168.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
YHH1_k127_2764574_3	518766.Rmar_0610	1.258e-41	168.0	COG3034@1|root,COG3034@2|Bacteria,4NU5W@976|Bacteroidetes	976|Bacteroidetes	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
YHH1_k127_2764574_4	518766.Rmar_0609	2.151e-13	78.0	2FFT5@1|root,347QA@2|Bacteria,4P5W2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398
YHH1_k127_2764574_0	204669.Acid345_2712	5.738e-123	411.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria,2JJ6B@204432|Acidobacteriia	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
YHH1_k127_2774201_0	86416.Clopa_0047	1.29e-159	528.0	COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,24CJP@186801|Clostridia,36GCY@31979|Clostridiaceae	186801|Clostridia	Q	PFAM Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
YHH1_k127_2774201_1	1191523.MROS_2238	1.779e-24	120.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	CBM_6,fn3
YHH1_k127_2780821_7	553175.POREN0001_1874	1.419e-05	54.0	COG1286@1|root,COG1286@2|Bacteria	2|Bacteria	S	toxin biosynthetic process	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
YHH1_k127_2780821_0	1379698.RBG1_1C00001G1551	2.458e-291	908.0	COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria	2|Bacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH1_k127_2780821_4	1379698.RBG1_1C00001G1845	3.958e-24	107.0	COG0261@1|root,COG0261@2|Bacteria,2NPSX@2323|unclassified Bacteria	2|Bacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
YHH1_k127_2780821_1	1379698.RBG1_1C00001G1846	1.62e-188	618.0	COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YHH1_k127_2780821_6	1379698.RBG1_1C00001G1847	1.239e-18	93.0	COG2825@1|root,COG2825@2|Bacteria,2NQ6C@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
YHH1_k127_2780821_2	671143.DAMO_1651	3.168e-86	297.0	COG1044@1|root,COG1044@2|Bacteria,2NNSF@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
YHH1_k127_2780821_3	1396.DJ87_2096	2.752e-31	133.0	COG0500@1|root,COG2226@2|Bacteria,1V04P@1239|Firmicutes,4HEGX@91061|Bacilli,1ZCVB@1386|Bacillus	91061|Bacilli	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH1_k127_2780821_5	1379698.RBG1_1C00001G1794	9.377e-19	89.0	COG4448@1|root,COG4448@2|Bacteria	2|Bacteria	E	L-asparaginase II	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase_II
YHH1_k127_2790429_0	1123392.AQWL01000003_gene283	0.0	1050.0	COG0286@1|root,COG0286@2|Bacteria,1MWUJ@1224|Proteobacteria,2VIQS@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
YHH1_k127_2790429_1	292415.Tbd_1488	4.575e-89	296.0	2E4FX@1|root,32ZB2@2|Bacteria,1NCDK@1224|Proteobacteria,2VXCG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2812179_11	1121406.JAEX01000002_gene1142	3.868e-33	133.0	COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria,42SIB@68525|delta/epsilon subdivisions,2WPCP@28221|Deltaproteobacteria,2ME8A@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH1_k127_2812179_8	1122201.AUAZ01000008_gene408	2.942e-80	271.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,463YM@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
YHH1_k127_2812179_9	383372.Rcas_0300	4.366e-54	207.0	COG0720@1|root,COG0720@2|Bacteria,2G992@200795|Chloroflexi,3753G@32061|Chloroflexia	32061|Chloroflexia	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
YHH1_k127_2812179_10	324602.Caur_2642	4.16e-49	183.0	COG4221@1|root,COG4221@2|Bacteria,2GBSD@200795|Chloroflexi,375PC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH1_k127_2812179_2	468059.AUHA01000002_gene43	9.4e-213	676.0	COG3186@1|root,COG3186@2|Bacteria,4NEX5@976|Bacteroidetes,1IQDN@117747|Sphingobacteriia	976|Bacteroidetes	E	Biopterin-dependent aromatic amino acid hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
YHH1_k127_2812179_4	945713.IALB_1673	6.913e-156	499.0	COG3185@1|root,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
YHH1_k127_2812179_3	945713.IALB_1672	1.206e-164	533.0	COG3508@1|root,COG3508@2|Bacteria	2|Bacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
YHH1_k127_2812179_7	1267535.KB906767_gene5520	6.144e-95	324.0	COG0079@1|root,COG0079@2|Bacteria,3Y4H9@57723|Acidobacteria,2JMT4@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_2812179_5	945713.IALB_1671	2.043e-132	430.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	fahA2	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
YHH1_k127_2812179_6	945713.IALB_1670	1.301e-106	355.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
YHH1_k127_2812179_1	402881.Plav_0554	6.623e-227	724.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,2TRND@28211|Alphaproteobacteria,1JNP8@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	Acetyl-coenzyme A synthetase N-terminus	acsA1	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YHH1_k127_2812179_0	1195246.AGRI_15866	1.514e-310	981.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,1RRK7@1236|Gammaproteobacteria,46458@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
YHH1_k127_2812179_12	283942.IL1716	1.34e-14	76.0	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,1RZEJ@1236|Gammaproteobacteria,2QFAR@267893|Idiomarinaceae	1236|Gammaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YHH1_k127_2816521_4	358681.BBR47_08580	3.897e-17	87.0	COG0454@1|root,COG0456@2|Bacteria,1V4GU@1239|Firmicutes,4HQNT@91061|Bacilli,26XKA@186822|Paenibacillaceae	91061|Bacilli	K	GCN5 family acetyltransferase	-	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
YHH1_k127_2816521_3	1216932.CM240_2866	6.232e-19	97.0	COG1852@1|root,COG1852@2|Bacteria,1UZ1X@1239|Firmicutes,24A38@186801|Clostridia,36EPT@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116
YHH1_k127_2816521_2	1196029.ALIM01000052_gene99	1.59e-27	116.0	COG2314@1|root,COG2314@2|Bacteria,1VESS@1239|Firmicutes,4HP3D@91061|Bacilli,1ZJDP@1386|Bacillus	91061|Bacilli	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2816521_1	640512.BC1003_0581	3.21e-56	209.0	COG2267@1|root,COG2267@2|Bacteria,1MW9H@1224|Proteobacteria,2VNQG@28216|Betaproteobacteria,1KFHR@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YHH1_k127_2816521_0	1274374.CBLK010000086_gene4587	4.473e-67	237.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,26RR9@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
YHH1_k127_2816521_5	743719.PaelaDRAFT_2955	1.154e-07	60.0	COG2318@1|root,COG2318@2|Bacteria,1VCAQ@1239|Firmicutes,4HMFF@91061|Bacilli,275XD@186822|Paenibacillaceae	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH1_k127_2818552_1	33876.JNXY01000041_gene6496	7.555e-44	168.0	2EZGX@1|root,2ZBAK@2|Bacteria,2IEK8@201174|Actinobacteria,4DI24@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2818552_0	765911.Thivi_0478	1.703e-105	349.0	COG3039@1|root,COG3039@2|Bacteria,1N88K@1224|Proteobacteria	1224|Proteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_3
YHH1_k127_2888300_2	1453505.JASY01000008_gene634	4.385e-37	147.0	COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,1I1UF@117743|Flavobacteriia,2NVBJ@237|Flavobacterium	976|Bacteroidetes	Q	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2888300_4	1094466.KQS_07925	4.404e-31	126.0	COG0640@1|root,COG0640@2|Bacteria,4NSAV@976|Bacteroidetes,1I3VH@117743|Flavobacteriia,2NWRE@237|Flavobacterium	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
YHH1_k127_2888300_1	1227739.Hsw_0573	5.785e-46	172.0	2E3VP@1|root,32YSV@2|Bacteria,4NV28@976|Bacteroidetes,47S3V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2888300_6	1123234.AUKI01000020_gene915	4.481e-13	74.0	2EEZ4@1|root,338SA@2|Bacteria,4NW9N@976|Bacteroidetes,1IBNB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2888300_0	929556.Solca_3116	2.281e-96	338.0	COG1835@1|root,COG1835@2|Bacteria,4NMNZ@976|Bacteroidetes,1IQXU@117747|Sphingobacteriia	976|Bacteroidetes	I	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
YHH1_k127_2888300_8	68199.JNZO01000009_gene5087	0.0003847	46.0	2EKJY@1|root,33E9T@2|Bacteria,2IQW9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
YHH1_k127_2888300_7	1288494.EBAPG3_9990	4.155e-07	54.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHER@28216|Betaproteobacteria,372VZ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Integrase, catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve_3
YHH1_k127_2888300_3	323848.Nmul_A1923	6.703e-35	138.0	COG1873@1|root,COG1873@2|Bacteria,1QTWZ@1224|Proteobacteria,2VT3J@28216|Betaproteobacteria,3730X@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
YHH1_k127_2888300_5	1123393.KB891330_gene876	2.31e-24	109.0	2B4TG@1|root,31XK1@2|Bacteria,1RIY8@1224|Proteobacteria,2VTMB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2890902_2	324925.Ppha_2558	1.967e-23	101.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
YHH1_k127_2890902_1	237368.SCABRO_01718	2.731e-43	161.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH1_k127_2890902_0	234267.Acid_2079	4.213e-54	201.0	COG1621@1|root,COG1621@2|Bacteria,3Y45X@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 32	-	-	3.2.1.26,3.2.1.80	ko:K01193,ko:K03332	ko00051,ko00052,ko00500,ko01100,map00051,map00052,map00500,map01100	-	R00801,R00802,R00879,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
YHH1_k127_2894793_1	1123487.KB892857_gene2538	1.501e-77	270.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria,2KUD8@206389|Rhodocyclales	28216|Betaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
YHH1_k127_2894793_0	673860.AciM339_1019	1.461e-186	595.0	COG1690@1|root,arCOG04246@2157|Archaea,2XTIC@28890|Euryarchaeota,3F2GK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	tRNA-splicing ligase RtcB	rtcB	GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Intein_splicing,LAGLIDADG_3,RtcB
YHH1_k127_2894793_3	273057.SSO0690	5.293e-21	97.0	COG1371@1|root,arCOG04055@2157|Archaea,2XQYK@28889|Crenarchaeota	28889|Crenarchaeota	J	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently	-	-	-	-	-	-	-	-	-	-	-	-	Archease
YHH1_k127_2894793_2	292415.Tbd_2287	3.9e-43	160.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VQQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
YHH1_k127_2898241_4	1397696.KK211189_gene2120	2.738e-06	50.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,3WEAI@539002|Bacillales incertae sedis	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YHH1_k127_2898241_2	1382306.JNIM01000001_gene766	6.296e-117	396.0	COG0166@1|root,COG0166@2|Bacteria,2G67J@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
YHH1_k127_2898241_0	515635.Dtur_0183	2.299e-208	666.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
YHH1_k127_2898241_3	309801.trd_1142	6.77e-110	365.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,27XH5@189775|Thermomicrobia	189775|Thermomicrobia	C	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
YHH1_k127_2898241_1	1051632.TPY_1049	2.426e-173	560.0	COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,24939@186801|Clostridia	186801|Clostridia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
YHH1_k127_2947644_0	880073.Calab_1754	1.49e-245	789.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.4,3.4.21.66	ko:K01179,ko:K08651	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Autotransporter,PKD,Peptidase_S8,Peptidase_S8_N,fn3
YHH1_k127_2947644_2	1379698.RBG1_1C00001G1218	2.332e-105	377.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
YHH1_k127_2947644_5	234267.Acid_3432	1.574e-71	262.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
YHH1_k127_2947644_4	1047013.AQSP01000123_gene1542	5.054e-82	290.0	COG2204@1|root,COG2204@2|Bacteria,2NP3X@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_2947644_6	304371.MCP_1615	2.596e-54	219.0	COG2202@1|root,arCOG02353@1|root,arCOG02353@2157|Archaea,arCOG06515@2157|Archaea,arCOG06918@2157|Archaea	2157|Archaea	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YHH1_k127_2947644_1	398767.Glov_1032	3.285e-150	486.0	COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,42MAE@68525|delta/epsilon subdivisions,2WKFF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Xanthine uracil vitamin C permease	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
YHH1_k127_2947644_3	671143.DAMO_2569	8.153e-99	336.0	COG0530@1|root,COG0530@2|Bacteria,2NPSH@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
YHH1_k127_2947644_7	665571.STHERM_c07970	1.838e-36	147.0	COG0517@1|root,COG1762@1|root,COG0517@2|Bacteria,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN_1	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	CBS,HTH_17,PTS_EIIA_2
YHH1_k127_2951305_0	1206743.BAGM01000052_gene1354	1.31e-56	215.0	COG1807@1|root,COG1807@2|Bacteria,2IASE@201174|Actinobacteria,4FZQ9@85025|Nocardiaceae	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2951305_1	1268240.ATFI01000008_gene2121	1.235e-05	57.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,2FN57@200643|Bacteroidia,4APC7@815|Bacteroidaceae	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
YHH1_k127_2961141_5	1379698.RBG1_1C00001G1702	2.969e-08	55.0	COG1595@1|root,COG1595@2|Bacteria,2NR5Q@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YHH1_k127_2961141_0	1353537.TP2_00340	2.45e-167	551.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2XM0J@285107|Thioclava	28211|Alphaproteobacteria	P	Heavy-metal-associated domain	actP	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
YHH1_k127_2961141_1	221288.JH992901_gene3454	3.612e-92	310.0	COG0412@1|root,COG0412@2|Bacteria,1G4HV@1117|Cyanobacteria	1117|Cyanobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
YHH1_k127_2961141_3	880072.Desac_0212	6.766e-58	205.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria,2MRIV@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Large-conductance mechanosensitive channel, MscL	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
YHH1_k127_2961141_4	1305836.AXVE01000012_gene42	6.749e-16	81.0	COG0346@1|root,COG0346@2|Bacteria,1W3B2@1239|Firmicutes,4I26F@91061|Bacilli,26HZ5@186818|Planococcaceae	91061|Bacilli	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2961141_2	1237149.C900_05249	7.517e-65	229.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PK1@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
YHH1_k127_2965154_0	379066.GAU_2496	1.825e-67	246.0	COG3437@1|root,COG3437@2|Bacteria,1ZUP1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3013391_0	7719.XP_002129413.1	6.021e-17	93.0	28KV9@1|root,2QTBN@2759|Eukaryota,38DU3@33154|Opisthokonta,3BBCZ@33208|Metazoa,3CTUR@33213|Bilateria,485U4@7711|Chordata	33208|Metazoa	S	hydrolase activity	TMEM62	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH1_k127_3013391_1	247490.KSU1_D0788	5.575e-05	51.0	COG0457@1|root,COG0457@2|Bacteria	247490.KSU1_D0788|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3024668_5	1163407.UU7_11502	7.182e-22	104.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1X5DD@135614|Xanthomonadales	135614|Xanthomonadales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
YHH1_k127_3024668_3	1125863.JAFN01000001_gene3050	6.826e-34	136.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
YHH1_k127_3024668_1	1379698.RBG1_1C00001G0500	3.01e-99	339.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
YHH1_k127_3024668_6	1047013.AQSP01000135_gene1614	2.311e-07	61.0	COG0810@1|root,COG0810@2|Bacteria,2NQ3G@2323|unclassified Bacteria	2|Bacteria	M	TonB C terminal	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
YHH1_k127_3024668_4	1379698.RBG1_1C00001G0498	3.786e-29	122.0	COG0848@1|root,COG0848@2|Bacteria,2NPWJ@2323|unclassified Bacteria	2|Bacteria	U	Biopolymer transport protein ExbD/TolR	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
YHH1_k127_3024668_2	1379698.RBG1_1C00001G0497	1.075e-41	162.0	COG0811@1|root,COG0811@2|Bacteria,2NPFR@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	tolQ	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
YHH1_k127_3024668_0	1379698.RBG1_1C00001G0120	3.942e-112	370.0	28II6@1|root,2Z8JB@2|Bacteria,2NNT1@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3050718_1	292415.Tbd_2287	4.098e-110	359.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VQQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
YHH1_k127_3050718_7	1123503.KB908056_gene1309	1.329e-21	108.0	2941A@1|root,2ZRG3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3050718_9	28444.JODQ01000002_gene4195	3.924e-21	106.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4EHA8@85012|Streptosporangiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YHH1_k127_3050718_2	317936.Nos7107_4209	1.009e-79	274.0	COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
YHH1_k127_3050718_3	65093.PCC7418_0889	1.753e-57	212.0	COG2905@1|root,COG2905@2|Bacteria,1GPZ1@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
YHH1_k127_3050718_10	1120965.AUBV01000006_gene2377	8.318e-20	94.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH1_k127_3050718_5	552811.Dehly_1481	2.861e-44	168.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YHH1_k127_3050718_0	1210884.HG799463_gene9843	0.0	1056.0	COG3256@1|root,COG3256@2|Bacteria,2J2IF@203682|Planctomycetes	203682|Planctomycetes	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
YHH1_k127_3050718_6	411154.GFO_1672	5.972e-31	134.0	29FE7@1|root,302BX@2|Bacteria,4NMTG@976|Bacteroidetes,1I1WT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3050718_4	1379698.RBG1_1C00001G0713	7.053e-46	177.0	COG4221@1|root,COG4221@2|Bacteria,2NPJV@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
YHH1_k127_3050718_8	696281.Desru_1310	2.095e-21	94.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,260YV@186807|Peptococcaceae	186801|Clostridia	C	PFAM isocitrate isopropylmalate dehydrogenase	icd	-	1.1.1.41,1.1.1.83,1.1.1.93,4.1.1.73	ko:K00030,ko:K07246	ko00020,ko00630,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00650,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00215,R00709,R01751,R02545,R06180	RC00084,RC00105,RC00114,RC00594	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH1_k127_3056735_2	665571.STHERM_c10790	1.016e-06	60.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
YHH1_k127_3056735_3	1500894.JQNN01000001_gene2625	0.0003443	52.0	COG0810@1|root,COG0810@2|Bacteria,1RJRA@1224|Proteobacteria,2VTFA@28216|Betaproteobacteria,4749W@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH1_k127_3056735_1	1122243.KB903809_gene1097	2.892e-09	63.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,3NK24@468|Moraxellaceae	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	tolR	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
YHH1_k127_3056735_4	113395.AXAI01000006_gene1770	0.0003671	48.0	COG0848@1|root,COG0848@2|Bacteria,1RDJZ@1224|Proteobacteria,2U77T@28211|Alphaproteobacteria,3JZ71@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	U	Outer membrane transport energization protein ExbD	exbD	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
YHH1_k127_3056735_0	436717.AOLE_10875	5.694e-22	106.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,3NKFJ@468|Moraxellaceae	1236|Gammaproteobacteria	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH1_k127_310431_0	1379698.RBG1_1C00001G0146	5.224e-69	244.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
YHH1_k127_310431_3	1379698.RBG1_1C00001G0147	1.899e-25	108.0	COG0636@1|root,COG0636@2|Bacteria,2NQ21@2323|unclassified Bacteria	2|Bacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
YHH1_k127_310431_1	1379698.RBG1_1C00001G0148	2.193e-41	158.0	COG0711@1|root,COG0711@2|Bacteria,2NQ34@2323|unclassified Bacteria	2|Bacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
YHH1_k127_310431_2	477974.Daud_2140	8.978e-28	119.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,261U6@186807|Peptococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
YHH1_k127_3117698_2	748247.AZKH_3372	2.403e-16	78.0	COG5450@1|root,COG5450@2|Bacteria,1N76R@1224|Proteobacteria,2VWE3@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
YHH1_k127_3117698_1	748247.AZKH_3373	5.75e-62	217.0	COG1487@1|root,COG1487@2|Bacteria,1PUQH@1224|Proteobacteria,2WAVZ@28216|Betaproteobacteria,2KZEV@206389|Rhodocyclales	206389|Rhodocyclales	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3117698_0	375286.mma_0961	3.896e-161	511.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VQF1@28216|Betaproteobacteria,478J0@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Product type h extrachromosomal origin	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
YHH1_k127_3126128_3	880072.Desac_2548	4.198e-33	130.0	COG0500@1|root,COG2226@2|Bacteria,1QUKK@1224|Proteobacteria,42STK@68525|delta/epsilon subdivisions,2WP81@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH1_k127_3126128_1	243231.GSU3274	2.152e-44	174.0	2BVK0@1|root,32QXS@2|Bacteria,1RKSK@1224|Proteobacteria,42ZW3@68525|delta/epsilon subdivisions,2WVED@28221|Deltaproteobacteria,43UVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3126128_2	243231.GSU3268	2.951e-37	143.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,43UAC@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-2	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
YHH1_k127_3126128_0	1121129.KB903359_gene1209	8.361e-166	533.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,2FMEC@200643|Bacteroidia,22WNC@171551|Porphyromonadaceae	976|Bacteroidetes	P	Calcium-translocating P-type ATPase, PMCA-type	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
YHH1_k127_3126128_4	521011.Mpal_1924	1.797e-17	85.0	COG2172@1|root,arCOG06892@2157|Archaea,2Y3FK@28890|Euryarchaeota	28890|Euryarchaeota	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
YHH1_k127_3196003_0	945713.IALB_0724	1.12e-155	504.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	ccoG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
YHH1_k127_3196003_1	1229276.DI53_0449	6.889e-30	119.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
YHH1_k127_3201487_4	633149.Bresu_2616	2.107e-06	52.0	2A0YP@1|root,30P3X@2|Bacteria,1NDHJ@1224|Proteobacteria,2UID9@28211|Alphaproteobacteria,2KIPX@204458|Caulobacterales	204458|Caulobacterales	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
YHH1_k127_3201487_2	1122604.JONR01000074_gene717	4.898e-28	117.0	COG4994@1|root,COG4994@2|Bacteria,1N6US@1224|Proteobacteria,1SD32@1236|Gammaproteobacteria,1X8UC@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
YHH1_k127_3201487_0	56780.SYN_00568	8.357e-96	344.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
YHH1_k127_3201487_3	759914.BP951000_0647	9.533e-07	56.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	ttg2E	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043856,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	3.5.1.2	ko:K01425,ko:K02066,ko:K03090,ko:K04749,ko:K06378,ko:K07122	ko00220,ko00250,ko00471,ko01100,ko02010,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map02010,map04724,map04727,map04964,map05206,map05230	M00210,M00669,M00670	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko00002,ko01000,ko02000,ko03021	3.A.1.27,3.A.1.27.3	-	-	MEDS,STAS,STAS_2
YHH1_k127_3201487_5	1173028.ANKO01000056_gene2171	0.0007406	50.0	COG2172@1|root,COG2172@2|Bacteria,1G64E@1117|Cyanobacteria,1HCFR@1150|Oscillatoriales	1117|Cyanobacteria	T	Anti-Sigma regulatory factor (Ser Thr protein kinase)	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
YHH1_k127_3201487_1	880073.Calab_0681	1.201e-50	196.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	pkn5	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1
YHH1_k127_3201487_6	3641.EOY16282	0.0007619	44.0	COG0457@1|root,KOG0553@2759|Eukaryota,37NAY@33090|Viridiplantae,3G923@35493|Streptophyta	35493|Streptophyta	S	Small glutamine-rich tetratricopeptide repeat-containing protein	-	GO:0003674,GO:0005488,GO:0005515,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006996,GO:0007029,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010033,GO:0010243,GO:0010256,GO:0010498,GO:0010605,GO:0016043,GO:0019222,GO:0019538,GO:0019941,GO:0030162,GO:0030163,GO:0030433,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0032268,GO:0032269,GO:0032434,GO:0032435,GO:0033036,GO:0033365,GO:0033554,GO:0034613,GO:0034976,GO:0036503,GO:0042176,GO:0042177,GO:0042221,GO:0043161,GO:0043170,GO:0043621,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045048,GO:0045184,GO:0045861,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051205,GO:0051234,GO:0051246,GO:0051248,GO:0051603,GO:0051641,GO:0051716,GO:0060255,GO:0061024,GO:0061136,GO:0065007,GO:0070727,GO:0071704,GO:0071816,GO:0071840,GO:0072657,GO:0080090,GO:0080134,GO:0080135,GO:0090150,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901799,GO:1903050,GO:1903051,GO:1903069,GO:1903070,GO:1903362,GO:1903363,GO:1903573,GO:1904292,GO:1904293,GO:1905897,GO:2000058,GO:2000059	-	ko:K16365	-	-	-	-	ko00000,ko04147,ko04516	-	-	-	SGTA_dimer,TPR_1,TPR_11,TPR_17,TPR_2
YHH1_k127_3201615_0	518766.Rmar_2323	1.887e-41	156.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1FIMG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
YHH1_k127_3201615_1	880073.Calab_3481	1.071e-36	160.0	COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
YHH1_k127_3201615_2	1028801.RG1141_PA06390	5.012e-08	58.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,2U57Y@28211|Alphaproteobacteria,4BIR6@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6
YHH1_k127_32239_0	1122179.KB890415_gene1985	5.364e-16	80.0	2A0AF@1|root,2ZQ9W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_32239_2	313589.JNB_16053	1.346e-06	56.0	COG2963@1|root,COG2963@2|Bacteria,2IJ0M@201174|Actinobacteria,4FIH3@85021|Intrasporangiaceae	201174|Actinobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
YHH1_k127_32239_1	398767.Glov_0520	1.175e-08	55.0	COG3464@1|root,COG3464@2|Bacteria,1R4DH@1224|Proteobacteria,43AQ4@68525|delta/epsilon subdivisions,2X63W@28221|Deltaproteobacteria,43W3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM transposase IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
YHH1_k127_3232145_1	1121405.dsmv_1140	9.975e-95	314.0	COG0569@1|root,COG0569@2|Bacteria,1R7KM@1224|Proteobacteria,42PJH@68525|delta/epsilon subdivisions,2WMZT@28221|Deltaproteobacteria,2MJ9H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
YHH1_k127_3232145_0	525897.Dbac_0338	6.329e-173	554.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,42MBI@68525|delta/epsilon subdivisions,2WIZ9@28221|Deltaproteobacteria,2M843@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Cation transporter	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
YHH1_k127_3232145_2	525897.Dbac_0337	5.648e-28	120.0	28TP1@1|root,2ZFWF@2|Bacteria,1P93F@1224|Proteobacteria,4326I@68525|delta/epsilon subdivisions,2WY7F@28221|Deltaproteobacteria,2MFGS@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3247341_5	484019.THA_1825	2.867e-82	280.0	COG0176@1|root,COG0176@2|Bacteria,2GC05@200918|Thermotogae	200918|Thermotogae	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0295	TAL_FSA
YHH1_k127_3247341_7	865861.AZSU01000001_gene53	2.589e-48	182.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,36DP0@31979|Clostridiaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
YHH1_k127_3247341_8	1246484.D479_09110	1.766e-43	171.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,3NDE6@45667|Halobacillus	91061|Bacilli	U	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
YHH1_k127_3247341_1	1379270.AUXF01000004_gene3268	2.859e-149	501.0	COG0370@1|root,COG0370@2|Bacteria,1ZT1I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
YHH1_k127_3247341_12	1284679.HMPREF1626_04490	1.476e-13	73.0	COG1918@1|root,COG1918@2|Bacteria,2GX6H@201174|Actinobacteria,4D611@85005|Actinomycetales	201174|Actinobacteria	P	FeoA domain protein	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
YHH1_k127_3247341_13	1202532.FF52_00875	0.0001799	49.0	COG2010@1|root,COG2010@2|Bacteria,4NXZT@976|Bacteroidetes,1I673@117743|Flavobacteriia,2NX4B@237|Flavobacterium	976|Bacteroidetes	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHC
YHH1_k127_3247341_9	563192.HMPREF0179_03579	2.976e-27	116.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42SII@68525|delta/epsilon subdivisions,2WPJG@28221|Deltaproteobacteria,2MGU2@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH1_k127_3247341_6	309799.DICTH_0455	5.956e-60	236.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,FlgD_ig,Peptidase_M6
YHH1_k127_3247341_11	1379698.RBG1_1C00001G0428	2.206e-19	104.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	B_lectin,FlgD_ig,PQQ_2,PQQ_3,Pkinase,VCBS
YHH1_k127_3247341_2	1379698.RBG1_1C00001G0069	1.943e-118	417.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NRP6@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CHU_C,FlgD_ig,PKD,Peptidase_S8
YHH1_k127_3247341_3	1379698.RBG1_1C00001G1816	3.928e-92	329.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
YHH1_k127_3247341_10	1379698.RBG1_1C00001G1817	5.367e-27	128.0	COG0308@1|root,COG0308@2|Bacteria,2NRIZ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Cofac_haem_bdg,NAAA-beta,Peptidase_M1,Phospholip_B
YHH1_k127_3247341_4	1379698.RBG1_1C00001G1818	3.911e-89	305.0	COG2067@1|root,COG2067@2|Bacteria,2NR34@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3247341_0	1379698.RBG1_1C00001G1820	5.248e-239	775.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH1_k127_3278966_0	518766.Rmar_0089	2.699e-190	619.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_3316735_0	264732.Moth_1443	3.29e-33	135.0	COG0500@1|root,COG2226@2|Bacteria,1V6EF@1239|Firmicutes,24JZ4@186801|Clostridia,42GNV@68295|Thermoanaerobacterales	186801|Clostridia	Q	Methyltransferase type 11	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
YHH1_k127_3316735_1	401526.TcarDRAFT_1265	2.68e-31	129.0	298ZI@1|root,2ZW3A@2|Bacteria,1V7FU@1239|Firmicutes,4H5FQ@909932|Negativicutes	909932|Negativicutes	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
YHH1_k127_3347471_14	891968.Anamo_1585	8.904e-22	97.0	COG0438@1|root,COG0438@2|Bacteria,3TC5G@508458|Synergistetes	508458|Synergistetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3347471_0	891968.Anamo_1584	1.195e-199	628.0	COG0438@1|root,COG0438@2|Bacteria,3TAFG@508458|Synergistetes	508458|Synergistetes	H	PFAM glycosyl transferase group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
YHH1_k127_3347471_3	290397.Adeh_0511	9.546e-96	329.0	COG0475@1|root,COG0475@2|Bacteria,1RA3J@1224|Proteobacteria,43EWJ@68525|delta/epsilon subdivisions,2WTW1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YHH1_k127_3347471_13	1219045.BV98_001748	5.859e-22	103.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2U5XG@28211|Alphaproteobacteria,2K470@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
YHH1_k127_3347471_11	1232410.KI421421_gene3803	4.456e-35	143.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,42R0Q@68525|delta/epsilon subdivisions,2WN87@28221|Deltaproteobacteria,43S55@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
YHH1_k127_3347471_12	509635.N824_14825	5.273e-30	127.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,1IS2G@117747|Sphingobacteriia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
YHH1_k127_3347471_2	1408473.JHXO01000010_gene3756	6.031e-138	447.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,2FNQP@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
YHH1_k127_3347471_1	926569.ANT_23280	2.085e-153	498.0	COG0520@1|root,COG0520@2|Bacteria,2G85X@200795|Chloroflexi	200795|Chloroflexi	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YHH1_k127_3347471_5	880073.Calab_0603	2.351e-72	259.0	COG0438@1|root,COG0438@2|Bacteria,2NQ20@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_3347471_15	880073.Calab_3408	5.932e-17	87.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,SLH
YHH1_k127_3347471_7	926550.CLDAP_26360	2.103e-66	246.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3347471_4	926550.CLDAP_26360	1.374e-77	283.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3347471_16	1274524.BSONL12_04269	4.035e-13	77.0	COG1514@1|root,COG1514@2|Bacteria,1V2F3@1239|Firmicutes,4HG6P@91061|Bacilli,1ZG9R@1386|Bacillus	91061|Bacilli	J	Belongs to the 2H phosphoesterase superfamily. YjcG family	yjcG	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
YHH1_k127_3347471_9	1415780.JPOG01000001_gene658	8.134e-53	204.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1X5D2@135614|Xanthomonadales	135614|Xanthomonadales	M	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
YHH1_k127_3347471_6	1379698.RBG1_1C00001G0322	2.411e-71	259.0	COG2385@1|root,COG2385@2|Bacteria,2NPRR@2323|unclassified Bacteria	2|Bacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
YHH1_k127_3347471_8	1356852.N008_11525	1.399e-60	224.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,47NI9@768503|Cytophagia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
YHH1_k127_3347471_10	1071073.KI530551_gene3776	3.679e-40	157.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,1ZCGR@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
YHH1_k127_3361206_4	706587.Desti_2670	2.266e-47	175.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria,2MQSD@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
YHH1_k127_3361206_5	1379281.AVAG01000009_gene628	1.206e-41	157.0	arCOG10385@1|root,32SEM@2|Bacteria,1N1IG@1224|Proteobacteria,42TMW@68525|delta/epsilon subdivisions,2WQBW@28221|Deltaproteobacteria,2MC03@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	dsrJ	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3361206_0	264732.Moth_1606	3.895e-281	871.0	COG0247@1|root,COG0247@2|Bacteria,1TSC1@1239|Firmicutes,24B10@186801|Clostridia,42FPP@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	hmeD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
YHH1_k127_3361206_1	485915.Dret_0235	1.374e-134	436.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,42MZU@68525|delta/epsilon subdivisions,2WKKU@28221|Deltaproteobacteria,2M7X4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
YHH1_k127_3361206_6	335543.Sfum_1145	6.156e-36	143.0	2CDHP@1|root,32RXU@2|Bacteria,1N1BP@1224|Proteobacteria,42TPT@68525|delta/epsilon subdivisions,2WQE6@28221|Deltaproteobacteria,2MRXY@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	RsbT co-antagonist protein rsbRD N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
YHH1_k127_3361206_2	1210884.HG799465_gene11716	5.993e-124	421.0	COG3975@1|root,COG3975@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
YHH1_k127_3361206_3	1499967.BAYZ01000156_gene556	3.333e-72	248.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K20444	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
YHH1_k127_3364508_2	1379698.RBG1_1C00001G1882	9.41e-122	420.0	COG1138@1|root,COG1138@2|Bacteria,2NNYV@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
YHH1_k127_3364508_6	1379698.RBG1_1C00001G0421	1.76e-21	99.0	COG2332@1|root,COG2332@2|Bacteria,2NQ2A@2323|unclassified Bacteria	2|Bacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
YHH1_k127_3364508_4	1379698.RBG1_1C00001G0422	4.996e-64	226.0	COG0755@1|root,COG0755@2|Bacteria,2NPGT@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmC	GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
YHH1_k127_3364508_1	340177.Cag_1780	1.562e-161	518.0	COG0205@1|root,COG0205@2|Bacteria,1FEH2@1090|Chlorobi	1090|Chlorobi	G	PFAM phosphofructokinase	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
YHH1_k127_3364508_7	873533.HMPREF0663_10287	8.05e-18	91.0	2FJRB@1|root,34BE7@2|Bacteria,4P5QR@976|Bacteroidetes,2FYTE@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3364508_8	1230476.C207_06807	1.36e-17	84.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria,3JZ7D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
YHH1_k127_3364508_0	1192034.CAP_3780	1.368e-177	566.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P6D@68525|delta/epsilon subdivisions,2WM1P@28221|Deltaproteobacteria,2YUD4@29|Myxococcales	28221|Deltaproteobacteria	T	DNA-binding response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_3364508_3	448385.sce7800	2.911e-94	327.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43AQK@68525|delta/epsilon subdivisions,2X64H@28221|Deltaproteobacteria,2Z00K@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YHH1_k127_3364508_5	403833.Pmob_0014	1.86e-60	226.0	COG0534@1|root,COG0534@2|Bacteria,2GCPB@200918|Thermotogae	200918|Thermotogae	V	TIGRFAM MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
YHH1_k127_3367847_1	880073.Calab_3099	7.424e-162	525.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
YHH1_k127_3367847_0	1340493.JNIF01000003_gene2186	2.869e-186	618.0	COG1026@1|root,COG1026@2|Bacteria	2|Bacteria	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
YHH1_k127_3370139_3	1379698.RBG1_1C00001G1367	6.272e-55	199.0	COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria	2|Bacteria	V	COGs COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_3370139_2	1379698.RBG1_1C00001G1366	2.605e-89	309.0	COG0577@1|root,COG0577@2|Bacteria,2NQMU@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_3370139_0	234267.Acid_7937	8.274e-101	333.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_3370139_1	1379698.RBG1_1C00001G1364	1.532e-97	334.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
YHH1_k127_3370139_4	215803.DB30_3564	1.273e-31	139.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2X5KQ@28221|Deltaproteobacteria,2YYUS@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
YHH1_k127_3392816_2	1121439.dsat_1312	7.578e-31	134.0	COG0308@1|root,COG0308@2|Bacteria,1PEPK@1224|Proteobacteria,42NJ8@68525|delta/epsilon subdivisions,2WM57@28221|Deltaproteobacteria,2MA7F@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Peptidase_M1
YHH1_k127_3392816_0	1048983.EL17_23575	1.391e-63	231.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH1_k127_3392816_1	1185876.BN8_00877	4.936e-38	157.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47KZI@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_3392816_3	1121456.ATVA01000019_gene1268	1.229e-27	126.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_4,PAS_9,dCache_1
YHH1_k127_3414797_7	1379698.RBG1_1C00001G0052	1.543e-55	200.0	COG1150@1|root,COG1150@2|Bacteria,2NQ2K@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hdrC	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389,ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3424	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8,Fer4_9
YHH1_k127_3414797_5	1379698.RBG1_1C00001G0051	2.166e-100	335.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
YHH1_k127_3414797_4	693661.Arcve_1567	1.747e-101	340.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
YHH1_k127_3414797_9	1499967.BAYZ01000171_gene5565	4.05e-43	166.0	COG1148@1|root,COG1905@1|root,COG1148@2|Bacteria,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria	2|Bacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	bamG	-	1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00334,ko:K03388	ko00190,ko00680,ko01100,ko01120,ko01200,map00190,map00680,map01100,map01120,map01200	M00144,M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944,R11945	RC00011,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fer4,NAD_binding_8,Pyr_redox_2,Response_reg
YHH1_k127_3414797_0	243164.DET0729	5.347e-264	828.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi,34D48@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
YHH1_k127_3414797_8	880072.Desac_0167	3.09e-46	187.0	COG3383@1|root,COG3383@2|Bacteria,1RAIK@1224|Proteobacteria,42SGD@68525|delta/epsilon subdivisions,2WP4S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4,Fer4_7
YHH1_k127_3414797_2	1379698.RBG1_1C00001G0050	1.734e-139	463.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
YHH1_k127_3414797_6	429009.Adeg_1784	1.223e-59	209.0	COG1894@1|root,COG1908@1|root,COG1894@2|Bacteria,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
YHH1_k127_3414797_3	1379698.RBG1_1C00001G0048	1.215e-125	409.0	COG1941@1|root,COG1941@2|Bacteria,2NQP6@2323|unclassified Bacteria	2|Bacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_lg_C,Fer4,FlpD,Oxidored_q6
YHH1_k127_3414797_1	1379698.RBG1_1C00001G0047	4.037e-210	663.0	COG3259@1|root,COG3259@2|Bacteria,2NQGS@2323|unclassified Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
YHH1_k127_3414797_10	909663.KI867150_gene2060	1.256e-15	83.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WP4D@28221|Deltaproteobacteria,2MQQW@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Hydrogenase maturation protease	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
YHH1_k127_3414797_11	234267.Acid_1154	2.664e-11	64.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YHH1_k127_3436028_0	1329516.JPST01000012_gene181	1.015e-94	319.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,4HAVY@91061|Bacilli,27BE0@186824|Thermoactinomycetaceae	91061|Bacilli	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
YHH1_k127_3436028_2	1499967.BAYZ01000182_gene4418	1.167e-10	68.0	COG2980@1|root,COG2980@2|Bacteria,2NQ1I@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
YHH1_k127_3436028_1	1379698.RBG1_1C00001G0331	5.052e-52	193.0	COG2067@1|root,COG2067@2|Bacteria,2NPV7@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
YHH1_k127_3444205_2	404380.Gbem_2872	3.042e-19	96.0	2DQIT@1|root,33749@2|Bacteria,1N9CN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
YHH1_k127_3444205_1	309799.DICTH_1352	8.588e-35	139.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
YHH1_k127_3444205_0	1379698.RBG1_1C00001G1886	8.255e-79	273.0	COG1058@1|root,COG1058@2|Bacteria,2NP0G@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
YHH1_k127_3445533_0	1122947.FR7_2760	3.521e-34	138.0	29XA7@1|root,30IZT@2|Bacteria,1W1FQ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3445533_2	1267535.KB906767_gene1535	6.948e-23	115.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
YHH1_k127_3445533_1	1121930.AQXG01000004_gene2828	6.536e-24	119.0	COG2911@1|root,COG2911@2|Bacteria,4PPNA@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3533663_3	266117.Rxyl_2891	3.68e-91	312.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4CPCU@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
YHH1_k127_3533663_6	42256.RradSPS_2310	4.144e-58	216.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	menC	GO:0008150,GO:0040007	4.2.1.113,5.1.1.20,5.1.1.3	ko:K01776,ko:K02549,ko:K19802	ko00130,ko00471,ko01100,ko01110,map00130,map00471,map01100,map01110	M00116	R00260,R04031,R10938	RC00302,RC01053,RC03309	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	iNJ661.Rv0553,iSB619.SA_RS09080	MR_MLE_C
YHH1_k127_3533663_4	518766.Rmar_0586	1.888e-82	284.0	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,1FIUJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
YHH1_k127_3533663_0	290318.Cvib_0394	9.765e-155	490.0	COG0447@1|root,COG0447@2|Bacteria,1FDH0@1090|Chlorobi	1090|Chlorobi	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YHH1_k127_3533663_5	1173027.Mic7113_6109	1.804e-68	241.0	COG0596@1|root,COG0596@2|Bacteria,1GQ5T@1117|Cyanobacteria,1H97N@1150|Oscillatoriales	1117|Cyanobacteria	S	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
YHH1_k127_3533663_1	266117.Rxyl_2896	4.484e-151	497.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4CPYA@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
YHH1_k127_3533663_2	266117.Rxyl_2897	8.281e-93	321.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4CQEB@84995|Rubrobacteria	84995|Rubrobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
YHH1_k127_3535921_0	1348635.BBJY01000001_gene2700	1.654e-07	61.0	2DIBC@1|root,302MM@2|Bacteria,1Q9A3@1224|Proteobacteria,1SW1G@1236|Gammaproteobacteria,1Y1YR@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3613249_6	880073.Calab_2217	1.818e-30	125.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
YHH1_k127_3613249_1	880073.Calab_3298	1.475e-64	250.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	ebh	-	-	-	-	-	-	-	-	-	-	-	DUF1611,Inhibitor_I9,Peptidase_S8,SLH
YHH1_k127_3613249_0	945713.IALB_2583	1.521e-106	379.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_3613249_5	443143.GM18_2643	5.675e-34	143.0	COG2984@1|root,COG2984@2|Bacteria,1Q1HH@1224|Proteobacteria,42UE1@68525|delta/epsilon subdivisions,2WR33@28221|Deltaproteobacteria,43VBE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
YHH1_k127_3613249_2	290397.Adeh_2011	1.724e-62	235.0	COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria,2Z0GM@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
YHH1_k127_3613249_7	330214.NIDE0779	3.341e-21	97.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_3613249_9	448385.sce2546	2.113e-12	72.0	COG2203@1|root,COG2204@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2YUZY@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HD,Response_reg
YHH1_k127_3613249_4	926569.ANT_11740	2.294e-50	199.0	COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G6UY@200795|Chloroflexi	200795|Chloroflexi	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
YHH1_k127_3613249_3	1379698.RBG1_1C00001G0135	5.183e-59	212.0	COG0461@1|root,COG0461@2|Bacteria,2NPFJ@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YHH1_k127_3613249_8	28258.KP05_02470	6.061e-18	88.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,1XKU7@135619|Oceanospirillales	135619|Oceanospirillales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
YHH1_k127_3621508_1	246197.MXAN_1696	1.301e-53	207.0	COG0823@1|root,COG3291@1|root,COG5492@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
YHH1_k127_3621508_0	580332.Slit_2212	1.639e-72	263.0	COG0457@1|root,COG0457@2|Bacteria,1P464@1224|Proteobacteria,2VMYZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF560)	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_19
YHH1_k127_3624004_2	656519.Halsa_1954	1.22e-11	66.0	COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia,3WBQP@53433|Halanaerobiales	186801|Clostridia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YHH1_k127_3624004_0	1121405.dsmv_3065	1.474e-95	322.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria,2MITD@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
YHH1_k127_3624004_1	1379698.RBG1_1C00001G1432	7.355e-85	306.0	COG1196@1|root,COG1196@2|Bacteria,2NNYZ@2323|unclassified Bacteria	2|Bacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529,ko:K19171	-	-	-	-	ko00000,ko02048,ko03036	-	-	-	SMC_N,SMC_hinge
YHH1_k127_3631065_1	927658.AJUM01000022_gene1089	6.232e-61	211.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,2FX41@200643|Bacteroidia	976|Bacteroidetes	P	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
YHH1_k127_3631065_0	927658.AJUM01000022_gene1090	1.622e-224	710.0	COG0471@1|root,COG0471@2|Bacteria,4NF52@976|Bacteroidetes,2FNWH@200643|Bacteroidia,3XK7J@558415|Marinilabiliaceae	976|Bacteroidetes	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
YHH1_k127_3666405_4	420662.Mpe_B0190	5.084e-06	54.0	2D113@1|root,32T9N@2|Bacteria,1N3N7@1224|Proteobacteria,2VTZS@28216|Betaproteobacteria,1KP0E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3666405_2	1121396.KB892990_gene4486	1.864e-18	92.0	2E0F6@1|root,32W1G@2|Bacteria,1N6I3@1224|Proteobacteria,42V01@68525|delta/epsilon subdivisions,2WQWS@28221|Deltaproteobacteria,2MMAB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3666405_0	483219.LILAB_25975	9.854e-41	168.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42MF0@68525|delta/epsilon subdivisions,2WMC1@28221|Deltaproteobacteria,2Z334@29|Myxococcales	28221|Deltaproteobacteria	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH1_k127_3666405_1	1458357.BG58_06830	4.967e-29	132.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2VMBN@28216|Betaproteobacteria,1K27P@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
YHH1_k127_3666405_3	324925.Ppha_0350	2.685e-10	64.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH1_k127_3678974_3	926550.CLDAP_06530	1.235e-51	190.0	COG0006@1|root,COG0006@2|Bacteria,2G5J8@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
YHH1_k127_3678974_0	926569.ANT_13970	1.534e-78	271.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YHH1_k127_3678974_1	1218076.BAYB01000025_gene4354	3.126e-59	213.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VRU7@28216|Betaproteobacteria,1K36H@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	-	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
YHH1_k127_3678974_2	926569.ANT_17680	5.392e-54	198.0	COG2047@1|root,COG2047@2|Bacteria	2|Bacteria	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
YHH1_k127_3692040_0	266117.Rxyl_0946	8.905e-96	324.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4CP7R@84995|Rubrobacteria	201174|Actinobacteria	P	PFAM ABC transporter related	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
YHH1_k127_3692040_1	530564.Psta_2541	2.701e-77	269.0	COG1879@1|root,COG1879@2|Bacteria,2IYMH@203682|Planctomycetes	203682|Planctomycetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
YHH1_k127_3692040_2	1487923.DP73_00875	1.503e-66	260.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,2646G@186807|Peptococcaceae	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_3692040_3	1476876.JOJO01000039_gene5905	1.155e-06	57.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
YHH1_k127_3698656_2	1123054.KB907702_gene1604	5.518e-12	72.0	2FJ2N@1|root,34ASZ@2|Bacteria,1P31M@1224|Proteobacteria,1SRU1@1236|Gammaproteobacteria,1X194@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3698656_0	323261.Noc_2913	5.179e-135	436.0	COG5653@1|root,COG5653@2|Bacteria,1RAB9@1224|Proteobacteria,1SKTJ@1236|Gammaproteobacteria,1X07E@135613|Chromatiales	135613|Chromatiales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
YHH1_k127_3698656_1	1266925.JHVX01000005_gene1899	8.327e-81	273.0	COG0726@1|root,COG0726@2|Bacteria,1RDB8@1224|Proteobacteria,2VY2J@28216|Betaproteobacteria,372Q3@32003|Nitrosomonadales	28216|Betaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3722725_3	706587.Desti_1549	3.489e-51	187.0	COG1024@1|root,COG1024@2|Bacteria,1N2V7@1224|Proteobacteria,42UXR@68525|delta/epsilon subdivisions,2WQCT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YHH1_k127_3722725_1	450851.PHZ_c2816	2.911e-112	367.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,2KG46@204458|Caulobacterales	204458|Caulobacterales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH1_k127_3722725_2	1366050.N234_12310	6.777e-53	197.0	COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,2WH24@28216|Betaproteobacteria,1K5AI@119060|Burkholderiaceae	28216|Betaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
YHH1_k127_3722725_7	1223410.KN050846_gene441	1.395e-06	58.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia	976|Bacteroidetes	M	Opacity protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
YHH1_k127_3722725_0	1379698.RBG1_1C00001G0607	7.26e-117	407.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
YHH1_k127_3722725_4	945713.IALB_0238	2.973e-37	148.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
YHH1_k127_3722725_5	926564.KI911760_gene4963	1.972e-31	126.0	2C3CF@1|root,32RRR@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3175
YHH1_k127_3722725_6	616991.JPOO01000001_gene4165	1.295e-15	78.0	2AFVV@1|root,315YK@2|Bacteria,4NQ4S@976|Bacteroidetes,1I2VI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_37300_8	686340.Metal_3843	3.855e-23	104.0	COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,1T460@1236|Gammaproteobacteria,1XEF0@135618|Methylococcales	135618|Methylococcales	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_37300_1	1379698.RBG1_1C00001G1494	1.649e-145	473.0	COG0044@1|root,COG0044@2|Bacteria,2NNWP@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
YHH1_k127_37300_2	1379698.RBG1_1C00001G1495	1.485e-136	440.0	COG0540@1|root,COG0540@2|Bacteria,2NNPZ@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15490	OTCace,OTCace_N
YHH1_k127_37300_6	1379698.RBG1_1C00001G1496	3.897e-62	222.0	COG2065@1|root,COG2065@2|Bacteria,2NPF2@2323|unclassified Bacteria	2|Bacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
YHH1_k127_37300_9	1382356.JQMP01000001_gene991	4.767e-12	77.0	COG0823@1|root,COG0823@2|Bacteria,2G8Z9@200795|Chloroflexi,27XTF@189775|Thermomicrobia	189775|Thermomicrobia	U	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
YHH1_k127_37300_0	665571.STHERM_c16630	0.0	1582.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,2J5QV@203691|Spirochaetes	203691|Spirochaetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH1_k127_37300_4	1382359.JIAL01000001_gene721	3.055e-71	245.0	COG0717@1|root,COG0717@2|Bacteria,3Y42N@57723|Acidobacteria,2JIA0@204432|Acidobacteriia	204432|Acidobacteriia	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
YHH1_k127_37300_7	316067.Geob_2631	2.184e-24	107.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SPF@68525|delta/epsilon subdivisions,2WPVC@28221|Deltaproteobacteria,43UWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH1_k127_37300_5	1379698.RBG1_1C00001G1085	6.06e-64	223.0	COG2109@1|root,COG2109@2|Bacteria,2NPNR@2323|unclassified Bacteria	2|Bacteria	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
YHH1_k127_37300_3	273068.TTE2220	3.378e-101	338.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,42EKM@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YHH1_k127_37300_10	1291050.JAGE01000001_gene3033	1.818e-05	54.0	2EC4I@1|root,3363E@2|Bacteria,1VJH4@1239|Firmicutes,25E22@186801|Clostridia	186801|Clostridia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
YHH1_k127_3748802_1	314230.DSM3645_10782	4.728e-19	95.0	COG1943@1|root,COG1943@2|Bacteria,2IZK4@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_3748802_0	1340493.JNIF01000003_gene4212	2.16e-30	123.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_3753972_0	880073.Calab_3325	1.095e-09	66.0	28ZRK@1|root,2ZMGF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3753972_2	5334.XP_003035043.1	0.0002378	45.0	COG0366@1|root,KOG0471@2759|Eukaryota,38EYC@33154|Opisthokonta,3NYFV@4751|Fungi,3UXW2@5204|Basidiomycota,2273H@155619|Agaricomycetes,3W9XU@5338|Agaricales	4751|Fungi	G	Domain of unknown function (DUF1966)	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF1966
YHH1_k127_3753972_1	1123368.AUIS01000006_gene552	3.439e-07	52.0	COG0732@1|root,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	hsdS	-	2.1.1.72,3.1.21.3	ko:K01154,ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
YHH1_k127_3799548_1	1379698.RBG1_1C00001G0639	4.576e-28	117.0	COG2088@1|root,COG2088@2|Bacteria,2NQ05@2323|unclassified Bacteria	2|Bacteria	D	SpoVG	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
YHH1_k127_3799548_0	251229.Chro_2730	1.457e-86	295.0	COG1503@1|root,COG1503@2|Bacteria,1G29A@1117|Cyanobacteria,3VMJ4@52604|Pleurocapsales	1117|Cyanobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3801063_1	1379698.RBG1_1C00001G0961	1.237e-116	382.0	COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
YHH1_k127_3801063_5	1232410.KI421413_gene502	3.189e-50	190.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,43TES@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	integrase domain protein SAM domain protein	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH1_k127_3801063_4	373903.Hore_07560	1.041e-65	229.0	COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,24FS4@186801|Clostridia,3WAJD@53433|Halanaerobiales	186801|Clostridia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
YHH1_k127_3801063_0	518766.Rmar_1879	1.274e-171	549.0	COG1220@1|root,COG1220@2|Bacteria,4NFI2@976|Bacteroidetes,1FIQI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
YHH1_k127_3801063_3	266117.Rxyl_1327	1.701e-69	241.0	COG2514@1|root,COG2514@2|Bacteria,2HNS6@201174|Actinobacteria,4CPZV@84995|Rubrobacteria	84995|Rubrobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
YHH1_k127_3801063_7	1380408.AVGH01000050_gene1316	2.224e-05	55.0	COG4758@1|root,COG4758@2|Bacteria,1V3D0@1239|Firmicutes,4HDIA@91061|Bacilli,21VQ2@150247|Anoxybacillus	91061|Bacilli	S	Cell wall-active antibiotics response 4TMS YvqF	yvqF	-	-	ko:K11622	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2154
YHH1_k127_3801063_6	946077.W5A_02335	3.856e-11	75.0	COG3203@1|root,COG3203@2|Bacteria,4NDYW@976|Bacteroidetes,1HWYP@117743|Flavobacteriia	976|Bacteroidetes	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
YHH1_k127_3801063_2	1379698.RBG1_1C00001G0963	1.956e-100	335.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YHH1_k127_3843391_0	580331.Thit_0404	3.617e-83	292.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,24A6D@186801|Clostridia,42J4J@68295|Thermoanaerobacterales	186801|Clostridia	C	Best Blastp hit gi 7462068 pir H72266 astB chuR-related protein - Thermotoga maritima (strain MSB8) gi 4981883 gb AAD36396.1 AE001787_1 (AE001787) astB chuR-related protein Thermotoga maritima , score	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
YHH1_k127_3851260_1	909663.KI867151_gene2966	1.986e-178	569.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1NT36@1224|Proteobacteria,42ZEC@68525|delta/epsilon subdivisions,2WU3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
YHH1_k127_3851260_0	909663.KI867151_gene2965	1.106e-262	820.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MR61@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, NADH-binding	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
YHH1_k127_3851260_2	909663.KI867151_gene2964	2.661e-57	205.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,43DNM@68525|delta/epsilon subdivisions,2X6M5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
YHH1_k127_3851260_5	909663.KI867151_gene2963	3.505e-09	64.0	COG2204@1|root,COG2204@2|Bacteria,1Q5EK@1224|Proteobacteria,433QZ@68525|delta/epsilon subdivisions,2WXYI@28221|Deltaproteobacteria	2|Bacteria	T	cheY-homologous receiver domain	-	-	2.1.1.80,3.1.1.61,3.1.3.3	ko:K03413,ko:K07315,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03021	-	-	-	HATPase_c,HDOD,HD_5,Response_reg
YHH1_k127_3851260_4	1121106.JQKB01000005_gene2162	4.236e-39	156.0	COG0596@1|root,COG0596@2|Bacteria,1R9VJ@1224|Proteobacteria,2U26I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	MA20_06765	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
YHH1_k127_3851260_3	330214.NIDE1121	3.018e-39	152.0	COG1600@1|root,COG1600@2|Bacteria,3J19A@40117|Nitrospirae	40117|Nitrospirae	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
YHH1_k127_3873079_0	1265505.ATUG01000001_gene4318	2.852e-141	462.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42Q8R@68525|delta/epsilon subdivisions,2WMDK@28221|Deltaproteobacteria,2MJEG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
YHH1_k127_3873079_1	1382356.JQMP01000004_gene492	4.884e-39	153.0	COG1506@1|root,COG1506@2|Bacteria,2G8QF@200795|Chloroflexi,27YT1@189775|Thermomicrobia	189775|Thermomicrobia	E	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
YHH1_k127_3904475_8	827.JFJK01000014_gene596	6.705e-41	154.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,42QUT@68525|delta/epsilon subdivisions,2YNVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
YHH1_k127_3904475_6	518766.Rmar_1352	1.998e-59	210.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
YHH1_k127_3904475_5	1380763.BG53_07580	7.446e-73	256.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,26SEN@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
YHH1_k127_3904475_2	634500.EbC_29260	1.499e-121	396.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,3X4FM@551|Erwinia	1236|Gammaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046872,GO:0071704,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSDY_1059.SDY_2206,iSF_1195.SF2102,iSFxv_1172.SFxv_2338,iS_1188.S2225	NTP_transferase
YHH1_k127_3904475_1	713586.KB900536_gene902	2.817e-137	445.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1WX1W@135613|Chromatiales	135613|Chromatiales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YHH1_k127_3904475_0	1379698.RBG1_1C00001G0844	1.477e-184	588.0	COG0215@1|root,COG0215@2|Bacteria,2NNP0@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c	DALR_2,tRNA-synt_1e,tRNA-synt_1g
YHH1_k127_3904475_3	292459.STH2675	8.953e-113	375.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
YHH1_k127_3904475_7	1379698.RBG1_1C00001G0843	3.883e-42	164.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.1.3.5	ko:K07025,ko:K08723	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH1_k127_3904475_4	1379698.RBG1_1C00001G0842	9.011e-87	297.0	COG1181@1|root,COG1181@2|Bacteria,2NPB2@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
YHH1_k127_3904475_9	1403948.Q618_VCMC00002G0050	9.288e-06	53.0	COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,4D49A@85005|Actinomycetales	201174|Actinobacteria	S	SNARE-like domain protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
YHH1_k127_3909160_5	316067.Geob_1432	1.789e-07	52.0	COG3303@1|root,COG3303@2|Bacteria,1RG2D@1224|Proteobacteria	1224|Proteobacteria	P	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YHH1_k127_3909160_1	1158338.JNLJ01000001_gene945	4.526e-100	338.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,TPR_11
YHH1_k127_3909160_3	1158338.JNLJ01000001_gene942	8.076e-48	183.0	COG0760@1|root,COG0760@2|Bacteria,2G5GE@200783|Aquificae	200783|Aquificae	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3
YHH1_k127_3909160_4	221359.RS9916_39376	5.441e-18	93.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1G193@1117|Cyanobacteria,1H438@1129|Synechococcus	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
YHH1_k127_3909160_0	909663.KI867150_gene389	2.585e-108	355.0	COG1216@1|root,COG1216@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria,2MQ8C@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
YHH1_k127_3909160_2	96561.Dole_1741	1.315e-52	203.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions,2WNS4@28221|Deltaproteobacteria,2MMKQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
YHH1_k127_3916016_2	1304872.JAGC01000005_gene2040	1.737e-39	168.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WJF3@28221|Deltaproteobacteria,2M98U@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
YHH1_k127_3916016_1	1121405.dsmv_1693	5.02e-72	248.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,2MMB5@213118|Desulfobacterales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
YHH1_k127_3916016_0	404589.Anae109_4242	3.148e-125	409.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YYW6@29|Myxococcales	28221|Deltaproteobacteria	K	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat
YHH1_k127_3920205_4	1121918.ARWE01000001_gene3139	1.322e-16	80.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,42P70@68525|delta/epsilon subdivisions,2WJGD@28221|Deltaproteobacteria,43TC0@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
YHH1_k127_3920205_3	443143.GM18_4058	1.006e-30	132.0	2FBQ6@1|root,343V4@2|Bacteria,1P3NP@1224|Proteobacteria,431Y8@68525|delta/epsilon subdivisions,2WX21@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3261
YHH1_k127_3920205_5	1121918.ARWE01000001_gene3137	2.322e-15	80.0	COG0764@1|root,COG0764@2|Bacteria,1QZ5Z@1224|Proteobacteria,43CGT@68525|delta/epsilon subdivisions,2X7RZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3920205_1	1121918.ARWE01000001_gene3136	3.06e-62	218.0	COG0824@1|root,COG0824@2|Bacteria,1RH6W@1224|Proteobacteria,42U0Z@68525|delta/epsilon subdivisions,2WQ4D@28221|Deltaproteobacteria,43UYB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
YHH1_k127_3920205_0	443143.GM18_4055	8.648e-119	393.0	COG0304@1|root,COG0304@2|Bacteria,1RAFK@1224|Proteobacteria,42R69@68525|delta/epsilon subdivisions,2WMWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH1_k127_3920205_2	1121918.ARWE01000001_gene3134	2.101e-48	179.0	COG0304@1|root,COG0304@2|Bacteria,1R0WN@1224|Proteobacteria,43D2H@68525|delta/epsilon subdivisions,2X89P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ketoacyl-synt
YHH1_k127_3950029_0	1379698.RBG1_1C00001G0304	4.67e-91	306.0	COG0413@1|root,COG0413@2|Bacteria,2NP1G@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
YHH1_k127_3950029_1	880073.Calab_2860	7.285e-62	218.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
YHH1_k127_3966546_1	1191523.MROS_2693	1.26e-255	797.0	COG0459@1|root,COG0459@2|Bacteria	2|Bacteria	O	protein refolding	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YHH1_k127_3966546_3	1379698.RBG1_1C00001G0288	1.696e-41	154.0	COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YHH1_k127_3966546_2	1121930.AQXG01000001_gene1272	5.213e-92	314.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IQN0@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
YHH1_k127_3966546_0	755732.Fluta_0362	0.0	1283.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2PAGA@246874|Cryomorphaceae	976|Bacteroidetes	V	TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YHH1_k127_3966546_4	1395513.P343_00530	1.523e-11	70.0	COG0454@1|root,COG0456@2|Bacteria,1V4GU@1239|Firmicutes,4HKA1@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH1_k127_4004254_2	880073.Calab_1920	4.654e-51	186.0	COG1801@1|root,COG1801@2|Bacteria,2NPDU@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YHH1_k127_4004254_0	1047013.AQSP01000052_gene2600	6.478e-91	309.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YHH1_k127_4004254_1	1047013.AQSP01000052_gene2599	1.257e-57	218.0	COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH1_k127_4004254_3	1051985.l11_22260	1.063e-42	169.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,2KPUP@206351|Neisseriales	206351|Neisseriales	M	Belongs to the peptidase S11 family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
YHH1_k127_4004254_4	1173020.Cha6605_3993	0.0006003	48.0	COG5113@1|root,COG3236@2|Bacteria,1G60B@1117|Cyanobacteria	1117|Cyanobacteria	O	protein, ribA ribD-fused	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
YHH1_k127_4022723_3	349161.Dred_2964	1.676e-26	114.0	COG1959@1|root,COG1959@2|Bacteria,1VA5B@1239|Firmicutes,24JMN@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH1_k127_4022723_0	1379698.RBG1_1C00001G1877	3.933e-119	389.0	COG0214@1|root,COG0214@2|Bacteria,2NNZ6@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
YHH1_k127_4022723_1	1521187.JPIM01000022_gene637	3.05e-99	331.0	COG4422@1|root,COG4422@2|Bacteria,2G7TP@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
YHH1_k127_4022723_2	317936.Nos7107_4189	8.88e-39	153.0	COG4826@1|root,COG4826@2|Bacteria,1G29E@1117|Cyanobacteria,1HIIV@1161|Nostocales	1117|Cyanobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
YHH1_k127_4043172_2	1379698.RBG1_1C00001G1046	3.268e-71	252.0	COG1940@1|root,COG1940@2|Bacteria,2NPRP@2323|unclassified Bacteria	2|Bacteria	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH1_k127_4043172_1	483219.LILAB_07675	3.779e-109	366.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MCR@68525|delta/epsilon subdivisions,2WJXI@28221|Deltaproteobacteria,2YY6G@29|Myxococcales	28221|Deltaproteobacteria	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	lysN	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
YHH1_k127_4043172_5	1392502.JNIO01000008_gene1840	1.266e-52	196.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4H2QR@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
YHH1_k127_4043172_0	574087.Acear_1870	4.065e-135	450.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3WBGE@53433|Halanaerobiales	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
YHH1_k127_4043172_3	1120999.JONM01000008_gene1930	2.614e-68	237.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,2KQ6H@206351|Neisseriales	206351|Neisseriales	EH	Glutamine amidotransferase, class I	pabA	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YHH1_k127_4043172_4	867903.ThesuDRAFT_01414	3.667e-64	224.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3WCZN@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
YHH1_k127_4052970_1	1379698.RBG1_1C00001G1724	4.256e-127	415.0	COG0845@1|root,COG0845@2|Bacteria,2NR7K@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
YHH1_k127_4052970_0	1379698.RBG1_1C00001G1725	0.0	1209.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
YHH1_k127_406907_6	395494.Galf_1373	4.28e-16	80.0	2EIC1@1|root,33C3D@2|Bacteria,1NHMH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
YHH1_k127_406907_4	1198452.Jab_1c19600	6.154e-33	129.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,474TX@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	'Cold-shock' DNA-binding domain	cspD2	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
YHH1_k127_406907_3	1123393.KB891316_gene1605	8.516e-42	158.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria,1KT32@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
YHH1_k127_406907_5	243231.GSU0710	1.305e-29	123.0	2BW01@1|root,32RUH@2|Bacteria,1N665@1224|Proteobacteria,431EY@68525|delta/epsilon subdivisions,2WWFV@28221|Deltaproteobacteria,43VKI@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_406907_0	261292.Nit79A3_1538	1.374e-267	832.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,372Q8@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YHH1_k127_406907_2	395494.Galf_0044	3.109e-74	253.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2VRQB@28216|Betaproteobacteria,44WFC@713636|Nitrosomonadales	28216|Betaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_406907_1	1266925.JHVX01000002_gene1083	2.008e-78	269.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,3720B@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH1_k127_4087623_2	452637.Oter_4607	9.851e-49	179.0	COG3005@1|root,COG3005@2|Bacteria,46T0N@74201|Verrucomicrobia,3K8D9@414999|Opitutae	414999|Opitutae	C	TIGRFAM cytochrome c nitrate reductase, small subunit	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
YHH1_k127_4087623_1	266117.Rxyl_0103	1.211e-50	196.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GK25@201174|Actinobacteria,4CQ6R@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM ATP-binding region, ATPase-like histidine kinase A-like	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA
YHH1_k127_4087623_0	386456.JQKN01000001_gene2206	2.141e-56	205.0	COG2201@1|root,arCOG04921@2157|Archaea,2Y7RM@28890|Euryarchaeota	28890|Euryarchaeota	N	MCP methyltransferase, CheR-type	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS,PAS_10,PAS_4,PAS_9
YHH1_k127_4095625_6	482537.XP_008567975.1	1.333e-09	64.0	COG0666@1|root,KOG0504@2759|Eukaryota,39SVQ@33154|Opisthokonta,3BCY7@33208|Metazoa,3CWQE@33213|Bilateria,480HT@7711|Chordata,492S2@7742|Vertebrata,3J46R@40674|Mammalia,35ENW@314146|Euarchontoglires	33208|Metazoa	V	ankyrin repeat domain-containing protein	ANKRD26	-	-	ko:K17299	-	-	-	-	ko00000,ko04147	-	-	-	Ank_2,Ank_4,CCDC144C,DUF3496
YHH1_k127_4095625_7	1168289.AJKI01000044_gene44	2.883e-08	59.0	COG0823@1|root,COG0823@2|Bacteria,4P0F7@976|Bacteroidetes,2G0E1@200643|Bacteroidia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PD40,TPR_19
YHH1_k127_4095625_0	1047013.AQSP01000093_gene11	6.942e-180	576.0	COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YHH1_k127_4095625_1	1047013.AQSP01000077_gene2274	7.148e-168	542.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8,Fer4_9
YHH1_k127_4095625_5	1047013.AQSP01000093_gene13	1.001e-31	133.0	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
YHH1_k127_4095625_4	1047013.AQSP01000093_gene14	2.931e-45	166.0	COG2920@1|root,COG2920@2|Bacteria,2NQ6I@2323|unclassified Bacteria	2|Bacteria	P	DsrC like protein	dsrC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
YHH1_k127_4095625_9	504472.Slin_4641	2.076e-07	56.0	COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH1_k127_4095625_8	1047013.AQSP01000051_gene2576	3.81e-08	61.0	COG2220@1|root,COG2220@2|Bacteria,2NRBH@2323|unclassified Bacteria	2|Bacteria	S	Beta-lactamase superfamily domain	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
YHH1_k127_4095625_3	706587.Desti_1825	1.068e-57	215.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2WJQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
YHH1_k127_4095625_2	1047013.AQSP01000115_gene352	1.402e-68	240.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4100916_0	1167006.UWK_01068	2.054e-318	994.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,2MIUG@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH1_k127_4102207_6	1379698.RBG1_1C00001G1104	8.361e-12	75.0	2B0A3@1|root,31SM2@2|Bacteria,2NRWJ@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YHH1_k127_4102207_8	1379698.RBG1_1C00001G1104	2.974e-06	56.0	2B0A3@1|root,31SM2@2|Bacteria,2NRWJ@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YHH1_k127_4102207_9	316067.Geob_1620	4.456e-05	48.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K16191,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.6.1.3	-	-	Big_3_2,Calx-beta,OmpA
YHH1_k127_4102207_7	1089547.KB913013_gene4143	7.315e-07	59.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,47R1B@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YHH1_k127_4102207_1	1267535.KB906767_gene1462	2.325e-68	246.0	COG1131@1|root,COG1131@2|Bacteria,3Y7J3@57723|Acidobacteria,2JMS8@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_4102207_4	1267535.KB906767_gene1461	2.841e-18	95.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_4
YHH1_k127_4102207_5	880073.Calab_1548	4.927e-16	84.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YHH1_k127_4102207_0	1048983.EL17_19945	6.692e-140	458.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,47JN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YHH1_k127_4102207_2	861299.J421_6340	1.193e-63	227.0	COG1028@1|root,COG1028@2|Bacteria,1ZTIT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH1_k127_4102207_3	387631.Asulf_00716	8.95e-37	151.0	COG0697@1|root,arCOG00271@2157|Archaea,2XXKE@28890|Euryarchaeota,2466R@183980|Archaeoglobi	183980|Archaeoglobi	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_4117852_2	1121904.ARBP01000046_gene1866	2.717e-12	78.0	2EFDX@1|root,3396Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4117852_0	1121422.AUMW01000003_gene848	2.703e-88	301.0	COG0074@1|root,COG0074@2|Bacteria,1TPIT@1239|Firmicutes,249MP@186801|Clostridia,260KG@186807|Peptococcaceae	186801|Clostridia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
YHH1_k127_4117852_1	633148.Tagg_1018	3.17e-60	219.0	COG0045@1|root,arCOG01337@2157|Archaea,2XPUW@28889|Crenarchaeota	28889|Crenarchaeota	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
YHH1_k127_4120820_0	926560.KE387027_gene261	1.72e-117	429.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,1WMF2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
YHH1_k127_4147805_0	984262.SGRA_3548	4.982e-65	229.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes,1INQ4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_4147805_1	1122605.KB893626_gene2743	1.659e-43	171.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YHH1_k127_4147805_2	204669.Acid345_0556	1.142e-16	83.0	COG0816@1|root,COG0816@2|Bacteria,3Y59A@57723|Acidobacteria,2JP2U@204432|Acidobacteriia	204432|Acidobacteriia	J	Likely ribonuclease with RNase H fold.	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
YHH1_k127_4151277_2	396588.Tgr7_2398	4.596e-08	56.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	neuA	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,Lipase_GDSL_2
YHH1_k127_4151277_0	227377.CBU_0580	1.609e-52	196.0	COG3394@1|root,COG3394@2|Bacteria,1MX3P@1224|Proteobacteria,1RRC4@1236|Gammaproteobacteria,1JDJV@118969|Legionellales	118969|Legionellales	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
YHH1_k127_4151277_1	227377.CBU_0578	4.875e-38	145.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1JGP1@118969|Legionellales	118969|Legionellales	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
YHH1_k127_4193741_2	1379698.RBG1_1C00001G1510	1.81e-41	155.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YHH1_k127_4193741_1	1121918.ARWE01000001_gene1797	1.543e-50	206.0	COG1404@1|root,COG1404@2|Bacteria,1QYWU@1224|Proteobacteria,42VXP@68525|delta/epsilon subdivisions,2X7PK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4193741_0	926550.CLDAP_04870	2.867e-116	408.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YHH1_k127_4193741_3	316274.Haur_4151	7.411e-06	49.0	COG0697@1|root,COG0697@2|Bacteria,2G6XF@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_4212649_0	1296416.JACB01000016_gene4458	1.987e-112	393.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia,2YIQF@290174|Aquimarina	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_4215668_0	1183438.GKIL_1369	1.027e-83	293.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
YHH1_k127_4215668_1	1313304.CALK_1985	4.785e-77	275.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YHH1_k127_4215668_2	1047013.AQSP01000130_gene1863	2.928e-42	160.0	28KQH@1|root,2ZA8A@2|Bacteria	2|Bacteria	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
YHH1_k127_4239079_5	439235.Dalk_1526	8.872e-24	107.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
YHH1_k127_4239079_4	237368.SCABRO_04028	7.517e-33	134.0	COG0644@1|root,COG0664@1|root,COG0644@2|Bacteria,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	prnA	-	1.14.19.9	ko:K07058,ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_5,Trp_halogenase,cNMP_binding
YHH1_k127_4239079_1	1168034.FH5T_19015	6.089e-109	368.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4239079_2	1049564.TevJSym_ad00590	6.559e-55	198.0	COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,1RPV0@1236|Gammaproteobacteria,1J68H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	MarC family integral membrane protein	yhgN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
YHH1_k127_4239079_6	1267535.KB906767_gene1545	2.66e-15	79.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_4239079_0	1403819.BATR01000093_gene2905	3.382e-114	377.0	COG3239@1|root,COG3239@2|Bacteria,46SX7@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Fatty acid desaturase	desA	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
YHH1_k127_424016_2	1121920.AUAU01000007_gene487	7.767e-80	272.0	COG0436@1|root,COG0436@2|Bacteria,3Y2IZ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH1_k127_424016_10	880073.Calab_0696	1.876e-26	126.0	COG1262@1|root,COG2911@1|root,COG3055@1|root,COG3934@1|root,COG5492@1|root,COG1262@2|Bacteria,COG2911@2|Bacteria,COG3055@2|Bacteria,COG3934@2|Bacteria,COG5492@2|Bacteria,2NPU7@2323|unclassified Bacteria	2|Bacteria	G	Sulfatase-modifying factor enzyme 1	-	-	3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89	ko:K01176,ko:K01206,ko:K01218,ko:K01219,ko:K01224	ko00051,ko00500,ko00511,ko01100,ko02024,ko04973,map00051,map00500,map00511,map01100,map02024,map04973	-	R01332,R02108,R02112,R11262	RC00467	ko00000,ko00001,ko01000,ko04147	-	GH13,GH26,GH29	-	Big_2,DctA-YdbH,FGE-sulfatase
YHH1_k127_424016_7	472759.Nhal_3039	2.412e-36	144.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,1SCEH@1236|Gammaproteobacteria,1WZAH@135613|Chromatiales	135613|Chromatiales	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
YHH1_k127_424016_3	697281.Mahau_0729	3.376e-66	239.0	COG0454@1|root,COG0456@2|Bacteria,1V40T@1239|Firmicutes,250X6@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_424016_1	118168.MC7420_848	6.035e-130	424.0	COG1052@1|root,COG1052@2|Bacteria,1G028@1117|Cyanobacteria,1H7XD@1150|Oscillatoriales	1117|Cyanobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH1_k127_424016_0	1379698.RBG1_1C00001G1860	3.088e-169	537.0	COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria	2|Bacteria	D	MreB/Mbl protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH1_k127_424016_8	1007096.BAGW01000030_gene9	8.147e-29	124.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,2N772@216572|Oscillospiraceae	186801|Clostridia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_424016_11	1379698.RBG1_1C00001G1864	0.0006036	50.0	2DGXT@1|root,2ZXPG@2|Bacteria,2NRPI@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_424016_4	1125863.JAFN01000001_gene3569	9.622e-50	189.0	2DREW@1|root,33BF6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_424016_6	1379698.RBG1_1C00001G1098	5.916e-45	166.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
YHH1_k127_424016_9	1379698.RBG1_1C00001G0890	1.249e-28	119.0	COG0745@1|root,COG0745@2|Bacteria	1379698.RBG1_1C00001G0890|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_424016_5	880073.Calab_1982	5.491e-45	170.0	COG0691@1|root,COG0691@2|Bacteria,2NPFK@2323|unclassified Bacteria	2|Bacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YHH1_k127_4245769_8	1336241.JAEB01000005_gene1364	1.23e-05	52.0	2ECCZ@1|root,336B8@2|Bacteria,1VGWG@1239|Firmicutes,24PAF@186801|Clostridia,25XQ1@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4245769_2	65093.PCC7418_0110	2.437e-145	473.0	COG2081@1|root,COG2081@2|Bacteria,1FZZ1@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM flavoprotein, HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
YHH1_k127_4245769_0	1379698.RBG1_1C00001G0414	0.0	1016.0	COG0525@1|root,COG0525@2|Bacteria,2NNKR@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iLJ478.TM1817	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
YHH1_k127_4245769_3	648996.Theam_1519	1.42e-72	253.0	COG1694@1|root,COG3956@2|Bacteria,2G3T8@200783|Aquificae	200783|Aquificae	S	TIGRFAM MazG family protein	mazG	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG
YHH1_k127_4245769_5	880073.Calab_0119	3.888e-14	84.0	2F9BU@1|root,341NU@2|Bacteria,2NR9C@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4245769_1	472759.Nhal_2871	1.916e-166	529.0	COG0823@1|root,COG0823@2|Bacteria,1QW3I@1224|Proteobacteria,1SYTE@1236|Gammaproteobacteria,1X0JZ@135613|Chromatiales	135613|Chromatiales	U	beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH1_k127_4245769_4	1379698.RBG1_1C00001G0990	1.735e-52	201.0	COG3359@1|root,COG3359@2|Bacteria,2NPCP@2323|unclassified Bacteria	2|Bacteria	L	RNase_H superfamily	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
YHH1_k127_4279018_1	1379698.RBG1_1C00001G1654	1.482e-72	247.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH1_k127_4279018_0	1379698.RBG1_1C00001G0356	1.531e-117	400.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
YHH1_k127_4279423_1	383372.Rcas_0827	3.887e-37	145.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	yueE	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	Guanylate_cyc,HD
YHH1_k127_4279423_0	261292.Nit79A3_0232	3.369e-217	705.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,1RJUD@1224|Proteobacteria,2WBAA@28216|Betaproteobacteria,372PS@32003|Nitrosomonadales	28216|Betaproteobacteria	PT	TonB-dependent receptor, beta-barrel	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TonB_dep_Rec
YHH1_k127_4297957_1	1379698.RBG1_1C00001G0222	4.589e-130	432.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
YHH1_k127_4297957_0	1499967.BAYZ01000139_gene157	1.364e-266	842.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH1_k127_4297957_2	478749.BRYFOR_07906	4.252e-71	252.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YHH1_k127_4307363_5	247490.KSU1_C0709	3.791e-29	123.0	COG1633@1|root,COG1633@2|Bacteria,2J3M5@203682|Planctomycetes	203682|Planctomycetes	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YHH1_k127_4307363_4	1279009.ADICEAN_04042	4.827e-42	164.0	COG3685@1|root,COG3685@2|Bacteria,4NMCT@976|Bacteroidetes,47QDP@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
YHH1_k127_4307363_1	1121121.KB894286_gene2494	8.64e-61	218.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,26QZR@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH1_k127_4307363_3	1191523.MROS_2552	3.828e-45	173.0	COG1386@1|root,COG1386@2|Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
YHH1_k127_4307363_2	1379698.RBG1_1C00001G1229	9.814e-54	199.0	COG1354@1|root,COG1354@2|Bacteria,2NPM8@2323|unclassified Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
YHH1_k127_4307363_0	1379698.RBG1_1C00001G1230	9.375e-64	225.0	COG0180@1|root,COG0180@2|Bacteria,2NNQX@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class I (W and Y)	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH1_k127_4307925_0	533240.CRC_01133	1.418e-48	175.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding,Thioesterase
YHH1_k127_4307925_1	371731.Rsw2DRAFT_3037	6.527e-05	54.0	2EXPU@1|root,33QZD@2|Bacteria,1NTAS@1224|Proteobacteria,2UPQZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4328184_3	1379698.RBG1_1C00001G1829	4.162e-22	96.0	COG0333@1|root,COG0333@2|Bacteria,2NQ1M@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal L32p protein family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
YHH1_k127_4328184_1	1379698.RBG1_1C00001G1828	2.296e-82	288.0	COG0416@1|root,COG0416@2|Bacteria,2NP1H@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
YHH1_k127_4328184_0	580331.Thit_1283	1.905e-105	351.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,42ER1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
YHH1_k127_4328184_2	1379698.RBG1_1C00001G1827	1.077e-59	214.0	COG0331@1|root,COG0331@2|Bacteria,2NP3V@2323|unclassified Bacteria	2|Bacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15327,ko:K15329,ko:K15355,ko:K15469	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Acyl_transf_1
YHH1_k127_4335486_2	935548.KI912159_gene2612	5.767e-08	57.0	COG2207@1|root,COG2207@2|Bacteria,1QVRF@1224|Proteobacteria,2TXHK@28211|Alphaproteobacteria,43N7M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
YHH1_k127_4335486_3	1116369.KB890024_gene2239	4.21e-05	53.0	COG5517@1|root,COG5517@2|Bacteria,1PZCZ@1224|Proteobacteria,2VCSK@28211|Alphaproteobacteria,43QM3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
YHH1_k127_4335486_1	1463909.KL585975_gene2555	1.357e-68	241.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,Methyltransf_25
YHH1_k127_4335486_0	929556.Solca_1648	3.038e-115	380.0	COG0265@1|root,COG0265@2|Bacteria,4PNUK@976|Bacteroidetes,1IRYS@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
YHH1_k127_4356684_12	1248760.ANFZ01000009_gene1382	0.0008668	42.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,2U38P@28211|Alphaproteobacteria,2K37I@204457|Sphingomonadales	204457|Sphingomonadales	P	Iron/manganese superoxide dismutases, C-terminal domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C
YHH1_k127_4356684_2	1379698.RBG1_1C00001G0818	3.268e-76	258.0	COG0605@1|root,COG0605@2|Bacteria,2NP62@2323|unclassified Bacteria	2|Bacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010269,GO:0010447,GO:0016020,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0020012,GO:0030145,GO:0030682,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052173,GO:0052200,GO:0052385,GO:0052550,GO:0052564,GO:0052567,GO:0052572,GO:0055114,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071291,GO:0071450,GO:0071451,GO:0071944,GO:0072593,GO:0075136,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.15.1.1,3.1.11.6	ko:K03601,ko:K04564	ko03430,ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map03430,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	iAF1260.b1656,iAPECO1_1312.APECO1_736,iB21_1397.B21_01616,iBWG_1329.BWG_1471,iE2348C_1286.E2348C_1742,iE2348C_1286.E2348C_4213,iEC042_1314.EC042_1825,iEC55989_1330.EC55989_1824,iECABU_c1320.ECABU_c19090,iECBD_1354.ECBD_1987,iECB_1328.ECB_01626,iECDH10B_1368.ECDH10B_1790,iECDH1ME8569_1439.ECDH1ME8569_1601,iECD_1391.ECD_01626,iECED1_1282.ECED1_1855,iECH74115_1262.ECH74115_2368,iECIAI1_1343.ECIAI1_1708,iECO103_1326.ECO103_1797,iECO111_1330.ECO111_2126,iECO26_1355.ECO26_2385,iECOK1_1307.ECOK1_1775,iECP_1309.ECP_1601,iECS88_1305.ECS88_1705,iECSE_1348.ECSE_1780,iECSF_1327.ECSF_3769,iECSP_1301.ECSP_2222,iECUMN_1333.ECUMN_1946,iECW_1372.ECW_m1823,iECs_1301.ECs2365,iEKO11_1354.EKO11_2118,iETEC_1333.ETEC_1691,iEcDH1_1363.EcDH1_1984,iEcE24377_1341.EcE24377A_1869,iEcHS_1320.EcHS_A1735,iEcSMS35_1347.EcSMS35_1542,iEcolC_1368.EcolC_1973,iG2583_1286.G2583_2051,iJO1366.b1656,iJR904.b1656,iLF82_1304.LF82_2148,iNJ661.Rv3846,iNRG857_1313.NRG857_08300,iSBO_1134.SBO_1475,iSDY_1059.SDY_1882,iSFV_1184.SFV_1678,iSF_1195.SF1684,iSFxv_1172.SFxv_1892,iSSON_1240.SSON_1500,iS_1188.S1816,iSbBS512_1146.SbBS512_E1853,iUMN146_1321.UM146_08870,iUMNK88_1353.UMNK88_2117,iUTI89_1310.UTI89_C1847,iWFL_1372.ECW_m1823,iY75_1357.Y75_RS08680,iZ_1308.Z2678,ic_1306.c2050	Sod_Fe_C,Sod_Fe_N
YHH1_k127_4356684_1	767817.Desgi_1343	2.21e-104	348.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,260DU@186807|Peptococcaceae	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
YHH1_k127_4356684_5	1232410.KI421416_gene2596	8.447e-20	105.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
YHH1_k127_4356684_7	204669.Acid345_4648	4.472e-12	79.0	COG0745@1|root,COG0745@2|Bacteria,3Y8XM@57723|Acidobacteria	57723|Acidobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
YHH1_k127_4356684_4	1379698.RBG1_1C00001G0211	4.417e-35	147.0	COG0457@1|root,COG0457@2|Bacteria,2NQ8S@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4356684_10	1289387.AUKW01000004_gene1271	3.857e-07	61.0	COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria	201174|Actinobacteria	K	AntiSigma factor	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
YHH1_k127_4356684_3	1379698.RBG1_1C00001G1618	7.374e-62	218.0	COG1595@1|root,COG1595@2|Bacteria,2NPHU@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_4356684_11	1121861.KB899920_gene2926	1.758e-05	52.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2UHNB@28211|Alphaproteobacteria,2JUGI@204441|Rhodospirillales	204441|Rhodospirillales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH1_k127_4356684_9	1379698.RBG1_1C00001G1358	2.986e-07	61.0	COG0810@1|root,COG0810@2|Bacteria,2NQ1D@2323|unclassified Bacteria	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
YHH1_k127_4356684_6	1123288.SOV_2c02820	7.579e-13	77.0	COG0810@1|root,COG0810@2|Bacteria,1VN7X@1239|Firmicutes,4H6EJ@909932|Negativicutes	909932|Negativicutes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
YHH1_k127_4356684_8	653045.Strvi_6395	4.608e-10	65.0	COG3011@1|root,COG3011@2|Bacteria,2IMHW@201174|Actinobacteria	201174|Actinobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
YHH1_k127_4356684_0	1379698.RBG1_1C00001G1888	1.061e-156	501.0	COG0468@1|root,COG0468@2|Bacteria,2NNYW@2323|unclassified Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
YHH1_k127_4400007_0	497964.CfE428DRAFT_0570	5.491e-60	213.0	COG1621@1|root,COG1621@2|Bacteria,46WGP@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
YHH1_k127_4401133_3	502025.Hoch_5906	9.816e-51	194.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,43AG6@68525|delta/epsilon subdivisions,2X63V@28221|Deltaproteobacteria,2Z38Y@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	PP2C_2
YHH1_k127_4401133_4	945713.IALB_0188	3.067e-23	111.0	COG1649@1|root,COG4733@1|root,COG1649@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	J	-	3.2.1.11,3.2.1.18,3.2.1.35	ko:K01186,ko:K01197,ko:K05988,ko:K11931,ko:K21449	ko00500,ko00511,ko00531,ko00600,ko01100,ko02026,ko04142,map00500,map00511,map00531,map00600,map01100,map02026,map04142	M00076,M00077	R04018,R07824,R07825,R10905,R11309	RC00028,RC00077	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02000,ko02042	1.B.40.2	GH33,GH66	-	DUF1983,DUF3672,Phage-tail_3
YHH1_k127_4401133_5	880073.Calab_0041	1.904e-22	115.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
YHH1_k127_4401133_6	278957.ABEA03000120_gene1234	3.503e-09	63.0	COG5652@1|root,COG5652@2|Bacteria,46WK5@74201|Verrucomicrobia,3K8DM@414999|Opitutae	414999|Opitutae	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
YHH1_k127_4401133_1	269799.Gmet_0063	7.636e-70	248.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,43STU@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
YHH1_k127_4401133_7	563040.Saut_0116	2.588e-05	57.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,42MZ6@68525|delta/epsilon subdivisions,2YN30@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
YHH1_k127_4401133_0	56780.SYN_03628	3.064e-97	326.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2MQ6Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
YHH1_k127_4401133_2	1379698.RBG1_1C00001G0367	5.5e-60	218.0	COG1253@1|root,COG1253@2|Bacteria,2NP04@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	ytfL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03699,ko:K06189	-	-	-	-	ko00000,ko02000,ko02042	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21,TerC
YHH1_k127_4447649_3	304371.MCP_0182	1.799e-06	61.0	COG3325@1|root,arCOG02552@1|root,arCOG02552@2157|Archaea,arCOG07840@2157|Archaea	2157|Archaea	G	protein contain chitin-binding domain type 3	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Beta_helix,Big_3_5,Big_5,CHB_HEX_C_1,Glyco_hydro_18,NosD,PKD
YHH1_k127_4447649_2	1123248.KB893316_gene4600	1.722e-14	88.0	COG1749@1|root,COG3055@1|root,COG1749@2|Bacteria,COG3055@2|Bacteria,4NTUT@976|Bacteroidetes	976|Bacteroidetes	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4082
YHH1_k127_4447649_1	1046627.BZARG_2521	8.318e-22	112.0	COG5184@1|root,COG5184@2|Bacteria,4NNEI@976|Bacteroidetes,1I637@117743|Flavobacteriia	976|Bacteroidetes	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF1566
YHH1_k127_4447649_0	234267.Acid_4124	7.582e-80	299.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
YHH1_k127_445860_2	243231.GSU2371	5.055e-60	217.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
YHH1_k127_445860_0	195250.CM001776_gene258	4.114e-174	554.0	COG0133@1|root,COG0133@2|Bacteria,1G0SQ@1117|Cyanobacteria,1GZ6X@1129|Synechococcus	1117|Cyanobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH1_k127_445860_4	395493.BegalDRAFT_1051	1.461e-40	158.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,4601W@72273|Thiotrichales	72273|Thiotrichales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH1_k127_445860_1	396588.Tgr7_2798	1.016e-63	227.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1WW6P@135613|Chromatiales	135613|Chromatiales	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
YHH1_k127_445860_3	351160.RCIX86	2.065e-58	219.0	COG0477@1|root,arCOG00132@2157|Archaea,2XYHV@28890|Euryarchaeota,2NAK2@224756|Methanomicrobia	224756|Methanomicrobia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH1_k127_445860_5	1049564.TevJSym_ag00400	2.226e-29	122.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1J4GF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0421	Glycos_trans_3N,Glycos_transf_3
YHH1_k127_4501038_0	1379698.RBG1_1C00001G1641	7.603e-165	525.0	COG0519@1|root,COG0519@2|Bacteria,2NNRS@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.3.1.128,6.3.5.2	ko:K01951,ko:K03790	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002,ko03009	-	-	iLJ478.TM1820	GATase,GMP_synt_C,NAD_synthase
YHH1_k127_4501038_5	1162668.LFE_0393	2.194e-19	99.0	COG4447@1|root,COG4447@2|Bacteria,3J16A@40117|Nitrospirae	40117|Nitrospirae	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_4501038_4	1242864.D187_001018	8.711e-25	113.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,42RPV@68525|delta/epsilon subdivisions,2WNQC@28221|Deltaproteobacteria,2Z0E4@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_4501038_6	671143.DAMO_2528	8.805e-19	96.0	COG2177@1|root,COG2177@2|Bacteria,2NPIM@2323|unclassified Bacteria	2|Bacteria	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
YHH1_k127_4501038_3	1379698.RBG1_1C00001G0315	3.737e-32	139.0	COG4942@1|root,COG4942@2|Bacteria,2NPDY@2323|unclassified Bacteria	2|Bacteria	D	Peptidase family M23	envC	GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
YHH1_k127_4501038_2	1379698.RBG1_1C00001G0316	1.045e-37	157.0	COG2812@1|root,COG2812@2|Bacteria,2NPH0@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
YHH1_k127_4501038_1	880073.Calab_1952	3.404e-60	218.0	COG1774@1|root,COG1774@2|Bacteria,2NPEB@2323|unclassified Bacteria	2|Bacteria	S	PSP1 C-terminal conserved region	yaaT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	PSP1
YHH1_k127_4502131_1	1379698.RBG1_1C00001G0607	2.627e-148	497.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
YHH1_k127_4502131_5	522306.CAP2UW1_4074	8.171e-10	62.0	COG2331@1|root,COG2331@2|Bacteria,1PVEY@1224|Proteobacteria,2VYJG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH1_k127_4502131_2	264732.Moth_1263	6.229e-27	114.0	COG3439@1|root,COG3439@2|Bacteria,1VA5R@1239|Firmicutes,24NQI@186801|Clostridia	186801|Clostridia	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
YHH1_k127_4502131_3	326427.Cagg_1564	3.818e-26	113.0	COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
YHH1_k127_4502131_0	649747.HMPREF0083_06089	8.884e-171	555.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,26TZM@186822|Paenibacillaceae	91061|Bacilli	E	oligoendopeptidase F	yjbG	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YHH1_k127_4502131_4	1220534.B655_1754	5.198e-14	73.0	COG3467@1|root,arCOG00520@2157|Archaea,2Y26T@28890|Euryarchaeota,23PV6@183925|Methanobacteria	183925|Methanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
YHH1_k127_4505125_8	1296415.JACC01000043_gene55	1.452e-07	63.0	COG1044@1|root,COG1044@2|Bacteria,4PP69@976|Bacteroidetes	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4505125_7	1379698.RBG1_1C00001G0763	2.658e-10	74.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YHH1_k127_4505125_9	1296416.JACB01000050_gene5326	0.0006342	53.0	COG1044@1|root,COG1044@2|Bacteria,4PI4N@976|Bacteroidetes,1IGAK@117743|Flavobacteriia,2YKJV@290174|Aquimarina	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4505125_5	204669.Acid345_1217	1.185e-23	104.0	COG5646@1|root,COG5646@2|Bacteria,3Y5GZ@57723|Acidobacteria,2JNWJ@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
YHH1_k127_4505125_2	1121930.AQXG01000008_gene175	1.905e-84	295.0	COG4826@1|root,COG4826@2|Bacteria,4NG1G@976|Bacteroidetes,1IRRU@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
YHH1_k127_4505125_4	868131.MSWAN_2301	2.003e-29	121.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,23P3X@183925|Methanobacteria	183925|Methanobacteria	V	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
YHH1_k127_4505125_0	368407.Memar_2362	4.333e-126	415.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,2N94P@224756|Methanomicrobia	224756|Methanomicrobia	I	PFAM Thiolase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF692.Mbar_A0550	Thiolase_C,Thiolase_N
YHH1_k127_4505125_1	593750.Metfor_0023	8.609e-111	365.0	COG3425@1|root,arCOG01767@2157|Archaea,2XTWE@28890|Euryarchaeota,2N99Q@224756|Methanomicrobia	224756|Methanomicrobia	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,HMG_CoA_synt_N
YHH1_k127_4526880_2	1379698.RBG1_1C00001G0340	3.02e-80	273.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
YHH1_k127_4526880_1	1379698.RBG1_1C00001G0341	1.259e-142	464.0	COG0766@1|root,COG0766@2|Bacteria,2NNUV@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
YHH1_k127_4526880_5	237368.SCABRO_02876	3.736e-25	112.0	2CA4A@1|root,32RQK@2|Bacteria,2J0BM@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
YHH1_k127_4526880_4	1459636.NTE_00759	3.699e-36	143.0	COG1027@1|root,COG1670@1|root,arCOG00842@2157|Archaea,arCOG01750@2157|Archaea,41S9C@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
YHH1_k127_4526880_0	1379698.RBG1_1C00001G0334	6.522e-262	816.0	COG2987@1|root,COG2987@2|Bacteria,2NP09@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_0688	Urocanase,Urocanase_C,Urocanase_N
YHH1_k127_4526880_3	1285586.H131_02313	2.861e-60	216.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,4HAVY@91061|Bacilli,3IW77@400634|Lysinibacillus	91061|Bacilli	F	Imidazolone-5-propionate hydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
YHH1_k127_4548034_1	1379698.RBG1_1C00001G0237	1.605e-34	150.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,LVIVD
YHH1_k127_4548034_0	1121406.JAEX01000002_gene1142	2.936e-72	254.0	COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria,42SIB@68525|delta/epsilon subdivisions,2WPCP@28221|Deltaproteobacteria,2ME8A@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH1_k127_4557701_1	382245.ASA_3031	1.979e-20	96.0	2EGQC@1|root,33AGI@2|Bacteria,1NGA3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PsiF_repeat
YHH1_k127_4557701_0	338963.Pcar_0118	5.984e-111	370.0	COG3568@1|root,COG3568@2|Bacteria,1RA4I@1224|Proteobacteria	1224|Proteobacteria	L	deoxyribonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding,Exo_endo_phos,HHH_3,LTD
YHH1_k127_4595820_0	1379698.RBG1_1C00001G1003	1.387e-147	488.0	COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding protein 2	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
YHH1_k127_4595820_5	1379698.RBG1_1C00001G1001	1.412e-32	137.0	COG1792@1|root,COG1792@2|Bacteria,2NPNX@2323|unclassified Bacteria	2|Bacteria	M	Cell shape-determining protein MreC	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
YHH1_k127_4595820_3	1379698.RBG1_1C00001G1000	7.775e-60	210.0	COG1762@1|root,COG1762@2|Bacteria,2NPVC@2323|unclassified Bacteria	2|Bacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
YHH1_k127_4595820_8	648996.Theam_1326	4.479e-16	80.0	COG2835@1|root,COG2835@2|Bacteria,2G4D1@200783|Aquificae	200783|Aquificae	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
YHH1_k127_4595820_1	1379698.RBG1_1C00001G0998	5.844e-129	419.0	COG0825@1|root,COG0825@2|Bacteria,2NNVQ@2323|unclassified Bacteria	2|Bacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accA	ACCA
YHH1_k127_4595820_4	1286171.EAL2_c03820	7.586e-55	205.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,25UW9@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
YHH1_k127_4595820_6	713586.KB900536_gene2502	2.515e-32	137.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,1RRUD@1236|Gammaproteobacteria,1WX3T@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
YHH1_k127_4595820_2	1379698.RBG1_1C00001G0996	7.673e-109	356.0	COG0463@1|root,COG0463@2|Bacteria,2NS3Y@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
YHH1_k127_4595820_7	518766.Rmar_0571	1.664e-22	104.0	COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria,4NEE5@976|Bacteroidetes,1FIQ3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
YHH1_k127_4606189_1	1519464.HY22_00560	4.44e-62	239.0	COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Reprolysin_5
YHH1_k127_4606189_5	264462.Bd2133	7.579e-06	58.0	COG0729@1|root,COG3210@1|root,COG0729@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K07277,ko:K07278,ko:K21449	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,1.B.33.2.4,1.B.40.2	-	-	Bac_surface_Ag,Beta_helix,PATR,POTRA,Peptidase_S74
YHH1_k127_4606189_4	1379698.RBG1_1C00001G0198	2.999e-15	89.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YHH1_k127_4606189_2	383372.Rcas_0060	5.633e-46	192.0	COG1413@1|root,COG2909@1|root,COG3947@1|root,COG1413@2|Bacteria,COG2909@2|Bacteria,COG3947@2|Bacteria,2G6RU@200795|Chloroflexi,375JR@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HEAT_2,Trans_reg_C
YHH1_k127_4606189_6	1286632.P278_00950	8.595e-06	55.0	2E991@1|root,333HB@2|Bacteria,4NZDJ@976|Bacteroidetes,1I93U@117743|Flavobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
YHH1_k127_4606189_3	313596.RB2501_11942	3.565e-44	172.0	COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,1HYWC@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH1_k127_4606189_0	153948.NAL212_1353	6.566e-80	271.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,372F6@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin_4
YHH1_k127_4625439_0	1487953.JMKF01000014_gene6219	1.198e-57	226.0	COG2202@1|root,COG3829@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria,1HHXQ@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CBS,CheB_methylest,CheR,CheR_N,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
YHH1_k127_4628815_0	404380.Gbem_1121	3.004e-17	89.0	COG4380@1|root,COG4380@2|Bacteria,1NJYS@1224|Proteobacteria,42X1E@68525|delta/epsilon subdivisions,2WTEE@28221|Deltaproteobacteria,43VPV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative bacterial lipoprotein (DUF799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF799
YHH1_k127_4628815_5	1380391.JIAS01000019_gene1199	0.0008902	49.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,2JR1T@204441|Rhodospirillales	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
YHH1_k127_4628815_2	126957.SMAR010917-PA	2.763e-08	65.0	KOG2177@1|root,KOG2177@2759|Eukaryota,38F95@33154|Opisthokonta,3BA7J@33208|Metazoa,3CZWX@33213|Bilateria,41W93@6656|Arthropoda	33208|Metazoa	O	Zinc ion binding	nhl-1	GO:0003008,GO:0003012,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007610,GO:0007626,GO:0008150,GO:0008152,GO:0008270,GO:0008345,GO:0009653,GO:0009987,GO:0010927,GO:0016043,GO:0016567,GO:0016740,GO:0019538,GO:0019725,GO:0019787,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030537,GO:0031032,GO:0031674,GO:0032446,GO:0032501,GO:0032502,GO:0032989,GO:0036211,GO:0042592,GO:0042692,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0046716,GO:0046872,GO:0046914,GO:0048468,GO:0048646,GO:0048747,GO:0048856,GO:0048869,GO:0051146,GO:0055001,GO:0055002,GO:0060249,GO:0061061,GO:0065007,GO:0065008,GO:0070647,GO:0070925,GO:0071704,GO:0071840,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:0140096,GO:1901564	2.3.2.27	ko:K11997,ko:K12035	ko05206,map05206	-	-	-	ko00000,ko00001,ko01000,ko03019,ko04121	-	-	-	NHL,zf-B_box,zf-C3HC4,zf-RING_UBOX
YHH1_k127_4628815_3	589865.DaAHT2_0752	7.716e-08	64.0	28WYN@1|root,2ZIXP@2|Bacteria,1NRMH@1224|Proteobacteria,42YM3@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YHH1_k127_4628815_1	589865.DaAHT2_0394	3.949e-11	75.0	28WYN@1|root,30ZZ9@2|Bacteria,1NPVB@1224|Proteobacteria,42XW6@68525|delta/epsilon subdivisions,2WTBQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YHH1_k127_4628815_4	634498.mru_0338	2.054e-07	63.0	COG1305@1|root,arCOG00373@1|root,arCOG02488@1|root,arCOG02555@1|root,arCOG00373@2157|Archaea,arCOG02486@2157|Archaea,arCOG02488@2157|Archaea,arCOG02555@2157|Archaea	2157|Archaea	E	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
YHH1_k127_4631651_1	1120746.CCNL01000017_gene2423	2.077e-70	249.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
YHH1_k127_4631651_0	525897.Dbac_1173	1.323e-268	831.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2M986@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
YHH1_k127_4631651_2	1521187.JPIM01000013_gene2749	8.932e-48	175.0	COG1027@1|root,COG1027@2|Bacteria,2G5IV@200795|Chloroflexi,37644@32061|Chloroflexia	32061|Chloroflexia	C	PFAM fumarate lyase	-	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
YHH1_k127_4650830_1	1191523.MROS_1192	2.212e-45	175.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_4650830_0	1191523.MROS_1192	7.312e-50	188.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_4650830_2	1052684.PPM_3563	1.443e-19	93.0	2C7E0@1|root,330TX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4669290_2	118005.AWNK01000001_gene2101	3.749e-55	201.0	2CAZH@1|root,2Z7RU@2|Bacteria	2|Bacteria	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
YHH1_k127_4669290_0	1128421.JAGA01000003_gene2923	0.0	1014.0	COG1053@1|root,COG1053@2|Bacteria,2NQMR@2323|unclassified Bacteria	2|Bacteria	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH1_k127_4669290_1	1123508.JH636439_gene1816	1.048e-106	353.0	COG0479@1|root,COG0479@2|Bacteria,2IX7J@203682|Planctomycetes	203682|Planctomycetes	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
YHH1_k127_4682604_4	96561.Dole_0426	6.769e-18	85.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2MHU3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,sCache_3_2
YHH1_k127_4682604_1	1278073.MYSTI_07405	5.54e-88	297.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42ZGK@68525|delta/epsilon subdivisions,2WUTG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_4682604_2	861299.J421_1766	5.334e-74	258.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01421,ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
YHH1_k127_4682604_3	419610.Mext_3422	2.39e-51	199.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2U5VQ@28211|Alphaproteobacteria,1JT3V@119045|Methylobacteriaceae	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
YHH1_k127_4682604_0	1191523.MROS_0749	2.179e-171	547.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH1_k127_4708581_6	1131812.JQMS01000001_gene1778	1.187e-11	66.0	COG2350@1|root,COG2350@2|Bacteria,4NR5W@976|Bacteroidetes,1I5PD@117743|Flavobacteriia,2NU9F@237|Flavobacterium	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4708581_7	1121381.JNIV01000106_gene1932	1.877e-05	54.0	COG2318@1|root,COG2318@2|Bacteria,1WMWY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
YHH1_k127_4708581_8	1382359.JIAL01000001_gene1945	0.0009716	48.0	COG4319@1|root,COG4319@2|Bacteria,3Y4YW@57723|Acidobacteria,2JJHI@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
YHH1_k127_4708581_3	204536.SULAZ_0249	9.236e-38	149.0	COG0693@1|root,COG0693@2|Bacteria,2G50X@200783|Aquificae	200783|Aquificae	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
YHH1_k127_4708581_5	1365176.N186_01445	1.59e-32	133.0	COG1335@1|root,arCOG01943@2157|Archaea,2XQK1@28889|Crenarchaeota	28889|Crenarchaeota	Q	PFAM Isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
YHH1_k127_4708581_2	1379698.RBG1_1C00001G1107	3.088e-74	265.0	COG1207@1|root,COG1207@2|Bacteria,2NQ8F@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_4
YHH1_k127_4708581_1	1162668.LFE_2206	2.686e-133	433.0	COG1085@1|root,COG1085@2|Bacteria,3J0ER@40117|Nitrospirae	40117|Nitrospirae	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
YHH1_k127_4708581_0	1519464.HY22_03430	8.93e-144	472.0	COG0297@1|root,COG0297@2|Bacteria,1FDT0@1090|Chlorobi	1090|Chlorobi	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
YHH1_k127_4708581_4	765420.OSCT_1275	6.758e-37	157.0	COG1807@1|root,COG1807@2|Bacteria,2G8IK@200795|Chloroflexi,375EI@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4738146_1	396588.Tgr7_2086	1.187e-08	57.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,1WWU7@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
YHH1_k127_4738146_0	1121396.KB893052_gene3420	1.304e-65	249.0	COG1193@1|root,COG1193@2|Bacteria,1NX1A@1224|Proteobacteria,4305V@68525|delta/epsilon subdivisions,2WV73@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Protein-arginine deiminase (PAD) middle domain	-	-	-	-	-	-	-	-	-	-	-	-	PAD
YHH1_k127_4741366_4	886293.Sinac_2076	7.332e-47	173.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
YHH1_k127_4741366_1	861299.J421_4544	2.402e-77	269.0	COG0697@1|root,COG0697@2|Bacteria,1ZTM7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_4741366_3	309799.DICTH_0708	7.468e-60	211.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
YHH1_k127_4741366_7	1123008.KB905693_gene1422	1.476e-09	61.0	arCOG05093@1|root,339N6@2|Bacteria,4NYIM@976|Bacteroidetes,2FVF5@200643|Bacteroidia,22YYW@171551|Porphyromonadaceae	976|Bacteroidetes	S	Winged helix-turn-helix domain (DUF2582)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2582
YHH1_k127_4741366_2	1234364.AMSF01000061_gene2084	1.929e-60	234.0	COG0793@1|root,COG0793@2|Bacteria,1N4T9@1224|Proteobacteria,1SE36@1236|Gammaproteobacteria,1X70X@135614|Xanthomonadales	135614|Xanthomonadales	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ_2
YHH1_k127_4741366_5	246197.MXAN_6281	7.843e-41	163.0	COG1378@1|root,COG1378@2|Bacteria,1N9ZU@1224|Proteobacteria,42NVG@68525|delta/epsilon subdivisions,2WMD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
YHH1_k127_4741366_6	568816.Acin_0518	2.482e-16	89.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4H409@909932|Negativicutes	909932|Negativicutes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N,RecO_N_2
YHH1_k127_4741366_0	1379698.RBG1_1C00001G1633	7.346e-211	662.0	COG0423@1|root,COG0423@2|Bacteria,2NNN9@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
YHH1_k127_4747177_0	1232410.KI421413_gene852	6.218e-36	141.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	pcaC	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
YHH1_k127_4747177_1	666681.M301_2394	6.147e-25	106.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,2VV31@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
YHH1_k127_4768091_0	153721.MYP_33	3.102e-76	269.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,47NM0@768503|Cytophagia	976|Bacteroidetes	E	PFAM Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
YHH1_k127_4768091_1	1122221.JHVI01000004_gene147	1.376e-29	121.0	2CMS6@1|root,32SFE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH1_k127_4778509_0	391612.CY0110_23926	4.592e-79	275.0	COG4798@1|root,COG4798@2|Bacteria,1GQ94@1117|Cyanobacteria,3KKUY@43988|Cyanothece	1117|Cyanobacteria	S	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
YHH1_k127_4778509_2	313628.LNTAR_20888	1.216e-05	57.0	COG1889@1|root,COG1889@2|Bacteria	2|Bacteria	J	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YHH1_k127_4778509_1	1340493.JNIF01000003_gene3655	4.74e-15	87.0	COG4798@1|root,COG4798@2|Bacteria,3Y5JR@57723|Acidobacteria	57723|Acidobacteria	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
YHH1_k127_4795637_2	1246995.AFR_08045	3.227e-67	248.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4D9CY@85008|Micromonosporales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ykoD	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
YHH1_k127_4795637_0	665952.HMPREF1015_00240	8.386e-182	582.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,1ZATI@1386|Bacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
YHH1_k127_4795637_3	1379698.RBG1_1C00001G0750	6.023e-38	151.0	COG2143@1|root,COG2143@2|Bacteria	2|Bacteria	O	COG2143 Thioredoxin-related protein	soxS	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	Thioredoxin_2,Thioredoxin_7
YHH1_k127_4795637_1	1379698.RBG1_1C00001G1499	2.501e-151	490.0	COG0403@1|root,COG0403@2|Bacteria,2NNP1@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204	1.4.4.2	ko:K00281,ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
YHH1_k127_4829227_2	429009.Adeg_1149	1.158e-88	309.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,42ER2@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
YHH1_k127_4829227_1	204669.Acid345_1883	2.274e-140	452.0	COG2876@1|root,COG2876@2|Bacteria,3Y32G@57723|Acidobacteria,2JIXH@204432|Acidobacteriia	204432|Acidobacteriia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
YHH1_k127_4829227_0	1511.CLOST_1149	9.385e-159	520.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,25QY6@186804|Peptostreptococcaceae	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YHH1_k127_4830518_7	1379698.RBG1_1C00001G0712	7.311e-30	121.0	COG0612@1|root,COG0612@2|Bacteria,2NQPM@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_4830518_1	1379698.RBG1_1C00001G0711	8.667e-149	488.0	COG0612@1|root,COG0612@2|Bacteria,2NQHV@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	ymxG	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_4830518_2	247633.GP2143_12631	3.843e-67	235.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1J53F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
YHH1_k127_4830518_6	694427.Palpr_2946	4.601e-31	126.0	2BFHQ@1|root,329BH@2|Bacteria,4P73M@976|Bacteroidetes,2FZWT@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4830518_3	525909.Afer_1722	1.217e-50	187.0	COG2353@1|root,COG2353@2|Bacteria,2GJFT@201174|Actinobacteria,4CN3A@84992|Acidimicrobiia	84992|Acidimicrobiia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
YHH1_k127_4830518_0	1379698.RBG1_1C00001G0830	1.175e-215	690.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YHH1_k127_4830518_4	1169144.KB910934_gene4255	8.542e-45	168.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,1ZFX8@1386|Bacillus	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH1_k127_4830518_10	886293.Sinac_0423	1.797e-10	69.0	COG3212@1|root,COG3212@2|Bacteria,2J0WH@203682|Planctomycetes	203682|Planctomycetes	S	Putative beta-lactamase-inhibitor-like, PepSY-like	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
YHH1_k127_4830518_9	1501230.ET33_30925	8.507e-15	76.0	COG1476@1|root,COG1476@2|Bacteria,1VFN1@1239|Firmicutes,4HSHB@91061|Bacilli,270T1@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
YHH1_k127_4830518_5	717606.PaecuDRAFT_2294	5.415e-38	159.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH1_k127_4830518_8	5722.XP_001329437.1	2.761e-17	95.0	COG0666@1|root,KOG0504@2759|Eukaryota	2759|Eukaryota	I	protein ubiquitination	-	-	-	ko:K15502,ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447
YHH1_k127_4865780_0	1379698.RBG1_1C00001G1165	8.512e-224	709.0	COG0495@1|root,COG0495@2|Bacteria,2NNQH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
YHH1_k127_4867455_3	118173.KB235914_gene3853	4.823e-25	114.0	COG2755@1|root,COG2755@2|Bacteria,1G31T@1117|Cyanobacteria,1H8QX@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH1_k127_4867455_2	1288826.MSNKSG1_06853	9.204e-26	116.0	COG0110@1|root,COG0110@2|Bacteria,1RDQE@1224|Proteobacteria,1S3RJ@1236|Gammaproteobacteria,466XH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Acetyltransferase (Isoleucine patch superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
YHH1_k127_4867455_0	177437.HRM2_19780	3.565e-52	199.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria,2MJPQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Transmembrane exosortase (Exosortase_EpsH)	epsH	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
YHH1_k127_4867455_4	941449.dsx2_1167	3.725e-21	102.0	COG1269@1|root,COG1269@2|Bacteria,1RF6T@1224|Proteobacteria,42RED@68525|delta/epsilon subdivisions,2WNV7@28221|Deltaproteobacteria,2MC3C@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM EpsI family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
YHH1_k127_4867455_5	1385935.N836_03955	2.566e-08	65.0	COG0463@1|root,COG0463@2|Bacteria,1G4DE@1117|Cyanobacteria,1H9EJ@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_4867455_6	62928.azo3265	3.608e-06	58.0	COG1215@1|root,COG1215@2|Bacteria,1RF99@1224|Proteobacteria,2VWU1@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_4867455_1	1307759.JOMJ01000004_gene2503	1.026e-29	128.0	COG3307@1|root,COG3307@2|Bacteria,1QTKA@1224|Proteobacteria,42VD4@68525|delta/epsilon subdivisions,2WRBR@28221|Deltaproteobacteria,2MAIC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH1_k127_4871312_3	1382306.JNIM01000001_gene2748	1.688e-57	214.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
YHH1_k127_4871312_2	1379698.RBG1_1C00001G1156	1.592e-67	243.0	COG0618@1|root,COG0618@2|Bacteria,2NPK0@2323|unclassified Bacteria	2|Bacteria	S	DHH family	nrnA	GO:0008150,GO:0040007	2.7.7.72,3.1.13.3,3.1.3.7	ko:K00974,ko:K06881	ko00920,ko01100,ko01120,ko03013,map00920,map01100,map01120,map03013	-	R00188,R00508,R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03400	-	-	-	DHH,DHHA1
YHH1_k127_4871312_4	555778.Hneap_1466	8.232e-18	87.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1WYHM@135613|Chromatiales	135613|Chromatiales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
YHH1_k127_4871312_0	1379698.RBG1_1C00001G1153	9.245e-234	746.0	COG0532@1|root,COG0532@2|Bacteria,2NNRG@2323|unclassified Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
YHH1_k127_4871312_1	1379698.RBG1_1C00001G1152	5.083e-111	372.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
YHH1_k127_4872699_3	1379698.RBG1_1C00001G1004	5.303e-118	390.0	COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria	2|Bacteria	D	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
YHH1_k127_4872699_7	929556.Solca_4057	3.42e-16	92.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IQVH@117747|Sphingobacteriia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
YHH1_k127_4872699_2	1379698.RBG1_1C00001G1008	2.08e-125	410.0	COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
YHH1_k127_4872699_1	351607.Acel_1114	1.937e-137	444.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4ES5V@85013|Frankiales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
YHH1_k127_4872699_0	945713.IALB_1271	1.701e-163	523.0	COG0126@1|root,COG0126@2|Bacteria	2|Bacteria	F	phosphoglycerate kinase activity	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
YHH1_k127_4872699_4	1121430.JMLG01000009_gene437	2.093e-79	272.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
YHH1_k127_4872699_8	412965.COSY_0976	2.204e-07	58.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1JB58@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Preprotein translocase SecG subunit	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
YHH1_k127_4872699_5	1280944.HY17_04460	1.59e-42	173.0	COG3723@1|root,COG3723@2|Bacteria,1QZ88@1224|Proteobacteria	1224|Proteobacteria	L	RecT family	-	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	RecT
YHH1_k127_4930411_1	926550.CLDAP_06530	2.417e-44	168.0	COG0006@1|root,COG0006@2|Bacteria,2G5J8@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
YHH1_k127_4930411_0	204669.Acid345_4117	4.132e-60	232.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
YHH1_k127_4936587_0	926569.ANT_20080	3.537e-34	151.0	COG1520@1|root,COG1520@2|Bacteria,2G945@200795|Chloroflexi	200795|Chloroflexi	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4944611_0	1379698.RBG1_1C00001G0186	0.0	1081.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2NNNY@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.3.13,2.7.9.1	ko:K01006,ko:K22424	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH1_k127_4944611_1	1379698.RBG1_1C00001G0509	6.377e-234	745.0	COG1042@1|root,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria	2|Bacteria	C	synthetase (ADP forming), alpha	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
YHH1_k127_4944611_2	309799.DICTH_1169	5.917e-96	326.0	COG0008@1|root,COG0008@2|Bacteria	2|Bacteria	J	glutamate-tRNA ligase activity	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH1_k127_4947670_2	395495.Lcho_4220	2.657e-16	79.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2VJ4X@28216|Betaproteobacteria,1KJ6E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
YHH1_k127_4947670_0	1095769.CAHF01000018_gene822	1.244e-189	599.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2VHEX@28216|Betaproteobacteria,472KJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
YHH1_k127_4947670_1	933262.AXAM01000064_gene591	4.115e-30	121.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,42N1Q@68525|delta/epsilon subdivisions,2WJJS@28221|Deltaproteobacteria,2MJ72@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
YHH1_k127_4964522_3	653733.Selin_2220	1.034e-27	114.0	COG0853@1|root,COG0853@2|Bacteria	2|Bacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0016485,GO:0016540,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_0139,iYL1228.KPN_00139	Asp_decarbox
YHH1_k127_4964522_1	1042163.BRLA_c000720	9.879e-65	229.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,26RIB@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
YHH1_k127_4964522_2	1379698.RBG1_1C00001G0311	8.603e-32	128.0	COG0799@1|root,COG0799@2|Bacteria,2NPYI@2323|unclassified Bacteria	2|Bacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	2.7.7.18	ko:K00969,ko:K09710	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RsfS
YHH1_k127_4964522_0	1379698.RBG1_1C00001G0312	1.641e-95	316.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
YHH1_k127_4966592_0	1496688.ER33_07850	4.332e-56	216.0	COG2931@1|root,COG3209@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1G39H@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,HemolysinCabind,RHS_repeat
YHH1_k127_4966592_1	1499967.BAYZ01000105_gene3503	8.98e-09	66.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF5011
YHH1_k127_4974389_1	84531.JMTZ01000001_gene2271	3.064e-14	85.0	COG3291@1|root,COG3420@1|root,COG4935@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.11.10,3.4.21.50,3.4.24.25,3.4.24.3	ko:K01337,ko:K01387,ko:K05994,ko:K08604,ko:K14645,ko:K20276	ko02024,ko05110,ko05111,map02024,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	-	-	-	Inhibitor_I9,LVIVD,PKD,P_proprotein,Peptidase_M14,Peptidase_S8
YHH1_k127_4974389_0	653733.Selin_1349	2.294e-47	176.0	COG4843@1|root,COG4843@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
YHH1_k127_5041488_4	1229172.JQFA01000004_gene1611	0.0009028	47.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H8H6@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9
YHH1_k127_5041488_0	945713.IALB_0461	1.123e-91	326.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH1_k127_5041488_1	411490.ANACAC_00232	5.223e-91	310.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia	186801|Clostridia	E	abc transporter atp-binding protein	glnQ1	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
YHH1_k127_5041488_2	573370.DMR_30950	3.246e-53	195.0	COG0765@1|root,COG0765@2|Bacteria,1MWF0@1224|Proteobacteria,42NEI@68525|delta/epsilon subdivisions,2WJP9@28221|Deltaproteobacteria,2M8HK@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
YHH1_k127_5041488_3	1379698.RBG1_1C00001G1516	3.114e-37	162.0	COG2982@1|root,COG2982@2|Bacteria,2NRT5@2323|unclassified Bacteria	2|Bacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289,ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA,AsmA_1,AsmA_2,DUF3971,DctA-YdbH
YHH1_k127_5060080_1	349521.HCH_04972	1.229e-45	166.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XHUG@135619|Oceanospirillales	135619|Oceanospirillales	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_5060080_0	396588.Tgr7_1549	3.075e-131	424.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1WW21@135613|Chromatiales	135613|Chromatiales	M	UTP-glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YHH1_k127_5060080_2	631362.Thi970DRAFT_03932	9.625e-41	153.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1WW39@135613|Chromatiales	135613|Chromatiales	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
YHH1_k127_5086450_0	1232410.KI421426_gene1450	1.006e-97	331.0	COG3021@1|root,COG3021@2|Bacteria,1MWFK@1224|Proteobacteria,42QIQ@68525|delta/epsilon subdivisions,2WM7F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH1_k127_5086450_2	1485544.JQKP01000011_gene720	3.194e-19	89.0	COG4095@1|root,COG4095@2|Bacteria,1N759@1224|Proteobacteria,2VVPU@28216|Betaproteobacteria,44VZK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
YHH1_k127_5086450_1	1379698.RBG1_1C00001G0462	4.947e-66	239.0	COG2067@1|root,COG2067@2|Bacteria,2NPVZ@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5091814_2	1121904.ARBP01000006_gene4059	6.52e-52	188.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47N7Y@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
YHH1_k127_5091814_3	690850.Desaf_0357	5.645e-22	97.0	COG2155@1|root,COG2155@2|Bacteria,1N77I@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
YHH1_k127_5091814_1	945713.IALB_2990	1.286e-83	284.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4397
YHH1_k127_5091814_0	1279017.AQYJ01000028_gene2405	8.413e-152	491.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
YHH1_k127_5095779_0	1379698.RBG1_1C00001G1245	6.54e-39	166.0	COG1629@1|root,COG4771@2|Bacteria,2NRGW@2323|unclassified Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YHH1_k127_5095779_1	722419.PH505_bq00020	2.957e-36	154.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria,2Q0ZC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
YHH1_k127_5099367_2	204669.Acid345_4293	2.513e-19	98.0	COG2823@1|root,COG2823@2|Bacteria,3Y99E@57723|Acidobacteria,2JP08@204432|Acidobacteriia	204432|Acidobacteriia	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5099367_0	234267.Acid_4165	6.36e-82	283.0	COG0451@1|root,COG0451@2|Bacteria,3Y7GG@57723|Acidobacteria	57723|Acidobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
YHH1_k127_5099367_1	378806.STAUR_2272	8.063e-29	117.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2YVJI@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YHH1_k127_510273_4	635013.TherJR_2833	7.756e-33	140.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,24A5A@186801|Clostridia,261XD@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
YHH1_k127_510273_0	401526.TcarDRAFT_2495	1.223e-254	820.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4H20U@909932|Negativicutes	909932|Negativicutes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH1_k127_510273_2	1379698.RBG1_1C00001G1766	7.307e-95	331.0	COG4365@1|root,COG4365@2|Bacteria,2NP8Q@2323|unclassified Bacteria	2|Bacteria	S	Bacillithiol biosynthesis BshC	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
YHH1_k127_510273_1	1379698.RBG1_1C00001G1765	4.798e-129	426.0	COG0438@1|root,COG0438@2|Bacteria,2NNTN@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_510273_3	1379698.RBG1_1C00001G1764	1.637e-57	210.0	COG2120@1|root,COG2120@2|Bacteria,2NPAV@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
YHH1_k127_5140771_3	880073.Calab_0921	6.179e-28	125.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
YHH1_k127_5140771_1	1379698.RBG1_1C00001G0595	9.162e-133	449.0	COG1874@1|root,COG1874@2|Bacteria,2NRR5@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 35	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_35,Glyco_hydro_42,Glyco_hydro_42M,Sulfotransfer_2
YHH1_k127_5140771_0	339671.Asuc_1161	1.305e-151	497.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1Y9NE@135625|Pasteurellales	135625|Pasteurellales	M	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YHH1_k127_5140771_2	1379698.RBG1_1C00001G1437	1.593e-40	158.0	COG4912@1|root,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YHH1_k127_5142656_4	1379698.RBG1_1C00001G1819	1.246e-07	53.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5142656_1	1379698.RBG1_1C00001G1819	1.745e-154	520.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5142656_0	1379698.RBG1_1C00001G1819	3.549e-157	530.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5142656_2	304371.MCP_2555	3.252e-66	241.0	COG0477@1|root,arCOG00132@2157|Archaea,2XW9U@28890|Euryarchaeota	28890|Euryarchaeota	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
YHH1_k127_5142656_3	1304888.ATWF01000001_gene1034	6.609e-08	57.0	COG5001@1|root,COG5001@2|Bacteria,2GEJ3@200930|Deferribacteres	2|Bacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,EAL,GAF,GAF_2,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg,dCache_3
YHH1_k127_5144352_6	29581.BW37_03287	1.808e-19	93.0	COG2133@1|root,COG2133@2|Bacteria,1R86D@1224|Proteobacteria,2VTBE@28216|Betaproteobacteria,475Z6@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YHH1_k127_5144352_3	765869.BDW_11880	3.983e-34	142.0	COG0847@1|root,COG2378@1|root,COG0847@2|Bacteria,COG2378@2|Bacteria,1PER2@1224|Proteobacteria,42WAS@68525|delta/epsilon subdivisions,2MUS2@213481|Bdellovibrionales,2X5KG@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T,WYL
YHH1_k127_5144352_0	350688.Clos_1187	4.975e-148	484.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,36DCC@31979|Clostridiaceae	186801|Clostridia	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
YHH1_k127_5144352_2	1480694.DC28_03280	1.635e-36	140.0	COG0393@1|root,COG0393@2|Bacteria	2|Bacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
YHH1_k127_5144352_4	880073.Calab_0082	1.173e-31	130.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_5144352_1	1191523.MROS_0404	3.956e-96	325.0	COG3342@1|root,COG3342@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,TPR_16,TPR_19
YHH1_k127_5144352_7	459349.CLOAM0553	5.031e-19	94.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	rnaZ	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
YHH1_k127_5168972_14	1123508.JH636440_gene2904	1.235e-39	169.0	COG5002@1|root,COG5002@2|Bacteria,2IXHW@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
YHH1_k127_5168972_11	926560.KE387023_gene2289	2.07e-95	340.0	COG3852@1|root,COG3852@2|Bacteria,1WMD2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YHH1_k127_5168972_3	251229.Chro_1451	8.541e-214	677.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,3VIV0@52604|Pleurocapsales	1117|Cyanobacteria	KOT	Response regulator receiver domain	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
YHH1_k127_5168972_6	428125.CLOLEP_01561	2.232e-180	576.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WGJQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH1_k127_5168972_1	1121335.Clst_1649	1.517e-242	766.0	COG0143@1|root,COG0143@2|Bacteria,1V0G4@1239|Firmicutes,249DC@186801|Clostridia,3WH8J@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
YHH1_k127_5168972_15	999413.HMPREF1094_02057	1.098e-22	107.0	28SAX@1|root,2ZEMX@2|Bacteria,1V2C8@1239|Firmicutes,3VQTU@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YHH1_k127_5168972_0	765420.OSCT_2615	0.0	1213.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi,37711@32061|Chloroflexia	32061|Chloroflexia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
YHH1_k127_5168972_20	1123392.AQWL01000010_gene2295	9.787e-05	45.0	2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,2VY3B@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5168972_7	478741.JAFS01000002_gene538	1.55e-140	454.0	COG1063@1|root,COG1063@2|Bacteria,46SZR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YHH1_k127_5168972_19	595494.Tola_1999	2.906e-09	61.0	2DN0A@1|root,32UPR@2|Bacteria,1N1BR@1224|Proteobacteria,1S9NG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5168972_18	1047013.AQSP01000138_gene1065	3.152e-10	72.0	COG1503@1|root,COG1503@2|Bacteria,2NQ54@2323|unclassified Bacteria	2|Bacteria	J	translation release factor activity	yocB	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
YHH1_k127_5168972_17	1121022.ABENE_17980	4.491e-12	70.0	COG3809@1|root,COG3809@2|Bacteria,1N6ZY@1224|Proteobacteria,2UFVY@28211|Alphaproteobacteria,2KHBV@204458|Caulobacterales	204458|Caulobacterales	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
YHH1_k127_5168972_16	1320556.AVBP01000002_gene4107	8.735e-18	89.0	COG1544@1|root,COG1544@2|Bacteria,1N8CQ@1224|Proteobacteria	1224|Proteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
YHH1_k127_5168972_10	502025.Hoch_2991	8.996e-106	355.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,42UN5@68525|delta/epsilon subdivisions,2WQU9@28221|Deltaproteobacteria,2YXHW@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
YHH1_k127_5168972_21	279714.FuraDRAFT_3686	0.0001461	47.0	2BNSJ@1|root,32HG4@2|Bacteria,1MV5R@1224|Proteobacteria,2VR61@28216|Betaproteobacteria,2KSW6@206351|Neisseriales	206351|Neisseriales	S	Domain of unknown function (DUF4337)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4337
YHH1_k127_5168972_8	279714.FuraDRAFT_2213	8.758e-128	415.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2VJH3@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
YHH1_k127_5168972_5	1121920.AUAU01000004_gene859	3.066e-204	642.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria	57723|Acidobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH1_k127_5168972_9	1121920.AUAU01000004_gene858	1.651e-123	402.0	COG0119@1|root,COG0119@2|Bacteria,3Y2NJ@57723|Acidobacteria	57723|Acidobacteria	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
YHH1_k127_5168972_4	1121920.AUAU01000004_gene857	3.075e-209	655.0	COG1804@1|root,COG1804@2|Bacteria,3Y4ZM@57723|Acidobacteria	57723|Acidobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
YHH1_k127_5168972_2	1121920.AUAU01000004_gene856	3.96e-217	681.0	COG0065@1|root,COG0065@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	hacA	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
YHH1_k127_5168972_12	1121920.AUAU01000004_gene855	1.933e-66	233.0	COG0066@1|root,COG0066@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
YHH1_k127_5168972_13	1131730.BAVI_05739	7.926e-63	222.0	COG4671@1|root,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
YHH1_k127_5177411_0	760142.Hipma_1670	1.458e-141	460.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2M6Y2@213113|Desulfurellales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
YHH1_k127_5177411_3	267608.RSc0784	2.853e-40	167.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,1K7PD@119060|Burkholderiaceae	28216|Betaproteobacteria	G	peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
YHH1_k127_5177411_2	1120792.JAFV01000001_gene3701	5.737e-48	177.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VF0E@28211|Alphaproteobacteria,36YFG@31993|Methylocystaceae	28211|Alphaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	MA20_44950	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,Rhodanese
YHH1_k127_5183225_2	246194.CHY_0588	7.178e-86	301.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,249RZ@186801|Clostridia,42F15@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
YHH1_k127_5183225_5	1450694.BTS2_2108	4.695e-27	117.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1ZCZ4@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_5183225_9	552398.HMPREF0866_02380	0.0006604	49.0	COG5662@1|root,COG5662@2|Bacteria,1VKS6@1239|Firmicutes,24VD1@186801|Clostridia,3WM8H@541000|Ruminococcaceae	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
YHH1_k127_5183225_1	760568.Desku_1902	1.556e-146	473.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
YHH1_k127_5183225_3	1121377.KB906399_gene1741	4.91e-47	178.0	COG0274@1|root,COG0274@2|Bacteria,1WI7Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
YHH1_k127_5183225_6	595460.RRSWK_06911	3.325e-12	68.0	2EPX9@1|root,33HHS@2|Bacteria,2J4DJ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5183225_4	1379698.RBG1_1C00001G1047	6.778e-47	177.0	COG1913@1|root,COG1913@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
YHH1_k127_5183225_0	1379698.RBG1_1C00001G1048	3.97e-312	973.0	COG1205@1|root,COG1205@2|Bacteria,2NNKJ@2323|unclassified Bacteria	2|Bacteria	L	Domain of unknown function (DUF1998)	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
YHH1_k127_5183467_6	1379698.RBG1_1C00001G1245	3.07e-43	177.0	COG1629@1|root,COG4771@2|Bacteria,2NRGW@2323|unclassified Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YHH1_k127_5183467_9	1005395.CSV86_14109	2.492e-05	57.0	COG1629@1|root,COG4771@2|Bacteria,1QTS8@1224|Proteobacteria,1T1FF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Outer membrane receptor proteins mostly Fe transport	irp	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YHH1_k127_5183467_4	373903.Hore_15740	1.04e-50	186.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,3WANC@53433|Halanaerobiales	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
YHH1_k127_5183467_2	1379698.RBG1_1C00001G1242	4.781e-102	348.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22,MFS_1
YHH1_k127_5183467_1	1379698.RBG1_1C00001G1241	6.082e-110	366.0	COG0613@1|root,COG0613@2|Bacteria,2NPWD@2323|unclassified Bacteria	2|Bacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
YHH1_k127_5183467_3	1379698.RBG1_1C00001G1051	2.475e-75	256.0	COG0377@1|root,COG0377@2|Bacteria,2NP84@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YHH1_k127_5183467_7	1128421.JAGA01000002_gene139	3.295e-39	153.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
YHH1_k127_5183467_0	1379698.RBG1_1C00001G1053	5.541e-171	544.0	COG0649@1|root,COG0649@2|Bacteria,2NNWG@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
YHH1_k127_5183467_5	1379698.RBG1_1C00001G1054	1.264e-45	169.0	COG1905@1|root,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria	2|Bacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YHH1_k127_5183467_8	760192.Halhy_0321	1.21e-16	84.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
YHH1_k127_5200193_1	945713.IALB_1170	1.005e-106	377.0	2E09V@1|root,32VXB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5200193_0	880073.Calab_2072	2.119e-123	431.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH1_k127_5200193_3	880073.Calab_0077	4.253e-19	96.0	COG0558@1|root,COG0558@2|Bacteria,2NQ32@2323|unclassified Bacteria	2|Bacteria	I	CDP-alcohol phosphatidyltransferase	pgsA	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YHH1_k127_5200193_2	1120973.AQXL01000097_gene902	1.105e-82	289.0	COG3616@1|root,COG3616@2|Bacteria,1TSES@1239|Firmicutes,4HA93@91061|Bacilli,278J8@186823|Alicyclobacillaceae	91061|Bacilli	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
YHH1_k127_5200193_4	1158146.KB907121_gene1092	3.068e-08	66.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,1S4SH@1236|Gammaproteobacteria,1WZF6@135613|Chromatiales	135613|Chromatiales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH1_k127_5214548_2	864051.BurJ1DRAFT_1863	2.189e-27	111.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
YHH1_k127_5214548_1	765911.Thivi_3972	3.737e-30	120.0	COG1598@1|root,COG1598@2|Bacteria,1NBIX@1224|Proteobacteria,1SCV3@1236|Gammaproteobacteria,1WZ6M@135613|Chromatiales	135613|Chromatiales	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
YHH1_k127_5214548_3	1454004.AW11_01909	0.0001254	46.0	2DFFT@1|root,2ZRPJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5214548_0	1132855.KB913035_gene1951	2.71e-226	704.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2VKD6@28216|Betaproteobacteria,2KNE8@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
YHH1_k127_5220681_3	207559.Dde_2501	2.004e-20	93.0	2E3NW@1|root,32YM0@2|Bacteria,1NHVU@1224|Proteobacteria,431Y0@68525|delta/epsilon subdivisions,2WWVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5220681_4	255470.cbdbB7	1.445e-17	93.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
YHH1_k127_5220681_2	743299.Acife_0675	1.403e-45	170.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,2NDMP@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
YHH1_k127_5220681_0	552811.Dehly_1614	7.771e-187	589.0	COG0530@1|root,COG0530@2|Bacteria,2G6GV@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
YHH1_k127_5220681_1	1121405.dsmv_2689	1.079e-163	518.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,2MMNY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
YHH1_k127_5234439_0	234267.Acid_2554	6.41e-153	494.0	COG3344@1|root,COG3344@2|Bacteria	2|Bacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
YHH1_k127_5236916_0	926569.ANT_00510	4.29e-76	261.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
YHH1_k127_5236916_2	926569.ANT_06250	6.442e-58	205.0	COG1468@1|root,COG1468@2|Bacteria,2G6VA@200795|Chloroflexi	200795|Chloroflexi	L	Domain of unknown function DUF83	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
YHH1_k127_5236916_1	1227360.C176_00815	2.562e-58	209.0	COG1413@1|root,COG1413@2|Bacteria,1VTQX@1239|Firmicutes,4HTH7@91061|Bacilli	91061|Bacilli	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5240157_1	1031288.AXAA01000002_gene1383	1.528e-104	350.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,36EGP@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the acetokinase family	buk	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
YHH1_k127_5240157_2	1121405.dsmv_2840	8.599e-51	186.0	COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,42SK4@68525|delta/epsilon subdivisions,2WPI8@28221|Deltaproteobacteria,2MNKA@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	iorB-1	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
YHH1_k127_5240157_0	868595.Desca_2668	2.874e-139	456.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,260MU@186807|Peptococcaceae	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
YHH1_k127_5241900_0	1163617.SCD_n01864	2.224e-74	251.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
YHH1_k127_5243458_5	1460634.JCM19037_1934	3.588e-05	48.0	COG2808@1|root,COG2808@2|Bacteria,1UYCC@1239|Firmicutes,4HDSJ@91061|Bacilli	91061|Bacilli	K	Putative FMN-binding domain	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
YHH1_k127_5243458_4	1121875.KB907548_gene1644	2.514e-07	55.0	COG3832@1|root,COG3832@2|Bacteria,4NRDQ@976|Bacteroidetes,1I3G0@117743|Flavobacteriia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YHH1_k127_5243458_1	1380390.JIAT01000010_gene4968	1.976e-39	150.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
YHH1_k127_5243458_3	945713.IALB_2584	6.05e-18	86.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
YHH1_k127_5243458_2	765698.Mesci_2998	8.488e-25	108.0	COG1786@1|root,COG1786@2|Bacteria,1N5DN@1224|Proteobacteria,2UGA7@28211|Alphaproteobacteria,43KBA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
YHH1_k127_5243458_0	1118054.CAGW01000081_gene2691	7.87e-127	418.0	COG1679@1|root,COG1786@1|root,COG1679@2|Bacteria,COG1786@2|Bacteria,1UJDG@1239|Firmicutes,4HTS5@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
YHH1_k127_526405_2	880073.Calab_1947	4.642e-17	87.0	COG2304@1|root,COG2304@2|Bacteria,2NPT8@2323|unclassified Bacteria	2|Bacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
YHH1_k127_526405_3	109871.XP_006675911.1	4.83e-05	56.0	KOG4225@1|root,KOG4225@2759|Eukaryota,38DGK@33154|Opisthokonta,3NVBF@4751|Fungi	4751|Fungi	T	NADPH oxidase regulator	-	-	-	-	-	-	-	-	-	-	-	-	PB1,TPR_1,TPR_2,TPR_8
YHH1_k127_526405_0	1379698.RBG1_1C00001G0649	2.213e-52	194.0	COG2045@1|root,COG2045@2|Bacteria,2NPF1@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the ComB family	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
YHH1_k127_526405_1	113355.CM001775_gene2853	1.253e-37	144.0	COG0404@1|root,COG0404@2|Bacteria,1G0GR@1117|Cyanobacteria	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YHH1_k127_5275272_1	1499967.BAYZ01000156_gene556	1.038e-70	246.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K20444	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
YHH1_k127_5275272_2	382464.ABSI01000006_gene803	2.846e-53	197.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,HEAT_2,TetR_C_7,TetR_N
YHH1_k127_5275272_0	926549.KI421517_gene2964	2.791e-167	543.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
YHH1_k127_5327782_0	292415.Tbd_1871	1.286e-80	269.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,1KRIS@119069|Hydrogenophilales	119069|Hydrogenophilales	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
YHH1_k127_5327782_1	1158182.KB905021_gene700	3.1e-42	171.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	ictB	-	-	ko:K02847,ko:K18814	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.1,9.B.67.4,9.B.67.5	-	-	Wzy_C
YHH1_k127_5327782_2	1056820.KB900681_gene2859	6.121e-11	64.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH1_k127_533115_4	880073.Calab_3333	4.638e-73	250.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_533115_3	880073.Calab_3331	6.698e-92	322.0	2919D@1|root,2ZNWG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_533115_1	880073.Calab_3330	3.015e-153	495.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,2NS2I@2323|unclassified Bacteria	2|Bacteria	O	Pyridine nucleotide-disulphide oxidoreductase	trxB_2	-	1.18.1.2,1.19.1.1,1.8.1.9	ko:K00384,ko:K21567	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_10,Pyr_redox_3
YHH1_k127_533115_6	1089550.ATTH01000001_gene1875	1.419e-14	86.0	COG1538@1|root,COG1538@2|Bacteria,4PEXC@976|Bacteroidetes,1FJST@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
YHH1_k127_533115_5	1379270.AUXF01000001_gene2702	1.721e-72	263.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
YHH1_k127_533115_0	1089550.ATTH01000001_gene2034	0.0	1115.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1FJVI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
YHH1_k127_533115_2	1232437.KL662038_gene2279	1.395e-94	321.0	COG0697@1|root,COG0697@2|Bacteria,1N3FA@1224|Proteobacteria,42RW0@68525|delta/epsilon subdivisions,2WNEH@28221|Deltaproteobacteria,2MMWS@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_5374834_1	1121374.KB891576_gene511	4.765e-16	78.0	28NHW@1|root,2ZBJG@2|Bacteria,1RBJB@1224|Proteobacteria,1S31B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5374834_0	485917.Phep_0529	8.425e-29	123.0	COG1651@1|root,COG1651@2|Bacteria,4NQ9P@976|Bacteroidetes,1ISGX@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YHH1_k127_5374834_2	1118153.MOY_00370	2.695e-12	69.0	COG0582@1|root,COG0582@2|Bacteria,1P1R9@1224|Proteobacteria,1RRV0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YHH1_k127_5408424_3	575609.HMPREF0629_00457	6.257e-23	102.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,22G08@1570339|Peptoniphilaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH1_k127_5408424_1	926564.KI911634_gene2959	1.223e-64	231.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4F3T5@85017|Promicromonosporaceae	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH1_k127_5408424_0	880073.Calab_2438	5.673e-272	852.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YHH1_k127_5408424_2	694431.DESACE_03770	1.301e-24	109.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2M76J@213113|Desulfurellales	28221|Deltaproteobacteria	O	CS domain	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YHH1_k127_5408424_4	1232410.KI421428_gene1078	4.381e-16	88.0	COG1413@1|root,COG1413@2|Bacteria,1NR1B@1224|Proteobacteria,42Z9K@68525|delta/epsilon subdivisions,2WUBX@28221|Deltaproteobacteria,43UJN@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
YHH1_k127_5418848_1	1379698.RBG1_1C00001G1194	2.412e-63	250.0	COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	3.2.1.91	ko:K14194,ko:K19668	ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CHU_C,DUF11,FlgD_ig,PKD,SdrD_B
YHH1_k127_5418848_0	1379698.RBG1_1C00001G1664	5.396e-95	321.0	COG1351@1|root,COG1351@2|Bacteria,2NPQ2@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
YHH1_k127_5418848_2	1123242.JH636435_gene2591	9.742e-49	181.0	COG2317@1|root,COG2317@2|Bacteria,2IXSU@203682|Planctomycetes	203682|Planctomycetes	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
YHH1_k127_543998_1	1049564.TevJSym_af00540	6.676e-139	451.0	COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,1SN0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YHH1_k127_543998_0	1049564.TevJSym_af00530	2.969e-161	528.0	28K74@1|root,2Z9VA@2|Bacteria,1R8MQ@1224|Proteobacteria,1SKKZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_543998_2	525897.Dbac_2205	7.005e-74	267.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria,2MATU@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Glycos_transf_2
YHH1_k127_5443202_0	1192034.CAP_8124	2.241e-252	799.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
YHH1_k127_5443202_1	373994.Riv7116_1807	2.972e-50	190.0	COG0596@1|root,COG0596@2|Bacteria,1GJMM@1117|Cyanobacteria,1HSGW@1161|Nostocales	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YHH1_k127_5448553_0	1408473.JHXO01000006_gene1103	5.238e-59	220.0	COG4826@1|root,COG4826@2|Bacteria,4NG1G@976|Bacteroidetes,2FR07@200643|Bacteroidia	976|Bacteroidetes	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
YHH1_k127_5470322_5	1123393.KB891316_gene1153	4.248e-39	148.0	COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,2W02N@28216|Betaproteobacteria,1KS5P@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_5470322_2	396588.Tgr7_2080	2.045e-99	340.0	COG3307@1|root,COG3307@2|Bacteria,1RBNE@1224|Proteobacteria,1S2PP@1236|Gammaproteobacteria,1X0ED@135613|Chromatiales	135613|Chromatiales	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH1_k127_5470322_4	488538.SAR116_0695	1.487e-51	197.0	COG0438@1|root,COG0438@2|Bacteria,1PCJT@1224|Proteobacteria,2U983@28211|Alphaproteobacteria,4BTFA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_5470322_1	582744.Msip34_1911	1.187e-102	344.0	COG0438@1|root,COG0438@2|Bacteria,1RKCN@1224|Proteobacteria	1224|Proteobacteria	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_5470322_3	86106.I862_01290	1.573e-79	271.0	28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,2TTZQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5470322_0	1158762.KB898040_gene1397	5.071e-107	357.0	28IIB@1|root,2Z8JE@2|Bacteria,1QIR3@1224|Proteobacteria	1224|Proteobacteria	S	Glycosyltransferase family 10 (fucosyltransferase) C-term	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_10
YHH1_k127_5470322_6	292415.Tbd_1871	5.274e-34	132.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,1KRIS@119069|Hydrogenophilales	119069|Hydrogenophilales	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
YHH1_k127_5474873_0	555088.DealDRAFT_1892	2.766e-99	341.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,42JRJ@68298|Syntrophomonadaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
YHH1_k127_5474873_1	929562.Emtol_2763	5.986e-34	141.0	COG0726@1|root,COG0726@2|Bacteria,4NKYS@976|Bacteroidetes,47NF6@768503|Cytophagia	976|Bacteroidetes	G	PFAM Polysaccharide deacetylase	pgdA	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
YHH1_k127_5474873_2	1089553.Tph_c04170	4.558e-19	89.0	COG1142@1|root,COG1142@2|Bacteria,1UHYS@1239|Firmicutes,24JZC@186801|Clostridia,42H3B@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_3,Fer4_4,Fer4_6,Fer4_9
YHH1_k127_5486552_2	935836.JAEL01000004_gene2528	3.758e-11	76.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4IQKZ@91061|Bacilli,1ZRKZ@1386|Bacillus	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
YHH1_k127_5486552_3	1488328.JMCL01000081_gene1068	3.494e-10	73.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K03769,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
YHH1_k127_5486552_0	1379698.RBG1_1C00001G1740	4.537e-127	426.0	COG3852@1|root,COG3852@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,PAS_9
YHH1_k127_5486552_1	1379698.RBG1_1C00001G1741	7.709e-63	218.0	COG1459@1|root,COG1459@2|Bacteria,2NP2J@2323|unclassified Bacteria	2|Bacteria	U	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH1_k127_5490819_1	247490.KSU1_C0842	1.835e-37	153.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Cofac_haem_bdg,PDZ_2,Peptidase_M1,Peptidase_M28
YHH1_k127_5490819_2	1340493.JNIF01000003_gene4350	2.089e-11	68.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria	57723|Acidobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YHH1_k127_5490819_0	1379698.RBG1_1C00001G0775	5.614e-46	178.0	COG0484@1|root,COG0484@2|Bacteria,2NQUM@2323|unclassified Bacteria	2|Bacteria	O	Class III cytochrome C family	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2
YHH1_k127_5504609_6	448385.sce0987	1.357e-14	81.0	COG1520@1|root,COG4932@1|root,COG5624@1|root,COG1520@2|Bacteria,COG4932@2|Bacteria,COG5624@2|Bacteria,1QUEG@1224|Proteobacteria,42YJZ@68525|delta/epsilon subdivisions,2WWPU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KM	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B,TGFb_propeptide
YHH1_k127_5504609_3	1171373.PACID_17540	5.178e-40	160.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
YHH1_k127_5504609_2	945713.IALB_3118	2.608e-44	187.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
YHH1_k127_5504609_4	880073.Calab_2081	1.825e-25	123.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
YHH1_k127_5504609_5	1379698.RBG1_1C00001G0428	3.755e-21	110.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	B_lectin,FlgD_ig,PQQ_2,PQQ_3,Pkinase,VCBS
YHH1_k127_5504609_1	1168065.DOK_17670	1.114e-49	181.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1J5YH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
YHH1_k127_5504609_0	867845.KI911784_gene362	6.021e-69	256.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8,SLH,fn3
YHH1_k127_5513868_0	515635.Dtur_1288	2.14e-56	218.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
YHH1_k127_5517396_2	497964.CfE428DRAFT_6305	1.717e-54	195.0	COG1129@1|root,COG1129@2|Bacteria,46SG6@74201|Verrucomicrobia	74201|Verrucomicrobia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
YHH1_k127_5517396_1	497964.CfE428DRAFT_6304	9.403e-129	425.0	COG1172@1|root,COG1172@2|Bacteria,46V1Z@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
YHH1_k127_5517396_0	661478.OP10G_0991	1.83e-293	936.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,F5_F8_type_C,Glyco_hydro_38,Glyco_hydro_38C
YHH1_k127_5535727_0	926561.KB900617_gene1952	2.567e-93	323.0	COG5373@1|root,COG5373@2|Bacteria,1UUGX@1239|Firmicutes,24EBQ@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
YHH1_k127_5535727_2	926561.KB900617_gene1952	4.542e-33	136.0	COG5373@1|root,COG5373@2|Bacteria,1UUGX@1239|Firmicutes,24EBQ@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
YHH1_k127_5535727_1	573061.Clocel_1063	7.36e-61	218.0	COG1082@1|root,COG1082@2|Bacteria,1VFCG@1239|Firmicutes,24D46@186801|Clostridia,36IYJ@31979|Clostridiaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH1_k127_5538828_0	1254432.SCE1572_31200	1.15e-100	341.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria,2YU4D@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_5538828_1	269084.syc2102_c	6.766e-66	235.0	COG4229@1|root,COG4229@2|Bacteria,1G59P@1117|Cyanobacteria,1H3Y4@1129|Synechococcus	1117|Cyanobacteria	F	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)	mtnC	-	3.1.3.77	ko:K09880	ko00270,ko01100,map00270,map01100	M00034	R07395	RC02779	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
YHH1_k127_5538828_2	1173264.KI913949_gene37	5.827e-62	215.0	COG1791@1|root,COG1791@2|Bacteria,1G274@1117|Cyanobacteria	1117|Cyanobacteria	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
YHH1_k127_5547658_1	604331.AUHY01000022_gene1521	1.247e-118	390.0	COG2317@1|root,COG2317@2|Bacteria,1WIBI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
YHH1_k127_5547658_2	1379698.RBG1_1C00001G1616	2.56e-91	332.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
YHH1_k127_5547658_0	1047013.AQSP01000106_gene1757	3.367e-185	588.0	COG4690@1|root,COG4690@2|Bacteria,2NQBZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
YHH1_k127_5548138_2	1128421.JAGA01000003_gene3544	1.016e-10	66.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YHH1_k127_5548138_3	383372.Rcas_1659	5.068e-05	54.0	COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia	32061|Chloroflexia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5548138_1	859657.RPSI07_mp1075	1.069e-20	105.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria,1K5QN@119060|Burkholderiaceae	28216|Betaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH1_k127_5548138_0	331678.Cphamn1_0864	2.034e-40	166.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23,HlyD_D4,YtkA
YHH1_k127_5548384_1	638303.Thal_0887	1.618e-27	115.0	COG1324@1|root,COG1324@2|Bacteria,2G58I@200783|Aquificae	200783|Aquificae	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
YHH1_k127_5548384_2	526222.Desal_1059	9.234e-22	99.0	COG0011@1|root,COG0011@2|Bacteria,1N2GU@1224|Proteobacteria,42UPF@68525|delta/epsilon subdivisions,2WR94@28221|Deltaproteobacteria,2MH4T@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
YHH1_k127_5548384_0	1379698.RBG1_1C00001G1453	4.421e-120	391.0	COG0112@1|root,COG0112@2|Bacteria,2NP28@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_3081,iIT341.HP0183	SHMT
YHH1_k127_5552662_1	765420.OSCT_1171	2.807e-118	387.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi,375B0@32061|Chloroflexia	32061|Chloroflexia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YHH1_k127_5552662_0	357808.RoseRS_4157	1.471e-125	408.0	COG0226@1|root,COG0226@2|Bacteria,2G6FH@200795|Chloroflexi,374S9@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like,PBP_like_2
YHH1_k127_5561695_0	768671.ThimaDRAFT_2015	8.489e-62	218.0	COG2343@1|root,COG2343@2|Bacteria,1RJ3M@1224|Proteobacteria,1RVCY@1236|Gammaproteobacteria,1WY8R@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
YHH1_k127_5561695_4	1031711.RSPO_c01695	5.426e-13	70.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,1K0AH@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the Nudix hydrolase family	nudC_1	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
YHH1_k127_5561695_2	1198232.CYCME_0513	2.588e-16	81.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,462B0@72273|Thiotrichales	72273|Thiotrichales	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
YHH1_k127_5561695_6	1122604.JONR01000020_gene519	4.215e-07	55.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,1X7CU@135614|Xanthomonadales	135614|Xanthomonadales	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
YHH1_k127_5561695_1	1123228.AUIH01000012_gene77	6.742e-34	136.0	COG3011@1|root,COG3011@2|Bacteria,1N08P@1224|Proteobacteria,1S8S3@1236|Gammaproteobacteria,1XKXA@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
YHH1_k127_5561695_7	1122137.AQXF01000005_gene990	5.872e-07	55.0	COG4242@1|root,COG4242@2|Bacteria,1R6CH@1224|Proteobacteria,2U8MQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	PQ	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
YHH1_k127_5561695_3	234267.Acid_4157	2.057e-15	81.0	2CM2H@1|root,32SDI@2|Bacteria,3Y5AH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
YHH1_k127_5581592_1	1499967.BAYZ01000019_gene6271	2.868e-83	283.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
YHH1_k127_5581592_0	1122917.KB899662_gene2323	7.639e-147	473.0	COG0654@1|root,COG0654@2|Bacteria,1UK1D@1239|Firmicutes,4IUS1@91061|Bacilli,277QI@186822|Paenibacillaceae	91061|Bacilli	CH	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
YHH1_k127_5619531_1	1177181.T9A_01208	1.741e-29	128.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,1XI47@135619|Oceanospirillales	135619|Oceanospirillales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YHH1_k127_5619531_2	639282.DEFDS_1416	2.708e-28	119.0	COG1917@1|root,COG1917@2|Bacteria,2GFVX@200930|Deferribacteres	200930|Deferribacteres	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YHH1_k127_5619531_0	1157490.EL26_03540	8.489e-80	274.0	COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,278WK@186823|Alicyclobacillaceae	91061|Bacilli	Q	Chalcone and stilbene synthases, N-terminal domain	bcsA	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
YHH1_k127_5630349_1	1265505.ATUG01000003_gene704	2.658e-57	212.0	COG1629@1|root,COG4771@2|Bacteria,1RKNG@1224|Proteobacteria,43DI3@68525|delta/epsilon subdivisions,2X6DF@28221|Deltaproteobacteria,2MNYI@213118|Desulfobacterales	68525|delta/epsilon subdivisions	P	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH1_k127_5630349_0	555779.Dthio_PD3802	3.148e-63	237.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YHH1_k127_5641240_0	686340.Metal_0248	1.449e-103	342.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,1S4UH@1236|Gammaproteobacteria,1XEJU@135618|Methylococcales	135618|Methylococcales	S	Mut7-C ubiquitin	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C,Ub-Mut7C
YHH1_k127_5641240_1	1121422.AUMW01000005_gene576	1.967e-84	286.0	COG0620@1|root,COG0620@2|Bacteria,1TQX4@1239|Firmicutes,24A5D@186801|Clostridia,260DR@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5716396_0	1452718.JBOY01000108_gene383	8.474e-20	105.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1S1S2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Signal transduction histidine kinase	-	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF_2,HATPase_c,HisKA,Pkinase,dCache_1
YHH1_k127_5735638_1	237368.SCABRO_02917	4.698e-07	52.0	COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH1_k127_5735638_0	1131553.JIBI01000009_gene1255	7.407e-74	265.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria,373E2@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
YHH1_k127_5753371_2	765911.Thivi_3849	8.9e-13	68.0	2ED2F@1|root,336ZC@2|Bacteria,1N758@1224|Proteobacteria,1SE5R@1236|Gammaproteobacteria,1X1HU@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH1_k127_5753371_1	1267535.KB906767_gene3700	1.595e-79	272.0	COG1484@1|root,COG1484@2|Bacteria,3Y4QK@57723|Acidobacteria,2JNWI@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
YHH1_k127_5753371_0	351348.Maqu_1299	7.917e-162	526.0	COG2771@1|root,COG4584@1|root,COG2771@2|Bacteria,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,46A5W@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_24,rve
YHH1_k127_5765632_4	1379698.RBG1_1C00001G0779	3.863e-80	279.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
YHH1_k127_5765632_1	671143.DAMO_0821	2.525e-124	409.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
YHH1_k127_5765632_5	1379698.RBG1_1C00001G0781	2.461e-39	152.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
YHH1_k127_5765632_0	1191523.MROS_2800	4.416e-224	702.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gluD	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
YHH1_k127_5765632_3	1500894.JQNN01000001_gene779	1.964e-87	310.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,2WBX4@28216|Betaproteobacteria,476MV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
YHH1_k127_5765632_2	880072.Desac_0678	1.313e-88	296.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,2MQXS@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
YHH1_k127_5787571_1	289376.THEYE_A0177	1.876e-30	134.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I
YHH1_k127_5787571_0	398767.Glov_1762	9.022e-102	349.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,1NTJT@1224|Proteobacteria,42NK8@68525|delta/epsilon subdivisions,2WIM0@28221|Deltaproteobacteria,43TCJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
YHH1_k127_5787571_2	1268237.G114_03903	7.75e-14	83.0	COG0457@1|root,COG0457@2|Bacteria,1P0WK@1224|Proteobacteria,1SU5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
YHH1_k127_5788252_4	1382304.JNIL01000001_gene2641	1.894e-44	166.0	COG0454@1|root,COG0454@2|Bacteria,1V6N8@1239|Firmicutes,4HITB@91061|Bacilli,27AE7@186823|Alicyclobacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
YHH1_k127_5788252_3	1385511.N783_10325	5.707e-56	204.0	COG4976@1|root,COG4976@2|Bacteria,1V582@1239|Firmicutes,4HI2P@91061|Bacilli	91061|Bacilli	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH1_k127_5788252_0	596152.DesU5LDRAFT_0535	1.713e-238	754.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2M85I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
YHH1_k127_5788252_1	96561.Dole_2121	4.319e-74	263.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria,2MI2C@213118|Desulfobacterales	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
YHH1_k127_5788252_5	525904.Tter_0388	7.941e-26	115.0	COG1853@1|root,COG1853@2|Bacteria,2NQ72@2323|unclassified Bacteria	2|Bacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
YHH1_k127_5788252_7	1288826.MSNKSG1_06828	1.943e-07	61.0	2B52F@1|root,31XVQ@2|Bacteria,1MYIZ@1224|Proteobacteria,1SPHQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,VPEP
YHH1_k127_5788252_6	439235.Dalk_0740	2.727e-24	110.0	COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,43B7H@68525|delta/epsilon subdivisions,2X6KX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Nuclease (SNase domain protein)	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding,SNase
YHH1_k127_5788252_2	1379698.RBG1_1C00001G1267	5.815e-58	217.0	COG0419@1|root,COG0419@2|Bacteria,2NPX7@2323|unclassified Bacteria	2|Bacteria	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SMC_N,SbcCD_C
YHH1_k127_5790066_4	1313304.CALK_1921	3.72e-116	387.0	COG0343@1|root,COG0343@2|Bacteria	2|Bacteria	F	queuine tRNA-ribosyltransferase activity	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
YHH1_k127_5790066_3	1087448.Eab7_0071	2.641e-131	433.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,3WEN9@539002|Bacillales incertae sedis	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
YHH1_k127_5790066_7	1379698.RBG1_1C00001G0979	1.069e-90	305.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YHH1_k127_5790066_8	1379698.RBG1_1C00001G0978	1.674e-67	238.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YHH1_k127_5790066_2	56780.SYN_00640	1.077e-132	438.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2MQ50@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
YHH1_k127_5790066_9	1379698.RBG1_1C00001G0976	6.58e-65	232.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	ung	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH1_k127_5790066_5	796606.BMMGA3_05860	7.713e-113	378.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1ZD3R@1386|Bacillus	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
YHH1_k127_5790066_14	880073.Calab_0883	1.587e-14	82.0	COG2922@1|root,COG2922@2|Bacteria	2|Bacteria	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
YHH1_k127_5790066_12	945713.IALB_1953	2.459e-18	93.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
YHH1_k127_5790066_17	1123073.KB899241_gene2108	1.511e-05	54.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales	135614|Xanthomonadales	Q	Lamin Tail Domain	nucH	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Calx-beta,Exo_endo_phos,LTD
YHH1_k127_5790066_16	572477.Alvin_0439	3.752e-12	78.0	COG2010@1|root,COG2010@2|Bacteria,1NDHN@1224|Proteobacteria,1S700@1236|Gammaproteobacteria,1WYGG@135613|Chromatiales	135613|Chromatiales	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
YHH1_k127_5790066_15	1191523.MROS_0656	1.143e-13	83.0	28P4Q@1|root,2ZBZV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5790066_0	1284352.AOIG01000023_gene760	1.627e-165	535.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,26QQJ@186822|Paenibacillaceae	91061|Bacilli	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
YHH1_k127_5790066_6	1379698.RBG1_1C00001G0971	3.409e-110	364.0	COG0152@1|root,COG0152@2|Bacteria,2NP0V@2323|unclassified Bacteria	2|Bacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945,ko:K03566	ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	SAICAR_synt
YHH1_k127_5790066_10	518766.Rmar_1872	1.02e-53	196.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1FITI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
YHH1_k127_5790066_1	589865.DaAHT2_1958	8.161e-163	526.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2MIIZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YHH1_k127_5790066_13	1313301.AUGC01000001_gene1691	2.198e-17	92.0	COG3047@1|root,COG3047@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943,OMP_b-brl,OMP_b-brl_2
YHH1_k127_5790066_11	240015.ACP_0849	9.403e-43	166.0	COG0702@1|root,COG0702@2|Bacteria,3Y644@57723|Acidobacteria,2JKJ0@204432|Acidobacteriia	204432|Acidobacteriia	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
YHH1_k127_5852555_5	1379698.RBG1_1C00001G1332	4.384e-06	53.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
YHH1_k127_5852555_1	1379698.RBG1_1C00001G1329	2.14e-46	187.0	COG2199@1|root,COG3706@2|Bacteria,2NPJ3@2323|unclassified Bacteria	2|Bacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF_2,GGDEF,PAS_4,PAS_9,PocR,Response_reg
YHH1_k127_5852555_3	247490.KSU1_C0424	1.445e-21	106.0	COG1596@1|root,COG1596@2|Bacteria,2J1I5@203682|Planctomycetes	203682|Planctomycetes	M	SLBB domain	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YHH1_k127_5852555_4	1123393.KB891333_gene2602	1.496e-09	70.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria	28216|Betaproteobacteria	O	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,SEC-C,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
YHH1_k127_5852555_2	880073.Calab_3531	2.923e-39	156.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
YHH1_k127_5852555_0	1283300.ATXB01000001_gene1495	1.962e-70	251.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,1XG6S@135618|Methylococcales	135618|Methylococcales	G	Domain of unknown function (DUF3473)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
YHH1_k127_5889573_3	1232410.KI421421_gene3316	5.482e-15	74.0	COG0607@1|root,COG0607@2|Bacteria,1RA3A@1224|Proteobacteria,42QNH@68525|delta/epsilon subdivisions,2WMPB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MauE,Rhodanese
YHH1_k127_5889573_2	1232410.KI421418_gene2164	1.456e-23	103.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria,43TIP@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
YHH1_k127_5889573_0	1232410.KI421415_gene3120	1.629e-108	362.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42R8Z@68525|delta/epsilon subdivisions,2WMXX@28221|Deltaproteobacteria,43SJ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
YHH1_k127_5889573_1	177437.HRM2_08140	2.688e-55	214.0	COG2202@1|root,COG2208@1|root,COG3290@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,COG3290@2|Bacteria,1RCHY@1224|Proteobacteria,42R1G@68525|delta/epsilon subdivisions,2WMR7@28221|Deltaproteobacteria,2MJNU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	rsbP	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS,PAS_3,PAS_9,SpoIIE
YHH1_k127_5889573_4	398767.Glov_0187	2.039e-10	64.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YHH1_k127_5899127_1	1123368.AUIS01000004_gene120	8.518e-62	220.0	COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2K7@1236|Gammaproteobacteria,2NDJ6@225057|Acidithiobacillales	1236|Gammaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd
YHH1_k127_5899127_0	323261.Noc_1756	1.948e-73	262.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T3Z7@1236|Gammaproteobacteria,1X2QD@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YHH1_k127_5899127_3	1123368.AUIS01000006_gene567	3.785e-47	173.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,1T3Z8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
YHH1_k127_5899127_2	1229172.JQFA01000004_gene1808	1.757e-51	200.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7TU@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF4118,EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
YHH1_k127_5904980_3	1408473.JHXO01000008_gene2626	1.881e-53	194.0	COG2249@1|root,COG2249@2|Bacteria,4NGF7@976|Bacteroidetes,2FP6B@200643|Bacteroidia	976|Bacteroidetes	S	Flavodoxin-like protein	kefF	-	-	ko:K11748	-	-	-	-	ko00000,ko02000	2.A.37.1.2	-	-	Flavodoxin_2
YHH1_k127_5904980_2	1237149.C900_02118	7.09e-95	320.0	COG1266@1|root,COG1266@2|Bacteria,4NVAP@976|Bacteroidetes,47SVF@768503|Cytophagia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
YHH1_k127_5904980_0	880072.Desac_1923	1.967e-140	448.0	COG2519@1|root,COG2519@2|Bacteria,1MXAK@1224|Proteobacteria,42NCI@68525|delta/epsilon subdivisions,2WJUH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YHH1_k127_5904980_1	398767.Glov_0439	8.932e-121	398.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH1_k127_5904980_6	933262.AXAM01000025_gene3419	1.574e-22	100.0	COG5304@1|root,COG5304@2|Bacteria,1NBCZ@1224|Proteobacteria,42UUQ@68525|delta/epsilon subdivisions,2WQGQ@28221|Deltaproteobacteria,2MKJQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5904980_4	243275.TDE_1788	4.693e-25	107.0	COG2929@1|root,COG2929@2|Bacteria,2J8ZM@203691|Spirochaetes	203691|Spirochaetes	S	similarity to OMNI NTL01RC0476	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5904980_5	237368.SCABRO_03055	8.831e-25	106.0	COG5304@1|root,COG5304@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin,CopG_antitoxin
YHH1_k127_5904980_7	909663.KI867150_gene499	9.04e-08	54.0	COG2929@1|root,COG2929@2|Bacteria,1N3AZ@1224|Proteobacteria,438DV@68525|delta/epsilon subdivisions,2WXRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH1_k127_5910124_2	457570.Nther_2188	5.084e-33	134.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
YHH1_k127_5910124_1	1237149.C900_05913	9.736e-68	243.0	COG4677@1|root,COG4704@1|root,COG5184@1|root,COG5492@1|root,COG4677@2|Bacteria,COG4704@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4PN9Q@976|Bacteroidetes,47Y9H@768503|Cytophagia	976|Bacteroidetes	DZ	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
YHH1_k127_5910124_0	1121468.AUBR01000018_gene2702	1.844e-73	254.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
YHH1_k127_5910692_2	443143.GM18_0333	1.886e-08	65.0	COG0457@1|root,COG0457@2|Bacteria	443143.GM18_0333|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5910692_0	1492922.GY26_05135	2.47e-34	138.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	GNaT family	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
YHH1_k127_5910692_1	589924.Ferp_2166	6.837e-15	76.0	COG0189@1|root,arCOG01589@2157|Archaea,2XT55@28890|Euryarchaeota,246V9@183980|Archaeoglobi	183980|Archaeoglobi	H	RimK-like ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	RimK
YHH1_k127_5911628_2	1121918.ARWE01000001_gene2959	3.656e-53	192.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42T0Q@68525|delta/epsilon subdivisions,2WUA0@28221|Deltaproteobacteria,43SZX@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF_2,GGDEF,Response_reg
YHH1_k127_5911628_0	269799.Gmet_2816	6.451e-129	439.0	COG1413@1|root,COG1413@2|Bacteria,1N5TU@1224|Proteobacteria,42UDF@68525|delta/epsilon subdivisions,2WQ3K@28221|Deltaproteobacteria,43TQ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
YHH1_k127_5911628_1	243231.GSU0699	9.96e-103	348.0	COG2206@1|root,COG2206@2|Bacteria,1RE2G@1224|Proteobacteria,42S6Z@68525|delta/epsilon subdivisions,2WNCP@28221|Deltaproteobacteria,43TC7@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cyclic diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	HD
YHH1_k127_5920916_0	861299.J421_4196	1.554e-152	486.0	COG0365@1|root,COG0365@2|Bacteria,1ZSUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YHH1_k127_5920916_2	1197130.BAFM01000003_gene743	8.629e-39	149.0	arCOG02998@1|root,arCOG02998@2157|Archaea,2XYZK@28890|Euryarchaeota,23WYX@183963|Halobacteria	183963|Halobacteria	S	COG0662 Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YHH1_k127_5920916_6	179408.Osc7112_1799	4.198e-13	72.0	COG1308@1|root,COG1308@2|Bacteria,1G83N@1117|Cyanobacteria,1HC9J@1150|Oscillatoriales	1117|Cyanobacteria	K	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
YHH1_k127_5920916_3	1206732.BAGD01000019_gene44	2.114e-31	130.0	COG1246@1|root,COG1246@2|Bacteria,2IP00@201174|Actinobacteria,4G1QY@85025|Nocardiaceae	201174|Actinobacteria	E	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH1_k127_5920916_1	246194.CHY_1350	2.88e-121	400.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	bcd2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin
YHH1_k127_5920916_5	82654.Pse7367_1525	1.465e-23	104.0	arCOG08935@1|root,32Z08@2|Bacteria,1GAUH@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5920916_4	1519464.HY22_00560	2.616e-27	126.0	COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Reprolysin_5
YHH1_k127_593894_3	338966.Ppro_0828	2.477e-22	96.0	2BVK0@1|root,32QXS@2|Bacteria,1RKSK@1224|Proteobacteria,42ZW3@68525|delta/epsilon subdivisions,2WVED@28221|Deltaproteobacteria,43UVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_593894_4	1232410.KI421412_gene441	0.0005876	47.0	COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
YHH1_k127_593894_1	756499.Desde_0680	6.324e-76	263.0	COG0330@1|root,COG0330@2|Bacteria,1UZJK@1239|Firmicutes,24IK1@186801|Clostridia,261BT@186807|Peptococcaceae	186801|Clostridia	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH1_k127_593894_0	56780.SYN_00872	0.0	1225.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2MQVC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Cation transporter/ATPase, N-terminus	ctpF	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
YHH1_k127_593894_2	1125863.JAFN01000001_gene2566	1.64e-38	151.0	COG0589@1|root,COG0589@2|Bacteria,1Q1NA@1224|Proteobacteria,437CW@68525|delta/epsilon subdivisions,2WUX1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YHH1_k127_594584_2	330214.NIDE2727	1.336e-63	226.0	COG1249@1|root,COG1249@2|Bacteria,3J0IM@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH1_k127_594584_8	211586.SO_4473	6.446e-05	52.0	COG3637@1|root,COG3637@2|Bacteria,1NBZC@1224|Proteobacteria,1SEIV@1236|Gammaproteobacteria,2QBWK@267890|Shewanellaceae	1236|Gammaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
YHH1_k127_594584_3	443143.GM18_2805	2.536e-52	190.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,1RG9R@1224|Proteobacteria,42S0C@68525|delta/epsilon subdivisions,2WNYP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix transcriptional regulator PuuR, cupin domain-containing	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
YHH1_k127_594584_5	1150474.JQJI01000023_gene777	2.073e-42	159.0	COG1586@1|root,COG1586@2|Bacteria,2GCWX@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
YHH1_k127_594584_1	1265507.KB899636_gene2552	7.531e-87	300.0	COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,1Y3PQ@135624|Aeromonadales	135624|Aeromonadales	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YHH1_k127_594584_0	643648.Slip_1551	5.734e-110	365.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,42KBI@68298|Syntrophomonadaceae	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
YHH1_k127_594584_4	237368.SCABRO_01729	9.184e-47	177.0	COG0518@1|root,COG0518@2|Bacteria,2J0QU@203682|Planctomycetes	203682|Planctomycetes	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
YHH1_k127_594584_6	207559.Dde_1175	3.173e-29	121.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MGUH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_594584_7	96561.Dole_1704	8.525e-20	104.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5951039_0	521674.Plim_1325	2.677e-225	723.0	COG0587@1|root,COG0587@2|Bacteria,2IWSE@203682|Planctomycetes	203682|Planctomycetes	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
YHH1_k127_5951039_3	203122.Sde_2070	5.882e-36	150.0	29QWA@1|root,30BWM@2|Bacteria,1REIR@1224|Proteobacteria,1S50N@1236|Gammaproteobacteria,468FT@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBM_11,VanZ
YHH1_k127_5951039_1	56780.SYN_00568	3.476e-105	373.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
YHH1_k127_5951039_2	986075.CathTA2_0103	2.458e-69	242.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli	91061|Bacilli	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
YHH1_k127_5951039_4	1408433.JHXV01000041_gene3590	8.449e-14	81.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,2PBW4@246874|Cryomorphaceae	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
YHH1_k127_5951039_5	1123376.AUIU01000014_gene707	0.0001293	53.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
YHH1_k127_5961009_4	338963.Pcar_1474	1.284e-17	86.0	COG0457@1|root,COG0457@2|Bacteria,1QY6N@1224|Proteobacteria,42XBU@68525|delta/epsilon subdivisions,2WT6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5961009_0	706587.Desti_4504	1.785e-46	174.0	COG0640@1|root,COG1669@1|root,COG0640@2|Bacteria,COG1669@2|Bacteria,1R18C@1224|Proteobacteria,43EID@68525|delta/epsilon subdivisions,2X8GT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5961009_2	1191523.MROS_0520	2.237e-24	119.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Porin_2
YHH1_k127_5961009_1	1047013.AQSP01000053_gene289	5.555e-42	168.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH1_k127_5961009_3	1121957.ATVL01000008_gene4553	2.32e-21	108.0	COG5295@1|root,COG5295@2|Bacteria,4NKG1@976|Bacteroidetes,47NK6@768503|Cytophagia	976|Bacteroidetes	MUW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
YHH1_k127_5977060_0	1379698.RBG1_1C00001G0317	1.692e-227	722.0	COG0143@1|root,COG0143@2|Bacteria,2NNTX@2323|unclassified Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
YHH1_k127_5977060_1	335543.Sfum_3626	4.09e-71	248.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2MQH5@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
YHH1_k127_5977060_3	236097.ADG881_2397	2.24e-49	188.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1XIZA@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YHH1_k127_5977060_2	861299.J421_3052	1.004e-70	252.0	COG0564@1|root,COG0564@2|Bacteria,1ZSXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH1_k127_5977060_4	251229.Chro_2803	5.285e-47	175.0	COG1846@1|root,COG1846@2|Bacteria,1G6XI@1117|Cyanobacteria	1117|Cyanobacteria	K	MarR family transcriptional	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
YHH1_k127_5977060_5	1379698.RBG1_1C00001G1230	1.377e-39	150.0	COG0180@1|root,COG0180@2|Bacteria,2NNQX@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class I (W and Y)	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH1_k127_5979684_1	1123393.KB891330_gene795	2.358e-46	177.0	COG0457@1|root,COG0457@2|Bacteria,1N588@1224|Proteobacteria,2VVEN@28216|Betaproteobacteria,1KS62@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5979684_0	1163617.SCD_n02970	2.006e-150	481.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VJVY@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_5987302_1	525897.Dbac_1189	2.933e-55	194.0	COG0668@1|root,COG2823@1|root,COG0668@2|Bacteria,COG2823@2|Bacteria,1MW1F@1224|Proteobacteria,42S36@68525|delta/epsilon subdivisions,2WNQZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	BON,MS_channel
YHH1_k127_5987302_0	525897.Dbac_1190	4.116e-208	655.0	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,42SPG@68525|delta/epsilon subdivisions,2WU4E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
YHH1_k127_5987302_2	938709.AUSH02000020_gene1995	2.21e-45	173.0	COG5295@1|root,COG5492@1|root,COG5295@2|Bacteria,COG5492@2|Bacteria,4NV9S@976|Bacteroidetes	976|Bacteroidetes	UW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5987302_4	298653.Franean1_3065	0.0002429	45.0	COG3415@1|root,COG3415@2|Bacteria,2I3BN@201174|Actinobacteria	201174|Actinobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
YHH1_k127_5992646_0	1379698.RBG1_1C00001G0988	5.528e-71	258.0	COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria	2|Bacteria	C	lyase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
YHH1_k127_5999477_0	1379698.RBG1_1C00001G0201	2.589e-136	443.0	COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria	2|Bacteria	O	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YHH1_k127_5999477_4	457570.Nther_2923	6.154e-18	89.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia	186801|Clostridia	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YHH1_k127_5999477_3	484770.UFO1_2322	1.227e-26	119.0	COG0739@1|root,COG0739@2|Bacteria,1TRWJ@1239|Firmicutes	1239|Firmicutes	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
YHH1_k127_5999477_2	521098.Aaci_2940	3.817e-69	244.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,27886@186823|Alicyclobacillaceae	91061|Bacilli	K	Belongs to the ParB family	spo0J	GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	HTH_3,KorB,ParBc
YHH1_k127_5999477_1	518766.Rmar_0452	9.932e-102	336.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1FJ0J@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Cellulose biosynthesis protein BcsQ	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YHH1_k127_5999477_5	469378.Ccur_14160	4.355e-10	67.0	COG0357@1|root,COG0357@2|Bacteria,2HUVU@201174|Actinobacteria,4CVTN@84998|Coriobacteriia	84998|Coriobacteriia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
YHH1_k127_5999768_1	1492922.GY26_12405	4.162e-20	99.0	COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,1RXZP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Multidrug transporter	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23
YHH1_k127_5999768_0	247633.GP2143_14561	3.17e-60	219.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH1_k127_6011898_0	215803.DB30_7958	1.71e-18	101.0	COG3391@1|root,COG3391@2|Bacteria,1P80Y@1224|Proteobacteria,43959@68525|delta/epsilon subdivisions,2X4BM@28221|Deltaproteobacteria,2YYPB@29|Myxococcales	1224|Proteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6011898_1	1122179.KB890422_gene2240	3.907e-12	80.0	COG2931@1|root,COG3227@1|root,COG3292@1|root,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3292@2|Bacteria,4NHTI@976|Bacteroidetes	976|Bacteroidetes	T	zinc metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	CUB,Pep_M12B_propep,Reprolysin_5
YHH1_k127_6022390_3	338969.Rfer_2335	3.573e-133	434.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2VI8J@28216|Betaproteobacteria,4AD4J@80864|Comamonadaceae	28216|Betaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
YHH1_k127_6022390_0	1232437.KL662025_gene929	5.715e-195	616.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42Q4I@68525|delta/epsilon subdivisions,2WKRP@28221|Deltaproteobacteria,2MHRB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
YHH1_k127_6022390_6	1201290.M902_2466	2.029e-49	188.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,42QVG@68525|delta/epsilon subdivisions,2WNKA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_6022390_2	290317.Cpha266_1855	5.487e-147	482.0	COG0265@1|root,COG0265@2|Bacteria,1FDIE@1090|Chlorobi	1090|Chlorobi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH1_k127_6022390_8	439235.Dalk_3039	0.000199	53.0	COG4571@1|root,COG4571@2|Bacteria,1P2JI@1224|Proteobacteria,431WH@68525|delta/epsilon subdivisions,2WWU2@28221|Deltaproteobacteria,2MNYX@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Omptin family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6022390_7	247490.KSU1_A0078	2.14e-36	143.0	COG0680@1|root,COG0680@2|Bacteria,2J190@203682|Planctomycetes	203682|Planctomycetes	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
YHH1_k127_6022390_1	247490.KSU1_A0077	6.252e-188	596.0	COG3259@1|root,COG3259@2|Bacteria,2IYS2@203682|Planctomycetes	203682|Planctomycetes	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
YHH1_k127_6022390_4	518766.Rmar_2589	1.515e-122	399.0	COG1941@1|root,COG1941@2|Bacteria	2|Bacteria	C	coenzyme F420 hydrogenase activity	hoxY	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
YHH1_k127_6022390_5	247490.KSU1_A0075	1.248e-113	371.0	COG0543@1|root,COG0543@2|Bacteria,2IYBB@203682|Planctomycetes	203682|Planctomycetes	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
YHH1_k127_6029287_0	1408428.JNJP01000122_gene1695	3.273e-176	567.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2M7VB@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
YHH1_k127_6029287_1	700598.Niako_6434	9.352e-110	376.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1ISM5@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
YHH1_k127_6029287_5	517418.Ctha_1463	6.678e-13	78.0	COG0457@1|root,COG0457@2|Bacteria,1FF81@1090|Chlorobi	1090|Chlorobi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6029287_3	290315.Clim_0132	7.955e-62	226.0	COG0701@1|root,COG0701@2|Bacteria,1FDFD@1090|Chlorobi	1090|Chlorobi	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
YHH1_k127_6029287_4	658088.HMPREF0987_01594	1.046e-30	131.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,27MSJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
YHH1_k127_6029287_2	1121129.KB903359_gene2140	3.56e-71	252.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,2FP3B@200643|Bacteroidia,22WQE@171551|Porphyromonadaceae	976|Bacteroidetes	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH1_k127_6029287_6	1379698.RBG1_1C00001G1343	9.629e-07	57.0	COG2199@1|root,COG2199@2|Bacteria,2NS3Z@2323|unclassified Bacteria	2|Bacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
YHH1_k127_6037808_1	1121937.AUHJ01000002_gene3583	1.123e-60	213.0	COG0500@1|root,COG0500@2|Bacteria,1MWPI@1224|Proteobacteria,1RPFG@1236|Gammaproteobacteria,465J1@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	VP0880	-	-	-	-	-	-	-	-	-	-	-	HNH_4,Methyltransf_11,Methyltransf_23,Methyltransf_25
YHH1_k127_6037808_2	365044.Pnap_3948	1.423e-38	148.0	COG1669@1|root,COG1669@2|Bacteria,1N5A8@1224|Proteobacteria,2VXZ7@28216|Betaproteobacteria,4AID9@80864|Comamonadaceae	28216|Betaproteobacteria	L	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
YHH1_k127_6037808_5	1249627.D779_2951	2.32e-12	67.0	COG2361@1|root,COG2361@2|Bacteria,1PTAK@1224|Proteobacteria,1S7VC@1236|Gammaproteobacteria,1WYQT@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
YHH1_k127_6037808_4	314285.KT71_02417	3.142e-16	79.0	COG0500@1|root,COG0500@2|Bacteria,1MWPI@1224|Proteobacteria,1RPFG@1236|Gammaproteobacteria,1JASA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Tellurite resistance protein TehB	VP0880	-	-	-	-	-	-	-	-	-	-	-	HNH_4,Methyltransf_11,Methyltransf_23,Methyltransf_25
YHH1_k127_6037808_3	998674.ATTE01000001_gene3030	1.646e-17	89.0	COG4849@1|root,COG4849@2|Bacteria,1RDHG@1224|Proteobacteria,1S125@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH1_k127_6037808_0	1123393.KB891326_gene21	7.073e-66	226.0	COG2426@1|root,COG2426@2|Bacteria,1N9Q5@1224|Proteobacteria	1224|Proteobacteria	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
YHH1_k127_6046694_2	765913.ThidrDRAFT_2193	2.491e-14	84.0	COG0823@1|root,COG1361@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,1R1T9@1224|Proteobacteria,1T5A3@1236|Gammaproteobacteria,1X2VR@135613|Chromatiales	135613|Chromatiales	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6046694_1	303518.XP_005742809.1	6.797e-17	96.0	2CMRF@1|root,2QRK8@2759|Eukaryota,38BZ6@33154|Opisthokonta,3BC6D@33208|Metazoa,3CRA6@33213|Bilateria,4834K@7711|Chordata,49FDS@7742|Vertebrata,4A5NH@7898|Actinopterygii	33208|Metazoa	T	Thrombospondin 1	THBS1	GO:0000187,GO:0000302,GO:0001501,GO:0001525,GO:0001568,GO:0001666,GO:0001786,GO:0001817,GO:0001818,GO:0001819,GO:0001932,GO:0001934,GO:0001936,GO:0001937,GO:0001944,GO:0001952,GO:0001953,GO:0001968,GO:0002040,GO:0002376,GO:0002544,GO:0002576,GO:0002577,GO:0002578,GO:0002580,GO:0002581,GO:0002604,GO:0002605,GO:0002682,GO:0002683,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0002694,GO:0002696,GO:0003007,GO:0003151,GO:0003197,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005543,GO:0005575,GO:0005576,GO:0005577,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005886,GO:0006417,GO:0006464,GO:0006807,GO:0006810,GO:0006887,GO:0006897,GO:0006909,GO:0006911,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006979,GO:0007049,GO:0007050,GO:0007155,GO:0007162,GO:0007275,GO:0007507,GO:0007610,GO:0008150,GO:0008152,GO:0008201,GO:0008284,GO:0008285,GO:0008289,GO:0009266,GO:0009408,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009897,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010324,GO:0010466,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010594,GO:0010595,GO:0010596,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010632,GO:0010633,GO:0010634,GO:0010646,GO:0010647,GO:0010648,GO:0010746,GO:0010748,GO:0010749,GO:0010751,GO:0010752,GO:0010754,GO:0010755,GO:0010757,GO:0010758,GO:0010759,GO:0010762,GO:0010763,GO:0010810,GO:0010811,GO:0010812,GO:0010941,GO:0010942,GO:0010951,GO:0010955,GO:0012505,GO:0014070,GO:0016020,GO:0016043,GO:0016192,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0017015,GO:0017134,GO:0018149,GO:0019220,GO:0019222,GO:0019538,GO:0019838,GO:0019955,GO:0022402,GO:0022603,GO:0022610,GO:0023051,GO:0023056,GO:0023057,GO:0030141,GO:0030155,GO:0030162,GO:0030169,GO:0030193,GO:0030194,GO:0030198,GO:0030334,GO:0030335,GO:0030336,GO:0030511,GO:0031012,GO:0031091,GO:0031093,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031401,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032026,GO:0032101,GO:0032102,GO:0032103,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032368,GO:0032369,GO:0032501,GO:0032502,GO:0032570,GO:0032655,GO:0032680,GO:0032695,GO:0032760,GO:0032879,GO:0032890,GO:0032891,GO:0032908,GO:0032914,GO:0032940,GO:0032991,GO:0033554,GO:0033555,GO:0033674,GO:0033993,GO:0034248,GO:0034250,GO:0034284,GO:0034599,GO:0034605,GO:0034614,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0034774,GO:0034976,GO:0035239,GO:0035265,GO:0035295,GO:0035690,GO:0036211,GO:0036293,GO:0040007,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0040036,GO:0040037,GO:0042035,GO:0042108,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042534,GO:0042535,GO:0042802,GO:0042981,GO:0043030,GO:0043032,GO:0043062,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043154,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043236,GO:0043269,GO:0043271,GO:0043277,GO:0043281,GO:0043394,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043535,GO:0043536,GO:0043537,GO:0043549,GO:0043652,GO:0044070,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045595,GO:0045637,GO:0045652,GO:0045727,GO:0045765,GO:0045766,GO:0045785,GO:0045786,GO:0045859,GO:0045860,GO:0045861,GO:0045937,GO:0046872,GO:0046903,GO:0048265,GO:0048266,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048646,GO:0048660,GO:0048661,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050431,GO:0050678,GO:0050680,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050818,GO:0050820,GO:0050839,GO:0050840,GO:0050865,GO:0050867,GO:0050878,GO:0050896,GO:0050920,GO:0050921,GO:0050922,GO:0051049,GO:0051051,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051271,GO:0051272,GO:0051336,GO:0051338,GO:0051346,GO:0051347,GO:0051592,GO:0051674,GO:0051716,GO:0051726,GO:0051893,GO:0051895,GO:0051896,GO:0051897,GO:0051917,GO:0051918,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060485,GO:0060548,GO:0061024,GO:0061041,GO:0061448,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070051,GO:0070052,GO:0070482,GO:0070613,GO:0070887,GO:0071241,GO:0071622,GO:0071634,GO:0071636,GO:0071675,GO:0071704,GO:0071731,GO:0071732,GO:0071813,GO:0071814,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072341,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090049,GO:0090051,GO:0090092,GO:0090100,GO:0090109,GO:0090287,GO:0090288,GO:0090303,GO:0097366,GO:0097367,GO:0097708,GO:0098552,GO:0098657,GO:0098868,GO:0099024,GO:0099503,GO:1900046,GO:1900048,GO:1901342,GO:1901343,GO:1901564,GO:1901654,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901888,GO:1901889,GO:1902041,GO:1902043,GO:1902170,GO:1902531,GO:1902532,GO:1902533,GO:1903034,GO:1903036,GO:1903317,GO:1903318,GO:1903391,GO:1903392,GO:1903555,GO:1903557,GO:1903587,GO:1903588,GO:1903670,GO:1903671,GO:1903706,GO:1903792,GO:1903844,GO:1903846,GO:1903959,GO:1903960,GO:1904018,GO:1904035,GO:1904037,GO:1905521,GO:1905523,GO:1905952,GO:1905953,GO:2000026,GO:2000112,GO:2000116,GO:2000117,GO:2000145,GO:2000146,GO:2000147,GO:2000181,GO:2000191,GO:2000192,GO:2000351,GO:2000353,GO:2000377,GO:2000379,GO:2001026,GO:2001027,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001237,GO:2001238	-	ko:K16857	ko04015,ko04115,ko04145,ko04151,ko04350,ko04510,ko04512,ko05144,ko05165,ko05205,ko05206,ko05219,map04015,map04115,map04145,map04151,map04350,map04510,map04512,map05144,map05165,map05205,map05206,map05219	-	-	-	ko00000,ko00001,ko00536,ko04131,ko04516	-	-	-	EGF_3,EGF_CA,Laminin_G_2,TSP_1,TSP_3,TSP_C,VWC,cEGF
YHH1_k127_6046694_0	1147.D082_25660	1.082e-45	190.0	COG2931@1|root,COG3204@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,1G5KY@1117|Cyanobacteria,1H6DE@1142|Synechocystis	1117|Cyanobacteria	QU	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,HemolysinCabind,VCBS
YHH1_k127_6046694_3	984262.SGRA_3562	7.264e-06	52.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1IYS6@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
YHH1_k127_6047520_2	1179773.BN6_26590	2.831e-26	116.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4E5MF@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
YHH1_k127_6047520_0	251221.35214536	1.633e-208	670.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1G4UJ@1117|Cyanobacteria	1117|Cyanobacteria	CO	Disulphide bond corrector protein DsbC	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YHH1_k127_6047520_1	945713.IALB_0515	3.231e-60	213.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH1_k127_6075517_3	1379698.RBG1_1C00001G1428	2.668e-48	189.0	COG2911@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NS5I@2323|unclassified Bacteria	2|Bacteria	U	FlgD Ig-like domain	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,FlgD_ig,PKD,SLH
YHH1_k127_6075517_0	713586.KB900536_gene50	0.0	1049.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
YHH1_k127_6075517_1	886293.Sinac_5855	0.0	1046.0	COG3280@1|root,COG3280@2|Bacteria,2IYFT@203682|Planctomycetes	203682|Planctomycetes	G	Alpha amylase, catalytic domain	-	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
YHH1_k127_6075517_2	713587.THITH_11270	3.346e-238	750.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1RP2N@1236|Gammaproteobacteria,1WWIM@135613|Chromatiales	135613|Chromatiales	G	TIGRFAM malto-oligosyltrehalose trehalohydrolase	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
YHH1_k127_6075517_4	1379698.RBG1_1C00001G0428	2.35e-26	119.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	B_lectin,FlgD_ig,PQQ_2,PQQ_3,Pkinase,VCBS
YHH1_k127_6075517_5	1340493.JNIF01000003_gene2186	1.25e-11	68.0	COG1026@1|root,COG1026@2|Bacteria	2|Bacteria	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
YHH1_k127_6112539_2	441769.ABFU01000051_gene3881	1.506e-05	47.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,4HKR7@91061|Bacilli,1ZHUY@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
YHH1_k127_6112539_1	1196323.ALKF01000173_gene59	2.258e-09	64.0	COG0791@1|root,COG0791@2|Bacteria,1V5H7@1239|Firmicutes,4HA49@91061|Bacilli	91061|Bacilli	M	Putative peptidoglycan binding domain	lytE	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,PG_binding_1
YHH1_k127_6112539_0	997346.HMPREF9374_3758	2.346e-28	119.0	COG1762@1|root,COG1762@2|Bacteria,1UK64@1239|Firmicutes,4ITII@91061|Bacilli	91061|Bacilli	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2
YHH1_k127_6132682_0	1499967.BAYZ01000040_gene2239	6.683e-48	187.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,HemolysinCabind
YHH1_k127_6132682_1	1123073.KB899241_gene2213	6.419e-16	90.0	COG1073@1|root,COG1073@2|Bacteria,1R34U@1224|Proteobacteria,1SYR4@1236|Gammaproteobacteria,1X4S6@135614|Xanthomonadales	135614|Xanthomonadales	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	-
YHH1_k127_6132682_2	203275.BFO_0222	2.72e-11	68.0	COG0793@1|root,COG0793@2|Bacteria,4NEFX@976|Bacteroidetes,2FU5X@200643|Bacteroidia,22YP3@171551|Porphyromonadaceae	976|Bacteroidetes	M	Peptidase family S41	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
YHH1_k127_6156673_1	240292.Ava_5030	1.332e-64	223.0	COG2267@1|root,COG2267@2|Bacteria,1G000@1117|Cyanobacteria,1HQSB@1161|Nostocales	1117|Cyanobacteria	I	Prolyl oligopeptidase family	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
YHH1_k127_6156673_2	1123393.KB891316_gene1574	4.363e-49	179.0	28RKB@1|root,2ZDZ5@2|Bacteria,1PAWP@1224|Proteobacteria,2WC7G@28216|Betaproteobacteria,1KT73@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6156673_0	1163617.SCD_n00707	1.084e-196	616.0	COG1361@1|root,COG1361@2|Bacteria,1R5HW@1224|Proteobacteria,2VZ99@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
YHH1_k127_6156673_4	1044.EH31_03120	1.265e-06	51.0	COG3647@1|root,COG3647@2|Bacteria,1RDTT@1224|Proteobacteria,2VGJQ@28211|Alphaproteobacteria,2KE4B@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
YHH1_k127_6156673_3	1304275.C41B8_18462	1.221e-18	87.0	2DBQY@1|root,2ZAHD@2|Bacteria,1QYTK@1224|Proteobacteria,1T3V2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
YHH1_k127_6167028_1	608538.HTH_0676	9.527e-33	134.0	COG1519@1|root,COG1519@2|Bacteria,2G46S@200783|Aquificae	200783|Aquificae	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
YHH1_k127_6167028_0	572479.Hprae_0253	1.57e-36	152.0	COG1663@1|root,COG1663@2|Bacteria,1TWGA@1239|Firmicutes,24HYU@186801|Clostridia,3WAME@53433|Halanaerobiales	186801|Clostridia	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
YHH1_k127_6167028_2	96561.Dole_1490	1.311e-26	112.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MIMB@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH1_k127_6171210_0	1283300.ATXB01000002_gene3078	5.814e-51	193.0	COG2202@1|root,COG2208@1|root,COG3290@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,1RGZF@1224|Proteobacteria,1S6GG@1236|Gammaproteobacteria,1XDM4@135618|Methylococcales	135618|Methylococcales	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9,SpoIIE
YHH1_k127_6171210_1	1191523.MROS_2238	2.303e-26	109.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	CBM_6,fn3
YHH1_k127_6203809_0	1379698.RBG1_1C00001G0159	4.421e-183	584.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_6203809_1	1379698.RBG1_1C00001G0158	3.154e-22	98.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
YHH1_k127_6205521_11	930166.CD58_14980	0.0007876	47.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria	1224|Proteobacteria	C	PFAM Cytochrome c, class I	nirM	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
YHH1_k127_6205521_6	357808.RoseRS_3838	3.223e-43	168.0	COG0454@1|root,COG0456@2|Bacteria,2G8C5@200795|Chloroflexi	200795|Chloroflexi	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
YHH1_k127_6205521_1	330779.Saci_1629	4.823e-66	230.0	COG1839@1|root,arCOG04298@2157|Archaea,2XQ7K@28889|Crenarchaeota	28889|Crenarchaeota	L	PFAM Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
YHH1_k127_6205521_5	1278073.MYSTI_05126	7.429e-50	200.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
YHH1_k127_6205521_8	1254432.SCE1572_25105	3.006e-11	75.0	2DP1D@1|root,3304P@2|Bacteria,1R5XI@1224|Proteobacteria,4386M@68525|delta/epsilon subdivisions,2X9ZN@28221|Deltaproteobacteria,2YVZY@29|Myxococcales	28221|Deltaproteobacteria	S	HmuY protein	-	-	-	-	-	-	-	-	-	-	-	-	HmuY
YHH1_k127_6205521_10	1227272.HMPREF1556_01576	0.000326	52.0	2DP1D@1|root,3304P@2|Bacteria,4NWC6@976|Bacteroidetes	976|Bacteroidetes	S	HmuY protein	-	-	-	-	-	-	-	-	-	-	-	-	HmuY
YHH1_k127_6205521_4	1120966.AUBU01000012_gene192	8.267e-64	245.0	COG4206@1|root,COG4206@2|Bacteria,4PKKN@976|Bacteroidetes,47YGD@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
YHH1_k127_6205521_0	1379698.RBG1_1C00001G0213	9.419e-82	282.0	COG0059@1|root,COG0059@2|Bacteria,2NNKS@2323|unclassified Bacteria	2|Bacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iHN637.CLJU_RS07505,iIT341.HP0330,iLF82_1304.LF82_1103	IlvC,IlvN
YHH1_k127_6205521_3	1379698.RBG1_1C00001G0181	3.892e-64	239.0	COG0157@1|root,COG0157@2|Bacteria,2NP3F@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the NadC ModD family	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988,iHN637.CLJU_RS12010,iLJ478.TM1645	QRPTase_C,QRPTase_N
YHH1_k127_6205521_2	1379698.RBG1_1C00001G0182	3.299e-65	234.0	COG0340@1|root,COG0340@2|Bacteria,2NPG2@2323|unclassified Bacteria	2|Bacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
YHH1_k127_6218409_18	66874.JOFS01000009_gene2849	2.281e-14	79.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Autotransporter,Peptidase_M10,Peptidase_S8,Peptidase_S8_N
YHH1_k127_6218409_21	504472.Slin_5755	0.0002104	55.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,47MSH@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM TonB-dependent siderophore receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_6218409_0	1223410.KN050846_gene2228	3.266e-213	689.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,1HZ6R@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor for Fe3 -dicitrate	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_6218409_7	675815.VOA_003442	5.822e-77	281.0	COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,1RPAU@1236|Gammaproteobacteria,1XV81@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF3413)	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	DUF3413,Sulfatase
YHH1_k127_6218409_14	926550.CLDAP_28780	7.529e-25	108.0	COG0724@1|root,COG0724@2|Bacteria,2G74A@200795|Chloroflexi	200795|Chloroflexi	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_6218409_1	929556.Solca_0522	2.476e-198	634.0	COG1032@1|root,COG1032@2|Bacteria,4PHMM@976|Bacteroidetes,1IWI2@117747|Sphingobacteriia	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6218409_22	368408.Tpen_1010	0.0003248	47.0	arCOG03714@1|root,arCOG03714@2157|Archaea,2XQDX@28889|Crenarchaeota	28889|Crenarchaeota	F	ATP cone domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone
YHH1_k127_6218409_20	1232410.KI421421_gene3263	4.89e-05	46.0	COG2846@1|root,COG2846@2|Bacteria,1MVCQ@1224|Proteobacteria,42NXK@68525|delta/epsilon subdivisions,2WMGN@28221|Deltaproteobacteria,43TBF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,ScdA_N
YHH1_k127_6218409_17	1232410.KI421421_gene3263	2.144e-21	95.0	COG2846@1|root,COG2846@2|Bacteria,1MVCQ@1224|Proteobacteria,42NXK@68525|delta/epsilon subdivisions,2WMGN@28221|Deltaproteobacteria,43TBF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,ScdA_N
YHH1_k127_6218409_2	1379698.RBG1_1C00001G0607	3.071e-155	520.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
YHH1_k127_6218409_6	1121920.AUAU01000035_gene2752	1.32e-86	303.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
YHH1_k127_6218409_8	404589.Anae109_2915	1.872e-72	248.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6218409_12	290397.Adeh_3047	3.827e-28	120.0	COG3576@1|root,COG3576@2|Bacteria,1PT74@1224|Proteobacteria,432EH@68525|delta/epsilon subdivisions,2WXW0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6218409_4	290397.Adeh_3048	8.648e-118	396.0	COG2203@1|root,COG3576@1|root,COG2203@2|Bacteria,COG3576@2|Bacteria,1PP8V@1224|Proteobacteria	1224|Proteobacteria	T	flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
YHH1_k127_6218409_11	1348114.OM33_21000	4.179e-46	179.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,2Q3UZ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	IQ	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH1_k127_6218409_9	991.IW20_20360	1.514e-71	251.0	COG1794@1|root,COG1794@2|Bacteria,4NM9B@976|Bacteroidetes,1I13P@117743|Flavobacteriia,2NSW3@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
YHH1_k127_6218409_15	1120960.ATXG01000003_gene2068	1.872e-23	111.0	COG1266@1|root,COG1266@2|Bacteria,2GMJ1@201174|Actinobacteria,4FSDW@85023|Microbacteriaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YHH1_k127_6218409_10	1183438.GKIL_0737	7.723e-55	210.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
YHH1_k127_6218409_5	485918.Cpin_4074	4.752e-103	342.0	COG2321@1|root,COG2321@2|Bacteria,4NDTZ@976|Bacteroidetes,1INUC@117747|Sphingobacteriia	976|Bacteroidetes	S	Neutral zinc metallopeptidase	ypfJ	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
YHH1_k127_6218409_13	358681.BBR47_33150	4.094e-28	125.0	COG3153@1|root,COG3153@2|Bacteria,1UIPH@1239|Firmicutes,4ISP0@91061|Bacilli,26VCF@186822|Paenibacillaceae	91061|Bacilli	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
YHH1_k127_6218409_16	1304866.K413DRAFT_0485	2.542e-22	105.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia,36FYE@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YHH1_k127_6218409_3	1177181.T9A_02206	2.565e-122	400.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1XHJ1@135619|Oceanospirillales	135619|Oceanospirillales	P	antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
YHH1_k127_6218409_19	1379698.RBG1_1C00001G0668	4.733e-05	48.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	DUF1566,Phenol_MetA_deg
YHH1_k127_622974_4	373903.Hore_10040	6.313e-20	98.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3WASJ@53433|Halanaerobiales	186801|Clostridia	H	PFAM Thiamin pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
YHH1_k127_622974_0	331113.SNE_A00740	4.511e-71	251.0	COG0837@1|root,COG0837@2|Bacteria,2JH4J@204428|Chlamydiae	204428|Chlamydiae	H	Glucokinase	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
YHH1_k127_622974_3	485913.Krac_11264	9.841e-39	154.0	COG0363@1|root,COG0363@2|Bacteria,2G6S0@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glucosamine galactosamine-6-phosphate isomerase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
YHH1_k127_622974_2	1191523.MROS_0019	2.046e-41	154.0	COG0393@1|root,COG0393@2|Bacteria	2|Bacteria	S	Putative heavy-metal-binding	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
YHH1_k127_6270627_12	408672.NBCG_00755	2.156e-28	117.0	COG3324@1|root,COG3324@2|Bacteria,2HUGD@201174|Actinobacteria,4DSW3@85009|Propionibacteriales	201174|Actinobacteria	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YHH1_k127_6270627_4	1121904.ARBP01000033_gene3215	3.456e-81	278.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,47KCE@768503|Cytophagia	976|Bacteroidetes	T	PFAM response regulator receiver	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_6270627_3	313606.M23134_07077	7.893e-82	294.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47MII@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
YHH1_k127_6270627_15	1094755.MCO_00781	3.653e-08	64.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,48T7N@772|Bartonellaceae	28211|Alphaproteobacteria	O	Trypsin	dop	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH1_k127_6270627_2	1047013.AQSP01000131_gene1819	7.919e-87	305.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,DUF4625,NPCBM_assoc,PEGA
YHH1_k127_6270627_1	1047013.AQSP01000134_gene1373	1.532e-88	300.0	COG1131@1|root,COG1131@2|Bacteria,2NR18@2323|unclassified Bacteria	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_6270627_5	1047013.AQSP01000134_gene1374	4.65e-70	256.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC_transp_aux
YHH1_k127_6270627_6	1047013.AQSP01000134_gene1374	6.692e-67	247.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC_transp_aux
YHH1_k127_6270627_0	404589.Anae109_1755	1.193e-125	419.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,43C89@68525|delta/epsilon subdivisions,2X7IN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH1_k127_6270627_13	96561.Dole_2318	3.206e-17	83.0	2DRFV@1|root,33BJD@2|Bacteria,1NM2T@1224|Proteobacteria,42WGX@68525|delta/epsilon subdivisions,2WR8G@28221|Deltaproteobacteria,2MNYV@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6270627_14	404380.Gbem_0454	1.861e-15	77.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,43VXN@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6270627_8	1185876.BN8_06390	7.198e-57	210.0	COG4694@1|root,COG4694@2|Bacteria,4PPR9@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6270627_7	221288.JH992901_gene4595	3.715e-63	227.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1JGV5@1189|Stigonemataceae	1117|Cyanobacteria	S	Virulence factor BrkB	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
YHH1_k127_6270627_10	1128421.JAGA01000003_gene2819	9.459e-36	147.0	COG5637@1|root,COG5637@2|Bacteria,2NRUC@2323|unclassified Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Polyketide_cyc
YHH1_k127_6270627_9	1197706.AKKK01000007_gene804	1.674e-45	168.0	COG1145@1|root,32SB1@2|Bacteria,2IJFQ@201174|Actinobacteria,1W9BP@1268|Micrococcaceae	201174|Actinobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
YHH1_k127_6270627_11	1123288.SOV_5c00100	9.546e-34	132.0	COG3285@1|root,COG3285@2|Bacteria,1TSAC@1239|Firmicutes,4H38E@909932|Negativicutes	909932|Negativicutes	L	DNA polymerase LigD, polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
YHH1_k127_6277433_1	880073.Calab_2422	1.195e-137	450.0	COG1449@1|root,COG1449@2|Bacteria,2NQNB@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
YHH1_k127_6277433_3	1379698.RBG1_1C00001G0556	8.556e-55	205.0	COG1463@1|root,COG1463@2|Bacteria,2NPXB@2323|unclassified Bacteria	2|Bacteria	Q	MlaD protein	ttg2C	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
YHH1_k127_6277433_2	509635.N824_14215	6.905e-66	236.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
YHH1_k127_6277433_4	1237149.C900_00817	5.37e-35	141.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,47S2U@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YHH1_k127_6277433_0	1379698.RBG1_1C00001G1656	5.634e-252	789.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH1_k127_6289012_2	994573.T472_0205120	2.318e-13	74.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1VIJZ@1239|Firmicutes	1239|Firmicutes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH1_k127_6289012_1	994573.T472_0205120	1.071e-17	88.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1VIJZ@1239|Firmicutes	1239|Firmicutes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH1_k127_6289012_0	935863.AWZR01000003_gene2838	9.363e-134	440.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1X9FM@135614|Xanthomonadales	135614|Xanthomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
YHH1_k127_6309039_0	237368.SCABRO_02315	2.764e-47	190.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,2J07E@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glycos_transf_2,Methyltransf_23,TPR_16,TPR_19,TPR_7,TPR_8
YHH1_k127_6309039_1	1408422.JHYF01000011_gene3490	3.195e-30	126.0	COG1699@1|root,COG1699@2|Bacteria,1VA6Y@1239|Firmicutes,24QXE@186801|Clostridia,36JMK@31979|Clostridiaceae	186801|Clostridia	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
YHH1_k127_6309039_2	509191.AEDB02000049_gene4379	4.342e-12	77.0	COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,248FN@186801|Clostridia,3WIZX@541000|Ruminococcaceae	186801|Clostridia	N	Bacterial flagellin N-terminal helical region	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
YHH1_k127_6317489_0	880073.Calab_2000	5.878e-108	359.0	COG0451@1|root,COG0451@2|Bacteria,2NNNX@2323|unclassified Bacteria	2|Bacteria	GM	NAD(P)H-binding	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH1_k127_6317489_1	1237149.C900_01254	1.671e-06	55.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,4NF1M@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Peptidase_S8_N
YHH1_k127_633684_1	1163617.SCD_n00414	7.869e-107	349.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
YHH1_k127_633684_3	1121035.AUCH01000006_gene639	5.213e-82	281.0	29PGQ@1|root,30AEV@2|Bacteria,1RD19@1224|Proteobacteria,2VJM5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LpoB
YHH1_k127_633684_2	292415.Tbd_2514	1.859e-86	289.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,2VNRD@28216|Betaproteobacteria	28216|Betaproteobacteria	M	membrane lipoprotein lipid attachment site	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
YHH1_k127_633684_4	292415.Tbd_2515	6.641e-39	149.0	COG5633@1|root,COG5633@2|Bacteria,1N0V9@1224|Proteobacteria,2VW5E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1425)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1425
YHH1_k127_633684_0	292415.Tbd_2516	1.433e-161	522.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,2VKU2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
YHH1_k127_633684_5	870187.Thini_3541	3.103e-27	113.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria,461IT@72273|Thiotrichales	72273|Thiotrichales	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2
YHH1_k127_6367452_0	1379698.RBG1_1C00001G1432	1.106e-98	344.0	COG1196@1|root,COG1196@2|Bacteria,2NNYZ@2323|unclassified Bacteria	2|Bacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529,ko:K19171	-	-	-	-	ko00000,ko02048,ko03036	-	-	-	SMC_N,SMC_hinge
YHH1_k127_6367452_1	1470591.BW41_03041	1.948e-13	81.0	COG1426@1|root,COG1426@2|Bacteria,1MYWX@1224|Proteobacteria,2U8C2@28211|Alphaproteobacteria,2K4QD@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
YHH1_k127_6367795_2	1379698.RBG1_1C00001G0632	7.648e-30	121.0	COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
YHH1_k127_6367795_1	926569.ANT_26780	1.043e-40	158.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH1_k127_6367795_0	1379698.RBG1_1C00001G1819	3.381e-90	320.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6367795_3	1379698.RBG1_1C00001G1819	8.576e-23	106.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_637783_0	1379698.RBG1_1C00001G1141	3.746e-123	417.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2NP1D@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase SLT domain	CP_0155	-	-	ko:K08307,ko:K12204	-	-	-	-	ko00000,ko01000,ko01011,ko02044	3.A.7.10.1,3.A.7.9.1	-	-	LysM,SLT,T4SS_TraI
YHH1_k127_637783_2	1379698.RBG1_1C00001G1142	8.026e-69	244.0	COG0616@1|root,COG0616@2|Bacteria,2NPIE@2323|unclassified Bacteria	2|Bacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
YHH1_k127_637783_4	1379698.RBG1_1C00001G1143	6.185e-39	147.0	COG0776@1|root,COG0776@2|Bacteria,2NPU6@2323|unclassified Bacteria	2|Bacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup_1	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH1_k127_637783_6	761193.Runsl_4607	0.0001268	44.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes,47T08@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_637783_3	1379698.RBG1_1C00001G0991	1.149e-58	229.0	COG2911@1|root,COG2931@1|root,COG4447@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4447@2|Bacteria,2NR5X@2323|unclassified Bacteria	2|Bacteria	Q	FlgD Ig-like domain	-	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_3,DUF1735,Laminin_G_3
YHH1_k127_637783_1	313606.M23134_07555	3.896e-71	257.0	295M7@1|root,2ZSYM@2|Bacteria,4NNH9@976|Bacteroidetes,47UGS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_637783_5	1183438.GKIL_2943	7.998e-16	85.0	COG3291@1|root,COG5640@1|root,COG3291@2|Bacteria,COG5640@2|Bacteria,1GR9W@1117|Cyanobacteria	2|Bacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,PKD,PPC,SBBP,TIG,Trypsin
YHH1_k127_6393023_0	1082931.KKY_707	8.296e-14	85.0	COG5283@1|root,COG5283@2|Bacteria,1R5FU@1224|Proteobacteria,2VFQ8@28211|Alphaproteobacteria,3N7TR@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6408218_10	28072.Nos7524_0700	9.009e-46	170.0	COG4405@1|root,COG4405@2|Bacteria,1GE0T@1117|Cyanobacteria	1117|Cyanobacteria	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
YHH1_k127_6408218_4	1379698.RBG1_1C00001G1080	5.364e-129	441.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
YHH1_k127_6408218_3	1379698.RBG1_1C00001G1080	5.611e-132	449.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
YHH1_k127_6408218_6	1232410.KI421424_gene1745	2.119e-111	377.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria,43UB1@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	TOBE domain	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
YHH1_k127_6408218_9	1232410.KI421424_gene1744	4.219e-94	317.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
YHH1_k127_6408218_8	1232410.KI421424_gene1743	9.487e-111	364.0	COG1175@1|root,COG1175@2|Bacteria,1PHH6@1224|Proteobacteria,43EXG@68525|delta/epsilon subdivisions,2X9ZU@28221|Deltaproteobacteria,43VD7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
YHH1_k127_6408218_1	161156.JQKW01000007_gene872	2.201e-152	492.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	ugpB	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
YHH1_k127_6408218_2	886379.AEWI01000018_gene1301	3.872e-132	466.0	COG2911@1|root,COG2911@2|Bacteria,4NSGX@976|Bacteroidetes,2FWBM@200643|Bacteroidia,3XJUG@558415|Marinilabiliaceae	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA,TamB
YHH1_k127_6408218_7	1168034.FH5T_03885	4.674e-111	382.0	COG4775@1|root,COG4775@2|Bacteria,4NR0H@976|Bacteroidetes,2FW6I@200643|Bacteroidia	976|Bacteroidetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YHH1_k127_6408218_0	1379698.RBG1_1C00001G1511	1.482e-207	655.0	COG0312@1|root,COG0312@2|Bacteria,2NPIS@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YHH1_k127_6408218_5	1379698.RBG1_1C00001G1510	5.42e-112	374.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YHH1_k127_6408875_1	1122217.KB899568_gene760	1.053e-31	139.0	COG4796@1|root,COG4796@2|Bacteria,1UK31@1239|Firmicutes,4H2BW@909932|Negativicutes	909932|Negativicutes	U	type II and III secretion system protein	pilQ	-	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin,Secretin_N
YHH1_k127_6408875_4	1379698.RBG1_1C00001G0236	1.481e-24	108.0	COG2259@1|root,COG2259@2|Bacteria,2NRSH@2323|unclassified Bacteria	2|Bacteria	S	PFAM Methylamine utilisation protein MauE	mauE	-	-	-	-	-	-	-	-	-	-	-	MauE
YHH1_k127_6408875_5	1379698.RBG1_1C00001G0235	7.423e-16	89.0	COG0607@1|root,COG0607@2|Bacteria,2NRY7@2323|unclassified Bacteria	2|Bacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH1_k127_6408875_2	404589.Anae109_3911	1.18e-30	130.0	COG0428@1|root,COG0428@2|Bacteria,1RF7H@1224|Proteobacteria,42Y2I@68525|delta/epsilon subdivisions,2WSUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
YHH1_k127_6408875_0	1379698.RBG1_1C00001G1318	1.301e-66	239.0	COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YHH1_k127_6408875_3	1379698.RBG1_1C00001G1319	1.088e-28	117.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_6412582_2	1125863.JAFN01000001_gene865	3.353e-27	124.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH1_k127_6412582_0	1379698.RBG1_1C00001G0553	3.802e-129	420.0	COG1493@1|root,COG1493@2|Bacteria,2NP5B@2323|unclassified Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
YHH1_k127_6412582_1	1379698.RBG1_1C00001G0706	6.118e-40	164.0	COG0760@1|root,COG0760@2|Bacteria,2NR9Y@2323|unclassified Bacteria	2|Bacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3,TPR_7
YHH1_k127_6419997_5	938293.CAJU020000013_gene1578	0.0001164	46.0	COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,24J9S@186801|Clostridia,22HGW@1570339|Peptoniphilaceae	186801|Clostridia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
YHH1_k127_6419997_1	1379698.RBG1_1C00001G1216	1.071e-89	306.0	COG0407@1|root,COG0407@2|Bacteria,2NPIC@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH1_k127_6419997_2	1196031.ALEG01000046_gene4509	1.124e-86	294.0	COG2043@1|root,COG2043@2|Bacteria,1TT5P@1239|Firmicutes,4HFED@91061|Bacilli,1ZAXA@1386|Bacillus	91061|Bacilli	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
YHH1_k127_6419997_0	1379698.RBG1_1C00001G1210	8.56e-173	554.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_6419997_4	1379698.RBG1_1C00001G1208	1.162e-31	128.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	mshB	-	-	ko:K02456,ko:K02650,ko:K10924,ko:K10925	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,Pilin,T2SSG
YHH1_k127_6419997_3	1379698.RBG1_1C00001G1208	5.004e-37	147.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	mshB	-	-	ko:K02456,ko:K02650,ko:K10924,ko:K10925	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,Pilin,T2SSG
YHH1_k127_6458856_2	941449.dsx2_1269	1.987e-10	65.0	COG1215@1|root,COG1215@2|Bacteria,1QVA7@1224|Proteobacteria,43BPE@68525|delta/epsilon subdivisions,2X7QG@28221|Deltaproteobacteria,2MHIC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_6458856_0	1121413.JMKT01000015_gene262	1.511e-72	264.0	COG2244@1|root,COG2244@2|Bacteria,1QZC3@1224|Proteobacteria,42U79@68525|delta/epsilon subdivisions,2WQ6Z@28221|Deltaproteobacteria,2MFJW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
YHH1_k127_6458856_1	1111479.AXAR01000007_gene888	9.438e-64	236.0	COG0438@1|root,COG0438@2|Bacteria,1V0G0@1239|Firmicutes,4HCG7@91061|Bacilli,27A3C@186823|Alicyclobacillaceae	91061|Bacilli	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_6468528_1	1121439.dsat_1282	1.198e-80	282.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,439Z2@68525|delta/epsilon subdivisions,2X1YW@28221|Deltaproteobacteria,2M834@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_6468528_3	945713.IALB_3120	2.074e-10	71.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,HATPase_c,PKD_3,Reg_prop
YHH1_k127_6468528_0	1280689.AUJC01000001_gene2531	4.691e-115	379.0	COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,251A8@186801|Clostridia,36UJ5@31979|Clostridiaceae	186801|Clostridia	M	NAD-dependent epimerase dehydratase	capI	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH1_k127_6468528_2	941449.dsx2_1171	4.721e-17	90.0	COG3307@1|root,COG3307@2|Bacteria,1QTKA@1224|Proteobacteria,42VD4@68525|delta/epsilon subdivisions,2WRBR@28221|Deltaproteobacteria,2MAIC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH1_k127_650058_0	330214.NIDE0362	2.462e-183	593.0	COG0445@1|root,COG0445@2|Bacteria,3J0E9@40117|Nitrospirae	40117|Nitrospirae	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
YHH1_k127_650058_10	404589.Anae109_2915	3.814e-46	173.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_650058_4	716544.wcw_1785	5.683e-94	324.0	COG0486@1|root,COG0486@2|Bacteria,2JFUE@204428|Chlamydiae	204428|Chlamydiae	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
YHH1_k127_650058_6	1379698.RBG1_1C00001G0260	5.852e-71	261.0	COG0706@1|root,COG0706@2|Bacteria,2NP6C@2323|unclassified Bacteria	2|Bacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
YHH1_k127_650058_12	246195.DNO_0950	2.074e-23	103.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
YHH1_k127_650058_16	331113.SNE_A18370	3.034e-06	53.0	COG0594@1|root,COG0594@2|Bacteria,2JGGJ@204428|Chlamydiae	204428|Chlamydiae	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
YHH1_k127_650058_14	867902.Ornrh_1923	1.179e-13	71.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1I50B@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
YHH1_k127_650058_11	1185876.BN8_05234	6.938e-45	169.0	COG2323@1|root,COG2323@2|Bacteria,4NR3N@976|Bacteroidetes,47QT3@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
YHH1_k127_650058_1	237368.SCABRO_00479	4.158e-111	374.0	COG0426@1|root,COG0426@2|Bacteria,2J2P2@203682|Planctomycetes	203682|Planctomycetes	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
YHH1_k127_650058_7	234267.Acid_0827	2.895e-69	244.0	COG1108@1|root,COG1108@2|Bacteria,3Y93X@57723|Acidobacteria	57723|Acidobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
YHH1_k127_650058_8	1379698.RBG1_1C00001G0108	2.476e-67	240.0	COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the bacterial solute-binding protein 9 family	znuA	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
YHH1_k127_650058_13	1313265.JNIE01000003_gene1301	1.782e-20	105.0	COG3746@1|root,COG3746@2|Bacteria,2G4NR@200783|Aquificae	200783|Aquificae	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_650058_17	394503.Ccel_0109	0.0005062	51.0	COG1073@1|root,COG1073@2|Bacteria,1VTQP@1239|Firmicutes,25CJT@186801|Clostridia,36WXB@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1749)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
YHH1_k127_650058_15	1379698.RBG1_1C00001G1820	1.036e-11	76.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH1_k127_650058_9	1379698.RBG1_1C00001G0581	3.208e-54	217.0	COG2911@1|root,COG2911@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cohesin,FlgD_ig,Peptidase_S74
YHH1_k127_650058_2	1379698.RBG1_1C00001G0582	2.457e-106	377.0	COG2911@1|root,COG2911@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cohesin,FlgD_ig,Peptidase_S74
YHH1_k127_650058_5	1379698.RBG1_1C00001G0583	8.485e-85	313.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cohesin,FlgD_ig,Peptidase_S74
YHH1_k127_650058_3	1379698.RBG1_1C00001G0584	1.747e-101	342.0	COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.4.24.40	ko:K01406,ko:K14274,ko:K20276,ko:K21449	ko00040,ko01503,ko02024,map00040,map01503,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL
YHH1_k127_6501589_1	1379698.RBG1_1C00001G0205	1.315e-93	319.0	COG0648@1|root,COG0648@2|Bacteria,2NNN3@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
YHH1_k127_6501589_3	945713.IALB_3126	6.262e-27	121.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	ina	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M6
YHH1_k127_6501589_0	479434.Sthe_1653	1.012e-161	522.0	COG1012@1|root,COG1012@2|Bacteria,2G5NY@200795|Chloroflexi,27XK3@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
YHH1_k127_6501589_6	768671.ThimaDRAFT_4290	8.19e-06	53.0	COG4967@1|root,COG4967@2|Bacteria,1RKWI@1224|Proteobacteria,1SEEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
YHH1_k127_6501589_5	1232437.KL662035_gene2774	9.441e-10	69.0	COG4966@1|root,COG4966@2|Bacteria,1N2NR@1224|Proteobacteria,42TRJ@68525|delta/epsilon subdivisions,2WQQ2@28221|Deltaproteobacteria,2MKHU@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	pilus assembly protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,PilW
YHH1_k127_6501589_2	1379270.AUXF01000004_gene3145	4.04e-37	159.0	COG4726@1|root,COG4726@2|Bacteria,1ZUS8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6501589_4	1121380.JNIW01000072_gene3574	1.515e-15	84.0	COG4726@1|root,COG4726@2|Bacteria	2|Bacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
YHH1_k127_6518778_3	323848.Nmul_A0590	5.895e-18	87.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,37239@32003|Nitrosomonadales	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
YHH1_k127_6518778_1	1379698.RBG1_1C00001G0643	8.468e-117	385.0	COG0462@1|root,COG0462@2|Bacteria,2NNP6@2323|unclassified Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
YHH1_k127_6518778_2	935845.JADQ01000053_gene3521	1.327e-46	179.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,26QMA@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.29	-	iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
YHH1_k127_6518778_0	344747.PM8797T_17839	0.0	1041.0	COG1048@1|root,COG1048@2|Bacteria,2IY29@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH1_k127_6523382_1	635013.TherJR_2028	4.547e-95	327.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YHH1_k127_6523382_0	880073.Calab_2684	3.654e-129	421.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
YHH1_k127_6524184_4	247490.KSU1_C0666	1.811e-07	53.0	COG3668@1|root,COG3668@2|Bacteria,2J1AW@203682|Planctomycetes	203682|Planctomycetes	S	Plasmid stabilization system	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
YHH1_k127_6524184_3	671143.DAMO_0603	5.181e-09	59.0	2C2YU@1|root,33M8J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6524184_1	1173028.ANKO01000124_gene2870	1.244e-18	88.0	COG2026@1|root,COG2026@2|Bacteria,1GAIF@1117|Cyanobacteria	1117|Cyanobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
YHH1_k127_6524184_2	203119.Cthe_1672	6.689e-14	79.0	2F69T@1|root,33YTH@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
YHH1_k127_6524184_0	1484460.JSWG01000003_gene798	8.767e-91	304.0	COG0702@1|root,COG0702@2|Bacteria,4NJB0@976|Bacteroidetes,1I0QM@117743|Flavobacteriia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
YHH1_k127_6530855_0	1379698.RBG1_1C00001G0150	2.247e-243	759.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
YHH1_k127_6530855_2	1379698.RBG1_1C00001G0152	2.033e-69	244.0	COG0224@1|root,COG0224@2|Bacteria,2NP76@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138	ATP-synt
YHH1_k127_6530855_1	1379698.RBG1_1C00001G0153	6.158e-235	733.0	COG0055@1|root,COG0055@2|Bacteria,2NNRB@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH1_k127_6530855_3	1379698.RBG1_1C00001G0155	7.351e-34	135.0	COG0355@1|root,COG0355@2|Bacteria,2NPSQ@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190	ATP-synt_DE,ATP-synt_DE_N
YHH1_k127_6530855_4	1379698.RBG1_1C00001G1830	4.619e-26	113.0	COG1399@1|root,COG1399@2|Bacteria,2NPVD@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1399	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
YHH1_k127_6541175_2	471855.Shel_01220	0.0001958	47.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
YHH1_k127_6541175_0	765420.OSCT_1252	3.365e-26	120.0	COG5662@1|root,COG5662@2|Bacteria,2GBKH@200795|Chloroflexi,3781H@32061|Chloroflexia	32061|Chloroflexia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
YHH1_k127_6541175_1	82654.Pse7367_3184	6.979e-05	53.0	COG1413@1|root,COG1413@2|Bacteria,1G233@1117|Cyanobacteria,1H7RE@1150|Oscillatoriales	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,Trypsin_2
YHH1_k127_6547802_0	401526.TcarDRAFT_1563	5.534e-157	514.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes	909932|Negativicutes	NU	Type II IV secretion system protein	epsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH1_k127_6547802_1	1349767.GJA_2113	1.509e-69	250.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VJ2Y@28216|Betaproteobacteria,473HH@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC3	-	-	ko:K02455,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
YHH1_k127_6547802_2	589865.DaAHT2_2389	5.757e-09	63.0	COG4969@1|root,COG4969@2|Bacteria,1QZMY@1224|Proteobacteria,43D4G@68525|delta/epsilon subdivisions,2X8B1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH1_k127_6547802_3	351348.Maqu_0760	7.554e-09	66.0	COG2165@1|root,COG2165@2|Bacteria,1N7HN@1224|Proteobacteria,1SDMJ@1236|Gammaproteobacteria,468IH@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	mshA	-	-	ko:K10924	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
YHH1_k127_6547802_4	237368.SCABRO_00692	0.0009086	50.0	COG4972@1|root,COG4972@2|Bacteria,2IWXB@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
YHH1_k127_6589339_3	880073.Calab_0626	2.503e-76	260.0	COG1250@1|root,COG1250@2|Bacteria,2NQAW@2323|unclassified Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd2	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
YHH1_k127_6589339_0	1191523.MROS_1926	2.662e-164	526.0	COG0282@1|root,COG0282@2|Bacteria	2|Bacteria	F	acetate kinase activity	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
YHH1_k127_6589339_5	873533.HMPREF0663_10287	7e-08	63.0	2FJRB@1|root,34BE7@2|Bacteria,4P5QR@976|Bacteroidetes,2FYTE@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6589339_1	1379698.RBG1_1C00001G1759	5.496e-102	338.0	COG0330@1|root,COG0330@2|Bacteria,2NNUC@2323|unclassified Bacteria	2|Bacteria	O	prohibitin homologues	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH1_k127_6589339_2	289376.THEYE_A0592	7.403e-99	340.0	COG1030@1|root,COG1030@2|Bacteria,3J0WF@40117|Nitrospirae	40117|Nitrospirae	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
YHH1_k127_6589339_4	525904.Tter_1214	5.03e-64	231.0	COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria	2|Bacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YHH1_k127_6590762_10	880073.Calab_0626	1.035e-36	143.0	COG1250@1|root,COG1250@2|Bacteria,2NQAW@2323|unclassified Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd2	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
YHH1_k127_6590762_12	1303518.CCALI_01566	0.0004192	53.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CarboxypepD_reg,DUF11,NPCBM_assoc,Peptidase_M66
YHH1_k127_6590762_8	497964.CfE428DRAFT_2964	3.622e-44	168.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
YHH1_k127_6590762_0	340177.Cag_0008	6.299e-111	370.0	COG0743@1|root,COG0743@2|Bacteria,1FD70@1090|Chlorobi	1090|Chlorobi	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
YHH1_k127_6590762_1	1379698.RBG1_1C00001G0410	2.45e-101	341.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
YHH1_k127_6590762_2	1379698.RBG1_1C00001G0425	9.124e-74	257.0	COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria	2|Bacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YHH1_k127_6590762_11	1379698.RBG1_1C00001G1104	3.645e-10	69.0	2B0A3@1|root,31SM2@2|Bacteria,2NRWJ@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YHH1_k127_6590762_7	1379698.RBG1_1C00001G0424	7.69e-46	172.0	COG1131@1|root,COG1131@2|Bacteria,2NPQ3@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	ccmA	-	3.6.3.41	ko:K01990,ko:K02193	ko02010,map02010	M00254,M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.107	-	-	ABC_tran
YHH1_k127_6590762_5	880073.Calab_2347	5.347e-51	189.0	COG2386@1|root,COG2386@2|Bacteria,2NPHG@2323|unclassified Bacteria	2|Bacteria	O	CcmB protein	ccmB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.41	ko:K02193,ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	iECO111_1330.ECO111_2936,iYL1228.KPN_02080	CcmB
YHH1_k127_6590762_6	1379698.RBG1_1C00001G0504	4.491e-47	173.0	COG0629@1|root,COG0629@2|Bacteria,2NPP5@2323|unclassified Bacteria	2|Bacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YHH1_k127_6590762_4	648996.Theam_0757	1.107e-63	227.0	COG0171@1|root,COG0171@2|Bacteria,2G425@200783|Aquificae	200783|Aquificae	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
YHH1_k127_6590762_3	580331.Thit_0092	9.411e-69	240.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,42F0X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YHH1_k127_6590762_9	1379698.RBG1_1C00001G0055	5.254e-43	167.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
YHH1_k127_66082_0	660470.Theba_1316	1.603e-274	872.0	COG0060@1|root,COG0060@2|Bacteria,2GC5I@200918|Thermotogae	200918|Thermotogae	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YHH1_k127_66082_3	1379698.RBG1_1C00001G0104	3.382e-43	162.0	COG1734@1|root,COG1734@2|Bacteria,2NPX2@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulator, TraR DksA family	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
YHH1_k127_66082_4	1379698.RBG1_1C00001G0105	7.508e-28	120.0	COG0597@1|root,COG0597@2|Bacteria,2NPU1@2323|unclassified Bacteria	2|Bacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
YHH1_k127_66082_2	502025.Hoch_1468	1.526e-87	299.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,42VPN@68525|delta/epsilon subdivisions,2WRK6@28221|Deltaproteobacteria,2Z1WG@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_66082_5	1267533.KB906735_gene4737	3.633e-20	98.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_66082_1	1121472.AQWN01000002_gene2278	1.074e-141	462.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,260F2@186807|Peptococcaceae	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YHH1_k127_6639516_3	941449.dsx2_1181	1.703e-68	247.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,2MG45@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_6639516_7	237368.SCABRO_02898	1.984e-17	96.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
YHH1_k127_6639516_5	1123508.JH636440_gene2192	3.638e-59	219.0	COG0726@1|root,COG0726@2|Bacteria,2J0S7@203682|Planctomycetes	203682|Planctomycetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
YHH1_k127_6639516_4	1121439.dsat_1281	6.873e-66	240.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T55@68525|delta/epsilon subdivisions,2WPW2@28221|Deltaproteobacteria,2MG3X@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_6639516_2	935863.AWZR01000003_gene2845	6.998e-73	260.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1X7Y9@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferases group 1	-	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
YHH1_k127_6639516_1	1307759.JOMJ01000004_gene2491	9.529e-111	376.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria,2MATU@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
YHH1_k127_6639516_0	289376.THEYE_A0998	6.552e-151	488.0	COG1004@1|root,COG1004@2|Bacteria,3J0EJ@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH1_k127_6639516_6	1129374.AJE_02976	1.421e-29	125.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,1S9D2@1236|Gammaproteobacteria,465JH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_6652448_0	234267.Acid_5940	4.713e-180	593.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YHH1_k127_6653002_4	684719.HIMB114_00008350	1.261e-32	143.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,4BPCV@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the peptidase S1C family	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
YHH1_k127_6653002_3	1242864.D187_003430	4.569e-46	176.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,42UAY@68525|delta/epsilon subdivisions,2X5BX@28221|Deltaproteobacteria,2YV3H@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
YHH1_k127_6653002_1	861299.J421_0909	2.049e-54	195.0	COG2940@1|root,COG2940@2|Bacteria,1ZTR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
YHH1_k127_6653002_0	1379698.RBG1_1C00001G0921	2.631e-68	236.0	COG2169@1|root,COG2169@2|Bacteria,2NRJ0@2323|unclassified Bacteria	2|Bacteria	K	Metal binding domain of Ada	adaA1	-	2.1.1.63,3.2.2.21	ko:K10778,ko:K13529,ko:K13530,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,Endonuclea_NS_2,HTH_18,HhH-GPD
YHH1_k127_6653002_2	1356852.N008_18745	2.672e-50	185.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,4NFYC@976|Bacteroidetes,47NQC@768503|Cytophagia	976|Bacteroidetes	FL	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
YHH1_k127_6653002_6	1192034.CAP_2480	1.126e-12	81.0	COG5164@1|root,COG5164@2|Bacteria,1N2FU@1224|Proteobacteria,42WNM@68525|delta/epsilon subdivisions,2WRNC@28221|Deltaproteobacteria,2YVNH@29|Myxococcales	28221|Deltaproteobacteria	K	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
YHH1_k127_6653002_5	1122179.KB890421_gene2565	1.932e-27	129.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,4PM4Q@976|Bacteroidetes	976|Bacteroidetes	UW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
YHH1_k127_667927_3	1031288.AXAA01000033_gene1339	1.755e-43	164.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,24AR8@186801|Clostridia,36E9B@31979|Clostridiaceae	186801|Clostridia	E	aminopeptidase	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
YHH1_k127_667927_4	1071073.KI530539_gene45	6.171e-29	124.0	COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,4HE7X@91061|Bacilli,1ZB95@1386|Bacillus	91061|Bacilli	S	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool	ppaX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH1_k127_667927_6	492774.JQMB01000001_gene5965	2.377e-05	55.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,4B6YV@82115|Rhizobiaceae	28211|Alphaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YHH1_k127_667927_0	1379698.RBG1_1C00001G1233	4.28e-166	542.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
YHH1_k127_667927_1	926561.KB900617_gene1296	2.005e-89	306.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3WA63@53433|Halanaerobiales	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
YHH1_k127_667927_5	1121355.KB903379_gene745	1.995e-06	50.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YHH1_k127_667927_2	395494.Galf_2689	7.115e-78	274.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,44UYU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
YHH1_k127_6689738_5	1191523.MROS_2370	1.299e-16	83.0	COG1008@1|root,COG1008@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
YHH1_k127_6689738_0	1449126.JQKL01000022_gene111	2.95e-168	553.0	COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,24A16@186801|Clostridia	186801|Clostridia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5	ndhF	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
YHH1_k127_6689738_2	671143.DAMO_2707	9.562e-30	121.0	COG0713@1|root,COG0713@2|Bacteria,2NQ6R@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YHH1_k127_6689738_4	1122947.FR7_0184	2.664e-24	111.0	COG0839@1|root,COG0839@2|Bacteria,1VAQI@1239|Firmicutes,4H4S3@909932|Negativicutes	909932|Negativicutes	C	NADH-ubiquinone plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YHH1_k127_6689738_3	292459.STH2772	2.242e-24	110.0	COG1143@1|root,COG1143@2|Bacteria,1VBXF@1239|Firmicutes,24MWM@186801|Clostridia	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
YHH1_k127_6689738_1	1123511.KB905842_gene1666	1.832e-60	213.0	COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,4H24V@909932|Negativicutes	909932|Negativicutes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH1_k127_6690818_1	1286631.X805_38170	9.663e-73	247.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,1KIWC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
YHH1_k127_6690818_0	1265502.KB905931_gene1680	1.086e-239	753.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2VHHD@28216|Betaproteobacteria,4ABNC@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	DctM
YHH1_k127_6709408_0	96561.Dole_1704	7.569e-06	58.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6716774_3	1379698.RBG1_1C00001G1158	1.342e-68	245.0	COG0196@1|root,COG0196@2|Bacteria,2NPCV@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K07011,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
YHH1_k127_6716774_5	1499967.BAYZ01000080_gene915	1.18e-31	128.0	COG0184@1|root,COG0184@2|Bacteria,2NPTZ@2323|unclassified Bacteria	2|Bacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
YHH1_k127_6716774_0	1379698.RBG1_1C00001G1160	1.543e-267	840.0	COG1185@1|root,COG1185@2|Bacteria,2NNX7@2323|unclassified Bacteria	2|Bacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YHH1_k127_6716774_1	1379698.RBG1_1C00001G1161	4.783e-120	400.0	COG0612@1|root,COG0612@2|Bacteria,2NNW3@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_6716774_4	1379698.RBG1_1C00001G1162	2.784e-35	146.0	COG0726@1|root,COG0726@2|Bacteria,2NPY1@2323|unclassified Bacteria	2|Bacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Polysacc_deac_1
YHH1_k127_6716774_2	1379698.RBG1_1C00001G1165	1.958e-82	279.0	COG0495@1|root,COG0495@2|Bacteria,2NNQH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
YHH1_k127_6732334_3	391613.RTM1035_14852	3.583e-92	313.0	COG0732@1|root,COG0732@2|Bacteria,1MXSQ@1224|Proteobacteria,2UB76@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	type I restriction-modification system specificity	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
YHH1_k127_6732334_2	1121447.JONL01000009_gene2529	1.04e-98	334.0	COG1715@1|root,COG1715@2|Bacteria,1RABH@1224|Proteobacteria,42X1S@68525|delta/epsilon subdivisions,2WXD2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6732334_0	1000565.METUNv1_01955	9.203e-144	464.0	28J3D@1|root,2Z8ZM@2|Bacteria,1R4AS@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3644)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3644
YHH1_k127_6732334_1	870187.Thini_3489	3.079e-114	372.0	COG2865@1|root,COG2865@2|Bacteria,1R4MD@1224|Proteobacteria,1RQTX@1236|Gammaproteobacteria,460X9@72273|Thiotrichales	72273|Thiotrichales	K	PFAM ATPase associated with various cellular activities, AAA-4	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_24
YHH1_k127_6740376_0	1121405.dsmv_1237	3.101e-102	342.0	COG1063@1|root,COG1063@2|Bacteria,1MWX0@1224|Proteobacteria,42NCB@68525|delta/epsilon subdivisions,2WJYA@28221|Deltaproteobacteria,2MN4J@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
YHH1_k127_6740376_1	335543.Sfum_1811	3.352e-95	326.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2WJYJ@28221|Deltaproteobacteria,2MQV7@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_6740376_2	335543.Sfum_2848	2.124e-18	85.0	COG0537@1|root,COG0537@2|Bacteria,1PDTP@1224|Proteobacteria,42UAD@68525|delta/epsilon subdivisions,2WQRN@28221|Deltaproteobacteria,2MS5I@213462|Syntrophobacterales	28221|Deltaproteobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
YHH1_k127_6740993_3	864702.OsccyDRAFT_3898	1.141e-07	58.0	COG1216@1|root,COG1216@2|Bacteria,1GBUH@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6740993_1	1259795.ARJK01000002_gene306	9.234e-100	334.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH1_k127_6740993_2	1380356.JNIK01000016_gene3505	3.23e-11	77.0	28MYD@1|root,2ZB59@2|Bacteria,2GMV7@201174|Actinobacteria	201174|Actinobacteria	S	cell wall. Catalyzes the addition of the first key arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-5 of a 6-linked galactofuranosyl (Galf) of the galactan domain, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases	aftA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016757,GO:0016758,GO:0022607,GO:0030312,GO:0034645,GO:0035250,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071766,GO:0071769,GO:0071840,GO:0071944,GO:1901576	2.4.2.46	ko:K13686	-	-	-	-	ko00000,ko01000,ko01003	-	GT85	-	AftA_C,AftA_N
YHH1_k127_6740993_0	247490.KSU1_C0714	5.257e-112	381.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
YHH1_k127_6741734_1	1379698.RBG1_1C00001G0158	1.668e-149	495.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
YHH1_k127_6741734_5	1379698.RBG1_1C00001G0157	6.143e-92	319.0	COG0642@1|root,COG2205@2|Bacteria	1379698.RBG1_1C00001G0157|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6741734_6	857293.CAAU_0463	3.636e-53	201.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,36E3A@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH1_k127_6741734_10	1273103.NM10_10500	7.162e-24	105.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4H2AY@909932|Negativicutes	909932|Negativicutes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH1_k127_6741734_3	1379698.RBG1_1C00001G1549	4.353e-118	385.0	COG0777@1|root,COG0777@2|Bacteria,2NP40@2323|unclassified Bacteria	2|Bacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601	Carboxyl_trans
YHH1_k127_6741734_8	1121335.Clst_2533	2.291e-28	121.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WKHF@541000|Ruminococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
YHH1_k127_6741734_11	1392501.JIAC01000001_gene907	1.149e-20	100.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4H47Z@909932|Negativicutes	909932|Negativicutes	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
YHH1_k127_6741734_7	1291050.JAGE01000001_gene2154	5.803e-30	123.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3WJJ8@541000|Ruminococcaceae	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
YHH1_k127_6741734_0	1379698.RBG1_1C00001G1545	6.084e-178	572.0	COG0745@1|root,COG0745@2|Bacteria,2NNXK@2323|unclassified Bacteria	2|Bacteria	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
YHH1_k127_6741734_4	1379698.RBG1_1C00001G1544	6.689e-111	372.0	COG4191@1|root,COG4191@2|Bacteria,2NPC5@2323|unclassified Bacteria	2|Bacteria	T	Integral membrane sensor signal transduction histidine kinase	vicK	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K07709,ko:K13924	ko02020,ko02030,map02020,map02030	M00499,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
YHH1_k127_6741734_2	224324.aq_298	3.647e-149	484.0	COG0172@1|root,COG0172@2|Bacteria,2G3RF@200783|Aquificae	200783|Aquificae	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YHH1_k127_6741734_9	903818.KI912268_gene3171	1.062e-24	104.0	COG0227@1|root,COG0227@2|Bacteria,3Y5KC@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
YHH1_k127_675035_0	1183438.GKIL_3722	7.83e-204	647.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
YHH1_k127_675035_1	765911.Thivi_0847	6.533e-106	349.0	arCOG09511@1|root,2Z9DH@2|Bacteria,1MXRV@1224|Proteobacteria,1SEJ5@1236|Gammaproteobacteria,1WZGY@135613|Chromatiales	135613|Chromatiales	S	PFAM FRG domain	-	-	-	-	-	-	-	-	-	-	-	-	FRG
YHH1_k127_675035_2	1123073.KB899241_gene2325	3.598e-92	308.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,1S0J9@1236|Gammaproteobacteria,1X3D8@135614|Xanthomonadales	135614|Xanthomonadales	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
YHH1_k127_675035_4	290397.Adeh_2802	6.613e-18	84.0	2EK70@1|root,33DXD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_675035_3	700598.Niako_1367	8.96e-21	94.0	2EJGR@1|root,33D7N@2|Bacteria	2|Bacteria	S	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
YHH1_k127_6752780_1	880073.Calab_0966	2.188e-22	102.0	COG0805@1|root,COG0805@2|Bacteria,2NPGB@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YHH1_k127_6752780_0	1379698.RBG1_1C00001G1448	4.924e-58	205.0	COG1327@1|root,COG1327@2|Bacteria,2NPEU@2323|unclassified Bacteria	2|Bacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
YHH1_k127_6752780_2	211114.JOEF01000008_gene1270	9.277e-06	57.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4E12M@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12
YHH1_k127_679898_1	224325.AF_1054	7.929e-19	92.0	COG1681@1|root,arCOG01829@2157|Archaea,2XXWM@28890|Euryarchaeota	28890|Euryarchaeota	N	Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella	-	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K07325	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
YHH1_k127_679898_0	370438.PTH_2867	4.723e-226	706.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,2607A@186807|Peptococcaceae	186801|Clostridia	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
YHH1_k127_6799458_0	580332.Slit_1802	0.0	1183.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,44VGG@713636|Nitrosomonadales	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH1_k127_6807259_2	1379698.RBG1_1C00001G1252	4.923e-51	186.0	COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria	2|Bacteria	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8,5.4.2.8	ko:K00971,ko:K01840,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01818,R01819	RC00002,RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00940	MannoseP_isomer,NTP_transferase
YHH1_k127_6807259_1	401526.TcarDRAFT_0365	4.498e-59	219.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,4H2DY@909932|Negativicutes	909932|Negativicutes	C	Phosphate acetyl/butaryl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PTA_PTB
YHH1_k127_6807259_0	857293.CAAU_0252	1.774e-65	235.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,36DC6@31979|Clostridiaceae	186801|Clostridia	C	phosphate butyryltransferase	-	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
YHH1_k127_6807259_3	485918.Cpin_2708	2.083e-16	87.0	29WUY@1|root,30IGF@2|Bacteria,4NZFN@976|Bacteroidetes	976|Bacteroidetes	S	NTF2 fold immunity protein	-	-	-	-	-	-	-	-	-	-	-	-	Imm-NTF2-2
YHH1_k127_6811092_7	526222.Desal_2621	3.323e-22	110.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2WKMG@28221|Deltaproteobacteria,2M7UB@213115|Desulfovibrionales	28221|Deltaproteobacteria	MU	outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
YHH1_k127_6811092_9	1382356.JQMP01000001_gene894	5.467e-10	68.0	COG1309@1|root,COG1309@2|Bacteria,2G7DR@200795|Chloroflexi,27Y8Z@189775|Thermomicrobia	189775|Thermomicrobia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
YHH1_k127_6811092_3	2325.TKV_c18590	4.489e-61	223.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,42F3P@68295|Thermoanaerobacterales	186801|Clostridia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YHH1_k127_6811092_4	1379698.RBG1_1C00001G1771	7.59e-51	194.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YHH1_k127_6811092_6	1379698.RBG1_1C00001G1772	1.862e-25	116.0	COG0457@1|root,COG0457@2|Bacteria,2NQ3H@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
YHH1_k127_6811092_1	1379698.RBG1_1C00001G1773	5.26e-108	373.0	COG0457@1|root,COG0457@2|Bacteria,2NP5J@2323|unclassified Bacteria	2|Bacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
YHH1_k127_6811092_8	316274.Haur_4899	9.155e-17	89.0	COG0457@1|root,COG0457@2|Bacteria	316274.Haur_4899|-	S	peptidyl-tyrosine sulfation	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	-
YHH1_k127_6811092_2	880073.Calab_2475	3.09e-97	329.0	COG2304@1|root,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
YHH1_k127_6811092_0	1379698.RBG1_1C00001G1775	1.277e-108	362.0	COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria	2|Bacteria	NU	von Willebrand factor (vWF) type A domain	batA	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
YHH1_k127_6811092_5	1379698.RBG1_1C00001G1776	3e-44	174.0	COG3088@1|root,COG3088@2|Bacteria,2NS4V@2323|unclassified Bacteria	2|Bacteria	O	subunit of a heme lyase	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564	-	ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmH
YHH1_k127_6850593_0	1282361.ABAC402_17860	2.744e-88	299.0	COG3741@1|root,COG3741@2|Bacteria,1N949@1224|Proteobacteria,2US2U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
YHH1_k127_6850593_1	237368.SCABRO_00472	0.0001465	48.0	2CK24@1|root,33099@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6882745_1	1499967.BAYZ01000036_gene2419	5.535e-170	544.0	COG2152@1|root,COG2152@2|Bacteria,2NPB8@2323|unclassified Bacteria	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
YHH1_k127_6882745_0	1499967.BAYZ01000036_gene2418	0.0	1191.0	COG0438@1|root,COG0438@2|Bacteria,2NNZH@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_6882745_15	1033802.SSPSH_000617	1.549e-10	65.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_6882745_16	111780.Sta7437_4145	2.41e-08	61.0	COG1359@1|root,COG1359@2|Bacteria,1GB91@1117|Cyanobacteria,3VKT8@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
YHH1_k127_6882745_10	765913.ThidrDRAFT_1659	2.164e-20	95.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,1WZ7R@135613|Chromatiales	135613|Chromatiales	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_6882745_5	1379270.AUXF01000001_gene2611	1.814e-53	196.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,GerE,PocR,Response_reg
YHH1_k127_6882745_3	521674.Plim_3136	4.782e-57	211.0	COG2148@1|root,COG2148@2|Bacteria,2IX7E@203682|Planctomycetes	203682|Planctomycetes	M	involved in lipopolysaccharide	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
YHH1_k127_6882745_8	1121104.AQXH01000001_gene858	8.083e-31	130.0	COG1595@1|root,COG1595@2|Bacteria,4NT79@976|Bacteroidetes,1IZNZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_6882745_4	1120999.JONM01000023_gene3200	3.104e-56	203.0	COG2095@1|root,COG2095@2|Bacteria,1MV1C@1224|Proteobacteria,2VKRW@28216|Betaproteobacteria,2KR9I@206351|Neisseriales	206351|Neisseriales	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
YHH1_k127_6882745_6	1379270.AUXF01000001_gene2611	1.206e-37	149.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,GerE,PocR,Response_reg
YHH1_k127_6882745_12	1298864.AUEQ01000001_gene4257	2.062e-13	78.0	COG1595@1|root,COG1595@2|Bacteria,2I8V8@201174|Actinobacteria,238G2@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_6882745_9	1379698.RBG1_1C00001G0639	2.914e-27	115.0	COG2088@1|root,COG2088@2|Bacteria,2NQ05@2323|unclassified Bacteria	2|Bacteria	D	SpoVG	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
YHH1_k127_6882745_11	204669.Acid345_4293	2.114e-15	85.0	COG2823@1|root,COG2823@2|Bacteria,3Y99E@57723|Acidobacteria,2JP08@204432|Acidobacteriia	204432|Acidobacteriia	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6882745_2	525897.Dbac_2185	5.609e-68	239.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,42RMP@68525|delta/epsilon subdivisions,2X5PZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
YHH1_k127_6882745_13	521719.ATXQ01000004_gene1914	9.018e-13	70.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,1SHEH@1236|Gammaproteobacteria,1YKBP@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6882745_14	118005.AWNK01000007_gene734	2.22e-12	70.0	2DRFV@1|root,33BJD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
YHH1_k127_6912224_4	1379698.RBG1_1C00001G0668	1.115e-14	88.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	DUF1566,Phenol_MetA_deg
YHH1_k127_6912224_3	1457250.BBMO01000002_gene2310	9.705e-21	108.0	COG0419@1|root,arCOG00368@2157|Archaea	2157|Archaea	L	Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex	-	-	-	-	-	-	-	-	-	-	-	-	MMPL,PQQ_2,Peptidase_S74,Pkinase
YHH1_k127_6912224_1	1379698.RBG1_1C00001G0608	2.721e-108	385.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
YHH1_k127_6912224_0	1379698.RBG1_1C00001G0608	1.048e-139	472.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
YHH1_k127_6912224_2	1396141.BATP01000042_gene1909	3.372e-106	356.0	COG3829@1|root,COG3829@2|Bacteria,46UZT@74201|Verrucomicrobia,2IVHE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
YHH1_k127_6973175_5	215803.DB30_0018	5.687e-73	259.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,2YZTX@29|Myxococcales	28221|Deltaproteobacteria	M	Lipid-A-disaccharide synthetase	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
YHH1_k127_6973175_4	945713.IALB_1051	1.81e-78	273.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA
YHH1_k127_6973175_9	880073.Calab_2217	8.069e-12	77.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
YHH1_k127_6973175_1	1379698.RBG1_1C00001G1648	5.216e-96	320.0	COG1043@1|root,COG1043@2|Bacteria,2NP5V@2323|unclassified Bacteria	2|Bacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
YHH1_k127_6973175_0	1379698.RBG1_1C00001G1649	1.31e-202	639.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2NNYX@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022	-	-	-	FabA,LpxC
YHH1_k127_6973175_2	1382358.JHVN01000001_gene959	4.42e-88	310.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,21V7N@150247|Anoxybacillus	91061|Bacilli	J	Uncharacterized protein family UPF0004	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YHH1_k127_6973175_6	700598.Niako_4283	5.02e-27	128.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1IVP5@117747|Sphingobacteriia	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
YHH1_k127_6973175_7	1379698.RBG1_1C00001G0282	4.001e-23	115.0	COG5276@1|root,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,LVIVD
YHH1_k127_6973175_3	314285.KT71_11209	9.122e-86	295.0	2DCFR@1|root,2ZDYQ@2|Bacteria,1RB5X@1224|Proteobacteria,1RN4F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6973175_8	96561.Dole_1704	1.691e-19	102.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6977139_0	398767.Glov_0712	6.85e-157	499.0	COG0371@1|root,COG0371@2|Bacteria,1MWAE@1224|Proteobacteria,42PJS@68525|delta/epsilon subdivisions,2WJ69@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Iron-containing alcohol dehydrogenase	-	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
YHH1_k127_6977139_1	502025.Hoch_0991	2.423e-61	217.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH1_k127_7022773_0	717231.Flexsi_2005	5.636e-43	168.0	COG3005@1|root,COG3005@2|Bacteria,2GF5I@200930|Deferribacteres	200930|Deferribacteres	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YHH1_k127_7022773_3	121225.PHUM345830-PA	6.415e-05	55.0	COG0457@1|root,KOG0548@2759|Eukaryota,38GCK@33154|Opisthokonta,3BECN@33208|Metazoa,3CUW9@33213|Bilateria,41W4B@6656|Arthropoda,3SK6G@50557|Insecta,3EA5V@33342|Paraneoptera	33208|Metazoa	O	Tetratricopeptide repeat	STIP1	GO:0000003,GO:0003674,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005829,GO:0006950,GO:0007275,GO:0007568,GO:0008022,GO:0008150,GO:0008340,GO:0009266,GO:0009408,GO:0009628,GO:0010259,GO:0012505,GO:0030234,GO:0030544,GO:0031072,GO:0032501,GO:0032502,GO:0032780,GO:0032991,GO:0042030,GO:0043086,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043462,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0048856,GO:0050790,GO:0050896,GO:0051087,GO:0051336,GO:0051346,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0098772,GO:0101031	-	ko:K04734,ko:K09553,ko:K16362	ko04024,ko04062,ko04064,ko04210,ko04380,ko04620,ko04621,ko04622,ko04623,ko04624,ko04657,ko04658,ko04659,ko04660,ko04662,ko04668,ko04722,ko04920,ko04926,ko04931,ko05020,ko05120,ko05131,ko05134,ko05140,ko05142,ko05145,ko05160,ko05161,ko05162,ko05164,ko05166,ko05167,ko05168,ko05169,ko05200,ko05203,ko05215,ko05220,ko05222,map04024,map04062,map04064,map04210,map04380,map04620,map04621,map04622,map04623,map04624,map04657,map04658,map04659,map04660,map04662,map04668,map04722,map04920,map04926,map04931,map05020,map05120,map05131,map05134,map05140,map05142,map05145,map05160,map05161,map05162,map05164,map05166,map05167,map05168,map05169,map05200,map05203,map05215,map05220,map05222	M00686	-	-	ko00000,ko00001,ko00002,ko03000,ko03110,ko04131,ko04516	-	-	-	TPR_1,TPR_11,TPR_12,TPR_16,TPR_2,TPR_8
YHH1_k127_7022773_1	1461580.CCAS010000009_gene1274	1.179e-31	133.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,4H9MD@91061|Bacilli,1ZQQB@1386|Bacillus	91061|Bacilli	N	Flagellar motor protein	ytxE	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
YHH1_k127_7022773_2	644966.Tmar_0692	2.265e-11	64.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,3WDNX@538999|Clostridiales incertae sedis	186801|Clostridia	N	OmpA family	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
YHH1_k127_7053926_0	1123508.JH636450_gene7172	2.293e-11	71.0	2FCU9@1|root,344X8@2|Bacteria,2J408@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7085562_2	1232410.KI421426_gene1498	9.153e-28	118.0	COG3713@1|root,COG3713@2|Bacteria,1N0BC@1224|Proteobacteria,437BN@68525|delta/epsilon subdivisions,2X2GT@28221|Deltaproteobacteria,43VCY@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	MltA-interacting protein MipA	-	-	-	-	-	-	-	-	-	-	-	-	MipA
YHH1_k127_7085562_0	96561.Dole_3014	6.118e-82	276.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,42QRV@68525|delta/epsilon subdivisions,2WMUE@28221|Deltaproteobacteria,2MJY2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YHH1_k127_7085562_4	690850.Desaf_2484	2.573e-12	66.0	COG2391@1|root,COG2391@2|Bacteria,1RDQK@1224|Proteobacteria,42RU6@68525|delta/epsilon subdivisions,2WNJT@28221|Deltaproteobacteria,2MBSU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YHH1_k127_7085562_1	338966.Ppro_1978	1.148e-54	195.0	COG2391@1|root,COG2391@2|Bacteria,1RDQK@1224|Proteobacteria,42RU6@68525|delta/epsilon subdivisions,2WNJT@28221|Deltaproteobacteria,43UP0@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YHH1_k127_7085562_3	243231.GSU0729	2.673e-17	85.0	COG0348@1|root,COG0348@2|Bacteria,1Q1GZ@1224|Proteobacteria,42TN5@68525|delta/epsilon subdivisions,2WQIA@28221|Deltaproteobacteria,43V5F@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
YHH1_k127_7089663_1	573413.Spirs_2400	3.029e-40	154.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15,2.7.13.3	ko:K03564,ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AhpC-TSA
YHH1_k127_7089663_2	1504319.GM45_4250	8.919e-10	62.0	COG3369@1|root,COG3369@2|Bacteria	2|Bacteria	I	Iron-binding zinc finger CDGSH type	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	zf-CDGSH
YHH1_k127_7089663_0	1173028.ANKO01000057_gene6232	6.592e-53	194.0	COG0664@1|root,COG0664@2|Bacteria,1G3SU@1117|Cyanobacteria,1H8VY@1150|Oscillatoriales	1117|Cyanobacteria	K	Cyclic nucleotide-binding domain	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YHH1_k127_7112110_0	909663.KI867150_gene1668	3.947e-61	225.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42M62@68525|delta/epsilon subdivisions,2WJ83@28221|Deltaproteobacteria,2MQAJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
YHH1_k127_7112110_2	1121406.JAEX01000003_gene1510	9.053e-12	78.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2WK7H@28221|Deltaproteobacteria,2M7UE@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
YHH1_k127_7112110_3	1415774.U728_884	0.0009779	51.0	COG0627@1|root,COG0627@2|Bacteria,1UJH7@1239|Firmicutes,25F2Y@186801|Clostridia,36FIM@31979|Clostridiaceae	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YHH1_k127_7112110_1	1121285.AUFK01000017_gene3022	1.11e-40	159.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1HWWB@117743|Flavobacteriia,3ZQPQ@59732|Chryseobacterium	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
YHH1_k127_713754_1	1343739.PAP_00945	2.833e-53	204.0	COG1906@1|root,arCOG04354@2157|Archaea,2XX2X@28890|Euryarchaeota,243P4@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
YHH1_k127_713754_0	293826.Amet_2158	3.161e-74	266.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,36DMY@31979|Clostridiaceae	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
YHH1_k127_713754_2	986075.CathTA2_0205	8.687e-11	68.0	COG0115@1|root,COG0115@2|Bacteria,1TSIP@1239|Firmicutes,4HC7K@91061|Bacilli	91061|Bacilli	EH	4-amino-4-deoxychorismate lyase	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
YHH1_k127_7138672_4	1047013.AQSP01000053_gene289	1.089e-39	161.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH1_k127_7138672_0	635013.TherJR_0008	8.071e-271	847.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,260WQ@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH1_k127_7138672_7	1287475.HMPREF1650_05150	6.468e-05	51.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,22N7D@1653|Corynebacteriaceae	201174|Actinobacteria	S	Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
YHH1_k127_7138672_5	1237149.C900_05496	4.689e-25	114.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47RTK@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
YHH1_k127_7138672_3	1379698.RBG1_1C00001G0295	4.113e-61	219.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	ko:K04013,ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C552,Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1
YHH1_k127_7138672_2	1379698.RBG1_1C00001G0296	3.246e-89	302.0	COG0437@1|root,COG0437@2|Bacteria,2NR78@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S binding domain	ttrB	-	-	ko:K08358	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Fer4_11,Fer4_3,Fer4_7
YHH1_k127_7138672_1	1379698.RBG1_1C00001G0297	1.008e-158	511.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
YHH1_k127_713874_4	1340493.JNIF01000003_gene4252	3.499e-47	177.0	COG0122@1|root,COG0122@2|Bacteria,3Y582@57723|Acidobacteria	57723|Acidobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YHH1_k127_713874_0	1379698.RBG1_1C00001G0471	1.89e-222	698.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH1_k127_713874_1	880073.Calab_0633	4.076e-200	632.0	COG2403@1|root,COG2403@2|Bacteria,2NNTB@2323|unclassified Bacteria	2|Bacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	cpgS	-	-	ko:K05716	-	-	R03298	RC00900	ko00000,ko01000	-	-	-	cobW
YHH1_k127_713874_3	1379698.RBG1_1C00001G0473	2.241e-118	389.0	COG0549@1|root,COG0549@2|Bacteria,2NNKM@2323|unclassified Bacteria	2|Bacteria	E	Amino acid kinase family	arcC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3652,iE2348C_1286.E2348C_0454,iECABU_c1320.ECABU_c31550,iECED1_1282.ECED1_0540,iECED1_1282.ECED1_3334,iECIAI39_1322.ECIAI39_3289,iECNA114_1301.ECNA114_2915,iECOK1_1307.ECOK1_3260,iECS88_1305.ECS88_3153,iECSF_1327.ECSF_2670,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iHN637.CLJU_RS13830,iJN746.PP_0999,iUMN146_1321.UM146_02150,iUTI89_1310.UTI89_C3259,ic_1306.c3452	AA_kinase
YHH1_k127_713874_2	1379698.RBG1_1C00001G0474	9.235e-146	476.0	COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria	2|Bacteria	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
YHH1_k127_713874_5	1379698.RBG1_1C00001G0475	2.36e-28	115.0	COG0045@1|root,COG0045@2|Bacteria,2NNQA@2323|unclassified Bacteria	2|Bacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009361,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0042709,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494	6.2.1.5,6.2.1.9	ko:K01903,ko:K14067	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261,iPC815.YPO1115,iUMNK88_1353.UMNK88_764,iYO844.BSU16090	ATP-grasp_2,Ligase_CoA
YHH1_k127_7140235_0	340099.Teth39_1216	1.884e-128	420.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,42FDK@68295|Thermoanaerobacterales	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
YHH1_k127_7140235_1	1211817.CCAT010000043_gene3472	1.114e-49	183.0	COG0655@1|root,COG0655@2|Bacteria,1UHW0@1239|Firmicutes,24N5N@186801|Clostridia,36VWG@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
YHH1_k127_7140235_3	323259.Mhun_1807	7.821e-05	51.0	COG1633@1|root,arCOG01102@2157|Archaea	2157|Archaea	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YHH1_k127_71497_4	498761.HM1_2200	0.0007745	42.0	COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,25E6Z@186801|Clostridia	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH1_k127_71497_2	671143.DAMO_2709	5.288e-56	201.0	COG1005@1|root,COG1005@2|Bacteria,2NQIK@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00337,ko:K05572	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH1_k127_71497_0	1123511.KB905842_gene1665	1.011e-126	415.0	COG0649@1|root,COG0649@2|Bacteria,1TQAR@1239|Firmicutes,4H2Z2@909932|Negativicutes	909932|Negativicutes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
YHH1_k127_71497_3	1121121.KB894284_gene535	8.606e-27	115.0	COG0852@1|root,COG0852@2|Bacteria,1UFNI@1239|Firmicutes,4HDV1@91061|Bacilli,26RPJ@186822|Paenibacillaceae	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
YHH1_k127_71497_1	1279009.ADICEAN_01551	1.525e-60	214.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,47JYD@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YHH1_k127_7159010_0	1121930.AQXG01000011_gene1763	1.259e-128	432.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.50	ko:K01337,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4397,Peptidase_S8,Trypsin_2
YHH1_k127_7159010_1	713586.KB900536_gene328	9.292e-31	126.0	COG2133@1|root,COG2133@2|Bacteria,1QWB2@1224|Proteobacteria	1224|Proteobacteria	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
YHH1_k127_716690_0	1287116.X734_00245	0.0	1153.0	COG0293@1|root,COG0438@1|root,COG1216@1|root,COG0293@2|Bacteria,COG0438@2|Bacteria,COG1216@2|Bacteria,1MU9C@1224|Proteobacteria,2TQJM@28211|Alphaproteobacteria,43HA8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	lpcC	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glycos_transf_1
YHH1_k127_7178553_3	1379698.RBG1_1C00001G1136	5.405e-11	67.0	COG2956@1|root,COG2956@2|Bacteria	2|Bacteria	G	lipopolysaccharide metabolic process	ciaB	-	-	ko:K07502,ko:K08309,ko:K19804,ko:K21572	-	-	-	-	ko00000,ko01000,ko01011,ko02000	8.A.46.1,8.A.46.3	GH23	-	SusD-like_3,SusD_RagB,TPR_16,TPR_6,TPR_8
YHH1_k127_7178553_0	518766.Rmar_1542	1.082e-234	754.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1FJ5H@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
YHH1_k127_7178553_1	314230.DSM3645_19987	2.046e-121	412.0	COG0323@1|root,COG0323@2|Bacteria,2IXI2@203682|Planctomycetes	203682|Planctomycetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
YHH1_k127_7178553_2	1232410.KI421414_gene2902	3.449e-69	247.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,43U4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YHH1_k127_7192738_5	690850.Desaf_1348	5.177e-79	271.0	2DM0H@1|root,316A1@2|Bacteria,1N0X9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7192738_17	661367.LLO_0769	1.537e-09	63.0	2ECSH@1|root,336Q2@2|Bacteria,1QBQ8@1224|Proteobacteria,1T7A9@1236|Gammaproteobacteria,1JF4B@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7192738_11	272630.MexAM1_META1p1854	1.146e-30	129.0	COG4828@1|root,COG4828@2|Bacteria,1N984@1224|Proteobacteria,2UBT7@28211|Alphaproteobacteria,1JY2F@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
YHH1_k127_7192738_14	1136417.AZWE01000033_gene487	4.248e-18	88.0	COG1225@1|root,COG1225@2|Bacteria,2HUEK@201174|Actinobacteria,4DENW@85008|Micromonosporales	201174|Actinobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH1_k127_7192738_18	1121381.JNIV01000031_gene2418	1.652e-08	56.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH1_k127_7192738_9	518766.Rmar_1610	4.4e-53	194.0	COG2032@1|root,COG2032@2|Bacteria,4NM88@976|Bacteroidetes	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
YHH1_k127_7192738_10	290397.Adeh_0959	5.208e-33	128.0	2DJKR@1|root,32YT5@2|Bacteria,1NACC@1224|Proteobacteria,433SU@68525|delta/epsilon subdivisions,2WY45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7192738_15	335543.Sfum_1432	8.984e-17	88.0	COG3350@1|root,COG3350@2|Bacteria,1NE2T@1224|Proteobacteria,42VZQ@68525|delta/epsilon subdivisions,2WSDU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
YHH1_k127_7192738_8	1232410.KI421424_gene1590	9.859e-55	205.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43C4K@68525|delta/epsilon subdivisions,2X7F1@28221|Deltaproteobacteria,43TX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains HisKA, HATPase_c	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YHH1_k127_7192738_2	269799.Gmet_2453	7.305e-141	461.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43TS4@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02481,ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_7192738_12	261292.Nit79A3_2691	2.424e-25	120.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria,372KF@32003|Nitrosomonadales	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH1_k127_7192738_4	290397.Adeh_4105	1.075e-99	346.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2YZUC@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
YHH1_k127_7192738_0	1192034.CAP_8124	0.0	1296.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
YHH1_k127_7192738_3	314230.DSM3645_05435	1.704e-132	436.0	COG1236@1|root,COG1236@2|Bacteria,2IXNS@203682|Planctomycetes	203682|Planctomycetes	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
YHH1_k127_7192738_7	945713.IALB_0032	3.132e-57	203.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
YHH1_k127_7192738_1	525897.Dbac_2058	4.509e-146	481.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2WJ5J@28221|Deltaproteobacteria,2M7RB@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
YHH1_k127_7192738_16	1242864.D187_007276	1.026e-13	79.0	COG0468@1|root,COG0468@2|Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553,ko:K14160	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
YHH1_k127_7192738_13	240015.ACP_3198	3.516e-23	115.0	COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria,2JIUC@204432|Acidobacteriia	204432|Acidobacteriia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
YHH1_k127_7192738_6	635013.TherJR_1036	9.686e-65	230.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YHH1_k127_7249606_1	1123057.P872_07600	9.253e-11	65.0	COG1835@1|root,COG1835@2|Bacteria,4P9PE@976|Bacteroidetes,47RSK@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
YHH1_k127_7249606_0	1089550.ATTH01000001_gene883	2.407e-118	398.0	COG0318@1|root,COG0318@2|Bacteria,4NDYR@976|Bacteroidetes,1FIJ3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
YHH1_k127_725157_1	794903.OPIT5_29980	7.546e-27	128.0	2EX0Y@1|root,33QC4@2|Bacteria,46UUA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_725157_0	382464.ABSI01000016_gene633	3.99e-115	392.0	COG0749@1|root,COG0749@2|Bacteria	2|Bacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA_2	-	2.7.7.7	ko:K02334,ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A
YHH1_k127_7254429_9	768710.DesyoDRAFT_0694	1.532e-29	119.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25ZZ5@186807|Peptococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH1_k127_7254429_10	797209.ZOD2009_03160	1.72e-26	119.0	COG0791@1|root,2N59G@2157|Archaea,2XWZY@28890|Euryarchaeota,23VA0@183963|Halobacteria	183963|Halobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
YHH1_k127_7254429_5	1382306.JNIM01000001_gene2893	2.124e-42	169.0	COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing protein	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YHH1_k127_7254429_1	1379698.RBG1_1C00001G0881	3.743e-111	383.0	COG0860@1|root,COG0860@2|Bacteria,2NQ79@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,GHL10,SpoIID
YHH1_k127_7254429_3	1379698.RBG1_1C00001G0669	2.617e-59	217.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	Peptidase_M56
YHH1_k127_7254429_8	404589.Anae109_0401	4.403e-32	132.0	COG2154@1|root,COG2154@2|Bacteria,1RIEN@1224|Proteobacteria,43765@68525|delta/epsilon subdivisions,2X24N@28221|Deltaproteobacteria,2YW4N@29|Myxococcales	28221|Deltaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YHH1_k127_7254429_2	1317122.ATO12_25110	8.843e-78	272.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1HY38@117743|Flavobacteriia,2YJ4Z@290174|Aquimarina	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
YHH1_k127_7254429_6	192952.MM_1928	7.167e-40	153.0	COG1247@1|root,arCOG00830@2157|Archaea,2Y6Y1@28890|Euryarchaeota,2NAZ6@224756|Methanomicrobia	224756|Methanomicrobia	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
YHH1_k127_7254429_7	335543.Sfum_2004	9.421e-36	141.0	COG1247@1|root,COG1247@2|Bacteria,1RDNE@1224|Proteobacteria,42TWQ@68525|delta/epsilon subdivisions,2WR2E@28221|Deltaproteobacteria,2MS2P@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
YHH1_k127_7254429_11	935948.KE386495_gene2082	9.163e-19	93.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24P0N@186801|Clostridia,42GJC@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
YHH1_k127_7254429_4	1121920.AUAU01000006_gene301	7.511e-49	181.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7254429_0	1379698.RBG1_1C00001G1150	3.871e-205	654.0	COG0442@1|root,COG0442@2|Bacteria,2NNNH@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iJN678.proS,iUTI89_1310.UTI89_C0210	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
YHH1_k127_7258677_5	1396141.BATP01000057_gene3074	0.0005807	50.0	COG0265@1|root,COG0265@2|Bacteria,46XAI@74201|Verrucomicrobia,2IUH0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YHH1_k127_7258677_1	391615.ABSJ01000005_gene583	4.342e-58	212.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1J4DJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YHH1_k127_7258677_4	945713.IALB_0757	2.641e-08	68.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_7258677_0	316274.Haur_1687	6.012e-137	442.0	COG0667@1|root,COG0667@2|Bacteria,2G5YU@200795|Chloroflexi,376EH@32061|Chloroflexia	32061|Chloroflexia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH1_k127_7258677_2	913865.DOT_2964	3.78e-48	178.0	COG2318@1|root,COG2318@2|Bacteria,1V8MI@1239|Firmicutes	1239|Firmicutes	S	PFAM DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YHH1_k127_7258677_3	649747.HMPREF0083_02105	1.006e-26	112.0	COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,26VEY@186822|Paenibacillaceae	91061|Bacilli	Q	synthase	bcsA	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
YHH1_k127_7273847_0	861299.J421_3613	4.294e-272	857.0	COG3808@1|root,COG3808@2|Bacteria,1ZT09@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
YHH1_k127_7273847_1	314292.VAS14_15724	1.513e-10	63.0	2DPZZ@1|root,3345G@2|Bacteria,1N8ZZ@1224|Proteobacteria,1T6AC@1236|Gammaproteobacteria,1XZA4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7273847_2	1198114.AciX9_0586	9.385e-08	57.0	COG3206@1|root,COG3206@2|Bacteria,3Y2PJ@57723|Acidobacteria,2JHP9@204432|Acidobacteriia	204432|Acidobacteriia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
YHH1_k127_7276140_6	194439.CT0299	3.584e-22	100.0	COG0008@1|root,COG0008@2|Bacteria,1FDMJ@1090|Chlorobi	1090|Chlorobi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH1_k127_7276140_9	880073.Calab_1548	4.906e-09	64.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YHH1_k127_7276140_8	760568.Desku_0069	1.19e-10	63.0	COG1592@1|root,COG1592@2|Bacteria,1VB12@1239|Firmicutes,24JQ6@186801|Clostridia,262FT@186807|Peptococcaceae	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7276140_5	926569.ANT_29600	2.534e-48	178.0	COG0695@1|root,COG1225@1|root,COG0695@2|Bacteria,COG1225@2|Bacteria,2G6XD@200795|Chloroflexi	200795|Chloroflexi	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH1_k127_7276140_1	235909.GK2954	1.4e-108	363.0	COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,1WEJX@129337|Geobacillus	91061|Bacilli	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	yumC	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	iYO844.BSU32110	Pyr_redox_2
YHH1_k127_7276140_0	1379698.RBG1_1C00001G1873	1.201e-130	426.0	COG0379@1|root,COG0379@2|Bacteria,2NP47@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
YHH1_k127_7276140_2	1379698.RBG1_1C00001G0523	5.287e-99	340.0	COG0508@1|root,COG0508@2|Bacteria,2NNZ8@2323|unclassified Bacteria	2|Bacteria	C	e3 binding domain	sucB	GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	2.3.1.168,2.3.1.61	ko:K00658,ko:K09699	ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036	R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02833,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH1_k127_7276140_4	555079.Toce_0610	2.167e-48	183.0	COG0321@1|root,COG0321@2|Bacteria,1V44P@1239|Firmicutes,24GE9@186801|Clostridia,42FUN@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YHH1_k127_7276140_3	1379698.RBG1_1C00001G1834	1.387e-69	244.0	COG1028@1|root,COG1028@2|Bacteria,2NQVI@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH1_k127_7304578_1	1122603.ATVI01000005_gene3276	1.236e-29	119.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,1X4PX@135614|Xanthomonadales	135614|Xanthomonadales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YHH1_k127_7304578_0	1163617.SCD_n01952	1.417e-75	262.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria	1224|Proteobacteria	P	part of a sulfur-relay system	tusE	GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
YHH1_k127_7314167_0	1125863.JAFN01000001_gene1255	4.137e-61	215.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH1_k127_7314167_1	572477.Alvin_2949	1.716e-53	192.0	COG0346@1|root,COG0346@2|Bacteria,1QK95@1224|Proteobacteria,1SD7T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YHH1_k127_7314167_2	340177.Cag_1103	3.83e-37	142.0	COG2929@1|root,COG2929@2|Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH1_k127_7327320_0	315749.Bcer98_2220	3.837e-39	167.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,1ZAZE@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	PPC,Peptidase_S8
YHH1_k127_7327320_1	234267.Acid_3133	3.154e-21	107.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y7SH@57723|Acidobacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,PD40,TPR_10,TPR_12,TPR_8
YHH1_k127_7329800_2	1379698.RBG1_1C00001G1879	8.203e-81	274.0	COG1154@1|root,COG1154@2|Bacteria,2NNNA@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527	DXP_synthase_N,Transket_pyr,Transketolase_C
YHH1_k127_7329800_3	926692.AZYG01000061_gene1383	5.289e-80	276.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3WAJ4@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH1_k127_7329800_5	1123252.ATZF01000001_gene1345	4.861e-12	68.0	COG1722@1|root,COG1722@2|Bacteria,1TU8J@1239|Firmicutes,4I3UW@91061|Bacilli,27CBG@186824|Thermoactinomycetaceae	91061|Bacilli	L	Exonuclease VII small subunit	-	-	-	-	-	-	-	-	-	-	-	-	Exonuc_VII_S
YHH1_k127_7329800_1	1379698.RBG1_1C00001G1127	1.042e-103	350.0	COG1570@1|root,COG1570@2|Bacteria,2NNQT@2323|unclassified Bacteria	2|Bacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6,3.4.21.102	ko:K03601,ko:K03797	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
YHH1_k127_7329800_0	1379698.RBG1_1C00001G1025	5.979e-199	638.0	COG0322@1|root,COG0322@2|Bacteria,2NNQ4@2323|unclassified Bacteria	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
YHH1_k127_7329800_4	1382358.JHVN01000009_gene3326	4.444e-29	122.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HH84@91061|Bacilli,21WTM@150247|Anoxybacillus	91061|Bacilli	M	NlpC/P60 family	lytE	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3,SLH
YHH1_k127_7341607_0	1463861.JNXE01000019_gene6080	3.892e-230	733.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,2GTBI@201174|Actinobacteria	201174|Actinobacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA
YHH1_k127_7341607_1	1323361.JPOC01000014_gene3712	5.619e-23	108.0	COG0438@1|root,COG0438@2|Bacteria,2HQQW@201174|Actinobacteria,4G6SU@85025|Nocardiaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
YHH1_k127_7344672_4	1379698.RBG1_1C00001G0278	1.794e-138	447.0	COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH1_k127_7344672_14	443143.GM18_3158	1.206e-41	160.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,437IE@68525|delta/epsilon subdivisions,2WVS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
YHH1_k127_7344672_11	864702.OsccyDRAFT_2250	5.437e-54	196.0	COG1670@1|root,COG1670@2|Bacteria,1G5HU@1117|Cyanobacteria,1HB9F@1150|Oscillatoriales	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
YHH1_k127_7344672_3	429009.Adeg_1891	1.203e-151	497.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42FXP@68295|Thermoanaerobacterales	186801|Clostridia	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YHH1_k127_7344672_15	360104.CCC13826_0482	2.114e-24	106.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2YQAF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RNA-binding protein	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_7344672_6	868595.Desca_1885	8.786e-78	273.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,260TE@186807|Peptococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
YHH1_k127_7344672_9	1379698.RBG1_1C00001G0429	1.579e-61	220.0	COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria	2|Bacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YHH1_k127_7344672_12	1192034.CAP_4484	3.766e-51	202.0	COG1621@1|root,COG1807@1|root,COG1621@2|Bacteria,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7344672_2	945713.IALB_2371	4.028e-259	810.0	COG0481@1|root,COG0481@2|Bacteria	2|Bacteria	M	GTPase activity	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YHH1_k127_7344672_10	411465.PEPMIC_01312	6.741e-55	205.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,22GKV@1570339|Peptoniphilaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
YHH1_k127_7344672_5	1379698.RBG1_1C00001G1625	1.053e-87	298.0	COG0294@1|root,COG0294@2|Bacteria,2NNN7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
YHH1_k127_7344672_8	648996.Theam_1364	7.374e-62	218.0	COG0302@1|root,COG0302@2|Bacteria,2G40B@200783|Aquificae	200783|Aquificae	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
YHH1_k127_7344672_1	1379698.RBG1_1C00001G1627	3.187e-262	822.0	COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YHH1_k127_7344672_13	1118054.CAGW01000082_gene2989	1.007e-41	159.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,26SCN@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,6.3.4.19	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000,ko03016	-	-	-	Pribosyltran
YHH1_k127_7344672_7	1304880.JAGB01000002_gene2320	7.445e-70	254.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
YHH1_k127_7344672_0	1379698.RBG1_1C00001G0338	1.311e-311	974.0	COG0046@1|root,COG0046@2|Bacteria,2NNPS@2323|unclassified Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH1_k127_7344672_16	1379698.RBG1_1C00001G0582	1.187e-05	54.0	COG2911@1|root,COG2911@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cohesin,FlgD_ig,Peptidase_S74
YHH1_k127_7357188_1	1237149.C900_05913	6.914e-69	245.0	COG4677@1|root,COG4704@1|root,COG5184@1|root,COG5492@1|root,COG4677@2|Bacteria,COG4704@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4PN9Q@976|Bacteroidetes,47Y9H@768503|Cytophagia	976|Bacteroidetes	DZ	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
YHH1_k127_7357188_2	756272.Plabr_0919	1.018e-41	173.0	COG1409@1|root,COG1409@2|Bacteria,2J2TN@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH1_k127_7357188_0	118173.KB235914_gene858	0.0	1163.0	COG0376@1|root,COG0376@2|Bacteria,1G1NM@1117|Cyanobacteria,1H83F@1150|Oscillatoriales	1117|Cyanobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
YHH1_k127_7357188_3	903818.KI912268_gene3050	5.287e-36	140.0	COG0735@1|root,COG0735@2|Bacteria,3Y7UH@57723|Acidobacteria	57723|Acidobacteria	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH1_k127_7371302_0	717231.Flexsi_1411	3.757e-98	343.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
YHH1_k127_7371302_1	1122222.AXWR01000037_gene279	2.221e-10	66.0	COG2372@1|root,COG4733@1|root,COG2372@2|Bacteria,COG4733@2|Bacteria,1WN17@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
YHH1_k127_7371557_1	1379698.RBG1_1C00001G0120	9.53e-24	101.0	28II6@1|root,2Z8JB@2|Bacteria,2NNT1@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7371557_0	1379698.RBG1_1C00001G0122	3.428e-293	910.0	COG1070@1|root,COG1070@2|Bacteria,2NP2A@2323|unclassified Bacteria	2|Bacteria	G	MutL protein	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N,MutL
YHH1_k127_7397778_2	795359.TOPB45_0365	7.864e-46	181.0	COG1596@1|root,COG1596@2|Bacteria,2GI4R@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YHH1_k127_7397778_4	1408164.MOLA814_02372	1.543e-11	76.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHX2@28216|Betaproteobacteria,1KQHB@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_7397778_1	1047013.AQSP01000112_gene393	1.58e-82	293.0	COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	cpsE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3,STAS
YHH1_k127_7397778_3	1379698.RBG1_1C00001G1726	1.246e-37	160.0	29YZ1@1|root,30KVZ@2|Bacteria,2NRNQ@2323|unclassified Bacteria	2|Bacteria	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
YHH1_k127_7397778_0	266117.Rxyl_2540	9.065e-174	563.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
YHH1_k127_7399813_3	608506.COB47_1779	4.889e-23	99.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,42GWD@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
YHH1_k127_7399813_4	945713.IALB_1763	8.887e-23	104.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.13,3.6.1.55,3.6.1.67	ko:K01515,ko:K03574,ko:K08310	ko00230,ko00790,map00230,map00790	M00126	R01054,R04638	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	NUDIX
YHH1_k127_7399813_0	1379698.RBG1_1C00001G0305	3.468e-88	299.0	COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25,6.3.2.1	ko:K01918,ko:K13799	ko00240,ko00410,ko00770,ko01100,ko01110,map00240,map00410,map00770,map01100,map01110	M00052,M00119	R00158,R00512,R01665,R02473	RC00002,RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,Pantoate_ligase
YHH1_k127_7399813_1	1540257.JQMW01000012_gene2642	1.124e-78	270.0	COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes,2482S@186801|Clostridia,36GH9@31979|Clostridiaceae	186801|Clostridia	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
YHH1_k127_7399813_2	1379698.RBG1_1C00001G0432	7.701e-33	141.0	2BV2G@1|root,32QFC@2|Bacteria,2NR6X@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7399813_5	357808.RoseRS_3735	3.607e-15	81.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH1_k127_7399813_7	1379698.RBG1_1C00001G0331	1.749e-07	55.0	COG2067@1|root,COG2067@2|Bacteria,2NPV7@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
YHH1_k127_7400090_5	237368.SCABRO_03012	2.85e-54	201.0	2ANS9@1|root,31DS7@2|Bacteria,2IZX5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7400090_2	247490.KSU1_B0648	2.49e-63	229.0	28MYQ@1|root,2ZB5K@2|Bacteria,2IZUC@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7400090_7	237368.SCABRO_03014	1.199e-48	181.0	29ZH8@1|root,30MGZ@2|Bacteria,2J0G3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7400090_0	247490.KSU1_B0650	4.428e-87	303.0	28MEN@1|root,2ZASA@2|Bacteria,2IZ1H@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7400090_3	756272.Plabr_3384	3.365e-61	221.0	2ANS9@1|root,31DS7@2|Bacteria,2IZX5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7400090_1	521674.Plim_3797	2.571e-67	240.0	28MYQ@1|root,2ZB5K@2|Bacteria,2IZUC@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7400090_6	344747.PM8797T_23686	7.393e-50	185.0	29ZH8@1|root,30MGZ@2|Bacteria,2J0G3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7400090_4	756272.Plabr_3381	6.765e-59	207.0	28MEN@1|root,2ZASA@2|Bacteria,2IZ1H@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7403637_1	1304284.L21TH_0121	3.004e-38	148.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,36DG9@31979|Clostridiaceae	186801|Clostridia	E	oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YHH1_k127_7403637_0	1397527.Q670_09385	1.199e-68	251.0	COG3391@1|root,COG5184@1|root,COG5276@1|root,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1QUHA@1224|Proteobacteria,1T1YV@1236|Gammaproteobacteria,1XS25@135619|Oceanospirillales	135619|Oceanospirillales	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
YHH1_k127_7403637_2	985255.APHJ01000054_gene2034	9.914e-33	135.0	COG3188@1|root,COG3188@2|Bacteria,4NFPY@976|Bacteroidetes,1HXS8@117743|Flavobacteriia,2P5CG@244698|Gillisia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7413700_1	1239962.C943_01492	2.07e-45	172.0	2CCNY@1|root,2Z877@2|Bacteria,4NR3D@976|Bacteroidetes	976|Bacteroidetes	E	CpeT/CpcT family (DUF1001)	-	-	-	-	-	-	-	-	-	-	-	-	CpeT
YHH1_k127_7413700_0	926562.Oweho_1016	7.43e-94	316.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1HYBS@117743|Flavobacteriia,2PA7Y@246874|Cryomorphaceae	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YHH1_k127_7428116_1	321327.CYA_0908	1.788e-63	225.0	COG2518@1|root,COG2518@2|Bacteria,1G5KC@1117|Cyanobacteria,1H0H3@1129|Synechococcus	1117|Cyanobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
YHH1_k127_7428116_0	251221.35211292	1.08e-217	704.0	COG5549@1|root,COG5549@2|Bacteria,1G2AK@1117|Cyanobacteria	1117|Cyanobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
YHH1_k127_7437578_8	983917.RGE_09900	9.683e-26	113.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	zraS	-	2.7.13.3	ko:K02668,ko:K07709,ko:K07710	ko02020,map02020	M00499,M00500,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,sCache_3_2
YHH1_k127_7437578_5	1379698.RBG1_1C00001G1427	1.86e-60	215.0	COG0231@1|root,COG0231@2|Bacteria,2NPID@2323|unclassified Bacteria	2|Bacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YHH1_k127_7437578_7	1379698.RBG1_1C00001G1425	4.592e-47	179.0	COG1039@1|root,COG1039@2|Bacteria,2NPUQ@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF3378,RNase_HII
YHH1_k127_7437578_10	1379698.RBG1_1C00001G1421	1.942e-19	92.0	COG4191@1|root,COG4191@2|Bacteria,2NQ9F@2323|unclassified Bacteria	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,MASE3,PAS_4,PAS_8,PAS_9,Response_reg
YHH1_k127_7437578_2	1211035.CD30_14055	5.062e-96	327.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli,3IX97@400634|Lysinibacillus	91061|Bacilli	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
YHH1_k127_7437578_6	1121403.AUCV01000025_gene2222	3.697e-49	183.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,2MJM4@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
YHH1_k127_7437578_0	269799.Gmet_1626	7.794e-167	533.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,43U14@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
YHH1_k127_7437578_4	1123325.JHUV01000002_gene125	2.154e-64	224.0	COG0054@1|root,COG0054@2|Bacteria,2G3YV@200783|Aquificae	200783|Aquificae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
YHH1_k127_7437578_9	1121930.AQXG01000001_gene1410	2.559e-22	101.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
YHH1_k127_7437578_1	1379698.RBG1_1C00001G0356	1.15e-126	441.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
YHH1_k127_7437578_3	1379698.RBG1_1C00001G1319	1.574e-92	311.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_7438261_19	221288.JH992900_gene319	2.268e-59	208.0	COG4288@1|root,COG4288@2|Bacteria,1G65D@1117|Cyanobacteria,1JKYE@1189|Stigonemataceae	1117|Cyanobacteria	S	Anabaena sensory rhodopsin transducer	-	-	-	-	-	-	-	-	-	-	-	-	ASRT
YHH1_k127_7438261_2	234267.Acid_5940	1.543e-234	755.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YHH1_k127_7438261_5	1379698.RBG1_1C00001G1680	1.707e-175	563.0	COG0513@1|root,COG0513@2|Bacteria,2NP0A@2323|unclassified Bacteria	2|Bacteria	JKL	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
YHH1_k127_7438261_18	195253.Syn6312_1901	2.054e-64	255.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1GHCI@1117|Cyanobacteria,1H017@1129|Synechococcus	1117|Cyanobacteria	T	TIGRFAM PAS domain S-box	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CBS,CheB_methylest,CheR,CheR_N,GAF,GAF_2,GGDEF,HATPase_c,HisKA,HisKA_2,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
YHH1_k127_7438261_12	1173028.ANKO01000022_gene5432	3.194e-102	379.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
YHH1_k127_7438261_16	502025.Hoch_0762	3.311e-76	265.0	COG1409@1|root,COG1409@2|Bacteria,1N7CQ@1224|Proteobacteria,430CA@68525|delta/epsilon subdivisions,2WW6B@28221|Deltaproteobacteria,2YWTS@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
YHH1_k127_7438261_3	589865.DaAHT2_2229	5.987e-207	660.0	COG1509@1|root,COG1509@2|Bacteria,1R6GK@1224|Proteobacteria,42PT9@68525|delta/epsilon subdivisions,2WK96@28221|Deltaproteobacteria,2MITH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM lysine 2,3-aminomutase YodO family protein	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
YHH1_k127_7438261_1	945713.IALB_0720	1.875e-240	770.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
YHH1_k127_7438261_24	1048983.EL17_01585	8.144e-12	71.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,47SPA@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM cytochrome oxidase maturation protein, cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
YHH1_k127_7438261_0	1270196.JCKI01000004_gene1192	0.0	1137.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
YHH1_k127_7438261_25	1178825.ALIH01000004_gene2889	0.0008138	45.0	2E7S7@1|root,3327D@2|Bacteria,4NUQB@976|Bacteroidetes,1I51Y@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Cbb3-type cytochrome oxidase component FixQ	ccoQ	-	-	-	-	-	-	-	-	-	-	-	FixQ
YHH1_k127_7438261_21	743722.Sph21_3529	1.485e-50	188.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
YHH1_k127_7438261_6	945713.IALB_0724	8.605e-159	514.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	ccoG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
YHH1_k127_7438261_23	945713.IALB_0725	2.179e-22	102.0	COG5456@1|root,COG5456@2|Bacteria	2|Bacteria	P	FixH	fixH	-	-	-	-	-	-	-	-	-	-	-	FixH
YHH1_k127_7438261_20	945713.IALB_0726	1.722e-56	207.0	COG2836@1|root,COG2836@2|Bacteria	2|Bacteria	K	Biogenesis protein	braZ	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2,Ferric_reduct
YHH1_k127_7438261_15	761193.Runsl_1977	1.284e-94	326.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
YHH1_k127_7438261_4	1047013.AQSP01000104_gene1419	1.666e-201	637.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_7438261_10	1237149.C900_03827	7.194e-125	428.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH1_k127_7438261_9	1047013.AQSP01000104_gene1418	3.082e-139	454.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH1_k127_7438261_11	1121930.AQXG01000008_gene207	1.474e-105	347.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,1INQS@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_7438261_8	1279009.ADICEAN_02125	3.091e-148	498.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47MF5@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH1_k127_7438261_14	1047013.AQSP01000140_gene2509	7.473e-95	340.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_7438261_13	929703.KE386491_gene3280	2.352e-101	334.0	COG1136@1|root,COG1136@2|Bacteria,4NEC5@976|Bacteroidetes,47N33@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH1_k127_7438261_7	1185876.BN8_01431	1.036e-148	500.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47MF5@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,HTH_18,MacB_PCD
YHH1_k127_7438261_17	945713.IALB_2739	3.153e-67	230.0	COG0114@1|root,COG0114@2|Bacteria	2|Bacteria	C	fumarate hydratase activity	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
YHH1_k127_7450692_0	933262.AXAM01000005_gene2497	7.838e-101	334.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,42N3R@68525|delta/epsilon subdivisions,2WJDN@28221|Deltaproteobacteria,2MIW5@213118|Desulfobacterales	28221|Deltaproteobacteria	N	flagellar basal-body rod protein FlgG	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
YHH1_k127_7450692_1	696369.KI912183_gene203	4.857e-36	146.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,24C2V@186801|Clostridia,261UD@186807|Peptococcaceae	186801|Clostridia	N	basal body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
YHH1_k127_7450692_2	1379698.RBG1_1C00001G0594	8.528e-23	112.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin_3,DUF11,FlgD_ig
YHH1_k127_7450769_7	330214.NIDE4355	8.536e-10	63.0	COG0436@1|root,COG0436@2|Bacteria,3J0EV@40117|Nitrospirae	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_7450769_3	28072.Nos7524_0700	2.326e-45	172.0	COG4405@1|root,COG4405@2|Bacteria,1GE0T@1117|Cyanobacteria	1117|Cyanobacteria	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
YHH1_k127_7450769_0	219305.MCAG_05245	9.848e-135	437.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4DAXK@85008|Micromonosporales	201174|Actinobacteria	EK	Cystathionine beta-synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH1_k127_7450769_5	521098.Aaci_1293	1.998e-21	104.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4HFUM@91061|Bacilli,278FY@186823|Alicyclobacillaceae	91061|Bacilli	S	Belongs to the multicopper oxidase YfiH RL5 family	ylmD	GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
YHH1_k127_7450769_2	1379698.RBG1_1C00001G0718	9.646e-82	288.0	COG0612@1|root,COG0612@2|Bacteria,2NPE5@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_7450769_1	1379698.RBG1_1C00001G0719	7.304e-121	402.0	COG0612@1|root,COG0612@2|Bacteria,2NP50@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_7450769_6	1229780.BN381_130143	8.21e-10	62.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7466852_0	1123366.TH3_19014	3.055e-42	162.0	COG0504@1|root,COG0504@2|Bacteria,1QBV2@1224|Proteobacteria	1224|Proteobacteria	F	CTP synthase	pyrG2	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YHH1_k127_7466852_1	1123301.KB904188_gene658	3.94e-41	164.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YHH1_k127_7466852_2	1423754.BALY01000004_gene1532	1.445e-07	61.0	COG4116@1|root,COG4116@2|Bacteria,1TTVM@1239|Firmicutes,4I4A3@91061|Bacilli,3F4YS@33958|Lactobacillaceae	91061|Bacilli	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
YHH1_k127_7468830_0	234267.Acid_1198	8.164e-202	644.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
YHH1_k127_7469305_5	247634.GPB2148_3226	5.056e-52	197.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
YHH1_k127_7469305_6	1121405.dsmv_1217	1.122e-50	184.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
YHH1_k127_7469305_7	521011.Mpal_0671	1.304e-46	177.0	arCOG02576@1|root,arCOG02576@2157|Archaea,2XZNM@28890|Euryarchaeota,2N9WU@224756|Methanomicrobia	224756|Methanomicrobia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
YHH1_k127_7469305_0	247490.KSU1_C0602	3.26e-145	470.0	COG2133@1|root,COG2133@2|Bacteria,2IXAF@203682|Planctomycetes	203682|Planctomycetes	G	glucose sorbosone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	DUF1080,GSDH,SGL
YHH1_k127_7469305_2	1121920.AUAU01000001_gene2268	1.264e-76	271.0	COG2864@1|root,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
YHH1_k127_7469305_3	945713.IALB_1306	1.409e-60	222.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
YHH1_k127_7469305_4	880072.Desac_0068	6.172e-54	201.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WR70@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7469305_1	1125863.JAFN01000001_gene1695	1.643e-78	282.0	COG3005@1|root,COG3005@2|Bacteria,1RJ3G@1224|Proteobacteria,42ST3@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_NNT,Cytochrome_C7
YHH1_k127_7470243_1	1121459.AQXE01000002_gene1342	9.845e-115	382.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42PJQ@68525|delta/epsilon subdivisions,2WKR4@28221|Deltaproteobacteria,2M7SH@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	iAF987.Gmet_3470	CBS,Voltage_CLC
YHH1_k127_7470243_0	1379698.RBG1_1C00001G1659	1.104e-121	411.0	COG2812@1|root,COG2812@2|Bacteria,2NNK7@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
YHH1_k127_7474428_2	445972.ANACOL_03059	0.000222	48.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Nitroreductase
YHH1_k127_7474428_0	525904.Tter_1847	2.107e-34	147.0	COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_7474428_1	251221.35211629	4.643e-23	111.0	COG1216@1|root,COG1216@2|Bacteria,1FZX3@1117|Cyanobacteria	1117|Cyanobacteria	KT	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_7500159_0	1379698.RBG1_1C00001G1092	1.094e-178	585.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
YHH1_k127_7500159_1	1121430.JMLG01000005_gene779	2.301e-148	481.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,2609N@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YHH1_k127_7500159_2	926567.TheveDRAFT_1038	6.542e-41	156.0	COG0041@1|root,COG0041@2|Bacteria,3TB8R@508458|Synergistetes	508458|Synergistetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YHH1_k127_7500159_4	1356852.N008_06150	2.538e-11	74.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,47XPU@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
YHH1_k127_7500159_3	1123508.JH636453_gene5800	8.553e-18	97.0	COG3391@1|root,COG3391@2|Bacteria,2J08H@203682|Planctomycetes	203682|Planctomycetes	J	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH1_k127_7509176_1	515635.Dtur_1286	1.711e-95	331.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
YHH1_k127_7509176_7	1379698.RBG1_1C00001G0373	2.286e-18	99.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane
YHH1_k127_7509176_6	755731.Clo1100_0050	2.2e-26	114.0	COG1528@1|root,COG1528@2|Bacteria,1V1BJ@1239|Firmicutes,24FUF@186801|Clostridia,36IYC@31979|Clostridiaceae	186801|Clostridia	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
YHH1_k127_7509176_5	1463856.JOHY01000034_gene2310	7.719e-69	243.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria	201174|Actinobacteria	GK	polyphosphate glucokinase	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH1_k127_7509176_4	1295642.H839_02601	5.164e-69	252.0	COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1WFIP@129337|Geobacillus	91061|Bacilli	O	CAAX prenyl protease N-terminal, five membrane helices	yhfN	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
YHH1_k127_7509176_3	1379698.RBG1_1C00001G0290	1.728e-79	296.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
YHH1_k127_7509176_0	1379698.RBG1_1C00001G0290	1.871e-104	367.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
YHH1_k127_7509176_2	1379698.RBG1_1C00001G0290	5.503e-89	320.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
YHH1_k127_7513994_3	401526.TcarDRAFT_1264	0.0006373	44.0	COG1629@1|root,COG4771@2|Bacteria,1UK22@1239|Firmicutes,4H36M@909932|Negativicutes	909932|Negativicutes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
YHH1_k127_7513994_1	477974.Daud_0985	1.659e-28	123.0	COG0746@1|root,COG1763@1|root,COG0746@2|Bacteria,COG1763@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia,262DJ@186807|Peptococcaceae	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
YHH1_k127_7513994_2	246194.CHY_0868	2.127e-20	98.0	COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,24IYN@186801|Clostridia,42GXT@68295|Thermoanaerobacterales	186801|Clostridia	H	Molybdopterin-guanine dinucleotide biosynthesis protein B	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
YHH1_k127_7513994_0	1319815.HMPREF0202_00951	1.698e-31	134.0	COG1526@1|root,COG1526@2|Bacteria,37B1Q@32066|Fusobacteria	32066|Fusobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
YHH1_k127_7533806_1	1173025.GEI7407_2591	1.175e-42	162.0	COG4221@1|root,COG4221@2|Bacteria,1G182@1117|Cyanobacteria,1H965@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
YHH1_k127_7533806_0	555779.Dthio_PD3396	1.044e-43	172.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH1_k127_7533806_2	1379698.RBG1_1C00001G1702	6.646e-32	132.0	COG1595@1|root,COG1595@2|Bacteria,2NR5Q@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YHH1_k127_7553396_3	359.CN09_29750	7.977e-05	49.0	COG4113@1|root,COG4113@2|Bacteria,1N96B@1224|Proteobacteria,2UDE1@28211|Alphaproteobacteria,4BGJI@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH1_k127_7553396_1	1121918.ARWE01000001_gene3108	3.541e-32	128.0	COG0580@1|root,COG0580@2|Bacteria,1MZ47@1224|Proteobacteria	1224|Proteobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
YHH1_k127_7553396_2	1121875.KB907549_gene1996	4.892e-16	80.0	COG1063@1|root,COG1063@2|Bacteria,4P3W3@976|Bacteroidetes	976|Bacteroidetes	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
YHH1_k127_7553396_0	1121405.dsmv_0802	1.73e-53	190.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2WRUT@28221|Deltaproteobacteria,2MNXP@213118|Desulfobacterales	28221|Deltaproteobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YHH1_k127_7563893_1	667014.Thein_1023	4.663e-45	168.0	COG0388@1|root,COG0615@1|root,COG0388@2|Bacteria,COG0615@2|Bacteria,2GHDJ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	IM	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,CTP_transf_like
YHH1_k127_7563893_0	1379698.RBG1_1C00001G1507	7.044e-62	220.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
YHH1_k127_7614614_12	1120944.JONS01000001_gene1942	9.601e-32	143.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4D3IX@85005|Actinomycetales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
YHH1_k127_7614614_1	1379698.RBG1_1C00001G0287	3.643e-147	486.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
YHH1_k127_7614614_14	518766.Rmar_2626	1.096e-21	110.0	COG0729@1|root,COG0729@2|Bacteria	2|Bacteria	M	surface antigen	-	-	-	ko:K07277,ko:K07278	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,Peptidase_S74
YHH1_k127_7614614_10	1379698.RBG1_1C00001G0634	8.496e-45	170.0	COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
YHH1_k127_7614614_8	1382359.JIAL01000001_gene1199	1.982e-50	203.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,SpoIIE
YHH1_k127_7614614_11	1379698.RBG1_1C00001G0633	9.778e-35	138.0	COG2172@1|root,COG2172@2|Bacteria,2NQ1S@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma regulatory factor (Ser Thr protein kinase)	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,SpoIIE
YHH1_k127_7614614_9	1379698.RBG1_1C00001G0632	1.201e-46	170.0	COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
YHH1_k127_7614614_2	247490.KSU1_C0701	7.871e-126	416.0	COG0577@1|root,COG0577@2|Bacteria,2IY2P@203682|Planctomycetes	203682|Planctomycetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX,MacB_PCD
YHH1_k127_7614614_7	243231.GSU0496	5.972e-88	306.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,43SP7@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YHH1_k127_7614614_13	926561.KB900617_gene1659	7.327e-25	121.0	COG4206@1|root,COG4206@2|Bacteria,1V287@1239|Firmicutes,24SUD@186801|Clostridia,3WB9E@53433|Halanaerobiales	186801|Clostridia	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
YHH1_k127_7614614_15	1304284.L21TH_0309	5.49e-10	65.0	2EVAK@1|root,33NR6@2|Bacteria,1VMGM@1239|Firmicutes,24V68@186801|Clostridia,36P4Y@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7614614_4	118163.Ple7327_4457	3.284e-120	395.0	COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria,3VIG5@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH1_k127_7614614_5	448385.sce3387	6.511e-120	406.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7614614_0	1379698.RBG1_1C00001G0618	1.698e-208	670.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	yuxL	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
YHH1_k127_7614614_6	234267.Acid_3687	2.684e-104	367.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria	57723|Acidobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
YHH1_k127_7614614_3	234267.Acid_4926	3.017e-121	398.0	COG1063@1|root,COG1063@2|Bacteria,3Y7C2@57723|Acidobacteria	57723|Acidobacteria	E	Alcohol dehydrogenase GroES-associated	-	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
YHH1_k127_7623525_0	517418.Ctha_1181	4.037e-14	85.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
YHH1_k127_7623525_1	425104.Ssed_3642	6.159e-08	60.0	COG3911@1|root,COG3911@2|Bacteria,1RBSG@1224|Proteobacteria,1S31D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
YHH1_k127_7629101_2	273068.TTE0628	2.942e-52	193.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,42GDM@68295|Thermoanaerobacterales	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
YHH1_k127_7629101_0	187272.Mlg_2286	1.799e-250	798.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1WWYF@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH1_k127_7629101_4	1089544.KB912942_gene4067	0.0008989	42.0	COG0582@1|root,COG0582@2|Bacteria,2IHIW@201174|Actinobacteria,4E2P0@85010|Pseudonocardiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
YHH1_k127_7629101_1	234267.Acid_2488	2.915e-54	200.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH1_k127_7629101_3	1449050.JNLE01000003_gene3021	1.326e-46	176.0	COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,25DKM@186801|Clostridia,36IAZ@31979|Clostridiaceae	186801|Clostridia	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
YHH1_k127_7638133_4	547042.BACCOPRO_01603	0.0009133	46.0	2EZXA@1|root,33T1J@2|Bacteria,4P0CW@976|Bacteroidetes,2FQDD@200643|Bacteroidia,4ARKU@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7638133_0	272123.Anacy_1177	1.529e-22	102.0	COG1413@1|root,COG1413@2|Bacteria,1GJMP@1117|Cyanobacteria,1HS38@1161|Nostocales	1117|Cyanobacteria	C	Protein of unknown function (DUF1186)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1186
YHH1_k127_7638133_2	1298598.JCM21714_2240	2.079e-10	64.0	COG3012@1|root,COG3012@2|Bacteria,1V6ZS@1239|Firmicutes,4HWAS@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1186)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1186,SEC-C
YHH1_k127_7638133_1	941449.dsx2_1040	7.686e-20	94.0	COG4974@1|root,COG4974@2|Bacteria,1R20K@1224|Proteobacteria,43DCZ@68525|delta/epsilon subdivisions,2X8IX@28221|Deltaproteobacteria,2M8WV@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YHH1_k127_7638133_3	1121355.KB903379_gene745	6.117e-08	57.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YHH1_k127_7643008_0	1122917.KB899664_gene3134	3.86e-73	251.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,26RVY@186822|Paenibacillaceae	91061|Bacilli	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
YHH1_k127_7643008_1	744985.HIMB59_00002290	9.566e-30	121.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2UBQB@28211|Alphaproteobacteria,4BQZ0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
YHH1_k127_7666665_0	1379698.RBG1_1C00001G0712	9.482e-129	422.0	COG0612@1|root,COG0612@2|Bacteria,2NQPM@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_7666665_1	574375.BAGA_08090	4.15e-44	178.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,1ZAZE@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	PPC,Peptidase_S8
YHH1_k127_7666665_2	504728.K649_03590	5.493e-20	93.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,TPR_10,TPR_12,TPR_7,TPR_8
YHH1_k127_7683112_5	671143.DAMO_0822	1.336e-07	58.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
YHH1_k127_7683112_0	1191523.MROS_2798	0.0	1223.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
YHH1_k127_7683112_3	861299.J421_1362	6.091e-57	213.0	COG2972@1|root,COG2972@2|Bacteria,1ZUX6@142182|Gemmatimonadetes	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
YHH1_k127_7683112_2	378806.STAUR_8302	2.753e-76	264.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria,2YVX5@29|Myxococcales	28221|Deltaproteobacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
YHH1_k127_7683112_1	313606.M23134_00255	2.149e-129	433.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,47RAA@768503|Cytophagia	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
YHH1_k127_7683112_4	1254432.SCE1572_15775	3.549e-10	73.0	COG3391@1|root,COG5184@1|root,COG5276@1|root,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2YV9Z@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
YHH1_k127_7716228_1	857087.Metme_3907	2.518e-09	67.0	COG5652@1|root,COG5652@2|Bacteria,1QUYG@1224|Proteobacteria,1T5BX@1236|Gammaproteobacteria,1XGA1@135618|Methylococcales	135618|Methylococcales	S	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
YHH1_k127_7716228_0	1131553.JIBI01000008_gene1280	1.949e-19	93.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,2VKT7@28216|Betaproteobacteria,3727E@32003|Nitrosomonadales	28216|Betaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH1_k127_7739337_3	1379698.RBG1_1C00001G1457	1.7e-116	386.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YHH1_k127_7739337_1	1379698.RBG1_1C00001G1458	8.648e-133	433.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YHH1_k127_7739337_2	555088.DealDRAFT_3078	2.799e-120	392.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,42JQM@68298|Syntrophomonadaceae	186801|Clostridia	C	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
YHH1_k127_7739337_0	1379698.RBG1_1C00001G1459	2.213e-164	526.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
YHH1_k127_7739337_4	1506583.JQJY01000005_gene2042	2.165e-19	96.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia,2NWCZ@237|Flavobacterium	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
YHH1_k127_7742053_1	1121904.ARBP01000012_gene1193	4.702e-35	141.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH1_k127_7742053_2	1499967.BAYZ01000025_gene299	9.115e-29	134.0	COG4733@1|root,COG5276@1|root,COG4733@2|Bacteria,COG5276@2|Bacteria,2NS5M@2323|unclassified Bacteria	2|Bacteria	P	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,Phage-tail_3,TIG,fn3
YHH1_k127_7742053_0	290512.Paes_0204	2.577e-57	223.0	COG1262@1|root,COG1680@1|root,COG1262@2|Bacteria,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,Fib_succ_major,TIR_2
YHH1_k127_7746165_0	700598.Niako_1197	5.302e-40	161.0	2DBXV@1|root,2ZBR7@2|Bacteria,4NNEK@976|Bacteroidetes	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7746165_1	1232683.ADIMK_1419	1.109e-10	67.0	2C5U9@1|root,2Z9NJ@2|Bacteria,1R6D0@1224|Proteobacteria,1S1VT@1236|Gammaproteobacteria,46CSB@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
YHH1_k127_7774401_7	1137268.AZXF01000018_gene577	4.224e-32	143.0	29WHJ@1|root,30I3Q@2|Bacteria,2ITG0@201174|Actinobacteria	201174|Actinobacteria	S	Thiol-activated cytolysin	-	-	-	-	-	-	-	-	-	-	-	-	Thiol_cytolysin
YHH1_k127_7774401_11	196367.JNFG01000020_gene4778	2.168e-05	54.0	COG1670@1|root,COG1670@2|Bacteria,1RFBQ@1224|Proteobacteria	1224|Proteobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YHH1_k127_7774401_12	6500.XP_005096244.1	2.28e-05	50.0	COG0484@1|root,KOG0715@2759|Eukaryota,38H0N@33154|Opisthokonta,3BAQ9@33208|Metazoa,3CZDG@33213|Bilateria	33208|Metazoa	O	heat shock protein binding	DNAJA3	GO:0000002,GO:0000122,GO:0001775,GO:0001776,GO:0001932,GO:0001933,GO:0001941,GO:0001959,GO:0001960,GO:0002119,GO:0002164,GO:0002260,GO:0002376,GO:0002520,GO:0002521,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002696,GO:0003674,GO:0005102,GO:0005113,GO:0005126,GO:0005133,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006264,GO:0006355,GO:0006357,GO:0006457,GO:0006469,GO:0006725,GO:0006807,GO:0006915,GO:0006919,GO:0006924,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007166,GO:0007224,GO:0007264,GO:0007275,GO:0007528,GO:0007568,GO:0007569,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008285,GO:0009058,GO:0009059,GO:0009295,GO:0009790,GO:0009791,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010556,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010941,GO:0010942,GO:0010950,GO:0010951,GO:0010952,GO:0012501,GO:0016020,GO:0016043,GO:0019219,GO:0019220,GO:0019222,GO:0019897,GO:0019898,GO:0019899,GO:0019900,GO:0019901,GO:0022407,GO:0022409,GO:0023051,GO:0023052,GO:0023057,GO:0030097,GO:0030098,GO:0030154,GO:0030155,GO:0030162,GO:0030217,GO:0030234,GO:0030544,GO:0030695,GO:0030971,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031347,GO:0031348,GO:0031396,GO:0031398,GO:0031399,GO:0031400,GO:0031401,GO:0031594,GO:0031647,GO:0031974,GO:0032042,GO:0032088,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032944,GO:0032946,GO:0033036,GO:0033077,GO:0033673,GO:0034097,GO:0034341,GO:0034613,GO:0034641,GO:0034645,GO:0035556,GO:0042102,GO:0042110,GO:0042127,GO:0042129,GO:0042221,GO:0042325,GO:0042326,GO:0042592,GO:0042645,GO:0042981,GO:0043029,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043113,GO:0043122,GO:0043124,GO:0043154,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043280,GO:0043281,GO:0043433,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044464,GO:0045087,GO:0045088,GO:0045202,GO:0045211,GO:0045321,GO:0045785,GO:0045824,GO:0045859,GO:0045861,GO:0045862,GO:0045892,GO:0045934,GO:0045936,GO:0046483,GO:0046649,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048869,GO:0048872,GO:0050670,GO:0050671,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050794,GO:0050808,GO:0050821,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051059,GO:0051082,GO:0051090,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051251,GO:0051252,GO:0051253,GO:0051336,GO:0051338,GO:0051345,GO:0051346,GO:0051348,GO:0051641,GO:0051668,GO:0051716,GO:0052547,GO:0052548,GO:0060255,GO:0060330,GO:0060331,GO:0060334,GO:0060336,GO:0060548,GO:0060589,GO:0060759,GO:0060761,GO:0061024,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070227,GO:0070231,GO:0070663,GO:0070665,GO:0070727,GO:0071340,GO:0071704,GO:0071840,GO:0071887,GO:0071944,GO:0072657,GO:0080090,GO:0080134,GO:0090304,GO:0097060,GO:0098590,GO:0098772,GO:0098794,GO:0099173,GO:1901360,GO:1901576,GO:1902531,GO:1902532,GO:1902679,GO:1903037,GO:1903039,GO:1903320,GO:1903322,GO:1903506,GO:1903507,GO:1990782,GO:2000112,GO:2000113,GO:2000116,GO:2000117,GO:2001056,GO:2001141	-	ko:K09504	ko05203,map05203	-	-	-	ko00000,ko00001,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH1_k127_7774401_8	237368.SCABRO_02485	3.397e-31	129.0	COG0745@1|root,COG0745@2|Bacteria	237368.SCABRO_02485|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7774401_1	1499967.BAYZ01000059_gene4782	1.403e-116	402.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HAMP,HATPase_c,HisKA,PAS,dCache_3
YHH1_k127_7774401_6	1123278.KB893620_gene3482	1.065e-32	145.0	COG0451@1|root,COG0451@2|Bacteria,4NI6B@976|Bacteroidetes,47UHB@768503|Cytophagia	976|Bacteroidetes	GM	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YHH1_k127_7774401_9	1121428.DESHY_60146___1	3.687e-24	113.0	COG3058@1|root,COG3058@2|Bacteria,1VD22@1239|Firmicutes,24P6T@186801|Clostridia,262GU@186807|Peptococcaceae	186801|Clostridia	O	Necessary for formate dehydrogenase activity	-	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
YHH1_k127_7774401_4	439235.Dalk_1854	2.94e-64	224.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria,2MIG4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
YHH1_k127_7774401_0	439235.Dalk_1854	0.0	1127.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria,2MIG4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
YHH1_k127_7774401_3	439235.Dalk_1855	4.466e-83	285.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NS2@68525|delta/epsilon subdivisions,2WMA0@28221|Deltaproteobacteria,2MN9Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	fdnH	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,NrfD
YHH1_k127_7774401_2	204669.Acid345_2602	3.871e-100	340.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
YHH1_k127_7774401_10	290397.Adeh_2423	2.906e-19	101.0	29X07@1|root,30ING@2|Bacteria,1PDK6@1224|Proteobacteria,43E67@68525|delta/epsilon subdivisions,2WZUQ@28221|Deltaproteobacteria,2Z2SP@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7774401_5	1121396.KB893056_gene2663	1.794e-63	241.0	COG4206@1|root,COG4206@2|Bacteria,1QVD1@1224|Proteobacteria,43BSV@68525|delta/epsilon subdivisions,2WK8I@28221|Deltaproteobacteria,2MJIT@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
YHH1_k127_7796630_1	1379698.RBG1_1C00001G1223	5.649e-122	402.0	COG0665@1|root,COG0665@2|Bacteria,2NP0X@2323|unclassified Bacteria	2|Bacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
YHH1_k127_7796630_0	1379698.RBG1_1C00001G0175	2.022e-136	462.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,2NRE7@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02022,ko:K16922,ko:K20345	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002,ko02000	3.A.1.112,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,PqqD
YHH1_k127_7796630_2	696747.NIES39_C02780	3.354e-12	78.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1HA36@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,TPR_12,TPR_7,TPR_8
YHH1_k127_7800331_1	1379698.RBG1_1C00001G0118	2.029e-73	252.0	29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7800331_0	1379698.RBG1_1C00001G0119	3.242e-114	382.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7803505_3	1122915.AUGY01000022_gene6721	3.015e-28	127.0	COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,4HCCZ@91061|Bacilli,26RZM@186822|Paenibacillaceae	91061|Bacilli	N	Belongs to the bacterial flagellin family	flgL	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
YHH1_k127_7803505_5	1379698.RBG1_1C00001G1112	2.002e-18	89.0	COG1551@1|root,COG1551@2|Bacteria,2NQ31@2323|unclassified Bacteria	2|Bacteria	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563,ko:K13626	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko02035,ko03019	-	-	-	CsrA
YHH1_k127_7803505_0	635013.TherJR_2798	3.077e-94	325.0	COG1256@1|root,COG4786@1|root,COG1256@2|Bacteria,COG4786@2|Bacteria,1TPXH@1239|Firmicutes,249PE@186801|Clostridia,260KA@186807|Peptococcaceae	186801|Clostridia	N	TIGRFAM Flagellar hook-associated protein, FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
YHH1_k127_7803505_6	509191.AEDB02000049_gene4382	1.275e-08	62.0	COG3418@1|root,COG3418@2|Bacteria,1VF67@1239|Firmicutes,24SF3@186801|Clostridia,3WPHI@541000|Ruminococcaceae	186801|Clostridia	NOU	FlgN protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
YHH1_k127_7803505_2	1313304.CALK_0177	8.841e-37	151.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	yjbJ	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,Rod-binding,SLT
YHH1_k127_7803505_1	1125863.JAFN01000001_gene780	8.714e-91	311.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,42MAU@68525|delta/epsilon subdivisions,2WK22@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
YHH1_k127_7803505_4	926692.AZYG01000011_gene1104	4.997e-26	115.0	COG2063@1|root,COG2063@2|Bacteria,1V4W8@1239|Firmicutes,24QQ1@186801|Clostridia,3WBTW@53433|Halanaerobiales	186801|Clostridia	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
YHH1_k127_7803505_7	316067.Geob_0629	1.819e-08	61.0	COG1261@1|root,COG1261@2|Bacteria,1QQIM@1224|Proteobacteria,42V31@68525|delta/epsilon subdivisions,2WRK7@28221|Deltaproteobacteria,43UW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
YHH1_k127_7804308_0	338969.Rfer_1105	7.426e-40	166.0	COG4099@1|root,COG4099@2|Bacteria,1Q9H4@1224|Proteobacteria,2W2SQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
YHH1_k127_7804308_2	313612.L8106_12375	1.666e-14	86.0	COG4188@1|root,COG4188@2|Bacteria,1FZWS@1117|Cyanobacteria,1H817@1150|Oscillatoriales	1117|Cyanobacteria	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DUF1400,Hydrolase_4,PAF-AH_p_II
YHH1_k127_7804308_1	1157490.EL26_02245	9.146e-30	121.0	COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,4HEJ3@91061|Bacilli	91061|Bacilli	S	homoserine kinase type II (protein kinase fold)	yerI	-	-	-	-	-	-	-	-	-	-	-	APH
YHH1_k127_7826091_0	760192.Halhy_4037	1.984e-34	139.0	COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Fn3_assoc,Metallophos,PA14
YHH1_k127_7826091_1	1191523.MROS_0520	2.604e-25	119.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Porin_2
YHH1_k127_7862807_4	1121472.AQWN01000014_gene620	1.314e-61	220.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,25ZXM@186807|Peptococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
YHH1_k127_7862807_5	1388763.O165_023590	8.213e-08	64.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,1RY0T@1236|Gammaproteobacteria,1YWVG@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,PQQ_2
YHH1_k127_7862807_1	747365.Thena_0240	1.999e-87	302.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,42I94@68295|Thermoanaerobacterales	186801|Clostridia	E	COGs COG0683 ABC-type branched-chain amino acid transport systems periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YHH1_k127_7862807_0	643562.Daes_3023	3.598e-90	305.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42N64@68525|delta/epsilon subdivisions,2WJ73@28221|Deltaproteobacteria,2M7RI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
YHH1_k127_7862807_3	1121035.AUCH01000009_gene813	5.198e-72	257.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,2KU9H@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
YHH1_k127_7862807_2	1121468.AUBR01000023_gene2737	2.064e-83	284.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,42FCE@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
YHH1_k127_7876748_0	1408473.JHXO01000011_gene3210	4.925e-139	457.0	COG0421@1|root,COG0421@2|Bacteria,4NTHI@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7876748_1	1408473.JHXO01000006_gene1092	2.792e-74	256.0	COG0388@1|root,COG0388@2|Bacteria,4PPAR@976|Bacteroidetes,2G14Y@200643|Bacteroidia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
YHH1_k127_7892986_2	1379698.RBG1_1C00001G1821	8.678e-21	102.0	COG0095@1|root,COG0095@2|Bacteria,2NPP1@2323|unclassified Bacteria	2|Bacteria	H	Biotin/lipoate A/B protein ligase family	lipM	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YHH1_k127_7892986_0	1379698.RBG1_1C00001G0933	1.686e-119	419.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02584,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat
YHH1_k127_7892986_1	868131.MSWAN_0651	3.879e-95	324.0	COG2006@1|root,arCOG02447@2157|Archaea,2XW1U@28890|Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S ferredoxin iron-sulfur binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_7
YHH1_k127_7893180_3	1121943.KB900010_gene2721	1.156e-12	71.0	2E3GE@1|root,32YF6@2|Bacteria,1N7MX@1224|Proteobacteria,1SGRX@1236|Gammaproteobacteria,1XQFY@135619|Oceanospirillales	135619|Oceanospirillales	S	Uncharacterized protein conserved in bacteria (DUF2188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2188
YHH1_k127_7893180_1	58123.JOFJ01000006_gene138	6.142e-39	157.0	COG0500@1|root,COG2226@2|Bacteria,2I35J@201174|Actinobacteria,4EIVJ@85012|Streptosporangiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH1_k127_7893180_2	1250232.JQNJ01000001_gene1256	1.665e-18	89.0	2ESJ3@1|root,33K3T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
YHH1_k127_7893180_0	1226322.HMPREF1545_02074	0.0	1210.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,2N6CX@216572|Oscillospiraceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH1_k127_7893180_4	582899.Hden_3088	7.387e-08	59.0	2EI58@1|root,33BWK@2|Bacteria,1NMVP@1224|Proteobacteria,2UKIB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7916142_0	269799.Gmet_2011	1.656e-56	204.0	COG2227@1|root,COG2227@2|Bacteria,1NBIU@1224|Proteobacteria,43CAM@68525|delta/epsilon subdivisions,2WWNH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7916142_1	1163617.SCD_n02970	4.26e-41	154.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VJVY@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_7916606_0	671143.DAMO_0350	1.543e-50	188.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7916606_1	330214.NIDE2492	1.862e-41	162.0	2ANS9@1|root,31DS7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7916606_2	1121468.AUBR01000064_gene937	8.849e-19	89.0	COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,24F1Y@186801|Clostridia,42G35@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YHH1_k127_7943185_4	1267533.KB906738_gene2313	2.349e-27	113.0	COG1956@1|root,COG1956@2|Bacteria,3Y4UF@57723|Acidobacteria,2JJHH@204432|Acidobacteriia	204432|Acidobacteriia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
YHH1_k127_7943185_5	573370.DMR_45810	2.714e-07	64.0	COG4249@1|root,COG4412@1|root,COG4249@2|Bacteria,COG4412@2|Bacteria,1MWWV@1224|Proteobacteria,42S3D@68525|delta/epsilon subdivisions,2WNYK@28221|Deltaproteobacteria,2MAJY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Peptidase C13 family	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C13
YHH1_k127_7943185_0	247490.KSU1_C0714	2.53e-134	462.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
YHH1_k127_7943185_2	1192034.CAP_8119	3.939e-41	175.0	COG5184@1|root,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2YV9Z@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
YHH1_k127_7943185_1	243231.GSU3151	5.152e-44	167.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria,43UQJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7943185_3	1408433.JHXV01000005_gene2349	1.11e-32	146.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia,2PBIN@246874|Cryomorphaceae	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
YHH1_k127_7944851_1	224325.AF_1319	3.358e-16	88.0	arCOG07525@1|root,arCOG07525@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7944851_0	283942.IL0625	8.589e-71	260.0	COG2159@1|root,COG2159@2|Bacteria,1NAC7@1224|Proteobacteria	1224|Proteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
YHH1_k127_7944851_2	56780.SYN_02434	2.482e-07	55.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.5.1.106	ko:K15357	ko00760,ko01120,map00760,map01120	M00622	R09126	RC00323,RC02431	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_3,Abhydrolase_6,Hydrolase_4
YHH1_k127_7954459_7	1173264.KI913949_gene37	1.111e-23	103.0	COG1791@1|root,COG1791@2|Bacteria,1G274@1117|Cyanobacteria	1117|Cyanobacteria	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
YHH1_k127_7954459_2	1173264.KI913949_gene709	1.15e-51	190.0	COG0235@1|root,COG0235@2|Bacteria,1G2EA@1117|Cyanobacteria,1H8JN@1150|Oscillatoriales	1117|Cyanobacteria	E	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)	mtnB	-	4.2.1.109	ko:K08964	ko00270,ko01100,map00270,map01100	M00034	R07392	RC01939	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
YHH1_k127_7954459_0	1121403.AUCV01000013_gene4008	1.953e-103	353.0	COG5492@1|root,COG5492@2|Bacteria,1QY8X@1224|Proteobacteria,43CAR@68525|delta/epsilon subdivisions,2X7M8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7954459_4	234267.Acid_5496	3.416e-44	166.0	2C7E0@1|root,330TX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7954459_5	1298920.KI911353_gene3042	2.55e-32	132.0	COG3315@1|root,COG3315@2|Bacteria,1TR1Q@1239|Firmicutes,24BWW@186801|Clostridia,223TT@1506553|Lachnoclostridium	186801|Clostridia	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
YHH1_k127_7954459_1	521011.Mpal_0492	7.181e-86	295.0	COG1584@1|root,arCOG03176@2157|Archaea,2XWNC@28890|Euryarchaeota,2N9MY@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM GPR1 FUN34 yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
YHH1_k127_7954459_8	1202532.FF52_19655	4.928e-07	59.0	COG4232@1|root,COG4232@2|Bacteria,4NQYR@976|Bacteroidetes,1IAS9@117743|Flavobacteriia,2NXYS@237|Flavobacterium	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
YHH1_k127_7954459_3	204669.Acid345_1709	1.342e-50	195.0	COG0491@1|root,COG0491@2|Bacteria,3Y4D7@57723|Acidobacteria,2JKB5@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH1_k127_7954459_6	1279009.ADICEAN_02760	1.083e-24	110.0	COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,47NZT@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH1_k127_7954459_9	706587.Desti_0073	9.081e-06	50.0	COG1024@1|root,COG1024@2|Bacteria,1N2V7@1224|Proteobacteria,42UXR@68525|delta/epsilon subdivisions,2WQCT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YHH1_k127_795583_0	1379698.RBG1_1C00001G1501	9.085e-182	581.0	COG0439@1|root,COG0439@2|Bacteria,2NNWM@2323|unclassified Bacteria	2|Bacteria	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YHH1_k127_795583_1	1379698.RBG1_1C00001G1500	1.834e-46	170.0	COG0509@1|root,COG0509@2|Bacteria,2NPMR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
YHH1_k127_7957538_5	1121324.CLIT_11c00630	8.246e-77	264.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_7957538_1	518766.Rmar_1442	1.188e-112	377.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1FIY8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_7957538_2	518766.Rmar_1441	4.895e-102	347.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_7957538_3	518766.Rmar_1440	3.145e-90	310.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
YHH1_k127_7957538_4	1227360.C176_19199	1.105e-82	289.0	COG4335@1|root,COG4335@2|Bacteria,1TRE4@1239|Firmicutes,4HA0G@91061|Bacilli	91061|Bacilli	L	DNA alkylation repair enzyme	yhaZ	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YHH1_k127_7957538_0	1341151.ASZU01000026_gene1167	4.55e-167	546.0	COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,27AXH@186824|Thermoactinomycetaceae	91061|Bacilli	E	Peptidase family M3	pepF2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
YHH1_k127_7957538_9	517418.Ctha_1876	2.018e-15	84.0	COG4577@1|root,COG4577@2|Bacteria,1FFCZ@1090|Chlorobi	1090|Chlorobi	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
YHH1_k127_7957538_7	1123371.ATXH01000002_gene367	1.252e-63	245.0	COG3829@1|root,COG3829@2|Bacteria,2GIBW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
YHH1_k127_7957538_10	985054.JQEZ01000001_gene1879	4.683e-07	62.0	COG3307@1|root,COG3307@2|Bacteria,1PERK@1224|Proteobacteria,2UZJ5@28211|Alphaproteobacteria,4NDP4@97050|Ruegeria	28211|Alphaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH1_k127_7957538_6	290512.Paes_1020	6.693e-67	237.0	COG1194@1|root,COG1194@2|Bacteria,1FD5V@1090|Chlorobi	1090|Chlorobi	L	HhH-GPD family	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YHH1_k127_7999864_1	1128398.Curi_c23480	1.7e-86	290.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,2682Z@186813|unclassified Clostridiales	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
YHH1_k127_7999864_4	335543.Sfum_3405	1.529e-09	66.0	2CEMF@1|root,33GFG@2|Bacteria,1NIQ6@1224|Proteobacteria,42X94@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7999864_3	292459.STH1154	1.332e-19	96.0	COG1011@1|root,COG1011@2|Bacteria,1VK8H@1239|Firmicutes	1239|Firmicutes	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	-
YHH1_k127_7999864_2	526227.Mesil_2652	1.248e-33	139.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	bioH	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
YHH1_k127_7999864_0	330214.NIDE2918	1.861e-106	352.0	COG0154@1|root,COG0154@2|Bacteria,3J0AA@40117|Nitrospirae	40117|Nitrospirae	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH1_k127_80151_0	1121405.dsmv_3003	0.0	1067.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
YHH1_k127_8016837_0	765869.BDW_04975	8.26e-05	54.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18,3.2.1.4	ko:K01179,ko:K01186	ko00500,ko00511,ko00600,ko01100,ko04142,map00500,map00511,map00600,map01100,map04142	-	R04018,R06200,R11307,R11308	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33,GH5,GH9	-	BNR_2,BNR_3,CelD_N,Dockerin_1,Glyco_hydro_9,Laminin_G_3
YHH1_k127_8018796_1	1259795.ARJK01000005_gene1314	2.654e-05	55.0	COG3391@1|root,COG4447@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,1UU3Y@1239|Firmicutes,24C6F@186801|Clostridia	186801|Clostridia	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8018796_0	6669.EFX63769	7.413e-16	90.0	KOG1703@1|root,KOG1703@2759|Eukaryota,38H3P@33154|Opisthokonta,3B96I@33208|Metazoa,3CSTY@33213|Bilateria,41YAP@6656|Arthropoda	33208|Metazoa	TZ	Zinc ion binding	TGFB1I1	GO:0000003,GO:0000187,GO:0000302,GO:0000902,GO:0000904,GO:0001667,GO:0001725,GO:0001763,GO:0001932,GO:0001934,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002102,GO:0002119,GO:0002164,GO:0003006,GO:0003008,GO:0003012,GO:0003674,GO:0003712,GO:0003713,GO:0005102,GO:0005178,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0005875,GO:0005886,GO:0005912,GO:0005924,GO:0005925,GO:0005927,GO:0006139,GO:0006351,GO:0006355,GO:0006366,GO:0006464,GO:0006468,GO:0006508,GO:0006511,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006936,GO:0006950,GO:0006979,GO:0006996,GO:0007010,GO:0007016,GO:0007044,GO:0007045,GO:0007154,GO:0007155,GO:0007160,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007172,GO:0007178,GO:0007179,GO:0007229,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007304,GO:0007306,GO:0007444,GO:0007610,GO:0007631,GO:0008013,GO:0008092,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008285,GO:0008360,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009755,GO:0009790,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010506,GO:0010556,GO:0010557,GO:0010562,GO:0010604,GO:0010628,GO:0010631,GO:0010638,GO:0010646,GO:0010647,GO:0010648,GO:0010717,GO:0010718,GO:0010830,GO:0010927,GO:0014070,GO:0015629,GO:0015630,GO:0016020,GO:0016043,GO:0016070,GO:0016310,GO:0016331,GO:0016363,GO:0016477,GO:0017015,GO:0017166,GO:0018108,GO:0018130,GO:0018193,GO:0018212,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019941,GO:0019953,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030016,GO:0030017,GO:0030027,GO:0030030,GO:0030031,GO:0030032,GO:0030054,GO:0030055,GO:0030154,GO:0030159,GO:0030163,GO:0030511,GO:0030512,GO:0030518,GO:0030521,GO:0030522,GO:0030579,GO:0030703,GO:0030707,GO:0030855,GO:0031252,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031399,GO:0031401,GO:0031430,GO:0031589,GO:0031625,GO:0031672,GO:0031974,GO:0031981,GO:0032147,GO:0032231,GO:0032233,GO:0032268,GO:0032270,GO:0032432,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032774,GO:0032870,GO:0032947,GO:0032956,GO:0032970,GO:0032989,GO:0032991,GO:0033036,GO:0033043,GO:0033554,GO:0033674,GO:0033993,GO:0034329,GO:0034330,GO:0034332,GO:0034333,GO:0034399,GO:0034446,GO:0034599,GO:0034613,GO:0034614,GO:0034622,GO:0034641,GO:0034645,GO:0034654,GO:0035218,GO:0035220,GO:0035239,GO:0035257,GO:0035258,GO:0035295,GO:0035994,GO:0036211,GO:0038191,GO:0040011,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042641,GO:0042755,GO:0042995,GO:0043050,GO:0043085,GO:0043087,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043401,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043434,GO:0043542,GO:0043549,GO:0043632,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044271,GO:0044389,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044703,GO:0044877,GO:0045165,GO:0045185,GO:0045216,GO:0045595,GO:0045596,GO:0045597,GO:0045598,GO:0045599,GO:0045765,GO:0045766,GO:0045859,GO:0045860,GO:0045893,GO:0045935,GO:0045937,GO:0046332,GO:0046483,GO:0046843,GO:0048010,GO:0048041,GO:0048468,GO:0048477,GO:0048495,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048754,GO:0048856,GO:0048869,GO:0048870,GO:0050681,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050839,GO:0050896,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051147,GO:0051153,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051235,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051336,GO:0051338,GO:0051347,GO:0051400,GO:0051427,GO:0051435,GO:0051492,GO:0051493,GO:0051495,GO:0051496,GO:0051603,GO:0051641,GO:0051651,GO:0051674,GO:0051704,GO:0051716,GO:0055120,GO:0060142,GO:0060255,GO:0060396,GO:0060416,GO:0060429,GO:0060562,GO:0061061,GO:0061138,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070161,GO:0070411,GO:0070727,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071375,GO:0071378,GO:0071383,GO:0071396,GO:0071407,GO:0071417,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0080090,GO:0090092,GO:0090100,GO:0090101,GO:0090130,GO:0090132,GO:0090287,GO:0090288,GO:0090304,GO:0097517,GO:0097581,GO:0097659,GO:0099080,GO:0099081,GO:0099512,GO:0110020,GO:0110053,GO:0120025,GO:0120031,GO:0120036,GO:0140110,GO:1901342,GO:1901360,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901739,GO:1902531,GO:1902533,GO:1902680,GO:1902903,GO:1902905,GO:1903506,GO:1903508,GO:1903844,GO:1903845,GO:1903846,GO:1904018,GO:2000026,GO:2000112,GO:2001141	-	ko:K05760	ko04062,ko04370,ko04510,ko04670,ko04810,ko05100,ko05165,ko05203,ko05205,map04062,map04370,map04510,map04670,map04810,map05100,map05165,map05203,map05205	-	-	-	ko00000,ko00001	-	-	-	LIM,Paxillin
YHH1_k127_8018796_2	28583.AMAG_06226T0	0.0005221	45.0	KOG1703@1|root,KOG2710@1|root,KOG1703@2759|Eukaryota,KOG2710@2759|Eukaryota,38H3P@33154|Opisthokonta,3NUWC@4751|Fungi	4751|Fungi	TZ	Gtpase-activating protein	rga1	GO:0000003,GO:0000131,GO:0000278,GO:0000281,GO:0000746,GO:0000747,GO:0000755,GO:0000910,GO:0000917,GO:0003674,GO:0005096,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005933,GO:0005934,GO:0005935,GO:0005937,GO:0006109,GO:0006996,GO:0007010,GO:0007049,GO:0008047,GO:0008150,GO:0008360,GO:0009272,GO:0009889,GO:0009966,GO:0009968,GO:0009987,GO:0010556,GO:0010646,GO:0010648,GO:0010675,GO:0010962,GO:0010981,GO:0016043,GO:0019222,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023057,GO:0030029,GO:0030036,GO:0030234,GO:0030427,GO:0030695,GO:0031323,GO:0031326,GO:0032505,GO:0032506,GO:0032881,GO:0032885,GO:0032950,GO:0032951,GO:0032952,GO:0032953,GO:0032995,GO:0035023,GO:0035024,GO:0042546,GO:0042995,GO:0043085,GO:0043087,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043255,GO:0043332,GO:0043547,GO:0044085,GO:0044087,GO:0044093,GO:0044424,GO:0044444,GO:0044463,GO:0044464,GO:0044703,GO:0044764,GO:0046578,GO:0046580,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051056,GO:0051058,GO:0051128,GO:0051179,GO:0051286,GO:0051301,GO:0051336,GO:0051345,GO:0051641,GO:0051666,GO:0051704,GO:0060237,GO:0060255,GO:0060589,GO:0061640,GO:0065007,GO:0065008,GO:0065009,GO:0071554,GO:0071840,GO:0071852,GO:0080090,GO:0090036,GO:0090038,GO:0090334,GO:0090529,GO:0098772,GO:0120025,GO:0120038,GO:1902410,GO:1902531,GO:1902532,GO:1903047,GO:1903338,GO:2000112	-	-	-	-	-	-	-	-	-	-	LIM,RhoGAP
YHH1_k127_8021537_0	1183438.GKIL_3353	5.186e-102	342.0	COG2008@1|root,COG2008@2|Bacteria,1G4PN@1117|Cyanobacteria	1117|Cyanobacteria	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
YHH1_k127_8021537_2	1499967.BAYZ01000019_gene6321	8.93e-22	97.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	MIase
YHH1_k127_8021537_3	445974.CLORAM_00170	3.135e-15	78.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,3VRNH@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Cold-shock DNA-binding domain protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
YHH1_k127_8021537_1	1379698.RBG1_1C00001G0464	2.364e-40	158.0	COG0170@1|root,COG0170@2|Bacteria,2NQ5M@2323|unclassified Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	sec59	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
YHH1_k127_8026240_0	760568.Desku_2572	1.096e-118	396.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,2646G@186807|Peptococcaceae	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_8026240_2	1347086.CCBA010000005_gene4073	1.06e-29	134.0	COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K02491	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9
YHH1_k127_8026240_3	991905.SL003B_1803	2.048e-19	93.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2U9MH@28211|Alphaproteobacteria,4BS8Z@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
YHH1_k127_8026240_1	1007103.AFHW01000032_gene2246	7.872e-73	250.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
YHH1_k127_8027383_0	1232410.KI421418_gene2401	6.959e-121	394.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,42P7W@68525|delta/epsilon subdivisions,2WMHU@28221|Deltaproteobacteria,43SFF@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF3473)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
YHH1_k127_8027383_2	1210884.HG799469_gene13999	1.099e-92	320.0	COG0438@1|root,COG0438@2|Bacteria,2IZ69@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
YHH1_k127_8027383_1	1121439.dsat_1281	1.285e-109	366.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T55@68525|delta/epsilon subdivisions,2WPW2@28221|Deltaproteobacteria,2MG3X@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_8027383_3	1121439.dsat_1282	6.921e-54	194.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,439Z2@68525|delta/epsilon subdivisions,2X1YW@28221|Deltaproteobacteria,2M834@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_80375_1	502025.Hoch_3258	3.484e-89	300.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,4385Z@68525|delta/epsilon subdivisions,2X3FT@28221|Deltaproteobacteria,2YVWY@29|Myxococcales	28221|Deltaproteobacteria	GK	ROK family	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH1_k127_80375_2	269797.Mbar_A2330	4.256e-64	228.0	COG0500@1|root,arCOG01773@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH1_k127_80375_0	926569.ANT_30000	5.875e-145	474.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
YHH1_k127_8039002_6	660470.Theba_1661	7.084e-11	72.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8039002_5	1123248.KB893381_gene1007	4.343e-17	87.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
YHH1_k127_8039002_1	1379698.RBG1_1C00001G0402	2.06e-189	618.0	COG1200@1|root,COG1200@2|Bacteria,2NNS3@2323|unclassified Bacteria	2|Bacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YHH1_k127_8039002_4	1379698.RBG1_1C00001G0404	1.358e-19	92.0	2EAFJ@1|root,334IY@2|Bacteria,2NRZR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
YHH1_k127_8039002_2	1379698.RBG1_1C00001G0434	5.383e-70	249.0	COG0812@1|root,COG0812@2|Bacteria,2NPHQ@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation	murB	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
YHH1_k127_8039002_0	1379698.RBG1_1C00001G0435	6.088e-271	906.0	COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria	2|Bacteria	M	methyltransferase	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N,SprA_N
YHH1_k127_8039002_3	880073.Calab_0186	6.388e-41	159.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YHH1_k127_8039316_2	237368.SCABRO_03474	4.06e-51	201.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_8039316_4	643648.Slip_1310	1.057e-44	175.0	COG2859@1|root,COG2859@2|Bacteria,1V1Q4@1239|Firmicutes,24GEE@186801|Clostridia	186801|Clostridia	L	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
YHH1_k127_8039316_5	1379698.RBG1_1C00001G0980	3.16e-24	108.0	COG1862@1|root,COG1862@2|Bacteria,2NPY3@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase, YajC	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
YHH1_k127_8039316_3	667014.Thein_0248	2.916e-45	169.0	COG0242@1|root,COG0242@2|Bacteria,2GHK8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
YHH1_k127_8039316_1	1191523.MROS_2423	8.522e-75	262.0	COG0223@1|root,COG0223@2|Bacteria	2|Bacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YHH1_k127_8039316_0	1379698.RBG1_1C00001G0983	1.457e-91	310.0	COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria	2|Bacteria	J	Ribonuclease E/G family	rng	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
YHH1_k127_8084032_0	944481.JAFP01000001_gene1270	7.751e-267	840.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2M6UJ@213113|Desulfurellales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH1_k127_8084032_1	373994.Riv7116_3927	2.727e-72	271.0	COG0517@1|root,COG0784@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG0517@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1G1PE@1117|Cyanobacteria,1HJAX@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
YHH1_k127_8092365_0	797304.Natgr_3586	8.61e-41	166.0	COG0421@1|root,COG0477@1|root,arCOG00050@2157|Archaea,arCOG02682@2157|Archaea,2XUEJ@28890|Euryarchaeota,23T1E@183963|Halobacteria	183963|Halobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YHH1_k127_8092365_2	693661.Arcve_1432	6.324e-10	66.0	arCOG13418@1|root,arCOG13418@2157|Archaea,2Y5VK@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8092365_1	1267533.KB906735_gene4861	1.454e-20	104.0	COG0265@1|root,COG0265@2|Bacteria,3Y7GN@57723|Acidobacteria,2JM8V@204432|Acidobacteriia	204432|Acidobacteriia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8094093_0	98439.AJLL01000010_gene1388	5.063e-258	813.0	COG1770@1|root,COG1770@2|Bacteria,1G1RH@1117|Cyanobacteria,1JHGU@1189|Stigonemataceae	1117|Cyanobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
YHH1_k127_8094093_2	243233.MCA2183	4.895e-78	263.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,1S3N1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YHH1_k127_8094093_3	1207063.P24_16717	9.901e-52	188.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria,2JSQA@204441|Rhodospirillales	204441|Rhodospirillales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
YHH1_k127_8094093_1	1444309.JAQG01000164_gene1837	8.479e-135	454.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,4HPXN@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
YHH1_k127_8099134_0	1123392.AQWL01000007_gene993	4.475e-147	476.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2VJCC@28216|Betaproteobacteria,1KSWE@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YHH1_k127_8112261_2	1379698.RBG1_1C00001G0406	2.344e-26	115.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
YHH1_k127_8112261_3	1121403.AUCV01000010_gene1328	6.93e-13	77.0	COG0655@1|root,COG0655@2|Bacteria,1NANP@1224|Proteobacteria,42Q16@68525|delta/epsilon subdivisions,2WIJ7@28221|Deltaproteobacteria,2MIC1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,LMWPc
YHH1_k127_8112261_0	1423754.BALY01000003_gene1388	8.928e-131	440.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH1_k127_8112261_1	1379698.RBG1_1C00001G0208	3.005e-74	269.0	COG2304@1|root,COG2304@2|Bacteria,2NPT8@2323|unclassified Bacteria	2|Bacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
YHH1_k127_8117709_1	588581.Cpap_3275	5.085e-36	147.0	COG4886@1|root,COG4886@2|Bacteria,1V3DU@1239|Firmicutes,24GSD@186801|Clostridia,3WK0Z@541000|Ruminococcaceae	186801|Clostridia	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_1,CW_binding_2,DUF5011,LRR_4
YHH1_k127_8117709_0	1469948.JPNB01000002_gene3169	4.238e-49	182.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,36EV9@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YHH1_k127_8117825_0	383372.Rcas_0827	1.394e-33	136.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	yueE	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	Guanylate_cyc,HD
YHH1_k127_8117825_1	228410.NE1298	3.244e-14	76.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,1RJUD@1224|Proteobacteria,2WBAA@28216|Betaproteobacteria,372PS@32003|Nitrosomonadales	28216|Betaproteobacteria	PT	TonB-dependent receptor, beta-barrel	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_8,TonB_dep_Rec
YHH1_k127_8120713_19	880073.Calab_1247	1.483e-09	69.0	COG3292@1|root,COG3292@2|Bacteria,2NR3S@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
YHH1_k127_8120713_8	1379698.RBG1_1C00001G0380	5.761e-72	263.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
YHH1_k127_8120713_4	479434.Sthe_1664	1.296e-94	319.0	COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi,27Y1N@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,iPGM_N
YHH1_k127_8120713_7	986075.CathTA2_0732	5.278e-80	271.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,4HBTQ@91061|Bacilli	91061|Bacilli	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
YHH1_k127_8120713_2	240015.ACP_1372	2.151e-122	402.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH1_k127_8120713_9	1379698.RBG1_1C00001G1232	6.257e-70	241.0	COG1403@1|root,COG1403@2|Bacteria,2NPJD@2323|unclassified Bacteria	2|Bacteria	L	HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_4,HNH_5
YHH1_k127_8120713_0	234267.Acid_4539	1.255e-296	927.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,3Y6VT@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
YHH1_k127_8120713_16	32057.KB217478_gene2469	1.18e-30	130.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_3
YHH1_k127_8120713_10	1379698.RBG1_1C00001G0457	1.582e-58	211.0	COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria	2|Bacteria	S	(Rhomboid) family	GlpG	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	Rhomboid
YHH1_k127_8120713_12	880073.Calab_1320	4.38e-51	206.0	COG0739@1|root,COG0739@2|Bacteria,2NR6F@2323|unclassified Bacteria	2|Bacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH1_k127_8120713_13	96561.Dole_0268	1.855e-45	185.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2MHM6@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
YHH1_k127_8120713_20	644548.SCNU_06725	3.414e-08	64.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,4GBPW@85026|Gordoniaceae	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
YHH1_k127_8120713_6	886293.Sinac_6637	3.98e-82	284.0	COG1163@1|root,COG1163@2|Bacteria,2IWYP@203682|Planctomycetes	203682|Planctomycetes	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
YHH1_k127_8120713_5	768704.Desmer_4328	2.48e-88	305.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,261AB@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	spsC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH1_k127_8120713_11	768704.Desmer_4329	2.777e-58	218.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia,26327@186807|Peptococcaceae	186801|Clostridia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
YHH1_k127_8120713_14	945713.IALB_2083	5.609e-34	148.0	COG0728@1|root,COG0728@2|Bacteria	2|Bacteria	M	peptidoglycan biosynthetic process	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YHH1_k127_8120713_1	1379698.RBG1_1C00001G1539	1.92e-131	429.0	COG0399@1|root,COG0399@2|Bacteria,2NNS2@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH1_k127_8120713_3	857293.CAAU_2200	2.409e-99	329.0	COG1044@1|root,COG1044@2|Bacteria,1UHYP@1239|Firmicutes,25E78@186801|Clostridia,36F2P@31979|Clostridiaceae	186801|Clostridia	M	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2
YHH1_k127_8120713_15	891968.Anamo_1218	1.051e-30	136.0	COG3206@1|root,COG3206@2|Bacteria,3TAZ7@508458|Synergistetes	508458|Synergistetes	M	PFAM lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
YHH1_k127_8120713_17	1150600.ADIARSV_2853	1.282e-13	81.0	COG1596@1|root,COG1596@2|Bacteria,4NEXJ@976|Bacteroidetes,1IPNG@117747|Sphingobacteriia	976|Bacteroidetes	M	export protein	kpsD	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
YHH1_k127_8144868_0	1379698.RBG1_1C00001G0326	1.868e-145	473.0	COG1966@1|root,COG1966@2|Bacteria,2NNP2@2323|unclassified Bacteria	2|Bacteria	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
YHH1_k127_8144868_1	1379698.RBG1_1C00001G0325	4.407e-87	307.0	COG2199@1|root,COG3706@2|Bacteria,2NPJ3@2323|unclassified Bacteria	2|Bacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,GGDEF,MASE3,PAS_3,PAS_4,Response_reg
YHH1_k127_8144868_2	1379698.RBG1_1C00001G0324	3.527e-12	70.0	COG1472@1|root,COG1472@2|Bacteria,2NNZB@2323|unclassified Bacteria	2|Bacteria	G	Glycoside hydrolase family 3 domain protein	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
YHH1_k127_8147403_1	518766.Rmar_2323	7.979e-39	149.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1FIMG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
YHH1_k127_8147403_2	1379698.RBG1_1C00001G1769	1.457e-25	111.0	COG0640@1|root,COG0640@2|Bacteria,2NQ1G@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
YHH1_k127_8147403_0	913325.N799_06400	1.071e-109	374.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1X37F@135614|Xanthomonadales	135614|Xanthomonadales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
YHH1_k127_8147403_3	485913.Krac_9231	5.147e-11	65.0	COG0504@1|root,COG0504@2|Bacteria	2|Bacteria	F	CTP synthase activity	-	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YHH1_k127_8171256_3	1232410.KI421413_gene750	5.708e-11	76.0	COG2885@1|root,COG3210@1|root,COG5184@1|root,COG5276@1|root,COG2885@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
YHH1_k127_8171256_0	1379698.RBG1_1C00001G0518	1.167e-135	461.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
YHH1_k127_8171256_2	290315.Clim_1597	1.079e-13	79.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YHH1_k127_8171256_1	1209989.TepiRe1_0608	8.835e-23	100.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,42EWF@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH1_k127_8187033_0	1123392.AQWL01000004_gene2796	9.663e-225	712.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VMHQ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidase S8	-	-	3.4.21.66	ko:K08651,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
YHH1_k127_818731_7	1504672.669785143	9.442e-09	61.0	2DS2J@1|root,33E85@2|Bacteria,1NESD@1224|Proteobacteria,2VWJX@28216|Betaproteobacteria,4AFDA@80864|Comamonadaceae	28216|Betaproteobacteria	N	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
YHH1_k127_818731_2	1005048.CFU_0304	7.581e-68	233.0	COG1873@1|root,COG1873@2|Bacteria,1QTWZ@1224|Proteobacteria,2VT3J@28216|Betaproteobacteria,474JG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
YHH1_k127_818731_0	525897.Dbac_1180	0.0	1184.0	COG0693@1|root,COG0753@1|root,COG0693@2|Bacteria,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,42MIN@68525|delta/epsilon subdivisions,2WJC5@28221|Deltaproteobacteria,2M91H@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the catalase family	katE	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel,DJ-1_PfpI
YHH1_k127_818731_6	525897.Dbac_1179	5.222e-13	69.0	2EMKC@1|root,33F8T@2|Bacteria,1NP5C@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_818731_1	525897.Dbac_1162	8.458e-151	480.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,42PW8@68525|delta/epsilon subdivisions,2WKCT@28221|Deltaproteobacteria,2M9X0@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM Alpha beta hydrolase	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4
YHH1_k127_818731_4	697282.Mettu_0012	2.961e-44	165.0	COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,1SBIG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YHH1_k127_818731_3	1123393.KB891316_gene1574	3.336e-52	187.0	28RKB@1|root,2ZDZ5@2|Bacteria,1PAWP@1224|Proteobacteria,2WC7G@28216|Betaproteobacteria,1KT73@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_818731_5	159087.Daro_2074	2.115e-34	134.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
YHH1_k127_820446_6	316067.Geob_2847	1.971e-14	76.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
YHH1_k127_820446_2	926550.CLDAP_26360	1.132e-66	248.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_820446_5	1379698.RBG1_1C00001G0237	5.213e-19	101.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,LVIVD
YHH1_k127_820446_3	1415779.JOMH01000001_gene627	5.086e-33	131.0	COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,1S8Z1@1236|Gammaproteobacteria,1X8PD@135614|Xanthomonadales	135614|Xanthomonadales	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH1_k127_820446_1	2325.TKV_c04890	4.951e-102	338.0	COG0863@1|root,COG0863@2|Bacteria,1TPR7@1239|Firmicutes,24A3P@186801|Clostridia,42ESE@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
YHH1_k127_820446_4	639030.JHVA01000001_gene3918	9.138e-23	106.0	COG1943@1|root,COG1943@2|Bacteria,3Y4PK@57723|Acidobacteria,2JJBM@204432|Acidobacteriia	204432|Acidobacteriia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH1_k127_820446_0	1379698.RBG1_1C00001G0278	4.058e-159	507.0	COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH1_k127_8245352_3	1499967.BAYZ01000103_gene3745	8.813e-65	239.0	COG0013@1|root,COG0013@2|Bacteria,2NPQB@2323|unclassified Bacteria	2|Bacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaS_2	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YHH1_k127_8245352_1	1379698.RBG1_1C00001G0864	4.595e-151	520.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744,ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA,OstA_C
YHH1_k127_8245352_6	1379698.RBG1_1C00001G0865	4.885e-27	113.0	COG0776@1|root,COG0776@2|Bacteria,2NPTH@2323|unclassified Bacteria	2|Bacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530,ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH1_k127_8245352_0	1379698.RBG1_1C00001G0866	1.078e-210	679.0	COG1674@1|root,COG1674@2|Bacteria,2NNVB@2323|unclassified Bacteria	2|Bacteria	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YHH1_k127_8245352_2	857293.CAAU_1723	2.105e-107	362.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,36E1K@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
YHH1_k127_8245352_4	1379698.RBG1_1C00001G0868	4.742e-56	203.0	COG0741@1|root,COG0741@2|Bacteria,2NPKN@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase SLT domain	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
YHH1_k127_8245352_5	1379698.RBG1_1C00001G0869	2.56e-28	122.0	COG4105@1|root,COG4105@2|Bacteria,2NPZ3@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	yfiO	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
YHH1_k127_8316731_0	909663.KI867151_gene2966	8.641e-188	615.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1NT36@1224|Proteobacteria,42ZEC@68525|delta/epsilon subdivisions,2WU3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
YHH1_k127_8323908_6	1379698.RBG1_1C00001G1343	8.904e-59	207.0	COG2199@1|root,COG2199@2|Bacteria,2NS3Z@2323|unclassified Bacteria	2|Bacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
YHH1_k127_8323908_2	1379698.RBG1_1C00001G1339	3.336e-192	620.0	COG1297@1|root,COG1297@2|Bacteria,2NP0C@2323|unclassified Bacteria	2|Bacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
YHH1_k127_8323908_9	1379698.RBG1_1C00001G0373	3.501e-36	148.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane
YHH1_k127_8323908_7	861299.J421_3477	1.52e-55	203.0	COG0767@1|root,COG0767@2|Bacteria,1ZUC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YHH1_k127_8323908_5	290512.Paes_1695	2.759e-61	221.0	COG1127@1|root,COG1127@2|Bacteria,1FDRZ@1090|Chlorobi	1090|Chlorobi	Q	PFAM ABC transporter related	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YHH1_k127_8323908_8	1123376.AUIU01000011_gene1054	1.144e-38	156.0	COG1463@1|root,COG1463@2|Bacteria,3J164@40117|Nitrospirae	40117|Nitrospirae	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
YHH1_k127_8323908_1	1191523.MROS_2740	1.071e-195	627.0	COG3185@1|root,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
YHH1_k127_8323908_0	1382306.JNIM01000001_gene2570	2.979e-241	756.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YHH1_k127_8323908_4	929713.NIASO_10095	6.543e-75	260.0	COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,1IRW8@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YHH1_k127_8323908_3	96561.Dole_2179	3.315e-169	545.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2MHYZ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Carbamoyl-phosphate synthase L chain	pccA	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YHH1_k127_8323908_10	1123256.KB907927_gene1613	3.624e-14	79.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1X2ZC@135614|Xanthomonadales	135614|Xanthomonadales	I	carboxylase	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
YHH1_k127_8344845_10	1379698.RBG1_1C00001G0668	1.964e-21	100.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	DUF1566,Phenol_MetA_deg
YHH1_k127_8344845_8	1379698.RBG1_1C00001G0581	9.389e-31	141.0	COG2911@1|root,COG2911@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cohesin,FlgD_ig,Peptidase_S74
YHH1_k127_8344845_4	1123242.JH636435_gene2260	1.125e-51	188.0	COG0454@1|root,COG0456@2|Bacteria,2J4PU@203682|Planctomycetes	203682|Planctomycetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH1_k127_8344845_13	999411.HMPREF1092_00451	9.228e-05	53.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia,36J2Z@31979|Clostridiaceae	186801|Clostridia	M	transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
YHH1_k127_8344845_3	459349.CLOAM0275	8.427e-56	218.0	COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria	2|Bacteria	C	lyase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
YHH1_k127_8344845_5	686340.Metal_2156	9.445e-51	184.0	arCOG06832@1|root,31H39@2|Bacteria,1RJBH@1224|Proteobacteria,1SNXE@1236|Gammaproteobacteria,1XGIS@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8344845_6	1123267.JONN01000001_gene1239	4.515e-35	147.0	2C1YS@1|root,2ZD2Y@2|Bacteria	2|Bacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
YHH1_k127_8344845_0	1123267.JONN01000001_gene1238	1.511e-232	753.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MRJP
YHH1_k127_8344845_7	383372.Rcas_2068	9.678e-32	130.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,375JF@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_8344845_12	634498.mru_0513	7.408e-08	57.0	COG1366@1|root,arCOG06891@2157|Archaea,2Y5F7@28890|Euryarchaeota,23PVU@183925|Methanobacteria	183925|Methanobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
YHH1_k127_8344845_11	639283.Snov_1996	1.92e-15	82.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,2UCGB@28211|Alphaproteobacteria,3F07N@335928|Xanthobacteraceae	28211|Alphaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
YHH1_k127_8344845_2	1191523.MROS_0148	1.73e-136	445.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
YHH1_k127_8344845_1	945713.IALB_0266	2.141e-220	692.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrome_C554
YHH1_k127_8344845_9	1532558.JL39_10075	3.683e-22	104.0	COG2169@1|root,COG2169@2|Bacteria,1R5KX@1224|Proteobacteria,2U44Z@28211|Alphaproteobacteria,4B8NK@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
YHH1_k127_8347983_3	552811.Dehly_0160	8.217e-39	147.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH1_k127_8347983_4	1117647.M5M_10210	5.042e-11	70.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,1S3ZJ@1236|Gammaproteobacteria,1J79B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH1_k127_8347983_0	1128421.JAGA01000001_gene2171	3.081e-133	431.0	COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YHH1_k127_8347983_2	1379698.RBG1_1C00001G1455	1.663e-45	170.0	COG0698@1|root,COG0698@2|Bacteria,2NPF4@2323|unclassified Bacteria	2|Bacteria	G	ribose 5-phosphate isomerase B	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
YHH1_k127_8347983_1	1379698.RBG1_1C00001G1453	2.697e-65	226.0	COG0112@1|root,COG0112@2|Bacteria,2NP28@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_3081,iIT341.HP0183	SHMT
YHH1_k127_835266_0	1089552.KI911559_gene3676	2.173e-32	136.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,2TT7I@28211|Alphaproteobacteria,2JRHJ@204441|Rhodospirillales	204441|Rhodospirillales	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH1_k127_835266_1	765910.MARPU_10695	1.108e-14	85.0	COG3307@1|root,COG3307@2|Bacteria,1QYUF@1224|Proteobacteria,1T3V4@1236|Gammaproteobacteria,1X2TM@135613|Chromatiales	135613|Chromatiales	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8371551_0	909663.KI867150_gene397	1.643e-174	553.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MREN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
YHH1_k127_8371551_1	1232683.ADIMK_1132	1.554e-46	175.0	COG0431@1|root,COG0431@2|Bacteria,1MXQ8@1224|Proteobacteria,1S8XI@1236|Gammaproteobacteria,46DMJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
YHH1_k127_8379384_1	497321.C664_18984	1.354e-51	184.0	COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,2VSJA@28216|Betaproteobacteria,2KZB1@206389|Rhodocyclales	206389|Rhodocyclales	L	COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
YHH1_k127_8379384_0	395019.Bmul_5725	1.727e-171	541.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHER@28216|Betaproteobacteria,1K13F@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
YHH1_k127_8379384_2	1122603.ATVI01000005_gene3196	3.155e-21	96.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1X78T@135614|Xanthomonadales	135614|Xanthomonadales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
YHH1_k127_8395424_1	1047013.AQSP01000106_gene1757	1.8e-56	199.0	COG4690@1|root,COG4690@2|Bacteria,2NQBZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
YHH1_k127_8395424_2	395961.Cyan7425_4608	4.734e-32	144.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1G3C4@1117|Cyanobacteria,3KKPN@43988|Cyanothece	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
YHH1_k127_8395424_0	452637.Oter_3300	2.268e-58	226.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
YHH1_k127_8398641_15	269797.Mbar_A0157	5.112e-25	106.0	COG0004@1|root,arCOG04397@2157|Archaea,2XTEB@28890|Euryarchaeota,2N971@224756|Methanomicrobia	224756|Methanomicrobia	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
YHH1_k127_8398641_6	1191523.MROS_2401	4.798e-50	186.0	29A93@1|root,32UVK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
YHH1_k127_8398641_13	1313304.CALK_0675	1.09e-25	121.0	COG1639@1|root,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
YHH1_k127_8398641_14	1379698.RBG1_1C00001G1224	1.156e-25	125.0	COG0745@1|root,COG0745@2|Bacteria	1379698.RBG1_1C00001G1224|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8398641_1	1304880.JAGB01000001_gene243	1.12e-116	392.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YHH1_k127_8398641_2	945713.IALB_2321	3.888e-106	372.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	pepN1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
YHH1_k127_8398641_8	1380390.JIAT01000014_gene6288	1.888e-43	182.0	COG0028@1|root,COG0515@1|root,COG1470@1|root,COG2133@1|root,COG3291@1|root,COG0028@2|Bacteria,COG0515@2|Bacteria,COG1470@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,PA14,PKD
YHH1_k127_8398641_0	1379698.RBG1_1C00001G0885	6.593e-190	621.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338,ko:K08675	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03029	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH1_k127_8398641_3	1379698.RBG1_1C00001G1417	3.066e-99	356.0	COG1204@1|root,COG1204@2|Bacteria,2NS5J@2323|unclassified Bacteria	2|Bacteria	L	helicase superfamily c-terminal domain	-	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,Helicase_C,Peptidase_C14
YHH1_k127_8398641_7	984262.SGRA_3562	6.747e-45	184.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1IYS6@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
YHH1_k127_8398641_18	319225.Plut_1585	2.822e-09	67.0	COG0810@1|root,COG0810@2|Bacteria,1FE18@1090|Chlorobi	1090|Chlorobi	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH1_k127_8398641_5	1379698.RBG1_1C00001G1358	8.149e-52	192.0	COG0810@1|root,COG0810@2|Bacteria,2NQ1D@2323|unclassified Bacteria	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
YHH1_k127_8398641_11	1379698.RBG1_1C00001G1357	2.646e-33	137.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH1_k127_8398641_10	1379698.RBG1_1C00001G1356	3.325e-36	142.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
YHH1_k127_8398641_4	1379698.RBG1_1C00001G1355	1.826e-77	267.0	COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH1_k127_8398641_19	1382358.JHVN01000001_gene1022	1.625e-08	68.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,21VAU@150247|Anoxybacillus	91061|Bacilli	S	Sel1-like repeats.	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
YHH1_k127_8398641_16	768671.ThimaDRAFT_3239	1.028e-18	100.0	COG2244@1|root,COG2244@2|Bacteria,1PF64@1224|Proteobacteria,1TKCZ@1236|Gammaproteobacteria,1X1Y8@135613|Chromatiales	135613|Chromatiales	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8398641_17	1157490.EL26_10565	2.113e-16	90.0	COG2162@1|root,COG2162@2|Bacteria,1VA4Y@1239|Firmicutes,4I95N@91061|Bacilli,27A04@186823|Alicyclobacillaceae	91061|Bacilli	Q	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_2
YHH1_k127_8398641_12	1158338.JNLJ01000005_gene1339	2.426e-30	131.0	2E7Q4@1|root,3325M@2|Bacteria,2G503@200783|Aquificae	200783|Aquificae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2,Cytochrome_C554
YHH1_k127_8398641_9	234267.Acid_4926	1.792e-42	158.0	COG1063@1|root,COG1063@2|Bacteria,3Y7C2@57723|Acidobacteria	57723|Acidobacteria	E	Alcohol dehydrogenase GroES-associated	-	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
YHH1_k127_8445567_7	1380346.JNIH01000040_gene2646	4.819e-25	111.0	COG1215@1|root,COG1215@2|Bacteria,2I3M7@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_8445567_3	1123252.ATZF01000008_gene30	3.086e-39	168.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	B_lectin,Bac_surface_Ag,C5-epim_C,Cu_amine_oxidN1,MerB,POTRA,SBP_bac_5,SLH
YHH1_k127_8445567_0	1379698.RBG1_1C00001G0598	6.826e-141	451.0	COG0568@1|root,COG0568@2|Bacteria,2NNY9@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH1_k127_8445567_1	671143.DAMO_3115	5.238e-94	326.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
YHH1_k127_8445567_2	1340493.JNIF01000003_gene1407	4.805e-58	209.0	COG0235@1|root,COG0235@2|Bacteria,3Y4E0@57723|Acidobacteria	57723|Acidobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
YHH1_k127_8445567_4	644966.Tmar_0910	7.401e-35	148.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,2491B@186801|Clostridia	186801|Clostridia	E	PFAM aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_8445567_5	1379698.RBG1_1C00001G0302	1.641e-28	119.0	COG1539@1|root,COG1539@2|Bacteria,2NQ1A@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
YHH1_k127_8445567_6	1123300.AUIN01000009_gene303	3.384e-26	116.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli	91061|Bacilli	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
YHH1_k127_8448648_0	1123234.AUKI01000016_gene3028	8.626e-53	208.0	COG1196@1|root,COG1196@2|Bacteria,4NR6T@976|Bacteroidetes,1I9GW@117743|Flavobacteriia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8450728_4	926554.KI912639_gene1730	0.0001065	48.0	COG0719@1|root,COG0719@2|Bacteria,1WJ1E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	TIGRFAM FeS assembly protein SufD	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
YHH1_k127_8450728_0	1379698.RBG1_1C00001G0736	3.132e-226	708.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
YHH1_k127_8450728_1	1379698.RBG1_1C00001G0735	3.415e-98	326.0	COG0396@1|root,COG0396@2|Bacteria,2NNYE@2323|unclassified Bacteria	2|Bacteria	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
YHH1_k127_8450728_3	1267535.KB906767_gene4689	1.107e-30	127.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH1_k127_8450728_2	338963.Pcar_2070	2.043e-41	161.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,42RE2@68525|delta/epsilon subdivisions,2WNEN@28221|Deltaproteobacteria,43THX@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
YHH1_k127_8451107_0	338963.Pcar_0118	4.714e-108	361.0	COG3568@1|root,COG3568@2|Bacteria,1RA4I@1224|Proteobacteria	1224|Proteobacteria	L	deoxyribonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding,Exo_endo_phos,HHH_3,LTD
YHH1_k127_8451107_1	438753.AZC_0875	3.17e-11	65.0	2EGQC@1|root,33AGI@2|Bacteria,1NGA3@1224|Proteobacteria,2UKAV@28211|Alphaproteobacteria,3F20N@335928|Xanthobacteraceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PsiF_repeat
YHH1_k127_8461971_2	398767.Glov_2384	1.837e-13	73.0	2ATWF@1|root,31JFP@2|Bacteria,1RK55@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8461971_1	398767.Glov_2384	3.012e-40	156.0	2ATWF@1|root,31JFP@2|Bacteria,1RK55@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8461971_0	580332.Slit_1331	2.474e-103	339.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,44VI7@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
YHH1_k127_8470763_0	1379698.RBG1_1C00001G0614	6.194e-190	610.0	COG1505@1|root,COG1505@2|Bacteria,2NNUB@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
YHH1_k127_8505883_7	391612.CY0110_21667	2.527e-25	111.0	COG0016@1|root,COG0016@2|Bacteria,1G05R@1117|Cyanobacteria,3KGM9@43988|Cyanothece	1117|Cyanobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YHH1_k127_8505883_5	1379698.RBG1_1C00001G1118	8.732e-35	136.0	COG0292@1|root,COG0292@2|Bacteria,2NPQQ@2323|unclassified Bacteria	2|Bacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
YHH1_k127_8505883_8	1286171.EAL2_c08850	1.878e-16	80.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,25X8W@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
YHH1_k127_8505883_3	1379698.RBG1_1C00001G1116	3.902e-58	208.0	COG0290@1|root,COG0290@2|Bacteria,2NPDH@2323|unclassified Bacteria	2|Bacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
YHH1_k127_8505883_0	1269813.ATUL01000025_gene2750	3.271e-238	754.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1WVYK@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
YHH1_k127_8505883_2	360104.CCC13826_0537	1.912e-121	403.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2YMBX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH1_k127_8505883_1	1304888.ATWF01000002_gene396	4.128e-177	577.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
YHH1_k127_8505883_4	290402.Cbei_4710	1.942e-42	177.0	COG1052@1|root,COG1052@2|Bacteria,1VV1J@1239|Firmicutes,249XK@186801|Clostridia,36HAW@31979|Clostridiaceae	186801|Clostridia	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8505883_6	240016.ABIZ01000001_gene110	2.586e-33	148.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia,2ITQF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
YHH1_k127_8517786_4	459349.CLOAM0969	0.0001857	44.0	COG0388@1|root,COG0388@2|Bacteria,2NPKU@2323|unclassified Bacteria	2|Bacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
YHH1_k127_8517786_2	526222.Desal_3269	1.013e-28	121.0	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,42VQ4@68525|delta/epsilon subdivisions,2WS47@28221|Deltaproteobacteria,2MGUU@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM Methylated-DNA- protein -cysteine	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
YHH1_k127_8517786_0	398767.Glov_1187	3.139e-67	240.0	28K48@1|root,2Z9T8@2|Bacteria,1R4TF@1224|Proteobacteria,42MAD@68525|delta/epsilon subdivisions,2WKEM@28221|Deltaproteobacteria,43V42@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
YHH1_k127_8517786_1	1345697.M493_06860	2.907e-40	160.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,4HDIE@91061|Bacilli,1WF9J@129337|Geobacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_8522305_1	670307.HYPDE_23308	6.909e-32	126.0	COG0778@1|root,COG0778@2|Bacteria,1RDJ6@1224|Proteobacteria,2U44Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YHH1_k127_8522305_0	994573.T472_0205120	2.765e-57	222.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1VIJZ@1239|Firmicutes	1239|Firmicutes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH1_k127_8522305_2	1121899.Q764_05500	7.414e-28	130.0	COG2304@1|root,COG3291@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia,2P0KQ@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3
YHH1_k127_8524267_1	459349.CLOAM1019	1.837e-57	216.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	3.6.3.44	ko:K06147,ko:K06148,ko:K11085,ko:K16787,ko:K18104,ko:K18889	ko01501,ko02010,map01501,map02010	M00582,M00700,M00707	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	3.A.1,3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.117,3.A.1.123,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
YHH1_k127_8524267_2	269799.Gmet_3416	4.198e-33	130.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42N2U@68525|delta/epsilon subdivisions,2WJRR@28221|Deltaproteobacteria,43TU4@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH1_k127_8524267_0	935948.KE386495_gene1996	4.407e-87	307.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42F65@68295|Thermoanaerobacterales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
YHH1_k127_8524267_3	357804.Ping_3330	1.392e-07	62.0	COG2984@1|root,COG2984@2|Bacteria,1PHTD@1224|Proteobacteria,1SKT1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
YHH1_k127_8536879_1	981369.JQMJ01000003_gene7480	6.452e-52	198.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH1_k127_8536879_0	552811.Dehly_1535	1.057e-81	282.0	COG3547@1|root,COG3547@2|Bacteria,2G8GZ@200795|Chloroflexi	200795|Chloroflexi	L	transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH1_k127_853903_1	1379698.RBG1_1C00001G0958	3.212e-61	221.0	COG1561@1|root,COG1561@2|Bacteria,2NPG5@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	DUF1732,YicC_N
YHH1_k127_853903_2	445335.CBN_2490	1.547e-46	175.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,36EVE@31979|Clostridiaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
YHH1_k127_853903_0	1379698.RBG1_1C00001G0961	1.78e-150	488.0	COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
YHH1_k127_8594345_5	266779.Meso_0343	6.419e-14	75.0	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,43ISW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH1_k127_8594345_2	93220.LV28_09965	2.913e-111	368.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VMN7@28216|Betaproteobacteria,1K3PN@119060|Burkholderiaceae	28216|Betaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase	gyaR	-	1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R00717,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH1_k127_8594345_0	1095769.CAHF01000018_gene821	2.616e-267	837.0	COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,2VJ2Q@28216|Betaproteobacteria,47290@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
YHH1_k127_8594345_3	1095769.CAHF01000018_gene821	1.404e-99	328.0	COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,2VJ2Q@28216|Betaproteobacteria,47290@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
YHH1_k127_8594345_1	1095769.CAHF01000018_gene822	6.065e-190	600.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2VHEX@28216|Betaproteobacteria,472KJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
YHH1_k127_8594345_4	1379281.AVAG01000020_gene1062	2.322e-80	273.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M915@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
YHH1_k127_8601177_0	1499968.TCA2_2767	1.754e-26	129.0	COG1361@1|root,COG2931@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH1_k127_8601177_1	1111479.AXAR01000001_gene376	3.44e-05	48.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli	91061|Bacilli	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YHH1_k127_8622352_2	272558.10174312	2.941e-45	182.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZCMB@1386|Bacillus	91061|Bacilli	E	Aminotransferase	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_8622352_1	690850.Desaf_1817	6.358e-49	181.0	COG2050@1|root,COG2050@2|Bacteria,1NA8E@1224|Proteobacteria,42XJH@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
YHH1_k127_8622352_3	765911.Thivi_0864	1.799e-06	55.0	COG1433@1|root,COG1433@2|Bacteria,1MZTM@1224|Proteobacteria,1S93S@1236|Gammaproteobacteria,1WYME@135613|Chromatiales	135613|Chromatiales	S	PFAM Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
YHH1_k127_8622352_0	517418.Ctha_1801	1.165e-98	330.0	COG2126@1|root,COG2126@2|Bacteria,1FDC0@1090|Chlorobi	1090|Chlorobi	J	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
YHH1_k127_8641435_1	1121033.AUCF01000015_gene1496	2.222e-49	184.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2U1PX@28211|Alphaproteobacteria,2JRDE@204441|Rhodospirillales	204441|Rhodospirillales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
YHH1_k127_8641435_5	1454004.AW11_02135	3.976e-06	53.0	COG3386@1|root,COG3386@2|Bacteria,1RA3Q@1224|Proteobacteria,2VZHV@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8641435_0	1395571.TMS3_0122920	1.077e-287	898.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RYKY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH1_k127_8641435_2	314278.NB231_09623	7.564e-23	99.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1T3U5@1236|Gammaproteobacteria,1X1MF@135613|Chromatiales	135613|Chromatiales	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
YHH1_k127_8641435_3	317936.Nos7107_5300	3.587e-16	82.0	COG0477@1|root,COG2814@2|Bacteria,1G2N2@1117|Cyanobacteria,1HIQV@1161|Nostocales	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
YHH1_k127_8646621_0	1125863.JAFN01000001_gene2600	6.051e-102	347.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria	1224|Proteobacteria	C	PFAM FAD linked oxidase domain protein	dld	GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.1.1.303,1.1.1.4,1.1.2.4,1.1.3.15	ko:K00004,ko:K00102,ko:K00104	ko00620,ko00630,ko00650,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map00650,map01100,map01110,map01120,map01130	-	R00197,R00475,R02855,R02946,R10504	RC00042,RC00044,RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YHH1_k127_8646621_2	550540.Fbal_1356	6.02e-37	152.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RZUI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
YHH1_k127_8646621_1	1123228.AUIH01000013_gene211	3.441e-49	189.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
YHH1_k127_8666975_3	518766.Rmar_0285	0.0002232	53.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1FIRB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48,FlgD_ig
YHH1_k127_8666975_0	324602.Caur_2797	6.081e-149	489.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,2G64U@200795|Chloroflexi,374ZG@32061|Chloroflexia	32061|Chloroflexia	P	YidE YbjL duplication domain protein	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
YHH1_k127_8666975_1	243365.CV_1343	1.904e-77	267.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria,2KQAQ@206351|Neisseriales	206351|Neisseriales	S	Psort location CytoplasmicMembrane, score 10.00	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
YHH1_k127_8666975_2	316055.RPE_1141	2.256e-52	199.0	COG3039@1|root,COG3328@1|root,COG3039@2|Bacteria,COG3328@2|Bacteria,1MWD6@1224|Proteobacteria,2VART@28211|Alphaproteobacteria,3K01W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
YHH1_k127_8672799_4	459349.CLOAM0891	3.518e-28	132.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y
YHH1_k127_8672799_5	1191523.MROS_2238	9.828e-23	115.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	CBM_6,fn3
YHH1_k127_8672799_0	1379698.RBG1_1C00001G0386	7.42e-55	203.0	COG1216@1|root,COG1216@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
YHH1_k127_8672799_1	1379698.RBG1_1C00001G0384	1.043e-42	172.0	COG0438@1|root,COG0438@2|Bacteria,2NPP9@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_8672799_2	1379698.RBG1_1C00001G0383	1.977e-40	162.0	COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	remC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_8672799_6	795797.C497_15887	7.782e-14	82.0	arCOG03319@1|root,arCOG03319@2157|Archaea,2XT0V@28890|Euryarchaeota,23TEK@183963|Halobacteria	183963|Halobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
YHH1_k127_8672799_3	1379698.RBG1_1C00001G0381	1.145e-31	140.0	COG3292@1|root,COG3292@2|Bacteria,2NR3S@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
YHH1_k127_8675096_0	880073.Calab_1599	2.717e-159	526.0	COG2864@1|root,COG2864@2|Bacteria,2NNNM@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b subunit of formate dehydrogenase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
YHH1_k127_8675096_1	96561.Dole_1704	6.085e-33	138.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_868200_0	1460640.JCM19046_1440	4.571e-44	167.0	COG3153@1|root,COG3153@2|Bacteria,1UHU2@1239|Firmicutes,4HXQQ@91061|Bacilli,1ZS42@1386|Bacillus	91061|Bacilli	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH1_k127_868200_1	1242864.D187_002479	3.363e-30	128.0	COG3386@1|root,COG3386@2|Bacteria,1NFEJ@1224|Proteobacteria,43BX0@68525|delta/epsilon subdivisions,2X77S@28221|Deltaproteobacteria,2YVY8@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_868200_3	1894.JOER01000015_gene7963	1.121e-10	70.0	2D579@1|root,32TID@2|Bacteria,2IMWE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8686951_3	78898.MVEG_12259T0	5.75e-14	84.0	COG0571@1|root,KOG0701@2759|Eukaryota,39MBT@33154|Opisthokonta,3P0EB@4751|Fungi,1GSK2@112252|Fungi incertae sedis	4751|Fungi	A	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH1_k127_8686951_4	1289135.A966_06575	3.538e-06	56.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
YHH1_k127_8686951_2	522772.Dacet_2645	1.465e-15	78.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
YHH1_k127_8686951_1	228410.NE0155	2.631e-17	85.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VQF1@28216|Betaproteobacteria,37275@32003|Nitrosomonadales	28216|Betaproteobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
YHH1_k127_8686951_0	522772.Dacet_0668	3.837e-101	332.0	COG2801@1|root,COG2801@2|Bacteria,2GG32@200930|Deferribacteres	200930|Deferribacteres	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
YHH1_k127_8688847_1	439235.Dalk_1819	5.588e-62	220.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42PH3@68525|delta/epsilon subdivisions,2WJZH@28221|Deltaproteobacteria,2MIN0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
YHH1_k127_8688847_0	1379698.RBG1_1C00001G0775	1.073e-130	427.0	COG0484@1|root,COG0484@2|Bacteria,2NQUM@2323|unclassified Bacteria	2|Bacteria	O	Class III cytochrome C family	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2
YHH1_k127_8688847_3	1379698.RBG1_1C00001G1208	1.683e-10	65.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	mshB	-	-	ko:K02456,ko:K02650,ko:K10924,ko:K10925	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,Pilin,T2SSG
YHH1_k127_8688847_2	657309.BXY_23420	4.259e-27	122.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,2FPA4@200643|Bacteroidia,4AKI6@815|Bacteroidaceae	976|Bacteroidetes	M	COG COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8698076_4	743722.Sph21_1299	1.015e-10	74.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1IQZP@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
YHH1_k127_8698076_3	1379698.RBG1_1C00001G1338	7.518e-54	210.0	COG0457@1|root,COG0457@2|Bacteria,2NPEN@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
YHH1_k127_8698076_1	1052684.PPM_3162	1.453e-135	443.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,26QDD@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
YHH1_k127_8698076_0	1379698.RBG1_1C00001G1562	6.84e-216	691.0	COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
YHH1_k127_8698076_2	743722.Sph21_0527	2.071e-105	351.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1IQI3@117747|Sphingobacteriia	976|Bacteroidetes	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
YHH1_k127_8716930_0	398767.Glov_2733	7.869e-63	225.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42QX1@68525|delta/epsilon subdivisions,2WMNH@28221|Deltaproteobacteria,43TQD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
YHH1_k127_8716930_1	1379698.RBG1_1C00001G0237	1.412e-25	122.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,LVIVD
YHH1_k127_8717221_11	76114.ebA1594	2.152e-07	61.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VS0R@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
YHH1_k127_8717221_9	290317.Cpha266_0035	9.41e-12	74.0	COG0760@1|root,COG0760@2|Bacteria,1FDC8@1090|Chlorobi	1090|Chlorobi	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N,SurA_N_3
YHH1_k127_8717221_7	927658.AJUM01000022_gene1000	1.85e-26	117.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,2FNS9@200643|Bacteroidia	976|Bacteroidetes	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
YHH1_k127_8717221_8	553218.CAMRE0001_2179	2.922e-13	72.0	COG1188@1|root,COG1188@2|Bacteria,1Q5X3@1224|Proteobacteria,42VKA@68525|delta/epsilon subdivisions,2YPZ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
YHH1_k127_8717221_0	1379698.RBG1_1C00001G1661	5.734e-181	578.0	COG1239@1|root,COG1239@2|Bacteria,2NQQG@2323|unclassified Bacteria	2|Bacteria	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0958	Mg_chelatase,Sigma54_activat
YHH1_k127_8717221_1	1379698.RBG1_1C00001G1660	2.317e-136	445.0	COG4867@1|root,COG4867@2|Bacteria,2NQZ8@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
YHH1_k127_8717221_3	237368.SCABRO_02302	4.66e-64	231.0	COG2206@1|root,COG2206@2|Bacteria,2J3D3@203682|Planctomycetes	203682|Planctomycetes	T	signal transduction HD GYP protein	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
YHH1_k127_8717221_10	864702.OsccyDRAFT_4898	2.337e-08	61.0	COG2259@1|root,COG2259@2|Bacteria,1G78G@1117|Cyanobacteria,1HCP0@1150|Oscillatoriales	1117|Cyanobacteria	S	Membrane	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
YHH1_k127_8717221_5	1123234.AUKI01000008_gene998	1.405e-33	142.0	29FE7@1|root,302BX@2|Bacteria,4NMTG@976|Bacteroidetes,1I1WT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8717221_4	316067.Geob_2146	1.118e-41	158.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2WQ6E@28221|Deltaproteobacteria,43V3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
YHH1_k127_8717221_6	1408424.JHYI01000015_gene4733	2.064e-28	117.0	COG0838@1|root,COG0838@2|Bacteria,1V6P3@1239|Firmicutes,4HIFX@91061|Bacilli,1ZGE2@1386|Bacillus	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YHH1_k127_8746417_3	1519464.HY22_07435	1.464e-07	61.0	COG3386@1|root,COG3386@2|Bacteria,1FF2C@1090|Chlorobi	1090|Chlorobi	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8746417_0	1116375.VEJY3_23976	1.48e-85	305.0	COG4412@1|root,COG4412@2|Bacteria,1P5IH@1224|Proteobacteria,1RPYC@1236|Gammaproteobacteria,1XTRH@135623|Vibrionales	135623|Vibrionales	M	Immune inhibitor A peptidase M6	prtV	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PKD,Peptidase_M6
YHH1_k127_8746417_1	880073.Calab_0314	3.208e-20	106.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,F5_F8_type_C,RicinB_lectin_2,Ricin_B_lectin,fn3
YHH1_k127_8746417_2	1507.HMPREF0262_01691	2.734e-10	64.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,36MNT@31979|Clostridiaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
YHH1_k127_875226_0	1268068.PG5_44800	2.976e-205	648.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
YHH1_k127_875226_1	1178825.ALIH01000030_gene2257	6.159e-12	71.0	2E3AK@1|root,2ZC4K@2|Bacteria,4NMMM@976|Bacteroidetes,1I1F6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8755454_4	1232428.CAVO010000022_gene882	2.493e-07	54.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8755454_3	582899.Hden_3088	2.133e-13	76.0	2EI58@1|root,33BWK@2|Bacteria,1NMVP@1224|Proteobacteria,2UKIB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8755454_2	1379698.RBG1_1C00001G1198	2.438e-22	97.0	COG1145@1|root,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	fdxN	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	Fer4,HTH_3,HTH_31
YHH1_k127_8755454_6	1191523.MROS_2413	2.14e-05	55.0	2CG1Y@1|root,2Z9QX@2|Bacteria	2|Bacteria	S	COG NOG19146 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YHH1_k127_8755454_1	1379698.RBG1_1C00001G1698	8.937e-99	332.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
YHH1_k127_8755454_0	266117.Rxyl_0312	9.928e-128	431.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4CQV5@84995|Rubrobacteria	84995|Rubrobacteria	EU	Peptidase S9, prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YHH1_k127_876016_0	744872.Spica_0331	3.068e-278	880.0	COG0058@1|root,COG0058@2|Bacteria,2J5KC@203691|Spirochaetes	203691|Spirochaetes	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
YHH1_k127_876016_3	1444309.JAQG01000164_gene1837	1.083e-124	425.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,4HPXN@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
YHH1_k127_876016_2	309807.SRU_1244	6.763e-138	455.0	COG0612@1|root,COG0612@2|Bacteria,4PICD@976|Bacteroidetes,1FJRH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_876016_1	1089550.ATTH01000001_gene1066	1.67e-144	484.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1FJZ6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_8773341_1	1128421.JAGA01000004_gene2684	4.512e-50	179.0	COG2148@1|root,COG2148@2|Bacteria,2NPJQ@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	epsL	-	-	ko:K19428	-	-	-	-	ko00000,ko01000	-	-	-	Bac_transf
YHH1_k127_8773341_2	205922.Pfl01_3547	1.46e-20	93.0	2DEEZ@1|root,2ZMQX@2|Bacteria,1P4SX@1224|Proteobacteria,1SVV2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8773341_0	926569.ANT_23610	2.214e-96	321.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YHH1_k127_8776054_10	1265845.PWEIH_01807	2.254e-13	75.0	2E5AU@1|root,3302Y@2|Bacteria,1VB5Y@1239|Firmicutes,4HPUD@91061|Bacilli,26KPZ@186820|Listeriaceae	91061|Bacilli	S	Src homology 3 domains	-	-	-	-	-	-	-	-	-	-	-	-	SH3_1,SH3_2
YHH1_k127_8776054_9	1500301.JQMF01000024_gene1964	1.492e-15	86.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2UPS7@28211|Alphaproteobacteria,4BICH@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
YHH1_k127_8776054_3	1304885.AUEY01000038_gene2578	1.501e-32	130.0	COG1832@1|root,COG1832@2|Bacteria,1PUW7@1224|Proteobacteria,42T5D@68525|delta/epsilon subdivisions,2WPHZ@28221|Deltaproteobacteria,2MK69@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
YHH1_k127_8776054_7	742159.HMPREF0004_5593	2.115e-22	103.0	COG0454@1|root,COG0456@2|Bacteria,1QU9D@1224|Proteobacteria,2VUVY@28216|Betaproteobacteria,3T7UY@506|Alcaligenaceae	28216|Betaproteobacteria	K	GNAT family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
YHH1_k127_8776054_2	224324.aq_346	2.713e-39	155.0	COG0193@1|root,COG0193@2|Bacteria,2G42F@200783|Aquificae	200783|Aquificae	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
YHH1_k127_8776054_8	1379698.RBG1_1C00001G0133	5.874e-16	85.0	COG0360@1|root,COG0360@2|Bacteria,2NQ1Q@2323|unclassified Bacteria	2|Bacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
YHH1_k127_8776054_6	1379698.RBG1_1C00001G0132	1.469e-25	107.0	COG0629@1|root,COG0629@2|Bacteria,2NPP5@2323|unclassified Bacteria	2|Bacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YHH1_k127_8776054_5	1379698.RBG1_1C00001G0131	7.769e-28	114.0	COG0238@1|root,COG0238@2|Bacteria,2NPTU@2323|unclassified Bacteria	2|Bacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
YHH1_k127_8776054_11	879212.DespoDRAFT_01790	1.566e-05	56.0	COG4241@1|root,COG4241@2|Bacteria,1N4XJ@1224|Proteobacteria,42QCS@68525|delta/epsilon subdivisions,2WKDT@28221|Deltaproteobacteria,2MIFQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
YHH1_k127_8776054_1	1379698.RBG1_1C00001G0130	2.16e-44	166.0	COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria	2|Bacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
YHH1_k127_8776054_0	1379698.RBG1_1C00001G0129	5.097e-57	203.0	COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria	2|Bacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03617,ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
YHH1_k127_8776054_4	644966.Tmar_2362	2.349e-32	144.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia	186801|Clostridia	E	PFAM Extracellular ligand-binding receptor	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YHH1_k127_8798212_2	595460.RRSWK_07231	1.149e-39	151.0	COG4914@1|root,COG4914@2|Bacteria,2J4D4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8798212_0	96561.Dole_2064	4.682e-147	473.0	COG1148@1|root,COG1148@2|Bacteria,1N26U@1224|Proteobacteria,43BRJ@68525|delta/epsilon subdivisions,2X72E@28221|Deltaproteobacteria,2MPJ6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
YHH1_k127_8798212_1	555779.Dthio_PD2938	3.761e-73	261.0	COG1373@1|root,COG1373@2|Bacteria,1R7UA@1224|Proteobacteria,42QMY@68525|delta/epsilon subdivisions,2WK60@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
YHH1_k127_8798212_4	926569.ANT_21570	8.316e-09	59.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH1_k127_880432_4	926560.KE387025_gene4045	2.154e-24	116.0	COG1520@1|root,COG1520@2|Bacteria,1WMGH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
YHH1_k127_880432_0	1379698.RBG1_1C00001G1445	5.05e-265	846.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
YHH1_k127_880432_1	273068.TTE1955	1.386e-101	341.0	COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,248K9@186801|Clostridia,42F1Z@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
YHH1_k127_880432_3	671143.DAMO_1641	8.584e-53	205.0	COG0241@1|root,COG0859@1|root,COG0241@2|Bacteria,COG0859@2|Bacteria,2NPK4@2323|unclassified Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	rfaF	-	2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28	ko:K02841,ko:K02843,ko:K02849,ko:K03271,ko:K03272,ko:K03273	ko00540,ko01100,map00540,map01100	M00064,M00080	R05644,R05645,R05646,R05647,R09768,R09769,R09771	RC00002,RC00017,RC00078,RC00434	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Hydrolase_like
YHH1_k127_880432_2	1123070.KB899250_gene465	1.43e-57	209.0	COG1968@1|root,COG1968@2|Bacteria,46SP6@74201|Verrucomicrobia,2IURU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Bacitracin resistance protein BacA	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
YHH1_k127_8816434_0	1047013.AQSP01000051_gene2576	1.383e-50	202.0	COG2220@1|root,COG2220@2|Bacteria,2NRBH@2323|unclassified Bacteria	2|Bacteria	S	Beta-lactamase superfamily domain	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
YHH1_k127_8816434_1	7668.SPU_009060-tr	7.426e-17	95.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	ko:K15503,ko:K17593	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_4,Ank_5,Pkinase,SAM_1,ZU5
YHH1_k127_8819297_1	1379698.RBG1_1C00001G1274	6.477e-23	100.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	atoC	-	-	ko:K07712,ko:K07713,ko:K07714,ko:K10943	ko02020,ko05111,map02020,map05111	M00497,M00499,M00500,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_8819297_0	1379698.RBG1_1C00001G1558	4.757e-60	213.0	COG1974@1|root,COG1974@2|Bacteria,2NPJG@2323|unclassified Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
YHH1_k127_8824329_1	1379698.RBG1_1C00001G0582	0.000928	50.0	COG2911@1|root,COG2911@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cohesin,FlgD_ig,Peptidase_S74
YHH1_k127_8824329_0	1353529.M899_2244	5.249e-135	437.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,42MK7@68525|delta/epsilon subdivisions,2WJCJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM ketose-bisphosphate aldolase, class-II	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
YHH1_k127_8838297_1	1379698.RBG1_1C00001G1654	5.914e-52	188.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH1_k127_8838297_0	1379698.RBG1_1C00001G1265	2.246e-195	624.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_8838297_2	740709.A10D4_10154	1.907e-19	97.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,2QFQV@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YHH1_k127_8845489_6	1408310.JHUW01000010_gene2474	7.463e-14	81.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,2FNY6@200643|Bacteroidia	976|Bacteroidetes	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
YHH1_k127_8845489_0	1519464.HY22_10360	2.807e-214	678.0	COG0154@1|root,COG0154@2|Bacteria,1FDMC@1090|Chlorobi	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH1_k127_8845489_8	1384054.N790_06850	0.0002412	49.0	2BXY5@1|root,33DGA@2|Bacteria,1NP8G@1224|Proteobacteria,1SJ5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Regulator of ribonuclease activity B	-	-	-	-	-	-	-	-	-	-	-	-	RraB
YHH1_k127_8845489_2	1379698.RBG1_1C00001G1870	9.283e-117	388.0	COG0232@1|root,COG0232@2|Bacteria,2NP3S@2323|unclassified Bacteria	2|Bacteria	F	Phosphohydrolase-associated domain	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
YHH1_k127_8845489_4	926549.KI421517_gene2095	6.574e-17	94.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,47KV2@768503|Cytophagia	976|Bacteroidetes	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
YHH1_k127_8845489_3	1379698.RBG1_1C00001G1866	7.812e-103	353.0	COG2204@1|root,COG2204@2|Bacteria,2NQDH@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	fhlA	-	-	ko:K03413,ko:K13589	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506,M00512	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_8845489_1	555079.Toce_1819	2.331e-166	548.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,42FKG@68295|Thermoanaerobacterales	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
YHH1_k127_8845489_7	929556.Solca_1759	2.82e-13	76.0	2EM7W@1|root,33EX0@2|Bacteria,4P5SH@976|Bacteroidetes,1J02V@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8847727_3	153721.MYP_809	1.144e-106	354.0	arCOG06766@1|root,2Z87F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8847727_9	324602.Caur_1424	1.069e-80	279.0	COG0524@1|root,COG0524@2|Bacteria,2GAA6@200795|Chloroflexi,376QU@32061|Chloroflexia	32061|Chloroflexia	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH1_k127_8847727_12	765420.OSCT_1020	7.104e-50	185.0	COG0558@1|root,COG0558@2|Bacteria,2GAQW@200795|Chloroflexi,3773G@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YHH1_k127_8847727_4	1303518.CCALI_01954	2.21e-104	348.0	COG0536@1|root,COG0536@2|Bacteria	2|Bacteria	C	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
YHH1_k127_8847727_8	1379698.RBG1_1C00001G1623	8.154e-82	285.0	COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria	2|Bacteria	LU	DNA recombination-mediator protein A	dprA	-	5.99.1.2	ko:K03168,ko:K04096	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_processg_A
YHH1_k127_8847727_14	1236959.BAMT01000006_gene337	4.469e-25	108.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,2KN6U@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM phosphoryl transfer system HPr	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
YHH1_k127_8847727_2	273068.TTE2334	2.278e-113	386.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
YHH1_k127_8847727_5	1209989.TepiRe1_0750	8.898e-94	319.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,42EVQ@68295|Thermoanaerobacterales	186801|Clostridia	G	TIGRFAM bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
YHH1_k127_8847727_15	717231.Flexsi_2294	2.69e-12	69.0	2ENTB@1|root,33GEH@2|Bacteria,2GG66@200930|Deferribacteres	200930|Deferribacteres	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8847727_7	1379698.RBG1_1C00001G0115	1.655e-83	287.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8847727_13	1379698.RBG1_1C00001G0114	5.987e-41	159.0	29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8847727_10	1379698.RBG1_1C00001G0113	1.667e-56	208.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8847727_11	1379698.RBG1_1C00001G0112	1.417e-54	200.0	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8847727_6	1519464.HY22_02585	2.764e-88	302.0	COG1209@1|root,COG1209@2|Bacteria,1FD8Z@1090|Chlorobi	1090|Chlorobi	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
YHH1_k127_8847727_1	1379698.RBG1_1C00001G1854	2.471e-180	571.0	COG0192@1|root,COG0192@2|Bacteria,2NNYF@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YHH1_k127_8847727_0	1379698.RBG1_1C00001G1855	4.315e-184	584.0	COG0499@1|root,COG0499@2|Bacteria,2NNQE@2323|unclassified Bacteria	2|Bacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
YHH1_k127_8847727_16	216591.BCAL1017	0.0007318	42.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2VP05@28216|Betaproteobacteria,1K8AN@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH1_k127_8855169_2	690850.Desaf_2134	8.094e-75	266.0	COG5653@1|root,COG5653@2|Bacteria,1Q8ZI@1224|Proteobacteria,431YG@68525|delta/epsilon subdivisions,2WWCM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
YHH1_k127_8855169_8	1235815.BAIX01000002_gene207	2.606e-16	86.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
YHH1_k127_8855169_3	1444711.CCJF01000005_gene1766	1.099e-54	199.0	COG0164@1|root,COG0164@2|Bacteria,2JFYJ@204428|Chlamydiae	204428|Chlamydiae	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH1_k127_8855169_6	1125863.JAFN01000001_gene3518	4.501e-26	115.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
YHH1_k127_8855169_4	1392502.JNIO01000008_gene2344	8.79e-40	151.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4H4PC@909932|Negativicutes	909932|Negativicutes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
YHH1_k127_8855169_1	1379698.RBG1_1C00001G0950	3.882e-77	266.0	COG0336@1|root,COG0336@2|Bacteria,2NP5G@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA_m1G_MT
YHH1_k127_8855169_5	1321786.HMPREF1992_00053	4.204e-27	117.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4H56U@909932|Negativicutes	909932|Negativicutes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
YHH1_k127_8855169_7	1504823.CCMM01000008_gene880	1.88e-25	110.0	COG0228@1|root,COG0228@2|Bacteria,2NPWN@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
YHH1_k127_8855169_0	880073.Calab_2050	6.933e-159	512.0	COG0541@1|root,COG0541@2|Bacteria,2NNT9@2323|unclassified Bacteria	2|Bacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
YHH1_k127_8855169_9	1158294.JOMI01000007_gene703	1.676e-14	76.0	COG1073@1|root,COG1073@2|Bacteria,4NQNM@976|Bacteroidetes	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
YHH1_k127_8943375_4	156889.Mmc1_3630	6.382e-148	476.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TRAH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
YHH1_k127_8943375_3	1379698.RBG1_1C00001G1056	1.926e-170	565.0	COG3383@1|root,COG3383@2|Bacteria,2NNQ6@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	hcnA	-	1.17.1.9,1.4.99.5,1.5.3.1	ko:K00123,ko:K00302,ko:K10814	ko00260,ko00460,ko00630,ko00680,ko01100,ko01110,ko01120,ko01200,map00260,map00460,map00630,map00680,map01100,map01110,map01120,map01200	-	R00374,R00519,R00610,R05704	RC00060,RC00557,RC02796,RC02808	ko00000,ko00001,ko01000,ko02042	-	-	-	Fer2_4
YHH1_k127_8943375_5	1379698.RBG1_1C00001G1057	4.025e-127	415.0	COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH1_k127_8943375_7	1379698.RBG1_1C00001G1875	4.788e-71	243.0	COG1143@1|root,COG1143@2|Bacteria,2NPQR@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00337,ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
YHH1_k127_8943375_8	1379698.RBG1_1C00001G1058	1.141e-30	130.0	COG0839@1|root,COG0839@2|Bacteria,2NPUC@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YHH1_k127_8943375_9	237368.SCABRO_02000	1.248e-30	123.0	COG0713@1|root,COG0713@2|Bacteria,2J0GU@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YHH1_k127_8943375_0	1379698.RBG1_1C00001G1060	2.885e-234	741.0	COG1009@1|root,COG1009@2|Bacteria,2NNU6@2323|unclassified Bacteria	2|Bacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
YHH1_k127_8943375_1	1379698.RBG1_1C00001G1061	2.776e-216	682.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
YHH1_k127_8943375_11	370438.PTH_1606	8.306e-15	76.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
YHH1_k127_8943375_6	398767.Glov_3125	2.594e-123	411.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YHH1_k127_8943375_2	1379698.RBG1_1C00001G1211	4.172e-193	613.0	COG0034@1|root,COG0034@2|Bacteria,2NNSY@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iSB619.SA_RS05225	GATase_6,GATase_7,Pribosyltran
YHH1_k127_895910_0	247490.KSU1_C0714	3.637e-144	500.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
YHH1_k127_895910_3	448385.sce0969	0.0006882	51.0	COG1409@1|root,COG1409@2|Bacteria,1R0BM@1224|Proteobacteria,43CTY@68525|delta/epsilon subdivisions,2X81I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_895995_19	644282.Deba_0427	1.207e-17	86.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_895995_7	880073.Calab_0027	1.981e-101	351.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YHH1_k127_895995_9	1379698.RBG1_1C00001G0346	9.291e-93	314.0	COG0341@1|root,COG0341@2|Bacteria,2NP4P@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YHH1_k127_895995_14	1519464.HY22_12185	1.307e-57	227.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
YHH1_k127_895995_17	880073.Calab_0298	5.205e-40	155.0	COG2322@1|root,COG2322@2|Bacteria	2|Bacteria	S	membrane	yozB	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420
YHH1_k127_895995_15	880073.Calab_0299	5.208e-57	218.0	COG1999@1|root,COG1999@2|Bacteria,2NQ63@2323|unclassified Bacteria	2|Bacteria	O	SCO1/SenC	ypmQ	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
YHH1_k127_895995_13	880073.Calab_0300	1.064e-62	235.0	COG1612@1|root,COG1612@2|Bacteria,2NQ3D@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
YHH1_k127_895995_18	880073.Calab_0301	7.125e-28	117.0	2ASAK@1|root,31HPU@2|Bacteria,2NQ6K@2323|unclassified Bacteria	2|Bacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
YHH1_k127_895995_10	880073.Calab_0302	1.401e-91	305.0	COG1845@1|root,COG1845@2|Bacteria,2NPIG@2323|unclassified Bacteria	2|Bacteria	C	cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
YHH1_k127_895995_2	880073.Calab_0303	2.815e-254	793.0	COG0843@1|root,COG0843@2|Bacteria,2NNTQ@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
YHH1_k127_895995_5	880073.Calab_0304	8.943e-126	409.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2NNSH@2323|unclassified Bacteria	2|Bacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275,ko:K17223	ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120	M00155,M00595	R00081,R10151	RC00016,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
YHH1_k127_895995_11	518766.Rmar_0228	1.771e-76	267.0	COG1999@1|root,COG1999@2|Bacteria,4NU1J@976|Bacteroidetes,1FJ7I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
YHH1_k127_895995_4	1519464.HY22_05025	1.266e-131	432.0	COG4531@1|root,COG4531@2|Bacteria	2|Bacteria	P	zinc ion transport	actF	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_895995_12	880073.Calab_0308	3.614e-67	235.0	COG2010@1|root,COG2010@2|Bacteria,2NPQJ@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YHH1_k127_895995_16	1089550.ATTH01000001_gene1173	4.114e-48	178.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1FJ8P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Protein of unknown function (DUF3341)	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YHH1_k127_895995_3	880073.Calab_0310	2.982e-221	694.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	actC	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
YHH1_k127_895995_1	880073.Calab_0311	0.0	1092.0	COG0437@1|root,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hybA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
YHH1_k127_895995_6	1519464.HY22_13440	2.08e-104	342.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,GSu_C4xC__C2xCH,UVR
YHH1_k127_895995_8	1519464.HY22_13445	1.475e-96	324.0	COG0109@1|root,COG0109@2|Bacteria	2|Bacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
YHH1_k127_895995_0	330214.NIDE1937	0.0	1561.0	COG0209@1|root,COG0209@2|Bacteria,3J0MG@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
YHH1_k127_895995_20	481448.Minf_0977	2.961e-14	74.0	COG1472@1|root,COG1472@2|Bacteria,46WV5@74201|Verrucomicrobia,37GQ5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
YHH1_k127_9075766_0	1379698.RBG1_1C00001G1789	2.282e-238	783.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
YHH1_k127_9075766_1	1379698.RBG1_1C00001G1788	6.769e-14	73.0	COG2067@1|root,COG3292@1|root,COG2067@2|Bacteria,COG3292@2|Bacteria,2NPQZ@2323|unclassified Bacteria	2|Bacteria	I	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Reg_prop,Reprolysin_5,VCBS
YHH1_k127_9085234_13	1379698.RBG1_1C00001G1567	2.748e-38	150.0	COG0203@1|root,COG0203@2|Bacteria,2NPYQ@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein L17	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02879,ko:K16193	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
YHH1_k127_9085234_1	1379698.RBG1_1C00001G1568	1.155e-126	413.0	COG0202@1|root,COG0202@2|Bacteria,2NNQQ@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YHH1_k127_9085234_3	1379698.RBG1_1C00001G1569	1.998e-83	281.0	COG0522@1|root,COG0522@2|Bacteria,2NPCC@2323|unclassified Bacteria	2|Bacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
YHH1_k127_9085234_11	1379698.RBG1_1C00001G1570	1.069e-49	179.0	COG0100@1|root,COG0100@2|Bacteria,2NPCN@2323|unclassified Bacteria	2|Bacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YHH1_k127_9085234_9	1379698.RBG1_1C00001G1571	1.223e-52	188.0	COG0099@1|root,COG0099@2|Bacteria,2NPKH@2323|unclassified Bacteria	2|Bacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YHH1_k127_9085234_22	660470.Theba_0701	6.338e-12	65.0	COG0257@1|root,COG0257@2|Bacteria,2GDKI@200918|Thermotogae	200918|Thermotogae	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
YHH1_k127_9085234_14	1379698.RBG1_1C00001G1573	6.764e-38	143.0	COG0361@1|root,COG0361@2|Bacteria,2NPNU@2323|unclassified Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
YHH1_k127_9085234_2	1120985.AUMI01000006_gene2203	4.046e-90	304.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H2VZ@909932|Negativicutes	909932|Negativicutes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH1_k127_9085234_6	867903.ThesuDRAFT_00579	3.421e-64	227.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3WCG7@538999|Clostridiales incertae sedis	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
YHH1_k127_9085234_0	1379698.RBG1_1C00001G1576	1.921e-186	591.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YHH1_k127_9085234_12	1122985.HMPREF1991_00645	1.146e-41	157.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,2FSJF@200643|Bacteroidia	976|Bacteroidetes	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
YHH1_k127_9085234_20	945713.IALB_0930	3.204e-20	91.0	COG1841@1|root,COG1841@2|Bacteria	2|Bacteria	J	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
YHH1_k127_9085234_10	1379698.RBG1_1C00001G1579	2.68e-52	188.0	COG0098@1|root,COG0098@2|Bacteria,2NPGN@2323|unclassified Bacteria	2|Bacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
YHH1_k127_9085234_17	1158318.ATXC01000001_gene1258	2.02e-28	118.0	COG0256@1|root,COG0256@2|Bacteria,2G476@200783|Aquificae	200783|Aquificae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
YHH1_k127_9085234_7	1121104.AQXH01000010_gene2432	1.54e-62	220.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1IRC9@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
YHH1_k127_9085234_15	439235.Dalk_1901	2.686e-34	135.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,2MJZV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
YHH1_k127_9085234_19	59374.Fisuc_1409	2.205e-24	104.0	COG0199@1|root,COG0199@2|Bacteria	2|Bacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
YHH1_k127_9085234_4	264732.Moth_2448	5.02e-79	268.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,42F2S@68295|Thermoanaerobacterales	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
YHH1_k127_9085234_18	945713.IALB_0923	2.164e-28	117.0	COG0198@1|root,COG0198@2|Bacteria	2|Bacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
YHH1_k127_9085234_8	1379698.RBG1_1C00001G1586	5.126e-54	191.0	COG0093@1|root,COG0093@2|Bacteria,2NPCS@2323|unclassified Bacteria	2|Bacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
YHH1_k127_9085234_16	518766.Rmar_0851	9.749e-31	123.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1FJGB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
YHH1_k127_9085234_21	1379698.RBG1_1C00001G1588	2.083e-15	79.0	COG0255@1|root,COG0255@2|Bacteria,2NQ49@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal L29 protein	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
YHH1_k127_9085234_5	880073.Calab_2133	3.943e-66	227.0	COG0197@1|root,COG0197@2|Bacteria,2NPC6@2323|unclassified Bacteria	2|Bacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
YHH1_k127_9114256_6	1121918.ARWE01000001_gene2193	2.398e-17	86.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,42RMP@68525|delta/epsilon subdivisions,2X5PZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
YHH1_k127_9114256_7	204669.Acid345_4293	9.002e-14	79.0	COG2823@1|root,COG2823@2|Bacteria,3Y99E@57723|Acidobacteria,2JP08@204432|Acidobacteriia	204432|Acidobacteriia	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9114256_5	525245.HMPREF0044_0854	1.121e-17	91.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4D431@85005|Actinomycetales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_9114256_9	1121923.GPUN_0304	2.804e-08	64.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,465S4@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_9114256_10	558884.JRGM01000042_gene1341	3.134e-08	60.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQZD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
YHH1_k127_9114256_4	153948.NAL212_2787	7.92e-21	96.0	2AHT0@1|root,3185H@2|Bacteria,1PZUW@1224|Proteobacteria,2WC28@28216|Betaproteobacteria,373KC@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9114256_3	338969.Rfer_3310	1.126e-24	109.0	2B4TG@1|root,31XK1@2|Bacteria,1RIY8@1224|Proteobacteria,2VTMB@28216|Betaproteobacteria,4AF7U@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9114256_2	1379270.AUXF01000001_gene2611	9.505e-38	149.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,GerE,PocR,Response_reg
YHH1_k127_9114256_1	1379270.AUXF01000001_gene2611	1.747e-49	185.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,GerE,PocR,Response_reg
YHH1_k127_9114256_0	1158165.KB898872_gene1125	6.363e-171	544.0	COG1537@1|root,COG1537@2|Bacteria,1R36N@1224|Proteobacteria	1224|Proteobacteria	S	nuclear-transcribed mRNA catabolic process, no-go decay	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9114256_8	1265505.ATUG01000001_gene4602	1.896e-11	75.0	COG2984@1|root,COG2984@2|Bacteria,1PHTD@1224|Proteobacteria,42NW3@68525|delta/epsilon subdivisions,2WKHH@28221|Deltaproteobacteria,2MI3A@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
YHH1_k127_9131487_0	452637.Oter_1454	4.576e-118	388.0	COG0841@1|root,COG0841@2|Bacteria,46SER@74201|Verrucomicrobia	74201|Verrucomicrobia	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH1_k127_9131487_2	452637.Oter_1455	1.373e-47	186.0	COG0845@1|root,COG0845@2|Bacteria,46US2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YHH1_k127_9131487_4	439235.Dalk_0193	1.92e-14	75.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,42VWR@68525|delta/epsilon subdivisions,2WS4U@28221|Deltaproteobacteria,2MKU4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
YHH1_k127_9131487_1	1009370.ALO_18817	1.722e-87	299.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4H28B@909932|Negativicutes	909932|Negativicutes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
YHH1_k127_9131487_3	1249480.B649_09540	6.081e-31	129.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C,Cytochrom_D1,DHOR,Lactonase,RicinB_lectin_2
YHH1_k127_9166839_2	765420.OSCT_1327	9.711e-22	100.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi	200795|Chloroflexi	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YHH1_k127_9166839_0	552811.Dehly_0931	3.74e-210	678.0	COG0474@1|root,COG0474@2|Bacteria	2|Bacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
YHH1_k127_9166839_1	443144.GM21_2050	3.079e-37	151.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions,2WJGS@28221|Deltaproteobacteria,43T2T@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH1_k127_916991_8	631454.N177_2727	4.301e-27	128.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2U1Z6@28211|Alphaproteobacteria,1JQMZ@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
YHH1_k127_916991_7	1121403.AUCV01000008_gene1542	1.679e-58	226.0	COG4870@1|root,COG4870@2|Bacteria,1RJ0M@1224|Proteobacteria,42V4Z@68525|delta/epsilon subdivisions,2WRZX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
YHH1_k127_916991_2	1379698.RBG1_1C00001G1819	1.233e-116	407.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_916991_1	945713.IALB_0421	7.467e-147	471.0	COG1294@1|root,COG1294@2|Bacteria	2|Bacteria	C	oxidative phosphorylation	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,ic_1306.c1120	Cyt_bd_oxida_II
YHH1_k127_916991_0	945713.IALB_0420	1.909e-190	603.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
YHH1_k127_916991_5	1121428.DESHY_110105___1	1.044e-81	280.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,260MZ@186807|Peptococcaceae	186801|Clostridia	E	PFAM ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
YHH1_k127_916991_6	1232410.KI421420_gene3141	1.083e-59	213.0	COG0569@1|root,COG0569@2|Bacteria,1R7KM@1224|Proteobacteria,42PJH@68525|delta/epsilon subdivisions,2WMZT@28221|Deltaproteobacteria,43SGD@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
YHH1_k127_916991_3	1121918.ARWE01000001_gene2902	1.52e-92	320.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,42MBI@68525|delta/epsilon subdivisions,2WIZ9@28221|Deltaproteobacteria,43S5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
YHH1_k127_916991_4	28072.Nos7524_5522	1.989e-83	282.0	COG4221@1|root,COG4221@2|Bacteria,1G182@1117|Cyanobacteria,1HICK@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
YHH1_k127_9175863_3	518766.Rmar_1750	0.0004873	46.0	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4P230@976|Bacteroidetes	2|Bacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec
YHH1_k127_9175863_0	1123024.AUII01000008_gene1885	4.558e-110	365.0	COG0451@1|root,COG0451@2|Bacteria,2GNYX@201174|Actinobacteria,4E1KX@85010|Pseudonocardiales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YHH1_k127_9175863_2	663278.Ethha_0976	1.415e-29	123.0	COG4231@1|root,COG4231@2|Bacteria,1VAJQ@1239|Firmicutes,24MVB@186801|Clostridia	186801|Clostridia	C	PFAM 4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
YHH1_k127_9175863_1	1121918.ARWE01000001_gene1466	3.286e-30	124.0	COG1456@1|root,COG1456@2|Bacteria,1R6BH@1224|Proteobacteria,42NKF@68525|delta/epsilon subdivisions,2WJ72@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel	-	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
YHH1_k127_9216325_8	1379698.RBG1_1C00001G0126	1.595e-25	112.0	2C451@1|root,2ZRAU@2|Bacteria,2NS2X@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9216325_9	1379698.RBG1_1C00001G0125	1.007e-23	108.0	2EGJW@1|root,3110Q@2|Bacteria,2NS2A@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9216325_12	658187.LDG_8098	9.33e-09	66.0	COG0457@1|root,COG4976@1|root,COG0457@2|Bacteria,COG4976@2|Bacteria,1RAIT@1224|Proteobacteria,1S6MW@1236|Gammaproteobacteria,1JCMX@118969|Legionellales	118969|Legionellales	S	Tetratricopeptide repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23,TPR_1,TPR_16,TPR_2,TPR_7,TPR_8
YHH1_k127_9216325_6	1379698.RBG1_1C00001G0664	3.463e-32	137.0	COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria	2|Bacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
YHH1_k127_9216325_3	309807.SRU_1184	2.442e-41	160.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1FJ9B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function (DUF1949)	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
YHH1_k127_9216325_2	237368.SCABRO_00251	9.144e-49	186.0	COG0524@1|root,COG0524@2|Bacteria,2IX8I@203682|Planctomycetes	203682|Planctomycetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH1_k127_9216325_7	880073.Calab_2990	5.58e-32	131.0	COG0671@1|root,COG0671@2|Bacteria,2NPZ6@2323|unclassified Bacteria	2|Bacteria	I	Phosphoesterase, PA-phosphatase related	-	-	3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	-	R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
YHH1_k127_9216325_4	891968.Anamo_1817	7.931e-41	158.0	COG2110@1|root,COG2110@2|Bacteria,3TB5Z@508458|Synergistetes	508458|Synergistetes	S	C-terminal domain of histone	-	-	-	-	-	-	-	-	-	-	-	-	Macro
YHH1_k127_9216325_1	1379698.RBG1_1C00001G0533	3.798e-116	385.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH1_k127_9216325_0	1379698.RBG1_1C00001G0532	7.049e-165	529.0	COG0156@1|root,COG0156@2|Bacteria,2NNMX@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_9216325_13	1336237.JAEE01000001_gene1884	3.161e-07	62.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	dksA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
YHH1_k127_9216325_5	1379698.RBG1_1C00001G0520	7.994e-40	161.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	CHASE2,GAF,GAF_2,HATPase_c_2,SpoIIE
YHH1_k127_9221098_3	573370.DMR_36460	9.226e-24	118.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2M8CQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
YHH1_k127_9221098_1	679926.Mpet_0033	1.07e-44	186.0	COG0642@1|root,arCOG06712@1|root,arCOG06193@2157|Archaea,arCOG06712@2157|Archaea	679926.Mpet_0033|-	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9221098_4	1232437.KL662028_gene2796	2.277e-11	78.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,TPR_12,Y_Y_Y
YHH1_k127_9221098_0	1210884.HG799462_gene8899	2.384e-101	349.0	COG2382@1|root,COG2382@2|Bacteria,2J2KX@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YHH1_k127_9221098_2	682795.AciX8_4231	3.229e-24	111.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,DUF4145,Pentapeptide,RDD
YHH1_k127_9221098_5	1034807.FBFL15_2870	0.000105	52.0	2BET9@1|root,328IV@2|Bacteria,4NRHR@976|Bacteroidetes,1IAG8@117743|Flavobacteriia	976|Bacteroidetes	S	SMI1 / KNR4 family	-	-	-	-	-	-	-	-	-	-	-	-	SMI1_KNR4
YHH1_k127_926404_0	1038859.AXAU01000003_gene6016	0.0	1123.0	COG0439@1|root,COG4770@1|root,COG4799@1|root,COG0439@2|Bacteria,COG4770@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,2TWYZ@28211|Alphaproteobacteria,3JUPC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Biotin carboxylase C-terminal domain	MA20_04765	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
YHH1_k127_9264279_1	638302.HMPREF0908_1954	7.551e-31	123.0	COG1216@1|root,COG1216@2|Bacteria,1VBEV@1239|Firmicutes,4H53X@909932|Negativicutes	909932|Negativicutes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_9264279_0	1470593.BW43_03834	6.38e-104	349.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,1RYRV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	glycosyl transferase group 1	-	-	-	ko:K13001	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_9279556_1	926550.CLDAP_26360	5.41e-13	82.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9279556_0	1122179.KB890421_gene2565	3.689e-22	111.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,4PM4Q@976|Bacteroidetes	976|Bacteroidetes	UW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
YHH1_k127_9279556_3	1278073.MYSTI_00021	3.238e-09	67.0	2DDPU@1|root,2ZIUJ@2|Bacteria,1Q3VS@1224|Proteobacteria,439PU@68525|delta/epsilon subdivisions,2X51N@28221|Deltaproteobacteria,2YZZK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9304538_3	278963.ATWD01000002_gene856	1.009e-48	180.0	COG0311@1|root,COG0311@2|Bacteria,3Y4GN@57723|Acidobacteria,2JJ3V@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
YHH1_k127_9304538_1	1382306.JNIM01000001_gene701	2.085e-91	310.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
YHH1_k127_9304538_2	1379698.RBG1_1C00001G1880	3.565e-70	249.0	COG0761@1|root,COG0761@2|Bacteria,2NP7K@2323|unclassified Bacteria	2|Bacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	iIT341.HP0400,iLJ478.TM1444	LYTB,S1
YHH1_k127_9304538_0	1379698.RBG1_1C00001G1882	7.949e-117	386.0	COG1138@1|root,COG1138@2|Bacteria,2NNYV@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
YHH1_k127_931712_2	247490.KSU1_C0714	3.128e-136	473.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
YHH1_k127_931712_20	1117647.M5M_06680	3.554e-06	61.0	COG5183@1|root,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,1J519@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	A	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
YHH1_k127_931712_12	56110.Oscil6304_3724	3.004e-43	183.0	COG0689@1|root,COG2931@1|root,COG3391@1|root,COG5184@1|root,COG0689@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
YHH1_k127_931712_0	1379698.RBG1_1C00001G0445	0.0	1236.0	COG0542@1|root,COG0542@2|Bacteria,2NNKN@2323|unclassified Bacteria	2|Bacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YHH1_k127_931712_3	1379698.RBG1_1C00001G0446	4.69e-120	395.0	COG3869@1|root,COG3869@2|Bacteria,2NR28@2323|unclassified Bacteria	2|Bacteria	E	ATP:guanido phosphotransferase, C-terminal catalytic domain	mcsB	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	2.7.14.1,2.7.3.2,2.7.3.3	ko:K00933,ko:K00934,ko:K19405	ko00330,ko01100,map00330,map01100	M00047	R00554,R01881,R11090	RC00002,RC00203	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ATP-gua_Ptrans
YHH1_k127_931712_11	1379698.RBG1_1C00001G0447	1.103e-47	177.0	COG3880@1|root,COG3880@2|Bacteria,2NRIE@2323|unclassified Bacteria	2|Bacteria	S	UvrB/uvrC motif	CP_0046	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	GSu_C4xC__C2xCH,UVR
YHH1_k127_931712_7	861299.J421_3214	8.871e-68	237.0	COG1136@1|root,COG1136@2|Bacteria,1ZSNF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
YHH1_k127_931712_4	1379698.RBG1_1C00001G0449	8.245e-97	330.0	COG4591@1|root,COG4591@2|Bacteria,2NP18@2323|unclassified Bacteria	2|Bacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
YHH1_k127_931712_1	333138.LQ50_21875	2.258e-171	552.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,1ZAVI@1386|Bacillus	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YHH1_k127_931712_16	1173027.Mic7113_2654	1.866e-28	122.0	COG1670@1|root,COG1670@2|Bacteria,1G6F2@1117|Cyanobacteria	1117|Cyanobacteria	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YHH1_k127_931712_17	63737.Npun_R1490	6.398e-11	74.0	2BDP7@1|root,327CQ@2|Bacteria,1GCJ7@1117|Cyanobacteria,1HMVV@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_931712_10	1379281.AVAG01000009_gene607	7.433e-53	194.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2MBFU@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YHH1_k127_931712_19	743719.PaelaDRAFT_2201	2.412e-07	59.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,26X94@186822|Paenibacillaceae	91061|Bacilli	L	DNA uptake protein and related DNA-binding proteins	comEA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
YHH1_k127_931712_22	511051.CSE_11910	0.0001643	51.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_N,NTP_transf_3
YHH1_k127_931712_15	1379698.RBG1_1C00001G0548	7.302e-29	123.0	COG3117@1|root,COG3117@2|Bacteria,2NQ8Q@2323|unclassified Bacteria	2|Bacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K09774,ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
YHH1_k127_931712_8	1379698.RBG1_1C00001G0547	9.093e-66	235.0	COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria	2|Bacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
YHH1_k127_931712_9	1278073.MYSTI_05554	3.171e-58	209.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,42TJI@68525|delta/epsilon subdivisions,2WQM5@28221|Deltaproteobacteria,2Z313@29|Myxococcales	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
YHH1_k127_931712_5	1379698.RBG1_1C00001G0545	1.459e-95	323.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,2NNNB@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	2.5.1.55,5.3.1.13	ko:K01627,ko:K03281,ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530,R03254	RC00435,RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	2.A.49	-	iAF987.Gmet_1278	CBS,SIS
YHH1_k127_931712_13	28258.KP05_04425	1.66e-37	147.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1XJXX@135619|Oceanospirillales	135619|Oceanospirillales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_3
YHH1_k127_931712_6	1191523.MROS_0384	3.88e-90	308.0	COG2877@1|root,COG2877@2|Bacteria	2|Bacteria	M	3-deoxy-8-phosphooctulonate synthase activity	kdsA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
YHH1_k127_931712_21	1121468.AUBR01000037_gene1353	4.7e-05	50.0	COG1657@1|root,COG1657@2|Bacteria,1UY4I@1239|Firmicutes,24E8I@186801|Clostridia,42EWE@68295|Thermoanaerobacterales	186801|Clostridia	I	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430,SLH
YHH1_k127_931712_18	42256.RradSPS_0047	8.102e-11	72.0	2DFV5@1|root,2ZT9W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9327361_3	485913.Krac_8040	1.068e-33	141.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	DA1-like,GAF,Guanylate_cyc,HAMP,PAS_4,PAS_9,Response_reg,dCache_1
YHH1_k127_9327361_4	234267.Acid_3550	1.453e-22	105.0	COG3832@1|root,COG3832@2|Bacteria,3Y7RQ@57723|Acidobacteria	57723|Acidobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YHH1_k127_9327361_0	690850.Desaf_1745	4.564e-61	214.0	COG1981@1|root,COG1981@2|Bacteria,1NM81@1224|Proteobacteria,42Y3M@68525|delta/epsilon subdivisions,2WSK7@28221|Deltaproteobacteria,2MBAP@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9327361_2	658086.HMPREF0994_02487	7.433e-36	148.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,249SD@186801|Clostridia,27JBA@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Nitroreductase family	-	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
YHH1_k127_9327361_1	926560.KE387023_gene3415	6.691e-38	150.0	COG0454@1|root,COG0454@2|Bacteria,1WMP9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
YHH1_k127_9336558_1	396588.Tgr7_2677	2.219e-29	118.0	COG1628@1|root,COG1628@2|Bacteria,1RCX1@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF99	-	-	-	ko:K09120	-	-	-	-	ko00000	-	-	-	DUF99
YHH1_k127_9336558_0	1132855.KB913035_gene1498	6.474e-197	620.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,2KKTT@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
YHH1_k127_9379062_3	580340.Tlie_1826	3.056e-18	86.0	COG0677@1|root,COG0677@2|Bacteria,3T9YU@508458|Synergistetes	508458|Synergistetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH1_k127_9379062_5	1125863.JAFN01000001_gene3054	3.308e-11	77.0	COG1413@1|root,COG1413@2|Bacteria,1NR1B@1224|Proteobacteria	1224|Proteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
YHH1_k127_9379062_0	1379698.RBG1_1C00001G0230	3.351e-103	353.0	COG2206@1|root,COG2206@2|Bacteria,2NPP4@2323|unclassified Bacteria	2|Bacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
YHH1_k127_9379062_7	331678.Cphamn1_2085	1.623e-07	61.0	28PR3@1|root,303J8@2|Bacteria,1FFJ0@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9379062_4	1082931.KKY_567	1.215e-17	94.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2TT5I@28211|Alphaproteobacteria,3N9IA@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
YHH1_k127_9379062_1	1379698.RBG1_1C00001G1327	8.641e-92	310.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
YHH1_k127_9379062_2	1001585.MDS_1229	2.29e-68	244.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1YJRS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	transporter MgtE	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
YHH1_k127_9380476_0	309799.DICTH_1910	4.878e-60	214.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
YHH1_k127_9380476_1	448385.sce6624	2.377e-43	173.0	COG2865@1|root,COG2865@2|Bacteria,1RD2Z@1224|Proteobacteria,432K0@68525|delta/epsilon subdivisions,2WY92@28221|Deltaproteobacteria,2Z2HZ@29|Myxococcales	28221|Deltaproteobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
YHH1_k127_9405832_2	1313421.JHBV01000049_gene75	8.365e-66	228.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
YHH1_k127_9405832_0	211165.AJLN01000116_gene3208	6.873e-104	353.0	COG4325@1|root,COG4325@2|Bacteria,1G2Y0@1117|Cyanobacteria,1JKD6@1189|Stigonemataceae	1117|Cyanobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
YHH1_k127_9405832_3	1121904.ARBP01000006_gene3740	9.74e-41	156.0	COG0457@1|root,COG0457@2|Bacteria,4PBAK@976|Bacteroidetes,47VJ2@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9405832_4	1455608.JDTH01000002_gene176	1.365e-32	130.0	arCOG09236@1|root,arCOG09236@2157|Archaea,2XYRW@28890|Euryarchaeota,23X7P@183963|Halobacteria	183963|Halobacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9405832_1	485913.Krac_4939	4.647e-86	293.0	COG2120@1|root,COG2120@2|Bacteria,2G9IP@200795|Chloroflexi	200795|Chloroflexi	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YHH1_k127_9405832_5	869210.Marky_1927	4.397e-08	59.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
YHH1_k127_9410201_6	745411.B3C1_05050	1.26e-16	92.0	COG3055@1|root,COG3391@1|root,COG5184@1|root,COG5276@1|root,COG3055@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1QUHA@1224|Proteobacteria,1T1YV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
YHH1_k127_9410201_2	926549.KI421517_gene511	2.547e-148	482.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,47N91@768503|Cytophagia	976|Bacteroidetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
YHH1_k127_9410201_0	1379698.RBG1_1C00001G0688	1.585e-276	861.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
YHH1_k127_9410201_4	1379698.RBG1_1C00001G0687	1.535e-126	420.0	COG1109@1|root,COG1109@2|Bacteria,2NNM3@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YHH1_k127_9410201_5	671143.DAMO_0010	4.303e-76	264.0	COG0483@1|root,COG0483@2|Bacteria,2NP94@2323|unclassified Bacteria	2|Bacteria	G	Inositol monophosphatase	suhB	GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
YHH1_k127_9410201_1	1191523.MROS_1555	2.268e-194	625.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH1_k127_9410201_3	234267.Acid_3848	9.201e-141	467.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
YHH1_k127_9410201_7	292459.STH2747	5.464e-06	59.0	COG1463@1|root,COG2120@1|root,COG1463@2|Bacteria,COG2120@2|Bacteria,1UYPV@1239|Firmicutes,251C1@186801|Clostridia	186801|Clostridia	Q	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YHH1_k127_9446287_1	945713.IALB_0465	4.529e-77	262.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YHH1_k127_9446287_0	1379698.RBG1_1C00001G0202	2.039e-125	407.0	COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YHH1_k127_9446609_5	945713.IALB_1259	1.438e-16	86.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9446609_0	1121920.AUAU01000004_gene859	3.165e-161	516.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria	57723|Acidobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH1_k127_9446609_3	713586.KB900536_gene1207	6.711e-71	249.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,1S2PS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
YHH1_k127_9446609_1	765913.ThidrDRAFT_1551	2.195e-134	450.0	28K0F@1|root,2Z9QE@2|Bacteria,1R5C6@1224|Proteobacteria,1RQFC@1236|Gammaproteobacteria,1WXQC@135613|Chromatiales	135613|Chromatiales	C	PFAM Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
YHH1_k127_9446609_4	290315.Clim_1053	3.328e-37	148.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	chpE	-	-	ko:K06600,ko:K06895	-	-	-	-	ko00000,ko02000,ko02035	2.A.75.1,2.A.76	-	-	LysE
YHH1_k127_9446609_2	1379698.RBG1_1C00001G1315	1.214e-73	255.0	COG0463@1|root,COG0463@2|Bacteria,2NP2G@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
YHH1_k127_945285_5	445335.CBN_2519	1.703e-35	146.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,36E3G@31979|Clostridiaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14365	CM_2,SKI,Shikimate_DH,Shikimate_dh_N
YHH1_k127_945285_6	1408321.JNJD01000006_gene999	3.614e-28	121.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,27K3D@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
YHH1_k127_945285_3	34007.IT40_18310	8.218e-61	224.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,2PVGJ@265|Paracoccus	28211|Alphaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
YHH1_k127_945285_4	370438.PTH_1160	2.87e-47	177.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia,2621A@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
YHH1_k127_945285_2	880073.Calab_0837	8.335e-77	274.0	COG0534@1|root,COG0534@2|Bacteria,2NPBA@2323|unclassified Bacteria	2|Bacteria	V	MATE efflux family protein	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
YHH1_k127_945285_1	309801.trd_0179	2.549e-79	275.0	COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,27XTE@189775|Thermomicrobia	189775|Thermomicrobia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
YHH1_k127_945285_0	706587.Desti_3075	7.067e-80	274.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,42NS5@68525|delta/epsilon subdivisions,2WNQ5@28221|Deltaproteobacteria,2MQFJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
YHH1_k127_9456455_2	1340493.JNIF01000003_gene2186	8.964e-09	59.0	COG1026@1|root,COG1026@2|Bacteria	2|Bacteria	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
YHH1_k127_9456455_1	1121920.AUAU01000007_gene487	5.285e-127	416.0	COG0436@1|root,COG0436@2|Bacteria,3Y2IZ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH1_k127_9456455_0	323259.Mhun_2840	2.546e-129	436.0	COG3291@1|root,arCOG02516@1|root,arCOG03264@1|root,arCOG03606@1|root,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG03264@2157|Archaea,arCOG03606@2157|Archaea,2Y7RP@28890|Euryarchaeota,2NBKZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF3344,PKD
YHH1_k127_9488613_4	1379698.RBG1_1C00001G1332	1.615e-22	98.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
YHH1_k127_9488613_1	1379698.RBG1_1C00001G1333	3.219e-100	352.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	pkn5	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1
YHH1_k127_9488613_2	1379698.RBG1_1C00001G1334	2.672e-85	307.0	COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria	2|Bacteria	I	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
YHH1_k127_9488613_5	1379698.RBG1_1C00001G1335	2.516e-09	71.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9488613_0	552811.Dehly_0815	8.643e-102	340.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi,34CK5@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
YHH1_k127_9488613_3	646529.Desaci_3208	2.383e-83	286.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,2604A@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM metallophosphoesterase, MG_246 BB_0505 family	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
YHH1_k127_9492137_0	865937.Gilli_0418	8.495e-57	221.0	COG3188@1|root,COG3188@2|Bacteria,4NFPY@976|Bacteroidetes,1HXS8@117743|Flavobacteriia,2P5CG@244698|Gillisia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9492137_1	1120965.AUBV01000010_gene2747	9.977e-23	108.0	COG3121@1|root,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PapD_N
YHH1_k127_9512038_3	1232437.KL661966_gene3173	1.261e-22	104.0	COG2133@1|root,COG2133@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9512038_0	335543.Sfum_0899	1.509e-196	627.0	COG0490@1|root,COG0569@1|root,COG1226@1|root,COG0490@2|Bacteria,COG0569@2|Bacteria,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria,42NKU@68525|delta/epsilon subdivisions,2WIRH@28221|Deltaproteobacteria,2MRD0@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
YHH1_k127_9512038_2	243231.GSU1538	6.358e-33	131.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N38@68525|delta/epsilon subdivisions,2WK56@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
YHH1_k127_9512038_1	1122134.KB893650_gene916	8.945e-44	164.0	COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,1S01E@1236|Gammaproteobacteria,1XS4J@135619|Oceanospirillales	135619|Oceanospirillales	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
YHH1_k127_9512038_4	671143.DAMO_0971	2.24e-18	87.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
YHH1_k127_9512038_5	1125863.JAFN01000001_gene3475	2.891e-14	74.0	COG1569@1|root,COG1569@2|Bacteria,1Q9X7@1224|Proteobacteria,42X9V@68525|delta/epsilon subdivisions,2WT2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH1_k127_9512038_6	797303.Natpe_3980	2.726e-11	66.0	COG1569@1|root,arCOG02120@2157|Archaea,2XZ4S@28890|Euryarchaeota,23X68@183963|Halobacteria	183963|Halobacteria	V	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH1_k127_951660_0	1122132.AQYH01000010_gene3973	6.071e-39	151.0	COG5533@1|root,COG5533@2|Bacteria,1ND27@1224|Proteobacteria,2VGYQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Opioid growth factor receptor (OGFr) conserved region	-	-	-	-	-	-	-	-	-	-	-	-	OGFr_N
YHH1_k127_951660_2	1123392.AQWL01000016_gene524	0.0001754	45.0	COG0629@1|root,COG0629@2|Bacteria,1N2SY@1224|Proteobacteria,2VU3J@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM single-strand binding protein Primosomal replication protein n	-	-	-	-	-	-	-	-	-	-	-	-	SSB
YHH1_k127_9531634_3	1286631.X805_27880	1.254e-58	220.0	COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,2VWHG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9531634_6	414684.RC1_4006	1.248e-10	74.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,2TT1Y@28211|Alphaproteobacteria,2JQ8F@204441|Rhodospirillales	204441|Rhodospirillales	DM	Chain length determinant protein	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,Wzz
YHH1_k127_9531634_0	383372.Rcas_0489	7.228e-210	672.0	COG0367@1|root,COG0367@2|Bacteria,2G7R3@200795|Chloroflexi,376WK@32061|Chloroflexia	32061|Chloroflexia	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
YHH1_k127_9531634_1	880073.Calab_1595	1.03e-118	400.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
YHH1_k127_9531634_4	935840.JAEQ01000003_gene93	3.323e-20	93.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,2UU7U@28211|Alphaproteobacteria,43RH9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
YHH1_k127_9531634_2	945713.IALB_2491	1.856e-107	357.0	COG0171@1|root,COG0171@2|Bacteria	2|Bacteria	H	NAD+ synthase (glutamine-hydrolyzing) activity	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
YHH1_k127_9531634_5	1033743.CAES01000085_gene2958	1.146e-11	79.0	COG1404@1|root,COG2730@1|root,COG1404@2|Bacteria,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	celA7	-	3.2.1.4,3.2.1.78	ko:K01179,ko:K01218	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R01332,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH26,GH5,GH9	-	CBM_3,CBM_35,F5_F8_type_C,Glyco_hydro_26,Glyco_hydro_44,Peptidase_S8,SLH,fn3
YHH1_k127_9538683_1	635013.TherJR_2864	7.792e-10	70.0	COG4733@1|root,COG4932@1|root,COG4733@2|Bacteria,COG4932@2|Bacteria,1UTKZ@1239|Firmicutes,253GX@186801|Clostridia	186801|Clostridia	C	SMART Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1,Pur_ac_phosph_N
YHH1_k127_9538683_2	1450525.JATV01000009_gene772	0.0006684	51.0	COG3391@1|root,COG3391@2|Bacteria,4NWE6@976|Bacteroidetes,1I650@117743|Flavobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,SGL
YHH1_k127_9538683_0	1121920.AUAU01000024_gene2388	3.156e-178	597.0	COG3005@1|root,COG3043@1|root,COG3005@2|Bacteria,COG3043@2|Bacteria,3Y4BJ@57723|Acidobacteria	57723|Acidobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YHH1_k127_9540855_1	1163617.SCD_n02528	4.816e-50	195.0	COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,2WGFH@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM porin Gram-negative type	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
YHH1_k127_9540855_2	243231.GSU3274	1.518e-46	172.0	2BVK0@1|root,32QXS@2|Bacteria,1RKSK@1224|Proteobacteria,42ZW3@68525|delta/epsilon subdivisions,2WVED@28221|Deltaproteobacteria,43UVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9540855_3	243231.GSU3268	1.69e-18	88.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,43UAC@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-2	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
YHH1_k127_9540855_0	909663.KI867150_gene302	4.872e-60	216.0	COG2067@1|root,COG2067@2|Bacteria,1N1F4@1224|Proteobacteria,42ZP2@68525|delta/epsilon subdivisions,2WUUM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YHH1_k127_9543385_2	304371.MCP_1300	1.407e-96	323.0	COG1131@1|root,arCOG00194@2157|Archaea,2XVFB@28890|Euryarchaeota,2NARP@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH1_k127_9543385_1	215803.DB30_5113	1.873e-129	427.0	COG0793@1|root,COG0793@2|Bacteria,1RGID@1224|Proteobacteria,4382G@68525|delta/epsilon subdivisions,2X3CI@28221|Deltaproteobacteria,2YVET@29|Myxococcales	28221|Deltaproteobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
YHH1_k127_9543385_3	313606.M23134_01115	3.45e-67	243.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,4NHRI@976|Bacteroidetes,47KP6@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH1_k127_9543385_5	1121481.AUAS01000008_gene2960	6.058e-43	178.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,47JVH@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
YHH1_k127_9543385_6	1122225.AULQ01000004_gene2137	1.407e-34	153.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1HYKS@117743|Flavobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
YHH1_k127_9543385_0	378806.STAUR_7818	9.95e-197	627.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
YHH1_k127_9543385_7	414684.RC1_3454	2.621e-34	136.0	COG0517@1|root,COG0517@2|Bacteria,1NMH1@1224|Proteobacteria,2U9D8@28211|Alphaproteobacteria,2JT6V@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YHH1_k127_9543385_4	247490.KSU1_C1034	1.635e-62	229.0	COG3861@1|root,COG3861@2|Bacteria,2IZRE@203682|Planctomycetes	203682|Planctomycetes	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	PRC
YHH1_k127_9567368_0	234267.Acid_2341	2.976e-82	314.0	COG3055@1|root,COG5306@1|root,COG3055@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	exbB2	-	-	ko:K03561,ko:K12287	-	-	-	-	ko00000,ko02000,ko02044	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,Malectin,MotA_ExbB
YHH1_k127_9567368_2	443143.GM18_0612	2.708e-50	209.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	Cadherin,CarboxypepD_reg,DUF11,SdrD_B
YHH1_k127_9567368_7	316067.Geob_1283	2.752e-17	99.0	COG1361@1|root,COG1404@1|root,COG3210@1|root,COG4625@1|root,COG4886@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Cadherin_3,DUF11,DUF4347,He_PIG,PATR
YHH1_k127_9567368_5	555779.Dthio_PD0758	7.741e-23	101.0	COG2442@1|root,COG2442@2|Bacteria,1P47Y@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YHH1_k127_9567368_3	794903.OPIT5_19320	1.641e-34	136.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
YHH1_k127_9567368_8	391623.TERMP_00457	4.075e-11	66.0	COG1656@1|root,COG2442@1|root,arCOG04290@2157|Archaea,arCOG07520@2157|Archaea,2Y1HG@28890|Euryarchaeota,244W7@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YHH1_k127_9567368_4	1173026.Glo7428_0489	2.91e-26	113.0	COG2442@1|root,COG2442@2|Bacteria,1G9MY@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YHH1_k127_9567368_6	99598.Cal7507_5237	1.197e-18	87.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9567368_9	439235.Dalk_1967	0.0001046	54.0	COG0457@1|root,COG3147@1|root,COG0457@2|Bacteria,COG3147@2|Bacteria,1N5M0@1224|Proteobacteria,42U23@68525|delta/epsilon subdivisions,2WQ2H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_1,TPR_8
YHH1_k127_9567368_1	335543.Sfum_2372	4.393e-79	278.0	COG0535@1|root,COG0535@2|Bacteria,1MYFX@1224|Proteobacteria,42SB0@68525|delta/epsilon subdivisions,2WPF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH1_k127_9586874_1	1384056.N787_12580	4.619e-09	57.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,1X31J@135614|Xanthomonadales	135614|Xanthomonadales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
YHH1_k127_9586874_0	1117108.PAALTS15_02467	2.811e-12	78.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,26R1N@186822|Paenibacillaceae	91061|Bacilli	D	Septum formation initiator	divIVA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
YHH1_k127_960698_0	323848.Nmul_A2514	1.131e-81	297.0	COG5652@1|root,COG5652@2|Bacteria,1QUYG@1224|Proteobacteria,2VMBF@28216|Betaproteobacteria,371NZ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ,Wzy_C
YHH1_k127_960698_1	1131553.JIBI01000008_gene1280	3.119e-52	201.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,2VKT7@28216|Betaproteobacteria,3727E@32003|Nitrosomonadales	28216|Betaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH1_k127_960698_2	1123393.KB891331_gene2860	3.664e-22	100.0	COG4767@1|root,COG4767@2|Bacteria,1N67E@1224|Proteobacteria,2WGZ8@28216|Betaproteobacteria,1KS2I@119069|Hydrogenophilales	119069|Hydrogenophilales	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
YHH1_k127_9684970_7	936375.HMPREF1152_0319	4.68e-22	97.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,3WCZ4@538999|Clostridiales incertae sedis	186801|Clostridia	E	Oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YHH1_k127_9684970_5	868131.MSWAN_2154	2.18e-42	160.0	COG3467@1|root,arCOG00520@2157|Archaea,2Y26T@28890|Euryarchaeota,23PV6@183925|Methanobacteria	183925|Methanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
YHH1_k127_9684970_6	861299.J421_1405	4.721e-23	101.0	2A4E9@1|root,2ZJRI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9684970_3	1379698.RBG1_1C00001G0535	4.263e-65	233.0	COG0266@1|root,COG0266@2|Bacteria,2NPGY@2323|unclassified Bacteria	2|Bacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
YHH1_k127_9684970_1	492774.JQMB01000015_gene1677	4.68e-99	334.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,4B7FG@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
YHH1_k127_9684970_4	1382305.AZUC01000045_gene1415	2.482e-63	231.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,26DBF@186818|Planococcaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
YHH1_k127_9684970_0	1379698.RBG1_1C00001G0265	3.469e-126	415.0	COG0592@1|root,COG0592@2|Bacteria,2NP7D@2323|unclassified Bacteria	2|Bacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338,ko:K03610	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400,ko04812	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
YHH1_k127_9684970_2	935948.KE386495_gene1661	3.886e-74	256.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,42F49@68295|Thermoanaerobacterales	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
YHH1_k127_9695107_2	338963.Pcar_2765	4.74e-65	233.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,43SAR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	larD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3245	FAD-oxidase_C,FAD_binding_4
YHH1_k127_9695107_0	936053.I1C0K4	3.876e-140	458.0	COG0372@1|root,KOG2617@2759|Eukaryota,38CK5@33154|Opisthokonta,3NU5Z@4751|Fungi,1GSDT@112252|Fungi incertae sedis	4751|Fungi	C	Citrate synthase, C-terminal domain	CIT1	GO:0003674,GO:0003824,GO:0004108,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005975,GO:0006081,GO:0006082,GO:0006084,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006139,GO:0006163,GO:0006195,GO:0006520,GO:0006536,GO:0006537,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009060,GO:0009064,GO:0009084,GO:0009109,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0015980,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0032787,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0036440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046356,GO:0046394,GO:0046434,GO:0046483,GO:0046487,GO:0046700,GO:0046912,GO:0051186,GO:0051187,GO:0055086,GO:0055114,GO:0070013,GO:0071704,GO:0072350,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
YHH1_k127_9695107_1	1379698.RBG1_1C00001G1238	1.925e-90	323.0	COG5000@1|root,COG5000@2|Bacteria,2NQEP@2323|unclassified Bacteria	2|Bacteria	T	COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,dCache_1
YHH1_k127_9695107_3	1379698.RBG1_1C00001G0287	1.927e-40	171.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
YHH1_k127_9720099_1	234267.Acid_5456	1.804e-167	540.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH1_k127_9720099_2	945713.IALB_0907	9.049e-63	217.0	COG0048@1|root,COG0048@2|Bacteria	2|Bacteria	J	rRNA binding	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
YHH1_k127_9720099_3	945713.IALB_0908	4.679e-56	199.0	COG0049@1|root,COG0049@2|Bacteria	2|Bacteria	J	rRNA binding	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YHH1_k127_9720099_0	1089550.ATTH01000001_gene2343	1.533e-278	872.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1FIQD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YHH1_k127_9720099_4	1122169.AREN01000056_gene2008	1.092e-14	74.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1JD5X@118969|Legionellales	118969|Legionellales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH1_k127_9722048_0	443143.GM18_0097	3.806e-207	664.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria	1224|Proteobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
YHH1_k127_9722048_1	204669.Acid345_1052	6.351e-128	437.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
YHH1_k127_9753065_0	1379698.RBG1_1C00001G1489	1.862e-192	609.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YHH1_k127_9753065_1	880073.Calab_1434	6.122e-120	396.0	COG0484@1|root,COG0484@2|Bacteria,2NNNG@2323|unclassified Bacteria	2|Bacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH1_k127_9753065_4	203119.Cthe_1320	1.469e-34	144.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,3WGGT@541000|Ruminococcaceae	186801|Clostridia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
YHH1_k127_9753065_3	349161.Dred_2493	3.159e-40	158.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,260UN@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
YHH1_k127_9753065_2	1499967.BAYZ01000074_gene2119	6.042e-62	222.0	COG1989@1|root,COG1989@2|Bacteria,2NPDS@2323|unclassified Bacteria	2|Bacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02236,ko:K02278,ko:K02506,ko:K02654,ko:K10966	-	M00331,M00429	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
YHH1_k127_9807824_2	1167006.UWK_00859	4.735e-30	128.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MJQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
YHH1_k127_9807824_1	1122179.KB890424_gene3600	3.568e-43	175.0	COG3146@1|root,COG3146@2|Bacteria	2|Bacteria	S	Peptidogalycan biosysnthesis/recognition	bioF2	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Acetyltransf_6,Aminotran_1_2,FemAB_like
YHH1_k127_9807824_0	1267535.KB906767_gene5468	4.041e-116	388.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	-	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,KR,PP-binding,PS-DH
YHH1_k127_9807824_3	796940.HMPREF9628_00654	2.953e-17	87.0	COG1032@1|root,COG1032@2|Bacteria,1TRZA@1239|Firmicutes,24B00@186801|Clostridia,25SXJ@186804|Peptostreptococcaceae	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YHH1_k127_9824159_1	56780.SYN_02434	5.834e-43	157.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.5.1.106	ko:K15357	ko00760,ko01120,map00760,map01120	M00622	R09126	RC00323,RC02431	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_3,Abhydrolase_6,Hydrolase_4
YHH1_k127_9824159_0	903818.KI912268_gene775	1.811e-54	216.0	COG0457@1|root,COG2319@1|root,COG0457@2|Bacteria,COG2319@2|Bacteria,3Y5JS@57723|Acidobacteria	57723|Acidobacteria	S	PFAM WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
YHH1_k127_9824159_2	237368.SCABRO_01671	2.542e-33	149.0	2EBX9@1|root,335WM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,VPEP
YHH1_k127_9824159_4	96561.Dole_1792	1.537e-08	68.0	COG1653@1|root,COG4932@1|root,COG1653@2|Bacteria,COG4932@2|Bacteria,1N4S6@1224|Proteobacteria,43BRE@68525|delta/epsilon subdivisions,2X729@28221|Deltaproteobacteria,2MNRP@213118|Desulfobacterales	1224|Proteobacteria	G	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9824159_3	572546.Arcpr_0425	1.231e-15	91.0	arCOG07525@1|root,arCOG07525@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9847095_0	653733.Selin_1355	2.538e-171	557.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
YHH1_k127_9847095_2	1123376.AUIU01000015_gene375	1.903e-111	371.0	COG2201@1|root,COG2201@2|Bacteria,3J0X3@40117|Nitrospirae	40117|Nitrospirae	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
YHH1_k127_9847095_3	1379698.RBG1_1C00001G1275	5.256e-74	265.0	COG3852@1|root,COG3852@2|Bacteria,2NS4D@2323|unclassified Bacteria	2|Bacteria	T	Signal transduction histidine kinase, nitrogen specific, NtrB	atoS	-	2.7.13.3	ko:K07708,ko:K07710,ko:K10942	ko02020,ko05111,map02020,map05111	M00497,M00500,M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_8,PAS_9
YHH1_k127_9847095_1	880072.Desac_0330	3.813e-123	408.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MR37@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_9852155_0	278957.ABEA03000110_gene1319	6.314e-75	267.0	COG0270@1|root,COG0270@2|Bacteria,46XFY@74201|Verrucomicrobia,3K9VN@414999|Opitutae	414999|Opitutae	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
YHH1_k127_9852155_1	1122939.ATUD01000020_gene2175	2.373e-08	60.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,TylF
YHH1_k127_9852666_2	452637.Oter_4607	2.418e-48	177.0	COG3005@1|root,COG3005@2|Bacteria,46T0N@74201|Verrucomicrobia,3K8D9@414999|Opitutae	414999|Opitutae	C	TIGRFAM cytochrome c nitrate reductase, small subunit	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
YHH1_k127_9852666_0	247490.KSU1_B0055	1.131e-202	640.0	COG3303@1|root,COG3303@2|Bacteria,2IYGG@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
YHH1_k127_9852666_3	694431.DESACE_00195	1.446e-23	106.0	COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,42WQ3@68525|delta/epsilon subdivisions,2WS2E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH1_k127_9852666_4	215803.DB30_3835	0.0003264	50.0	28QQ1@1|root,2ZD5J@2|Bacteria,1QPY8@1224|Proteobacteria,439MX@68525|delta/epsilon subdivisions,2X4Z5@28221|Deltaproteobacteria,2YZVK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9852666_1	309801.trd_A0425	4.399e-75	273.0	COG2268@1|root,COG2268@2|Bacteria,2GBEI@200795|Chloroflexi,27Z5S@189775|Thermomicrobia	189775|Thermomicrobia	S	Flotillin	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
YHH1_k127_9871969_1	404589.Anae109_1755	1.82e-120	404.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,43C89@68525|delta/epsilon subdivisions,2X7IN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH1_k127_9871969_8	1340493.JNIF01000004_gene981	3.057e-08	58.0	2E34G@1|root,32Y4J@2|Bacteria,3Y5JB@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9871969_2	1121918.ARWE01000001_gene2193	4.246e-62	223.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,42RMP@68525|delta/epsilon subdivisions,2X5PZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
YHH1_k127_9871969_4	234267.Acid_2701	1.619e-17	90.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
YHH1_k127_9871969_10	1120945.ATUW01000002_gene1719	2.568e-07	61.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4D431@85005|Actinomycetales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_9871969_12	1104324.P186_1340	0.0007567	47.0	arCOG03714@1|root,arCOG03714@2157|Archaea,2XQDX@28889|Crenarchaeota	28889|Crenarchaeota	F	ATP cone domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone
YHH1_k127_9871969_3	1379270.AUXF01000001_gene2611	3.181e-52	192.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,GerE,PocR,Response_reg
YHH1_k127_9871969_9	247490.KSU1_C0877	3.24e-08	57.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_9871969_5	1173023.KE650771_gene40	2.98e-15	83.0	COG1359@1|root,COG1359@2|Bacteria,1G8ZC@1117|Cyanobacteria,1JMBV@1189|Stigonemataceae	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
YHH1_k127_9871969_6	1340493.JNIF01000003_gene4040	2.033e-13	72.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_9871969_0	1499967.BAYZ01000036_gene2418	0.0	1211.0	COG0438@1|root,COG0438@2|Bacteria,2NNZH@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_9880162_5	1121430.JMLG01000002_gene1134	1.644e-64	224.0	arCOG10401@1|root,2ZA7Y@2|Bacteria,1V3TD@1239|Firmicutes,24I7A@186801|Clostridia,261TJ@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9880162_0	1379698.RBG1_1C00001G0069	1.629e-114	407.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NRP6@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CHU_C,FlgD_ig,PKD,Peptidase_S8
YHH1_k127_9880162_6	1121930.AQXG01000007_gene491	2.45e-19	104.0	COG1523@1|root,COG1649@1|root,COG4733@1|root,COG1523@2|Bacteria,COG1649@2|Bacteria,COG4733@2|Bacteria,4NHA4@976|Bacteroidetes,1IQ6P@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48,FlgD_ig
YHH1_k127_9880162_8	243090.RB9779	3.051e-14	85.0	2DRBJ@1|root,32UQT@2|Bacteria,2J3C8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9880162_4	1042163.BRLA_c013830	1.504e-94	319.0	COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,26QRV@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter	mntC	-	-	ko:K11709,ko:K19976	ko02010,map02010	M00319,M00792	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC-3
YHH1_k127_9880162_1	1237149.C900_05808	4.462e-114	384.0	COG1108@1|root,COG1321@1|root,COG1108@2|Bacteria,COG1321@2|Bacteria,4NH3D@976|Bacteroidetes,47MU3@768503|Cytophagia	976|Bacteroidetes	KP	ABC 3 transport family	mntC	-	-	ko:K11708	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3,Fe_dep_repr_C
YHH1_k127_9880162_2	643867.Ftrac_0692	3.873e-108	355.0	COG1121@1|root,COG1121@2|Bacteria,4NHZ9@976|Bacteroidetes,47KSI@768503|Cytophagia	976|Bacteroidetes	P	ATPases associated with a variety of cellular activities	troB	-	3.6.3.35	ko:K11710,ko:K19973	ko02010,map02010	M00319,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC_tran
YHH1_k127_9880162_3	1237149.C900_05810	2.03e-105	351.0	COG0803@1|root,COG0803@2|Bacteria,4NGMC@976|Bacteroidetes,47M6W@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the bacterial solute-binding protein 9 family	mntA	-	-	ko:K09815,ko:K11707	ko02010,map02010	M00242,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
YHH1_k127_9880162_7	509191.AEDB02000002_gene1162	2.845e-15	83.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3WKJ7@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
YHH1_k127_9883121_0	1283300.ATXB01000001_gene1515	4.378e-153	490.0	COG0823@1|root,COG0823@2|Bacteria,1PQSK@1224|Proteobacteria,1S0BS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9883121_1	1283300.ATXB01000001_gene1516	1.529e-140	452.0	COG1216@1|root,COG1216@2|Bacteria,1PGWI@1224|Proteobacteria,1RXHY@1236|Gammaproteobacteria,1XGWQ@135618|Methylococcales	135618|Methylococcales	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_9883121_2	1209072.ALBT01000007_gene2745	8.425e-28	119.0	COG0438@1|root,COG0438@2|Bacteria,1NTXD@1224|Proteobacteria,1SMSD@1236|Gammaproteobacteria,1FGU0@10|Cellvibrio	1236|Gammaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
YHH1_k127_9890188_1	330214.NIDE4251	4.319e-53	189.0	COG1064@1|root,COG1064@2|Bacteria,3J0Y9@40117|Nitrospirae	40117|Nitrospirae	C	Zinc-binding dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH1_k127_9890188_0	330214.NIDE4019	5.802e-258	799.0	COG0008@1|root,COG0008@2|Bacteria,3J0CJ@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH1_k127_9896307_2	1123278.KB893452_gene735	1.706e-22	111.0	COG2801@1|root,COG2801@2|Bacteria,4NWHG@976|Bacteroidetes	976|Bacteroidetes	L	leucine-zipper of insertion element IS481	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve_3
YHH1_k127_9896307_0	926569.ANT_00450	1.173e-47	176.0	COG0394@1|root,COG0394@2|Bacteria,2G6TY@200795|Chloroflexi	200795|Chloroflexi	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_5,LMWPc
YHH1_k127_9896307_3	926569.ANT_27760	7.216e-13	68.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi	200795|Chloroflexi	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
YHH1_k127_9897723_0	1379698.RBG1_1C00001G0995	2.241e-76	280.0	COG5617@1|root,COG5617@2|Bacteria,2NS5H@2323|unclassified Bacteria	2|Bacteria	E	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
YHH1_k127_9897723_1	1313301.AUGC01000008_gene468	3.482e-49	179.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes	976|Bacteroidetes	O	peptidase family M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
YHH1_k127_9904680_0	472759.Nhal_2307	1.458e-150	477.0	COG2519@1|root,COG2519@2|Bacteria,1MXAK@1224|Proteobacteria,1RSIH@1236|Gammaproteobacteria,1WWBV@135613|Chromatiales	135613|Chromatiales	J	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YHH1_k127_9904680_1	1449976.KALB_8624	4.208e-103	345.0	COG0604@1|root,COG0604@2|Bacteria,2HHQ9@201174|Actinobacteria,4E89Q@85010|Pseudonocardiales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
YHH1_k127_990752_5	1009370.ALO_14047	1.521e-14	78.0	COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,4H4WS@909932|Negativicutes	909932|Negativicutes	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	-	-	-	-	-	-	-	-	-	Flg_bb_rod
YHH1_k127_990752_3	555079.Toce_1093	8.16e-35	140.0	COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,24JJW@186801|Clostridia,42GD2@68295|Thermoanaerobacterales	186801|Clostridia	N	Flagellar basal body rod protein	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
YHH1_k127_990752_6	1160707.AJIK01000001_gene170	3.115e-14	76.0	COG1677@1|root,COG1677@2|Bacteria,1VEEY@1239|Firmicutes,4HNZW@91061|Bacilli,26G39@186818|Planococcaceae	91061|Bacilli	N	Flagellar hook-basal body	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
YHH1_k127_990752_2	1191523.MROS_2129	2.343e-100	346.0	COG1766@1|root,COG1766@2|Bacteria	2|Bacteria	N	bacterial-type flagellum-dependent cell motility	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
YHH1_k127_990752_1	203119.Cthe_0466	4.051e-102	342.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia,3WHE9@541000|Ruminococcaceae	186801|Clostridia	N	flagellar motor switch protein	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
YHH1_k127_990752_4	498742.BSPA14S_0289	1.138e-16	90.0	COG1317@1|root,COG1317@2|Bacteria,2J5KZ@203691|Spirochaetes	203691|Spirochaetes	N	Flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
YHH1_k127_990752_0	1410618.JNKI01000009_gene73	7.355e-165	529.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,4H2V3@909932|Negativicutes	909932|Negativicutes	N	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH1_k127_9942093_7	706587.Desti_0133	1.05e-56	203.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42Z1A@68525|delta/epsilon subdivisions,2WU2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
YHH1_k127_9942093_4	1312959.KI914630_gene1715	1.217e-83	289.0	COG0053@1|root,COG0053@2|Bacteria,2GKPR@201174|Actinobacteria,1W8ES@1268|Micrococcaceae	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
YHH1_k127_9942093_9	290340.AAur_3138	3.135e-29	127.0	COG0834@1|root,COG0834@2|Bacteria,2IQ78@201174|Actinobacteria,1W9VC@1268|Micrococcaceae	201174|Actinobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
YHH1_k127_9942093_8	1123368.AUIS01000014_gene2296	3.966e-30	124.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	pchC	-	-	ko:K00406,ko:K20200	ko00190,ko00623,ko01100,ko01120,ko02020,map00190,map00623,map01100,map01120,map02020	M00156	R02675,R11194	RC00769	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
YHH1_k127_9942093_0	1123368.AUIS01000014_gene2295	4.374e-187	597.0	COG2133@1|root,COG2133@2|Bacteria,1RI7V@1224|Proteobacteria	1224|Proteobacteria	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YHH1_k127_9942093_10	517433.PanABDRAFT_2702	5.986e-20	92.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,3W15I@53335|Pantoea	1236|Gammaproteobacteria	S	In Escherichia coli this protein putatively regulates the sodium proton (also pH-independent calcium proton) antiporter chaA	chaB	-	-	ko:K06197	-	-	-	-	ko00000	-	-	-	ChaB
YHH1_k127_9942093_11	399742.Ent638_2331	2.019e-08	59.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,3X2Q1@547|Enterobacter	1236|Gammaproteobacteria	S	ChaB	chaB	-	-	ko:K06197	-	-	-	-	ko00000	-	-	-	ChaB
YHH1_k127_9942093_3	1173028.ANKO01000035_gene3727	3.993e-119	402.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1G0WY@1117|Cyanobacteria,1H8ZY@1150|Oscillatoriales	1117|Cyanobacteria	CE	COG0665 Glycine D-amino acid	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
YHH1_k127_9942093_1	1121033.AUCF01000004_gene5062	6.224e-124	403.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2TRDT@28211|Alphaproteobacteria,2JRNT@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH1_k127_9942093_5	338963.Pcar_2388	7.562e-82	287.0	COG0644@1|root,COG0644@2|Bacteria,1PFC1@1224|Proteobacteria,42VN7@68525|delta/epsilon subdivisions,2WR8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
YHH1_k127_9942093_6	1254432.SCE1572_28585	5.592e-73	255.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WJEC@28221|Deltaproteobacteria,2Z2Y8@29|Myxococcales	28221|Deltaproteobacteria	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
YHH1_k127_9942093_2	123214.PERMA_1630	1.053e-120	396.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YHH1_k127_9942093_12	1089544.KB912942_gene1183	0.000174	53.0	COG0457@1|root,COG0457@2|Bacteria,2IC53@201174|Actinobacteria,4EA5Y@85010|Pseudonocardiales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
YHH1_k127_9948185_0	867845.KI911784_gene362	4.618e-10	73.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8,SLH,fn3
YHH1_k127_9948185_1	1121930.AQXG01000004_gene2867	1.061e-09	72.0	COG1404@1|root,COG4254@1|root,COG1404@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FecR
YHH1_k127_9953390_4	1121878.AUGL01000030_gene3475	3.229e-05	52.0	2B7Y7@1|root,3215B@2|Bacteria,1RKYK@1224|Proteobacteria,1S7CC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	VPA1605	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9953390_1	1237149.C900_02118	5.108e-61	221.0	COG1266@1|root,COG1266@2|Bacteria,4NVAP@976|Bacteroidetes,47SVF@768503|Cytophagia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
YHH1_k127_9953390_0	1231241.Mc24_05110	1.732e-62	221.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH1_k127_9953390_2	1173024.KI912148_gene3735	1.761e-51	184.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	ychN	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
YHH1_k127_9953390_3	1385935.N836_35430	7.301e-22	96.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9955711_8	1353529.M899_1034	7.473e-12	67.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1N3KK@1224|Proteobacteria,42TH7@68525|delta/epsilon subdivisions,2WQ6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,GIY-YIG,HTH_20
YHH1_k127_9955711_3	1379698.RBG1_1C00001G1345	6.352e-174	563.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,SSF,SpoIIE
YHH1_k127_9955711_7	574966.KB898649_gene307	4.321e-13	79.0	2F9S3@1|root,34222@2|Bacteria,1NYI5@1224|Proteobacteria,1SQ58@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9955711_2	880073.Calab_2857	1.184e-174	577.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	DUF2808,Peptidase_S46
YHH1_k127_9955711_1	370438.PTH_1770	1.458e-185	591.0	COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,248RP@186801|Clostridia,26067@186807|Peptococcaceae	186801|Clostridia	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal	-	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
YHH1_k127_9955711_4	1356852.N008_09000	6.274e-80	280.0	COG1409@1|root,COG3419@1|root,COG1409@2|Bacteria,COG3419@2|Bacteria	2|Bacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	3.1.3.2	ko:K02674,ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	-	R00548	RC00017	ko00000,ko00001,ko01000,ko02035,ko02044	-	-	-	CarboxypepD_reg,Metallophos,Neisseria_PilC
YHH1_k127_9955711_0	1519464.HY22_07040	6.005e-194	619.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1FEF9@1090|Chlorobi	1090|Chlorobi	C	electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
YHH1_k127_9955711_9	1123290.AUDQ01000012_gene1723	8.623e-07	56.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli,26FCY@186818|Planococcaceae	91061|Bacilli	P	Belongs to the ArsC family	yusI	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
YHH1_k127_9955711_5	1379698.RBG1_1C00001G0810	1.228e-65	229.0	COG4122@1|root,COG4122@2|Bacteria,2NPV6@2323|unclassified Bacteria	2|Bacteria	S	Methyltransferase domain	yrrM	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
YHH1_k127_9955711_6	1379698.RBG1_1C00001G0683	2.459e-16	83.0	COG2146@1|root,COG2146@2|Bacteria,2NQ38@2323|unclassified Bacteria	2|Bacteria	P	(Rieske (2Fe-2S) domain)	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
YHH1_k127_9955711_10	504472.Slin_1442	1.216e-05	57.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
YHH1_k127_9995335_1	1379698.RBG1_1C00001G1751	4.706e-45	177.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2NP4I@2323|unclassified Bacteria	2|Bacteria	U	Metallo-beta-lactamase superfamily	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
YHH1_k127_9995335_0	1379698.RBG1_1C00001G1752	2.203e-95	329.0	COG0728@1|root,COG0728@2|Bacteria,2NNX8@2323|unclassified Bacteria	2|Bacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
## 3395 queries scanned
## Total time (seconds): 85.86780405044556
## Rate: 39.54 q/s