## Wed Dec 17 02:45:25 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/YHH1_bin.29.fa -m mmseqs --itype genome -o YHH1_bin.29 --output_dir /data/result/bins/wyx/egg/YHH1_bin.29 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YHH1_k127_10009044_2	1191523.MROS_2760	1.1e-44	166.0	COG0042@1|root,COG0042@2|Bacteria	2|Bacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
YHH1_k127_10009044_1	926550.CLDAP_10380	6.708e-59	220.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_10009044_0	85643.Tmz1t_3778	3.363e-103	345.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,2VJ5C@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
YHH1_k127_10024539_0	1121104.AQXH01000001_gene1032	1.699e-74	267.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	-	-	-	ko:K02014,ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.14,3.A.15	-	-	AMIN,DUF1598,Plug,Secretin,Secretin_N,TonB_dep_Rec
YHH1_k127_10024539_1	1191523.MROS_0594	9.901e-27	121.0	2EED7@1|root,3387B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10024539_2	945713.IALB_0558	5.895e-06	55.0	COG3166@1|root,COG3166@2|Bacteria	2|Bacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
YHH1_k127_10027686_1	880073.Calab_0063	9.619e-27	112.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	-	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH1_k127_10027686_0	945713.IALB_1378	3.205e-256	812.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
YHH1_k127_10035717_2	945713.IALB_1372	1.281e-100	348.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y
YHH1_k127_10035717_1	945713.IALB_1371	1.437e-102	346.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10035717_0	945713.IALB_1370	7.584e-257	839.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
YHH1_k127_10035717_4	2055.JNXA01000013_gene2728	3.365e-07	63.0	COG2244@1|root,COG2244@2|Bacteria,2HX3M@201174|Actinobacteria,4GCWI@85026|Gordoniaceae	201174|Actinobacteria	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
YHH1_k127_10035717_3	158822.LH89_00170	1.024e-42	162.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,1S6QU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	GAF domain-containing protein	yebR	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0033745,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
YHH1_k127_10039302_0	194439.CT1558	2.301e-96	334.0	COG4365@1|root,COG4365@2|Bacteria,1FDBC@1090|Chlorobi	1090|Chlorobi	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
YHH1_k127_10071332_2	742767.HMPREF9456_01097	7.458e-21	102.0	COG0791@1|root,COG0791@2|Bacteria,4NMT8@976|Bacteroidetes,2G39D@200643|Bacteroidia,22Y7N@171551|Porphyromonadaceae	976|Bacteroidetes	M	NlpC/P60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
YHH1_k127_10071332_1	316274.Haur_3989	2.45e-76	263.0	COG1215@1|root,COG1215@2|Bacteria,2GA7S@200795|Chloroflexi,3780Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_10071332_0	945713.IALB_3051	1.356e-98	351.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
YHH1_k127_10072274_0	517418.Ctha_1347	9.406e-130	429.0	COG0527@1|root,COG0527@2|Bacteria,1FDBX@1090|Chlorobi	1090|Chlorobi	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
YHH1_k127_10072274_1	323848.Nmul_A0541	3.814e-102	347.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,371R9@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YHH1_k127_10093407_0	1191523.MROS_0432	2.548e-189	605.0	COG0653@1|root,COG0653@2|Bacteria	2|Bacteria	U	protein targeting	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH1_k127_10096536_4	1120983.KB894570_gene1267	6.569e-08	55.0	COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,2TUX2@28211|Alphaproteobacteria,1JNYS@119043|Rhodobiaceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YHH1_k127_10096536_3	278963.ATWD01000001_gene4058	1.373e-13	76.0	COG4783@1|root,COG4783@2|Bacteria,3Y5FY@57723|Acidobacteria,2JJX1@204432|Acidobacteriia	204432|Acidobacteriia	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_17,TPR_19
YHH1_k127_10096536_1	383372.Rcas_4347	7.715e-23	102.0	COG2154@1|root,COG2154@2|Bacteria,2G7GN@200795|Chloroflexi,375ZK@32061|Chloroflexia	32061|Chloroflexia	H	PFAM transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YHH1_k127_10096536_2	671143.DAMO_2277	1.09e-17	85.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	ko:K19165	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
YHH1_k127_10096536_0	518766.Rmar_0977	5.103e-114	389.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1FJ4P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
YHH1_k127_10122676_0	1121930.AQXG01000003_gene2458	8.211e-76	267.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1IPXF@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
YHH1_k127_10122676_2	1501230.ET33_05505	1.819e-22	106.0	COG2318@1|root,COG2318@2|Bacteria,1VB99@1239|Firmicutes,4HNES@91061|Bacilli,26ZFK@186822|Paenibacillaceae	91061|Bacilli	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DinB
YHH1_k127_10122676_1	1270196.JCKI01000001_gene3546	8.814e-38	149.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,1IS8Q@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH1_k127_10122676_3	517418.Ctha_1394	4.221e-19	94.0	COG1595@1|root,COG1595@2|Bacteria,1FE7H@1090|Chlorobi	1090|Chlorobi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_10133204_0	1191523.MROS_2439	6.262e-228	713.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027	CBS,IMPDH,NMO
YHH1_k127_10133204_1	644966.Tmar_1187	7.987e-42	163.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,3WD7A@538999|Clostridiales incertae sedis	186801|Clostridia	E	Creatinase/Prolidase N-terminal domain	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
YHH1_k127_10153628_3	945713.IALB_1629	2.836e-28	118.0	COG0713@1|root,COG0713@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YHH1_k127_10153628_2	1191523.MROS_2373	2.384e-38	149.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YHH1_k127_10153628_1	1191523.MROS_2374	1.688e-70	243.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K03615,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
YHH1_k127_10153628_0	945713.IALB_1626	7.491e-112	368.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00337,ko:K05572	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH1_k127_10170112_0	518766.Rmar_0089	6.181e-109	374.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_10170112_4	1037409.BJ6T_14120	1.009e-05	55.0	COG4307@1|root,COG4307@2|Bacteria,1R8WI@1224|Proteobacteria,2TTNJ@28211|Alphaproteobacteria,3JXG7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
YHH1_k127_10170112_2	1123274.KB899406_gene1128	2.426e-82	283.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH1_k127_10170112_3	96561.Dole_0811	6.346e-16	79.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria,2MJ98@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH1_k127_10170112_1	573413.Spirs_3446	2.488e-101	342.0	COG0842@1|root,COG0842@2|Bacteria,2JA86@203691|Spirochaetes	203691|Spirochaetes	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH1_k127_10200972_0	1485545.JQLW01000013_gene1793	1.132e-127	434.0	COG2887@1|root,COG2887@2|Bacteria,1NH8X@1224|Proteobacteria	1224|Proteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
YHH1_k127_10213049_0	698758.AXY_18820	6.854e-15	87.0	COG2304@1|root,COG2304@2|Bacteria,1TQXZ@1239|Firmicutes,4HB0B@91061|Bacilli	91061|Bacilli	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	GATase1_like,VWA,VWA_2,VWA_3
YHH1_k127_10253832_0	1191523.MROS_2214	3.838e-71	254.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_10253832_1	1463854.JOHT01000007_gene3262	2.734e-14	83.0	COG2265@1|root,COG2265@2|Bacteria,2GK97@201174|Actinobacteria	201174|Actinobacteria	J	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_15,Methyltransf_25
YHH1_k127_10263197_3	644282.Deba_2269	1.105e-15	79.0	COG0640@1|root,COG0640@2|Bacteria,1N19R@1224|Proteobacteria,42TRS@68525|delta/epsilon subdivisions,2WQHU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
YHH1_k127_10263197_0	760192.Halhy_6231	6.125e-155	500.0	COG2211@1|root,COG2211@2|Bacteria,4P0XE@976|Bacteroidetes,1J0AW@117747|Sphingobacteriia	976|Bacteroidetes	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH1_k127_10263197_1	880073.Calab_0917	3.175e-98	330.0	COG3833@1|root,COG3833@2|Bacteria,2NS4S@2323|unclassified Bacteria	2|Bacteria	G	Binding-protein-dependent transport system inner membrane component	malG	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
YHH1_k127_10263197_2	880073.Calab_0918	2.653e-46	168.0	COG1175@1|root,COG1175@2|Bacteria,2NQXK@2323|unclassified Bacteria	2|Bacteria	U	Binding-protein-dependent transport system inner membrane component	malF	-	-	ko:K02025,ko:K15770,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1,SBP_bac_8
YHH1_k127_10277441_0	880073.Calab_1785	9.178e-126	414.0	COG0709@1|root,COG1104@1|root,COG0709@2|Bacteria,COG1104@2|Bacteria,2NNVR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	selD	-	2.7.9.3,2.8.1.7	ko:K01008,ko:K04487	ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122	-	R03595,R07460,R11528,R11529	RC00002,RC01789,RC02313,RC02878	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	AIRS,AIRS_C,Aminotran_5
YHH1_k127_10277441_1	237368.SCABRO_03266	1.895e-35	153.0	COG0451@1|root,COG0451@2|Bacteria,2IYNU@203682|Planctomycetes	203682|Planctomycetes	M	COG0451 Nucleoside-diphosphate-sugar	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH1_k127_10296890_1	1121897.AUGO01000016_gene1060	5.476e-35	155.0	COG4447@1|root,COG4447@2|Bacteria,4PM0K@976|Bacteroidetes,1I2DM@117743|Flavobacteriia,2NV0G@237|Flavobacterium	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_10296890_0	945713.IALB_3118	8.12e-78	291.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
YHH1_k127_10309598_0	1232410.KI421427_gene1286	5.527e-113	376.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,43RYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
YHH1_k127_10309598_1	945713.IALB_3203	4.084e-79	278.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	plpD	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
YHH1_k127_10313936_0	1191523.MROS_1241	7.677e-58	222.0	2DBCF@1|root,2Z8DB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
YHH1_k127_10322345_1	1121468.AUBR01000012_gene2574	8.461e-84	290.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,42EVQ@68295|Thermoanaerobacterales	186801|Clostridia	G	TIGRFAM bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
YHH1_k127_10322345_0	945713.IALB_1728	1.406e-293	930.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
YHH1_k127_10322345_2	1454004.AW11_03150	7.683e-07	61.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,1KQ3U@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
YHH1_k127_10337549_0	330214.NIDE0244	1.924e-73	253.0	COG0602@1|root,COG0602@2|Bacteria,3J0M2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
YHH1_k127_10337549_2	880073.Calab_2510	2.394e-45	171.0	COG0780@1|root,COG0780@2|Bacteria,2NPZV@2323|unclassified Bacteria	2|Bacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
YHH1_k127_10337549_1	1304888.ATWF01000001_gene1089	3.337e-67	234.0	COG0603@1|root,COG0603@2|Bacteria,2GF7G@200930|Deferribacteres	200930|Deferribacteres	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
YHH1_k127_1034366_3	1125701.HMPREF1221_01725	1.073e-05	53.0	COG1262@1|root,COG1262@2|Bacteria,2J7SS@203691|Spirochaetes	203691|Spirochaetes	M	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,FGE-sulfatase,fn3
YHH1_k127_1034366_0	880073.Calab_3054	4.727e-71	245.0	COG1839@1|root,COG1839@2|Bacteria,2NPAQ@2323|unclassified Bacteria	2|Bacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
YHH1_k127_1034366_1	945713.IALB_1529	9.258e-49	188.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
YHH1_k127_1034366_2	1501391.LG35_03945	1.457e-29	129.0	COG1215@1|root,COG1215@2|Bacteria,4NFUA@976|Bacteroidetes,2FPUN@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
YHH1_k127_10345205_1	945713.IALB_0618	2.911e-48	185.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH1_k127_10345205_0	945713.IALB_0619	9.238e-67	235.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
YHH1_k127_10346772_1	309807.SRU_2193	2.806e-89	308.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1FJBY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	MgtE intracellular N domain	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
YHH1_k127_10346772_2	1211114.ALIP01000098_gene1836	4.333e-50	190.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1X38K@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YHH1_k127_10346772_0	880073.Calab_0470	8.931e-144	469.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
YHH1_k127_10346772_3	903818.KI912269_gene521	1.634e-24	104.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1,PTR2
YHH1_k127_10357569_0	945713.IALB_2396	1.418e-99	348.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Sortilin-Vps10
YHH1_k127_10361383_3	1125863.JAFN01000001_gene534	4.333e-41	160.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH1_k127_10361383_2	945713.IALB_0761	1.51e-53	199.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
YHH1_k127_10361383_1	945713.IALB_0760	1.15e-79	286.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6,DUF4309,DUF5301
YHH1_k127_10361383_0	1191523.MROS_0284	1.85e-82	288.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
YHH1_k127_10361383_4	1191523.MROS_0285	8.111e-08	53.0	2E09V@1|root,32VXB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10367769_0	945713.IALB_1275	7.207e-21	107.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
YHH1_k127_10367769_1	546271.Selsp_0124	2.036e-14	74.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,4H2UQ@909932|Negativicutes	909932|Negativicutes	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
YHH1_k127_10367936_3	1140.Synpcc7942_2142	7.272e-18	87.0	COG0023@1|root,COG0023@2|Bacteria,1G6P3@1117|Cyanobacteria,1H0SE@1129|Synechococcus	1117|Cyanobacteria	J	Translation initiation factor	sui1	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
YHH1_k127_10367936_2	1541065.JRFE01000025_gene1992	1.433e-51	193.0	COG2602@1|root,COG2602@2|Bacteria,1FZZV@1117|Cyanobacteria,3VJBN@52604|Pleurocapsales	1117|Cyanobacteria	V	Penicillin binding protein transpeptidase domain	-	-	3.5.2.6	ko:K17838	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Transpeptidase
YHH1_k127_10367936_1	342949.PNA2_1651	9.684e-53	199.0	COG2355@1|root,arCOG04083@2157|Archaea,2XUXV@28890|Euryarchaeota,242R0@183968|Thermococci	183968|Thermococci	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
YHH1_k127_10367936_0	926550.CLDAP_04170	4.496e-101	341.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi	200795|Chloroflexi	E	PFAM alanine racemase domain protein	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
YHH1_k127_10385441_1	886293.Sinac_5248	4.452e-08	61.0	COG2804@1|root,COG2804@2|Bacteria,2IXVD@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
YHH1_k127_10385441_0	1142394.PSMK_14630	1.317e-98	334.0	COG2805@1|root,COG2805@2|Bacteria,2IX6Y@203682|Planctomycetes	203682|Planctomycetes	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH1_k127_10385648_3	243231.GSU1773	1.323e-27	119.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,43SYX@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
YHH1_k127_10385648_2	929556.Solca_3097	3.959e-31	129.0	COG2905@1|root,COG2905@2|Bacteria,4NP1Y@976|Bacteroidetes,1ISY1@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YHH1_k127_10385648_0	756499.Desde_4144	2.79e-85	295.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,26028@186807|Peptococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
YHH1_k127_10385648_1	517418.Ctha_0175	1.541e-73	250.0	COG1883@1|root,COG1883@2|Bacteria,1FEQK@1090|Chlorobi	1090|Chlorobi	C	PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
YHH1_k127_10387936_1	945713.IALB_0884	1.823e-11	77.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_10387936_0	316067.Geob_1583	5.222e-42	175.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
YHH1_k127_10393168_2	335543.Sfum_2571	3.45e-49	182.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42UDS@68525|delta/epsilon subdivisions,2WPGE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
YHH1_k127_10393168_0	1121918.ARWE01000001_gene2511	9.226e-201	636.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,43SUM@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	pyridine nucleotide-disulphide oxidoreductase dimerisation region	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
YHH1_k127_10393168_1	867845.KI911784_gene2298	1.748e-119	394.0	COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi,376Q6@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
YHH1_k127_1040077_1	459349.CLOAM0275	1.979e-47	184.0	COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria	2|Bacteria	C	lyase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
YHH1_k127_1040077_0	945713.IALB_2612	1.926e-219	691.0	COG0423@1|root,COG0423@2|Bacteria	2|Bacteria	J	glycyl-tRNA aminoacylation	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
YHH1_k127_10404653_1	1265313.HRUBRA_01224	1.085e-26	114.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,1J6X8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	small membrane protein	ygdD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF423
YHH1_k127_10404653_0	319225.Plut_1496	6.72e-58	211.0	COG1947@1|root,COG1947@2|Bacteria,1FDN3@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YHH1_k127_1041216_1	1121405.dsmv_1623	4.15e-11	64.0	COG0306@1|root,COG0306@2|Bacteria,1QAR3@1224|Proteobacteria,42P0C@68525|delta/epsilon subdivisions,2WJWM@28221|Deltaproteobacteria,2MINM@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Phosphate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
YHH1_k127_1041216_0	1191523.MROS_1319	3.726e-193	627.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
YHH1_k127_1041617_2	631454.N177_2706	6.575e-11	68.0	COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,2TQTX@28211|Alphaproteobacteria,1JNX0@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	Inositol monophosphatase family	hisN	-	3.1.3.15,3.1.3.25,3.1.3.93	ko:K01092,ko:K18649	ko00053,ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00053,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00114,M00131	R01185,R01186,R01187,R03013,R07674	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YHH1_k127_1041617_0	395961.Cyan7425_1067	2.776e-51	192.0	COG1704@1|root,COG1704@2|Bacteria,1G5F1@1117|Cyanobacteria,3KJH2@43988|Cyanothece	1117|Cyanobacteria	S	E3 Ubiquitin ligase	-	-	-	-	-	-	-	-	-	-	-	-	GIDE
YHH1_k127_1041617_1	521719.ATXQ01000002_gene2429	1.205e-49	183.0	2AQI0@1|root,31FQP@2|Bacteria,1RI31@1224|Proteobacteria,1TAV2@1236|Gammaproteobacteria,1YGKQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10420740_0	1123399.AQVE01000027_gene1	4.401e-51	200.0	COG0823@1|root,COG1800@1|root,COG0823@2|Bacteria,COG1800@2|Bacteria,1R2PF@1224|Proteobacteria,1T5UY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10420740_1	945713.IALB_1599	2.384e-44	179.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
YHH1_k127_10426975_1	1047013.AQSP01000115_gene357	1.436e-31	126.0	COG1866@1|root,COG1866@2|Bacteria,2NQCF@2323|unclassified Bacteria	2|Bacteria	C	Phosphoenolpyruvate carboxykinase	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
YHH1_k127_10426975_0	1047013.AQSP01000115_gene356	3.432e-229	723.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
YHH1_k127_10430022_0	945713.IALB_2071	7.353e-236	744.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
YHH1_k127_10432680_0	1089550.ATTH01000001_gene445	2.321e-35	145.0	2B2YN@1|root,31VJM@2|Bacteria,4NXAT@976|Bacteroidetes,1FJGE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10469427_1	318161.Sden_0578	1.111e-14	79.0	COG3682@1|root,COG3682@2|Bacteria,1RHX7@1224|Proteobacteria,1S5UV@1236|Gammaproteobacteria,2QC5H@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Transcriptional repressor, CopY family	blaI	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YHH1_k127_10469427_0	1191523.MROS_0148	5.652e-100	341.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
YHH1_k127_10473188_0	1232410.KI421421_gene3647	8.684e-221	704.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,43T79@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH1_k127_10473188_2	1191523.MROS_0026	4.144e-65	237.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
YHH1_k127_10473188_1	1304275.C41B8_04951	2.745e-98	332.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
YHH1_k127_10480079_2	330214.NIDE0254	3.261e-117	388.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH1_k127_10480079_0	1047013.AQSP01000142_gene190	4.354e-169	545.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	putP_2	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
YHH1_k127_10480079_1	945713.IALB_1601	2.83e-148	480.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	sulP	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	iSbBS512_1146.SbBS512_E1370	STAS,Sulfate_transp
YHH1_k127_10487205_2	1123508.JH636441_gene3259	6.487e-22	97.0	COG0745@1|root,COG0745@2|Bacteria,2J2U8@203682|Planctomycetes	203682|Planctomycetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH1_k127_10487205_0	118163.Ple7327_0740	6.716e-111	380.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1G3J0@1117|Cyanobacteria,3VM91@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
YHH1_k127_10487205_1	468059.AUHA01000006_gene2981	9.131e-97	319.0	COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,1IWQ1@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
YHH1_k127_10496346_0	1313301.AUGC01000005_gene315	1.398e-161	515.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
YHH1_k127_10496346_1	1124780.ANNU01000013_gene3851	7.648e-24	109.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,47PY8@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit III	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
YHH1_k127_10535395_1	857293.CAAU_0042	8.473e-91	307.0	COG0451@1|root,COG0451@2|Bacteria,1TSUN@1239|Firmicutes,2485S@186801|Clostridia,36FJ8@31979|Clostridiaceae	186801|Clostridia	M	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YHH1_k127_10535395_0	929713.NIASO_14645	8.41e-170	542.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1IP7S@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_10535395_2	518766.Rmar_2601	3.247e-09	61.0	COG0457@1|root,COG0457@2|Bacteria,4PM6F@976|Bacteroidetes,1FJ20@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
YHH1_k127_10537906_0	1121930.AQXG01000001_gene1166	1.004e-11	78.0	COG1404@1|root,COG1404@2|Bacteria,4NVH2@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10573502_1	518766.Rmar_0189	1.061e-34	140.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1FJCG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
YHH1_k127_10573502_0	1089553.Tph_c25450	1.876e-98	336.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,42F28@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH1_k127_10597595_3	694427.Palpr_1797	2.278e-08	55.0	COG0526@1|root,COG0526@2|Bacteria,4NUP1@976|Bacteroidetes,2FUJZ@200643|Bacteroidia,22YRN@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Redox-active disulfide protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
YHH1_k127_10597595_2	1168034.FH5T_14815	1.485e-16	86.0	2E9PV@1|root,333W7@2|Bacteria,4NT8I@976|Bacteroidetes,2FT1D@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10597595_1	694427.Palpr_1799	1.176e-92	309.0	COG0785@1|root,COG0785@2|Bacteria,4PKGI@976|Bacteroidetes,2G3GF@200643|Bacteroidia,231NH@171551|Porphyromonadaceae	976|Bacteroidetes	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
YHH1_k127_10597595_0	1191523.MROS_1066	3.259e-169	540.0	COG0701@1|root,COG0701@2|Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
YHH1_k127_10608129_1	945713.IALB_0228	1.889e-127	411.0	COG0113@1|root,COG0113@2|Bacteria	2|Bacteria	H	porphobilinogen synthase activity	hemB	GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iECABU_c1320.ECABU_c04500,iEcSMS35_1347.EcSMS35_0398,iJN746.PP_2913,ic_1306.c0477	ALAD
YHH1_k127_10608129_2	1005999.GLGR_1103	1.862e-41	163.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0502 family	yceH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
YHH1_k127_10608129_0	1125863.JAFN01000001_gene2915	5.502e-175	558.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2WJQ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH1_k127_10611190_1	1484460.JSWG01000008_gene1892	2.466e-126	426.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HZIA@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
YHH1_k127_10611190_0	1191523.MROS_2233	3.552e-145	469.0	COG0205@1|root,COG0205@2|Bacteria	2|Bacteria	G	6-phosphofructokinase activity	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
YHH1_k127_10623198_0	945713.IALB_0147	1.097e-47	188.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
YHH1_k127_10624457_3	1089550.ATTH01000001_gene2106	2.37e-10	66.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,1FIXN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycogen debranching enzyme, glucanotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
YHH1_k127_10624457_1	1521187.JPIM01000061_gene994	3.004e-75	276.0	COG0642@1|root,COG2205@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
YHH1_k127_10624457_2	1167006.UWK_00678	1.763e-48	185.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMP4@28221|Deltaproteobacteria,2MJMR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
YHH1_k127_10624457_0	765952.PUV_09940	5.561e-161	516.0	COG0380@1|root,COG0380@2|Bacteria,2JFMV@204428|Chlamydiae	204428|Chlamydiae	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
YHH1_k127_10624938_1	880073.Calab_2777	1.786e-08	66.0	COG1361@1|root,COG2356@1|root,COG1361@2|Bacteria,COG2356@2|Bacteria,2NQUF@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease I	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Endonuclease_1,Exo_endo_phos,FlgD_ig,Fn3-like,LTD
YHH1_k127_10624938_0	1123057.P872_04430	3.468e-29	135.0	COG2885@1|root,COG2885@2|Bacteria,4NI1Y@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2,OmpA
YHH1_k127_10632384_0	517418.Ctha_0342	9.155e-10	70.0	COG0737@1|root,COG3391@1|root,COG0737@2|Bacteria,COG3391@2|Bacteria,1FDAF@1090|Chlorobi	1090|Chlorobi	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase,SWM_repeat
YHH1_k127_10632940_1	880073.Calab_3585	4.761e-41	166.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4,2.7.11.1	ko:K02945,ko:K03527,ko:K12132	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011	-	-	-	S1
YHH1_k127_10632940_0	697281.Mahau_0741	5.282e-156	505.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,42EXS@68295|Thermoanaerobacterales	186801|Clostridia	E	M3B, thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YHH1_k127_10642383_0	261292.Nit79A3_2521	8.23e-208	659.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,3727F@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
YHH1_k127_1064581_0	945713.IALB_2161	1.397e-95	334.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_10654988_1	383372.Rcas_1364	2.446e-55	199.0	COG1905@1|root,COG1905@2|Bacteria,2G6Q5@200795|Chloroflexi,37775@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
YHH1_k127_10654988_0	857293.CAAU_0207	8.584e-225	710.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,36EMP@31979|Clostridiaceae	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	hymB	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00335,ko:K18331,ko:K22339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
YHH1_k127_10664580_3	1463936.JOJI01000065_gene7061	9.872e-09	66.0	28JCJ@1|root,2Z977@2|Bacteria,2GJVA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
YHH1_k127_10664580_1	1463879.JOHP01000029_gene4935	1.424e-57	208.0	COG1131@1|root,COG1131@2|Bacteria,2GP3F@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH1_k127_10664580_2	1485544.JQKP01000002_gene1494	1.964e-31	135.0	COG4221@1|root,COG4221@2|Bacteria,1QTVZ@1224|Proteobacteria,2WGPF@28216|Betaproteobacteria,44UYR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH1_k127_10664580_0	349124.Hhal_1473	1.129e-231	750.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,1T62S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
YHH1_k127_106831_2	765952.PUV_16270	3.114e-09	61.0	COG2947@1|root,COG2947@2|Bacteria,2JH2Z@204428|Chlamydiae	204428|Chlamydiae	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
YHH1_k127_106831_1	1499967.BAYZ01000082_gene1016	2.603e-23	110.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	yihX	GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.10,3.1.3.104,3.8.1.2	ko:K01560,ko:K07025,ko:K20866,ko:K21063	ko00010,ko00361,ko00625,ko00740,ko01100,ko01110,ko01120,map00010,map00361,map00625,map00740,map01100,map01110,map01120	M00125	R00947,R05287,R07280	RC00017,RC00078,RC00697	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
YHH1_k127_106831_0	945713.IALB_2658	1.33e-30	131.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH1_k127_10690574_0	929556.Solca_1899	2.111e-85	290.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPCA@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_10690574_1	700598.Niako_0423	2.808e-44	163.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1IPEF@117747|Sphingobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
YHH1_k127_10693359_3	504487.JCM19302_1730	3.419e-21	99.0	COG2897@1|root,COG2897@2|Bacteria,4NKP3@976|Bacteroidetes,1I03P@117743|Flavobacteriia	976|Bacteroidetes	M	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH1_k127_10693359_1	880073.Calab_1603	3.499e-75	271.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH1_k127_10693359_0	1191523.MROS_2298	5.872e-93	312.0	COG1694@1|root,COG3956@2|Bacteria	2|Bacteria	E	TIGRFAM MazG family protein	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66,3.6.1.9	ko:K02428,ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	iJN678.sll1005	MazG
YHH1_k127_10693359_2	1120999.JONM01000017_gene63	2.867e-57	206.0	COG3644@1|root,COG3644@2|Bacteria,1RK12@1224|Proteobacteria,2VRFE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2239)	-	-	-	ko:K09965	-	-	-	-	ko00000	-	-	-	DUF2239
YHH1_k127_10693387_0	1408813.AYMG01000032_gene5239	3.118e-59	230.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IR0W@117747|Sphingobacteriia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,SASA,SprB
YHH1_k127_10708437_0	234267.Acid_1673	3.707e-60	220.0	COG0332@1|root,COG0332@2|Bacteria,3Y83G@57723|Acidobacteria	57723|Acidobacteria	H	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C
YHH1_k127_10708437_3	1168289.AJKI01000004_gene2926	4.379e-10	64.0	COG2827@1|root,COG2827@2|Bacteria,4P9EH@976|Bacteroidetes,2FZ8T@200643|Bacteroidia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH1_k127_10708437_5	693977.Deipr_0346	6.875e-05	55.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP,PKD
YHH1_k127_10708437_2	935863.AWZR01000002_gene837	4.25e-12	74.0	COG1476@1|root,COG1476@2|Bacteria,1N7BB@1224|Proteobacteria,1SCG8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
YHH1_k127_10708437_1	1121930.AQXG01000005_gene710	5.557e-15	78.0	COG2197@1|root,COG2197@2|Bacteria,4NN0B@976|Bacteroidetes,1IZ64@117747|Sphingobacteriia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_10719194_0	290315.Clim_0820	3.578e-120	406.0	COG4775@1|root,COG4775@2|Bacteria,1FDNH@1090|Chlorobi	1090|Chlorobi	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
YHH1_k127_10737339_0	880073.Calab_0965	3.994e-157	501.0	COG0112@1|root,COG0112@2|Bacteria,2NP28@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_3081,iIT341.HP0183	SHMT
YHH1_k127_10737339_2	485917.Phep_3859	3.333e-24	103.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1IPUW@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
YHH1_k127_10737339_3	99598.Cal7507_5897	2.508e-13	81.0	COG1216@1|root,COG1216@2|Bacteria,1G346@1117|Cyanobacteria,1HIR4@1161|Nostocales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_10737339_1	59374.Fisuc_0800	1.008e-40	160.0	COG2265@1|root,COG2265@2|Bacteria	2|Bacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_U5-meth_tr
YHH1_k127_10740464_1	404589.Anae109_2098	1.336e-28	121.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YUPG@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH1_k127_10740464_2	945713.IALB_1763	2.936e-24	108.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.13,3.6.1.55,3.6.1.67	ko:K01515,ko:K03574,ko:K08310	ko00230,ko00790,map00230,map00790	M00126	R01054,R04638	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	NUDIX
YHH1_k127_10740464_3	335543.Sfum_2035	1.1e-08	65.0	COG1716@1|root,COG1716@2|Bacteria,1RGIT@1224|Proteobacteria,43BCI@68525|delta/epsilon subdivisions,2WQHE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
YHH1_k127_10740464_0	1519464.HY22_12070	6.195e-90	307.0	COG1420@1|root,COG1420@2|Bacteria,1FDKF@1090|Chlorobi	1090|Chlorobi	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
YHH1_k127_10756557_1	1120949.KB903317_gene1643	4.221e-19	103.0	COG2133@1|root,COG3291@1|root,COG3506@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,2HEMB@201174|Actinobacteria,4DA70@85008|Micromonosporales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PA14,PKD
YHH1_k127_10756557_0	153721.MYP_2602	2.803e-112	396.0	COG1572@1|root,COG2931@1|root,COG3227@1|root,COG3266@1|root,COG3291@1|root,COG4447@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
YHH1_k127_1077139_1	945713.IALB_0906	2.762e-103	342.0	COG0086@1|root,COG0086@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH1_k127_1077139_2	945713.IALB_0907	3.062e-61	213.0	COG0048@1|root,COG0048@2|Bacteria	2|Bacteria	J	rRNA binding	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
YHH1_k127_1077139_3	945713.IALB_0908	3.687e-57	204.0	COG0049@1|root,COG0049@2|Bacteria	2|Bacteria	J	rRNA binding	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YHH1_k127_1077139_0	945713.IALB_0909	0.0	1078.0	COG0480@1|root,COG0480@2|Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YHH1_k127_1077139_4	945713.IALB_0910	3.487e-34	132.0	COG0050@1|root,COG0050@2|Bacteria	2|Bacteria	J	translation elongation factor activity	tuf	GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484	-	ko:K02358,ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	3.A.1.1.16,3.A.1.1.2	-	iSB619.SA_RS02960	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH1_k127_10789641_2	1121104.AQXH01000001_gene2130	4.681e-62	221.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1IPJE@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_2	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
YHH1_k127_10789641_1	243231.GSU2269	1.1e-71	250.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,43SYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
YHH1_k127_10789641_3	945713.IALB_0736	0.0005953	46.0	291W5@1|root,2ZPFW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10789641_0	517418.Ctha_0775	2.753e-118	400.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,1FDC1@1090|Chlorobi	1090|Chlorobi	EG	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
YHH1_k127_10792787_1	697303.Thewi_0274	4.633e-10	66.0	COG5653@1|root,COG5653@2|Bacteria,1V121@1239|Firmicutes,24E4Q@186801|Clostridia,42FZC@68295|Thermoanaerobacterales	186801|Clostridia	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
YHH1_k127_10792787_2	525904.Tter_2241	8.705e-09	63.0	COG1670@1|root,COG1670@2|Bacteria,2NRB9@2323|unclassified Bacteria	2|Bacteria	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,GNAT_acetyltran
YHH1_k127_10792787_0	935837.JAEK01000008_gene3485	7.297e-23	109.0	COG2120@1|root,COG2120@2|Bacteria,1V2QU@1239|Firmicutes,4HGPT@91061|Bacilli,1ZGPD@1386|Bacillus	91061|Bacilli	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
YHH1_k127_10799779_0	1121129.KB903360_gene3644	4.602e-223	705.0	COG1042@1|root,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,2FNSJ@200643|Bacteroidia,22WFU@171551|Porphyromonadaceae	976|Bacteroidetes	C	CoA ligase	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
YHH1_k127_10799779_1	111780.Sta7437_1577	1.018e-05	56.0	COG1943@1|root,COG1943@2|Bacteria,1G79U@1117|Cyanobacteria,3VK18@52604|Pleurocapsales	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_10799779_2	204536.SULAZ_0214	7.774e-05	45.0	COG0809@1|root,COG0809@2|Bacteria,2G3KG@200783|Aquificae	200783|Aquificae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
YHH1_k127_10804284_3	1121104.AQXH01000001_gene1762	4.717e-07	55.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1IPUY@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
YHH1_k127_10804284_2	1227739.Hsw_0755	4.278e-18	96.0	COG1555@1|root,COG1555@2|Bacteria,4NQC1@976|Bacteroidetes,47Q92@768503|Cytophagia	976|Bacteroidetes	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10804284_0	945713.IALB_2238	5.89e-95	319.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
YHH1_k127_10804284_1	945713.IALB_1059	1.548e-37	151.0	2EAWV@1|root,334Y2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10828566_1	945713.IALB_0263	1.041e-31	137.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07710,ko:K10942	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
YHH1_k127_10828566_0	1157632.AQWQ01000006_gene348	7.46e-71	258.0	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,2GKK1@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3372,PUD
YHH1_k127_10829833_0	1303518.CCALI_02236	7.49e-25	110.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_10841751_2	582899.Hden_0483	1.228e-21	108.0	COG1215@1|root,COG1215@2|Bacteria,1Q6U2@1224|Proteobacteria,2VG3U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Hopanoid biosynthesis associated glycosyl transferase protein HpnI	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
YHH1_k127_10841751_0	1449976.KALB_4040	5.911e-25	121.0	COG0300@1|root,COG0300@2|Bacteria,2I64P@201174|Actinobacteria,4E2W2@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
YHH1_k127_10841751_1	671143.DAMO_0250	3.653e-22	106.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
YHH1_k127_1084342_2	518766.Rmar_2009	4.14e-10	61.0	COG1959@1|root,COG1959@2|Bacteria,4NURI@976|Bacteroidetes,1FJGW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH1_k127_1084342_0	945713.IALB_0857	1.038e-116	386.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_5
YHH1_k127_1084342_1	1191523.MROS_1097	1.38e-18	94.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp,BBP2,MucBP,Porin_4,SLH
YHH1_k127_10860450_0	945713.IALB_2978	0.0	1045.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YHH1_k127_10860450_2	323261.Noc_1255	2.093e-142	466.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales	135613|Chromatiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH1_k127_10860450_1	945713.IALB_2982	9.273e-194	614.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	lpdA	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
YHH1_k127_10867156_0	1191523.MROS_0402	6.319e-172	549.0	COG2978@1|root,COG2978@2|Bacteria	2|Bacteria	H	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity	ydaH	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
YHH1_k127_10867156_1	1254432.SCE1572_43885	1.635e-95	332.0	COG4531@1|root,COG4531@2|Bacteria,1REHQ@1224|Proteobacteria,42TZ1@68525|delta/epsilon subdivisions,2WQ6N@28221|Deltaproteobacteria,2YY91@29|Myxococcales	28221|Deltaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10867156_2	1191523.MROS_0042	2.309e-23	104.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF3341
YHH1_k127_10882678_2	1501391.LG35_06490	1.149e-33	149.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,2FQHX@200643|Bacteroidia,22UFH@171550|Rikenellaceae	976|Bacteroidetes	S	Uncharacterized protein family UPF0029	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
YHH1_k127_10882678_0	1191523.MROS_0374	3.486e-161	516.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_10882678_1	1191523.MROS_0430	2.396e-40	169.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
YHH1_k127_10898687_0	945713.IALB_0464	1.195e-71	253.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
YHH1_k127_10898687_1	589865.DaAHT2_0779	5.536e-08	64.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
YHH1_k127_10898687_2	1121896.JMLU01000002_gene352	1.517e-07	58.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1HXI1@117743|Flavobacteriia,2NUVM@237|Flavobacterium	976|Bacteroidetes	O	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
YHH1_k127_10901714_2	903818.KI912268_gene1297	8.855e-10	65.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin
YHH1_k127_10901714_1	265072.Mfla_0179	2.244e-13	70.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2VK6T@28216|Betaproteobacteria,2KP63@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
YHH1_k127_10901714_0	1121396.KB893067_gene1550	1.794e-101	334.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,42MR4@68525|delta/epsilon subdivisions,2WM3M@28221|Deltaproteobacteria,2MMW9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
YHH1_k127_10901714_4	359.CN09_08760	0.0002609	48.0	COG0642@1|root,COG2205@2|Bacteria,1RFM6@1224|Proteobacteria,2U8CN@28211|Alphaproteobacteria,4BFSD@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Protein of unknown function (DUF2809)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2809
YHH1_k127_10901714_3	797114.C475_06540	2.396e-05	53.0	COG2304@1|root,arCOG03991@1|root,arCOG09176@1|root,arCOG02902@2157|Archaea,arCOG03991@2157|Archaea,arCOG09176@2157|Archaea,2XVVH@28890|Euryarchaeota,23SGN@183963|Halobacteria	183963|Halobacteria	K	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
YHH1_k127_10907904_0	945713.IALB_1150	8.99e-102	334.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	leuD	-	4.2.1.33,4.2.1.35,4.2.1.36	ko:K01703,ko:K01704,ko:K01705	ko00290,ko00300,ko00660,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00966,map01100,map01110,map01120,map01130,map01210,map01230	M00030,M00432,M00433,M00535	R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH1_k127_10907904_1	1047013.AQSP01000140_gene2449	1.22e-44	168.0	COG1418@1|root,COG1418@2|Bacteria,2NPXI@2323|unclassified Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950,ko:K09163	-	-	-	-	ko00000	-	-	-	HD
YHH1_k127_10907904_2	1333998.M2A_2021	6.69e-15	78.0	COG1556@1|root,COG1556@2|Bacteria,1R4TE@1224|Proteobacteria,2U5II@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
YHH1_k127_1092327_1	945713.IALB_2995	2.006e-24	113.0	COG4288@1|root,COG4288@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Big_5,CHU_C,FlgD_ig,LTD
YHH1_k127_1092327_0	945713.IALB_1686	5.918e-30	123.0	2ESFM@1|root,33K0C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1092327_2	879309.HMPREF9199_0442	9.133e-24	111.0	COG2385@1|root,COG3266@1|root,COG2385@2|Bacteria,COG3266@2|Bacteria,1UW6J@1239|Firmicutes,4H227@909932|Negativicutes	909932|Negativicutes	D	SpoIID LytB domain protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
YHH1_k127_10953465_2	323259.Mhun_2690	1.345e-18	89.0	COG0784@1|root,arCOG02589@2157|Archaea,2Y08T@28890|Euryarchaeota,2N9Z9@224756|Methanomicrobia	224756|Methanomicrobia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH1_k127_10953465_0	1479237.JMLY01000001_gene2740	5.165e-133	442.0	COG1012@1|root,COG1012@2|Bacteria,1R3TA@1224|Proteobacteria,1S021@1236|Gammaproteobacteria,46AD5@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	gapN	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH1_k127_10953465_1	459349.CLOAM1530	4.744e-77	262.0	COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12,1.2.1.59,1.4.1.16	ko:K00134,ko:K00150,ko:K03340	ko00010,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00526,M00552	R01061,R01063,R02755	RC00006,RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	DapB_N,Gp_dh_C,Gp_dh_N
YHH1_k127_10978478_1	316274.Haur_1733	5.207e-99	327.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH1_k127_10978478_0	1128421.JAGA01000003_gene2922	4.228e-113	372.0	COG0479@1|root,COG0479@2|Bacteria,2NPY8@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
YHH1_k127_10978478_2	911045.PSE_p0146	2.451e-29	123.0	COG3385@1|root,COG3385@2|Bacteria,1RCTP@1224|Proteobacteria,2UPV7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH1_k127_10989494_0	945713.IALB_2185	8.026e-69	244.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria	2|Bacteria	S	Nucleoside recognition	spmB	-	-	ko:K06373,ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
YHH1_k127_10989494_1	1191523.MROS_2404	1.696e-58	218.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria	2|Bacteria	S	Nucleoside recognition	spmB	-	-	ko:K06373,ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
YHH1_k127_10989494_2	945713.IALB_1858	4.258e-36	153.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	MORN_2,Peptidase_C14,Pkinase,Sel1
YHH1_k127_1104667_0	1121430.JMLG01000012_gene1993	2.571e-36	149.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,265M1@186807|Peptococcaceae	186801|Clostridia	J	RNA 2'-O ribose methyltransferase substrate binding	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
YHH1_k127_1104667_1	521460.Athe_2120	0.0007624	51.0	COG0553@1|root,COG2304@1|root,COG5492@1|root,COG0553@2|Bacteria,COG2304@2|Bacteria,COG5492@2|Bacteria,1V09B@1239|Firmicutes,25F6N@186801|Clostridia	186801|Clostridia	M	Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,PT-TG,VWA
YHH1_k127_1114514_6	258533.BN977_02710	4.672e-21	98.0	COG1215@1|root,COG1215@2|Bacteria,2HNME@201174|Actinobacteria,2351N@1762|Mycobacteriaceae	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_1114514_3	744872.Spica_2493	9.787e-54	206.0	COG1262@1|root,COG1262@2|Bacteria,2J5Y8@203691|Spirochaetes	203691|Spirochaetes	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Flavodoxin_4
YHH1_k127_1114514_0	945713.IALB_1562	2.129e-160	522.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
YHH1_k127_1114514_4	945713.IALB_1563	7.101e-41	162.0	2ETT1@1|root,33MAE@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
YHH1_k127_1114514_2	608538.HTH_0106	1.145e-54	199.0	COG0663@1|root,COG0663@2|Bacteria,2G3ZR@200783|Aquificae	200783|Aquificae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YHH1_k127_1114514_1	357808.RoseRS_0439	2.382e-78	275.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,375H1@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
YHH1_k127_1114514_5	926569.ANT_14780	1.974e-33	139.0	COG0494@1|root,COG0494@2|Bacteria,2G7AT@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH1_k127_1114514_7	698758.AXY_18820	3.835e-14	85.0	COG2304@1|root,COG2304@2|Bacteria,1TQXZ@1239|Firmicutes,4HB0B@91061|Bacilli	91061|Bacilli	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	GATase1_like,VWA,VWA_2,VWA_3
YHH1_k127_1138042_0	945713.IALB_0609	1.154e-230	732.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	PD40,Peptidase_S9
YHH1_k127_1138042_1	1089547.KB913013_gene1276	1.656e-40	153.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,47P7N@768503|Cytophagia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
YHH1_k127_1149103_0	1191523.MROS_0518	0.0009843	52.0	COG1404@1|root,COG4677@1|root,COG1404@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,Pectate_lyase_3,fn3
YHH1_k127_1150821_2	1123278.KB893592_gene5989	8.383e-05	51.0	COG2133@1|root,COG2133@2|Bacteria,4NIJA@976|Bacteroidetes,47NB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_3,PA14
YHH1_k127_1150821_0	880073.Calab_2584	2.598e-151	481.0	COG2987@1|root,COG2987@2|Bacteria,2NP09@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_0688	Urocanase,Urocanase_C,Urocanase_N
YHH1_k127_1159273_1	1191523.MROS_2362	1.507e-89	298.0	COG0055@1|root,COG0055@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpD	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658	ATP-synt_ab,ATP-synt_ab_N
YHH1_k127_1159273_0	518766.Rmar_0286	9.117e-133	443.0	COG0366@1|root,COG0366@2|Bacteria,4PIQT@976|Bacteroidetes,1FIMY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
YHH1_k127_1165423_3	1279019.ARQK01000043_gene2168	2.682e-39	155.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1WWI0@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YHH1_k127_1165423_2	1121930.AQXG01000008_gene156	6.778e-64	227.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1IQ1X@117747|Sphingobacteriia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
YHH1_k127_1165423_1	1191523.MROS_2503	2.319e-80	276.0	COG1624@1|root,COG1624@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N,YojJ
YHH1_k127_1165423_0	644282.Deba_0763	1.646e-83	286.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
YHH1_k127_1167220_4	1191523.MROS_0434	9.72e-17	81.0	2DNWK@1|root,32ZJI@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
YHH1_k127_1167220_3	945713.IALB_1801	1.012e-24	116.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YHH1_k127_1167220_1	945713.IALB_1800	1.367e-50	203.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
YHH1_k127_1167220_2	1216932.CM240_2970	4.599e-30	136.0	COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,248TA@186801|Clostridia,36ESX@31979|Clostridiaceae	186801|Clostridia	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YHH1_k127_1167220_0	945713.IALB_2607	9.03e-77	267.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,TPR_8
YHH1_k127_1193366_6	1297742.A176_05728	7.305e-07	54.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria,2Z2QM@29|Myxococcales	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
YHH1_k127_1193366_5	945713.IALB_0884	2.808e-30	130.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_1193366_1	452637.Oter_1107	4.728e-60	220.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
YHH1_k127_1193366_4	498848.TaqDRAFT_4331	3.729e-31	138.0	COG1404@1|root,COG1404@2|Bacteria,1WJ4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
YHH1_k127_1193366_0	945713.IALB_2990	3.367e-65	240.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4397
YHH1_k127_1193366_2	945550.VISI1226_11057	1.191e-42	164.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria,1XXKV@135623|Vibrionales	135623|Vibrionales	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
YHH1_k127_1193366_3	926562.Oweho_2464	1.116e-35	145.0	COG4409@1|root,COG4409@2|Bacteria,4PBA1@976|Bacteroidetes,1ICPD@117743|Flavobacteriia,2PBHN@246874|Cryomorphaceae	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1193500_3	1122621.ATZA01000019_gene4262	4.9e-11	72.0	COG4856@1|root,COG4856@2|Bacteria,4NHJQ@976|Bacteroidetes,1IP6W@117747|Sphingobacteriia	976|Bacteroidetes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
YHH1_k127_1193500_0	401526.TcarDRAFT_0232	9.434e-195	629.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4H3GD@909932|Negativicutes	909932|Negativicutes	P	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	FeoB_C,FeoB_N,Gate
YHH1_k127_1193500_2	1191523.MROS_2653	1.942e-11	69.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
YHH1_k127_1193500_1	472759.Nhal_0882	6.145e-12	67.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1WYAR@135613|Chromatiales	135613|Chromatiales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH1_k127_120293_2	518766.Rmar_1854	3.777e-19	98.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_120293_0	1191523.MROS_2072	1.544e-45	176.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_120293_1	945713.IALB_1258	9.348e-38	151.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	MtrB_PioB
YHH1_k127_1208591_1	335543.Sfum_3709	5.078e-93	312.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WJNC@28221|Deltaproteobacteria,2MRBV@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM Anthranilate synthase component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
YHH1_k127_1208591_4	266117.Rxyl_0760	1.271e-25	118.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YHH1_k127_1208591_3	1191523.MROS_0138	8.615e-32	130.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	nuoJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YHH1_k127_1208591_2	945713.IALB_1870	9.566e-36	139.0	COG0713@1|root,COG0713@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YHH1_k127_1208591_0	1191523.MROS_0136	4.135e-147	473.0	COG1009@1|root,COG1009@2|Bacteria	2|Bacteria	CP	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
YHH1_k127_1208727_0	1121904.ARBP01000012_gene1377	3.492e-46	186.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria	1121904.ARBP01000012_gene1377|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1216929_1	262724.TT_P0048	4.043e-65	229.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
YHH1_k127_1216929_0	1499967.BAYZ01000036_gene2418	0.0	1110.0	COG0438@1|root,COG0438@2|Bacteria,2NNZH@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_1228969_0	1191523.MROS_1718	9.019e-194	631.0	COG0532@1|root,COG0532@2|Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
YHH1_k127_1228969_1	1094466.KQS_01600	1.252e-08	59.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1HY37@117743|Flavobacteriia,2NTAP@237|Flavobacterium	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
YHH1_k127_1230993_0	40571.JOEA01000032_gene699	5.965e-54	194.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4E1WD@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
YHH1_k127_1230993_1	240015.ACP_3384	3.003e-47	188.0	COG3534@1|root,COG3534@2|Bacteria,3Y7C8@57723|Acidobacteria,2JM51@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1251122_0	616991.JPOO01000001_gene2762	4.625e-83	281.0	COG2856@1|root,COG3093@1|root,COG2856@2|Bacteria,COG3093@2|Bacteria,4NHNX@976|Bacteroidetes,1I1A8@117743|Flavobacteriia	976|Bacteroidetes	K	Plasmid maintenance system antidote protein	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
YHH1_k127_1251122_1	616991.JPOO01000001_gene2761	1.502e-42	158.0	COG3549@1|root,COG3549@2|Bacteria,4NT4R@976|Bacteroidetes,1I6MK@117743|Flavobacteriia	976|Bacteroidetes	S	Plasmid maintenance system killer	-	-	-	-	-	-	-	-	-	-	-	-	HigB-like_toxin
YHH1_k127_1251122_2	443143.GM18_2660	5.78e-32	141.0	COG2378@1|root,COG2378@2|Bacteria,1PE00@1224|Proteobacteria,42T67@68525|delta/epsilon subdivisions,2X5N2@28221|Deltaproteobacteria,43SWU@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
YHH1_k127_1257125_1	1499967.BAYZ01000195_gene3106	1.398e-29	123.0	COG1807@1|root,COG1807@2|Bacteria,2NPZC@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	MA20_19960	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH1_k127_1257125_0	880073.Calab_3343	4.031e-165	526.0	COG0667@1|root,COG0667@2|Bacteria,2NQHN@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	-	GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH1_k127_1257125_2	1121405.dsmv_1980	1.235e-22	98.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42NJ1@68525|delta/epsilon subdivisions,2WJ5S@28221|Deltaproteobacteria,2MIZQ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Belongs to the methyltransferase superfamily	rlmL	-	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
YHH1_k127_1270748_0	1128421.JAGA01000003_gene2748	1.36e-45	176.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
YHH1_k127_1270748_2	1150599.MPHLEI_06922	2.885e-15	81.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,232UR@1762|Mycobacteriaceae	201174|Actinobacteria	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0008150,GO:0040007	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0553	MR_MLE_C
YHH1_k127_1270748_1	485914.Hmuk_2249	2.685e-18	87.0	COG4948@1|root,arCOG01168@2157|Archaea,2XU6X@28890|Euryarchaeota,23SAR@183963|Halobacteria	183963|Halobacteria	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
YHH1_k127_1288485_1	945713.IALB_0373	3.944e-41	156.0	COG0272@1|root,COG0272@2|Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972,ko:K10754	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	M00289,M00295	R00382	RC00005	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YHH1_k127_1288485_3	1168034.FH5T_16750	8.009e-14	76.0	COG1366@1|root,COG1366@2|Bacteria,4NTAB@976|Bacteroidetes,2FYPE@200643|Bacteroidia	976|Bacteroidetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
YHH1_k127_1288485_0	1519464.HY22_08205	1.156e-126	423.0	COG0591@1|root,COG0591@2|Bacteria,1FDKA@1090|Chlorobi	1090|Chlorobi	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH1_k127_1288485_2	1279009.ADICEAN_01390	4.341e-40	150.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,47MV2@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH1_k127_1292506_1	1123392.AQWL01000008_gene1211	7.431e-10	61.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,1KRN8@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH1_k127_1292506_0	945713.IALB_1764	3.471e-97	340.0	COG5448@1|root,COG5448@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
YHH1_k127_1295559_4	215803.DB30_7610	4.161e-14	87.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
YHH1_k127_1295559_0	1279009.ADICEAN_00447	1.27e-159	516.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,47JA3@768503|Cytophagia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
YHH1_k127_1295559_1	1237149.C900_04847	1.385e-112	374.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,47KCS@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
YHH1_k127_1295559_2	1121957.ATVL01000008_gene4201	1.212e-69	247.0	COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,47JI3@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
YHH1_k127_1295559_3	153721.MYP_1172	1.29e-17	83.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,47JPH@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YHH1_k127_1304366_0	1313301.AUGC01000003_gene2121	3.54e-56	204.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
YHH1_k127_1304366_1	945713.IALB_1563	2.868e-07	61.0	2ETT1@1|root,33MAE@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
YHH1_k127_1306296_0	1121097.JCM15093_2420	3.456e-66	237.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,2FN1C@200643|Bacteroidia,4AKTJ@815|Bacteroidaceae	976|Bacteroidetes	S	glutaminyl-peptide cyclotransferase (glutaminyl cyclase) K00683	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YHH1_k127_1306296_2	1191523.MROS_1360	2.889e-22	114.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,SLH,SprB,VCBS
YHH1_k127_1306296_3	483219.LILAB_22105	1.516e-21	111.0	COG3227@1|root,COG4733@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria,1NNV4@1224|Proteobacteria,42Q3S@68525|delta/epsilon subdivisions,2WMM2@28221|Deltaproteobacteria,2Z1Q8@29|Myxococcales	28221|Deltaproteobacteria	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1306296_1	189426.PODO_19850	2.004e-48	177.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,26QZ3@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
YHH1_k127_1333289_1	945713.IALB_0376	6.944e-65	226.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	glmU	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_4
YHH1_k127_1333289_0	945713.IALB_0375	4.475e-147	478.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria	2|Bacteria	J	transcription antitermination	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
YHH1_k127_1364900_1	1499967.BAYZ01000167_gene6758	9.39e-93	323.0	COG0249@1|root,COG0249@2|Bacteria,2NQ0S@2323|unclassified Bacteria	2|Bacteria	L	ATPase domain of DNA mismatch repair MUTS family	mutS1	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
YHH1_k127_1364900_0	506534.Rhein_3092	7.444e-193	619.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RYFT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YHH1_k127_1378336_0	575540.Isop_1073	6.412e-41	173.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,2J3AX@203682|Planctomycetes	2|Bacteria	O	COGs COG4935 Regulatory P domain of the subtilisin-like proprotein convertase and other protease	prcA	-	3.4.21.121	ko:K13735,ko:K20276,ko:K20755,ko:K21449	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	B_lectin,Calx-beta,P_proprotein,Peptidase_S8
YHH1_k127_1378336_1	84531.JMTZ01000068_gene1770	6.607e-25	121.0	COG2132@1|root,COG4935@1|root,COG2132@2|Bacteria,COG4935@2|Bacteria,1NJV7@1224|Proteobacteria,1RN7Q@1236|Gammaproteobacteria,1XAU9@135614|Xanthomonadales	135614|Xanthomonadales	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_4
YHH1_k127_1378336_4	1191523.MROS_2841	1.758e-18	100.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
YHH1_k127_1378336_2	404380.Gbem_1400	1.367e-20	104.0	COG4393@1|root,COG4393@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2318)	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF2318
YHH1_k127_1378336_5	1392488.JHZY01000002_gene1018	0.0002112	52.0	2EG6J@1|root,339YE@2|Bacteria,4NYAK@976|Bacteroidetes,1I72X@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1378336_3	1123008.KB905708_gene1009	7.973e-19	100.0	COG0845@1|root,COG2608@1|root,COG0845@2|Bacteria,COG2608@2|Bacteria,4NG8S@976|Bacteroidetes,2FMQN@200643|Bacteroidia,22X6K@171551|Porphyromonadaceae	976|Bacteroidetes	MP	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HMA,HlyD_D23
YHH1_k127_1378947_0	945713.IALB_0341	1.573e-302	938.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH1_k127_1412183_0	945713.IALB_2203	1.023e-191	609.0	COG0773@1|root,COG0773@2|Bacteria	2|Bacteria	M	UDP-N-acetylmuramate-L-alanine ligase activity	murC	GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iECP_1309.ECP_0093,iJN678.murC	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_1412183_2	1410632.JHWW01000001_gene998	5.083e-72	253.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,27J9M@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
YHH1_k127_1412183_3	349161.Dred_0679	5.701e-08	63.0	COG1589@1|root,COG1589@2|Bacteria,1VEMW@1239|Firmicutes,24QKM@186801|Clostridia,26202@186807|Peptococcaceae	186801|Clostridia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
YHH1_k127_1412183_1	518766.Rmar_2698	6.295e-158	508.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1FJ0Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
YHH1_k127_1412577_0	1121904.ARBP01000003_gene6255	2.601e-97	328.0	COG4206@1|root,COG4206@2|Bacteria,4PKFW@976|Bacteroidetes,47Y2Y@768503|Cytophagia	976|Bacteroidetes	H	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
YHH1_k127_1412577_1	290317.Cpha266_2156	4.513e-49	177.0	COG2606@1|root,COG2606@2|Bacteria,1FF1M@1090|Chlorobi	1090|Chlorobi	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
YHH1_k127_1446362_0	1250005.PHEL85_3394	1.108e-45	189.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HX4T@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
YHH1_k127_1483912_0	926562.Oweho_1489	2.08e-209	666.0	COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,1I7PU@117743|Flavobacteriia	976|Bacteroidetes	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
YHH1_k127_1483912_1	1227739.Hsw_0986	1.144e-10	71.0	COG2831@1|root,COG2931@1|root,COG2831@2|Bacteria,COG2931@2|Bacteria,4PPJE@976|Bacteroidetes,47YRQ@768503|Cytophagia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH1_k127_1485543_0	945713.IALB_1830	1.874e-07	63.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,CBM_3,Cellulase,Glug,Glyco_hydro_9,MAM,PKD,fn3
YHH1_k127_1485543_1	411477.PARMER_03406	0.000958	45.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,2FMIV@200643|Bacteroidia,22WVT@171551|Porphyromonadaceae	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
YHH1_k127_1489631_2	338963.Pcar_1971	3.621e-40	164.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,43S1Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	HK	HTH domain	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
YHH1_k127_1489631_0	1303518.CCALI_00980	1.729e-88	306.0	COG1104@1|root,COG1104@2|Bacteria	2|Bacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YHH1_k127_1489631_1	290512.Paes_2180	1.594e-54	204.0	COG0248@1|root,COG0248@2|Bacteria,1FDV8@1090|Chlorobi	1090|Chlorobi	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
YHH1_k127_1489631_3	377629.TERTU_3081	2.354e-08	57.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,2PN4Y@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	prmA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
YHH1_k127_1502725_3	762903.Pedsa_1501	6.624e-13	74.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
YHH1_k127_1502725_2	945713.IALB_0654	1.936e-44	169.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Hydrolase_3,Pro_isomerase
YHH1_k127_1502725_1	517418.Ctha_0740	8.406e-96	320.0	COG1968@1|root,COG1968@2|Bacteria,1FDGJ@1090|Chlorobi	1090|Chlorobi	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
YHH1_k127_1502725_0	1519464.HY22_06495	5.926e-202	647.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,1FEG8@1090|Chlorobi	1090|Chlorobi	E	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA,GFO_IDH_MocA_C
YHH1_k127_1529802_0	1408813.AYMG01000032_gene5239	1.092e-45	182.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IR0W@117747|Sphingobacteriia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,SASA,SprB
YHH1_k127_1529802_1	411461.DORFOR_01303	5.545e-06	57.0	COG2304@1|root,COG2304@2|Bacteria,1VAM7@1239|Firmicutes,24NRP@186801|Clostridia,27WHS@189330|Dorea	186801|Clostridia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,zinc_ribbon_2
YHH1_k127_1534670_1	543728.Vapar_5756	3.978e-90	303.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,2VHF9@28216|Betaproteobacteria,4ADRK@80864|Comamonadaceae	28216|Betaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
YHH1_k127_1534670_2	994573.T472_0215345	2.136e-41	158.0	COG3324@1|root,COG3324@2|Bacteria,1V48C@1239|Firmicutes	1239|Firmicutes	S	glyoxalase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YHH1_k127_1534670_0	1121939.L861_17285	7.224e-233	727.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,1RRDD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
YHH1_k127_1534670_3	1196322.A370_03907	2.607e-39	153.0	COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,24K4J@186801|Clostridia,36JND@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
YHH1_k127_1534670_4	1242864.D187_003973	1.341e-28	116.0	COG0346@1|root,COG0346@2|Bacteria,1RIAM@1224|Proteobacteria,43827@68525|delta/epsilon subdivisions,2X3CD@28221|Deltaproteobacteria,2YVE1@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YHH1_k127_1534670_6	1254432.SCE1572_39360	2.521e-08	56.0	COG0346@1|root,COG0346@2|Bacteria,1RIAM@1224|Proteobacteria,43827@68525|delta/epsilon subdivisions,2X3CD@28221|Deltaproteobacteria,2YVE1@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YHH1_k127_1556051_0	945713.IALB_0487	2.096e-232	741.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	ebh	-	-	-	-	-	-	-	-	-	-	-	DUF1611,Inhibitor_I9,Peptidase_S8,SLH
YHH1_k127_1563552_0	391596.PBAL39_09886	2.318e-257	802.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YHH1_k127_1563552_1	517418.Ctha_1617	5.552e-40	151.0	COG0234@1|root,COG0234@2|Bacteria,1FE2T@1090|Chlorobi	1090|Chlorobi	J	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YHH1_k127_1563552_2	1191523.MROS_2591	7.65e-24	108.0	COG1564@1|root,COG1564@2|Bacteria	2|Bacteria	H	THIamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
YHH1_k127_1563904_1	580332.Slit_1776	1.329e-57	216.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	Bac_surface_Ag
YHH1_k127_1563904_0	580332.Slit_1219	8.017e-72	244.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VNB4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA1	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
YHH1_k127_1606456_3	1121382.JQKG01000078_gene1356	1.096e-30	128.0	COG0791@1|root,COG0791@2|Bacteria,1WJI4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Cell wall-associated hydrolase (invasion-associated protein)	-	-	-	-	-	-	-	-	-	-	-	-	LysM,NLPC_P60
YHH1_k127_1606456_2	1121930.AQXG01000005_gene671	3.253e-44	175.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
YHH1_k127_1606456_1	945713.IALB_0319	3.246e-50	187.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	CP_0228	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
YHH1_k127_1606456_0	1191523.MROS_0746	8.332e-133	434.0	COG0608@1|root,COG0608@2|Bacteria	2|Bacteria	L	single-stranded DNA 5'-3' exodeoxyribonuclease activity	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH1_k127_1612378_1	1499967.BAYZ01000104_gene3707	1.665e-81	277.0	COG1875@1|root,COG1875@2|Bacteria,2NP4K@2323|unclassified Bacteria	2|Bacteria	T	PIN domain	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
YHH1_k127_1612378_2	290318.Cvib_1106	2.073e-59	212.0	COG2131@1|root,COG2131@2|Bacteria,1FDBV@1090|Chlorobi	1090|Chlorobi	F	PFAM CMP dCMP deaminase zinc-binding	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
YHH1_k127_1612378_0	1123248.KB893319_gene4061	8.35e-90	309.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
YHH1_k127_1626367_0	1183438.GKIL_3356	4.68e-160	527.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
YHH1_k127_1626367_1	1303518.CCALI_01862	1.413e-99	350.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278,ko:K06889	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	PD40,Peptidase_S9
YHH1_k127_1626367_2	518766.Rmar_0047	4.352e-14	74.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1FJ3A@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH1_k127_1627961_1	546271.Selsp_0468	1.278e-14	83.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H445@909932|Negativicutes	909932|Negativicutes	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
YHH1_k127_1627961_0	945713.IALB_2170	1.636e-178	571.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	putP	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH1_k127_1634898_1	945713.IALB_2638	7.136e-147	477.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH1_k127_1634898_2	1122921.KB898186_gene5162	1.72e-21	106.0	COG1105@1|root,COG1105@2|Bacteria,1TR9H@1239|Firmicutes,4HAGR@91061|Bacilli,274KT@186822|Paenibacillaceae	91061|Bacilli	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	lacC	-	2.7.1.144	ko:K00917	ko00052,ko01100,map00052,map01100	-	R03236	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH1_k127_1634898_0	880073.Calab_0665	2.435e-263	830.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2NNT2@2323|unclassified Bacteria	2|Bacteria	C	Transketolase, pyrimidine binding domain	CP_0743	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
YHH1_k127_1651455_5	1284352.AOIG01000022_gene3754	8.125e-05	51.0	COG1427@1|root,COG1427@2|Bacteria,1V2PX@1239|Firmicutes,4HFX0@91061|Bacilli,26T7N@186822|Paenibacillaceae	91061|Bacilli	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
YHH1_k127_1651455_2	443218.AS9A_1571	5.102e-39	148.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,239BS@1762|Mycobacteriaceae	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
YHH1_k127_1651455_1	1121104.AQXH01000004_gene32	2.558e-86	292.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,1IQ54@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
YHH1_k127_1651455_4	1121296.JONJ01000002_gene1345	1.64e-30	126.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,220BW@1506553|Lachnoclostridium	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
YHH1_k127_1651455_3	1191523.MROS_0269	6.976e-31	131.0	COG0228@1|root,COG0228@2|Bacteria	2|Bacteria	J	mitochondrial translation	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
YHH1_k127_1651455_0	945713.IALB_0774	2.581e-163	525.0	COG0541@1|root,COG0541@2|Bacteria	2|Bacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
YHH1_k127_1657080_2	945713.IALB_0728	1.062e-59	216.0	COG2366@1|root,COG2366@2|Bacteria	2|Bacteria	D	antibiotic biosynthetic process	acyII	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
YHH1_k127_1657080_0	313606.M23134_02806	1.922e-154	507.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
YHH1_k127_1657080_1	330214.NIDE3218	9.302e-66	234.0	COG0388@1|root,COG0388@2|Bacteria,3J11H@40117|Nitrospirae	40117|Nitrospirae	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
YHH1_k127_1657080_4	1191523.MROS_1837	1.207e-44	169.0	COG2121@1|root,COG2121@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF374)	MA20_05800	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K09778	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	DUF374
YHH1_k127_1657080_3	319225.Plut_1655	1.229e-55	207.0	COG1663@1|root,COG1663@2|Bacteria,1FDUF@1090|Chlorobi	1090|Chlorobi	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
YHH1_k127_1695894_0	945713.IALB_0608	1.102e-90	309.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
YHH1_k127_1695894_1	945713.IALB_2863	3.989e-32	132.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	CARDB,FTP,He_PIG,PA,Peptidase_M30,Peptidase_M36,Peptidase_M6
YHH1_k127_1700260_4	886293.Sinac_4502	1.504e-06	53.0	COG0122@1|root,COG0122@2|Bacteria,2J0B5@203682|Planctomycetes	203682|Planctomycetes	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
YHH1_k127_1700260_3	1519464.HY22_13590	3.936e-14	75.0	2BVK8@1|root,32Y0S@2|Bacteria,1FFKG@1090|Chlorobi	1090|Chlorobi	S	histone H1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1700260_0	1385515.N791_02135	2.242e-84	292.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1X32H@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
YHH1_k127_1700260_2	338963.Pcar_3030	2.611e-69	241.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,42MF3@68525|delta/epsilon subdivisions,2WJXS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM class II aldolase adducin family protein	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
YHH1_k127_1700260_1	96561.Dole_0407	5.27e-80	274.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria,2MI60@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
YHH1_k127_1702580_2	304371.MCP_0027	3.07e-45	175.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
YHH1_k127_1702580_3	391625.PPSIR1_29870	8.313e-16	82.0	COG1393@1|root,COG1393@2|Bacteria,1Q3YZ@1224|Proteobacteria,42XF4@68525|delta/epsilon subdivisions,2WSMU@28221|Deltaproteobacteria,2Z342@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
YHH1_k127_1702580_1	313628.LNTAR_10466	6.887e-72	252.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
YHH1_k127_1702580_0	1163617.SCD_n00754	4.181e-80	294.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,2VHCH@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YHH1_k127_1709512_4	63737.Npun_R5596	1.818e-73	259.0	COG1253@1|root,COG1253@2|Bacteria,1G2HK@1117|Cyanobacteria,1HIJB@1161|Nostocales	1117|Cyanobacteria	S	PFAM CBS domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
YHH1_k127_1709512_0	1191523.MROS_2410	1.159e-214	679.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	porX	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	PglZ,Response_reg
YHH1_k127_1709512_9	1379698.RBG1_1C00001G1546	9.635e-26	118.0	COG0802@1|root,COG0802@2|Bacteria,2NPU4@2323|unclassified Bacteria	2|Bacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	TsaE
YHH1_k127_1709512_8	796942.HMPREF9623_01643	3.732e-27	120.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
YHH1_k127_1709512_1	1191523.MROS_2414	1.343e-108	359.0	COG0777@1|root,COG0777@2|Bacteria	2|Bacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601	Carboxyl_trans
YHH1_k127_1709512_2	264732.Moth_0141	2.097e-88	300.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,42F66@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
YHH1_k127_1709512_7	1499683.CCFF01000016_gene744	1.889e-39	149.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,36K0M@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
YHH1_k127_1709512_6	1232428.CAVO010000138_gene104	4.078e-63	228.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H30V@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
YHH1_k127_1709512_5	118163.Ple7327_2013	7.712e-71	245.0	COG0009@1|root,COG0009@2|Bacteria,1G1KB@1117|Cyanobacteria,3VHSI@52604|Pleurocapsales	1117|Cyanobacteria	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
YHH1_k127_1709512_3	926550.CLDAP_31450	1.64e-85	295.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G5Y5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
YHH1_k127_1711946_0	945713.IALB_2136	3.294e-93	319.0	COG1570@1|root,COG1570@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseA	-	3.1.11.6,3.4.21.102	ko:K03601,ko:K03797	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
YHH1_k127_1711946_2	644282.Deba_1929	3.319e-08	61.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
YHH1_k127_1711946_1	1287276.X752_11795	1.626e-71	246.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,43GQR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	HI	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
YHH1_k127_1719226_0	945713.IALB_1647	3.519e-63	220.0	28KE7@1|root,2ZA0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1719226_1	1453500.AT05_09360	6.942e-43	179.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Exo_endo_phos,LTD
YHH1_k127_1725955_0	880073.Calab_1441	3.156e-41	167.0	COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria	2|Bacteria	S	Por secretion system C-terminal sorting domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Sortilin-Vps10
YHH1_k127_1725955_1	1125863.JAFN01000001_gene393	1.242e-31	132.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2WP66@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
YHH1_k127_1729283_0	517418.Ctha_1790	1.011e-177	566.0	COG0677@1|root,COG0677@2|Bacteria,1FEH1@1090|Chlorobi	1090|Chlorobi	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH1_k127_1729283_1	880073.Calab_0614	1.503e-145	468.0	COG0381@1|root,COG0381@2|Bacteria,2NNVT@2323|unclassified Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
YHH1_k127_1731989_0	379066.GAU_0803	3.539e-194	625.0	COG2091@1|root,COG2091@2|Bacteria,1ZUQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1762171_2	525373.HMPREF0766_10941	1.422e-29	123.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,1ISSC@117747|Sphingobacteriia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
YHH1_k127_1762171_0	945713.IALB_1891	1.518e-103	346.0	COG1137@1|root,COG1137@2|Bacteria	2|Bacteria	S	lipopolysaccharide-transporting ATPase activity	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
YHH1_k127_1762171_1	1191523.MROS_1455	1.451e-67	239.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
YHH1_k127_1762171_3	638303.Thal_1239	2.99e-08	60.0	COG1355@1|root,COG1355@2|Bacteria	2|Bacteria	C	regulation of microtubule-based process	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
YHH1_k127_1778316_7	717231.Flexsi_1814	3.857e-10	62.0	COG3808@1|root,COG3808@2|Bacteria,2GFAJ@200930|Deferribacteres	200930|Deferribacteres	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
YHH1_k127_1778316_4	697281.Mahau_0796	2.316e-41	160.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,42GBC@68295|Thermoanaerobacterales	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
YHH1_k127_1778316_3	945713.IALB_0590	5.408e-49	184.0	COG1825@1|root,COG1825@2|Bacteria	2|Bacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
YHH1_k127_1778316_0	518766.Rmar_2416	1.107e-116	384.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1FIZ1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
YHH1_k127_1778316_2	1499967.BAYZ01000167_gene6734	4.335e-55	207.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
YHH1_k127_1778316_1	945713.IALB_1892	7.85e-57	214.0	COG1452@1|root,COG1934@1|root,COG1452@2|Bacteria,COG1934@2|Bacteria	2|Bacteria	S	lipopolysaccharide binding	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_2
YHH1_k127_1778316_6	945713.IALB_1498	6.958e-30	126.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC1	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
YHH1_k127_1778316_5	1408813.AYMG01000030_gene693	7.668e-31	131.0	2AX7X@1|root,31P6Q@2|Bacteria,4NGGX@976|Bacteroidetes,1IURY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1797537_1	1191523.MROS_0286	1.812e-41	158.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug
YHH1_k127_1797537_0	177437.HRM2_21730	6.452e-67	234.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria,2MIM6@213118|Desulfobacterales	28221|Deltaproteobacteria	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
YHH1_k127_1801606_0	331678.Cphamn1_1195	1.564e-204	654.0	COG0326@1|root,COG0326@2|Bacteria,1FDQH@1090|Chlorobi	1090|Chlorobi	F	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
YHH1_k127_1801606_3	1121930.AQXG01000004_gene2828	7.165e-13	81.0	COG2911@1|root,COG2911@2|Bacteria,4PPNA@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1801606_1	933262.AXAM01000021_gene479	1.783e-21	108.0	COG1075@1|root,COG1404@1|root,COG2304@1|root,COG3507@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,COG2304@2|Bacteria,COG3507@2|Bacteria,1NDGA@1224|Proteobacteria,43DCN@68525|delta/epsilon subdivisions,2WRRD@28221|Deltaproteobacteria,2MME4@213118|Desulfobacterales	28221|Deltaproteobacteria	G	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
YHH1_k127_1801606_2	797114.C475_06540	4.954e-15	84.0	COG2304@1|root,arCOG03991@1|root,arCOG09176@1|root,arCOG02902@2157|Archaea,arCOG03991@2157|Archaea,arCOG09176@2157|Archaea,2XVVH@28890|Euryarchaeota,23SGN@183963|Halobacteria	183963|Halobacteria	K	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
YHH1_k127_1832272_3	756499.Desde_0423	4.076e-39	149.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,2620M@186807|Peptococcaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
YHH1_k127_1832272_0	96561.Dole_0708	1.759e-63	224.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,2MJKX@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
YHH1_k127_1832272_1	1304284.L21TH_0893	1.554e-58	209.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,36DFP@31979|Clostridiaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YHH1_k127_1832272_4	644282.Deba_2936	1.26e-24	106.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
YHH1_k127_1832272_2	748449.Halha_0192	1.665e-47	171.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WACR@53433|Halanaerobiales	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YHH1_k127_184189_1	1519464.HY22_00980	8.261e-87	302.0	COG0770@1|root,COG0770@2|Bacteria,1FDKX@1090|Chlorobi	1090|Chlorobi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_184189_0	945713.IALB_2209	1.187e-160	515.0	COG0472@1|root,COG0472@2|Bacteria	2|Bacteria	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
YHH1_k127_184189_2	518766.Rmar_2703	2.993e-43	166.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1FITH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH1_k127_1859608_0	1121422.AUMW01000024_gene240	2.607e-21	100.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_1859608_1	1499967.BAYZ01000050_gene2839	2.357e-05	51.0	COG0640@1|root,COG0640@2|Bacteria,2NQ13@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	3.6.4.12	ko:K03655,ko:K03892	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	HTH_20,HTH_5
YHH1_k127_1873035_0	1185876.BN8_05986	1.055e-72	254.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,47K49@768503|Cytophagia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
YHH1_k127_188087_1	204669.Acid345_1820	2.783e-94	314.0	COG0549@1|root,COG0549@2|Bacteria,3Y7CP@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YHH1_k127_188087_0	204669.Acid345_1819	1.363e-129	422.0	COG0078@1|root,COG0078@2|Bacteria,3Y4R3@57723|Acidobacteria,2JP1M@204432|Acidobacteriia	204432|Acidobacteriia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YHH1_k127_188087_2	1150474.JQJI01000034_gene1409	1.238e-42	162.0	28JAU@1|root,32XQP@2|Bacteria,2GEIC@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_188087_3	42256.RradSPS_1688	2.876e-09	69.0	COG1807@1|root,COG1807@2|Bacteria,2GNPY@201174|Actinobacteria	201174|Actinobacteria	M	capsule polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1906353_0	945713.IALB_0396	1.347e-134	444.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	crtD	-	1.3.99.26,1.3.99.27,1.3.99.28,1.3.99.29,1.3.99.31,5.4.99.9	ko:K01854,ko:K09845,ko:K10027	ko00052,ko00520,ko00906,ko01100,ko01110,map00052,map00520,map00906,map01100,map01110	-	R00505,R04787,R04798,R04800,R07517,R07520,R07523,R07534,R09009,R09691,R09692	RC00317,RC01214,RC02080,RC02088,RC02396,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
YHH1_k127_1906353_3	1370125.AUWT01000029_gene712	1.46e-17	91.0	COG2324@1|root,COG2324@2|Bacteria,2IIUJ@201174|Actinobacteria,23F1V@1762|Mycobacteriaceae	201174|Actinobacteria	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
YHH1_k127_1906353_1	1121104.AQXH01000001_gene833	1.929e-82	298.0	COG1233@1|root,COG1233@2|Bacteria,4NHU6@976|Bacteroidetes	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_1
YHH1_k127_1906353_2	926550.CLDAP_20450	5.1e-62	224.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glycos_transf_2
YHH1_k127_190832_1	518766.Rmar_2487	3.386e-55	203.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1FJ65@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
YHH1_k127_190832_0	1123060.JONP01000004_gene748	1.886e-88	322.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2TRY7@28211|Alphaproteobacteria,2JPFA@204441|Rhodospirillales	204441|Rhodospirillales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
YHH1_k127_1930971_1	1435356.Y013_04490	1.178e-49	189.0	COG1408@1|root,COG1408@2|Bacteria,2GMST@201174|Actinobacteria,4FXQI@85025|Nocardiaceae	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
YHH1_k127_1930971_0	518766.Rmar_0733	3.147e-77	289.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1FJ03@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YHH1_k127_1938657_0	926550.CLDAP_31400	2.467e-39	169.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_15,AAA_23,Rad50_zn_hook,SbcCD_C
YHH1_k127_1938657_1	931626.Awo_c34800	2.652e-32	132.0	COG0317@1|root,COG0317@2|Bacteria,1VC5K@1239|Firmicutes,24NB3@186801|Clostridia,25X95@186806|Eubacteriaceae	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
YHH1_k127_1939213_2	945713.IALB_1436	3.807e-57	204.0	COG0290@1|root,COG0290@2|Bacteria	2|Bacteria	J	translation initiation factor activity	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
YHH1_k127_1939213_5	269798.CHU_1644a	1.052e-17	84.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,47RYG@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
YHH1_k127_1939213_4	945713.IALB_1438	4.228e-38	145.0	COG0292@1|root,COG0292@2|Bacteria	2|Bacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
YHH1_k127_1939213_1	945713.IALB_1439	6.113e-129	420.0	COG0016@1|root,COG0016@2|Bacteria	2|Bacteria	J	phenylalanine-tRNA ligase activity	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YHH1_k127_1939213_0	309807.SRU_2807	5.596e-177	585.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1FIKR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Ferredoxin-fold anticodon binding domain	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
YHH1_k127_1939213_6	1379698.RBG1_1C00001G1122	5.027e-09	61.0	COG3027@1|root,COG3027@2|Bacteria,2NQ5R@2323|unclassified Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
YHH1_k127_1939213_3	1191523.MROS_0063	4.808e-43	165.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
YHH1_k127_1966419_0	1406840.Q763_00875	8.72e-77	272.0	28M4A@1|root,2ZAI8@2|Bacteria,4NIAH@976|Bacteroidetes,1I0GD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1966419_1	1122613.ATUP01000001_gene1637	1.407e-06	53.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2U0JP@28211|Alphaproteobacteria,440XX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
YHH1_k127_1976658_0	517418.Ctha_2087	2.723e-98	336.0	COG1887@1|root,COG1887@2|Bacteria,1FDQ2@1090|Chlorobi	1090|Chlorobi	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1976658_2	1519464.HY22_10770	4.379e-37	153.0	COG0392@1|root,COG0392@2|Bacteria,1FDR1@1090|Chlorobi	1090|Chlorobi	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
YHH1_k127_1976658_1	278957.ABEA03000182_gene1971	1.539e-69	240.0	COG0483@1|root,COG0483@2|Bacteria,46V41@74201|Verrucomicrobia,3K741@414999|Opitutae	414999|Opitutae	G	Inositol monophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
YHH1_k127_1980508_1	880073.Calab_3729	1.643e-117	385.0	COG0343@1|root,COG0343@2|Bacteria,2NNQS@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
YHH1_k127_1980508_2	945713.IALB_2106	7.266e-35	136.0	COG1862@1|root,COG1862@2|Bacteria	2|Bacteria	U	protein transport	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
YHH1_k127_1980508_0	945713.IALB_2105	2.18e-169	540.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria	2|Bacteria	H	GTP cyclohydrolase II activity	ribBA	-	3.5.4.25,4.1.99.12	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
YHH1_k127_1980508_3	945713.IALB_2407	9.795e-21	94.0	COG0782@1|root,COG0782@2|Bacteria	2|Bacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
YHH1_k127_1981482_1	349163.Acry_1700	2.377e-167	546.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,2JQ1S@204441|Rhodospirillales	204441|Rhodospirillales	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
YHH1_k127_1981482_2	1191523.MROS_1959	1.163e-27	121.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH1_k127_1981482_0	945713.IALB_0610	3.281e-190	602.0	COG0621@1|root,COG0621@2|Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YHH1_k127_1981482_3	945713.IALB_0611	1.279e-22	106.0	COG1729@1|root,COG3147@1|root,COG1729@2|Bacteria,COG3147@2|Bacteria	2|Bacteria	S	peptidoglycan binding	-	-	3.1.26.12	ko:K03749,ko:K07114,ko:K08300,ko:K09859	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03009,ko03019	1.A.13.2.2,1.A.13.2.3	-	-	DUF3108,Rib,SPOR,TPR_6
YHH1_k127_1981482_4	453591.Igni_1037	9.201e-12	76.0	COG1234@1|root,arCOG00501@2157|Archaea,2XQC0@28889|Crenarchaeota	28889|Crenarchaeota	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
YHH1_k127_1983621_1	1242864.D187_007369	3.652e-70	252.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,42R2C@68525|delta/epsilon subdivisions,2WMZ7@28221|Deltaproteobacteria,2YV1V@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
YHH1_k127_1983621_0	1121406.JAEX01000002_gene1126	1.01e-163	528.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria,2M9BR@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
YHH1_k127_1983621_4	794903.OPIT5_20655	2.505e-17	86.0	2A49W@1|root,30SVD@2|Bacteria,46YGH@74201|Verrucomicrobia,3K9IQ@414999|Opitutae	414999|Opitutae	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH1_k127_1983621_2	794903.OPIT5_24075	7.675e-57	198.0	COG1215@1|root,COG1215@2|Bacteria,46SRA@74201|Verrucomicrobia,3K7C7@414999|Opitutae	414999|Opitutae	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_1984103_0	1191523.MROS_2443	1.33e-46	172.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_1984103_1	945713.IALB_2264	1.009e-37	150.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_1986161_0	5786.XP_003287457.1	5.555e-243	761.0	COG3404@1|root,2QQBY@2759|Eukaryota,3XAEC@554915|Amoebozoa	554915|Amoebozoa	H	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
YHH1_k127_1986161_3	1041159.AZUW01000017_gene2186	6.325e-22	100.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U745@28211|Alphaproteobacteria,4BFWW@82115|Rhizobiaceae	28211|Alphaproteobacteria	KT	cheY-homologous receiver domain	divK	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
YHH1_k127_1986161_2	102125.Xen7305DRAFT_00016270	1.807e-36	145.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,3VNN4@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
YHH1_k127_1986161_1	880073.Calab_2582	1.028e-178	567.0	COG2309@1|root,COG2309@2|Bacteria,2NPEI@2323|unclassified Bacteria	2|Bacteria	E	Thermophilic metalloprotease (M29)	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
YHH1_k127_1986161_4	402777.KB235903_gene2254	1.515e-06	57.0	COG1943@1|root,COG1943@2|Bacteria,1G79U@1117|Cyanobacteria,1HBVQ@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_1987154_0	1168067.JAGP01000001_gene2170	1.1e-95	321.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,460S1@72273|Thiotrichales	72273|Thiotrichales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
YHH1_k127_1987154_1	1172180.KB911775_gene6056	5.649e-12	73.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
YHH1_k127_1987154_2	613026.HRAG_02410	8.747e-09	64.0	COG2849@1|root,COG2849@2|Bacteria,1MZCG@1224|Proteobacteria,42XCP@68525|delta/epsilon subdivisions,2YQ7V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
YHH1_k127_2001743_2	237368.SCABRO_01858	1.895e-41	155.0	COG1225@1|root,COG1225@2|Bacteria,2IYHT@203682|Planctomycetes	203682|Planctomycetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH1_k127_2001743_0	316067.Geob_3194	1.916e-122	397.0	COG3409@1|root,COG3409@2|Bacteria,1QYWY@1224|Proteobacteria	1224|Proteobacteria	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,PG_binding_1
YHH1_k127_2001743_1	1163409.UUA_13987	2.596e-57	204.0	COG1075@1|root,COG1075@2|Bacteria,1MXMP@1224|Proteobacteria,1RYZM@1236|Gammaproteobacteria,1X44F@135614|Xanthomonadales	135614|Xanthomonadales	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
YHH1_k127_2002987_0	945713.IALB_0362	4.908e-153	498.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	msbA	-	-	ko:K02021,ko:K06147,ko:K06148,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH1_k127_2002987_1	401526.TcarDRAFT_2737	6.386e-24	116.0	COG3307@1|root,COG3307@2|Bacteria,1V4DY@1239|Firmicutes,4H4E3@909932|Negativicutes	909932|Negativicutes	M	O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH1_k127_2022948_0	1122176.KB903559_gene4117	1.686e-83	293.0	COG1572@1|root,COG4675@1|root,COG4935@1|root,COG1572@2|Bacteria,COG4675@2|Bacteria,COG4935@2|Bacteria,4NGW4@976|Bacteroidetes,1J10S@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
YHH1_k127_2032390_1	1229276.DI53_2146	9.122e-32	126.0	COG1629@1|root,COG4771@2|Bacteria,4NFAM@976|Bacteroidetes,1IRHD@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_2032390_0	517418.Ctha_1282	2.634e-107	359.0	COG4247@1|root,COG4247@2|Bacteria,1FEBY@1090|Chlorobi	1090|Chlorobi	I	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)	-	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
YHH1_k127_2035151_1	1274374.CBLK010000070_gene1425	3.648e-35	142.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,26QB9@186822|Paenibacillaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
YHH1_k127_2035151_2	331678.Cphamn1_0004	3.386e-08	61.0	COG5512@1|root,COG5512@2|Bacteria,1FE6R@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
YHH1_k127_2035151_0	518766.Rmar_2760	2.717e-87	298.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1FIQB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
YHH1_k127_2039034_0	696369.KI912183_gene1715	1.073e-130	436.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,260X6@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_2040800_0	518766.Rmar_1003	4.871e-08	66.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	AbfB,DUF2804,DUF4981,Glyco_hydro_106,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH1_k127_2053119_1	945713.IALB_3083	6.858e-76	263.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccmC	GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
YHH1_k127_2053119_2	1191523.MROS_0624	3.636e-29	122.0	COG2332@1|root,COG2332@2|Bacteria	2|Bacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
YHH1_k127_2053119_0	1191523.MROS_0623	1.047e-102	351.0	COG1138@1|root,COG1138@2|Bacteria	2|Bacteria	O	Cytochrome C-type biogenesis protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
YHH1_k127_2056136_0	1123274.KB899406_gene1132	1.615e-47	181.0	COG0845@1|root,COG0845@2|Bacteria,2JAXG@203691|Spirochaetes	203691|Spirochaetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
YHH1_k127_2056136_1	880073.Calab_1307	5.37e-19	98.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH1_k127_2065113_2	880073.Calab_3451	4.739e-06	52.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane
YHH1_k127_2065113_0	1243664.CAVL020000025_gene1254	3.151e-76	276.0	COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,1ZCMT@1386|Bacillus	91061|Bacilli	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
YHH1_k127_2065113_1	660470.Theba_2506	9.877e-27	121.0	COG2366@1|root,COG2366@2|Bacteria	2|Bacteria	D	antibiotic biosynthetic process	pac	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
YHH1_k127_2069931_2	997829.HMPREF1121_00254	1.229e-06	52.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,2FN5J@200643|Bacteroidia,22Y0N@171551|Porphyromonadaceae	976|Bacteroidetes	F	Hypoxanthine phosphoribosyltransferase	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
YHH1_k127_2069931_0	671143.DAMO_1566	1.355e-58	222.0	COG0037@1|root,COG0037@2|Bacteria,2NPAZ@2323|unclassified Bacteria	2|Bacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,Pribosyltran,TilS,TilS_C
YHH1_k127_2069931_1	771875.Ferpe_1782	2.906e-10	70.0	COG0296@1|root,COG4945@1|root,COG0296@2|Bacteria,COG4945@2|Bacteria,2GC51@200918|Thermotogae	200918|Thermotogae	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Glucodextran_C,Glyco_hydro_57
YHH1_k127_2069931_3	246969.TAM4_432	1.68e-05	55.0	COG4945@1|root,arCOG08609@1|root,arCOG03771@2157|Archaea,arCOG08609@2157|Archaea,2XSTV@28890|Euryarchaeota,242PG@183968|Thermococci	183968|Thermococci	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glucodextran_C,Glyco_hydro_57
YHH1_k127_2077747_1	760192.Halhy_1878	2.58e-17	84.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase,Esterase_phd
YHH1_k127_2077747_2	313606.M23134_00633	1.326e-15	88.0	28MS7@1|root,2ZB0M@2|Bacteria,4NHCQ@976|Bacteroidetes,47JQ9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2077747_0	765911.Thivi_2617	2.195e-49	183.0	COG4974@1|root,COG4974@2|Bacteria,1MZES@1224|Proteobacteria,1S9MN@1236|Gammaproteobacteria,1X0YU@135613|Chromatiales	135613|Chromatiales	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
YHH1_k127_2087343_4	1519464.HY22_03200	1.37e-23	104.0	COG3536@1|root,COG3536@2|Bacteria,1FFH2@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
YHH1_k127_2087343_5	7739.XP_002590720.1	6.684e-10	64.0	2CZEB@1|root,2S9YW@2759|Eukaryota,3AB3P@33154|Opisthokonta,3BUXI@33208|Metazoa,3DB54@33213|Bilateria	33208|Metazoa	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YHH1_k127_2087343_1	518766.Rmar_1956	2.493e-96	322.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1FJ5V@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
YHH1_k127_2087343_2	517418.Ctha_0356	6.729e-52	194.0	COG0095@1|root,COG0095@2|Bacteria,1FDZ6@1090|Chlorobi	1090|Chlorobi	H	PFAM biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YHH1_k127_2087343_3	1191523.MROS_0146	8.366e-51	190.0	COG1496@1|root,COG1496@2|Bacteria	2|Bacteria	S	copper ion binding	yfiH	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
YHH1_k127_2087343_0	1191523.MROS_2426	1.251e-175	561.0	COG0626@1|root,COG0626@2|Bacteria	2|Bacteria	E	cystathionine gamma-synthase activity	megL	-	4.4.1.1,4.4.1.11,4.4.1.8	ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R01001,R01286,R02408,R04770,R04930,R04941,R09366	RC00056,RC00069,RC00196,RC00348,RC00382,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
YHH1_k127_209248_0	1191523.MROS_0620	2.813e-58	213.0	COG1520@1|root,COG3303@1|root,COG1520@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
YHH1_k127_209248_1	32024.JMTI01000016_gene415	1.818e-37	149.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2YMTU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
YHH1_k127_209248_2	269799.Gmet_1068	1.009e-09	69.0	COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,42SBY@68525|delta/epsilon subdivisions,2WPSK@28221|Deltaproteobacteria,43V9B@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2110174_0	1336803.PHEL49_2566	2.421e-11	77.0	COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,Gly_rich,HYR,Laminin_G_3,PKD,SprB,TSP_3
YHH1_k127_2110174_1	797114.C475_06540	2.689e-09	70.0	COG2304@1|root,arCOG03991@1|root,arCOG09176@1|root,arCOG02902@2157|Archaea,arCOG03991@2157|Archaea,arCOG09176@2157|Archaea,2XVVH@28890|Euryarchaeota,23SGN@183963|Halobacteria	183963|Halobacteria	K	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
YHH1_k127_2114034_0	945713.IALB_2976	1.506e-38	152.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_2114034_1	1047013.AQSP01000130_gene1863	1.55e-35	151.0	28KQH@1|root,2ZA8A@2|Bacteria	2|Bacteria	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
YHH1_k127_2115764_0	243233.MCA0574	0.0008772	51.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1XDVY@135618|Methylococcales	135618|Methylococcales	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
YHH1_k127_2116108_1	518766.Rmar_0224	1.437e-45	170.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1FJ8P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Protein of unknown function (DUF3341)	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YHH1_k127_2116108_0	309807.SRU_2105	1.092e-184	584.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1FIWX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
YHH1_k127_2126149_2	370438.PTH_2540	2.173e-25	108.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,2609N@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YHH1_k127_2126149_4	234267.Acid_7924	2.943e-05	54.0	2BMF1@1|root,32FZM@2|Bacteria,3Y8ZK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2126149_0	357808.RoseRS_4430	1.332e-73	262.0	COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
YHH1_k127_2126149_3	1139996.OMQ_01214	2.652e-12	73.0	COG1595@1|root,COG1595@2|Bacteria,1UZSS@1239|Firmicutes,4HJ8P@91061|Bacilli	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_2126149_1	1227739.Hsw_0573	1.235e-33	136.0	2E3VP@1|root,32YSV@2|Bacteria,4NV28@976|Bacteroidetes,47S3V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2144325_0	880073.Calab_1491	5.417e-116	384.0	COG0213@1|root,COG0213@2|Bacteria,2NNXJ@2323|unclassified Bacteria	2|Bacteria	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
YHH1_k127_2144325_1	1321784.HMPREF1987_02322	7.801e-07	61.0	COG2304@1|root,COG2304@2|Bacteria,1TPAY@1239|Firmicutes,2485P@186801|Clostridia,25UBI@186804|Peptostreptococcaceae	186801|Clostridia	S	Von Willebrand factor type A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA
YHH1_k127_2148038_2	269482.Bcep1808_1665	9.833e-30	120.0	COG2350@1|root,COG2350@2|Bacteria,1MZ8Y@1224|Proteobacteria,2W38Q@28216|Betaproteobacteria,1K9C8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
YHH1_k127_2148038_0	926560.KE387023_gene2315	6.599e-65	231.0	2DBMF@1|root,2Z9YG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2148038_1	913865.DOT_1227	1.256e-37	146.0	COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,24SS3@186801|Clostridia	186801|Clostridia	O	redox protein, regulator of disulfide bond	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
YHH1_k127_2148038_3	1333523.L593_04550	1.285e-17	88.0	COG1714@1|root,arCOG03633@2157|Archaea,2XWRP@28890|Euryarchaeota,23VHA@183963|Halobacteria	183963|Halobacteria	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
YHH1_k127_2160035_2	1121930.AQXG01000001_gene1073	1.025e-34	144.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1INUW@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH1_k127_2160035_1	1121004.ATVC01000074_gene1228	3.955e-65	231.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2VHG8@28216|Betaproteobacteria,2KR0Y@206351|Neisseriales	206351|Neisseriales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
YHH1_k127_2160035_0	1191523.MROS_1377	1.186e-169	540.0	COG0192@1|root,COG0192@2|Bacteria	2|Bacteria	H	methionine adenosyltransferase activity	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YHH1_k127_2169195_1	945713.IALB_1671	4.863e-13	74.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	fahA2	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
YHH1_k127_2169195_0	1183438.GKIL_0991	2.887e-161	520.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1G0PS@1117|Cyanobacteria	1117|Cyanobacteria	H	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
YHH1_k127_2174_0	927658.AJUM01000017_gene3109	1.414e-09	66.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K20345	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	3.A.1.112,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
YHH1_k127_2192349_1	56780.SYN_00037	1.535e-44	167.0	COG5319@1|root,COG5319@2|Bacteria,1RKDX@1224|Proteobacteria,42SDV@68525|delta/epsilon subdivisions,2WPXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH1_k127_2192349_2	102129.Lepto7375DRAFT_0019	8.35e-08	63.0	COG3170@1|root,COG3170@2|Bacteria,1GDX9@1117|Cyanobacteria	1117|Cyanobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2192349_0	395961.Cyan7425_1368	2.961e-75	261.0	COG1092@1|root,COG1092@2|Bacteria,1G4YN@1117|Cyanobacteria	1117|Cyanobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
YHH1_k127_2192540_0	1122176.KB903541_gene156	3.608e-94	330.0	COG0708@1|root,COG0708@2|Bacteria,4NM12@976|Bacteroidetes	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH1_k127_2192540_1	635013.TherJR_1007	1.081e-36	147.0	COG0420@1|root,COG0420@2|Bacteria,1V9XH@1239|Firmicutes,24KAZ@186801|Clostridia,265D8@186807|Peptococcaceae	186801|Clostridia	L	PFAM metallophosphoesterase	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
YHH1_k127_2198647_0	309807.SRU_1400	1.137e-101	355.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1FIZK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2249421_1	1167006.UWK_00797	2.095e-16	86.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MJVB@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
YHH1_k127_2249421_0	1120953.AUBH01000011_gene492	1.829e-47	192.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,465HK@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	COG4796 Type II secretory pathway, component HofQ	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
YHH1_k127_2263181_0	1191523.MROS_2079	2.54e-19	105.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
YHH1_k127_2266699_0	880073.Calab_0944	5.206e-150	486.0	COG0187@1|root,COG0187@2|Bacteria,2NNSN@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH1_k127_2266699_1	1433126.BN938_1681	8.65e-28	119.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,2FMER@200643|Bacteroidia,22URH@171550|Rikenellaceae	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
YHH1_k127_2284055_0	945713.IALB_0906	0.0	1381.0	COG0086@1|root,COG0086@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH1_k127_2302766_3	945713.IALB_1374	2.675e-50	190.0	2CUTJ@1|root,32SW3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2302766_0	1191523.MROS_1698	4.867e-134	441.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
YHH1_k127_2302766_2	1191523.MROS_1697	1.252e-76	263.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	ung	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH1_k127_2302766_1	1121129.KB903367_gene2893	3.099e-113	377.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,2FNDG@200643|Bacteroidia,22X4T@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
YHH1_k127_2302766_4	1122971.BAME01000038_gene3518	1.501e-34	136.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,2FNWA@200643|Bacteroidia,22XMY@171551|Porphyromonadaceae	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
YHH1_k127_2319569_0	945713.IALB_3118	1.552e-78	291.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
YHH1_k127_2319569_1	1121889.AUDM01000013_gene1874	2.723e-23	117.0	COG4447@1|root,COG4447@2|Bacteria,4PM0K@976|Bacteroidetes,1I2DM@117743|Flavobacteriia,2NV0G@237|Flavobacterium	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_2335907_1	471854.Dfer_4466	6.889e-21	93.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,47QD7@768503|Cytophagia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
YHH1_k127_2335907_0	1191523.MROS_2293	4.996e-201	638.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria	2|Bacteria	F	GMP synthase (glutamine-hydrolyzing) activity	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.3.1.128,6.3.5.2	ko:K01951,ko:K03790	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002,ko03009	-	-	iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	GATase,GMP_synt_C,NAD_synthase
YHH1_k127_2341111_3	1262449.CP6013_0082	3.129e-10	65.0	COG1852@1|root,COG1852@2|Bacteria,1UZ1X@1239|Firmicutes,24A38@186801|Clostridia,36EPT@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116
YHH1_k127_2341111_1	330214.NIDE0521	4.478e-41	163.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
YHH1_k127_2341111_0	945713.IALB_2292	1.762e-89	304.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH1_k127_2341111_2	357808.RoseRS_0542	2.512e-34	136.0	COG1028@1|root,COG1028@2|Bacteria,2G8K5@200795|Chloroflexi,3779V@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
YHH1_k127_234464_2	1191523.MROS_2296	5.604e-30	130.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,LysM,SAM_adeno_trans,Y_phosphatase3
YHH1_k127_234464_0	945713.IALB_0816	9.817e-121	396.0	COG1702@1|root,COG1702@2|Bacteria	2|Bacteria	T	phosphate starvation-inducible protein PhoH	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
YHH1_k127_234464_3	709991.Odosp_2080	1.311e-06	56.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,2FMZK@200643|Bacteroidia,22WHJ@171551|Porphyromonadaceae	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH1_k127_234464_1	945713.IALB_1495	3.198e-94	312.0	COG1186@1|root,COG1186@2|Bacteria	2|Bacteria	J	translation release factor activity	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH1_k127_2354564_1	1123354.AUDR01000014_gene893	1.882e-20	92.0	COG1047@1|root,COG1047@2|Bacteria	2|Bacteria	O	modulation by symbiont of host adenylate cyclase-mediated signal transduction	slyD	-	5.2.1.8	ko:K01802,ko:K03774,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
YHH1_k127_2354564_2	861299.J421_1525	4.402e-20	90.0	COG1047@1|root,COG1047@2|Bacteria	2|Bacteria	O	modulation by symbiont of host adenylate cyclase-mediated signal transduction	slyD	-	5.2.1.8	ko:K01802,ko:K03774,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
YHH1_k127_2354564_0	331678.Cphamn1_1814	7.722e-28	120.0	COG4942@1|root,COG4942@2|Bacteria,1FDDK@1090|Chlorobi	1090|Chlorobi	D	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH1_k127_2356084_0	945713.IALB_1093	1.952e-250	782.0	28I8B@1|root,2Z8B5@2|Bacteria	2|Bacteria	C	PFAM Cytochrome c, bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_C7,Cytochrome_cB
YHH1_k127_2356084_2	517418.Ctha_2244	3.445e-90	304.0	COG4117@1|root,COG4117@2|Bacteria,1FDS6@1090|Chlorobi	1090|Chlorobi	C	PFAM cytochrome B561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
YHH1_k127_2356084_3	517418.Ctha_2245	3.041e-78	265.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YHH1_k127_2356084_1	945713.IALB_1096	3.722e-141	458.0	COG0607@1|root,COG2391@1|root,COG0607@2|Bacteria,COG2391@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	M1-359	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Cu_amine_oxidN1,DUF4344,Sulf_transp
YHH1_k127_2356084_4	944547.ABLL_0883	7.518e-25	105.0	COG2253@1|root,COG2253@2|Bacteria,1PZRM@1224|Proteobacteria,42SAJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH1_k127_236569_3	1185876.BN8_06682	5.3e-46	180.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,47N8D@768503|Cytophagia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
YHH1_k127_236569_2	945713.IALB_0316	1.578e-58	208.0	COG0817@1|root,COG0817@2|Bacteria	2|Bacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
YHH1_k127_236569_1	945713.IALB_0317	4.658e-87	294.0	COG0217@1|root,COG0217@2|Bacteria	2|Bacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
YHH1_k127_236569_0	1191523.MROS_0746	3.189e-98	329.0	COG0608@1|root,COG0608@2|Bacteria	2|Bacteria	L	single-stranded DNA 5'-3' exodeoxyribonuclease activity	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH1_k127_2375984_1	690850.Desaf_1097	0.0001196	55.0	COG5434@1|root,COG5434@2|Bacteria,1R1I5@1224|Proteobacteria,4320W@68525|delta/epsilon subdivisions,2WWIY@28221|Deltaproteobacteria	690850.Desaf_1097|-	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2375984_0	313603.FB2170_10111	4.628e-40	168.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
YHH1_k127_2377785_1	593117.TGAM_1346	2.234e-18	89.0	COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,243KR@183968|Thermococci	183968|Thermococci	S	Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
YHH1_k127_2377785_0	443144.GM21_3023	1.401e-25	115.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria,43VJF@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
YHH1_k127_2377785_2	471852.Tcur_1861	0.0004386	52.0	COG1075@1|root,COG1075@2|Bacteria,2GM7V@201174|Actinobacteria,4EIWC@85012|Streptosporangiales	201174|Actinobacteria	S	Lipase (class 2)	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Lipase_2
YHH1_k127_2388233_2	1191523.MROS_1340	3.986e-12	70.0	2ENTB@1|root,33GEH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2388233_1	880073.Calab_1229	9.111e-42	160.0	COG0526@1|root,COG0526@2|Bacteria,2NPYK@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin-like	resA	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Thioredoxin_8
YHH1_k127_2388233_0	1519464.HY22_00065	5.144e-81	278.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH1_k127_2394735_0	661478.OP10G_1971	1.128e-117	422.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2394735_2	97096.XP_007793390.1	2.601e-09	72.0	COG4447@1|root,2RWE9@2759|Eukaryota,3A542@33154|Opisthokonta,3P4DZ@4751|Fungi,3QTYJ@4890|Ascomycota,21CZZ@147550|Sordariomycetes	4751|Fungi	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2394735_1	661478.OP10G_1971	2.219e-98	344.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2395850_1	397278.JOJN01000019_gene2333	9.592e-16	89.0	COG2132@1|root,COG2133@1|root,COG2982@1|root,COG3291@1|root,COG3401@1|root,COG4733@1|root,COG2132@2|Bacteria,COG2133@2|Bacteria,COG2982@2|Bacteria,COG3291@2|Bacteria,COG3401@2|Bacteria,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PA14
YHH1_k127_2395850_0	880073.Calab_3225	4.636e-48	179.0	COG0170@1|root,COG1836@1|root,COG0170@2|Bacteria,COG1836@2|Bacteria,2NPNT@2323|unclassified Bacteria	2|Bacteria	I	Integral membrane protein DUF92	-	GO:0005575,GO:0016020	2.7.1.182,2.7.7.41	ko:K00981,ko:K18678	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799,R10659	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF92
YHH1_k127_243035_0	56780.SYN_00434	1.069e-12	73.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,1R6N1@1224|Proteobacteria,42NZW@68525|delta/epsilon subdivisions,2WMDS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM MCP methyltransferase, CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,TPR_16,TPR_8
YHH1_k127_243035_1	1304880.JAGB01000001_gene211	3.617e-05	53.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia	186801|Clostridia	NT	PFAM CheW domain protein	cheW2	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
YHH1_k127_2431630_0	1499967.BAYZ01000088_gene5057	8.329e-70	252.0	COG2006@1|root,COG2006@2|Bacteria,2NPBD@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YHH1_k127_2431630_1	945713.IALB_0846	1.135e-30	138.0	COG1520@1|root,COG1572@1|root,COG3291@1|root,COG4733@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,Malectin,fn3
YHH1_k127_2431630_2	926550.CLDAP_29660	0.0009726	42.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
YHH1_k127_2441940_0	504487.JCM19302_825	5.263e-26	118.0	COG1404@1|root,COG1572@1|root,COG3291@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,4NIM1@976|Bacteroidetes,1I0WD@117743|Flavobacteriia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_M43,Reprolysin_3
YHH1_k127_2452833_0	1540257.JQMW01000013_gene1221	3.828e-114	385.0	COG1215@1|root,COG1215@2|Bacteria,1TRCI@1239|Firmicutes,25BAQ@186801|Clostridia,36WCZ@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferase family 21	ydaM	-	2.4.1.336	ko:K19003	ko00561,ko01100,map00561,map01100	-	R02689	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
YHH1_k127_2452833_1	234267.Acid_0019	6.354e-44	177.0	2EY4D@1|root,33RD9@2|Bacteria,3Y6DM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2453138_2	517418.Ctha_1150	1.098e-05	48.0	COG0378@1|root,COG0378@2|Bacteria,1FDPQ@1090|Chlorobi	1090|Chlorobi	KO	TIGRFAM hydrogenase accessory protein HypB	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
YHH1_k127_2453138_1	944564.HMPREF9200_0980	1.207e-19	94.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,4H581@909932|Negativicutes	909932|Negativicutes	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
YHH1_k127_2453138_0	50452.A0A087GVP9	1.322e-24	115.0	28N0B@1|root,2QUHA@2759|Eukaryota,37HDX@33090|Viridiplantae,3GCE2@35493|Streptophyta,3HXY6@3699|Brassicales	35493|Streptophyta	S	EamA-like transporter family	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_2456820_0	439235.Dalk_3544	7.3e-48	197.0	29RQM@1|root,30CU4@2|Bacteria,1NU3F@1224|Proteobacteria,42YUA@68525|delta/epsilon subdivisions,2WUNP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2458074_0	880073.Calab_3681	1.942e-198	625.0	COG3051@1|root,COG3051@2|Bacteria,2NP8D@2323|unclassified Bacteria	2|Bacteria	C	Citrate lyase, alpha subunit (CitF)	citF	-	2.8.3.10	ko:K01643	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	CitF
YHH1_k127_2458074_1	945713.IALB_1147	8.311e-141	460.0	COG2301@1|root,COG3052@1|root,COG2301@2|Bacteria,COG3052@2|Bacteria	2|Bacteria	C	prosthetic group binding	citD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008815,GO:0009346,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0032991,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	4.1.3.25,4.1.3.34	ko:K01644,ko:K01646,ko:K18292	ko00660,ko01100,ko02020,map00660,map01100,map02020	-	R00237,R00362	RC00067,RC00502,RC01118,RC01205	ko00000,ko00001,ko01000	-	-	-	ACP,HpcH_HpaI
YHH1_k127_2472984_1	1687.BCOR_0185	0.000117	55.0	COG5184@1|root,COG5184@2|Bacteria,2IDH9@201174|Actinobacteria,4D0CR@85004|Bifidobacteriales	201174|Actinobacteria	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,RCC1,RCC1_2
YHH1_k127_2491171_1	1345023.M467_01580	9.035e-15	85.0	COG0170@1|root,COG0170@2|Bacteria,1UJ3I@1239|Firmicutes	1239|Firmicutes	I	dolichyl monophosphate biosynthetic process	-	-	2.7.1.182	ko:K18678	-	-	R10659	RC00002,RC00017	ko00000,ko01000	-	-	-	-
YHH1_k127_2491171_0	941449.dsx2_1731	2.261e-19	101.0	COG1462@1|root,COG2885@1|root,COG1462@2|Bacteria,COG2885@2|Bacteria,1R6QU@1224|Proteobacteria,43DMJ@68525|delta/epsilon subdivisions,2X6A2@28221|Deltaproteobacteria,2MH0J@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
YHH1_k127_2514213_5	517418.Ctha_2584	5.17e-20	106.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.62	ko:K01342,ko:K12287,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02044,ko03110	-	-	-	FG-GAP,Peptidase_S8,VCBS
YHH1_k127_2514213_4	1121930.AQXG01000031_gene1647	7.472e-21	109.0	COG1319@1|root,COG1520@1|root,COG2911@1|root,COG3291@1|root,COG1319@2|Bacteria,COG1520@2|Bacteria,COG2911@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.1.3.1	ko:K01113,ko:K20274	ko00790,ko01100,ko02020,ko02024,map00790,map01100,map02020,map02024	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	FAD_binding_5
YHH1_k127_2514213_1	509635.N824_16125	1.244e-32	132.0	COG3620@1|root,COG3620@2|Bacteria,4PNCJ@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2514213_0	1123057.P872_07530	1.222e-78	270.0	COG2184@1|root,COG2184@2|Bacteria,4NM5F@976|Bacteroidetes,47PH8@768503|Cytophagia	976|Bacteroidetes	D	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH1_k127_2514213_2	1229205.BUPH_04880	4.37e-31	127.0	2E6BD@1|root,330Z6@2|Bacteria,1NP2W@1224|Proteobacteria,2W42N@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2514213_3	686340.Metal_3029	3.624e-25	106.0	COG1724@1|root,COG1724@2|Bacteria,1P3W9@1224|Proteobacteria,1SSC4@1236|Gammaproteobacteria,1XGPG@135618|Methylococcales	135618|Methylococcales	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH1_k127_2514213_6	340177.Cag_0455	6.486e-20	91.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2519103_0	906888.JCM19314_2994	2.109e-85	286.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia,3HJ5J@363408|Nonlabens	976|Bacteroidetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YHH1_k127_2519103_1	644282.Deba_3185	2.117e-57	205.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,42QQE@68525|delta/epsilon subdivisions,2WNC3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YHH1_k127_2519103_2	1158318.ATXC01000001_gene300	5.236e-05	53.0	COG0147@1|root,COG0147@2|Bacteria	2|Bacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	pabB	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iEC042_1314.EC042_1977	Aminotran_4,Anth_synt_I_N,Chorismate_bind,GATase
YHH1_k127_2527733_1	1121930.AQXG01000004_gene2870	3.188e-17	94.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
YHH1_k127_2527733_0	1121930.AQXG01000023_gene1642	1.874e-19	103.0	COG0737@1|root,COG2374@1|root,COG0737@2|Bacteria,COG2374@2|Bacteria,4PPNB@976|Bacteroidetes,1IY1S@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	-	-	-	-	-	-	-	-	-	-	-	-	LTD
YHH1_k127_2537757_0	1121930.AQXG01000016_gene1824	1.793e-120	400.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1IPB4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	yheS_3	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH1_k127_2541839_0	945713.IALB_1745	7.596e-137	439.0	COG0162@1|root,COG0162@2|Bacteria	2|Bacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iJN746.PP_0436,iLJ478.TM0478	S4,tRNA-synt_1b
YHH1_k127_2541839_1	246194.CHY_0290	5.368e-51	186.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,42GC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YHH1_k127_2541839_3	1191523.MROS_1716	1.608e-18	91.0	COG0779@1|root,COG0779@2|Bacteria	2|Bacteria	S	ribosomal small subunit biogenesis	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
YHH1_k127_2541839_2	945713.IALB_0638	1.561e-21	95.0	COG0195@1|root,COG0195@2|Bacteria	2|Bacteria	K	DNA-templated transcription, termination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
YHH1_k127_2558874_0	290402.Cbei_1197	5.238e-133	434.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,36DRW@31979|Clostridiaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
YHH1_k127_2558874_2	1191523.MROS_1922	2.954e-69	246.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH1_k127_2558874_1	290512.Paes_2276	4.052e-73	250.0	COG0126@1|root,COG0126@2|Bacteria,1FDBD@1090|Chlorobi	1090|Chlorobi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
YHH1_k127_2579251_1	1487953.JMKF01000048_gene2058	2.283e-21	95.0	COG2183@1|root,COG2183@2|Bacteria,1G12X@1117|Cyanobacteria,1H7FA@1150|Oscillatoriales	1117|Cyanobacteria	K	Transcriptional accessory protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
YHH1_k127_2579251_2	1122176.KB903533_gene2257	1.513e-08	61.0	28R0A@1|root,2ZDF0@2|Bacteria,4P70A@976|Bacteroidetes,1IZF3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2579251_0	1469948.JPNB01000001_gene955	3.698e-118	388.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,36GDB@31979|Clostridiaceae	186801|Clostridia	L	PFAM transposase, mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
YHH1_k127_2581557_1	448385.sce4867	2.986e-47	177.0	COG4124@1|root,COG4124@2|Bacteria,1QH7T@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Glyco_hydro_26
YHH1_k127_2581557_0	247490.KSU1_C0449	2.073e-89	315.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
YHH1_k127_2581557_2	1121957.ATVL01000009_gene1033	1.982e-07	64.0	COG2911@1|root,COG2931@1|root,COG3391@1|root,COG4677@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,COG4677@2|Bacteria,4PMEU@976|Bacteroidetes,47RH2@768503|Cytophagia	976|Bacteroidetes	G	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Laminin_G_3
YHH1_k127_263053_0	880073.Calab_2897	2.912e-12	76.0	COG0737@1|root,COG1404@1|root,COG2304@1|root,COG0737@2|Bacteria,COG1404@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	xynX5	-	3.2.1.8,3.4.21.66	ko:K01181,ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,Peptidase_S8_N,SLH
YHH1_k127_2662392_1	1121439.dsat_0907	2.456e-23	101.0	COG0697@1|root,COG0697@2|Bacteria,1QBAD@1224|Proteobacteria,42PAK@68525|delta/epsilon subdivisions,2WKBB@28221|Deltaproteobacteria,2M8G9@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_2662392_0	1313301.AUGC01000018_gene788	5.524e-73	266.0	COG5360@1|root,COG5360@2|Bacteria,4PPDG@976|Bacteroidetes	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2662392_2	1125863.JAFN01000001_gene170	3.149e-12	67.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YHH1_k127_267050_1	880073.Calab_1670	1.022e-49	183.0	COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	csdA	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YHH1_k127_267050_3	869210.Marky_1775	4.247e-32	128.0	COG1993@1|root,COG1993@2|Bacteria,1WKB2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
YHH1_k127_267050_4	404380.Gbem_0702	2.417e-31	127.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
YHH1_k127_267050_2	1278078.G419_22769	3.12e-33	138.0	COG1028@1|root,COG1028@2|Bacteria,2IFUD@201174|Actinobacteria,4FYUB@85025|Nocardiaceae	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ywfD	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
YHH1_k127_267050_0	1297742.A176_01297	3.009e-86	293.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54,5.4.99.5	ko:K01626,ko:K03856,ko:K04516,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
YHH1_k127_2680381_2	945713.IALB_0533	1.552e-31	129.0	COG0745@1|root,COG0745@2|Bacteria	945713.IALB_0533|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2680381_0	1191523.MROS_2482	5.284e-234	736.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria	2|Bacteria	C	iron-sulfur cluster assembly	-	-	1.12.1.2,1.12.1.3,1.6.5.3	ko:K00336,ko:K18006,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_6,Fer4_7,Fer4_9,NADH-G_4Fe-4S_3,Pyr_redox_2
YHH1_k127_2680381_1	1191523.MROS_2481	1.684e-192	606.0	COG1894@1|root,COG3411@1|root,COG1894@2|Bacteria,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	hoxF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K05587,ko:K17992,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
YHH1_k127_2681880_1	1321778.HMPREF1982_00035	1.38e-145	484.0	COG2511@1|root,COG2511@2|Bacteria,1UPG0@1239|Firmicutes,25HFT@186801|Clostridia	186801|Clostridia	J	GatB/GatE catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GatB_N
YHH1_k127_2681880_0	1499683.CCFF01000013_gene324	7.969e-218	685.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,36EB6@31979|Clostridiaceae	186801|Clostridia	EJ	L-asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
YHH1_k127_2681880_2	1121272.KB903249_gene1521	3.937e-06	59.0	COG1404@1|root,COG2133@1|root,COG3291@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria,4DASA@85008|Micromonosporales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CarboxypepD_reg,F5_F8_type_C,GSDH,PA14,PKD
YHH1_k127_2707517_0	309807.SRU_2713	4.01e-09	62.0	COG3210@1|root,COG4412@1|root,COG3210@2|Bacteria,COG4412@2|Bacteria,4PEZ5@976|Bacteroidetes,1FJW1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,Laminin_G_3
YHH1_k127_2707517_1	269799.Gmet_1068	2.419e-07	61.0	COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,42SBY@68525|delta/epsilon subdivisions,2WPSK@28221|Deltaproteobacteria,43V9B@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2719840_0	1120966.AUBU01000006_gene3469	5.257e-70	245.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,47MHF@768503|Cytophagia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
YHH1_k127_2719840_1	338963.Pcar_2070	5.637e-53	196.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,42RE2@68525|delta/epsilon subdivisions,2WNEN@28221|Deltaproteobacteria,43THX@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
YHH1_k127_2719840_2	1121930.AQXG01000005_gene601	1.726e-16	82.0	COG1404@1|root,COG1404@2|Bacteria,4NVH2@976|Bacteroidetes,1IURU@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2726459_0	945713.IALB_0942	9.992e-59	224.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	pleD	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GGDEF,Response_reg
YHH1_k127_2730757_0	945713.IALB_0831	2.254e-75	264.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
YHH1_k127_2730757_1	1300345.LF41_2548	5.015e-38	155.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,1X3WH@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
YHH1_k127_2731785_1	926562.Oweho_1511	9.527e-33	134.0	COG0697@1|root,COG0697@2|Bacteria,4NDYH@976|Bacteroidetes,1HXMM@117743|Flavobacteriia,2PAR1@246874|Cryomorphaceae	976|Bacteroidetes	EG	EamA-like transporter family	sam	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
YHH1_k127_2731785_2	1385935.N836_16225	9.53e-30	129.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
YHH1_k127_2731785_0	945713.IALB_1608	2.214e-103	345.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH1_k127_2735699_1	1121930.AQXG01000006_gene772	2.416e-48	176.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,1IT6I@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
YHH1_k127_2735699_0	1191523.MROS_0436	4.497e-144	467.0	COG0465@1|root,COG0465@2|Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YHH1_k127_2737382_1	945713.IALB_1511	8.858e-46	171.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
YHH1_k127_2737382_0	945713.IALB_1512	1.186e-72	257.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	iLJ478.TM1264	PBP_like_2
YHH1_k127_2737382_2	880073.Calab_2983	3.664e-33	132.0	COG0542@1|root,COG0542@2|Bacteria,2NNNE@2323|unclassified Bacteria	2|Bacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH1_k127_2756235_1	517418.Ctha_2287	1.26e-115	390.0	COG1173@1|root,COG1173@2|Bacteria,1FD9T@1090|Chlorobi	1090|Chlorobi	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
YHH1_k127_2756235_2	517418.Ctha_1639	3.759e-109	361.0	COG0601@1|root,COG0601@2|Bacteria,1FDDB@1090|Chlorobi	1090|Chlorobi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
YHH1_k127_2756235_0	517418.Ctha_1641	2.052e-147	484.0	COG0747@1|root,COG0747@2|Bacteria,1FD6U@1090|Chlorobi	1090|Chlorobi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YHH1_k127_2756235_3	1191523.MROS_2541	2.46e-65	226.0	COG1493@1|root,COG1493@2|Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
YHH1_k127_2757737_1	517418.Ctha_0849	4.845e-89	299.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1FDD7@1090|Chlorobi	1090|Chlorobi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
YHH1_k127_2757737_0	452637.Oter_3305	7.023e-98	338.0	COG1884@1|root,COG1884@2|Bacteria,46UTP@74201|Verrucomicrobia,3K7BG@414999|Opitutae	414999|Opitutae	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
YHH1_k127_2782291_0	479434.Sthe_1432	7.277e-27	118.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi,27YM4@189775|Thermomicrobia	189775|Thermomicrobia	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
YHH1_k127_2782291_1	880073.Calab_1116	5.641e-13	76.0	COG0526@1|root,COG3693@1|root,COG0526@2|Bacteria,COG3693@2|Bacteria	2|Bacteria	G	endo-1,4-beta-xylanase activity	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	AhpC-TSA,Glyco_hydro_10,Glyco_hydro_39,Omp28
YHH1_k127_2784571_1	945713.IALB_1511	8.937e-93	317.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
YHH1_k127_2784571_2	861299.J421_3681	8.89e-10	63.0	COG2608@1|root,COG2608@2|Bacteria,1ZU70@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
YHH1_k127_2784571_0	42256.RradSPS_1697	1.231e-150	498.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
YHH1_k127_2787479_0	1089547.KB913013_gene2846	1.266e-161	547.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,47MX4@768503|Cytophagia	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	npr	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,MAM,PepSY,Peptidase_M4,Peptidase_M4_C,fn3
YHH1_k127_2787479_1	945713.IALB_1645	1.136e-57	207.0	2E2T1@1|root,32XVB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2793723_0	1124780.ANNU01000048_gene2129	2.399e-157	510.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
YHH1_k127_2798276_0	1086011.HJ01_00611	1.594e-17	93.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia,2NTFQ@237|Flavobacterium	976|Bacteroidetes	M	transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
YHH1_k127_2798276_1	1552123.EP57_10840	0.0007777	51.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,26JEW@186820|Listeriaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
YHH1_k127_2810047_2	398767.Glov_2747	9.157e-12	67.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1RDAK@1224|Proteobacteria,42U4I@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
YHH1_k127_2810047_1	748247.AZKH_3593	7.308e-56	207.0	28PGR@1|root,30B07@2|Bacteria,1NBDP@1224|Proteobacteria,2W4CF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
YHH1_k127_2810047_0	41431.PCC8801_2037	7.197e-80	274.0	COG4122@1|root,COG4122@2|Bacteria,1G4B7@1117|Cyanobacteria	1117|Cyanobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
YHH1_k127_2844939_0	518766.Rmar_0923	8.757e-290	904.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1FIM5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EI	ArgK protein	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
YHH1_k127_2844939_1	869213.JCM21142_41386	3.283e-44	171.0	COG2043@1|root,COG2043@2|Bacteria	2|Bacteria	C	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
YHH1_k127_2844939_2	1341151.ASZU01000010_gene1963	3.484e-15	84.0	COG1250@1|root,COG1250@2|Bacteria,1TSZI@1239|Firmicutes,4HBK3@91061|Bacilli,27BQM@186824|Thermoactinomycetaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
YHH1_k127_2862753_2	761193.Runsl_4128	5.968e-48	179.0	COG0500@1|root,COG1246@1|root,COG1246@2|Bacteria,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,47MVN@768503|Cytophagia	976|Bacteroidetes	Q	Hypothetical methyltransferase	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
YHH1_k127_2862753_1	391625.PPSIR1_04148	1.026e-59	216.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc,PhoU
YHH1_k127_2862753_0	926569.ANT_08560	1.158e-165	527.0	COG0798@1|root,COG0798@2|Bacteria,2G5ZH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
YHH1_k127_2898326_0	1267535.KB906767_gene1959	8.004e-11	63.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_2898326_2	1121104.AQXH01000002_gene747	0.0004119	48.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1IXY7@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,MAM,TIG,fn3
YHH1_k127_2898326_1	187272.Mlg_2394	1.879e-05	54.0	COG2304@1|root,COG2304@2|Bacteria,1P8UT@1224|Proteobacteria	1224|Proteobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
YHH1_k127_2945718_0	1307761.L21SP2_2601	4.002e-64	229.0	28JYD@1|root,2Z9NN@2|Bacteria	1307761.L21SP2_2601|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2945718_2	1121930.AQXG01000016_gene1820	1.76e-07	63.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,1ITNU@117747|Sphingobacteriia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_2945718_1	1288963.ADIS_2524	1.704e-20	102.0	COG0589@1|root,COG0589@2|Bacteria,4NGG8@976|Bacteroidetes	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YHH1_k127_2951675_0	1121930.AQXG01000001_gene1165	2.061e-13	83.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Laminin_G_3
YHH1_k127_2997228_2	1313172.YM304_38210	2.92e-05	51.0	COG3276@1|root,COG3276@2|Bacteria,2I7V8@201174|Actinobacteria	201174|Actinobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,SelB-wing_3
YHH1_k127_2997228_1	1047013.AQSP01000096_gene2181	2.244e-08	64.0	COG1618@1|root,COG1618@2|Bacteria	2|Bacteria	F	nucleotide phosphatase activity, acting on free nucleotides	mobA	-	2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34	ko:K00943,ko:K02013,ko:K02017,ko:K03574,ko:K03752,ko:K06928	ko00230,ko00240,ko00730,ko00790,ko01100,ko02010,map00230,map00240,map00730,map00790,map01100,map02010	M00053,M00189,M00240	R00086,R00615,R02094,R02098,R11581	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.14,3.A.1.8	-	-	DUF2478,NTPase_1
YHH1_k127_2997228_0	75379.Tint_0204	7.37e-27	125.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1QVD1@1224|Proteobacteria,2WGQY@28216|Betaproteobacteria,1KN64@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH1_k127_2997909_1	1519464.HY22_09345	4.457e-83	281.0	COG1236@1|root,COG1236@2|Bacteria,1FER3@1090|Chlorobi	1090|Chlorobi	J	PFAM beta-lactamase domain protein	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
YHH1_k127_2997909_0	517418.Ctha_2297	1.424e-264	835.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1FEVC@1090|Chlorobi	1090|Chlorobi	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
YHH1_k127_2997909_2	945713.IALB_0305	1.81e-26	111.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH1_k127_3008735_1	1200792.AKYF01000026_gene163	6.273e-05	56.0	COG4932@1|root,COG4932@2|Bacteria,1UJQY@1239|Firmicutes,4ITDJ@91061|Bacilli,270X3@186822|Paenibacillaceae	91061|Bacilli	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YHH1_k127_3008735_0	518766.Rmar_0508	7.214e-117	405.0	COG2203@1|root,COG2204@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FJ5I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	Sigma54_activat
YHH1_k127_3019983_0	330214.NIDE3276	0.0	1044.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,PqqD,Radical_SAM
YHH1_k127_3039943_1	1411685.U062_01308	3.122e-86	292.0	COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,1T1SF@1236|Gammaproteobacteria,1J5SF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0668 Small-conductance mechanosensitive channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
YHH1_k127_3039943_4	933115.GPDM_15409	4.184e-33	138.0	COG0500@1|root,COG0500@2|Bacteria,1UIE3@1239|Firmicutes,4IT9T@91061|Bacilli,26EQH@186818|Planococcaceae	91061|Bacilli	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH1_k127_3039943_5	56107.Cylst_2548	5.496e-10	68.0	2E3GU@1|root,32YFI@2|Bacteria,1G9HI@1117|Cyanobacteria,1HP28@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3039943_0	448385.sce1086	2.068e-152	500.0	COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2YW51@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
YHH1_k127_3039943_2	1192034.CAP_5079	1.788e-79	276.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2Z073@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YHH1_k127_3039943_3	395493.BegalDRAFT_1106	6.905e-54	209.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria,1T2D4@1236|Gammaproteobacteria,463V1@72273|Thiotrichales	1236|Gammaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF,HATPase_c,HisKA,Response_reg
YHH1_k127_3044895_1	945713.IALB_1764	6.523e-35	140.0	COG5448@1|root,COG5448@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
YHH1_k127_3044895_0	1121920.AUAU01000004_gene585	7.524e-100	339.0	COG2309@1|root,COG2309@2|Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
YHH1_k127_3044895_5	305900.GV64_00255	7.4e-11	65.0	COG3077@1|root,COG3077@2|Bacteria,1NGDT@1224|Proteobacteria,1T16N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
YHH1_k127_3044895_4	211165.AJLN01000096_gene5031	7.24e-23	102.0	COG2337@1|root,COG2337@2|Bacteria,1GE2Z@1117|Cyanobacteria	1117|Cyanobacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3044895_2	1254432.SCE1572_02625	4.722e-34	136.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1N3KK@1224|Proteobacteria,42TH7@68525|delta/epsilon subdivisions,2WQ6A@28221|Deltaproteobacteria,2YVVZ@29|Myxococcales	28221|Deltaproteobacteria	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,GIY-YIG,HTH_20
YHH1_k127_3044895_3	649638.Trad_2634	1.252e-31	126.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
YHH1_k127_3046312_0	945713.IALB_1857	3.205e-30	136.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
YHH1_k127_3047026_4	1280696.ATVY01000021_gene1843	1.606e-22	97.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,4BW4R@830|Butyrivibrio	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH1_k127_3047026_3	883.DvMF_2832	1.983e-26	113.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2MBW9@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
YHH1_k127_3047026_0	945713.IALB_1619	5.515e-111	370.0	COG0836@1|root,COG0836@2|Bacteria	2|Bacteria	M	mannose-1-phosphate guanylyltransferase activity	manC	-	2.7.7.13,5.3.1.8,5.4.2.8	ko:K00971,ko:K01840,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01818,R01819	RC00002,RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00940	MannoseP_isomer,NTP_transferase
YHH1_k127_3047026_2	1452718.JBOY01000059_gene1585	3.372e-31	128.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
YHH1_k127_3047026_1	1117108.PAALTS15_10304	8.771e-53	204.0	COG0726@1|root,COG0726@2|Bacteria,1VI89@1239|Firmicutes,4HTU2@91061|Bacilli,26XPW@186822|Paenibacillaceae	91061|Bacilli	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3047026_5	945713.IALB_0737	4.391e-19	89.0	2EAR5@1|root,334TB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3055714_0	945713.IALB_2347	1.209e-97	346.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
YHH1_k127_3059828_1	945713.IALB_0380	3.901e-56	200.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	ybaK	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
YHH1_k127_3059828_0	713586.KB900536_gene673	2.212e-186	593.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RRI0@1236|Gammaproteobacteria,1WX76@135613|Chromatiales	135613|Chromatiales	E	lysine 2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3076688_0	945713.IALB_0822	4.09e-110	366.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	vicK	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K07709,ko:K13924	ko02020,ko02030,map02020,map02030	M00499,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
YHH1_k127_3089231_0	304371.MCP_2389	5.982e-104	344.0	COG4870@1|root,arCOG03614@2157|Archaea,2XZI4@28890|Euryarchaeota,2NAH7@224756|Methanomicrobia	224756|Methanomicrobia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
YHH1_k127_3089231_2	1174528.JH992890_gene540	2.142e-97	327.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
YHH1_k127_3089231_1	1303518.CCALI_01225	2.58e-102	366.0	28MB8@1|root,2ZAPS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3090494_6	929703.KE386491_gene1442	2.056e-06	54.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,47KAA@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3090494_0	1191523.MROS_0406	1.925e-131	426.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2,Thioredoxin
YHH1_k127_3090494_1	696747.NIES39_O07150	3.286e-100	336.0	COG1600@1|root,COG1600@2|Bacteria,1G007@1117|Cyanobacteria,1H7UP@1150|Oscillatoriales	1117|Cyanobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
YHH1_k127_3090494_5	314230.DSM3645_25634	5.664e-16	85.0	COG2146@1|root,COG2146@2|Bacteria,2J0ZZ@203682|Planctomycetes	203682|Planctomycetes	P	COG2146 Ferredoxin subunits of nitrite reductase and	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
YHH1_k127_3090494_2	1191523.MROS_0410	2.045e-90	306.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH1_k127_3090494_3	1191523.MROS_0412	6.302e-57	199.0	COG1139@1|root,COG1139@2|Bacteria	2|Bacteria	C	lactate oxidation	-	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	CCG,Fer4_17,Fer4_22,FrhB_FdhB_C
YHH1_k127_3090494_4	517418.Ctha_1522	5.302e-18	87.0	COG1547@1|root,COG1547@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF309)	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
YHH1_k127_3106744_0	1519464.HY22_06070	9.398e-96	327.0	COG1304@1|root,COG1304@2|Bacteria,1FDB6@1090|Chlorobi	1090|Chlorobi	F	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
YHH1_k127_3106744_1	1519464.HY22_06065	1.735e-86	301.0	COG0142@1|root,COG0142@2|Bacteria,1FDTY@1090|Chlorobi	1090|Chlorobi	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH1_k127_3106744_3	518766.Rmar_1236	4.869e-30	122.0	COG1925@1|root,COG1925@2|Bacteria,4NZ3F@976|Bacteroidetes,1FJGF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
YHH1_k127_3106744_2	941824.TCEL_00588	4.113e-76	267.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
YHH1_k127_3115739_1	404589.Anae109_3731	8.501e-40	160.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
YHH1_k127_3115739_3	1408422.JHYF01000011_gene3399	2.576e-12	74.0	COG3478@1|root,COG3478@2|Bacteria,1VKSK@1239|Firmicutes,24WD3@186801|Clostridia	186801|Clostridia	S	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3115739_0	945713.IALB_1781	1.911e-215	692.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	phuR	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_3115739_2	945713.IALB_1780	9.19e-33	133.0	2C26A@1|root,33DD0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3127329_1	1191523.MROS_1228	7.023e-35	139.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_3127329_2	1145276.T479_02495	1.714e-15	91.0	COG0810@1|root,COG4932@1|root,COG0810@2|Bacteria,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3IVXF@400634|Lysinibacillus	91061|Bacilli	M	Collagen binding domain	-	-	-	ko:K14192	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,Cna_B,Collagen_bind,Gram_pos_anchor,YSIRK_signal
YHH1_k127_3127329_0	349521.HCH_00108	8.473e-223	705.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1XH7K@135619|Oceanospirillales	135619|Oceanospirillales	C	NADH-quinone oxidoreductase subunit F	-	-	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S
YHH1_k127_316775_5	1246474.ANBE01000049_gene1388	8.237e-10	67.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4EJ56@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
YHH1_k127_316775_3	945713.IALB_1995	3.257e-18	85.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
YHH1_k127_316775_2	768710.DesyoDRAFT_4481	2.292e-87	299.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
YHH1_k127_316775_0	945713.IALB_1993	1.896e-144	464.0	COG0332@1|root,COG0332@2|Bacteria	2|Bacteria	I	beta-ketoacyl-acyl-carrier-protein synthase III activity	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
YHH1_k127_316775_1	880073.Calab_0619	3.226e-103	345.0	COG0331@1|root,COG0331@2|Bacteria,2NP3V@2323|unclassified Bacteria	2|Bacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15327,ko:K15329,ko:K15355,ko:K15469	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Acyl_transf_1
YHH1_k127_3184977_1	330214.NIDE1011	7.156e-50	180.0	COG0760@1|root,COG0760@2|Bacteria,3J1BR@40117|Nitrospirae	40117|Nitrospirae	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	SurA_N_3
YHH1_k127_3184977_0	330214.NIDE1010	1.155e-115	381.0	COG0809@1|root,COG0809@2|Bacteria,3J0HB@40117|Nitrospirae	40117|Nitrospirae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
YHH1_k127_3184977_2	330214.NIDE1009	4.144e-36	138.0	COG2385@1|root,COG2385@2|Bacteria,3J15K@40117|Nitrospirae	40117|Nitrospirae	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
YHH1_k127_318504_3	926549.KI421517_gene3854	1.912e-07	53.0	COG0718@1|root,COG0718@2|Bacteria,4NQ37@976|Bacteroidetes,47R3V@768503|Cytophagia	976|Bacteroidetes	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
YHH1_k127_318504_0	1379698.RBG1_1C00001G1657	3.43e-76	260.0	COG0353@1|root,COG0353@2|Bacteria,2NP5N@2323|unclassified Bacteria	2|Bacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
YHH1_k127_318504_1	1089550.ATTH01000001_gene1793	3.421e-56	204.0	COG0500@1|root,COG0500@2|Bacteria,4NFKM@976|Bacteroidetes,1FJ6K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31,TehB
YHH1_k127_318504_2	1191523.MROS_2703	3.213e-20	98.0	2EGU2@1|root,33AK8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_318504_4	1347342.BN863_19230	1.204e-06	51.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
YHH1_k127_3187590_0	931626.Awo_c32170	2.195e-305	965.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,25ZUT@186806|Eubacteriaceae	186801|Clostridia	H	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH1_k127_3187590_1	459349.CLOAM1530	2.808e-136	441.0	COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12,1.2.1.59,1.4.1.16	ko:K00134,ko:K00150,ko:K03340	ko00010,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00526,M00552	R01061,R01063,R02755	RC00006,RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	DapB_N,Gp_dh_C,Gp_dh_N
YHH1_k127_3224260_1	1110697.NCAST_20_05180	5.438e-08	64.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria,4FX4Z@85025|Nocardiaceae	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
YHH1_k127_3224260_0	504472.Slin_5489	1.057e-30	128.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,47QG6@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_3236774_0	1499967.BAYZ01000009_gene5315	3.002e-58	214.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07216,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	AAA_16,GAF,GAF_2,Guanylate_cyc,HATPase_c,Hemerythrin,HisKA,PAS,PAS_4,PAS_9,Pkinase,Response_reg,SpoIIE
YHH1_k127_3236774_1	118161.KB235922_gene4904	1.691e-49	179.0	COG0784@1|root,COG0784@2|Bacteria,1G6SZ@1117|Cyanobacteria,3VJW3@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH1_k127_3236774_2	204669.Acid345_1922	2.278e-31	127.0	COG2259@1|root,COG2259@2|Bacteria,3Y4XF@57723|Acidobacteria,2JMZV@204432|Acidobacteriia	204432|Acidobacteriia	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
YHH1_k127_3245191_1	1122194.AUHU01000003_gene2203	4.212e-63	220.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,466DD@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2818 3-methyladenine DNA glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
YHH1_k127_3245191_2	945713.IALB_1893	3.237e-47	177.0	COG3117@1|root,COG3117@2|Bacteria	2|Bacteria	P	lipopolysaccharide transmembrane transporter activity	lptC	-	-	ko:K09774,ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
YHH1_k127_3245191_0	1150600.ADIARSV_1037	1.53e-143	463.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,1IR3Y@117747|Sphingobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YHH1_k127_3245191_3	575540.Isop_3307	4.437e-28	115.0	COG1446@1|root,COG1446@2|Bacteria,2IZ4V@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2,DUF4440
YHH1_k127_3255006_0	323848.Nmul_A1408	6.378e-10	70.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria,372KF@32003|Nitrosomonadales	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH1_k127_3281217_1	1370122.JHXQ01000003_gene1350	6.052e-32	135.0	COG1922@1|root,COG1922@2|Bacteria,1RDA6@1224|Proteobacteria,2U8S9@28211|Alphaproteobacteria,4B6YD@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the glycosyltransferase 26 family	cpsF	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WecB
YHH1_k127_3281217_0	497964.CfE428DRAFT_4840	1.488e-131	429.0	COG0606@1|root,COG0606@2|Bacteria,46SAK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH1_k127_3342912_1	522306.CAP2UW1_3243	5.637e-66	242.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2VNRJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
YHH1_k127_3342912_0	330214.NIDE2400	1.181e-73	258.0	COG0438@1|root,COG0438@2|Bacteria,3J14A@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YHH1_k127_3352508_0	56780.SYN_01953	1.817e-76	261.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_3352508_3	468059.AUHA01000002_gene949	6.767e-46	190.0	COG4585@1|root,COG4585@2|Bacteria,4NG0M@976|Bacteroidetes,1IXEX@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	narQ	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,PilJ
YHH1_k127_3352508_1	1535422.ND16A_0651	2.499e-71	271.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K03407,ko:K07678	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg
YHH1_k127_3352508_4	926569.ANT_28850	6.862e-46	171.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	ycaO	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
YHH1_k127_3352508_5	693746.OBV_17850	6.024e-21	96.0	COG2261@1|root,COG2261@2|Bacteria,1VEUE@1239|Firmicutes,24RAN@186801|Clostridia	186801|Clostridia	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
YHH1_k127_3352508_2	313606.M23134_02636	8.301e-61	215.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,47M72@768503|Cytophagia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YHH1_k127_3363494_6	945713.IALB_0923	7.407e-09	57.0	COG0198@1|root,COG0198@2|Bacteria	2|Bacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
YHH1_k127_3363494_0	1191523.MROS_0204	3.815e-74	255.0	COG0094@1|root,COG0094@2|Bacteria	2|Bacteria	J	tRNA binding	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
YHH1_k127_3363494_5	880073.Calab_2139	1.334e-23	100.0	COG0199@1|root,COG0199@2|Bacteria,2NPW7@2323|unclassified Bacteria	2|Bacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
YHH1_k127_3363494_3	1191523.MROS_0202	2e-45	167.0	COG0096@1|root,COG0096@2|Bacteria	2|Bacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
YHH1_k127_3363494_2	523794.Lebu_0254	3.436e-59	209.0	COG0097@1|root,COG0097@2|Bacteria,3784U@32066|Fusobacteria	32066|Fusobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
YHH1_k127_3363494_4	945713.IALB_0928	1.972e-35	138.0	COG0256@1|root,COG0256@2|Bacteria	2|Bacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
YHH1_k127_3363494_1	1191523.MROS_0199	4.175e-71	243.0	COG0098@1|root,COG0098@2|Bacteria	2|Bacteria	J	rRNA binding	rpsE	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
YHH1_k127_3363494_7	945713.IALB_0930	6.727e-06	48.0	COG1841@1|root,COG1841@2|Bacteria	2|Bacteria	J	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
YHH1_k127_3367060_1	377629.TERTU_1521	1.072e-10	67.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,2PPHH@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	KT	GAF domain	nifA	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
YHH1_k127_3367060_0	522772.Dacet_1803	4.233e-125	408.0	COG2230@1|root,COG2230@2|Bacteria,2GENQ@200930|Deferribacteres	200930|Deferribacteres	H	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
YHH1_k127_3367187_1	518766.Rmar_2366	1.473e-135	451.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1FIKX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YHH1_k127_3367187_2	517418.Ctha_2628	6.14e-13	72.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1FENW@1090|Chlorobi	1090|Chlorobi	MU	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_MA_2
YHH1_k127_3367187_0	1519464.HY22_10215	1.324e-148	478.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1FENW@1090|Chlorobi	1090|Chlorobi	MU	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_MA_2
YHH1_k127_3376538_0	1191523.MROS_0381	4.968e-121	399.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria	2|Bacteria	M	arabinose-5-phosphate isomerase activity	kdsD	-	2.5.1.55,5.3.1.13	ko:K01627,ko:K03281,ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530,R03254	RC00435,RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	2.A.49	-	iAF987.Gmet_1278	CBS,SIS
YHH1_k127_3376538_1	682795.AciX8_3395	3.475e-90	306.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,3Y3YD@57723|Acidobacteria,2JIG8@204432|Acidobacteriia	204432|Acidobacteriia	E	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
YHH1_k127_3387559_0	502025.Hoch_4734	2.91e-109	369.0	COG1164@1|root,COG1164@2|Bacteria,1Q3C4@1224|Proteobacteria,4393F@68525|delta/epsilon subdivisions,2X49B@28221|Deltaproteobacteria,2YYJ7@29|Myxococcales	28221|Deltaproteobacteria	E	Oligoendopeptidase f	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3387559_1	1191523.MROS_1441	1.511e-76	267.0	2AMSR@1|root,31CP7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3387559_2	522772.Dacet_2940	1.333e-32	131.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.17	ko:K01518,ko:K08296	ko00230,ko00240,map00230,map00240	-	R00184,R00969,R01232,R02805	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
YHH1_k127_3387559_4	945713.IALB_3127	5.529e-17	86.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,FG-GAP,HYR,VCBS
YHH1_k127_3387559_3	880073.Calab_1046	4.646e-28	115.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
YHH1_k127_3430724_1	357808.RoseRS_1980	7.233e-57	203.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi,3777D@32061|Chloroflexia	32061|Chloroflexia	S	PFAM cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
YHH1_k127_3430724_0	518766.Rmar_2346	5.362e-68	238.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1FINM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
YHH1_k127_3430724_2	1203611.KB894541_gene1422	9.573e-05	49.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_3434382_0	526227.Mesil_1637	6.704e-117	385.0	COG2986@1|root,COG2986@2|Bacteria,1WISU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Phenylalanine and histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
YHH1_k127_3434382_1	530564.Psta_0808	1.462e-22	104.0	COG0517@1|root,COG0517@2|Bacteria,2J0MQ@203682|Planctomycetes	203682|Planctomycetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YHH1_k127_3436473_2	1296415.JACC01000011_gene543	1.334e-09	58.0	COG4104@1|root,COG4104@2|Bacteria,4NSCZ@976|Bacteroidetes,1I4Y4@117743|Flavobacteriia,2YM39@290174|Aquimarina	976|Bacteroidetes	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
YHH1_k127_3436473_1	1296416.JACB01000029_gene4198	1.038e-64	224.0	COG3628@1|root,COG3628@2|Bacteria,4NSKN@976|Bacteroidetes,1I48Y@117743|Flavobacteriia,2YJZ4@290174|Aquimarina	976|Bacteroidetes	S	Gene 25-like lysozyme	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
YHH1_k127_3436473_0	1296416.JACB01000029_gene4197	2.353e-258	835.0	COG3299@1|root,COG3299@2|Bacteria,4NF69@976|Bacteroidetes,1HYP7@117743|Flavobacteriia,2YIDG@290174|Aquimarina	976|Bacteroidetes	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
YHH1_k127_3443231_2	655815.ZPR_1222	8.197e-30	124.0	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,1I0Q1@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_3443231_3	1168034.FH5T_01410	1.851e-06	55.0	2EFPT@1|root,339FT@2|Bacteria,4NV1V@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3443231_1	945713.IALB_1460	2.604e-56	200.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	ko:K14061	-	-	-	-	ko00000	-	-	-	Usp
YHH1_k127_3443231_0	880073.Calab_1017	1.465e-143	492.0	COG3408@1|root,COG4945@1|root,COG3408@2|Bacteria,COG4945@2|Bacteria	2|Bacteria	G	C-terminal binding-module, SLH-like, of glucodextranase	VVA0055	-	3.2.1.3,3.2.1.41	ko:K01178,ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R01790,R01791,R02111,R06199	-	ko00000,ko00001,ko01000	-	CBM48,GH13,GH15	-	Alpha-amylase,Cu_amine_oxidN1,GDE_C,GDE_N,Glucodextran_B,Glucodextran_C,Glucodextran_N,Glyco_hydro_15,Glyco_hydro_49,Glyco_hydro_49N
YHH1_k127_3458014_2	459349.CLOAM1071	1.838e-61	232.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CARDB,Cadherin-like,DUF4091
YHH1_k127_3458014_1	665571.STHERM_c01980	8.916e-125	410.0	COG3842@1|root,COG3842@2|Bacteria,2J5T3@203691|Spirochaetes	203691|Spirochaetes	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
YHH1_k127_3458014_0	945713.IALB_1735	4.658e-201	633.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	malT	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
YHH1_k127_3458279_1	290399.Arth_0613	3.505e-81	277.0	COG2085@1|root,COG2085@2|Bacteria,2GMN3@201174|Actinobacteria	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
YHH1_k127_3458279_2	1121930.AQXG01000002_gene2236	2.367e-47	175.0	COG1522@1|root,COG1522@2|Bacteria,4NNMR@976|Bacteroidetes	976|Bacteroidetes	K	COG1522 Transcriptional regulators	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
YHH1_k127_3458279_0	945713.IALB_2718	4.177e-157	500.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YHH1_k127_3467405_3	518766.Rmar_0354	3.905e-13	81.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.62	ko:K01342,ko:K12287,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02044,ko03110	-	-	-	FG-GAP,PPC,Peptidase_C2,Peptidase_S8,VCBS
YHH1_k127_3467405_1	1121898.Q766_09985	7.594e-57	213.0	COG2931@1|root,COG2931@2|Bacteria,4P372@976|Bacteroidetes,1I9CV@117743|Flavobacteriia	976|Bacteroidetes	Q	C-type lectin (CTL) or carbohydrate-recognition domain (CRD)	-	-	-	-	-	-	-	-	-	-	-	-	Lectin_C
YHH1_k127_3467405_0	1121904.ARBP01000006_gene3738	6.348e-57	207.0	COG3279@1|root,COG3279@2|Bacteria,4NNIK@976|Bacteroidetes,47XE1@768503|Cytophagia	976|Bacteroidetes	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
YHH1_k127_3467405_2	1121957.ATVL01000010_gene573	3.634e-26	112.0	COG2972@1|root,COG2972@2|Bacteria,4NK1H@976|Bacteroidetes,47M46@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
YHH1_k127_3478570_0	1191523.MROS_0226	2.531e-92	308.0	COG0081@1|root,COG0081@2|Bacteria	2|Bacteria	J	regulation of translation	rplA	GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
YHH1_k127_3478570_1	945713.IALB_0901	9.913e-69	235.0	COG0080@1|root,COG0080@2|Bacteria	2|Bacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
YHH1_k127_3478570_2	1191523.MROS_0228	8.287e-61	220.0	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
YHH1_k127_3478570_4	1191523.MROS_0229	1.688e-11	68.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
YHH1_k127_3478570_3	945713.IALB_0898	2.711e-16	79.0	COG0267@1|root,COG0267@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
YHH1_k127_3526420_0	530564.Psta_4193	4.681e-214	681.0	COG0433@1|root,COG0433@2|Bacteria,2IY71@203682|Planctomycetes	203682|Planctomycetes	L	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87,PDDEXK_1
YHH1_k127_3556833_0	118166.JH976538_gene5194	8.905e-37	157.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H7GW@1150|Oscillatoriales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
YHH1_k127_3556833_1	945713.IALB_1926	5.375e-30	132.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
YHH1_k127_3558136_1	316275.VSAL_I1765	5.315e-10	70.0	COG0671@1|root,COG0671@2|Bacteria,1N3TP@1224|Proteobacteria,1SADV@1236|Gammaproteobacteria,1Y2AB@135623|Vibrionales	135623|Vibrionales	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YHH1_k127_3558136_0	1191523.MROS_1272	9.934e-35	147.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH,LTD
YHH1_k127_356286_0	1191523.MROS_1530	8.131e-144	469.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
YHH1_k127_356286_1	382464.ABSI01000011_gene2775	1.315e-74	261.0	COG0488@1|root,COG0488@2|Bacteria,46V06@74201|Verrucomicrobia,2IU2D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH1_k127_3573080_0	1237149.C900_03131	6.574e-42	168.0	COG2353@1|root,COG2353@2|Bacteria,4NUV8@976|Bacteroidetes,47UW8@768503|Cytophagia	1237149.C900_03131|-	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3573080_1	929556.Solca_0737	2.233e-22	104.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IR0W@117747|Sphingobacteriia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA
YHH1_k127_3586973_0	1519464.HY22_13055	6.851e-97	339.0	COG0265@1|root,COG0366@1|root,COG0265@2|Bacteria,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Alpha-amylase
YHH1_k127_3591016_0	945713.IALB_1856	1.571e-120	391.0	COG0504@1|root,COG0504@2|Bacteria	2|Bacteria	F	CTP synthase activity	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377	CTP_synth_N,GATase
YHH1_k127_3591016_2	1191523.MROS_1632	3.344e-57	211.0	COG4589@1|root,COG4589@2|Bacteria	2|Bacteria	S	phosphatidate cytidylyltransferase activity	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
YHH1_k127_3591016_4	945713.IALB_0621	2.8e-07	59.0	COG2260@1|root,COG2260@2|Bacteria	2|Bacteria	J	snoRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
YHH1_k127_3591016_3	1191523.MROS_1630	3.886e-29	130.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YHH1_k127_3591016_1	352165.HMPREF7215_0319	2.261e-83	284.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3595942_2	1379698.RBG1_1C00001G0183	3.532e-42	179.0	COG4447@1|root,COG4447@2|Bacteria,2NRC1@2323|unclassified Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_3595942_1	479434.Sthe_3025	1.162e-51	199.0	COG1169@1|root,COG1169@2|Bacteria,2GADW@200795|Chloroflexi,27Y2P@189775|Thermomicrobia	189775|Thermomicrobia	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
YHH1_k127_3595942_0	797209.ZOD2009_07799	1.328e-73	263.0	COG1165@1|root,arCOG04611@2157|Archaea,2XUM8@28890|Euryarchaeota,23TJ0@183963|Halobacteria	183963|Halobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
YHH1_k127_3600812_1	582515.KR51_00034910	1.1e-35	149.0	COG0354@1|root,COG0354@2|Bacteria,1G0RW@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the GcvT family	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
YHH1_k127_3600812_0	945713.IALB_1617	4.603e-98	332.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	ko:K00226,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15540	DHO_dh
YHH1_k127_3600812_2	945713.IALB_1618	1.497e-15	77.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	pyrK	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0042602,GO:0052875,GO:0055114	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
YHH1_k127_36201_0	264462.Bd1227	2.915e-174	566.0	COG1175@1|root,COG2182@1|root,COG1175@2|Bacteria,COG2182@2|Bacteria,1MXKR@1224|Proteobacteria,42UM4@68525|delta/epsilon subdivisions,2MTUJ@213481|Bdellovibrionales,2WQPJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	Sugar ABC transporter permease	malF	-	-	ko:K10109,ko:K15770,ko:K15771	ko02010,map02010	M00194,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	-	BPD_transp_1,SBP_bac_8
YHH1_k127_3627861_1	1191523.MROS_2717	1.871e-31	128.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
YHH1_k127_3627861_3	1313421.JHBV01000039_gene2629	0.0001344	55.0	2F1WD@1|root,33UW2@2|Bacteria,4P2AY@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3627861_0	945713.IALB_1260	8.315e-50	186.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
YHH1_k127_3627861_2	1122137.AQXF01000001_gene3014	1.509e-07	61.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2TRVS@28211|Alphaproteobacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,CBM_48
YHH1_k127_364593_0	1191523.MROS_2079	2.174e-20	103.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
YHH1_k127_365269_0	7739.XP_002590051.1	1.56e-30	139.0	COG2373@1|root,KOG1216@1|root,KOG4297@1|root,KOG1216@2759|Eukaryota,KOG1366@2759|Eukaryota,KOG4297@2759|Eukaryota,38BA2@33154|Opisthokonta,3BHBM@33208|Metazoa,3CSSV@33213|Bilateria,4802J@7711|Chordata	33208|Metazoa	VW	binding of sperm to zona pellucida	ZAN	-	-	-	-	-	-	-	-	-	-	-	C8,EGF,IgGFc_binding,Lectin_C,MAM,TIL,TILa,VWD
YHH1_k127_367773_0	945713.IALB_1789	3.875e-06	60.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_367773_1	518766.Rmar_0295	0.0001551	51.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH1_k127_3679491_1	404380.Gbem_1699	9.649e-20	95.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,42QFG@68525|delta/epsilon subdivisions,2WK91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YHH1_k127_3679491_0	714943.Mucpa_7166	8.136e-34	145.0	COG2885@1|root,COG2885@2|Bacteria,4NI1Y@976|Bacteroidetes,1IQRR@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2,OmpA
YHH1_k127_3686880_0	37659.JNLN01000001_gene1752	5.184e-51	191.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,36E8U@31979|Clostridiaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
YHH1_k127_3686880_1	521003.COLINT_03757	1.626e-29	129.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4CVMI@84998|Coriobacteriia	84998|Coriobacteriia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
YHH1_k127_3699967_1	945713.IALB_1372	1.112e-27	123.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y
YHH1_k127_3699967_0	945713.IALB_1373	4.151e-202	650.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	treP	-	-	ko:K07126,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,PD40,POTRA
YHH1_k127_3705288_2	1191523.MROS_2379	9.283e-46	169.0	COG0838@1|root,COG0838@2|Bacteria	2|Bacteria	C	NADH dehydrogenase (ubiquinone) activity	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330,ko:K05574	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YHH1_k127_3705288_1	945713.IALB_1623	3.18e-82	275.0	COG0377@1|root,COG0377@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YHH1_k127_3705288_3	517418.Ctha_2563	1.197e-44	168.0	COG0852@1|root,COG0852@2|Bacteria,1FDXF@1090|Chlorobi	1090|Chlorobi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
YHH1_k127_3705288_0	1191523.MROS_2376	4.095e-186	588.0	COG0649@1|root,COG0649@2|Bacteria	2|Bacteria	C	NAD binding	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
YHH1_k127_3705288_4	290512.Paes_0846	2.503e-15	78.0	COG1005@1|root,COG1005@2|Bacteria,1FDP9@1090|Chlorobi	1090|Chlorobi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH1_k127_3706465_2	1191523.MROS_2697	8.649e-34	138.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
YHH1_k127_3706465_1	945713.IALB_1484	2.886e-103	348.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH1_k127_3706465_0	635013.TherJR_0825	2.051e-175	559.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,260RX@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
YHH1_k127_3743057_0	925409.KI911562_gene168	4.165e-27	127.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1IW9T@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
YHH1_k127_3751261_0	945713.IALB_0720	4.538e-256	813.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
YHH1_k127_3751261_1	1519464.HY22_05025	1.256e-23	104.0	COG4531@1|root,COG4531@2|Bacteria	2|Bacteria	P	zinc ion transport	actF	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3757332_0	945713.IALB_2200	1.188e-98	331.0	COG0206@1|root,COG0206@2|Bacteria	2|Bacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YHH1_k127_3759821_0	411476.BACOVA_01943	4.354e-72	251.0	COG1213@1|root,COG1213@2|Bacteria,4NF7V@976|Bacteroidetes,2G339@200643|Bacteroidia,4AW90@815|Bacteroidaceae	976|Bacteroidetes	M	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
YHH1_k127_3759821_2	1353529.M899_2215	2.694e-26	121.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.34	ko:K07291	ko00562,map00562	-	R09670	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YHH1_k127_3759821_1	1121129.KB903367_gene2718	2.645e-61	218.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,2FMKS@200643|Bacteroidia,22XH3@171551|Porphyromonadaceae	976|Bacteroidetes	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_3776475_1	945713.IALB_1054	1.167e-21	96.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3776475_0	518766.Rmar_0603	1.897e-52	198.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1FJJN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YHH1_k127_3778780_0	383372.Rcas_0577	2.169e-19	103.0	COG0515@1|root,COG0515@2|Bacteria	383372.Rcas_0577|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
YHH1_k127_3787018_0	945713.IALB_0460	7.684e-201	635.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria	2|Bacteria	J	methionyl-tRNA aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10,6.1.1.20	ko:K01874,ko:K01890,ko:K06878	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R03660,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446	Anticodon_1,tRNA-synt_1g,tRNA_bind
YHH1_k127_3789572_1	111780.Sta7437_1577	7.44e-10	70.0	COG1943@1|root,COG1943@2|Bacteria,1G79U@1117|Cyanobacteria,3VK18@52604|Pleurocapsales	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_3789572_0	1501391.LG35_05415	5.21e-64	228.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,2FM9T@200643|Bacteroidia,22U3K@171550|Rikenellaceae	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YHH1_k127_380430_1	1223410.KN050846_gene205	5.749e-23	102.0	2DCFR@1|root,2ZDYQ@2|Bacteria,4NPNX@976|Bacteroidetes,1I27F@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
YHH1_k127_380430_0	1191523.MROS_2846	5.142e-113	374.0	COG0280@1|root,COG0280@2|Bacteria	2|Bacteria	C	phosphate acetyltransferase	pta	-	1.1.1.40,2.3.1.8	ko:K00029,ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00172,M00357,M00579	R00216,R00230,R00921	RC00004,RC00105,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
YHH1_k127_380430_2	946077.W5A_02780	2.356e-20	96.0	COG0084@1|root,COG0084@2|Bacteria,4NSGW@976|Bacteroidetes,1I2AW@117743|Flavobacteriia	976|Bacteroidetes	L	hydrolase, TatD	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YHH1_k127_3808177_1	557599.MKAN_23875	3.985e-75	260.0	COG0438@1|root,COG0438@2|Bacteria,2IPY0@201174|Actinobacteria,23D08@1762|Mycobacteriaceae	201174|Actinobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
YHH1_k127_3808177_0	197221.22296114	2.807e-153	488.0	COG1216@1|root,COG1216@2|Bacteria,1G2TX@1117|Cyanobacteria	1117|Cyanobacteria	Q	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3833010_1	1048983.EL17_07115	0.0001155	49.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47K6G@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_3863545_0	794903.OPIT5_07155	4.158e-77	269.0	COG1101@1|root,COG1101@2|Bacteria,46YSY@74201|Verrucomicrobia,3K9UK@414999|Opitutae	414999|Opitutae	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
YHH1_k127_3863545_1	794903.OPIT5_07150	1.191e-37	151.0	COG4120@1|root,COG4120@2|Bacteria,46YK2@74201|Verrucomicrobia,3K9RK@414999|Opitutae	414999|Opitutae	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
YHH1_k127_3883101_2	945713.IALB_2366	5.913e-23	104.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
YHH1_k127_3883101_0	1120973.AQXL01000129_gene2425	2.175e-236	739.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,4HA3C@91061|Bacilli,27ASA@186823|Alicyclobacillaceae	91061|Bacilli	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
YHH1_k127_3883101_1	1121129.KB903360_gene3193	6.109e-67	233.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,2FSBJ@200643|Bacteroidia,22Y1Y@171551|Porphyromonadaceae	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
YHH1_k127_3898500_0	643867.Ftrac_1561	1.36e-123	413.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47MDX@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_3912844_0	1123277.KB893185_gene3019	3.126e-05	58.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,47Y22@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
YHH1_k127_391671_1	1519464.HY22_04465	8.595e-18	85.0	COG1595@1|root,COG1595@2|Bacteria,1FE7H@1090|Chlorobi	1090|Chlorobi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_391671_3	697281.Mahau_1176	0.0005883	50.0	COG5662@1|root,COG5662@2|Bacteria,1UHWV@1239|Firmicutes,24JF8@186801|Clostridia,42GU0@68295|Thermoanaerobacterales	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
YHH1_k127_391671_2	1484460.JSWG01000009_gene644	9.663e-16	79.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,4NFEW@976|Bacteroidetes,1HZIS@117743|Flavobacteriia	976|Bacteroidetes	E	Dehydrogenase	-	-	-	ko:K02030,ko:K03810	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	ADH_zinc_N,GFO_IDH_MocA
YHH1_k127_3928144_1	909663.KI867150_gene400	4.861e-116	376.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MR61@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, NADH-binding	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
YHH1_k127_3928144_2	909663.KI867150_gene400	4.235e-73	250.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MR61@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, NADH-binding	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
YHH1_k127_3928144_0	909663.KI867150_gene399	2.611e-145	479.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MR16@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase, Fe4S4	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
YHH1_k127_3932726_0	1089548.KI783301_gene2258	2.953e-55	200.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,3WE4M@539002|Bacillales incertae sedis	91061|Bacilli	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
YHH1_k127_3932726_2	999419.HMPREF1077_01007	1.298e-17	91.0	2DNG4@1|root,32XBP@2|Bacteria,4NUAE@976|Bacteroidetes,2FTVS@200643|Bacteroidia,22ZMR@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3932726_1	1519464.HY22_03695	4.987e-42	166.0	COG0760@1|root,COG0760@2|Bacteria,1FEUV@1090|Chlorobi	1090|Chlorobi	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	-
YHH1_k127_3932726_3	1123392.AQWL01000005_gene3109	1.941e-16	78.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,1KRC1@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
YHH1_k127_3948120_2	102232.GLO73106DRAFT_00004740	1.766e-08	57.0	COG1917@1|root,COG1917@2|Bacteria,1GE8U@1117|Cyanobacteria	1117|Cyanobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3948120_0	700598.Niako_5053	9.706e-74	275.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_3948120_1	945713.IALB_2314	9.23e-66	251.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_3948120_3	688245.CtCNB1_0723	4.816e-08	58.0	COG5298@1|root,COG5298@2|Bacteria,1MYMJ@1224|Proteobacteria,2VPZF@28216|Betaproteobacteria,4AHGX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2334)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334
YHH1_k127_3978488_0	234267.Acid_4295	9.383e-119	393.0	COG2208@1|root,COG4753@1|root,COG2208@2|Bacteria,COG4753@2|Bacteria,3Y6AE@57723|Acidobacteria	57723|Acidobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
YHH1_k127_3978488_1	1304874.JAFY01000001_gene2556	1.565e-45	175.0	COG2984@1|root,COG2984@2|Bacteria,3TBSS@508458|Synergistetes	508458|Synergistetes	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
YHH1_k127_3978488_2	794903.OPIT5_07145	3.546e-13	75.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS,STAS_2
YHH1_k127_4002660_1	153721.MYP_4620	2.692e-07	60.0	2EKCZ@1|root,33E39@2|Bacteria,4NXWT@976|Bacteroidetes,47VYQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4002660_0	1191523.MROS_0477	4.199e-71	248.0	COG2352@1|root,COG2352@2|Bacteria	2|Bacteria	C	phosphoenolpyruvate carboxylase activity	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.ppc,iSFV_1184.SFV_4025	PEPcase
YHH1_k127_4022721_0	926566.Terro_3399	1.177e-19	103.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YHH1_k127_4022721_1	983544.Lacal_1835	5.976e-13	77.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
YHH1_k127_4028775_0	880073.Calab_1892	6.159e-70	251.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
YHH1_k127_4028775_1	945713.IALB_0828	7.268e-38	146.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	btrV	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
YHH1_k127_4028775_2	945713.IALB_0829	1.467e-31	134.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
YHH1_k127_4035042_2	1121448.DGI_0173	3.139e-06	61.0	2E0M7@1|root,32W6F@2|Bacteria,1NB9Z@1224|Proteobacteria,42W6T@68525|delta/epsilon subdivisions,2WSFF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4035042_0	886293.Sinac_7534	1.128e-62	242.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4035042_1	1121405.dsmv_0278	3.97e-54	197.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,42MTT@68525|delta/epsilon subdivisions,2WJAP@28221|Deltaproteobacteria,2MI6M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
YHH1_k127_405274_0	945713.IALB_0586	4.465e-139	460.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
YHH1_k127_4057055_3	1379270.AUXF01000004_gene3060	1.238e-70	254.0	COG3367@1|root,COG3367@2|Bacteria,1ZUM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
YHH1_k127_4057055_0	1191523.MROS_1853	2.216e-170	546.0	COG0104@1|root,COG0104@2|Bacteria	2|Bacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
YHH1_k127_4057055_4	1121104.AQXH01000001_gene1809	5.096e-29	119.0	COG1366@1|root,COG1366@2|Bacteria,4NTNE@976|Bacteroidetes	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YHH1_k127_4057055_2	945713.IALB_0834	6.572e-88	299.0	COG0341@1|root,COG0341@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YHH1_k127_4057055_1	518766.Rmar_1455	1.272e-150	497.0	COG0342@1|root,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1FIW5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YHH1_k127_4058879_1	309807.SRU_2571	3.223e-13	70.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1FIMG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
YHH1_k127_4058879_0	1191523.MROS_1780	1.027e-113	385.0	COG2366@1|root,COG2366@2|Bacteria	2|Bacteria	D	antibiotic biosynthetic process	acyII	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
YHH1_k127_4061769_0	1296416.JACB01000029_gene4193	8.166e-274	864.0	COG5412@1|root,COG5412@2|Bacteria,4NJXH@976|Bacteroidetes,1HYSA@117743|Flavobacteriia,2YHCW@290174|Aquimarina	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Endonuclea_NS_2
YHH1_k127_4065039_0	926549.KI421517_gene2870	1.149e-200	632.0	COG4147@1|root,COG4147@2|Bacteria,4NHPT@976|Bacteroidetes,47JSK@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
YHH1_k127_4065039_2	926549.KI421517_gene2871	1.901e-26	113.0	COG3162@1|root,COG3162@2|Bacteria	2|Bacteria	S	Protein of unknown function, DUF485	yjcH	-	-	-	-	-	-	-	-	-	-	-	DUF485
YHH1_k127_4065039_1	1304885.AUEY01000007_gene1357	2.446e-84	290.0	COG2202@1|root,COG2905@1|root,COG4564@1|root,COG2202@2|Bacteria,COG2905@2|Bacteria,COG4564@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2WJF5@28221|Deltaproteobacteria,2MIA9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,PAS_8,cNMP_binding,sCache_2
YHH1_k127_4071078_4	1906.SFRA_06330	9.524e-07	59.0	COG4447@1|root,COG4447@2|Bacteria,2GJF7@201174|Actinobacteria	201174|Actinobacteria	G	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,fn3
YHH1_k127_4071078_0	443143.GM18_2753	4.764e-64	233.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42TZR@68525|delta/epsilon subdivisions,2WQAW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH1_k127_4071078_2	1379698.RBG1_1C00001G0055	7.487e-20	100.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
YHH1_k127_4071078_3	945713.IALB_2177	1.998e-19	98.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YHH1_k127_4071078_1	1313301.AUGC01000003_gene2121	3.359e-30	124.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
YHH1_k127_4079742_0	204669.Acid345_0471	1.53e-125	426.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4079742_5	682795.AciX8_1654	5.015e-24	107.0	COG0494@1|root,COG0494@2|Bacteria,3Y55X@57723|Acidobacteria,2JN43@204432|Acidobacteriia	204432|Acidobacteriia	L	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YHH1_k127_4079742_1	479434.Sthe_3260	2.674e-60	220.0	COG1194@1|root,COG1194@2|Bacteria,2G62P@200795|Chloroflexi,27XJQ@189775|Thermomicrobia	189775|Thermomicrobia	L	FES	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YHH1_k127_4079742_4	439481.Aboo_0474	3.075e-31	131.0	COG1059@1|root,arCOG04357@2157|Archaea,2XWSZ@28890|Euryarchaeota,3F2WU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)	ogg	-	4.2.99.18	ko:K03653	-	-	-	-	ko00000,ko01000	-	-	-	-
YHH1_k127_4079742_2	309800.C498_13183	1.137e-57	211.0	COG1120@1|root,arCOG00199@2157|Archaea,2XTTV@28890|Euryarchaeota,23SRW@183963|Halobacteria	183963|Halobacteria	E	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	btuD	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
YHH1_k127_4079742_3	1191523.MROS_0126	2.016e-36	148.0	COG0781@1|root,COG0781@2|Bacteria	2|Bacteria	J	transcription antitermination	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
YHH1_k127_4079742_6	1120950.KB892757_gene6517	4.477e-08	57.0	COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria,4DNKE@85009|Propionibacteriales	201174|Actinobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
YHH1_k127_4090251_2	1089545.KB913037_gene7600	5.649e-20	104.0	COG0611@1|root,COG0611@2|Bacteria,2I8EE@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	-	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH1_k127_4090251_1	1206737.BAGF01000075_gene4763	9.916e-42	167.0	COG1597@1|root,COG1597@2|Bacteria,2HHKU@201174|Actinobacteria,4FZ0T@85025|Nocardiaceae	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
YHH1_k127_4090251_0	714943.Mucpa_6877	1.718e-56	210.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39,2.5.1.42	ko:K03179,ko:K17105	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00117	R04520,R05000,R05615	RC00209,RC01171,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
YHH1_k127_4111664_0	756272.Plabr_1583	1.366e-187	597.0	COG1271@1|root,COG1271@2|Bacteria,2IXYC@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome bd-type quinol oxidase subunit 1	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
YHH1_k127_4111664_1	517418.Ctha_0930	2.997e-129	423.0	COG1294@1|root,COG1294@2|Bacteria,1FDE9@1090|Chlorobi	1090|Chlorobi	C	Cytochrome d ubiquinol oxidase, subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
YHH1_k127_4111740_0	880073.Calab_1383	1.117e-99	341.0	COG1200@1|root,COG1200@2|Bacteria,2NNS3@2323|unclassified Bacteria	2|Bacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YHH1_k127_4116297_0	146922.JOFU01000072_gene7993	1.111e-32	147.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknA	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
YHH1_k127_412398_0	517418.Ctha_1565	6.312e-117	386.0	COG4608@1|root,COG4608@2|Bacteria,1FDGY@1090|Chlorobi	1090|Chlorobi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
YHH1_k127_412398_1	1121104.AQXH01000001_gene1931	1.485e-42	166.0	COG1355@1|root,COG1355@2|Bacteria	2|Bacteria	C	regulation of microtubule-based process	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
YHH1_k127_4133346_0	945713.IALB_2642	2.549e-146	471.0	COG0172@1|root,COG0172@2|Bacteria	2|Bacteria	J	seryl-tRNA aminoacylation	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YHH1_k127_4133346_1	1519464.HY22_13630	1.778e-72	259.0	COG1091@1|root,COG1091@2|Bacteria,1FD6G@1090|Chlorobi	1090|Chlorobi	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
YHH1_k127_4133346_2	1265310.CCBD010000007_gene3233	1.104e-09	69.0	COG0524@1|root,COG0524@2|Bacteria,2GP1C@201174|Actinobacteria,237N3@1762|Mycobacteriaceae	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH1_k127_4139334_3	861299.J421_3564	3.957e-57	207.0	COG2003@1|root,COG2003@2|Bacteria,1ZTFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
YHH1_k127_4139334_1	700598.Niako_6329	4.156e-106	349.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1IRDU@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH1_k127_4139334_0	880073.Calab_1133	3.715e-110	371.0	COG1030@1|root,COG1030@2|Bacteria,2NNMU@2323|unclassified Bacteria	2|Bacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
YHH1_k127_4139334_2	234267.Acid_0921	1.58e-88	302.0	COG3581@1|root,COG3581@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4142351_2	402880.MmarC5_0829	1.613e-10	74.0	COG3291@1|root,arCOG03396@2157|Archaea	2157|Archaea	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	A2M_comp,CARDB,Prenyltrans,SQHop_cyclase_C,Thiol-ester_cl
YHH1_k127_4142351_1	880073.Calab_3451	4.474e-13	82.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane
YHH1_k127_4142351_0	1242864.D187_005397	2.706e-32	136.0	2DB8Y@1|root,2Z7TF@2|Bacteria,1NCMY@1224|Proteobacteria,43B9S@68525|delta/epsilon subdivisions,2X6NX@28221|Deltaproteobacteria,2Z3BY@29|Myxococcales	1224|Proteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
YHH1_k127_415039_0	945713.IALB_1148	5.783e-180	567.0	COG2079@1|root,COG2079@2|Bacteria	2|Bacteria	S	2-methylcitrate dehydratase activity	prpD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
YHH1_k127_415039_1	1122931.AUAE01000016_gene2723	9.72e-38	155.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia,22W84@171551|Porphyromonadaceae	976|Bacteroidetes	T	histidine kinase DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
YHH1_k127_415194_1	945713.IALB_0633	1.076e-70	250.0	COG1127@1|root,COG1127@2|Bacteria	2|Bacteria	Q	ATPase activity	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YHH1_k127_415194_0	945713.IALB_0632	2.437e-84	288.0	COG0767@1|root,COG0767@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YHH1_k127_415194_3	324925.Ppha_2903	0.0001627	51.0	COG3688@1|root,COG3688@2|Bacteria,1FECC@1090|Chlorobi	1090|Chlorobi	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
YHH1_k127_415194_2	1117379.BABA_18477	1.324e-11	64.0	COG3185@1|root,COG3185@2|Bacteria,1UZP2@1239|Firmicutes,4HDQI@91061|Bacilli,1ZEQ2@1386|Bacillus	91061|Bacilli	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
YHH1_k127_4169606_1	518766.Rmar_0314	4.563e-18	88.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1FJFS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
YHH1_k127_4169606_0	945713.IALB_0772	4.681e-196	616.0	COG0056@1|root,COG0056@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
YHH1_k127_4177177_0	1121403.AUCV01000005_gene357	3.496e-21	106.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF,HAMP,PAS,PAS_3
YHH1_k127_4177177_1	880073.Calab_0525	2.045e-08	55.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YHH1_k127_4207145_2	234267.Acid_0921	2.478e-50	192.0	COG3581@1|root,COG3581@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4207145_3	1278073.MYSTI_03664	6.011e-26	117.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42RRD@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	L,D-transpeptidase catalytic domain	yafK	-	-	-	-	-	-	-	-	-	-	-	YkuD
YHH1_k127_4207145_4	264198.Reut_B3970	3.568e-20	104.0	COG1538@1|root,COG1538@2|Bacteria,1RFMJ@1224|Proteobacteria,2W2GG@28216|Betaproteobacteria,1K5MV@119060|Burkholderiaceae	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
YHH1_k127_4207145_1	1379270.AUXF01000001_gene2702	3.273e-63	241.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
YHH1_k127_4207145_0	1089550.ATTH01000001_gene2034	0.0	1108.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1FJVI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
YHH1_k127_4216354_1	330214.NIDE0870	7.696e-64	220.0	COG0821@1|root,COG0821@2|Bacteria,3J0EA@40117|Nitrospirae	40117|Nitrospirae	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
YHH1_k127_4216354_0	330214.NIDE0891	7.076e-207	645.0	COG0535@1|root,COG0535@2|Bacteria,3J0X6@40117|Nitrospirae	40117|Nitrospirae	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
YHH1_k127_4216354_2	330214.NIDE0892	2.488e-42	159.0	29E6W@1|root,3014W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4217128_0	1197130.BAFM01000012_gene2204	3.647e-10	72.0	arCOG02903@1|root,arCOG03612@1|root,arCOG02903@2157|Archaea,arCOG03612@2157|Archaea	2157|Archaea	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Big_1,DUF1573,PKD,VWA
YHH1_k127_4218918_1	243231.GSU2317	1.487e-79	274.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,43S4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
YHH1_k127_4218918_0	1296416.JACB01000029_gene4190	8.753e-159	513.0	COG0464@1|root,COG0464@2|Bacteria,4NFWG@976|Bacteroidetes,1HZA4@117743|Flavobacteriia,2YI1T@290174|Aquimarina	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
YHH1_k127_4218918_2	1296416.JACB01000029_gene4191	1.261e-11	65.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4239332_1	869210.Marky_0563	1.77e-30	130.0	COG1011@1|root,COG1011@2|Bacteria,1WI88@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
YHH1_k127_4239332_0	945713.IALB_2639	9.672e-88	302.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	mdlA	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH1_k127_424649_1	983917.RGE_06320	1.887e-65	227.0	COG1670@1|root,COG1670@2|Bacteria,1QUWE@1224|Proteobacteria	1224|Proteobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_424649_2	1122927.KB895415_gene4386	2.079e-11	68.0	2C95S@1|root,33HPC@2|Bacteria,1VJZ1@1239|Firmicutes,4I8KU@91061|Bacilli,2703Y@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
YHH1_k127_424649_0	1124780.ANNU01000017_gene1934	2.34e-87	293.0	COG2120@1|root,COG2120@2|Bacteria,4NMM2@976|Bacteroidetes,47WAX@768503|Cytophagia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YHH1_k127_4255218_0	272123.Anacy_1194	1.61e-21	110.0	COG0834@1|root,COG2931@1|root,COG0834@2|Bacteria,COG2931@2|Bacteria,1G2N0@1117|Cyanobacteria	1117|Cyanobacteria	Q	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,DUF4114,DUF4347,HemolysinCabind,Laminin_G_3,SBP_bac_3,VCBS
YHH1_k127_4255218_1	945713.IALB_0884	1.429e-18	98.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_4255218_2	880073.Calab_2214	1.024e-14	78.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	-
YHH1_k127_4262021_0	1403819.BATR01000133_gene4715	2.543e-10	74.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Exo_endo_phos,F5_F8_type_C,Laminin_G_3
YHH1_k127_426530_2	226185.EF_1738	0.0006089	44.0	COG4430@1|root,COG4430@2|Bacteria,1V41W@1239|Firmicutes,4HDKN@91061|Bacilli,4B0A1@81852|Enterococcaceae	91061|Bacilli	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
YHH1_k127_426530_0	1163409.UUA_13987	1.183e-216	685.0	COG1075@1|root,COG1075@2|Bacteria,1MXMP@1224|Proteobacteria,1RYZM@1236|Gammaproteobacteria,1X44F@135614|Xanthomonadales	135614|Xanthomonadales	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
YHH1_k127_426530_1	316067.Geob_3194	2.331e-19	89.0	COG3409@1|root,COG3409@2|Bacteria,1QYWY@1224|Proteobacteria	1224|Proteobacteria	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,PG_binding_1
YHH1_k127_4276639_1	1207063.P24_01305	6.059e-75	264.0	COG2267@1|root,COG2267@2|Bacteria,1NK3M@1224|Proteobacteria,2TRP8@28211|Alphaproteobacteria,2JS7D@204441|Rhodospirillales	204441|Rhodospirillales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
YHH1_k127_4276639_2	1379270.AUXF01000001_gene2260	1.484e-53	193.0	COG2318@1|root,COG2318@2|Bacteria,1ZUV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YHH1_k127_4276639_0	1185876.BN8_06034	5.769e-84	290.0	COG4826@1|root,COG4826@2|Bacteria,4NG1G@976|Bacteroidetes,47N0P@768503|Cytophagia	976|Bacteroidetes	O	proteinase inhibitor I4 serpin	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
YHH1_k127_4285783_1	945713.IALB_2863	1.194e-20	108.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	CARDB,FTP,He_PIG,PA,Peptidase_M30,Peptidase_M36,Peptidase_M6
YHH1_k127_4285783_0	1122128.AUEE01000004_gene288	1.629e-37	143.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,4GXJI@90964|Staphylococcaceae	91061|Bacilli	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11010	UPRTase
YHH1_k127_4289135_0	945713.IALB_0538	5.94e-192	611.0	COG0635@1|root,COG0635@2|Bacteria	2|Bacteria	H	coproporphyrinogen oxidase activity	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.98.3	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R06895	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403	HemN_C,Radical_SAM
YHH1_k127_4289135_1	517418.Ctha_0924	1.656e-126	413.0	COG0407@1|root,COG0407@2|Bacteria,1FDJ2@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH1_k127_4289135_3	56780.SYN_02272	2.269e-17	91.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2MQX4@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
YHH1_k127_4289135_2	401526.TcarDRAFT_0742	1.206e-83	285.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H1XA@909932|Negativicutes	909932|Negativicutes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
YHH1_k127_4297126_0	1346791.M529_12395	9.339e-44	179.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,2VFU8@28211|Alphaproteobacteria,2K77J@204457|Sphingomonadales	204457|Sphingomonadales	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YHH1_k127_4311972_0	517418.Ctha_0038	5.278e-93	332.0	COG5617@1|root,COG5617@2|Bacteria,1FDV6@1090|Chlorobi	1090|Chlorobi	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
YHH1_k127_4311972_1	1173027.Mic7113_5740	2.539e-77	273.0	COG0438@1|root,COG0438@2|Bacteria,1G2XD@1117|Cyanobacteria,1HEGW@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_4311972_2	485915.Dret_0382	8.618e-06	52.0	COG2244@1|root,COG2244@2|Bacteria,1RHFX@1224|Proteobacteria,42TXE@68525|delta/epsilon subdivisions,2WTA9@28221|Deltaproteobacteria,2ME7N@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
YHH1_k127_4315220_0	880073.Calab_3685	4.615e-204	640.0	COG0473@1|root,COG0473@2|Bacteria,2NNUM@2323|unclassified Bacteria	2|Bacteria	CE	Isocitrate/isopropylmalate dehydrogenase	dlpA	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh,MoCF_biosynth,RraA-like
YHH1_k127_4315220_1	1121413.JMKT01000009_gene2016	6.701e-23	106.0	COG5012@1|root,COG5012@2|Bacteria,1RE0V@1224|Proteobacteria,42VZ0@68525|delta/epsilon subdivisions,2WRFJ@28221|Deltaproteobacteria,2MBN9@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Cobalamin B12-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
YHH1_k127_4337233_3	1121930.AQXG01000005_gene613	9.486e-11	75.0	COG1520@1|root,COG2706@1|root,COG2911@1|root,COG1520@2|Bacteria,COG2706@2|Bacteria,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	3.1.3.1	ko:K01113,ko:K20274	ko00790,ko01100,ko02020,ko02024,map00790,map01100,map02020,map02024	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	CHU_C,Laminin_G_3,SBBP,VCBS
YHH1_k127_4337233_0	1121406.JAEX01000001_gene415	1.966e-112	372.0	COG1215@1|root,COG1215@2|Bacteria,1R988@1224|Proteobacteria,42QGX@68525|delta/epsilon subdivisions,2WJPU@28221|Deltaproteobacteria,2M8JN@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_4337233_1	1499967.BAYZ01000007_gene5398	2.771e-50	190.0	COG0697@1|root,COG0697@2|Bacteria,2NRZ5@2323|unclassified Bacteria	2|Bacteria	EG	spore germination	Z012_05125	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_4337233_2	1121004.ATVC01000013_gene2055	3.815e-16	79.0	COG0824@1|root,COG0824@2|Bacteria,1RF7Q@1224|Proteobacteria,2VR5T@28216|Betaproteobacteria,2KRGT@206351|Neisseriales	206351|Neisseriales	S	thioesterase K01075	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
YHH1_k127_4348234_0	945713.IALB_2784	1.536e-25	118.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	cpt	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6
YHH1_k127_4348234_1	1353537.TP2_00585	0.0002307	51.0	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG4625@1|root,COG4935@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria,COG4935@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,DUF4214,HemolysinCabind,Hint_2
YHH1_k127_4350447_1	945713.IALB_2955	3.373e-97	331.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
YHH1_k127_4350447_2	1089553.Tph_c28850	1.621e-68	251.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,42H8N@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM TrkA-N domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
YHH1_k127_4350447_0	485915.Dret_1969	7.779e-128	426.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria,2M8CP@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
YHH1_k127_4350938_0	215803.DB30_3407	1.115e-96	334.0	COG3540@1|root,COG3540@2|Bacteria,1NWMQ@1224|Proteobacteria,4382N@68525|delta/epsilon subdivisions,2X3CQ@28221|Deltaproteobacteria,2YVFX@29|Myxococcales	28221|Deltaproteobacteria	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4350938_1	1537715.JQFJ01000002_gene1004	2.1e-74	269.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,2U3F9@28211|Alphaproteobacteria,2K2U7@204457|Sphingomonadales	204457|Sphingomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
YHH1_k127_4350938_2	117187.FVEG_01654T0	3.738e-61	225.0	COG0277@1|root,KOG4730@2759|Eukaryota,39SMZ@33154|Opisthokonta,3P0QT@4751|Fungi,3QRB3@4890|Ascomycota,21DZ2@147550|Sordariomycetes,3TRDQ@5125|Hypocreales,1FXCD@110618|Nectriaceae	4751|Fungi	V	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
YHH1_k127_4356583_1	1303518.CCALI_00437	2.594e-14	82.0	COG0457@1|root,COG0457@2|Bacteria	1303518.CCALI_00437|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4356583_0	929556.Solca_1759	5.219e-19	91.0	2EM7W@1|root,33EX0@2|Bacteria,4P5SH@976|Bacteroidetes,1J02V@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4356583_3	309807.SRU_p0003	3.576e-08	65.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4PHV3@976|Bacteroidetes,1FK10@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4356583_2	797114.C475_07716	1.545e-09	69.0	COG1520@1|root,arCOG02492@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
YHH1_k127_4363990_0	448385.sce4866	1.398e-127	424.0	COG1215@1|root,COG1215@2|Bacteria,1R6Z6@1224|Proteobacteria,43ARY@68525|delta/epsilon subdivisions,2X661@28221|Deltaproteobacteria,2Z15Y@29|Myxococcales	28221|Deltaproteobacteria	M	Cellulose synthase	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glyco_transf_21
YHH1_k127_4363990_1	269799.Gmet_2032	1.396e-08	65.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42P80@68525|delta/epsilon subdivisions,2WMCB@28221|Deltaproteobacteria,43TGI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
YHH1_k127_4369166_0	745411.B3C1_02980	4.548e-44	169.0	COG0431@1|root,COG0431@2|Bacteria	745411.B3C1_02980|-	S	FMN reductase (NADPH) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4369166_2	398767.Glov_1225	7.159e-14	74.0	2AMWN@1|root,31CTF@2|Bacteria,1NEAZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4369166_1	584708.Apau_1883	2.972e-41	156.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
YHH1_k127_4373900_1	344747.PM8797T_16932	1.962e-11	75.0	COG5653@1|root,COG5653@2|Bacteria,2J2M6@203682|Planctomycetes	203682|Planctomycetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
YHH1_k127_4373900_0	1469607.KK073768_gene3905	1.941e-141	469.0	COG1132@1|root,COG1132@2|Bacteria,1G02Q@1117|Cyanobacteria,1HJ4J@1161|Nostocales	1117|Cyanobacteria	V	ABC transporter, transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
YHH1_k127_4394627_1	926556.Echvi_2128	3.588e-67	235.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,47PIS@768503|Cytophagia	976|Bacteroidetes	M	Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YHH1_k127_4394627_0	243231.GSU2317	1.054e-94	319.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,43S4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
YHH1_k127_441436_1	351607.Acel_1701	5.613e-12	78.0	COG3934@1|root,COG4733@1|root,COG3934@2|Bacteria,COG4733@2|Bacteria,2I2VQ@201174|Actinobacteria	201174|Actinobacteria	G	Cellulose binding domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CBM_3,Glyco_hydro_9,fn3
YHH1_k127_441436_2	471854.Dfer_1553	9.24e-05	48.0	COG4912@1|root,COG4912@2|Bacteria,4NKAY@976|Bacteroidetes,47SNY@768503|Cytophagia	976|Bacteroidetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YHH1_k127_441436_0	1117958.PE143B_0110185	4.805e-16	82.0	COG1396@1|root,COG1396@2|Bacteria,1NN5X@1224|Proteobacteria,1SIT1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
YHH1_k127_4426144_3	946077.W5A_06481	7.608e-24	112.0	2EB0V@1|root,3351R@2|Bacteria,4NX8W@976|Bacteroidetes,1I8U8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4426144_1	1408473.JHXO01000009_gene3259	7.446e-73	256.0	COG0500@1|root,COG0500@2|Bacteria,4NN3A@976|Bacteroidetes,2FSD6@200643|Bacteroidia	976|Bacteroidetes	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4426144_2	1173024.KI912148_gene3735	4.953e-47	172.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	ychN	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
YHH1_k127_4426144_0	1121285.AUFK01000009_gene1275	3.809e-92	310.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1I09P@117743|Flavobacteriia,3ZNVQ@59732|Chryseobacterium	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
YHH1_k127_4431654_1	1121087.AUCK01000006_gene684	3.905e-23	106.0	COG1670@1|root,COG1670@2|Bacteria,1V4F3@1239|Firmicutes,4IPVZ@91061|Bacilli,1ZRDW@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YHH1_k127_4431654_0	517418.Ctha_2308	1.873e-57	208.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1FFK3@1090|Chlorobi	1090|Chlorobi	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
YHH1_k127_4432848_0	340177.Cag_1504	1.894e-103	376.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1FEF0@1090|Chlorobi	1090|Chlorobi	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
YHH1_k127_4432848_3	1267535.KB906767_gene1958	2.694e-39	170.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480,ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
YHH1_k127_4432848_2	1121104.AQXH01000001_gene1675	2.735e-48	181.0	COG2197@1|root,COG2197@2|Bacteria,4NN0B@976|Bacteroidetes	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_4432848_1	1499967.BAYZ01000062_gene6031	6.738e-71	250.0	28K2M@1|root,2Z9RY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH1_k127_4439024_2	240292.Ava_5034	1.928e-41	160.0	COG3224@1|root,COG3224@2|Bacteria,1G3P9@1117|Cyanobacteria,1HP56@1161|Nostocales	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
YHH1_k127_4439024_0	469383.Cwoe_2049	8.372e-67	256.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4CQZX@84995|Rubrobacteria	201174|Actinobacteria	S	Peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
YHH1_k127_4439024_3	385682.AFSL01000088_gene888	1.456e-10	75.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,2FQ8Y@200643|Bacteroidia,3XJQ2@558415|Marinilabiliaceae	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH1_k127_4439024_1	700598.Niako_0136	8.637e-67	243.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1IQPG@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2373 Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
YHH1_k127_4443981_0	2754.EH55_09940	3.019e-77	262.0	COG0740@1|root,COG0740@2|Bacteria,3T9R6@508458|Synergistetes	508458|Synergistetes	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YHH1_k127_4443981_1	714943.Mucpa_0218	3.611e-71	252.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
YHH1_k127_446647_0	755732.Fluta_2092	1.253e-80	297.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
YHH1_k127_4477141_1	762968.HMPREF9441_02852	1.218e-101	337.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,2FNSY@200643|Bacteroidia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YHH1_k127_4477141_0	945713.IALB_2058	3.155e-151	484.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YHH1_k127_4477141_2	945713.IALB_1253	9.019e-29	117.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH1_k127_4508297_0	945713.IALB_0497	1.826e-187	605.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YHH1_k127_4508297_4	945713.IALB_0497	1.566e-31	126.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YHH1_k127_4508297_5	945713.IALB_0498	2.025e-26	118.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
YHH1_k127_4508297_3	945713.IALB_0499	1.329e-42	164.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
YHH1_k127_4508297_1	338963.Pcar_1253	5.136e-97	331.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria,43SEC@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
YHH1_k127_4508297_2	402777.KB235904_gene3184	3.359e-80	274.0	COG4221@1|root,COG4221@2|Bacteria,1G182@1117|Cyanobacteria,1H965@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
YHH1_k127_4515662_1	1519464.HY22_11260	3.76e-164	526.0	COG1219@1|root,COG1219@2|Bacteria,1FD63@1090|Chlorobi	1090|Chlorobi	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
YHH1_k127_4515662_2	56780.SYN_00178	1.016e-126	422.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Q0K@68525|delta/epsilon subdivisions,2WJUW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	dedA	-	3.6.4.13	ko:K03732,ko:K05592	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
YHH1_k127_4515662_3	1229172.JQFA01000004_gene732	5.747e-42	166.0	COG1091@1|root,COG1091@2|Bacteria,1G3IE@1117|Cyanobacteria,1H8GQ@1150|Oscillatoriales	1117|Cyanobacteria	M	dTDP-4-dehydrorhamnose reductase	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
YHH1_k127_4515662_0	945713.IALB_0352	3.905e-279	868.0	COG0556@1|root,COG0556@2|Bacteria	2|Bacteria	L	nucleotide-excision repair	uvrB	GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702,ko:K08999	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH1_k127_4530092_1	927658.AJUM01000034_gene567	0.0002336	46.0	29X8I@1|root,30IXV@2|Bacteria,4P0MB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4530092_0	1341155.FSS13T_21560	1.197e-70	254.0	COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH1_k127_4533921_0	153721.MYP_3548	2.164e-42	168.0	COG3858@1|root,COG3858@2|Bacteria,4NJZ6@976|Bacteroidetes,47QYP@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Glyco_hydro_18,Laminin_G_3
YHH1_k127_4537514_0	945713.IALB_0843	4.988e-32	140.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
YHH1_k127_4537683_2	926562.Oweho_1009	9.028e-31	134.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1HZYF@117743|Flavobacteriia,2PAX0@246874|Cryomorphaceae	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
YHH1_k127_4537683_1	456442.Mboo_1006	2.337e-35	148.0	COG3503@1|root,arCOG04370@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
YHH1_k127_4537683_0	517418.Ctha_2023	3.208e-178	578.0	COG0367@1|root,COG0367@2|Bacteria,1FDEI@1090|Chlorobi	1090|Chlorobi	F	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
YHH1_k127_4537683_3	269799.Gmet_1068	2.21e-12	81.0	COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,42SBY@68525|delta/epsilon subdivisions,2WPSK@28221|Deltaproteobacteria,43V9B@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4547224_4	357808.RoseRS_3676	9.336e-18	88.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi,375IZ@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
YHH1_k127_4547224_1	945713.IALB_2123	1.255e-74	254.0	COG0377@1|root,COG0377@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YHH1_k127_4547224_0	1191523.MROS_0175	1.287e-215	685.0	COG1022@1|root,COG1022@2|Bacteria	2|Bacteria	I	Amp-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
YHH1_k127_4547224_3	251229.Chro_3808	1.474e-27	125.0	2CCSR@1|root,32RWC@2|Bacteria,1GEQ5@1117|Cyanobacteria,3VKJG@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YHH1_k127_4547224_2	936572.HMPREF1148_1160	5.626e-57	202.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4H2G4@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YHH1_k127_4557614_0	771875.Ferpe_0663	2.682e-101	339.0	COG1052@1|root,COG1052@2|Bacteria,2GC25@200918|Thermotogae	200918|Thermotogae	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH1_k127_4557614_1	1449050.JNLE01000003_gene2834	4.272e-57	203.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,36F17@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
YHH1_k127_4581065_0	504472.Slin_1189	9.177e-63	227.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,47MU2@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH1_k127_4581065_1	1094466.KQS_08940	4.856e-12	80.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,1I0G4@117743|Flavobacteriia,2NT7Y@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,He_PIG,fn3
YHH1_k127_4586683_0	1121405.dsmv_3003	1.457e-321	997.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
YHH1_k127_4607717_2	998088.B565_3144	0.000276	54.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1Y42S@135624|Aeromonadales	1236|Gammaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,UvrD-helicase,UvrD_C
YHH1_k127_4607717_0	886379.AEWI01000018_gene1318	1.751e-08	68.0	COG0514@1|root,COG0514@2|Bacteria,4NIG1@976|Bacteroidetes,2FPYY@200643|Bacteroidia	976|Bacteroidetes	L	helicase superfamily c-terminal domain	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
YHH1_k127_4607717_1	1057002.KB905370_gene5650	9.421e-07	61.0	COG1196@1|root,COG1196@2|Bacteria,1MVEP@1224|Proteobacteria,2TR50@28211|Alphaproteobacteria,4B7WK@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	Apolipoprotein A1/A4/E domain	-	-	-	-	-	-	-	-	-	-	-	-	Apolipoprotein
YHH1_k127_4610485_2	1408473.JHXO01000012_gene275	3.892e-55	196.0	COG1162@1|root,COG1162@2|Bacteria,4NE24@976|Bacteroidetes,2FM8Z@200643|Bacteroidia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
YHH1_k127_4610485_0	1123057.P872_13660	3.862e-147	474.0	COG3177@1|root,COG3177@2|Bacteria,4NF0H@976|Bacteroidetes,47JUU@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
YHH1_k127_4610485_4	760192.Halhy_4085	3.579e-22	96.0	COG0488@1|root,COG0488@2|Bacteria,4NF6E@976|Bacteroidetes,1INT2@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH1_k127_4610485_1	945713.IALB_2176	4.842e-84	284.0	COG0854@1|root,COG0854@2|Bacteria	2|Bacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
YHH1_k127_4610485_3	309807.SRU_0943	1.094e-30	123.0	COG1266@1|root,COG1266@2|Bacteria,4PEJM@976|Bacteroidetes,1FJ86@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4613134_0	243231.GSU0451	7.668e-78	266.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,43SE9@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_4613134_1	330214.NIDE0304	9.631e-56	208.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,3J11K@40117|Nitrospirae	40117|Nitrospirae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YHH1_k127_4613134_2	1121104.AQXH01000001_gene1024	8.315e-21	98.0	2BWJ4@1|root,2ZMM0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4621389_0	279714.FuraDRAFT_0828	2.354e-64	227.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2VJWJ@28216|Betaproteobacteria,2KTWA@206351|Neisseriales	206351|Neisseriales	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
YHH1_k127_4621389_1	756272.Plabr_1526	2.41e-51	197.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,2IYFX@203682|Planctomycetes	203682|Planctomycetes	KTU	Flp pilus assembly protein, ATPase CpaE	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,Response_reg
YHH1_k127_4621389_2	1121434.AULY01000009_gene2038	6.374e-50	189.0	COG4961@1|root,COG4961@2|Bacteria,1NIG7@1224|Proteobacteria,42X7K@68525|delta/epsilon subdivisions,2WSKV@28221|Deltaproteobacteria,2M9N1@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
YHH1_k127_4621389_4	1395571.TMS3_0117395	0.000946	44.0	COG4961@1|root,COG4961@2|Bacteria,1R58C@1224|Proteobacteria,1S1A4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
YHH1_k127_4621389_3	883.DvMF_2741	8.215e-20	92.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,42PA6@68525|delta/epsilon subdivisions,2WIIY@28221|Deltaproteobacteria,2M858@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
YHH1_k127_4622597_0	945713.IALB_1250	1.201e-163	523.0	COG1690@1|root,COG1690@2|Bacteria	2|Bacteria	S	RNA ligase activity	rtcB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
YHH1_k127_4740519_1	575540.Isop_0240	4.183e-12	77.0	COG2304@1|root,COG2304@2|Bacteria,2IY1T@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA,VWA_3
YHH1_k127_4740519_2	1089550.ATTH01000001_gene1531	8.083e-09	66.0	COG2911@1|root,COG3210@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,4NTNN@976|Bacteroidetes	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
YHH1_k127_4740519_3	203275.BFO_2676	8.499e-07	57.0	2FJRB@1|root,34BE7@2|Bacteria,4P5QR@976|Bacteroidetes,2FYTE@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4740519_0	1121930.AQXG01000016_gene1824	4.319e-107	358.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1IPB4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	yheS_3	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH1_k127_4743678_2	1408437.JNJN01000024_gene232	3.505e-36	139.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,25V4E@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
YHH1_k127_4743678_1	1034769.KB910518_gene277	1.941e-79	276.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_4743678_0	1191523.MROS_1713	3.349e-136	453.0	COG0497@1|root,COG0497@2|Bacteria	2|Bacteria	L	DNA recombination	recN	-	-	ko:K03631,ko:K07459,ko:K20345	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000,ko03400	3.A.1.112,8.A.1	-	-	SMC_N,YkyA
YHH1_k127_4748139_0	1158318.ATXC01000001_gene910	1.319e-46	172.0	COG0698@1|root,COG0698@2|Bacteria,2G43P@200783|Aquificae	200783|Aquificae	G	ribose 5-phosphate isomerase B	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
YHH1_k127_4748139_1	1191523.MROS_0049	2.149e-40	168.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_0049|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4748139_2	518766.Rmar_1686	8.369e-08	57.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1FJ5N@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4750412_2	1121104.AQXH01000002_gene506	1.891e-16	91.0	COG0737@1|root,COG3391@1|root,COG0737@2|Bacteria,COG3391@2|Bacteria,4NUYI@976|Bacteroidetes	976|Bacteroidetes	F	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4750412_1	926569.ANT_21400	3.149e-26	112.0	COG4737@1|root,COG4737@2|Bacteria	2|Bacteria	G	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
YHH1_k127_4750412_0	379066.GAU_3713	1.296e-26	113.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	Fer4,HTH_3,HTH_31
YHH1_k127_4750412_3	506534.Rhein_2591	1.412e-13	79.0	2EBEE@1|root,335F1@2|Bacteria,1NCUB@1224|Proteobacteria,1SDGB@1236|Gammaproteobacteria,1X1NG@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4751146_0	498761.HM1_2016	3.981e-114	379.0	COG4268@1|root,COG4268@2|Bacteria,1VPTS@1239|Firmicutes,256ZX@186801|Clostridia	186801|Clostridia	V	McrBC 5-methylcytosine restriction system component	-	-	-	-	-	-	-	-	-	-	-	-	McrBC
YHH1_k127_4769245_3	309807.SRU_2105	5.072e-14	72.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1FIWX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
YHH1_k127_4769245_2	880073.Calab_0309	8.158e-45	170.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YHH1_k127_4769245_1	880073.Calab_0308	1.003e-53	198.0	COG2010@1|root,COG2010@2|Bacteria,2NPQJ@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YHH1_k127_4769245_0	880073.Calab_0307	5.019e-65	235.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4779730_2	331678.Cphamn1_2264	4.307e-30	124.0	COG0215@1|root,COG0215@2|Bacteria,1FDEC@1090|Chlorobi	1090|Chlorobi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
YHH1_k127_4779730_1	880073.Calab_0980	4.182e-42	160.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YHH1_k127_4779730_0	880073.Calab_0981	3.752e-43	169.0	COG0628@1|root,COG0628@2|Bacteria,2NPYJ@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YHH1_k127_4793891_1	504472.Slin_1224	5.674e-55	215.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,47M3M@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
YHH1_k127_4793891_0	690850.Desaf_1652	6.665e-166	541.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2WJY9@28221|Deltaproteobacteria,2M8FD@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	SMART Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
YHH1_k127_4796288_1	1120999.JONM01000009_gene349	1.856e-46	177.0	2EB3X@1|root,3354K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4796288_0	56110.Oscil6304_0542	3.225e-107	370.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
YHH1_k127_4798299_1	880073.Calab_1823	3.757e-64	244.0	COG0860@1|root,COG4412@1|root,COG0860@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	bpr	GO:0005575,GO:0005576	3.4.17.14,3.5.1.28	ko:K01448,ko:K07260,ko:K09955,ko:K13276	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036,ko03110	-	-	-	CHAP,CarbopepD_reg_2,CarboxypepD_reg,GBS_Bsp-like,Glyco_hydro_25,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8,SH3_5,VanY,YSIRK_signal
YHH1_k127_4798299_2	1434325.AZQN01000006_gene3399	5.711e-56	206.0	COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes,47PD6@768503|Cytophagia	976|Bacteroidetes	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
YHH1_k127_4798299_0	1125863.JAFN01000001_gene724	1.785e-64	227.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_4800407_1	1227453.C444_13327	1.376e-06	57.0	COG4948@1|root,arCOG01168@2157|Archaea,2XUAK@28890|Euryarchaeota,23UEE@183963|Halobacteria	183963|Halobacteria	M	COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	ykfB2	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YHH1_k127_4800407_0	880072.Desac_0427	8.069e-56	208.0	COG0784@1|root,COG1719@1|root,COG4191@1|root,COG0784@2|Bacteria,COG1719@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MRI2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,dCache_1
YHH1_k127_4802796_2	929556.Solca_1164	1.964e-29	122.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1IP3C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YHH1_k127_4802796_1	1191523.MROS_2549	1.63e-200	637.0	COG1190@1|root,COG1190@2|Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
YHH1_k127_4802796_0	1191523.MROS_1633	6.609e-251	791.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	ACPS,CBM9_1
YHH1_k127_4805467_1	243275.TDE_2210	7.6e-92	319.0	2EYV8@1|root,33S2C@2|Bacteria,2J65B@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1565
YHH1_k127_4805467_2	1379698.RBG1_1C00001G0272	8.6e-33	135.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,DUF2505
YHH1_k127_4805467_0	1499967.BAYZ01000057_gene4710	1.817e-111	366.0	COG0501@1|root,COG0501@2|Bacteria,2NS4G@2323|unclassified Bacteria	2|Bacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH1_k127_4812006_1	1121373.KB903624_gene2496	8.569e-08	64.0	2C5KB@1|root,2ZCDW@2|Bacteria,4NMNY@976|Bacteroidetes,47PDN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4812006_0	945713.IALB_3203	5.613e-72	261.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	plpD	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
YHH1_k127_4824249_1	472759.Nhal_3325	8.989e-45	171.0	COG2244@1|root,COG2244@2|Bacteria,1MWKV@1224|Proteobacteria,1S4AZ@1236|Gammaproteobacteria,1X1CX@135613|Chromatiales	135613|Chromatiales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
YHH1_k127_4824249_0	472759.Nhal_3326	2.075e-102	341.0	COG4424@1|root,COG4424@2|Bacteria,1N77D@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
YHH1_k127_4831988_0	945713.IALB_2086	2.517e-99	345.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YHH1_k127_4831988_2	945713.IALB_2085	4.058e-44	178.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	3.1.21.3	ko:K01153,ko:K05789,ko:K07011,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01005,ko02000,ko02048	8.A.3.1	-	-	GNVR,Wzz
YHH1_k127_4831988_3	1220534.B655_0879	6.331e-23	113.0	COG2244@1|root,arCOG02209@2157|Archaea,2XSUR@28890|Euryarchaeota,23PBE@183925|Methanobacteria	183925|Methanobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
YHH1_k127_4831988_1	926550.CLDAP_16140	2.833e-46	176.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
YHH1_k127_4840140_2	643867.Ftrac_3380	1.958e-12	69.0	COG0664@1|root,COG0664@2|Bacteria,4NKW5@976|Bacteroidetes,47N83@768503|Cytophagia	976|Bacteroidetes	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YHH1_k127_4840140_0	1121007.AUML01000062_gene614	4.422e-37	143.0	COG4096@1|root,COG4096@2|Bacteria,4NH89@976|Bacteroidetes,1HYP2@117743|Flavobacteriia,2YKZE@290174|Aquimarina	976|Bacteroidetes	L	EcoEI R protein C-terminal	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,Helicase_C,ResIII
YHH1_k127_4840140_1	1313421.JHBV01000039_gene2796	1.732e-21	97.0	2DNQV@1|root,32YMJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
YHH1_k127_4850767_1	1517682.HW49_04530	0.0008576	48.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia,22X5K@171551|Porphyromonadaceae	976|Bacteroidetes	G	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
YHH1_k127_4850767_0	1191523.MROS_1500	3.27e-115	383.0	COG3174@1|root,COG3174@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
YHH1_k127_4863183_0	1047013.AQSP01000115_gene361	3.867e-52	192.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_4863183_1	1123518.ARWI01000001_gene1170	1.716e-36	154.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,4604X@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
YHH1_k127_4886642_0	945713.IALB_2197	8.292e-86	297.0	COG0587@1|root,COG0587@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	dnaE-2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YHH1_k127_4886642_1	443143.GM18_0341	8.708e-72	258.0	COG2133@1|root,COG2133@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4894091_1	517418.Ctha_0964	1.688e-90	304.0	COG0767@1|root,COG0767@2|Bacteria,1FEE8@1090|Chlorobi	1090|Chlorobi	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YHH1_k127_4894091_0	1122176.KB903556_gene4071	2.667e-92	316.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1IWI9@117747|Sphingobacteriia	976|Bacteroidetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
YHH1_k127_4894091_2	945713.IALB_0840	4.235e-47	179.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
YHH1_k127_4894091_3	1237149.C900_03673	5.34e-35	149.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,47JZE@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
YHH1_k127_4894091_4	765911.Thivi_3434	1.481e-09	62.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YHH1_k127_4899940_0	945713.IALB_1578	2.802e-47	188.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	bprV	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PPC,Peptidase_S8
YHH1_k127_4899940_1	1237500.ANBA01000009_gene858	3.272e-19	91.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4EJ3X@85012|Streptosporangiales	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YHH1_k127_4912562_2	309807.SRU_2098	4.183e-12	69.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1FJ6D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Cytochrome c oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
YHH1_k127_4912562_0	1089550.ATTH01000001_gene1599	1.938e-64	234.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,1FIYT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
YHH1_k127_4912562_1	478741.JAFS01000001_gene1116	2.505e-44	174.0	COG1612@1|root,COG1612@2|Bacteria,46T3F@74201|Verrucomicrobia,37G83@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
YHH1_k127_4919550_0	1265845.PWEIH_06816	5.164e-38	156.0	COG4641@1|root,COG4641@2|Bacteria,1TR7G@1239|Firmicutes,4HFIT@91061|Bacilli,26MF4@186820|Listeriaceae	91061|Bacilli	S	DUF based on E. rectale Gene description (DUF3880)	cgeB1	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
YHH1_k127_4919550_1	373903.Hore_22830	6.122e-21	100.0	COG0438@1|root,COG0438@2|Bacteria,1V2NV@1239|Firmicutes,25ERN@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.348	ko:K06338,ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_4958157_2	1288494.EBAPG3_8090	3.801e-26	111.0	COG4122@1|root,COG4122@2|Bacteria,1R4VI@1224|Proteobacteria,2VY9I@28216|Betaproteobacteria,374Q8@32003|Nitrosomonadales	28216|Betaproteobacteria	H	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
YHH1_k127_4958157_1	1031288.AXAA01000033_gene1347	9.234e-34	140.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,36GX1@31979|Clostridiaceae	186801|Clostridia	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
YHH1_k127_4958157_0	1191523.MROS_0741	5.803e-61	216.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_4958157_3	243231.GSU2146	7.556e-22	101.0	COG3439@1|root,COG3439@2|Bacteria,1RHJQ@1224|Proteobacteria,42X8S@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
YHH1_k127_4978857_0	755732.Fluta_2945	5.874e-65	253.0	COG2931@1|root,COG3291@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
YHH1_k127_4993192_2	383372.Rcas_1251	1.632e-42	158.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,376DV@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH1_k127_4993192_1	945713.IALB_1503	1.177e-65	238.0	COG0618@1|root,COG0618@2|Bacteria	2|Bacteria	S	phosphoesterase RecJ domain protein	nrnA	GO:0008150,GO:0040007	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH1_k127_4993192_0	1191523.MROS_1034	5.831e-98	332.0	COG0252@1|root,COG0252@2|Bacteria	2|Bacteria	EJ	asparaginase activity	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
YHH1_k127_4993192_3	945713.IALB_1693	4.178e-24	109.0	28HA8@1|root,2Z7MQ@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
YHH1_k127_4993200_0	269797.Mbar_A3736	7.151e-12	79.0	COG1520@1|root,COG3291@1|root,arCOG02482@2157|Archaea,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
YHH1_k127_5008337_2	945713.IALB_2177	1.225e-19	94.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YHH1_k127_5008337_0	945713.IALB_2606	4.782e-74	260.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
YHH1_k127_5008337_1	1408433.JHXV01000029_gene3119	6.836e-20	92.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1HYHD@117743|Flavobacteriia,2PABG@246874|Cryomorphaceae	976|Bacteroidetes	S	FMN-dependent dehydrogenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
YHH1_k127_5014028_0	1313421.JHBV01000028_gene1857	1.314e-72	269.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
YHH1_k127_5026207_3	926550.CLDAP_07380	1.253e-16	81.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YHH1_k127_5026207_2	1191523.MROS_2417	2.111e-24	108.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YHH1_k127_5026207_0	945713.IALB_1702	1.345e-159	516.0	COG0617@1|root,COG0617@2|Bacteria	2|Bacteria	J	CTP:tRNA cytidylyltransferase activity	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
YHH1_k127_5026207_1	1191523.MROS_2280	1.243e-52	202.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
YHH1_k127_5044333_0	153721.MYP_2602	4.159e-67	248.0	COG1572@1|root,COG2931@1|root,COG3227@1|root,COG3266@1|root,COG3291@1|root,COG4447@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
YHH1_k127_5064088_2	84531.JMTZ01000047_gene1070	4.342e-07	58.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,1RR5T@1236|Gammaproteobacteria,1XA3C@135614|Xanthomonadales	135614|Xanthomonadales	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
YHH1_k127_5064088_1	44251.PDUR_21475	7.577e-18	97.0	28NCT@1|root,2ZBFR@2|Bacteria,1UKIC@1239|Firmicutes,4HF21@91061|Bacilli,26R8W@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5064088_0	215803.DB30_7633	8.322e-44	171.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2YUPX@29|Myxococcales	28221|Deltaproteobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
YHH1_k127_5064309_3	945713.IALB_1376	1.515e-25	109.0	COG0035@1|root,COG0035@2|Bacteria	2|Bacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004845,GO:0004849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016763,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iAF1260.b2498,iAPECO1_1312.APECO1_4071,iB21_1397.B21_02352,iBWG_1329.BWG_2262,iE2348C_1286.E2348C_2723,iEC042_1314.EC042_2699,iEC55989_1330.EC55989_2783,iECABU_c1320.ECABU_c27980,iECBD_1354.ECBD_1190,iECB_1328.ECB_02390,iECDH10B_1368.ECDH10B_2664,iECDH1ME8569_1439.ECDH1ME8569_2424,iECD_1391.ECD_02390,iECED1_1282.ECED1_2921,iECH74115_1262.ECH74115_3720,iECIAI1_1343.ECIAI1_2550,iECIAI39_1322.ECIAI39_2639,iECNA114_1301.ECNA114_2571,iECO103_1326.ECO103_3015,iECO111_1330.ECO111_3222,iECO26_1355.ECO26_3545,iECOK1_1307.ECOK1_2794,iECP_1309.ECP_2500,iECS88_1305.ECS88_2669,iECSE_1348.ECSE_2784,iECSF_1327.ECSF_2339,iECSP_1301.ECSP_3437,iECUMN_1333.ECUMN_2811,iECW_1372.ECW_m2721,iEKO11_1354.EKO11_1236,iETEC_1333.ETEC_2603,iEcDH1_1363.EcDH1_1171,iEcE24377_1341.EcE24377A_2781,iEcHS_1320.EcHS_A2633,iEcSMS35_1347.EcSMS35_2645,iEcolC_1368.EcolC_1178,iG2583_1286.G2583_3021,iJN746.PP_0746,iJO1366.b2498,iJR904.b2498,iLF82_1304.LF82_2383,iNRG857_1313.NRG857_12410,iSFV_1184.SFV_2543,iSF_1195.SF2542,iS_1188.S2691,iSbBS512_1146.SbBS512_E2872,iUMN146_1321.UM146_04235,iUMNK88_1353.UMNK88_3094,iWFL_1372.ECW_m2721,iY75_1357.Y75_RS13040,ic_1306.c3015	UPRTase
YHH1_k127_5064309_1	204669.Acid345_2245	1.87e-91	321.0	COG0053@1|root,COG0053@2|Bacteria,3Y43E@57723|Acidobacteria,2JIIM@204432|Acidobacteriia	204432|Acidobacteriia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
YHH1_k127_5064309_2	985053.VMUT_0453	7.327e-38	149.0	COG1853@1|root,arCOG02017@2157|Archaea,2XRAH@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
YHH1_k127_5064309_0	945713.IALB_1478	7.179e-270	836.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	pcd	GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH1_k127_5064309_4	177437.HRM2_38590	4.237e-11	65.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
YHH1_k127_507886_1	1519464.HY22_02470	3.367e-60	216.0	COG1619@1|root,COG1619@2|Bacteria,1FDWQ@1090|Chlorobi	1090|Chlorobi	V	PFAM peptidase U61, LD-carboxypeptidase A	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
YHH1_k127_507886_0	944480.ATUV01000001_gene954	1.422e-92	315.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2M6YN@213113|Desulfurellales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YHH1_k127_507886_2	1356852.N008_13715	6.81e-46	172.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,47KG4@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
YHH1_k127_5085879_2	518766.Rmar_1315	9.113e-111	372.0	COG0612@1|root,COG0612@2|Bacteria,4NEE4@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_5085879_0	1379698.RBG1_1C00001G1045	2.155e-149	485.0	COG0436@1|root,COG0436@2|Bacteria,2NP0E@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS10450	Aminotran_1_2
YHH1_k127_5085879_1	945713.IALB_0893	5.552e-132	424.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
YHH1_k127_5086384_1	391612.CY0110_28974	7.26e-08	64.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	ko:K06915,ko:K19172	-	-	-	-	ko00000,ko02048	-	-	-	DUF853,DUF87,PLDc_2
YHH1_k127_5086384_0	880073.Calab_0453	1.783e-126	421.0	COG2812@1|root,COG2812@2|Bacteria,2NNK7@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
YHH1_k127_5090008_4	1121930.AQXG01000004_gene2867	2.377e-20	100.0	COG1404@1|root,COG4254@1|root,COG1404@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FecR
YHH1_k127_5090008_0	1313421.JHBV01000028_gene1857	1.026e-102	377.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
YHH1_k127_5090008_6	1453498.LG45_04870	5.224e-12	81.0	COG1345@1|root,COG2356@1|root,COG3420@1|root,COG1345@2|Bacteria,COG2356@2|Bacteria,COG3420@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia,2P0S4@237|Flavobacterium	976|Bacteroidetes	N	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	ASH,He_PIG,PA14,TIG
YHH1_k127_5090008_2	1237149.C900_03132	1.708e-48	201.0	COG2353@1|root,COG2353@2|Bacteria,4NUV8@976|Bacteroidetes,47UW8@768503|Cytophagia	1237149.C900_03132|-	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5090008_5	203119.Cthe_0817	9.461e-20	106.0	COG2199@1|root,COG3899@1|root,COG3706@2|Bacteria,COG3899@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,Pkinase,TPR_12,TPR_8
YHH1_k127_5090008_3	1267535.KB906767_gene1958	2.104e-39	171.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480,ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
YHH1_k127_5090008_1	1267535.KB906767_gene1959	1.096e-49	184.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_5095245_1	1347393.HG726021_gene311	3.616e-39	161.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,4AKSZ@815|Bacteroidaceae	976|Bacteroidetes	T	COG NOG22299 non supervised orthologous group	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
YHH1_k127_5095245_0	1191523.MROS_0394	1.171e-107	372.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_0394|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5099047_1	1150600.ADIARSV_2724	1.541e-48	177.0	COG3696@1|root,COG3696@2|Bacteria,4NFD2@976|Bacteroidetes,1IPX9@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH1_k127_5099047_2	1356852.N008_20300	4.587e-22	111.0	COG4633@1|root,COG4633@2|Bacteria,4P6N2@976|Bacteroidetes	976|Bacteroidetes	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
YHH1_k127_5099047_0	443143.GM18_2075	2.003e-92	323.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
YHH1_k127_5099047_3	1123519.PSJM300_10645	4.199e-06	50.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,1RRRP@1236|Gammaproteobacteria,1Z0GS@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	MU	COG1538 Outer membrane protein	cebC	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH1_k127_5101458_0	331678.Cphamn1_2523	8.491e-87	301.0	COG0772@1|root,COG0772@2|Bacteria,1FDI2@1090|Chlorobi	1090|Chlorobi	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
YHH1_k127_5101458_1	518766.Rmar_2703	1.446e-86	298.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1FITH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH1_k127_5121028_0	649349.Lbys_2991	1.564e-73	282.0	COG3179@1|root,COG3179@2|Bacteria,4NF8K@976|Bacteroidetes,47QM0@768503|Cytophagia	976|Bacteroidetes	S	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
YHH1_k127_5129957_1	153721.MYP_1672	1.408e-49	181.0	COG4912@1|root,COG4912@2|Bacteria,4NNBG@976|Bacteroidetes,47SXA@768503|Cytophagia	976|Bacteroidetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YHH1_k127_5129957_0	945713.IALB_0222	2.203e-83	297.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	yjcH	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
YHH1_k127_5149869_1	10228.TriadP18858	2.796e-09	64.0	COG0277@1|root,KOG4730@2759|Eukaryota,38E7K@33154|Opisthokonta,3BJIG@33208|Metazoa	33208|Metazoa	V	L-gulonolactone oxidase-like	Gulo	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0012505,GO:0016020,GO:0016051,GO:0016053,GO:0016491,GO:0016614,GO:0016899,GO:0019752,GO:0019852,GO:0019853,GO:0031090,GO:0031984,GO:0036094,GO:0042175,GO:0042364,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046364,GO:0046394,GO:0048037,GO:0050105,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:0098827,GO:1901265,GO:1901363,GO:1901576	1.1.3.8	ko:K00103	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
YHH1_k127_5149869_0	1047013.AQSP01000114_gene701	4.63e-58	207.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
YHH1_k127_5164837_5	111780.Sta7437_1577	4.235e-05	54.0	COG1943@1|root,COG1943@2|Bacteria,1G79U@1117|Cyanobacteria,3VK18@52604|Pleurocapsales	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_5164837_3	1121935.AQXX01000117_gene5104	2.645e-61	216.0	arCOG05193@1|root,2ZZSG@2|Bacteria,1REJB@1224|Proteobacteria,1SQYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5164837_2	945713.IALB_1173	4.629e-67	239.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	ydiY	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF3078,DUF481
YHH1_k127_5164837_4	1166018.FAES_0541	1.429e-22	114.0	28HMX@1|root,2Z7WB@2|Bacteria,4NFY2@976|Bacteroidetes,47MX8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5164837_1	742817.HMPREF9449_01085	1.886e-69	245.0	COG1131@1|root,COG1131@2|Bacteria,4NJ0D@976|Bacteroidetes,2FQ27@200643|Bacteroidia,22Y6G@171551|Porphyromonadaceae	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_5164837_0	700598.Niako_5053	2.033e-75	276.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_5166469_1	941449.dsx2_2855	2.574e-10	64.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2WSJG@28221|Deltaproteobacteria,2M9UP@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_5166469_0	1183438.GKIL_0303	9.793e-19	89.0	COG0494@1|root,COG0494@2|Bacteria,1GFG0@1117|Cyanobacteria	1117|Cyanobacteria	L	COG494 NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair General function prediction only	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
YHH1_k127_5169687_2	1173024.KI912152_gene799	4.239e-07	52.0	COG1487@1|root,COG1487@2|Bacteria,1G6RD@1117|Cyanobacteria,1JM92@1189|Stigonemataceae	1117|Cyanobacteria	S	PIN domain	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH1_k127_5169687_0	1121930.AQXG01000002_gene2048	2.264e-42	159.0	2B1QU@1|root,31U6H@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
YHH1_k127_5169687_1	1123234.AUKI01000017_gene2480	8.086e-36	146.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH1_k127_5178112_5	945713.IALB_1329	1.858e-68	241.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria	2|Bacteria	S	nicotinamide-nucleotide amidase activity	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
YHH1_k127_5178112_4	945713.IALB_2193	3.33e-70	241.0	COG2065@1|root,COG2065@2|Bacteria	2|Bacteria	F	uracil phosphoribosyltransferase activity	pyrR	GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
YHH1_k127_5178112_1	1191523.MROS_0336	7.512e-139	449.0	COG0540@1|root,COG0540@2|Bacteria	2|Bacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15490	OTCace,OTCace_N
YHH1_k127_5178112_2	518766.Rmar_0997	1.452e-131	432.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1FJ22@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
YHH1_k127_5178112_6	111780.Sta7437_1577	7.999e-06	57.0	COG1943@1|root,COG1943@2|Bacteria,1G79U@1117|Cyanobacteria,3VK18@52604|Pleurocapsales	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_5178112_0	945713.IALB_0746	6.839e-152	504.0	COG1086@1|root,COG1216@1|root,COG2148@1|root,COG1086@2|Bacteria,COG1216@2|Bacteria,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	wbbL	-	-	ko:K03606,ko:K07011	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
YHH1_k127_5178112_3	1191523.MROS_0294	5.115e-84	281.0	COG0825@1|root,COG0825@2|Bacteria	2|Bacteria	I	malonyl-CoA biosynthetic process	accA	GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN678.accA,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197	ACCA
YHH1_k127_5197456_1	344747.PM8797T_31033	4.954e-29	123.0	2CVD4@1|root,30Q82@2|Bacteria,2J0S1@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5197456_0	583355.Caka_1904	4.026e-66	239.0	COG3380@1|root,COG3380@2|Bacteria	2|Bacteria	S	monoamine oxidase activity	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
YHH1_k127_5199936_0	269798.CHU_2528	3.056e-23	114.0	COG3291@1|root,COG3866@1|root,COG3291@2|Bacteria,COG3866@2|Bacteria,4NDZC@976|Bacteroidetes,47K2W@768503|Cytophagia	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA
YHH1_k127_5207865_2	448385.sce2087	5.812e-50	186.0	2AAD4@1|root,30ZP1@2|Bacteria,1NBWF@1224|Proteobacteria,437DS@68525|delta/epsilon subdivisions,2X2JW@28221|Deltaproteobacteria,2Z150@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5207865_1	1215092.PA6_046_00220	2.27e-109	354.0	2DB76@1|root,2Z7JZ@2|Bacteria,1R41X@1224|Proteobacteria,1S1J8@1236|Gammaproteobacteria,1YIS6@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
YHH1_k127_5207865_0	1123392.AQWL01000008_gene1222	1.517e-201	634.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,2VM4U@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
YHH1_k127_521958_2	1519464.HY22_03685	2.93e-56	205.0	COG0760@1|root,COG0760@2|Bacteria,1FDC8@1090|Chlorobi	1090|Chlorobi	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N,SurA_N_3
YHH1_k127_521958_0	886379.AEWI01000012_gene1067	5.023e-113	378.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,2FWT4@200643|Bacteroidia,3XJC6@558415|Marinilabiliaceae	976|Bacteroidetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_521958_1	517418.Ctha_1581	2.547e-75	271.0	COG0612@1|root,COG0612@2|Bacteria,1FEWA@1090|Chlorobi	1090|Chlorobi	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_5226435_2	1313421.JHBV01000015_gene5729	3.389e-12	79.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Gram_pos_anchor
YHH1_k127_5226435_0	545694.TREPR_0418	1.011e-44	183.0	COG1262@1|root,COG1262@2|Bacteria,2J5Y8@203691|Spirochaetes	203691|Spirochaetes	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Flavodoxin_4
YHH1_k127_5226435_3	945713.IALB_1488	6.509e-08	65.0	COG3291@1|root,COG4409@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4409@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	wcoB	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta_helix,PKD,Reprolysin_4
YHH1_k127_5226435_1	1121456.ATVA01000011_gene1875	1.418e-34	142.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2M8RR@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
YHH1_k127_5226508_1	1215114.BBIU01000005_gene634	2.772e-50	188.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,1SYCI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Guanine deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
YHH1_k127_5226508_0	909663.KI867150_gene2054	3.268e-77	267.0	COG2836@1|root,COG2836@2|Bacteria,1QVGG@1224|Proteobacteria,432GS@68525|delta/epsilon subdivisions,2WXZW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
YHH1_k127_5226508_2	570952.ATVH01000013_gene3098	1.025e-47	174.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2JS8T@204441|Rhodospirillales	204441|Rhodospirillales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
YHH1_k127_5234867_0	880073.Calab_1837	1.543e-14	89.0	COG4677@1|root,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Lipase_GDSL_2,NosD,Pectate_lyase_3
YHH1_k127_5234867_1	1286171.EAL2_c20530	0.0008014	52.0	COG3209@1|root,COG4886@1|root,COG3209@2|Bacteria,COG4886@2|Bacteria,1UYAG@1239|Firmicutes,25BZ5@186801|Clostridia	186801|Clostridia	M	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5244914_0	1166018.FAES_0081	2.366e-05	50.0	COG3204@1|root,COG3204@2|Bacteria,4NNX0@976|Bacteroidetes,47P1B@768503|Cytophagia	976|Bacteroidetes	L	pilus organization	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5259883_1	1123008.KB905697_gene3219	3.893e-60	223.0	COG0845@1|root,COG0845@2|Bacteria,4NGSC@976|Bacteroidetes,2FY71@200643|Bacteroidia	976|Bacteroidetes	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
YHH1_k127_5259883_0	880073.Calab_1579	2.512e-91	320.0	COG0577@1|root,COG0577@2|Bacteria,2NP20@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	macB_1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_5259883_2	880073.Calab_1197	8.998e-50	196.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH1_k127_5259883_3	1121346.KB899818_gene2558	1.82e-12	72.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,26SDE@186822|Paenibacillaceae	91061|Bacilli	S	Helix-turn-helix domain	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
YHH1_k127_5263053_0	1191523.MROS_2798	3.818e-153	492.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
YHH1_k127_5263053_1	1499967.BAYZ01000119_gene3214	5.084e-95	320.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
YHH1_k127_5277183_3	1089550.ATTH01000001_gene1580	1.541e-33	130.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1FJAI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
YHH1_k127_5277183_0	1191523.MROS_1985	1.885e-78	271.0	COG0302@1|root,COG0302@2|Bacteria	2|Bacteria	H	gtp cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
YHH1_k127_5277183_1	1120973.AQXL01000105_gene2562	2.616e-37	149.0	COG4221@1|root,COG4221@2|Bacteria,1V9C1@1239|Firmicutes,4ISDS@91061|Bacilli	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH1_k127_5277183_2	869210.Marky_1948	5.756e-37	158.0	COG4221@1|root,COG4221@2|Bacteria,1WIDQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH1_k127_528333_1	391625.PPSIR1_31468	1.822e-31	131.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria,2YU8N@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_528333_0	880073.Calab_1151	1.305e-244	781.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_5311383_0	1499967.BAYZ01000081_gene1057	4.217e-205	648.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gluD	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
YHH1_k127_5319999_1	1278073.MYSTI_01203	7.945e-96	327.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,42QXC@68525|delta/epsilon subdivisions,2WN3M@28221|Deltaproteobacteria,2Z0A5@29|Myxococcales	28221|Deltaproteobacteria	O	FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
YHH1_k127_5319999_0	251221.35211937	4.402e-168	537.0	COG0520@1|root,COG0520@2|Bacteria,1G15D@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YHH1_k127_5327944_0	234267.Acid_5283	4.287e-104	353.0	COG0436@1|root,COG0436@2|Bacteria,3Y2VQ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH1_k127_5327944_1	653733.Selin_2294	9.588e-66	229.0	COG2193@1|root,COG2193@2|Bacteria	2|Bacteria	P	ferroxidase activity	bfr	GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
YHH1_k127_5337694_0	945713.IALB_0893	1e-139	455.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
YHH1_k127_5337694_1	861299.J421_3288	4.208e-103	345.0	COG1005@1|root,COG1005@2|Bacteria,1ZTDY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH1_k127_5337694_2	945713.IALB_0895	2.356e-44	163.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00338,ko:K02573	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
YHH1_k127_5339066_0	941449.dsx2_0720	7.271e-175	555.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2M885@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
YHH1_k127_5339066_2	765912.Thimo_1923	1.442e-27	114.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,1WYKM@135613|Chromatiales	135613|Chromatiales	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_5339066_1	671143.DAMO_2205	1.453e-139	455.0	COG2081@1|root,COG2081@2|Bacteria,2NPCB@2323|unclassified Bacteria	2|Bacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
YHH1_k127_5349661_4	768671.ThimaDRAFT_2673	0.0006163	49.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
YHH1_k127_5349661_1	945713.IALB_0806	2.355e-61	217.0	COG0231@1|root,COG0231@2|Bacteria	2|Bacteria	J	translation elongation factor activity	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YHH1_k127_5349661_2	945713.IALB_0807	1.105e-40	155.0	COG0511@1|root,COG0511@2|Bacteria	2|Bacteria	I	ligase activity, forming carbon-carbon bonds	accB	-	2.3.1.12,4.1.1.3	ko:K00627,ko:K01571,ko:K02160	ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00217,R00742,R02569	RC00004,RC00040,RC00367,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	iHN637.CLJU_RS20755	Biotin_lipoyl
YHH1_k127_5349661_0	945713.IALB_0808	3.321e-193	614.0	COG0439@1|root,COG0439@2|Bacteria	2|Bacteria	I	biotin carboxylase activity	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YHH1_k127_5349661_3	1313421.JHBV01000007_gene4179	3.607e-13	70.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1IT1E@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
YHH1_k127_536256_0	368407.Memar_1142	2.608e-98	328.0	COG0731@1|root,arCOG00953@2157|Archaea,2XUIN@28890|Euryarchaeota,2NB0A@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
YHH1_k127_536256_2	189426.PODO_29820	1.163e-13	85.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG4585@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,COG4585@2|Bacteria,1V96A@1239|Firmicutes,4HK2G@91061|Bacilli,274CT@186822|Paenibacillaceae	91061|Bacilli	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HisKA_3,Pkinase
YHH1_k127_536256_1	880073.Calab_3302	5.662e-60	212.0	COG0105@1|root,COG0105@2|Bacteria,2NPM5@2323|unclassified Bacteria	2|Bacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YHH1_k127_5369068_2	518766.Rmar_0979	1.777e-11	74.0	2F3KW@1|root,33WE4@2|Bacteria,4P383@976|Bacteroidetes,1FJD6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
YHH1_k127_5369068_1	445972.ANACOL_03961	4.578e-14	83.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,DUF262,HNH,HNH_4
YHH1_k127_5369068_3	1185876.BN8_04445	0.0001645	51.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,47M8A@768503|Cytophagia	976|Bacteroidetes	NU	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
YHH1_k127_5369068_0	352165.HMPREF7215_1925	1.98e-40	161.0	COG2304@1|root,COG2304@2|Bacteria,3TC87@508458|Synergistetes	508458|Synergistetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	VWA
YHH1_k127_5379068_2	411477.PARMER_01897	5.33e-17	83.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,2FNSY@200643|Bacteroidia,22WCY@171551|Porphyromonadaceae	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YHH1_k127_5379068_1	927658.AJUM01000011_gene1316	9.646e-29	129.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,2FP8Y@200643|Bacteroidia,3XJKZ@558415|Marinilabiliaceae	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5379068_0	1191523.MROS_0397	1.814e-78	269.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
YHH1_k127_5380134_1	395493.BegalDRAFT_1071	9.743e-83	295.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein conserved in bacteria	ycbB	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
YHH1_k127_5380134_0	1166018.FAES_1272	1.514e-113	374.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47N6X@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
YHH1_k127_538091_0	945713.IALB_1253	1.594e-107	359.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH1_k127_5387263_0	414684.RC1_0392	6e-208	666.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,2JQSF@204441|Rhodospirillales	204441|Rhodospirillales	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YHH1_k127_5412577_3	552811.Dehly_1009	1.301e-17	85.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,34CJQ@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH1_k127_5412577_4	519989.ECTPHS_14116	5.127e-05	46.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
YHH1_k127_5412577_2	1229172.JQFA01000002_gene4233	6.826e-38	147.0	COG3415@1|root,COG3415@2|Bacteria,1G802@1117|Cyanobacteria	1117|Cyanobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_32
YHH1_k127_5412577_0	485913.Krac_2355	1.043e-108	357.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2G9RC@200795|Chloroflexi	200795|Chloroflexi	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
YHH1_k127_5416264_1	1232410.KI421421_gene3694	1.533e-70	248.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,43SHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
YHH1_k127_5416264_0	1121381.JNIV01000033_gene2992	2.919e-81	280.0	COG0564@1|root,COG0564@2|Bacteria,1WM80@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
YHH1_k127_5416264_2	945713.IALB_1608	3.103e-29	119.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH1_k127_5419009_0	760568.Desku_1074	7.171e-223	698.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,25ZZD@186807|Peptococcaceae	186801|Clostridia	C	reductase alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH1_k127_5419009_1	1121423.JONT01000001_gene2038	1.517e-56	201.0	COG1146@1|root,COG1146@2|Bacteria,1V59C@1239|Firmicutes,24J64@186801|Clostridia,261U8@186807|Peptococcaceae	186801|Clostridia	C	reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_7,Fer4_9
YHH1_k127_5419009_2	760011.Spico_0217	8.583e-35	141.0	COG2344@1|root,COG2344@2|Bacteria,2J67B@203691|Spirochaetes	203691|Spirochaetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
YHH1_k127_5419009_3	747365.Thena_1368	4.971e-18	87.0	COG2920@1|root,COG2920@2|Bacteria,1V6WF@1239|Firmicutes,24JRH@186801|Clostridia,42GKQ@68295|Thermoanaerobacterales	186801|Clostridia	P	TIGRFAM sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
YHH1_k127_5461236_0	1191523.MROS_0329	9.831e-59	211.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	cwlM	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1
YHH1_k127_5461236_1	1499967.BAYZ01000073_gene2005	2.914e-39	155.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
YHH1_k127_5473071_1	945713.IALB_2894	1.856e-118	385.0	COG0396@1|root,COG0396@2|Bacteria	2|Bacteria	O	ATPase activity	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
YHH1_k127_5473071_0	945713.IALB_2893	1.868e-261	811.0	COG0719@1|root,COG0719@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	sufB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078	UPF0051
YHH1_k127_5488710_3	880073.Calab_2912	4.417e-54	196.0	COG2008@1|root,COG2008@2|Bacteria,2NNMP@2323|unclassified Bacteria	2|Bacteria	E	aromatic amino acid beta-eliminating lyase threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
YHH1_k127_5488710_0	517418.Ctha_0709	8.983e-89	316.0	COG0815@1|root,COG0815@2|Bacteria,1FDIC@1090|Chlorobi	1090|Chlorobi	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
YHH1_k127_5488710_5	1191523.MROS_1662	1.224e-42	162.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	-	R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
YHH1_k127_5488710_4	945713.IALB_2261	7.257e-45	170.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	yngC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH1_k127_5488710_2	411473.RUMCAL_02765	7.461e-57	203.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,3WITA@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
YHH1_k127_5488710_7	1158318.ATXC01000002_gene1668	3.328e-18	88.0	COG1254@1|root,COG1254@2|Bacteria,2G49Q@200783|Aquificae	200783|Aquificae	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YHH1_k127_5488710_6	391625.PPSIR1_04973	2.763e-41	171.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,43B01@68525|delta/epsilon subdivisions,2X6E4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YHH1_k127_5488710_1	861299.J421_1368	2.724e-60	225.0	COG0312@1|root,COG0312@2|Bacteria,1ZSYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
YHH1_k127_5488710_8	574087.Acear_1776	5.312e-17	83.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,3WBNJ@53433|Halanaerobiales	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_5492964_1	1198232.CYCME_1595	3.074e-36	146.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,1QVX1@1224|Proteobacteria,1RP9I@1236|Gammaproteobacteria,460NE@72273|Thiotrichales	72273|Thiotrichales	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
YHH1_k127_5492964_0	105559.Nwat_2048	3.314e-231	758.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales	135613|Chromatiales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH1_k127_5503819_0	926569.ANT_11560	4.478e-21	109.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH1_k127_5503819_1	1122918.KB907266_gene2125	7.765e-05	49.0	COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,4HD0M@91061|Bacilli,26QZG@186822|Paenibacillaceae	91061|Bacilli	D	Protein conserved in bacteria	yngK	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,GHL10
YHH1_k127_5508832_1	1047013.AQSP01000082_gene1136	6.432e-10	70.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2NQN1@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
YHH1_k127_5508832_0	1121396.KB892900_gene2075	4.269e-22	101.0	COG1520@1|root,COG2319@1|root,COG4249@1|root,COG1520@2|Bacteria,COG2319@2|Bacteria,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,42PEW@68525|delta/epsilon subdivisions,2WSC3@28221|Deltaproteobacteria,2MN4H@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TIR_2,WD40
YHH1_k127_5516188_3	945713.IALB_2356	1.535e-47	173.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	rnhA	-	3.1.26.4,4.1.1.44	ko:K01607,ko:K03469	ko00362,ko01100,ko01120,ko01220,ko03030,map00362,map01100,map01120,map01220,map03030	-	R03470	RC00938	ko00000,ko00001,ko01000,ko03032	-	-	-	CMD
YHH1_k127_5516188_1	247490.KSU1_C0602	2.615e-150	489.0	COG2133@1|root,COG2133@2|Bacteria,2IXAF@203682|Planctomycetes	203682|Planctomycetes	G	glucose sorbosone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	DUF1080,GSDH,SGL
YHH1_k127_5516188_2	264462.Bd1860	1.139e-113	387.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,42MT3@68525|delta/epsilon subdivisions,2MSPG@213481|Bdellovibrionales,2WIK5@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,HI0933_like,Pyr_redox_2
YHH1_k127_5516188_0	1191523.MROS_1228	1.143e-153	498.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_5516188_4	945713.IALB_1599	3.093e-29	119.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
YHH1_k127_5520757_2	1028803.GG9_0964	2.067e-56	199.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,1RYVB@1236|Gammaproteobacteria,1Y6Q9@135625|Pasteurellales	135625|Pasteurellales	P	Iron-storage protein	ftnB	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
YHH1_k127_5520757_1	1499967.BAYZ01000013_gene6442	8.793e-75	256.0	COG1014@1|root,COG1014@2|Bacteria,2NPBG@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	iorB	-	1.2.7.8	ko:K00179,ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
YHH1_k127_5520757_0	945713.IALB_2768	8.221e-229	721.0	COG4231@1|root,COG4231@2|Bacteria	2|Bacteria	C	indolepyruvate ferredoxin oxidoreductase activity	iorA	-	1.2.7.8	ko:K00179,ko:K08941	-	M00598	-	-	br01601,ko00000,ko00002,ko00194,ko01000	-	-	-	POR_N,TPP_enzyme_C
YHH1_k127_5530572_0	945713.IALB_0605	1.125e-72	254.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YHH1_k127_5530572_1	1121405.dsmv_1536	3.576e-37	149.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2WMWV@28221|Deltaproteobacteria,2MJH7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	cyclic nucleotide-binding	fnr-1	-	-	ko:K01420,ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YHH1_k127_5531684_0	1121104.AQXH01000001_gene1459	4.252e-89	327.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NRVM@976|Bacteroidetes,1IQDC@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
YHH1_k127_5531684_1	518766.Rmar_1866	2.529e-18	89.0	COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,1FISY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YHH1_k127_5555298_1	1121930.AQXG01000002_gene2126	3.797e-05	55.0	COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,1IPVJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
YHH1_k127_5555298_0	926569.ANT_13020	9.083e-33	132.0	COG0313@1|root,COG0313@2|Bacteria,2G6E3@200795|Chloroflexi	2|Bacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YHH1_k127_5563375_0	234267.Acid_5253	3.324e-35	142.0	COG0546@1|root,COG0546@2|Bacteria,3Y4RC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH1_k127_5563375_1	1173028.ANKO01000160_gene5048	1.016e-06	60.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G20P@1117|Cyanobacteria,1HAC0@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_11,TPR_2,TPR_8
YHH1_k127_5582670_0	945713.IALB_0300	4.067e-266	852.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N,Response_reg,SpoIIE
YHH1_k127_5587781_1	696747.NIES39_Q02700	3.561e-56	205.0	COG1085@1|root,COG1085@2|Bacteria,1G1CA@1117|Cyanobacteria,1H82Z@1150|Oscillatoriales	1117|Cyanobacteria	C	galactose-1-phosphate	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf,HIT
YHH1_k127_5587781_0	67356.KL575585_gene8187	2.864e-102	344.0	COG0076@1|root,COG0076@2|Bacteria	2|Bacteria	E	glutamate decarboxylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
YHH1_k127_5588192_3	504472.Slin_5305	3.312e-11	70.0	2BZRT@1|root,32R5J@2|Bacteria,4NR5S@976|Bacteroidetes,47QIR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5588192_0	1185876.BN8_06270	7.5e-103	349.0	COG0584@1|root,COG0584@2|Bacteria,4NJ13@976|Bacteroidetes,47MVH@768503|Cytophagia	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
YHH1_k127_5588192_2	1185876.BN8_06269	2.107e-22	107.0	29PN1@1|root,30AK7@2|Bacteria,4NPUT@976|Bacteroidetes,47PWG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5588192_1	1121931.AUHG01000018_gene1449	5.928e-56	214.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	ko:K02453,ko:K20543	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.55.3,3.A.15	-	-	TPR_12,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8,Transglut_core
YHH1_k127_5592858_0	883126.HMPREF9710_02963	9.278e-78	273.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,2VK2M@28216|Betaproteobacteria,47782@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
YHH1_k127_5592858_1	391038.Bphy_3371	6.845e-08	58.0	COG5113@1|root,COG3236@2|Bacteria,1QZQI@1224|Proteobacteria	1224|Proteobacteria	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
YHH1_k127_5621188_0	945713.IALB_0825	2.691e-41	160.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_5621188_1	1121930.AQXG01000023_gene1642	4.21e-23	107.0	COG0737@1|root,COG2374@1|root,COG0737@2|Bacteria,COG2374@2|Bacteria,4PPNB@976|Bacteroidetes,1IY1S@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	-	-	-	-	-	-	-	-	-	-	-	-	LTD
YHH1_k127_5628640_1	517418.Ctha_1724	9.046e-22	103.0	COG1404@1|root,COG1404@2|Bacteria,1FFAM@1090|Chlorobi	1090|Chlorobi	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH1_k127_5628640_0	945713.IALB_1579	3.864e-185	591.0	COG0034@1|root,COG0034@2|Bacteria	2|Bacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iSB619.SA_RS05225	GATase_6,GATase_7,Pribosyltran
YHH1_k127_5628640_2	1379698.RBG1_1C00001G1241	6.54e-10	62.0	COG0613@1|root,COG0613@2|Bacteria,2NPWD@2323|unclassified Bacteria	2|Bacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
YHH1_k127_563546_0	643648.Slip_1163	8.253e-240	771.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,42JMJ@68298|Syntrophomonadaceae	186801|Clostridia	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
YHH1_k127_563546_1	471223.GWCH70_1892	6.369e-73	256.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,4HAQA@91061|Bacilli,1WEKB@129337|Geobacillus	91061|Bacilli	P	Rhodanese Homology Domain	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
YHH1_k127_563546_2	247490.KSU1_C0449	6.365e-60	233.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
YHH1_k127_5641879_0	1121930.AQXG01000001_gene1524	2.57e-48	186.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1J03H@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5641879_1	945713.IALB_0488	1.632e-43	163.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
YHH1_k127_5646404_0	391596.PBAL39_01682	1.875e-27	125.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
YHH1_k127_5646404_1	518766.Rmar_2442	0.0002798	45.0	COG0737@1|root,COG0737@2|Bacteria,4PNDC@976|Bacteroidetes,1FJX0@1100069|Bacteroidetes Order II. Incertae sedis	2|Bacteria	F	pectinesterase activity	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	LRR_5,SBP_bac_8,TAT_signal
YHH1_k127_5666169_0	1382359.JIAL01000001_gene328	1.277e-201	647.0	COG0068@1|root,COG0068@2|Bacteria,3Y391@57723|Acidobacteria,2JKF7@204432|Acidobacteriia	204432|Acidobacteriia	O	HypF finger	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
YHH1_k127_5666169_2	1304883.KI912532_gene1055	1.27e-19	93.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,2VVZH@28216|Betaproteobacteria,2KX70@206389|Rhodocyclales	206389|Rhodocyclales	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
YHH1_k127_5666169_1	243164.DET1434	2.145e-64	225.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi,34CKT@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Hydrogenase formation hypA family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
YHH1_k127_5678845_0	1254432.SCE1572_04045	3.592e-20	93.0	COG3000@1|root,COG3000@2|Bacteria,1RJ68@1224|Proteobacteria	1224|Proteobacteria	I	hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
YHH1_k127_5678845_1	118168.MC7420_716	4.234e-17	92.0	COG0642@1|root,COG2199@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H9EM@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
YHH1_k127_5714143_0	304371.MCP_2389	3.021e-33	130.0	COG4870@1|root,arCOG03614@2157|Archaea,2XZI4@28890|Euryarchaeota,2NAH7@224756|Methanomicrobia	224756|Methanomicrobia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
YHH1_k127_5722186_1	1191523.MROS_0612	3.358e-32	132.0	COG0373@1|root,COG0373@2|Bacteria	2|Bacteria	H	glutamyl-tRNA reductase activity	hemA	GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040	1.2.1.70	ko:K02407,ko:K02492	ko00860,ko01100,ko01110,ko01120,ko02040,map00860,map01100,map01110,map01120,map02040	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000,ko02035	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
YHH1_k127_5722186_0	945713.IALB_0544	2.199e-52	195.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
YHH1_k127_5722186_2	518766.Rmar_2442	2.662e-05	48.0	COG0737@1|root,COG0737@2|Bacteria,4PNDC@976|Bacteroidetes,1FJX0@1100069|Bacteroidetes Order II. Incertae sedis	2|Bacteria	F	pectinesterase activity	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	LRR_5,SBP_bac_8,TAT_signal
YHH1_k127_5725359_1	1116472.MGMO_8c00900	1.352e-115	383.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,1RRE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH1_k127_5725359_3	517418.Ctha_2577	6.75e-113	373.0	COG3568@1|root,COG3568@2|Bacteria,1FEUT@1090|Chlorobi	1090|Chlorobi	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH1_k127_5725359_0	517418.Ctha_2091	6.355e-212	669.0	COG0001@1|root,COG0001@2|Bacteria,1FETV@1090|Chlorobi	1090|Chlorobi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH1_k127_5725359_2	517418.Ctha_2090	6.257e-114	378.0	COG3958@1|root,COG3958@2|Bacteria,1FDB9@1090|Chlorobi	2|Bacteria	G	PFAM Transketolase central region	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
YHH1_k127_5725359_4	517418.Ctha_2089	2.567e-31	124.0	COG3959@1|root,COG3959@2|Bacteria,1FEZ6@1090|Chlorobi	1090|Chlorobi	G	XFP N-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YHH1_k127_5772113_0	1313421.JHBV01000014_gene4037	8.188e-171	556.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPND@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	nagZ3	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
YHH1_k127_5772113_1	1123508.JH636442_gene4089	3.07e-100	339.0	COG3509@1|root,COG3509@2|Bacteria,2IYD5@203682|Planctomycetes	203682|Planctomycetes	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
YHH1_k127_5782233_0	1191523.MROS_2079	5.024e-20	104.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
YHH1_k127_5782233_1	485913.Krac_5383	6.405e-13	74.0	COG0346@1|root,COG0622@1|root,COG0346@2|Bacteria,COG0622@2|Bacteria,2G8MU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH1_k127_5783356_0	927658.AJUM01000042_gene1639	3.969e-136	441.0	COG2461@1|root,COG2461@2|Bacteria,4NJQA@976|Bacteroidetes,2FMK7@200643|Bacteroidia,3XKFV@558415|Marinilabiliaceae	976|Bacteroidetes	S	PAS domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF438,Hemerythrin,PAS_10
YHH1_k127_5783356_1	742766.HMPREF9455_01565	1.793e-30	128.0	COG4309@1|root,COG4309@2|Bacteria,4NQP0@976|Bacteroidetes,2FUI1@200643|Bacteroidia,22YII@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
YHH1_k127_5796104_2	518766.Rmar_1228	6.886e-09	65.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1FJ41@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	7TM-HD extracellular	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
YHH1_k127_5796104_1	1123274.KB899407_gene167	1.776e-19	99.0	COG0561@1|root,COG0561@2|Bacteria,2J5FZ@203691|Spirochaetes	203691|Spirochaetes	S	TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
YHH1_k127_5796104_0	309807.SRU_0371	6.686e-28	118.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1FIMH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH1_k127_5810800_0	945713.IALB_0635	7.711e-210	668.0	COG0178@1|root,COG0178@2|Bacteria	2|Bacteria	L	nucleotide-excision repair	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH1_k127_5810800_1	42565.FP66_13165	1.376e-09	64.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1XJR3@135619|Oceanospirillales	135619|Oceanospirillales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YHH1_k127_5834707_0	220664.PFL_2026	3.048e-33	140.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1QU2N@1224|Proteobacteria,1RYA1@1236|Gammaproteobacteria,1YT9S@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	VP1463	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glycos_transf_2,NAD_binding_8
YHH1_k127_5834707_2	224325.AF_0595	5.032e-09	69.0	COG2244@1|root,arCOG02209@2157|Archaea,2XZTW@28890|Euryarchaeota,246RI@183980|Archaeoglobi	183980|Archaeoglobi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
YHH1_k127_5834707_1	491916.RHECIAT_PC0000566	5.274e-23	110.0	COG0110@1|root,COG0110@2|Bacteria,1N6SQ@1224|Proteobacteria,2VF71@28211|Alphaproteobacteria,4BN7R@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YHH1_k127_5834707_3	1894.JOER01000032_gene6086	3.854e-08	63.0	COG5653@1|root,COG5653@2|Bacteria,2HCZ1@201174|Actinobacteria	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
YHH1_k127_5851696_0	945713.IALB_2244	2.409e-85	299.0	COG3174@1|root,COG3174@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
YHH1_k127_5851696_1	1396418.BATQ01000101_gene5457	9.611e-40	160.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_5851696_2	192952.MM_1377	1.804e-31	139.0	COG5607@1|root,arCOG05139@2157|Archaea,2Y7EP@28890|Euryarchaeota,2NA8G@224756|Methanomicrobia	224756|Methanomicrobia	F	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
YHH1_k127_5852776_0	1128427.KB904821_gene2484	4.648e-96	329.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G1M7@1117|Cyanobacteria,1H7YE@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,STAS
YHH1_k127_5852776_2	290512.Paes_1249	3.081e-37	146.0	COG1342@1|root,COG1342@2|Bacteria,1FEAH@1090|Chlorobi	1090|Chlorobi	S	Belongs to the UPF0251 family	-	-	-	ko:K06933	-	-	-	-	ko00000	-	-	-	DUF134
YHH1_k127_5852776_3	1191523.MROS_0498	6.001e-12	74.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
YHH1_k127_5852776_1	118168.MC7420_3902	1.056e-78	275.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1GPXH@1117|Cyanobacteria,1HI1A@1150|Oscillatoriales	1117|Cyanobacteria	T	T COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH1_k127_5853666_0	1191523.MROS_2504	4.104e-50	180.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	ytkL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
YHH1_k127_5853666_1	909663.KI867151_gene3130	3.529e-43	165.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WPQ1@28221|Deltaproteobacteria,2MRTY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH1_k127_5853666_2	1519464.HY22_10505	6.243e-22	104.0	2EEYB@1|root,338RQ@2|Bacteria,1FF1Q@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5855576_0	945713.IALB_1715	1.639e-06	62.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,F5_F8_type_C
YHH1_k127_586_0	1244869.H261_04640	2.432e-71	249.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2TSR6@28211|Alphaproteobacteria,2JRVG@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
YHH1_k127_586_1	517418.Ctha_2502	2.661e-49	183.0	COG1846@1|root,COG1846@2|Bacteria,1FF65@1090|Chlorobi	1090|Chlorobi	K	PFAM regulatory protein MarR	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
YHH1_k127_586_2	304371.MCP_0824	8.316e-09	59.0	COG4912@1|root,arCOG05122@2157|Archaea,2Y8HF@28890|Euryarchaeota	28890|Euryarchaeota	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YHH1_k127_5905782_0	1122182.KB903836_gene5058	1.691e-52	193.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4D90H@85008|Micromonosporales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
YHH1_k127_5905782_1	1410612.JNKO01000009_gene2095	3.018e-33	138.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
YHH1_k127_5913992_1	1191523.MROS_1860	1.192e-109	376.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,SSF,SpoIIE
YHH1_k127_5913992_0	445970.ALIPUT_01770	2.67e-142	465.0	COG2271@1|root,COG2271@2|Bacteria,4PKTC@976|Bacteroidetes,2G3HT@200643|Bacteroidia,22V02@171550|Rikenellaceae	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH1_k127_5913992_2	997884.HMPREF1068_01450	1.481e-09	62.0	2DRT8@1|root,33CYG@2|Bacteria,4PHKQ@976|Bacteroidetes,2FTAE@200643|Bacteroidia,4AREX@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	pqqD	-	-	-	-	-	-	-	-	-	-	-	PqqD
YHH1_k127_5939340_0	1408813.AYMG01000032_gene5238	8.851e-87	317.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,F5_F8_type_C,PKD
YHH1_k127_5943326_1	935836.JAEL01000007_gene2907	3.747e-09	68.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus	91061|Bacilli	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
YHH1_k127_5948715_1	644282.Deba_1142	1.375e-23	108.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
YHH1_k127_5948715_0	1191523.MROS_2436	4.837e-149	481.0	COG0468@1|root,COG0468@2|Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
YHH1_k127_5948715_3	36875.HQ29_08350	1.828e-05	56.0	2EEHA@1|root,338B4@2|Bacteria,4NWYM@976|Bacteroidetes,2FV34@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
YHH1_k127_5962536_3	1499967.BAYZ01000009_gene5344	4.22e-13	80.0	COG1470@1|root,COG2885@1|root,COG1470@2|Bacteria,COG2885@2|Bacteria,2NPWP@2323|unclassified Bacteria	2|Bacteria	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	DUF4384,DUF4625,OmpA,PEGA
YHH1_k127_5962536_0	945713.IALB_2190	2.166e-71	251.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
YHH1_k127_5962536_2	1519464.HY22_06715	9.417e-34	139.0	COG1729@1|root,COG1729@2|Bacteria,1FEBS@1090|Chlorobi	1090|Chlorobi	S	PFAM Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6
YHH1_k127_5962536_4	1150469.RSPPHO_02781	0.0001951	44.0	COG2165@1|root,COG2165@2|Bacteria,1PJ5F@1224|Proteobacteria,2VC7I@28211|Alphaproteobacteria,2JY2W@204441|Rhodospirillales	204441|Rhodospirillales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5962536_1	398767.Glov_3342	5.722e-44	166.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria,43TZB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH1_k127_5965200_2	1121930.AQXG01000012_gene3237	9.533e-08	64.0	COG1404@1|root,COG1404@2|Bacteria,4NVH2@976|Bacteroidetes,1IURU@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5965200_1	404589.Anae109_1788	8.932e-08	59.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,2YZVB@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH1_k127_5975049_0	518766.Rmar_1316	8.643e-102	340.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1FJIC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Polysaccharide biosynthesis protein	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH1_k127_5975049_1	945713.IALB_0750	4.181e-71	253.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
YHH1_k127_5979059_1	1379270.AUXF01000001_gene1954	1.947e-43	181.0	COG0457@1|root,COG0457@2|Bacteria	1379270.AUXF01000001_gene1954|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5979059_0	945713.IALB_2958	1.012e-85	298.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,SLH
YHH1_k127_5979059_2	518766.Rmar_2726	0.0003134	46.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5993817_0	1519464.HY22_04375	3.116e-91	314.0	COG5448@1|root,COG5448@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
YHH1_k127_5993817_1	485915.Dret_1332	3.145e-58	206.0	COG0204@1|root,COG0204@2|Bacteria,1PY44@1224|Proteobacteria,42NR4@68525|delta/epsilon subdivisions,2WKKQ@28221|Deltaproteobacteria,2MAGC@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH1_k127_5996144_2	243231.GSU1326	2.593e-45	168.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,43TAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YHH1_k127_5996144_0	1089548.KI783301_gene3330	2.869e-66	233.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,3WE7W@539002|Bacillales incertae sedis	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
YHH1_k127_5996144_1	1499967.BAYZ01000065_gene6110	1.646e-59	212.0	COG1238@1|root,COG1238@2|Bacteria,2NR6R@2323|unclassified Bacteria	2|Bacteria	S	SNARE associated Golgi protein	MA20_20865	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
YHH1_k127_6005721_0	1453498.LG45_15340	2.141e-05	58.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWPC@117743|Flavobacteriia,2NUG7@237|Flavobacterium	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
YHH1_k127_6006246_0	945713.IALB_2872	1.151e-165	527.0	COG1048@1|root,COG1048@2|Bacteria	2|Bacteria	C	aconitate hydratase activity	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH1_k127_6006246_1	1121104.AQXH01000004_gene74	5.071e-46	181.0	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1IT8Y@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
YHH1_k127_6006246_2	269799.Gmet_1068	3.505e-09	66.0	COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,42SBY@68525|delta/epsilon subdivisions,2WPSK@28221|Deltaproteobacteria,43V9B@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6010824_0	1265505.ATUG01000001_gene4678	1.432e-47	188.0	COG0584@1|root,COG1409@1|root,COG0584@2|Bacteria,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GDPD_2,Metallophos,Pur_ac_phosph_N
YHH1_k127_6010824_1	582744.Msip34_2211	1.394e-42	165.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KKZP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
YHH1_k127_6038254_0	1191523.MROS_0475	7.969e-195	632.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
YHH1_k127_6039993_1	517418.Ctha_2526	8.402e-26	114.0	COG0382@1|root,COG0382@2|Bacteria,1FEYJ@1090|Chlorobi	1090|Chlorobi	H	UbiA prenyltransferase family	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
YHH1_k127_6039993_0	397945.Aave_1837	4.21e-57	214.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,4AAT9@80864|Comamonadaceae	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH1_k127_6039993_2	596151.DesfrDRAFT_0910	7.959e-22	101.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,42VES@68525|delta/epsilon subdivisions,2WRSC@28221|Deltaproteobacteria,2MCFG@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
YHH1_k127_6039993_4	63737.Npun_R1791	0.0002835	49.0	COG4244@1|root,COG4244@2|Bacteria,1G5BC@1117|Cyanobacteria,1HRYM@1161|Nostocales	1117|Cyanobacteria	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
YHH1_k127_6039993_3	1283299.AUKG01000001_gene1400	2.3e-10	69.0	COG4447@1|root,COG4447@2|Bacteria,2HPY1@201174|Actinobacteria,4CRD8@84995|Rubrobacteria	84995|Rubrobacteria	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_6050453_0	204669.Acid345_2058	0.0002292	53.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YHH1_k127_6054187_1	945713.IALB_1789	4.099e-11	74.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_6054187_2	243231.GSU1945	5.781e-08	64.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,1Q4PP@1224|Proteobacteria,42YRG@68525|delta/epsilon subdivisions,2WUJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3
YHH1_k127_6054187_0	755732.Fluta_1682	9.662e-63	232.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PI0A@976|Bacteroidetes,1IMVQ@117743|Flavobacteriia,2PBY2@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH1_k127_6085167_2	945713.IALB_2285	4.861e-17	83.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH1_k127_6085167_1	243231.GSU2791	4.665e-42	157.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the UPF0145 family	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
YHH1_k127_6085167_0	945713.IALB_2314	1.702e-54	211.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_6085482_4	1122135.KB893146_gene1436	3.151e-14	74.0	2EAYI@1|root,334ZG@2|Bacteria,1N8W1@1224|Proteobacteria,2UYBX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6085482_2	435908.IDSA_04820	4.068e-26	111.0	COG3809@1|root,COG3809@2|Bacteria,1N6ZY@1224|Proteobacteria,1SEM4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
YHH1_k127_6085482_0	1267535.KB906767_gene1959	2.507e-52	192.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_6085482_1	639030.JHVA01000001_gene970	1.6e-41	177.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480,ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
YHH1_k127_6085482_3	1237149.C900_03388	5.906e-22	113.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NQHU@976|Bacteroidetes,47R06@768503|Cytophagia	1237149.C900_03388|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6092956_1	1391646.AVSU01000051_gene1753	2.163e-152	499.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,25QPF@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH1_k127_6092956_3	880073.Calab_0106	1.146e-38	149.0	2E8AI@1|root,332PD@2|Bacteria,2NRHQ@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6092956_4	886293.Sinac_6813	1.591e-22	102.0	COG0319@1|root,COG0319@2|Bacteria,2J0MV@203682|Planctomycetes	203682|Planctomycetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
YHH1_k127_6092956_5	880073.Calab_0883	1.363e-19	94.0	COG2922@1|root,COG2922@2|Bacteria	2|Bacteria	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
YHH1_k127_6092956_0	1125863.JAFN01000001_gene2082	5.847e-238	758.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
YHH1_k127_6092956_2	880073.Calab_0885	1.138e-65	235.0	COG4974@1|root,COG4974@2|Bacteria,2NP4H@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase, N-terminal SAM-like domain	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH1_k127_6099349_0	1519464.HY22_12840	2.962e-59	231.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25,Propeptide_C25
YHH1_k127_6099349_1	331678.Cphamn1_0888	1.633e-12	72.0	293MG@1|root,2ZR3A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6104065_1	1220589.CD32_22975	2.355e-20	104.0	COG0714@1|root,COG0714@2|Bacteria,1UXAG@1239|Firmicutes,4HC1E@91061|Bacilli	91061|Bacilli	S	AAA domain (dynein-related subfamily)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_5
YHH1_k127_6104065_0	1121104.AQXH01000005_gene233	4.793e-76	287.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1IPPH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
YHH1_k127_6123703_0	1313421.JHBV01000030_gene2160	1.781e-12	80.0	COG1572@1|root,COG2911@1|root,COG2931@1|root,COG3391@1|root,COG3897@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,COG3897@2|Bacteria,4PN0F@976|Bacteroidetes,1IWTM@117747|Sphingobacteriia	976|Bacteroidetes	P	major pilin protein fima	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Laminin_G_3
YHH1_k127_6145745_0	518766.Rmar_0925	7.962e-130	440.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
YHH1_k127_6145745_1	1519464.HY22_06660	6.301e-07	60.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,MAM,Sortilin-Vps10,TIG,fn3
YHH1_k127_6145808_2	469618.FVAG_00037	7.56e-23	103.0	29IC7@1|root,3059E@2|Bacteria,37AAR@32066|Fusobacteria	32066|Fusobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6145808_0	443143.GM18_2154	3.308e-80	276.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,42MAN@68525|delta/epsilon subdivisions,2WJBB@28221|Deltaproteobacteria,43S2Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM tRNA synthetase, class II (D, K and N)	genX	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
YHH1_k127_6145808_1	313628.LNTAR_23689	2.002e-58	207.0	COG0231@1|root,COG0231@2|Bacteria	2|Bacteria	J	translation elongation factor activity	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YHH1_k127_6154857_0	1191523.MROS_1743	5.165e-129	422.0	COG0272@1|root,COG0272@2|Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972,ko:K10754	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	M00289,M00295	R00382	RC00005	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YHH1_k127_6154857_2	1191523.MROS_1744	3.378e-14	76.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
YHH1_k127_6154857_1	861299.J421_3608	5.676e-49	179.0	COG0591@1|root,COG0591@2|Bacteria,1ZTEB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH1_k127_6204515_1	880072.Desac_2104	5.25e-110	372.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,2MSIS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YHH1_k127_6204515_0	240016.ABIZ01000001_gene1718	7.985e-135	447.0	COG1055@1|root,COG1055@2|Bacteria,46S6A@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
YHH1_k127_6204515_2	1232410.KI421424_gene1793	9.582e-16	79.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,43TUC@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
YHH1_k127_6206180_1	765420.OSCT_2237	1.381e-22	99.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH1_k127_6206180_0	485913.Krac_5376	6.89e-95	324.0	COG4552@1|root,COG4552@2|Bacteria,2G9TN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
YHH1_k127_6206180_2	243090.RB12409	3.539e-12	69.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IXKI@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA,VWA_3
YHH1_k127_6215468_1	880073.Calab_2082	5.188e-07	54.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
YHH1_k127_6215468_0	1235803.C825_00972	1.391e-28	134.0	COG5652@1|root,COG5652@2|Bacteria,4NIE7@976|Bacteroidetes,2FQJV@200643|Bacteroidia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510	4.2.2.7,4.2.2.8	ko:K19051	-	-	-	-	ko00000,ko01000	-	PL21	-	DUF4962,Hepar_II_III
YHH1_k127_6232459_0	1111730.ATTM01000002_gene1145	1.106e-104	351.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,1HYAD@117743|Flavobacteriia,2NU8F@237|Flavobacterium	976|Bacteroidetes	C	NADH flavin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
YHH1_k127_6232459_1	1191523.MROS_1731	0.0004367	49.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YHH1_k127_6254873_2	1191523.MROS_2552	6.286e-47	181.0	COG1386@1|root,COG1386@2|Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
YHH1_k127_6254873_1	945713.IALB_1557	2.958e-58	214.0	COG1354@1|root,COG1354@2|Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
YHH1_k127_6254873_0	1191523.MROS_2554	8.423e-150	480.0	COG0180@1|root,COG0180@2|Bacteria	2|Bacteria	J	Tryptophanyl-tRNA synthetase	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH1_k127_6254873_3	518766.Rmar_1583	3.708e-17	81.0	COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,1FJ89@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
YHH1_k127_6267646_0	945713.IALB_1615	4.49e-90	301.0	COG1158@1|root,COG1158@2|Bacteria	2|Bacteria	K	DNA-templated transcription, termination	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
YHH1_k127_6267646_1	1121335.Clst_0640	1.29e-18	94.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGH0@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH1_k127_6316724_0	945713.IALB_1999	3.287e-77	269.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
YHH1_k127_6316724_1	671143.DAMO_2633	4.135e-68	246.0	COG1253@1|root,COG1253@2|Bacteria,2NP04@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	ytfL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03699,ko:K06189	-	-	-	-	ko00000,ko02000,ko02042	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21,TerC
YHH1_k127_6317792_4	1380390.JIAT01000013_gene297	2.149e-17	89.0	COG0823@1|root,COG0823@2|Bacteria,2I40M@201174|Actinobacteria,4CRKD@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6317792_2	1191523.MROS_2761	7.738e-102	344.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,MFS_1_like,Sugar_tr
YHH1_k127_6317792_1	945713.IALB_2247	1.147e-106	359.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
YHH1_k127_6317792_0	945713.IALB_0292	5.112e-108	372.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
YHH1_k127_6317792_3	580332.Slit_2572	1.646e-39	149.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6347551_2	868595.Desca_1426	8.471e-47	182.0	COG0451@1|root,COG0451@2|Bacteria,1UZR1@1239|Firmicutes,24DWP@186801|Clostridia	186801|Clostridia	GM	NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YHH1_k127_6347551_0	56780.SYN_02648	9.088e-135	438.0	COG0451@1|root,COG0451@2|Bacteria,1MV73@1224|Proteobacteria,42N2Z@68525|delta/epsilon subdivisions,2WIVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH1_k127_6347551_1	290397.Adeh_4297	1.667e-106	351.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MCW@68525|delta/epsilon subdivisions,2WIYK@28221|Deltaproteobacteria,2YZY8@29|Myxococcales	28221|Deltaproteobacteria	JM	Nucleotidyl transferase	ddhA	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
YHH1_k127_6357960_0	452637.Oter_4531	8.114e-103	343.0	COG4805@1|root,COG4805@2|Bacteria,46T5D@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
YHH1_k127_6357960_1	385682.AFSL01000063_gene1514	4.483e-65	235.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,4NIT0@976|Bacteroidetes,2FMEM@200643|Bacteroidia,3XJI6@558415|Marinilabiliaceae	976|Bacteroidetes	S	P-loop ATPase protein family	-	-	-	-	-	-	-	-	-	-	-	-	APH,ATP_bind_2
YHH1_k127_6374309_1	945713.IALB_0754	1.752e-46	170.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YHH1_k127_6374309_0	1191523.MROS_0290	3.316e-266	844.0	COG0587@1|root,COG0587@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
YHH1_k127_637799_2	313628.LNTAR_09364	5.929e-91	307.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH1_k127_637799_1	313628.LNTAR_09364	8.625e-95	316.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH1_k127_6383937_0	555088.DealDRAFT_0356	1.266e-39	163.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,42JHW@68298|Syntrophomonadaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH1_k127_6383937_1	518766.Rmar_2252	8.054e-10	63.0	COG0457@1|root,COG0457@2|Bacteria,4NXQQ@976|Bacteroidetes,1FJDW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6407152_0	880073.Calab_2983	5.899e-246	772.0	COG0542@1|root,COG0542@2|Bacteria,2NNNE@2323|unclassified Bacteria	2|Bacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH1_k127_6424181_2	309801.trd_1474	1.164e-06	51.0	COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi,27Y3E@189775|Thermomicrobia	189775|Thermomicrobia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YHH1_k127_6424181_0	880073.Calab_2482	9.254e-131	431.0	COG0534@1|root,COG0534@2|Bacteria,2NPFE@2323|unclassified Bacteria	2|Bacteria	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	ANKH,MatE
YHH1_k127_6424181_1	1121438.JNJA01000006_gene244	4.091e-19	96.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1RCHY@1224|Proteobacteria,42R1G@68525|delta/epsilon subdivisions,2WMR7@28221|Deltaproteobacteria,2M83U@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
YHH1_k127_6429407_2	746697.Aeqsu_2083	0.0001444	49.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Sortilin-Vps10
YHH1_k127_6429407_1	1313421.JHBV01000020_gene5237	1.214e-21	112.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,4NIM1@976|Bacteroidetes	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_M43,Reprolysin_3
YHH1_k127_6429407_0	1122939.ATUD01000001_gene577	9.506e-66	256.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6505768_0	1519464.HY22_04590	3.028e-272	854.0	COG0058@1|root,COG0058@2|Bacteria,1FD8Y@1090|Chlorobi	1090|Chlorobi	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
YHH1_k127_6505768_2	1123367.C666_08075	7.138e-07	53.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,2VVVU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
YHH1_k127_6505768_1	391625.PPSIR1_36707	1.381e-39	150.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YHH1_k127_6522708_0	1158292.JPOE01000002_gene2595	8.65e-74	249.0	COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,2VJG9@28216|Betaproteobacteria,1KN7Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Helix-turn-helix domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
YHH1_k127_6531769_1	945713.IALB_1848	7.932e-49	188.0	COG0772@1|root,COG0772@2|Bacteria	2|Bacteria	D	peptidoglycan glycosyltransferase activity	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
YHH1_k127_6531769_0	290512.Paes_0709	9.122e-79	272.0	COG0768@1|root,COG0768@2|Bacteria,1FD7D@1090|Chlorobi	1090|Chlorobi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
YHH1_k127_6534298_0	945713.IALB_0486	9.908e-193	621.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_6545273_0	443143.GM18_0306	1.848e-67	261.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,43UFI@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains Cache_1, HAMP, PAS, PAS	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_9,dCache_1
YHH1_k127_6545273_1	504472.Slin_4824	3.708e-30	140.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NHSC@976|Bacteroidetes,47NEM@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,SpoIIE,Y_Y_Y
YHH1_k127_6550162_3	1168034.FH5T_20565	1.55e-53	193.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,2FPGA@200643|Bacteroidia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
YHH1_k127_6550162_0	1125863.JAFN01000001_gene2599	8.428e-68	240.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WPQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
YHH1_k127_6550162_1	880072.Desac_0143	2.193e-64	236.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
YHH1_k127_6550162_2	477974.Daud_0833	8.098e-60	218.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,2629U@186807|Peptococcaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
YHH1_k127_6564868_0	945713.IALB_2371	4.699e-292	905.0	COG0481@1|root,COG0481@2|Bacteria	2|Bacteria	M	GTPase activity	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YHH1_k127_6564868_1	945713.IALB_2231	5.951e-71	249.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YHH1_k127_6564868_2	331678.Cphamn1_0902	3.24e-30	128.0	COG0681@1|root,COG0681@2|Bacteria,1FDIZ@1090|Chlorobi	1090|Chlorobi	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YHH1_k127_6574834_2	945713.IALB_0799	3.351e-18	92.0	COG0457@1|root,COG0457@2|Bacteria	945713.IALB_0799|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6574834_1	518766.Rmar_1508	1.971e-49	184.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,1FJAU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
YHH1_k127_6574834_0	945713.IALB_1683	9.573e-71	251.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YHH1_k127_6574834_3	324925.Ppha_0498	4.924e-07	60.0	COG1555@1|root,COG1555@2|Bacteria,1FD6R@1090|Chlorobi	1090|Chlorobi	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
YHH1_k127_6576543_1	748280.NH8B_1063	8.408e-126	410.0	COG0758@1|root,COG3266@1|root,COG0758@2|Bacteria,COG3266@2|Bacteria,1Q7YP@1224|Proteobacteria,2VQH2@28216|Betaproteobacteria	28216|Betaproteobacteria	LU	DNA recombination-mediator protein A	-	-	-	-	-	-	-	-	-	-	-	-	DNA_processg_A
YHH1_k127_6576543_0	228410.NE2520	0.0	1057.0	COG0514@1|root,COG1040@1|root,COG0514@2|Bacteria,COG1040@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,3724T@32003|Nitrosomonadales	28216|Betaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
YHH1_k127_6576543_2	485917.Phep_1872	1.31e-64	225.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1IP3U@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH1_k127_6581922_0	1408433.JHXV01000017_gene1551	2.426e-75	262.0	COG1680@1|root,COG1680@2|Bacteria,4NGND@976|Bacteroidetes,1HWQE@117743|Flavobacteriia,2PA9A@246874|Cryomorphaceae	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH1_k127_6609414_1	555088.DealDRAFT_1008	2.335e-35	136.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,42K0N@68298|Syntrophomonadaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YHH1_k127_6609414_2	880070.Cycma_2148	1.959e-31	125.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,47R7R@768503|Cytophagia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
YHH1_k127_6609414_0	1519464.HY22_02350	1.37e-44	182.0	COG0457@1|root,COG0457@2|Bacteria,1FDVB@1090|Chlorobi	1090|Chlorobi	S	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
YHH1_k127_6609414_3	1191523.MROS_2056	2.466e-23	109.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	DUF4292,LolA,LolA_like
YHH1_k127_6612062_0	9483.ENSCJAP00000004746	1.605e-07	62.0	COG4886@1|root,KOG0619@2759|Eukaryota,38C0V@33154|Opisthokonta,3BJNH@33208|Metazoa,3CY4A@33213|Bilateria,486GS@7711|Chordata,499UZ@7742|Vertebrata,3JD1K@40674|Mammalia,35B42@314146|Euarchontoglires,4MFWU@9443|Primates	33208|Metazoa	S	Leucine Rich repeats (2 copies)	LRRIQ4	GO:0003674,GO:0005215,GO:0005216,GO:0005225,GO:0005253,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0007154,GO:0007165,GO:0008150,GO:0008509,GO:0009987,GO:0015075,GO:0015103,GO:0015267,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0023052,GO:0031224,GO:0032991,GO:0034220,GO:0034702,GO:0044424,GO:0044425,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0065007,GO:0071944,GO:0098656,GO:0098796,GO:1902495,GO:1990351	-	-	-	-	-	-	-	-	-	-	IQ,LRR_1,LRR_4,LRR_8
YHH1_k127_6612062_1	1227739.Hsw_2605	4.284e-06	53.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,47MX4@768503|Cytophagia	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	npr	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C,fn3
YHH1_k127_6622164_1	880073.Calab_0829	3.497e-09	69.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane
YHH1_k127_6622164_0	1500890.JQNL01000001_gene301	3.434e-27	118.0	2EJ52@1|root,33CW9@2|Bacteria,1PD05@1224|Proteobacteria,1SY6A@1236|Gammaproteobacteria,1X79D@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6623568_0	1408473.JHXO01000005_gene1497	1.275e-60	212.0	COG2006@1|root,COG2006@2|Bacteria,4NM3M@976|Bacteroidetes,2FQJA@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YHH1_k127_6623568_3	1408473.JHXO01000005_gene1498	6.429e-18	94.0	2BYKN@1|root,3396X@2|Bacteria,4NWPU@976|Bacteroidetes,2FVDW@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6623568_4	945713.IALB_0485	4.381e-16	83.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
YHH1_k127_6623568_2	1191523.MROS_1164	7.823e-20	91.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH1_k127_6623568_5	1408473.JHXO01000013_gene541	5.059e-10	63.0	2DSUK@1|root,33HGQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6623568_1	945713.IALB_2955	1.152e-48	176.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
YHH1_k127_6643549_1	443143.GM18_0306	1.227e-69	264.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,43UFI@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains Cache_1, HAMP, PAS, PAS	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_9,dCache_1
YHH1_k127_6643549_2	1279009.ADICEAN_00031	1.994e-07	54.0	COG2230@1|root,COG2230@2|Bacteria,4NHFT@976|Bacteroidetes	976|Bacteroidetes	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
YHH1_k127_6643549_3	686578.AFFX01000005_gene4245	0.0002146	48.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	type I restriction-modification system	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
YHH1_k127_6643549_0	324057.Pjdr2_0584	7.292e-109	364.0	COG2220@1|root,COG2220@2|Bacteria,1TRRP@1239|Firmicutes,4HBBS@91061|Bacilli,275MW@186822|Paenibacillaceae	91061|Bacilli	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
YHH1_k127_6648520_0	682795.AciX8_0629	3.633e-102	340.0	COG3185@1|root,COG3185@2|Bacteria,3Y2ST@57723|Acidobacteria,2JISR@204432|Acidobacteriia	204432|Acidobacteriia	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
YHH1_k127_6648520_1	309803.CTN_0163	5.669e-45	169.0	COG2110@1|root,COG2256@1|root,COG2110@2|Bacteria,COG2256@2|Bacteria,2GC7M@200918|Thermotogae	200918|Thermotogae	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,Macro,MgsA_C,RuvB_N
YHH1_k127_6648520_3	1191523.MROS_1767	2.372e-14	74.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
YHH1_k127_6648520_2	269799.Gmet_1839	8.676e-22	95.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,42MAN@68525|delta/epsilon subdivisions,2WJBB@28221|Deltaproteobacteria,43S2Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM tRNA synthetase, class II (D, K and N)	genX	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
YHH1_k127_6670312_1	1267535.KB906767_gene1958	2.63e-38	162.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480,ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
YHH1_k127_6670312_0	1267535.KB906767_gene1959	4.621e-49	185.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_6670312_2	1265503.KB905176_gene4099	5.18e-20	94.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T2D4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF,HATPase_c,HisKA,Response_reg
YHH1_k127_6671016_0	909663.KI867151_gene2965	7.14e-241	754.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MR61@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, NADH-binding	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
YHH1_k127_6671016_1	909663.KI867151_gene2964	2.669e-57	207.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,43DNM@68525|delta/epsilon subdivisions,2X6M5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
YHH1_k127_6698460_0	945713.IALB_2277	5.401e-176	560.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YHH1_k127_6698460_1	929556.Solca_1376	2.001e-121	397.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1IP70@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
YHH1_k127_6698460_2	1297742.A176_00759	1.346e-30	121.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUF5@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
YHH1_k127_6699570_0	1191523.MROS_1089	3.31e-128	428.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64,VWA
YHH1_k127_6708286_1	1190603.AJYD01000015_gene896	5.611e-07	61.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,1SBRE@1236|Gammaproteobacteria,1Y2RA@135623|Vibrionales	135623|Vibrionales	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
YHH1_k127_6708286_2	671143.DAMO_2996	2.534e-05	52.0	COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YHH1_k127_6714998_0	313596.RB2501_06815	7.102e-204	657.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1HWN4@117743|Flavobacteriia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
YHH1_k127_6715227_1	292563.Cyast_0135	2.315e-17	85.0	COG4445@1|root,COG4445@2|Bacteria,1G1MM@1117|Cyanobacteria	1117|Cyanobacteria	FJ	Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
YHH1_k127_6715227_0	1499967.BAYZ01000074_gene2080	1.032e-24	105.0	COG1853@1|root,COG1853@2|Bacteria,2NQXP@2323|unclassified Bacteria	2|Bacteria	S	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	actI	-	1.5.1.36	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	-	R02698,R03299,R05705,R09748,R09750	RC00046,RC00126	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
YHH1_k127_6741967_0	1191523.MROS_0675	1.277e-84	282.0	COG0191@1|root,COG0191@2|Bacteria	2|Bacteria	G	fructose-bisphosphate aldolase activity	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
YHH1_k127_6741967_1	945713.IALB_0188	3.284e-16	91.0	COG1649@1|root,COG4733@1|root,COG1649@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	J	-	3.2.1.11,3.2.1.18,3.2.1.35	ko:K01186,ko:K01197,ko:K05988,ko:K11931,ko:K21449	ko00500,ko00511,ko00531,ko00600,ko01100,ko02026,ko04142,map00500,map00511,map00531,map00600,map01100,map02026,map04142	M00076,M00077	R04018,R07824,R07825,R10905,R11309	RC00028,RC00077	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02000,ko02042	1.B.40.2	GH33,GH66	-	DUF1983,DUF3672,Phage-tail_3
YHH1_k127_6744187_1	517417.Cpar_1867	3.995e-57	206.0	COG5009@1|root,COG5009@2|Bacteria,1FDR2@1090|Chlorobi	1090|Chlorobi	M	TIGRFAM penicillin-binding protein, 1A family	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
YHH1_k127_6744187_0	880073.Calab_1553	1.568e-59	216.0	COG2908@1|root,COG2908@2|Bacteria,2NPKW@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
YHH1_k127_6744187_2	118168.MC7420_4492	8.608e-10	67.0	COG3210@1|root,COG4935@1|root,COG3210@2|Bacteria,COG4935@2|Bacteria,1G0EK@1117|Cyanobacteria	1117|Cyanobacteria	U	TIGRFAM filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act,P_proprotein
YHH1_k127_6746313_0	1121930.AQXG01000011_gene1763	2.678e-112	381.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.50	ko:K01337,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4397,Peptidase_S8,Trypsin_2
YHH1_k127_6746313_1	1168034.FH5T_14800	2.236e-63	222.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,2FTA9@200643|Bacteroidia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
YHH1_k127_6778265_0	945713.IALB_2273	1.471e-70	243.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
YHH1_k127_6778265_5	1121918.ARWE01000001_gene3055	1.805e-41	164.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,42R0Q@68525|delta/epsilon subdivisions,2WN87@28221|Deltaproteobacteria,43S55@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
YHH1_k127_6778265_2	319225.Plut_1495	1.067e-59	217.0	COG0388@1|root,COG0388@2|Bacteria,1FDC4@1090|Chlorobi	1090|Chlorobi	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
YHH1_k127_6778265_4	945713.IALB_3077	4.333e-50	190.0	COG4105@1|root,COG4105@2|Bacteria	2|Bacteria	S	cell envelope organization	yfiO	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
YHH1_k127_6778265_3	945713.IALB_3078	1.634e-52	194.0	COG1607@1|root,COG1607@2|Bacteria	2|Bacteria	I	acyl-coa hydrolase	ykhA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	3.1.2.20	ko:K01073	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
YHH1_k127_6778265_1	1191523.MROS_1623	1.238e-64	243.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YHH1_k127_6778265_6	945713.IALB_3080	7.303e-05	52.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YHH1_k127_6794444_1	706587.Desti_0293	2.598e-38	148.0	COG1633@1|root,COG1633@2|Bacteria,1N4PW@1224|Proteobacteria,42UZG@68525|delta/epsilon subdivisions,2WNGQ@28221|Deltaproteobacteria,2MS9U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YHH1_k127_6794444_0	909663.KI867150_gene397	5.285e-195	615.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MREN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
YHH1_k127_6805760_0	945713.IALB_0332	8.944e-210	672.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
YHH1_k127_6825500_2	518766.Rmar_1813	1.044e-102	355.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,1FIXN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycogen debranching enzyme, glucanotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
YHH1_k127_6825500_4	35754.JNYJ01000036_gene3601	6.216e-19	101.0	COG1470@1|root,COG3250@1|root,COG1470@2|Bacteria,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4DJC4@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH1_k127_6825500_3	391625.PPSIR1_33119	2.969e-69	242.0	COG0778@1|root,COG0778@2|Bacteria,1PEI0@1224|Proteobacteria,43A62@68525|delta/epsilon subdivisions,2X9UY@28221|Deltaproteobacteria,2Z2MI@29|Myxococcales	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
YHH1_k127_6825500_0	357808.RoseRS_1829	1.066e-160	514.0	COG0205@1|root,COG0205@2|Bacteria,2G6CJ@200795|Chloroflexi,374WW@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
YHH1_k127_6825500_1	1232410.KI421422_gene2000	6.761e-113	376.0	COG0475@1|root,COG1762@1|root,COG0475@2|Bacteria,COG1762@2|Bacteria,1MVGV@1224|Proteobacteria,42WJ6@68525|delta/epsilon subdivisions,2X9V9@28221|Deltaproteobacteria,43V8V@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YHH1_k127_6841847_3	1031711.RSPO_c02746	0.0003798	44.0	COG4659@1|root,COG4659@2|Bacteria,1RFGW@1224|Proteobacteria,2VTI7@28216|Betaproteobacteria,1K7BS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
YHH1_k127_6841847_2	1191523.MROS_1945	1.134e-22	106.0	2CCRG@1|root,30F34@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6841847_0	880073.Calab_1111	3.571e-102	365.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
YHH1_k127_6841847_1	945713.IALB_0988	1.098e-56	199.0	COG2978@1|root,COG2978@2|Bacteria	2|Bacteria	H	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity	ydaH	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
YHH1_k127_6867644_0	1121403.AUCV01000001_gene828	1.355e-201	640.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,2MIE2@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
YHH1_k127_687946_0	471854.Dfer_3542	1.383e-75	276.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,47MDC@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,MG1,Thiol-ester_cl
YHH1_k127_6883348_3	1415754.JQMK01000002_gene2084	6.293e-32	126.0	COG2944@1|root,COG2944@2|Bacteria,1RK75@1224|Proteobacteria,1S96V@1236|Gammaproteobacteria,468X4@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	MqsA_antitoxin
YHH1_k127_6883348_2	1191523.MROS_0293	1.568e-38	148.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
YHH1_k127_6883348_1	1125863.JAFN01000001_gene352	2.484e-137	446.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
YHH1_k127_6883348_0	1207063.P24_05962	6.286e-236	741.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,2JQ9C@204441|Rhodospirillales	204441|Rhodospirillales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YHH1_k127_6887072_0	945713.IALB_2675	8.841e-82	279.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1
YHH1_k127_6887072_2	1121930.AQXG01000002_gene2150	8.578e-17	94.0	COG0737@1|root,COG1649@1|root,COG0737@2|Bacteria,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,1IQ63@117747|Sphingobacteriia	976|Bacteroidetes	F	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
YHH1_k127_6887072_1	1121272.KB903261_gene5930	1.764e-42	173.0	COG3227@1|root,COG4447@1|root,COG3227@2|Bacteria,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria,4DC47@85008|Micromonosporales	201174|Actinobacteria	E	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
YHH1_k127_6895539_0	517418.Ctha_2039	1.294e-38	156.0	COG0457@1|root,COG0457@2|Bacteria,1FF1J@1090|Chlorobi	1090|Chlorobi	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
YHH1_k127_6895539_1	1125863.JAFN01000001_gene328	1.194e-13	75.0	COG3897@1|root,COG3897@2|Bacteria,1MUWA@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_16,PrmA
YHH1_k127_6896066_0	880073.Calab_1182	1.48e-195	624.0	COG1748@1|root,COG1748@2|Bacteria,2NNZ1@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lys2	-	1.5.1.10	ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R02315	RC00215,RC00225	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
YHH1_k127_6905650_1	945713.IALB_2428	4.354e-76	265.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
YHH1_k127_6905650_0	1168034.FH5T_01610	1.252e-92	312.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMPG@200643|Bacteroidia	976|Bacteroidetes	T	acetoacetate metabolism regulatory protein AtoC K07714	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_6918777_1	56107.Cylst_4896	1.071e-89	306.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1G0NF@1117|Cyanobacteria,1HJS2@1161|Nostocales	1117|Cyanobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
YHH1_k127_6918777_2	379066.GAU_0688	1.928e-18	98.0	COG4632@1|root,COG4632@2|Bacteria,1ZU1E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
YHH1_k127_6918777_0	945713.IALB_2134	6.903e-167	533.0	COG1154@1|root,COG1154@2|Bacteria	2|Bacteria	H	1-deoxy-D-xylulose-5-phosphate synthase activity	dxs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527	DXP_synthase_N,Transket_pyr,Transketolase_C
YHH1_k127_6920090_0	402777.KB235903_gene784	4.295e-292	910.0	COG2183@1|root,COG2183@2|Bacteria,1G12X@1117|Cyanobacteria,1H7FA@1150|Oscillatoriales	1117|Cyanobacteria	K	Transcriptional accessory protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
YHH1_k127_6922357_1	880073.Calab_2072	7.283e-86	298.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH1_k127_6922357_0	1191523.MROS_0285	1.481e-171	562.0	2E09V@1|root,32VXB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6922813_0	945713.IALB_2996	4.282e-53	196.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	sdh	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH1_k127_6922813_1	665571.STHERM_c21340	1.089e-39	156.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	CP_0776	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	DUF2608,HAD_2
YHH1_k127_6922813_2	1168034.FH5T_11325	1.413e-31	125.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,2FX64@200643|Bacteroidia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH1_k127_692860_0	1313421.JHBV01000039_gene2637	2.672e-115	415.0	COG2831@1|root,COG3291@1|root,COG2831@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
YHH1_k127_692860_1	338966.Ppro_0396	2.292e-48	196.0	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,1N20X@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
YHH1_k127_692860_2	1033737.CAEV01000062_gene3061	0.0006373	44.0	COG0500@1|root,COG2226@2|Bacteria,1TT7G@1239|Firmicutes,24E44@186801|Clostridia,36HEV@31979|Clostridiaceae	186801|Clostridia	Q	NOG31153 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6941289_2	1283300.ATXB01000001_gene2482	4.659e-38	153.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XDX4@135618|Methylococcales	1236|Gammaproteobacteria	T	Nitrogen regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_6941289_1	104623.Ser39006_00715	4.778e-53	201.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSI4@1236|Gammaproteobacteria,402RP@613|Serratia	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
YHH1_k127_6941289_0	1191523.MROS_1845	4.035e-76	263.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria	2|Bacteria	L	metal-sulfur cluster biosynthetic enzyme	mrp	GO:0008150,GO:0040007	-	ko:K02612,ko:K03593,ko:K04488	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
YHH1_k127_6979657_0	1313304.CALK_2436	2.801e-134	442.0	COG3328@1|root,COG3328@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
YHH1_k127_6979657_1	1047013.AQSP01000110_gene67	2.74e-91	303.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YHH1_k127_6991985_0	1303518.CCALI_01306	8.939e-30	132.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Gln_amidase,HYR,RHS_repeat
YHH1_k127_7001309_0	485917.Phep_2066	1.327e-69	252.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
YHH1_k127_7002293_0	945713.IALB_2577	5.692e-128	431.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,HYR,LTD,P_proprotein
YHH1_k127_7002293_2	1121403.AUCV01000007_gene1246	4.266e-09	64.0	COG0484@1|root,COG0484@2|Bacteria,1QWQ7@1224|Proteobacteria,43BV3@68525|delta/epsilon subdivisions,2X762@28221|Deltaproteobacteria,2MPKT@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Tellurite resistance protein TerB	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
YHH1_k127_7002293_1	1410668.JNKC01000001_gene1449	6.594e-40	158.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,36DGZ@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
YHH1_k127_7022218_0	945713.IALB_0752	5.129e-104	345.0	COG0587@1|root,COG0587@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
YHH1_k127_7022218_1	330214.NIDE2626	2.545e-26	112.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
YHH1_k127_7022218_2	118173.KB235914_gene2725	5.592e-23	102.0	COG4679@1|root,COG4679@2|Bacteria,1G6N5@1117|Cyanobacteria,1HC3R@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
YHH1_k127_7022218_3	1125699.HMPREF9194_01866	1.081e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,2J780@203691|Spirochaetes	203691|Spirochaetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
YHH1_k127_7032131_1	1379698.RBG1_1C00001G1104	8.202e-07	59.0	2B0A3@1|root,31SM2@2|Bacteria,2NRWJ@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YHH1_k127_7032131_0	1191523.MROS_2500	5.351e-33	138.0	COG2815@1|root,COG2815@2|Bacteria	2|Bacteria	G	serine threonine protein kinase	spk1	-	2.7.11.1,3.4.16.4,6.3.2.4	ko:K01921,ko:K03587,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01501,ko01502,map00473,map00550,map01100,map01501,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011,ko03036	-	-	-	PASTA,TIR_2
YHH1_k127_7040807_1	1122611.KB903996_gene7554	7.759e-50	187.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria,4EFFN@85012|Streptosporangiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
YHH1_k127_7040807_0	323259.Mhun_1946	1.043e-125	420.0	COG1055@1|root,arCOG00238@2157|Archaea,2XTRK@28890|Euryarchaeota	28890|Euryarchaeota	P	Anion transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
YHH1_k127_7040807_3	519989.ECTPHS_03552	1.422e-30	128.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,1T20E@1236|Gammaproteobacteria,1X2SH@135613|Chromatiales	135613|Chromatiales	G	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
YHH1_k127_7040807_2	768671.ThimaDRAFT_1668	3.318e-47	176.0	COG0758@1|root,COG0758@2|Bacteria,1MZGB@1224|Proteobacteria,1S95S@1236|Gammaproteobacteria,1WYBS@135613|Chromatiales	135613|Chromatiales	LU	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
YHH1_k127_7041576_0	1430331.EP10_08915	1.474e-05	53.0	2A78N@1|root,30W54@2|Bacteria,1TUCC@1239|Firmicutes,4IFFU@91061|Bacilli,1WHAN@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7043929_1	1114959.SZMC14600_06597	1.597e-26	113.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4DXY0@85010|Pseudonocardiales	201174|Actinobacteria	J	PFAM SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
YHH1_k127_7043929_0	1232437.KL661972_gene4775	5.998e-31	133.0	COG0500@1|root,COG2226@2|Bacteria,1NNI3@1224|Proteobacteria,4321D@68525|delta/epsilon subdivisions,2WX0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH1_k127_7044394_1	945713.IALB_2718	5.87e-65	224.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YHH1_k127_7044394_3	1191523.MROS_2507	4.486e-34	142.0	28PR3@1|root,2ZCD0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7044394_0	1341151.ASZU01000003_gene2484	1.304e-108	368.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,27BDZ@186824|Thermoactinomycetaceae	91061|Bacilli	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
YHH1_k127_7044394_2	945713.IALB_2324	6.187e-37	151.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,TPMT
YHH1_k127_7073725_0	945713.IALB_2620	2.819e-205	666.0	COG1198@1|root,COG1198@2|Bacteria	2|Bacteria	L	DNA replication, synthesis of RNA primer	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
YHH1_k127_7073725_1	1191523.MROS_0678	3.182e-17	89.0	2C97T@1|root,338QQ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
YHH1_k127_7073725_2	509191.AEDB02000022_gene2925	9.194e-07	55.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,3WIT1@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,Peptidase_S8,SLH
YHH1_k127_708067_1	797210.Halxa_0191	9.983e-36	145.0	COG3358@1|root,arCOG04570@2157|Archaea,2XX3J@28890|Euryarchaeota,23VM5@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
YHH1_k127_708067_0	945713.IALB_2930	1.986e-105	351.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7114560_9	517418.Ctha_1089	1.279e-10	63.0	COG0088@1|root,COG0088@2|Bacteria,1FDWS@1090|Chlorobi	1090|Chlorobi	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YHH1_k127_7114560_7	1191523.MROS_0214	3.707e-27	113.0	COG0089@1|root,COG0089@2|Bacteria	2|Bacteria	J	rRNA binding	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
YHH1_k127_7114560_0	1191523.MROS_0213	1.052e-126	410.0	COG0090@1|root,COG0090@2|Bacteria	2|Bacteria	J	rRNA binding	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YHH1_k127_7114560_4	1191523.MROS_0212	1.83e-39	148.0	COG0185@1|root,COG0185@2|Bacteria	2|Bacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
YHH1_k127_7114560_5	945713.IALB_0917	6.675e-36	139.0	COG0091@1|root,COG0091@2|Bacteria	2|Bacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
YHH1_k127_7114560_1	1191523.MROS_0210	2.566e-101	333.0	COG0092@1|root,COG0092@2|Bacteria	2|Bacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YHH1_k127_7114560_2	945713.IALB_0919	6.254e-71	241.0	COG0197@1|root,COG0197@2|Bacteria	2|Bacteria	J	tRNA binding	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
YHH1_k127_7114560_10	1501230.ET33_23635	2.838e-08	57.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,26ZBS@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
YHH1_k127_7114560_6	762903.Pedsa_2139	2.003e-29	121.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1IT9T@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
YHH1_k127_7114560_3	1191523.MROS_0206	4.526e-62	214.0	COG0093@1|root,COG0093@2|Bacteria	2|Bacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
YHH1_k127_7114560_8	331678.Cphamn1_2285	1.409e-11	65.0	COG0198@1|root,COG0198@2|Bacteria,1FE6G@1090|Chlorobi	1090|Chlorobi	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
YHH1_k127_7134405_1	743719.PaelaDRAFT_0021	3.844e-06	56.0	COG1988@1|root,COG1988@2|Bacteria,1VKVY@1239|Firmicutes,4HRVT@91061|Bacilli,26UX5@186822|Paenibacillaceae	91061|Bacilli	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
YHH1_k127_7134405_0	1274374.CBLK010000053_gene2491	1.94e-258	808.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,26QCH@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
YHH1_k127_7159805_2	290512.Paes_1652	1.6e-10	64.0	COG0322@1|root,COG0322@2|Bacteria,1FDB2@1090|Chlorobi	1090|Chlorobi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
YHH1_k127_7159805_1	1121931.AUHG01000010_gene328	3.411e-41	155.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,1I1YS@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
YHH1_k127_7159805_3	671143.DAMO_0499	0.0003469	52.0	COG1729@1|root,COG1729@2|Bacteria,2NQ0B@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
YHH1_k127_7159805_0	1191523.MROS_1041	0.0	1224.0	COG0188@1|root,COG0188@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH1_k127_7160673_0	945713.IALB_1751	7.844e-103	362.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	CP_0155	-	-	ko:K08307,ko:K12204	-	-	-	-	ko00000,ko01000,ko01011,ko02044	3.A.7.10.1,3.A.7.9.1	-	-	LysM,SLT,T4SS_TraI
YHH1_k127_7160817_2	406124.ACPC01000019_gene2731	1.187e-05	54.0	COG1664@1|root,COG1664@2|Bacteria,1UIJB@1239|Firmicutes,4ITGM@91061|Bacilli,1ZSBW@1386|Bacillus	91061|Bacilli	M	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
YHH1_k127_7160817_0	1089547.KB913013_gene2908	3.185e-202	655.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,47KYC@768503|Cytophagia	976|Bacteroidetes	M	penicillin-binding protein 1C	-	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
YHH1_k127_7160817_1	700598.Niako_5060	2.306e-144	481.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,1INMI@117747|Sphingobacteriia	976|Bacteroidetes	S	alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
YHH1_k127_7181664_0	1296416.JACB01000029_gene4196	2.621e-101	339.0	COG3422@1|root,COG3422@2|Bacteria,4NHE4@976|Bacteroidetes,1I0UZ@117743|Flavobacteriia,2YHEU@290174|Aquimarina	976|Bacteroidetes	S	double-strand break repair	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7181664_1	1296416.JACB01000029_gene4195	8.336e-99	333.0	COG3291@1|root,COG3291@2|Bacteria,4NI5F@976|Bacteroidetes,1I8AC@117743|Flavobacteriia,2YK1N@290174|Aquimarina	976|Bacteroidetes	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,PKD
YHH1_k127_7186763_0	929556.Solca_3116	1.167e-111	383.0	COG1835@1|root,COG1835@2|Bacteria,4NMNZ@976|Bacteroidetes,1IQXU@117747|Sphingobacteriia	976|Bacteroidetes	I	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
YHH1_k127_7215278_2	1191523.MROS_0346	5.094e-28	115.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
YHH1_k127_7215278_1	1519464.HY22_00860	1.879e-31	126.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YHH1_k127_7215278_0	1051632.TPY_0847	1.007e-124	406.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3WCFP@538999|Clostridiales incertae sedis	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH1_k127_7226403_0	945713.IALB_2978	5.009e-106	348.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YHH1_k127_7226403_2	203275.BFO_0094	8.801e-08	64.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_28,HTH_29,Mu-transpos_C,rve,rve_3
YHH1_k127_7226403_1	1519464.HY22_01110	1.071e-73	256.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
YHH1_k127_7239090_0	945713.IALB_1703	1.187e-34	151.0	COG0457@1|root,COG0457@2|Bacteria	945713.IALB_1703|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7251836_1	56110.Oscil6304_2815	5.091e-14	84.0	COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP
YHH1_k127_7251836_0	555088.DealDRAFT_0819	1.092e-39	158.0	COG2273@1|root,COG5337@1|root,COG2273@2|Bacteria,COG5337@2|Bacteria,1TRAW@1239|Firmicutes,24AQY@186801|Clostridia	186801|Clostridia	M	PFAM Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Dockerin_1,Fn3_assoc,LTD
YHH1_k127_7279399_1	1191523.MROS_0252	1.721e-71	255.0	COG0795@1|root,COG0795@2|Bacteria	2|Bacteria	M	lipopolysaccharide-transporting ATPase activity	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
YHH1_k127_7279399_0	945713.IALB_1918	1.468e-96	341.0	COG4797@1|root,COG4797@2|Bacteria	2|Bacteria	-	-	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
YHH1_k127_7291191_1	517417.Cpar_0777	7.195e-63	228.0	COG1562@1|root,COG1562@2|Bacteria,1FD9U@1090|Chlorobi	1090|Chlorobi	I	PFAM Squalene phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
YHH1_k127_7291191_4	273057.SSO2904	2.753e-08	62.0	arCOG05416@1|root,arCOG05416@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7291191_3	1239962.C943_03491	6.421e-15	78.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia	976|Bacteroidetes	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7291191_2	1191523.MROS_0701	3.872e-22	97.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
YHH1_k127_7291191_0	1191523.MROS_1668	4.066e-83	284.0	2C2F5@1|root,32WND@2|Bacteria	2|Bacteria	-	-	VPA0561	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7312739_1	1379698.RBG1_1C00001G0991	8.738e-22	109.0	COG2911@1|root,COG2931@1|root,COG4447@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4447@2|Bacteria,2NR5X@2323|unclassified Bacteria	2|Bacteria	Q	FlgD Ig-like domain	-	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_3,DUF1735,Laminin_G_3
YHH1_k127_7312739_3	665571.STHERM_c21820	0.0003623	51.0	COG5341@1|root,COG5341@2|Bacteria,2J8UX@203691|Spirochaetes	203691|Spirochaetes	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
YHH1_k127_7312739_0	502025.Hoch_4422	9.768e-93	310.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,43B5T@68525|delta/epsilon subdivisions,2X6JE@28221|Deltaproteobacteria,2Z3BD@29|Myxococcales	28221|Deltaproteobacteria	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
YHH1_k127_7312739_2	469383.Cwoe_5660	3.25e-08	59.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
YHH1_k127_7317099_2	1122176.KB903540_gene20	2.886e-08	65.0	COG0526@1|root,COG1404@1|root,COG0526@2|Bacteria,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	AhpC-TSA,B_lectin,Omp28
YHH1_k127_7317099_0	1379698.RBG1_1C00001G0202	3.248e-117	385.0	COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YHH1_k127_7317099_3	861299.J421_3549	0.0004013	49.0	COG1729@1|root,COG1729@2|Bacteria,1ZTU4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
YHH1_k127_7317099_1	1123487.KB892863_gene1907	3.285e-26	112.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,2VHQA@28216|Betaproteobacteria,2KU9Q@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH1_k127_7353158_0	696369.KI912183_gene2354	5.861e-85	288.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
YHH1_k127_7353158_2	1123248.KB893320_gene3890	2.628e-13	81.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1ITBV@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
YHH1_k127_7353158_1	880073.Calab_1325	4.105e-77	267.0	COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
YHH1_k127_7356163_0	1296416.JACB01000029_gene4195	2.613e-158	536.0	COG3291@1|root,COG3291@2|Bacteria,4NI5F@976|Bacteroidetes,1I8AC@117743|Flavobacteriia,2YK1N@290174|Aquimarina	976|Bacteroidetes	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,PKD
YHH1_k127_7404639_0	525897.Dbac_2100	7.176e-101	334.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2WPVX@28221|Deltaproteobacteria,2MB1S@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
YHH1_k127_7404639_2	269798.CHU_2149	2.592e-14	87.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Cellulase,F5_F8_type_C
YHH1_k127_7404639_1	1237149.C900_03133	1.229e-55	220.0	COG2353@1|root,COG2353@2|Bacteria,4NUV8@976|Bacteroidetes,47UW8@768503|Cytophagia	1237149.C900_03133|-	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7406045_0	1519464.HY22_01110	1.78e-83	287.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
YHH1_k127_7406045_1	1227739.Hsw_0986	9.45e-09	62.0	COG2831@1|root,COG2931@1|root,COG2831@2|Bacteria,COG2931@2|Bacteria,4PPJE@976|Bacteroidetes,47YRQ@768503|Cytophagia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH1_k127_7430059_2	1227349.C170_03603	3.616e-05	50.0	COG5297@1|root,COG5297@2|Bacteria,1V1T2@1239|Firmicutes,4HUDU@91061|Bacilli,26S1Z@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase family 6	guxA	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_3,Glyco_hydro_6,fn3
YHH1_k127_7430059_1	1379698.RBG1_1C00001G0183	3.565e-12	81.0	COG4447@1|root,COG4447@2|Bacteria,2NRC1@2323|unclassified Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_7430059_0	1324957.K933_07127	3.695e-31	144.0	COG1520@1|root,COG3291@1|root,arCOG02482@2157|Archaea,arCOG03504@2157|Archaea,2Y0KJ@28890|Euryarchaeota,23YAH@183963|Halobacteria	183963|Halobacteria	S	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7438533_0	1122137.AQXF01000001_gene3014	9.691e-149	483.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2TRVS@28211|Alphaproteobacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,CBM_48
YHH1_k127_7438533_2	886293.Sinac_2531	5.123e-26	118.0	COG0589@1|root,COG0589@2|Bacteria,2J11D@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YHH1_k127_7438533_1	309807.SRU_1073	2.458e-31	134.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1FJEW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	ComF family	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
YHH1_k127_7441893_1	941449.dsx2_1393	1.047e-24	107.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2M832@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH1_k127_7441893_0	880073.Calab_0711	1.757e-242	763.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH1_k127_7447479_1	404380.Gbem_3581	3.213e-53	207.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42UDC@68525|delta/epsilon subdivisions,2X5AW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
YHH1_k127_7447479_0	1191523.MROS_1723	2.469e-274	861.0	COG1185@1|root,COG1185@2|Bacteria	2|Bacteria	J	polyribonucleotide nucleotidyltransferase activity	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YHH1_k127_7447479_2	945713.IALB_0643	1.561e-30	123.0	COG0184@1|root,COG0184@2|Bacteria	2|Bacteria	J	rRNA binding	rpsO	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
YHH1_k127_7447646_0	1296416.JACB01000029_gene4200	7.241e-175	561.0	COG3501@1|root,COG3501@2|Bacteria,4NFPB@976|Bacteroidetes,1HZN7@117743|Flavobacteriia,2YM49@290174|Aquimarina	976|Bacteroidetes	S	Rhs element Vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
YHH1_k127_7447646_1	1296416.JACB01000029_gene4201	4.594e-105	350.0	COG1652@1|root,COG1652@2|Bacteria,4NJV3@976|Bacteroidetes,1I1VG@117743|Flavobacteriia,2YJMH@290174|Aquimarina	976|Bacteroidetes	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7447646_2	925409.KI911562_gene2391	5.206e-47	170.0	2DMQT@1|root,32T2H@2|Bacteria,4NN19@976|Bacteroidetes,1ISWP@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
YHH1_k127_7458834_0	649638.Trad_0237	1.822e-149	483.0	COG0855@1|root,COG0855@2|Bacteria,1WISM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
YHH1_k127_7458834_2	945713.IALB_1053	2.415e-68	244.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	glcK	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07790	ROK
YHH1_k127_7458834_3	1121104.AQXH01000006_gene2275	5.329e-05	50.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	divIC	-	-	ko:K05589,ko:K12065,ko:K13052	-	-	-	-	ko00000,ko02044,ko03036	3.A.7.11.1	-	-	DivIC
YHH1_k127_7458834_1	234267.Acid_7115	1.39e-113	374.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,3Y3YD@57723|Acidobacteria	57723|Acidobacteria	E	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
YHH1_k127_7466277_1	388413.ALPR1_02680	2.65e-10	70.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,47U6K@768503|Cytophagia	976|Bacteroidetes	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_7466277_0	945713.IALB_1464	4.195e-59	214.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	luxD	-	3.2.1.4,4.2.99.18	ko:K01179,ko:K06889,ko:K10773,ko:K15853	ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko03400	-	GH5,GH9	-	Abhydrolase_1,Acyl_transf_2,DLH,Hydrolase_4,Peptidase_S9
YHH1_k127_7474224_0	1313421.JHBV01000003_gene631	3.236e-22	112.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
YHH1_k127_7476643_0	330214.NIDE0829	1.551e-43	173.0	COG5459@1|root,COG5459@2|Bacteria,3J16W@40117|Nitrospirae	40117|Nitrospirae	J	Mitochondrial small ribosomal subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
YHH1_k127_7476643_1	1392490.JHZX01000001_gene2660	0.0006314	45.0	COG3137@1|root,COG3137@2|Bacteria,4NJH6@976|Bacteroidetes	976|Bacteroidetes	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
YHH1_k127_7480970_0	1191523.MROS_2396	1.236e-72	263.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7494301_1	485913.Krac_12573	1.579e-23	103.0	COG0249@1|root,COG0249@2|Bacteria,2G8CJ@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA mismatch repair protein MutS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
YHH1_k127_7494301_0	37659.JNLN01000001_gene1277	1.238e-36	153.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,36DC9@31979|Clostridiaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
YHH1_k127_7511079_0	945713.IALB_2731	9.081e-153	501.0	COG1523@1|root,COG1523@2|Bacteria	2|Bacteria	G	belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.41,3.2.1.68	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,PUD
YHH1_k127_7518590_0	1191523.MROS_1942	8.641e-50	186.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	fadR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
YHH1_k127_7518590_2	1158294.JOMI01000003_gene2726	3.071e-14	78.0	COG1670@1|root,COG1670@2|Bacteria,4NR3B@976|Bacteroidetes,2FVYG@200643|Bacteroidia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YHH1_k127_7518590_1	330214.NIDE3490	1.23e-18	94.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Phasin_2
YHH1_k127_753363_1	338966.Ppro_0396	3.4e-69	259.0	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,1N20X@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
YHH1_k127_753363_0	945713.IALB_1252	6.96e-79	276.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
YHH1_k127_753363_3	1380390.JIAT01000015_gene5725	7.203e-30	127.0	COG0726@1|root,COG0726@2|Bacteria,2GMC2@201174|Actinobacteria,4CQU1@84995|Rubrobacteria	84995|Rubrobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
YHH1_k127_753363_2	1191523.MROS_2067	5.04e-34	136.0	28PUG@1|root,2ZCFG@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
YHH1_k127_757929_0	1121930.AQXG01000007_gene490	6.221e-78	295.0	COG1649@1|root,COG4254@1|root,COG4733@1|root,COG1649@2|Bacteria,COG4254@2|Bacteria,COG4733@2|Bacteria,4NT4E@976|Bacteroidetes,1IU8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7581237_0	1463841.JOIR01000009_gene4048	1.154e-220	701.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase E1 component	kgd	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
YHH1_k127_7587118_2	880073.Calab_1047	1.381e-22	99.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	pagC	-	-	ko:K07804	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ail_Lom,OMP_b-brl
YHH1_k127_7587118_1	1191523.MROS_0657	4.331e-55	200.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHU_C,Cu_amine_oxidN1,FlgD_ig
YHH1_k127_7587118_0	886379.AEWI01000020_gene1348	1.51e-200	645.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,2FN1K@200643|Bacteroidia,3XJPB@558415|Marinilabiliaceae	976|Bacteroidetes	EU	Prolyl oligopeptidase family	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YHH1_k127_7595842_0	929703.KE386491_gene1701	2.27e-58	211.0	COG1106@1|root,COG1106@2|Bacteria,4NE5J@976|Bacteroidetes,47NIN@768503|Cytophagia	976|Bacteroidetes	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
YHH1_k127_7595842_1	686340.Metal_3631	6.49e-21	94.0	COG1309@1|root,COG1309@2|Bacteria,1NDME@1224|Proteobacteria,1SAB5@1236|Gammaproteobacteria,1XFPV@135618|Methylococcales	135618|Methylococcales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF1956,TetR_N
YHH1_k127_7606286_0	1121904.ARBP01000030_gene1930	1.719e-146	475.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47K8C@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YHH1_k127_7616995_0	768670.Calni_0847	4.787e-52	203.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,2GG9I@200930|Deferribacteres	200930|Deferribacteres	G	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
YHH1_k127_7621979_0	1191523.MROS_2763	1.235e-125	415.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
YHH1_k127_762601_1	1379698.RBG1_1C00001G1784	1.241e-27	126.0	COG3391@1|root,COG3391@2|Bacteria,2NQ4G@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,DUF5128,NHL
YHH1_k127_762601_0	290512.Paes_1964	6.106e-36	138.0	COG0629@1|root,COG0629@2|Bacteria,1FE0M@1090|Chlorobi	1090|Chlorobi	L	PFAM single-strand binding protein Primosomal replication protein n	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YHH1_k127_7635298_2	926569.ANT_11030	7.368e-10	70.0	COG1449@1|root,COG4945@1|root,COG1449@2|Bacteria,COG4945@2|Bacteria	2|Bacteria	G	C-terminal binding-module, SLH-like, of glucodextranase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Glucodextran_C,Glyco_hydro_57
YHH1_k127_7635298_1	941824.TCEL_00374	5.851e-14	80.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,36EH5@31979|Clostridiaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
YHH1_k127_7635298_0	1453500.AT05_01565	3.298e-50	184.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1I1XN@117743|Flavobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
YHH1_k127_7642636_1	1114959.SZMC14600_12595	2.343e-06	51.0	COG0745@1|root,COG0745@2|Bacteria,2GJRR@201174|Actinobacteria,4E212@85010|Pseudonocardiales	201174|Actinobacteria	KT	Forms part of a two-component regulatory system AfsQ1 AfsQ2 involved in secondary metabolism	afsQ1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_7642636_0	1519464.HY22_09075	7.323e-90	325.0	COG0642@1|root,COG2205@2|Bacteria	1519464.HY22_09075|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7651319_0	1191523.MROS_1459	6.558e-107	354.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	dnaJ	GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH1_k127_7651319_2	1120933.ATUY01000004_gene975	7.349e-17	86.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4D3V2@85005|Actinomycetales	201174|Actinobacteria	L	ComEA protein	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
YHH1_k127_7651319_1	1504319.GM45_4345	1.425e-25	109.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,3UWU4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
YHH1_k127_7656112_0	1313421.JHBV01000015_gene5729	1.661e-44	187.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Gram_pos_anchor
YHH1_k127_7656112_1	1239962.C943_01339	1.574e-30	141.0	COG3866@1|root,COG4254@1|root,COG5492@1|root,COG3866@2|Bacteria,COG4254@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	pel3	-	-	-	-	-	-	-	-	-	-	-	FecR,Pectinesterase
YHH1_k127_7661511_1	160799.PBOR_03860	9.615e-10	68.0	COG3857@1|root,COG3857@2|Bacteria,1TS95@1239|Firmicutes,4HUWE@91061|Bacilli,26UMT@186822|Paenibacillaceae	91061|Bacilli	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
YHH1_k127_7661511_0	309807.SRU_1806	3.622e-63	231.0	COG1074@1|root,COG1074@2|Bacteria,4PF12@976|Bacteroidetes,1FJZ4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH1_k127_7667431_6	520999.PROVALCAL_01880	0.0003277	47.0	2E35X@1|root,32Y5T@2|Bacteria,1N787@1224|Proteobacteria,1SDVX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7667431_0	118173.KB235914_gene1474	2.388e-60	233.0	COG2911@1|root,COG2931@1|root,COG3391@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1G2NP@1117|Cyanobacteria,1H73B@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,HemolysinCabind
YHH1_k127_7667431_5	1519464.HY22_04545	2.564e-16	93.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSII_BNR,fn3
YHH1_k127_7667431_2	1396141.BATP01000021_gene179	5.353e-48	194.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,PQQ_2
YHH1_k127_7667431_3	1267535.KB906767_gene1958	1.446e-40	173.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480,ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
YHH1_k127_7667431_1	1267535.KB906767_gene1959	2.783e-49	184.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_7667431_4	1267535.KB906767_gene1960	1.723e-16	84.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg,TauD
YHH1_k127_7669202_2	1131269.AQVV01000010_gene2453	7.266e-07	57.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
YHH1_k127_7669202_0	159087.Daro_0688	1.761e-170	543.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2VIPV@28216|Betaproteobacteria,2KZEB@206389|Rhodocyclales	206389|Rhodocyclales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	-	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
YHH1_k127_7669202_1	351160.RCIX2198	1.052e-10	73.0	COG4354@1|root,arCOG03865@2157|Archaea	2157|Archaea	G	intracellular protein transport	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YHH1_k127_7671254_2	903818.KI912268_gene1340	3.331e-36	145.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
YHH1_k127_7671254_1	290512.Paes_2157	1.749e-58	218.0	COG0778@1|root,COG0778@2|Bacteria,1FEYA@1090|Chlorobi	1090|Chlorobi	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7671254_0	700598.Niako_5053	3.067e-89	312.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_7678886_0	1267535.KB906767_gene1958	3.281e-35	155.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480,ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
YHH1_k127_7678886_1	518766.Rmar_2211	1.407e-06	53.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729,ko:K12287	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000,ko02044	-	-	-	Alginate_lyase2,Beta_helix,Big_2,DUF11,F5_F8_type_C,LTD,Laminin_G_3
YHH1_k127_769559_0	1121439.dsat_0706	2.314e-82	287.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria,2M8HM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,PAS_8
YHH1_k127_769559_2	1122176.KB903537_gene1641	1.687e-24	121.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Omp28,Reprolysin_5,SLH
YHH1_k127_769786_1	649349.Lbys_2685	5.359e-08	57.0	2CFGC@1|root,33FFI@2|Bacteria,4NZ32@976|Bacteroidetes,47WF6@768503|Cytophagia	976|Bacteroidetes	S	sptr putative	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_769786_0	234267.Acid_2630	1.48e-150	493.0	COG3666@1|root,COG3666@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
YHH1_k127_769786_2	1032480.MLP_07040	1.945e-06	55.0	COG1653@1|root,COG1653@2|Bacteria,2HT29@201174|Actinobacteria	201174|Actinobacteria	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
YHH1_k127_7701413_2	1519464.HY22_13435	1.213e-23	103.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	hybA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
YHH1_k127_7701413_0	1519464.HY22_13440	1.755e-91	304.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,GSu_C4xC__C2xCH,UVR
YHH1_k127_7701413_1	1033802.SSPSH_000617	8.536e-29	119.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH1_k127_7709268_1	1121904.ARBP01000011_gene1450	7.124e-135	435.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,47NGE@768503|Cytophagia	976|Bacteroidetes	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
YHH1_k127_7709268_0	1519464.HY22_04890	1.799e-189	617.0	COG1629@1|root,COG4771@2|Bacteria,1FEFM@1090|Chlorobi	1090|Chlorobi	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH1_k127_7710885_1	1121035.AUCH01000013_gene3156	1.274e-53	196.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,2KUC0@206389|Rhodocyclales	206389|Rhodocyclales	I	phytoene	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
YHH1_k127_7710885_0	1191523.MROS_2828	3.298e-78	270.0	COG1562@1|root,COG1562@2|Bacteria	2|Bacteria	I	ergosterol biosynthetic process	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
YHH1_k127_7710885_2	945713.IALB_1922	7.889e-45	179.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
YHH1_k127_7726830_0	1519464.HY22_12340	1.578e-179	582.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1FEI3@1090|Chlorobi	1090|Chlorobi	GJM	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
YHH1_k127_7726830_2	1191523.MROS_0370	6.708e-48	176.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
YHH1_k127_7726830_1	742743.HMPREF9453_00746	2.706e-126	417.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4H20Q@909932|Negativicutes	909932|Negativicutes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YHH1_k127_7731792_6	1267534.KB906758_gene2161	3.901e-05	51.0	COG1193@1|root,COG1193@2|Bacteria,3Y2Z2@57723|Acidobacteria,2JHU4@204432|Acidobacteriia	204432|Acidobacteriia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
YHH1_k127_7731792_3	1128427.KB904821_gene1896	2.859e-39	152.0	COG1610@1|root,COG1610@2|Bacteria,1G607@1117|Cyanobacteria,1HB1I@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
YHH1_k127_7731792_1	1191523.MROS_2569	4.201e-48	178.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH1_k127_7731792_4	1191523.MROS_2570	1.236e-38	150.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH1_k127_7731792_0	1191523.MROS_2571	1.832e-83	284.0	COG0811@1|root,COG0811@2|Bacteria	2|Bacteria	U	bacteriocin transport	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH1_k127_7731792_2	1120972.AUMH01000018_gene1944	6.556e-46	174.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,4HBPF@91061|Bacilli	91061|Bacilli	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	-	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
YHH1_k127_7734684_0	649349.Lbys_2001	6.536e-54	202.0	COG3188@1|root,COG3188@2|Bacteria,4NHCJ@976|Bacteroidetes,47K9Y@768503|Cytophagia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7734684_1	1121098.HMPREF1534_01643	8.061e-28	129.0	COG0514@1|root,COG0514@2|Bacteria,4NIG1@976|Bacteroidetes,2FPYY@200643|Bacteroidia,4ASXM@815|Bacteroidaceae	976|Bacteroidetes	L	helicase superfamily c-terminal domain	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
YHH1_k127_7735299_1	598659.NAMH_1287	1.112e-10	64.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2YM8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
YHH1_k127_7735299_0	207559.Dde_3784	1.546e-77	277.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH1_k127_7760712_0	945713.IALB_2863	5.406e-38	163.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	CARDB,FTP,He_PIG,PA,Peptidase_M30,Peptidase_M36,Peptidase_M6
YHH1_k127_7765739_0	360910.BAV1503	7.814e-31	129.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2VHTZ@28216|Betaproteobacteria,3T338@506|Alcaligenaceae	28216|Betaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
YHH1_k127_776683_0	1047013.AQSP01000128_gene441	1.252e-61	228.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	-	-	-	ko:K11744	-	-	-	-	ko00000	-	-	-	AI-2E_transport
YHH1_k127_776683_1	945713.IALB_0011	4.663e-45	168.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YHH1_k127_776683_2	518766.Rmar_2511	4.433e-42	164.0	COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1FIS6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	DnaJ molecular chaperone homology domain	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
YHH1_k127_776683_3	1210884.HG799465_gene12283	4.955e-05	49.0	COG0542@1|root,COG0542@2|Bacteria,2IWYZ@203682|Planctomycetes	203682|Planctomycetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH1_k127_779520_2	929556.Solca_2863	3.582e-21	94.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,4NFYC@976|Bacteroidetes,1IPQ6@117747|Sphingobacteriia	976|Bacteroidetes	FL	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
YHH1_k127_779520_0	378806.STAUR_6820	8.143e-72	248.0	2CDDP@1|root,33XZD@2|Bacteria,1NVRR@1224|Proteobacteria,4380H@68525|delta/epsilon subdivisions,2X3AJ@28221|Deltaproteobacteria,2YV52@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7803881_0	671143.DAMO_1696	2.832e-39	162.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
YHH1_k127_7803881_1	1150474.JQJI01000050_gene1086	1.78e-15	78.0	COG0004@1|root,COG0004@2|Bacteria,2GD3C@200918|Thermotogae	200918|Thermotogae	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
YHH1_k127_7807882_1	1120973.AQXL01000133_gene1776	4.543e-128	427.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,4H9ZS@91061|Bacilli,2783C@186823|Alicyclobacillaceae	91061|Bacilli	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH
YHH1_k127_7807882_2	1123054.KB907721_gene2985	1.755e-44	173.0	2CWKB@1|root,32SZW@2|Bacteria,1RD54@1224|Proteobacteria,1S4QG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7807882_0	945713.IALB_0608	2.651e-180	588.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
YHH1_k127_7807882_3	551789.ATVJ01000004_gene408	5.215e-08	58.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria,2UFG4@28211|Alphaproteobacteria,43YX4@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7809879_0	1121920.AUAU01000007_gene439	0.0	1112.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria	2|Bacteria	I	cobalamin binding	icmF	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
YHH1_k127_7810698_4	584708.Apau_0469	2.517e-22	99.0	COG1669@1|root,COG1669@2|Bacteria,3TCHP@508458|Synergistetes	508458|Synergistetes	L	Addiction module antitoxin, RelB DinJ family	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2,RelB
YHH1_k127_7810698_2	246194.CHY_2535	8.536e-29	119.0	COG2361@1|root,COG2361@2|Bacteria,1VFEB@1239|Firmicutes,24QN5@186801|Clostridia,42HA4@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
YHH1_k127_7810698_0	456442.Mboo_2258	4.78e-60	214.0	arCOG03570@1|root,arCOG03570@2157|Archaea	2157|Archaea	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TehB
YHH1_k127_7810698_5	65393.PCC7424_2669	9.529e-16	77.0	COG1724@1|root,COG1724@2|Bacteria,1G7R9@1117|Cyanobacteria,3KIZN@43988|Cyanothece	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH1_k127_7810698_3	1496688.ER33_08565	2.186e-23	100.0	COG1598@1|root,COG1598@2|Bacteria,1G97T@1117|Cyanobacteria,22T49@167375|Cyanobium	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
YHH1_k127_7810698_1	1305737.JAFX01000001_gene547	3.167e-33	130.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,47PIS@768503|Cytophagia	976|Bacteroidetes	M	Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YHH1_k127_7814176_2	1221522.B723_29005	4.414e-42	156.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1YQBS@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hinT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019478,GO:0019752,GO:0043436,GO:0043530,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055130,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
YHH1_k127_7814176_3	945713.IALB_1366	8.243e-35	139.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7814176_5	298386.PBPRA2670	9.536e-33	133.0	COG2445@1|root,COG2445@2|Bacteria,1QYJX@1224|Proteobacteria	1224|Proteobacteria	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
YHH1_k127_7814176_6	1123278.KB893544_gene4851	1.403e-18	89.0	COG1708@1|root,COG1708@2|Bacteria,4NUN4@976|Bacteroidetes,47SHP@768503|Cytophagia	976|Bacteroidetes	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH1_k127_7814176_4	443143.GM18_1427	6.647e-33	134.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2WPT4@28221|Deltaproteobacteria,43UYH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
YHH1_k127_7814176_1	1191523.MROS_0384	1.651e-101	337.0	COG2877@1|root,COG2877@2|Bacteria	2|Bacteria	M	3-deoxy-8-phosphooctulonate synthase activity	kdsA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
YHH1_k127_7814176_0	1191523.MROS_1017	2.993e-139	451.0	COG0216@1|root,COG0216@2|Bacteria	2|Bacteria	J	translation release factor activity	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH1_k127_7820995_0	945713.IALB_2256	2.525e-219	698.0	COG0210@1|root,COG0210@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH1_k127_7825298_0	443143.GM18_4011	5.16e-158	527.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria,43T72@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	ATP-binding region, ATPase domain protein	cheA4	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
YHH1_k127_7825298_1	443143.GM18_4012	0.0009165	42.0	COG0642@1|root,COG0840@1|root,COG0840@2|Bacteria,COG2205@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
YHH1_k127_7834212_0	391625.PPSIR1_08312	3.522e-74	269.0	COG5434@1|root,COG5434@2|Bacteria,1RJPM@1224|Proteobacteria,42T21@68525|delta/epsilon subdivisions,2WPCS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH1_k127_7834212_1	927658.AJUM01000042_gene1629	2.194e-71	248.0	COG1266@1|root,COG1266@2|Bacteria,4NRAH@976|Bacteroidetes,2FS5H@200643|Bacteroidia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
YHH1_k127_7834212_2	1185876.BN8_01934	1.167e-21	96.0	COG2318@1|root,COG2318@2|Bacteria,4NNQA@976|Bacteroidetes,47Q00@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH1_k127_7843608_0	502025.Hoch_6665	7.884e-144	477.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YXKT@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_7843608_1	391625.PPSIR1_22466	1.223e-130	431.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,433Y1@68525|delta/epsilon subdivisions,2X41I@28221|Deltaproteobacteria,2YXYJ@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_7855052_0	1519464.HY22_04900	9.01e-116	393.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,1FEZZ@1090|Chlorobi	1090|Chlorobi	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
YHH1_k127_7861582_0	1191523.MROS_0313	7.941e-81	286.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	-	R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	GT28	iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Glyco_tran_28_C,Glyco_transf_28
YHH1_k127_7861582_1	945713.IALB_2207	1.18e-13	73.0	COG0772@1|root,COG0772@2|Bacteria	2|Bacteria	D	peptidoglycan glycosyltransferase activity	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
YHH1_k127_7866107_2	883.DvMF_0337	3.467e-08	60.0	COG0204@1|root,COG0204@2|Bacteria,1PY44@1224|Proteobacteria,42NR4@68525|delta/epsilon subdivisions,2WKKQ@28221|Deltaproteobacteria,2MAGC@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH1_k127_7866107_0	1191523.MROS_0288	6.077e-180	570.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YHH1_k127_7866107_1	945713.IALB_0753	1.521e-82	282.0	COG1028@1|root,COG1028@2|Bacteria	945713.IALB_0753|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7867969_1	880071.Fleli_3059	1.842e-16	91.0	COG4252@1|root,COG4252@2|Bacteria,4NMM6@976|Bacteroidetes,47PFU@768503|Cytophagia	976|Bacteroidetes	T	CHASE2 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2
YHH1_k127_7867969_0	1191523.MROS_1891	2.995e-88	303.0	COG0729@1|root,COG0823@1|root,COG0729@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	treP	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,PD40
YHH1_k127_7869224_3	1121930.AQXG01000007_gene423	6.032e-23	106.0	COG2911@1|root,COG4677@1|root,COG2911@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	3.2.1.51,4.2.2.23	ko:K10297,ko:K15923,ko:K18197,ko:K20276	ko00511,ko02024,map00511,map02024	-	-	-	ko00000,ko00001,ko01000,ko04121	-	GH95,PL11	-	Beta_helix,CHU_C
YHH1_k127_7869224_0	945713.IALB_0026	4.658e-180	569.0	COG1830@1|root,COG1830@2|Bacteria	2|Bacteria	G	lyase activity	fbaB	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640	DeoC
YHH1_k127_7869224_1	469383.Cwoe_2865	2.963e-89	303.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4CQ48@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
YHH1_k127_7869224_2	204669.Acid345_1412	1.175e-69	240.0	COG2316@1|root,COG2316@2|Bacteria,3Y4GI@57723|Acidobacteria,2JJBG@204432|Acidobacteriia	204432|Acidobacteriia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
YHH1_k127_7943992_1	1122179.KB890422_gene2240	1.517e-27	129.0	COG2931@1|root,COG3227@1|root,COG3292@1|root,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3292@2|Bacteria,4NHTI@976|Bacteroidetes	976|Bacteroidetes	T	zinc metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	CUB,Pep_M12B_propep,Reprolysin_5
YHH1_k127_7943992_0	443144.GM21_3621	1.729e-37	148.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,43V12@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
YHH1_k127_7943992_4	1294265.JCM21738_5280	9.156e-06	58.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZFAP@1386|Bacillus	91061|Bacilli	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	stoA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH1_k127_7943992_3	1121104.AQXH01000005_gene258	1.549e-08	61.0	2A7GB@1|root,30WDY@2|Bacteria,4P9A3@976|Bacteroidetes	976|Bacteroidetes	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
YHH1_k127_7949543_0	204669.Acid345_2944	3.953e-57	208.0	COG0437@1|root,COG0437@2|Bacteria,3Y5RE@57723|Acidobacteria,2JKSV@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	DmsC,Fer4_11
YHH1_k127_7949543_1	1121920.AUAU01000012_gene2646	3.956e-27	119.0	COG0509@1|root,COG2204@1|root,COG0509@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GAF_2,GCV_H,Response_reg
YHH1_k127_7951361_1	945713.IALB_1689	1.872e-111	368.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	JD73_00815	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH1_k127_7951361_0	234267.Acid_5012	9.974e-239	745.0	COG0008@1|root,COG0008@2|Bacteria,3Y7DS@57723|Acidobacteria	57723|Acidobacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	-	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
YHH1_k127_7951469_0	706587.Desti_2677	1.321e-34	153.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	-	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
YHH1_k127_7951469_1	1120934.KB894404_gene746	0.0001012	55.0	COG1520@1|root,COG1680@1|root,COG1520@2|Bacteria,COG1680@2|Bacteria,2HSCZ@201174|Actinobacteria,4EDAG@85010|Pseudonocardiales	201174|Actinobacteria	V	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7965095_1	1382359.JIAL01000001_gene613	6.34e-08	59.0	COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria,3Y3Y6@57723|Acidobacteria,2JI5Y@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
YHH1_k127_7965095_0	382464.ABSI01000010_gene3492	2.421e-58	224.0	2DBYV@1|root,2ZBXC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7992450_1	1297742.A176_01429	4.854e-28	119.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WN3N@28221|Deltaproteobacteria,2YVHP@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
YHH1_k127_7992450_0	1249627.D779_1180	1.032e-50	200.0	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria,1WXGP@135613|Chromatiales	135613|Chromatiales	KT	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K01079,ko:K07315	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03021	-	-	-	GAF,HAMP,SpoIIE,dCache_1
YHH1_k127_7995147_1	880073.Calab_3533	7.156e-08	57.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	PPC
YHH1_k127_7995147_0	945713.IALB_0649	7.98e-181	594.0	COG1674@1|root,COG1674@2|Bacteria	2|Bacteria	D	ftsk spoiiie	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YHH1_k127_8020131_0	945713.IALB_2429	5.119e-77	263.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_8020131_1	234267.Acid_4208	5.827e-39	151.0	COG1913@1|root,COG1913@2|Bacteria,3Y880@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
YHH1_k127_8020131_2	945713.IALB_0884	3.336e-23	114.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_8050875_0	880073.Calab_1428	9.122e-146	474.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	hoxF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K05587,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
YHH1_k127_8050875_1	1191523.MROS_2480	7.237e-55	197.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YHH1_k127_8053285_0	194439.CT2259	1.428e-102	343.0	COG2171@1|root,COG2171@2|Bacteria,1FDRM@1090|Chlorobi	1090|Chlorobi	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
YHH1_k127_8053285_1	203124.Tery_2349	2.76e-32	133.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
YHH1_k127_8054861_2	641143.HMPREF9331_01438	4.912e-07	59.0	2CG1Y@1|root,31EK1@2|Bacteria,4NUTU@976|Bacteroidetes,1IJMJ@117743|Flavobacteriia,1ERTU@1016|Capnocytophaga	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YHH1_k127_8054861_1	945713.IALB_0274	4.407e-72	247.0	COG1014@1|root,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porG	-	1.2.7.3,1.2.7.7	ko:K00177,ko:K00187	ko00020,ko00280,ko00720,ko01100,ko01120,ko01200,map00020,map00280,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197,R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
YHH1_k127_8054861_0	1191523.MROS_2263	1.202e-98	324.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	vorB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00175,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
YHH1_k127_8086568_0	370438.PTH_1208	2.422e-72	258.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,26079@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM peptidase T-like protein	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
YHH1_k127_8086568_1	1123508.JH636446_gene6211	5.649e-70	243.0	COG0177@1|root,COG0177@2|Bacteria,2IYYT@203682|Planctomycetes	203682|Planctomycetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
YHH1_k127_8090102_0	1121930.AQXG01000002_gene2395	1.718e-148	474.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1IQQ4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
YHH1_k127_8090102_1	880073.Calab_0645	6.177e-134	443.0	COG3537@1|root,COG3537@2|Bacteria,2NQQ0@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
YHH1_k127_8093836_1	880073.Calab_3642	3.459e-92	308.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
YHH1_k127_8093836_0	880073.Calab_3643	3.136e-141	463.0	COG2268@1|root,COG2268@2|Bacteria,2NPBZ@2323|unclassified Bacteria	2|Bacteria	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
YHH1_k127_8093836_2	269799.Gmet_0074	2.993e-16	83.0	COG3943@1|root,COG3943@2|Bacteria,1QY8E@1224|Proteobacteria	1224|Proteobacteria	S	COG3943, virulence protein	-	-	-	ko:K14623	-	-	-	-	ko00000,ko03400	-	-	-	-
YHH1_k127_8093836_3	1121930.AQXG01000023_gene1642	3.188e-06	52.0	COG0737@1|root,COG2374@1|root,COG0737@2|Bacteria,COG2374@2|Bacteria,4PPNB@976|Bacteroidetes,1IY1S@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	-	-	-	-	-	-	-	-	-	-	-	-	LTD
YHH1_k127_8113901_1	1035193.HMPREF9073_02116	1.665e-22	99.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1HXV5@117743|Flavobacteriia,1EQE8@1016|Capnocytophaga	976|Bacteroidetes	H	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	1.1.3.48,2.7.7.38	ko:K00979,ko:K19714	ko00540,ko01100,map00540,map01100	M00063	R03351,R11394,R11396	RC00152,RC00910,RC03427	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
YHH1_k127_8113901_0	945713.IALB_0623	1.533e-161	520.0	COG0621@1|root,COG0621@2|Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
YHH1_k127_8119179_2	411489.CLOL250_01586	5.929e-17	94.0	COG2304@1|root,COG2304@2|Bacteria,1TQXZ@1239|Firmicutes	1239|Firmicutes	S	von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
YHH1_k127_8119179_0	313606.M23134_05227	2.443e-140	477.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
YHH1_k127_8119179_1	1229487.AMYW01000083_gene3585	6.843e-38	164.0	COG3391@1|root,COG3391@2|Bacteria,4PMIF@976|Bacteroidetes,1IKM0@117743|Flavobacteriia,2P0WA@237|Flavobacterium	976|Bacteroidetes	N	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR,Laminin_G_3
YHH1_k127_8134661_2	880073.Calab_2496	2.13e-51	185.0	COG0864@1|root,COG0864@2|Bacteria,2NR9B@2323|unclassified Bacteria	2|Bacteria	K	Ribbon-helix-helix protein, copG family	nikR	GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016151,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032991,GO:0032993,GO:0042802,GO:0043167,GO:0043169,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071840,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
YHH1_k127_8134661_5	679935.Alfi_1054	3.333e-06	58.0	COG0619@1|root,COG0619@2|Bacteria	2|Bacteria	P	transmembrane transporter activity	cbiQ	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02007,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
YHH1_k127_8134661_1	383372.Rcas_4263	4.499e-64	229.0	COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi,3764I@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
YHH1_k127_8134661_0	880073.Calab_2499	9.603e-146	482.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH1_k127_8134661_3	880073.Calab_2500	6.887e-32	132.0	298ZI@1|root,30K3I@2|Bacteria,2NRUN@2323|unclassified Bacteria	2|Bacteria	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8134661_4	1111454.HMPREF1250_1295	1.294e-16	85.0	COG0500@1|root,COG1937@1|root,COG1937@2|Bacteria,COG2226@2|Bacteria,1VA7S@1239|Firmicutes,4H54D@909932|Negativicutes	909932|Negativicutes	Q	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Methyltransf_25,Trns_repr_metal
YHH1_k127_8138353_1	1121859.KB890738_gene3530	1.459e-19	103.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_8138353_0	240016.ABIZ01000001_gene5114	3.459e-30	125.0	COG1670@1|root,COG1670@2|Bacteria,46TPM@74201|Verrucomicrobia,2IUXY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YHH1_k127_8167447_0	194439.CT1479	7.364e-130	428.0	COG0773@1|root,COG0773@2|Bacteria,1FDEE@1090|Chlorobi	1090|Chlorobi	M	PFAM cytoplasmic peptidoglycan synthetase domain protein	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_8167447_3	1121936.AUHI01000006_gene1919	5.001e-13	74.0	2E363@1|root,32Y5Y@2|Bacteria,1W3CU@1239|Firmicutes,4HZRV@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8167447_2	1286171.EAL2_808p07490	4.237e-69	243.0	COG3384@1|root,COG3384@2|Bacteria,1TSRZ@1239|Firmicutes,24B3B@186801|Clostridia,25WQU@186806|Eubacteriaceae	186801|Clostridia	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
YHH1_k127_8167447_1	1123371.ATXH01000013_gene1529	1.335e-118	390.0	COG0152@1|root,COG0152@2|Bacteria,2GH07@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
YHH1_k127_8169274_0	1174528.JH992898_gene2614	2.742e-57	218.0	COG4995@1|root,COG4995@2|Bacteria,1GDW4@1117|Cyanobacteria	1117|Cyanobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
YHH1_k127_8186518_2	945713.IALB_2215	4.215e-38	148.0	COG2001@1|root,COG2001@2|Bacteria	2|Bacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
YHH1_k127_8186518_1	646529.Desaci_3765	1.335e-77	270.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,260DT@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
YHH1_k127_8186518_0	517418.Ctha_0827	2.94e-138	460.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1FDDH@1090|Chlorobi	1090|Chlorobi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
YHH1_k127_8211241_0	1191523.MROS_0699	8.698e-22	104.0	2EJ6V@1|root,33CY2@2|Bacteria	2|Bacteria	S	Yip1 domain	yknW	-	-	-	-	-	-	-	-	-	-	-	Yip1
YHH1_k127_8219448_1	502025.Hoch_4734	7.907e-109	358.0	COG1164@1|root,COG1164@2|Bacteria,1Q3C4@1224|Proteobacteria,4393F@68525|delta/epsilon subdivisions,2X49B@28221|Deltaproteobacteria,2YYJ7@29|Myxococcales	28221|Deltaproteobacteria	E	Oligoendopeptidase f	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8219448_0	1379698.RBG1_1C00001G0686	9.866e-124	409.0	COG1252@1|root,COG1252@2|Bacteria,2NP3T@2323|unclassified Bacteria	2|Bacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh	GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iYO844.BSU12290,iYO844.BSU32100	Pyr_redox_2
YHH1_k127_8230032_2	1191523.MROS_2068	4.421e-69	241.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
YHH1_k127_8230032_5	1191523.MROS_1840	1.27e-42	165.0	COG4359@1|root,COG4359@2|Bacteria	2|Bacteria	E	L-methionine salvage from methylthioadenosine	mtnX	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	HAD,Put_Phosphatase
YHH1_k127_8230032_0	1382304.JNIL01000001_gene2814	5.523e-109	370.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,2782N@186823|Alicyclobacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH1_k127_8230032_7	945713.IALB_2098	3.447e-15	76.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
YHH1_k127_8230032_1	518766.Rmar_2306	5.895e-99	330.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1FIWZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
YHH1_k127_8230032_6	290512.Paes_1474	5.28e-24	103.0	COG1828@1|root,COG1828@2|Bacteria,1FE7V@1090|Chlorobi	1090|Chlorobi	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
YHH1_k127_8230032_4	517418.Ctha_0208	1.79e-53	198.0	COG1183@1|root,COG1183@2|Bacteria,1FDS1@1090|Chlorobi	1090|Chlorobi	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
YHH1_k127_8230032_3	945713.IALB_2094	4.251e-63	223.0	COG0688@1|root,COG0688@2|Bacteria	2|Bacteria	I	phosphatidylethanolamine metabolic process	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
YHH1_k127_83304_0	926550.CLDAP_02910	4.282e-130	430.0	COG2270@1|root,COG2270@2|Bacteria,2G633@200795|Chloroflexi	200795|Chloroflexi	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
YHH1_k127_83304_1	518766.Rmar_2201	6.297e-50	194.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1FISC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH1_k127_8341930_0	1191523.MROS_0285	8.56e-73	274.0	2E09V@1|root,32VXB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8361058_0	525146.Ddes_1505	1.161e-137	449.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42Q6J@68525|delta/epsilon subdivisions,2WKXA@28221|Deltaproteobacteria,2M7TR@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Biotin and Thiamin Synthesis associated	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
YHH1_k127_8368409_2	1279009.ADICEAN_03991	3.766e-11	76.0	COG5624@1|root,COG5624@2|Bacteria,4NZQQ@976|Bacteroidetes	976|Bacteroidetes	K	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8368409_3	880073.Calab_0123	6.598e-11	75.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Lectin_legB,NB-ARC,TIR_2,WD40
YHH1_k127_8368409_1	518766.Rmar_2442	2.937e-11	78.0	COG0737@1|root,COG0737@2|Bacteria,4PNDC@976|Bacteroidetes,1FJX0@1100069|Bacteroidetes Order II. Incertae sedis	2|Bacteria	F	pectinesterase activity	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	LRR_5,SBP_bac_8,TAT_signal
YHH1_k127_8368409_4	880070.Cycma_0059	3.079e-06	61.0	COG3866@1|root,COG3866@2|Bacteria,4NQ5V@976|Bacteroidetes	976|Bacteroidetes	G	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Pec_lyase_C
YHH1_k127_8368409_0	755731.Clo1100_3315	1.376e-61	243.0	COG4447@1|root,COG4447@2|Bacteria,1VCI4@1239|Firmicutes,24CF6@186801|Clostridia,36N4E@31979|Clostridiaceae	186801|Clostridia	M	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,N_methyl
YHH1_k127_8370497_2	373994.Riv7116_0606	3.069e-32	132.0	2B09D@1|root,31SK9@2|Bacteria	2|Bacteria	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
YHH1_k127_8370497_1	665959.HMPREF1013_04214	3.45e-49	182.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,1ZFX8@1386|Bacillus	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH1_k127_8370497_0	1121104.AQXH01000001_gene1689	2.713e-55	197.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,1IQQC@117747|Sphingobacteriia	976|Bacteroidetes	P	Membrane protein TerC, possibly involved in tellurium resistance	-	-	-	-	-	-	-	-	-	-	-	-	TerC
YHH1_k127_8385389_0	1191523.MROS_0607	7.785e-91	311.0	COG0276@1|root,COG0276@2|Bacteria	2|Bacteria	H	ferrochelatase activity	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1540,iECS88_1305.ECS88_0472,iEcE24377_1341.EcE24377A_0515	Ferrochelatase
YHH1_k127_8385389_1	880073.Calab_3717	9.238e-67	235.0	COG1232@1|root,COG1232@2|Bacteria,2NQ1W@2323|unclassified Bacteria	2|Bacteria	H	Flavin containing amine oxidoreductase	hemG	-	1.14.19.9,1.3.3.15,1.3.3.4	ko:K00231,ko:K14266	ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130	M00121,M00789,M00790	R03222,R04178,R09570	RC00885,RC00949	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
YHH1_k127_8386268_0	945713.IALB_2249	5.614e-52	194.0	COG3264@1|root,COG3264@2|Bacteria	2|Bacteria	M	cellular water homeostasis	mscS-1	-	-	ko:K05802,ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.4	-	-	MS_channel,TM_helix
YHH1_k127_8386268_1	1191523.MROS_1543	1.855e-41	160.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
YHH1_k127_8386268_2	1158345.JNLL01000001_gene701	5.066e-16	87.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
YHH1_k127_8424597_0	945713.IALB_1918	1.972e-157	536.0	COG4797@1|root,COG4797@2|Bacteria	2|Bacteria	-	-	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
YHH1_k127_8436952_2	1095772.CAHH01000005_gene2315	6.575e-11	68.0	COG1041@1|root,COG1041@2|Bacteria,2I2EV@201174|Actinobacteria	201174|Actinobacteria	L	tRNA (guanine-N2-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8436952_0	945713.IALB_0790	2.15e-155	503.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	dapE	-	3.5.1.16,3.5.1.18	ko:K01436,ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YHH1_k127_8436952_1	484770.UFO1_3958	3.958e-48	193.0	COG4251@1|root,COG4251@2|Bacteria,1V0TU@1239|Firmicutes	1239|Firmicutes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
YHH1_k127_8437832_0	1191523.MROS_0140	1.847e-93	320.0	COG0248@1|root,COG0248@2|Bacteria	2|Bacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
YHH1_k127_8437832_1	945713.IALB_0227	2.247e-29	126.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	waaC	-	-	ko:K02841,ko:K02843,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH1_k127_8457227_0	1210908.HSB1_04500	3.536e-75	261.0	COG0434@1|root,arCOG01982@2157|Archaea,2XT9I@28890|Euryarchaeota,23T8W@183963|Halobacteria	183963|Halobacteria	S	photosystem I assembly BtpA	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
YHH1_k127_8457227_2	1216976.AX27061_0872	3.048e-06	60.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2VR0Y@28216|Betaproteobacteria,3T2Y3@506|Alcaligenaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	yiaD_1	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
YHH1_k127_8457227_1	1121930.AQXG01000004_gene2828	8.92e-12	73.0	COG2911@1|root,COG2911@2|Bacteria,4PPNA@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_847477_0	1121104.AQXH01000001_gene2028	2.961e-121	403.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH1_k127_847477_2	309807.SRU_0926	1.839e-43	173.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1FJ10@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YHH1_k127_847477_1	1191523.MROS_1251	2.676e-84	295.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH1_k127_8490504_3	1191523.MROS_2082	9.623e-05	55.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YHH1_k127_8490504_1	711393.AYRX01000021_gene1275	4.574e-25	121.0	COG1131@1|root,COG2936@1|root,COG1131@2|Bacteria,COG2936@2|Bacteria,2GN8P@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,Hydrolase_4,PepX_C,Peptidase_S15
YHH1_k127_8490504_0	485917.Phep_2038	1.78e-193	627.0	COG3591@1|root,COG3591@2|Bacteria,4NIMW@976|Bacteroidetes,1IQUI@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
YHH1_k127_8490504_2	1294265.JCM21738_4846	2.721e-19	91.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,1ZASY@1386|Bacillus	91061|Bacilli	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	vicX	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
YHH1_k127_8527540_1	1209989.TepiRe1_0530	5.194e-123	412.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42EWB@68295|Thermoanaerobacterales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
YHH1_k127_8527540_3	1121373.KB903620_gene2014	1.076e-06	56.0	COG5652@1|root,COG5652@2|Bacteria,4NXUQ@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	fjo27	-	-	-	-	-	-	-	-	-	-	-	VanZ
YHH1_k127_8527540_0	945713.IALB_3187	1.425e-127	421.0	COG0012@1|root,COG0012@2|Bacteria	2|Bacteria	J	GTP binding	ychF	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YHH1_k127_8527540_2	945713.IALB_0846	3.25e-08	59.0	COG1520@1|root,COG1572@1|root,COG3291@1|root,COG4733@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,Malectin,fn3
YHH1_k127_8566354_0	1191523.MROS_2112	3.017e-311	970.0	COG0060@1|root,COG0060@2|Bacteria	2|Bacteria	J	isoleucyl-tRNA aminoacylation	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YHH1_k127_8574079_2	1191523.MROS_1561	3.41e-69	250.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	pdxB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z3582	2-Hacid_dh,2-Hacid_dh_C,DUF3410
YHH1_k127_8574079_1	761193.Runsl_1587	1.285e-99	345.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,47MD4@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
YHH1_k127_8574079_0	1519464.HY22_13130	1.563e-118	402.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH1_k127_8574079_3	1121930.AQXG01000002_gene2119	0.0003513	52.0	COG1472@1|root,COG1472@2|Bacteria,4NIBJ@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_3
YHH1_k127_8574504_0	338963.Pcar_0743	2.335e-05	56.0	COG3087@1|root,COG3087@2|Bacteria,1N320@1224|Proteobacteria,42UIE@68525|delta/epsilon subdivisions,2WR4W@28221|Deltaproteobacteria,43SPW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
YHH1_k127_8580939_0	1150600.ADIARSV_2737	4.868e-148	488.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1IP46@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YHH1_k127_859501_2	945713.IALB_0903	1.691e-36	144.0	COG0244@1|root,COG0244@2|Bacteria	2|Bacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02864,ko:K02935	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
YHH1_k127_859501_1	1191523.MROS_0224	1.409e-39	155.0	COG0222@1|root,COG0222@2|Bacteria	2|Bacteria	J	mitochondrial gene expression	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
YHH1_k127_859501_0	639282.DEFDS_1779	0.0	1283.0	COG0085@1|root,COG0085@2|Bacteria,2GEW9@200930|Deferribacteres	200930|Deferribacteres	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH1_k127_859501_3	945713.IALB_0906	2.832e-35	135.0	COG0086@1|root,COG0086@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH1_k127_8595122_0	518766.Rmar_1268	9.516e-131	425.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1FIPP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH1_k127_8595122_1	762903.Pedsa_2904	3.24e-45	170.0	COG4232@1|root,COG4232@2|Bacteria,4PMPN@976|Bacteroidetes,1ISJ4@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
YHH1_k127_8673549_2	945713.IALB_2662	2.679e-64	236.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT,PMT_2,TPR_19
YHH1_k127_8673549_0	518766.Rmar_1858	3.921e-155	494.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1FIS7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YHH1_k127_8673549_3	1194972.MVAC_05292	3.751e-05	56.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH1_k127_8673549_1	1123276.KB893276_gene2365	1.487e-78	269.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,47UDR@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_8676003_2	1353529.M899_0017	1.183e-09	64.0	COG0566@1|root,COG0566@2|Bacteria,1QQ53@1224|Proteobacteria,42R2I@68525|delta/epsilon subdivisions,2WWFE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	SpoU rRNA Methylase family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
YHH1_k127_8676003_1	1117379.BABA_24040	1.543e-54	207.0	COG2733@1|root,COG2733@2|Bacteria,1TS8F@1239|Firmicutes,4HC8U@91061|Bacilli,1ZCND@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
YHH1_k127_8676003_0	596152.DesU5LDRAFT_2536	1.89e-57	215.0	COG0500@1|root,COG2226@2|Bacteria,1QXUA@1224|Proteobacteria,42QNQ@68525|delta/epsilon subdivisions,2WMN4@28221|Deltaproteobacteria,2MDTC@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YHH1_k127_8688287_1	331678.Cphamn1_2419	0.0001056	49.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_18,HTH_3,HTH_Tnp_4,Peripla_BP_3
YHH1_k127_8688287_0	247490.KSU1_C0449	4.003e-69	256.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
YHH1_k127_8690131_3	1173022.Cri9333_0049	3.178e-17	96.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7TU@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_8
YHH1_k127_8690131_1	1293048.CBMB010000003_gene1428	3.295e-21	109.0	COG0784@1|root,COG3413@1|root,arCOG02276@2157|Archaea,arCOG02386@2157|Archaea,2XTCA@28890|Euryarchaeota,23S6Z@183963|Halobacteria	183963|Halobacteria	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	BAT,GAF_2,HTH_10,Response_reg
YHH1_k127_8690131_0	935863.AWZR01000005_gene2411	2.333e-126	415.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1X36D@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_C,Ala_racemase_N
YHH1_k127_8690131_2	1191523.MROS_1334	3.568e-21	98.0	COG0745@1|root,COG0745@2|Bacteria	1191523.MROS_1334|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8690131_4	1384056.N787_05465	6.409e-05	54.0	COG3121@1|root,COG3121@2|Bacteria,1R5EM@1224|Proteobacteria,1SHIR@1236|Gammaproteobacteria,1XAAN@135614|Xanthomonadales	135614|Xanthomonadales	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8696441_1	196367.JNFG01000004_gene5562	7.207e-63	219.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,1K21C@119060|Burkholderiaceae	28216|Betaproteobacteria	NT	chemotaxis protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
YHH1_k127_8696441_0	395494.Galf_2121	1.844e-227	706.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,44V4J@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp
YHH1_k127_8709127_1	153721.MYP_4007	2.038e-26	117.0	COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,47NWX@768503|Cytophagia	976|Bacteroidetes	E	GDSL family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
YHH1_k127_8709127_0	1191523.MROS_1635	3.047e-302	943.0	COG0046@1|root,COG0046@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH1_k127_8710480_2	329726.AM1_1393	4.476e-11	70.0	2EJ3X@1|root,33CV7@2|Bacteria,1GAPS@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8710480_0	1121943.KB899989_gene3250	2.719e-87	302.0	COG1432@1|root,COG1432@2|Bacteria,1RCRF@1224|Proteobacteria	1224|Proteobacteria	K	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD,NYN
YHH1_k127_8720899_1	1408813.AYMG01000032_gene5238	1.255e-45	186.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,F5_F8_type_C,PKD
YHH1_k127_8720899_5	945713.IALB_2584	2.051e-12	80.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
YHH1_k127_8720899_0	314230.DSM3645_09772	1.995e-57	203.0	COG2947@1|root,COG2947@2|Bacteria,2IZM3@203682|Planctomycetes	203682|Planctomycetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
YHH1_k127_8720899_2	319225.Plut_0230	7.202e-34	135.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3,AhpC-TSA
YHH1_k127_8720899_3	1499967.BAYZ01000082_gene1016	1.038e-27	122.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	yihX	GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.10,3.1.3.104,3.8.1.2	ko:K01560,ko:K07025,ko:K20866,ko:K21063	ko00010,ko00361,ko00625,ko00740,ko01100,ko01110,ko01120,map00010,map00361,map00625,map00740,map01100,map01110,map01120	M00125	R00947,R05287,R07280	RC00017,RC00078,RC00697	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
YHH1_k127_8720899_4	945713.IALB_2658	1.463e-14	83.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH1_k127_8736990_0	335543.Sfum_3732	1.237e-268	829.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,42UK8@68525|delta/epsilon subdivisions,2WQG7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
YHH1_k127_8736990_1	56780.SYN_02434	6.538e-18	83.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.5.1.106	ko:K15357	ko00760,ko01120,map00760,map01120	M00622	R09126	RC00323,RC02431	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_3,Abhydrolase_6,Hydrolase_4
YHH1_k127_8737383_0	1385512.N784_03480	2.924e-94	319.0	COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,2Y9NV@289201|Pontibacillus	91061|Bacilli	P	Transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
YHH1_k127_8737383_2	1121459.AQXE01000001_gene2798	2.751e-09	68.0	COG2510@1|root,COG2510@2|Bacteria,1QV9N@1224|Proteobacteria,43BNU@68525|delta/epsilon subdivisions,2X704@28221|Deltaproteobacteria,2MHA4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_8737383_1	1168034.FH5T_06340	5.606e-68	244.0	COG1629@1|root,COG4771@2|Bacteria,4NVEJ@976|Bacteroidetes	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
YHH1_k127_8753581_3	1304888.ATWF01000002_gene343	1.288e-33	134.0	COG0642@1|root,COG2205@2|Bacteria	1304888.ATWF01000002_gene343|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8753581_4	65393.PCC7424_4021	4.354e-09	64.0	COG4251@1|root,COG4251@2|Bacteria,1GHC4@1117|Cyanobacteria,3KHA2@43988|Cyanothece	1117|Cyanobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF,HATPase_c,HisKA,Hpt,PAS_2,PAS_3,PAS_9,PHY,Response_reg
YHH1_k127_8753581_1	1499967.BAYZ01000182_gene4443	2.577e-92	316.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,2NR1F@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HD_5,HisKA,PAS_4,Response_reg
YHH1_k127_8753581_0	502025.Hoch_3647	4.534e-185	587.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YHH1_k127_8753581_2	1499967.BAYZ01000193_gene3921	2.188e-81	283.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
YHH1_k127_8754283_0	246969.TAM4_1617	7.171e-19	100.0	COG1240@1|root,COG3291@1|root,arCOG02546@2157|Archaea,arCOG06472@2157|Archaea	2157|Archaea	H	von Willebrand factor, type A	chlID	-	3.2.1.4,6.6.1.1	ko:K01179,ko:K03404,ko:K03405	ko00500,ko00860,ko01100,ko01110,map00500,map00860,map01100,map01110	-	R03877,R06200,R11307,R11308	RC01012	ko00000,ko00001,ko01000	-	GH5,GH9	-	AAA_5,Mg_chelatase,PKD,VWA,VWA_2
YHH1_k127_8754283_1	1279009.ADICEAN_02186	5.133e-16	91.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
YHH1_k127_8768874_1	1191523.MROS_2609	0.0002714	54.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,PSII_BNR
YHH1_k127_8768874_0	1242864.D187_002256	6.075e-26	124.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42Z9H@68525|delta/epsilon subdivisions,2WUIK@28221|Deltaproteobacteria,2YUAX@29|Myxococcales	28221|Deltaproteobacteria	K	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
YHH1_k127_8768874_2	1121930.AQXG01000007_gene489	0.000285	48.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Lyase_8,Lyase_8_C,Lyase_8_N,Peptidase_S8
YHH1_k127_877592_3	323850.Shew_2739	2.27e-16	81.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,1RSN2@1236|Gammaproteobacteria,2QAQP@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
YHH1_k127_877592_1	945713.IALB_0227	2.794e-57	214.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	waaC	-	-	ko:K02841,ko:K02843,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH1_k127_877592_2	1348657.M622_10900	1.039e-24	111.0	COG2020@1|root,COG2020@2|Bacteria,1PPQV@1224|Proteobacteria,2VR3S@28216|Betaproteobacteria,2KYVU@206389|Rhodocyclales	206389|Rhodocyclales	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	-
YHH1_k127_877592_0	1232410.KI421419_gene2512	4.157e-78	277.0	COG3875@1|root,COG3875@2|Bacteria,1R79Y@1224|Proteobacteria,42PGD@68525|delta/epsilon subdivisions,2WMB6@28221|Deltaproteobacteria,43T90@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
YHH1_k127_877592_4	27923.ML085912a-PA	1.773e-08	64.0	KOG2177@1|root,KOG2177@2759|Eukaryota,38F95@33154|Opisthokonta,3BA7J@33208|Metazoa	33208|Metazoa	O	miRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YHH1_k127_8784045_1	1187851.A33M_2392	1.759e-14	73.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria,3FCSH@34008|Rhodovulum	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH1_k127_8784045_0	856793.MICA_2142	1.165e-310	957.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,4BPIN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH1_k127_8805824_1	768670.Calni_0625	2.416e-69	239.0	COG1592@1|root,COG1592@2|Bacteria,2GFEX@200930|Deferribacteres	200930|Deferribacteres	C	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YHH1_k127_8805824_0	28072.Nos7524_0294	6.638e-137	449.0	COG1785@1|root,COG1785@2|Bacteria,1G3F0@1117|Cyanobacteria,1HQ9I@1161|Nostocales	1117|Cyanobacteria	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
YHH1_k127_8808345_0	1296416.JACB01000029_gene4196	3.065e-178	576.0	COG3422@1|root,COG3422@2|Bacteria,4NHE4@976|Bacteroidetes,1I0UZ@117743|Flavobacteriia,2YHEU@290174|Aquimarina	976|Bacteroidetes	S	double-strand break repair	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8808345_2	1296416.JACB01000029_gene4196	2.378e-33	136.0	COG3422@1|root,COG3422@2|Bacteria,4NHE4@976|Bacteroidetes,1I0UZ@117743|Flavobacteriia,2YHEU@290174|Aquimarina	976|Bacteroidetes	S	double-strand break repair	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8808345_1	700598.Niako_0472	2.472e-42	159.0	COG3299@1|root,COG3299@2|Bacteria,4NF69@976|Bacteroidetes,1INRV@117747|Sphingobacteriia	976|Bacteroidetes	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
YHH1_k127_8824633_1	118168.MC7420_6824	5.237e-30	126.0	COG0610@1|root,COG2852@1|root,COG0610@2|Bacteria,COG2852@2|Bacteria,1G3YH@1117|Cyanobacteria,1HA5G@1150|Oscillatoriales	1117|Cyanobacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
YHH1_k127_8824633_2	1223410.KN050846_gene2812	7.751e-06	57.0	COG1572@1|root,COG2010@1|root,COG1572@2|Bacteria,COG2010@2|Bacteria,4NJ3E@976|Bacteroidetes,1IK72@117743|Flavobacteriia	976|Bacteroidetes	C	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
YHH1_k127_8824633_0	1121129.KB903360_gene3644	1.992e-156	502.0	COG1042@1|root,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,2FNSJ@200643|Bacteroidia,22WFU@171551|Porphyromonadaceae	976|Bacteroidetes	C	CoA ligase	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
YHH1_k127_8849252_0	517418.Ctha_2258	8.214e-47	182.0	COG4288@1|root,COG4288@2|Bacteria,1FE3D@1090|Chlorobi	1090|Chlorobi	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,LTD
YHH1_k127_8849252_1	945713.IALB_2158	2.884e-39	155.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HD_5,HisKA,PAS,PAS_8,PAS_9,Reg_prop,Response_reg,Y_Y_Y
YHH1_k127_8873074_3	1027273.GZ77_03000	5.552e-17	83.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	response regulator	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c_2,Response_reg,SpoIIE
YHH1_k127_8873074_1	344747.PM8797T_03384	9.1e-77	267.0	COG3752@1|root,COG3752@2|Bacteria,2IZ0I@203682|Planctomycetes	203682|Planctomycetes	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
YHH1_k127_8873074_0	472759.Nhal_0304	7.12e-120	394.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1WWIX@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
YHH1_k127_8873074_2	1232437.KL661966_gene3131	4.422e-32	128.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,42N4S@68525|delta/epsilon subdivisions,2WJXX@28221|Deltaproteobacteria,2MIKA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
YHH1_k127_8905338_2	857293.CAAU_0235	3.773e-32	132.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,36DN2@31979|Clostridiaceae	186801|Clostridia	D	Capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA
YHH1_k127_8905338_3	1122176.KB903545_gene864	8.313e-05	52.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,1IU2R@117747|Sphingobacteriia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_8905338_0	945713.IALB_2618	5.523e-229	717.0	COG3033@1|root,COG3033@2|Bacteria	2|Bacteria	E	tryptophanase activity	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
YHH1_k127_8905338_1	1284352.AOIG01000009_gene1709	1.04e-45	181.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_tran_WbsX,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
YHH1_k127_8908683_1	408672.NBCG_04327	2.021e-05	57.0	COG1316@1|root,COG1316@2|Bacteria,2IAW9@201174|Actinobacteria,4DTHV@85009|Propionibacteriales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
YHH1_k127_8908683_0	1234409.C683_0395	1.72e-09	60.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,4AZH1@81852|Enterococcaceae	91061|Bacilli	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:2001065	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
YHH1_k127_8920404_1	1227739.Hsw_3174	3.375e-68	237.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
YHH1_k127_8920404_0	880073.Calab_1785	1.592e-118	389.0	COG0709@1|root,COG1104@1|root,COG0709@2|Bacteria,COG1104@2|Bacteria,2NNVR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	selD	-	2.7.9.3,2.8.1.7	ko:K01008,ko:K04487	ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122	-	R03595,R07460,R11528,R11529	RC00002,RC01789,RC02313,RC02878	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	AIRS,AIRS_C,Aminotran_5
YHH1_k127_8924434_1	1191523.MROS_1536	3.079e-11	76.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23	ko:K01186,ko:K01197,ko:K05988,ko:K11931,ko:K18197	ko00500,ko00511,ko00531,ko00600,ko01100,ko02026,ko04142,map00500,map00511,map00531,map00600,map01100,map02026,map04142	M00076,M00077	R04018,R07824,R07825,R10905,R11309	RC00028,RC00077	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	GH33,GH66,PL11	-	DUF1349,GHL10,Glyco_hydro_20b,Laminin_G_3,NAGidase,fn3
YHH1_k127_8924434_2	1298593.TOL_2834	0.000249	53.0	COG1874@1|root,COG1874@2|Bacteria,1QTP8@1224|Proteobacteria,1RXTA@1236|Gammaproteobacteria,1XMY8@135619|Oceanospirillales	135619|Oceanospirillales	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
YHH1_k127_8924434_0	398527.Bphyt_7185	2.416e-70	241.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,2VR7G@28216|Betaproteobacteria,1K1RE@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YHH1_k127_8938056_6	1408433.JHXV01000006_gene2790	1.26e-26	109.0	COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes,1I1II@117743|Flavobacteriia,2PARM@246874|Cryomorphaceae	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
YHH1_k127_8938056_4	926549.KI421517_gene828	1.517e-77	265.0	COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,47PIW@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
YHH1_k127_8938056_0	1122134.KB893650_gene31	2.886e-151	484.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,1RX6Z@1236|Gammaproteobacteria,1XRR2@135619|Oceanospirillales	135619|Oceanospirillales	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
YHH1_k127_8938056_5	1174528.JH992891_gene352	1.818e-68	241.0	COG1878@1|root,COG1878@2|Bacteria	2|Bacteria	S	arylformamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YHH1_k127_8938056_1	1384054.N790_04740	1.545e-149	485.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,1RPY3@1236|Gammaproteobacteria,1X3FQ@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
YHH1_k127_8938056_2	1278073.MYSTI_00934	5.136e-146	477.0	COG0654@1|root,COG0654@2|Bacteria,1R7UC@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114	1.14.13.224,1.14.13.9	ko:K00486,ko:K20090	ko00380,ko00404,ko01100,ko01130,ko02024,map00380,map00404,map01100,map01130,map02024	M00038,M00808	R01960,R11132,R11135,R11373,R11374	RC00046,RC03365	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
YHH1_k127_8938056_3	1519464.HY22_08035	1.224e-107	369.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11,4.1.1.45	ko:K00453,ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R00678,R04323	RC00356,RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
YHH1_k127_8940966_0	1191523.MROS_0349	9.08e-155	496.0	COG0148@1|root,COG0148@2|Bacteria	2|Bacteria	G	phosphopyruvate hydratase activity	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
YHH1_k127_8940966_1	945713.IALB_1675	3.296e-115	387.0	COG1109@1|root,COG1109@2|Bacteria	2|Bacteria	G	phosphoglucosamine mutase activity	glmM	-	5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YHH1_k127_8940966_2	517418.Ctha_2621	9.713e-05	50.0	COG0168@1|root,COG0168@2|Bacteria,1FETI@1090|Chlorobi	1090|Chlorobi	P	H transporting two-sector ATPase	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
YHH1_k127_8967375_2	1121104.AQXH01000001_gene1689	5.529e-33	132.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,1IQQC@117747|Sphingobacteriia	976|Bacteroidetes	P	Membrane protein TerC, possibly involved in tellurium resistance	-	-	-	-	-	-	-	-	-	-	-	-	TerC
YHH1_k127_8967375_1	1121451.DESAM_21665	1.865e-53	201.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,43BJZ@68525|delta/epsilon subdivisions,2X6XU@28221|Deltaproteobacteria,2MBAK@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
YHH1_k127_8967375_0	440512.C211_03730	5.763e-54	194.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
YHH1_k127_896957_4	264198.Reut_A2888	1.587e-06	61.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VIVR@28216|Betaproteobacteria,1K2PA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114,ko:K16257	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YHH1_k127_896957_5	1122611.KB903968_gene2277	3.187e-06	59.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Glyco_hyd_101C,Glyco_hydro_101,Glyco_hydro_43,NPCBM,NPCBM_assoc,RicinB_lectin_2
YHH1_k127_896957_3	497964.CfE428DRAFT_2307	8.503e-07	60.0	COG0810@1|root,COG0810@2|Bacteria,46WNS@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH1_k127_896957_1	1316936.K678_01883	2.187e-15	81.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,2JRTS@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0694 Thioredoxin-like proteins and domains	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
YHH1_k127_896957_2	379066.GAU_0167	1.862e-11	70.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
YHH1_k127_896957_0	313606.M23134_00239	1.305e-136	439.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH1_k127_8982188_0	264732.Moth_0371	2.096e-61	222.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,249II@186801|Clostridia,42FVW@68295|Thermoanaerobacterales	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH1_k127_8989377_1	525904.Tter_2147	9.78e-99	336.0	COG2377@1|root,COG2377@2|Bacteria,2NNMN@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	2.7.1.170,4.2.1.126	ko:K07106,ko:K09001	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032	AnmK
YHH1_k127_8989377_0	331678.Cphamn1_0800	0.0	1208.0	COG0209@1|root,COG0209@2|Bacteria,1FD9Z@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC
YHH1_k127_9034297_0	1191523.MROS_2344	4.563e-15	89.0	COG2730@1|root,COG3866@1|root,COG4677@1|root,COG2730@2|Bacteria,COG3866@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	pel3	-	3.2.1.78,3.2.1.89	ko:K01218,ko:K01224	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Cellulase,F5_F8_type_C,Pectinesterase
YHH1_k127_9047459_0	518766.Rmar_2754	1.844e-179	587.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1FIP1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
YHH1_k127_9060518_1	483219.LILAB_25580	3.599e-64	225.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2YVCP@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
YHH1_k127_9060518_3	2045.KR76_14740	9.946e-05	53.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4DQSP@85009|Propionibacteriales	201174|Actinobacteria	E	Shikimate dehydrogenase substrate binding domain	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2552c	Shikimate_DH,Shikimate_dh_N
YHH1_k127_9060518_2	1123508.JH636439_gene1387	7.923e-15	86.0	COG0703@1|root,COG0703@2|Bacteria,2J038@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
YHH1_k127_9060518_0	1463856.JOHY01000032_gene2960	4.331e-75	260.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	dapC	-	2.6.1.1,2.6.1.17	ko:K00812,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_9069489_0	1232410.KI421415_gene2999	5.436e-155	497.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,43TJW@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH1_k127_9074182_1	477974.Daud_1094	2.178e-90	318.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,260IK@186807|Peptococcaceae	186801|Clostridia	J	Elongation factor Tu domain 2	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
YHH1_k127_9074182_0	1144275.COCOR_03213	5.04e-102	350.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2YU5T@29|Myxococcales	28221|Deltaproteobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
YHH1_k127_9074182_2	243231.GSU0779	1.958e-12	72.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42P2Q@68525|delta/epsilon subdivisions,2WKC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	fdnI	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1061	NrfD
YHH1_k127_9087623_0	575540.Isop_1978	2.164e-91	327.0	COG2755@1|root,COG2755@2|Bacteria,2IWTR@203682|Planctomycetes	203682|Planctomycetes	E	sialic acid-specific 9-O-acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
YHH1_k127_9101572_1	926562.Oweho_1031	1.628e-53	203.0	COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,1HY7M@117743|Flavobacteriia	976|Bacteroidetes	E	Aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
YHH1_k127_9101572_2	945713.IALB_0951	1.641e-23	111.0	29C3H@1|root,32VP8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9101572_0	1191523.MROS_0851	1.07e-60	217.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2
YHH1_k127_9136043_0	1191523.MROS_0046	1.736e-119	392.0	COG0142@1|root,COG0142@2|Bacteria	2|Bacteria	H	isoprenoid biosynthetic process	ispB	GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	iYL1228.KPN_03597,ic_1306.c3945	polyprenyl_synt
YHH1_k127_9136043_1	945713.IALB_1458	2.699e-87	296.0	COG0805@1|root,COG0805@2|Bacteria	2|Bacteria	U	protein transport	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YHH1_k127_9136043_2	756272.Plabr_0961	7.598e-38	151.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31,WbqC
YHH1_k127_9148504_2	1382359.JIAL01000001_gene2623	1.751e-49	184.0	COG0842@1|root,COG0842@2|Bacteria,3Y2S4@57723|Acidobacteria,2JISC@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
YHH1_k127_9148504_4	313606.M23134_00203	1.006e-28	128.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,47XQN@768503|Cytophagia	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
YHH1_k127_9148504_3	234267.Acid_4378	6.158e-40	156.0	COG2322@1|root,COG2322@2|Bacteria,3Y5H4@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
YHH1_k127_9148504_1	1340493.JNIF01000004_gene1029	5.088e-60	214.0	COG3880@1|root,COG3880@2|Bacteria,3Y2KG@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
YHH1_k127_9148504_0	1144275.COCOR_06606	6.182e-97	340.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	iron-sulfur binding	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YHH1_k127_9152540_2	349521.HCH_06953	2.733e-40	169.0	COG1506@1|root,COG1506@2|Bacteria,1P7CR@1224|Proteobacteria	1224|Proteobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9152540_3	1382306.JNIM01000001_gene124	1.911e-18	98.0	28HQ3@1|root,2Z7XW@2|Bacteria,2G9Q4@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
YHH1_k127_9152540_1	246197.MXAN_6297	3.734e-83	281.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,2YURC@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YHH1_k127_9152540_0	1191523.MROS_2492	6.963e-93	312.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH1_k127_9153066_1	471854.Dfer_1867	1.249e-10	75.0	COG2374@1|root,COG4886@1|root,COG2374@2|Bacteria,COG4886@2|Bacteria,4NF17@976|Bacteroidetes,47N86@768503|Cytophagia	976|Bacteroidetes	M	Mycoplasma protein of unknown function, DUF285	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DUF285,LRR_5
YHH1_k127_9153066_0	28072.Nos7524_1819	6.225e-28	131.0	COG1404@1|root,COG1572@1|root,COG2374@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG4932@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,1GIN1@1117|Cyanobacteria,1HNE9@1161|Nostocales	1117|Cyanobacteria	MOQ	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,PPC,Peptidase_S8,SdrD_B
YHH1_k127_916454_0	945713.IALB_0756	1.741e-23	117.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	CP_1076	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Autotransporter,DUF1929,Glyoxal_oxid_N,PA14
YHH1_k127_9198121_1	880073.Calab_0921	2.001e-05	57.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
YHH1_k127_9198121_0	402880.MmarC5_0829	9.837e-12	78.0	COG3291@1|root,arCOG03396@2157|Archaea	2157|Archaea	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	A2M_comp,CARDB,Prenyltrans,SQHop_cyclase_C,Thiol-ester_cl
YHH1_k127_920834_3	1229780.BN381_130324	8.924e-06	58.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
YHH1_k127_920834_1	983917.RGE_12110	2.493e-23	115.0	COG1216@1|root,COG1216@2|Bacteria,1RBZ4@1224|Proteobacteria,2VQNN@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
YHH1_k127_920834_0	1131462.DCF50_p1142	1.491e-70	253.0	COG0438@1|root,COG0438@2|Bacteria,1VC02@1239|Firmicutes,24NFM@186801|Clostridia,262QW@186807|Peptococcaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
YHH1_k127_9225861_0	945713.IALB_1631	6.634e-215	679.0	COG1008@1|root,COG1008@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
YHH1_k127_9225861_1	1191523.MROS_2371	4.439e-43	162.0	COG1009@1|root,COG1009@2|Bacteria	2|Bacteria	CP	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
YHH1_k127_9260098_0	515635.Dtur_1286	1.825e-73	266.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
YHH1_k127_9260098_1	330214.NIDE3027	1.17e-28	119.0	COG0463@1|root,COG0463@2|Bacteria,3J0M5@40117|Nitrospirae	40117|Nitrospirae	M	biosynthesis glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_9270513_2	85643.Tmz1t_3001	2.982e-41	155.0	COG0011@1|root,COG0011@2|Bacteria,1N0UT@1224|Proteobacteria,2VW0K@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
YHH1_k127_9270513_0	945713.IALB_0415	1.049e-184	618.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9270513_1	518766.Rmar_0129	9.797e-82	279.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,1FJ7Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
YHH1_k127_9272539_3	926562.Oweho_2087	5.724e-05	46.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia,2PAXX@246874|Cryomorphaceae	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit III	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
YHH1_k127_9272539_0	929556.Solca_1394	1.635e-166	537.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
YHH1_k127_9272539_1	1120965.AUBV01000012_gene1505	1.455e-18	94.0	COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia	976|Bacteroidetes	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
YHH1_k127_9272539_2	1123057.P872_17525	4.18e-06	49.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
YHH1_k127_9280493_1	1227268.HMPREF1552_01416	1.905e-17	90.0	COG2885@1|root,COG2885@2|Bacteria,37AF9@32066|Fusobacteria	32066|Fusobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
YHH1_k127_9280493_0	1519464.HY22_08765	4.713e-35	142.0	COG0357@1|root,COG0357@2|Bacteria,1FE2G@1090|Chlorobi	1090|Chlorobi	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
YHH1_k127_9280493_2	1356852.N008_08295	2.594e-15	79.0	COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,47KD5@768503|Cytophagia	976|Bacteroidetes	M	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
YHH1_k127_9288114_2	340177.Cag_0168	1.656e-56	201.0	COG1335@1|root,COG1335@2|Bacteria,1FE0F@1090|Chlorobi	1090|Chlorobi	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
YHH1_k127_9288114_4	1191523.MROS_1615	3.18e-08	64.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,TPR_1,TPR_16,TPR_19,TPR_7,TPR_8
YHH1_k127_9288114_0	945713.IALB_0615	2.601e-216	681.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.12	ko:K00694,ko:K00786	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glyco_tranf_2_3
YHH1_k127_9288114_1	880073.Calab_3385	6.861e-110	367.0	COG2204@1|root,COG2204@2|Bacteria,2NQDH@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	fhlA	-	-	ko:K03413,ko:K13589	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506,M00512	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_9298596_1	1515613.HQ37_02540	1.099e-45	169.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,2FMU1@200643|Bacteroidia,22W2B@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YHH1_k127_9298596_0	1191523.MROS_0484	2.818e-227	732.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug,TonB_dep_Rec
YHH1_k127_9334582_1	755732.Fluta_0372	4.17e-32	135.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
YHH1_k127_9334582_0	517417.Cpar_0845	6.878e-236	739.0	COG4108@1|root,COG4108@2|Bacteria,1FEXE@1090|Chlorobi	1090|Chlorobi	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
YHH1_k127_9335612_0	1123276.KB893301_gene4324	1.73e-69	264.0	COG1044@1|root,COG5295@1|root,COG1044@2|Bacteria,COG5295@2|Bacteria,4NMJW@976|Bacteroidetes,47XBE@768503|Cytophagia	976|Bacteroidetes	UW	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,Peptidase_S74
YHH1_k127_9335612_2	1123276.KB893290_gene5211	1.384e-13	77.0	2DR38@1|root,339ZC@2|Bacteria,4NY0S@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9335612_1	996637.SGM_2150	3.345e-16	88.0	COG2197@1|root,COG2197@2|Bacteria,2GJHH@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator receiver	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
YHH1_k127_9339237_1	1237149.C900_05913	1.124e-44	171.0	COG4677@1|root,COG4704@1|root,COG5184@1|root,COG5492@1|root,COG4677@2|Bacteria,COG4704@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4PN9Q@976|Bacteroidetes,47Y9H@768503|Cytophagia	976|Bacteroidetes	DZ	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
YHH1_k127_9339237_2	1121930.AQXG01000004_gene2869	1.357e-21	110.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	prtA	-	3.2.1.23,3.4.24.40	ko:K01190,ko:K01406,ko:K07004,ko:K13277	ko00052,ko00511,ko00600,ko01100,ko01503,ko02024,map00052,map00511,map00600,map01100,map01503,map02024	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Gram_pos_anchor,HemolysinCabind,PA,Peptidase_S8,SLH,fn3_5
YHH1_k127_9339237_0	357809.Cphy_1688	1.316e-89	317.0	COG4447@1|root,COG4447@2|Bacteria,1UU3Y@1239|Firmicutes,24C6F@186801|Clostridia	186801|Clostridia	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9342968_1	1191523.MROS_0598	2.459e-74	258.0	COG1459@1|root,COG1459@2|Bacteria	2|Bacteria	U	protein transport across the cell outer membrane	pilC2	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH1_k127_9342968_2	1121104.AQXH01000001_gene1024	5.608e-15	80.0	2BWJ4@1|root,2ZMM0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9342968_0	1124780.ANNU01000048_gene2129	8.062e-115	377.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
YHH1_k127_9369593_2	945713.IALB_2692	1.215e-26	128.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	BetaGal_dom4_5,F5_F8_type_C
YHH1_k127_9369593_1	1300150.EMQU_0072	2.981e-51	200.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,4B07U@81852|Enterococcaceae	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YHH1_k127_9369593_0	1191523.MROS_2462	1.717e-176	564.0	COG1972@1|root,COG1972@2|Bacteria	2|Bacteria	F	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	yeiM	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
YHH1_k127_9386026_0	1191523.MROS_2371	5.635e-183	585.0	COG1009@1|root,COG1009@2|Bacteria	2|Bacteria	CP	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
YHH1_k127_9398912_0	945713.IALB_0300	9.237e-267	852.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N,Response_reg,SpoIIE
YHH1_k127_940322_0	1121904.ARBP01000030_gene1930	5.84e-120	392.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47K8C@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YHH1_k127_940322_1	1536774.H70357_29815	1.279e-43	164.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_9410282_1	517418.Ctha_2667	3.259e-08	66.0	COG0708@1|root,COG0708@2|Bacteria,1FFH9@1090|Chlorobi	1090|Chlorobi	L	Exodeoxyribonuclease III	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9410282_0	313603.FB2170_10259	8.049e-35	141.0	2ETC6@1|root,33KW3@2|Bacteria,4P061@976|Bacteroidetes,1I8FX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9421539_0	1185876.BN8_01660	1.253e-65	244.0	COG1874@1|root,COG2374@1|root,COG2755@1|root,COG4625@1|root,COG1874@2|Bacteria,COG2374@2|Bacteria,COG2755@2|Bacteria,COG4625@2|Bacteria,4NI5S@976|Bacteroidetes,47NAE@768503|Cytophagia	976|Bacteroidetes	G	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_5,Calx-beta,Exo_endo_phos,He_PIG,LTD,VCBS
YHH1_k127_9436289_0	945713.IALB_2868	6.661e-239	746.0	COG2986@1|root,COG2986@2|Bacteria	2|Bacteria	E	ammonia-lyase activity	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
YHH1_k127_9444429_2	1121405.dsmv_1720	3.455e-10	64.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,2MHT7@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
YHH1_k127_9444429_0	1191523.MROS_0612	1.863e-106	360.0	COG0373@1|root,COG0373@2|Bacteria	2|Bacteria	H	glutamyl-tRNA reductase activity	hemA	GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040	1.2.1.70	ko:K02407,ko:K02492	ko00860,ko01100,ko01110,ko01120,ko02040,map00860,map01100,map01110,map01120,map02040	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000,ko02035	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
YHH1_k127_9444429_1	517418.Ctha_2290	1.799e-58	208.0	COG0181@1|root,COG0181@2|Bacteria,1FDJV@1090|Chlorobi	1090|Chlorobi	F	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
YHH1_k127_9480958_1	1123057.P872_04430	4.936e-17	93.0	COG2885@1|root,COG2885@2|Bacteria,4NI1Y@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2,OmpA
YHH1_k127_9489128_0	1501230.ET33_13205	3.277e-148	500.0	COG1874@1|root,COG1874@2|Bacteria,1UIWU@1239|Firmicutes,4HCA7@91061|Bacilli,26UV7@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
YHH1_k127_9489128_1	880073.Calab_0806	1.292e-86	291.0	COG1351@1|root,COG1351@2|Bacteria,2NPQ2@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
YHH1_k127_9509364_0	1123276.KB893301_gene4168	2.632e-87	301.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,47Q5S@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2,TPR_8
YHH1_k127_9509364_3	881621.LIV_2695	3.683e-20	94.0	2E5AU@1|root,3302Y@2|Bacteria,1VB5Y@1239|Firmicutes,4HPUD@91061|Bacilli,26KPZ@186820|Listeriaceae	91061|Bacilli	S	Src homology 3 domains	-	-	-	-	-	-	-	-	-	-	-	-	SH3_1,SH3_2
YHH1_k127_9509364_1	861299.J421_2168	3.278e-74	258.0	COG0454@1|root,COG0456@2|Bacteria,1ZTIN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9509364_2	518766.Rmar_2635	4.857e-60	225.0	COG1293@1|root,COG1293@2|Bacteria,4NGP5@976|Bacteroidetes,1FJ0X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
YHH1_k127_9516921_0	593750.Metfor_1602	3.935e-140	458.0	COG1373@1|root,arCOG03167@2157|Archaea,2Y2NX@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_9516921_1	1907.SGLAU_01645	0.0001892	51.0	COG1053@1|root,COG1413@1|root,COG1053@2|Bacteria,COG1413@2|Bacteria,2GPN8@201174|Actinobacteria	201174|Actinobacteria	C	fumarate reductase	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Cohesin_HEAT,FAD_binding_2,HEAT_2,Succ_DH_flav_C
YHH1_k127_9538747_1	861299.J421_4474	3.441e-58	220.0	2FK3F@1|root,34BRJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9538747_0	518766.Rmar_0925	3.834e-78	270.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
YHH1_k127_9547067_1	404589.Anae109_3444	2.732e-54	197.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,42P8E@68525|delta/epsilon subdivisions,2WIXT@28221|Deltaproteobacteria,2Z3J1@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
YHH1_k127_9547067_0	1120960.ATXG01000001_gene650	1.036e-66	237.0	COG0095@1|root,COG0095@2|Bacteria,2GJV5@201174|Actinobacteria,4FKRX@85023|Microbacteriaceae	201174|Actinobacteria	H	biotin lipoate A B protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YHH1_k127_9548073_1	762984.HMPREF9445_02260	2.488e-31	132.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,2FM91@200643|Bacteroidia,4APBS@815|Bacteroidaceae	976|Bacteroidetes	F	Ser Thr phosphatase family protein	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
YHH1_k127_9548073_0	290397.Adeh_3107	5.498e-61	233.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria	1224|Proteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
YHH1_k127_9548458_3	518766.Rmar_1855	7.491e-33	133.0	COG2143@1|root,COG2143@2|Bacteria,4PJYX@976|Bacteroidetes,1FK94@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
YHH1_k127_9548458_1	309807.SRU_2700	9.437e-84	296.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1FJ3E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
YHH1_k127_9548458_4	1123325.JHUV01000009_gene379	3.53e-26	115.0	COG1324@1|root,COG1324@2|Bacteria,2G58A@200783|Aquificae	200783|Aquificae	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
YHH1_k127_9548458_0	518766.Rmar_0452	1.121e-106	356.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1FJ0J@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Cellulose biosynthesis protein BcsQ	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YHH1_k127_9548458_2	880073.Calab_0242	4.299e-81	280.0	COG1475@1|root,COG1475@2|Bacteria,2NP7S@2323|unclassified Bacteria	2|Bacteria	K	Belongs to the ParB family	noc	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YHH1_k127_9550705_0	644966.Tmar_0077	1.932e-104	351.0	COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WCIN@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH1_k127_9550705_3	1089550.ATTH01000001_gene2434	6.053e-27	113.0	COG1539@1|root,COG1539@2|Bacteria,4PK5G@976|Bacteroidetes,1FJF0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
YHH1_k127_9550705_2	696281.Desru_0234	8.987e-36	143.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,2629P@186807|Peptococcaceae	186801|Clostridia	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
YHH1_k127_9550705_1	945713.IALB_2375	7.994e-73	253.0	COG1428@1|root,COG1428@2|Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
YHH1_k127_9550705_4	1191523.MROS_0141	2.685e-10	64.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	waaC	-	-	ko:K02841,ko:K02843,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH1_k127_9577741_1	1185653.A1A1_11337	1.736e-19	94.0	COG0300@1|root,COG0300@2|Bacteria,1UG37@1239|Firmicutes,4HC7Y@91061|Bacilli,26D5D@186818|Planococcaceae	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	fabG	-	1.1.1.100	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
YHH1_k127_9577741_0	706587.Desti_4935	9.397e-113	377.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_9586198_0	234267.Acid_7523	6.122e-24	115.0	COG0612@1|root,COG0612@2|Bacteria,3Y322@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_9620198_0	1121413.JMKT01000011_gene2381	5.16e-45	167.0	COG4284@1|root,COG4284@2|Bacteria,1Q5YI@1224|Proteobacteria,42QK5@68525|delta/epsilon subdivisions,2WKKW@28221|Deltaproteobacteria,2M92E@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM UTP--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
YHH1_k127_9620198_1	382464.ABSI01000012_gene2111	4.142e-32	136.0	COG2010@1|root,COG2010@2|Bacteria,46W25@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
YHH1_k127_9620198_2	443143.GM18_1267	2.072e-30	124.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
YHH1_k127_9620198_3	215803.DB30_0531	8.293e-19	97.0	COG0671@1|root,COG0671@2|Bacteria,1NDCB@1224|Proteobacteria,42W6H@68525|delta/epsilon subdivisions,2WREU@28221|Deltaproteobacteria,2YXPD@29|Myxococcales	28221|Deltaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
YHH1_k127_9631065_1	945713.IALB_1842	7.746e-23	100.0	COG2127@1|root,COG2127@2|Bacteria	2|Bacteria	T	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
YHH1_k127_9631065_0	945713.IALB_0035	1.896e-235	740.0	COG0013@1|root,COG0013@2|Bacteria	2|Bacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YHH1_k127_9634396_5	1191523.MROS_1684	2.214e-56	202.0	COG0102@1|root,COG0102@2|Bacteria	2|Bacteria	J	mRNA binding	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YHH1_k127_9634396_6	945713.IALB_0697	1.653e-39	150.0	COG0103@1|root,COG0103@2|Bacteria	2|Bacteria	J	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
YHH1_k127_9634396_2	945713.IALB_0698	1.45e-104	345.0	COG0052@1|root,COG0052@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YHH1_k127_9634396_4	709991.Odosp_2696	5.689e-68	240.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,22W7D@171551|Porphyromonadaceae	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
YHH1_k127_9634396_1	1191523.MROS_1688	8.563e-106	348.0	COG0528@1|root,COG0528@2|Bacteria	2|Bacteria	F	UMP kinase activity	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06240	AA_kinase
YHH1_k127_9634396_3	1191523.MROS_1689	2.238e-72	248.0	COG0233@1|root,COG0233@2|Bacteria	2|Bacteria	J	cytoplasmic translational termination	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
YHH1_k127_9634396_0	945713.IALB_1465	2.599e-128	416.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
YHH1_k127_963563_2	517418.Ctha_0432	1.38e-95	322.0	COG0438@1|root,COG0438@2|Bacteria,1FDVR@1090|Chlorobi	1090|Chlorobi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_963563_0	1519464.HY22_06390	1.227e-135	441.0	COG0859@1|root,COG0859@2|Bacteria,1FF11@1090|Chlorobi	1090|Chlorobi	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH1_k127_963563_1	945713.IALB_2891	3.063e-116	382.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
YHH1_k127_9637672_0	665571.STHERM_c02830	2.191e-116	379.0	COG0174@1|root,COG0174@2|Bacteria,2J6JS@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YHH1_k127_9637672_1	889378.Spiaf_0306	1.165e-33	134.0	COG1391@1|root,COG1391@2|Bacteria	2|Bacteria	H	[glutamate-ammonia-ligase] adenylyltransferase activity	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
YHH1_k127_9648353_0	517418.Ctha_0446	2.709e-186	604.0	COG0366@1|root,COG0366@2|Bacteria,1FD8X@1090|Chlorobi	1090|Chlorobi	G	PFAM alpha amylase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,hDGE_amylase
YHH1_k127_9658396_1	1499967.BAYZ01000019_gene6322	1.544e-105	349.0	COG0501@1|root,COG0501@2|Bacteria,2NP9X@2323|unclassified Bacteria	2|Bacteria	O	CAAX prenyl protease N-terminal, five membrane helices	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
YHH1_k127_9658396_0	517418.Ctha_1320	1.242e-162	523.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_9658396_2	1232410.KI421416_gene2699	6.376e-55	196.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2WJJP@28221|Deltaproteobacteria,43UUZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sulfate permease family	ychM	-	4.2.1.1	ko:K01673,ko:K03321	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.A.53.3	-	-	Pro_CA,STAS,STAS_2,Sulfate_transp
YHH1_k127_9660527_2	880073.Calab_0082	4.086e-31	127.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_9660527_1	493475.GARC_4186	9.949e-38	144.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria,467E8@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
YHH1_k127_9660527_0	945713.IALB_2380	6.466e-81	276.0	COG0496@1|root,COG0496@2|Bacteria	2|Bacteria	P	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
YHH1_k127_9664172_0	926550.CLDAP_29660	2.09e-132	432.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
YHH1_k127_9664172_1	1162668.LFE_0393	2.01e-24	112.0	COG4447@1|root,COG4447@2|Bacteria,3J16A@40117|Nitrospirae	40117|Nitrospirae	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YHH1_k127_9679892_0	926562.Oweho_1798	1.216e-111	387.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HY32@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	2.7.13.3	ko:K20971,ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y
YHH1_k127_9680389_4	697303.Thewi_0879	3.075e-32	128.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,42FCC@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
YHH1_k127_9680389_1	164328.Phyra85677	1.808e-61	221.0	COG1606@1|root,2RYIH@2759|Eukaryota,3QA39@4776|Peronosporales	4776|Peronosporales	L	tRNA processing	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9680389_2	391037.Sare_2200	1.688e-52	198.0	COG2040@1|root,COG2040@2|Bacteria,2GIWK@201174|Actinobacteria,4DIG6@85008|Micromonosporales	201174|Actinobacteria	E	Homocysteine S-methyltransferase	mmuM	-	2.1.1.10	ko:K00547,ko:K21169	ko00270,ko01059,ko01100,ko01110,ko01130,map00270,map01059,map01100,map01110,map01130	M00825	R00650	RC00003,RC00035	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
YHH1_k127_9680389_3	1042877.GQS_10515	5.313e-42	175.0	COG1800@1|root,arCOG07561@1|root,arCOG02164@2157|Archaea,arCOG07561@2157|Archaea,2XV3J@28890|Euryarchaeota,2435K@183968|Thermococci	183968|Thermococci	K	Transglutaminase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF553
YHH1_k127_9680389_0	1519464.HY22_08830	1.828e-72	274.0	COG0642@1|root,COG2208@1|root,COG2205@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
YHH1_k127_9680389_6	1304885.AUEY01000078_gene1048	1.799e-06	60.0	COG1462@1|root,COG1462@2|Bacteria,1R8Z9@1224|Proteobacteria,42XNA@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
YHH1_k127_9680389_5	518766.Rmar_0973	6.009e-11	75.0	COG1523@1|root,COG1523@2|Bacteria	2|Bacteria	G	belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	PUD,YSIRK_signal
YHH1_k127_9709371_0	1379698.RBG1_1C00001G1482	9.561e-134	449.0	COG1193@1|root,COG1193@2|Bacteria,2NNS1@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
YHH1_k127_9709371_1	1173028.ANKO01000247_gene3954	1.137e-21	96.0	2E46S@1|root,32Z2Q@2|Bacteria,1GA29@1117|Cyanobacteria,1HHD8@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9744643_0	945713.IALB_1644	0.0	1076.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH1_k127_9754869_1	1209989.TepiRe1_1994	4.119e-07	54.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
YHH1_k127_9754869_0	429009.Adeg_1981	5.666e-54	196.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,42GDH@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
YHH1_k127_9754869_2	518766.Rmar_0524	5.548e-06	59.0	COG1785@1|root,COG3656@1|root,COG1785@2|Bacteria,COG3656@2|Bacteria,4NG3D@976|Bacteroidetes,1FIWB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
YHH1_k127_9760132_1	319225.Plut_0919	3.37e-109	374.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1FD6C@1090|Chlorobi	1090|Chlorobi	P	PFAM CBS domain containing protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
YHH1_k127_9760132_4	698769.JFBD01000005_gene2929	9.714e-06	56.0	COG4758@1|root,COG4758@2|Bacteria,1VE20@1239|Firmicutes	1239|Firmicutes	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
YHH1_k127_9760132_2	1191523.MROS_1664	1.307e-91	308.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	VPA0557	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
YHH1_k127_9760132_0	1191523.MROS_1665	3.467e-110	370.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	VPA0558	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
YHH1_k127_9760132_3	1191523.MROS_1666	1.72e-70	248.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	VPA0559	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
YHH1_k127_9760340_0	204669.Acid345_3357	2.631e-25	122.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
YHH1_k127_9762945_3	1123278.KB893388_gene5776	1.245e-17	85.0	COG2318@1|root,COG2318@2|Bacteria,4NNQA@976|Bacteroidetes,47Q00@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH1_k127_9762945_1	371042.NG99_08040	8.031e-55	202.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
YHH1_k127_9762945_0	1304885.AUEY01000007_gene1357	4.988e-115	395.0	COG2202@1|root,COG2905@1|root,COG4564@1|root,COG2202@2|Bacteria,COG2905@2|Bacteria,COG4564@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2WJF5@28221|Deltaproteobacteria,2MIA9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,PAS_8,cNMP_binding,sCache_2
YHH1_k127_9812858_1	1519464.HY22_11180	2.141e-74	255.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
YHH1_k127_9812858_4	936455.KI421499_gene7374	5.402e-12	77.0	COG3391@1|root,COG4625@1|root,COG3391@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,3JUBZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PAP2,PATR
YHH1_k127_9812858_0	880073.Calab_1657	1.587e-77	274.0	COG1408@1|root,COG1408@2|Bacteria,2NRFJ@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
YHH1_k127_9812858_3	756272.Plabr_0410	2.238e-44	171.0	COG5587@1|root,COG5587@2|Bacteria,2J2RK@203682|Planctomycetes	203682|Planctomycetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
YHH1_k127_9812858_2	264462.Bd1731	8.737e-63	226.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,42T7R@68525|delta/epsilon subdivisions,2MTV6@213481|Bdellovibrionales,2WNQ2@28221|Deltaproteobacteria	213481|Bdellovibrionales	DJ	family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
YHH1_k127_9814427_0	1168034.FH5T_17590	3.599e-133	443.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,2G2QE@200643|Bacteroidia	976|Bacteroidetes	O	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
YHH1_k127_9814427_1	945713.IALB_1883	5.433e-126	424.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
YHH1_k127_9814427_2	313606.M23134_05658	8.452e-55	199.0	COG1842@1|root,COG1842@2|Bacteria,4NFSJ@976|Bacteroidetes,47PG9@768503|Cytophagia	976|Bacteroidetes	KT	Phage shock protein A (IM30) suppresses sigma54-dependent transcription	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
YHH1_k127_9814427_3	313612.L8106_17009	2.649e-21	99.0	2DBZS@1|root,2ZC3A@2|Bacteria,1G58M@1117|Cyanobacteria,1HARD@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
YHH1_k127_9820378_0	324925.Ppha_1259	6.013e-55	205.0	COG1512@1|root,COG1512@2|Bacteria,1FENY@1090|Chlorobi	1090|Chlorobi	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
YHH1_k127_9820378_1	1237149.C900_03153	1.945e-54	199.0	COG3762@1|root,COG3762@2|Bacteria	2|Bacteria	S	Membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
YHH1_k127_9830434_0	1210884.HG799466_gene12962	7.973e-71	252.0	COG1961@1|root,COG1961@2|Bacteria,2IYJH@203682|Planctomycetes	203682|Planctomycetes	L	Site-specific recombinase, DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH1_k127_9831966_1	517418.Ctha_1263	1.011e-43	162.0	COG1595@1|root,COG1595@2|Bacteria,1FDU7@1090|Chlorobi	1090|Chlorobi	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_9831966_2	717231.Flexsi_0097	2.306e-20	98.0	COG0589@1|root,COG0589@2|Bacteria,2GFI3@200930|Deferribacteres	200930|Deferribacteres	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YHH1_k127_9831966_0	391625.PPSIR1_41839	4.534e-85	288.0	COG0823@1|root,COG0823@2|Bacteria,1QW3I@1224|Proteobacteria,42YA5@68525|delta/epsilon subdivisions,2WU6I@28221|Deltaproteobacteria,2Z3J0@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH1_k127_9841013_3	1519464.HY22_02940	9.79e-13	77.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PQQ_2,TPR_8
YHH1_k127_9841013_2	1519464.HY22_01020	5.256e-24	118.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
YHH1_k127_9841013_1	945713.IALB_3095	5.288e-66	232.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
YHH1_k127_9841013_0	1191523.MROS_1831	4.197e-109	362.0	COG0240@1|root,COG0240@2|Bacteria	2|Bacteria	I	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
YHH1_k127_9852287_1	639030.JHVA01000001_gene971	3.995e-16	83.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_9852287_2	479432.Sros_3998	5.36e-16	83.0	COG2197@1|root,COG2197@2|Bacteria,2IFGE@201174|Actinobacteria,4EFN4@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_9852287_0	153721.MYP_2602	7.23e-80	289.0	COG1572@1|root,COG2931@1|root,COG3227@1|root,COG3266@1|root,COG3291@1|root,COG4447@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
YHH1_k127_9853913_1	945713.IALB_0461	3.323e-21	100.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH1_k127_9853913_0	1120968.AUBX01000009_gene282	1.997e-172	548.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,47M06@768503|Cytophagia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
YHH1_k127_9853913_2	1191523.MROS_2261	0.0002962	43.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	vorD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_21,Fer4_4,Fer4_7
YHH1_k127_9862918_1	1121456.ATVA01000002_gene3203	6.697e-116	390.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH1_k127_9862918_0	1191523.MROS_1385	1.383e-246	785.0	COG1067@1|root,COG1067@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	ycbZ	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
YHH1_k127_9863417_1	944547.ABLL_0883	6.95e-86	290.0	COG2253@1|root,COG2253@2|Bacteria,1PZRM@1224|Proteobacteria,42SAJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH1_k127_9863417_2	338963.Pcar_0280	1.289e-75	259.0	COG5340@1|root,COG5340@2|Bacteria,1R1GM@1224|Proteobacteria,42WEF@68525|delta/epsilon subdivisions,2WTDA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9863417_3	595537.Varpa_1713	3.53e-53	191.0	COG4898@1|root,COG4898@2|Bacteria,1RHGW@1224|Proteobacteria,2W2HP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
YHH1_k127_9863417_0	748247.AZKH_3336	1.131e-87	292.0	COG0262@1|root,COG0262@2|Bacteria,1R6X0@1224|Proteobacteria,2VI26@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
YHH1_k127_9863417_5	525897.Dbac_0823	3.924e-22	98.0	COG2026@1|root,COG2026@2|Bacteria,1N80B@1224|Proteobacteria,437Y0@68525|delta/epsilon subdivisions,2WRY3@28221|Deltaproteobacteria,2MDXE@213115|Desulfovibrionales	28221|Deltaproteobacteria	DJ	PFAM plasmid	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
YHH1_k127_9863417_6	909663.KI867150_gene229	2.387e-19	92.0	2E9PU@1|root,333W6@2|Bacteria,1N6VC@1224|Proteobacteria,42WJ7@68525|delta/epsilon subdivisions,2WRB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9863417_4	1207063.P24_01130	1.19e-34	135.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2TRPD@28211|Alphaproteobacteria,2JRS3@204441|Rhodospirillales	204441|Rhodospirillales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
YHH1_k127_9865675_2	945713.IALB_2300	6.197e-54	213.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
YHH1_k127_9865675_0	880073.Calab_1103	4.871e-66	238.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
YHH1_k127_9865675_1	945713.IALB_1165	1.412e-62	228.0	COG5009@1|root,COG5009@2|Bacteria	2|Bacteria	M	serine-type D-Ala-D-Ala carboxypeptidase activity	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
YHH1_k127_9870164_2	378806.STAUR_5358	4.4e-06	55.0	COG1729@1|root,COG1729@2|Bacteria,1N780@1224|Proteobacteria,42V4V@68525|delta/epsilon subdivisions,2WR6U@28221|Deltaproteobacteria,2YW0N@29|Myxococcales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9870164_0	1519464.HY22_11920	3.698e-32	141.0	COG3391@1|root,COG4412@1|root,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	CARDB,FTP,He_PIG,NHL,PA,Peptidase_M30,Peptidase_M36,Peptidase_M6
YHH1_k127_9870164_1	1519464.HY22_13130	1.25e-21	106.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH1_k127_9870527_2	1116472.MGMO_8c00880	8.287e-09	57.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,1XFHT@135618|Methylococcales	135618|Methylococcales	M	PFAM N-acetylneuraminic acid synthase, N-terminal	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
YHH1_k127_9870527_1	517418.Ctha_2573	3.171e-91	306.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
YHH1_k127_9870527_0	313606.M23134_05475	0.0	1123.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
YHH1_k127_987149_11	880073.Calab_2923	1.498e-20	105.0	290EY@1|root,2ZN47@2|Bacteria,2NRVY@2323|unclassified Bacteria	880073.Calab_2923|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_987149_5	1336235.JAEG01000006_gene665	1.772e-52	197.0	COG1409@1|root,COG1409@2|Bacteria,1NXRI@1224|Proteobacteria,2U1WZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.3.2	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
YHH1_k127_987149_0	316274.Haur_3185	1.08e-206	653.0	COG1233@1|root,COG1233@2|Bacteria,2G5ZA@200795|Chloroflexi,375CK@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM amine oxidase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
YHH1_k127_987149_3	999541.bgla_1g26390	1.755e-84	293.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,2WFU5@28216|Betaproteobacteria,1KI63@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
YHH1_k127_987149_7	247490.KSU1_D0399	1.661e-43	167.0	COG2095@1|root,COG2095@2|Bacteria,2J0YY@203682|Planctomycetes	203682|Planctomycetes	U	MarC family integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	MarC
YHH1_k127_987149_8	290315.Clim_2197	2.499e-40	158.0	COG0218@1|root,COG0218@2|Bacteria,1FDYH@1090|Chlorobi	1090|Chlorobi	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
YHH1_k127_987149_9	518766.Rmar_0870	1.56e-35	143.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1FJBK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
YHH1_k127_987149_1	945713.IALB_0939	1.678e-125	410.0	COG0202@1|root,COG0202@2|Bacteria	2|Bacteria	K	RNA polymerase activity	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YHH1_k127_987149_4	1191523.MROS_0191	2.482e-62	216.0	COG0100@1|root,COG0100@2|Bacteria	2|Bacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YHH1_k127_987149_6	999413.HMPREF1094_01748	2.192e-47	173.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,3VQQU@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YHH1_k127_987149_12	1121267.JHZL01000006_gene949	1.456e-15	76.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2YQQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
YHH1_k127_987149_10	945713.IALB_0934	9.555e-34	133.0	COG0361@1|root,COG0361@2|Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
YHH1_k127_987149_2	645991.Sgly_0413	2.632e-90	304.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,260SK@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH1_k127_987149_13	1191523.MROS_0196	7.535e-13	68.0	COG0201@1|root,COG0201@2|Bacteria	2|Bacteria	U	protein transport	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YHH1_k127_9893305_1	742738.HMPREF9460_02280	1.258e-60	220.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,24850@186801|Clostridia,267PT@186813|unclassified Clostridiales	186801|Clostridia	F	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
YHH1_k127_9893305_0	518766.Rmar_0603	3.453e-120	406.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1FJJN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YHH1_k127_9915792_1	1054213.HMPREF9946_04899	1.032e-10	71.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria	1224|Proteobacteria	MU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
YHH1_k127_9915792_0	1304875.JAFZ01000002_gene300	1.498e-99	333.0	COG2855@1|root,COG2855@2|Bacteria,3TA2V@508458|Synergistetes	508458|Synergistetes	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
YHH1_k127_9927897_1	1121430.JMLG01000021_gene1384	2.042e-27	121.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia,262DJ@186807|Peptococcaceae	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
YHH1_k127_9927897_2	983548.Krodi_0989	1.051e-25	124.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1HWRP@117743|Flavobacteriia,37DWG@326319|Dokdonia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
YHH1_k127_9927897_0	518766.Rmar_1964	1.963e-74	262.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1FJ5E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9931808_0	572477.Alvin_2695	4.033e-07	64.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1WVYS@135613|Chromatiales	135613|Chromatiales	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
YHH1_k127_9957543_0	1191523.MROS_1743	2.424e-120	398.0	COG0272@1|root,COG0272@2|Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972,ko:K10754	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	M00289,M00295	R00382	RC00005	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YHH1_k127_9957543_1	500635.MITSMUL_05295	6.34e-08	59.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4H4XS@909932|Negativicutes	909932|Negativicutes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
YHH1_k127_9962583_2	1185876.BN8_03106	3.296e-22	99.0	2DPSP@1|root,33387@2|Bacteria,4NVSW@976|Bacteroidetes,47T2S@768503|Cytophagia	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YHH1_k127_9962583_0	589924.Ferp_1932	1.119e-60	224.0	COG0477@1|root,arCOG00130@2157|Archaea,2XSTP@28890|Euryarchaeota	28890|Euryarchaeota	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH1_k127_9962583_1	485918.Cpin_3235	3.745e-25	110.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1INW1@117747|Sphingobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
YHH1_k127_9963578_0	518766.Rmar_1427	3.02e-203	642.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1FIMS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YHH1_k127_9991303_2	1123393.KB891316_gene1806	7.973e-08	53.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,1KSVR@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
YHH1_k127_9991303_0	1123393.KB891316_gene1807	4.049e-164	521.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,1KS77@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Coproporphyrinogen III oxidase	-	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
YHH1_k127_9991303_1	1227500.C494_05698	3.047e-10	66.0	COG0517@1|root,arCOG00606@2157|Archaea	2157|Archaea	I	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
## 2403 queries scanned
## Total time (seconds): 7.3690338134765625
## Rate: 326.09 q/s