## Wed Dec 17 03:40:46 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/YHH1_bin.50.fa -m mmseqs --itype genome -o YHH1_bin.50 --output_dir /data/result/bins/wyx/egg/YHH1_bin.50 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YHH1_k127_10044857_0	324602.Caur_1075	1.125e-116	387.0	COG1472@1|root,COG1472@2|Bacteria,2G7NE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
YHH1_k127_10075478_0	439481.Aboo_0791	2.941e-93	316.0	COG0504@1|root,arCOG00063@2157|Archaea,2XTR2@28890|Euryarchaeota,3F2HU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
YHH1_k127_10119622_0	237368.SCABRO_00441	3.529e-81	278.0	COG1236@1|root,COG1236@2|Bacteria,2IXNS@203682|Planctomycetes	203682|Planctomycetes	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
YHH1_k127_10119622_1	883156.HMPREF9282_01722	1.897e-41	162.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4H31R@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
YHH1_k127_1012258_0	1120963.KB894504_gene1882	8.543e-06	58.0	COG1664@1|root,COG2931@1|root,COG5571@1|root,COG1664@2|Bacteria,COG2931@2|Bacteria,COG5571@2|Bacteria,1QUZJ@1224|Proteobacteria,1T318@1236|Gammaproteobacteria,2Q1VF@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	MN	calcium- and calmodulin-responsive adenylate cyclase activity	mshQ	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Bactofilin,H_lectin,Laminin_G_3,PA14
YHH1_k127_10133461_0	449447.MAE_07630	9.509e-19	93.0	COG1569@1|root,COG1569@2|Bacteria,1G9IG@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH1_k127_10133461_1	309801.trd_0965	3.406e-10	62.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia	189775|Thermomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YHH1_k127_10169029_2	1384054.N790_03310	3.768e-11	68.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1X7HR@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
YHH1_k127_10169029_1	292459.STH3074	2.781e-38	153.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YHH1_k127_10169029_0	357808.RoseRS_1185	6.573e-40	159.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi,375C3@32061|Chloroflexia	32061|Chloroflexia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
YHH1_k127_10169029_3	1499680.CCFE01000021_gene2229	0.000127	51.0	COG1570@1|root,COG1570@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
YHH1_k127_10195497_0	1123368.AUIS01000006_gene572	5.513e-66	232.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1RSBH@1236|Gammaproteobacteria,2NCEE@225057|Acidithiobacillales	225057|Acidithiobacillales	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
YHH1_k127_10213762_1	317936.Nos7107_2597	1.319e-14	81.0	COG0563@1|root,COG0563@2|Bacteria,1G50C@1117|Cyanobacteria,1HIMN@1161|Nostocales	1117|Cyanobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.adk	ADK
YHH1_k127_10213762_0	747365.Thena_0524	3.271e-26	113.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,42F6V@68295|Thermoanaerobacterales	186801|Clostridia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH1_k127_10224597_1	1385935.N836_10645	1.893e-72	251.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1G0GP@1117|Cyanobacteria,1H9GG@1150|Oscillatoriales	1117|Cyanobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH1_k127_10224597_0	485914.Hmuk_3413	1.543e-72	261.0	COG2379@1|root,arCOG04170@2157|Archaea,2XSTZ@28890|Euryarchaeota,23SY7@183963|Halobacteria	183963|Halobacteria	G	Hydroxypyruvate reductase	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
YHH1_k127_10224597_3	1336243.JAEA01000014_gene3653	1.071e-38	149.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2U05I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
YHH1_k127_10224597_2	688270.Celal_0206	1.665e-53	199.0	COG1187@1|root,COG1187@2|Bacteria,4NFE1@976|Bacteroidetes,1HY0B@117743|Flavobacteriia,1F8QF@104264|Cellulophaga	976|Bacteroidetes	J	COGs COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH1_k127_10266287_1	1185876.BN8_05885	2.394e-64	230.0	COG1004@1|root,COG1004@2|Bacteria	2|Bacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH1_k127_10266287_0	331113.SNE_A17470	7.057e-86	297.0	COG0391@1|root,COG0391@2|Bacteria	2|Bacteria	S	phosphotransferase activity, for other substituted phosphate groups	ybhK	-	-	-	-	-	-	-	-	-	-	-	UPF0052
YHH1_k127_10303964_0	1356854.N007_11825	5.138e-84	290.0	COG3387@1|root,COG3387@2|Bacteria,1V0CI@1239|Firmicutes,4HCZU@91061|Bacilli	91061|Bacilli	G	Glycosyl hydrolases family 15	-	-	-	ko:K07190	ko04020,ko04910,ko04922,map04020,map04910,map04922	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_15
YHH1_k127_10303964_2	869210.Marky_0026	1.624e-19	93.0	COG0071@1|root,COG0071@2|Bacteria,1WJU3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YHH1_k127_10303964_1	1237149.C900_02490	3.139e-30	133.0	2C578@1|root,32RF7@2|Bacteria,4NS0I@976|Bacteroidetes	976|Bacteroidetes	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Gmad2
YHH1_k127_10332102_1	1206725.BAFU01000182_gene2263	1.185e-06	57.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4G51W@85025|Nocardiaceae	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,HTH_38,rve
YHH1_k127_10332102_0	935948.KE386495_gene1937	2.722e-125	432.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,42FSC@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyltransferase 36 associated	ndvB	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glyco_hydro_36,Glyco_transf_36,Glycoamylase
YHH1_k127_10369098_0	403833.Pmob_0994	7.801e-67	238.0	COG0415@1|root,COG0415@2|Bacteria,2GDRQ@200918|Thermotogae	200918|Thermotogae	H	PFAM DNA photolyase FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
YHH1_k127_10395689_0	760142.Hipma_1451	1.01e-50	197.0	COG2801@1|root,COG2801@2|Bacteria,1R1RX@1224|Proteobacteria,433M4@68525|delta/epsilon subdivisions,2WXFK@28221|Deltaproteobacteria,2M7NM@213113|Desulfurellales	2|Bacteria	L	PFAM Bacterial regulatory protein, Fis family	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_28,HTH_32,HTH_8,rve,rve_3
YHH1_k127_10414132_0	1168034.FH5T_09120	2.815e-108	359.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,2FMM2@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
YHH1_k127_10426133_0	665956.HMPREF1032_01781	2.421e-49	180.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3WGTU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
YHH1_k127_10448381_0	420246.GTNG_1123	4.413e-174	571.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1WFAI@129337|Geobacillus	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YHH1_k127_10458222_0	1122130.AUHN01000008_gene1588	1.459e-115	395.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
YHH1_k127_10458222_3	148814.JI66_07680	1.644e-12	73.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,3F3Y0@33958|Lactobacillaceae	91061|Bacilli	K	response regulator	vanR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_10458222_1	1122138.AQUZ01000044_gene4534	8.272e-93	317.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4DQ20@85009|Propionibacteriales	201174|Actinobacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH1_k127_10458222_2	373903.Hore_05990	3.329e-69	250.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,3WAFC@53433|Halanaerobiales	186801|Clostridia	U	PFAM Bacterial type II secretion system protein F domain	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH1_k127_10458222_4	937777.Deipe_1975	1.748e-05	50.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	gsp	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,Pilin_GH
YHH1_k127_10468113_0	1218084.BBJK01000104_gene6532	5.96e-35	143.0	COG2319@1|root,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria,1K773@119060|Burkholderiaceae	28216|Betaproteobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,TIR_2,WD40
YHH1_k127_10499456_0	1047013.AQSP01000118_gene1252	8.291e-27	124.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10499721_0	1392838.AWNM01000009_gene2723	2.491e-08	64.0	COG1378@1|root,COG1378@2|Bacteria,1PZ3N@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_10548809_1	643867.Ftrac_2073	9.11e-29	120.0	COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,47P1Y@768503|Cytophagia	976|Bacteroidetes	K	PFAM ATP cone domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
YHH1_k127_10548809_0	742726.HMPREF9448_00377	2.351e-29	122.0	COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,2G370@200643|Bacteroidia,22Y5I@171551|Porphyromonadaceae	976|Bacteroidetes	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
YHH1_k127_1055331_0	330214.NIDE3501	2.4e-36	149.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
YHH1_k127_10587089_0	880072.Desac_0814	4.674e-40	164.0	COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,43DC6@68525|delta/epsilon subdivisions,2X8I6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10587089_1	525904.Tter_2558	1.739e-34	139.0	COG1814@1|root,COG1814@2|Bacteria,2NRID@2323|unclassified Bacteria	2|Bacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
YHH1_k127_10599652_1	748449.Halha_1774	1.054e-43	175.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WAHA@53433|Halanaerobiales	186801|Clostridia	M	Penicillin-binding protein dimerisation domain	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
YHH1_k127_10599652_0	684949.ATTJ01000001_gene665	2.342e-66	237.0	COG0275@1|root,COG0275@2|Bacteria,1WJ5G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
YHH1_k127_10599652_2	555088.DealDRAFT_1355	1.648e-40	155.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,42JX7@68298|Syntrophomonadaceae	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
YHH1_k127_10599652_3	292459.STH429	2.55e-19	90.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
YHH1_k127_10670198_1	1313265.JNIE01000008_gene89	5.978e-65	236.0	COG0793@1|root,COG0793@2|Bacteria,2G3RT@200783|Aquificae	200783|Aquificae	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
YHH1_k127_10670198_2	419665.Maeo_0003	1.582e-16	91.0	COG0598@1|root,arCOG02265@2157|Archaea,2XTRP@28890|Euryarchaeota,23QMB@183939|Methanococci	183939|Methanococci	P	Mediates influx of magnesium ions	corA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YHH1_k127_10670198_0	515635.Dtur_1693	1.347e-134	444.0	COG0215@1|root,COG0215@2|Bacteria	2|Bacteria	J	cysteine-tRNA ligase activity	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
YHH1_k127_10691441_0	926690.KE386573_gene822	0.0008889	52.0	COG1404@1|root,arCOG03439@1|root,arCOG00702@2157|Archaea,arCOG03439@2157|Archaea,2XSZR@28890|Euryarchaeota,23U34@183963|Halobacteria	183963|Halobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
YHH1_k127_10693636_1	1132855.KB913035_gene2036	1.249e-31	131.0	28IX1@1|root,2ZC5T@2|Bacteria,1R35E@1224|Proteobacteria,2VQUH@28216|Betaproteobacteria,2KKKU@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
YHH1_k127_10693636_0	1511.CLOST_1149	1.918e-61	231.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,25QY6@186804|Peptostreptococcaceae	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YHH1_k127_10736167_0	1218108.KB908301_gene2386	1.878e-78	272.0	COG0507@1|root,COG0640@1|root,COG0507@2|Bacteria,COG0640@2|Bacteria,4NF6J@976|Bacteroidetes,1HZ14@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	HRDC,HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
YHH1_k127_10736167_1	1280390.CBQR020000100_gene2271	1.077e-19	93.0	COG4818@1|root,COG4818@2|Bacteria,1VG59@1239|Firmicutes,4HP4V@91061|Bacilli,26ZHT@186822|Paenibacillaceae	91061|Bacilli	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10750624_0	637905.SVI_3253	1.229e-101	337.0	COG0167@1|root,COG0167@2|Bacteria,1QC2A@1224|Proteobacteria,1T7Q8@1236|Gammaproteobacteria,2QDCB@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YHH1_k127_10750624_1	1125712.HMPREF1316_1365	1.43e-05	51.0	COG1432@1|root,COG1432@2|Bacteria,2HVW0@201174|Actinobacteria,4CXKZ@84998|Coriobacteriia	84998|Coriobacteriia	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
YHH1_k127_10751218_0	228410.NE1051	2.04e-92	316.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,372D7@32003|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YHH1_k127_10835027_0	370438.PTH_0703	1e-13	74.0	COG5611@1|root,COG5611@2|Bacteria,1V8UV@1239|Firmicutes,24KGR@186801|Clostridia	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH1_k127_10842310_0	1195236.CTER_0098	6.68e-29	132.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WH2S@541000|Ruminococcaceae	186801|Clostridia	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
YHH1_k127_10873005_0	1121918.ARWE01000001_gene1408	1.137e-33	142.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria	1224|Proteobacteria	L	IS30 family	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
YHH1_k127_10916714_2	1219084.AP014508_gene1107	2.59e-19	92.0	COG1155@1|root,COG1155@2|Bacteria,2GDY9@200918|Thermotogae	200918|Thermotogae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
YHH1_k127_10916714_0	941824.TCEL_00593	3.442e-196	621.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,36DRP@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH1_k127_10916714_1	1120998.AUFC01000008_gene1080	3.651e-43	166.0	COG1394@1|root,COG1394@2|Bacteria,1TQ1Y@1239|Firmicutes,247TC@186801|Clostridia,3WDBN@538999|Clostridiales incertae sedis	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
YHH1_k127_10916714_3	667014.Thein_1585	4.379e-18	88.0	COG0758@1|root,COG0758@2|Bacteria,2GHI2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
YHH1_k127_10959684_0	525904.Tter_1074	8.862e-158	516.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YHH1_k127_10962086_0	526222.Desal_1305	3.045e-61	215.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2M9J9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
YHH1_k127_10962086_1	1122609.AUGT01000012_gene4458	3.482e-37	146.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4DQW7@85009|Propionibacteriales	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
YHH1_k127_10962086_2	926569.ANT_01690	9.165e-23	103.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
YHH1_k127_10994068_0	388051.AUFE01000166_gene71	1.394e-103	344.0	COG4467@1|root,COG4467@2|Bacteria,1PPMF@1224|Proteobacteria,2VMNS@28216|Betaproteobacteria,1KE34@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Involved in initiation control of chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
YHH1_k127_1101709_0	130081.XP_005704249.1	1.901e-54	196.0	COG0612@1|root,KOG0960@2759|Eukaryota	2759|Eukaryota	P	mitochondrial electron transport, ubiquinol to cytochrome c	MAS1	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005759,GO:0006091,GO:0006119,GO:0006122,GO:0006139,GO:0006163,GO:0006508,GO:0006605,GO:0006626,GO:0006627,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0008104,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016485,GO:0016787,GO:0017087,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0023052,GO:0031090,GO:0031930,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031982,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034982,GO:0042773,GO:0042775,GO:0042886,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045184,GO:0045275,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046907,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0065007,GO:0070011,GO:0070013,GO:0070069,GO:0070469,GO:0070585,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072521,GO:0072594,GO:0072655,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0140096,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	3.4.24.64	ko:K01412,ko:K07263,ko:K17732	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_1101709_1	269799.Gmet_0815	8.049e-05	53.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria,43SP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SurA N-terminal domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
YHH1_k127_1118260_0	411462.DORLON_00674	6.789e-05	49.0	COG1378@1|root,COG1378@2|Bacteria,1V2DD@1239|Firmicutes,24BVS@186801|Clostridia,27UUD@189330|Dorea	186801|Clostridia	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
YHH1_k127_116426_0	638302.HMPREF0908_0679	1.028e-38	152.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4H3YJ@909932|Negativicutes	909932|Negativicutes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH1_k127_116426_4	744985.HIMB59_00003060	0.0009201	45.0	COG0333@1|root,COG0333@2|Bacteria,1PU3Y@1224|Proteobacteria,2UF54@28211|Alphaproteobacteria,4BR11@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
YHH1_k127_116426_1	485913.Krac_8246	2.841e-27	123.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
YHH1_k127_116426_3	1341151.ASZU01000004_gene381	9.967e-10	69.0	COG1051@1|root,COG1051@2|Bacteria,1VAMK@1239|Firmicutes,4HKCB@91061|Bacilli,27C00@186824|Thermoactinomycetaceae	91061|Bacilli	F	NUDIX domain	apfA	-	3.6.1.61	ko:K18445	ko00230,map00230	-	R00184	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
YHH1_k127_116426_2	1235279.C772_00564	4.797e-24	105.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,26DF7@186818|Planococcaceae	91061|Bacilli	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YHH1_k127_1174636_0	929703.KE386491_gene1828	1.219e-29	136.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH1_k127_1180985_0	313595.P700755_002118	1.321e-47	184.0	COG0433@1|root,COG0784@1|root,COG0433@2|Bacteria,COG0784@2|Bacteria,4NU1B@976|Bacteroidetes,1I4WR@117743|Flavobacteriia	976|Bacteroidetes	T	TraM recognition site of TraD and TraG	-	-	-	-	-	-	-	-	-	-	-	-	TraG-D_C,TrwB_AAD_bind
YHH1_k127_1184845_0	926550.CLDAP_00560	1.434e-09	72.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
YHH1_k127_118659_0	118163.Ple7327_2004	2.026e-248	782.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1G0GP@1117|Cyanobacteria,3VIGN@52604|Pleurocapsales	1117|Cyanobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH1_k127_118659_1	404589.Anae109_2168	3.204e-153	495.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,2YWXC@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
YHH1_k127_120225_0	717785.HYPMC_2788	0.0001167	48.0	COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2UCNX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	PFAM Excinuclease ABC, C subunit domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH1_k127_1211807_0	283699.D172_2488	9.04e-40	160.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria,2Q2H3@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Integrase core domain	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
YHH1_k127_1229049_0	485913.Krac_10545	6.428e-55	200.0	COG0528@1|root,COG0528@2|Bacteria	2|Bacteria	F	UMP kinase activity	mosB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030151,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	2.7.4.22	ko:K00947,ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YHH1_k127_1229049_1	56107.Cylst_3464	0.0002801	46.0	COG3609@1|root,COG3609@2|Bacteria,1G98M@1117|Cyanobacteria,1HPZQ@1161|Nostocales	1117|Cyanobacteria	K	addiction module antidote protein, CC2985 family	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
YHH1_k127_1229320_0	717605.Theco_0203	1.497e-284	898.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,26SMJ@186822|Paenibacillaceae	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH1_k127_1229320_1	439292.Bsel_1085	1.531e-146	477.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,26NID@186821|Sporolactobacillaceae	91061|Bacilli	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH1_k127_1250888_2	196162.Noca_1124	0.0006424	50.0	2F3VC@1|root,33WMI@2|Bacteria,2H5AA@201174|Actinobacteria	201174|Actinobacteria	S	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH1_k127_1250888_1	743720.Psefu_3827	9.692e-09	64.0	COG4968@1|root,COG4968@2|Bacteria,1PSJF@1224|Proteobacteria,1RVXC@1236|Gammaproteobacteria,1YVNT@136845|Pseudomonas putida group	1236|Gammaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
YHH1_k127_1250888_0	1123373.ATXI01000010_gene1019	5.659e-09	65.0	COG1989@1|root,COG1989@2|Bacteria,2GGZR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
YHH1_k127_1293213_0	321327.CYA_1531	1.03e-12	80.0	COG0739@1|root,COG0739@2|Bacteria,1GGCW@1117|Cyanobacteria,1H2H9@1129|Synechococcus	1117|Cyanobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH1_k127_1293213_1	1121434.AULY01000011_gene1827	0.0003006	46.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH1_k127_1296267_2	351160.LRC75	5.564e-06	56.0	arCOG03430@1|root,arCOG03430@2157|Archaea	2157|Archaea	S	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
YHH1_k127_1296267_1	1120951.AUBG01000005_gene2114	1.651e-44	179.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_1296267_0	452637.Oter_4630	6.31e-94	318.0	COG0612@1|root,COG0612@2|Bacteria,46TRC@74201|Verrucomicrobia,3K94V@414999|Opitutae	414999|Opitutae	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH1_k127_1315496_0	1499967.BAYZ01000014_gene6405	1.47e-33	141.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,PP-binding,ketoacyl-synt
YHH1_k127_1327039_0	555079.Toce_1827	2.978e-83	286.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,42F5T@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM malic	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
YHH1_k127_1327039_1	1123368.AUIS01000007_gene2732	7.215e-36	144.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,1S0NW@1236|Gammaproteobacteria,2NBVS@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Iron/manganese superoxide dismutases, C-terminal domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C
YHH1_k127_1342043_0	479434.Sthe_1218	7.382e-40	167.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi,27XGY@189775|Thermomicrobia	189775|Thermomicrobia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YHH1_k127_1342043_1	1192034.CAP_0019	2.058e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,1Q2EC@1224|Proteobacteria,43804@68525|delta/epsilon subdivisions,2X3A2@28221|Deltaproteobacteria,2YV2B@29|Myxococcales	28221|Deltaproteobacteria	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
YHH1_k127_1359793_0	101162.XP_007693768.1	1.322e-15	85.0	2D0XG@1|root,2SFWP@2759|Eukaryota,3AEA0@33154|Opisthokonta,3P8RM@4751|Fungi	4751|Fungi	S	LAGLIDADG endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_1
YHH1_k127_1361174_0	742738.HMPREF9460_02550	5.178e-98	333.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,267P4@186813|unclassified Clostridiales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YHH1_k127_1419259_2	926550.CLDAP_38550	1.107e-10	67.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YHH1_k127_1419259_0	368407.Memar_1721	2.505e-68	242.0	COG1194@1|root,arCOG00462@2157|Archaea,2XSU9@28890|Euryarchaeota,2NBC3@224756|Methanomicrobia	224756|Methanomicrobia	L	PFAM HhH-GPD family protein	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YHH1_k127_1419259_1	1267535.KB906767_gene976	1.703e-66	234.0	COG0177@1|root,COG0177@2|Bacteria,3Y3QD@57723|Acidobacteria,2JI6M@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YHH1_k127_1420906_0	1122921.KB898202_gene3125	1.115e-111	369.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,26RSM@186822|Paenibacillaceae	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YHH1_k127_1420906_1	646529.Desaci_3491	1.044e-37	148.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,260QF@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
YHH1_k127_1420906_2	1408439.JHXW01000012_gene838	8.137e-30	125.0	COG0817@1|root,COG0817@2|Bacteria,37A4F@32066|Fusobacteria	32066|Fusobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
YHH1_k127_1431135_0	479434.Sthe_2499	1.702e-48	182.0	29JD5@1|root,306AN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1431135_1	56107.Cylst_3464	5.461e-07	53.0	COG3609@1|root,COG3609@2|Bacteria,1G98M@1117|Cyanobacteria,1HPZQ@1161|Nostocales	1117|Cyanobacteria	K	addiction module antidote protein, CC2985 family	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
YHH1_k127_1440700_0	290315.Clim_1499	2.677e-68	241.0	COG4912@1|root,COG4912@2|Bacteria,1FDUX@1090|Chlorobi	1090|Chlorobi	L	PFAM DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YHH1_k127_1450648_0	384765.SIAM614_02911	4.959e-08	61.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
YHH1_k127_145850_0	555088.DealDRAFT_1684	3.768e-30	133.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia	186801|Clostridia	C	Belongs to the V-ATPase 116 kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
YHH1_k127_1470692_0	1121104.AQXH01000002_gene660	3.786e-82	285.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1IQP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
YHH1_k127_1470692_1	314225.ELI_11630	0.0003688	44.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,2UCMQ@28211|Alphaproteobacteria,2K60M@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
YHH1_k127_1496345_0	1121423.JONT01000001_gene2024	2.918e-07	57.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,260A0@186807|Peptococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH1_k127_1496345_1	1121007.AUML01000034_gene1755	5.313e-07	61.0	COG1305@1|root,COG1305@2|Bacteria,4NZRT@976|Bacteroidetes,1I8DQ@117743|Flavobacteriia,2YGTM@290174|Aquimarina	976|Bacteroidetes	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_core
YHH1_k127_1503803_0	246194.CHY_1168	3.12e-77	271.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,42F5Q@68295|Thermoanaerobacterales	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
YHH1_k127_1518648_3	404589.Anae109_1916	2.762e-18	89.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,42TRE@68525|delta/epsilon subdivisions,2WQBH@28221|Deltaproteobacteria,2Z1JN@29|Myxococcales	28221|Deltaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
YHH1_k127_1518648_0	908338.HMPREF9286_0236	1.069e-51	190.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,22FYT@1570339|Peptoniphilaceae	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YHH1_k127_1518648_1	450851.PHZ_c1237	1.475e-40	154.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2U710@28211|Alphaproteobacteria,2KGAF@204458|Caulobacterales	204458|Caulobacterales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
YHH1_k127_1518648_2	1265505.ATUG01000001_gene3701	2.014e-19	91.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2WR6G@28221|Deltaproteobacteria,2MKWR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
YHH1_k127_1567202_2	204536.SULAZ_1633	2.025e-08	55.0	2B9ZZ@1|root,323DM@2|Bacteria	2|Bacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1567202_0	416591.Tlet_1936	3.31e-44	167.0	2DYKZ@1|root,34AAD@2|Bacteria	2|Bacteria	L	LAGLIDADG endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_1
YHH1_k127_1567202_1	445972.ANACOL_02699	2.46e-22	102.0	2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,24K1H@186801|Clostridia,3WJW5@541000|Ruminococcaceae	186801|Clostridia	S	non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1586655_0	697281.Mahau_0302	5.137e-102	347.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,42FCG@68295|Thermoanaerobacterales	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH1_k127_1590895_0	1254432.SCE1572_30065	1.327e-09	70.0	COG1506@1|root,COG5184@1|root,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
YHH1_k127_1632265_0	1458427.BAWN01000015_gene996	8.979e-119	387.0	COG3617@1|root,COG3617@2|Bacteria,1QX1C@1224|Proteobacteria,2WIF0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
YHH1_k127_1641390_0	1172190.M947_10050	2.805e-10	62.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2YNDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH1_k127_1641390_1	392500.Swoo_1911	0.0002709	52.0	COG2374@1|root,COG3291@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria,1MX52@1224|Proteobacteria,1RMHH@1236|Gammaproteobacteria,2Q99Y@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM PKD domain containing protein	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD,PKD
YHH1_k127_1651020_0	479434.Sthe_2726	1.054e-60	216.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH1_k127_1651020_1	1278309.KB907100_gene2312	2.046e-07	61.0	COG1378@1|root,COG1378@2|Bacteria,1PZ3N@1224|Proteobacteria,1RS6X@1236|Gammaproteobacteria,1XITG@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_1782817_0	1071085.KK033114_gene1644	1.881e-13	83.0	COG2304@1|root,arCOG02902@2157|Archaea,2XZJD@28890|Euryarchaeota,23X73@183963|Halobacteria	183963|Halobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
YHH1_k127_1806815_1	340099.Teth39_2233	7.534e-15	83.0	2DQGV@1|root,336S4@2|Bacteria,1VJ0B@1239|Firmicutes,24QJF@186801|Clostridia,42H71@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1806815_0	1449355.JQNR01000005_gene4402	1.286e-29	128.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
YHH1_k127_1831270_0	867845.KI911784_gene1413	4.943e-82	287.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi,3751V@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YHH1_k127_1831270_1	195103.CPF_1940	6.326e-81	282.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,36EJE@31979|Clostridiaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
YHH1_k127_1854334_0	1211844.CBLM010000101_gene288	3.19e-22	108.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,3VNR3@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YHH1_k127_1880899_1	1501391.LG35_03050	4.573e-41	159.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,2FNF4@200643|Bacteroidia,22V7J@171550|Rikenellaceae	976|Bacteroidetes	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
YHH1_k127_1880899_0	506534.Rhein_2153	6.567e-67	236.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1WW0C@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
YHH1_k127_1880899_2	1521187.JPIM01000002_gene3182	6.16e-18	94.0	COG0461@1|root,COG0461@2|Bacteria,2G8R2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
YHH1_k127_1896408_0	331678.Cphamn1_2371	2.388e-103	354.0	COG5421@1|root,COG5421@2|Bacteria,1FF95@1090|Chlorobi	1090|Chlorobi	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH1_k127_1906931_0	264732.Moth_1254	9.831e-50	187.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,42EVU@68295|Thermoanaerobacterales	186801|Clostridia	S	beta-lactamase domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
YHH1_k127_1906931_1	309807.SRU_1720	4.233e-35	136.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1FK37@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH1_k127_1908093_0	795666.MW7_2044	7.829e-09	64.0	COG1378@1|root,COG1378@2|Bacteria,1PZ3N@1224|Proteobacteria,2W570@28216|Betaproteobacteria,1K7M5@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_1931687_0	1323361.JPOC01000024_gene1119	3.009e-107	357.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4FW5H@85025|Nocardiaceae	201174|Actinobacteria	EH	Amino-transferase class IV	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YHH1_k127_1931687_1	940282.CADQ01000022_gene2219	0.0005356	50.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2TVD3@28211|Alphaproteobacteria,2JTHR@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
YHH1_k127_1970768_3	1690.BPSG_0796	0.0003248	47.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CZ6S@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
YHH1_k127_1970768_1	1266914.ATUK01000010_gene1490	1.311e-46	184.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales	135613|Chromatiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
YHH1_k127_1970768_0	1121012.AUKX01000064_gene1065	8.195e-168	542.0	COG5421@1|root,COG5421@2|Bacteria,4PAGJ@976|Bacteroidetes,1IAIH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH1_k127_1970768_2	1537915.JU57_02855	8.827e-23	102.0	COG2337@1|root,COG2337@2|Bacteria,1Q23M@1224|Proteobacteria,42UXQ@68525|delta/epsilon subdivisions,2YPYA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH1_k127_2017899_1	926550.CLDAP_05110	7.573e-31	130.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
YHH1_k127_2017899_0	330214.NIDE4261	3.588e-59	213.0	COG0852@1|root,COG3261@1|root,COG0852@2|Bacteria,COG3261@2|Bacteria,3J0W2@40117|Nitrospirae	40117|Nitrospirae	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
YHH1_k127_2085295_1	525904.Tter_0916	4.025e-09	60.0	COG1314@1|root,COG1314@2|Bacteria,2NS1U@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase SecG subunit	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
YHH1_k127_2085295_0	309801.trd_0782	6.238e-40	160.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XPP@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YHH1_k127_2109573_3	10228.TriadP34780	5.169e-43	164.0	COG0536@1|root,KOG1489@2759|Eukaryota,38B68@33154|Opisthokonta,3BGKJ@33208|Metazoa	33208|Metazoa	S	GTP1/OBG	-	-	-	-	-	-	-	-	-	-	-	-	GTP1_OBG,MMR_HSR1
YHH1_k127_2109573_0	309799.DICTH_1040	1.803e-112	379.0	COG0064@1|root,COG0064@2|Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.12,6.3.5.6,6.3.5.7	ko:K01876,ko:K02434	ko00970,ko01100,map00970,map01100	M00359,M00360	R03905,R04212,R05577	RC00010,RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GatB_N,GatB_Yqey
YHH1_k127_2109573_2	1410616.JHXE01000002_gene1036	3.492e-75	271.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3NGY5@46205|Pseudobutyrivibrio	186801|Clostridia	C	ATP synthase delta (OSCP) subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
YHH1_k127_2109573_5	331104.BLBBGE_562	8.539e-05	53.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia,3IV7F@39782|Blattabacteriaceae	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
YHH1_k127_2109573_1	1458462.JNLK01000001_gene923	2.994e-110	372.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,27IDF@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH1_k127_2109573_4	1121017.AUFG01000006_gene1103	3.865e-05	49.0	COG0355@1|root,COG0355@2|Bacteria,2IHNZ@201174|Actinobacteria,4FHIU@85021|Intrasporangiaceae	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
YHH1_k127_2203428_9	493475.GARC_2376	2.238e-17	87.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	META
YHH1_k127_2203428_4	331113.SNE_A08140	8.411e-42	166.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YHH1_k127_2203428_3	1408473.JHXO01000005_gene1669	5.169e-43	164.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,2FT1X@200643|Bacteroidia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
YHH1_k127_2203428_1	1173027.Mic7113_5594	6.473e-97	327.0	COG0057@1|root,COG0057@2|Bacteria,1G1CS@1117|Cyanobacteria,1H7J0@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
YHH1_k127_2203428_0	1321778.HMPREF1982_03934	2.962e-122	417.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,267N0@186813|unclassified Clostridiales	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
YHH1_k127_2203428_8	357808.RoseRS_3979	1.848e-26	123.0	COG2866@1|root,COG5479@1|root,COG2866@2|Bacteria,COG5479@2|Bacteria,2GB4F@200795|Chloroflexi,3751R@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
YHH1_k127_2203428_5	526222.Desal_1487	3.728e-40	152.0	COG2246@1|root,COG2246@2|Bacteria,1Q28J@1224|Proteobacteria,43ER8@68525|delta/epsilon subdivisions,2X9KU@28221|Deltaproteobacteria,2MFRF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
YHH1_k127_2203428_11	1232437.KL662010_gene1593	1.744e-12	71.0	COG2840@1|root,COG2840@2|Bacteria,1RHC4@1224|Proteobacteria,42SUI@68525|delta/epsilon subdivisions,2WP6R@28221|Deltaproteobacteria,2MKC7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
YHH1_k127_2203428_2	237368.SCABRO_00086	5.898e-85	289.0	COG2887@1|root,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K10742	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	AAA_24,PDDEXK_1
YHH1_k127_2203428_10	472759.Nhal_2487	3.486e-13	77.0	COG3809@1|root,COG3809@2|Bacteria,1NIWT@1224|Proteobacteria	1224|Proteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
YHH1_k127_2203428_7	1500890.JQNL01000001_gene2620	9.234e-29	126.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1X48D@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
YHH1_k127_2278503_0	768671.ThimaDRAFT_4485	1.232e-10	73.0	COG0265@1|root,COG1075@1|root,COG2304@1|root,COG0265@2|Bacteria,COG1075@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	MA20_07505	-	1.1.3.6,1.6.5.3,3.4.21.107	ko:K00337,ko:K03333,ko:K04771,ko:K07114	ko00190,ko00984,ko01100,ko01120,ko01503,ko02020,map00190,map00984,map01100,map01120,map01503,map02020	M00144,M00728	R01459,R11945	RC00061,RC00146	ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03110	1.A.13.2.2,1.A.13.2.3,3.D.1	-	-	DUF1194
YHH1_k127_2296197_1	1179773.BN6_69040	1.874e-33	136.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4DXVK@85010|Pseudonocardiales	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YHH1_k127_2296197_0	904314.SEVCU012_1001	1.995e-66	237.0	COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H9W1@91061|Bacilli,4GYDU@90964|Staphylococcaceae	91061|Bacilli	O	Alkyl hydroperoxide reductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
YHH1_k127_2304947_1	472759.Nhal_1552	5.729e-08	62.0	2C578@1|root,32RF7@2|Bacteria,1NCG3@1224|Proteobacteria,1STJE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2304947_0	904314.SEVCU012_0702	3.371e-08	59.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,4GXBW@90964|Staphylococcaceae	91061|Bacilli	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_2329058_1	573370.DMR_42770	6.67e-21	106.0	COG0438@1|root,COG0438@2|Bacteria,1RH5W@1224|Proteobacteria,42UY3@68525|delta/epsilon subdivisions,2WQ9B@28221|Deltaproteobacteria,2MA2D@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_2329058_0	512565.AMIS_4830	8.868e-34	134.0	COG0451@1|root,COG0451@2|Bacteria,2IDW2@201174|Actinobacteria,4DCDP@85008|Micromonosporales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH1_k127_2342812_2	189425.PGRAT_19435	1.9e-05	51.0	2DSVM@1|root,33HKD@2|Bacteria,1VKN1@1239|Firmicutes,4IB8U@91061|Bacilli,273W7@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2342812_1	1123263.AUKY01000110_gene1057	7.132e-35	143.0	2ETSK@1|root,33MA0@2|Bacteria,1VN3Q@1239|Firmicutes,3VU1W@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2342812_0	1262915.BN574_01773	4.12e-61	220.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H28A@909932|Negativicutes	909932|Negativicutes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH1_k127_235718_0	425400.LS65_02435	3.624e-07	62.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2YMII@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YHH1_k127_2370437_0	744872.Spica_0889	8.752e-42	160.0	COG1373@1|root,COG1373@2|Bacteria,2J6SC@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_2370437_1	1499967.BAYZ01000124_gene2568	2.521e-32	135.0	COG3647@1|root,COG3647@2|Bacteria	2|Bacteria	S	Membrane	yjdF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
YHH1_k127_2374490_2	1198114.AciX9_0294	4.723e-12	74.0	COG0358@1|root,COG0358@2|Bacteria,3Y366@57723|Acidobacteria,2JIHT@204432|Acidobacteriia	204432|Acidobacteriia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
YHH1_k127_2374490_1	269482.Bcep1808_4568	4.72e-16	89.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1,HTH_Tnp_IS630
YHH1_k127_2374490_0	1461577.CCMH01000037_gene64	3.002e-91	314.0	COG0507@1|root,COG0640@1|root,COG0507@2|Bacteria,COG0640@2|Bacteria,4NF6J@976|Bacteroidetes,1HZ14@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	HRDC,HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
YHH1_k127_2403754_0	1247963.JPHU01000002_gene2674	1.612e-32	135.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
YHH1_k127_2414907_1	1200557.JHWV01000017_gene793	3.708e-22	103.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4H4ZR@909932|Negativicutes	909932|Negativicutes	S	Hydrolase, P-loop family	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
YHH1_k127_2414907_0	670487.Ocepr_1055	1.858e-147	496.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1WIA1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,Taq-exonuc
YHH1_k127_24211_0	511051.CSE_06310	1.043e-74	268.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	DUF3318,Peptidase_M48
YHH1_k127_24211_1	1163671.JAGI01000001_gene373	2.403e-12	72.0	COG4997@1|root,COG4997@2|Bacteria,1VEG6@1239|Firmicutes,24QRF@186801|Clostridia,36KRV@31979|Clostridiaceae	186801|Clostridia	S	phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF429,MazG-like
YHH1_k127_243046_1	886293.Sinac_0977	3.564e-14	78.0	COG3668@1|root,COG3668@2|Bacteria,2J4SU@203682|Planctomycetes	2|Bacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
YHH1_k127_243046_3	587753.EY04_10730	1.255e-09	62.0	COG3609@1|root,COG3609@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
YHH1_k127_243046_4	292459.STH476	4.553e-06	55.0	COG0268@1|root,COG0268@2|Bacteria	2|Bacteria	J	rRNA binding	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
YHH1_k127_243046_2	136993.KB900626_gene640	1.654e-11	68.0	COG3668@1|root,COG3668@2|Bacteria,1N7G9@1224|Proteobacteria,2UIC2@28211|Alphaproteobacteria,370YQ@31993|Methylocystaceae	28211|Alphaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH1_k127_243046_0	767817.Desgi_1790	2.714e-32	134.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,26290@186807|Peptococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
YHH1_k127_243046_5	429009.Adeg_1569	0.0007936	44.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,42ETI@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_2433224_0	983545.Glaag_1970	4.08e-63	233.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1FK@1236|Gammaproteobacteria,46D7C@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
YHH1_k127_2487342_1	278957.ABEA03000104_gene340	8.776e-22	103.0	COG1203@1|root,COG3177@1|root,COG1203@2|Bacteria,COG3177@2|Bacteria,46YK9@74201|Verrucomicrobia,3K9RV@414999|Opitutae	414999|Opitutae	L	DEAD-like helicases superfamily	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
YHH1_k127_2487342_0	331113.SNE_A22970	2.368e-77	276.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
YHH1_k127_2488595_2	1449126.JQKL01000049_gene2647	1.086e-20	100.0	COG1943@1|root,COG1943@2|Bacteria,1V6R5@1239|Firmicutes,24NQE@186801|Clostridia	186801|Clostridia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
YHH1_k127_2488595_0	926550.CLDAP_02840	2.385e-55	205.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
YHH1_k127_2503733_1	1122194.AUHU01000004_gene1450	2.002e-14	82.0	COG5274@1|root,COG5274@2|Bacteria,1NACU@1224|Proteobacteria,1SETD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CI	Cytochrome b5-like Heme/Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
YHH1_k127_2503733_0	118163.Ple7327_2411	8.951e-55	199.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,3VN4P@52604|Pleurocapsales	1117|Cyanobacteria	G	Raf kinase inhibitor-like protein, YbhB YbcL family	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
YHH1_k127_2503733_2	744980.TRICHSKD4_4588	1.419e-12	70.0	COG0625@1|root,COG0625@2|Bacteria	2|Bacteria	O	glutathione transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3,Glutaredoxin
YHH1_k127_2503733_3	932678.THERU_05645	8.271e-07	54.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	CP_0257	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
YHH1_k127_2503733_4	335543.Sfum_2068	9.713e-05	50.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,2MQHX@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
YHH1_k127_2544403_2	1384056.N787_03655	3.771e-06	58.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1X4W3@135614|Xanthomonadales	135614|Xanthomonadales	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
YHH1_k127_2544403_0	366394.Smed_5147	1.231e-22	107.0	COG3568@1|root,COG3568@2|Bacteria,1Q1Q1@1224|Proteobacteria,2U28J@28211|Alphaproteobacteria,4BAH9@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH1_k127_2544403_1	1237149.C900_00014	2.368e-06	59.0	COG3930@1|root,COG3930@2|Bacteria,4NG5D@976|Bacteroidetes	976|Bacteroidetes	E	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
YHH1_k127_2574210_0	266265.Bxe_C0539	3.207e-05	54.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2VS1H@28216|Betaproteobacteria,1K0AD@119060|Burkholderiaceae	28216|Betaproteobacteria	G	6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
YHH1_k127_2574477_3	525904.Tter_1085	9.939e-17	84.0	COG1738@1|root,COG1738@2|Bacteria,2NQ6M@2323|unclassified Bacteria	2|Bacteria	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	yhhQ	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
YHH1_k127_2574477_5	265729.GS18_0205525	4.067e-10	69.0	COG1372@1|root,COG1372@2|Bacteria,1VPYF@1239|Firmicutes,4HSTN@91061|Bacilli,1ZEPN@1386|Bacillus	91061|Bacilli	L	LAGLIDADG-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_3
YHH1_k127_2574477_1	1423775.BAMN01000006_gene959	1.963e-22	106.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,3F6K4@33958|Lactobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
YHH1_k127_2574477_0	1232452.BAIB02000006_gene1195	1.193e-39	159.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,268HU@186813|unclassified Clostridiales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH1_k127_2574477_2	1121472.AQWN01000007_gene1058	4.936e-22	101.0	COG1569@1|root,COG1569@2|Bacteria,1VHAV@1239|Firmicutes,24QPU@186801|Clostridia,2671I@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH1_k127_2574477_4	75379.Tint_2136	1.102e-12	68.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,1KIUJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
YHH1_k127_257503_0	258052.JNYV01000003_gene5101	4.392e-130	423.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,2M066@2063|Kitasatospora	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YHH1_k127_2586475_0	1230342.CTM_22409	2.171e-23	109.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,36FE7@31979|Clostridiaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	oxaA	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
YHH1_k127_2586475_1	1392487.JIAD01000001_gene1458	7.149e-15	81.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,25UVE@186806|Eubacteriaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
YHH1_k127_2590871_0	2754.EH55_06205	1.39e-44	166.0	COG0281@1|root,COG0281@2|Bacteria,3T9QC@508458|Synergistetes	508458|Synergistetes	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
YHH1_k127_2590871_1	926550.CLDAP_18870	1.112e-11	69.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
YHH1_k127_2599782_0	269799.Gmet_1395	4.664e-71	256.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,43TBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH1_k127_2599782_1	1385515.N791_12550	2.149e-23	105.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1X36S@135614|Xanthomonadales	135614|Xanthomonadales	NU	General secretion pathway protein	xpsE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
YHH1_k127_2636776_0	1122214.AQWH01000009_gene1970	3.894e-32	132.0	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2U78A@28211|Alphaproteobacteria,2PKVN@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	SNARE associated Golgi protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH1_k127_2642583_1	546269.HMPREF0389_00586	5.758e-09	66.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia	186801|Clostridia	L	'dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
YHH1_k127_2642583_0	203119.Cthe_2256	3.203e-34	144.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WH8B@541000|Ruminococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
YHH1_k127_2669300_0	1463841.JOIR01000011_gene2697	2.306e-135	446.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
YHH1_k127_2669534_0	1173022.Cri9333_0603	9.228e-14	78.0	COG1432@1|root,COG1432@2|Bacteria,1G01P@1117|Cyanobacteria,1H7R9@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG1432 conserved	-	-	-	-	-	-	-	-	-	-	-	-	NYN
YHH1_k127_2669534_1	521045.Kole_0364	0.0003282	49.0	COG2801@1|root,COG2801@2|Bacteria,2GEBC@200918|Thermotogae	200918|Thermotogae	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH1_k127_2710762_0	1231190.NA8A_20617	0.0001648	53.0	COG0477@1|root,COG0477@2|Bacteria,1MWUR@1224|Proteobacteria,2TT7N@28211|Alphaproteobacteria,43RT2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
YHH1_k127_2711401_4	1111121.HMPREF1247_0490	2.505e-27	122.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CU8U@84998|Coriobacteriia	84998|Coriobacteriia	D	Part of the ABC transporter FtsEX involved in cellular division	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
YHH1_k127_2711401_2	580331.Thit_1777	1.079e-71	249.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,42EW3@68295|Thermoanaerobacterales	186801|Clostridia	D	TIGRFAM Cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
YHH1_k127_2711401_1	1229172.JQFA01000002_gene2180	3.947e-74	259.0	COG1186@1|root,COG1186@2|Bacteria,1G1QH@1117|Cyanobacteria,1H7IP@1150|Oscillatoriales	1117|Cyanobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH1_k127_2711401_6	243164.DET1552	0.0008041	47.0	COG1961@1|root,COG1961@2|Bacteria,2G7BH@200795|Chloroflexi,34DMJ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH1_k127_2711401_3	714943.Mucpa_4856	2.171e-41	159.0	COG3476@1|root,COG3476@2|Bacteria,4NP0D@976|Bacteroidetes,1ITBI@117747|Sphingobacteriia	976|Bacteroidetes	T	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	tspO	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
YHH1_k127_2711401_5	194439.CT0599	9.711e-22	100.0	2E3B5@1|root,32YAP@2|Bacteria,1FE8N@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
YHH1_k127_2711401_0	1449126.JQKL01000014_gene2985	3.437e-99	333.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,268B4@186813|unclassified Clostridiales	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
YHH1_k127_275791_0	710687.KI912270_gene6185	2.285e-36	151.0	COG1251@1|root,COG1251@2|Bacteria,2I3CF@201174|Actinobacteria,23F56@1762|Mycobacteriaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
YHH1_k127_2767577_0	273068.TTE1818	1.948e-144	480.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YHH1_k127_2793035_0	1541065.JRFE01000032_gene3666	5.059e-10	75.0	COG0689@1|root,COG1404@1|root,COG2931@1|root,COG0689@2|Bacteria,COG1404@2|Bacteria,COG2931@2|Bacteria,1G7IS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,Peptidase_S8
YHH1_k127_2793035_1	1484460.JSWG01000015_gene1026	0.0006007	55.0	COG1345@1|root,COG1361@1|root,COG3227@1|root,COG3420@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3227@2|Bacteria,COG3420@2|Bacteria,COG3897@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
YHH1_k127_2804789_0	1121382.JQKG01000006_gene3542	3.852e-70	250.0	COG3291@1|root,COG3325@1|root,COG5297@1|root,COG3291@2|Bacteria,COG3325@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.1.3.5,3.2.1.14,3.2.1.4	ko:K01081,ko:K01179,ko:K01183,ko:K20276	ko00230,ko00240,ko00500,ko00520,ko00760,ko01100,ko01110,ko02024,map00230,map00240,map00500,map00520,map00760,map01100,map01110,map02024	-	R00183,R00511,R00963,R01126,R01206,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02334,R02719,R03346,R06200,R11307,R11308	RC00017,RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	CBM_2,Cellulase,Glyco_hydro_18,PKD,Trypsin_2,fn3
YHH1_k127_2822259_0	330214.NIDE4265	4.228e-132	437.0	COG0651@1|root,COG0651@2|Bacteria,3J0HR@40117|Nitrospirae	40117|Nitrospirae	CP	Proton-conducting membrane transporter	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
YHH1_k127_2822259_1	593750.Metfor_2100	3.742e-50	184.0	COG3260@1|root,arCOG01553@2157|Archaea,2Y8IV@28890|Euryarchaeota,2NAV7@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM NADH ubiquinone oxidoreductase, 20	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
YHH1_k127_2826581_0	1056820.KB900681_gene2859	5.855e-130	427.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH1_k127_2843677_0	2045.KR76_13505	6.814e-134	436.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4DP2I@85009|Propionibacteriales	201174|Actinobacteria	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase,HTH_3
YHH1_k127_2873357_3	883112.HMPREF9707_01371	7.255e-05	53.0	COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes,4HI8Y@91061|Bacilli,27EWY@186827|Aerococcaceae	91061|Bacilli	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
YHH1_k127_2873357_0	1249627.D779_1075	1.286e-195	618.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1WW9T@135613|Chromatiales	135613|Chromatiales	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
YHH1_k127_2873357_2	502025.Hoch_6401	1.188e-15	87.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	ko:K03496,ko:K22491	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	B12-binding_2,DUF3967,HTH_17,MerR_1
YHH1_k127_2873357_1	1121382.JQKG01000039_gene77	8.15e-19	91.0	COG2335@1|root,COG2335@2|Bacteria,1WMNY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
YHH1_k127_2944513_0	373903.Hore_04460	1.459e-66	246.0	COG0610@1|root,COG1196@1|root,COG0610@2|Bacteria,COG1196@2|Bacteria,1TP7S@1239|Firmicutes,248A6@186801|Clostridia,3WBET@53433|Halanaerobiales	186801|Clostridia	L	Type I restriction enzyme R Protein	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
YHH1_k127_2994439_0	696369.KI912183_gene938	7.104e-07	57.0	COG0500@1|root,COG2226@2|Bacteria,1U5XV@1239|Firmicutes,24A44@186801|Clostridia,260HI@186807|Peptococcaceae	186801|Clostridia	Q	Hypothetical methyltransferase	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
YHH1_k127_2994439_1	180332.JTGN01000006_gene3454	4.287e-06	59.0	COG1653@1|root,COG1653@2|Bacteria,1UV0J@1239|Firmicutes,24H7P@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
YHH1_k127_2994439_2	589924.Ferp_0484	1.61e-05	53.0	arCOG06161@1|root,arCOG06161@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3017175_1	1131269.AQVV01000036_gene1504	6.116e-28	115.0	COG0185@1|root,COG0185@2|Bacteria	2|Bacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
YHH1_k127_3017175_0	608506.COB47_0842	5.836e-89	301.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,42EWJ@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YHH1_k127_3073792_0	565033.GACE_1938	1.915e-39	163.0	COG1948@1|root,arCOG02284@2157|Archaea,2XT7B@28890|Euryarchaeota,245S0@183980|Archaeoglobi	183980|Archaeoglobi	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
YHH1_k127_3088230_0	697281.Mahau_0398	6.013e-24	117.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,42G6T@68295|Thermoanaerobacterales	186801|Clostridia	KL	SMART DEAD-like helicase	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
YHH1_k127_3099012_2	1089553.Tph_c06670	3.067e-12	74.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,42FI3@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
YHH1_k127_3099012_0	237368.SCABRO_03309	2.355e-72	252.0	COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH1_k127_3099012_1	1184607.AUCHE_24_00360	1.571e-21	102.0	COG0607@1|root,COG0607@2|Bacteria,2GR81@201174|Actinobacteria	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH1_k127_3099012_3	745718.JADT01000019_gene1519	3.183e-08	56.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
YHH1_k127_3103315_2	526218.Sterm_1909	1.048e-12	80.0	COG0515@1|root,COG0515@2|Bacteria	526218.Sterm_1909|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3103315_1	515635.Dtur_0538	2.147e-29	131.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
YHH1_k127_3103315_0	671143.DAMO_2877	1.102e-55	202.0	COG0745@1|root,COG0745@2|Bacteria,2NP9R@2323|unclassified Bacteria	2|Bacteria	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_3103315_4	552811.Dehly_1153	0.0001682	46.0	2EFVW@1|root,339N3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3103315_3	1044.EH31_01500	9.932e-12	76.0	COG3595@1|root,COG3595@2|Bacteria,1QUNK@1224|Proteobacteria,2TW1Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3108191_0	867903.ThesuDRAFT_00386	3.139e-16	84.0	COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia	186801|Clostridia	S	ATP cob(I)alamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
YHH1_k127_3108191_1	351016.RAZWK3B_05322	4.377e-07	61.0	COG1376@1|root,COG1376@2|Bacteria,1MUAB@1224|Proteobacteria,2TTXM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	ErfK YbiS YcfS YnhG family protein	MA20_01915	-	-	-	-	-	-	-	-	-	-	-	YkuD
YHH1_k127_3114674_0	1385935.N836_10275	2.689e-21	99.0	COG1610@1|root,COG1610@2|Bacteria,1G607@1117|Cyanobacteria,1HB1I@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
YHH1_k127_3114674_1	531844.FIC_01273	2.009e-16	84.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia	976|Bacteroidetes	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
YHH1_k127_3124399_1	1216967.L100_03772	2.167e-37	145.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1HWYD@117743|Flavobacteriia,34Q5Q@308865|Elizabethkingia	976|Bacteroidetes	L	Viral (Superfamily 1) RNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YHH1_k127_3124399_0	891968.Anamo_1519	4.871e-39	160.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,3T9T4@508458|Synergistetes	508458|Synergistetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
YHH1_k127_3168552_0	1304880.JAGB01000002_gene1539	2.725e-195	634.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
YHH1_k127_3168552_1	926692.AZYG01000040_gene1433	1.302e-05	55.0	COG2339@1|root,COG2339@2|Bacteria,1UZGQ@1239|Firmicutes,24D4U@186801|Clostridia,3WBU4@53433|Halanaerobiales	186801|Clostridia	S	Protease prsW family	prsW	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
YHH1_k127_3169681_1	570952.ATVH01000018_gene3347	5.732e-17	86.0	COG0717@1|root,COG0717@2|Bacteria,1MVDH@1224|Proteobacteria,2TR5U@28211|Alphaproteobacteria,2JQI3@204441|Rhodospirillales	204441|Rhodospirillales	F	2'-deoxycytidine 5'-triphosphate deaminase (DCD)	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
YHH1_k127_3169681_0	1122135.KB893170_gene2710	1.417e-24	104.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2U9GC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
YHH1_k127_3240600_0	247490.KSU1_D0118	1.636e-135	440.0	COG0366@1|root,COG0366@2|Bacteria,2IXJN@203682|Planctomycetes	203682|Planctomycetes	G	alpha amylase catalytic	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
YHH1_k127_3240600_5	1120999.JONM01000001_gene1505	1.148e-28	119.0	COG3293@1|root,COG3293@2|Bacteria,1PE1I@1224|Proteobacteria,2VSHY@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF4096
YHH1_k127_3240600_4	485913.Krac_0209	2.658e-61	214.0	COG3293@1|root,COG3293@2|Bacteria,2G7ZQ@200795|Chloroflexi	200795|Chloroflexi	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF4096
YHH1_k127_3240600_1	1288963.ADIS_1567	6.206e-100	335.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47K1Z@768503|Cytophagia	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
YHH1_k127_3240600_3	368408.Tpen_0856	2.992e-80	275.0	COG1013@1|root,arCOG01599@2157|Archaea,2XPQG@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
YHH1_k127_3240600_2	1365176.N186_06005	3.59e-84	289.0	COG0674@1|root,arCOG01606@2157|Archaea,2XPYK@28889|Crenarchaeota	28889|Crenarchaeota	C	pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
YHH1_k127_3245985_0	1111479.AXAR01000012_gene1397	7.557e-134	448.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,2786P@186823|Alicyclobacillaceae	91061|Bacilli	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YHH1_k127_3245985_1	243164.DET0404	2.378e-40	161.0	COG0030@1|root,COG0030@2|Bacteria,2G6ER@200795|Chloroflexi,34CIF@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YHH1_k127_3245985_2	794903.OPIT5_09560	1.352e-08	68.0	2A3ET@1|root,30RXG@2|Bacteria,46YBW@74201|Verrucomicrobia,3K9A2@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3305979_1	1122137.AQXF01000003_gene2379	1.019e-15	89.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
YHH1_k127_3305979_0	1162668.LFE_1578	1.696e-21	104.0	COG0130@1|root,COG0130@2|Bacteria,3J0KH@40117|Nitrospirae	40117|Nitrospirae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
YHH1_k127_3354971_1	1321779.HMPREF1984_01407	9.556e-48	183.0	COG2148@1|root,COG2148@2|Bacteria,378EQ@32066|Fusobacteria	32066|Fusobacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
YHH1_k127_3354971_0	246194.CHY_1057	3.66e-71	252.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia,42JFW@68295|Thermoanaerobacterales	186801|Clostridia	M	RmlD substrate binding domain	-	-	4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7	ko:K01784,ko:K02473,ko:K03274,ko:K08678	ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100	M00064,M00361,M00362,M00632	R00291,R00418,R01384,R02984,R05176	RC00289,RC00508,RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,GDP_Man_Dehyd
YHH1_k127_3354971_2	72664.XP_006396261.1	1.478e-20	100.0	COG0190@1|root,KOG0089@2759|Eukaryota,37K6Z@33090|Viridiplantae,3GFZP@35493|Streptophyta,3HSHM@3699|Brassicales	35493|Streptophyta	H	methenyltetrahydrofolate cyclohydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
YHH1_k127_3375419_10	637389.Acaty_c0561	0.0001081	48.0	2EB38@1|root,33540@2|Bacteria,1NBMZ@1224|Proteobacteria,1SFQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3375419_11	1469607.KK073768_gene4413	0.0002844	47.0	2A73B@1|root,30VYY@2|Bacteria,1GI7P@1117|Cyanobacteria,1HT79@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
YHH1_k127_3375419_2	46234.ANA_C11858	1.648e-36	141.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH1_k127_3375419_6	187303.BN69_0722	5.537e-18	86.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,36YK3@31993|Methylocystaceae	28211|Alphaproteobacteria	FL	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18
YHH1_k127_3375419_9	1227276.HMPREF9148_00421	1.626e-07	53.0	COG3617@1|root,COG3617@2|Bacteria,4NIG0@976|Bacteroidetes,2G3ES@200643|Bacteroidia	976|Bacteroidetes	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
YHH1_k127_3375419_0	402612.FP0483	8.241e-100	330.0	COG3617@1|root,COG3617@2|Bacteria,4NIG0@976|Bacteroidetes,1IJ7P@117743|Flavobacteriia,2NV2N@237|Flavobacterium	976|Bacteroidetes	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
YHH1_k127_3375419_1	1121889.AUDM01000008_gene726	1.193e-47	180.0	2DRYI@1|root,33DPS@2|Bacteria,4P2J3@976|Bacteroidetes	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH1_k127_3375419_7	243232.MJ_0435	1.815e-15	80.0	COG1669@1|root,arCOG01206@2157|Archaea,2Y03V@28890|Euryarchaeota	28890|Euryarchaeota	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
YHH1_k127_3375419_5	498848.TaqDRAFT_3958	1.147e-22	101.0	COG2361@1|root,COG2361@2|Bacteria,1WKJ0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function DUF86	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	DUF86,NTP_transf_2
YHH1_k127_3375419_4	880070.Cycma_3018	7.974e-32	129.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	nudI	-	3.6.1.55	ko:K03574,ko:K12944	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YHH1_k127_3375419_3	1121929.KB898672_gene4092	6.961e-33	134.0	COG2320@1|root,COG2320@2|Bacteria,1V3IB@1239|Firmicutes,4HKXN@91061|Bacilli	91061|Bacilli	S	GrpB protein	yqkA1	-	-	-	-	-	-	-	-	-	-	-	GrpB
YHH1_k127_3394733_7	1441930.Z042_06360	2.265e-05	56.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,400HD@613|Serratia	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH1_k127_3394733_6	1121929.KB898662_gene384	1.948e-05	55.0	COG0642@1|root,COG2205@2|Bacteria,1UZ8S@1239|Firmicutes,4HDAG@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YHH1_k127_3394733_4	1408439.JHXW01000006_gene991	2.408e-14	79.0	COG0745@1|root,COG0745@2|Bacteria,379HE@32066|Fusobacteria	32066|Fusobacteria	K	Psort location Cytoplasmic, score 9.97	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_3394733_5	666681.M301_2131	3.236e-14	77.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI6B@28216|Betaproteobacteria,2KKH4@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM response regulator receiver	-	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_3394733_0	1379698.RBG1_1C00001G1686	6.017e-249	783.0	COG1217@1|root,COG1217@2|Bacteria,2NNY7@2323|unclassified Bacteria	2|Bacteria	T	Elongation factor G C-terminus	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
YHH1_k127_3394733_1	123214.PERMA_0824	1.576e-101	349.0	COG2804@1|root,COG2804@2|Bacteria,2G4H7@200783|Aquificae	200783|Aquificae	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
YHH1_k127_3394733_2	765912.Thimo_0376	1.324e-56	201.0	COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,1SBIG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YHH1_k127_3394733_3	1121382.JQKG01000010_gene4721	1.503e-15	83.0	COG2323@1|root,COG2323@2|Bacteria,1WMG8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
YHH1_k127_3412414_1	1122129.AUEF01000010_gene1546	5.73e-10	63.0	COG1937@1|root,COG1937@2|Bacteria,1VFB9@1239|Firmicutes,4HNVQ@91061|Bacilli,4GZQQ@90964|Staphylococcaceae	91061|Bacilli	S	Metal-sensitive transcriptional repressor	csoR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
YHH1_k127_3412414_3	395493.BegalDRAFT_0441	7.61e-06	59.0	COG0845@1|root,COG0845@2|Bacteria,1MWZ9@1224|Proteobacteria,1RM91@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
YHH1_k127_3412414_0	118163.Ple7327_2901	1.177e-144	498.0	COG0841@1|root,COG0841@2|Bacteria,1G21T@1117|Cyanobacteria	1117|Cyanobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH1_k127_3412414_2	1280952.HJA_07727	7.266e-07	57.0	29M6H@1|root,3083Y@2|Bacteria,1RJTC@1224|Proteobacteria,2UC3J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3458558_0	521674.Plim_4113	1.411e-51	198.0	COG0322@1|root,COG0322@2|Bacteria,2IWVR@203682|Planctomycetes	203682|Planctomycetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
YHH1_k127_3458558_1	1121405.dsmv_3673	8.378e-51	197.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria,2MI9U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
YHH1_k127_3458558_2	512565.AMIS_26360	2.618e-20	94.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
YHH1_k127_3469198_0	32057.KB217478_gene2577	1.078e-66	237.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	CMAS,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25
YHH1_k127_3469198_1	743722.Sph21_0400	9.204e-26	116.0	COG1373@1|root,COG1373@2|Bacteria,4NG8U@976|Bacteroidetes,1ITM4@117747|Sphingobacteriia	976|Bacteroidetes	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_3493479_2	1499967.BAYZ01000148_gene1730	4.949e-07	53.0	COG2984@1|root,COG2984@2|Bacteria	2|Bacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
YHH1_k127_3493479_0	290317.Cpha266_2501	1.548e-82	284.0	COG0441@1|root,COG0441@2|Bacteria,1FDT4@1090|Chlorobi	1090|Chlorobi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
YHH1_k127_3493479_1	1236542.BALM01000025_gene2771	8.638e-36	138.0	COG0167@1|root,COG0167@2|Bacteria,1QC2A@1224|Proteobacteria,1T7Q8@1236|Gammaproteobacteria,2QDCB@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YHH1_k127_3498385_0	626939.HMPREF9443_00952	9.618e-107	357.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4H1XS@909932|Negativicutes	909932|Negativicutes	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH1_k127_3498385_1	1047013.AQSP01000118_gene1252	3.039e-80	293.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3499105_1	1307761.L21SP2_0083	2.467e-10	64.0	COG0406@1|root,COG0406@2|Bacteria,2J9E6@203691|Spirochaetes	203691|Spirochaetes	G	Phosphoglycerate mutase family	-	-	3.1.3.3,3.1.3.73,5.4.2.12	ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
YHH1_k127_3499105_0	362418.IW19_04150	3.893e-22	100.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,1I44D@117743|Flavobacteriia,2NWF6@237|Flavobacterium	976|Bacteroidetes	J	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YHH1_k127_3521019_0	1173022.Cri9333_3960	4.208e-48	180.0	COG0411@1|root,COG0411@2|Bacteria,1G3VI@1117|Cyanobacteria,1H8KA@1150|Oscillatoriales	1117|Cyanobacteria	E	Amino acid amide ABC transporter ATP-binding protein 1, HAAT family	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
YHH1_k127_3526951_0	1121451.DESAM_10036	8.742e-60	227.0	COG1518@1|root,COG3344@1|root,COG1518@2|Bacteria,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Q0C@68525|delta/epsilon subdivisions,2WIIZ@28221|Deltaproteobacteria,2MDPJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986,ko:K15342	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	Cas_Cas1,GIIM,RVT_1
YHH1_k127_3543479_0	1120973.AQXL01000114_gene699	5.526e-105	354.0	COG3387@1|root,COG3387@2|Bacteria,1V01W@1239|Firmicutes,4HCVG@91061|Bacilli	91061|Bacilli	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
YHH1_k127_3563857_0	1123257.AUFV01000009_gene2309	1.164e-73	255.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1X5AX@135614|Xanthomonadales	135614|Xanthomonadales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YHH1_k127_3577007_0	1183438.GKIL_0724	3.807e-11	70.0	COG0170@1|root,COG0170@2|Bacteria,1G25U@1117|Cyanobacteria	1117|Cyanobacteria	I	Dolichol kinase	-	GO:0003674,GO:0003824,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0006766,GO:0006775,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0010276,GO:0016101,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017144,GO:0018130,GO:0033306,GO:0034308,GO:0042360,GO:0042362,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1903173	2.7.1.182	ko:K18678	-	-	R10659	RC00002,RC00017	ko00000,ko01000	-	-	-	-
YHH1_k127_3600563_1	868131.MSWAN_0839	1.174e-05	55.0	arCOG06670@1|root,arCOG06670@2157|Archaea,2Y5UU@28890|Euryarchaeota,23PUE@183925|Methanobacteria	183925|Methanobacteria	L	NERD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NERD
YHH1_k127_3600563_0	290397.Adeh_4024	6.663e-34	134.0	COG2154@1|root,COG2154@2|Bacteria,1PT4Z@1224|Proteobacteria,42VFE@68525|delta/epsilon subdivisions,2WSE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YHH1_k127_3603320_1	59921.EU92_0463	8.111e-08	53.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1FZYN@1117|Cyanobacteria,1MM2S@1212|Prochloraceae	1117|Cyanobacteria	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
YHH1_k127_3603320_0	861299.J421_0421	7.258e-10	65.0	COG2308@1|root,COG2308@2|Bacteria,1ZT4M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
YHH1_k127_3616424_0	1284352.AOIG01000003_gene946	1.546e-122	406.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,26RI3@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the formation of phosphoenolpyruvate from pyruvate	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
YHH1_k127_3616424_4	386456.JQKN01000018_gene612	6.163e-28	124.0	COG0616@1|root,arCOG01311@2157|Archaea,2XTG8@28890|Euryarchaeota,23PIF@183925|Methanobacteria	183925|Methanobacteria	O	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
YHH1_k127_3616424_7	118168.MC7420_1914	5.235e-08	63.0	2DRBA@1|root,33B2N@2|Bacteria,1GAYX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3616424_3	525904.Tter_2736	2.229e-28	122.0	COG1525@1|root,COG1525@2|Bacteria,2NQ3M@2323|unclassified Bacteria	2|Bacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Ada_Zn_binding,SNase
YHH1_k127_3616424_5	1121897.AUGO01000008_gene2635	1.569e-23	105.0	2A8XB@1|root,30Y0U@2|Bacteria,4NSDA@976|Bacteroidetes,1I4EZ@117743|Flavobacteriia,2NY54@237|Flavobacterium	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YHH1_k127_3616424_2	944479.JQLX01000010_gene634	8.937e-43	163.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42SP5@68525|delta/epsilon subdivisions,2X6X9@28221|Deltaproteobacteria,2M7KU@213113|Desulfurellales	28221|Deltaproteobacteria	K	Peptidase S24-like	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
YHH1_k127_3616424_6	305900.GV64_12505	3.396e-11	70.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,1S5X5@1236|Gammaproteobacteria,1XJY4@135619|Oceanospirillales	135619|Oceanospirillales	KT	Belongs to the peptidase S24 family	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
YHH1_k127_3616424_1	1203611.KB894544_gene2213	5.879e-43	164.0	COG0389@1|root,COG0389@2|Bacteria,4NGPH@976|Bacteroidetes,2FPC7@200643|Bacteroidia,22U0Y@171550|Rikenellaceae	976|Bacteroidetes	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
YHH1_k127_3622276_0	868595.Desca_0481	7.719e-190	607.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2611G@186807|Peptococcaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YHH1_k127_3682515_1	118161.KB235922_gene4194	8.115e-33	134.0	COG0691@1|root,COG0691@2|Bacteria,1G542@1117|Cyanobacteria,3VJN0@52604|Pleurocapsales	1117|Cyanobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YHH1_k127_3682515_0	1300345.LF41_718	3.728e-92	312.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria,1X34A@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the class I fructose-bisphosphate aldolase family	-	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
YHH1_k127_369308_1	858215.Thexy_1429	9.413e-20	91.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,42EMN@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
YHH1_k127_369308_2	1347087.CBYO010000017_gene2725	6.04e-18	91.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli	91061|Bacilli	O	Required for disulfide bond formation in some proteins	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
YHH1_k127_369308_0	118166.JH976538_gene5109	8.583e-27	115.0	COG4243@1|root,COG4243@2|Bacteria,1FZWT@1117|Cyanobacteria,1H90D@1150|Oscillatoriales	1117|Cyanobacteria	CO	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
YHH1_k127_3696567_1	380703.AHA_3705	2.792e-13	82.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,1RQBF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
YHH1_k127_3696567_0	526222.Desal_3737	6.484e-29	121.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WPB9@28221|Deltaproteobacteria,2MG7M@213115|Desulfovibrionales	28221|Deltaproteobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
YHH1_k127_3697957_2	1123261.AXDW01000016_gene3103	0.0007271	52.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1X40P@135614|Xanthomonadales	135614|Xanthomonadales	M	murein transglycosylase	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
YHH1_k127_3697957_1	1307761.L21SP2_1448	1.069e-23	117.0	COG1825@1|root,COG1825@2|Bacteria,2J75H@203691|Spirochaetes	203691|Spirochaetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
YHH1_k127_3697957_0	349521.HCH_06817	4.626e-36	150.0	COG0524@1|root,COG0524@2|Bacteria,1QTMT@1224|Proteobacteria,1S1JQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH1_k127_369891_0	635013.TherJR_2864	3.748e-13	81.0	COG4733@1|root,COG4932@1|root,COG4733@2|Bacteria,COG4932@2|Bacteria,1UTKZ@1239|Firmicutes,253GX@186801|Clostridia	186801|Clostridia	C	SMART Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1,Pur_ac_phosph_N
YHH1_k127_3722413_0	1121428.DESHY_60062___1	6.495e-09	68.0	COG2165@1|root,COG2165@2|Bacteria,1W5JZ@1239|Firmicutes,256FM@186801|Clostridia	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH1_k127_3726314_0	1382356.JQMP01000003_gene2509	1.169e-29	126.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XPP@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YHH1_k127_3726314_1	485913.Krac_8434	2.43e-08	59.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
YHH1_k127_3726314_2	767817.Desgi_1201	3.002e-05	48.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,262FV@186807|Peptococcaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YHH1_k127_3755539_2	1124780.ANNU01000036_gene62	9.908e-09	63.0	COG2246@1|root,COG2246@2|Bacteria,4NXZ2@976|Bacteroidetes	976|Bacteroidetes	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
YHH1_k127_3755539_1	1380391.JIAS01000015_gene222	2.856e-101	338.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2TRRT@28211|Alphaproteobacteria,2JPZ6@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family 2	-	-	2.4.1.83,2.4.2.53	ko:K00721,ko:K10012	ko00510,ko00520,ko01100,ko01503,map00510,map00520,map01100,map01503	M00721,M00761	R01009,R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
YHH1_k127_3755539_0	886293.Sinac_2659	3.316e-122	407.0	COG0367@1|root,COG0367@2|Bacteria,2J23D@203682|Planctomycetes	203682|Planctomycetes	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
YHH1_k127_375787_0	264732.Moth_1550	5.84e-23	102.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,42FQ9@68295|Thermoanaerobacterales	186801|Clostridia	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
YHH1_k127_375787_1	745277.GRAQ_03826	1.428e-06	55.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,3FFAI@34037|Rahnella	1236|Gammaproteobacteria	U	general secretion pathway protein G	gspG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
YHH1_k127_3762613_0	204536.SULAZ_1122	2.813e-20	102.0	COG2801@1|root,COG2801@2|Bacteria,2G3YF@200783|Aquificae	200783|Aquificae	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,HTH_Tnp_Tc3_2,rve,rve_3
YHH1_k127_376718_0	1056820.KB900681_gene2859	4.543e-23	100.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH1_k127_376718_1	1463917.JODC01000006_gene7962	3.298e-21	99.0	2BU85@1|root,32PHM@2|Bacteria,2IP49@201174|Actinobacteria	201174|Actinobacteria	S	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH1_k127_376718_2	439481.Aboo_0623	2.703e-10	70.0	COG1437@1|root,arCOG01723@2157|Archaea,2XYQS@28890|Euryarchaeota,3F3BY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	TIGRFAM adenylyl cyclase CyaB	cyaB	GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
YHH1_k127_3767782_0	929556.Solca_3424	1.668e-96	339.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,1IPF7@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH1_k127_3786692_0	626887.J057_06481	5.889e-88	300.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1RNVK@1236|Gammaproteobacteria,4674G@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrB	GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
YHH1_k127_3803894_5	1131266.ARWQ01000006_gene271	4.207e-05	51.0	arCOG03272@1|root,arCOG03272@2157|Archaea,41T3V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3803894_0	1040989.AWZU01000035_gene1781	1.036e-146	489.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2TRVJ@28211|Alphaproteobacteria,3JQUM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
YHH1_k127_3803894_1	755732.Fluta_3120	3.437e-64	243.0	COG2357@1|root,COG2357@2|Bacteria,4NY1Y@976|Bacteroidetes,1IBNM@117743|Flavobacteriia	976|Bacteroidetes	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
YHH1_k127_3803894_3	1173263.Syn7502_03321	9.117e-12	75.0	COG0793@1|root,COG0793@2|Bacteria,1G1XG@1117|Cyanobacteria,1H3Y6@1129|Synechococcus	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	ctpA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
YHH1_k127_3803894_4	430498.S8A2Q0	4.114e-05	54.0	COG0461@1|root,KOG1377@2759|Eukaryota,39WUY@33154|Opisthokonta,3NY1H@4751|Fungi,3QR2R@4890|Ascomycota	4751|Fungi	F	Orotate phosphoribosyltransferase	URA5	GO:0003674,GO:0003824,GO:0004588,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YHH1_k127_3803894_2	1089550.ATTH01000001_gene160	2.711e-14	78.0	COG2127@1|root,COG2127@2|Bacteria,4PERZ@976|Bacteroidetes,1FJHS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	ATP-dependent Clp protease adaptor protein ClpS	-	-	-	-	-	-	-	-	-	-	-	-	ClpS
YHH1_k127_3814397_0	368408.Tpen_1456	3.018e-85	297.0	COG0674@1|root,arCOG01606@2157|Archaea,2XPYK@28889|Crenarchaeota	28889|Crenarchaeota	C	pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
YHH1_k127_3814397_1	1121413.JMKT01000012_gene649	4.794e-09	64.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,42U69@68525|delta/epsilon subdivisions,2WQJZ@28221|Deltaproteobacteria,2MAU2@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hyhS	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
YHH1_k127_3914800_1	1089553.Tph_c00920	8.505e-05	48.0	COG1724@1|root,COG1724@2|Bacteria,1VKXG@1239|Firmicutes,24UW1@186801|Clostridia	186801|Clostridia	N	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH1_k127_3914800_0	1346330.M472_05465	1.791e-65	228.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1IP1Y@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH1_k127_3953384_1	1121904.ARBP01000066_gene2204	0.0002817	44.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH1_k127_3953384_0	443254.Marpi_0813	3.209e-11	68.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
YHH1_k127_3977959_1	266117.Rxyl_0312	2.347e-45	166.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4CQV5@84995|Rubrobacteria	84995|Rubrobacteria	EU	Peptidase S9, prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YHH1_k127_3977959_2	234621.RER_35410	1.174e-18	92.0	COG3070@1|root,COG3070@2|Bacteria,2GUYG@201174|Actinobacteria,4G417@85025|Nocardiaceae	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
YHH1_k127_3977959_0	494416.AYXN01000041_gene501	1.191e-105	357.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1RNVK@1236|Gammaproteobacteria,3NPI8@468|Moraxellaceae	1236|Gammaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrB	GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
YHH1_k127_4013979_1	1280.SAXN108_1890	1.978e-12	76.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,4GY3F@90964|Staphylococcaceae	91061|Bacilli	K	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH1_k127_4013979_0	1210908.HSB1_01510	2.056e-27	122.0	COG0428@1|root,arCOG00576@2157|Archaea,2XXNC@28890|Euryarchaeota,23YW7@183963|Halobacteria	183963|Halobacteria	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
YHH1_k127_4020355_0	986075.CathTA2_2484	8.705e-12	73.0	COG3327@1|root,COG3327@2|Bacteria,1TRBU@1239|Firmicutes,4HCP9@91061|Bacilli	91061|Bacilli	K	Phenylacetic acid degradation operon negative regulatory protein PaaX	paaX	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
YHH1_k127_4020355_1	391037.Sare_1169	2.545e-05	50.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4DCGD@85008|Micromonosporales	201174|Actinobacteria	L	helicase	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
YHH1_k127_4037265_0	1300345.LF41_1725	1.372e-53	207.0	COG5545@1|root,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,1S6W2@1236|Gammaproteobacteria,1X5QV@135614|Xanthomonadales	135614|Xanthomonadales	S	Virulence-associated protein E	-	-	-	-	-	-	-	-	-	-	-	-	VirE
YHH1_k127_4040488_0	216432.CA2559_06410	3.043e-23	106.0	COG2353@1|root,COG2353@2|Bacteria,4NMWH@976|Bacteroidetes,1I1TM@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
YHH1_k127_4040488_1	1504672.669787210	2.666e-08	55.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,4AABN@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
YHH1_k127_4048476_0	511.JT27_05480	2.972e-17	92.0	COG0683@1|root,COG0683@2|Bacteria,1NNXR@1224|Proteobacteria,2VTCQ@28216|Betaproteobacteria,3T2MJ@506|Alcaligenaceae	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YHH1_k127_4196995_0	796606.BMMGA3_02255	4.285e-110	383.0	COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,1ZS1A@1386|Bacillus	91061|Bacilli	M	Glycosyl transferase family group 2	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_hydro_18,Glyco_tranf_2_3,Glycos_transf_2,Polysacc_deac_1
YHH1_k127_4196995_2	749222.Nitsa_0916	2.034e-50	190.0	COG3868@1|root,COG3868@2|Bacteria,1PIK8@1224|Proteobacteria,42QZ4@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
YHH1_k127_4196995_4	1101188.KI912156_gene4050	2.275e-13	83.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CBM60,CBM9_1,Glyco_hydro_8,Polysacc_deac_1,SLH,SprB
YHH1_k127_4196995_3	1144275.COCOR_03740	1.205e-26	126.0	COG0726@1|root,COG0726@2|Bacteria,1Q6RX@1224|Proteobacteria,433P3@68525|delta/epsilon subdivisions,2WXCT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
YHH1_k127_4196995_1	796606.BMMGA3_02255	1.079e-54	208.0	COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,1ZS1A@1386|Bacillus	91061|Bacilli	M	Glycosyl transferase family group 2	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_hydro_18,Glyco_tranf_2_3,Glycos_transf_2,Polysacc_deac_1
YHH1_k127_4209300_0	555088.DealDRAFT_0489	1.108e-166	545.0	COG3387@1|root,COG3387@2|Bacteria,1TR12@1239|Firmicutes,248Q3@186801|Clostridia,42KAA@68298|Syntrophomonadaceae	186801|Clostridia	G	PFAM glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
YHH1_k127_4240261_0	700598.Niako_6249	2.536e-60	221.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1IQR6@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH1_k127_4240261_1	498761.HM1_1722	7.454e-08	61.0	COG0500@1|root,COG2226@2|Bacteria,1VAEA@1239|Firmicutes,24G83@186801|Clostridia	186801|Clostridia	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31,Ubie_methyltran
YHH1_k127_4254576_0	309807.SRU_1720	1.907e-35	142.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1FK37@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH1_k127_4258056_0	1397696.KK211189_gene930	7.061e-56	201.0	COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,3WG6A@539002|Bacillales incertae sedis	91061|Bacilli	G	6-phosphogluconate dehydrogenase	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
YHH1_k127_4258056_1	1122134.KB893650_gene763	1.576e-37	144.0	COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,1S8Z1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH1_k127_4269260_0	980584.AFPB01000016_gene603	6.691e-25	110.0	COG1943@1|root,COG1943@2|Bacteria,4PJWR@976|Bacteroidetes,1IGTZ@117743|Flavobacteriia,4076N@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_4281306_7	1121094.KB894673_gene2809	1.522e-06	55.0	COG1373@1|root,COG1373@2|Bacteria,4NG8U@976|Bacteroidetes,2FP3K@200643|Bacteroidia,4AM7Q@815|Bacteroidaceae	976|Bacteroidetes	S	ATPase (AAA superfamily)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_4281306_6	656519.Halsa_1358	2.581e-12	72.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,3WAYF@53433|Halanaerobiales	186801|Clostridia	L	PFAM Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
YHH1_k127_4281306_2	1089548.KI783301_gene959	1.272e-31	131.0	COG1670@1|root,COG1670@2|Bacteria,1V3W1@1239|Firmicutes,4HH6A@91061|Bacilli,3WETK@539002|Bacillales incertae sedis	91061|Bacilli	J	Acetyltransferase (GNAT) domain	speG	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YHH1_k127_4281306_5	240015.ACP_0608	1.128e-13	81.0	COG0077@1|root,COG0077@2|Bacteria,3Y49H@57723|Acidobacteria,2JJ3X@204432|Acidobacteriia	204432|Acidobacteriia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
YHH1_k127_4281306_3	1232410.KI421412_gene82	9.535e-18	85.0	COG2026@1|root,COG2026@2|Bacteria,1NP1I@1224|Proteobacteria,437H9@68525|delta/epsilon subdivisions,2WVKQ@28221|Deltaproteobacteria,43V3Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH1_k127_4281306_4	1206741.BAFX01000180_gene8263	9.335e-17	90.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria,4FVP4@85025|Nocardiaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH1_k127_4305280_0	1121335.Clst_0281	1.125e-93	321.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH1_k127_4305280_1	240302.BN982_03497	2.025e-24	115.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,3NE6S@45667|Halobacillus	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	vanYB	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
YHH1_k127_4311495_3	1234364.AMSF01000016_gene1627	7.063e-23	100.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1X7FC@135614|Xanthomonadales	135614|Xanthomonadales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH1_k127_4311495_2	661367.LLO_1326	7.235e-35	142.0	COG0077@1|root,COG0077@2|Bacteria,1PK3E@1224|Proteobacteria,1RXS0@1236|Gammaproteobacteria,1JDA9@118969|Legionellales	118969|Legionellales	E	Prephenate dehydratase	-	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
YHH1_k127_4311495_4	36874.HQ34_06375	8.418e-06	55.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,2FMWN@200643|Bacteroidia,22XMM@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YHH1_k127_4311495_0	572477.Alvin_2538	4.856e-124	404.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1WVZH@135613|Chromatiales	135613|Chromatiales	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
YHH1_k127_4311495_1	879308.HMPREF9130_1966	2.348e-73	252.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,22G88@1570339|Peptoniphilaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
YHH1_k127_4320925_1	585529.HMPREF0291_12215	0.0004873	46.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,22KJ7@1653|Corynebacteriaceae	201174|Actinobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
YHH1_k127_4320925_0	646529.Desaci_4611	8.918e-09	61.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,262K0@186807|Peptococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
YHH1_k127_437506_3	1117647.M5M_06395	1.266e-05	56.0	COG3509@1|root,COG3509@2|Bacteria,1R66H@1224|Proteobacteria,1SZAS@1236|Gammaproteobacteria,1J8CD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	PHB depolymerase family esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
YHH1_k127_437506_0	246194.CHY_1100	2.484e-171	565.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,42F6C@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YHH1_k127_437506_2	1232410.KI421420_gene3152	6.95e-06	52.0	COG0721@1|root,COG0721@2|Bacteria,1QE6H@1224|Proteobacteria,42VPR@68525|delta/epsilon subdivisions,2WRP0@28221|Deltaproteobacteria,43SNX@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Glu-tRNAGln amidotransferase C subunit	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
YHH1_k127_437506_1	1123371.ATXH01000006_gene873	1.661e-145	475.0	COG0154@1|root,COG0154@2|Bacteria,2GHH3@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH1_k127_4382196_0	517418.Ctha_2076	4.462e-05	58.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1FF5N@1090|Chlorobi	1090|Chlorobi	U	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4404718_0	744872.Spica_0889	3.119e-46	173.0	COG1373@1|root,COG1373@2|Bacteria,2J6SC@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_4404718_1	457398.HMPREF0326_02908	1.284e-13	72.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42R8B@68525|delta/epsilon subdivisions,2X5KI@28221|Deltaproteobacteria,2MGSH@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
YHH1_k127_4419807_0	1033730.CAHG01000014_gene1718	2.275e-66	230.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4DP2I@85009|Propionibacteriales	201174|Actinobacteria	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase,HTH_3
YHH1_k127_4419807_3	526218.Sterm_1173	9.42e-40	168.0	COG1198@1|root,COG1198@2|Bacteria,379NZ@32066|Fusobacteria	32066|Fusobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
YHH1_k127_4419807_5	1125725.HMPREF1325_2621	2.984e-25	111.0	COG0242@1|root,COG0242@2|Bacteria,2J7X0@203691|Spirochaetes	203691|Spirochaetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
YHH1_k127_4419807_2	324602.Caur_0033	1.339e-48	184.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi,3759R@32061|Chloroflexia	32061|Chloroflexia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YHH1_k127_4419807_1	867903.ThesuDRAFT_00243	7.499e-54	203.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WCJ6@538999|Clostridiales incertae sedis	186801|Clostridia	M	Domain present in PSD-95, Dlg, and ZO-1/2.	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
YHH1_k127_4419807_4	194439.CT1577	1.529e-32	133.0	COG0233@1|root,COG0233@2|Bacteria,1FDWC@1090|Chlorobi	1090|Chlorobi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
YHH1_k127_4424891_1	396595.TK90_1562	1.17e-19	93.0	COG0500@1|root,COG2226@2|Bacteria,1RG8C@1224|Proteobacteria,1SSHV@1236|Gammaproteobacteria,1X1GD@135613|Chromatiales	135613|Chromatiales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH1_k127_4424891_0	1499967.BAYZ01000086_gene5149	2.448e-39	161.0	COG0438@1|root,COG0438@2|Bacteria,2NR76@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_4435205_0	1191523.MROS_0428	1.786e-35	141.0	COG0566@1|root,COG0566@2|Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	2.1.1.185,2.1.1.34	ko:K00556,ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase
YHH1_k127_4469690_0	509191.AEDB02000081_gene2409	1.494e-99	346.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,3WGDE@541000|Ruminococcaceae	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
YHH1_k127_4469690_1	555088.DealDRAFT_2961	4.586e-32	127.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,42JNG@68298|Syntrophomonadaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YHH1_k127_4472422_1	314345.SPV1_12021	1.041e-16	89.0	COG1988@1|root,COG1988@2|Bacteria,1MZEI@1224|Proteobacteria	1224|Proteobacteria	NU	membrane-bound metal-dependent	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
YHH1_k127_4472422_0	1259795.ARJK01000004_gene1341	1.095e-102	362.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,42G7V@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,Peptidase_S8,SLH
YHH1_k127_4472422_2	156578.ATW7_10038	2.207e-09	71.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,PKD,Peptidase_S8
YHH1_k127_4482069_2	754027.HMPREF9554_02954	9.762e-42	168.0	COG0683@1|root,COG0683@2|Bacteria,2J62Q@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YHH1_k127_4482069_3	313628.LNTAR_08769	2.486e-06	59.0	COG1378@1|root,COG1378@2|Bacteria	2|Bacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_4482069_1	1121377.KB906399_gene1544	2.129e-60	217.0	COG0410@1|root,COG0410@2|Bacteria,1WJM5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
YHH1_k127_4482069_0	907348.TresaDRAFT_1483	1.509e-68	238.0	COG1373@1|root,COG1373@2|Bacteria,2J6SC@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_4534504_0	1123376.AUIU01000013_gene1878	9.397e-135	441.0	COG0542@1|root,COG0542@2|Bacteria,3J0AV@40117|Nitrospirae	40117|Nitrospirae	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH1_k127_4558209_1	682795.AciX8_0798	1.831e-06	56.0	COG1570@1|root,COG1570@2|Bacteria,3Y3DP@57723|Acidobacteria,2JIQN@204432|Acidobacteriia	204432|Acidobacteriia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
YHH1_k127_4558209_0	1121918.ARWE01000001_gene1199	7.699e-08	56.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,43U4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YHH1_k127_4595148_0	1367491.BN865_11150	9.178e-06	50.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2YNAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	amino acid abc transporter	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YHH1_k127_4595148_1	469371.Tbis_1469	1.06e-05	57.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4DZ5A@85010|Pseudonocardiales	201174|Actinobacteria	E	Receptor family ligand binding region	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YHH1_k127_4598749_2	765420.OSCT_0787	0.0008797	51.0	COG0553@1|root,COG0553@2|Bacteria,2G6I4@200795|Chloroflexi,376H9@32061|Chloroflexia	32061|Chloroflexia	KL	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2
YHH1_k127_4598749_0	525257.HMPREF0204_11338	6.616e-70	243.0	COG0270@1|root,COG0270@2|Bacteria,4P3NG@976|Bacteroidetes,1I91K@117743|Flavobacteriia	976|Bacteroidetes	L	DNA (cytosine-5-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4598749_1	1173029.JH980292_gene1875	4.569e-08	57.0	COG1403@1|root,COG1403@2|Bacteria,1G7VH@1117|Cyanobacteria,1HCI7@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_5
YHH1_k127_4599637_2	243265.plu2037	0.0006313	48.0	COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,1RPX9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	endonuclease I	endA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005576,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019439,GO:0034641,GO:0034655,GO:0042597,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	3.1.21.1	ko:K01150	-	-	-	-	ko00000,ko01000	-	-	-	Endonuclease_1
YHH1_k127_4599637_0	376619.FTL_1452	4.56e-20	93.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,460WG@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YHH1_k127_4599637_1	1209989.TepiRe1_2821	1.146e-18	91.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,42GRT@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
YHH1_k127_4614350_0	1089550.ATTH01000002_gene15	1.471e-32	132.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1FKET@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
YHH1_k127_4614350_1	161156.JQKW01000011_gene931	6.179e-06	55.0	COG2204@1|root,COG2204@2|Bacteria,2GH79@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_4633507_0	765952.PUV_22730	9.86e-173	560.0	COG0481@1|root,COG0481@2|Bacteria,2JFFF@204428|Chlamydiae	204428|Chlamydiae	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YHH1_k127_4686169_1	426716.JOAJ01000001_gene1286	0.0008264	43.0	COG0411@1|root,COG0411@2|Bacteria,2IGY0@201174|Actinobacteria,4FZE1@85025|Nocardiaceae	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
YHH1_k127_4686169_0	1266845.Q783_07540	1.32e-05	56.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,27F7P@186828|Carnobacteriaceae	91061|Bacilli	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YHH1_k127_4686415_1	272563.CD630_12560	6.095e-36	144.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,25QFE@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
YHH1_k127_4686415_0	649831.L083_3846	2.986e-36	143.0	COG1051@1|root,COG1051@2|Bacteria,2IIHF@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH1_k127_4686415_2	1033734.CAET01000018_gene693	1.438e-14	79.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,1ZIW7@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
YHH1_k127_4686415_3	1034808.GIG_02368	1.088e-12	72.0	COG0228@1|root,COG0228@2|Bacteria,3WTVG@544448|Tenericutes	544448|Tenericutes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
YHH1_k127_4686415_4	543734.LCABL_16150	0.0005303	44.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,3F3SS@33958|Lactobacillaceae	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
YHH1_k127_4689728_0	1120972.AUMH01000022_gene599	2.225e-96	323.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,2787C@186823|Alicyclobacillaceae	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10965	ATP-synt_ab,ATP-synt_ab_N
YHH1_k127_4689728_1	867903.ThesuDRAFT_02401	1.745e-31	130.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3WCHP@538999|Clostridiales incertae sedis	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
YHH1_k127_4707083_1	351160.RCIX2387	1.648e-46	180.0	COG0651@1|root,arCOG01537@2157|Archaea,2Y85B@28890|Euryarchaeota,2NAGR@224756|Methanomicrobia	224756|Methanomicrobia	C	plastoquinone (Complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
YHH1_k127_4707083_0	330214.NIDE4264	4.941e-75	263.0	COG0650@1|root,COG0650@2|Bacteria,3J0RR@40117|Nitrospirae	40117|Nitrospirae	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
YHH1_k127_4707083_3	395494.Galf_2382	2.935e-14	81.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2VJTI@28216|Betaproteobacteria,44W5S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	hydrogenase 4 membrane	hyfE	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
YHH1_k127_4707083_2	1005994.GTGU_02552	9.488e-29	122.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,1RPB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone	hyfF	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	iECIAI39_1322.ECIAI39_2625,iZ_1308.Z3746	Proton_antipo_M,Proton_antipo_N
YHH1_k127_4721840_0	1122605.KB893644_gene1305	3.175e-53	209.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,1IPF7@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH1_k127_4749185_0	1042163.BRLA_c046450	4.212e-114	379.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,26RK6@186822|Paenibacillaceae	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YHH1_k127_4749185_1	1112204.GPOL_c20810	4.885e-28	122.0	COG0561@1|root,COG0561@2|Bacteria,2HZD0@201174|Actinobacteria,4GBZ3@85026|Gordoniaceae	201174|Actinobacteria	S	Eukaryotic phosphomannomutase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,PMM
YHH1_k127_4756644_0	1536774.H70357_19855	2.114e-06	51.0	2DNC9@1|root,32WR7@2|Bacteria,1VDWX@1239|Firmicutes,4HN69@91061|Bacilli,26ZHV@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_4778315_1	314230.DSM3645_20532	1.098e-16	82.0	COG1278@1|root,COG1278@2|Bacteria,2J13Y@203682|Planctomycetes	203682|Planctomycetes	K	COG1278 Cold shock	-	-	-	-	-	-	-	-	-	-	-	-	CSD
YHH1_k127_4778315_0	858215.Thexy_0673	3.054e-54	209.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,42F7H@68295|Thermoanaerobacterales	186801|Clostridia	S	pfam abc	-	-	-	ko:K06158,ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000,ko03012	3.A.1.121	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH1_k127_4778315_2	1158345.JNLL01000001_gene971	9.942e-05	49.0	COG0188@1|root,COG1372@1|root,COG0188@2|Bacteria,COG1372@2|Bacteria,2G3MH@200783|Aquificae	200783|Aquificae	L	DNA gyrase topoisomerase IV, subunit A	gyrA	GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV,Intein_splicing,LAGLIDADG_3
YHH1_k127_483895_2	562981.HMPREF0428_00271	4.449e-21	94.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,3WE4C@539002|Bacillales incertae sedis	91061|Bacilli	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
YHH1_k127_483895_0	67593.Physo127942	1.12e-73	263.0	COG0042@1|root,KOG2335@2759|Eukaryota,3QEGX@4776|Peronosporales	4776|Peronosporales	J	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs	-	-	-	-	-	-	-	-	-	-	-	-	Dus
YHH1_k127_483895_3	572477.Alvin_1775	1.089e-05	55.0	2CI2Z@1|root,348DB@2|Bacteria,1P2GJ@1224|Proteobacteria,1SSVZ@1236|Gammaproteobacteria,1X1B1@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_483895_1	1178482.BJB45_06670	8.44e-56	204.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1XHEP@135619|Oceanospirillales	135619|Oceanospirillales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
YHH1_k127_4848860_2	545276.KB898724_gene2101	0.0003366	51.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1WWER@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
YHH1_k127_4848860_0	411483.FAEPRAA2165_01884	1.881e-27	116.0	2CDFK@1|root,2Z8BH@2|Bacteria,1V43D@1239|Firmicutes,24KG0@186801|Clostridia,3WKBM@541000|Ruminococcaceae	186801|Clostridia	H	DNA N-6-adenine-methyltransferase (Dam)	-	-	-	-	-	-	-	-	-	-	-	-	Dam
YHH1_k127_4878620_0	665571.STHERM_c15920	8.924e-176	583.0	COG0060@1|root,COG0060@2|Bacteria,2J57V@203691|Spirochaetes	203691|Spirochaetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YHH1_k127_4878620_1	1173263.Syn7502_00143	1.174e-07	59.0	COG2402@1|root,COG2402@2|Bacteria,1G7JM@1117|Cyanobacteria	1117|Cyanobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH1_k127_4878620_2	453591.Igni_0928	0.0004317	43.0	COG0018@1|root,arCOG00487@2157|Archaea,2XPXC@28889|Crenarchaeota	28889|Crenarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YHH1_k127_4900663_0	649761.HMPREF0973_02548	2.055e-110	369.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,2FNF4@200643|Bacteroidia	976|Bacteroidetes	L	ATPase (AAA	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
YHH1_k127_4900663_1	1312959.KI914681_gene2003	6.609e-08	57.0	COG5611@1|root,COG5611@2|Bacteria,2GUMH@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH1_k127_490261_0	1047013.AQSP01000123_gene1545	1.586e-55	215.0	COG2373@1|root,COG2373@2|Bacteria,2NQA2@2323|unclassified Bacteria	2|Bacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1,Thiol-ester_cl
YHH1_k127_4905057_0	1120953.AUBH01000005_gene2269	3.754e-12	77.0	COG1112@1|root,COG1112@2|Bacteria,1MWMG@1224|Proteobacteria,1RPEF@1236|Gammaproteobacteria,468CV@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF559
YHH1_k127_4986333_0	765869.BDW_09095	2.244e-63	231.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2MSU0@213481|Bdellovibrionales,2WIP1@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
YHH1_k127_4998141_1	1121413.JMKT01000003_gene176	1.573e-13	74.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42U5G@68525|delta/epsilon subdivisions,2WQ28@28221|Deltaproteobacteria,2MF1X@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
YHH1_k127_4998141_0	383372.Rcas_4321	2.259e-58	207.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi,37569@32061|Chloroflexia	32061|Chloroflexia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
YHH1_k127_4998141_2	891968.Anamo_0201	1.493e-07	54.0	COG0690@1|root,COG0690@2|Bacteria,3TBK4@508458|Synergistetes	508458|Synergistetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
YHH1_k127_5002155_0	351160.RCIX1478	1.289e-44	168.0	arCOG02140@1|root,arCOG02140@2157|Archaea,2Y5Y2@28890|Euryarchaeota,2NBBF@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5002155_1	269797.Mbar_A2727	6.871e-21	98.0	arCOG02138@1|root,arCOG02138@2157|Archaea,2Y150@28890|Euryarchaeota,2NA0H@224756|Methanomicrobia	224756|Methanomicrobia	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5008247_0	342113.DM82_112	5.336e-74	280.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,1KEFQ@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
YHH1_k127_5020800_0	1057002.KB905370_gene1555	4.626e-11	77.0	2ESGW@1|root,33K1K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
YHH1_k127_5059089_3	935557.ATYB01000014_gene1436	0.0005623	44.0	COG3325@1|root,COG3325@2|Bacteria,1RDYE@1224|Proteobacteria,2VEFV@28211|Alphaproteobacteria,4BIZZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
YHH1_k127_5059089_1	1089551.KE386572_gene4236	0.0001577	53.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2TSEB@28211|Alphaproteobacteria,4BQ0H@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	lpxH	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
YHH1_k127_5059089_2	1235800.C819_04338	0.0003267	46.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH1_k127_5067267_0	237368.SCABRO_01703	4.527e-32	136.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,2IZ3Q@203682|Planctomycetes	203682|Planctomycetes	L	COG0084 Mg-dependent DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
YHH1_k127_507111_0	243231.GSU0117	8.274e-131	426.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria,43TA7@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM aminotransferase, class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_5086877_2	1410618.JNKI01000005_gene2317	2.155e-31	132.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4H27I@909932|Negativicutes	909932|Negativicutes	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
YHH1_k127_5086877_4	283942.IL2634	3.96e-20	92.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria	1224|Proteobacteria	L	PFAM Excinuclease ABC, C subunit domain protein	yhbQ	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH1_k127_5086877_1	929713.NIASO_19615	2.146e-66	233.0	COG2085@1|root,COG2085@2|Bacteria,4NPSZ@976|Bacteroidetes,1IYAV@117747|Sphingobacteriia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
YHH1_k127_5086877_3	1408304.JAHA01000008_gene1928	1.715e-27	121.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,4BZ96@830|Butyrivibrio	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
YHH1_k127_5086877_0	1280949.HAD_14577	1.986e-94	328.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,43WPJ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	COG0513 Superfamily II DNA and RNA helicases	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
YHH1_k127_5101656_0	479436.Vpar_1520	2.283e-30	128.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H207@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding protein, transpeptidase domain protein	ftsI	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
YHH1_k127_512975_0	1201290.M902_0225	9.32e-05	56.0	COG2911@1|root,COG3209@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2WRDH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	cell wall surface anchor family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
YHH1_k127_5148735_2	1335760.ASTG01000029_gene2356	1.544e-08	65.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K2DF@204457|Sphingomonadales	204457|Sphingomonadales	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
YHH1_k127_5148735_0	644966.Tmar_0214	6.194e-52	203.0	COG0421@1|root,COG0421@2|Bacteria,1UI4A@1239|Firmicutes,25GIE@186801|Clostridia	186801|Clostridia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YHH1_k127_5148735_1	1459636.NTE_03024	4.572e-22	102.0	COG1430@1|root,arCOG03116@2157|Archaea	2157|Archaea	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
YHH1_k127_520258_1	760568.Desku_2738	7.515e-26	121.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,26014@186807|Peptococcaceae	186801|Clostridia	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
YHH1_k127_520258_0	1206730.BAGA01000058_gene2605	2.83e-32	131.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4FX7S@85025|Nocardiaceae	201174|Actinobacteria	GL	Reverse transcriptase-like	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
YHH1_k127_522521_0	439235.Dalk_2354	7.417e-14	74.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,42PSQ@68525|delta/epsilon subdivisions,2WKDY@28221|Deltaproteobacteria,2MK85@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
YHH1_k127_522521_1	679192.HMPREF9013_0024	1.911e-13	74.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,3VRKA@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NifU
YHH1_k127_522521_2	1469607.KK073769_gene5847	1.633e-12	70.0	COG3905@1|root,COG3905@2|Bacteria,1G9E3@1117|Cyanobacteria,1HQ5Z@1161|Nostocales	1117|Cyanobacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
YHH1_k127_5225665_0	1232428.CAVO010000031_gene1593	5.001e-13	74.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4H41I@909932|Negativicutes	909932|Negativicutes	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
YHH1_k127_5225665_1	1232410.KI421421_gene3591	1.315e-12	69.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,43SM8@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
YHH1_k127_5226451_0	518766.Rmar_0977	3.198e-87	310.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1FJ4P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
YHH1_k127_5247202_0	156889.Mmc1_3729	3.99e-90	315.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
YHH1_k127_5247202_1	316274.Haur_1712	1.988e-25	108.0	COG0221@1|root,COG0221@2|Bacteria,2G6T4@200795|Chloroflexi,375J0@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
YHH1_k127_5303672_0	1121360.AUAQ01000011_gene360	4.938e-12	72.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,22N7F@1653|Corynebacteriaceae	201174|Actinobacteria	P	Belongs to the Fur family	furB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH1_k127_5310279_0	702438.HMPREF9431_00782	1.189e-39	157.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH1_k127_5331505_0	436308.Nmar_1073	1.163e-07	65.0	COG3794@1|root,arCOG05978@1|root,arCOG07813@1|root,arCOG02926@2157|Archaea,arCOG05978@2157|Archaea,arCOG07813@2157|Archaea	2157|Archaea	C	LamG domain protein jellyroll fold domain protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	Copper-bind,GSDH,Laminin_G_3,ThuA,fn3
YHH1_k127_5361188_0	1122238.AULR01000002_gene323	1.317e-35	144.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4FKKW@85023|Microbacteriaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
YHH1_k127_5361188_1	232348.ADXL01000060_gene2452	3.31e-25	114.0	COG0793@1|root,COG0793@2|Bacteria,1G1YJ@1117|Cyanobacteria,1GYEZ@1129|Synechococcus	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
YHH1_k127_5410542_2	1343739.PAP_08740	1.601e-12	78.0	COG5274@1|root,2N57D@2157|Archaea,2Y48S@28890|Euryarchaeota,2455C@183968|Thermococci	183968|Thermococci	CI	Cytochrome b5-like Heme/Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
YHH1_k127_5410542_1	4558.Sb01g007770.1	4.648e-14	83.0	COG5274@1|root,KOG0537@2759|Eukaryota,37VH4@33090|Viridiplantae,3GJH6@35493|Streptophyta,3KZXG@4447|Liliopsida,3IH8R@38820|Poales	35493|Streptophyta	C	Belongs to the cytochrome b5 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009526,GO:0009527,GO:0009536,GO:0009707,GO:0009941,GO:0010319,GO:0016020,GO:0019867,GO:0031090,GO:0031967,GO:0031968,GO:0031969,GO:0031975,GO:0042170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0098588,GO:0098805	-	-	-	-	-	-	-	-	-	-	Cyt-b5
YHH1_k127_5410542_0	1123234.AUKI01000016_gene3137	2.376e-62	231.0	COG4097@1|root,COG4097@2|Bacteria,4NQ29@976|Bacteroidetes,1I334@117743|Flavobacteriia	976|Bacteroidetes	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
YHH1_k127_5429973_1	796945.HMPREF1145_1758	0.0003276	44.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,2492D@186801|Clostridia,2PRUX@265975|Oribacterium	186801|Clostridia	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YHH1_k127_5429973_0	1313265.JNIE01000002_gene867	1.359e-109	370.0	COG0143@1|root,COG0143@2|Bacteria,2G3J0@200783|Aquificae	200783|Aquificae	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
YHH1_k127_5441973_0	1123274.KB899436_gene1284	7.854e-06	58.0	COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	tccC1	-	-	ko:K09800,ko:K11021,ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001,ko02000,ko02042	-	-	-	RHS_repeat
YHH1_k127_5511929_0	479434.Sthe_1913	1.225e-31	138.0	COG1664@1|root,COG1664@2|Bacteria,2G79N@200795|Chloroflexi,27Y9Z@189775|Thermomicrobia	189775|Thermomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_551382_0	1265505.ATUG01000001_gene4101	2.156e-37	154.0	COG3209@1|root,COG3266@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria,1MVV1@1224|Proteobacteria,42P9N@68525|delta/epsilon subdivisions,2WJSQ@28221|Deltaproteobacteria,2MIDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM RHS repeat-associated core	-	-	-	-	-	-	-	-	-	-	-	-	AHH,RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
YHH1_k127_5535295_0	1047013.AQSP01000127_gene472	4.918e-80	275.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BPD_transp_2
YHH1_k127_5535295_1	580340.Tlie_1018	2.005e-28	129.0	COG0683@1|root,COG0683@2|Bacteria,3T9QY@508458|Synergistetes	508458|Synergistetes	E	PFAM Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YHH1_k127_5535295_2	1443665.JACA01000026_gene3487	3.317e-26	109.0	COG1502@1|root,COG1502@2|Bacteria,4NMXS@976|Bacteroidetes,1I2ID@117743|Flavobacteriia	976|Bacteroidetes	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
YHH1_k127_555040_0	4572.TRIUR3_34777-P1	1.597e-61	219.0	COG1418@1|root,2QSR7@2759|Eukaryota,37SE2@33090|Viridiplantae,3G8YY@35493|Streptophyta,3KQSN@4447|Liliopsida,3I3N1@38820|Poales	35493|Streptophyta	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
YHH1_k127_555040_1	745310.G432_11080	1.829e-30	127.0	2CFS3@1|root,32S2D@2|Bacteria,1N23S@1224|Proteobacteria,2U9XJ@28211|Alphaproteobacteria,2K236@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_556581_0	123214.PERMA_1332	1.065e-68	236.0	COG0178@1|root,COG0178@2|Bacteria,2G3KE@200783|Aquificae	200783|Aquificae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH1_k127_5568480_0	873517.HMPREF1977_2190	2.403e-117	385.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1HWQR@117743|Flavobacteriia,1ERE0@1016|Capnocytophaga	976|Bacteroidetes	M	Psort location Cytoplasmic, score 8.96	rfaD	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH1_k127_5614455_0	91464.S7335_3159	1.293e-58	211.0	COG0441@1|root,COG0441@2|Bacteria,1G1E9@1117|Cyanobacteria,1GYZR@1129|Synechococcus	1117|Cyanobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iJN678.thrS	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
YHH1_k127_5625097_0	1121428.DESHY_150015___1	5.783e-84	294.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,26070@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH1_k127_5625097_1	1116232.AHBF01000016_gene3599	1.424e-21	104.0	COG0739@1|root,COG0739@2|Bacteria,2GU2Q@201174|Actinobacteria	201174|Actinobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH1_k127_5625097_2	746697.Aeqsu_2014	1.542e-05	50.0	2E4KV@1|root,32ZFU@2|Bacteria,4PN8Z@976|Bacteroidetes,1IMXX@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
YHH1_k127_5693492_1	649747.HMPREF0083_06163	0.0001502	55.0	COG1657@1|root,COG1657@2|Bacteria,1UZVS@1239|Firmicutes,4HDE7@91061|Bacilli	91061|Bacilli	I	Alpha amylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Gram_pos_anchor,Prenyltrans,SLH,SQHop_cyclase_C
YHH1_k127_5693492_0	1208323.B30_10290	6.107e-06	54.0	COG1378@1|root,COG1378@2|Bacteria,1PZ3N@1224|Proteobacteria,2UHQ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_5743775_3	1203611.KB894544_gene2213	3.595e-45	181.0	COG0389@1|root,COG0389@2|Bacteria,4NGPH@976|Bacteroidetes,2FPC7@200643|Bacteroidia,22U0Y@171550|Rikenellaceae	976|Bacteroidetes	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
YHH1_k127_5743775_0	224325.AF_0817	3.564e-113	392.0	COG1948@1|root,arCOG02284@2157|Archaea,2XT7B@28890|Euryarchaeota,245S0@183980|Archaeoglobi	183980|Archaeoglobi	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
YHH1_k127_5743775_1	547042.BACCOPRO_00873	2.225e-101	336.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,2FM57@200643|Bacteroidia,4AMXR@815|Bacteroidaceae	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH1_k127_5743775_4	1384065.JAGS01000001_gene1094	4.074e-16	86.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3WJK5@541000|Ruminococcaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YHH1_k127_5743775_2	1382306.JNIM01000001_gene1384	3.409e-96	319.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YHH1_k127_5755670_1	585.DR95_2004	1.979e-08	65.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,3Z11G@583|Proteus	1236|Gammaproteobacteria	M	rod shape-determining protein MreC	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
YHH1_k127_5755670_0	370438.PTH_0817	6.96e-106	353.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,260KS@186807|Peptococcaceae	186801|Clostridia	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH1_k127_5770658_11	1547437.LL06_20930	0.0003809	48.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,43I0U@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
YHH1_k127_5770658_3	574375.BAGA_04450	1.237e-37	159.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus	91061|Bacilli	T	Signal transduction histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
YHH1_k127_5770658_5	621372.ACIH01000251_gene3585	3.638e-18	89.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4HEGD@91061|Bacilli,26TR8@186822|Paenibacillaceae	91061|Bacilli	T	Transcriptional regulator	mprA1	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_5770658_9	765913.ThidrDRAFT_1421	1.214e-07	55.0	2ES8A@1|root,33JSY@2|Bacteria,1NHTH@1224|Proteobacteria,1SHN8@1236|Gammaproteobacteria,1WZPR@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5770658_4	1462527.CCDM010000002_gene634	1.821e-18	100.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TQ85@1239|Firmicutes,4HAC0@91061|Bacilli,23J0C@182709|Oceanobacillus	91061|Bacilli	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
YHH1_k127_5770658_0	1120973.AQXL01000114_gene699	3.865e-103	346.0	COG3387@1|root,COG3387@2|Bacteria,1V01W@1239|Firmicutes,4HCVG@91061|Bacilli	91061|Bacilli	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
YHH1_k127_5770658_7	1120985.AUMI01000011_gene541	4.009e-09	65.0	COG3271@1|root,COG3271@2|Bacteria,1VAKE@1239|Firmicutes,4H81P@909932|Negativicutes	909932|Negativicutes	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5770658_10	459495.SPLC1_S412040	1.373e-07	56.0	COG3041@1|root,COG3041@2|Bacteria,1G7V7@1117|Cyanobacteria,1HC9D@1150|Oscillatoriales	1117|Cyanobacteria	S	Bacterial toxin of type II toxin-antitoxin system, YafQ	-	-	-	-	-	-	-	-	-	-	-	-	YafQ_toxin
YHH1_k127_5770658_6	1042163.BRLA_c008440	1.032e-11	78.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,4HG99@91061|Bacilli,26RNQ@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	hlyD3	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH1_k127_5770658_1	521003.COLINT_02534	1.24e-67	237.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4CYFZ@84998|Coriobacteriia	84998|Coriobacteriia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_5770658_2	765420.OSCT_0805	8.501e-40	160.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi,37660@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_5778448_0	479434.Sthe_2499	8.581e-47	178.0	29JD5@1|root,306AN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5830958_0	525373.HMPREF0766_12813	2.455e-125	420.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1IPGD@117747|Sphingobacteriia	976|Bacteroidetes	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
YHH1_k127_5830958_1	391623.TERMP_01411	1.032e-78	267.0	COG0450@1|root,arCOG00312@2157|Archaea,2XYCY@28890|Euryarchaeota,243M2@183968|Thermococci	183968|Thermococci	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
YHH1_k127_5830958_2	387093.SUN_0978	9.153e-60	213.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42TAC@68525|delta/epsilon subdivisions,2YRI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG2518 Protein-L-isoaspartate carboxylmethyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
YHH1_k127_5830958_3	1123320.KB889607_gene9530	7.926e-22	105.0	COG2310@1|root,COG2340@1|root,COG2310@2|Bacteria,COG2340@2|Bacteria,2GNN0@201174|Actinobacteria	201174|Actinobacteria	T	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,TerD
YHH1_k127_5840345_5	888055.HMPREF9015_00902	3.984e-07	57.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_1,TPR_10,TPR_2,TPR_8
YHH1_k127_5840345_3	1121272.KB903290_gene4634	1.731e-44	175.0	COG0697@1|root,COG0697@2|Bacteria,2IH82@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH1_k127_5840345_1	983545.Glaag_1970	4.916e-59	220.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1FK@1236|Gammaproteobacteria,46D7C@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
YHH1_k127_5840345_4	1279038.KB907337_gene547	3.689e-25	116.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2TUPZ@28211|Alphaproteobacteria,2JQS5@204441|Rhodospirillales	204441|Rhodospirillales	E	N-formylglutamate amidohydrolase	-	-	3.5.1.68	ko:K01458	ko00340,ko00630,map00340,map00630	-	R00525	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	FGase
YHH1_k127_5840345_0	1123325.JHUV01000008_gene765	5.177e-70	247.0	COG2404@1|root,COG2404@2|Bacteria,2G567@200783|Aquificae	200783|Aquificae	S	phosphoesterase, dhha1	-	-	-	-	-	-	-	-	-	-	-	-	DHHA1
YHH1_k127_5840345_2	290317.Cpha266_2157	7.164e-53	196.0	COG1752@1|root,COG1752@2|Bacteria,1FDF3@1090|Chlorobi	1090|Chlorobi	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
YHH1_k127_5847038_4	1423724.BAMM01000042_gene2171	0.0003245	43.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5847038_3	1155714.KB891996_gene3504	7.441e-19	96.0	COG3415@1|root,COG3415@2|Bacteria,2HK0D@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Terminase_5
YHH1_k127_5847038_1	243231.GSU2323	7.414e-78	268.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,42R9G@68525|delta/epsilon subdivisions,2WMTN@28221|Deltaproteobacteria,43TRU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
YHH1_k127_5847038_2	666684.AfiDRAFT_2817	5.625e-34	136.0	COG4852@1|root,COG4852@2|Bacteria,1MZHP@1224|Proteobacteria,2UBSF@28211|Alphaproteobacteria,3K0TU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
YHH1_k127_5847038_0	1121024.AUCD01000032_gene1911	8.477e-84	282.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,27FFZ@186828|Carnobacteriaceae	91061|Bacilli	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YHH1_k127_5867481_0	1303518.CCALI_00921	8.073e-114	375.0	COG0556@1|root,COG0556@2|Bacteria	2|Bacteria	L	nucleotide-excision repair	uvrB	-	-	ko:K03702,ko:K08999	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH1_k127_5881629_0	563192.HMPREF0179_03201	1.859e-152	492.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
YHH1_k127_5881629_1	866536.Belba_1559	6.749e-103	349.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
YHH1_k127_5881629_2	313590.MED134_13511	0.0001496	44.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1HXC3@117743|Flavobacteriia,37EZ3@326319|Dokdonia	976|Bacteroidetes	U	SecA preprotein cross-linking domain	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH1_k127_5886814_1	926569.ANT_26810	6.823e-12	71.0	COG2836@1|root,COG4633@1|root,COG2836@2|Bacteria,COG4633@2|Bacteria	2|Bacteria	K	Biogenesis protein	silP	-	1.9.3.1,3.6.3.54	ko:K02275,ko:K09792,ko:K17686	ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016	M00155	R00081,R00086	RC00002,RC00016	ko00000,ko00001,ko00002,ko01000	3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,DsbD_2,Ferric_reduct,HMA
YHH1_k127_5886814_0	1304865.JAGF01000001_gene2536	5.027e-34	139.0	COG2608@1|root,COG2836@1|root,COG4633@1|root,COG2608@2|Bacteria,COG2836@2|Bacteria,COG4633@2|Bacteria,2IETB@201174|Actinobacteria	201174|Actinobacteria	P	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
YHH1_k127_5901075_0	243231.GSU3207	9.008e-119	396.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,43T5X@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
YHH1_k127_5913012_0	761193.Runsl_0545	1.522e-57	204.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,47QQP@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
YHH1_k127_5930668_0	103690.17130869	2.601e-97	328.0	COG0189@1|root,COG0189@2|Bacteria,1GBE8@1117|Cyanobacteria,1HJ35@1161|Nostocales	1117|Cyanobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	RimK
YHH1_k127_5930668_1	558169.AGAV01000017_gene1133	4.958e-28	121.0	COG1738@1|root,COG1738@2|Bacteria,1TSAY@1239|Firmicutes,4HB9T@91061|Bacilli	91061|Bacilli	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	yhhQ_2	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
YHH1_k127_5958899_0	1392501.JIAC01000001_gene1028	2.034e-32	131.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4H4X8@909932|Negativicutes	909932|Negativicutes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
YHH1_k127_5958899_1	1111479.AXAR01000008_gene2369	7.041e-21	98.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,278CE@186823|Alicyclobacillaceae	91061|Bacilli	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
YHH1_k127_5990071_0	383372.Rcas_1598	6.629e-68	243.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi,374ZB@32061|Chloroflexia	32061|Chloroflexia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH1_k127_6050569_1	1033739.CAEU01000018_gene2415	1.749e-06	55.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,4HEPK@91061|Bacilli,26FB3@186818|Planococcaceae	91061|Bacilli	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
YHH1_k127_6050569_0	99598.Cal7507_5074	1.385e-88	302.0	COG0606@1|root,COG0606@2|Bacteria,1G0K1@1117|Cyanobacteria,1HIXF@1161|Nostocales	1117|Cyanobacteria	O	PFAM Magnesium chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH1_k127_6062618_0	1121373.KB903665_gene3086	1.997e-21	108.0	COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,47MVB@768503|Cytophagia	976|Bacteroidetes	D	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
YHH1_k127_6062618_1	694429.Pyrfu_0610	1.278e-05	53.0	COG2402@1|root,arCOG04502@2157|Archaea,2XSKX@28889|Crenarchaeota	28889|Crenarchaeota	V	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
YHH1_k127_6066678_1	65393.PCC7424_0597	1.916e-08	67.0	COG0823@1|root,COG5276@1|root,COG0823@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	3.4.24.40	ko:K01406,ko:K03641,ko:K21449	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2,2.C.1.2	-	-	DUF1566,F5_F8_type_C,PD40
YHH1_k127_6066678_2	1173020.Cha6605_4255	1.998e-07	56.0	COG2336@1|root,COG2336@2|Bacteria,1G88T@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM SpoVT AbrB like domain	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH1_k127_6066678_0	471870.BACINT_00453	2.047e-23	103.0	COG2337@1|root,COG2337@2|Bacteria,4NQA9@976|Bacteroidetes,2FU6W@200643|Bacteroidia,4ATT6@815|Bacteroidaceae	976|Bacteroidetes	L	Toxic component of a toxin-antitoxin (TA) module	mazF	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH1_k127_6082222_1	935948.KE386493_gene2334	0.0001539	53.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,24948@186801|Clostridia,42ERM@68295|Thermoanaerobacterales	186801|Clostridia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
YHH1_k127_6082222_0	1501391.LG35_05820	3.016e-15	79.0	COG1238@1|root,COG1238@2|Bacteria,4PIJW@976|Bacteroidetes,2G1VB@200643|Bacteroidia,22V72@171550|Rikenellaceae	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH1_k127_6083666_1	386456.JQKN01000006_gene1260	9.115e-14	76.0	COG1669@1|root,arCOG01206@2157|Archaea,2Y03V@28890|Euryarchaeota	28890|Euryarchaeota	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
YHH1_k127_6083666_0	395961.Cyan7425_1935	5.085e-17	85.0	COG2361@1|root,COG2361@2|Bacteria,1G980@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
YHH1_k127_6130895_1	1123274.KB899411_gene3072	3.726e-05	47.0	COG1378@1|root,COG1378@2|Bacteria	2|Bacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_6130895_0	340177.Cag_1196	3.091e-262	842.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
YHH1_k127_6134218_0	1158345.JNLL01000001_gene686	8.619e-26	110.0	COG2445@1|root,COG2445@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
YHH1_k127_6134218_1	504728.K649_04105	5.179e-07	59.0	COG1669@1|root,COG1669@2|Bacteria,1WK3Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH1_k127_6150928_0	869209.Tresu_1584	1.292e-204	664.0	COG0653@1|root,COG0653@2|Bacteria,2J5UR@203691|Spirochaetes	203691|Spirochaetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH1_k127_6151409_0	1123376.AUIU01000011_gene806	2.517e-72	260.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
YHH1_k127_616444_0	649761.HMPREF0973_02548	2.634e-46	170.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,2FNF4@200643|Bacteroidia	976|Bacteroidetes	L	ATPase (AAA	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
YHH1_k127_616444_2	552811.Dehly_1446	4.599e-08	63.0	COG2002@1|root,COG2002@2|Bacteria,2G9HR@200795|Chloroflexi	200795|Chloroflexi	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
YHH1_k127_616444_1	234267.Acid_4367	1.017e-14	76.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin,YafQ_toxin
YHH1_k127_617906_2	479432.Sros_5843	6.382e-10	71.0	COG1522@1|root,COG1522@2|Bacteria,2GK3G@201174|Actinobacteria,4EIHN@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	lrp_3	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
YHH1_k127_617906_1	13035.Dacsa_1361	1.213e-15	79.0	COG3041@1|root,COG3041@2|Bacteria,1G7V7@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Plasmid maintenance system killer protein	-	-	-	-	-	-	-	-	-	-	-	-	YafQ_toxin
YHH1_k127_617906_0	546274.EIKCOROL_01441	2.434e-58	212.0	COG2801@1|root,COG2801@2|Bacteria,1MWNX@1224|Proteobacteria,2VN7F@28216|Betaproteobacteria,2KSBP@206351|Neisseriales	206351|Neisseriales	L	Integrase core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH1_k127_617995_1	1386969.AWTB01000117_gene154	0.0001814	51.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4GCPJ@85026|Gordoniaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	pimB	GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_617995_0	521045.Kole_0088	9.666e-41	171.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
YHH1_k127_6228283_1	756499.Desde_3271	1.925e-07	57.0	COG1708@1|root,COG1708@2|Bacteria,1VJJK@1239|Firmicutes,24RYH@186801|Clostridia,262RB@186807|Peptococcaceae	186801|Clostridia	L	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH1_k127_6228283_0	472759.Nhal_0317	2.288e-15	78.0	COG3668@1|root,COG3668@2|Bacteria,1N7G9@1224|Proteobacteria,1SBAB@1236|Gammaproteobacteria,1X1JR@135613|Chromatiales	135613|Chromatiales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH1_k127_6228283_2	314275.MADE_1018045	2.05e-05	50.0	COG3905@1|root,COG3905@2|Bacteria,1NHN3@1224|Proteobacteria,1SGV1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
YHH1_k127_6228283_3	572478.Vdis_1078	4.545e-05	51.0	COG2445@1|root,arCOG02112@2157|Archaea,2XS0A@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function DUF86	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	DUF86,NTP_transf_2
YHH1_k127_6249758_0	1121403.AUCV01000010_gene1423	2.851e-98	331.0	COG5433@1|root,COG5433@2|Bacteria,1MXI8@1224|Proteobacteria,42WFU@68525|delta/epsilon subdivisions,2WS4T@28221|Deltaproteobacteria,2MKX1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Pfam Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH1_k127_6260317_0	935837.JAEK01000015_gene5018	2.229e-10	68.0	COG0125@1|root,COG0125@2|Bacteria,1UIWQ@1239|Firmicutes,4ISUX@91061|Bacilli,1ZFMN@1386|Bacillus	91061|Bacilli	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
YHH1_k127_6262344_0	697281.Mahau_0398	4.076e-135	441.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,42G6T@68295|Thermoanaerobacterales	186801|Clostridia	KL	SMART DEAD-like helicase	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
YHH1_k127_6262344_1	1121346.KB899816_gene3255	2.917e-17	83.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,26QSY@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YHH1_k127_6302174_0	159087.Daro_0530	9.834e-71	254.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,2KUA8@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YHH1_k127_6314292_1	1042376.AFPK01000029_gene1558	1.657e-16	84.0	COG0745@1|root,COG0745@2|Bacteria,4PI9H@976|Bacteroidetes,1ICB1@117743|Flavobacteriia,407AM@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH1_k127_6314292_0	1122143.AUEG01000012_gene1720	1.256e-43	171.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,27G0D@186828|Carnobacteriaceae	91061|Bacilli	T	Single Cache-like	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like
YHH1_k127_6351185_1	690850.Desaf_1300	1.126e-37	149.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2M8EC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase domain protein	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
YHH1_k127_6351185_0	882083.SacmaDRAFT_5112	5.017e-91	314.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4DYW0@85010|Pseudonocardiales	201174|Actinobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YHH1_k127_637124_0	1047013.AQSP01000123_gene1545	2.204e-30	132.0	COG2373@1|root,COG2373@2|Bacteria,2NQA2@2323|unclassified Bacteria	2|Bacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1,Thiol-ester_cl
YHH1_k127_6429190_2	644801.Psest_3398	1.335e-45	168.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1Z2VF@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
YHH1_k127_6429190_4	234267.Acid_4417	2.445e-20	95.0	COG5586@1|root,COG5586@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2293
YHH1_k127_6429190_3	1229204.AMYY01000001_gene2861	6.989e-30	121.0	COG4430@1|root,COG4430@2|Bacteria,1RGC9@1224|Proteobacteria,2VGQ2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
YHH1_k127_6429190_0	485913.Krac_2142	1.087e-92	316.0	COG1619@1|root,COG1619@2|Bacteria	2|Bacteria	V	carboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
YHH1_k127_6429190_5	641143.HMPREF9331_00127	8.793e-19	91.0	2EN6U@1|root,315BM@2|Bacteria,4PBSN@976|Bacteroidetes,1I9B0@117743|Flavobacteriia,1ETDB@1016|Capnocytophaga	976|Bacteroidetes	S	STAS-like domain of unknown function (DUF4325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4325
YHH1_k127_6429190_1	1121896.JMLU01000032_gene867	1.112e-57	214.0	2E4H7@1|root,32ZCB@2|Bacteria,4NICA@976|Bacteroidetes,1IE34@117743|Flavobacteriia,2NZRQ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6493445_0	1128421.JAGA01000002_gene1806	1.673e-107	362.0	COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YHH1_k127_6493445_1	316274.Haur_0408	8.727e-25	108.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi,37783@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YHH1_k127_6505157_0	742738.HMPREF9460_02550	6.57e-115	387.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,267P4@186813|unclassified Clostridiales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YHH1_k127_6505157_1	1121930.AQXG01000014_gene350	7.352e-13	81.0	COG1404@1|root,COG2356@1|root,COG3291@1|root,COG1404@2|Bacteria,COG2356@2|Bacteria,COG3291@2|Bacteria,4PI1X@976|Bacteroidetes,1IXYZ@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1
YHH1_k127_6506619_0	1444309.JAQG01000013_gene1891	6.029e-152	495.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,26R74@186822|Paenibacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH1_k127_6511664_0	909663.KI867150_gene818	1.619e-05	56.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
YHH1_k127_6511664_1	531844.FIC_01098	1.97e-05	50.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HNH
YHH1_k127_6531585_0	1123368.AUIS01000031_gene1420	2.429e-89	307.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,2NE68@225057|Acidithiobacillales	225057|Acidithiobacillales	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
YHH1_k127_6531585_1	439235.Dalk_1651	1.317e-16	85.0	COG0517@1|root,COG0517@2|Bacteria,1QUKQ@1224|Proteobacteria,42TPD@68525|delta/epsilon subdivisions,2WQQ5@28221|Deltaproteobacteria,2MK07@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YHH1_k127_6574135_0	1121272.KB903283_gene5138	0.0001856	53.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Big_3_5,Metallophos,ThuA,VCBS
YHH1_k127_6581456_1	1176165.CAJD01000015_gene954	2.946e-20	97.0	COG0797@1|root,COG0797@2|Bacteria,2IRQI@201174|Actinobacteria,4F9Z0@85019|Brevibacteriaceae	201174|Actinobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642,ko:K21688	-	-	-	-	ko00000	-	-	-	DPBB_1,DUF348,G5
YHH1_k127_6581456_0	472759.Nhal_2059	2.375e-49	187.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1X01T@135613|Chromatiales	135613|Chromatiales	HJ	TIGRFAM alpha-L-glutamate ligase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
YHH1_k127_6605880_0	483219.LILAB_16550	1.756e-09	60.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,42UMS@68525|delta/epsilon subdivisions,2WQA3@28221|Deltaproteobacteria,2YVD7@29|Myxococcales	28221|Deltaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287,ko:K18589	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	DHFR_1
YHH1_k127_6612885_2	1382306.JNIM01000001_gene3851	3.069e-39	160.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi	200795|Chloroflexi	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
YHH1_k127_6612885_0	471854.Dfer_5654	1.005e-126	417.0	COG1373@1|root,COG1373@2|Bacteria,4NHSW@976|Bacteroidetes,47JKG@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_6612885_1	926550.CLDAP_15350	2.658e-123	421.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
YHH1_k127_6617420_0	262543.Exig_2665	1.873e-43	177.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1U7NI@1239|Firmicutes,4HA3E@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_7,Response_reg
YHH1_k127_6617420_1	485918.Cpin_4113	1.606e-05	54.0	COG2911@1|root,COG2911@2|Bacteria,4NHHA@976|Bacteroidetes,1IVM6@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG
YHH1_k127_6630457_0	292459.STH1268	8.807e-69	251.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia	186801|Clostridia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
YHH1_k127_6630457_1	1124780.ANNU01000005_gene2364	3.239e-57	207.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,47JDW@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YHH1_k127_6634003_0	891968.Anamo_0894	4.867e-160	513.0	COG1155@1|root,COG1155@2|Bacteria,3TA3Y@508458|Synergistetes	508458|Synergistetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
YHH1_k127_6634003_4	555088.DealDRAFT_1680	8.429e-12	70.0	COG1436@1|root,COG1436@2|Bacteria,1VAX7@1239|Firmicutes,24MXC@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
YHH1_k127_6634003_3	1297617.JPJD01000013_gene926	8.537e-25	116.0	COG1527@1|root,COG1527@2|Bacteria,1U6WZ@1239|Firmicutes,249XD@186801|Clostridia,267RG@186813|unclassified Clostridiales	186801|Clostridia	C	ATP synthase (C/AC39) subunit	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
YHH1_k127_6634003_2	1120998.AUFC01000008_gene1086	3.734e-30	125.0	COG0636@1|root,COG0636@2|Bacteria,1V786@1239|Firmicutes,24HBF@186801|Clostridia,3WDFA@538999|Clostridiales incertae sedis	186801|Clostridia	C	ATP synthase subunit C	ntpK	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
YHH1_k127_6634003_1	1209989.TepiRe1_2243	3.823e-76	279.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,42EMM@68295|Thermoanaerobacterales	186801|Clostridia	C	116 kDa subunit	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
YHH1_k127_666212_1	28258.KP05_08860	1.156e-33	144.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria,1XR8W@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_666212_0	472759.Nhal_3271	1.68e-44	179.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,1WWWA@135613|Chromatiales	135613|Chromatiales	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
YHH1_k127_6705187_0	768679.TTX_0564	2.316e-46	176.0	COG0105@1|root,arCOG04313@2157|Archaea,2XQEV@28889|Crenarchaeota	28889|Crenarchaeota	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YHH1_k127_678176_0	869210.Marky_2230	5.992e-06	53.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CAP
YHH1_k127_6806151_1	1540257.JQMW01000013_gene965	1.662e-05	55.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,36JJM@31979|Clostridiaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
YHH1_k127_6806151_0	1267533.KB906737_gene1537	7.123e-07	63.0	COG3055@1|root,COG3485@1|root,COG3055@2|Bacteria,COG3485@2|Bacteria,3Y8A3@57723|Acidobacteria	57723|Acidobacteria	Q	protocatechuate 3,4-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6833785_0	1047013.AQSP01000118_gene1252	2.426e-132	436.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6889087_0	500632.CLONEX_03547	1.84e-21	96.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_6889735_1	795359.TOPB45_1621	4.898e-09	63.0	COG1943@1|root,COG1943@2|Bacteria,2GI5R@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_6889735_0	697282.Mettu_3886	3.468e-13	83.0	COG1749@1|root,COG2319@1|root,COG2372@1|root,COG1749@2|Bacteria,COG2319@2|Bacteria,COG2372@2|Bacteria,1MWJA@1224|Proteobacteria,1S1AJ@1236|Gammaproteobacteria,1XF66@135618|Methylococcales	135618|Methylococcales	N	WD40 repeat, subgroup	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,WD40
YHH1_k127_6904034_0	1123274.KB899411_gene3072	8.829e-07	59.0	COG1378@1|root,COG1378@2|Bacteria	2|Bacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_6921062_0	765420.OSCT_2657	1.092e-104	362.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi,374UZ@32061|Chloroflexia	32061|Chloroflexia	L	PFAM phosphoesterase, RecJ domain protein	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH1_k127_6955294_0	1288963.ADIS_3982	1.899e-23	102.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,47R60@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
YHH1_k127_6963585_0	1313304.CALK_0583	2.952e-11	74.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA
YHH1_k127_6981941_0	926569.ANT_22450	4.396e-47	188.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YHH1_k127_6983667_3	589924.Ferp_2388	1.581e-05	48.0	COG0500@1|root,arCOG04347@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Methyltransf_11
YHH1_k127_6983667_2	1121101.HMPREF1532_03332	7.304e-12	77.0	COG0438@1|root,COG0438@2|Bacteria,4PMJT@976|Bacteroidetes,2FSCS@200643|Bacteroidia,4AQJA@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_6983667_1	479433.Caci_8509	1.499e-14	85.0	COG0438@1|root,COG0438@2|Bacteria,2GQ6S@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
YHH1_k127_6983667_0	1121889.AUDM01000008_gene806	3.081e-19	95.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
YHH1_k127_7010910_0	1003195.SCAT_0072	1.806e-15	91.0	COG5297@1|root,COG5297@2|Bacteria,2GK92@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase family 6	guxA1	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,CBM_3,Glyco_hydro_6,fn3
YHH1_k127_7025940_0	316274.Haur_4419	3.577e-117	394.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi,3750Q@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
YHH1_k127_7025940_1	204773.HEAR1847	2.022e-08	66.0	COG0568@1|root,COG0568@2|Bacteria,1RCGB@1224|Proteobacteria,2VQU8@28216|Betaproteobacteria,47623@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
YHH1_k127_7042984_0	875454.BAEW01000006_gene1075	3.614e-16	93.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,22GQ5@1570339|Peptoniphilaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppsA	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH1_k127_7077953_0	309807.SRU_1720	1.114e-80	276.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1FK37@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH1_k127_71004_1	749927.AMED_7753	9.491e-09	58.0	COG4728@1|root,COG4728@2|Bacteria,2GSRP@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
YHH1_k127_71004_0	1121468.AUBR01000006_gene338	6.333e-66	237.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,42EZK@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
YHH1_k127_7144312_0	247490.KSU1_D0118	5.558e-61	216.0	COG0366@1|root,COG0366@2|Bacteria,2IXJN@203682|Planctomycetes	203682|Planctomycetes	G	alpha amylase catalytic	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
YHH1_k127_7194525_0	29306.JOBE01000002_gene2822	2.058e-36	154.0	COG1403@1|root,COG3209@1|root,COG1403@2|Bacteria,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN
YHH1_k127_7197622_0	105425.BBPL01000139_gene4949	7.249e-07	63.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM9_1,CHB_HEX_C_1,CarboxypepD_reg,DUF11,Kelch_1,NPCBM_assoc,OmpA,Pectate_lyase_3,SLH,VCBS
YHH1_k127_7197622_1	477184.KYC_25343	6.729e-05	48.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria,3T3NU@506|Alcaligenaceae	28216|Betaproteobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
YHH1_k127_7312197_2	411474.COPEUT_00145	7.977e-05	49.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
YHH1_k127_7312197_0	926550.CLDAP_09670	7.191e-25	111.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
YHH1_k127_7312197_1	649764.HMPREF0762_00180	7.438e-20	102.0	COG1686@1|root,COG1686@2|Bacteria,2GK3M@201174|Actinobacteria,4CUV4@84998|Coriobacteriia	84998|Coriobacteriia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
YHH1_k127_732829_3	926690.KE386573_gene1794	3.924e-17	87.0	COG0681@1|root,arCOG01739@2157|Archaea,2XX34@28890|Euryarchaeota,23VYJ@183963|Halobacteria	183963|Halobacteria	U	COG0681 Signal peptidase I	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
YHH1_k127_732829_2	435908.IDSA_08925	4.718e-24	112.0	2BH5I@1|root,32B6M@2|Bacteria,1RKHK@1224|Proteobacteria,1S7RV@1236|Gammaproteobacteria,2QGT3@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
YHH1_k127_732829_0	292564.Cyagr_1269	1.062e-75	271.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	XK27_00240	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_DeoR
YHH1_k127_732829_1	886379.AEWI01000017_gene1505	9.275e-38	149.0	COG3600@1|root,COG3600@2|Bacteria,4P4DA@976|Bacteroidetes,2G1KE@200643|Bacteroidia,3XKZQ@558415|Marinilabiliaceae	976|Bacteroidetes	S	Protein of unknown function (DUF4065)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065
YHH1_k127_7352088_0	660470.Theba_1526	5.627e-20	91.0	COG0695@1|root,COG0695@2|Bacteria,2GD7W@200918|Thermotogae	200918|Thermotogae	O	glutaredoxin-like protein, YruB-family	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
YHH1_k127_7352088_1	1411123.JQNH01000001_gene1343	0.0005459	48.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIGRFAM MazG family protein	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
YHH1_k127_7368071_2	56107.Cylst_5451	7.937e-07	54.0	2A73B@1|root,30VYY@2|Bacteria,1GI7P@1117|Cyanobacteria,1HT79@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
YHH1_k127_7368071_0	46234.ANA_C11858	7.664e-39	148.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH1_k127_7368071_1	1123367.C666_12575	6.394e-16	84.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2VIAK@28216|Betaproteobacteria,2KUGK@206389|Rhodocyclales	206389|Rhodocyclales	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18
YHH1_k127_7383000_0	867903.ThesuDRAFT_00551	5.386e-235	740.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,3WCDQ@538999|Clostridiales incertae sedis	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH1_k127_7385625_2	309801.trd_0060	1.204e-46	182.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
YHH1_k127_7385625_0	698758.AXY_15870	1.307e-67	243.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli	91061|Bacilli	D	Belongs to the SEDS family	spoVE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
YHH1_k127_7385625_1	1395513.P343_17455	3.975e-60	221.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,26NW3@186821|Sporolactobacillaceae	91061|Bacilli	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
YHH1_k127_7419037_3	243274.THEMA_06845	5.184e-19	88.0	COG0186@1|root,COG0186@2|Bacteria,2GD97@200918|Thermotogae	200918|Thermotogae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
YHH1_k127_7419037_1	1519464.HY22_03335	6.391e-38	145.0	COG0093@1|root,COG0093@2|Bacteria,1FDZR@1090|Chlorobi	1090|Chlorobi	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
YHH1_k127_7419037_2	945713.IALB_0923	3.661e-29	120.0	COG0198@1|root,COG0198@2|Bacteria	2|Bacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
YHH1_k127_7419037_0	641143.HMPREF9331_02058	9.769e-47	173.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,1HX1E@117743|Flavobacteriia,1EQ0H@1016|Capnocytophaga	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
YHH1_k127_7448730_2	1128421.JAGA01000002_gene390	9.45e-47	184.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,2NP3R@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_7448730_3	1121007.AUML01000001_gene1342	1.165e-45	168.0	COG0537@1|root,COG0537@2|Bacteria,4NEYS@976|Bacteroidetes	976|Bacteroidetes	FG	Histidine triad (HIT)	-	-	-	-	-	-	-	-	-	-	-	-	HIT,Methyltransf_23
YHH1_k127_7448730_0	298386.PBPRB1071	7.44e-82	284.0	COG4467@1|root,COG4467@2|Bacteria,1PPMF@1224|Proteobacteria,1S1PB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
YHH1_k127_7448730_1	314230.DSM3645_16010	1.111e-54	199.0	COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH1_k127_7448730_4	207559.Dde_1102	2.939e-30	122.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WKZE@28221|Deltaproteobacteria,2MGCG@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
YHH1_k127_7462316_0	1036674.A28LD_1478	6.992e-06	58.0	COG4386@1|root,COG4386@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,Laminin_G_3,Rib
YHH1_k127_7513197_0	33898.JRHJ01000076_gene431	7.29e-24	117.0	29V63@1|root,30GJR@2|Bacteria,2GXP8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7553662_0	1395571.TMS3_0100940	1.873e-28	121.0	2DC00@1|root,2ZC4V@2|Bacteria,1RBPR@1224|Proteobacteria,1S2KT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7623658_1	1366046.HIMB11_00396	1.148e-05	53.0	COG2244@1|root,COG2244@2|Bacteria,1P4US@1224|Proteobacteria,2UWU2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
YHH1_k127_7623658_0	337191.KTR9_3052	1.371e-71	262.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4GB6N@85026|Gordoniaceae	201174|Actinobacteria	E	Asparagine synthase	asnB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
YHH1_k127_7629198_0	111781.Lepto7376_1611	6.883e-06	58.0	COG1566@1|root,COG1566@2|Bacteria,1GHET@1117|Cyanobacteria,1HHYX@1150|Oscillatoriales	1117|Cyanobacteria	V	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
YHH1_k127_7753986_0	1041930.Mtc_0315	4.151e-149	497.0	COG1042@1|root,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,2N9F3@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM CoA-binding domain protein	acdAB	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
YHH1_k127_7763921_0	675635.Psed_2971	0.0004807	51.0	COG1414@1|root,COG1414@2|Bacteria,2GJAZ@201174|Actinobacteria,4E2AH@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	gylR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
YHH1_k127_7767962_1	1399115.U719_16550	6.187e-05	52.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,3WER5@539002|Bacillales incertae sedis	91061|Bacilli	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
YHH1_k127_7767962_0	370438.PTH_0001	9.193e-101	344.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,260P2@186807|Peptococcaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
YHH1_k127_7781226_3	330214.NIDE3501	1.817e-23	108.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
YHH1_k127_7781226_2	1235802.C823_03234	3.373e-29	128.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,25W82@186806|Eubacteriaceae	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
YHH1_k127_7781226_0	706587.Desti_3853	5.109e-89	312.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2MQ6S@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
YHH1_k127_7781226_1	1163671.JAGI01000002_gene3840	8.861e-61	222.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,36DVH@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_7794058_0	1385511.N783_21745	2.197e-68	248.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,2Y9H3@289201|Pontibacillus	91061|Bacilli	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_7809511_2	1217652.F954_00370	5.834e-05	50.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,3NKVX@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Type IV pilus assembly protein PilM;	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
YHH1_k127_7809511_0	204669.Acid345_4202	6.569e-27	121.0	COG1040@1|root,COG1040@2|Bacteria,3Y4SY@57723|Acidobacteria,2JJM7@204432|Acidobacteriia	204432|Acidobacteriia	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
YHH1_k127_7809511_1	511.JT27_18765	1.685e-07	62.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,3T1YA@506|Alcaligenaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
YHH1_k127_7926109_0	1304284.L21TH_1673	2.171e-43	168.0	COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,249IS@186801|Clostridia,36FFI@31979|Clostridiaceae	186801|Clostridia	O	Cytochrome c biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD,Redoxin
YHH1_k127_7926109_1	1121324.CLIT_11c00660	9.326e-12	75.0	COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,24MYD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
YHH1_k127_7937992_5	272942.RCAP_rcc02760	4.698e-10	64.0	COG3070@1|root,COG3070@2|Bacteria,1N0ND@1224|Proteobacteria,2UE8I@28211|Alphaproteobacteria,1FD1Q@1060|Rhodobacter	28211|Alphaproteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
YHH1_k127_7937992_0	266117.Rxyl_0312	3.706e-158	520.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4CQV5@84995|Rubrobacteria	84995|Rubrobacteria	EU	Peptidase S9, prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YHH1_k127_7937992_1	1123360.thalar_01041	6.705e-59	211.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH1_k127_7937992_2	1267533.KB906738_gene2343	1.55e-32	137.0	COG4803@1|root,COG4803@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
YHH1_k127_7937992_3	398527.Bphyt_5490	1.599e-20	100.0	COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,2VUMS@28216|Betaproteobacteria,1K4N1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
YHH1_k127_7937992_4	309803.CTN_1753	3.456e-10	68.0	COG1309@1|root,COG1309@2|Bacteria,2GDD9@200918|Thermotogae	200918|Thermotogae	K	tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
YHH1_k127_7948695_3	313612.L8106_15060	8.761e-63	221.0	COG0216@1|root,COG0216@2|Bacteria,1FZY4@1117|Cyanobacteria,1H81Q@1150|Oscillatoriales	1117|Cyanobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH1_k127_7948695_4	688269.Theth_1033	2.546e-50	188.0	COG0052@1|root,COG0052@2|Bacteria,2GCBI@200918|Thermotogae	200918|Thermotogae	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YHH1_k127_7948695_5	868595.Desca_1513	6.09e-43	166.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,260PI@186807|Peptococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
YHH1_k127_7948695_2	1032480.MLP_17940	1.032e-64	243.0	COG1215@1|root,COG1215@2|Bacteria,2IK1V@201174|Actinobacteria	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7948695_1	160492.XF_0741	3.07e-78	269.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1X40X@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YHH1_k127_7948695_0	552811.Dehly_1235	1.183e-79	289.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi,34CIT@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
YHH1_k127_7957434_1	1449346.JQMO01000003_gene6233	1.132e-09	70.0	COG1613@1|root,COG1613@2|Bacteria,2GNYM@201174|Actinobacteria,2M4VI@2063|Kitasatospora	201174|Actinobacteria	P	Sulfate ABC transporter periplasmic sulfate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
YHH1_k127_7957434_0	479434.Sthe_1821	4.423e-76	270.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi,27XRH@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
YHH1_k127_7957434_2	1210884.HG799470_gene14433	2.173e-05	48.0	COG1595@1|root,COG1595@2|Bacteria,2IZ91@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_7970050_0	485913.Krac_8438	7.143e-09	62.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
YHH1_k127_7973884_0	349161.Dred_1627	6.304e-53	211.0	COG1353@1|root,COG1353@2|Bacteria,1TRW5@1239|Firmicutes,24BI3@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein, Csm1 family	-	-	-	ko:K07016	-	-	-	-	ko00000,ko02048	-	-	-	HD
YHH1_k127_7983153_0	579137.Metvu_0945	2.5e-22	108.0	COG0574@1|root,arCOG01111@2157|Archaea,2XU2T@28890|Euryarchaeota,23Q5F@183939|Methanococci	183939|Methanococci	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH1_k127_7984428_0	1167006.UWK_03515	6.66e-54	193.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria,2MJMW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_7999585_0	403833.Pmob_0994	1.651e-120	404.0	COG0415@1|root,COG0415@2|Bacteria,2GDRQ@200918|Thermotogae	200918|Thermotogae	H	PFAM DNA photolyase FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
YHH1_k127_7999585_3	1236689.MMALV_07650	5.037e-12	67.0	COG1132@1|root,arCOG02841@2157|Archaea,2XSW0@28890|Euryarchaeota,3F2ZV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	P	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH1_k127_7999585_2	1206720.BAFQ01000167_gene4407	1.552e-15	86.0	COG0339@1|root,COG0438@1|root,COG0631@1|root,COG0653@1|root,COG1595@1|root,COG2172@1|root,COG2197@1|root,COG4099@1|root,COG0339@2|Bacteria,COG0438@2|Bacteria,COG0631@2|Bacteria,COG0653@2|Bacteria,COG1595@2|Bacteria,COG2172@2|Bacteria,COG2197@2|Bacteria,COG4099@2|Bacteria,2I67X@201174|Actinobacteria,4FZ8D@85025|Nocardiaceae	201174|Actinobacteria	KTU	helix_turn_helix, Lux Regulon	-	-	3.5.4.40	ko:K18286	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	GerE,Glycos_transf_1,GntR,HTH_3,PP2C_2
YHH1_k127_7999585_1	1472716.KBK24_0102120	1.433e-89	317.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2VK4K@28216|Betaproteobacteria,1K4SM@119060|Burkholderiaceae	28216|Betaproteobacteria	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Response_reg
YHH1_k127_8026975_7	1121870.AUAA01000030_gene3299	4.425e-06	49.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	tnpA1	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
YHH1_k127_8026975_5	2903.EOD27628	1.243e-24	111.0	KOG1584@1|root,KOG1584@2759|Eukaryota	2759|Eukaryota	S	sulfotransferase activity	St1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006805,GO:0006950,GO:0006952,GO:0008146,GO:0008150,GO:0008152,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0016740,GO:0016782,GO:0042221,GO:0042742,GO:0043207,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0051923,GO:0070887,GO:0071466,GO:0098542	2.8.2.1,2.8.2.4	ko:K01014,ko:K01016,ko:K01025	ko00140,ko05204,map00140,map05204	-	R01242,R02350	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
YHH1_k127_8026975_6	694429.Pyrfu_0320	5.856e-08	57.0	COG5428@1|root,arCOG02270@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
YHH1_k127_8026975_1	765420.OSCT_1516	3.508e-41	164.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi,37506@32061|Chloroflexia	32061|Chloroflexia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YHH1_k127_8026975_0	747365.Thena_0155	1.691e-81	289.0	COG0342@1|root,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,42F9I@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YHH1_k127_8026975_2	879212.DespoDRAFT_01012	1.179e-36	140.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42VQB@68525|delta/epsilon subdivisions,2WQFH@28221|Deltaproteobacteria,2MKMC@213118|Desulfobacterales	28221|Deltaproteobacteria	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
YHH1_k127_8026975_4	710696.Intca_2901	1.422e-30	123.0	COG3549@1|root,COG3549@2|Bacteria,2HVCI@201174|Actinobacteria,4FJJ2@85021|Intrasporangiaceae	201174|Actinobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
YHH1_k127_8026975_3	406818.XBJ1_1349	1.106e-35	148.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	IS30 family	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
YHH1_k127_8031425_1	595536.ADVE02000001_gene1353	1.226e-51	185.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria,36X9I@31993|Methylocystaceae	28211|Alphaproteobacteria	K	RNA polymerase beta subunit external 1 domain	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH1_k127_8031425_0	555079.Toce_0112	2.452e-269	853.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,42FED@68295|Thermoanaerobacterales	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH1_k127_8039329_0	880073.Calab_1805	1.613e-32	131.0	COG1595@1|root,COG1595@2|Bacteria,2NRM3@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_8039329_1	880073.Calab_1806	2.059e-17	92.0	295PX@1|root,2ZT19@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8045097_1	479434.Sthe_1608	1.131e-08	56.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi,27XZ9@189775|Thermomicrobia	189775|Thermomicrobia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
YHH1_k127_8045097_0	1541959.KQ51_00158	1.072e-47	174.0	COG0080@1|root,COG0080@2|Bacteria,3WTDP@544448|Tenericutes	544448|Tenericutes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
YHH1_k127_8045097_2	1192759.AKIB01000020_gene3029	7.884e-05	45.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2TW3U@28211|Alphaproteobacteria,2K1A6@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_8046595_0	983545.Glaag_4332	1.893e-09	70.0	COG2931@1|root,COG3209@1|root,COG3408@1|root,COG4733@1|root,COG5306@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3408@2|Bacteria,COG4733@2|Bacteria,COG5306@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,464DD@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
YHH1_k127_8090914_0	558152.IQ37_13390	1.035e-86	304.0	COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,1HXBV@117743|Flavobacteriia,3ZR3I@59732|Chryseobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
YHH1_k127_8090914_2	870187.Thini_4510	7.2e-07	56.0	2C9Y3@1|root,33JDQ@2|Bacteria,1NQEK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8090914_1	1121335.Clst_1376	4.091e-19	94.0	COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia,3WJ4G@541000|Ruminococcaceae	186801|Clostridia	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
YHH1_k127_8098090_0	1454007.JAUG01000134_gene814	2e-09	63.0	COG1373@1|root,COG1373@2|Bacteria,4NHSW@976|Bacteroidetes,1IWA8@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_8128245_0	1128421.JAGA01000002_gene1668	1.746e-20	98.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	2.4.2.21,5.4.2.12	ko:K00768,ko:K15634	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R01518,R04148	RC00033,RC00063,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
YHH1_k127_8136437_0	37659.JNLN01000001_gene991	2.739e-206	662.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH1_k127_8143947_0	649638.Trad_0736	5.715e-21	105.0	COG0438@1|root,COG0438@2|Bacteria,1WJTX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_8149388_0	1207055.C100_05415	6.891e-07	57.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,2K082@204457|Sphingomonadales	204457|Sphingomonadales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
YHH1_k127_8153808_0	290397.Adeh_3947	1.426e-56	207.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2YZII@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
YHH1_k127_8153808_1	771875.Ferpe_0732	2.72e-05	48.0	COG1373@1|root,COG1373@2|Bacteria,2GE85@200918|Thermotogae	200918|Thermotogae	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_8160738_0	1519464.HY22_02080	3.671e-137	447.0	COG0449@1|root,COG0449@2|Bacteria,1FDCR@1090|Chlorobi	1090|Chlorobi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YHH1_k127_8160738_1	324925.Ppha_1175	6.846e-22	100.0	COG0353@1|root,COG0353@2|Bacteria,1FDRD@1090|Chlorobi	1090|Chlorobi	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
YHH1_k127_8218314_0	340099.Teth39_0117	1.501e-127	416.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,42FZU@68295|Thermoanaerobacterales	186801|Clostridia	O	TIGRFAM SUF system FeS cluster assembly, SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
YHH1_k127_8235039_0	316055.RPE_1392	1.802e-25	108.0	COG3041@1|root,COG3041@2|Bacteria,1N0K0@1224|Proteobacteria,2UC2Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Addiction module	yafQ	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
YHH1_k127_8235039_1	1235790.C805_00291	2.79e-09	61.0	COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,24R5Z@186801|Clostridia,25ZGQ@186806|Eubacteriaceae	186801|Clostridia	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
YHH1_k127_8236074_0	1122238.AULR01000012_gene1284	0.0006703	51.0	COG1361@1|root,COG1361@2|Bacteria,2HZGC@201174|Actinobacteria,4FNVG@85023|Microbacteriaceae	201174|Actinobacteria	M	Bacterial protein of unknown function (DUF916)	-	-	-	-	-	-	-	-	-	-	-	-	DUF916
YHH1_k127_8242796_5	289377.HL41_03190	2.494e-12	72.0	COG0845@1|root,COG0845@2|Bacteria,2GGXV@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
YHH1_k127_8242796_2	696281.Desru_0622	7.401e-71	246.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,261I1@186807|Peptococcaceae	186801|Clostridia	P	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_8242796_1	1120973.AQXL01000125_gene3124	4.93e-73	261.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HATE@91061|Bacilli,2795F@186823|Alicyclobacillaceae	91061|Bacilli	V	MacB-like periplasmic core domain	macB1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_8242796_4	1121365.AQXB01000006_gene688	1.072e-12	77.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,22KMF@1653|Corynebacteriaceae	201174|Actinobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YHH1_k127_8242796_0	580340.Tlie_1478	9.218e-80	274.0	COG3959@1|root,COG3959@2|Bacteria,3TA23@508458|Synergistetes	508458|Synergistetes	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YHH1_k127_8242796_3	997884.HMPREF1068_01457	1.462e-25	110.0	COG0399@1|root,COG0399@2|Bacteria,4PMNM@976|Bacteroidetes	976|Bacteroidetes	M	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YHH1_k127_8253666_1	83406.HDN1F_22760	6.198e-05	49.0	COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,1S9CP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
YHH1_k127_8253666_0	357808.RoseRS_1280	1.766e-48	184.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi,37530@32061|Chloroflexia	32061|Chloroflexia	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
YHH1_k127_8253669_0	351160.RCIX2384	4.936e-103	349.0	COG0651@1|root,arCOG01537@2157|Archaea,2XWXC@28890|Euryarchaeota,2NADW@224756|Methanomicrobia	224756|Methanomicrobia	C	plastoquinone (Complex I)	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
YHH1_k127_8253669_1	237368.SCABRO_00633	2.097e-75	269.0	COG3261@1|root,COG3261@2|Bacteria,2IZ46@203682|Planctomycetes	203682|Planctomycetes	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
YHH1_k127_8254818_3	1401067.HMPREF0872_04785	6.256e-18	87.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4H3XP@909932|Negativicutes	909932|Negativicutes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
YHH1_k127_8254818_0	869210.Marky_1319	5.505e-109	369.0	COG0017@1|root,COG0017@2|Bacteria,1WJAX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspC	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YHH1_k127_8254818_1	575540.Isop_1873	3.576e-96	325.0	COG0180@1|root,COG0180@2|Bacteria,2IWRB@203682|Planctomycetes	203682|Planctomycetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH1_k127_8254818_2	1502851.FG93_00182	1.138e-37	161.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
YHH1_k127_8345887_4	1236973.JCM9157_2248	3.12e-07	59.0	2EIC9@1|root,33C3K@2|Bacteria,1UCCP@1239|Firmicutes,4INV2@91061|Bacilli,1ZNZJ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8345887_0	1305737.JAFX01000001_gene3165	1.285e-63	228.0	COG3177@1|root,COG3177@2|Bacteria,4NIG2@976|Bacteroidetes	976|Bacteroidetes	S	Fic family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH1_k127_8345887_1	765913.ThidrDRAFT_3568	6.829e-48	175.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1WVUR@135613|Chromatiales	135613|Chromatiales	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
YHH1_k127_8345887_3	1123400.KB904749_gene813	6.39e-08	57.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,1SH40@1236|Gammaproteobacteria,461GH@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
YHH1_k127_8345887_2	765911.Thivi_0412	5.344e-09	57.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1WW0U@135613|Chromatiales	135613|Chromatiales	O	HflC and HflK could regulate a protease	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
YHH1_k127_8355155_0	575593.HMPREF0491_01895	7.32e-54	196.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,27IW0@186928|unclassified Lachnospiraceae	186801|Clostridia	J	tRNA nucleotidyltransferase domain 2 putative	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
YHH1_k127_8385816_0	1408444.JHYC01000011_gene1002	5.366e-111	364.0	COG3617@1|root,COG3617@2|Bacteria,1QX1C@1224|Proteobacteria	1224|Proteobacteria	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
YHH1_k127_8403683_5	933262.AXAM01000011_gene1786	0.0001727	48.0	COG0864@1|root,COG0864@2|Bacteria	2|Bacteria	K	response to nickel cation	ndoAI	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	RHH_1
YHH1_k127_8403683_2	1408311.JNJM01000027_gene2781	1.713e-20	95.0	COG1569@1|root,COG1569@2|Bacteria,1VHAV@1239|Firmicutes,24QPU@186801|Clostridia,2PTBZ@265975|Oribacterium	186801|Clostridia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH1_k127_8403683_1	485918.Cpin_0421	4.707e-85	297.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,1IPKH@117747|Sphingobacteriia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
YHH1_k127_8403683_3	234267.Acid_4367	1.576e-11	66.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin,YafQ_toxin
YHH1_k127_8403683_4	660470.Theba_1115	7.034e-06	51.0	COG2336@1|root,COG2336@2|Bacteria	2|Bacteria	T	PFAM SpoVT AbrB	-	-	-	ko:K07172,ko:K18842	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH1_k127_8403683_0	118005.AWNK01000005_gene1511	7.904e-120	391.0	COG3617@1|root,COG3617@2|Bacteria	2|Bacteria	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
YHH1_k127_8412607_4	1304284.L21TH_1433	3.869e-21	96.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,36EDX@31979|Clostridiaceae	186801|Clostridia	L	Hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YHH1_k127_8412607_7	1121346.KB899814_gene1824	2.055e-05	55.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,26Y3R@186822|Paenibacillaceae	91061|Bacilli	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
YHH1_k127_8412607_1	1165096.ARWF01000001_gene1850	8.683e-36	141.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,2KMPH@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YHH1_k127_8412607_6	1463936.JOJI01000093_gene1361	1.587e-10	63.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
YHH1_k127_8412607_2	1256908.HMPREF0373_02937	1.483e-26	116.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,25UWQ@186806|Eubacteriaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YHH1_k127_8412607_0	1110502.TMO_1129	3.735e-134	436.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,2JPIZ@204441|Rhodospirillales	204441|Rhodospirillales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
YHH1_k127_8412607_5	1050201.KB913034_gene1038	1.334e-14	76.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,3VPPT@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Belongs to the FtsK SpoIIIE SftA family	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YHH1_k127_8421000_0	1205910.B005_0329	5.519e-07	57.0	COG1051@1|root,COG1051@2|Bacteria,2INEY@201174|Actinobacteria,4EPJS@85012|Streptosporangiales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH1_k127_8425544_1	323097.Nham_3027	0.0004911	52.0	COG3420@1|root,COG3420@2|Bacteria,1QWWH@1224|Proteobacteria,2TX6H@28211|Alphaproteobacteria,3K6S6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,W_rich_C
YHH1_k127_8425544_0	398512.JQKC01000017_gene3065	0.0002841	48.0	COG0296@1|root,COG3507@1|root,COG0296@2|Bacteria,COG3507@2|Bacteria,1TR04@1239|Firmicutes,24ATC@186801|Clostridia,3WG7I@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.55	ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	AbfB,Big_3,CBM_2,CBM_4_9,CBM_6,Esterase,Glyco_hydro_43,RicinB_lectin_2
YHH1_k127_8437849_1	1232410.KI421424_gene1844	8.345e-57	205.0	COG1896@1|root,COG1896@2|Bacteria,1R71H@1224|Proteobacteria,42NGN@68525|delta/epsilon subdivisions,2WKMF@28221|Deltaproteobacteria,43S2K@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
YHH1_k127_8437849_2	1158345.JNLL01000001_gene1630	3.965e-14	76.0	COG1254@1|root,COG1254@2|Bacteria,2G49Q@200783|Aquificae	200783|Aquificae	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YHH1_k127_8437849_0	1198452.Jab_2c11750	1.873e-57	208.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,4727W@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
YHH1_k127_8482828_0	106370.Francci3_3284	2.162e-12	73.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4ESC7@85013|Frankiales	201174|Actinobacteria	T	PFAM response regulator receiver	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_849410_0	596324.TREVI0001_2156	6.928e-110	365.0	COG0542@1|root,COG0542@2|Bacteria,2J57C@203691|Spirochaetes	203691|Spirochaetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH1_k127_8530892_0	1499967.BAYZ01000076_gene830	1.64e-33	138.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YHH1_k127_8530892_1	309801.trd_1225	9.347e-17	87.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi,27YDN@189775|Thermomicrobia	189775|Thermomicrobia	CO	Thioredoxin-like	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
YHH1_k127_8538824_1	316274.Haur_4657	5.553e-19	100.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2GA9R@200795|Chloroflexi,374ZK@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_8,dCache_3
YHH1_k127_8538824_2	768704.Desmer_3969	1.138e-18	93.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,248B6@186801|Clostridia,263SZ@186807|Peptococcaceae	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_8538824_0	502025.Hoch_2558	1.18e-30	130.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MZW@68525|delta/epsilon subdivisions,2WIV1@28221|Deltaproteobacteria,2YUVS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PocR
YHH1_k127_8547908_0	999411.HMPREF1092_00519	2.532e-07	59.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,36EI6@31979|Clostridiaceae	186801|Clostridia	U	Belongs to the V-ATPase 116 kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
YHH1_k127_8558254_0	1123388.AQWU01000065_gene1966	1.758e-98	340.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1WIM7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
YHH1_k127_8574235_0	296587.XP_002504438.1	8.031e-17	88.0	COG4886@1|root,KOG0619@2759|Eukaryota,388K9@33090|Viridiplantae,34JK4@3041|Chlorophyta	2759|Eukaryota	S	Leucine-rich repeats, typical (most populated) subfamily	-	-	-	ko:K19613	ko04014,map04014	-	-	-	ko00000,ko00001	-	-	-	COR,LRR_1,LRR_4,LRR_8,Peptidase_C14,Roc,U-box
YHH1_k127_8574235_1	649349.Lbys_0684	2.385e-10	72.0	COG3656@1|root,COG3656@2|Bacteria,4NHDQ@976|Bacteroidetes,47PJR@768503|Cytophagia	976|Bacteroidetes	G	Fibronectin type III domain protein	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	-
YHH1_k127_8631358_4	1123070.KB899268_gene2442	4.119e-09	58.0	COG0227@1|root,COG0227@2|Bacteria,46TBF@74201|Verrucomicrobia,2IUUU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
YHH1_k127_8631358_2	1166018.FAES_1251	3.194e-55	202.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,47KW6@768503|Cytophagia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
YHH1_k127_8631358_1	563031.HMPREF0666_02951	4.656e-61	224.0	COG3177@1|root,COG3177@2|Bacteria,4NSD2@976|Bacteroidetes,2FQ4Z@200643|Bacteroidia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Penicillinase_R
YHH1_k127_8631358_3	1537915.JU57_02855	3.856e-22	102.0	COG2337@1|root,COG2337@2|Bacteria,1Q23M@1224|Proteobacteria,42UXQ@68525|delta/epsilon subdivisions,2YPYA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH1_k127_8631358_0	479434.Sthe_1252	1.509e-90	310.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi,27XWV@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
YHH1_k127_865941_2	1499968.TCA2_4752	6.021e-19	89.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,26Q9M@186822|Paenibacillaceae	91061|Bacilli	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
YHH1_k127_865941_0	1120973.AQXL01000135_gene1389	1.721e-90	312.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,278QW@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
YHH1_k127_865941_1	1168289.AJKI01000021_gene1783	1.615e-31	129.0	COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,2G1ZP@200643|Bacteroidia,3XIKZ@558415|Marinilabiliaceae	976|Bacteroidetes	K	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
YHH1_k127_8659739_0	163164.WD_0259	2.259e-117	387.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,2TU1T@28211|Alphaproteobacteria,47FHS@766|Rickettsiales	766|Rickettsiales	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
YHH1_k127_8659739_1	1410630.JNKP01000006_gene192	3.459e-31	126.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,27MQ4@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
YHH1_k127_8659739_3	500633.CLOHIR_01610	4.719e-15	79.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,25R9X@186804|Peptostreptococcaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YHH1_k127_8659739_2	1267533.KB906735_gene5102	4.041e-24	105.0	COG0203@1|root,COG0203@2|Bacteria,3Y4JF@57723|Acidobacteria,2JJ8Q@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
YHH1_k127_8659739_4	573413.Spirs_0980	9.733e-05	46.0	COG0202@1|root,COG0202@2|Bacteria,2J58K@203691|Spirochaetes	203691|Spirochaetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YHH1_k127_8725633_0	1382306.JNIM01000001_gene2868	5.223e-128	422.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YHH1_k127_8725633_1	667014.Thein_1585	1.677e-58	213.0	COG0758@1|root,COG0758@2|Bacteria,2GHI2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
YHH1_k127_8752539_0	1143323.M787_0721	1.286e-47	180.0	COG1478@1|root,COG1478@2|Bacteria	2|Bacteria	S	coenzyme F420-1:gamma-L-glutamate ligase activity	CP_1112	-	6.3.2.12,6.3.2.17,6.3.2.31,6.3.2.34	ko:K12234,ko:K22099	ko00680,ko00790,ko01120,map00680,map00790,map01120	M00378,M00840	R00942,R02237,R04241,R09399,R09400	RC00064,RC00090,RC00141,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
YHH1_k127_8763743_0	309801.trd_0965	1.161e-89	307.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia	189775|Thermomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YHH1_k127_8763743_6	1122939.ATUD01000003_gene3585	1.285e-13	77.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CQD8@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
YHH1_k127_8763743_2	402777.KB235904_gene4616	1.835e-34	141.0	COG0098@1|root,COG0098@2|Bacteria,1G1EF@1117|Cyanobacteria,1H7SH@1150|Oscillatoriales	1117|Cyanobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rps5	GO:0003674,GO:0003735,GO:0005198,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
YHH1_k127_8763743_4	1123313.ATUT01000003_gene768	8.257e-26	110.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,3VQGV@526524|Erysipelotrichia	526524|Erysipelotrichia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
YHH1_k127_8763743_1	1201288.M900_2683	7.237e-52	190.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2MT1B@213481|Bdellovibrionales,2WN9B@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
YHH1_k127_8763743_3	525245.HMPREF0044_0413	3.409e-26	115.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4D5IC@85005|Actinomycetales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
YHH1_k127_8763743_5	1293054.HSACCH_00074	5.824e-21	94.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3WAWA@53433|Halanaerobiales	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
YHH1_k127_8843357_2	1123389.ATXJ01000039_gene146	1.116e-05	57.0	COG1332@1|root,COG1332@2|Bacteria,1WJAU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	RAMP protein, Csm5	-	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
YHH1_k127_8843357_0	868595.Desca_0575	2.489e-26	121.0	COG1567@1|root,COG1567@2|Bacteria,1VK2V@1239|Firmicutes	1239|Firmicutes	L	CRISPR-associated RAMP protein, Csm4 family	-	-	-	ko:K19139	-	-	-	-	ko00000,ko02048	-	-	-	-
YHH1_k127_8843357_1	1121289.JHVL01000036_gene2572	8.506e-20	92.0	2E4E6@1|root,32Z9E@2|Bacteria,1VE04@1239|Firmicutes,24NHQ@186801|Clostridia,36M0U@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF1874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1874
YHH1_k127_8911177_0	187303.BN69_1880	1.852e-55	204.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	nanK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH1_k127_8916340_0	207559.Dde_0551	3.421e-76	263.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2WIXK@28221|Deltaproteobacteria,2M8AU@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Endonuclease Exonuclease phosphatase	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
YHH1_k127_8926673_1	252305.OB2597_04223	8.592e-08	59.0	COG2865@1|root,COG2865@2|Bacteria,1RDDZ@1224|Proteobacteria,2U7CD@28211|Alphaproteobacteria,2PD3S@252301|Oceanicola	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8926673_0	1238186.AOCN01000022_gene2512	3.009e-24	107.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4FNQN@85023|Microbacteriaceae	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
YHH1_k127_893026_1	1123008.KB905696_gene2961	4.71e-20	95.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia,22WAM@171551|Porphyromonadaceae	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
YHH1_k127_893026_2	743719.PaelaDRAFT_2085	1.051e-13	77.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,26XDH@186822|Paenibacillaceae	91061|Bacilli	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
YHH1_k127_893026_0	545693.BMQ_2117	1.52e-71	252.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1ZASX@1386|Bacillus	91061|Bacilli	M	UTP-glucose-1-phosphate uridylyltransferase	yngB	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YHH1_k127_8935736_2	448385.sce4409	1.083e-27	129.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WIVP@28221|Deltaproteobacteria,2YUDK@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
YHH1_k127_8935736_0	1499967.BAYZ01000118_gene3299	1.335e-74	277.0	COG4953@1|root,COG4953@2|Bacteria,2NQMA@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
YHH1_k127_8935736_1	512565.AMIS_32630	1.691e-54	196.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria,4DIUT@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
YHH1_k127_8948127_0	761193.Runsl_0636	2.674e-72	258.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,47MF2@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_8988688_0	109760.SPPG_02303T0	1.343e-11	72.0	KOG2592@1|root,KOG2592@2759|Eukaryota,38BDN@33154|Opisthokonta,3NW06@4751|Fungi	4751|Fungi	S	Membrane protein tms1	TMS1	GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005886,GO:0006575,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006658,GO:0006665,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008324,GO:0008509,GO:0008514,GO:0008610,GO:0009058,GO:0009987,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015194,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015825,GO:0015849,GO:0016020,GO:0016021,GO:0019637,GO:0022857,GO:0022889,GO:0030148,GO:0031090,GO:0031224,GO:0032329,GO:0034220,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044425,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046467,GO:0046486,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098588,GO:0098655,GO:0098656,GO:0098805,GO:0098852,GO:1901564,GO:1901566,GO:1901576,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	Serinc
YHH1_k127_9060927_1	983544.Lacal_1565	8.327e-06	50.0	28IFP@1|root,2Z8HD@2|Bacteria,4NR7F@976|Bacteroidetes,1I3PF@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3644)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3644
YHH1_k127_9060927_0	595460.RRSWK_05840	5.871e-117	389.0	COG3464@1|root,COG3464@2|Bacteria,2J2VZ@203682|Planctomycetes	2|Bacteria	L	Transposase	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
YHH1_k127_9083847_0	411467.BACCAP_04658	1.492e-72	251.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,267TJ@186813|unclassified Clostridiales	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
YHH1_k127_909046_1	460265.Mnod_7379	2.269e-09	63.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2UBXX@28211|Alphaproteobacteria,1JVC9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02113,ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
YHH1_k127_909046_0	247490.KSU1_D0180	2.561e-19	95.0	COG0209@1|root,COG0209@2|Bacteria	2|Bacteria	F	ribonucleoside-diphosphate reductase activity	rtpR	-	1.1.98.6,1.17.4.1	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC
YHH1_k127_9097573_0	1157490.EL26_10195	4.005e-173	548.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,2787C@186823|Alicyclobacillaceae	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10965	ATP-synt_ab,ATP-synt_ab_N
YHH1_k127_91847_0	1003195.SCAT_4152	7.976e-96	344.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YHH1_k127_91847_1	1382306.JNIM01000001_gene2868	4.763e-63	219.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YHH1_k127_9195519_2	1123274.KB899411_gene3072	1.355e-20	102.0	COG1378@1|root,COG1378@2|Bacteria	2|Bacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_9195519_3	1432055.GLUCORHAEAF1_09605	1.646e-13	78.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,2U05J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
YHH1_k127_9195519_1	485913.Krac_6901	2.006e-45	170.0	COG0127@1|root,COG0127@2|Bacteria	2|Bacteria	F	nucleoside triphosphate catabolic process	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	-	R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Ham1p_like
YHH1_k127_9195519_4	652103.Rpdx1_4373	7.485e-12	75.0	COG1378@1|root,COG1378@2|Bacteria,1PZ3N@1224|Proteobacteria,2UHQ6@28211|Alphaproteobacteria,3K4P9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_9195519_0	1454007.JAUG01000004_gene2697	4.981e-97	331.0	COG1373@1|root,COG1373@2|Bacteria,4NZYR@976|Bacteroidetes,1IW10@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_9201026_0	886293.Sinac_1249	1.447e-220	738.0	COG3459@1|root,COG3459@2|Bacteria,2IYJ0@203682|Planctomycetes	203682|Planctomycetes	G	Putative glucoamylase	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
YHH1_k127_9204899_0	443906.CMM_1482	1.172e-35	146.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4FKJ5@85023|Microbacteriaceae	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
YHH1_k127_9211580_0	484770.UFO1_2603	2.359e-94	334.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H6QR@909932|Negativicutes	909932|Negativicutes	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
YHH1_k127_9211580_1	1047013.AQSP01000140_gene2513	2.661e-44	174.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
YHH1_k127_9212406_0	472759.Nhal_1612	1.341e-156	527.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1WW7J@135613|Chromatiales	135613|Chromatiales	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
YHH1_k127_9218034_0	1123288.SOV_2c12390	9.193e-30	133.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4H2H6@909932|Negativicutes	909932|Negativicutes	V	Efflux ABC transporter permease protein	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH1_k127_9317093_0	1229172.JQFA01000004_gene1418	2.753e-130	433.0	COG0317@1|root,COG0317@2|Bacteria,1G0KC@1117|Cyanobacteria,1H7CJ@1150|Oscillatoriales	1117|Cyanobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
YHH1_k127_9317093_1	926569.ANT_13970	5.611e-54	207.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YHH1_k127_9329821_0	696369.KI912183_gene2544	1.46e-136	446.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,260MA@186807|Peptococcaceae	186801|Clostridia	L	PFAM transposase, mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
YHH1_k127_9329821_1	1236497.BAJQ01000009_gene1250	2.603e-11	63.0	COG1403@1|root,COG1479@1|root,COG1403@2|Bacteria,COG1479@2|Bacteria,4NGH2@976|Bacteroidetes,2FQXX@200643|Bacteroidia	976|Bacteroidetes	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF262,HNH
YHH1_k127_933991_0	324925.Ppha_1581	6.703e-196	637.0	COG2217@1|root,COG2217@2|Bacteria,1FDP1@1090|Chlorobi	1090|Chlorobi	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
YHH1_k127_933991_1	1121934.AUDX01000009_gene1124	2.905e-20	93.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4FPQS@85023|Microbacteriaceae	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
YHH1_k127_933991_2	1449976.KALB_960	3.607e-08	66.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DZ8E@85010|Pseudonocardiales	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	htrA	GO:0000785,GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005783,GO:0005789,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006915,GO:0006950,GO:0006974,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008236,GO:0008630,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009894,GO:0009898,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010467,GO:0010506,GO:0010604,GO:0010638,GO:0010646,GO:0010647,GO:0010648,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016485,GO:0016540,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030162,GO:0030163,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031329,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031984,GO:0032268,GO:0032270,GO:0032526,GO:0032991,GO:0033043,GO:0033554,GO:0033993,GO:0034097,GO:0034599,GO:0034605,GO:0035456,GO:0035458,GO:0035556,GO:0035631,GO:0042175,GO:0042221,GO:0042802,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043235,GO:0043280,GO:0043281,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044429,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045786,GO:0045862,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051082,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051336,GO:0051345,GO:0051604,GO:0051716,GO:0051726,GO:0052547,GO:0052548,GO:0060255,GO:0060548,GO:0065003,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0070206,GO:0070207,GO:0070848,GO:0070887,GO:0071229,GO:0071300,GO:0071310,GO:0071345,GO:0071363,GO:0071396,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0097190,GO:0097193,GO:0097194,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098802,GO:0098827,GO:0140096,GO:1900407,GO:1900408,GO:1901214,GO:1901215,GO:1901564,GO:1901565,GO:1901575,GO:1901700,GO:1901701,GO:1902175,GO:1902176,GO:1902494,GO:1902531,GO:1902532,GO:1902882,GO:1902883,GO:1903146,GO:1903201,GO:1903202,GO:1905286,GO:1905368,GO:1905369,GO:1905370,GO:2000116,GO:2001056,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001238,GO:2001239,GO:2001241,GO:2001242,GO:2001243,GO:2001267,GO:2001269	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
YHH1_k127_9348008_0	745718.JADT01000013_gene1385	2.757e-38	148.0	COG0791@1|root,COG0791@2|Bacteria,4NPFE@976|Bacteroidetes,1I29F@117743|Flavobacteriia	976|Bacteroidetes	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
YHH1_k127_936237_0	1123376.AUIU01000016_gene319	4.423e-53	190.0	COG3654@1|root,COG3943@1|root,COG3654@2|Bacteria,COG3943@2|Bacteria,3J0RS@40117|Nitrospirae	40117|Nitrospirae	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
YHH1_k127_936237_1	483219.LILAB_12465	3.925e-29	132.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WJRZ@28221|Deltaproteobacteria,2YW7G@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2101	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH1_k127_9368447_0	749222.Nitsa_1626	2.934e-59	216.0	COG3677@1|root,COG3677@2|Bacteria,1RBA7@1224|Proteobacteria,4304X@68525|delta/epsilon subdivisions,2YRUF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9368447_1	929556.Solca_1900	1.722e-13	70.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1IPQZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YHH1_k127_9377220_0	765420.OSCT_1547	0.0005072	51.0	COG1378@1|root,COG1378@2|Bacteria,2GANE@200795|Chloroflexi,376UQ@32061|Chloroflexia	32061|Chloroflexia	K	PFAM transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
YHH1_k127_9389367_0	391624.OIHEL45_06480	2.351e-74	273.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
YHH1_k127_9395132_3	1256908.HMPREF0373_01914	2.583e-07	58.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,25W7R@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
YHH1_k127_9395132_4	1408473.JHXO01000001_gene2324	1.236e-06	61.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH1_k127_9395132_0	1129374.AJE_15274	9.563e-24	104.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria,467QY@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
YHH1_k127_941590_0	1463856.JOHY01000035_gene1862	1.119e-63	231.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
YHH1_k127_9451112_1	1961.JOAK01000008_gene4056	4.02e-05	53.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
YHH1_k127_9451112_0	745718.JADT01000019_gene1519	1.081e-27	125.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
YHH1_k127_9460138_0	1120968.AUBX01000012_gene2874	0.0002481	49.0	COG2928@1|root,COG2928@2|Bacteria,4PAZD@976|Bacteroidetes,47UW1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
YHH1_k127_9466145_0	761193.Runsl_5288	5.74e-44	165.0	COG1373@1|root,COG1373@2|Bacteria,4NEMX@976|Bacteroidetes,47NCQ@768503|Cytophagia	976|Bacteroidetes	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_9466145_2	76114.ebA3774	2.199e-05	52.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH1_k127_9466145_1	489825.LYNGBM3L_13550	5.22e-09	61.0	COG3041@1|root,COG3041@2|Bacteria,1G87N@1117|Cyanobacteria,1HCJW@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	YafQ_toxin
YHH1_k127_947836_0	1379698.RBG1_1C00001G1066	4.577e-95	328.0	COG0260@1|root,COG0260@2|Bacteria,2NNKH@2323|unclassified Bacteria	2|Bacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1,3.4.11.5	ko:K01255,ko:K01259	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00135,R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
YHH1_k127_9500275_5	1007096.BAGW01000018_gene660	4.785e-06	48.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,2N6XA@216572|Oscillospiraceae	186801|Clostridia	V	MacB-like periplasmic core domain	macB1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_9500275_3	1123013.AUIC01000004_gene1752	6.606e-11	64.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	nudE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872	-	ko:K08312	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3067,iE2348C_1286.E2348C_3641,iECABU_c1320.ECABU_c38150,iECED1_1282.ECED1_4056,iECNA114_1301.ECNA114_3494,iECOK1_1307.ECOK1_3810,iECP_1309.ECP_3483,iECS88_1305.ECS88_3783,iECSF_1327.ECSF_3218,iLF82_1304.LF82_1531,iNRG857_1313.NRG857_16815,iUMN146_1321.UM146_17040,iUTI89_1310.UTI89_C3895,ic_1306.c4167	NUDIX
YHH1_k127_9500275_1	340177.Cag_0520	3.529e-26	109.0	COG2929@1|root,COG2929@2|Bacteria,1FFMG@1090|Chlorobi	1090|Chlorobi	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
YHH1_k127_9500275_2	517417.Cpar_0862	8.88e-16	81.0	COG5304@1|root,COG5304@2|Bacteria,1FFGD@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9500275_0	1123013.AUIC01000004_gene1752	1.874e-30	127.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	nudE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872	-	ko:K08312	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3067,iE2348C_1286.E2348C_3641,iECABU_c1320.ECABU_c38150,iECED1_1282.ECED1_4056,iECNA114_1301.ECNA114_3494,iECOK1_1307.ECOK1_3810,iECP_1309.ECP_3483,iECS88_1305.ECS88_3783,iECSF_1327.ECSF_3218,iLF82_1304.LF82_1531,iNRG857_1313.NRG857_16815,iUMN146_1321.UM146_17040,iUTI89_1310.UTI89_C3895,ic_1306.c4167	NUDIX
YHH1_k127_9501933_1	1163671.JAGI01000001_gene373	3.732e-12	73.0	COG4997@1|root,COG4997@2|Bacteria,1VEG6@1239|Firmicutes,24QRF@186801|Clostridia,36KRV@31979|Clostridiaceae	186801|Clostridia	S	phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF429,MazG-like
YHH1_k127_9501933_0	1002367.HMPREF0673_01864	8.963e-51	186.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,2FNPV@200643|Bacteroidia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
YHH1_k127_9503827_0	1236973.JCM9157_1766	1.6e-37	151.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,1ZBX9@1386|Bacillus	91061|Bacilli	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YHH1_k127_9559076_0	702438.HMPREF9431_00782	2.265e-21	100.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH1_k127_9576478_0	1196323.ALKF01000195_gene1955	8.093e-48	191.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,26SD1@186822|Paenibacillaceae	91061|Bacilli	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrB1	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YHH1_k127_9597660_0	446468.Ndas_4542	1.864e-25	113.0	COG1437@1|root,COG1437@2|Bacteria,2GNX6@201174|Actinobacteria,4EPN5@85012|Streptosporangiales	201174|Actinobacteria	F	CYTH domain	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
YHH1_k127_9597660_1	411489.CLOL250_00306	8.718e-12	71.0	2BTP7@1|root,2ZSJS@2|Bacteria,1W3FS@1239|Firmicutes,2570H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9620503_0	679926.Mpet_1045	2.939e-39	150.0	COG3260@1|root,arCOG01553@2157|Archaea,2Y8IV@28890|Euryarchaeota,2NAV7@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM NADH ubiquinone oxidoreductase, 20	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
YHH1_k127_9620503_1	261292.Nit79A3_1609	1.755e-20	104.0	COG0288@1|root,COG0288@2|Bacteria,1MXW3@1224|Proteobacteria,2VP29@28216|Betaproteobacteria,373UI@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Carboxysome Shell Carbonic Anhydrase	-	-	-	-	-	-	-	-	-	-	-	-	CsoSCA
YHH1_k127_9620503_2	1407650.BAUB01000005_gene1267	6.47e-05	52.0	2A0JQ@1|root,2ZFXM@2|Bacteria,1GPCN@1117|Cyanobacteria,1H2WU@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9641582_0	1123393.KB891327_gene442	4.462e-06	61.0	COG0811@1|root,COG0811@2|Bacteria,1N2RJ@1224|Proteobacteria,2VM7W@28216|Betaproteobacteria,1KSAP@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Domain of unknown function (DUF2341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,Laminin_G_3,MotA_ExbB
YHH1_k127_9716169_1	1265505.ATUG01000003_gene873	8.682e-25	113.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2MHZH@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM tyrosine recombinase XerD	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH1_k127_9716169_2	411473.RUMCAL_03120	1.865e-20	96.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3WK6U@541000|Ruminococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
YHH1_k127_9716169_0	1047013.AQSP01000107_gene2079	2.84e-57	207.0	COG1432@1|root,COG1432@2|Bacteria,2NRX6@2323|unclassified Bacteria	2|Bacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
YHH1_k127_9720447_0	765911.Thivi_1200	4.079e-239	745.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1WWB1@135613|Chromatiales	135613|Chromatiales	T	SMART Nucleotide binding protein, PINc	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
YHH1_k127_9720447_1	511051.CSE_06730	1.059e-28	127.0	COG1355@1|root,COG2843@1|root,COG1355@2|Bacteria,COG2843@2|Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	capA	-	1.13.11.16,1.13.11.8	ko:K04101,ko:K05713,ko:K06990,ko:K07282	ko00360,ko00362,ko00624,ko00627,ko01120,ko01220,map00360,map00362,map00624,map00627,map01120,map01220	M00545	R01632,R03550,R04280,R04376,R06788,R09565	RC00233,RC00387,RC00535,RC01140,RC01364,RC02567,RC02694	br01602,ko00000,ko00001,ko00002,ko01000,ko04812	-	-	-	LigB,Memo,PGA_cap
YHH1_k127_9770776_1	1304284.L21TH_2688	2.312e-29	119.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,36E5N@31979|Clostridiaceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH1_k127_9770776_0	330779.Saci_1388	1.559e-60	218.0	COG0396@1|root,arCOG04236@2157|Archaea,2XQ7X@28889|Crenarchaeota	28889|Crenarchaeota	O	TIGRFAM FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
YHH1_k127_9770776_2	1298865.H978DRAFT_0173	7.694e-05	53.0	COG3420@1|root,COG3420@2|Bacteria,1R2DB@1224|Proteobacteria,1RY2Y@1236|Gammaproteobacteria,4642E@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Chondroitinase B	aly	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Chondroitinas_B
YHH1_k127_9832678_0	1380390.JIAT01000010_gene4287	1.942e-50	190.0	COG2131@1|root,COG2131@2|Bacteria,2IEBI@201174|Actinobacteria,4CR5J@84995|Rubrobacteria	84995|Rubrobacteria	F	MafB19-like deaminase	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
YHH1_k127_9832678_1	996637.SGM_4117	3.09e-07	55.0	2F6XD@1|root,33ZDE@2|Bacteria,2IMMF@201174|Actinobacteria	201174|Actinobacteria	S	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
YHH1_k127_983831_2	1408254.T458_04995	2.29e-15	83.0	2CDF4@1|root,32RXN@2|Bacteria,1VACE@1239|Firmicutes,4HKM4@91061|Bacilli,26Z77@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1360)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1360
YHH1_k127_983831_1	1094980.Mpsy_1901	6.238e-49	179.0	COG3832@1|root,arCOG05261@2157|Archaea,2Y3Q0@28890|Euryarchaeota	28890|Euryarchaeota	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YHH1_k127_983831_0	1122918.KB907256_gene2237	4.319e-50	184.0	COG3832@1|root,COG3832@2|Bacteria,1V799@1239|Firmicutes,4HHAD@91061|Bacilli,26WTI@186822|Paenibacillaceae	91061|Bacilli	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YHH1_k127_9849036_0	237727.NAP1_07460	1.239e-67	232.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2TQVI@28211|Alphaproteobacteria,2K04N@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YHH1_k127_9849036_2	1411123.JQNH01000001_gene1703	5.396e-47	173.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2TSI8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YHH1_k127_9849036_1	347256.MHO_1450	9.54e-54	192.0	COG0048@1|root,COG0048@2|Bacteria,3WTGE@544448|Tenericutes	544448|Tenericutes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
YHH1_k127_9853023_0	395495.Lcho_0047	2.032e-42	168.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1N58A@1224|Proteobacteria,2VHVP@28216|Betaproteobacteria,1KN51@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	yfhK	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
YHH1_k127_9880451_0	234267.Acid_3784	4e-61	216.0	COG0177@1|root,COG0177@2|Bacteria,3Y3QD@57723|Acidobacteria	57723|Acidobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
YHH1_k127_9891485_1	1122182.KB903838_gene4056	1.28e-07	64.0	COG2133@1|root,COG2133@2|Bacteria,2HEMB@201174|Actinobacteria,4DA70@85008|Micromonosporales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PA14,PKD
YHH1_k127_9891485_0	1382306.JNIM01000001_gene414	6.57e-09	64.0	COG3428@1|root,COG3428@2|Bacteria,2G72V@200795|Chloroflexi	200795|Chloroflexi	K	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
YHH1_k127_9917671_1	86106.I862_04255	3.29e-39	153.0	2AHEN@1|root,317RU@2|Bacteria,1P419@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
YHH1_k127_9917671_0	1286171.EAL2_c12270	3.183e-52	196.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,25V6U@186806|Eubacteriaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YHH1_k127_9938366_0	316274.Haur_1712	3.094e-49	182.0	COG0221@1|root,COG0221@2|Bacteria,2G6T4@200795|Chloroflexi,375J0@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
YHH1_k127_9954056_2	1121448.DGI_0093	1.493e-23	117.0	COG1032@1|root,COG1032@2|Bacteria,1NRWP@1224|Proteobacteria,42S72@68525|delta/epsilon subdivisions,2WNA6@28221|Deltaproteobacteria,2M7RD@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YHH1_k127_9954056_0	1033806.HTIA_0926	3.816e-97	332.0	COG0366@1|root,arCOG02948@2157|Archaea,2XTAY@28890|Euryarchaeota,23UN0@183963|Halobacteria	183963|Halobacteria	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
YHH1_k127_9954056_1	224324.aq_1853	3.224e-44	168.0	COG1994@1|root,COG1994@2|Bacteria,2G44C@200783|Aquificae	200783|Aquificae	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
YHH1_k127_9969744_4	289376.THEYE_A1425	1.549e-13	73.0	COG0361@1|root,COG0361@2|Bacteria,3J0QB@40117|Nitrospirae	40117|Nitrospirae	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
YHH1_k127_9969744_5	518766.Rmar_0865	6.691e-12	65.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
YHH1_k127_9969744_2	1047013.AQSP01000074_gene1890	1.365e-32	130.0	COG0099@1|root,COG0099@2|Bacteria,2NPKH@2323|unclassified Bacteria	2|Bacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YHH1_k127_9969744_1	1159488.SEQMU2_08705	3.941e-33	132.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,4GYX3@90964|Staphylococcaceae	91061|Bacilli	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YHH1_k127_9969744_3	1158338.JNLJ01000001_gene472	2.32e-29	122.0	COG0522@1|root,COG0522@2|Bacteria,2G402@200783|Aquificae	200783|Aquificae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
YHH1_k127_9969744_0	1385511.N783_06550	4.94e-74	261.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,2Y9CY@289201|Pontibacillus	91061|Bacilli	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YHH1_k127_998674_0	331678.Cphamn1_1899	4.123e-94	317.0	COG0449@1|root,COG0449@2|Bacteria,1FEMH@1090|Chlorobi	1090|Chlorobi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YHH1_k127_998674_1	1235797.C816_00152	1.058e-18	87.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,2N7IB@216572|Oscillospiraceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
## 1011 queries scanned
## Total time (seconds): 3.5808396339416504
## Rate: 282.34 q/s