## Wed Dec 17 03:56:29 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/YHH1_bin.56.fa -m mmseqs --itype genome -o YHH1_bin.56 --output_dir /data/result/bins/wyx/egg/YHH1_bin.56 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YHH1_k127_10046673_0	671143.DAMO_2896	6.906e-147	493.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH1_k127_10124586_1	1250006.JHZZ01000001_gene895	5.639e-16	85.0	COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,1I37A@117743|Flavobacteriia,3VX9J@52959|Polaribacter	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_10124586_0	1123376.AUIU01000013_gene1773	1.2e-213	677.0	COG0365@1|root,COG0365@2|Bacteria,3J0BJ@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YHH1_k127_1014728_0	130081.XP_005704680.1	1.574e-133	440.0	COG0469@1|root,KOG2323@2759|Eukaryota	2759|Eukaryota	G	pyruvate kinase activity	-	GO:0000003,GO:0000287,GO:0003006,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006629,GO:0006631,GO:0006633,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009791,GO:0009987,GO:0010035,GO:0010038,GO:0010154,GO:0010431,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0021700,GO:0022414,GO:0030955,GO:0031420,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046686,GO:0046700,GO:0046872,GO:0046939,GO:0048316,GO:0048608,GO:0048609,GO:0048731,GO:0048856,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0061458,GO:0071695,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
YHH1_k127_1014728_1	658659.HMPREF0983_03215	2.112e-98	331.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,3VP9X@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
YHH1_k127_10169582_1	986075.CathTA2_0348	1.741e-68	243.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YHH1_k127_10169582_0	234267.Acid_1665	2.142e-208	666.0	COG0209@1|root,COG0209@2|Bacteria,3Y3Q1@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
YHH1_k127_10438102_4	404589.Anae109_3447	3.005e-05	57.0	2AIXD@1|root,319F1@2|Bacteria,1Q2IM@1224|Proteobacteria,4385A@68525|delta/epsilon subdivisions,2X3FB@28221|Deltaproteobacteria,2YVU7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10438102_8	1254432.SCE1572_38125	0.0004837	53.0	2AIXD@1|root,319F1@2|Bacteria,1Q2IM@1224|Proteobacteria,4385A@68525|delta/epsilon subdivisions,2X3FB@28221|Deltaproteobacteria,2YVU7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10438102_5	1122217.KB899581_gene1623	5.494e-05	56.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,4H4QP@909932|Negativicutes	909932|Negativicutes	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
YHH1_k127_10438102_9	1192034.CAP_2719	0.0008452	52.0	2AIXD@1|root,319F1@2|Bacteria,1Q2IM@1224|Proteobacteria,4385A@68525|delta/epsilon subdivisions,2X3FB@28221|Deltaproteobacteria,2YVU7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10438102_6	1192034.CAP_2719	0.0001216	55.0	2AIXD@1|root,319F1@2|Bacteria,1Q2IM@1224|Proteobacteria,4385A@68525|delta/epsilon subdivisions,2X3FB@28221|Deltaproteobacteria,2YVU7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10438102_1	889378.Spiaf_1349	1.671e-92	313.0	COG1600@1|root,COG1600@2|Bacteria,2JARS@203691|Spirochaetes	203691|Spirochaetes	C	4Fe-4S double cluster binding domain	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
YHH1_k127_10438102_0	525904.Tter_1654	4.182e-126	413.0	COG0216@1|root,COG0216@2|Bacteria,2NNKY@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02835,ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH1_k127_10438102_2	1123371.ATXH01000002_gene318	1.187e-64	235.0	COG2271@1|root,COG2271@2|Bacteria,2GI5W@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH1_k127_10438102_3	1173264.KI913949_gene173	1.667e-17	87.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,VKOR
YHH1_k127_10440509_2	1121912.AUHD01000008_gene46	2.38e-42	159.0	COG0614@1|root,COG0614@2|Bacteria,4NTHD@976|Bacteroidetes,1I4WB@117743|Flavobacteriia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
YHH1_k127_10440509_1	864565.HMPREF0379_1551	4.824e-44	171.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia	186801|Clostridia	M	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Lactamase_B
YHH1_k127_10440509_0	396588.Tgr7_0530	7.175e-134	436.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1WWWF@135613|Chromatiales	135613|Chromatiales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YHH1_k127_10470471_0	1218173.BALCAV_0217110	2.077e-88	302.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1ZBXG@1386|Bacillus	91061|Bacilli	D	COG1192 ATPases involved in chromosome partitioning	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YHH1_k127_10470471_1	350688.Clos_2867	2.823e-06	52.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,36DTS@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YHH1_k127_10479408_0	1168034.FH5T_15090	1.6e-58	215.0	COG0679@1|root,COG0679@2|Bacteria	2|Bacteria	S	auxin-activated signaling pathway	mdcF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.2.3	ko:K00101,ko:K07088,ko:K13936	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000,ko02000	2.A.69.2.1	-	iECW_1372.ECW_m2605,iWFL_1372.ECW_m2605	Mem_trans
YHH1_k127_10479408_1	269799.Gmet_0363	2.523e-07	62.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,43SI8@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH1_k127_10509579_11	95619.PM1_0201670	0.0001653	53.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,1RUSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	N-formylglutamate amidohydrolase	hutG	-	3.5.1.68,3.5.3.8	ko:K01458,ko:K01479	ko00340,ko00630,ko01100,map00340,map00630,map01100	M00045	R00525,R02285	RC00165,RC00221,RC00323,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	FGase
YHH1_k127_10509579_7	545243.BAEV01000004_gene873	1.195e-31	126.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,36KFX@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YHH1_k127_10509579_8	292459.STH3303	1.213e-29	123.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
YHH1_k127_10509579_1	945713.IALB_2926	6.527e-125	403.0	COG0588@1|root,COG0588@2|Bacteria	2|Bacteria	G	phosphoglycerate mutase activity	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
YHH1_k127_10509579_2	515635.Dtur_1131	1.517e-100	340.0	COG0126@1|root,COG0126@2|Bacteria	2|Bacteria	F	phosphoglycerate kinase activity	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSbBS512_1146.SbBS512_E3351	PGK
YHH1_k127_10509579_6	880073.Calab_1805	5.613e-48	178.0	COG1595@1|root,COG1595@2|Bacteria,2NRM3@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_10509579_5	880073.Calab_1806	4.429e-49	184.0	295PX@1|root,2ZT19@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10509579_9	485916.Dtox_0233	5.311e-29	118.0	COG1342@1|root,COG1342@2|Bacteria,1V5RE@1239|Firmicutes,25CFP@186801|Clostridia,262AN@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0251 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
YHH1_k127_10509579_12	485915.Dret_0444	0.0002582	46.0	2AGN7@1|root,316VI@2|Bacteria,1NIHN@1224|Proteobacteria,42XGQ@68525|delta/epsilon subdivisions,2WSYP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Family of unknown function (DUF5320)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5320
YHH1_k127_10509579_3	926569.ANT_16630	5.912e-86	296.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
YHH1_k127_10509579_0	1232410.KI421424_gene1685	4.016e-203	649.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,43RZZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
YHH1_k127_10509579_4	1121011.AUCB01000002_gene533	6.796e-51	198.0	COG0626@1|root,COG0626@2|Bacteria,4NF4W@976|Bacteroidetes,1HWS8@117743|Flavobacteriia,23G3I@178469|Arenibacter	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
YHH1_k127_10509579_10	1286171.EAL2_c06690	2.685e-22	114.0	COG2372@1|root,COG5492@1|root,COG2372@2|Bacteria,COG5492@2|Bacteria,1V17S@1239|Firmicutes,24GRG@186801|Clostridia	186801|Clostridia	N	S-layer domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_5,Cadherin-like,SLH,Transglut_core
YHH1_k127_10655079_0	1089550.ATTH01000001_gene1406	4.884e-65	229.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1FIYJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH1_k127_10731653_2	555779.Dthio_PD2243	2.562e-54	196.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,42N6H@68525|delta/epsilon subdivisions,2WNG7@28221|Deltaproteobacteria,2M9TZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YHH1_k127_10731653_1	570952.ATVH01000016_gene2539	8.477e-73	257.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,2TRD4@28211|Alphaproteobacteria,2JPQD@204441|Rhodospirillales	204441|Rhodospirillales	J	lysyl-tRNA synthetase	poxA	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
YHH1_k127_10731653_0	1215343.B488_06140	5.217e-73	257.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,2TT31@28211|Alphaproteobacteria,4B7QS@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	lysine 2,3-aminomutase	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
YHH1_k127_10731653_3	880073.Calab_3024	1.084e-18	88.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	-	-	-	ko:K11744	-	-	-	-	ko00000	-	-	-	AI-2E_transport
YHH1_k127_10784432_0	1123274.KB899411_gene3072	0.0001013	53.0	COG1378@1|root,COG1378@2|Bacteria	2|Bacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_10849481_0	933262.AXAM01000141_gene2544	2.636e-07	57.0	COG4372@1|root,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_10853386_1	1158345.JNLL01000001_gene236	2.031e-76	264.0	COG1692@1|root,COG1692@2|Bacteria,2G3Y9@200783|Aquificae	200783|Aquificae	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
YHH1_k127_10853386_0	656519.Halsa_1462	1.056e-106	358.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3WA6J@53433|Halanaerobiales	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
YHH1_k127_10853386_3	1444309.JAQG01000095_gene399	4.443e-18	96.0	COG1664@1|root,COG1664@2|Bacteria,1V1NS@1239|Firmicutes,4HGUF@91061|Bacilli	91061|Bacilli	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YHH1_k127_10853386_2	309803.CTN_0200	3.541e-35	137.0	COG0311@1|root,COG0311@2|Bacteria,2GCYX@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
YHH1_k127_10893406_0	1089439.KB902240_gene754	8.789e-143	463.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,46066@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
YHH1_k127_10893406_2	44689.DDB0190849	2.661e-23	106.0	COG0237@1|root,2STE9@2759|Eukaryota,3XC8Z@554915|Amoebozoa	554915|Amoebozoa	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_17
YHH1_k127_10893406_1	1047013.AQSP01000099_gene1493	3.517e-72	247.0	COG2131@1|root,COG2131@2|Bacteria,2NPW9@2323|unclassified Bacteria	2|Bacteria	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
YHH1_k127_1337603_5	525904.Tter_1074	1.951e-21	106.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YHH1_k127_1337603_3	420247.Msm_0612	1.513e-30	131.0	COG0009@1|root,arCOG01952@2157|Archaea,2XVGC@28890|Euryarchaeota,23P1X@183925|Methanobacteria	183925|Methanobacteria	J	Sua5 YciO YrdC YwlC	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
YHH1_k127_1337603_0	1209989.TepiRe1_2130	1.397e-136	441.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,42F8D@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
YHH1_k127_1337603_1	536232.CLM_1754	1.392e-89	305.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,36DD8@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
YHH1_k127_1337603_6	1394178.AWOO02000011_gene3932	5.267e-11	73.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4EIK2@85012|Streptosporangiales	201174|Actinobacteria	M	Sortase family	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
YHH1_k127_1337603_8	1384054.N790_00660	0.0001293	53.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1X4MS@135614|Xanthomonadales	135614|Xanthomonadales	GM	Multidrug MFS transporter	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
YHH1_k127_1337603_2	525904.Tter_0795	5.494e-57	205.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH1_k127_1337603_4	1123368.AUIS01000013_gene826	1.9e-25	108.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,2ND5X@225057|Acidithiobacillales	225057|Acidithiobacillales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
YHH1_k127_1337603_7	1230342.CTM_17377	1.654e-08	61.0	COG1686@1|root,COG1686@2|Bacteria,1V37K@1239|Firmicutes,24HQ3@186801|Clostridia,36IUK@31979|Clostridiaceae	186801|Clostridia	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S11
YHH1_k127_1339580_1	247490.KSU1_A0010	1.426e-52	188.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_24
YHH1_k127_1339580_0	1123226.KB899282_gene2958	2.117e-65	233.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,4HJIJ@91061|Bacilli,26TJZ@186822|Paenibacillaceae	91061|Bacilli	L	Belongs to the 'phage' integrase family	xerD3	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
YHH1_k127_1339580_2	562970.Btus_1039	1.994e-34	137.0	COG0596@1|root,COG0596@2|Bacteria,1VRHA@1239|Firmicutes,4IQ6T@91061|Bacilli,278RD@186823|Alicyclobacillaceae	91061|Bacilli	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
YHH1_k127_1379058_1	481448.Minf_1632	3.489e-16	82.0	COG0613@1|root,COG0707@1|root,COG0613@2|Bacteria,COG0707@2|Bacteria,46SK7@74201|Verrucomicrobia,37FWH@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glyco_trans_1_4,MGDG_synth
YHH1_k127_1379058_2	1382306.JNIM01000001_gene1052	7.19e-14	78.0	COG0297@1|root,COG0297@2|Bacteria,2G60C@200795|Chloroflexi	200795|Chloroflexi	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
YHH1_k127_1379058_0	345219.Bcoa_2523	7.096e-48	177.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,1ZB6Y@1386|Bacillus	91061|Bacilli	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
YHH1_k127_1398852_0	1121468.AUBR01000008_gene2055	1.903e-59	214.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,42FAT@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
YHH1_k127_1398852_1	936140.AEOT01000027_gene894	6.409e-43	161.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,3F65B@33958|Lactobacillaceae	91061|Bacilli	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YHH1_k127_1411444_3	706587.Desti_4421	3.735e-12	66.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2MQ8K@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM MgsA AAA ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
YHH1_k127_1411444_1	1123248.KB893315_gene3105	2.787e-75	259.0	COG4420@1|root,COG4420@2|Bacteria,4NH74@976|Bacteroidetes,1IVP9@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
YHH1_k127_1411444_2	472759.Nhal_2709	3.609e-37	152.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
YHH1_k127_1411444_0	387092.NIS_0272	1.266e-288	901.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YHH1_k127_1421838_0	156978.CIMIT_05860	2.417e-218	692.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,22KA8@1653|Corynebacteriaceae	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH1_k127_1421838_1	313628.LNTAR_01055	9.956e-83	284.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria	2|Bacteria	F	GMP synthase (glutamine-hydrolyzing) activity	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	GATase,GMP_synt_C,NAD_synthase
YHH1_k127_1425248_0	555088.DealDRAFT_1177	1.375e-240	762.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,42KC8@68298|Syntrophomonadaceae	186801|Clostridia	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
YHH1_k127_1425248_1	710243.XP_007598796.1	0.0004463	51.0	COG4992@1|root,KOG1402@2759|Eukaryota,38EEM@33154|Opisthokonta,3NUZV@4751|Fungi,3QK3A@4890|Ascomycota,213Z6@147550|Sordariomycetes,1ETSQ@1028384|Glomerellales	4751|Fungi	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	CAR2	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006560,GO:0006591,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0010121,GO:0016054,GO:0016740,GO:0016769,GO:0019493,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	iMM904.YLR438W,iND750.YLR438W	Aminotran_3
YHH1_k127_1443692_1	1134912.AJTV01000046_gene3472	7.755e-51	186.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2TRNR@28211|Alphaproteobacteria,36X3C@31993|Methylocystaceae	28211|Alphaproteobacteria	IM	LytB protein	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
YHH1_k127_1443692_2	716544.wcw_0886	1.797e-10	67.0	2ENBK@1|root,314CD@2|Bacteria,2JGHU@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1443692_0	1227268.HMPREF1552_01821	4.069e-136	452.0	COG0018@1|root,COG0018@2|Bacteria,378C4@32066|Fusobacteria	32066|Fusobacteria	J	Psort location Cytoplasmic, score 9.97	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YHH1_k127_1477162_10	644966.Tmar_0363	2.535e-09	59.0	COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,24AMP@186801|Clostridia,3WDCW@538999|Clostridiales incertae sedis	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
YHH1_k127_1477162_5	981327.F925_01328	5.759e-14	81.0	COG3545@1|root,COG3545@2|Bacteria,1RKTI@1224|Proteobacteria,1S66T@1236|Gammaproteobacteria,3NKFF@468|Moraxellaceae	1236|Gammaproteobacteria	S	Serine hydrolase	ydeN	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
YHH1_k127_1477162_1	999411.HMPREF1092_02741	5.604e-29	122.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,36I0G@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
YHH1_k127_1477162_12	1121439.dsat_2904	0.0004827	43.0	2AZ0G@1|root,31R6J@2|Bacteria,1NMSQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1477162_6	525255.HMPREF0077_1527	5.268e-12	69.0	2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,25HQ1@186801|Clostridia	186801|Clostridia	S	COG NOG38524 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1477162_4	211165.AJLN01000021_gene2775	3.97e-14	75.0	2A7FA@1|root,30WCV@2|Bacteria,1GFDD@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1477162_7	886379.AEWI01000053_gene2706	7.721e-12	69.0	2B2PH@1|root,31V97@2|Bacteria,4P7QK@976|Bacteroidetes,2FZV0@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1477162_9	632245.CLP_4083	1.987e-10	65.0	2ED6K@1|root,3373A@2|Bacteria,1VI2S@1239|Firmicutes,24QZV@186801|Clostridia,36TJ8@31979|Clostridiaceae	186801|Clostridia	S	the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1477162_3	643473.KB235930_gene2643	4.412e-16	79.0	2B9ZZ@1|root,323DM@2|Bacteria,1GEQP@1117|Cyanobacteria	1117|Cyanobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1477162_2	1268240.ATFI01000022_gene172	8.03e-26	106.0	2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,2FPSJ@200643|Bacteroidia,4AQ6V@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1477162_8	1121447.JONL01000022_gene3720	1.311e-10	62.0	2EPJ6@1|root,33H5U@2|Bacteria	2|Bacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1477162_13	1348908.KI518583_gene2324	0.0008264	43.0	2DR8Z@1|root,33AQV@2|Bacteria,1VK7N@1239|Firmicutes,4HRWZ@91061|Bacilli,1ZISI@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1477162_11	479431.Namu_2274	4.688e-06	59.0	28Z1N@1|root,2ZKU6@2|Bacteria,2I3ND@201174|Actinobacteria,4EVEX@85013|Frankiales	201174|Actinobacteria	-	-	mptB	-	-	ko:K14337,ko:K14339	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	GT87
YHH1_k127_1477162_0	497964.CfE428DRAFT_0761	3.019e-35	149.0	28ID8@1|root,2Z8FH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_167190_1	1121342.AUCO01000021_gene1108	8.665e-63	233.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,36DPA@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
YHH1_k127_167190_0	880073.Calab_0503	4.925e-71	250.0	COG0826@1|root,COG0826@2|Bacteria,2NPQH@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
YHH1_k127_1754912_1	44056.XP_009038109.1	9.073e-08	61.0	2CY44@1|root,2S1W5@2759|Eukaryota	2759|Eukaryota	S	Translin family	-	-	-	-	-	-	-	-	-	-	-	-	Translin
YHH1_k127_1754912_0	1123372.AUIT01000006_gene1380	1.259e-129	434.0	COG0474@1|root,COG0474@2|Bacteria,2GGR5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
YHH1_k127_1771110_0	1121468.AUBR01000026_gene2920	1.314e-155	500.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,42FC2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
YHH1_k127_1771110_1	272562.CA_C0590	1.027e-80	280.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,36DJS@31979|Clostridiaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
YHH1_k127_1843622_2	1121382.JQKG01000094_gene1483	4.719e-20	93.0	COG0847@1|root,COG0847@2|Bacteria,1WJES@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	PAS_8,RNase_T
YHH1_k127_1843622_1	903814.ELI_2479	2.534e-99	343.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,25URA@186806|Eubacteriaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
YHH1_k127_1843622_0	471223.GWCH70_0033	5.966e-142	470.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,1WEZ0@129337|Geobacillus	91061|Bacilli	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
YHH1_k127_1873296_1	926550.CLDAP_26480	3.425e-38	153.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_1873296_2	1120998.AUFC01000021_gene952	1.105e-20	96.0	COG4747@1|root,COG4747@2|Bacteria,1V4AA@1239|Firmicutes,25DMC@186801|Clostridia	186801|Clostridia	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_1873296_0	880073.Calab_2708	1.225e-134	443.0	COG1236@1|root,COG1236@2|Bacteria,2NNVC@2323|unclassified Bacteria	2|Bacteria	J	Beta-Casp domain	-	-	-	ko:K07576,ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
YHH1_k127_1886240_1	246194.CHY_1369	2.265e-62	223.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,42F5T@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM malic	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
YHH1_k127_1886240_0	1382306.JNIM01000001_gene3417	3.224e-206	656.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
YHH1_k127_1943693_3	1224164.B843_08150	0.0001999	50.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,22JQ0@1653|Corynebacteriaceae	201174|Actinobacteria	D	DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YHH1_k127_1943693_1	1304880.JAGB01000005_gene2427	5.216e-136	449.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH1_k127_1943693_0	1499967.BAYZ01000029_gene1212	5.137e-189	599.0	COG0137@1|root,COG0137@2|Bacteria,2NP01@2323|unclassified Bacteria	2|Bacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argG,iSB619.SA_RS04675	Arginosuc_synth
YHH1_k127_1943693_2	243274.THEMA_05295	1.125e-116	384.0	COG0165@1|root,COG0165@2|Bacteria,2GDVX@200918|Thermotogae	200918|Thermotogae	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
YHH1_k127_2022016_2	45157.CMV098CT	7.97e-11	71.0	COG0305@1|root,2QRXQ@2759|Eukaryota	2759|Eukaryota	L	DnaB-like helicase C terminal domain	dnaB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	DnaB,DnaB_C
YHH1_k127_2022016_3	1047171.Mycgr3P62547	1.662e-10	70.0	2E4VG@1|root,2SBQF@2759|Eukaryota,3ABVC@33154|Opisthokonta,3P932@4751|Fungi,3QZTJ@4890|Ascomycota,205UQ@147541|Dothideomycetes	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2022016_1	1484157.PSNIH2_13405	6.239e-25	109.0	2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,1SF0N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2022016_0	1217705.F900_00702	4.819e-25	111.0	COG1783@1|root,COG4373@1|root,COG1783@2|Bacteria,COG4373@2|Bacteria,1R6J1@1224|Proteobacteria,1RS5V@1236|Gammaproteobacteria,3NKDE@468|Moraxellaceae	1236|Gammaproteobacteria	S	phage Terminase large subunit	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	-
YHH1_k127_2031988_0	1047013.AQSP01000118_gene1252	1.514e-94	335.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_2098814_0	1408422.JHYF01000008_gene3805	2.54e-07	63.0	COG1657@1|root,COG1657@2|Bacteria,1V69S@1239|Firmicutes,24FFM@186801|Clostridia,36KYJ@31979|Clostridiaceae	186801|Clostridia	I	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,SLH
YHH1_k127_2098814_1	641526.ADIWIN_2542	1.734e-05	57.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
YHH1_k127_2142893_0	1329250.WOSG25_150010	2.527e-164	542.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,4AWJ9@81850|Leuconostocaceae	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YHH1_k127_2185849_0	1348657.M622_05050	5.173e-48	183.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2VH0E@28216|Betaproteobacteria,2KYAK@206389|Rhodocyclales	206389|Rhodocyclales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH1_k127_2216352_0	697303.Thewi_1343	9.025e-144	470.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,42F53@68295|Thermoanaerobacterales	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YHH1_k127_2232302_6	1336245.JAGO01000003_gene582	1.041e-05	48.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1XHU9@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
YHH1_k127_2232302_5	1262914.BN533_00736	2.584e-30	123.0	COG0720@1|root,COG0720@2|Bacteria,1VAJX@1239|Firmicutes,4H61W@909932|Negativicutes	909932|Negativicutes	H	synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
YHH1_k127_2232302_3	632518.Calow_0149	7.069e-36	141.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,42GWU@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
YHH1_k127_2232302_1	556267.HWAG_01422	1.425e-64	226.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,42N1U@68525|delta/epsilon subdivisions,2YMVV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0928	GTP_cyclohydroI
YHH1_k127_2232302_2	1145276.T479_00485	1.432e-58	208.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,3IWA6@400634|Lysinibacillus	91061|Bacilli	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	pabA	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85	ko:K01664	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	iYO844.BSU00750	GATase
YHH1_k127_2232302_0	272563.CD630_14460	6.498e-78	275.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,25QW7@186804|Peptostreptococcaceae	186801|Clostridia	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
YHH1_k127_2232302_4	1173027.Mic7113_3518	2.388e-32	136.0	COG0115@1|root,COG0115@2|Bacteria,1G8CI@1117|Cyanobacteria	1117|Cyanobacteria	H	PFAM aminotransferase, class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YHH1_k127_2271115_2	103733.JNYO01000014_gene3667	9.356e-08	60.0	COG2172@1|root,COG2172@2|Bacteria,2IKM9@201174|Actinobacteria,4E66E@85010|Pseudonocardiales	201174|Actinobacteria	T	Anti-sigma regulatory factor (Ser Thr protein kinase)	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2,Sigma70_r2
YHH1_k127_2271115_0	172088.AUGA01000038_gene3761	1.796e-85	292.0	COG1013@1|root,COG1013@2|Bacteria,1PJGB@1224|Proteobacteria,2V6K0@28211|Alphaproteobacteria,3K3IQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PFO_beta_C
YHH1_k127_2271115_1	172088.AUGA01000038_gene3762	5.874e-34	137.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,3JUZI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
YHH1_k127_2290442_4	1089549.AZUQ01000001_gene702	2.36e-16	83.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,4EYFQ@85014|Glycomycetales	201174|Actinobacteria	K	ECF sigma factor	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH1_k127_2290442_0	1410668.JNKC01000001_gene1270	1.061e-64	228.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,36DDR@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
YHH1_k127_2290442_3	479434.Sthe_2006	1.023e-25	112.0	COG0432@1|root,COG1304@1|root,COG0432@2|Bacteria,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
YHH1_k127_2290442_1	1462527.CCDM010000003_gene4102	1.389e-52	201.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,23JNG@182709|Oceanobacillus	91061|Bacilli	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YHH1_k127_2290442_6	269800.Tfu_0265	0.0005852	48.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	spoIIAB	GO:0000003,GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757,ko:K06379	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
YHH1_k127_2290442_5	1306990.BARG01000079_gene8166	3.005e-06	54.0	COG1366@1|root,COG1366@2|Bacteria,2IQCB@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS_2
YHH1_k127_2290442_2	673862.BABL1_257	2.227e-29	130.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73	ko:K00852,ko:K00856,ko:K10710,ko:K22026	ko00030,ko00230,ko00240,ko01100,map00030,map00230,map00240,map01100	-	R00185,R00513,R01051,R01131,R01228,R02750,R08124	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH1_k127_2457180_3	247490.KSU1_B0182	1.724e-53	198.0	COG0812@1|root,COG0812@2|Bacteria,2IYGQ@203682|Planctomycetes	203682|Planctomycetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
YHH1_k127_2457180_1	875454.BAEW01000007_gene1143	6.432e-101	344.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,22GGH@1570339|Peptoniphilaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
YHH1_k127_2457180_2	1321784.HMPREF1987_00644	1.299e-54	203.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
YHH1_k127_2457180_4	1408322.JHYK01000011_gene368	7.028e-06	58.0	COG2339@1|root,COG2339@2|Bacteria,1V2VB@1239|Firmicutes,25CPG@186801|Clostridia	186801|Clostridia	S	Protease prsW family	prsW	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
YHH1_k127_2457180_0	234267.Acid_4151	8.825e-138	446.0	COG0841@1|root,COG0841@2|Bacteria,3Y2SK@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH1_k127_2543191_0	429009.Adeg_2059	4.206e-168	544.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,42EN9@68295|Thermoanaerobacterales	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YHH1_k127_2543191_1	1033739.CAEU01000016_gene2186	9.655e-103	346.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,26EBT@186818|Planococcaceae	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH1_k127_2554083_4	398512.JQKC01000008_gene968	1.606e-47	174.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
YHH1_k127_2554083_2	927658.AJUM01000022_gene1216	2.946e-98	327.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,2FQF3@200643|Bacteroidia,3XIIG@558415|Marinilabiliaceae	976|Bacteroidetes	P	ZIP Zinc transporter	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
YHH1_k127_2554083_0	273068.TTE0533	2.758e-110	366.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,42FNN@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Aspartate glutamate uridylate kinase	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YHH1_k127_2554083_3	1449063.JMLS01000007_gene3551	7.356e-68	242.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4HW10@91061|Bacilli,2726X@186822|Paenibacillaceae	91061|Bacilli	E	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain	-	-	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
YHH1_k127_2554083_5	1547445.LO80_02210	1.131e-21	100.0	COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,1S7RK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_2676956_3	880073.Calab_1872	0.0004037	52.0	COG3630@1|root,COG5337@1|root,COG3630@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD,OAD_gamma
YHH1_k127_2676956_1	525318.HMPREF0497_2825	4.051e-75	267.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,3F3P2@33958|Lactobacillaceae	91061|Bacilli	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
YHH1_k127_2676956_0	525904.Tter_0906	1.371e-162	527.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K06400,ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH1_k127_2676956_2	748449.Halha_0693	3.196e-49	190.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WAGW@53433|Halanaerobiales	186801|Clostridia	M	PDZ domain (Also known as DHR or GLGF)	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
YHH1_k127_2763627_6	247490.KSU1_A0010	2.454e-29	119.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_24
YHH1_k127_2763627_4	1173022.Cri9333_0319	5.447e-36	142.0	COG0454@1|root,COG0456@2|Bacteria,1G5V9@1117|Cyanobacteria,1HD8M@1150|Oscillatoriales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
YHH1_k127_2763627_0	391009.Tmel_1300	5.455e-134	445.0	COG0733@1|root,COG0733@2|Bacteria,2GD22@200918|Thermotogae	200918|Thermotogae	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
YHH1_k127_2763627_1	1163730.FFONT_1065	2.485e-65	231.0	COG1028@1|root,arCOG01259@2157|Archaea,2XQE9@28889|Crenarchaeota	28889|Crenarchaeota	I	PFAM short chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH1_k127_2763627_5	941449.dsx2_0868	3.512e-31	128.0	COG3042@1|root,COG3042@2|Bacteria	2|Bacteria	-	-	ydbJ	-	-	ko:K09712,ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	DUF333
YHH1_k127_2763627_3	945713.IALB_1077	9.957e-46	170.0	COG1970@1|root,COG1970@2|Bacteria	2|Bacteria	M	mechanosensitive ion channel activity	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
YHH1_k127_2763627_7	706587.Desti_3809	5.146e-21	98.0	COG0295@1|root,COG0295@2|Bacteria	2|Bacteria	F	cytidine deaminase activity	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
YHH1_k127_2763627_8	686340.Metal_3606	2.007e-07	55.0	2AVB7@1|root,31M2H@2|Bacteria,1QIXN@1224|Proteobacteria,1TGU2@1236|Gammaproteobacteria,1XGP7@135618|Methylococcales	135618|Methylococcales	S	Fuseless	-	-	-	-	-	-	-	-	-	-	-	-	Fuseless
YHH1_k127_2763627_2	647113.Metok_1254	1.181e-46	175.0	COG0474@1|root,arCOG01578@2157|Archaea,2XT4B@28890|Euryarchaeota,23QDK@183939|Methanococci	183939|Methanococci	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
YHH1_k127_2784264_2	273075.Ta0848	0.0003677	49.0	COG1956@1|root,arCOG05374@2157|Archaea,2Y497@28890|Euryarchaeota,242AW@183967|Thermoplasmata	183967|Thermoplasmata	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
YHH1_k127_2784264_0	351627.Csac_0456	5.791e-25	111.0	COG1595@1|root,COG1595@2|Bacteria,1VD37@1239|Firmicutes,25BCE@186801|Clostridia,42GC3@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YHH1_k127_2784264_1	1469948.JPNB01000002_gene3613	1.503e-13	84.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,36F1J@31979|Clostridiaceae	186801|Clostridia	M	YD repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD,RHS_repeat
YHH1_k127_2788893_1	1410632.JHWW01000002_gene2090	1.344e-90	306.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,27JDT@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
YHH1_k127_2788893_0	374847.Kcr_0452	2.863e-115	385.0	COG1373@1|root,arCOG03167@2157|Archaea	2157|Archaea	S	ATPase, AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH1_k127_287221_0	1408422.JHYF01000003_gene872	0.0	1200.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,36E0I@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH1_k127_287221_2	883096.HMPREF9699_01614	3.545e-17	86.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH1_k127_287221_1	1121396.KB893075_gene673	4.225e-21	105.0	COG0642@1|root,COG3437@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2MN4D@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg,SBP_bac_3
YHH1_k127_2928397_0	1033743.CAES01000043_gene450	3.381e-82	283.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,26R0P@186822|Paenibacillaceae	91061|Bacilli	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
YHH1_k127_2928397_1	574087.Acear_0285	1.787e-68	255.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,3WA5T@53433|Halanaerobiales	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
YHH1_k127_2928397_2	1123372.AUIT01000008_gene592	1.273e-14	76.0	COG0054@1|root,COG0054@2|Bacteria,2GHKC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
YHH1_k127_2987748_0	1178540.BA70_08610	1.148e-211	669.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,1ZBFI@1386|Bacillus	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH1_k127_2987748_1	1416759.AYMR01000020_gene26	2.652e-54	199.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4FK45@85023|Microbacteriaceae	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
YHH1_k127_2991118_1	113355.CM001775_gene2388	1.364e-11	68.0	COG3041@1|root,COG3041@2|Bacteria,1G7XK@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM Addiction module toxin, RelE StbE	-	-	-	-	-	-	-	-	-	-	-	-	YafQ_toxin
YHH1_k127_2991118_0	986075.CathTA2_0556	1.632e-208	671.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YHH1_k127_2991118_3	1485545.JQLW01000005_gene1210	6.789e-05	49.0	COG0762@1|root,COG0762@2|Bacteria	2|Bacteria	D	integral membrane protein	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
YHH1_k127_2991118_2	1123508.JH636447_gene7821	2.8e-06	60.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
YHH1_k127_3073522_0	1487953.JMKF01000011_gene5924	8.956e-196	625.0	COG0481@1|root,COG0481@2|Bacteria,1G1AS@1117|Cyanobacteria,1H71B@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Elongation factor Tu domain 2	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YHH1_k127_3101211_2	1128398.Curi_c14280	1.432e-51	192.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,267QA@186813|unclassified Clostridiales	186801|Clostridia	J	S4 RNA-binding domain	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH1_k127_3101211_0	941824.TCEL_00932	3.454e-178	582.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,36EUE@31979|Clostridiaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YHH1_k127_3101211_1	479433.Caci_4080	2.187e-107	375.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
YHH1_k127_3148019_3	309807.SRU_2062	2.241e-31	137.0	COG2202@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,4PM6B@976|Bacteroidetes,1FIJK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH1_k127_3148019_0	1033734.CAET01000069_gene2343	5.419e-81	285.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,1ZB8Q@1386|Bacillus	91061|Bacilli	J	ribosomal protein S12 methylthiotransferase	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YHH1_k127_3148019_2	926550.CLDAP_04380	7.967e-47	183.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
YHH1_k127_3148019_1	926561.KB900621_gene2788	8.249e-51	183.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3WA68@53433|Halanaerobiales	186801|Clostridia	F	TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS04230	AICARFT_IMPCHas,MGS
YHH1_k127_31774_0	1303518.CCALI_01884	6.288e-116	384.0	COG0821@1|root,COG0821@2|Bacteria	2|Bacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iHN637.CLJU_RS06430,iIT341.HP0625,iJN678.gcpE,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037	GcpE
YHH1_k127_31774_8	1124780.ANNU01000017_gene1960	8.232e-20	91.0	COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes,47RW5@768503|Cytophagia	976|Bacteroidetes	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YHH1_k127_31774_4	1227268.HMPREF1552_01884	5.972e-90	310.0	COG0695@1|root,COG0695@2|Bacteria,37BQC@32066|Fusobacteria	32066|Fusobacteria	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
YHH1_k127_31774_9	882378.RBRH_00344	2.799e-06	53.0	COG2155@1|root,COG2155@2|Bacteria,1N77I@1224|Proteobacteria,2VVTM@28216|Betaproteobacteria,1KF0G@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
YHH1_k127_31774_1	926569.ANT_01870	3.988e-115	380.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
YHH1_k127_31774_3	573061.Clocel_3000	5.374e-99	338.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,36E1H@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
YHH1_k127_31774_7	330214.NIDE0447	8.782e-22	111.0	COG0703@1|root,COG0703@2|Bacteria,3J0R8@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
YHH1_k127_31774_5	247490.KSU1_D0666	2.808e-58	224.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,2IXKU@203682|Planctomycetes	203682|Planctomycetes	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroD	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
YHH1_k127_31774_2	1379858.N508_02057	6.676e-107	355.0	COG0082@1|root,COG0082@2|Bacteria,2GETE@200930|Deferribacteres	200930|Deferribacteres	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
YHH1_k127_31774_10	406817.XNC1_1275	0.0002392	47.0	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1MVUT@1224|Proteobacteria,1RQB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	T-protein	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	1.3.1.12,5.4.99.5	ko:K04517,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R01715,R01728	RC00125,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_2925	ACT,CM_2,PDH
YHH1_k127_31774_6	410358.Mlab_0599	8.625e-47	176.0	COG0722@1|root,arCOG00245@2157|Archaea,2XU8C@28890|Euryarchaeota,2N9HG@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
YHH1_k127_327192_2	156889.Mmc1_0450	1.372e-27	116.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TS80@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
YHH1_k127_327192_0	889378.Spiaf_2235	8.561e-237	745.0	COG0013@1|root,COG0013@2|Bacteria,2J5G2@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YHH1_k127_327192_1	926561.KB900622_gene690	8.588e-35	139.0	COG0849@1|root,COG0849@2|Bacteria,1UD79@1239|Firmicutes,25HUK@186801|Clostridia,3WBK1@53433|Halanaerobiales	186801|Clostridia	D	Cell division protein FtsA	-	-	-	-	-	-	-	-	-	-	-	-	FtsA
YHH1_k127_3321943_1	644548.SCNU_05796	3.264e-19	93.0	COG0597@1|root,COG0597@2|Bacteria,2ISAR@201174|Actinobacteria,4GCJT@85026|Gordoniaceae	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
YHH1_k127_3321943_0	765420.OSCT_2780	4.189e-75	269.0	COG0772@1|root,COG0772@2|Bacteria,2G5MQ@200795|Chloroflexi,374RW@32061|Chloroflexia	32061|Chloroflexia	D	TIGRFAM cell division protein FtsW	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
YHH1_k127_3321943_2	748449.Halha_1865	4.394e-07	53.0	COG0328@1|root,COG0328@2|Bacteria,1VAJW@1239|Firmicutes,24NJ8@186801|Clostridia	186801|Clostridia	L	PFAM ribonuclease H	rnhA	-	3.1.26.4	ko:K03469,ko:K06864	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
YHH1_k127_3328977_1	868864.Dester_0074	1.618e-52	194.0	COG0758@1|root,COG0758@2|Bacteria,2G3ZI@200783|Aquificae	200783|Aquificae	LU	DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
YHH1_k127_3328977_2	638302.HMPREF0908_1970	1.425e-34	147.0	COG0726@1|root,COG0726@2|Bacteria,1U25I@1239|Firmicutes,4H25P@909932|Negativicutes	909932|Negativicutes	G	Polysaccharide deacetylase	pgaB_2	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
YHH1_k127_3328977_0	941824.TCEL_01667	6.322e-69	253.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,36FH2@31979|Clostridiaceae	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN,Polysacc_synt_C
YHH1_k127_3345935_0	1122947.FR7_1917	1.04e-80	284.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4H2H6@909932|Negativicutes	909932|Negativicutes	V	Efflux ABC transporter permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH1_k127_3345935_1	946077.W5A_05858	1.743e-75	259.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH1_k127_3345935_2	1044.EH31_14030	1.701e-09	71.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2U139@28211|Alphaproteobacteria,2K18J@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YHH1_k127_3345935_3	1121481.AUAS01000001_gene4582	3.048e-06	60.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,47JF4@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
YHH1_k127_3415963_0	932678.THERU_03335	1.13e-70	252.0	COG2262@1|root,COG2262@2|Bacteria,2G3IR@200783|Aquificae	200783|Aquificae	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YHH1_k127_3475985_1	246197.MXAN_7154	1.251e-33	132.0	COG0412@1|root,COG0412@2|Bacteria,1QVEZ@1224|Proteobacteria	1224|Proteobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
YHH1_k127_3475985_0	653733.Selin_2521	1.389e-97	329.0	COG1194@1|root,COG1194@2|Bacteria	2|Bacteria	L	base-excision repair	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
YHH1_k127_3475985_2	1120956.JHZK01000045_gene1826	2.951e-11	63.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,1JP3Q@119043|Rhodobiaceae	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
YHH1_k127_3495901_1	694427.Palpr_0839	0.0003911	55.0	COG2885@1|root,COG2885@2|Bacteria,4PMJV@976|Bacteroidetes,2G0E0@200643|Bacteroidia,2325J@171551|Porphyromonadaceae	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_3495901_0	1457250.BBMO01000001_gene1581	7.904e-44	187.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
YHH1_k127_3542313_0	1089553.Tph_c04910	8.481e-58	212.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,42ET0@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
YHH1_k127_3564154_0	56780.SYN_01953	1.809e-67	237.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH1_k127_3564154_1	945713.IALB_2603	9.989e-64	239.0	COG2202@1|root,COG3829@1|root,COG4585@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Pkinase,Response_reg
YHH1_k127_3786928_1	373903.Hore_02460	2.539e-49	179.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3WAPJ@53433|Halanaerobiales	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YHH1_k127_3786928_2	485913.Krac_12497	5.9e-35	138.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
YHH1_k127_3786928_0	1408303.JNJJ01000001_gene3736	1.335e-68	239.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1ZD4X@1386|Bacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
YHH1_k127_3790265_0	644282.Deba_2437	9.201e-56	198.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YHH1_k127_3790265_4	1292035.H476_3572	9.819e-05	55.0	COG4099@1|root,COG4099@2|Bacteria	2|Bacteria	F	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SLH
YHH1_k127_3790265_3	1249975.JQLP01000003_gene76	6.113e-06	59.0	COG1361@1|root,COG3266@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,4NMB8@976|Bacteroidetes,1HZAG@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
YHH1_k127_3790265_1	880074.BARVI_02185	2.547e-29	123.0	COG0212@1|root,COG0212@2|Bacteria,4NQRG@976|Bacteroidetes,2FQQB@200643|Bacteroidia,22Y6E@171551|Porphyromonadaceae	976|Bacteroidetes	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
YHH1_k127_3790265_2	1033810.HLPCO_001608	3.781e-12	76.0	COG2812@1|root,COG2812@2|Bacteria,2NNK7@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
YHH1_k127_3813233_2	574087.Acear_0048	8.96e-21	94.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia	186801|Clostridia	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH1_k127_3813233_1	255470.cbdbA669	1.164e-47	178.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi,34CIK@301297|Dehalococcoidia	301297|Dehalococcoidia	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
YHH1_k127_3813233_0	1304880.JAGB01000002_gene1856	6.835e-121	398.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YHH1_k127_3823181_0	1121448.DGI_2687	8.711e-118	405.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2M8QJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
YHH1_k127_3823181_1	760011.Spico_0861	2.794e-38	147.0	COG0041@1|root,COG0041@2|Bacteria,2J96B@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YHH1_k127_3823181_2	1122975.AQVC01000011_gene753	5.31e-11	63.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,2FMYF@200643|Bacteroidia,22X1N@171551|Porphyromonadaceae	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
YHH1_k127_3855294_0	573413.Spirs_2408	3.76e-21	96.0	COG2348@1|root,COG2348@2|Bacteria,2J58H@203691|Spirochaetes	203691|Spirochaetes	V	Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
YHH1_k127_3867489_1	1313292.BCO_0081400	1.784e-56	199.0	COG0148@1|root,COG0148@2|Bacteria,2J59Y@203691|Spirochaetes	203691|Spirochaetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
YHH1_k127_3867489_0	698758.AXY_12660	2.132e-160	516.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YHH1_k127_3867489_2	1122621.ATZA01000012_gene3178	1.686e-19	93.0	COG0614@1|root,COG0614@2|Bacteria,4NQ88@976|Bacteroidetes,1IT7V@117747|Sphingobacteriia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
YHH1_k127_3914754_0	572480.Arnit_2962	8.374e-252	800.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2YMH2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
YHH1_k127_3914754_4	511437.Lbuc_1686	7.783e-15	78.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,3F7XB@33958|Lactobacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
YHH1_k127_3914754_1	269799.Gmet_0075	9.672e-173	554.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,43TFF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH1_k127_3914754_3	43759.JNWK01000050_gene8175	4.775e-59	212.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria	201174|Actinobacteria	D	cell division ATP-binding protein FtsE	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
YHH1_k127_3914754_2	1408823.AXUS01000015_gene1457	2.467e-101	339.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,25QSV@186804|Peptostreptococcaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
YHH1_k127_3939706_2	237368.SCABRO_01858	9.171e-66	229.0	COG1225@1|root,COG1225@2|Bacteria,2IYHT@203682|Planctomycetes	203682|Planctomycetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH1_k127_3939706_0	665571.STHERM_c15920	6.054e-317	1010.0	COG0060@1|root,COG0060@2|Bacteria,2J57V@203691|Spirochaetes	203691|Spirochaetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YHH1_k127_3939706_3	1242864.D187_010064	8.976e-31	139.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YHH1_k127_3939706_1	247490.KSU1_C0123	8.994e-182	577.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	purD	-	6.3.4.13,6.3.5.5	ko:K01945,ko:K01955	ko00230,ko00240,ko00250,ko01100,ko01110,ko01130,map00230,map00240,map00250,map01100,map01110,map01130	M00048,M00051	R00256,R00575,R01395,R04144,R10948,R10949	RC00002,RC00010,RC00043,RC00090,RC00166,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,GARS_A,GARS_C,GARS_N
YHH1_k127_3943960_1	946077.W5A_01920	2.157e-25	109.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	zraR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH1_k127_3943960_0	273068.TTE0640	3.516e-129	429.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,42ERQ@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
YHH1_k127_3957765_3	477974.Daud_1004	2.752e-16	85.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,260BG@186807|Peptococcaceae	186801|Clostridia	E	PFAM peptidase M24	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
YHH1_k127_3957765_2	1047013.AQSP01000085_gene1982	2.611e-25	110.0	COG1430@1|root,COG1430@2|Bacteria,2NQ88@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
YHH1_k127_3957765_0	635013.TherJR_2972	1.338e-129	429.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,260E3@186807|Peptococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
YHH1_k127_3957765_1	1200567.JNKD01000003_gene2142	2.87e-48	177.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1Y3GX@135624|Aeromonadales	135624|Aeromonadales	E	Aminotransferase	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_3969614_2	771875.Ferpe_0015	3.829e-09	71.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2GCKR@200918|Thermotogae	200918|Thermotogae	T	Guanylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
YHH1_k127_3969614_3	324602.Caur_3334	0.000403	54.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	32061|Chloroflexia	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
YHH1_k127_3969614_1	1341151.ASZU01000009_gene896	1.424e-64	231.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,27BNN@186824|Thermoactinomycetaceae	91061|Bacilli	J	Isopentenyl transferase	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YHH1_k127_3969614_0	880073.Calab_2574	1.647e-182	582.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2NNNY@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH1_k127_4023588_0	720554.Clocl_1676	5.499e-53	206.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3WG85@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
YHH1_k127_4023588_2	682795.AciX8_4501	3.569e-05	48.0	arCOG13401@1|root,33MMV@2|Bacteria,3Y5TE@57723|Acidobacteria,2JNR5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
YHH1_k127_4023588_1	1121104.AQXH01000001_gene1933	2.207e-09	68.0	COG0498@1|root,COG0498@2|Bacteria,4NKWI@976|Bacteroidetes,1ITTX@117747|Sphingobacteriia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH1_k127_413789_0	1382356.JQMP01000003_gene2339	1.673e-19	88.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH1_k127_4200466_3	700598.Niako_5416	0.0001475	44.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IW8Y@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH1_k127_4200466_1	436308.Nmar_1658	2.074e-40	158.0	COG1651@1|root,arCOG02868@2157|Archaea	2157|Archaea	O	COG1651 Protein-disulfide isomerase	-	-	-	ko:K21990	-	-	-	-	ko00000	1.A.16.4	-	-	Form_Nir_trans,Thioredoxin_4
YHH1_k127_4200466_0	247490.KSU1_D0406	3.564e-88	306.0	COG0773@1|root,COG0773@2|Bacteria,2IYEH@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_4200466_2	768671.ThimaDRAFT_0740	3.914e-32	133.0	COG1216@1|root,COG1216@2|Bacteria,1N5DV@1224|Proteobacteria,1T4CS@1236|Gammaproteobacteria,1WZQU@135613|Chromatiales	135613|Chromatiales	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_4231572_0	479434.Sthe_1221	6.334e-187	602.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,27XZT@189775|Thermomicrobia	189775|Thermomicrobia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
YHH1_k127_4322254_4	386456.JQKN01000005_gene502	1.988e-37	146.0	COG0463@1|root,arCOG00896@2157|Archaea,2Y7MP@28890|Euryarchaeota,23PZ5@183925|Methanobacteria	183925|Methanobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_4322254_6	573063.Metin_0259	2.568e-08	61.0	COG2456@1|root,arCOG05092@2157|Archaea,2XZCE@28890|Euryarchaeota,23R5T@183939|Methanococci	183939|Methanococci	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
YHH1_k127_4322254_2	1499967.BAYZ01000063_gene6022	8.84e-45	173.0	COG1216@1|root,COG2148@1|root,COG1216@2|Bacteria,COG2148@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	ko:K03606,ko:K07011	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
YHH1_k127_4322254_1	1499680.CCFE01000024_gene2787	1.308e-66	237.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli,1ZC9A@1386|Bacillus	91061|Bacilli	E	L-serine dehydratase	sdaAA	GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
YHH1_k127_4322254_3	574087.Acear_1197	6.518e-43	165.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,3WB9Y@53433|Halanaerobiales	186801|Clostridia	E	TIGRFAM L-serine dehydratase, iron-sulfur-dependent, beta subunit	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
YHH1_k127_4322254_0	439235.Dalk_2221	3.475e-70	259.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH1_k127_4322254_5	386456.JQKN01000002_gene2450	7.824e-20	95.0	COG0438@1|root,arCOG06108@2157|Archaea,2Y8B4@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YHH1_k127_4423874_1	46234.ANA_C20041	8.033e-08	55.0	COG1943@1|root,COG1943@2|Bacteria,1G5Z6@1117|Cyanobacteria,1HU51@1161|Nostocales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_4423874_0	5888.CAK56509	7.21e-80	271.0	COG0104@1|root,KOG1355@2759|Eukaryota,3ZAQQ@5878|Ciliophora	5878|Ciliophora	F	Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first	-	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
YHH1_k127_4428586_3	945550.VISI1226_12886	0.0005022	52.0	COG3291@1|root,COG3291@2|Bacteria,1R3UF@1224|Proteobacteria,1RYBG@1236|Gammaproteobacteria,1XUY1@135623|Vibrionales	135623|Vibrionales	O	Collagenase	-	GO:0005575,GO:0005576	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	PKD,Peptidase_M9,Peptidase_M9_N
YHH1_k127_4428586_2	69014.TK1712	2.739e-15	89.0	COG2244@1|root,arCOG02209@2157|Archaea,2Y1YY@28890|Euryarchaeota,243NK@183968|Thermococci	183968|Thermococci	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
YHH1_k127_4428586_0	309807.SRU_1720	4.596e-82	280.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1FK37@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH1_k127_4428586_1	563040.Saut_0767	1.693e-59	216.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2YMQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YHH1_k127_4602856_0	749222.Nitsa_1088	1.59e-27	116.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2YMEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
YHH1_k127_4683863_1	938288.HG326227_gene436	2.956e-11	76.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,267PP@186813|unclassified Clostridiales	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
YHH1_k127_4683863_0	1236976.JCM16418_2515	4.942e-13	82.0	COG1409@1|root,COG5184@1|root,COG1409@2|Bacteria,COG5184@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	ppe1	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,SLH,fn3
YHH1_k127_4714568_4	1121405.dsmv_1150	9.464e-13	71.0	COG0438@1|root,COG0438@2|Bacteria,1N1RZ@1224|Proteobacteria,42UHY@68525|delta/epsilon subdivisions,2WQD7@28221|Deltaproteobacteria,2MKYI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_4714568_1	1129794.C427_4214	3.859e-94	318.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,1RYY5@1236|Gammaproteobacteria,468EF@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_4714568_2	653948.CCA26087	1.024e-85	295.0	COG1087@1|root,KOG1371@2759|Eukaryota	2759|Eukaryota	M	racemase and epimerase activity, acting on carbohydrates and derivatives	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH1_k127_4714568_0	742727.HMPREF9447_01409	5.763e-160	516.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,2FMZ9@200643|Bacteroidia,4AM97@815|Bacteroidaceae	976|Bacteroidetes	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH1_k127_4714568_6	639283.Snov_4404	2.179e-07	58.0	COG2246@1|root,COG2246@2|Bacteria,1N6ST@1224|Proteobacteria,2UCW9@28211|Alphaproteobacteria,3F02A@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
YHH1_k127_4714568_3	70601.3256436	1.921e-54	198.0	COG0463@1|root,arCOG00894@2157|Archaea,2XWXA@28890|Euryarchaeota,242RY@183968|Thermococci	183968|Thermococci	M	GtrA-like protein	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
YHH1_k127_4714568_5	1121448.DGI_2918	1.108e-09	71.0	COG5542@1|root,COG5542@2|Bacteria,1R6HY@1224|Proteobacteria,43DPW@68525|delta/epsilon subdivisions,2X6SZ@28221|Deltaproteobacteria,2MF9C@213115|Desulfovibrionales	1224|Proteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
YHH1_k127_4736731_0	1047013.AQSP01000140_gene2513	9.341e-41	164.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
YHH1_k127_4736731_1	697281.Mahau_0239	1.372e-24	105.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,42H2T@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
YHH1_k127_4736731_3	504728.K649_02985	3.988e-09	61.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
YHH1_k127_4736731_2	1174504.AJTN02000013_gene3848	1.743e-22	106.0	COG0670@1|root,COG0670@2|Bacteria,1V6RG@1239|Firmicutes,4HISH@91061|Bacilli,1ZCV6@1386|Bacillus	91061|Bacilli	S	Belongs to the BI1 family	yetJ	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
YHH1_k127_4779772_0	1410638.JHXJ01000005_gene2177	2.171e-27	122.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WH5M@541000|Ruminococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH1_k127_4779772_1	1410670.JHXF01000001_gene2632	1.443e-17	87.0	COG2267@1|root,COG2267@2|Bacteria,1TPI0@1239|Firmicutes,247QR@186801|Clostridia,3WIWD@541000|Ruminococcaceae	186801|Clostridia	I	TAP-like protein	-	-	1.11.1.10,3.1.1.24	ko:K00433,ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
YHH1_k127_5066863_0	647113.Metok_0586	2.44e-07	60.0	COG0477@1|root,arCOG00130@2157|Archaea,2XT83@28890|Euryarchaeota,23Q2W@183939|Methanococci	183939|Methanococci	G	PFAM major facilitator superfamily MFS_1	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
YHH1_k127_5066863_1	264732.Moth_1638	5.165e-07	60.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,42EY6@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM VanW family protein	vanW	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
YHH1_k127_5237810_3	1121929.KB898668_gene3366	1.216e-06	50.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,470R9@74385|Gracilibacillus	91061|Bacilli	I	Malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
YHH1_k127_5237810_2	933262.AXAM01000029_gene2731	6.815e-16	84.0	28NQ4@1|root,2ZBPU@2|Bacteria,1RCN1@1224|Proteobacteria,42QPC@68525|delta/epsilon subdivisions,2WMVS@28221|Deltaproteobacteria,2MJR9@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5237810_1	335543.Sfum_1038	4.276e-26	110.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria,2MSGF@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH1_k127_5237810_0	880072.Desac_1155	5.533e-32	132.0	29HYV@1|root,304VW@2|Bacteria,1RDPY@1224|Proteobacteria,42RXW@68525|delta/epsilon subdivisions,2WNTT@28221|Deltaproteobacteria,2MS5G@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5245472_1	635013.TherJR_1549	6.621e-54	201.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,260TU@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH1_k127_5245472_0	1123376.AUIU01000011_gene1076	7.443e-77	269.0	COG0337@1|root,COG0337@2|Bacteria,3J0GA@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
YHH1_k127_5283905_1	1128427.KB904821_gene4286	3.665e-51	185.0	COG0348@1|root,COG0348@2|Bacteria,1GDRT@1117|Cyanobacteria	1117|Cyanobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
YHH1_k127_5283905_0	1114964.L485_03275	9.332e-124	410.0	COG3667@1|root,COG3667@2|Bacteria,1R6TA@1224|Proteobacteria,2U52R@28211|Alphaproteobacteria,2K3M1@204457|Sphingomonadales	204457|Sphingomonadales	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5400502_5	1123228.AUIH01000022_gene3116	6.267e-06	57.0	COG1378@1|root,COG1378@2|Bacteria,1PZ3N@1224|Proteobacteria,1RS6X@1236|Gammaproteobacteria,1XITG@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_5400502_1	865861.AZSU01000002_gene2520	1.8e-48	183.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,36DEP@31979|Clostridiaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YHH1_k127_5400502_0	665571.STHERM_c16030	3.066e-233	735.0	COG0441@1|root,COG0441@2|Bacteria,2J5ID@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
YHH1_k127_5400502_2	1231057.AMGD01000036_gene1667	2.082e-33	150.0	COG1502@1|root,COG1502@2|Bacteria,1VSU5@1239|Firmicutes,4HTP4@91061|Bacilli	91061|Bacilli	I	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,PLDc_2
YHH1_k127_5400502_4	1123277.KB893185_gene3020	3.24e-07	64.0	COG3291@1|root,COG3291@2|Bacteria,4NF7B@976|Bacteroidetes,47MQS@768503|Cytophagia	976|Bacteroidetes	G	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD,RicinB_lectin_2
YHH1_k127_5400502_3	1385510.N781_03850	1.886e-22	114.0	COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,4HHPS@91061|Bacilli,2YA8M@289201|Pontibacillus	91061|Bacilli	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
YHH1_k127_5447333_1	29540.C481_20466	1.702e-05	55.0	arCOG09337@1|root,arCOG09337@2157|Archaea,2Y019@28890|Euryarchaeota,23Y11@183963|Halobacteria	183963|Halobacteria	S	COG3451 Type IV secretory pathway, VirB4 components	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5447333_2	443218.AS9A_2910	0.0005554	51.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,235SS@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
YHH1_k127_5447333_0	313603.FB2170_10106	1.156e-59	226.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
YHH1_k127_5483874_0	502025.Hoch_0986	8.935e-10	72.0	COG0515@1|root,COG0515@2|Bacteria,1P64D@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
YHH1_k127_5543281_9	717606.PaecuDRAFT_1684	1.132e-15	91.0	COG1523@1|root,COG1621@1|root,COG1523@2|Bacteria,COG1621@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,26QXV@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 13 family	pulA2	-	3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	-	R02108,R02111,R02112,R11262	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal
YHH1_k127_5543281_3	3659.XP_004134331.1	8.32e-78	270.0	COG0190@1|root,KOG0089@2759|Eukaryota,37K6Z@33090|Viridiplantae,3GFZP@35493|Streptophyta,4JM5S@91835|fabids	35493|Streptophyta	H	Bifunctional protein	-	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	-	-	-	-	-	-	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
YHH1_k127_5543281_1	391615.ABSJ01000054_gene1424	6.457e-152	498.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1J4HM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iAF1260.b2312,iB21_1397.B21_02197,iBWG_1329.BWG_2086,iECBD_1354.ECBD_1347,iECB_1328.ECB_02237,iECDH10B_1368.ECDH10B_2474,iECDH1ME8569_1439.ECDH1ME8569_2250,iECD_1391.ECD_02237,iECIAI1_1343.ECIAI1_2389,iECO103_1326.ECO103_2776,iECO111_1330.ECO111_3060,iECO26_1355.ECO26_3300,iECW_1372.ECW_m2501,iEKO11_1354.EKO11_1453,iETEC_1333.ETEC_2448,iEcDH1_1363.EcDH1_1344,iEcE24377_1341.EcE24377A_2606,iEcolC_1368.EcolC_1340,iJO1366.b2312,iJR904.b2312,iSF_1195.SF2388,iSFxv_1172.SFxv_2633,iSSON_1240.SSON_2370,iS_1188.S2523,iSbBS512_1146.SbBS512_E2690,iUMNK88_1353.UMNK88_2863,iWFL_1372.ECW_m2501,iY75_1357.Y75_RS12125	GATase_6,GATase_7,Pribosyltran
YHH1_k127_5543281_5	596330.HMPREF0628_1622	1.451e-47	184.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
YHH1_k127_5543281_11	1191523.MROS_1267	1.37e-11	76.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YHH1_k127_5543281_2	1291050.JAGE01000001_gene1471	1.316e-131	434.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3WHD2@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
YHH1_k127_5543281_4	469383.Cwoe_3190	5.237e-65	233.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CR9X@84995|Rubrobacteria	84995|Rubrobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YHH1_k127_5543281_0	1347392.CCEZ01000008_gene2300	5.008e-208	676.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,36DDM@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
YHH1_k127_5543281_8	1211035.CD30_12575	1.173e-19	101.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,4HCJ2@91061|Bacilli,3IVVY@400634|Lysinibacillus	91061|Bacilli	S	Polysaccharide pyruvyl transferase	csaB	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
YHH1_k127_5543281_7	1121024.AUCD01000001_gene1666	6.087e-26	113.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,27GF0@186828|Carnobacteriaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
YHH1_k127_5543281_10	880073.Calab_2790	1.127e-11	72.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
YHH1_k127_5543281_6	1304880.JAGB01000001_gene762	4.529e-39	159.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia	186801|Clostridia	L	DNA polymerase III (delta' subunit)	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
YHH1_k127_5570097_1	537013.CLOSTMETH_00694	6.548e-44	166.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
YHH1_k127_5570097_0	632335.Calkr_1366	1.745e-72	256.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,42F72@68295|Thermoanaerobacterales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH1_k127_562013_0	1123320.KB889668_gene3352	2.409e-48	186.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria	201174|Actinobacteria	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
YHH1_k127_5650705_0	1157632.AQWQ01000004_gene1608	6.66e-16	94.0	COG3227@1|root,COG3227@2|Bacteria,2H48J@201174|Actinobacteria	201174|Actinobacteria	E	Thermolysin metallopeptidase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
YHH1_k127_5650705_3	675817.VDA_000431	0.0001917	56.0	COG1361@1|root,COG1404@1|root,COG2931@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG2931@2|Bacteria,1R59C@1224|Proteobacteria,1SDEC@1236|Gammaproteobacteria,1XWCY@135623|Vibrionales	135623|Vibrionales	MOT	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5650705_2	61459.XP_007784676.1	0.0001917	56.0	KOG3714@1|root,KOG3714@2759|Eukaryota	2759|Eukaryota	O	metalloendopeptidase activity	-	-	3.4.21.7	ko:K01315	ko04080,ko04610,ko05150,ko05164,map04080,map04610,map05150,map05164	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147,ko04516	-	-	-	Astacin,CUB,ShK
YHH1_k127_5650705_1	870187.Thini_1537	7.309e-05	55.0	COG0823@1|root,COG3266@1|root,COG0823@2|Bacteria,COG3266@2|Bacteria,1QXUF@1224|Proteobacteria	1224|Proteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,HYR,VCBS
YHH1_k127_5678515_4	195253.Syn6312_3734	4.646e-12	68.0	COG0454@1|root,COG0456@2|Bacteria,1G1VS@1117|Cyanobacteria,1H2HK@1129|Synechococcus	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH1_k127_5678515_3	1122176.KB903576_gene4944	9.321e-15	76.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1IUBT@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
YHH1_k127_5678515_1	237368.SCABRO_03328	1.11e-47	178.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	MA20_27160	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50
YHH1_k127_5678515_5	391625.PPSIR1_30873	1.263e-08	66.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH1_k127_5678515_2	443144.GM21_0931	9.15e-36	143.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2WPFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
YHH1_k127_5678515_0	112098.XP_008618072.1	3.158e-66	231.0	COG0104@1|root,KOG1355@2759|Eukaryota	2759|Eukaryota	F	adenylosuccinate synthase activity	ADSS	GO:0000166,GO:0001882,GO:0001883,GO:0002376,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003779,GO:0003824,GO:0003924,GO:0004019,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006106,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006520,GO:0006531,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007517,GO:0007519,GO:0008092,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009888,GO:0009987,GO:0010035,GO:0010038,GO:0014706,GO:0014902,GO:0014904,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0017076,GO:0017111,GO:0017144,GO:0018130,GO:0019001,GO:0019438,GO:0019637,GO:0019693,GO:0019725,GO:0019752,GO:0030154,GO:0032501,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042278,GO:0042301,GO:0042451,GO:0042455,GO:0042592,GO:0042692,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043565,GO:0043648,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046686,GO:0046716,GO:0046983,GO:0048046,GO:0048468,GO:0048513,GO:0048731,GO:0048741,GO:0048747,GO:0048856,GO:0048869,GO:0050896,GO:0051015,GO:0051146,GO:0051716,GO:0055001,GO:0055002,GO:0055086,GO:0060249,GO:0060537,GO:0060538,GO:0061061,GO:0061483,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071276,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901657,GO:1901659,GO:1990837	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	iRC1080.CRv4_Au5_s17_g7726_t1	Adenylsucc_synt
YHH1_k127_5853334_1	1385510.N781_08030	8.406e-56	198.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,2YABN@289201|Pontibacillus	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
YHH1_k127_5853334_0	867903.ThesuDRAFT_00546	5.635e-60	217.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3WCHU@538999|Clostridiales incertae sedis	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
YHH1_k127_5853334_2	1380390.JIAT01000011_gene2553	0.00014	47.0	COG0690@1|root,COG0690@2|Bacteria,2HQ1F@201174|Actinobacteria,4CRHK@84995|Rubrobacteria	84995|Rubrobacteria	U	SecE/Sec61-gamma subunits of protein translocation complex	-	-	-	-	-	-	-	-	-	-	-	-	SecE
YHH1_k127_5924979_0	795359.TOPB45_0167	9.852e-74	256.0	COG0081@1|root,COG0081@2|Bacteria,2GH9C@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
YHH1_k127_5924979_1	1382306.JNIM01000001_gene11	8.352e-47	173.0	COG0756@1|root,COG0756@2|Bacteria	2|Bacteria	F	dUTP diphosphatase activity	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23,4.1.1.36,6.3.2.5	ko:K01520,ko:K13038	ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100	M00053,M00120	R02100,R03269,R04231,R11896	RC00002,RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	iYO844.BSU17660	dUTPase
YHH1_k127_5924979_2	1382356.JQMP01000004_gene653	3.777e-26	126.0	COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia	189775|Thermomicrobia	PT	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
YHH1_k127_5924979_4	215803.DB30_2390	5.307e-11	74.0	2AIXD@1|root,319F1@2|Bacteria,1Q2IM@1224|Proteobacteria,4385A@68525|delta/epsilon subdivisions,2X3FB@28221|Deltaproteobacteria,2YVU7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5924979_5	1278073.MYSTI_02278	7.091e-11	73.0	2AIXD@1|root,319F1@2|Bacteria,1Q2IM@1224|Proteobacteria,4385A@68525|delta/epsilon subdivisions,2X3FB@28221|Deltaproteobacteria,2YVU7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_5924979_6	1449126.JQKL01000015_gene2899	0.0001185	49.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
YHH1_k127_5924979_7	1291050.JAGE01000002_gene3865	0.0009135	49.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,3WJJ3@541000|Ruminococcaceae	186801|Clostridia	S	HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
YHH1_k127_5924979_3	255470.cbdbA29	1.654e-17	91.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi,34CYA@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain of unknown function (DUF4131)	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
YHH1_k127_6012087_1	1121930.AQXG01000022_gene42	2.541e-41	153.0	arCOG05874@1|root,2ZJ01@2|Bacteria,4PQ1U@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6012087_9	1150469.RSPPHO_03258	0.0009163	43.0	2B9ZZ@1|root,323DM@2|Bacteria,1MZ6J@1224|Proteobacteria	1224|Proteobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6012087_2	748224.HMPREF9436_00081	3.741e-24	105.0	2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,24K1H@186801|Clostridia,3WJW5@541000|Ruminococcaceae	186801|Clostridia	S	non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6012087_4	1150469.RSPPHO_03279	1.341e-12	68.0	2DTV2@1|root,33MS7@2|Bacteria,1NKAB@1224|Proteobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6012087_8	985867.AEWF01000006_gene498	7.105e-05	46.0	2DI3S@1|root,301Y3@2|Bacteria,1PU5T@1224|Proteobacteria,2V5XM@28211|Alphaproteobacteria,47GES@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6012087_3	211165.AJLN01000021_gene2775	3.223e-13	70.0	2A7FA@1|root,30WCV@2|Bacteria,1GFDD@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6012087_6	1123008.KB905692_gene417	3.016e-10	65.0	2DSTI@1|root,33HD4@2|Bacteria,4NYHV@976|Bacteroidetes,2FZJE@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6012087_7	1203606.HMPREF1526_02587	1.036e-05	48.0	2DPDN@1|root,331NP@2|Bacteria,1VFF8@1239|Firmicutes,24S9D@186801|Clostridia,36VF0@31979|Clostridiaceae	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6012087_0	926550.CLDAP_12040	4.837e-100	344.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
YHH1_k127_6075363_0	453591.Igni_1301	1.355e-33	139.0	COG0180@1|root,arCOG01887@2157|Archaea,2XPK1@28889|Crenarchaeota	28889|Crenarchaeota	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH1_k127_6078997_2	706587.Desti_1066	1.797e-14	77.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
YHH1_k127_6078997_1	643562.Daes_2691	1.547e-14	83.0	2BICI@1|root,32CIM@2|Bacteria,1R1BV@1224|Proteobacteria,43D8J@68525|delta/epsilon subdivisions,2X8F6@28221|Deltaproteobacteria,2MAMC@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6078997_0	445973.CLOBAR_00216	9.535e-55	201.0	293PP@1|root,2ZR5C@2|Bacteria,1VBW4@1239|Firmicutes,24NKJ@186801|Clostridia,25RAV@186804|Peptostreptococcaceae	186801|Clostridia	S	UPF0489 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0489
YHH1_k127_6146225_3	1121405.dsmv_3650	2.431e-15	76.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2WMP6@28221|Deltaproteobacteria,2MHS4@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
YHH1_k127_6146225_1	1121405.dsmv_3651	8.116e-21	97.0	COG0690@1|root,COG0690@2|Bacteria,1Q1BI@1224|Proteobacteria,42X4Z@68525|delta/epsilon subdivisions,2WSQ8@28221|Deltaproteobacteria,2MKUQ@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
YHH1_k127_6146225_2	1232410.KI421428_gene1216	2.134e-20	91.0	COG0267@1|root,COG0267@2|Bacteria,1NJ67@1224|Proteobacteria,42V5X@68525|delta/epsilon subdivisions,2WSIR@28221|Deltaproteobacteria,43VP9@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
YHH1_k127_6146225_0	933262.AXAM01000052_gene1988	5.586e-237	736.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MHTQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH1_k127_6187384_0	1158338.JNLJ01000001_gene302	4.079e-132	436.0	COG0064@1|root,COG0064@2|Bacteria,2G3P7@200783|Aquificae	200783|Aquificae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YHH1_k127_6187384_1	1047013.AQSP01000118_gene1252	2.689e-108	371.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6218092_7	1313304.CALK_1787	2.27e-19	89.0	COG0186@1|root,COG0186@2|Bacteria	2|Bacteria	J	rRNA binding	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
YHH1_k127_6218092_2	1410628.JNKS01000017_gene151	2.599e-50	181.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,27MQ8@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
YHH1_k127_6218092_6	641491.DND132_3411	5.364e-24	104.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2WQ2G@28221|Deltaproteobacteria,2MC5T@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
YHH1_k127_6218092_1	439235.Dalk_1903	1.359e-55	199.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2MJFM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
YHH1_k127_6218092_8	457570.Nther_0207	4.143e-18	85.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
YHH1_k127_6218092_4	519441.Smon_1271	3.426e-26	112.0	COG0096@1|root,COG0096@2|Bacteria,379ZT@32066|Fusobacteria	32066|Fusobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
YHH1_k127_6218092_0	525903.Taci_1169	2.477e-59	213.0	COG0097@1|root,COG0097@2|Bacteria,3TAW4@508458|Synergistetes	508458|Synergistetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
YHH1_k127_6218092_5	748449.Halha_0205	7.082e-25	108.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3WBWI@53433|Halanaerobiales	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
YHH1_k127_6218092_3	518637.EUBIFOR_01035	1.768e-39	152.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,3VQ7N@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
YHH1_k127_6281882_3	866895.HBHAL_4444	3.805e-15	88.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,3NFQS@45667|Halobacillus	91061|Bacilli	M	Subtilase family	-	-	-	ko:K13274,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PPC,Peptidase_S8,SLH
YHH1_k127_6281882_1	1297742.A176_02032	8.554e-26	124.0	COG0402@1|root,COG1506@1|root,COG2885@1|root,COG0402@2|Bacteria,COG1506@2|Bacteria,COG2885@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
YHH1_k127_6281882_0	525904.Tter_1235	3.756e-39	161.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	yueF	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
YHH1_k127_6281882_2	592015.HMPREF1705_00751	2.328e-22	98.0	COG0481@1|root,COG0481@2|Bacteria,3TA5E@508458|Synergistetes	508458|Synergistetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YHH1_k127_6317601_0	66897.DJ64_21720	2.585e-46	174.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
YHH1_k127_6364159_1	981223.AIED01000047_gene1413	6.727e-06	48.0	2AZTC@1|root,31S2K@2|Bacteria,1QPJP@1224|Proteobacteria,1TNA5@1236|Gammaproteobacteria,3NQ8M@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6364159_0	326427.Cagg_3246	7.828e-33	138.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi,375CP@32061|Chloroflexia	32061|Chloroflexia	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
YHH1_k127_6453154_0	580331.Thit_2333	5.703e-229	720.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,42ETB@68295|Thermoanaerobacterales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
YHH1_k127_6453154_1	1031288.AXAA01000009_gene671	1.064e-204	646.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,36DRP@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH1_k127_6453154_2	1354300.AUQY01000005_gene269	2.691e-57	205.0	COG1394@1|root,COG1394@2|Bacteria,1TQ1Y@1239|Firmicutes,247TC@186801|Clostridia,22GBJ@1570339|Peptoniphilaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
YHH1_k127_6453154_3	1278306.KB906934_gene747	8.766e-17	82.0	COG0264@1|root,COG0264@2|Bacteria,378TR@32066|Fusobacteria	32066|Fusobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
YHH1_k127_6526486_1	459349.CLOAM0795	1.388e-10	64.0	COG0042@1|root,COG0042@2|Bacteria,2NP3E@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	ko:K05540,ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
YHH1_k127_6526486_0	273068.TTE0981	3.645e-152	492.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,42F5B@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH1_k127_6530953_2	552811.Dehly_0464	9.93e-09	61.0	COG0718@1|root,COG0718@2|Bacteria,2G77S@200795|Chloroflexi,34DFH@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
YHH1_k127_6530953_1	485913.Krac_6732	2.744e-20	103.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH1_k127_6530953_0	665952.HMPREF1015_02807	1.511e-52	194.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,1ZB78@1386|Bacillus	91061|Bacilli	L	hydrolase, TatD	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YHH1_k127_6530953_3	926692.AZYG01000052_gene1819	5.036e-05	45.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3WA8W@53433|Halanaerobiales	186801|Clostridia	L	TIGRFAM hydrolase, TatD family	yabD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YHH1_k127_6534793_0	350688.Clos_0007	4.975e-210	673.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH1_k127_6534793_3	1444309.JAQG01000097_gene4119	1.94e-18	97.0	COG1649@1|root,COG1649@2|Bacteria,1VF27@1239|Firmicutes,4IQIV@91061|Bacilli	91061|Bacilli	S	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
YHH1_k127_6534793_2	67275.JOAP01000010_gene626	2.251e-20	103.0	COG1595@1|root,COG2340@1|root,COG1595@2|Bacteria,COG2340@2|Bacteria,2GJ21@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Sigma70_r2
YHH1_k127_6534793_1	529709.PYCH_12630	9.201e-60	218.0	COG1208@1|root,arCOG00666@2157|Archaea,2XUA6@28890|Euryarchaeota,2431F@183968|Thermococci	183968|Thermococci	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
YHH1_k127_6534793_4	1449049.JONW01000012_gene52	0.000958	45.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,2KF0Q@204458|Caulobacterales	204458|Caulobacterales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YHH1_k127_6633586_0	1125863.JAFN01000001_gene892	3.796e-149	481.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YHH1_k127_6633586_1	1443122.Z958_02925	2.526e-54	198.0	COG0860@1|root,COG0860@2|Bacteria,1TWQM@1239|Firmicutes,24DKD@186801|Clostridia,36NP0@31979|Clostridiaceae	186801|Clostridia	M	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_2,Amidase_3,Big_5,CW_binding_2,Cu_amine_oxidN1,Glucosaminidase
YHH1_k127_6633586_4	118161.KB235922_gene5081	4.969e-16	83.0	COG0816@1|root,COG0816@2|Bacteria,1G5R5@1117|Cyanobacteria,3VJUT@52604|Pleurocapsales	1117|Cyanobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
YHH1_k127_6633586_3	1304284.L21TH_1916	2.962e-20	96.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,36IT5@31979|Clostridiaceae	186801|Clostridia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
YHH1_k127_6633586_2	357808.RoseRS_0725	7.99e-47	192.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,375DK@32061|Chloroflexia	32061|Chloroflexia	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YHH1_k127_6633586_5	479434.Sthe_1250	0.0006697	45.0	COG1314@1|root,COG1314@2|Bacteria,2G7D9@200795|Chloroflexi,27YMZ@189775|Thermomicrobia	189775|Thermomicrobia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
YHH1_k127_6752587_0	1087481.AGFX01000048_gene2601	1.293e-208	661.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,26QX2@186822|Paenibacillaceae	91061|Bacilli	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YHH1_k127_6752587_1	1111479.AXAR01000009_gene2497	1.962e-29	119.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli	91061|Bacilli	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YHH1_k127_6753801_0	589865.DaAHT2_1454	7.427e-202	633.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MHTQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH1_k127_6753801_6	383372.Rcas_4027	2.903e-36	143.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi,375U3@32061|Chloroflexia	32061|Chloroflexia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
YHH1_k127_6753801_9	1408254.T458_03000	1.66e-19	98.0	COG1649@1|root,COG1649@2|Bacteria,1VF27@1239|Firmicutes	1239|Firmicutes	S	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
YHH1_k127_6753801_10	926569.ANT_03440	1.558e-17	93.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,2G825@200795|Chloroflexi	200795|Chloroflexi	CO	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_6753801_3	443254.Marpi_0880	1.162e-53	195.0	COG0087@1|root,COG0087@2|Bacteria,2GCA1@200918|Thermotogae	200918|Thermotogae	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
YHH1_k127_6753801_5	316274.Haur_4916	1.101e-42	164.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi,374Y7@32061|Chloroflexia	32061|Chloroflexia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YHH1_k127_6753801_11	944480.ATUV01000001_gene1703	7.369e-11	67.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,4375U@68525|delta/epsilon subdivisions,2X23N@28221|Deltaproteobacteria,2M7AW@213113|Desulfurellales	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
YHH1_k127_6753801_1	941824.TCEL_01105	2.773e-105	349.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,36E17@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YHH1_k127_6753801_7	1131269.AQVV01000036_gene1504	1.882e-35	138.0	COG0185@1|root,COG0185@2|Bacteria	2|Bacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
YHH1_k127_6753801_8	469381.Dpep_1941	1.271e-20	97.0	COG0091@1|root,COG0091@2|Bacteria,3TB6W@508458|Synergistetes	508458|Synergistetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
YHH1_k127_6753801_2	1120972.AUMH01000017_gene723	2.926e-71	247.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,2788F@186823|Alicyclobacillaceae	91061|Bacilli	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YHH1_k127_6753801_4	511062.GU3_00920	1.93e-48	176.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,1Y4F9@135624|Aeromonadales	135624|Aeromonadales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
YHH1_k127_6753801_12	500633.CLOHIR_01585	0.0002035	46.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes	1239|Firmicutes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
YHH1_k127_6786317_4	272134.KB731324_gene4747	6.18e-07	51.0	COG1215@1|root,COG1215@2|Bacteria,1FZZM@1117|Cyanobacteria,1H716@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_6786317_2	374847.Kcr_0835	1.447e-32	136.0	COG1478@1|root,arCOG02714@2157|Archaea	2157|Archaea	E	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives	cofE	GO:0003674,GO:0003824,GO:0016874,GO:0016879,GO:0016881,GO:0052618	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
YHH1_k127_6786317_1	1433126.BN938_2948	1.219e-128	421.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,2FMSR@200643|Bacteroidia,22VRM@171550|Rikenellaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
YHH1_k127_6786317_0	1501230.ET33_15455	1.393e-148	481.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,26RN2@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.2	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YHH1_k127_6786317_3	926550.CLDAP_03620	7.745e-32	132.0	COG0062@1|root,COG0062@2|Bacteria,2G8T6@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX	-	-	5.1.99.6	ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	YjeF_N
YHH1_k127_6810821_1	1034943.BN1094_02167	6.816e-116	381.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1JDPB@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH1_k127_6810821_0	443144.GM21_1334	3.158e-179	577.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
YHH1_k127_6810821_2	796620.VIBC2010_19805	0.0001162	50.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1XT8R@135623|Vibrionales	135623|Vibrionales	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
YHH1_k127_6854490_2	247633.GP2143_13661	5.587e-40	151.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,1RRYS@1236|Gammaproteobacteria,1J6RV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
YHH1_k127_6854490_0	1380390.JIAT01000009_gene710	1.803e-61	223.0	COG3892@1|root,COG3892@2|Bacteria,2INPC@201174|Actinobacteria,4CRB8@84995|Rubrobacteria	84995|Rubrobacteria	G	Uncharacterized protein conserved in bacteria (DUF2090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2090
YHH1_k127_6854490_4	153721.MYP_82	4.314e-05	50.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,47R98@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
YHH1_k127_6854490_1	1191523.MROS_1700	1.301e-54	202.0	COG0648@1|root,COG0648@2|Bacteria	2|Bacteria	L	deoxyribonuclease IV (phage-T4-induced) activity	nfo	GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
YHH1_k127_6854490_3	743525.TSC_c05820	1.36e-12	70.0	COG0232@1|root,COG0232@2|Bacteria,1WI39@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the dGTPase family. Type 2 subfamily	-	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
YHH1_k127_6882963_0	926569.ANT_06210	1.52e-33	148.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi	200795|Chloroflexi	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
YHH1_k127_6882963_3	399550.Smar_1328	5.928e-20	96.0	COG0500@1|root,arCOG01631@2157|Archaea,2XR0B@28889|Crenarchaeota	28889|Crenarchaeota	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	DOT1
YHH1_k127_6882963_4	161156.JQKW01000008_gene447	3.402e-14	84.0	COG0438@1|root,COG0438@2|Bacteria,2GI3U@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Glycosyl transferase 4-like domain	-	-	2.4.1.345,2.4.1.348	ko:K08256,ko:K12995	-	-	R11702	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_6882963_1	1121938.AUDY01000011_gene569	2.067e-28	128.0	COG0438@1|root,COG0438@2|Bacteria,1VBZX@1239|Firmicutes,4IQDM@91061|Bacilli,3NFTX@45667|Halobacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_6882963_5	158189.SpiBuddy_2098	1.764e-07	57.0	COG2840@1|root,COG2840@2|Bacteria,2J57A@203691|Spirochaetes	203691|Spirochaetes	S	Smr domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Smr
YHH1_k127_6882963_2	216591.BCAS0551	1.963e-26	110.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,1K8CW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH1_k127_6899842_4	309801.trd_0959	1.434e-35	139.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi,27YAA@189775|Thermomicrobia	189775|Thermomicrobia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YHH1_k127_6899842_3	999415.HMPREF9943_00577	1.318e-38	147.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,3VQQU@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YHH1_k127_6899842_8	469381.Dpep_1960	1.261e-11	65.0	COG0257@1|root,COG0257@2|Bacteria,3TBU3@508458|Synergistetes	508458|Synergistetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
YHH1_k127_6899842_7	1541959.KQ51_00207	4.68e-22	97.0	COG0361@1|root,COG0361@2|Bacteria,3WTVD@544448|Tenericutes	544448|Tenericutes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
YHH1_k127_6899842_1	1144275.COCOR_03065	1.141e-80	276.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria,2YU2D@29|Myxococcales	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH1_k127_6899842_6	1123372.AUIT01000013_gene1722	2.58e-31	131.0	COG0563@1|root,COG0563@2|Bacteria,2GGXU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
YHH1_k127_6899842_0	273068.TTE2272	7.549e-100	340.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,42ESN@68295|Thermoanaerobacterales	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YHH1_k127_6899842_5	760142.Hipma_1358	3.223e-32	131.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2WQQ4@28221|Deltaproteobacteria,2M76B@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
YHH1_k127_6899842_2	665571.STHERM_c06320	1.345e-39	153.0	COG0693@1|root,COG0693@2|Bacteria,2JB8Z@203691|Spirochaetes	203691|Spirochaetes	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
YHH1_k127_6957652_2	383372.Rcas_4314	5.918e-09	61.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,3755Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_6957652_1	858215.Thexy_1896	6.89e-28	121.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,42FNR@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM Phosphoribosyltransferase	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
YHH1_k127_6957652_0	273068.TTE0523	5.82e-96	325.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,42EU5@68295|Thermoanaerobacterales	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH1_k127_6957652_3	926550.CLDAP_28940	4.825e-08	66.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	YSIRK_signal
YHH1_k127_703749_2	264732.Moth_1705	7.423e-06	55.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24BAQ@186801|Clostridia,42J11@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidoglycan-binding LysM	safA	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
YHH1_k127_703749_0	485916.Dtox_1961	1.405e-18	93.0	COG3210@1|root,COG3656@1|root,COG5492@1|root,COG3210@2|Bacteria,COG3656@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,267DX@186807|Peptococcaceae	186801|Clostridia	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
YHH1_k127_703749_1	1121920.AUAU01000019_gene2599	1.3e-12	70.0	COG2119@1|root,COG2119@2|Bacteria	2|Bacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
YHH1_k127_7040150_3	1137281.D778_00297	1.604e-18	92.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,1I4IA@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_7040150_0	484770.UFO1_1386	3.213e-142	472.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,4H23R@909932|Negativicutes	909932|Negativicutes	C	hydrogenase, Fe-only	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,NADH-G_4Fe-4S_3
YHH1_k127_7040150_1	572544.Ilyop_1220	2.149e-61	224.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,378S3@32066|Fusobacteria	2|Bacteria	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	hoxF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
YHH1_k127_7040150_2	243164.DET0148	5.9e-23	105.0	2DRGB@1|root,308ZI@2|Bacteria,2GAPN@200795|Chloroflexi,34CZP@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7101404_1	261292.Nit79A3_3155	0.0009593	44.0	COG1216@1|root,COG1216@2|Bacteria,1N5DV@1224|Proteobacteria,2WB4B@28216|Betaproteobacteria,372A6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH1_k127_7101404_0	370438.PTH_0613	2.177e-163	533.0	COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,247VC@186801|Clostridia,25ZZT@186807|Peptococcaceae	186801|Clostridia	L	Secreted protein with C-terminal beta-propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel,Cu_amine_oxidN1
YHH1_k127_7157488_1	880073.Calab_0477	1.273e-44	167.0	COG0566@1|root,COG0566@2|Bacteria,2NQ0F@2323|unclassified Bacteria	2|Bacteria	J	tRNA rRNA methyltransferase	spoU	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase
YHH1_k127_7157488_0	926561.KB900617_gene2076	2.086e-110	370.0	COG0438@1|root,COG0438@2|Bacteria,1TQN3@1239|Firmicutes,24ARN@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_7157488_2	638303.Thal_1400	4.829e-32	128.0	COG0313@1|root,COG0313@2|Bacteria,2G3XU@200783|Aquificae	200783|Aquificae	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YHH1_k127_7164474_2	367299.JOEE01000001_gene1998	0.0003293	49.0	COG1082@1|root,COG1082@2|Bacteria,2GJ6E@201174|Actinobacteria,4FEA7@85021|Intrasporangiaceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH1_k127_7164474_1	575609.HMPREF0629_00096	1.503e-27	123.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia	186801|Clostridia	L	'dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
YHH1_k127_7164474_0	243231.GSU1651	3.793e-80	276.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,42NRA@68525|delta/epsilon subdivisions,2WJ62@28221|Deltaproteobacteria,43TID@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
YHH1_k127_7221852_6	1121104.AQXH01000001_gene2104	7.9e-20	97.0	COG0281@1|root,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,PTA_PTB,malic
YHH1_k127_7221852_0	522772.Dacet_2325	5.479e-154	496.0	COG0112@1|root,COG0112@2|Bacteria,2GERI@200930|Deferribacteres	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
YHH1_k127_7221852_1	941824.TCEL_01635	6.79e-114	378.0	COG0438@1|root,COG0438@2|Bacteria,1TQN3@1239|Firmicutes,24ARN@186801|Clostridia,36EHG@31979|Clostridiaceae	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_7221852_2	877411.JMMA01000002_gene216	2.73e-44	168.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3WHRC@541000|Ruminococcaceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
YHH1_k127_7221852_3	1120746.CCNL01000014_gene2050	9.751e-40	155.0	COG0652@1|root,COG0652@2|Bacteria,2NPIT@2323|unclassified Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
YHH1_k127_7221852_5	395495.Lcho_1748	5.569e-32	128.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,1KKVN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
YHH1_k127_7221852_7	324057.Pjdr2_1289	3.134e-05	48.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,26Z3P@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
YHH1_k127_7221852_4	742743.HMPREF9453_00447	8.356e-37	145.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4H3YT@909932|Negativicutes	909932|Negativicutes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
YHH1_k127_7290947_0	237368.SCABRO_03785	1.661e-57	207.0	COG3385@1|root,COG3385@2|Bacteria,2IZDT@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS4 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH1_k127_7290947_1	1441930.Z042_04920	9.597e-27	110.0	COG2801@1|root,COG2801@2|Bacteria,1MWNX@1224|Proteobacteria,1RW9F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_28,HTH_32,rve,rve_3
YHH1_k127_7298991_2	861299.J421_3189	5.872e-07	55.0	COG0858@1|root,COG0858@2|Bacteria,1ZTWI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
YHH1_k127_7298991_0	1121129.KB903360_gene3400	0.0	1314.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia,22W4Y@171551|Porphyromonadaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase (glutamine-hydrolyzing)	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YHH1_k127_7298991_1	509191.AEDB02000019_gene4451	2.144e-10	72.0	COG2755@1|root,COG3209@1|root,COG5263@1|root,COG2755@2|Bacteria,COG3209@2|Bacteria,COG5263@2|Bacteria,1TQTD@1239|Firmicutes,25FAD@186801|Clostridia,3WNFD@541000|Ruminococcaceae	186801|Clostridia	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,SLH
YHH1_k127_7312825_4	1380355.JNIJ01000014_gene569	1.576e-11	66.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,3JUZI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
YHH1_k127_7312825_3	1201292.DR75_1270	4.439e-17	86.0	COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli,4B2H4@81852|Enterococcaceae	91061|Bacilli	C	Flavodoxin	ykuP	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
YHH1_k127_7312825_1	403833.Pmob_1066	1.534e-92	320.0	COG0166@1|root,COG0166@2|Bacteria,2GC7K@200918|Thermotogae	200918|Thermotogae	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iLJ478.TM1385	PGI
YHH1_k127_7312825_2	1408473.JHXO01000005_gene1669	3.89e-55	197.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,2FT1X@200643|Bacteroidia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
YHH1_k127_7312825_0	381764.Fnod_1680	2.343e-148	491.0	COG0021@1|root,COG0021@2|Bacteria,2GC9S@200918|Thermotogae	200918|Thermotogae	G	Belongs to the transketolase family	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
YHH1_k127_7573728_0	1382306.JNIM01000001_gene3556	0.0	1294.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH1_k127_7573728_1	311424.DhcVS_544	1.562e-238	757.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,34CZR@301297|Dehalococcoidia	301297|Dehalococcoidia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH1_k127_7579742_1	1500281.JQKZ01000015_gene2145	4.649e-05	48.0	2AAAU@1|root,30ZKF@2|Bacteria,4PDWW@976|Bacteroidetes,1IEA8@117743|Flavobacteriia,3ZT19@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7579742_0	1131266.ARWQ01000004_gene1465	3.261e-07	59.0	COG0316@1|root,arCOG04560@2157|Archaea,41SKH@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Iron-sulfur cluster assembly accessory protein	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
YHH1_k127_7596781_1	743525.TSC_c00640	0.0002231	46.0	COG1694@1|root,COG3956@2|Bacteria,1WK1U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM MazG family protein	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
YHH1_k127_7596781_0	1121430.JMLG01000001_gene2105	4.529e-151	493.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25ZZN@186807|Peptococcaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
YHH1_k127_7687189_0	1121935.AQXX01000120_gene4916	8.756e-35	144.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,1MVN2@1224|Proteobacteria,1RS1C@1236|Gammaproteobacteria,1XIZ5@135619|Oceanospirillales	135619|Oceanospirillales	HJ	GNAT family acetyltransferase	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Mur_ligase_C,Mur_ligase_M,RimK
YHH1_k127_7687189_1	1232666.JANE01000062_gene2330	3.698e-26	117.0	28H95@1|root,2Z7KY@2|Bacteria,1TQTR@1239|Firmicutes,4HB82@91061|Bacilli,4GYWM@90964|Staphylococcaceae	91061|Bacilli	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
YHH1_k127_7736183_0	1158318.ATXC01000001_gene210	1.093e-64	224.0	COG2406@1|root,COG2406@2|Bacteria,2G4BP@200783|Aquificae	200783|Aquificae	S	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
YHH1_k127_7736183_1	96561.Dole_1873	1.153e-48	184.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YHH1_k127_7739214_0	671143.DAMO_2856	4.745e-185	593.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
YHH1_k127_7744436_0	1313301.AUGC01000016_gene837	2.886e-148	478.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH1_k127_7744436_2	1268635.Loa_01104	1.942e-13	72.0	2ENCP@1|root,33G06@2|Bacteria,1P756@1224|Proteobacteria,1SU1K@1236|Gammaproteobacteria,1JF0F@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7744436_1	747365.Thena_0155	4.809e-52	209.0	COG0342@1|root,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,42F9I@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YHH1_k127_7747050_4	1121028.ARQE01000001_gene3587	6.381e-05	46.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,2PJXS@255475|Aurantimonadaceae	28211|Alphaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
YHH1_k127_7747050_1	1382306.JNIM01000001_gene41	1.035e-104	353.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
YHH1_k127_7747050_0	1449126.JQKL01000021_gene83	3.935e-128	420.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,267RF@186813|unclassified Clostridiales	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YHH1_k127_7747050_3	868595.Desca_1336	3.032e-31	142.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,25C6H@186801|Clostridia,2601V@186807|Peptococcaceae	186801|Clostridia	L	helicase involved in DNA repair and perhaps also replication	dinG	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T,RadC,ResIII
YHH1_k127_7747050_2	1382356.JQMP01000004_gene473	3.1e-72	269.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi,27Y3G@189775|Thermomicrobia	189775|Thermomicrobia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
YHH1_k127_7838466_3	1382356.JQMP01000003_gene2087	0.0003627	47.0	COG0143@1|root,COG0143@2|Bacteria,2G6VG@200795|Chloroflexi,27Y98@189775|Thermomicrobia	189775|Thermomicrobia	J	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
YHH1_k127_7838466_0	880073.Calab_0988	2.861e-82	291.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2NPAA@2323|unclassified Bacteria	2|Bacteria	S	AMMECR1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
YHH1_k127_7838466_1	1459636.NTE_00759	4.975e-23	105.0	COG1027@1|root,COG1670@1|root,arCOG00842@2157|Archaea,arCOG01750@2157|Archaea,41S9C@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
YHH1_k127_7838466_2	5860.XP_008626227.1	9.28e-10	68.0	2D07M@1|root,2SD3W@2759|Eukaryota,3YB5Q@5794|Apicomplexa,3KAQH@422676|Aconoidasida,3YWY3@5819|Haemosporida	422676|Aconoidasida	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
YHH1_k127_787870_2	1333523.L593_08180	2.172e-08	62.0	arCOG07781@1|root,arCOG07781@2157|Archaea,2XZ14@28890|Euryarchaeota,23UTA@183963|Halobacteria	183963|Halobacteria	S	COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD
YHH1_k127_787870_1	525282.HMPREF0391_10333	5.664e-18	97.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,22HB0@1570339|Peptoniphilaceae	186801|Clostridia	D	Peptidase, M23 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
YHH1_k127_787870_0	469383.Cwoe_5824	2.98e-24	108.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GISS@201174|Actinobacteria,4CPN9@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH1_k127_7908487_1	933262.AXAM01000005_gene2489	2.214e-96	321.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42MR2@68525|delta/epsilon subdivisions,2WKKH@28221|Deltaproteobacteria,2MJG1@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg
YHH1_k127_7908487_0	933262.AXAM01000005_gene2490	2.379e-169	540.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2MHZP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
YHH1_k127_7963179_1	1122169.AREN01000042_gene926	4.557e-15	86.0	2BHYF@1|root,32C2Q@2|Bacteria,1QJBB@1224|Proteobacteria,1THA1@1236|Gammaproteobacteria,1JDH9@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_7963179_0	1232410.KI421413_gene750	1.097e-25	124.0	COG2885@1|root,COG3210@1|root,COG5184@1|root,COG5276@1|root,COG2885@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
YHH1_k127_7975473_1	485913.Krac_12345	2.805e-34	144.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
YHH1_k127_7975473_0	768670.Calni_1798	6.487e-48	187.0	COG0399@1|root,COG0399@2|Bacteria,2GF7R@200930|Deferribacteres	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH1_k127_8012471_1	1031288.AXAA01000011_gene640	1.28e-35	144.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,36DGZ@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
YHH1_k127_8012471_0	1236542.BALM01000001_gene304	6.78e-49	184.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,2Q8WF@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
YHH1_k127_8012471_2	1121342.AUCO01000005_gene152	4.555e-07	58.0	COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,36UK6@31979|Clostridiaceae	186801|Clostridia	GJM	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	2.7.7.13,2.7.7.71	ko:K00966,ko:K15669	ko00051,ko00520,ko00540,ko01100,ko01110,map00051,map00520,map00540,map01100,map01110	M00114,M00361,M00362	R00885,R09772	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hydrolase_like,NTP_transferase
YHH1_k127_8045637_0	349161.Dred_2499	1.244e-26	119.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,260NG@186807|Peptococcaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
YHH1_k127_8045637_1	521098.Aaci_1997	2.059e-20	98.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,278G9@186823|Alicyclobacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YHH1_k127_8045637_2	1385513.N780_16775	0.0004688	51.0	COG1226@1|root,32XJ0@2|Bacteria,1VDRQ@1239|Firmicutes,4HKXM@91061|Bacilli,2YAIS@289201|Pontibacillus	91061|Bacilli	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
YHH1_k127_8102630_0	1244528.CFT03427_1190	5.266e-05	54.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2YM7Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Fibronectin type 3 domain-containing protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
YHH1_k127_8112702_2	1347368.HG964405_gene5938	7.86e-08	59.0	COG1959@1|root,COG1959@2|Bacteria,1V6FG@1239|Firmicutes,4HMA4@91061|Bacilli,1ZF97@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH1_k127_8112702_1	1487953.JMKF01000065_gene4698	3.268e-77	267.0	COG0396@1|root,COG0396@2|Bacteria,1G11H@1117|Cyanobacteria,1H7BY@1150|Oscillatoriales	1117|Cyanobacteria	O	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
YHH1_k127_8112702_0	1321778.HMPREF1982_00935	2.624e-175	561.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,26ACQ@186813|unclassified Clostridiales	186801|Clostridia	O	Uncharacterized protein family (UPF0051)	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
YHH1_k127_8143762_0	156889.Mmc1_3327	3.784e-108	357.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH1_k127_8143762_1	1123226.KB899277_gene1582	3.414e-107	356.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,26RWY@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YHH1_k127_8143762_2	446466.Cfla_1478	2.111e-24	108.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4F2QP@85016|Cellulomonadaceae	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
YHH1_k127_8143762_3	653045.Strvi_5898	3.904e-11	65.0	COG1686@1|root,COG1686@2|Bacteria,2GJ7C@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
YHH1_k127_8283413_4	36080.S2J835	2.606e-16	86.0	COG0125@1|root,KOG3327@2759|Eukaryota,39U2H@33154|Opisthokonta,3P2YY@4751|Fungi,1GUVZ@112252|Fungi incertae sedis	4751|Fungi	F	Thymidylate kinase	CDC8	GO:0003674,GO:0003824,GO:0004550,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006165,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
YHH1_k127_8283413_1	868864.Dester_0631	1.057e-120	417.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G3KI@200783|Aquificae	200783|Aquificae	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
YHH1_k127_8283413_0	311424.DhcVS_1051	1.358e-182	593.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,34D01@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YHH1_k127_8283413_3	342949.PNA2_1518	8.05e-29	129.0	COG1041@1|root,arCOG00047@2157|Archaea,2Y2EJ@28890|Euryarchaeota,2432J@183968|Thermococci	183968|Thermococci	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
YHH1_k127_8283413_2	195522.BD01_1491	1.186e-42	163.0	COG0438@1|root,arCOG01411@2157|Archaea,2Y8B0@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_8340188_1	479434.Sthe_0915	4.691e-90	307.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi,27XRB@189775|Thermomicrobia	189775|Thermomicrobia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YHH1_k127_8340188_0	857293.CAAU_0461	1.499e-179	580.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,36E1A@31979|Clostridiaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
YHH1_k127_8340261_7	1167632.AJTR01000026_gene1699	4.284e-06	53.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,4GXGA@90964|Staphylococcaceae	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
YHH1_k127_8340261_3	1123277.KB893181_gene2211	5.626e-21	105.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,47MT6@768503|Cytophagia	976|Bacteroidetes	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH1_k127_8340261_4	1123518.ARWI01000001_gene1919	9.442e-12	73.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,462CA@72273|Thiotrichales	72273|Thiotrichales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH1_k127_8340261_0	523850.TON_1640	2.715e-65	230.0	COG0149@1|root,arCOG01087@2157|Archaea,2XTY3@28890|Euryarchaeota,24332@183968|Thermococci	183968|Thermococci	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM,ThiG
YHH1_k127_8340261_5	469610.HMPREF0189_00814	4.805e-08	66.0	COG3307@1|root,COG3307@2|Bacteria,1NGAP@1224|Proteobacteria,2VXZ1@28216|Betaproteobacteria	28216|Betaproteobacteria	M	O-Antigen Polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH1_k127_8340261_8	1492738.FEM21_01140	2.195e-05	57.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1HXQ5@117743|Flavobacteriia,2NU91@237|Flavobacterium	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
YHH1_k127_8340261_1	43989.cce_2666	1.468e-59	221.0	COG2211@1|root,COG2211@2|Bacteria,1G0YG@1117|Cyanobacteria,3KFV5@43988|Cyanothece	1117|Cyanobacteria	G	biopterin transport-related protein BT1	-	GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0008517,GO:0015075,GO:0015231,GO:0015238,GO:0015318,GO:0015350,GO:0015711,GO:0015849,GO:0015884,GO:0015885,GO:0015893,GO:0022857,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0051958,GO:0055085,GO:0071702,GO:0071705,GO:0072337,GO:0072349,GO:0090482,GO:0098656,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	BT1
YHH1_k127_8340261_2	504728.K649_08515	4.626e-23	106.0	COG0317@1|root,COG0317@2|Bacteria,1WID2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
YHH1_k127_8340261_6	1123274.KB899411_gene3072	9.524e-07	59.0	COG1378@1|root,COG1378@2|Bacteria	2|Bacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YHH1_k127_8352483_1	1158760.AQXP01000053_gene1392	4.079e-61	226.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1X01T@135613|Chromatiales	135613|Chromatiales	HJ	TIGRFAM alpha-L-glutamate ligase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
YHH1_k127_8352483_3	331678.Cphamn1_2200	1.518e-35	142.0	COG0629@1|root,COG0629@2|Bacteria,1FE0M@1090|Chlorobi	1090|Chlorobi	L	PFAM single-strand binding protein Primosomal replication protein n	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YHH1_k127_8352483_2	635013.TherJR_2420	1.614e-46	183.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia	186801|Clostridia	D	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
YHH1_k127_8352483_4	246194.CHY_0195	9.302e-27	118.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,42G72@68295|Thermoanaerobacterales	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
YHH1_k127_8352483_6	596319.STAWA0001_0748	4.009e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,4GX8R@90964|Staphylococcaceae	91061|Bacilli	S	Tetratricopeptide repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
YHH1_k127_8352483_0	562970.Btus_0496	1.366e-144	470.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,278X3@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YHH1_k127_8352483_5	335543.Sfum_2997	2.304e-13	77.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2WRH7@28221|Deltaproteobacteria,2MQN6@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
YHH1_k127_8488148_0	596323.HMPREF0554_0585	4.673e-76	261.0	COG0528@1|root,COG0528@2|Bacteria,3786C@32066|Fusobacteria	32066|Fusobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YHH1_k127_8488148_1	886379.AEWI01000012_gene1053	3.653e-39	150.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,2FPZE@200643|Bacteroidia,3XJMJ@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosome recycling factor	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
YHH1_k127_8511524_0	1461580.CCAS010000026_gene2583	4.818e-101	340.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,1ZBJB@1386|Bacillus	91061|Bacilli	L	Belongs to the methyltransferase superfamily	ypsC	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
YHH1_k127_8511524_5	448385.sce6441	3.871e-05	56.0	2AIXD@1|root,319F1@2|Bacteria,1Q2IM@1224|Proteobacteria,4385A@68525|delta/epsilon subdivisions,2X3FB@28221|Deltaproteobacteria,2YVU7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8511524_6	1192034.CAP_2719	0.0001554	54.0	2AIXD@1|root,319F1@2|Bacteria,1Q2IM@1224|Proteobacteria,4385A@68525|delta/epsilon subdivisions,2X3FB@28221|Deltaproteobacteria,2YVU7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8511524_4	579137.Metvu_1715	6.919e-06	55.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0G0@28890|Euryarchaeota,23QXI@183939|Methanococci	183939|Methanococci	K	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
YHH1_k127_8511524_2	1121859.KB890738_gene3412	8.185e-13	77.0	COG0739@1|root,COG0739@2|Bacteria,4NN4Q@976|Bacteroidetes,47PNX@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH1_k127_8511524_1	177437.HRM2_10500	6.095e-18	94.0	COG5653@1|root,COG5653@2|Bacteria,1MV00@1224|Proteobacteria,42PW5@68525|delta/epsilon subdivisions,2WKPE@28221|Deltaproteobacteria,2MIEF@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
YHH1_k127_8511524_3	679926.Mpet_0549	6.455e-12	67.0	COG3476@1|root,arCOG04434@2157|Archaea,2XYQD@28890|Euryarchaeota,2NAZX@224756|Methanomicrobia	224756|Methanomicrobia	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
YHH1_k127_852505_1	314275.MADE_1007530	5.531e-53	197.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
YHH1_k127_852505_0	195522.BD01_1492	4.792e-59	217.0	COG0438@1|root,arCOG01410@2157|Archaea,2Y2DM@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_852505_2	1304885.AUEY01000030_gene2445	3.172e-50	189.0	COG0438@1|root,COG0438@2|Bacteria,1N1RZ@1224|Proteobacteria,42UHY@68525|delta/epsilon subdivisions,2WQD7@28221|Deltaproteobacteria,2MKYI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_8570003_3	926550.CLDAP_29090	2.268e-20	109.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
YHH1_k127_8570003_0	1313421.JHBV01000038_gene2837	4.454e-79	276.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH1_k127_8570003_1	909663.KI867150_gene1723	1.273e-65	233.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,2MRJ5@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
YHH1_k127_8570003_2	519441.Smon_0984	5.919e-40	153.0	COG0817@1|root,COG0817@2|Bacteria,37A4F@32066|Fusobacteria	32066|Fusobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
YHH1_k127_8579307_1	1449345.JHWC01000008_gene1709	1.415e-19	91.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2YNWA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0321	Guanylate_kin
YHH1_k127_8579307_0	266117.Rxyl_0676	1.28e-210	677.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CU4U@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM UvrB UvrC protein AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YHH1_k127_8592340_0	1033810.HLPCO_000126	1.665e-61	219.0	COG0743@1|root,COG0743@2|Bacteria,2NNW2@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188	DXPR_C,DXP_redisom_C,DXP_reductoisom
YHH1_k127_8592340_1	888727.HMPREF9092_0343	4.01e-46	181.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,3WCJD@538999|Clostridiales incertae sedis	186801|Clostridia	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
YHH1_k127_8592340_2	1354300.AUQY01000005_gene138	4.272e-14	76.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,22FZ4@1570339|Peptoniphilaceae	186801|Clostridia	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YHH1_k127_8613028_0	1121428.DESHY_80091___1	6.963e-178	575.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
YHH1_k127_8616684_2	360104.CCC13826_2017	2.149e-17	89.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,42RGH@68525|delta/epsilon subdivisions,2YP5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
YHH1_k127_8616684_0	585530.HMPREF0183_0154	6.788e-80	285.0	COG1215@1|root,COG1215@2|Bacteria,2IK1V@201174|Actinobacteria,4F9BY@85019|Brevibacteriaceae	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8616684_1	909663.KI867150_gene413	2.675e-37	145.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2MQ81@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YHH1_k127_8678814_0	941824.TCEL_01878	1.615e-141	470.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,36DDP@31979|Clostridiaceae	186801|Clostridia	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YHH1_k127_8679137_10	197221.22295631	4.367e-11	72.0	COG0719@1|root,COG0719@2|Bacteria,1G0K0@1117|Cyanobacteria	1117|Cyanobacteria	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufD	-	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
YHH1_k127_8679137_0	203120.LEUM_2036	1.087e-119	396.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,4AWWC@81850|Leuconostocaceae	91061|Bacilli	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YHH1_k127_8679137_6	525904.Tter_1695	2.447e-35	139.0	COG0822@1|root,COG0822@2|Bacteria,2NPXN@2323|unclassified Bacteria	2|Bacteria	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YHH1_k127_8679137_8	436114.SYO3AOP1_0975	1.416e-19	91.0	COG0759@1|root,COG0759@2|Bacteria,2G48K@200783|Aquificae	200783|Aquificae	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
YHH1_k127_8679137_2	272624.lpg1676	9.103e-85	296.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,1SVID@1236|Gammaproteobacteria,1JD85@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
YHH1_k127_8679137_7	1157490.EL26_12425	1.424e-34	140.0	COG0681@1|root,COG0681@2|Bacteria,1TRAV@1239|Firmicutes,4HCTU@91061|Bacilli,27APW@186823|Alicyclobacillaceae	91061|Bacilli	U	Belongs to the peptidase S26 family	sipS3	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YHH1_k127_8679137_5	696281.Desru_0862	1.814e-46	175.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,2626V@186807|Peptococcaceae	186801|Clostridia	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
YHH1_k127_8679137_4	289377.HL41_01980	2.978e-69	247.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GHB5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
YHH1_k127_8679137_1	1288963.ADIS_1567	3.291e-104	347.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47K1Z@768503|Cytophagia	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
YHH1_k127_8679137_3	1122176.KB903532_gene2508	1.554e-82	285.0	COG0701@1|root,COG0701@2|Bacteria,4NDUJ@976|Bacteroidetes,1IWYA@117747|Sphingobacteriia	976|Bacteroidetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
YHH1_k127_8679137_9	324057.Pjdr2_0528	9.62e-18	90.0	COG0154@1|root,COG0726@1|root,COG0154@2|Bacteria,COG0726@2|Bacteria,1TRFI@1239|Firmicutes,4IPR7@91061|Bacilli,26QQV@186822|Paenibacillaceae	91061|Bacilli	GJ	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase,SLH
YHH1_k127_870540_2	439235.Dalk_2965	7.698e-51	182.0	COG2043@1|root,COG2043@2|Bacteria,1R8EH@1224|Proteobacteria,42Q2F@68525|delta/epsilon subdivisions,2WJZN@28221|Deltaproteobacteria,2MHN8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
YHH1_k127_870540_0	1121405.dsmv_2230	2.648e-169	545.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria,2MI43@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
YHH1_k127_870540_1	933262.AXAM01000036_gene2170	2.446e-75	258.0	COG0613@1|root,COG0613@2|Bacteria,1Q7I9@1224|Proteobacteria,42M1D@68525|delta/epsilon subdivisions,2WIMC@28221|Deltaproteobacteria,2MIFA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8748918_0	797114.C475_04146	3.558e-25	108.0	COG0346@1|root,arCOG02708@2157|Archaea,2Y4DN@28890|Euryarchaeota,2404T@183963|Halobacteria	183963|Halobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_8748918_1	34506.g6239	0.0002152	45.0	COG0654@1|root,KOG3855@2759|Eukaryota,38FN2@33154|Opisthokonta,3BAK6@33208|Metazoa,3CYXR@33213|Bilateria,40CPH@6231|Nematoda,1KVIW@119089|Chromadorea,40V9S@6236|Rhabditida	33208|Metazoa	CH	FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3- polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin ferredoxin reductase system to COQ6	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
YHH1_k127_8827526_1	555088.DealDRAFT_1683	3.139e-44	166.0	COG0636@1|root,COG0636@2|Bacteria,1V786@1239|Firmicutes,24HBF@186801|Clostridia	186801|Clostridia	C	Belongs to the V-ATPase proteolipid subunit family	ntpK	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
YHH1_k127_8827526_0	697281.Mahau_0625	2.15e-88	316.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,42EMM@68295|Thermoanaerobacterales	186801|Clostridia	C	116 kDa subunit	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
YHH1_k127_8827526_2	1122173.AXVL01000014_gene98	7.935e-12	78.0	COG0791@1|root,COG0791@2|Bacteria,37A9V@32066|Fusobacteria	32066|Fusobacteria	M	NlpC P60 family protein	-	-	3.4.17.13	ko:K13694	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
YHH1_k127_8940107_3	1444711.CCJF01000005_gene357	5.32e-22	101.0	2C3WA@1|root,2Z8P1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
YHH1_k127_8940107_2	382245.ASA_1635	1.67e-49	179.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria,1Y4GF@135624|Aeromonadales	135624|Aeromonadales	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
YHH1_k127_8940107_1	331678.Cphamn1_1369	2.434e-65	228.0	COG0288@1|root,COG0288@2|Bacteria,1FERE@1090|Chlorobi	1090|Chlorobi	H	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
YHH1_k127_8940107_0	179408.Osc7112_1615	1.574e-102	337.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
YHH1_k127_8959129_0	479434.Sthe_2302	1.953e-39	164.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
YHH1_k127_8959129_1	1267535.KB906767_gene5183	3.484e-20	95.0	COG0802@1|root,COG0802@2|Bacteria,3Y4WF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised protein family UPF0079, ATPase	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
YHH1_k127_8959129_2	1307436.PBF_08293	2.159e-10	74.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4HB9Q@91061|Bacilli,1ZBKA@1386|Bacillus	91061|Bacilli	D	peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
YHH1_k127_8959129_3	857290.HMPREF9156_01160	4.77e-07	56.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_29,HTH_32,HTH_33
YHH1_k127_8999396_0	456442.Mboo_1652	3.83e-48	182.0	COG2208@1|root,arCOG02362@1|root,arCOG02362@2157|Archaea,arCOG06893@2157|Archaea	2157|Archaea	KT	stage II sporulation	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
YHH1_k127_8999396_1	1191523.MROS_0810	5.664e-15	80.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	23S_rRNA_IVP
YHH1_k127_9123552_3	316274.Haur_0358	2.267e-39	149.0	COG0277@1|root,COG0277@2|Bacteria,2G8D5@200795|Chloroflexi	200795|Chloroflexi	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YHH1_k127_9123552_0	96561.Dole_2616	1.295e-174	561.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJ25@28221|Deltaproteobacteria,2MPYQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
YHH1_k127_9123552_1	706587.Desti_2415	1.741e-124	408.0	COG0655@1|root,COG3255@1|root,COG0655@2|Bacteria,COG3255@2|Bacteria,1MYKZ@1224|Proteobacteria,42SN9@68525|delta/epsilon subdivisions,2WP58@28221|Deltaproteobacteria,2MRMQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,SCP2
YHH1_k127_9123552_2	909663.KI867150_gene2332	6.688e-47	171.0	COG2337@1|root,COG2337@2|Bacteria,1N0JV@1224|Proteobacteria,42STH@68525|delta/epsilon subdivisions,2WP6X@28221|Deltaproteobacteria,2MSFP@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH1_k127_915690_1	926692.AZYG01000051_gene1872	2.784e-21	100.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia	186801|Clostridia	J	Acetyltransferase GNAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YHH1_k127_915690_0	1160707.AJIK01000001_gene402	4.156e-122	403.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,26CUB@186818|Planococcaceae	91061|Bacilli	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH1_k127_9166399_0	357808.RoseRS_3578	3.089e-80	285.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,374ZJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
YHH1_k127_9166399_1	236814.IX39_06900	1.002e-27	115.0	COG0797@1|root,COG0797@2|Bacteria,4NSF1@976|Bacteroidetes,1I2ZJ@117743|Flavobacteriia,3ZS3B@59732|Chryseobacterium	976|Bacteroidetes	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
YHH1_k127_919673_7	478749.BRYFOR_05053	7.37e-05	55.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
YHH1_k127_919673_6	1485545.JQLW01000007_gene641	6.729e-05	48.0	2E4KV@1|root,32ZFU@2|Bacteria,1NPD5@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
YHH1_k127_919673_5	742727.HMPREF9447_05094	3.72e-07	60.0	COG3187@1|root,COG3187@2|Bacteria,4NWRF@976|Bacteroidetes,2FNPG@200643|Bacteroidia,4AR39@815|Bacteroidaceae	976|Bacteroidetes	O	Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_919673_3	323097.Nham_2895	1.743e-11	69.0	2ENBK@1|root,33FZ7@2|Bacteria,1N3KU@1224|Proteobacteria,2UE58@28211|Alphaproteobacteria,3K5UU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_919673_1	1298593.TOL_2886	4.454e-26	109.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1XKKY@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YHH1_k127_919673_2	1217656.F964_02326	6.814e-16	85.0	COG4122@1|root,COG4122@2|Bacteria,1RKF0@1224|Proteobacteria,1S766@1236|Gammaproteobacteria,3NKU9@468|Moraxellaceae	1236|Gammaproteobacteria	S	O-methyltransferase	mdmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
YHH1_k127_919673_0	1192034.CAP_8119	2.142e-54	209.0	COG5184@1|root,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2YV9Z@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
YHH1_k127_9197840_2	632292.Calhy_1054	1.42e-50	187.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,42F13@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
YHH1_k127_9197840_0	525904.Tter_0502	1.148e-166	542.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YHH1_k127_9197840_1	82654.Pse7367_2319	2.717e-106	383.0	COG0744@1|root,COG0744@2|Bacteria,1G1XF@1117|Cyanobacteria,1H8WS@1150|Oscillatoriales	1117|Cyanobacteria	M	Penicillin-binding protein, 1A family	mrcB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
YHH1_k127_9319931_0	330214.NIDE3501	4.216e-85	303.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
YHH1_k127_9480752_0	926550.CLDAP_20050	1.406e-51	190.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi	200795|Chloroflexi	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YHH1_k127_9508501_2	1121382.JQKG01000005_gene3255	9.514e-23	101.0	COG1162@1|root,COG1162@2|Bacteria	2|Bacteria	S	GTPase activity	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RNHCP,RsgA_GTPase
YHH1_k127_9508501_0	655811.HMPREF0078_0341	1.824e-48	185.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,22G6X@1570339|Peptoniphilaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
YHH1_k127_9508501_1	1111134.HMPREF1253_0890	6.227e-41	160.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,22GPQ@1570339|Peptoniphilaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
YHH1_k127_9522232_4	391625.PPSIR1_18267	6.616e-12	78.0	2DSD6@1|root,33FM0@2|Bacteria,1PBXM@1224|Proteobacteria,43862@68525|delta/epsilon subdivisions,2X3FW@28221|Deltaproteobacteria,2YVX7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9522232_3	1121904.ARBP01000008_gene3265	2.015e-31	141.0	COG4886@1|root,COG4932@1|root,COG5184@1|root,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,4NNEI@976|Bacteroidetes	976|Bacteroidetes	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF1566
YHH1_k127_9522232_0	297246.lpp1645	8.978e-145	471.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1JD00@118969|Legionellales	118969|Legionellales	F	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YHH1_k127_9522232_2	404589.Anae109_2037	6.113e-33	136.0	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2WZ2N@28221|Deltaproteobacteria,2Z16Z@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH1_k127_9522232_1	857293.CAAU_1634	3.912e-111	362.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,36DC4@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
YHH1_k127_9531608_1	1280694.AUJQ01000004_gene698	4.363e-83	288.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3NGF8@46205|Pseudobutyrivibrio	186801|Clostridia	M	Glycosyltransferase family 28 N-terminal domain	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
YHH1_k127_9531608_5	945713.IALB_2354	2.404e-31	131.0	COG0127@1|root,COG0127@2|Bacteria	2|Bacteria	F	nucleoside triphosphate catabolic process	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	-	R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_1875	Ham1p_like
YHH1_k127_9531608_0	1158150.KB906243_gene1663	3.574e-154	501.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1WXCW@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
YHH1_k127_9531608_4	596329.HMPREF0631_1797	1.022e-40	171.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,25R43@186804|Peptostreptococcaceae	186801|Clostridia	S	DHHA1 domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH1_k127_9531608_3	1408439.JHXW01000008_gene287	3.832e-60	216.0	COG0036@1|root,COG0036@2|Bacteria,379G5@32066|Fusobacteria	32066|Fusobacteria	G	Ribulose-phosphate 3-epimerase	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YHH1_k127_9531608_2	309801.trd_0060	1.221e-76	273.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
YHH1_k127_9547904_0	1160707.AJIK01000002_gene459	1.326e-187	601.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,26DYZ@186818|Planococcaceae	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
YHH1_k127_9553528_4	1120951.AUBG01000011_gene2296	1.068e-09	65.0	COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,1I3Z8@117743|Flavobacteriia	976|Bacteroidetes	J	chain release factor	arfB	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
YHH1_k127_9553528_1	237368.SCABRO_00428	3.107e-89	312.0	COG0617@1|root,COG0617@2|Bacteria,2IXYM@203682|Planctomycetes	203682|Planctomycetes	H	tRNA nucleotidyltransferase poly(A) polymerase	papS	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
YHH1_k127_9553528_0	589865.DaAHT2_0059	6.012e-119	390.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria,2MJCB@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH1_k127_9553528_3	868864.Dester_0147	4.085e-16	81.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	relE	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
YHH1_k127_9553528_2	1047013.AQSP01000118_gene1252	3.339e-40	155.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH1_k127_9566489_2	1321372.AQQB01000010_gene895	3.791e-78	269.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4HC6N@91061|Bacilli,1WT59@1307|Streptococcus suis	91061|Bacilli	GM	ATPases associated with a variety of cellular activities	rgpD	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
YHH1_k127_9566489_4	368407.Memar_0190	4.183e-47	179.0	COG1682@1|root,arCOG04339@2157|Archaea,2XYS4@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
YHH1_k127_9566489_1	506534.Rhein_1594	9.135e-88	296.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1WW49@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YHH1_k127_9566489_6	1499967.BAYZ01000139_gene142	2.138e-44	175.0	COG1216@1|root,COG1216@2|Bacteria,2NPYM@2323|unclassified Bacteria	2|Bacteria	L	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
YHH1_k127_9566489_7	290317.Cpha266_2639	3.366e-22	100.0	2DNS7@1|root,32YWC@2|Bacteria,1FFKA@1090|Chlorobi	1090|Chlorobi	J	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YHH1_k127_9566489_3	224308.BSU37810	5.762e-56	200.0	COG1898@1|root,COG1898@2|Bacteria,1V4G5@1239|Firmicutes,4HGWJ@91061|Bacilli,1ZFSW@1386|Bacillus	91061|Bacilli	M	Spore Coat	spsL	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
YHH1_k127_9566489_0	634956.Geoth_0303	3.011e-124	408.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,1WHF3@129337|Geobacillus	91061|Bacilli	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YHH1_k127_9566489_5	419665.Maeo_0394	1.996e-46	173.0	COG0438@1|root,arCOG01411@2157|Archaea,2XW22@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_9654337_0	1120972.AUMH01000011_gene164	2.081e-115	387.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,277WB@186823|Alicyclobacillaceae	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
YHH1_k127_9654337_3	138119.DSY2203	0.000972	51.0	COG3584@1|root,COG3584@2|Bacteria,1UUYS@1239|Firmicutes,25HX1@186801|Clostridia,265UW@186807|Peptococcaceae	186801|Clostridia	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
YHH1_k127_9654337_2	1121085.AUCI01000014_gene327	4.267e-19	101.0	COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus	91061|Bacilli	M	COG1388 FOG LysM repeat	-	-	-	ko:K19224	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	NLPC_P60,PG_binding_1,SH3_3
YHH1_k127_9654337_1	720554.Clocl_1543	1.04e-22	111.0	COG2382@1|root,COG2866@1|root,COG3266@1|root,COG3693@1|root,COG2382@2|Bacteria,COG2866@2|Bacteria,COG3266@2|Bacteria,COG3693@2|Bacteria,1UHTC@1239|Firmicutes,248KD@186801|Clostridia	186801|Clostridia	G	PFAM glycoside hydrolase, family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM9_1,CBM_4_9,Glyco_hydro_10,Polysacc_deac_1,SLH
YHH1_k127_9787754_2	521045.Kole_1035	1.019e-35	146.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_9787754_1	98439.AJLL01000023_gene850	4.392e-51	195.0	COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH1_k127_9787754_0	686340.Metal_1390	1.844e-65	237.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1XEKR@135618|Methylococcales	135618|Methylococcales	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
## 677 queries scanned
## Total time (seconds): 8.132760286331177
## Rate: 83.24 q/s