## Wed Dec 17 07:10:45 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/YHH2_bin.31.fa -m mmseqs --itype genome -o YHH2_bin.31 --output_dir /data/result/bins/wyx/egg/YHH2_bin.31 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YHH2_k127_10122508_0	338969.Rfer_0150	4.736e-138	448.0	COG4335@1|root,COG4335@2|Bacteria,1P0C1@1224|Proteobacteria,2VISN@28216|Betaproteobacteria,4ADJS@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation,HEAT
YHH2_k127_10122508_7	1120999.JONM01000021_gene108	0.000122	50.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,2KSSW@206351|Neisseriales	206351|Neisseriales	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
YHH2_k127_10122508_3	1123393.KB891316_gene1544	2.515e-68	236.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,2VS8Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
YHH2_k127_10122508_5	1122918.KB907247_gene4931	8.689e-37	147.0	2D0TH@1|root,32T97@2|Bacteria,1VIUA@1239|Firmicutes,4HQMN@91061|Bacilli,26YTJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10122508_1	338969.Rfer_4107	2.143e-94	313.0	COG4832@1|root,COG4832@2|Bacteria,1RBGY@1224|Proteobacteria,2VUX7@28216|Betaproteobacteria,4AHGU@80864|Comamonadaceae	28216|Betaproteobacteria	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
YHH2_k127_10122508_4	509191.AEDB02000094_gene4169	5.862e-48	174.0	COG1670@1|root,COG5646@1|root,COG1670@2|Bacteria,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,24K4J@186801|Clostridia,3WKGY@541000|Ruminococcaceae	186801|Clostridia	J	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
YHH2_k127_10122508_2	1485544.JQKP01000003_gene90	3.48e-70	241.0	COG3832@1|root,COG3832@2|Bacteria,1PGBT@1224|Proteobacteria,2W4RC@28216|Betaproteobacteria,44WN3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YHH2_k127_10122508_6	1331060.RLDS_11260	1.883e-17	81.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10124910_4	580332.Slit_2979	1.143e-257	799.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,44V20@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
YHH2_k127_10124910_1	580332.Slit_2978	0.0	1097.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,44VF7@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YHH2_k127_10124910_6	1485544.JQKP01000002_gene1535	6.215e-207	649.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria,44VKF@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YHH2_k127_10124910_36	580332.Slit_2860	1.155e-65	226.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2VSD7@28216|Betaproteobacteria,44VU2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
YHH2_k127_10124910_0	1485544.JQKP01000002_gene1533	0.0	1621.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,44V7J@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
YHH2_k127_10124910_30	580332.Slit_2862	4.303e-92	305.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,2VQ18@28216|Betaproteobacteria,44W9Q@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
YHH2_k127_10124910_46	395494.Galf_1298	1.435e-38	148.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
YHH2_k127_10124910_60	292415.Tbd_1597	8.348e-16	86.0	COG5581@1|root,COG5581@2|Bacteria,1MX00@1224|Proteobacteria,2VQEK@28216|Betaproteobacteria,1KRTQ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Flagellar regulator YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR
YHH2_k127_10124910_63	1163617.SCD_n02938	2.043e-09	68.0	COG5581@1|root,COG5581@2|Bacteria,1MX00@1224|Proteobacteria,2VQEK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility	ycgR	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR
YHH2_k127_10124910_7	1163617.SCD_n02005	4.066e-204	647.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2VJWM@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
YHH2_k127_10124910_10	580332.Slit_2866	7.295e-195	609.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria,44V4U@713636|Nitrosomonadales	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH2_k127_10124910_51	580332.Slit_2869	1.603e-36	139.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VV0X@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
YHH2_k127_10124910_45	580332.Slit_2870	7.64e-42	156.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
YHH2_k127_10124910_15	580332.Slit_2871	4.893e-145	463.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,44VCX@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
YHH2_k127_10124910_33	1049564.TevJSym_bj00060	1.083e-73	263.0	COG1216@1|root,COG3307@1|root,COG1216@2|Bacteria,COG3307@2|Bacteria,1QU2Q@1224|Proteobacteria,1T1NF@1236|Gammaproteobacteria,1JC2J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	waaE	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glyco_transf_7C,Glycos_transf_2
YHH2_k127_10124910_25	1049564.TevJSym_bj00070	9.721e-116	380.0	COG1215@1|root,COG1215@2|Bacteria,1R8C3@1224|Proteobacteria,1RYY8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
YHH2_k127_10124910_48	319225.Plut_1795	4.01e-38	151.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	TMP_2,Tape_meas_lam_C
YHH2_k127_10124910_13	395494.Galf_2821	6.046e-163	514.0	COG1216@1|root,COG1216@2|Bacteria,1N0NV@1224|Proteobacteria,2VJG7@28216|Betaproteobacteria,44VHD@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH2_k127_10124910_21	395494.Galf_2822	6.568e-120	393.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,2VKUI@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase family 2	lgtF	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
YHH2_k127_10124910_2	580332.Slit_2880	2.723e-318	983.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,44VNM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM polysaccharide biosynthesis protein CapD	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
YHH2_k127_10124910_19	580332.Slit_2881	6.259e-126	411.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,2VNAG@28216|Betaproteobacteria,44VBI@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM Glycosyl transferase, family 4, conserved region	wbiH	-	-	ko:K13007	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
YHH2_k127_10124910_24	1485544.JQKP01000002_gene1472	5.745e-116	381.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,2VJHC@28216|Betaproteobacteria,44VIG@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Male sterility protein	wbiG	-	1.1.1.219,5.1.3.2	ko:K00091,ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH2_k127_10124910_27	1390370.O203_17715	2.719e-111	374.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,1RXFQ@1236|Gammaproteobacteria,1YK5Z@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10124910_34	1132855.KB913035_gene1654	3.757e-73	258.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.412,5.1.3.26	ko:K19997,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
YHH2_k127_10124910_57	1042877.GQS_06820	3.885e-21	104.0	COG1216@1|root,arCOG01383@2157|Archaea,2Y7ZJ@28890|Euryarchaeota,244B8@183968|Thermococci	183968|Thermococci	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH2_k127_10124910_56	435590.BVU_4033	8.739e-22	111.0	2DY8I@1|root,348MR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10124910_40	926561.KB900617_gene2131	1.93e-53	198.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,3WAKF@53433|Halanaerobiales	186801|Clostridia	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
YHH2_k127_10124910_43	293826.Amet_0505	2.012e-48	183.0	COG3836@1|root,COG3836@2|Bacteria,1UZZG@1239|Firmicutes,24DTX@186801|Clostridia,36JVT@31979|Clostridiaceae	186801|Clostridia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
YHH2_k127_10124910_61	1320556.AVBP01000014_gene955	1.016e-14	85.0	COG0546@1|root,COG0546@2|Bacteria,1RB0Z@1224|Proteobacteria,2U5DF@28211|Alphaproteobacteria,43HJ1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH2_k127_10124910_18	93059.P9211_12991	7.374e-128	419.0	COG1148@1|root,COG1148@2|Bacteria,1GQJE@1117|Cyanobacteria,1MPPD@1212|Prochloraceae	1117|Cyanobacteria	C	Iron-Sulfur binding protein C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,LdpA_C
YHH2_k127_10124910_17	1280001.BAOA01000021_gene718	3.793e-130	434.0	COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,1RPPW@1236|Gammaproteobacteria,1XY9B@135623|Vibrionales	135623|Vibrionales	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
YHH2_k127_10124910_52	1122135.KB893157_gene134	9.382e-36	155.0	2BVX6@1|root,2ZUCC@2|Bacteria,1P71W@1224|Proteobacteria,2UW2Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10124910_38	1121456.ATVA01000017_gene112	1.098e-61	237.0	COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,435YN@68525|delta/epsilon subdivisions,2X0FJ@28221|Deltaproteobacteria,2MC5W@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	nahM	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
YHH2_k127_10124910_44	1123503.KB908056_gene1310	1.465e-45	179.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TVTA@28211|Alphaproteobacteria,2KK27@204458|Caulobacterales	204458|Caulobacterales	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
YHH2_k127_10124910_55	1123503.KB908056_gene1309	1.114e-31	136.0	2941A@1|root,2ZRG3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10124910_54	351160.RCIX2497	3.686e-32	133.0	COG0500@1|root,arCOG01791@2157|Archaea	2157|Archaea	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH2_k127_10124910_35	1123503.KB908056_gene1308	1.859e-69	250.0	COG0151@1|root,COG0151@2|Bacteria,1NA76@1224|Proteobacteria,2TY9E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
YHH2_k127_10124910_59	243232.MJ_1062	6.799e-20	101.0	COG3980@1|root,arCOG06581@2157|Archaea,2XZ5T@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM acylneuraminate cytidylyltransferase	neuA	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3,Glyco_tran_28_C
YHH2_k127_10124910_16	318161.Sden_1289	1.821e-133	433.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,2QAT6@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM N-acetylneuraminic acid synthase	-	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
YHH2_k127_10124910_65	1205680.CAKO01000038_gene1840	2.388e-05	49.0	2E3ZS@1|root,32YWP@2|Bacteria,1NAZV@1224|Proteobacteria,2UGW3@28211|Alphaproteobacteria,2JXCF@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10124910_3	1122135.KB893157_gene132	4.617e-272	848.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
YHH2_k127_10124910_32	63737.Npun_R0688	1.739e-82	280.0	COG1861@1|root,COG1861@2|Bacteria,1GDG8@1117|Cyanobacteria,1HNRU@1161|Nostocales	1117|Cyanobacteria	H	PFAM acylneuraminate cytidylyltransferase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
YHH2_k127_10124910_23	1201288.M900_0060	6.317e-119	396.0	COG0399@1|root,COG1091@1|root,COG0399@2|Bacteria,COG1091@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
YHH2_k127_10124910_37	1201288.M900_0060	2.802e-62	225.0	COG0399@1|root,COG1091@1|root,COG0399@2|Bacteria,COG1091@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
YHH2_k127_10124910_11	1001585.MDS_1966	6.117e-176	555.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1YDA8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00362	R00291	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Polysacc_synt_2
YHH2_k127_10124910_8	331678.Cphamn1_0373	2.779e-203	647.0	COG1132@1|root,COG1132@2|Bacteria,1FDNB@1090|Chlorobi	1090|Chlorobi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH2_k127_10124910_42	580332.Slit_2904	1.007e-50	182.0	COG1846@1|root,COG1846@2|Bacteria,1N0TY@1224|Proteobacteria,2VV7T@28216|Betaproteobacteria,44WI6@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
YHH2_k127_10124910_22	1485544.JQKP01000002_gene1539	3.655e-119	392.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2VPK7@28216|Betaproteobacteria,44WH1@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaC	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH2_k127_10124910_9	580332.Slit_2906	7.399e-202	635.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,44VI0@713636|Nitrosomonadales	28216|Betaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
YHH2_k127_10124910_5	580332.Slit_2907	7.263e-213	663.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,44V4M@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd,dTDP_sugar_isom
YHH2_k127_10124910_12	1485544.JQKP01000001_gene1328	2.39e-163	516.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2VHA6@28216|Betaproteobacteria,44VIN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YHH2_k127_10124910_29	580332.Slit_2910	1.164e-99	333.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,44VRT@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
YHH2_k127_10124910_20	580332.Slit_2911	8.868e-126	409.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2VI50@28216|Betaproteobacteria,44VGA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
YHH2_k127_10124910_31	1116472.MGMO_133c00080	2.16e-84	282.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,1RRGB@1236|Gammaproteobacteria,1XGG9@135618|Methylococcales	135618|Methylococcales	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10124910_41	1116472.MGMO_133c00090	4.423e-53	190.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
YHH2_k127_10124910_28	1116472.MGMO_133c00110	8.278e-111	366.0	COG0702@1|root,COG0702@2|Bacteria,1PGNB@1224|Proteobacteria,1RUX3@1236|Gammaproteobacteria,1XFGR@135618|Methylococcales	135618|Methylococcales	GM	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3,NAD_binding_10
YHH2_k127_10124910_50	1116472.MGMO_133c00120	6.105e-37	142.0	COG0702@1|root,COG0702@2|Bacteria,1N5CF@1224|Proteobacteria	1224|Proteobacteria	GM	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3
YHH2_k127_10124910_39	1116472.MGMO_133c00130	6.764e-56	201.0	COG5528@1|root,COG5528@2|Bacteria,1RDUE@1224|Proteobacteria,1S5XB@1236|Gammaproteobacteria,1XFJB@135618|Methylococcales	135618|Methylococcales	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
YHH2_k127_10124910_14	395494.Galf_2862	5.446e-155	491.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,44VJP@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
YHH2_k127_10124910_58	395494.Galf_2861	4.097e-20	91.0	COG3313@1|root,COG3313@2|Bacteria,1Q968@1224|Proteobacteria,2WCHA@28216|Betaproteobacteria,44W3E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
YHH2_k127_10124910_53	76114.ebA6332	2.491e-32	139.0	COG3012@1|root,COG3012@2|Bacteria,1QU5B@1224|Proteobacteria,2WGSX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
YHH2_k127_10124910_49	745411.B3C1_08938	3.102e-37	143.0	COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,1SCG7@1236|Gammaproteobacteria,1J6W6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Fe-S-cluster oxidoreductase	yeiW	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
YHH2_k127_10124910_64	1027273.GZ77_21195	6.132e-08	53.0	COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,1S6AM@1236|Gammaproteobacteria,1XPSI@135619|Oceanospirillales	135619|Oceanospirillales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_10160431_3	357808.RoseRS_3212	3.821e-76	261.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
YHH2_k127_10160431_2	1121382.JQKG01000080_gene894	1.766e-89	325.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_10160431_7	1313301.AUGC01000003_gene2034	1.108e-13	77.0	COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
YHH2_k127_10160431_1	580332.Slit_2948	4.871e-234	730.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria,44V7Q@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
YHH2_k127_10160431_4	580332.Slit_2949	1.42e-46	168.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,2VTYU@28216|Betaproteobacteria,44W0N@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	yggX	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
YHH2_k127_10160431_0	580332.Slit_2950	0.0	1319.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,44V8M@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
YHH2_k127_10160431_5	580332.Slit_2951	8.571e-35	137.0	2E4XE@1|root,32ZRB@2|Bacteria,1N7HI@1224|Proteobacteria,2VVPN@28216|Betaproteobacteria,44W23@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10160431_6	580332.Slit_2952	2.813e-33	131.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,44W0G@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
YHH2_k127_10169446_2	580332.Slit_2423	2.35e-310	961.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,44W7Y@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
YHH2_k127_10169446_5	580332.Slit_2424	5.369e-162	513.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VJKH@28216|Betaproteobacteria,44W6Q@713636|Nitrosomonadales	28216|Betaproteobacteria	KO	PFAM cobalamin synthesis protein P47K	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
YHH2_k127_10169446_10	322710.Avin_50490	6.916e-41	153.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1S5WG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
YHH2_k127_10169446_6	580332.Slit_2426	7.957e-124	405.0	COG0374@1|root,COG0374@2|Bacteria,1R6ND@1224|Proteobacteria,2VQXM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Ni,Fe-hydrogenase I large subunit	hoxV	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
YHH2_k127_10169446_13	62928.azo3797	1.038e-29	124.0	COG1773@1|root,COG1773@2|Bacteria,1N813@1224|Proteobacteria,2VUNU@28216|Betaproteobacteria,2KXFP@206389|Rhodocyclales	206389|Rhodocyclales	C	[NiFe]-hydrogenase assembly, chaperone, HybE	-	-	-	-	-	-	-	-	-	-	-	-	NiFe-hyd_HybE
YHH2_k127_10169446_14	1348657.M622_19285	1.066e-25	110.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2VJ2W@28216|Betaproteobacteria,2KY8S@206389|Rhodocyclales	1224|Proteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
YHH2_k127_10169446_15	511.JT27_01385	9.201e-16	78.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VIPG@28216|Betaproteobacteria,3T2YW@506|Alcaligenaceae	28216|Betaproteobacteria	L	Arm DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
YHH2_k127_10169446_1	580332.Slit_1466	0.0	1021.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,44V7R@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
YHH2_k127_10169446_12	292563.Cyast_0296	1.569e-32	130.0	COG0399@1|root,COG0399@2|Bacteria,1G88E@1117|Cyanobacteria	1117|Cyanobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YHH2_k127_10169446_3	580332.Slit_1465	5.457e-295	908.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,44VBE@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
YHH2_k127_10169446_0	580332.Slit_1462	0.0	1807.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,44V0B@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YHH2_k127_10169446_8	580332.Slit_1461	3.973e-84	280.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria,44VQN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
YHH2_k127_10169446_4	580332.Slit_1518	3.875e-244	762.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2VM3G@28216|Betaproteobacteria,44W8Z@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
YHH2_k127_10169446_9	580332.Slit_1517	1.067e-76	261.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2VRJE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
YHH2_k127_10177940_16	1331060.RLDS_11260	5.574e-18	83.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10177940_13	1162668.LFE_0348	4.39e-22	97.0	2DNZI@1|root,32ZX6@2|Bacteria	2|Bacteria	S	TIGRFAM YgiT-type zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	MqsA_antitoxin
YHH2_k127_10177940_20	697282.Mettu_2666	5.974e-10	62.0	COG2161@1|root,COG2161@2|Bacteria,1N8QY@1224|Proteobacteria,1SFWC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_10177940_7	1485544.JQKP01000001_gene1148	3.172e-55	195.0	2APBK@1|root,32XZ2@2|Bacteria,1N4U2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10177940_15	272123.Anacy_5484	1.529e-18	89.0	2CCMX@1|root,330YA@2|Bacteria,1G7SD@1117|Cyanobacteria,1HPDF@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10177940_6	580332.Slit_2272	4.954e-98	324.0	COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,2VV8V@28216|Betaproteobacteria,44W5D@713636|Nitrosomonadales	28216|Betaproteobacteria	O	SMART Prolyl 4-hydroxylase alpha subunit	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
YHH2_k127_10177940_10	580332.Slit_2267	5.489e-26	107.0	COG4728@1|root,COG4728@2|Bacteria,1NEUX@1224|Proteobacteria,2VX3S@28216|Betaproteobacteria,44W2S@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
YHH2_k127_10177940_3	580332.Slit_2279	1.853e-242	753.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,44V5T@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH2_k127_10177940_8	87626.PTD2_05625	4.666e-49	187.0	COG0657@1|root,COG0657@2|Bacteria,1NIHV@1224|Proteobacteria	1224|Proteobacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
YHH2_k127_10177940_5	580332.Slit_2280	1.218e-156	497.0	COG0240@1|root,COG0240@2|Bacteria,1RED0@1224|Proteobacteria,2W2AD@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
YHH2_k127_10177940_0	580332.Slit_0924	0.0	1692.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2VJK5@28216|Betaproteobacteria	28216|Betaproteobacteria	G	pyruvate phosphate dikinase	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH2_k127_10177940_9	877455.Metbo_1709	8.16e-34	135.0	arCOG03571@1|root,arCOG03571@2157|Archaea,2Y1I5@28890|Euryarchaeota,23PT8@183925|Methanobacteria	183925|Methanobacteria	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
YHH2_k127_10177940_4	743299.Acife_1154	2.782e-198	624.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1T97N@1236|Gammaproteobacteria,2NE01@225057|Acidithiobacillales	225057|Acidithiobacillales	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH2_k127_10177940_22	1163617.SCD_n00910	5.125e-08	57.0	COG1669@1|root,COG1669@2|Bacteria,1N9WC@1224|Proteobacteria,2VY03@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH2_k127_10177940_17	870187.Thini_2241	2.915e-17	85.0	COG4691@1|root,COG4691@2|Bacteria,1QN0Q@1224|Proteobacteria,1SFGU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Plasmid stability protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10177940_18	211165.AJLN01000084_gene1826	1.822e-15	79.0	2E9PK@1|root,333W0@2|Bacteria,1GIZ8@1117|Cyanobacteria,1JMPM@1189|Stigonemataceae	1117|Cyanobacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
YHH2_k127_10177940_14	211165.AJLN01000084_gene1827	1.908e-19	89.0	COG5428@1|root,COG5428@2|Bacteria,1GKRU@1117|Cyanobacteria,1JMMJ@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
YHH2_k127_10177940_19	870187.Thini_2241	1.376e-14	77.0	COG4691@1|root,COG4691@2|Bacteria,1QN0Q@1224|Proteobacteria,1SFGU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Plasmid stability protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10177940_11	1163617.SCD_n01379	5.832e-26	110.0	COG1669@1|root,COG1669@2|Bacteria,1N9WC@1224|Proteobacteria,2VY03@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH2_k127_10177940_12	1163617.SCD_n01378	3.099e-22	102.0	COG2250@1|root,COG2250@2|Bacteria,1NGJT@1224|Proteobacteria,2W5VI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
YHH2_k127_10177940_23	290317.Cpha266_2645	0.0001627	48.0	arCOG07672@1|root,3290P@2|Bacteria,1FFJ3@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
YHH2_k127_10177940_21	28152.DJ57_773	9.282e-09	65.0	COG2944@1|root,COG2944@2|Bacteria,1N75U@1224|Proteobacteria,1SCEY@1236|Gammaproteobacteria,41G4R@629|Yersinia	1236|Gammaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
YHH2_k127_10177940_1	582744.Msip34_1393	1.243e-307	951.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2VKZP@28216|Betaproteobacteria,2KKYX@206350|Nitrosomonadales	206350|Nitrosomonadales	CI	TIGRFAM oxaloacetate decarboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
YHH2_k127_10177940_2	582744.Msip34_1392	7.782e-259	800.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2WH9U@28216|Betaproteobacteria,2KME4@206350|Nitrosomonadales	206350|Nitrosomonadales	I	PFAM Carbamoyl-phosphate synthase L chain	-	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YHH2_k127_10206913_0	580332.Slit_1806	0.0	1236.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria,44WD2@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Carbohydrate phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
YHH2_k127_10275597_9	580332.Slit_2760	2.516e-139	444.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,44V5T@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH2_k127_10275597_15	580332.Slit_2495	8.29e-88	295.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,2VPKX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome c-type protein	napC	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
YHH2_k127_10275597_24	497321.C664_09898	1.895e-41	155.0	2DMM5@1|root,32SCB@2|Bacteria,1N151@1224|Proteobacteria,2VUSG@28216|Betaproteobacteria,2KWVB@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10275597_1	62928.azo1149	0.0	1019.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,2KVZ5@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
YHH2_k127_10275597_25	305700.B447_07162	4.205e-37	142.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,2VUFA@28216|Betaproteobacteria,2KX0Q@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
YHH2_k127_10275597_14	580332.Slit_2503	1.986e-90	316.0	COG0847@1|root,COG0847@2|Bacteria,1RCPS@1224|Proteobacteria,2WEVE@28216|Betaproteobacteria,44WB3@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Exonuclease RNase T and DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
YHH2_k127_10275597_0	580332.Slit_2504	0.0	1063.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,44WEE@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART CBS domain containing protein	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
YHH2_k127_10275597_3	1163617.SCD_n00142	7.262e-219	685.0	COG0477@1|root,COG2814@2|Bacteria,1R2KY@1224|Proteobacteria,2VI3X@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH2_k127_10275597_11	1458357.BG58_18255	2.452e-119	387.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2VP0A@28216|Betaproteobacteria,1K90G@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
YHH2_k127_10275597_23	296591.Bpro_3936	2.113e-48	176.0	COG1553@1|root,COG1553@2|Bacteria,1RDFR@1224|Proteobacteria,2VSFK@28216|Betaproteobacteria,4AFYB@80864|Comamonadaceae	28216|Betaproteobacteria	P	DsrE/DsrF-like family	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
YHH2_k127_10275597_16	381666.H16_A2208	1.738e-84	285.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,2VI9S@28216|Betaproteobacteria,1K7KF@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
YHH2_k127_10275597_19	580332.Slit_0149	6.502e-68	232.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria,44WH5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SMART CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
YHH2_k127_10275597_8	580332.Slit_0148	6.729e-151	480.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,44V70@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
YHH2_k127_10275597_13	580332.Slit_0147	1.501e-114	370.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria,44VRV@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
YHH2_k127_10275597_7	580332.Slit_0146	1.076e-163	526.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,44VAD@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH2_k127_10275597_20	580332.Slit_0145	5.513e-61	217.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,44UYU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
YHH2_k127_10275597_6	580332.Slit_0145	4.758e-169	534.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,44UYU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
YHH2_k127_10275597_21	580332.Slit_0144	1.081e-55	197.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2WEX0@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH2_k127_10275597_22	580332.Slit_0143	2.686e-50	180.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,2VU52@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Rhodanese domain protein	pspE2	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH2_k127_10275597_12	580332.Slit_0141	1.205e-114	378.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,44VIA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
YHH2_k127_10275597_5	1485544.JQKP01000002_gene1503	5.133e-173	550.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,44VDN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
YHH2_k127_10275597_2	580332.Slit_0139	5.69e-312	968.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,44VBN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
YHH2_k127_10275597_17	580332.Slit_0138	2.144e-80	272.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria,44VW1@713636|Nitrosomonadales	28216|Betaproteobacteria	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
YHH2_k127_10275597_10	580332.Slit_0137	1.903e-133	431.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,44VN9@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
YHH2_k127_10275597_4	580332.Slit_0136	4.428e-214	666.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,44VNI@713636|Nitrosomonadales	28216|Betaproteobacteria	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH2_k127_10275597_26	580332.Slit_0135	8.055e-05	46.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,44VZT@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
YHH2_k127_10292534_6	580332.Slit_0046	2.9e-145	462.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,44VMI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
YHH2_k127_10292534_8	580332.Slit_0047	2.164e-102	338.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,44V8V@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Nucleotidyl transferase	rmlA	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
YHH2_k127_10292534_16	697282.Mettu_4249	1.633e-34	134.0	2DVNB@1|root,32UZS@2|Bacteria,1N65J@1224|Proteobacteria,1SF9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10292534_10	1255043.TVNIR_0889	7.049e-89	309.0	COG2199@1|root,COG2703@1|root,COG2703@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S5H1@1236|Gammaproteobacteria,1X16Q@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
YHH2_k127_10292534_4	580332.Slit_0048	8.637e-228	712.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,44VB9@713636|Nitrosomonadales	28216|Betaproteobacteria	E	peptidase M24B X-Pro dipeptidase aminopeptidase domain protein	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
YHH2_k127_10292534_5	580332.Slit_0049	1.64e-199	627.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,44V7V@713636|Nitrosomonadales	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
YHH2_k127_10292534_20	1249627.D779_2407	3.154e-24	106.0	2DQ0J@1|root,3348C@2|Bacteria,1NBQ2@1224|Proteobacteria,1SPMC@1236|Gammaproteobacteria,1X1A6@135613|Chromatiales	135613|Chromatiales	S	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
YHH2_k127_10292534_15	580332.Slit_0051	1.003e-42	160.0	COG0840@1|root,COG0840@2|Bacteria,1NKHI@1224|Proteobacteria,2WHPN@28216|Betaproteobacteria,44W48@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
YHH2_k127_10292534_3	395494.Galf_0057	1.144e-253	786.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,44V06@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH2_k127_10292534_11	580332.Slit_0053	7.304e-66	226.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2VSWS@28216|Betaproteobacteria,44VXF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
YHH2_k127_10292534_13	395494.Galf_0063	7.56e-64	222.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,44WGS@713636|Nitrosomonadales	28216|Betaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
YHH2_k127_10292534_7	580332.Slit_0058	4.903e-136	435.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,44VE1@713636|Nitrosomonadales	28216|Betaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
YHH2_k127_10292534_17	1283300.ATXB01000001_gene417	1.048e-30	124.0	COG3668@1|root,COG3668@2|Bacteria,1PZK0@1224|Proteobacteria,1THTB@1236|Gammaproteobacteria,1XFN3@135618|Methylococcales	135618|Methylococcales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_10292534_25	1173028.ANKO01000088_gene25	2.365e-12	68.0	2E4QQ@1|root,32ZJA@2|Bacteria,1G97D@1117|Cyanobacteria,1HD55@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10292534_23	331678.Cphamn1_1907	6.14e-20	96.0	2DNRM@1|root,32YT2@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH2_k127_10292534_26	497964.CfE428DRAFT_1563	5.319e-12	68.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_10292534_19	522306.CAP2UW1_2579	1.057e-26	110.0	COG1598@1|root,COG1598@2|Bacteria,1NDHG@1224|Proteobacteria,2VWK1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10292534_0	395494.Galf_0065	0.0	2163.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,44V3A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Vitamin B12 dependent methionine synthase activation region	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
YHH2_k127_10292534_18	1123368.AUIS01000019_gene1228	1.365e-30	129.0	2DNNV@1|root,32YCB@2|Bacteria,1N7IN@1224|Proteobacteria,1S9V9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM CcdB protein	ccdB	-	-	ko:K19163	-	-	-	-	ko00000,ko02048	-	-	-	CcdB
YHH2_k127_10292534_21	404380.Gbem_2487	1.002e-21	96.0	COG5302@1|root,COG5302@2|Bacteria	2|Bacteria	S	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	-	-	-	ko:K19164	-	-	-	-	ko00000,ko02048	-	-	-	CcdA
YHH2_k127_10292534_2	1163617.SCD_n00399	8.037e-255	790.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,2VJ62@28216|Betaproteobacteria	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH2_k127_10292534_9	1278309.KB907105_gene1475	1.807e-92	310.0	COG2199@1|root,COG3706@2|Bacteria,1R592@1224|Proteobacteria,1RZST@1236|Gammaproteobacteria,1XR6C@135619|Oceanospirillales	135619|Oceanospirillales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
YHH2_k127_10292534_24	640081.Dsui_0536	1.068e-16	89.0	COG2703@1|root,COG4191@1|root,COG2703@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KVY4@206389|Rhodocyclales	206389|Rhodocyclales	PT	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Hemerythrin,HisKA
YHH2_k127_10292534_1	580332.Slit_0062	7.2e-285	880.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,44V3K@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH2_k127_10292534_22	580332.Slit_0063	1.176e-20	94.0	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,2VVR4@28216|Betaproteobacteria,44W3N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Membrane fusogenic activity	yqiC	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
YHH2_k127_10292534_14	395494.Galf_0069	1.924e-44	169.0	2C5U9@1|root,30FF7@2|Bacteria,1N2U0@1224|Proteobacteria,2WIIE@28216|Betaproteobacteria,44VV4@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
YHH2_k127_10292534_12	1485544.JQKP01000001_gene904	4.358e-64	220.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,44VUX@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
YHH2_k127_10303501_1	580332.Slit_2472	2.292e-116	379.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSTA@28216|Betaproteobacteria,44W6B@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
YHH2_k127_10303501_2	580332.Slit_2473	1.128e-74	252.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,44VTK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
YHH2_k127_10303501_3	580332.Slit_2568	4.811e-40	154.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Di-haem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
YHH2_k127_10303501_0	580332.Slit_2569	9.674e-205	646.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria,44V11@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
YHH2_k127_10333184_23	580332.Slit_2310	1.81e-56	201.0	COG3103@1|root,COG3103@2|Bacteria,1N6AX@1224|Proteobacteria,2VVME@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4
YHH2_k127_10333184_7	580332.Slit_2309	3.643e-125	407.0	COG4783@1|root,COG4783@2|Bacteria,1R84W@1224|Proteobacteria,2VIBK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH2_k127_10333184_15	580332.Slit_2201	7.663e-96	317.0	COG0349@1|root,COG0349@2|Bacteria,1REMB@1224|Proteobacteria,2VQQC@28216|Betaproteobacteria,44WFH@713636|Nitrosomonadales	28216|Betaproteobacteria	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
YHH2_k127_10333184_4	580332.Slit_2199	1.194e-170	543.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,44VGY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the radical SAM superfamily. RlmN family	rlmN_2	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
YHH2_k127_10333184_20	1244869.H261_18085	6.373e-86	290.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2TRTM@28211|Alphaproteobacteria,2JRPE@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
YHH2_k127_10333184_24	580332.Slit_2197	9.822e-55	197.0	COG2932@1|root,COG2932@2|Bacteria,1NBZE@1224|Proteobacteria	1224|Proteobacteria	K	PFAM Peptidase S24 S26A S26B, conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
YHH2_k127_10333184_38	395494.Galf_2609	6.695e-20	91.0	COG3668@1|root,COG3668@2|Bacteria,1PJWP@1224|Proteobacteria,2W88C@28216|Betaproteobacteria,44WJ0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_10333184_40	395494.Galf_2609	3.095e-17	84.0	COG3668@1|root,COG3668@2|Bacteria,1PJWP@1224|Proteobacteria,2W88C@28216|Betaproteobacteria,44WJ0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_10333184_27	580332.Slit_1213	1.124e-45	166.0	COG2161@1|root,COG2161@2|Bacteria,1NEWX@1224|Proteobacteria,2WCQS@28216|Betaproteobacteria,44WIC@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_10333184_35	251221.35211584	9.915e-28	120.0	29ZEJ@1|root,33BE0@2|Bacteria,1GRB7@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10333184_8	251221.35211585	9.372e-123	409.0	COG1479@1|root,COG1479@2|Bacteria,1G3QA@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
YHH2_k127_10333184_32	580332.Slit_2235	3.266e-31	128.0	2EK34@1|root,33DTI@2|Bacteria,1NGT0@1224|Proteobacteria,2W5UJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
YHH2_k127_10333184_41	261292.Nit79A3_0186	3.694e-09	61.0	2C6B2@1|root,335GA@2|Bacteria,1NG8G@1224|Proteobacteria,2W4E3@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10333184_33	317936.Nos7107_2981	6.384e-30	121.0	COG2929@1|root,COG2929@2|Bacteria,1G92M@1117|Cyanobacteria,1HSNE@1161|Nostocales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_10333184_30	580332.Slit_2183	2.402e-34	133.0	2ECSY@1|root,336QI@2|Bacteria,1N9AZ@1224|Proteobacteria,2VYWR@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10333184_26	882378.RBRH_01979	4.655e-51	188.0	COG1848@1|root,COG1848@2|Bacteria,1N8W5@1224|Proteobacteria,2VXAH@28216|Betaproteobacteria,1K8NT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_10333184_36	882378.RBRH_01980	7.244e-27	111.0	COG2336@1|root,COG2336@2|Bacteria,1NG5I@1224|Proteobacteria,2VW4X@28216|Betaproteobacteria,1K993@119060|Burkholderiaceae	28216|Betaproteobacteria	T	SpoVT / AbrB like domain	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_10333184_17	1449076.JOOE01000002_gene1161	3.736e-88	301.0	COG2340@1|root,COG2340@2|Bacteria,1RJVF@1224|Proteobacteria,2UR9T@28211|Alphaproteobacteria,2K30R@204457|Sphingomonadales	204457|Sphingomonadales	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
YHH2_k127_10333184_28	1123367.C666_14475	1.33e-45	169.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2VSUJ@28216|Betaproteobacteria,2KWMV@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
YHH2_k127_10333184_5	748247.AZKH_1543	3.076e-160	517.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VHE6@28216|Betaproteobacteria,2KVS3@206389|Rhodocyclales	206389|Rhodocyclales	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH2_k127_10333184_39	748247.AZKH_1543	1.648e-19	89.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VHE6@28216|Betaproteobacteria,2KVS3@206389|Rhodocyclales	206389|Rhodocyclales	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH2_k127_10333184_0	580332.Slit_2319	0.0	1019.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2VIV3@28216|Betaproteobacteria,44VP9@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
YHH2_k127_10333184_37	631362.Thi970DRAFT_00075	8.084e-27	111.0	COG1598@1|root,COG1598@2|Bacteria,1NC35@1224|Proteobacteria,1SRZV@1236|Gammaproteobacteria,1X1FP@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10333184_31	269799.Gmet_1322	5.381e-34	132.0	COG1724@1|root,COG1724@2|Bacteria,1N5JA@1224|Proteobacteria,431UH@68525|delta/epsilon subdivisions,2WWQR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_10333184_34	580332.Slit_2318	1.734e-29	118.0	COG2501@1|root,COG2501@2|Bacteria,1N7NW@1224|Proteobacteria,2VVQY@28216|Betaproteobacteria,44W1T@713636|Nitrosomonadales	28216|Betaproteobacteria	S	S4 domain	ybcJ	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
YHH2_k127_10333184_21	580332.Slit_2317	3.422e-66	227.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2VSE7@28216|Betaproteobacteria,44VZB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM Class I peptide chain release factor	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
YHH2_k127_10333184_13	580332.Slit_1246	6.625e-98	322.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria,44VRH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
YHH2_k127_10333184_11	580332.Slit_2518	1.11e-101	340.0	COG3021@1|root,COG3021@2|Bacteria	2|Bacteria	S	interspecies interaction between organisms	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH2_k127_10333184_14	580332.Slit_2316	3.904e-97	332.0	COG4912@1|root,COG4912@2|Bacteria,1PX21@1224|Proteobacteria,2WCJR@28216|Betaproteobacteria,44W8K@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YHH2_k127_10333184_1	580332.Slit_0939	5.736e-241	754.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,44VJF@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB_2	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
YHH2_k127_10333184_25	580332.Slit_0940	7.72e-52	196.0	COG3170@1|root,COG3170@2|Bacteria,1MWZB@1224|Proteobacteria,2VNBQ@28216|Betaproteobacteria,44VTY@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
YHH2_k127_10333184_22	580332.Slit_0941	8.359e-61	217.0	COG3147@1|root,COG3147@2|Bacteria,1R129@1224|Proteobacteria,2WHYD@28216|Betaproteobacteria,44VVT@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
YHH2_k127_10333184_16	580332.Slit_0942	3.819e-93	309.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,44VND@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
YHH2_k127_10333184_2	580332.Slit_0943	7.512e-219	683.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,44VG1@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH2_k127_10333184_9	395494.Galf_0603	1.176e-120	396.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2VHDW@28216|Betaproteobacteria,44WDZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	AI-2E family transporter	perM	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YHH2_k127_10333184_19	580332.Slit_0944	8.958e-87	301.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,44VQF@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bacterial dnaA  protein	hda	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
YHH2_k127_10333184_43	62928.azo1372	0.000877	44.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_10333184_10	580332.Slit_0946	5.208e-120	388.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,44VMB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
YHH2_k127_10333184_42	909663.KI867150_gene2800	1.356e-06	51.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,2MQYI@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Carbohydrate phosphorylase	-	-	2.4.1.1,2.4.1.11	ko:K00688,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R02111	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3,GT35	-	DUF3417,Phosphorylase
YHH2_k127_10333184_29	1121015.N789_02005	7.328e-37	144.0	2E8C6@1|root,332QU@2|Bacteria,1NBRE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10333184_3	580332.Slit_0635	5.143e-217	677.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,44V4R@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM peptidase S1 and S6 chymotrypsin Hap	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
YHH2_k127_10333184_6	580332.Slit_0636	1.874e-134	430.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,2VIX1@28216|Betaproteobacteria,44V8N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	NIF3 (NGG1p interacting factor 3)	ybgI	-	-	-	-	-	-	-	-	-	-	-	NIF3
YHH2_k127_10333184_18	292415.Tbd_1833	7.922e-88	293.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,1KRMG@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Rieske [2Fe-2S] domain	-	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
YHH2_k127_10333184_12	292415.Tbd_1832	6.037e-98	322.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,1KRDP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
YHH2_k127_10347996_1	1122139.KB907869_gene952	8.036e-56	213.0	COG0500@1|root,COG3551@1|root,COG3754@1|root,COG2226@2|Bacteria,COG3551@2|Bacteria,COG3754@2|Bacteria,1QU2J@1224|Proteobacteria,1T5RA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase WbsX	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WbsX
YHH2_k127_10347996_0	1123372.AUIT01000014_gene1589	5.004e-84	285.0	COG2227@1|root,COG2227@2|Bacteria,2GINH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10347996_2	203124.Tery_3237	5.098e-38	151.0	COG2327@1|root,COG2327@2|Bacteria	2|Bacteria	S	slime layer polysaccharide biosynthetic process	wgaD	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
YHH2_k127_10353979_4	580332.Slit_0424	2.9e-237	738.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria,44VCF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
YHH2_k127_10353979_3	395494.Galf_0272	5.104e-258	801.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,44V78@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
YHH2_k127_10353979_9	580332.Slit_0421	6.752e-68	234.0	2AG2G@1|root,3166U@2|Bacteria,1PWZ6@1224|Proteobacteria,2WCH4@28216|Betaproteobacteria,44W2R@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10353979_7	580332.Slit_0420	2.605e-98	327.0	2DB6R@1|root,2Z7I2@2|Bacteria,1R7AG@1224|Proteobacteria,2VQZS@28216|Betaproteobacteria,44VTJ@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10353979_11	580332.Slit_0419	5.826e-21	93.0	COG3197@1|root,COG3197@2|Bacteria,1PWZD@1224|Proteobacteria,2WCHB@28216|Betaproteobacteria,44W3I@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM cytochrome oxidase maturation protein cbb3-type	-	-	-	-	-	-	-	-	-	-	-	-	FixS
YHH2_k127_10353979_0	580332.Slit_0418	0.0	1381.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,44VHX@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
YHH2_k127_10353979_8	580332.Slit_0417	1.046e-83	280.0	COG5456@1|root,COG5456@2|Bacteria,1PJEG@1224|Proteobacteria,2W7Y2@28216|Betaproteobacteria,44W4G@713636|Nitrosomonadales	28216|Betaproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH
YHH2_k127_10353979_2	580332.Slit_0416	1.449e-268	831.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,44VFR@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM cytochrome c oxidase accessory protein CcoG	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
YHH2_k127_10353979_6	580332.Slit_0414	1.004e-148	475.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,44UZ6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N,OmpA
YHH2_k127_10353979_10	580332.Slit_0413	8.467e-27	110.0	2E5UC@1|root,330IN@2|Bacteria,1NAMZ@1224|Proteobacteria,2WCHC@28216|Betaproteobacteria,44W3J@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cbb3-type cytochrome oxidase component FixQ	-	-	-	-	-	-	-	-	-	-	-	-	FixQ
YHH2_k127_10353979_5	580332.Slit_0412	4.456e-162	511.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,44VF2@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome C oxidase mono-heme subunit FixO	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
YHH2_k127_10353979_1	580332.Slit_0411	3.259e-301	925.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,44V6A@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c oxidase subunit I	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
YHH2_k127_10372557_0	395494.Galf_2159	9.369e-130	418.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,44W7T@713636|Nitrosomonadales	28216|Betaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH2_k127_10372557_1	395494.Galf_2160	4.645e-97	330.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,2VIS6@28216|Betaproteobacteria,44WHI@713636|Nitrosomonadales	28216|Betaproteobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YHH2_k127_10372557_2	640081.Dsui_0410	3.568e-71	246.0	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,2KW36@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
YHH2_k127_10372654_0	580332.Slit_2311	1.171e-275	857.0	COG4252@1|root,COG4252@2|Bacteria,1R9GK@1224|Proteobacteria,2VKE8@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM CHASE2 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2
YHH2_k127_10375599_1	580332.Slit_0959	2.884e-185	580.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,44VPG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
YHH2_k127_10375599_3	580332.Slit_0960	2.882e-46	170.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,44VZC@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
YHH2_k127_10375599_0	580332.Slit_0961	0.0	1005.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,44VEI@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
YHH2_k127_10375599_2	1485544.JQKP01000005_gene351	3.394e-166	526.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,44V8I@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YHH2_k127_10394134_4	580332.Slit_2251	1.248e-77	261.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,44VHV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
YHH2_k127_10394134_7	580332.Slit_2250	1.768e-60	210.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,44VW0@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM ferredoxin, 2Fe-2S type, ISC system	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
YHH2_k127_10394134_12	580332.Slit_2249	1.707e-28	115.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,2VVQU@28216|Betaproteobacteria,44W1N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Iron-sulphur cluster assembly	iscX	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
YHH2_k127_10394134_3	580332.Slit_2248	4.419e-86	286.0	COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,2VREE@28216|Betaproteobacteria,44VV0@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein	dsbB	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
YHH2_k127_10394134_5	580332.Slit_2245	2.657e-71	248.0	COG3038@1|root,COG3038@2|Bacteria,1PIVP@1224|Proteobacteria,2W7F3@28216|Betaproteobacteria,44VYF@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
YHH2_k127_10394134_11	335283.Neut_1999	1.33e-37	143.0	COG2929@1|root,COG2929@2|Bacteria,1NE6W@1224|Proteobacteria	1224|Proteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_10394134_13	1407650.BAUB01000008_gene1759	2.734e-20	94.0	2CUP7@1|root,32SVQ@2|Bacteria,1G747@1117|Cyanobacteria,1H1YT@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10394134_1	1562701.BBOF01000021_gene421	3.084e-105	350.0	2DMX4@1|root,32U70@2|Bacteria,1Q3E6@1224|Proteobacteria,2VPMP@28216|Betaproteobacteria,1KHJS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF1910)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1910,DUF1911
YHH2_k127_10394134_0	580332.Slit_2244	1.724e-196	622.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,44V7G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
YHH2_k127_10394134_9	1485544.JQKP01000003_gene98	5.804e-49	180.0	COG3945@1|root,COG3945@2|Bacteria,1N0BD@1224|Proteobacteria,2VUY4@28216|Betaproteobacteria,44WHW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YHH2_k127_10394134_10	580332.Slit_2246	8.414e-44	162.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,44WIJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Invasion gene expression up-regulator, SirB	sirB	-	-	-	-	-	-	-	-	-	-	-	SirB
YHH2_k127_10394134_8	1485544.JQKP01000001_gene1204	6.914e-54	199.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2VJU5@28216|Betaproteobacteria,44W1J@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM HPP family protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS,HPP
YHH2_k127_10394134_6	1163617.SCD_n00367	4.983e-63	224.0	COG2863@1|root,COG2863@2|Bacteria,1R8K9@1224|Proteobacteria	1224|Proteobacteria	C	Pfam cytochrome c	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C,Cytochrome_CBB3
YHH2_k127_10394134_2	1163617.SCD_n00368	1.986e-96	319.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,2VPKX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome c-type protein	napC	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
YHH2_k127_10455490_0	1123487.KB892868_gene1265	1.595e-201	653.0	COG0515@1|root,COG0515@2|Bacteria,1QZ9Z@1224|Proteobacteria,2WIB8@28216|Betaproteobacteria,2KX7N@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YHH2_k127_10455490_4	768671.ThimaDRAFT_3465	3.027e-14	75.0	COG3514@1|root,COG3514@2|Bacteria,1N3YP@1224|Proteobacteria	1224|Proteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
YHH2_k127_10455490_1	580332.Slit_1749	1.156e-90	303.0	2E5SX@1|root,330H9@2|Bacteria,1NAZH@1224|Proteobacteria,2VW4M@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10455490_2	887062.HGR_01387	8.173e-41	151.0	COG3813@1|root,COG3813@2|Bacteria,1N712@1224|Proteobacteria,2VUUI@28216|Betaproteobacteria,4AFJC@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1272)	-	-	-	ko:K09984	-	-	-	-	ko00000	-	-	-	DUF1272
YHH2_k127_10455490_3	768671.ThimaDRAFT_3465	1.375e-36	141.0	COG3514@1|root,COG3514@2|Bacteria,1N3YP@1224|Proteobacteria	1224|Proteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
YHH2_k127_10455490_5	1158292.JPOE01000002_gene3490	2.564e-11	69.0	COG2929@1|root,COG2929@2|Bacteria,1PUH4@1224|Proteobacteria,2VX5T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_10459811_8	580332.Slit_0441	1.418e-78	264.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,44V7U@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
YHH2_k127_10459811_5	580332.Slit_0440	3.633e-93	307.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,44VQ3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_3
YHH2_k127_10459811_10	580332.Slit_0439	2.041e-58	209.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria,44VWE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
YHH2_k127_10459811_12	395494.Galf_0278	2.892e-43	165.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria,44VXS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
YHH2_k127_10459811_2	580332.Slit_0437	1.029e-132	425.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,44V0H@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
YHH2_k127_10459811_0	1485544.JQKP01000001_gene1181	1.956e-193	614.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,44UZ8@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
YHH2_k127_10459811_11	580332.Slit_0435	1.612e-54	192.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria,44W0Q@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
YHH2_k127_10459811_7	580332.Slit_0434	2.763e-81	273.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,44VUH@713636|Nitrosomonadales	28216|Betaproteobacteria	GT	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
YHH2_k127_10459811_1	580332.Slit_0433	1.259e-172	544.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,44V87@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
YHH2_k127_10459811_3	1485544.JQKP01000001_gene1177	6.715e-127	410.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,44V0U@713636|Nitrosomonadales	28216|Betaproteobacteria	S	P-loop ATPase protein family	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
YHH2_k127_10459811_9	580332.Slit_0431	2.134e-62	218.0	COG5341@1|root,COG5341@2|Bacteria,1N1PN@1224|Proteobacteria,2VUW8@28216|Betaproteobacteria,44VY7@713636|Nitrosomonadales	28216|Betaproteobacteria	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
YHH2_k127_10459811_4	580332.Slit_0430	4.204e-94	313.0	COG4769@1|root,COG4769@2|Bacteria,1RJIB@1224|Proteobacteria,2VRM1@28216|Betaproteobacteria,44VVI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
YHH2_k127_10459811_6	580332.Slit_0429	8.861e-87	287.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,44VAK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
YHH2_k127_1050837_5	580332.Slit_2040	2.397e-98	324.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,44VSH@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Nudix N-terminal	nudC_1	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
YHH2_k127_1050837_8	1454004.AW11_00552	1.425e-74	259.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,1KQ3X@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
YHH2_k127_1050837_3	580332.Slit_2038	5.955e-179	563.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,44V1W@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH2_k127_1050837_7	497321.C664_10742	2.151e-86	294.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,2KUES@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
YHH2_k127_1050837_1	580332.Slit_2105	3.717e-195	614.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,44V3M@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
YHH2_k127_1050837_9	580332.Slit_2104	6.069e-62	220.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,44VWH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
YHH2_k127_1050837_4	1296990.H845_143	8.622e-147	470.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2TUCJ@28211|Alphaproteobacteria,2JUP1@204441|Rhodospirillales	204441|Rhodospirillales	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
YHH2_k127_1050837_6	755731.Clo1100_3397	3.615e-93	308.0	COG1403@1|root,COG1403@2|Bacteria,1UUDX@1239|Firmicutes,256GS@186801|Clostridia	186801|Clostridia	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1050837_0	580332.Slit_2103	0.0	1551.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,44VM0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YHH2_k127_1050837_2	580332.Slit_2100	6.138e-181	571.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,44UZE@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH2_k127_1050837_10	580332.Slit_2099	2.308e-33	130.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2WAN7@28216|Betaproteobacteria,44W2Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
YHH2_k127_10547131_19	1331060.RLDS_11260	1.883e-17	81.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10547131_18	941449.dsx2_3012	1.924e-19	101.0	COG0535@1|root,COG0535@2|Bacteria,1RC7V@1224|Proteobacteria,42UUK@68525|delta/epsilon subdivisions,2WQ07@28221|Deltaproteobacteria,2MA7C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
YHH2_k127_10547131_10	509191.AEDB02000065_gene617	1.667e-99	335.0	COG1181@1|root,COG1181@2|Bacteria,1VEZR@1239|Firmicutes,24ITG@186801|Clostridia,3WKVS@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
YHH2_k127_10547131_16	373994.Riv7116_6668	6.936e-37	149.0	COG2720@1|root,COG2720@2|Bacteria,1G62H@1117|Cyanobacteria,1HRN9@1161|Nostocales	1117|Cyanobacteria	V	VanW like protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	VanW
YHH2_k127_10547131_13	158822.LH89_12150	1.467e-66	241.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	lysine 2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
YHH2_k127_10547131_4	395494.Galf_1347	7.282e-155	496.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,2VHCH@28216|Betaproteobacteria,44W6U@713636|Nitrosomonadales	28216|Betaproteobacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YHH2_k127_10547131_12	543728.Vapar_6081	8.905e-69	237.0	COG4731@1|root,COG4731@2|Bacteria,1N19Y@1224|Proteobacteria,2VTB1@28216|Betaproteobacteria,4ADVY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
YHH2_k127_10547131_17	663321.REG_1038	3.275e-30	124.0	COG5499@1|root,COG5499@2|Bacteria,1N89F@1224|Proteobacteria	1224|Proteobacteria	K	regulator	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
YHH2_k127_10547131_8	580332.Slit_2391	1.013e-109	356.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,2VH0C@28216|Betaproteobacteria,44VIU@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
YHH2_k127_10547131_11	580332.Slit_2392	5.331e-96	317.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,44VN8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
YHH2_k127_10547131_2	580332.Slit_2393	4.514e-216	687.0	COG4656@1|root,COG4656@2|Bacteria,1PJVF@1224|Proteobacteria,2VM4P@28216|Betaproteobacteria,44VIW@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,Fer4_8,RnfC_N,SLBB
YHH2_k127_10547131_3	580332.Slit_2394	2.718e-171	544.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,2VJZJ@28216|Betaproteobacteria,44VB4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
YHH2_k127_10547131_9	580332.Slit_2395	2.861e-100	335.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,2VS39@28216|Betaproteobacteria,44VR1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
YHH2_k127_10547131_6	580332.Slit_2396	6.507e-112	364.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2VNWT@28216|Betaproteobacteria,44UYJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
YHH2_k127_10547131_15	1485544.JQKP01000001_gene1050	3.885e-39	149.0	COG1708@1|root,COG1708@2|Bacteria,1QZYB@1224|Proteobacteria,2VW1D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH2_k127_10547131_5	580332.Slit_2397	1.106e-115	376.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2VIRB@28216|Betaproteobacteria,44VCE@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
YHH2_k127_10547131_1	580332.Slit_2565	0.0	1244.0	COG0517@1|root,COG2199@1|root,COG3829@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG3829@2|Bacteria,1RGCV@1224|Proteobacteria,2W303@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CHASE,EAL,GGDEF,MASE1,PAS,PAS_4,PAS_9,dCache_1
YHH2_k127_10547131_7	580332.Slit_2566	2.003e-110	361.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria	28216|Betaproteobacteria	K	crp fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
YHH2_k127_10547131_0	522306.CAP2UW1_2118	0.0	1518.0	COG1352@1|root,COG2201@1|root,COG3829@1|root,COG5001@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9
YHH2_k127_10580465_0	580332.Slit_1856	0.0	1490.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VHS7@28216|Betaproteobacteria,44V1M@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
YHH2_k127_10580465_4	580332.Slit_1858	2.94e-66	228.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,44WG2@713636|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM thioesterase superfamily protein	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
YHH2_k127_10580465_2	580332.Slit_1859	0.0	1011.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,44V2C@713636|Nitrosomonadales	28216|Betaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
YHH2_k127_10580465_3	580332.Slit_1860	4.997e-141	453.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,2VM6G@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
YHH2_k127_10580465_5	946483.Cenrod_2592	4.269e-29	122.0	2AII3@1|root,31901@2|Bacteria,1Q1AT@1224|Proteobacteria,2W6DW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10580465_1	580332.Slit_1861	0.0	1383.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,44VAG@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
YHH2_k127_10753331_9	580332.Slit_0509	4.076e-27	116.0	COG5126@1|root,COG5126@2|Bacteria,1PTFF@1224|Proteobacteria,2WAHF@28216|Betaproteobacteria,44WMJ@713636|Nitrosomonadales	28216|Betaproteobacteria	DTZ	SMART Calcium-binding EF-hand-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
YHH2_k127_10753331_0	580332.Slit_0508	0.0	1120.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,44VP2@713636|Nitrosomonadales	28216|Betaproteobacteria	K	RNB	rnb	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
YHH2_k127_10753331_7	580332.Slit_0507	3.233e-102	342.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,44VI1@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
YHH2_k127_10753331_12	1485544.JQKP01000010_gene847	1.279e-12	74.0	2BPQZ@1|root,32II7@2|Bacteria,1PXBH@1224|Proteobacteria,2WCT8@28216|Betaproteobacteria,44WMN@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10753331_1	395494.Galf_2088	1.451e-187	593.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria,44VAF@713636|Nitrosomonadales	28216|Betaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10753331_2	580332.Slit_0502	9.862e-153	486.0	COG0803@1|root,COG0803@2|Bacteria,1PQEX@1224|Proteobacteria,2W6SJ@28216|Betaproteobacteria,44VMA@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
YHH2_k127_10753331_6	395494.Galf_2090	7.922e-104	344.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria,44VR9@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
YHH2_k127_10753331_3	580332.Slit_0482	8.123e-148	470.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,44V22@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
YHH2_k127_10753331_4	580332.Slit_0481	1.241e-125	408.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2VHW8@28216|Betaproteobacteria,44VDB@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
YHH2_k127_10753331_8	1123487.KB892863_gene1832	7.182e-91	310.0	COG4566@1|root,COG4566@2|Bacteria,1QVXM@1224|Proteobacteria,2WGZZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH2_k127_10753331_5	1123487.KB892863_gene1831	8.941e-106	351.0	COG0642@1|root,COG2205@2|Bacteria,1QZDZ@1224|Proteobacteria,2WHKQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM
YHH2_k127_10753331_10	237368.SCABRO_02487	1.953e-25	112.0	COG3259@1|root,COG3259@2|Bacteria,2IYS2@203682|Planctomycetes	203682|Planctomycetes	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
YHH2_k127_10753331_11	469617.FUAG_01549	3.69e-14	72.0	COG1921@1|root,COG1921@2|Bacteria,37858@32066|Fusobacteria	32066|Fusobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	SelA
YHH2_k127_10757065_12	103733.JNYO01000007_gene5110	2.643e-11	64.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4E1T4@85010|Pseudonocardiales	201174|Actinobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt
YHH2_k127_10757065_11	653733.Selin_0436	2.413e-13	72.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
YHH2_k127_10757065_8	349124.Hhal_1830	7.995e-46	179.0	COG0136@1|root,335ZB@2|Bacteria,1NQEQ@1224|Proteobacteria,1SI1Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
YHH2_k127_10757065_13	94122.Shewana3_2725	8.894e-08	61.0	2C17N@1|root,32YZC@2|Bacteria,1NFDT@1224|Proteobacteria,1SEYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10757065_10	1541065.JRFE01000010_gene4323	8.123e-19	89.0	2C16Q@1|root,330H3@2|Bacteria,1G90Z@1117|Cyanobacteria,3VN20@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HicB,RHH_1
YHH2_k127_10757065_9	28072.Nos7524_2874	7.59e-44	165.0	COG1569@1|root,COG1569@2|Bacteria,1G5T4@1117|Cyanobacteria,1HQ92@1161|Nostocales	1117|Cyanobacteria	S	Toxin-antitoxin system, toxin component, PIN family	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH2_k127_10757065_0	580332.Slit_2351	2.772e-223	693.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,44VKN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YHH2_k127_10757065_6	580332.Slit_2352	9.116e-104	340.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,44VSB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
YHH2_k127_10757065_5	580332.Slit_2353	1.378e-108	356.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,44VSG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
YHH2_k127_10757065_2	580332.Slit_2354	1.221e-191	600.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,44VJC@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
YHH2_k127_10757065_14	1397696.KK211189_gene2556	3.463e-07	54.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10757065_3	580332.Slit_2355	2.761e-156	497.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,44V4C@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YHH2_k127_10757065_7	580332.Slit_2356	8.893e-87	289.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,2VUIR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
YHH2_k127_10757065_1	580332.Slit_2357	9.4e-217	689.0	COG0457@1|root,COG3071@1|root,COG0457@2|Bacteria,COG3071@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria,44VNS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
YHH2_k127_10757065_4	580332.Slit_2359	1.736e-109	359.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VJ2B@28216|Betaproteobacteria,44V3I@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YHH2_k127_10775035_5	580332.Slit_1725	8.841e-94	310.0	COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,2VTR8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
YHH2_k127_10775035_1	580332.Slit_1726	1.001e-235	732.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,44WDY@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
YHH2_k127_10775035_8	864051.BurJ1DRAFT_3321	1.028e-59	217.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,1KM2G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, luxR family	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
YHH2_k127_10775035_0	580332.Slit_1728	2.823e-275	847.0	COG0446@1|root,COG0446@2|Bacteria,1QTP3@1224|Proteobacteria,2W9DC@28216|Betaproteobacteria,44WBG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YHH2_k127_10775035_7	580332.Slit_2673	2.321e-62	219.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,44VY3@713636|Nitrosomonadales	28216|Betaproteobacteria	M	NlpC/P60 family	-	-	-	ko:K19303	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
YHH2_k127_10775035_3	580332.Slit_2674	2.064e-150	482.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,2VJGZ@28216|Betaproteobacteria,44VFF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transglycosylase SLT domain	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
YHH2_k127_10775035_2	580332.Slit_2675	6.599e-187	586.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,44VC9@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YHH2_k127_10775035_6	580332.Slit_2676	4.775e-70	241.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,44VZ1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Smr domain	smrA	-	-	-	-	-	-	-	-	-	-	-	Smr
YHH2_k127_10775035_10	580332.Slit_1653	1.424e-58	205.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,44VU5@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
YHH2_k127_10775035_9	519989.ECTPHS_06947	2.202e-59	209.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1WYAR@135613|Chromatiales	135613|Chromatiales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH2_k127_10775035_4	292415.Tbd_0706	6.088e-132	431.0	COG3746@1|root,COG3746@2|Bacteria,1QYIH@1224|Proteobacteria	1224|Proteobacteria	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
YHH2_k127_10775035_11	382464.ABSI01000012_gene2063	9.234e-35	140.0	COG4659@1|root,COG4659@2|Bacteria,46VAU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
YHH2_k127_10794247_1	1209072.ALBT01000028_gene1233	6.53e-186	594.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,1FG4K@10|Cellvibrio	1236|Gammaproteobacteria	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
YHH2_k127_10794247_3	580332.Slit_0184	8.03e-07	51.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKJI@28216|Betaproteobacteria,44VNF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH2_k127_10794247_2	748247.AZKH_0873	4.103e-44	162.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,2KWRA@206389|Rhodocyclales	206389|Rhodocyclales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YHH2_k127_10794247_0	580332.Slit_0187	0.0	997.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,44VNT@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YHH2_k127_10794247_4	1197906.CAJQ02000003_gene3219	4.263e-06	55.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JUGV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH2_k127_10802176_2	1123367.C666_14415	1.461e-60	220.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,2VIE1@28216|Betaproteobacteria,2M015@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
YHH2_k127_10802176_0	926556.Echvi_4391	4.71e-127	415.0	COG0451@1|root,COG0451@2|Bacteria,4NENI@976|Bacteroidetes	976|Bacteroidetes	M	Male sterility protein	-	-	5.1.3.26	ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
YHH2_k127_10802176_3	340177.Cag_0676	2.586e-60	218.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	tuaG	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.305	ko:K16698,ko:K21363	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
YHH2_k127_10802176_4	421531.IX38_11215	4.18e-25	117.0	arCOG09486@1|root,2ZC3Y@2|Bacteria,4NNUF@976|Bacteroidetes,1I367@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
YHH2_k127_10802176_1	857087.Metme_2931	1.229e-78	267.0	COG0438@1|root,COG0438@2|Bacteria,1RF4D@1224|Proteobacteria	1224|Proteobacteria	M	TIGRFAM methyltransferase FkbM	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
YHH2_k127_10807948_4	883126.HMPREF9710_00495	1.855e-96	326.0	COG2378@1|root,COG2378@2|Bacteria,1QYA2@1224|Proteobacteria,2VMMT@28216|Betaproteobacteria,47879@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
YHH2_k127_10807948_5	1458357.BG58_03920	1.027e-06	55.0	2DQNA@1|root,337RM@2|Bacteria,1PWC8@1224|Proteobacteria,2WBX5@28216|Betaproteobacteria,1KB0N@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10807948_0	748247.AZKH_1140	3.749e-196	623.0	COG2251@1|root,COG2251@2|Bacteria,1QUUG@1224|Proteobacteria,2W0DD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
YHH2_k127_10807948_2	580332.Slit_0511	1.519e-143	457.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria,44VFD@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
YHH2_k127_10807948_3	580332.Slit_0512	5.977e-100	327.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,44VRQ@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
YHH2_k127_10807948_1	580332.Slit_0513	5.325e-166	532.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,2VJX1@28216|Betaproteobacteria,44VIP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	UbiA prenyltransferase family	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
YHH2_k127_10814927_1	580332.Slit_1259	3.833e-135	438.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,44WDQ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
YHH2_k127_10814927_0	580332.Slit_1260	2.42e-154	490.0	COG2518@1|root,COG2518@2|Bacteria,1NMMQ@1224|Proteobacteria,2VH3B@28216|Betaproteobacteria,44VBR@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
YHH2_k127_10814927_2	580332.Slit_1261	9.056e-57	200.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2VSUJ@28216|Betaproteobacteria,44VWR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
YHH2_k127_10814927_3	1454004.AW11_01193	7.046e-37	156.0	COG1864@1|root,COG2931@1|root,COG3179@1|root,COG3209@1|root,COG3391@1|root,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3179@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,1RC1P@1224|Proteobacteria,2VUZC@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19
YHH2_k127_10914734_3	1123487.KB892835_gene3673	6.721e-119	394.0	COG3550@1|root,COG3550@2|Bacteria,1MW9U@1224|Proteobacteria,2VSWQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
YHH2_k127_10914734_5	580332.Slit_0473	8.192e-45	164.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,2VVS3@28216|Betaproteobacteria,44W1B@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Frataxin-like domain	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
YHH2_k127_10914734_2	580332.Slit_0474	7.645e-136	447.0	COG1965@1|root,COG3577@1|root,COG1965@2|Bacteria,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	cyaY	GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564	1.16.3.1	ko:K06202,ko:K06985,ko:K19054	ko00860,ko04112,map00860,map04112	-	R00078	RC02758	ko00000,ko00001,ko01000,ko03029	-	-	iECW_1372.ECW_m4108,iEKO11_1354.EKO11_4552,iWFL_1372.ECW_m4108	Frataxin_Cyay,gag-asp_proteas
YHH2_k127_10914734_1	580332.Slit_0475	3.21e-231	725.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,44VK2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YHH2_k127_10914734_4	1485544.JQKP01000001_gene1164	1.875e-106	357.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18306	ko02024,map02024	M00644	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2.20,2.A.6.2.32,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH2_k127_10914734_0	1485544.JQKP01000001_gene1165	0.0	1212.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44VNU@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD4	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YHH2_k127_10927471_21	643867.Ftrac_1703	1.125e-48	177.0	28W66@1|root,2ZI6U@2|Bacteria,4P8V7@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10927471_14	358220.C380_18700	1.147e-82	280.0	COG0745@1|root,COG0745@2|Bacteria,1R7R1@1224|Proteobacteria,2VQPB@28216|Betaproteobacteria,4AI65@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07666,ko:K07771	ko01503,ko02020,ko02024,map01503,map02020,map02024	M00451,M00453,M00721,M00722	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_10927471_19	358220.C380_18705	5.024e-66	246.0	COG0642@1|root,COG2205@2|Bacteria,1PFFB@1224|Proteobacteria,2W941@28216|Betaproteobacteria,4AHTR@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
YHH2_k127_10927471_28	1123228.AUIH01000001_gene1405	8.682e-26	116.0	2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria,1XM11@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF2799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2799
YHH2_k127_10927471_2	580332.Slit_2125	1.504e-268	830.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,44V0G@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
YHH2_k127_10927471_12	580332.Slit_2123	2.762e-128	411.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,44V73@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
YHH2_k127_10927471_31	518766.Rmar_1467	1.491e-18	88.0	COG1708@1|root,COG1708@2|Bacteria,4NUTI@976|Bacteroidetes	976|Bacteroidetes	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH2_k127_10927471_33	555778.Hneap_0234	1.098e-06	57.0	2C4WJ@1|root,32Z4K@2|Bacteria,1MZU5@1224|Proteobacteria,1S6A8@1236|Gammaproteobacteria,1X0VW@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10927471_7	580332.Slit_2122	4.607e-221	686.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,44VCP@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH2_k127_10927471_5	580332.Slit_2121	3.61e-222	690.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria,44W4D@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YHH2_k127_10927471_8	580332.Slit_2120	6.588e-211	688.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,44VR7@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
YHH2_k127_10927471_16	580332.Slit_2119	2.823e-82	278.0	COG0619@1|root,COG0619@2|Bacteria,1N7EI@1224|Proteobacteria,2VWJT@28216|Betaproteobacteria,44VYV@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	-	-	-	-	-	-	-	-	-	CbiQ
YHH2_k127_10927471_11	580332.Slit_2118	1.866e-148	473.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,44V8K@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
YHH2_k127_10927471_13	1485544.JQKP01000005_gene356	1.336e-93	315.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,44VEB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
YHH2_k127_10927471_3	580332.Slit_2115	1.877e-254	788.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,44V9J@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH2_k127_10927471_27	1122222.AXWR01000023_gene1538	1.387e-26	113.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_10927471_25	880072.Desac_2954	5.224e-30	119.0	COG1598@1|root,COG1598@2|Bacteria,1NCC0@1224|Proteobacteria,42UMY@68525|delta/epsilon subdivisions,2WQUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
YHH2_k127_10927471_10	580332.Slit_2114	7.176e-157	496.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,44UZC@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
YHH2_k127_10927471_9	580332.Slit_2113	6.588e-171	539.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria,44VH8@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YHH2_k127_10927471_4	580332.Slit_2111	2.299e-245	764.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,44V34@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Mur ligase middle domain protein	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH2_k127_10927471_18	580332.Slit_2110	8.578e-68	236.0	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,44VYQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sporulation related domain	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
YHH2_k127_10927471_17	580332.Slit_2109	5.428e-68	237.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2VUM6@28216|Betaproteobacteria,44W0T@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
YHH2_k127_10927471_0	580332.Slit_2108	4.649e-310	954.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,44VHT@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
YHH2_k127_10927471_23	631362.Thi970DRAFT_00394	7.764e-46	167.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,1X134@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
YHH2_k127_10927471_26	443143.GM18_0943	3.845e-27	112.0	COG1396@1|root,COG1396@2|Bacteria,1NE0Y@1224|Proteobacteria,431D0@68525|delta/epsilon subdivisions,2WWHM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH2_k127_10927471_6	580332.Slit_2107	5.397e-222	692.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,44VB6@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
YHH2_k127_10927471_20	1485544.JQKP01000005_gene366	4.253e-65	226.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria,44VUA@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
YHH2_k127_10927471_1	580332.Slit_2036	1.081e-274	852.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VHKK@28216|Betaproteobacteria,44VMM@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
YHH2_k127_10927471_24	1095769.CAHF01000005_gene1464	3.004e-40	158.0	2EDK5@1|root,337FY@2|Bacteria,1ND05@1224|Proteobacteria,2W4RU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10927471_15	580332.Slit_2802	2.17e-82	277.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2VUBT@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
YHH2_k127_10927471_30	580332.Slit_2093	6.016e-19	86.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,44V5K@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YHH2_k127_10927471_22	587753.EY04_04255	6.624e-48	177.0	COG0454@1|root,COG0456@2|Bacteria,1RI07@1224|Proteobacteria,1S7S4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
YHH2_k127_10927471_29	1187851.A33M_0781	1.477e-24	107.0	COG5652@1|root,COG5652@2|Bacteria,1RDK4@1224|Proteobacteria,2U7BI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10928523_9	431947.PGN_0590	2.134e-100	336.0	COG1522@1|root,COG3177@1|root,COG1522@2|Bacteria,COG3177@2|Bacteria,4NHPW@976|Bacteroidetes,2FQXS@200643|Bacteroidia,22YA0@171551|Porphyromonadaceae	976|Bacteroidetes	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
YHH2_k127_10928523_19	317025.Tcr_2118	1.81e-08	55.0	2EHR8@1|root,33BH1@2|Bacteria,1NC7E@1224|Proteobacteria,1SRBR@1236|Gammaproteobacteria,462W6@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10928523_21	69042.WH5701_04165	1.186e-07	53.0	COG0286@1|root,COG0286@2|Bacteria,1G0GY@1117|Cyanobacteria,1GZ79@1129|Synechococcus	1117|Cyanobacteria	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
YHH2_k127_10928523_16	1298920.KI911353_gene4531	3.845e-31	130.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,249TP@186801|Clostridia,223VS@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
YHH2_k127_10928523_14	640081.Dsui_1482	2.667e-41	153.0	COG4680@1|root,COG4680@2|Bacteria,1N036@1224|Proteobacteria,2VSXP@28216|Betaproteobacteria,2KZGE@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
YHH2_k127_10928523_6	640081.Dsui_1483	6.271e-164	525.0	COG2856@1|root,COG5499@1|root,COG2856@2|Bacteria,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,2VRK1@28216|Betaproteobacteria,2KXA3@206389|Rhodocyclales	206389|Rhodocyclales	K	regulator	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
YHH2_k127_10928523_18	118005.AWNK01000006_gene1412	7.684e-14	73.0	COG4804@1|root,COG4804@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
YHH2_k127_10928523_10	94122.Shewana3_3623	6.038e-91	309.0	2DBUY@1|root,2ZB8R@2|Bacteria,1R9MD@1224|Proteobacteria,1T7PI@1236|Gammaproteobacteria,2QDB8@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
YHH2_k127_10928523_1	580332.Slit_1127	4e-323	995.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria	28216|Betaproteobacteria	P	von Willebrand factor, type A	norD	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
YHH2_k127_10928523_4	580332.Slit_1126	1.049e-188	591.0	COG0348@1|root,COG0348@2|Bacteria,1MUWD@1224|Proteobacteria,2VMUP@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
YHH2_k127_10928523_7	1163617.SCD_n00454	1.801e-155	492.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_5	norQ	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
YHH2_k127_10928523_2	580332.Slit_1122	4.152e-278	857.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,2VHXU@28216|Betaproteobacteria,44WAP@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c oxidase subunit I	norB	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
YHH2_k127_10928523_11	580332.Slit_1121	4.164e-83	278.0	COG2010@1|root,COG2010@2|Bacteria,1RG22@1224|Proteobacteria,2W8VP@28216|Betaproteobacteria,44WMU@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c class I	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
YHH2_k127_10928523_5	580332.Slit_1119	2.212e-181	576.0	COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,2VNAW@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10928523_17	580332.Slit_1118	3.519e-22	97.0	COG0425@1|root,COG0425@2|Bacteria,1QU8C@1224|Proteobacteria,2WGIR@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
YHH2_k127_10928523_13	580332.Slit_1117	1.972e-54	194.0	COG3945@1|root,COG3945@2|Bacteria,1N383@1224|Proteobacteria,2VUXI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YHH2_k127_10928523_8	580332.Slit_1116	6.028e-113	369.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria	28216|Betaproteobacteria	K	CRP FNR family	dnrD	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YHH2_k127_10928523_20	1121890.AUDO01000001_gene579	1.996e-08	57.0	COG3177@1|root,COG3177@2|Bacteria,4NF0H@976|Bacteroidetes,1HZFZ@117743|Flavobacteriia,2NU3W@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
YHH2_k127_10928523_3	1163617.SCD_n01692	1.207e-215	674.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2VM95@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
YHH2_k127_10928523_0	243233.MCA2543	0.0	1797.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1XE1A@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
YHH2_k127_10928523_12	398511.BpOF4_21324	3.511e-64	235.0	2DRN6@1|root,33CCH@2|Bacteria	2|Bacteria	S	Protein of unknown function (Hypoth_ymh)	-	-	-	-	-	-	-	-	-	-	-	-	Hypoth_Ymh
YHH2_k127_10928523_15	1522072.IL54_3527	1.148e-35	140.0	2CGQH@1|root,32S4D@2|Bacteria,1N40M@1224|Proteobacteria,2UAPU@28211|Alphaproteobacteria,2K7JP@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH2_k127_10936846_3	580332.Slit_1452	3.625e-212	665.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria,44VEC@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
YHH2_k127_10936846_4	580332.Slit_1450	1.782e-206	645.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,2VPZ0@28216|Betaproteobacteria,44W77@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
YHH2_k127_10936846_0	631362.Thi970DRAFT_03464	0.0	1169.0	COG0642@1|root,COG0834@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1X2RK@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,MASE1,PAS_9,Response_reg
YHH2_k127_10936846_1	395495.Lcho_3702	3.064e-230	740.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KJEE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
YHH2_k127_10936846_8	1121396.KB892945_gene2890	3.314e-27	115.0	2BK43@1|root,32EHP@2|Bacteria,1RDAC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10936846_7	1460640.JCM19046_3053	4.248e-35	137.0	2DNKZ@1|root,32Y1N@2|Bacteria,1TYVC@1239|Firmicutes,4I80Y@91061|Bacilli,1ZIDE@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2750)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2750
YHH2_k127_10936846_2	322710.Avin_24740	2.485e-221	699.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
YHH2_k127_10936846_9	322710.Avin_24740	3.542e-09	58.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
YHH2_k127_10936846_5	580332.Slit_2418	3.745e-133	428.0	COG2042@1|root,COG3376@2|Bacteria,1MUYH@1224|Proteobacteria,2VJDC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	hoxN	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
YHH2_k127_10936846_6	261292.Nit79A3_3382	8.083e-105	355.0	COG0784@1|root,COG2200@1|root,COG0784@2|Bacteria,COG2200@2|Bacteria,1NC9X@1224|Proteobacteria,2WGSU@28216|Betaproteobacteria,374RA@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Response_reg
YHH2_k127_10954879_6	580332.Slit_2223	1.386e-14	74.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,44WEH@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
YHH2_k127_10954879_2	395494.Galf_1826	7.626e-82	273.0	COG0720@1|root,COG0720@2|Bacteria,1RETG@1224|Proteobacteria,2VRBN@28216|Betaproteobacteria,44VRF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
YHH2_k127_10954879_0	395494.Galf_1827	1.311e-204	642.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VJD3@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
YHH2_k127_10954879_5	314225.ELI_08225	4.707e-26	123.0	COG1475@1|root,COG1475@2|Bacteria,1P0WH@1224|Proteobacteria,2UUJW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10954879_1	925775.XVE_4107	8.089e-100	335.0	COG0338@1|root,COG0338@2|Bacteria,1NTIK@1224|Proteobacteria,1RSG6@1236|Gammaproteobacteria,1XA7Q@135614|Xanthomonadales	135614|Xanthomonadales	L	PFAM D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
YHH2_k127_10954879_3	202955.BBND01000034_gene1890	1.136e-39	149.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,1S6BG@1236|Gammaproteobacteria,3NNJM@468|Moraxellaceae	1236|Gammaproteobacteria	S	RelE toxin of RelE / RelB toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
YHH2_k127_10954879_4	555779.Dthio_PD0017	6.074e-27	112.0	COG2944@1|root,COG2944@2|Bacteria,1MZGM@1224|Proteobacteria,43B8F@68525|delta/epsilon subdivisions,2X6MT@28221|Deltaproteobacteria,2MH4P@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
YHH2_k127_10979097_8	1331060.RLDS_11260	1.407e-20	91.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10979097_9	1458275.AZ34_09565	2.65e-20	93.0	2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria,2VX4M@28216|Betaproteobacteria,4AFZR@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
YHH2_k127_10979097_1	580332.Slit_1565	6.082e-127	409.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,2VHQA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH2_k127_10979097_0	522306.CAP2UW1_2942	3.477e-141	454.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,2VHZ1@28216|Betaproteobacteria,1KQM2@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
YHH2_k127_10979097_2	1046627.BZARG_3068	1.195e-115	388.0	COG3943@1|root,COG3943@2|Bacteria,4NEGN@976|Bacteroidetes,1HYIM@117743|Flavobacteriia	976|Bacteroidetes	S	Toxin-antitoxin system, toxin component, Fic family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
YHH2_k127_10979097_6	395494.Galf_1300	1.046e-36	138.0	COG3657@1|root,COG3657@2|Bacteria,1N4W9@1224|Proteobacteria,2VUJF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	addiction module killer protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10979097_10	395494.Galf_1300	4.122e-19	87.0	COG3657@1|root,COG3657@2|Bacteria,1N4W9@1224|Proteobacteria,2VUJF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	addiction module killer protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10979097_4	395494.Galf_1299	2.563e-52	188.0	COG3636@1|root,COG3636@2|Bacteria,1N0RK@1224|Proteobacteria,2VTIU@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10979097_5	580332.Slit_1549	2.548e-51	183.0	COG5499@1|root,COG5499@2|Bacteria,1N89F@1224|Proteobacteria,2VWB3@28216|Betaproteobacteria,44WNE@713636|Nitrosomonadales	28216|Betaproteobacteria	K	SMART helix-turn-helix domain protein	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
YHH2_k127_10979097_3	1410619.SRDD_08440	5.675e-107	357.0	28P53@1|root,2ZC07@2|Bacteria,1RAD6@1224|Proteobacteria,1SHD8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10979097_7	1410619.SRDD_08430	1.276e-34	140.0	2EAV9@1|root,334WR@2|Bacteria,1P4U3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10991121_1	1288963.ADIS_2059	1.924e-98	326.0	COG0270@1|root,COG0789@1|root,COG0270@2|Bacteria,COG0789@2|Bacteria,4NG9A@976|Bacteroidetes,47XI8@768503|Cytophagia	976|Bacteroidetes	H	PFAM C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_17,MerR,MerR_1
YHH2_k127_10991121_4	228405.HNE_2543	1.297e-17	84.0	COG1813@1|root,COG1813@2|Bacteria,1NANQ@1224|Proteobacteria,2TXAN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH2_k127_10991121_3	118173.KB235914_gene3028	3.13e-22	99.0	28IYQ@1|root,2Z8WB@2|Bacteria	2|Bacteria	S	Type II restriction endonuclease EcoO109I	-	-	-	-	-	-	-	-	-	-	-	-	RE_EcoO109I
YHH2_k127_10991121_0	1000565.METUNv1_02811	1.792e-138	464.0	COG4585@1|root,COG4585@2|Bacteria,1R1TC@1224|Proteobacteria,2VHUA@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA_3
YHH2_k127_11047006_1	1485544.JQKP01000017_gene638	1.158e-42	160.0	COG2703@1|root,COG2703@2|Bacteria,1N9YV@1224|Proteobacteria	1224|Proteobacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
YHH2_k127_11047006_0	580332.Slit_2154	8.872e-146	465.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria,44W4Y@713636|Nitrosomonadales	28216|Betaproteobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
YHH2_k127_1107233_0	580332.Slit_0982	4.529e-278	861.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,44VCR@713636|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter transmembrane region	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH2_k127_1107412_5	580332.Slit_0524	2.073e-67	229.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,44V5Y@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
YHH2_k127_1107412_11	153948.NAL212_2545	1.351e-24	104.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VHG5@28216|Betaproteobacteria,371Q8@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	intB	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
YHH2_k127_1107412_14	1169143.KB911036_gene4711	2.147e-06	59.0	2A84U@1|root,30X5K@2|Bacteria,1PIZD@1224|Proteobacteria,2W7JD@28216|Betaproteobacteria,1KEQ0@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1107412_10	153948.NAL212_2543	1.15e-24	105.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	ko:K07733	-	-	-	-	ko00000,ko03000	-	-	-	Phage_AlpA
YHH2_k127_1107412_12	153948.NAL212_1965	7.392e-18	88.0	2DR34@1|root,339YW@2|Bacteria,1NMQA@1224|Proteobacteria,2VY5F@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_39
YHH2_k127_1107412_8	1218075.BAYA01000006_gene2439	2.347e-34	134.0	COG3093@1|root,COG3093@2|Bacteria,1N2BD@1224|Proteobacteria,2VVV1@28216|Betaproteobacteria,1K8GJ@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
YHH2_k127_1107412_7	153948.NAL212_1969	1.523e-46	169.0	COG3514@1|root,COG3514@2|Bacteria,1N7UF@1224|Proteobacteria,2VW3X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
YHH2_k127_1107412_9	153948.NAL212_1970	4.825e-25	106.0	COG2929@1|root,COG2929@2|Bacteria,1N83Z@1224|Proteobacteria,2VVVC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_1107412_6	338969.Rfer_0745	4.354e-53	193.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,4AES2@80864|Comamonadaceae	28216|Betaproteobacteria	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
YHH2_k127_1107412_4	580332.Slit_1013	1.035e-107	352.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria,44WDR@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_1107412_2	580332.Slit_1012	2.198e-159	514.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,44W7J@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	qseC	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
YHH2_k127_1107412_1	580332.Slit_0525	3.655e-223	699.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1PPH1@1224|Proteobacteria,2W9GU@28216|Betaproteobacteria,44WKA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
YHH2_k127_1107412_3	580332.Slit_0870	3.166e-131	425.0	2DYMX@1|root,34AD8@2|Bacteria,1R128@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1107412_0	580332.Slit_1447	5.38e-267	832.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2WHYC@28216|Betaproteobacteria,44WNC@713636|Nitrosomonadales	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
YHH2_k127_11098624_4	580332.Slit_0344	2.252e-25	107.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2WHEI@28216|Betaproteobacteria,44UZ2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH2_k127_11098624_3	580332.Slit_0345	2.825e-33	129.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2VW5V@28216|Betaproteobacteria,44W17@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
YHH2_k127_11098624_2	580332.Slit_0346	4.225e-67	231.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,44VWI@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
YHH2_k127_11098624_1	395494.Galf_0205	3.614e-75	258.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,44VQ7@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
YHH2_k127_11098624_0	580332.Slit_0348	4.219e-184	581.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,44VK7@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YHH2_k127_11099806_4	1485544.JQKP01000004_gene563	4.194e-15	79.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria,44WD2@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Carbohydrate phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
YHH2_k127_11099806_0	580332.Slit_0327	3.555e-140	452.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,2VK7Z@28216|Betaproteobacteria,44VI2@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YHH2_k127_11099806_3	349521.HCH_04642	1.994e-41	177.0	COG0457@1|root,COG3712@1|root,COG4773@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,COG4773@2|Bacteria,1RJUD@1224|Proteobacteria,1S0ET@1236|Gammaproteobacteria	1236|Gammaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TonB_dep_Rec
YHH2_k127_11099806_2	1000565.METUNv1_02488	3.1e-47	181.0	COG2984@1|root,COG2984@2|Bacteria,1NACH@1224|Proteobacteria,2VSU8@28216|Betaproteobacteria,2KWT6@206389|Rhodocyclales	206389|Rhodocyclales	S	transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
YHH2_k127_11099806_1	62928.azo3438	1.348e-133	449.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,2KUH6@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
YHH2_k127_11100367_4	1163617.SCD_n01736	1.804e-192	603.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
YHH2_k127_11100367_2	580332.Slit_1265	4.308e-287	889.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,44V5X@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
YHH2_k127_11100367_15	580332.Slit_1266	8.569e-55	193.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,44VXA@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
YHH2_k127_11100367_12	580332.Slit_1267	1.528e-111	361.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,44VGC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
YHH2_k127_11100367_6	580332.Slit_1268	1.975e-150	479.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria,44V60@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH2_k127_11100367_10	580332.Slit_1269	6.685e-118	391.0	COG2114@1|root,COG2114@2|Bacteria,1RD0X@1224|Proteobacteria,2VS0D@28216|Betaproteobacteria,44VWF@713636|Nitrosomonadales	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,PEGA
YHH2_k127_11100367_18	580332.Slit_1270	7.783e-32	128.0	COG3063@1|root,COG3063@2|Bacteria,1N7DT@1224|Proteobacteria,2VW37@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11100367_5	580332.Slit_1271	7.222e-164	524.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
YHH2_k127_11100367_1	580332.Slit_1273	4.932e-292	901.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2VHA7@28216|Betaproteobacteria,44VJB@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH2_k127_11100367_11	580332.Slit_1274	2.368e-114	370.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,44V7B@713636|Nitrosomonadales	28216|Betaproteobacteria	K	TIGRFAM RNA polymerase sigma factor RpoE	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_11100367_13	580332.Slit_1275	7.634e-74	252.0	COG3073@1|root,COG3073@2|Bacteria,1QANZ@1224|Proteobacteria,2VVPR@28216|Betaproteobacteria,44VXX@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM Anti sigma-E protein RseA family protein	rseA	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
YHH2_k127_11100367_8	580332.Slit_1276	1.156e-121	402.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,44V1A@713636|Nitrosomonadales	28216|Betaproteobacteria	T	MucB/RseB C-terminal domain	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
YHH2_k127_11100367_16	580332.Slit_1277	8.883e-47	172.0	COG3086@1|root,COG3086@2|Bacteria,1PVB3@1224|Proteobacteria,2VYDY@28216|Betaproteobacteria,44W2T@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM Positive regulator of sigma(E) RseC MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
YHH2_k127_11100367_3	580332.Slit_1278	2.736e-225	709.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,44VH5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S1 and S6 chymotrypsin Hap	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH2_k127_11100367_0	580332.Slit_1279	0.0	1122.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,44V33@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YHH2_k127_11100367_7	580332.Slit_1280	8.986e-143	456.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,44VE2@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Peptidase S24 S26A S26B, conserved region	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YHH2_k127_11100367_19	580332.Slit_1281	1.626e-23	104.0	29X95@1|root,30IYK@2|Bacteria,1Q9AG@1224|Proteobacteria,2WCGR@28216|Betaproteobacteria,44W1V@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
YHH2_k127_11100367_9	580332.Slit_1282	6.508e-120	387.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,44VQ8@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YHH2_k127_11100367_14	395494.Galf_1193	6.559e-71	244.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,44VDI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
YHH2_k127_11203813_1	580332.Slit_1881	1.057e-62	217.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,44VG6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DEAD DEAH box helicase domain protein	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
YHH2_k127_11203813_0	580332.Slit_1594	7.571e-251	813.0	COG2202@1|root,COG2203@1|root,COG2972@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2972@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2WEET@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,dCache_1
YHH2_k127_11260397_2	580332.Slit_1460	1.07e-191	634.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W78@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS,PAS_9,dCache_2
YHH2_k127_11260397_0	580332.Slit_1305	0.0	1527.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,44VIM@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH2_k127_11260397_1	580332.Slit_1404	6.279e-245	766.0	COG0664@1|root,COG0668@1|root,COG0664@2|Bacteria,COG0668@2|Bacteria,1R6J6@1224|Proteobacteria,2VPCU@28216|Betaproteobacteria,44W84@713636|Nitrosomonadales	28216|Betaproteobacteria	MT	MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
YHH2_k127_11260397_3	580332.Slit_1403	4.701e-67	232.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,2WGEF@28216|Betaproteobacteria,44VSA@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PhosphMutase
YHH2_k127_1140038_1	580332.Slit_1502	1.357e-208	655.0	2CG46@1|root,2Z7W3@2|Bacteria,1NFW3@1224|Proteobacteria,2VN3X@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1140038_3	84531.JMTZ01000060_gene2488	2.532e-55	202.0	28KTK@1|root,2ZAAP@2|Bacteria,1RCI8@1224|Proteobacteria,1SN8Z@1236|Gammaproteobacteria,1X5XW@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1140038_0	580332.Slit_1500	0.0	1384.0	COG1196@1|root,COG1196@2|Bacteria,1NGZ2@1224|Proteobacteria,2VIWY@28216|Betaproteobacteria	28216|Betaproteobacteria	D	SMC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_29,SMC_N
YHH2_k127_1140038_2	1123367.C666_11925	4.677e-74	262.0	2DZNC@1|root,32VEI@2|Bacteria,1N426@1224|Proteobacteria,2VVJB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function C-terminus (DUF2399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399
YHH2_k127_1140038_4	1331060.RLDS_11260	5.574e-18	83.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1140449_5	1331060.RLDS_11260	5.574e-18	83.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1140449_3	1132855.KB913035_gene819	2.366e-37	143.0	COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,2VUSH@28216|Betaproteobacteria,2KP2U@206350|Nitrosomonadales	206350|Nitrosomonadales	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	-	-	-	-	-	-	-	-	-	HigB-like_toxin
YHH2_k127_1140449_2	1218075.BAYA01000006_gene2439	1.9e-38	145.0	COG3093@1|root,COG3093@2|Bacteria,1N2BD@1224|Proteobacteria,2VVV1@28216|Betaproteobacteria,1K8GJ@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
YHH2_k127_1140449_1	452637.Oter_1057	1.384e-39	162.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	bspA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K05802,ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.1.2,1.A.23.1.3	-	-	MS_channel,MscS_TM,MscS_porin,Pkinase
YHH2_k127_1140449_0	1390370.O203_21305	4.916e-110	368.0	COG0464@1|root,COG0464@2|Bacteria,1MVVP@1224|Proteobacteria,1RY8X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0464 ATPases of the AAA class	-	-	-	-	-	-	-	-	-	-	-	-	AAA
YHH2_k127_1140449_4	375286.mma_1739	1.156e-20	98.0	COG1404@1|root,COG1404@2|Bacteria,1MVE6@1224|Proteobacteria,2W9YM@28216|Betaproteobacteria,475HI@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH2_k127_11406119_0	580332.Slit_0739	3.239e-183	575.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,44V3P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
YHH2_k127_11406119_3	580332.Slit_0699	5.669e-25	104.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,44W27@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
YHH2_k127_11406119_1	580332.Slit_0698	1.218e-41	158.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2VU1B@28216|Betaproteobacteria,44W1P@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
YHH2_k127_11406119_7	998674.ATTE01000001_gene1167	1.876e-07	62.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_11406119_2	1541065.JRFE01000068_gene2703	2.52e-36	142.0	COG1487@1|root,COG1487@2|Bacteria,1G6K5@1117|Cyanobacteria	1117|Cyanobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH2_k127_11406119_5	1132836.RCCGE510_10839	2.763e-11	75.0	2BW8H@1|root,32QZ9@2|Bacteria,1P2B4@1224|Proteobacteria,2UV3N@28211|Alphaproteobacteria,4BFHV@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11406119_4	1331060.RLDS_11260	5.574e-18	83.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1140962_11	1331060.RLDS_11260	5.574e-18	83.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1140962_8	395494.Galf_0383	4.399e-94	317.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2W96D@28216|Betaproteobacteria,44WDI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
YHH2_k127_1140962_10	1123401.JHYQ01000014_gene811	3.789e-54	192.0	COG0727@1|root,COG0727@2|Bacteria,1RGTX@1224|Proteobacteria,1S6FY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
YHH2_k127_1140962_9	395494.Galf_1244	5.033e-89	302.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria,44V2F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Spermine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
YHH2_k127_1140962_7	580332.Slit_2559	3.234e-97	320.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2VP8A@28216|Betaproteobacteria,44W9X@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	hyfI	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
YHH2_k127_1140962_0	580332.Slit_2560	1.569e-301	928.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2VJ0R@28216|Betaproteobacteria,44W90@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 30 kDa subunit	hyfG	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
YHH2_k127_1140962_1	580332.Slit_2561	5.871e-290	893.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria,44W60@713636|Nitrosomonadales	28216|Betaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	hyfF	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
YHH2_k127_1140962_12	1485544.JQKP01000001_gene1003	0.0002294	44.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,2VJNA@28216|Betaproteobacteria,44W97@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifN	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
YHH2_k127_1140962_4	580332.Slit_2562	7.121e-113	367.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2VJTI@28216|Betaproteobacteria,44W5S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	hydrogenase 4 membrane	hyfE	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
YHH2_k127_1140962_3	580332.Slit_2563	4.425e-169	536.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2VKBD@28216|Betaproteobacteria,44W66@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NADH dehydrogenase	hyfD	-	-	-	-	-	-	-	-	-	-	-	NADHdh
YHH2_k127_1140962_2	32057.KB217472_gene7933	2.779e-202	644.0	COG2159@1|root,COG2159@2|Bacteria,1G4UT@1117|Cyanobacteria,1HR4A@1161|Nostocales	1117|Cyanobacteria	S	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
YHH2_k127_1140962_5	1270196.JCKI01000010_gene818	2.096e-112	369.0	COG3617@1|root,COG3617@2|Bacteria,4NIG0@976|Bacteroidetes	976|Bacteroidetes	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
YHH2_k127_1140962_6	580332.Slit_2564	9.354e-103	336.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,2VMAN@28216|Betaproteobacteria,44WCY@713636|Nitrosomonadales	28216|Betaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	hyfB	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
YHH2_k127_11414081_4	1101195.Meth11DRAFT_1633	2.064e-120	391.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,2VM49@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
YHH2_k127_11414081_6	1116472.MGMO_154c00070	3.147e-110	368.0	COG4783@1|root,COG4783@2|Bacteria,1QV70@1224|Proteobacteria,1T5BQ@1236|Gammaproteobacteria,1XGPM@135618|Methylococcales	135618|Methylococcales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH2_k127_11414081_1	580332.Slit_1252	7.042e-188	595.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VK6G@28216|Betaproteobacteria,44VCQ@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
YHH2_k127_11414081_8	62928.azo3097	1.663e-05	48.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,2KUMB@206389|Rhodocyclales	206389|Rhodocyclales	P	Von Willebrand factor type A	norD	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA
YHH2_k127_11414081_2	580332.Slit_1755	1e-179	567.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,2VJ71@28216|Betaproteobacteria,44VBJ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	FtsJ-like methyltransferase	rlmM	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
YHH2_k127_11414081_7	1121035.AUCH01000001_gene1772	1.73e-57	206.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2VR9D@28216|Betaproteobacteria,2M021@206389|Rhodocyclales	206389|Rhodocyclales	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
YHH2_k127_11414081_5	580332.Slit_1754	7.333e-115	374.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,44UYP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH2_k127_11414081_3	580332.Slit_1753	1.178e-167	531.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,44V82@713636|Nitrosomonadales	28216|Betaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
YHH2_k127_11414081_0	580332.Slit_1752	1.626e-188	594.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
YHH2_k127_11467277_3	395494.Galf_1808	5.573e-171	544.0	COG1879@1|root,COG1879@2|Bacteria,1MXQN@1224|Proteobacteria,2VS1W@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Periplasmic binding protein LacI transcriptional regulator	torT	-	-	ko:K11930	-	-	-	-	ko00000	-	-	-	Peripla_BP_1,Peripla_BP_4
YHH2_k127_11467277_7	395494.Galf_1806	1.218e-91	334.0	COG2199@1|root,COG3850@1|root,COG2199@2|Bacteria,COG3850@2|Bacteria,1RGCV@1224|Proteobacteria,2WGZP@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3
YHH2_k127_11467277_6	365044.Pnap_2688	4.225e-126	437.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,4ADJN@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_11467277_9	580332.Slit_2346	1.09e-57	203.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,2VTZE@28216|Betaproteobacteria,44VZG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0225 family	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
YHH2_k127_11467277_2	580332.Slit_2348	2.551e-205	640.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,44V37@713636|Nitrosomonadales	28216|Betaproteobacteria	H	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
YHH2_k127_11467277_0	580332.Slit_2519	6.455e-259	805.0	COG0260@1|root,COG0260@2|Bacteria,1MXP6@1224|Proteobacteria,2VJ0K@28216|Betaproteobacteria,44UZA@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM peptidase M17 leucyl aminopeptidase domain protein	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
YHH2_k127_11467277_10	1120999.JONM01000024_gene3082	9.482e-37	143.0	COG3744@1|root,COG3744@2|Bacteria,1N2T0@1224|Proteobacteria,2VTSR@28216|Betaproteobacteria,2KS2C@206351|Neisseriales	206351|Neisseriales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_11467277_11	264198.Reut_C6345	1.193e-28	116.0	COG4118@1|root,COG4118@2|Bacteria,1N7BG@1224|Proteobacteria,2VY0B@28216|Betaproteobacteria,1K9M1@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_11467277_5	580332.Slit_2520	3.448e-162	512.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,44VCH@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
YHH2_k127_11467277_12	870187.Thini_3620	0.0001846	44.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,461TY@72273|Thiotrichales	72273|Thiotrichales	L	ATP-dependent helicase HrpB	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
YHH2_k127_11467277_4	396588.Tgr7_3178	8.061e-164	536.0	COG0469@1|root,COG0469@2|Bacteria,1NNNX@1224|Proteobacteria,1RYF5@1236|Gammaproteobacteria,1X04N@135613|Chromatiales	135613|Chromatiales	G	PFAM Pyruvate kinase barrel	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
YHH2_k127_11467277_8	580332.Slit_2522	1.073e-77	263.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria,44VR3@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
YHH2_k127_11467277_1	580332.Slit_2532	6.46e-245	762.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VHHU@28216|Betaproteobacteria,44V28@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
YHH2_k127_11522143_7	1182590.BN5_03571	0.000108	48.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,1RQHU@1236|Gammaproteobacteria,1YF58@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
YHH2_k127_11522143_0	204773.HEAR3112	0.0	1101.0	COG2304@1|root,COG3419@1|root,COG2304@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,472QP@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Neisseria PilC beta-propeller domain	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
YHH2_k127_11522143_3	395494.Galf_0167	1.013e-41	162.0	COG4726@1|root,COG4726@2|Bacteria,1N9CE@1224|Proteobacteria,2VWPP@28216|Betaproteobacteria,44W26@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11522143_2	395494.Galf_0168	1.306e-94	322.0	COG4966@1|root,COG4966@2|Bacteria,1RDRS@1224|Proteobacteria,2WFYC@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV Pilus-assembly protein W	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilW
YHH2_k127_11522143_6	395494.Galf_0169	3.484e-28	117.0	COG4967@1|root,COG4967@2|Bacteria,1N7AC@1224|Proteobacteria,2VW8B@28216|Betaproteobacteria,44W3Z@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
YHH2_k127_11522143_5	395494.Galf_0170	8.97e-38	151.0	COG4970@1|root,COG4970@2|Bacteria,1NA9B@1224|Proteobacteria,2VV1S@28216|Betaproteobacteria,44W1X@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
YHH2_k127_11522143_4	395494.Galf_0171	4.076e-41	155.0	COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria,44W29@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
YHH2_k127_11522143_1	580332.Slit_2081	8.84e-166	527.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2WAJ5@28216|Betaproteobacteria,44VDR@713636|Nitrosomonadales	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
YHH2_k127_11537616_10	580332.Slit_2719	8.343e-65	225.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,44V43@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
YHH2_k127_11537616_1	580332.Slit_2718	1.211e-259	804.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,44VEH@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Mur ligase family, catalytic domain	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH2_k127_11537616_7	580332.Slit_2717	2.566e-146	473.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2W9FB@28216|Betaproteobacteria,44WEF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	-	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
YHH2_k127_11537616_6	580332.Slit_2716	2.234e-165	523.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,44V42@713636|Nitrosomonadales	28216|Betaproteobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
YHH2_k127_11537616_12	1123392.AQWL01000002_gene1866	5.243e-45	171.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,1KRV6@119069|Hydrogenophilales	119069|Hydrogenophilales	M	POTRA domain, FtsQ-type	-	-	-	-	-	-	-	-	-	-	-	-	FtsQ,POTRA_1
YHH2_k127_11537616_2	580332.Slit_2714	2.287e-249	771.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,44UZY@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
YHH2_k127_11537616_4	580332.Slit_2713	1.063e-223	696.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,44VGJ@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YHH2_k127_11537616_5	580332.Slit_2712	6.195e-179	563.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,44V9K@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
YHH2_k127_11537616_17	580332.Slit_2711	3.299e-16	79.0	2AG2M@1|root,3166Z@2|Bacteria,1PWZE@1224|Proteobacteria,2WCHD@28216|Betaproteobacteria,44W3K@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11537616_19	580332.Slit_2710	1.536e-06	51.0	COG4701@1|root,COG4701@2|Bacteria,1N8HR@1224|Proteobacteria,2VW5Y@28216|Betaproteobacteria,44W40@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
YHH2_k127_11537616_13	76114.ebB204	6.486e-39	147.0	2D3E2@1|root,32TET@2|Bacteria,1N2S5@1224|Proteobacteria,2VYYV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_11537616_11	76114.ebA5967	6.178e-62	215.0	COG1569@1|root,COG1569@2|Bacteria,1MYFF@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH2_k127_11537616_18	395494.Galf_2192	7.151e-10	59.0	COG4679@1|root,COG4679@2|Bacteria,1MZC9@1224|Proteobacteria,2VTTD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
YHH2_k127_11537616_16	927677.ALVU02000001_gene2617	6.743e-23	100.0	COG3514@1|root,COG3514@2|Bacteria,1GA67@1117|Cyanobacteria	1117|Cyanobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
YHH2_k127_11537616_15	580332.Slit_2710	7.71e-31	126.0	COG4701@1|root,COG4701@2|Bacteria,1N8HR@1224|Proteobacteria,2VW5Y@28216|Betaproteobacteria,44W40@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
YHH2_k127_11537616_8	580332.Slit_2709	3.181e-123	404.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,44WCE@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
YHH2_k127_11537616_0	580332.Slit_2708	0.0	1621.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,44V1H@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH2_k127_11537616_9	580332.Slit_2707	3.819e-72	246.0	COG0664@1|root,COG0664@2|Bacteria,1NBRS@1224|Proteobacteria,2WCFJ@28216|Betaproteobacteria,44VZA@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
YHH2_k127_11537616_3	580332.Slit_2706	3.395e-225	702.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2VJ84@28216|Betaproteobacteria,44V2G@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
YHH2_k127_11552907_0	1485544.JQKP01000001_gene1082	1.34e-302	954.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W76@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
YHH2_k127_11552907_1	580332.Slit_2225	1.526e-132	430.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VMMZ@28216|Betaproteobacteria,44WPA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,Response_reg,SBP_bac_3,dCache_1
YHH2_k127_11552907_2	1121940.AUDZ01000012_gene828	7e-43	161.0	COG1943@1|root,COG1943@2|Bacteria,1MZZT@1224|Proteobacteria,1S9JG@1236|Gammaproteobacteria,1XKZM@135619|Oceanospirillales	135619|Oceanospirillales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH2_k127_11633033_1	580332.Slit_2578	3.722e-254	788.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria,44V6I@713636|Nitrosomonadales	28216|Betaproteobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
YHH2_k127_11633033_15	697282.Mettu_0852	1.425e-78	278.0	COG1819@1|root,COG1819@2|Bacteria,1REWD@1224|Proteobacteria,1S6RC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CG	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
YHH2_k127_11633033_23	1244869.H261_01102	2.456e-55	205.0	COG1943@1|root,COG1943@2|Bacteria,1MYD2@1224|Proteobacteria	1224|Proteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_11633033_11	580332.Slit_2579	2.351e-96	318.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,44VR2@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
YHH2_k127_11633033_0	580332.Slit_2580	0.0	1263.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,44VA1@713636|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YHH2_k127_11633033_12	580332.Slit_2581	4.634e-95	316.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,44VVH@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_11633033_3	580332.Slit_2582	1.201e-215	687.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,44VY8@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_11633033_17	580332.Slit_2583	2.52e-74	257.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,44VTT@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
YHH2_k127_11633033_9	580332.Slit_2584	2.288e-133	426.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,2VINE@28216|Betaproteobacteria,44VB0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
YHH2_k127_11633033_10	580332.Slit_2585	3.741e-103	339.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,44VS6@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
YHH2_k127_11633033_6	580332.Slit_2586	1.149e-165	524.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,44VH3@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
YHH2_k127_11633033_26	292415.Tbd_0321	1.647e-49	186.0	COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria	28216|Betaproteobacteria	I	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
YHH2_k127_11633033_4	580332.Slit_2588	5.814e-195	614.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VH25@28216|Betaproteobacteria,44VN1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_11633033_29	420662.Mpe_A0377	4.313e-36	143.0	COG1077@1|root,COG1077@2|Bacteria,1RK8H@1224|Proteobacteria,2VT45@28216|Betaproteobacteria,1KP4R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH2_k127_11633033_5	580332.Slit_2589	3.276e-176	558.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,2VHZZ@28216|Betaproteobacteria,44VIK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
YHH2_k127_11633033_13	580332.Slit_2590	5.398e-95	320.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,44VV3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Phosphoribosyltransferase	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
YHH2_k127_11633033_21	395494.Galf_0241	2.228e-60	223.0	COG0457@1|root,COG0457@2|Bacteria,1N260@1224|Proteobacteria,2VTG6@28216|Betaproteobacteria,44VWA@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	ko:K12284	-	-	-	-	ko00000,ko02044	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
YHH2_k127_11633033_8	580332.Slit_2592	2.938e-142	457.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VKIQ@28216|Betaproteobacteria,44V58@713636|Nitrosomonadales	28216|Betaproteobacteria	U	AAA domain	exeA2	-	-	ko:K02450,ko:K12283	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
YHH2_k127_11633033_2	580332.Slit_2593	1.257e-222	702.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMZA@28216|Betaproteobacteria,44VH7@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II and III secretion system protein	-	-	-	ko:K02453,ko:K12282	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
YHH2_k127_11633033_35	580332.Slit_2594	9.297e-15	82.0	2DR7A@1|root,33AIK@2|Bacteria,1NGEC@1224|Proteobacteria,2VY5Y@28216|Betaproteobacteria,44W4E@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	ko:K12281	-	-	-	-	ko00000,ko02044	-	-	-	-
YHH2_k127_11633033_14	580332.Slit_2595	1.032e-81	277.0	COG3167@1|root,COG3167@2|Bacteria,1N1KE@1224|Proteobacteria,2VV3H@28216|Betaproteobacteria,44W3R@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	carbon utilization	-	-	-	ko:K12280	-	-	-	-	ko00000,ko02044	-	-	-	T2SSM
YHH2_k127_11633033_18	580332.Slit_2596	3.135e-74	256.0	COG3166@1|root,COG3166@2|Bacteria,1RHH0@1224|Proteobacteria,2WB06@28216|Betaproteobacteria,44W3U@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Fimbrial assembly protein (PilN)	-	-	-	-	-	-	-	-	-	-	-	-	PilN
YHH2_k127_11633033_7	580332.Slit_2597	4.848e-148	474.0	COG4972@1|root,COG4972@2|Bacteria,1N0HS@1224|Proteobacteria,2VQYY@28216|Betaproteobacteria,44VPT@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Pilus assembly protein	-	-	-	ko:K12279	-	-	-	-	ko00000,ko02044	-	-	-	PilM_2
YHH2_k127_11633033_20	1198452.Jab_2c02720	1.449e-66	261.0	COG1361@1|root,COG3420@1|root,COG1361@2|Bacteria,COG3420@2|Bacteria,1RGIY@1224|Proteobacteria,2WBGP@28216|Betaproteobacteria,475S9@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH2_k127_11633033_30	1095769.CAHF01000011_gene2531	1.345e-29	139.0	COG3210@1|root,COG3391@1|root,COG3420@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3420@2|Bacteria,1R4VM@1224|Proteobacteria,2VPC1@28216|Betaproteobacteria,475GT@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	alginic acid biosynthetic process	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	-
YHH2_k127_11633033_22	118161.KB235922_gene1555	5.445e-57	204.0	COG4636@1|root,COG4636@2|Bacteria,1GJU8@1117|Cyanobacteria,3VMNU@52604|Pleurocapsales	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
YHH2_k127_11633033_16	522306.CAP2UW1_2998	1.688e-78	265.0	COG4636@1|root,COG4636@2|Bacteria,1RI9E@1224|Proteobacteria	1224|Proteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
YHH2_k127_11633033_19	857087.Metme_0721	1.832e-68	237.0	COG4636@1|root,COG4636@2|Bacteria,1RDIC@1224|Proteobacteria,1S6NM@1236|Gammaproteobacteria,1XFTV@135618|Methylococcales	135618|Methylococcales	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
YHH2_k127_11633033_34	204773.HEAR1946	1.885e-20	97.0	COG4726@1|root,COG4726@2|Bacteria,1N9C7@1224|Proteobacteria,2VWCD@28216|Betaproteobacteria,47525@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K12286	-	-	-	-	ko00000,ko02044	-	-	-	-
YHH2_k127_11633033_25	580332.Slit_2601	4.593e-55	205.0	COG2165@1|root,COG2165@2|Bacteria,1RK34@1224|Proteobacteria,2WGNH@28216|Betaproteobacteria,44W3Y@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K12285	-	-	-	-	ko00000,ko02044	-	-	-	N_methyl
YHH2_k127_11633033_24	697282.Mettu_3216	3.149e-55	199.0	COG4967@1|root,COG4967@2|Bacteria,1RKKA@1224|Proteobacteria	1224|Proteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K10927	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
YHH2_k127_11633033_32	247490.KSU1_B0229	2.782e-23	105.0	2ECCV@1|root,336B4@2|Bacteria,2J3S9@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11633033_27	395494.Galf_0230	1.541e-40	156.0	COG4970@1|root,COG4970@2|Bacteria,1N8HW@1224|Proteobacteria,2VWJK@28216|Betaproteobacteria,44W3X@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K10926	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	GspH,N_methyl
YHH2_k127_11633033_28	1123354.AUDR01000011_gene1495	2.161e-37	143.0	COG4190@1|root,COG4190@2|Bacteria,1N0FF@1224|Proteobacteria,2VUDR@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
YHH2_k127_11633033_31	1173027.Mic7113_4762	3.413e-26	110.0	COG3668@1|root,COG3668@2|Bacteria,1G7UC@1117|Cyanobacteria,1HDRH@1150|Oscillatoriales	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_11633033_36	1504981.KO116_2899	2.256e-08	58.0	2EKK5@1|root,33EA0@2|Bacteria,1NI6Y@1224|Proteobacteria,1SGCX@1236|Gammaproteobacteria,1XPXV@135619|Oceanospirillales	135619|Oceanospirillales	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
YHH2_k127_11633033_33	1268635.Loa_02938	8.225e-23	102.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	mshB	-	-	ko:K02458,ko:K10924,ko:K10925	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
YHH2_k127_11672484_0	580332.Slit_2262	0.0	1304.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,44V6H@713636|Nitrosomonadales	28216|Betaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
YHH2_k127_11672484_4	580332.Slit_2259	1.301e-144	461.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,44V7M@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YHH2_k127_11672484_5	395494.Galf_0641	5.206e-107	353.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria,44VDH@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
YHH2_k127_11672484_3	580332.Slit_2257	9.019e-146	464.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,44VK5@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
YHH2_k127_11672484_8	580332.Slit_2256	1.389e-71	244.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,44VWG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
YHH2_k127_11672484_2	580332.Slit_2255	9.771e-246	764.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,44V1D@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YHH2_k127_11672484_7	580332.Slit_2254	3.206e-79	265.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,44VSJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YHH2_k127_11672484_9	580332.Slit_2253	2.88e-58	203.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,44VWW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM iron-sulfur cluster assembly protein IscA	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
YHH2_k127_11672484_6	580332.Slit_2252	2.243e-81	276.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,44VVM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
YHH2_k127_11672484_1	580332.Slit_2251	0.0	1088.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,44VHV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
YHH2_k127_11672484_10	640081.Dsui_2376	2.244e-13	70.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,2KWP0@206389|Rhodocyclales	206389|Rhodocyclales	C	Ferredoxin, 2Fe-2S type, ISC system	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
YHH2_k127_11704704_3	279714.FuraDRAFT_1304	1.19e-56	206.0	COG0288@1|root,COG0288@2|Bacteria,1RKKR@1224|Proteobacteria,2VTB7@28216|Betaproteobacteria,2KSCZ@206351|Neisseriales	206351|Neisseriales	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
YHH2_k127_11704704_2	580332.Slit_1173	2.473e-81	284.0	28HEC@1|root,2Z7QS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11704704_0	1485544.JQKP01000011_gene738	4.744e-184	585.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VP8B@28216|Betaproteobacteria,44VEG@713636|Nitrosomonadales	28216|Betaproteobacteria	EH	Anthranilate synthase component I domain protein	-	-	2.6.1.85	ko:K01665,ko:K13950	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
YHH2_k127_11704704_1	580332.Slit_0472	3e-123	398.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,44VS3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
YHH2_k127_11704952_0	686340.Metal_0607	1.882e-164	526.0	COG1111@1|root,COG4889@1|root,COG1111@2|Bacteria,COG4889@2|Bacteria,1QZFK@1224|Proteobacteria	1224|Proteobacteria	L	type iii restriction	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,Mrr_cat_2,N6_Mtase,ResIII
YHH2_k127_11704952_1	1279009.ADICEAN_01460	3.015e-09	58.0	COG3093@1|root,COG3093@2|Bacteria,4NSBZ@976|Bacteroidetes,47R1U@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
YHH2_k127_11727401_5	580332.Slit_0659	4.294e-71	247.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2VUA6@28216|Betaproteobacteria,44WFX@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
YHH2_k127_11727401_8	748247.AZKH_4320	4.024e-54	194.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria,2KW78@206389|Rhodocyclales	206389|Rhodocyclales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
YHH2_k127_11727401_1	580332.Slit_0657	5.408e-140	451.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,44VFP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH2_k127_11727401_6	580332.Slit_0656	6.729e-68	235.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2VSI6@28216|Betaproteobacteria,44VWD@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
YHH2_k127_11727401_3	580332.Slit_0655	2.546e-77	260.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2VQGE@28216|Betaproteobacteria,44VUK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
YHH2_k127_11727401_0	580332.Slit_0654	3.585e-196	617.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2VH6S@28216|Betaproteobacteria,44VKD@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
YHH2_k127_11727401_10	580332.Slit_1827	4.328e-05	51.0	COG3167@1|root,COG3167@2|Bacteria,1N0IK@1224|Proteobacteria,2VXJE@28216|Betaproteobacteria,44WKP@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	carbon utilization	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11727401_7	1121861.KB899951_gene2303	2.17e-56	218.0	COG3209@1|root,COG3209@2|Bacteria,1PHC1@1224|Proteobacteria,2V8X0@28211|Alphaproteobacteria,2JXWU@204441|Rhodospirillales	204441|Rhodospirillales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YHH2_k127_11727401_9	667015.Bacsa_0078	8.024e-15	80.0	COG1848@1|root,COG1848@2|Bacteria,4NNGQ@976|Bacteroidetes,2FUUE@200643|Bacteroidia,4AUZ9@815|Bacteroidaceae	976|Bacteroidetes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
YHH2_k127_11727401_2	580332.Slit_0653	2.77e-102	335.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,44V83@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
YHH2_k127_11727401_4	580332.Slit_0652	3.144e-76	259.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,44VG2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
YHH2_k127_11739388_12	1182590.BN5_03571	3.583e-06	49.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,1RQHU@1236|Gammaproteobacteria,1YF58@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
YHH2_k127_11739388_4	29581.BW37_01552	4.634e-96	324.0	COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria,2VSGX@28216|Betaproteobacteria,476QV@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
YHH2_k127_11739388_1	1349767.GJA_3316	4.215e-179	570.0	COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria,2VJB7@28216|Betaproteobacteria,475XF@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
YHH2_k127_11739388_9	717773.Thicy_0537	1.511e-30	127.0	COG5499@1|root,COG5499@2|Bacteria,1N89F@1224|Proteobacteria,1SBAA@1236|Gammaproteobacteria,461FW@72273|Thiotrichales	72273|Thiotrichales	K	regulator	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
YHH2_k127_11739388_5	1121878.AUGL01000021_gene2798	1.95e-92	316.0	COG5001@1|root,COG5001@2|Bacteria,1R1WN@1224|Proteobacteria	1224|Proteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
YHH2_k127_11739388_2	580332.Slit_2685	1.716e-146	466.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,44V3G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
YHH2_k127_11739388_6	580332.Slit_2684	1.121e-87	290.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,44VRP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
YHH2_k127_11739388_8	580332.Slit_2683	1.243e-52	190.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VUY2@28216|Betaproteobacteria,44VZ2@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Cell division protein ZapA	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
YHH2_k127_11739388_10	580332.Slit_2682	2.017e-25	106.0	2EG8X@1|root,33A0Q@2|Bacteria,1NMVN@1224|Proteobacteria,2VY0V@28216|Betaproteobacteria,44W3H@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11739388_3	795666.MW7_2482	3.666e-130	437.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,1K0NI@119060|Burkholderiaceae	28216|Betaproteobacteria	H	receptor	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
YHH2_k127_11739388_7	580332.Slit_2680	2.331e-69	241.0	2ARZT@1|root,31HBY@2|Bacteria,1RM6G@1224|Proteobacteria,2VT5G@28216|Betaproteobacteria,44WIK@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11739388_0	580332.Slit_2679	9.867e-307	947.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,44V3U@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH2_k127_11751456_7	580332.Slit_2952	1.266e-40	151.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,44W0G@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
YHH2_k127_11751456_0	580332.Slit_2953	3.019e-250	779.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,44VMC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
YHH2_k127_11751456_1	292415.Tbd_2353	7.465e-103	352.0	COG0642@1|root,COG0642@2|Bacteria,1PA1G@1224|Proteobacteria,2WGUD@28216|Betaproteobacteria,1KSJ4@119069|Hydrogenophilales	119069|Hydrogenophilales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
YHH2_k127_11751456_2	1163617.SCD_n00405	1.289e-99	330.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2WEGC@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulatory protein ompR	-	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_11751456_6	1163409.UUA_11268	1.229e-44	171.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,1SGXK@1236|Gammaproteobacteria,1X6ZE@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11751456_5	580332.Slit_1495	2.191e-50	186.0	COG2920@1|root,COG2920@2|Bacteria,1NAQC@1224|Proteobacteria,2VWA3@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
YHH2_k127_11751456_9	395494.Galf_1666	0.0002547	45.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2VI7W@28216|Betaproteobacteria,44W45@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH2_k127_11751456_3	395494.Galf_0986	4.296e-87	299.0	COG3177@1|root,COG3177@2|Bacteria,1MX0V@1224|Proteobacteria,2VIFD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH2_k127_11804468_15	1123368.AUIS01000005_gene299	7.394e-79	301.0	COG4932@1|root,COG4932@2|Bacteria,1QW47@1224|Proteobacteria,1RQU1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1
YHH2_k127_11804468_22	471853.Bcav_2782	3.992e-33	151.0	COG1404@1|root,COG2911@1|root,COG4932@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,2GYXK@201174|Actinobacteria	201174|Actinobacteria	M	Invasin, domain 3	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Invasin_D3
YHH2_k127_11804468_6	580332.Slit_0114	7.636e-185	584.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,44UZZ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
YHH2_k127_11804468_9	1485544.JQKP01000001_gene907	4.381e-164	533.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,44VC5@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
YHH2_k127_11804468_3	1163617.SCD_n02945	7.873e-212	679.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria	28216|Betaproteobacteria	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
YHH2_k127_11804468_17	580332.Slit_0111	4.965e-69	238.0	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,2VSVR@28216|Betaproteobacteria,44VWM@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Pilus assembly protein, PilP	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
YHH2_k127_11804468_13	580332.Slit_0110	2.1e-91	304.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria,44VQQ@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
YHH2_k127_11804468_16	580332.Slit_0109	4.145e-77	262.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,2VN9T@28216|Betaproteobacteria,44VS1@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Fimbrial assembly protein (PilN)	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
YHH2_k127_11804468_4	580332.Slit_0108	2.524e-203	636.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria,44VBU@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
YHH2_k127_11804468_0	580332.Slit_0107	0.0	1231.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,44V5E@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Penicillin-binding protein OB-like domain	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
YHH2_k127_11804468_14	580332.Slit_0106	7.597e-89	296.0	COG2413@1|root,COG2413@2|Bacteria,1RFTH@1224|Proteobacteria,2VJC9@28216|Betaproteobacteria,44VRE@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11804468_5	580332.Slit_0037	2.467e-201	630.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria,44VC7@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
YHH2_k127_11804468_12	580332.Slit_0038	2.111e-122	394.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria,44V31@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
YHH2_k127_11804468_2	395494.Galf_0153	6.136e-247	765.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,44V4H@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH2_k127_11804468_20	1236959.BAMT01000007_gene2678	1.13e-53	196.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria,2KMSI@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
YHH2_k127_11804468_8	580332.Slit_0041	1.063e-164	520.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria,44V55@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
YHH2_k127_11804468_23	765914.ThisiDRAFT_2195	7.718e-10	63.0	2EG83@1|root,335DA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11804468_21	56110.Oscil6304_1724	2.245e-53	191.0	COG1848@1|root,COG1848@2|Bacteria,1G5K6@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_11804468_18	580332.Slit_2754	3.592e-63	223.0	2DXCX@1|root,344GN@2|Bacteria,1N5VS@1224|Proteobacteria,2WHGX@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11804468_11	1485544.JQKP01000020_gene60	4.111e-124	404.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,44V3F@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YHH2_k127_11804468_10	395494.Galf_0147	1.241e-135	439.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,44V0P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
YHH2_k127_11804468_7	580332.Slit_0044	1.039e-182	580.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,44VEF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
YHH2_k127_11804468_1	580332.Slit_0045	1.595e-297	929.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,44V59@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
YHH2_k127_11804468_19	580332.Slit_0046	6.336e-56	196.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,44VMI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
YHH2_k127_11852045_5	580332.Slit_2444	3.952e-23	98.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,44V7T@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH2_k127_11852045_1	1192034.CAP_8837	2.976e-104	351.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,4304Z@68525|delta/epsilon subdivisions,2WVJ8@28221|Deltaproteobacteria,2YV3F@29|Myxococcales	28221|Deltaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	topI	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
YHH2_k127_11852045_0	521674.Plim_2651	4.589e-259	810.0	COG0286@1|root,COG0286@2|Bacteria,2IXEQ@203682|Planctomycetes	203682|Planctomycetes	V	COG0286 Type I restriction-modification system	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
YHH2_k127_11852045_3	697282.Mettu_1948	1.062e-58	208.0	COG0286@1|root,COG1669@1|root,COG0286@2|Bacteria,COG1669@2|Bacteria,1RGUJ@1224|Proteobacteria,1S6NJ@1236|Gammaproteobacteria,1XFQG@135618|Methylococcales	135618|Methylococcales	V	TIGRFAM Nucleotidyltransferase substrate binding protein, HI0074	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
YHH2_k127_11852045_4	697282.Mettu_1947	1.964e-43	163.0	COG1708@1|root,COG1708@2|Bacteria,1NBM4@1224|Proteobacteria,1SCHR@1236|Gammaproteobacteria,1XFXB@135618|Methylococcales	1236|Gammaproteobacteria	L	PFAM Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH2_k127_11852045_2	330214.NIDE2624	7.892e-104	351.0	COG0732@1|root,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
YHH2_k127_11852688_5	65093.PCC7418_1354	2.933e-05	56.0	COG3307@1|root,COG3307@2|Bacteria,1G15X@1117|Cyanobacteria	1117|Cyanobacteria	M	O-antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH2_k127_11852688_4	1454007.JAUG01000011_gene2310	1.315e-17	94.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
YHH2_k127_11852688_1	1112274.KI911560_gene677	2.032e-50	184.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,2VRST@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH2_k127_11852688_2	247490.KSU1_C0662	1.672e-28	116.0	COG4456@1|root,COG4456@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_11852688_3	426114.THI_2526	3.795e-22	101.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,2VU9A@28216|Betaproteobacteria,1KMB9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
YHH2_k127_11852688_0	580332.Slit_2387	1.317e-167	529.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,44VPF@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YHH2_k127_1197737_8	1454004.AW11_03603	4.035e-42	177.0	2DM3R@1|root,31KU1@2|Bacteria,1MYVS@1224|Proteobacteria,2VTP5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1197737_12	1123372.AUIT01000009_gene336	4.478e-27	128.0	COG2165@1|root,COG2165@2|Bacteria,2GHZ8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH2_k127_1197737_7	29581.BW37_03992	4.019e-47	178.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K10927,ko:K12285	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl,T2SSG
YHH2_k127_1197737_5	395494.Galf_2321	1.741e-70	244.0	COG4567@1|root,COG4567@2|Bacteria,1NYHM@1224|Proteobacteria	1224|Proteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg
YHH2_k127_1197737_18	62928.azo1372	1.116e-07	53.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_1197737_2	580332.Slit_2692	3.653e-219	683.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,44V9D@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YHH2_k127_1197737_15	580332.Slit_2693	1.749e-23	106.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,44WJY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
YHH2_k127_1197737_10	395494.Galf_0299	5.319e-30	121.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,44WJY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
YHH2_k127_1197737_13	580332.Slit_2693	2.827e-25	113.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,44WJY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
YHH2_k127_1197737_4	580332.Slit_2695	1.516e-113	368.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VJNI@28216|Betaproteobacteria,44VQX@713636|Nitrosomonadales	28216|Betaproteobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
YHH2_k127_1197737_0	580332.Slit_2696	0.0	1153.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2VH5Q@28216|Betaproteobacteria,44V4W@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
YHH2_k127_1197737_6	580332.Slit_0516	3.38e-64	224.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2VUEV@28216|Betaproteobacteria,44VXM@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Thioesterase-like superfamily	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
YHH2_k127_1197737_9	768671.ThimaDRAFT_2816	1.216e-33	134.0	COG1487@1|root,COG1487@2|Bacteria,1N0W5@1224|Proteobacteria,1S703@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH2_k127_1197737_11	768671.ThimaDRAFT_2817	4.073e-27	113.0	COG4456@1|root,COG4456@2|Bacteria,1N7FM@1224|Proteobacteria,1SIQE@1236|Gammaproteobacteria,1WZKI@135613|Chromatiales	135613|Chromatiales	S	SpoVT AbrB	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_1197737_1	324925.Ppha_2832	1.732e-278	865.0	COG1106@1|root,COG1106@2|Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
YHH2_k127_1197737_14	518766.Rmar_2421	2.111e-24	108.0	COG1569@1|root,COG1569@2|Bacteria	2|Bacteria	S	PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
YHH2_k127_1197737_16	232348.ADXL01000020_gene1107	9.754e-15	76.0	COG3905@1|root,COG3905@2|Bacteria	2|Bacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
YHH2_k127_1197737_3	580332.Slit_0515	2.168e-187	586.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,44VJD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YHH2_k127_1285725_0	580332.Slit_1976	0.0	1287.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,44V5I@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YHH2_k127_1285725_1	580332.Slit_1977	1.965e-177	570.0	COG0741@1|root,COG1388@1|root,COG3170@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,COG3170@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,44V2P@713636|Nitrosomonadales	28216|Betaproteobacteria	M	LysM domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
YHH2_k127_1287661_0	580332.Slit_2005	1.475e-123	400.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,2VJ6J@28216|Betaproteobacteria,44W9Z@713636|Nitrosomonadales	28216|Betaproteobacteria	O	SMART heat shock protein DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
YHH2_k127_1287661_1	1485544.JQKP01000015_gene2077	2.534e-92	307.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,44WEY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function, DUF480	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
YHH2_k127_1311842_5	580332.Slit_2752	3.917e-51	186.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,44VGZ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM RNA-binding protein AU-1 Ribonuclease E G	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
YHH2_k127_1311842_3	580332.Slit_2751	1.876e-91	309.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria,44VR4@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
YHH2_k127_1311842_4	580332.Slit_2750	2.909e-82	284.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,44VPN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
YHH2_k127_1311842_6	305700.B447_19909	7.069e-36	141.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,2KWQI@206389|Rhodocyclales	206389|Rhodocyclales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
YHH2_k127_1311842_2	580332.Slit_2748	8.703e-109	355.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,44VUN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YHH2_k127_1311842_0	580332.Slit_2747	1.923e-207	652.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,44V3D@713636|Nitrosomonadales	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_1311842_1	580332.Slit_2746	3.757e-155	491.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,44VDQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YHH2_k127_1321227_0	946483.Cenrod_1456	5.77e-213	671.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2VNEJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
YHH2_k127_1321227_1	62928.azo0702	2.956e-117	398.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,2VIXN@28216|Betaproteobacteria,2KV6G@206389|Rhodocyclales	206389|Rhodocyclales	V	Inner membrane protein CreD	-	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
YHH2_k127_1321227_3	377629.TERTU_0622	5.086e-33	134.0	29W5V@1|root,30HQZ@2|Bacteria,1RFZX@1224|Proteobacteria,1S4QF@1236|Gammaproteobacteria,2PQ6M@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4184,YdjM
YHH2_k127_1321227_2	701176.VIBRN418_08212	3.17e-115	378.0	COG3591@1|root,COG3591@2|Bacteria,1QEUY@1224|Proteobacteria,1TBRI@1236|Gammaproteobacteria,1Y0KC@135623|Vibrionales	135623|Vibrionales	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1321227_4	667632.KB890220_gene2731	9.841e-26	106.0	COG3744@1|root,COG3744@2|Bacteria,1RJ4K@1224|Proteobacteria,2VTJR@28216|Betaproteobacteria,1K85X@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_1321533_1	338969.Rfer_0818	9.906e-107	350.0	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,2VHDT@28216|Betaproteobacteria	28216|Betaproteobacteria	E	phosphoserine phosphatase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
YHH2_k127_1321533_2	580332.Slit_2837	7.325e-70	246.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2WCG6@28216|Betaproteobacteria,44W0X@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1321533_3	580332.Slit_2838	3.639e-65	228.0	28P01@1|root,324AA@2|Bacteria,1QAPE@1224|Proteobacteria,2W7MD@28216|Betaproteobacteria,44W0D@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1321533_4	580332.Slit_2842	7.058e-53	192.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,2VU9A@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
YHH2_k127_1321533_5	870187.Thini_1486	1.04e-32	134.0	2C3ZQ@1|root,32SCF@2|Bacteria,1N27R@1224|Proteobacteria,1S4HC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MEKHLA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MEKHLA
YHH2_k127_1321533_0	580332.Slit_2844	0.0	1241.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,44VHM@713636|Nitrosomonadales	28216|Betaproteobacteria	L	UvrD-like helicase C-terminal domain	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YHH2_k127_1321533_6	426114.THI_2568	1.297e-28	117.0	COG2161@1|root,COG2161@2|Bacteria,1PP42@1224|Proteobacteria,2VYF5@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_1329321_1	395494.Galf_2495	1.426e-62	222.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,2VKGK@28216|Betaproteobacteria,44WAC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Phospholipase A1	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
YHH2_k127_1329321_0	580332.Slit_2697	1.347e-147	470.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,44V26@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
YHH2_k127_1334480_0	266264.Rmet_1428	2.733e-280	875.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1K0GW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YHH2_k127_1334480_1	580332.Slit_1293	1.419e-160	508.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,44VIF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YHH2_k127_1334480_7	580332.Slit_1294	3.726e-89	298.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VRM9@28216|Betaproteobacteria,44VRI@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
YHH2_k127_1334480_4	580332.Slit_1295	3.064e-131	422.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,44VB8@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphorylase superfamily	mtaP	-	2.4.2.28	ko:K00772,ko:K03815	ko00230,ko00270,ko01100,ko01110,map00230,map00270,map01100,map01110	M00034	R01402,R02297	RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YHH2_k127_1334480_6	580332.Slit_1296	1.893e-94	311.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria,44VSV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
YHH2_k127_1334480_3	395494.Galf_1204	1.928e-131	430.0	COG1226@1|root,COG3273@1|root,COG1226@2|Bacteria,COG3273@2|Bacteria,1MU1R@1224|Proteobacteria,2WEJI@28216|Betaproteobacteria,44V2J@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
YHH2_k127_1334480_2	1095769.CAHF01000013_gene3378	1.251e-159	515.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria,473TS@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
YHH2_k127_1334480_5	580332.Slit_1346	1.468e-115	374.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,44VV7@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
YHH2_k127_1408283_9	335283.Neut_2248	4.457e-08	54.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,3723W@32003|Nitrosomonadales	28216|Betaproteobacteria	E	TIGRFAM HAD-superfamily hydrolase, subfamily IB (PSPase-like)	-	-	-	-	-	-	-	-	-	-	-	-	HAD
YHH2_k127_1408283_8	580332.Slit_0632	3.927e-24	108.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,44W2X@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
YHH2_k127_1408283_6	1485544.JQKP01000011_gene769	7.376e-62	214.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,44VY0@713636|Nitrosomonadales	28216|Betaproteobacteria	FG	HIT domain	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
YHH2_k127_1408283_7	580332.Slit_0630	1.384e-52	186.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,44W06@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
YHH2_k127_1408283_5	580332.Slit_0629	3.538e-71	242.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,44VV6@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
YHH2_k127_1408283_1	1485544.JQKP01000011_gene772	8.155e-152	481.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,44VIE@713636|Nitrosomonadales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YHH2_k127_1408283_0	580332.Slit_0627	7.46e-154	486.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,44UZI@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Histidine biosynthesis protein	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YHH2_k127_1408283_3	395494.Galf_0435	2.171e-110	360.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,44V1Z@713636|Nitrosomonadales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YHH2_k127_1408283_2	580332.Slit_0625	7.134e-117	377.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,44VGH@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
YHH2_k127_1408283_4	580332.Slit_0624	1.077e-90	300.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHX2@28216|Betaproteobacteria,44V69@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_141194_0	580332.Slit_1660	8.844e-241	748.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44VC4@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DEAD DEAH box helicase domain protein	rhlE1	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
YHH2_k127_141194_1	232348.ADXL01000091_gene464	4.491e-43	161.0	COG3577@1|root,COG3577@2|Bacteria,1G6TW@1117|Cyanobacteria	1117|Cyanobacteria	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas
YHH2_k127_1481909_3	580332.Slit_0922	1.472e-212	667.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,2VHFE@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Chloride channel	clcA	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
YHH2_k127_1481909_9	292415.Tbd_0499	1.373e-99	334.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,2VKTC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
YHH2_k127_1481909_0	525897.Dbac_2914	0.0	1061.0	COG0296@1|root,COG0366@1|root,COG0296@2|Bacteria,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,42P6Z@68525|delta/epsilon subdivisions,2WK5W@28221|Deltaproteobacteria,2MG3K@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Alpha amylase, catalytic	treS	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
YHH2_k127_1481909_10	525897.Dbac_2913	5.302e-93	314.0	COG0561@1|root,COG0561@2|Bacteria,1QFFG@1224|Proteobacteria,42R6U@68525|delta/epsilon subdivisions,2WN0Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	S6PP
YHH2_k127_1481909_1	525897.Dbac_2912	0.0	1032.0	COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,42NCP@68525|delta/epsilon subdivisions,2WJSM@28221|Deltaproteobacteria,2MEQ6@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Sucrose synthase	-	-	2.4.1.14	ko:K00696	ko00500,ko01100,map00500,map01100	-	R00766	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth
YHH2_k127_1481909_8	1163617.SCD_n01200	1.643e-102	344.0	COG0524@1|root,COG0524@2|Bacteria,1PCFU@1224|Proteobacteria,2VK5G@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PfkB domain protein	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH2_k127_1481909_14	580332.Slit_0921	3.496e-28	122.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VV2D@28216|Betaproteobacteria	28216|Betaproteobacteria	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
YHH2_k127_1481909_12	580332.Slit_0660	2.011e-59	209.0	COG1846@1|root,COG1846@2|Bacteria,1PW9W@1224|Proteobacteria,2VUDE@28216|Betaproteobacteria	28216|Betaproteobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
YHH2_k127_1481909_7	395494.Galf_0798	1.692e-118	386.0	COG0289@1|root,COG0289@2|Bacteria,1RAV8@1224|Proteobacteria,2VZHT@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Dihydrodipicolinate reductase, C-terminus	-	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
YHH2_k127_1481909_4	580332.Slit_2865	2.605e-177	566.0	COG0025@1|root,COG0025@2|Bacteria,1QCR7@1224|Proteobacteria,2W845@28216|Betaproteobacteria,44WDM@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YHH2_k127_1481909_2	1123279.ATUS01000005_gene3191	7.61e-263	818.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1J4RN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
YHH2_k127_1481909_6	535289.Dtpsy_1574	1.767e-129	419.0	COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,2VN85@28216|Betaproteobacteria,4AB4W@80864|Comamonadaceae	28216|Betaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YHH2_k127_1481909_15	237609.PSAKL28_31610	2.819e-18	88.0	COG1734@1|root,COG1734@2|Bacteria,1N7D8@1224|Proteobacteria,1SCG1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	DnaK suppressor protein	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
YHH2_k127_1481909_5	580332.Slit_2188	9.92e-155	491.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria	1224|Proteobacteria	Q	Methyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
YHH2_k127_1481909_16	411469.EUBHAL_01995	1.624e-06	53.0	COG2026@1|root,COG2026@2|Bacteria,1VCJ7@1239|Firmicutes,24Q49@186801|Clostridia,25XS6@186806|Eubacteriaceae	186801|Clostridia	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_1481909_13	381666.H16_B0114	1.307e-32	130.0	COG1396@1|root,COG1396@2|Bacteria,1N1H0@1224|Proteobacteria,2VV0J@28216|Betaproteobacteria,1K978@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
YHH2_k127_1481909_11	926561.KB900618_gene458	2.668e-69	243.0	2CAR6@1|root,31TEC@2|Bacteria,1V8Q1@1239|Firmicutes,24KQ9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1482157_5	1182590.BN5_03571	4.567e-05	47.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,1RQHU@1236|Gammaproteobacteria,1YF58@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
YHH2_k127_1482157_4	580332.Slit_2051	7.481e-78	264.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2VS28@28216|Betaproteobacteria,44VU1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome	cybB	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
YHH2_k127_1482157_1	580332.Slit_2050	2.568e-158	504.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,44VBA@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
YHH2_k127_1482157_3	580332.Slit_2049	7.734e-98	325.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,44VPX@713636|Nitrosomonadales	28216|Betaproteobacteria	M	MlaA lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
YHH2_k127_1482157_0	580332.Slit_1262	2.766e-167	530.0	COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,2VHAG@28216|Betaproteobacteria,44VBP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
YHH2_k127_1482157_2	1097668.BYI23_A009310	6.517e-112	362.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria,1K289@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
YHH2_k127_1532315_1	395494.Galf_2333	6.755e-104	342.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria,44VBW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
YHH2_k127_1532315_2	580332.Slit_0670	2.061e-81	275.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,44VQD@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
YHH2_k127_1532315_0	395494.Galf_2331	1.655e-128	413.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,44V3Q@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
YHH2_k127_1559721_0	580332.Slit_2130	1.138e-267	825.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,44V2Z@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Hsp70 protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YHH2_k127_1559721_3	580332.Slit_2129	1.314e-82	277.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2VSEQ@28216|Betaproteobacteria,44VPQ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YHH2_k127_1559721_7	497321.C664_06223	3.839e-39	148.0	COG2929@1|root,COG2929@2|Bacteria,1NCTW@1224|Proteobacteria,2VX68@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
YHH2_k127_1559721_10	1100720.ALKN01000030_gene1157	3.584e-22	100.0	COG3514@1|root,COG3514@2|Bacteria,1NGCR@1224|Proteobacteria,2VXYG@28216|Betaproteobacteria,4AFNC@80864|Comamonadaceae	28216|Betaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
YHH2_k127_1559721_2	1266925.JHVX01000002_gene993	1.937e-143	475.0	COG4715@1|root,COG4715@2|Bacteria,1R60K@1224|Proteobacteria	1224|Proteobacteria	S	Zinc finger, swim domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
YHH2_k127_1559721_6	1348657.M622_19440	1.389e-40	151.0	COG4453@1|root,COG4453@2|Bacteria,1N33F@1224|Proteobacteria,2VVAM@28216|Betaproteobacteria,2KYZ1@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
YHH2_k127_1559721_4	83406.HDN1F_22990	2.795e-79	268.0	COG0454@1|root,COG0454@2|Bacteria,1RHV9@1224|Proteobacteria,1S3D1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Pfam Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
YHH2_k127_1559721_1	580332.Slit_2128	1.727e-211	661.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2VHWT@28216|Betaproteobacteria,44UYH@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Nucleoside H+ symporter	hcaT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
YHH2_k127_1559721_5	768671.ThimaDRAFT_4871	1.58e-58	205.0	COG1848@1|root,COG1848@2|Bacteria,1N5DS@1224|Proteobacteria,1SQM5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
YHH2_k127_1559721_8	768671.ThimaDRAFT_4872	4.888e-32	126.0	COG4118@1|root,COG4118@2|Bacteria,1NKGM@1224|Proteobacteria,1SJGX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_1559721_9	580332.Slit_2128	9.948e-30	120.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2VHWT@28216|Betaproteobacteria,44UYH@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Nucleoside H+ symporter	hcaT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
YHH2_k127_1615569_4	580332.Slit_1312	8.274e-137	441.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VTG4@28216|Betaproteobacteria,44VV5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Ankyrin	tnkS	-	2.4.2.30	ko:K10799	-	-	-	-	ko00000,ko01000,ko03032,ko03036	-	-	-	Ank,Ank_2,Ank_4
YHH2_k127_1615569_5	580332.Slit_1312	2.035e-92	312.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VTG4@28216|Betaproteobacteria,44VV5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Ankyrin	tnkS	-	2.4.2.30	ko:K10799	-	-	-	-	ko00000,ko01000,ko03032,ko03036	-	-	-	Ank,Ank_2,Ank_4
YHH2_k127_1615569_0	580332.Slit_1315	0.0	1180.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,44VAI@713636|Nitrosomonadales	28216|Betaproteobacteria	L	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
YHH2_k127_1615569_3	582744.Msip34_0727	2.637e-141	477.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH2_k127_1615569_7	1485544.JQKP01000019_gene8	7.284e-40	169.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
YHH2_k127_1615569_1	580332.Slit_2138	0.0	1118.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,44V96@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC transporter C-terminal domain	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH2_k127_1615569_6	580332.Slit_2139	3.948e-69	237.0	2A86F@1|root,30X7C@2|Bacteria,1PJ0W@1224|Proteobacteria,2W7KJ@28216|Betaproteobacteria,44W04@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1615569_2	1485544.JQKP01000010_gene793	1.519e-195	642.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2W8ZJ@28216|Betaproteobacteria,44WED@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
YHH2_k127_1615569_9	1163617.SCD_n00207	1.953e-24	111.0	2E33J@1|root,32Y3P@2|Bacteria,1N9JJ@1224|Proteobacteria,2VXE1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1615569_8	316067.Geob_1730	2.746e-27	115.0	COG4190@1|root,COG4190@2|Bacteria,1N98Y@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
YHH2_k127_1682425_2	580332.Slit_0649	5.436e-101	331.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,44VB2@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Sigma-70 factor, region 1.2	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
YHH2_k127_1682425_4	580332.Slit_0648	2.538e-63	222.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria,44W0U@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
YHH2_k127_1682425_1	580332.Slit_0647	4.756e-122	392.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,44VQB@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
YHH2_k127_1682425_3	1163617.SCD_n00603	1.025e-73	255.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome C1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
YHH2_k127_1682425_0	292415.Tbd_1832	2.307e-136	437.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,1KRDP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
YHH2_k127_1712220_1	580332.Slit_0514	3.486e-100	330.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria,44V24@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
YHH2_k127_1712220_3	1038869.AXAN01000162_gene3360	2.615e-34	139.0	COG5642@1|root,COG5642@2|Bacteria,1NAEY@1224|Proteobacteria,2VXA6@28216|Betaproteobacteria,1K881@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
YHH2_k127_1712220_2	316058.RPB_4184	1.791e-41	157.0	COG5654@1|root,COG5654@2|Bacteria,1N0C8@1224|Proteobacteria,2UDMZ@28211|Alphaproteobacteria,3K0GE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
YHH2_k127_1712220_5	522306.CAP2UW1_4384	7.826e-29	117.0	COG2026@1|root,COG2026@2|Bacteria,1QDRK@1224|Proteobacteria,2VYUW@28216|Betaproteobacteria	28216|Betaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
YHH2_k127_1712220_4	522306.CAP2UW1_4383	1.114e-31	128.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
YHH2_k127_1712220_0	580332.Slit_0515	1.655e-140	447.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,44VJD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YHH2_k127_1718315_6	395494.Galf_2653	1.82e-31	124.0	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,2VU5V@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	-	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	Chor_lyase
YHH2_k127_1718315_5	395494.Galf_2652	3.226e-44	162.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,44V3B@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YHH2_k127_1718315_0	580332.Slit_0311	1.736e-272	849.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,44V3B@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YHH2_k127_1718315_1	323848.Nmul_A2184	1.986e-161	517.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VHG5@28216|Betaproteobacteria,371Q8@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
YHH2_k127_1718315_11	1118153.MOY_05591	1.206e-07	56.0	COG3311@1|root,COG3311@2|Bacteria,1QNP5@1224|Proteobacteria,1SI1F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Phage transcriptional regulator AlpA	-	-	-	-	-	-	-	-	-	-	-	-	Phage_AlpA
YHH2_k127_1718315_9	644968.DFW101_0912	1.221e-08	61.0	2DR34@1|root,339YW@2|Bacteria,1NMQA@1224|Proteobacteria,436ZC@68525|delta/epsilon subdivisions,2X1PU@28221|Deltaproteobacteria,2MFFH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_39
YHH2_k127_1718315_3	1163617.SCD_n01191	2.926e-89	302.0	2C550@1|root,32RF3@2|Bacteria,1QFTU@1224|Proteobacteria,2VT94@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Plasmid recombination enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
YHH2_k127_1718315_10	153948.NAL212_1886	2.883e-08	59.0	2ER5V@1|root,33IRF@2|Bacteria,1NP0W@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1718315_7	2342.SOPEG_0598	1.737e-28	121.0	COG2369@1|root,COG2369@2|Bacteria,1NYZM@1224|Proteobacteria,1S0WW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Phage Mu protein F like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
YHH2_k127_1718315_8	1007105.PT7_1881	8.344e-24	106.0	2AHNH@1|root,3180G@2|Bacteria,1PZKN@1224|Proteobacteria,2W40I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
YHH2_k127_1718315_4	667632.KB890217_gene4920	1.66e-44	166.0	COG2944@1|root,COG2944@2|Bacteria,1N75U@1224|Proteobacteria,2VUMV@28216|Betaproteobacteria,1KDD2@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH2_k127_1718315_2	765911.Thivi_1814	3.157e-151	492.0	COG5433@1|root,COG5433@2|Bacteria,1MY25@1224|Proteobacteria,1RMRM@1236|Gammaproteobacteria,1WZJU@135613|Chromatiales	135613|Chromatiales	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
YHH2_k127_1724574_2	580332.Slit_1760	4.901e-80	269.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,44VTI@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YHH2_k127_1724574_0	580332.Slit_1765	0.0	1228.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,44VCB@713636|Nitrosomonadales	28216|Betaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH2_k127_1724574_9	765912.Thimo_1662	1.802e-21	95.0	2C1SS@1|root,32YN6@2|Bacteria,1NNFV@1224|Proteobacteria,1SS40@1236|Gammaproteobacteria,1X173@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1724574_10	1173029.JH980292_gene318	1.564e-17	85.0	2E90H@1|root,3339X@2|Bacteria,1G9EW@1117|Cyanobacteria,1HDD6@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1724574_11	504472.Slin_1329	3.766e-15	78.0	COG1396@1|root,COG1396@2|Bacteria,4PBTH@976|Bacteroidetes,47WAR@768503|Cytophagia	976|Bacteroidetes	K	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH2_k127_1724574_6	387093.SUN_1216	1.91e-29	126.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
YHH2_k127_1724574_4	1485545.JQLW01000007_gene758	3.166e-63	219.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria	1224|Proteobacteria	D	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	2.3.1.30	ko:K00640,ko:K07062	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000,ko02048	-	-	-	PIN
YHH2_k127_1724574_7	296591.Bpro_0012	1.222e-26	110.0	COG2161@1|root,COG2161@2|Bacteria,1NBSZ@1224|Proteobacteria,2WHF4@28216|Betaproteobacteria,4AFWB@80864|Comamonadaceae	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_1724574_1	580332.Slit_1773	3.278e-163	521.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2VMGT@28216|Betaproteobacteria	28216|Betaproteobacteria	GK	ROK family	nagK	-	2.7.1.2,2.7.1.4,2.7.1.59	ko:K00845,ko:K00847,ko:K00884	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01201,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH2_k127_1724574_3	748247.AZKH_p0114	2.479e-66	229.0	COG0346@1|root,COG0346@2|Bacteria,1N3A9@1224|Proteobacteria,2W2MH@28216|Betaproteobacteria,2KYUS@206389|Rhodocyclales	206389|Rhodocyclales	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YHH2_k127_1724574_5	614083.AWQR01000009_gene530	2.704e-32	128.0	COG5460@1|root,COG5460@2|Bacteria,1PTUZ@1224|Proteobacteria,2VV0Z@28216|Betaproteobacteria,4AF9I@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
YHH2_k127_1724574_8	1249627.D779_2121	4.012e-23	100.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria,1WXG1@135613|Chromatiales	135613|Chromatiales	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
YHH2_k127_1746172_11	555779.Dthio_PD3529	3.535e-52	190.0	28SSJ@1|root,2ZF2C@2|Bacteria,1RBGE@1224|Proteobacteria,430BQ@68525|delta/epsilon subdivisions,2WVPK@28221|Deltaproteobacteria,2MDI2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442,HTH_31
YHH2_k127_1746172_16	395493.BegalDRAFT_0692	3.987e-24	117.0	COG1106@1|root,COG1106@2|Bacteria,1R53P@1224|Proteobacteria,1S07P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
YHH2_k127_1746172_13	1120999.JONM01000012_gene2285	2.616e-40	151.0	COG4456@1|root,COG4456@2|Bacteria,1N6Y0@1224|Proteobacteria,2VW4I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SpoVT AbrB domain protein	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_1746172_8	1454004.AW11_00989	1.076e-67	232.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,2VWH6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH2_k127_1746172_18	1348657.M622_06290	6.252e-20	91.0	COG5450@1|root,COG5450@2|Bacteria,1N75T@1224|Proteobacteria,2WIG9@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
YHH2_k127_1746172_12	1286093.C266_03143	3.265e-48	175.0	COG1487@1|root,COG1487@2|Bacteria,1MZZ9@1224|Proteobacteria,2VSN5@28216|Betaproteobacteria,1K8N5@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_1746172_3	580332.Slit_1757	4.424e-187	587.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2VI51@28216|Betaproteobacteria,44VCM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH2_k127_1746172_0	580332.Slit_1758	0.0	1237.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,44V30@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
YHH2_k127_1746172_1	580332.Slit_1759	0.0	1059.0	COG0729@1|root,COG0729@2|Bacteria,1QVQI@1224|Proteobacteria,2W0WR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1746172_14	1122599.AUGR01000013_gene792	1.715e-38	146.0	COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,1S90R@1236|Gammaproteobacteria,1XKTV@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF1304)	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
YHH2_k127_1746172_15	234267.Acid_0524	1.588e-36	147.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YHH2_k127_1746172_9	365044.Pnap_2689	1.49e-61	218.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,4AEXS@80864|Comamonadaceae	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_1746172_2	365044.Pnap_2688	1.604e-190	616.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,4ADJN@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_1746172_6	1123368.AUIS01000001_gene1878	1.029e-94	316.0	COG4849@1|root,COG4849@2|Bacteria,1RDHG@1224|Proteobacteria,1S125@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH2_k127_1746172_7	1123368.AUIS01000001_gene1879	1.521e-75	258.0	28W7P@1|root,2ZI89@2|Bacteria,1N2SJ@1224|Proteobacteria,1SA34@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1746172_4	261292.Nit79A3_0267	8.869e-156	496.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHC7@28216|Betaproteobacteria,374M1@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Integrase, catalytic core	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
YHH2_k127_1746172_17	261292.Nit79A3_3015	3.986e-22	97.0	COG2963@1|root,COG2963@2|Bacteria,1N37Z@1224|Proteobacteria,2VUMC@28216|Betaproteobacteria,373SJ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Transposase IS3 IS911	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
YHH2_k127_1746172_10	580332.Slit_2605	5.344e-54	196.0	2AHNE@1|root,3180D@2|Bacteria,1PZKK@1224|Proteobacteria,2W40G@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1746172_5	743299.Acife_2300	3.321e-154	497.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
YHH2_k127_1761163_1	1000565.METUNv1_02811	9.59e-32	137.0	COG4585@1|root,COG4585@2|Bacteria,1R1TC@1224|Proteobacteria,2VHUA@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA_3
YHH2_k127_1761163_0	1000565.METUNv1_02809	1.195e-78	270.0	COG2197@1|root,COG2197@2|Bacteria,1RGXD@1224|Proteobacteria,2WEGP@28216|Betaproteobacteria	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_1761163_2	1123261.AXDW01000016_gene3035	8.35e-07	50.0	COG2197@1|root,COG2197@2|Bacteria,1RGXD@1224|Proteobacteria,1S3QG@1236|Gammaproteobacteria,1X67A@135614|Xanthomonadales	135614|Xanthomonadales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_1772886_3	1485544.JQKP01000001_gene1322	4.245e-36	139.0	COG1733@1|root,COG1733@2|Bacteria,1QVH2@1224|Proteobacteria,2W49M@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
YHH2_k127_1772886_1	1123256.KB907940_gene199	5.976e-79	272.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,1T5N0@1236|Gammaproteobacteria,1XDFW@135614|Xanthomonadales	135614|Xanthomonadales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
YHH2_k127_1772886_2	443144.GM21_3644	5.329e-46	176.0	2ADWP@1|root,313NS@2|Bacteria,1RHEN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1772886_0	1485544.JQKP01000001_gene1324	3.341e-135	439.0	2C60N@1|root,33S2Z@2|Bacteria,1NSI8@1224|Proteobacteria,2W0QW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1789821_1	580332.Slit_1186	1.302e-81	274.0	COG0662@1|root,COG0662@2|Bacteria,1RHRM@1224|Proteobacteria,2VTBD@28216|Betaproteobacteria,44WHB@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1789821_0	580332.Slit_1185	3.507e-108	361.0	2A8H0@1|root,30XJ2@2|Bacteria,1REE0@1224|Proteobacteria,2W21U@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1812584_2	580332.Slit_2545	6.487e-250	777.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,44VGF@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH2_k127_1812584_1	395494.Galf_2378	0.0	1137.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,44VP7@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
YHH2_k127_1812584_4	580332.Slit_2543	1.9e-122	394.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,44UYM@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
YHH2_k127_1812584_11	580332.Slit_2542	1.406e-28	116.0	2E8PT@1|root,3330W@2|Bacteria,1N796@1224|Proteobacteria,2VVUA@28216|Betaproteobacteria,44W2D@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1812584_0	580332.Slit_2541	0.0	1494.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,44VED@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Orn Lys Arg decarboxylase major region	adi	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
YHH2_k127_1812584_10	1123368.AUIS01000003_gene1673	1.879e-30	123.0	COG1708@1|root,COG1708@2|Bacteria,1N7SN@1224|Proteobacteria,1T99G@1236|Gammaproteobacteria,2NE28@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH2_k127_1812584_8	1123368.AUIS01000003_gene1672	2.232e-66	231.0	29XXA@1|root,30JPU@2|Bacteria,1PRTA@1224|Proteobacteria,1T99W@1236|Gammaproteobacteria,2NE2M@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1812584_9	580332.Slit_2540	8.021e-59	206.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,44WID@713636|Nitrosomonadales	28216|Betaproteobacteria	J	SMART RNA-binding S4 domain protein	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
YHH2_k127_1812584_7	580332.Slit_2539	6.229e-79	266.0	COG0526@1|root,COG0526@2|Bacteria,1RHPC@1224|Proteobacteria,2VTSB@28216|Betaproteobacteria,44WEN@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
YHH2_k127_1812584_3	1304883.KI912532_gene2802	2.364e-176	560.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria,2KZWY@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_1812584_5	1163617.SCD_n01690	2.748e-112	368.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VKEW@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Pfam ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_1812584_6	1163617.SCD_n01689	2.142e-88	297.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YHH2_k127_1813188_14	580332.Slit_1536	1.493e-40	154.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,44VBK@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
YHH2_k127_1813188_7	580332.Slit_1535	3.25e-115	372.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,44VRC@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
YHH2_k127_1813188_6	580332.Slit_1534	2.287e-135	437.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,44VGR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
YHH2_k127_1813188_8	580332.Slit_1533	1.729e-104	345.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,2VRAS@28216|Betaproteobacteria,44VRZ@713636|Nitrosomonadales	28216|Betaproteobacteria	EH	Amino-transferase class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
YHH2_k127_1813188_0	580332.Slit_1532	2.624e-237	737.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,44V9T@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH2_k127_1813188_15	580332.Slit_1531	3.371e-37	141.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,44VYH@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
YHH2_k127_1813188_9	986075.CathTA2_1881	7.063e-84	285.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli	91061|Bacilli	IQ	reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
YHH2_k127_1813188_3	580332.Slit_1529	3.233e-178	560.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,44V99@713636|Nitrosomonadales	28216|Betaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K13935,ko:K15355	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
YHH2_k127_1813188_5	580332.Slit_1528	3.615e-173	546.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,44VNK@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
YHH2_k127_1813188_1	580332.Slit_1527	1.351e-193	608.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria,44VJN@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
YHH2_k127_1813188_16	580332.Slit_1526	2.116e-31	123.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,44W39@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
YHH2_k127_1813188_12	580332.Slit_1525	4.747e-54	195.0	COG1399@1|root,COG1399@2|Bacteria,1PIWK@1224|Proteobacteria,2W7FZ@28216|Betaproteobacteria,44VYP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
YHH2_k127_1813188_10	580332.Slit_1524	4.436e-81	274.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,44VRW@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Maf-like protein	yceF	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
YHH2_k127_1813188_11	580332.Slit_1523	5.897e-76	256.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VQR5@28216|Betaproteobacteria,44VXB@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
YHH2_k127_1813188_13	580332.Slit_2045	1.784e-45	165.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VW9W@28216|Betaproteobacteria,44WPG@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH2_k127_1813188_4	946483.Cenrod_1459	4.571e-178	571.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,2VJUV@28216|Betaproteobacteria,4AC86@80864|Comamonadaceae	28216|Betaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
YHH2_k127_1813188_2	1051985.l11_00210	6.904e-180	575.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2VH6A@28216|Betaproteobacteria,2KPEY@206351|Neisseriales	206351|Neisseriales	K	Tex-like protein N-terminal domain protein	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
YHH2_k127_1813987_8	580332.Slit_2208	6.962e-102	336.0	COG2230@1|root,COG2230@2|Bacteria,1QXKQ@1224|Proteobacteria,2WHPJ@28216|Betaproteobacteria,44VP5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH2_k127_1813987_6	395494.Galf_1818	1.151e-159	507.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,2VSSE@28216|Betaproteobacteria,44V9Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
YHH2_k127_1813987_13	1173264.KI913949_gene1512	5.552e-40	151.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH2_k127_1813987_0	580332.Slit_2217	7.432e-295	908.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2VHR6@28216|Betaproteobacteria,44VFM@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Threonine synthase N terminus	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
YHH2_k127_1813987_1	580332.Slit_2218	5.41e-264	815.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,44V4Q@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
YHH2_k127_1813987_2	580332.Slit_2219	1.828e-257	796.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,44V1P@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_1813987_12	580332.Slit_2220	2.572e-54	195.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,44VYU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
YHH2_k127_1813987_5	580332.Slit_2221	1.729e-179	564.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,44WCC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ATPase associated with various cellular activities AAA_3	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YHH2_k127_1813987_14	472759.Nhal_3915	9.311e-29	117.0	COG1598@1|root,COG1598@2|Bacteria,1P4UT@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1813987_15	459495.SPLC1_S082950	2.207e-21	96.0	COG1724@1|root,COG1724@2|Bacteria,1G9XY@1117|Cyanobacteria,1HGG1@1150|Oscillatoriales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_1813987_9	395494.Galf_1460	1.208e-76	269.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,44WJ7@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SMART Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
YHH2_k127_1813987_7	1304883.KI912532_gene1609	3.872e-138	449.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,2KVRV@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
YHH2_k127_1813987_3	946483.Cenrod_0695	4.358e-202	664.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,4AA9F@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg
YHH2_k127_1813987_10	580332.Slit_2678	7.281e-76	257.0	COG2703@1|root,COG2703@2|Bacteria,1RK9A@1224|Proteobacteria,2VT8G@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
YHH2_k127_1813987_11	365044.Pnap_2689	2.734e-59	214.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,4AEXS@80864|Comamonadaceae	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_1813987_4	365044.Pnap_2688	3.892e-190	610.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,4ADJN@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_1826125_0	1198452.Jab_1c09850	1.056e-105	355.0	COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,2VNFR@28216|Betaproteobacteria,477I1@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
YHH2_k127_1826125_2	359.CN09_22240	3.887e-28	116.0	COG2002@1|root,COG2002@2|Bacteria,1N6CZ@1224|Proteobacteria,2UEUC@28211|Alphaproteobacteria,4BG3S@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1826125_1	311403.Arad_10006	9.139e-56	198.0	COG5611@1|root,COG5611@2|Bacteria,1RIZW@1224|Proteobacteria,2UA5E@28211|Alphaproteobacteria,4BGHV@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_1826125_3	395494.Galf_1993	9.981e-21	95.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,2VXC1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
YHH2_k127_1850498_2	580332.Slit_2064	2.691e-217	677.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,44V48@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC2	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_1850498_3	580332.Slit_2063	3.302e-196	614.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,2VH85@28216|Betaproteobacteria,44VHR@713636|Nitrosomonadales	28216|Betaproteobacteria	E	NeuB family	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
YHH2_k127_1850498_6	232348.ADXL01000091_gene464	1.001e-27	117.0	COG3577@1|root,COG3577@2|Bacteria,1G6TW@1117|Cyanobacteria	1117|Cyanobacteria	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas
YHH2_k127_1850498_8	765912.Thimo_3641	2.955e-18	91.0	COG0515@1|root,COG0515@2|Bacteria,1N79H@1224|Proteobacteria,1S6V2@1236|Gammaproteobacteria,1WZ9U@135613|Chromatiales	135613|Chromatiales	KLT	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
YHH2_k127_1850498_9	631362.Thi970DRAFT_04723	5.561e-17	83.0	2DECT@1|root,2ZMF9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1850498_7	631362.Thi970DRAFT_00193	2.2e-21	96.0	2E7RX@1|root,33276@2|Bacteria,1P206@1224|Proteobacteria,1SSHR@1236|Gammaproteobacteria	2|Bacteria	S	PFAM Uncharacterised protein family UPF0175	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
YHH2_k127_1850498_4	395494.Galf_1144	9.114e-143	457.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,44VG3@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
YHH2_k127_1850498_1	580332.Slit_2061	0.0	1064.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,44VC3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
YHH2_k127_1850498_0	580332.Slit_2060	0.0	1079.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,44V1X@713636|Nitrosomonadales	28216|Betaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
YHH2_k127_1850498_5	580332.Slit_2059	3.488e-52	184.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,44VZM@713636|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH2_k127_186701_4	580332.Slit_1516	1.136e-109	361.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2VMNV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
YHH2_k127_186701_8	1254432.SCE1572_01215	1.059e-40	155.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_186701_5	580332.Slit_1515	3.217e-107	352.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LemA Family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
YHH2_k127_186701_2	1304883.KI912532_gene2804	1.036e-124	404.0	COG3005@1|root,COG3005@2|Bacteria,1QZ6I@1224|Proteobacteria,2VPS8@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
YHH2_k127_186701_6	1304883.KI912532_gene2805	1.558e-98	323.0	COG1142@1|root,COG1142@2|Bacteria,1PPAS@1224|Proteobacteria,2W9FZ@28216|Betaproteobacteria,2KZD0@206389|Rhodocyclales	206389|Rhodocyclales	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_186701_1	395494.Galf_0844	3.095e-194	615.0	COG1018@1|root,COG1018@2|Bacteria,1MV41@1224|Proteobacteria,2VIIV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress	hmp	-	1.14.12.17	ko:K05916,ko:K07006,ko:K21832	ko05132,map05132	-	-	-	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,Globin,NAD_binding_1
YHH2_k127_186701_0	580332.Slit_1514	2.681e-214	670.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VH8N@28216|Betaproteobacteria,44V3E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
YHH2_k127_186701_3	580332.Slit_1512	2.824e-123	397.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,44V0V@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
YHH2_k127_186701_7	1485544.JQKP01000001_gene1237	4.947e-77	259.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2VR4W@28216|Betaproteobacteria,44VTC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
YHH2_k127_186701_9	580332.Slit_1510	7.674e-08	53.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,44VMR@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH2_k127_1936033_8	580332.Slit_2605	9.657e-65	227.0	2AHNE@1|root,3180D@2|Bacteria,1PZKK@1224|Proteobacteria,2W40G@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1936033_7	580332.Slit_2606	1.919e-67	237.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02457,ko:K02458,ko:K10930,ko:K12285	ko03070,ko05110,ko05111,map03070,map05110,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
YHH2_k127_1936033_2	580332.Slit_2607	2.398e-211	662.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VJ2Y@28216|Betaproteobacteria,44VCJ@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM Type II secretion system F domain	pilC3	-	-	ko:K02455,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
YHH2_k127_1936033_0	580332.Slit_2608	0.0	1000.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44V8J@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH2_k127_1936033_5	1485544.JQKP01000002_gene1553	2.399e-79	267.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,44VUM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
YHH2_k127_1936033_3	580332.Slit_2610	9.466e-158	503.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,44VMG@713636|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
YHH2_k127_1936033_9	580332.Slit_2611	5.511e-53	191.0	COG3807@1|root,COG3807@2|Bacteria,1MZIA@1224|Proteobacteria,2VUTD@28216|Betaproteobacteria,44W2W@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
YHH2_k127_1936033_6	580332.Slit_2612	1.467e-70	241.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,44VTN@713636|Nitrosomonadales	28216|Betaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
YHH2_k127_1936033_10	1198452.Jab_1c05430	5.295e-33	131.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,474TH@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
YHH2_k127_1936033_11	1123368.AUIS01000003_gene1732	1.005e-31	128.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,2NCVA@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH2_k127_1936033_1	580332.Slit_2615	3.934e-254	796.0	COG3307@1|root,COG3307@2|Bacteria,1RA1F@1224|Proteobacteria,2VQ8F@28216|Betaproteobacteria,44V2K@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Virulence factor membrane-bound polymerase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PglL_A,Wzy_C,Wzy_C_2
YHH2_k127_1936033_12	580332.Slit_2616	3.357e-31	123.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,2VVV9@28216|Betaproteobacteria,44W1A@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
YHH2_k127_1936033_4	580332.Slit_2617	3.077e-102	334.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,44VJ0@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH2_k127_2046249_2	395494.Galf_0139	1.13e-222	696.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria,44VER@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
YHH2_k127_2046249_14	580332.Slit_2929	1.944e-56	202.0	COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Pfam Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
YHH2_k127_2046249_5	580332.Slit_2928	9.645e-136	434.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,44VA6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
YHH2_k127_2046249_9	395494.Galf_2903	1.802e-84	286.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2VQ14@28216|Betaproteobacteria,44VQS@713636|Nitrosomonadales	28216|Betaproteobacteria	J	RNA pseudouridylate synthase	rluA	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
YHH2_k127_2046249_7	580332.Slit_2975	7.368e-117	382.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,2VNS7@28216|Betaproteobacteria,44VJS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM import inner membrane translocase subunit Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
YHH2_k127_2046249_0	580332.Slit_2976	8.326e-276	854.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,44V6Y@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
YHH2_k127_2046249_18	1499967.BAYZ01000157_gene592	4.14e-17	88.0	2DP2F@1|root,3308W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2046249_20	56110.Oscil6304_3587	5.478e-09	61.0	2DSKU@1|root,33GJ7@2|Bacteria,1GAWU@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2046249_12	580332.Slit_2822	2.362e-65	226.0	COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,2VVCK@28216|Betaproteobacteria,44WF3@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
YHH2_k127_2046249_6	580332.Slit_2821	1.646e-121	400.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,44V77@713636|Nitrosomonadales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
YHH2_k127_2046249_15	395494.Galf_2735	5.369e-56	196.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,44VZ4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
YHH2_k127_2046249_8	580332.Slit_2819	3.641e-112	366.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,44VV2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
YHH2_k127_2046249_3	580332.Slit_2818	2.124e-179	565.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,44VG9@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC transporter related	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
YHH2_k127_2046249_17	82654.Pse7367_0735	1.682e-25	114.0	COG0526@1|root,COG0526@2|Bacteria,1G9IM@1117|Cyanobacteria,1HD28@1150|Oscillatoriales	1117|Cyanobacteria	CO	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2046249_19	316055.RPE_2449	3.566e-11	72.0	2FEUJ@1|root,346TH@2|Bacteria,1P2KA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2046249_10	580332.Slit_2817	2.828e-80	269.0	COG0824@1|root,COG0824@2|Bacteria,1RCSP@1224|Proteobacteria,2VXA8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
YHH2_k127_2046249_4	580332.Slit_2816	1.263e-146	467.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,44W6T@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC-2 type transporter	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
YHH2_k127_2046249_11	580332.Slit_2815	2.228e-79	265.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,44VVU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
YHH2_k127_2046249_1	580332.Slit_2814	2.272e-230	715.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,44UYX@713636|Nitrosomonadales	28216|Betaproteobacteria	L	THUMP	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
YHH2_k127_2137684_8	658187.LDG_6897	0.000267	45.0	2B35H@1|root,31VTD@2|Bacteria,1RJF7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2137684_5	580332.Slit_2728	1.793e-79	267.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,44VXJ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
YHH2_k127_2137684_4	580332.Slit_2727	3.704e-164	521.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,44VNN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
YHH2_k127_2137684_6	580332.Slit_2726	1.962e-29	119.0	COG3116@1|root,COG3116@2|Bacteria,1N6WK@1224|Proteobacteria,2VW1W@28216|Betaproteobacteria,44W2Z@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
YHH2_k127_2137684_0	580332.Slit_2725	5.806e-285	888.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria,44VFB@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
YHH2_k127_2137684_1	580332.Slit_2724	3.166e-225	710.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,44VE4@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH2_k127_2137684_3	395494.Galf_0330	2.034e-175	565.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,44VA0@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10,6.3.2.13	ko:K01929,ko:K15792	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH2_k127_2137684_2	580332.Slit_2722	4.138e-213	670.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,44V5Q@713636|Nitrosomonadales	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
YHH2_k127_2137684_7	580332.Slit_2721	1.233e-09	61.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,44V6N@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH2_k127_2151609_6	395494.Galf_2653	6.804e-08	55.0	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,2VU5V@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	-	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	Chor_lyase
YHH2_k127_2151609_0	580332.Slit_0310	1.5e-162	514.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,44VQ9@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
YHH2_k127_2151609_3	580332.Slit_0305	2.348e-84	282.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,44VQR@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ferritin-like domain	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
YHH2_k127_2151609_5	395494.Galf_2387	5.668e-27	110.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rubA1	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
YHH2_k127_2151609_4	395494.Galf_2388	1.036e-76	259.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2VQ31@28216|Betaproteobacteria,44WN8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Rubrerythrin	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YHH2_k127_2151609_1	580332.Slit_0301	1.61e-162	515.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria,44WDP@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
YHH2_k127_2151609_2	580332.Slit_0300	2.977e-90	300.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2VSGQ@28216|Betaproteobacteria,44VSW@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH2_k127_2164288_1	580332.Slit_1426	5.822e-273	841.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,44VE3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
YHH2_k127_2164288_4	580332.Slit_1425	4.333e-208	651.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,44V4A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
YHH2_k127_2164288_13	580332.Slit_1424	4.061e-24	102.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria,44WN4@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
YHH2_k127_2164288_7	580332.Slit_1423	2.703e-155	493.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,44VKJ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
YHH2_k127_2164288_5	580332.Slit_1422	1.712e-204	641.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,44VCI@713636|Nitrosomonadales	28216|Betaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
YHH2_k127_2164288_3	580332.Slit_1421	8.922e-222	692.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria,44V2X@713636|Nitrosomonadales	28216|Betaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YHH2_k127_2164288_9	580332.Slit_1420	4.957e-39	147.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,44VYC@713636|Nitrosomonadales	28216|Betaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
YHH2_k127_2164288_14	640081.Dsui_0493	4.576e-16	87.0	2EFF1@1|root,3397W@2|Bacteria,1N9PW@1224|Proteobacteria,2VX4Q@28216|Betaproteobacteria,2KXE8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2164288_0	580332.Slit_1418	1.35e-285	881.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,44V5G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
YHH2_k127_2164288_6	580332.Slit_1417	1.446e-190	600.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,44VFV@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
YHH2_k127_2164288_8	580332.Slit_1416	6.514e-100	329.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,44VUI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
YHH2_k127_2164288_2	580332.Slit_1415	2.546e-243	755.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,44VJ4@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YHH2_k127_2164288_12	305700.B447_21000	4.236e-28	115.0	2E6XA@1|root,331GQ@2|Bacteria,1N9RM@1224|Proteobacteria,2VX2J@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
YHH2_k127_2164288_10	153948.NAL212_0060	7.201e-35	135.0	COG2944@1|root,COG2944@2|Bacteria,1PT1K@1224|Proteobacteria,2WAD4@28216|Betaproteobacteria,374HD@32003|Nitrosomonadales	28216|Betaproteobacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	-
YHH2_k127_2164288_11	32057.KB217472_gene7859	3.683e-34	135.0	COG4737@1|root,COG4737@2|Bacteria,1GEE5@1117|Cyanobacteria,1HST2@1161|Nostocales	1117|Cyanobacteria	S	RelE toxin of RelE / RelB toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
YHH2_k127_2164288_15	1038922.PflQ2_4000	7.942e-09	59.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,1RRFT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH2_k127_2166074_15	580332.Slit_2845	1.324e-58	206.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria,44WKZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
YHH2_k127_2166074_8	580332.Slit_2846	3.762e-168	531.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,44VEV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Phosphoribulokinase / Uridine kinase family	cbbP	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
YHH2_k127_2166074_16	640081.Dsui_1225	4.514e-56	207.0	COG4254@1|root,COG4254@2|Bacteria,1MYBD@1224|Proteobacteria,2VSSC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	FecR,SPOR
YHH2_k127_2166074_0	1485544.JQKP01000002_gene1453	0.0	1458.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,44V3Z@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
YHH2_k127_2166074_14	580332.Slit_2848	1.774e-60	216.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,44VZ0@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
YHH2_k127_2166074_7	580332.Slit_2849	4.606e-179	565.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria,44VB7@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
YHH2_k127_2166074_17	580332.Slit_2850	6.435e-48	174.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,44VZ7@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
YHH2_k127_2166074_2	580332.Slit_2851	8.25e-297	926.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,44VF5@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
YHH2_k127_2166074_12	580332.Slit_2853	2.796e-73	253.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,44VUG@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
YHH2_k127_2166074_13	580332.Slit_2854	1.002e-68	235.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,44VSU@713636|Nitrosomonadales	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
YHH2_k127_2166074_3	580332.Slit_2856	8.645e-292	899.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,44VMS@713636|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM Carbamoyl-phosphate synthase L chain ATP-binding	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YHH2_k127_2166074_9	580332.Slit_2857	4.361e-165	522.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2VH76@28216|Betaproteobacteria,44V4S@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
YHH2_k127_2166074_10	580332.Slit_2858	2.524e-85	293.0	2A4J7@1|root,30T5U@2|Bacteria,1RGAU@1224|Proteobacteria,2VU2M@28216|Betaproteobacteria,44W3F@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
YHH2_k127_2166074_19	28229.ND2E_0949	1.313e-31	126.0	COG4859@1|root,COG4859@2|Bacteria,1N30M@1224|Proteobacteria,1T09Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2185
YHH2_k127_2166074_11	580332.Slit_2921	7.898e-80	267.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VR3P@28216|Betaproteobacteria,44VYE@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH2_k127_2166074_5	580332.Slit_2922	2.142e-214	673.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria,44V0Z@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD1	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
YHH2_k127_2166074_1	580332.Slit_2923	1.622e-306	940.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,44V72@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Glutamine synthetase, catalytic domain	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YHH2_k127_2166074_18	580332.Slit_2924	2.504e-40	154.0	2ADYZ@1|root,313R9@2|Bacteria,1Q78X@1224|Proteobacteria,2WABJ@28216|Betaproteobacteria,44WNK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
YHH2_k127_2166074_6	580332.Slit_2925	9.853e-189	593.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,44VKA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART ATP-binding region ATPase domain protein	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
YHH2_k127_2166074_4	580332.Slit_2926	3.959e-270	835.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,44V04@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Nitrogen metabolism transcriptional regulator, NtrC, Fis Family	ntrC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_2170759_10	314345.SPV1_02322	3.036e-19	94.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria	1224|Proteobacteria	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
YHH2_k127_2170759_9	1242969.ATCC51562_1024	2.412e-21	96.0	COG2026@1|root,COG2026@2|Bacteria,1MZ76@1224|Proteobacteria,42TVA@68525|delta/epsilon subdivisions,2YQ4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	DJ	ParE-like toxin of type II bacterial toxin-antitoxin system	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
YHH2_k127_2170759_7	580332.Slit_1772	7.379e-44	160.0	COG2161@1|root,COG2161@2|Bacteria,1N6YR@1224|Proteobacteria,2VU62@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K18923	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
YHH2_k127_2170759_12	1249480.B649_09485	1.614e-07	58.0	COG3076@1|root,COG3076@2|Bacteria,1N195@1224|Proteobacteria,42YI2@68525|delta/epsilon subdivisions,2YRF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Family of unknown function (DUF695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF695,RraB
YHH2_k127_2170759_13	1082933.MEA186_21596	4.167e-05	49.0	2DRQ5@1|root,33CJP@2|Bacteria,1NC87@1224|Proteobacteria,2VG4E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cysteine rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_FGFR
YHH2_k127_2170759_2	1123073.KB899241_gene1791	4.593e-176	580.0	COG3055@1|root,COG3170@1|root,COG4625@1|root,COG3055@2|Bacteria,COG3170@2|Bacteria,COG4625@2|Bacteria,1R9K3@1224|Proteobacteria,1S1R4@1236|Gammaproteobacteria,1X91T@135614|Xanthomonadales	135614|Xanthomonadales	NU	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_6
YHH2_k127_2170759_0	1485544.JQKP01000020_gene61	8.845e-262	826.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKYE@28216|Betaproteobacteria,44W7M@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
YHH2_k127_2170759_6	398767.Glov_3520	6.77e-62	241.0	COG3614@1|root,COG3852@1|root,COG4251@1|root,COG3614@2|Bacteria,COG3852@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,dCache_1
YHH2_k127_2170759_4	1121035.AUCH01000003_gene1219	5.992e-87	318.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,2KUH6@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	2.7.13.3	ko:K20975	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_2170759_1	580332.Slit_0483	6.276e-200	631.0	COG0642@1|root,COG2205@2|Bacteria,1PFQP@1224|Proteobacteria,2W8ZK@28216|Betaproteobacteria,44WJR@713636|Nitrosomonadales	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
YHH2_k127_2170759_3	580332.Slit_0484	1.34e-128	415.0	COG0745@1|root,COG0745@2|Bacteria,1PFQS@1224|Proteobacteria,2W982@28216|Betaproteobacteria,44WHJ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483,ko:K07662	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_2170759_8	580332.Slit_0485	1.434e-39	152.0	2DG9F@1|root,32U6V@2|Bacteria,1N0HX@1224|Proteobacteria,2VTXA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LTXXQ motif family protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
YHH2_k127_2170759_5	1100721.ALKO01000017_gene1676	3.814e-84	285.0	2AINN@1|root,31954@2|Bacteria,1NDHA@1224|Proteobacteria,2W5W6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
YHH2_k127_2170759_11	1366050.N234_23560	2.435e-12	74.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VJ1B@28216|Betaproteobacteria,1K3EN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH2_k127_2177008_1	580332.Slit_2362	1.321e-124	406.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,44VE9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
YHH2_k127_2177008_0	580332.Slit_2361	1.359e-186	593.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,2VMDE@28216|Betaproteobacteria,44VJT@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
YHH2_k127_2177008_2	580332.Slit_2360	9.917e-96	321.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,2VRRA@28216|Betaproteobacteria,44VS9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
YHH2_k127_221499_0	1000565.METUNv1_02810	2.855e-132	433.0	2FFQC@1|root,347MN@2|Bacteria,1P3GT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_221499_1	358220.C380_06710	2.459e-98	333.0	COG4585@1|root,COG4585@2|Bacteria,1R8DN@1224|Proteobacteria,2VPJ9@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
YHH2_k127_2226276_0	118173.KB235914_gene4228	1.06e-27	117.0	COG5611@1|root,COG5611@2|Bacteria,1G7DU@1117|Cyanobacteria,1HBQA@1150|Oscillatoriales	2|Bacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_2226276_1	686340.Metal_1699	3.421e-05	49.0	COG2002@1|root,COG2002@2|Bacteria,1N5YP@1224|Proteobacteria,1SBID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	TIGRFAM looped-hinge helix DNA binding domain, AbrB family	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
YHH2_k127_2263615_2	153948.NAL212_2404	7.208e-18	85.0	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,2VKSJ@28216|Betaproteobacteria,373Q7@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Transposase, IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
YHH2_k127_2263615_3	879212.DespoDRAFT_02754	1.59e-11	68.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42TZ6@68525|delta/epsilon subdivisions,2WQY3@28221|Deltaproteobacteria,2MN04@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
YHH2_k127_2263615_0	1397528.Q671_06095	1.924e-190	603.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1XR29@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
YHH2_k127_2263615_1	522306.CAP2UW1_0092	5.806e-99	331.0	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,2VKSJ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Pfam Transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
YHH2_k127_2263615_4	261292.Nit79A3_2501	2.138e-11	66.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHC7@28216|Betaproteobacteria,374M1@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Integrase, catalytic core	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
YHH2_k127_2313247_1	580332.Slit_0730	9.627e-208	654.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2VNY1@28216|Betaproteobacteria,44V9Q@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	regB	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
YHH2_k127_2313247_10	326297.Sama_0272	4.111e-20	105.0	COG5184@1|root,COG5184@2|Bacteria,1N6X9@1224|Proteobacteria	1224|Proteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2313247_6	398578.Daci_2893	2.297e-42	175.0	29SNW@1|root,30DUI@2|Bacteria,1RDGS@1224|Proteobacteria,2VNTQ@28216|Betaproteobacteria,4AH23@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2313247_3	136993.KB900626_gene1391	4.17e-125	412.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TRTJ@28211|Alphaproteobacteria,36Z8P@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
YHH2_k127_2313247_8	265072.Mfla_2194	1.973e-32	143.0	2DQRB@1|root,3388D@2|Bacteria,1N385@1224|Proteobacteria,2VTXH@28216|Betaproteobacteria,2KNNM@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2313247_9	580332.Slit_1469	3.718e-22	111.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,2VHDJ@28216|Betaproteobacteria	28216|Betaproteobacteria	MU	TIGRFAM outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,He_PIG,TIG
YHH2_k127_2313247_0	1163617.SCD_n02539	6.739e-258	817.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB-dependent copper receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH2_k127_2313247_7	580332.Slit_0732	1.154e-34	138.0	COG2847@1|root,COG2847@2|Bacteria,1PWY4@1224|Proteobacteria,2WCG0@28216|Betaproteobacteria,44W0E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
YHH2_k127_2313247_2	580332.Slit_0735	3.128e-177	556.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria,44V2H@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
YHH2_k127_2313247_4	580332.Slit_0736	1.728e-121	391.0	COG0637@1|root,COG0637@2|Bacteria,1QTWD@1224|Proteobacteria,2VNTW@28216|Betaproteobacteria,44UZ1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
YHH2_k127_2313247_5	580332.Slit_0737	2.229e-71	247.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,44WBD@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	slmA	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
YHH2_k127_2358469_3	1538295.JY96_05450	1.68e-94	323.0	COG2984@1|root,COG2984@2|Bacteria,1REID@1224|Proteobacteria,2VZBZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
YHH2_k127_2358469_0	697282.Mettu_3159	6.677e-211	682.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XE5X@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
YHH2_k127_2358469_1	580332.Slit_1287	1.006e-207	649.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,44V3T@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	2.7.8.7,3.2.1.52	ko:K00997,ko:K01207	ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501	M00628	R00022,R01625,R05963,R07809,R07810,R10831	RC00002,RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
YHH2_k127_2358469_2	580332.Slit_1291	4.928e-140	451.0	COG3115@1|root,COG3115@2|Bacteria,1NJ6D@1224|Proteobacteria,2VHQ7@28216|Betaproteobacteria,44VC1@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	-	-	-	-	-	-	-	-	-	ZipA_C
YHH2_k127_2371958_3	580332.Slit_2979	1.288e-92	308.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,44V20@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
YHH2_k127_2371958_4	580332.Slit_2980	2.8e-70	239.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,44VV1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
YHH2_k127_2371958_1	580332.Slit_2981	1.271e-291	897.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,44V86@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH2_k127_2371958_2	580332.Slit_2982	5.311e-163	515.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,44V00@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
YHH2_k127_2371958_0	580332.Slit_2983	1.731e-312	960.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,44V6D@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
YHH2_k127_2371958_5	580332.Slit_2984	5.609e-16	77.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,44VX0@713636|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
YHH2_k127_2390956_3	1123393.KB891317_gene2372	4.629e-17	80.0	COG1146@1|root,COG1146@2|Bacteria,1RC9N@1224|Proteobacteria,2W1W6@28216|Betaproteobacteria,1KSRH@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Adenosine-5'-phosphosulfate reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_9
YHH2_k127_2390956_0	396588.Tgr7_0353	1.344e-213	667.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1WWF2@135613|Chromatiales	135613|Chromatiales	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
YHH2_k127_2390956_1	1266925.JHVX01000001_gene2469	2.213e-99	329.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,2VKZ3@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_2390956_4	234267.Acid_2761	3.201e-10	68.0	COG1819@1|root,COG1819@2|Bacteria,3Y3H9@57723|Acidobacteria	2|Bacteria	CG	PFAM glycosyl transferase, family 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
YHH2_k127_2390956_2	930169.B5T_01767	1.467e-59	209.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,1RTDH@1236|Gammaproteobacteria,1XQQP@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2411602_0	580332.Slit_0729	2.988e-83	280.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2VN1I@28216|Betaproteobacteria,44VQ1@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
YHH2_k127_2411602_10	637390.AFOH01000045_gene2171	6.478e-23	101.0	COG4118@1|root,COG4118@2|Bacteria,1N9P1@1224|Proteobacteria,1SIEW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_2411602_4	946483.Cenrod_2417	1.298e-43	164.0	COG1848@1|root,COG1848@2|Bacteria,1MYDN@1224|Proteobacteria,2VTED@28216|Betaproteobacteria,4AHTA@80864|Comamonadaceae	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_2411602_12	768671.ThimaDRAFT_2874	2.837e-08	57.0	2CD0B@1|root,345WA@2|Bacteria,1P32Z@1224|Proteobacteria,1SRCX@1236|Gammaproteobacteria,1X1GN@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2411602_13	290317.Cpha266_2647	1.528e-07	55.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_2411602_15	385682.AFSL01000046_gene528	0.0002478	46.0	COG1487@1|root,COG1487@2|Bacteria,4NVG8@976|Bacteroidetes,2FYWW@200643|Bacteroidia,3XKED@558415|Marinilabiliaceae	976|Bacteroidetes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_2411602_5	717773.Thicy_0576	9.607e-42	157.0	COG4226@1|root,COG4226@2|Bacteria,1MZYR@1224|Proteobacteria,1SB6C@1236|Gammaproteobacteria,461D9@72273|Thiotrichales	72273|Thiotrichales	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
YHH2_k127_2411602_7	717772.THIAE_06700	7.536e-37	140.0	2CT64@1|root,32SSN@2|Bacteria,1N7H4@1224|Proteobacteria,1SEH7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_2411602_11	742735.HMPREF9467_00140	9.9e-18	85.0	2E9T0@1|root,333Z2@2|Bacteria,1VHPB@1239|Firmicutes,24SMK@186801|Clostridia	186801|Clostridia	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_2411602_6	102125.Xen7305DRAFT_00038860	1.57e-37	145.0	COG4226@1|root,COG4226@2|Bacteria,1GA9I@1117|Cyanobacteria,3VMSP@52604|Pleurocapsales	1117|Cyanobacteria	S	protein encoded in hypervariable junctions of pilus gene clusters	-	-	-	-	-	-	-	-	-	-	-	-	HicB
YHH2_k127_2411602_8	1122194.AUHU01000002_gene2936	3.637e-30	123.0	COG1487@1|root,COG1487@2|Bacteria,1N44Q@1224|Proteobacteria,1SD4I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_2411602_2	316067.Geob_3253	2.337e-51	204.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YHH2_k127_2411602_3	398767.Glov_0642	1.827e-45	186.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
YHH2_k127_2411602_1	1288826.MSNKSG1_16631	1.143e-58	214.0	COG0596@1|root,COG0596@2|Bacteria,1RGAP@1224|Proteobacteria,1S1M7@1236|Gammaproteobacteria,468DW@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE
YHH2_k127_2411602_9	305700.B447_09653	5.155e-23	110.0	COG2771@1|root,COG2771@2|Bacteria,1MWC0@1224|Proteobacteria,2VX3T@28216|Betaproteobacteria,2KZES@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2443178_1	582744.Msip34_0958	3.387e-40	156.0	COG4302@1|root,COG4302@2|Bacteria,1MWQI@1224|Proteobacteria,2VJ8Y@28216|Betaproteobacteria,2KNF8@206350|Nitrosomonadales	206350|Nitrosomonadales	H	PFAM Ethanolamine ammonia-lyase light chain	-	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
YHH2_k127_2443178_0	582744.Msip34_0957	2.728e-244	760.0	COG4303@1|root,COG4303@2|Bacteria,1MUR4@1224|Proteobacteria,2VIJW@28216|Betaproteobacteria,2KNEH@206350|Nitrosomonadales	206350|Nitrosomonadales	E	PFAM Ethanolamine ammonia lyase large subunit	-	-	4.3.1.7	ko:K03735	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutB
YHH2_k127_2443178_3	749222.Nitsa_1517	6.333e-10	65.0	2AJF0@1|root,31A1A@2|Bacteria,1Q4MS@1224|Proteobacteria,42ZG6@68525|delta/epsilon subdivisions,2YRPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2443178_4	1121381.JNIV01000058_gene1996	2.546e-06	58.0	COG0358@1|root,COG0358@2|Bacteria,1WIXS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_2,Toprim_4,Toprim_N,zf-CHC2
YHH2_k127_2443178_2	348824.LPU83_0667	1.766e-10	65.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,4BGUM@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
YHH2_k127_252391_2	926569.ANT_18610	1.121e-55	201.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	purD	-	-	-	-	-	-	-	-	-	-	-	DegV
YHH2_k127_252391_0	747365.Thena_0761	5.062e-101	341.0	COG2801@1|root,COG2801@2|Bacteria,1UINX@1239|Firmicutes,24BC3@186801|Clostridia	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH2_k127_252391_1	926569.ANT_13730	9.706e-78	265.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
YHH2_k127_2559236_16	580332.Slit_1259	4.586e-130	420.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,44WDQ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
YHH2_k127_2559236_23	1095769.CAHF01000005_gene1464	1.079e-47	179.0	2EDK5@1|root,337FY@2|Bacteria,1ND05@1224|Proteobacteria,2W4RU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2559236_18	519989.ECTPHS_09168	4.378e-126	411.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1WWM1@135613|Chromatiales	135613|Chromatiales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
YHH2_k127_2559236_4	204773.HEAR0489	6.072e-245	767.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria	28216|Betaproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YHH2_k127_2559236_3	472759.Nhal_2290	6.797e-246	780.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1WXXX@135613|Chromatiales	135613|Chromatiales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YHH2_k127_2559236_24	204773.HEAR0487	4.532e-44	167.0	2A49J@1|root,30SV1@2|Bacteria,1RF7U@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2559236_14	204773.HEAR0486	1.506e-149	479.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,2WCKW@28216|Betaproteobacteria,477VB@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
YHH2_k127_2559236_8	580332.Slit_1047	3.585e-200	625.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2VHCK@28216|Betaproteobacteria,44W96@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Winged helix-turn-helix transcription repressor, HrcA DNA-binding	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
YHH2_k127_2559236_10	580332.Slit_1046	6.541e-177	579.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,44VHG@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
YHH2_k127_2559236_17	1163617.SCD_n02351	1.686e-128	419.0	COG1819@1|root,COG1819@2|Bacteria,1MVJM@1224|Proteobacteria,2VME8@28216|Betaproteobacteria	28216|Betaproteobacteria	CG	glycosyl	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2559236_2	395494.Galf_2164	5.497e-252	788.0	COG2199@1|root,COG5000@1|root,COG2199@2|Bacteria,COG5000@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CHASE,CHASE8,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9
YHH2_k127_2559236_19	580332.Slit_1043	1.103e-104	341.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,44VDX@713636|Nitrosomonadales	28216|Betaproteobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
YHH2_k127_2559236_7	580332.Slit_1042	3.006e-216	677.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,44VFZ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
YHH2_k127_2559236_25	580332.Slit_1041	2.163e-41	155.0	COG3474@1|root,COG3474@2|Bacteria,1NIH9@1224|Proteobacteria,2WHPP@28216|Betaproteobacteria,44W35@713636|Nitrosomonadales	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YHH2_k127_2559236_21	580332.Slit_1040	5.376e-58	203.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria	28216|Betaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YHH2_k127_2559236_13	580332.Slit_1039	9.891e-161	509.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria,44UZ3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
YHH2_k127_2559236_27	357808.RoseRS_0548	6.441e-31	129.0	COG2361@1|root,COG2361@2|Bacteria,2G8W4@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
YHH2_k127_2559236_31	593750.Metfor_1253	7.969e-16	80.0	COG1669@1|root,arCOG01206@2157|Archaea,2Y02Z@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM DNA polymerase, beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
YHH2_k127_2559236_11	1485544.JQKP01000017_gene644	2.64e-173	553.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,44VDJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_2559236_0	580332.Slit_1835	0.0	1651.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,44VD6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	2-oxoglutarate dehydrogenase N-terminus	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
YHH2_k127_2559236_5	580332.Slit_1836	1.722e-240	747.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,44VKZ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
YHH2_k127_2559236_29	580332.Slit_1837	1.434e-27	114.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,2VY7W@28216|Betaproteobacteria,44W4H@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
YHH2_k127_2559236_15	580332.Slit_1838	2.407e-145	462.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,44VM4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
YHH2_k127_2559236_1	580332.Slit_1839	0.0	1151.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,44V9G@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH2_k127_2559236_26	323848.Nmul_A0862	1.7e-37	145.0	COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria,373DV@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
YHH2_k127_2559236_22	580332.Slit_1841	8.072e-58	204.0	COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VSEG@28216|Betaproteobacteria,44W0Z@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM succinate dehydrogenase, cytochrome b556 subunit	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
YHH2_k127_2559236_12	580332.Slit_1842	6.142e-171	541.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2VHC8@28216|Betaproteobacteria,44VIC@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
YHH2_k127_2559236_6	580332.Slit_2434	2.034e-232	725.0	COG1502@1|root,COG1502@2|Bacteria,1PFSH@1224|Proteobacteria,2VH6R@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2559236_20	1288494.EBAPG3_1710	8.315e-98	338.0	COG1195@1|root,COG1195@2|Bacteria	2|Bacteria	L	single-stranded DNA binding	smc	-	-	ko:K03529,ko:K07459	-	-	-	-	ko00000,ko03036	-	-	-	AAA_15,AAA_21,AAA_23,AAA_27,SMC_N,SMC_hinge
YHH2_k127_2559236_9	1028801.RG1141_CH23700	5.831e-197	634.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1PH57@1224|Proteobacteria,2VAS2@28211|Alphaproteobacteria,4BJY0@82115|Rhizobiaceae	28211|Alphaproteobacteria	V	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2559236_30	1331060.RLDS_11260	5.574e-18	83.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2697326_4	580332.Slit_0948	1.002e-36	141.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,44VXI@713636|Nitrosomonadales	28216|Betaproteobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
YHH2_k127_2697326_0	580332.Slit_0947	2.756e-261	809.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,44VAR@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
YHH2_k127_2697326_3	1028801.RG1141_PA01150	4.983e-37	140.0	2CT64@1|root,32SSN@2|Bacteria,1N7H4@1224|Proteobacteria,2UC1T@28211|Alphaproteobacteria,4BG2I@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	HicA toxin of bacterial toxin-antitoxin,	hicA	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_2697326_2	1433287.X808_5450	1.1e-38	147.0	COG4226@1|root,COG4226@2|Bacteria,1MZYR@1224|Proteobacteria,1SAHX@1236|Gammaproteobacteria,1Y97N@135625|Pasteurellales	135625|Pasteurellales	S	nuclease of the RNAse H fold, HicB family COG4226	hicB	-	-	-	-	-	-	-	-	-	-	-	HicB
YHH2_k127_2706652_1	598659.NAMH_1184	5.419e-12	66.0	2AY0S@1|root,31Q2B@2|Bacteria,1QMQY@1224|Proteobacteria,42SY0@68525|delta/epsilon subdivisions,2YPGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
YHH2_k127_2706652_2	580332.Slit_1773	0.0004509	46.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2VMGT@28216|Betaproteobacteria	28216|Betaproteobacteria	GK	ROK family	nagK	-	2.7.1.2,2.7.1.4,2.7.1.59	ko:K00845,ko:K00847,ko:K00884	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01201,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH2_k127_2706652_0	857087.Metme_1830	4.784e-160	530.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,1XGNR@135618|Methylococcales	135618|Methylococcales	P	PFAM Cation H exchanger	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
YHH2_k127_271625_3	443152.MDG893_16052	3.144e-41	153.0	COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1SABZ@1236|Gammaproteobacteria,46880@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	enzyme involved in biosynthesis of extracellular polysaccharides	yqjZ	-	-	-	-	-	-	-	-	-	-	-	ABM
YHH2_k127_271625_5	1122933.JNIY01000003_gene312	0.0002068	51.0	COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria,4F2D0@85016|Cellulomonadaceae	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH2_k127_271625_2	395494.Galf_0149	1.039e-91	309.0	COG3437@1|root,COG3437@2|Bacteria,1RJ22@1224|Proteobacteria,2VSV3@28216|Betaproteobacteria,44VV8@713636|Nitrosomonadales	28216|Betaproteobacteria	KT	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
YHH2_k127_271625_0	580332.Slit_0895	1.125e-111	365.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
YHH2_k127_271625_1	580332.Slit_0896	2.995e-95	318.0	COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1Q14J@1224|Proteobacteria,2W9SH@28216|Betaproteobacteria,44WFR@713636|Nitrosomonadales	28216|Betaproteobacteria	H	TOBE domain	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	TOBE
YHH2_k127_2763041_4	1348657.M622_01270	2.14e-36	143.0	COG3668@1|root,COG3668@2|Bacteria,1N9C2@1224|Proteobacteria,2VWK0@28216|Betaproteobacteria,2KXN9@206389|Rhodocyclales	206389|Rhodocyclales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_2763041_5	62928.azo3076	1.413e-31	125.0	COG3905@1|root,COG3905@2|Bacteria,1NB4C@1224|Proteobacteria,2WBWT@28216|Betaproteobacteria,2KZIY@206389|Rhodocyclales	206389|Rhodocyclales	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2763041_2	580332.Slit_2796	6.647e-127	412.0	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,2VSZR@28216|Betaproteobacteria,44WFM@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SEC-C motif domain protein	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
YHH2_k127_2763041_0	338969.Rfer_1397	2.825e-219	686.0	COG0025@1|root,COG0025@2|Bacteria,1QA7B@1224|Proteobacteria,2VHPR@28216|Betaproteobacteria,4ACQT@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YHH2_k127_2763041_3	156889.Mmc1_3073	7.772e-84	291.0	28HKZ@1|root,2Z7VP@2|Bacteria,1R4QW@1224|Proteobacteria,2U7WP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3050)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3050
YHH2_k127_2763041_1	580332.Slit_0134	6.44e-188	588.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,44VJ6@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH2_k127_276543_1	1163617.SCD_n02722	2.271e-66	229.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria	28216|Betaproteobacteria	P	sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
YHH2_k127_276543_2	1415630.U771_22424	5.617e-36	141.0	2AFID@1|root,3336Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_276543_0	580332.Slit_2399	1.431e-74	256.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,44WG0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cobalamin adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
YHH2_k127_276543_3	1485544.JQKP01000001_gene1047	3.861e-11	64.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,44VU7@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
YHH2_k127_2780570_5	658187.LDG_6897	2.856e-05	46.0	2B35H@1|root,31VTD@2|Bacteria,1RJF7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2780570_6	858619.CVAR_0541	3.763e-05	57.0	COG1075@1|root,COG1075@2|Bacteria,2GM7V@201174|Actinobacteria,22K9M@1653|Corynebacteriaceae	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	lip	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4,Lipase_2
YHH2_k127_2780570_4	443906.CMM_0825	3.825e-08	67.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
YHH2_k127_2780570_1	398767.Glov_2076	8.255e-57	226.0	COG0515@1|root,COG0515@2|Bacteria	398767.Glov_2076|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2780570_3	398767.Glov_2072	3.399e-34	153.0	COG0515@1|root,COG0515@2|Bacteria,1N79H@1224|Proteobacteria,42XTB@68525|delta/epsilon subdivisions,2WWHE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
YHH2_k127_2780570_2	580332.Slit_1485	5.833e-43	158.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,44VZI@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
YHH2_k127_2780570_0	580332.Slit_1486	0.0	1284.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,44V9N@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YHH2_k127_2876053_0	1485544.JQKP01000001_gene1063	4.329e-200	632.0	COG0515@1|root,COG4886@1|root,COG0515@2|Bacteria,COG4886@2|Bacteria,1Q94S@1224|Proteobacteria,2VIVY@28216|Betaproteobacteria,44W9I@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4,LRR_8,Pkinase,Pkinase_Tyr
YHH2_k127_2876053_1	580332.Slit_2158	3.939e-166	528.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,44V8T@713636|Nitrosomonadales	1224|Proteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
YHH2_k127_2926871_10	322710.Avin_24740	5.724e-05	46.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
YHH2_k127_2926871_4	1123257.AUFV01000003_gene859	1.59e-33	146.0	COG4585@1|root,COG4585@2|Bacteria,1R6FX@1224|Proteobacteria,1S0UD@1236|Gammaproteobacteria,1X45P@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
YHH2_k127_2926871_8	1236514.BAKL01000150_gene5751	1.389e-07	65.0	COG4447@1|root,COG4447@2|Bacteria,4NX71@976|Bacteroidetes,2FXP6@200643|Bacteroidia,4ATV2@815|Bacteroidaceae	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2926871_0	264730.PSPPH_A0052	3.904e-64	221.0	COG1569@1|root,COG1569@2|Bacteria,1RE43@1224|Proteobacteria,1S40R@1236|Gammaproteobacteria,1Z9XY@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
YHH2_k127_2926871_5	291112.PAU_02341	7.038e-32	126.0	2CEYG@1|root,32S0U@2|Bacteria,1N2NE@1224|Proteobacteria,1SAXV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ribbon-helix-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	RHH_6
YHH2_k127_2926871_7	1280390.CBQR020000166_gene4415	8.956e-10	72.0	COG3934@1|root,COG5297@1|root,COG3934@2|Bacteria,COG5297@2|Bacteria,1V19K@1239|Firmicutes,4IQ1F@91061|Bacilli,2765Y@186822|Paenibacillaceae	91061|Bacilli	G	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2926871_6	398767.Glov_2076	5.48e-25	122.0	COG0515@1|root,COG0515@2|Bacteria	398767.Glov_2076|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2926871_2	312153.Pnuc_0342	2.843e-43	160.0	COG4742@1|root,COG4742@2|Bacteria	2|Bacteria	K	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,HATPase_c,Methyltransf_2,Response_reg
YHH2_k127_2926871_3	312153.Pnuc_0341	9.552e-36	138.0	2E1B7@1|root,32WR3@2|Bacteria,1N4JM@1224|Proteobacteria,2VVF6@28216|Betaproteobacteria,1KEW5@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2926871_9	83406.HDN1F_17150	5.367e-06	48.0	COG1569@1|root,COG1569@2|Bacteria,1RE43@1224|Proteobacteria,1S40R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
YHH2_k127_2926871_1	316067.Geob_3253	2.236e-54	198.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YHH2_k127_2929042_11	395494.Galf_1887	1.781e-72	247.0	COG0454@1|root,COG0456@2|Bacteria,1N009@1224|Proteobacteria,2VQU1@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
YHH2_k127_2929042_14	395494.Galf_1886	7.659e-38	145.0	COG4453@1|root,COG4453@2|Bacteria,1NCEW@1224|Proteobacteria,2VW96@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
YHH2_k127_2929042_4	395494.Galf_2315	4.61e-163	522.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VI1J@28216|Betaproteobacteria,44VE0@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM Type II secretion system F domain	pilC2	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH2_k127_2929042_1	395494.Galf_2314	4.299e-250	784.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44VPC@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	General secretory system II protein E domain protein	xcpR	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH2_k127_2929042_13	395494.Galf_2313	5.695e-55	208.0	COG0457@1|root,COG0457@2|Bacteria,1RKBG@1224|Proteobacteria,2VQFW@28216|Betaproteobacteria,44W2M@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
YHH2_k127_2929042_3	395494.Galf_2312	6.235e-216	687.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMT1@28216|Betaproteobacteria,44V3S@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II and III secretion system protein	exeD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
YHH2_k127_2929042_8	395494.Galf_2311	1.033e-96	335.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2W9RR@28216|Betaproteobacteria,44WF1@713636|Nitrosomonadales	28216|Betaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
YHH2_k127_2929042_5	1485544.JQKP01000001_gene1099	1.537e-135	435.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,44VBC@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	ABC transporter	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YHH2_k127_2929042_6	1485544.JQKP01000001_gene1100	1.429e-131	423.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,44VFH@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Permease MlaE	ttg2B	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YHH2_k127_2929042_10	580332.Slit_0692	1.596e-74	252.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,44VUD@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
YHH2_k127_2929042_12	580332.Slit_0693	3.284e-69	241.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,44VY5@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	MlaC protein	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
YHH2_k127_2929042_18	1397528.Q671_07315	1.141e-06	55.0	COG1366@1|root,COG1366@2|Bacteria,1QTSG@1224|Proteobacteria,1SCUD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	factor (Antagonist	ttg2E	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
YHH2_k127_2929042_2	580332.Slit_0695	2.707e-239	744.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,44VFJ@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
YHH2_k127_2929042_17	1415780.JPOG01000001_gene713	7.11e-13	72.0	COG1708@1|root,COG1708@2|Bacteria,1N7SN@1224|Proteobacteria,1T5TY@1236|Gammaproteobacteria,1X92F@135614|Xanthomonadales	135614|Xanthomonadales	S	PFAM DNA polymerase, beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2929042_16	748658.KB907319_gene747	6.521e-20	98.0	2C4WJ@1|root,32Z4K@2|Bacteria,1MZU5@1224|Proteobacteria,1S6A8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2929042_7	580332.Slit_0696	1.201e-120	389.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria,44V3X@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
YHH2_k127_2929042_0	580332.Slit_0697	4.797e-255	789.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,44V4T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
YHH2_k127_2949370_3	1485544.JQKP01000001_gene1015	6.362e-58	203.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6N@1224|Proteobacteria,2VSXJ@28216|Betaproteobacteria,44WH4@713636|Nitrosomonadales	28216|Betaproteobacteria	K	HxlR-like helix-turn-helix	ytfH	-	-	-	-	-	-	-	-	-	-	-	HxlR
YHH2_k127_2949370_1	580332.Slit_2237	8.705e-137	440.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,2VM5Q@28216|Betaproteobacteria,44WCW@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
YHH2_k127_2949370_5	290315.Clim_0656	7.929e-45	164.0	COG4679@1|root,COG4679@2|Bacteria	2|Bacteria	K	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
YHH2_k127_2949370_7	331678.Cphamn1_1311	9.296e-35	134.0	COG3093@1|root,COG3093@2|Bacteria,1FFJY@1090|Chlorobi	1090|Chlorobi	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
YHH2_k127_2949370_2	1116472.MGMO_112c00130	3.967e-84	287.0	2DQ6U@1|root,3350B@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4393
YHH2_k127_2949370_10	580332.Slit_2233	1.349e-05	47.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,44UYD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
YHH2_k127_2949370_6	1454004.AW11_02028	5.505e-37	143.0	2DS2U@1|root,33E9F@2|Bacteria,1PAXB@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH2_k127_2949370_8	1454004.AW11_02027	1.976e-25	109.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	sohA	GO:0001558,GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040008,GO:0042802,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K19156	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin,PrlF_antitoxin
YHH2_k127_2949370_9	1197906.CAJQ02000027_gene1525	3.529e-06	51.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JV1X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH2_k127_2949370_0	580332.Slit_0799	6.833e-237	740.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,44V0W@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	yajR	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
YHH2_k127_2949370_4	395494.Galf_2423	3.65e-55	195.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,44VVD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YHH2_k127_2953770_3	1500890.JQNL01000001_gene2236	1.144e-08	58.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RR8F@1236|Gammaproteobacteria,1X4GJ@135614|Xanthomonadales	135614|Xanthomonadales	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
YHH2_k127_2953770_0	626418.bglu_1g20170	2.078e-44	162.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2VTZ8@28216|Betaproteobacteria,1K8WW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	similarity to SP P24580	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
YHH2_k127_2953770_1	886293.Sinac_1864	3.784e-42	175.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
YHH2_k127_2953770_2	1123392.AQWL01000002_gene1924	1.433e-27	113.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,1KRAX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
YHH2_k127_2955647_0	1441629.PCH70_14650	2.538e-98	358.0	2DN4D@1|root,32VFV@2|Bacteria,1N32J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2955647_1	580332.Slit_0463	1.358e-40	150.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,2VI7P@28216|Betaproteobacteria,44VGU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	S4 RNA-binding domain	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH2_k127_2999285_0	1266925.JHVX01000003_gene638	2.644e-306	944.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,372IS@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YHH2_k127_3045606_12	46681.XP_001738051.1	5.068e-11	69.0	2D8YH@1|root,2RBTH@2759|Eukaryota,3X9WR@554915|Amoebozoa	554915|Amoebozoa	G	peptidoglycan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3045606_2	1137799.GZ78_09680	2.924e-139	457.0	COG4942@1|root,COG4942@2|Bacteria,1MXRZ@1224|Proteobacteria,1RR9E@1236|Gammaproteobacteria,1XMXP@135619|Oceanospirillales	135619|Oceanospirillales	D	Protein of unknown function (DUF3375)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3375
YHH2_k127_3045606_6	1249627.D779_2080	4.271e-44	163.0	COG3514@1|root,COG3514@2|Bacteria,1QN0D@1224|Proteobacteria,1TKBW@1236|Gammaproteobacteria,1X1P1@135613|Chromatiales	135613|Chromatiales	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
YHH2_k127_3045606_11	699246.HMPREF0868_1060	1.872e-11	67.0	COG1502@1|root,COG1502@2|Bacteria,1TRJE@1239|Firmicutes,248ZE@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
YHH2_k127_3045606_8	317936.Nos7107_2981	3.401e-27	113.0	COG2929@1|root,COG2929@2|Bacteria,1G92M@1117|Cyanobacteria,1HSNE@1161|Nostocales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_3045606_10	686340.Metal_2588	1.57e-17	85.0	2C6B2@1|root,335GA@2|Bacteria,1NG8G@1224|Proteobacteria,1SHZ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3045606_5	760117.JN27_00255	1.578e-60	214.0	2CB46@1|root,31GHU@2|Bacteria,1NGIC@1224|Proteobacteria,2VQSQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
YHH2_k127_3045606_0	187272.Mlg_2294	0.0	1031.0	COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RPTX@1236|Gammaproteobacteria,1WVW9@135613|Chromatiales	135613|Chromatiales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
YHH2_k127_3045606_4	349124.Hhal_0740	3.49e-91	313.0	COG4924@1|root,COG4924@2|Bacteria,1P11B@1224|Proteobacteria,1RYWN@1236|Gammaproteobacteria,1WY8D@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria N-term (DUF3322)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220,DUF3322
YHH2_k127_3045606_13	686340.Metal_1699	3.612e-09	61.0	COG2002@1|root,COG2002@2|Bacteria,1N5YP@1224|Proteobacteria,1SBID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	TIGRFAM looped-hinge helix DNA binding domain, AbrB family	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
YHH2_k127_3045606_7	32049.SYNPCC7002_A0407	3.312e-29	121.0	COG5611@1|root,COG5611@2|Bacteria,1GFJ7@1117|Cyanobacteria,1H1RG@1129|Synechococcus	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_3045606_1	580332.Slit_1499	7.388e-297	915.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,44V4E@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM tRNA synthetase class II (D K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YHH2_k127_3045606_3	580332.Slit_1498	7.999e-111	361.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2VN3A@28216|Betaproteobacteria,44VNG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	nnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YHH2_k127_3045606_9	580332.Slit_2449	7.644e-18	83.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,44V8E@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
YHH2_k127_305199_0	580332.Slit_2413	0.0	1678.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,44V9P@713636|Nitrosomonadales	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
YHH2_k127_305199_1	580332.Slit_2411	4.681e-62	221.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,2VTYC@28216|Betaproteobacteria,44VZ8@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DNA polymerase III chi subunit HolC	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
YHH2_k127_3065436_1	582744.Msip34_0958	2.853e-86	291.0	COG4302@1|root,COG4302@2|Bacteria,1MWQI@1224|Proteobacteria,2VJ8Y@28216|Betaproteobacteria,2KNF8@206350|Nitrosomonadales	206350|Nitrosomonadales	H	PFAM Ethanolamine ammonia-lyase light chain	-	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
YHH2_k127_3065436_3	84531.JMTZ01000005_gene2415	3.549e-40	151.0	COG1917@1|root,COG1917@2|Bacteria,1MZNT@1224|Proteobacteria,1S8TU@1236|Gammaproteobacteria,1X90H@135614|Xanthomonadales	135614|Xanthomonadales	S	Cupin domain	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2
YHH2_k127_3065436_2	1005048.CFU_0883	1.094e-42	160.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,2VSVZ@28216|Betaproteobacteria,474BG@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	fdsG	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	2Fe-2S_thioredx
YHH2_k127_3065436_0	497321.C664_17707	5.771e-165	526.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VIGR@28216|Betaproteobacteria,2KXTE@206389|Rhodocyclales	206389|Rhodocyclales	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Complex1_51K,NADH_4Fe-4S
YHH2_k127_3103885_1	580332.Slit_0173	1.861e-271	839.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,44V3W@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Peptidase family U32 C-terminal domain	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
YHH2_k127_3103885_3	580332.Slit_0174	3.651e-162	512.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2VHHI@28216|Betaproteobacteria,44VA9@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
YHH2_k127_3103885_6	580332.Slit_0175	1.579e-59	208.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,44VVZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
YHH2_k127_3103885_0	395494.Galf_2645	1.557e-289	891.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,44UYB@713636|Nitrosomonadales	28216|Betaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
YHH2_k127_3103885_2	580332.Slit_0177	2.519e-248	767.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,44VJJ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YHH2_k127_3103885_5	580332.Slit_0178	1.619e-135	436.0	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,2VKN0@28216|Betaproteobacteria,44VQM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Bacterial lipid A biosynthesis acyltransferase	htrB_2	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
YHH2_k127_3103885_4	580332.Slit_0179	4.441e-154	492.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria,44V9R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Bacterial lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
YHH2_k127_3146224_1	395494.Galf_2323	2.201e-65	230.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,2VR8U@28216|Betaproteobacteria,44W0Y@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH2_k127_3146224_0	395494.Galf_2322	5.922e-91	311.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	regB	-	2.7.13.3	ko:K07717,ko:K15011	ko02020,map02020	M00518,M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_5,HisKA
YHH2_k127_3146224_2	62928.azo1372	5.025e-08	55.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_3162459_5	580332.Slit_1506	6.394e-96	317.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,44VDU@713636|Nitrosomonadales	28216|Betaproteobacteria	E	ACT domain	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
YHH2_k127_3162459_6	580332.Slit_1506	3.197e-92	304.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,44VDU@713636|Nitrosomonadales	28216|Betaproteobacteria	E	ACT domain	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
YHH2_k127_3162459_0	580332.Slit_1505	1.173e-301	933.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,44VNW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH2_k127_3162459_2	580332.Slit_1504	3.943e-176	561.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2VJ4P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
YHH2_k127_3162459_13	1173023.KE650771_gene588	1.386e-17	89.0	COG2442@1|root,COG2442@2|Bacteria,1G9FC@1117|Cyanobacteria,1JMBK@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YHH2_k127_3162459_10	1173028.ANKO01000020_gene5475	6.105e-37	142.0	COG4634@1|root,COG4634@2|Bacteria,1GA03@1117|Cyanobacteria,1HDVT@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3162459_9	398767.Glov_2072	1.58e-40	155.0	COG0515@1|root,COG0515@2|Bacteria,1N79H@1224|Proteobacteria,42XTB@68525|delta/epsilon subdivisions,2WWHE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
YHH2_k127_3162459_7	398767.Glov_2076	3.823e-50	192.0	COG0515@1|root,COG0515@2|Bacteria	398767.Glov_2076|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3162459_1	580332.Slit_1503	9.563e-204	636.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,44VCA@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH2_k127_3162459_3	1123053.AUDG01000013_gene1134	3.742e-126	412.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1S054@1236|Gammaproteobacteria,1X24N@135613|Chromatiales	135613|Chromatiales	L	C-5 cytosine-specific DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	DNA_methylase
YHH2_k127_3162459_8	742727.HMPREF9447_04402	1.211e-45	178.0	COG2206@1|root,COG2206@2|Bacteria,4PHFN@976|Bacteroidetes,2FS0D@200643|Bacteroidia,4AQU3@815|Bacteroidaceae	976|Bacteroidetes	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3162459_4	742727.HMPREF9447_04403	8.733e-126	423.0	COG0210@1|root,COG0210@2|Bacteria,4PEKY@976|Bacteroidetes,2FRQ0@200643|Bacteroidia,4AQAC@815|Bacteroidaceae	976|Bacteroidetes	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3162459_14	1424334.W822_13910	1.516e-12	68.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,3T2CZ@506|Alcaligenaceae	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH2_k127_3172400_1	580332.Slit_1171	2.732e-177	559.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VJI3@28216|Betaproteobacteria,44VGD@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH2_k127_3172400_2	1304883.KI912532_gene1122	1.334e-22	100.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,2VVT0@28216|Betaproteobacteria,2KXPG@206389|Rhodocyclales	206389|Rhodocyclales	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
YHH2_k127_3172400_0	580332.Slit_2054	3.462e-181	569.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,44V6M@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
YHH2_k127_3187437_2	1121116.KB894765_gene675	5.153e-183	582.0	COG0226@1|root,COG0226@2|Bacteria,1PGT2@1224|Proteobacteria,2VI07@28216|Betaproteobacteria,4A9XX@80864|Comamonadaceae	28216|Betaproteobacteria	P	T5orf172	-	-	-	-	-	-	-	-	-	-	-	-	MUG113,T5orf172
YHH2_k127_3187437_1	1504672.669787402	0.0	1228.0	COG1061@1|root,COG1061@2|Bacteria,1PPCG@1224|Proteobacteria,2VMJS@28216|Betaproteobacteria,4ABH5@80864|Comamonadaceae	28216|Betaproteobacteria	KL	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C
YHH2_k127_3187437_3	1121939.L861_15820	8.889e-157	501.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,1RPNB@1236|Gammaproteobacteria,1XIB0@135619|Oceanospirillales	135619|Oceanospirillales	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
YHH2_k127_3187437_0	391735.Veis_1748	0.0	1485.0	COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,2VMKD@28216|Betaproteobacteria,4ACZU@80864|Comamonadaceae	28216|Betaproteobacteria	V	type II restriction enzyme, methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
YHH2_k127_3187437_6	28229.ND2E_0736	2.341e-06	60.0	COG3415@1|root,COG3415@2|Bacteria,1QUVI@1224|Proteobacteria,1S7IJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Tn7-like transposition protein D	-	-	-	-	-	-	-	-	-	-	-	-	TniQ,TnsD
YHH2_k127_3187437_4	1123487.KB892866_gene1710	1.62e-15	76.0	COG2963@1|root,COG2963@2|Bacteria,1RK9V@1224|Proteobacteria,2VQR1@28216|Betaproteobacteria,2KYMF@206389|Rhodocyclales	206389|Rhodocyclales	L	Tn7-like transposition protein D	-	-	-	-	-	-	-	-	-	-	-	-	TniQ,TnsD
YHH2_k127_3189725_1	580332.Slit_0982	1.682e-55	195.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,44VCR@713636|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter transmembrane region	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH2_k127_3189725_5	62928.azo1372	6.579e-08	54.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_3189725_0	580332.Slit_0983	1.722e-114	376.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,44V9A@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
YHH2_k127_3189725_2	1282356.H045_04495	1.316e-47	175.0	COG5611@1|root,COG5611@2|Bacteria,1N9JM@1224|Proteobacteria,1RV6T@1236|Gammaproteobacteria,1YTIE@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_3189725_3	216595.PFLU_1618	1.123e-25	108.0	COG2002@1|root,COG2002@2|Bacteria,1NIC5@1224|Proteobacteria	1224|Proteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PrlF_antitoxin
YHH2_k127_3189725_4	1283300.ATXB01000002_gene2720	7.176e-14	79.0	2BZB1@1|root,32R4P@2|Bacteria,1RH72@1224|Proteobacteria,1SW1S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_320473_3	580332.Slit_1030	3.148e-185	581.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2VHQY@28216|Betaproteobacteria,44V21@713636|Nitrosomonadales	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
YHH2_k127_320473_5	395494.Galf_1983	7.416e-129	415.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2VMUD@28216|Betaproteobacteria,44VN0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH2_k127_320473_0	580332.Slit_1032	0.0	1110.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2VIYX@28216|Betaproteobacteria,44VXW@713636|Nitrosomonadales	28216|Betaproteobacteria	C	nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein	cysI	-	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
YHH2_k127_320473_4	580332.Slit_1033	1.708e-132	425.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2VIR0@28216|Betaproteobacteria,44V6T@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YHH2_k127_320473_2	580332.Slit_1034	1.537e-189	593.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2VJH9@28216|Betaproteobacteria,44V50@713636|Nitrosomonadales	28216|Betaproteobacteria	EH	Phosphoadenosine phosphosulfate reductase family	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YHH2_k127_320473_1	580332.Slit_1035	1.63e-233	727.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2VHYV@28216|Betaproteobacteria,44VMN@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Elongation factor Tu GTP binding domain	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH2_k127_3208567_1	580332.Slit_1748	1.985e-309	957.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,44VBM@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_3208567_17	946483.Cenrod_2192	7.85e-100	338.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VIXP@28216|Betaproteobacteria,4AC75@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YHH2_k127_3208567_31	977880.RALTA_A1639	1.153e-42	160.0	COG0394@1|root,COG0394@2|Bacteria,1N0DZ@1224|Proteobacteria,2VT1B@28216|Betaproteobacteria,1K8BQ@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	epsP	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YHH2_k127_3208567_7	977880.RALTA_A1638	1.016e-209	675.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,2VGZW@28216|Betaproteobacteria,1KFCI@119060|Burkholderiaceae	28216|Betaproteobacteria	D	TIGRFAM exopolysaccharide transport protein family	epsB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,GNVR,Wzz
YHH2_k127_3208567_18	686340.Metal_1930	5.755e-86	292.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1XF6C@135618|Methylococcales	135618|Methylococcales	P	Inositol monophosphatase family	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
YHH2_k127_3208567_10	498761.HM1_1167	1.891e-143	459.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia	186801|Clostridia	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YHH2_k127_3208567_2	765913.ThidrDRAFT_2799	1.077e-264	827.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1WWRV@135613|Chromatiales	135613|Chromatiales	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
YHH2_k127_3208567_24	1415630.U771_09327	1.717e-68	235.0	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,1RXAQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	wxcM	-	-	-	-	-	-	-	-	-	-	-	FdtA,Hexapep
YHH2_k127_3208567_22	640081.Dsui_1768	1.995e-72	246.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	fdtA_2	-	-	-	-	-	-	-	-	-	-	-	FdtA
YHH2_k127_3208567_9	398767.Glov_0790	1.648e-165	527.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,43UJU@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	DegT/DnrJ/EryC1/StrS aminotransferase family	fdtB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH2_k127_3208567_27	1211814.CAPG01000027_gene1255	2.763e-61	228.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	wzxE	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
YHH2_k127_3208567_26	545694.TREPR_0339	1.069e-62	229.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wbsE	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glycos_transf_1
YHH2_k127_3208567_36	658612.MD26_04380	9.097e-07	61.0	2DRIC@1|root,33BXM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3208567_8	371731.Rsw2DRAFT_2506	2.247e-168	537.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,2V835@28211|Alphaproteobacteria,1FC7C@1060|Rhodobacter	28211|Alphaproteobacteria	H	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH2_k127_3208567_15	371731.Rsw2DRAFT_2507	3.943e-109	362.0	COG0451@1|root,COG0451@2|Bacteria,1NRK1@1224|Proteobacteria,2U44C@28211|Alphaproteobacteria,1FCGS@1060|Rhodobacter	28211|Alphaproteobacteria	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH2_k127_3208567_20	251221.35212760	4.334e-76	265.0	COG4424@1|root,COG4424@2|Bacteria,1G9Y1@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
YHH2_k127_3208567_28	489825.LYNGBM3L_57640	1.614e-50	192.0	COG0726@1|root,COG0726@2|Bacteria,1G6FJ@1117|Cyanobacteria,1HB8K@1150|Oscillatoriales	1117|Cyanobacteria	G	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
YHH2_k127_3208567_13	371731.Rsw2DRAFT_2508	7.863e-115	381.0	COG0457@1|root,COG0457@2|Bacteria	371731.Rsw2DRAFT_2508|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3208567_16	330214.NIDE3173	1.075e-106	357.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
YHH2_k127_3208567_12	371731.Rsw2DRAFT_2509	8.896e-130	424.0	COG0438@1|root,COG0438@2|Bacteria,1MUYN@1224|Proteobacteria,2U34Q@28211|Alphaproteobacteria,1FCEK@1060|Rhodobacter	28211|Alphaproteobacteria	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glyco_trans_1_2,Glyco_trans_1_4,Glycos_transf_1
YHH2_k127_3208567_25	323850.Shew_1417	8.014e-63	228.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria,2QAFA@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55)	wecA	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
YHH2_k127_3208567_34	395494.Galf_1294	1.477e-33	138.0	2DNDN@1|root,32X06@2|Bacteria,1N39Y@1224|Proteobacteria,2VUZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	(Lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	YjbF
YHH2_k127_3208567_4	85643.Tmz1t_3793	3.104e-255	818.0	COG0671@1|root,COG3170@1|root,COG0671@2|Bacteria,COG3170@2|Bacteria,1QVRT@1224|Proteobacteria,2VMVN@28216|Betaproteobacteria,2KYK2@206389|Rhodocyclales	206389|Rhodocyclales	NU	Exopolysaccharide biosynthesis protein YbjH	-	-	-	-	-	-	-	-	-	-	-	-	YjbH
YHH2_k127_3208567_23	580332.Slit_1747	3.749e-70	240.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2VR79@28216|Betaproteobacteria,44VTR@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
YHH2_k127_3208567_30	580332.Slit_1746	2.017e-44	163.0	COG2965@1|root,COG2965@2|Bacteria,1PXB0@1224|Proteobacteria,2WCSV@28216|Betaproteobacteria,44WM5@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA replication, synthesis of RNA primer	-	-	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
YHH2_k127_3208567_29	580332.Slit_1745	8.886e-45	163.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2VTWT@28216|Betaproteobacteria,44VYS@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
YHH2_k127_3208567_19	580332.Slit_1744	1.668e-76	258.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2VR40@28216|Betaproteobacteria,44VTS@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L9, N-terminal domain	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
YHH2_k127_3208567_3	580332.Slit_1743	4.587e-262	811.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,44VPB@713636|Nitrosomonadales	28216|Betaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
YHH2_k127_3208567_11	580332.Slit_1623	2.105e-136	437.0	COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,2VQDG@28216|Betaproteobacteria,44VNV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	SpoU rRNA Methylase family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
YHH2_k127_3208567_33	580332.Slit_1622	1.143e-38	145.0	COG0298@1|root,COG0680@1|root,COG0298@2|Bacteria,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,2VJ4W@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Hydrogenase expression formation protein	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
YHH2_k127_3208567_37	1120999.JONM01000021_gene108	1.934e-05	53.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,2KSSW@206351|Neisseriales	206351|Neisseriales	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
YHH2_k127_3208567_21	580332.Slit_1622	2.113e-73	249.0	COG0298@1|root,COG0680@1|root,COG0298@2|Bacteria,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,2VJ4W@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Hydrogenase expression formation protein	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
YHH2_k127_3208567_6	580332.Slit_1621	3.707e-218	679.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VK03@28216|Betaproteobacteria	28216|Betaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
YHH2_k127_3208567_14	580332.Slit_1620	8.917e-112	364.0	COG2181@1|root,COG2181@2|Bacteria,1QQCT@1224|Proteobacteria,2VU6P@28216|Betaproteobacteria	28216|Betaproteobacteria	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3208567_5	580332.Slit_1619	2.939e-250	775.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,2VJGA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
YHH2_k127_3208567_0	580332.Slit_1617	0.0	1131.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
YHH2_k127_3208567_35	864073.HFRIS_022298	1.07e-25	108.0	COG4118@1|root,COG4118@2|Bacteria,1NAEH@1224|Proteobacteria,2VWR1@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_3208567_32	1120999.JONM01000007_gene1869	4.344e-42	159.0	COG3744@1|root,COG3744@2|Bacteria,1RJ4K@1224|Proteobacteria,2VTJR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_3270359_3	325452.fgenesh_scip_prom.46568.10255	2.566e-06	51.0	COG0461@1|root,KOG1377@2759|Eukaryota,3Q8M9@4776|Peronosporales	4776|Peronosporales	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	2.4.2.10,4.1.1.23	ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
YHH2_k127_3270359_0	130081.XP_005704774.1	7.108e-125	408.0	COG0122@1|root,COG0458@1|root,KOG0370@2759|Eukaryota,KOG2875@2759|Eukaryota	2759|Eukaryota	L	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity	URA2	GO:0000050,GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003922,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006142,GO:0006206,GO:0006207,GO:0006220,GO:0006244,GO:0006259,GO:0006281,GO:0006282,GO:0006284,GO:0006285,GO:0006289,GO:0006304,GO:0006355,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0008652,GO:0009056,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009166,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009889,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010605,GO:0016020,GO:0016021,GO:0016053,GO:0016363,GO:0016604,GO:0016607,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019104,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019627,GO:0019637,GO:0019692,GO:0019752,GO:0019856,GO:0031224,GO:0031323,GO:0031324,GO:0031326,GO:0031974,GO:0031981,GO:0032356,GO:0032357,GO:0032991,GO:0033554,GO:0033683,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045007,GO:0045008,GO:0045738,GO:0045934,GO:0045984,GO:0046112,GO:0046386,GO:0046394,GO:0046434,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0051716,GO:0055086,GO:0060255,GO:0062012,GO:0062014,GO:0065007,GO:0070013,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0072529,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901135,GO:1901136,GO:1901291,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2000779,GO:2000780,GO:2001020,GO:2001021,GO:2001141	2.1.3.2,3.5.2.3,4.2.99.18,6.3.5.5	ko:K01954,ko:K01955,ko:K03660,ko:K11540,ko:K11541,ko:K19656	ko00240,ko00250,ko01100,ko03410,map00240,map00250,map01100,map03410	M00051	R00256,R00575,R01395,R01397,R01993,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00632,RC02750,RC02798,RC02850,RC03314	ko00000,ko00001,ko00002,ko01000,ko01002,ko03036,ko03400	-	-	-	CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,HhH-GPD,MGS,OGG_N,OTCace,OTCace_N
YHH2_k127_3270359_1	572477.Alvin_0642	3.68e-124	413.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
YHH2_k127_3270359_2	251229.Chro_2922	7.695e-91	302.0	28IMC@1|root,2Z8MV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3284816_1	580332.Slit_2556	3.107e-154	492.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,2W04K@28216|Betaproteobacteria	28216|Betaproteobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
YHH2_k127_3284816_0	439235.Dalk_1717	8.545e-208	656.0	COG2865@1|root,COG2865@2|Bacteria,1MXG1@1224|Proteobacteria,42M7P@68525|delta/epsilon subdivisions,2WKGM@28221|Deltaproteobacteria,2MITW@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
YHH2_k127_3284816_3	1182590.BN5_02836	1.378e-40	154.0	COG4804@1|root,COG4804@2|Bacteria,1NBWK@1224|Proteobacteria,1RY9R@1236|Gammaproteobacteria,1YGAE@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1016)	yhcG	-	-	-	-	-	-	-	-	-	-	-	DUF1016
YHH2_k127_3284816_2	350688.Clos_1867	5.308e-57	227.0	COG4096@1|root,COG5635@1|root,COG4096@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	2.1.1.72,3.1.21.3,3.1.21.4	ko:K01153,ko:K01155,ko:K03427,ko:K09384	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N,HSDR_N_2,N6_Mtase,ResIII,T5orf172
YHH2_k127_3284816_6	580332.Slit_2555	7.28e-12	66.0	COG0636@1|root,COG0636@2|Bacteria,1REA9@1224|Proteobacteria,2W4JN@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
YHH2_k127_3284816_4	56110.Oscil6304_1589	1.706e-36	142.0	COG5611@1|root,COG5611@2|Bacteria,1GBBH@1117|Cyanobacteria	1117|Cyanobacteria	S	PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3284816_5	580332.Slit_2555	1.506e-24	105.0	COG0636@1|root,COG0636@2|Bacteria,1REA9@1224|Proteobacteria,2W4JN@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
YHH2_k127_3292344_14	1485544.JQKP01000003_gene231	5.317e-16	78.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,44V0J@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH2_k127_3292344_2	580332.Slit_0706	0.0	1070.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,44VC0@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
YHH2_k127_3292344_3	580332.Slit_0707	1.606e-152	485.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,44V3J@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Type I GTP cyclohydrolase folE2	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
YHH2_k127_3292344_7	551789.ATVJ01000001_gene1854	8.544e-62	226.0	COG5397@1|root,COG5397@2|Bacteria,1R4MR@1224|Proteobacteria,2U2XQ@28211|Alphaproteobacteria,43ZES@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_8
YHH2_k127_3292344_4	580332.Slit_0709	8.852e-118	381.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2VJEI@28216|Betaproteobacteria,44V94@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
YHH2_k127_3292344_11	322710.Avin_40600	1.236e-36	140.0	COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,1SCNC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	addiction module killer protein	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
YHH2_k127_3292344_10	1005048.CFU_1499	1.564e-38	146.0	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,2VTZN@28216|Betaproteobacteria,4757W@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH2_k127_3292344_1	580332.Slit_0711	0.0	1333.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2VJF3@28216|Betaproteobacteria,44VKM@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PD-(D/E)XK nuclease superfamily	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
YHH2_k127_3292344_0	580332.Slit_0712	0.0	1564.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VI92@28216|Betaproteobacteria,44V4X@713636|Nitrosomonadales	28216|Betaproteobacteria	L	AAA domain	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH2_k127_3292344_13	757424.Hsero_4089	4.194e-25	115.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	2.3.1.51	ko:K00655,ko:K07451	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048	-	-	-	DUF262,DUF968,HNH
YHH2_k127_3292344_15	909663.KI867150_gene1656	3.939e-13	72.0	2C6B2@1|root,335GA@2|Bacteria,1NG8G@1224|Proteobacteria,42X8T@68525|delta/epsilon subdivisions,2WSSY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3292344_12	631362.Thi970DRAFT_00247	2.793e-29	119.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,1SESI@1236|Gammaproteobacteria,1WZD8@135613|Chromatiales	135613|Chromatiales	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_3292344_16	1175306.GWL_32940	7.545e-09	59.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,472DA@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
YHH2_k127_3292344_9	316067.Geob_1842	2.311e-49	184.0	COG3920@1|root,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YHH2_k127_3292344_6	56107.Cylst_6349	7.178e-72	245.0	COG0454@1|root,COG0456@2|Bacteria,1G5WX@1117|Cyanobacteria,1HQQR@1161|Nostocales	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH2_k127_3292344_8	1280390.CBQR020000102_gene2476	2.957e-55	202.0	COG1028@1|root,COG1028@2|Bacteria,1TS27@1239|Firmicutes,4HDAK@91061|Bacilli,26TE6@186822|Paenibacillaceae	91061|Bacilli	IQ	related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH2_k127_3292344_5	1163617.SCD_n01089	5.314e-81	274.0	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria	1224|Proteobacteria	E	Glycine cleavage system	gcvR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
YHH2_k127_3292600_2	498848.TaqDRAFT_4878	2.563e-46	193.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3292600_3	1121035.AUCH01000002_gene1604	8.648e-30	120.0	2E63D@1|root,330SG@2|Bacteria,1N4HX@1224|Proteobacteria,2VTX6@28216|Betaproteobacteria,2KXCX@206389|Rhodocyclales	206389|Rhodocyclales	S	Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO	cowN	-	-	ko:K21694	-	-	-	-	ko00000	-	-	-	-
YHH2_k127_3292600_1	580332.Slit_0925	2.022e-92	307.0	COG0716@1|root,COG0716@2|Bacteria,1MX7F@1224|Proteobacteria,2VS8P@28216|Betaproteobacteria,44W9P@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Flavodoxin	-	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
YHH2_k127_3292600_0	580332.Slit_0926	1.446e-98	324.0	297UU@1|root,2ZV1D@2|Bacteria,1MXFE@1224|Proteobacteria,2VIEE@28216|Betaproteobacteria,44WA8@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3294452_14	580332.Slit_0818	1.026e-129	420.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,2VWPY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
YHH2_k127_3294452_11	580332.Slit_1352	3.593e-150	484.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2VPHG@28216|Betaproteobacteria,44VWU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfatase-modifying factor enzyme 1	prkC1	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase,SHOCT
YHH2_k127_3294452_10	1485544.JQKP01000001_gene990	1.02e-150	482.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,2VM8T@28216|Betaproteobacteria,44WBK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	ADP-ribosylglycohydrolase	draG	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
YHH2_k127_3294452_18	580332.Slit_0833	6.597e-88	293.0	2BDS5@1|root,327FW@2|Bacteria,1N15E@1224|Proteobacteria,2VUB3@28216|Betaproteobacteria,44WCK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	NifQ	nifQ	-	-	ko:K15790	-	-	-	-	ko00000	-	-	-	NifQ
YHH2_k127_3294452_21	1485544.JQKP01000001_gene992	2.223e-67	231.0	COG0633@1|root,COG0633@2|Bacteria,1N22M@1224|Proteobacteria,2VSHC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
YHH2_k127_3294452_29	1485544.JQKP01000001_gene993	2.639e-33	133.0	COG1018@1|root,COG1018@2|Bacteria,1PXB2@1224|Proteobacteria,2WCSW@28216|Betaproteobacteria,44WM7@713636|Nitrosomonadales	28216|Betaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
YHH2_k127_3294452_22	580332.Slit_0835	6.531e-63	218.0	COG1393@1|root,COG1393@2|Bacteria,1MZ7Z@1224|Proteobacteria,2VT4B@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
YHH2_k127_3294452_25	580332.Slit_0836	4.538e-44	161.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VW4D@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
YHH2_k127_3294452_5	580332.Slit_0837	1.668e-296	915.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,2VJBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cofactor biosynthesis protein NifB	nifB	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
YHH2_k127_3294452_24	580332.Slit_2823	2.653e-46	168.0	COG1872@1|root,COG1872@2|Bacteria,1PW6G@1224|Proteobacteria,2WBRH@28216|Betaproteobacteria,44WKF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
YHH2_k127_3294452_16	580332.Slit_2824	1.204e-108	356.0	COG1187@1|root,COG1187@2|Bacteria,1PYTZ@1224|Proteobacteria,2VNU1@28216|Betaproteobacteria,44VFC@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	S4
YHH2_k127_3294452_31	580332.Slit_2825	4.954e-31	123.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,2VW2Y@28216|Betaproteobacteria,44W1K@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DNA-binding protein VF530	-	-	-	-	-	-	-	-	-	-	-	-	VF530
YHH2_k127_3294452_17	523791.Kkor_2178	4.542e-100	332.0	2ENZN@1|root,32N3M@2|Bacteria,1Q8N6@1224|Proteobacteria,1RU3M@1236|Gammaproteobacteria,1XQJ4@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3294452_1	580332.Slit_2833	0.0	1642.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,44V1E@713636|Nitrosomonadales	28216|Betaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
YHH2_k127_3294452_13	580332.Slit_2834	6.45e-132	422.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,44VF9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Possible lysine decarboxylase	yvdD_2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH2_k127_3294452_27	580332.Slit_2835	1.372e-38	147.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,2VVT5@28216|Betaproteobacteria,44VZF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
YHH2_k127_3294452_9	580332.Slit_2836	3.884e-154	491.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,44V2D@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
YHH2_k127_3294452_19	1123261.AXDW01000007_gene2155	4.705e-81	309.0	COG1018@1|root,COG2373@1|root,COG4932@1|root,COG1018@2|Bacteria,COG2373@2|Bacteria,COG4932@2|Bacteria,1QW47@1224|Proteobacteria,1RQU1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1
YHH2_k127_3294452_0	580332.Slit_0115	0.0	2879.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,44VD7@713636|Nitrosomonadales	28216|Betaproteobacteria	E	glutamate synthase alpha subunit domain protein	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
YHH2_k127_3294452_4	580332.Slit_0116	1.421e-303	935.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2VIHR@28216|Betaproteobacteria,44VJA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
YHH2_k127_3294452_7	580332.Slit_0117	3.939e-225	700.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria,44V4K@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH2_k127_3294452_2	580332.Slit_0118	0.0	1261.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,44UY9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
YHH2_k127_3294452_35	1410619.SRDD_22870	1.906e-15	79.0	2EP72@1|root,33GTT@2|Bacteria,1NJ0W@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3294452_32	324925.Ppha_1759	2.578e-30	122.0	29GJ5@1|root,303GV@2|Bacteria,1FFM0@1090|Chlorobi	1090|Chlorobi	S	addiction module component, TIGR02574 family	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
YHH2_k127_3294452_28	324925.Ppha_1758	2.916e-37	141.0	COG3668@1|root,COG3668@2|Bacteria,1FFJD@1090|Chlorobi	1090|Chlorobi	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3294452_30	765914.ThisiDRAFT_2836	3.698e-32	128.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,1WZ7T@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
YHH2_k127_3294452_34	757424.Hsero_3426	3.204e-21	97.0	2DPYH@1|root,333YR@2|Bacteria,1NF9G@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH2_k127_3294452_6	580332.Slit_0120	7.739e-245	762.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,44VFX@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YHH2_k127_3294452_8	580332.Slit_0121	2.043e-163	516.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
YHH2_k127_3294452_33	118161.KB235922_gene1511	2.164e-22	97.0	COG1724@1|root,COG1724@2|Bacteria,1G91K@1117|Cyanobacteria,3VKRB@52604|Pleurocapsales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_3294452_23	383372.Rcas_2885	2.629e-47	174.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	ycfB	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
YHH2_k127_3294452_3	580332.Slit_0126	0.0	1071.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,44V7S@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YHH2_k127_3294452_26	580332.Slit_0127	3.255e-40	156.0	COG3087@1|root,COG3087@2|Bacteria,1N4QG@1224|Proteobacteria,2VUXF@28216|Betaproteobacteria,44VZ6@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
YHH2_k127_3294452_20	580332.Slit_0128	6.808e-70	243.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,44VUB@713636|Nitrosomonadales	28216|Betaproteobacteria	O	DSBA-like thioredoxin domain	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin_4
YHH2_k127_3294452_15	580332.Slit_0129	2.309e-118	386.0	COG4221@1|root,COG4221@2|Bacteria,1QTVZ@1224|Proteobacteria,2WGPF@28216|Betaproteobacteria,44UYR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH2_k127_3294452_12	572477.Alvin_0458	1.688e-140	471.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1SJP8@1236|Gammaproteobacteria,1X2T7@135613|Chromatiales	135613|Chromatiales	PT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1
YHH2_k127_3299301_1	580332.Slit_0959	4.265e-216	672.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,44VPG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
YHH2_k127_3299301_3	580332.Slit_0958	1.014e-165	526.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,44V4D@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
YHH2_k127_3299301_5	580332.Slit_0955	6.382e-90	299.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,44VT0@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH2_k127_3299301_2	580332.Slit_0954	1.034e-204	640.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,44VAS@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
YHH2_k127_3299301_4	1163617.SCD_n00492	5.06e-108	361.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2VJCC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	ynaI	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
YHH2_k127_3299301_0	1297569.MESS2_30043	0.0	1249.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG0553 Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH2_k127_3299384_1	580332.Slit_1023	5.232e-66	226.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,44VFG@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YHH2_k127_3299384_0	580332.Slit_1024	2.09e-227	713.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,44VA2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH2_k127_3299384_2	1485544.JQKP01000018_gene594	2.203e-35	136.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,44W0I@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
YHH2_k127_330840_12	933262.AXAM01000181_gene2999	1.31e-12	71.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2WK0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_330840_13	1415778.JQMM01000001_gene2084	2.177e-12	70.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_330840_6	580332.Slit_1493	8.485e-91	302.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2VQI2@28216|Betaproteobacteria,44VU9@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YHH2_k127_330840_0	580332.Slit_1492	0.0	1102.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria,44VII@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
YHH2_k127_330840_3	580332.Slit_1491	2.368e-121	391.0	COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,2VQ3T@28216|Betaproteobacteria	28216|Betaproteobacteria	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH2_k127_330840_2	903818.KI912268_gene1722	2.036e-158	506.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
YHH2_k127_330840_11	580332.Slit_2547	5.073e-30	124.0	COG2944@1|root,COG2944@2|Bacteria,1N1C3@1224|Proteobacteria,2WHMH@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	ko:K13655	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	MqsA_antitoxin
YHH2_k127_330840_4	580332.Slit_1477	1.898e-99	327.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2VI7G@28216|Betaproteobacteria,44VQ2@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
YHH2_k127_330840_5	580332.Slit_1476	5.549e-95	315.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2VQBC@28216|Betaproteobacteria,44VVE@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM class II aldolase adducin family protein	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
YHH2_k127_330840_1	580332.Slit_1539	1.011e-290	895.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,44V1T@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH2_k127_330840_14	1502770.JQMG01000001_gene2057	3.652e-08	55.0	2DT3B@1|root,33IHT@2|Bacteria,1NK4F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_330840_16	1408444.JHYC01000008_gene1427	4.933e-06	49.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_330840_7	292415.Tbd_0943	5.291e-85	296.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VHG5@28216|Betaproteobacteria,1KRH2@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Arm DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
YHH2_k127_330840_9	1177179.A11A3_13895	5.235e-63	227.0	COG3464@1|root,COG3464@2|Bacteria,1R97S@1224|Proteobacteria,1RRBR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	TrfA protein	-	-	-	-	-	-	-	-	-	-	-	-	TrfA
YHH2_k127_330840_8	395494.Galf_0870	7.035e-75	261.0	COG5534@1|root,COG5534@2|Bacteria,1MXQ0@1224|Proteobacteria,2VJHV@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Replication initiator protein A	-	-	-	-	-	-	-	-	-	-	-	-	RPA
YHH2_k127_332308_8	316067.Geob_2051	8.2e-171	554.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,42TQ5@68525|delta/epsilon subdivisions,2WQ0T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH2_k127_332308_15	196490.AUEZ01000145_gene1659	1.802e-36	141.0	COG2944@1|root,COG2944@2|Bacteria,1N05Y@1224|Proteobacteria,2UCCG@28211|Alphaproteobacteria,3K1DT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Helix-turn-helix	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
YHH2_k127_332308_13	1121004.ATVC01000109_gene1940	1.152e-57	201.0	COG2944@1|root,COG2944@2|Bacteria,1N05Y@1224|Proteobacteria,2VSDE@28216|Betaproteobacteria,2KRXA@206351|Neisseriales	206351|Neisseriales	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH2_k127_332308_14	243265.plu2130	2.615e-43	161.0	COG4737@1|root,COG4737@2|Bacteria,1NAIM@1224|Proteobacteria,1SAPB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	RelE toxin of RelE / RelB toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
YHH2_k127_332308_10	580332.Slit_1401	5.229e-118	383.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,44VIT@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
YHH2_k127_332308_4	580332.Slit_1402	1.599e-221	694.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,44V56@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
YHH2_k127_332308_7	243233.MCA1083	3.998e-174	573.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphatase	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
YHH2_k127_332308_1	580332.Slit_1367	1.995e-230	719.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,44VD3@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
YHH2_k127_332308_0	580332.Slit_1368	1.497e-263	821.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,44V80@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
YHH2_k127_332308_11	580332.Slit_1369	1.199e-68	234.0	COG2076@1|root,COG2076@2|Bacteria,1NAUF@1224|Proteobacteria,2WE9Q@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
YHH2_k127_332308_3	580332.Slit_1370	1.102e-224	698.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,44VGP@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH2_k127_332308_17	491916.RHECIAT_CH0000408	2.647e-17	87.0	2ADU5@1|root,313JU@2|Bacteria,1PSKG@1224|Proteobacteria,2V4QR@28211|Alphaproteobacteria,4BFM1@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Imm50
YHH2_k127_332308_16	1454004.AW11_02701	4.035e-28	114.0	COG4118@1|root,COG4118@2|Bacteria,1NH4W@1224|Proteobacteria	1224|Proteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_332308_12	76114.ebA5197	3.889e-59	210.0	COG0840@1|root,COG0840@2|Bacteria,1QVIE@1224|Proteobacteria,2WGSN@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
YHH2_k127_332308_5	580332.Slit_1372	4.849e-184	577.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,44VI3@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyl transferase family 2	arnC	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
YHH2_k127_332308_9	580332.Slit_1373	1.903e-165	525.0	COG0223@1|root,COG0223@2|Bacteria,1MWH1@1224|Proteobacteria,2VKAI@28216|Betaproteobacteria,44VNB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Formyl transferase, C-terminal domain	pmrIa	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YHH2_k127_332308_2	580332.Slit_1374	2.541e-228	707.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2VJV2@28216|Betaproteobacteria,44UZQ@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	pmrIb	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YHH2_k127_332308_6	580332.Slit_1375	1.056e-174	550.0	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,2VKEP@28216|Betaproteobacteria,44VD4@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Polysaccharide deacetylase	arnD	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
YHH2_k127_332308_18	908937.Prede_0695	2.816e-10	67.0	COG3533@1|root,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes,2FN3P@200643|Bacteroidia	976|Bacteroidetes	V	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	DUF4986,Glyco_hydro_127
YHH2_k127_3468654_5	1121448.DGI_4058	6.797e-87	295.0	COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,42PXV@68525|delta/epsilon subdivisions,2WNAK@28221|Deltaproteobacteria,2MAWU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Capsule polysaccharide biosynthesis protein	-	-	-	ko:K07266	-	-	-	-	ko00000	-	-	-	Capsule_synth
YHH2_k127_3468654_4	857087.Metme_3909	3.312e-100	329.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1XF0R@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
YHH2_k127_3468654_13	981336.F944_00227	6.441e-21	97.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,1SATT@1236|Gammaproteobacteria,3NN8V@468|Moraxellaceae	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH2_k127_3468654_16	1112274.KI911560_gene678	1.049e-11	68.0	COG4456@1|root,COG4456@2|Bacteria,1N7FM@1224|Proteobacteria,2VWHT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_3468654_2	765913.ThidrDRAFT_3676	1.015e-123	406.0	COG0438@1|root,COG0438@2|Bacteria,1R662@1224|Proteobacteria,1RREQ@1236|Gammaproteobacteria,1WWTB@135613|Chromatiales	135613|Chromatiales	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3468654_8	1123368.AUIS01000003_gene1672	1.492e-53	195.0	29XXA@1|root,30JPU@2|Bacteria,1PRTA@1224|Proteobacteria,1T99W@1236|Gammaproteobacteria,2NE2M@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3468654_11	1123354.AUDR01000015_gene303	3.502e-34	133.0	COG1708@1|root,COG1708@2|Bacteria,1QZYB@1224|Proteobacteria,2VW1D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH2_k127_3468654_10	697282.Mettu_2247	1.38e-42	158.0	COG5304@1|root,COG5304@2|Bacteria,1N269@1224|Proteobacteria,1SAZ0@1236|Gammaproteobacteria,1XGGH@135618|Methylococcales	135618|Methylococcales	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
YHH2_k127_3468654_14	1162668.LFE_1276	1.209e-13	74.0	COG2929@1|root,COG2929@2|Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_3468654_1	1232683.ADIMK_1468	2.42e-167	530.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,1RMPQ@1236|Gammaproteobacteria,465RY@72275|Alteromonadaceae	1236|Gammaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
YHH2_k127_3468654_0	583345.Mmol_1025	3.894e-221	689.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2VIBX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
YHH2_k127_3468654_12	29581.BW37_05518	2.659e-33	130.0	COG3093@1|root,COG3093@2|Bacteria,1NA48@1224|Proteobacteria,2VUT2@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
YHH2_k127_3468654_15	1123269.NX02_00200	1.583e-12	77.0	COG4424@1|root,COG4424@2|Bacteria,1QT2Y@1224|Proteobacteria,2UWG8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3468654_7	1278309.KB907100_gene1794	5.231e-56	205.0	2BKZZ@1|root,32FGS@2|Bacteria,1N692@1224|Proteobacteria,1SE1T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
YHH2_k127_3468654_3	153721.MYP_2282	4.881e-117	391.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47M69@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH2_k127_3468654_9	1443111.JASG01000004_gene1682	2.286e-48	183.0	2DN61@1|root,32VRI@2|Bacteria	2|Bacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
YHH2_k127_3468654_6	622637.KE124774_gene2104	6.474e-74	256.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,2TSYD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0110 Acetyltransferase (isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YHH2_k127_3468654_17	338966.Ppro_2445	5.872e-10	72.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,CHU_C,Copper-bind,DUF1080,DUF11
YHH2_k127_3470900_5	1408444.JHYC01000013_gene2473	1.055e-10	65.0	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3470900_3	580332.Slit_1549	5.847e-46	170.0	COG5499@1|root,COG5499@2|Bacteria,1N89F@1224|Proteobacteria,2VWB3@28216|Betaproteobacteria,44WNE@713636|Nitrosomonadales	28216|Betaproteobacteria	K	SMART helix-turn-helix domain protein	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
YHH2_k127_3470900_1	388051.AUFE01000072_gene3853	5.967e-55	194.0	COG4190@1|root,COG4190@2|Bacteria,1RDM2@1224|Proteobacteria,2VTP3@28216|Betaproteobacteria,1K894@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_IclR,MarR
YHH2_k127_3470900_2	977880.pRALTA_0112	5.353e-47	171.0	COG5652@1|root,COG5652@2|Bacteria,1RDK4@1224|Proteobacteria,2VSI8@28216|Betaproteobacteria,1KB4F@119060|Burkholderiaceae	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3470900_0	1158292.JPOE01000005_gene388	0.0	1289.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1QU9I@1224|Proteobacteria,2VHI0@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Type III restriction	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
YHH2_k127_3470900_4	290315.Clim_0655	9.052e-43	157.0	COG3093@1|root,COG3093@2|Bacteria,1FFJY@1090|Chlorobi	1090|Chlorobi	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
YHH2_k127_3484989_3	580332.Slit_2670	5.089e-152	488.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,44WGV@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Molybdenum Cofactor Synthesis C	-	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
YHH2_k127_3484989_8	90814.KL370891_gene72	9.863e-44	173.0	COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,1S473@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
YHH2_k127_3484989_5	395494.Galf_1879	4.834e-85	294.0	COG3850@1|root,COG5001@1|root,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,SBP_bac_3,dCache_1
YHH2_k127_3484989_11	396588.Tgr7_2947	1.139e-09	66.0	2DS56@1|root,33EJS@2|Bacteria,1NQ3F@1224|Proteobacteria,1SI4P@1236|Gammaproteobacteria,1WZU9@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3484989_4	580332.Slit_0996	3.244e-90	300.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2VI3V@28216|Betaproteobacteria,44VDD@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART Protein-tyrosine phosphatase, low molecular weight	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YHH2_k127_3484989_7	395494.Galf_2396	3.041e-50	181.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,2VSJE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Arsenical resistance operon trans-acting repressor ArsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
YHH2_k127_3484989_0	265072.Mfla_1491	8.905e-311	961.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,2VK65@28216|Betaproteobacteria,2KNHW@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
YHH2_k127_3484989_1	395494.Galf_2394	1.511e-192	604.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2VHWA@28216|Betaproteobacteria,44VD8@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Sodium Bile acid symporter family	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
YHH2_k127_3484989_6	580332.Slit_0998	9.222e-68	235.0	COG1595@1|root,COG1595@2|Bacteria,1RHI0@1224|Proteobacteria,2VRKX@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_3484989_2	580332.Slit_0999	1.595e-182	574.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,2VJC7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
YHH2_k127_3484989_9	580332.Slit_1002	4.084e-35	134.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VWXC@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
YHH2_k127_3484989_10	1163617.SCD_n02143	1.178e-17	86.0	COG1230@1|root,COG1230@2|Bacteria,1QUZ5@1224|Proteobacteria,2WGMK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	cation diffusion facilitator family transporter	zitB	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Abhydrolase_6,Cation_efflux
YHH2_k127_3533217_0	580332.Slit_0953	4.446e-264	817.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,44VN3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
YHH2_k127_3533217_1	870187.Thini_4270	1.768e-38	148.0	COG1848@1|root,COG1848@2|Bacteria,1N37Y@1224|Proteobacteria,1SQWG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3533217_2	335541.Swol_2490	1.423e-14	75.0	2AP0U@1|root,31E1Z@2|Bacteria,1W3AK@1239|Firmicutes,257HW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3553299_0	383372.Rcas_4420	1.654e-164	535.0	COG3039@1|root,COG3039@2|Bacteria,2G8AJ@200795|Chloroflexi,377UG@32061|Chloroflexia	32061|Chloroflexia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
YHH2_k127_3553299_1	1089548.KI783301_gene1055	4.765e-16	78.0	COG4974@1|root,COG4974@2|Bacteria,1U0MD@1239|Firmicutes,4HF94@91061|Bacilli	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
YHH2_k127_3559478_9	580332.Slit_2188	1.038e-10	65.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria	1224|Proteobacteria	Q	Methyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
YHH2_k127_3559478_10	76114.ebB120	1.544e-07	53.0	COG5606@1|root,COG5606@2|Bacteria,1NBW2@1224|Proteobacteria,2VRC7@28216|Betaproteobacteria,2KXIK@206389|Rhodocyclales	206389|Rhodocyclales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
YHH2_k127_3559478_5	1485544.JQKP01000007_gene2000	1.103e-41	157.0	COG5304@1|root,COG5304@2|Bacteria,1N269@1224|Proteobacteria,2VV9F@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
YHH2_k127_3559478_8	1162668.LFE_1276	5.799e-15	78.0	COG2929@1|root,COG2929@2|Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_3559478_0	1163617.SCD_n01679	5.54e-308	952.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
YHH2_k127_3559478_4	380394.Lferr_1136	1.236e-49	183.0	COG0454@1|root,COG0454@2|Bacteria,1RHV9@1224|Proteobacteria,1S76Y@1236|Gammaproteobacteria,2ND4H@225057|Acidithiobacillales	225057|Acidithiobacillales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
YHH2_k127_3559478_6	519989.ECTPHS_07961	1.363e-33	130.0	COG4453@1|root,COG4453@2|Bacteria,1N7K8@1224|Proteobacteria,1T0WI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
YHH2_k127_3559478_2	580332.Slit_1789	1.797e-167	563.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	sprD	-	-	-	-	-	-	-	-	-	-	-	DivIVA,PorP_SprF
YHH2_k127_3559478_1	580332.Slit_1787	5.508e-232	728.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,44VPA@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_3559478_3	709032.Sulku_2137	6.489e-84	303.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42YQC@68525|delta/epsilon subdivisions,2YRKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH2_k127_3563134_25	314345.SPV1_12832	3.675e-09	60.0	COG0834@1|root,COG0834@2|Bacteria,1N3ZN@1224|Proteobacteria	1224|Proteobacteria	ET	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
YHH2_k127_3563134_18	292415.Tbd_2422	4.693e-66	227.0	COG3744@1|root,COG3744@2|Bacteria,1N2T0@1224|Proteobacteria,2VTSR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_3563134_21	292415.Tbd_2423	2.433e-38	144.0	COG4118@1|root,COG4118@2|Bacteria,1N7BG@1224|Proteobacteria,2VVQD@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_3563134_7	580332.Slit_1219	3.57e-186	586.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VNB4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA1	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
YHH2_k127_3563134_23	717772.THIAE_02000	2.45e-19	91.0	2EIHU@1|root,33C96@2|Bacteria,1NJTC@1224|Proteobacteria,1SJ8N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH2_k127_3563134_20	118168.MC7420_7831	2.313e-39	154.0	2BUN3@1|root,32PYT@2|Bacteria,1GEJ9@1117|Cyanobacteria,1HG6T@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3563134_15	1175306.GWL_00970	3.269e-130	431.0	COG4637@1|root,COG4637@2|Bacteria,1PFRF@1224|Proteobacteria,2VWDZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
YHH2_k127_3563134_6	395494.Galf_2613	1.663e-188	589.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,44VKR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
YHH2_k127_3563134_13	580332.Slit_1204	1.954e-148	473.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,44VKR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
YHH2_k127_3563134_5	1163617.SCD_n00761	4.422e-205	642.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VK03@28216|Betaproteobacteria	28216|Betaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
YHH2_k127_3563134_10	1163617.SCD_n00762	5.808e-170	537.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VHPC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	formate dehydrogenase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,TAT_signal
YHH2_k127_3563134_8	1163617.SCD_n00763	6.608e-185	585.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,2VNZ5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
YHH2_k127_3563134_2	1163617.SCD_n00764	1.072e-320	986.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hybC	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
YHH2_k127_3563134_19	1163617.SCD_n00765	6.665e-65	225.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,2VJ4W@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Hydrogenase expression formation protein	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
YHH2_k127_3563134_22	1163617.SCD_n00766	3.987e-22	100.0	COG0298@1|root,COG0298@2|Bacteria,1Q1AC@1224|Proteobacteria,2W6DH@28216|Betaproteobacteria	28216|Betaproteobacteria	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
YHH2_k127_3563134_12	395494.Galf_1758	1.479e-158	507.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2VHRC@28216|Betaproteobacteria,44WE8@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Acetokinase family	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase,PTAC,cNMP_binding
YHH2_k127_3563134_0	395494.Galf_1757	0.0	1526.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria,44W5X@713636|Nitrosomonadales	28216|Betaproteobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
YHH2_k127_3563134_9	580332.Slit_1203	2.779e-173	550.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,44WAM@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
YHH2_k127_3563134_17	1182590.BN5_03437	9.712e-68	234.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,1S3ZJ@1236|Gammaproteobacteria,1YJUT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_3563134_14	243233.MCA2787	1.891e-144	467.0	COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,1T3G3@1236|Gammaproteobacteria,1XDZF@135618|Methylococcales	135618|Methylococcales	O	PFAM glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
YHH2_k127_3563134_16	580332.Slit_1191	1.557e-119	387.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,2VI58@28216|Betaproteobacteria,44WEA@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM GntR domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
YHH2_k127_3563134_11	580332.Slit_1190	1.215e-163	517.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VI8S@28216|Betaproteobacteria,44W7N@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30,5.4.2.9	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	-	R00409,R00661	RC00286,RC00287,RC02792	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
YHH2_k127_3563134_4	580332.Slit_1189	6.162e-218	685.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VHJZ@28216|Betaproteobacteria,44W5U@713636|Nitrosomonadales	28216|Betaproteobacteria	H	TIGRFAM 2-methylcitrate synthase citrate synthase II	prpC	-	2.3.3.5	ko:K01659	ko00640,map00640	-	R00931	RC00004,RC00406,RC02827	ko00000,ko00001,ko01000	-	-	-	Citrate_synt
YHH2_k127_3563134_3	580332.Slit_1188	1.215e-299	921.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
YHH2_k127_3563134_1	580332.Slit_1187	0.0	1169.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VI3T@28216|Betaproteobacteria,44W74@713636|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YHH2_k127_3650878_4	1458427.BAWN01000062_gene2195	4.056e-33	131.0	COG1396@1|root,COG1396@2|Bacteria,1NC77@1224|Proteobacteria,2VWSD@28216|Betaproteobacteria,4AJKW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
YHH2_k127_3650878_2	946483.Cenrod_0515	1.027e-49	180.0	COG4683@1|root,COG4683@2|Bacteria,1MZIY@1224|Proteobacteria,2VWKG@28216|Betaproteobacteria,4AIHW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
YHH2_k127_3650878_1	305900.GV64_05375	2.188e-63	229.0	2EZ1I@1|root,33S82@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HipA_C
YHH2_k127_3650878_3	305900.GV64_05370	4.858e-49	183.0	2DM8E@1|root,325ZF@2|Bacteria,1QR34@1224|Proteobacteria,1SMG4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HIRAN domain	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
YHH2_k127_3650878_6	640510.BC1001_4675	4.609e-21	104.0	2ECUD@1|root,336RX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3650878_0	580332.Slit_2782	0.0	1348.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2VH7P@28216|Betaproteobacteria,44V8A@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH2_k127_3650878_5	1236959.BAMT01000005_gene146	1.716e-25	109.0	COG1476@1|root,COG1476@2|Bacteria,1NGZR@1224|Proteobacteria	1224|Proteobacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH2_k127_3651371_0	580332.Slit_0667	1.021e-270	837.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44VP3@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DEAD DEAH box helicase domain protein	dbpA	GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
YHH2_k127_3651371_6	909663.KI867150_gene337	4.635e-58	226.0	COG0823@1|root,COG0823@2|Bacteria,1Q2D4@1224|Proteobacteria,437ZF@68525|delta/epsilon subdivisions,2X39G@28221|Deltaproteobacteria,2MSI3@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3651371_2	580332.Slit_2662	3.606e-96	316.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria,44W6V@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Probable molybdopterin binding domain	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
YHH2_k127_3651371_1	580332.Slit_2663	4.497e-216	676.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,44W86@713636|Nitrosomonadales	28216|Betaproteobacteria	H	MoeA C-terminal region (domain IV)	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
YHH2_k127_3651371_4	580332.Slit_2664	6.274e-86	288.0	COG0746@1|root,COG0746@2|Bacteria,1PJ8F@1224|Proteobacteria,2VYU6@28216|Betaproteobacteria,44WA2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	MobA-like NTP transferase domain	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
YHH2_k127_3651371_3	580332.Slit_2665	1.182e-86	291.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria,44WF6@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Molybdopterin guanine dinucleotide synthesis protein B	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
YHH2_k127_3651371_7	529709.PYCH_16370	1.404e-33	134.0	COG0314@1|root,arCOG00534@2157|Archaea,2XZG1@28890|Euryarchaeota,245HT@183968|Thermococci	183968|Thermococci	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
YHH2_k127_3651762_3	1538295.JY96_05450	1.427e-90	308.0	COG2984@1|root,COG2984@2|Bacteria,1REID@1224|Proteobacteria,2VZBZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
YHH2_k127_3651762_1	1538295.JY96_05440	6.26e-245	775.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2WGU7@28216|Betaproteobacteria,1KPG2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH2_k127_3651762_2	580332.Slit_1327	1.776e-117	415.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,2WHFM@28216|Betaproteobacteria,44WPK@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
YHH2_k127_3651762_4	589865.DaAHT2_0645	4.668e-51	208.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,43CSX@68525|delta/epsilon subdivisions,2X80G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c
YHH2_k127_3651762_0	580332.Slit_1326	2.7e-310	954.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2VHGJ@28216|Betaproteobacteria,44V1K@713636|Nitrosomonadales	28216|Betaproteobacteria	S	fad dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,Pyr_redox_2
YHH2_k127_3651976_1	580332.Slit_2134	2.408e-124	404.0	2DKZI@1|root,310D6@2|Bacteria,1QV1U@1224|Proteobacteria,2VQ0G@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GIDE
YHH2_k127_3651976_4	580332.Slit_2133	4.833e-72	252.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria,2VR7K@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3651976_2	580332.Slit_2132	4.205e-97	323.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,2VQ2A@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LemA Family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
YHH2_k127_3651976_3	1217720.ALOX01000027_gene3732	1.515e-93	315.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2TRJT@28211|Alphaproteobacteria,2JS2M@204441|Rhodospirillales	204441|Rhodospirillales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	LigB
YHH2_k127_3651976_0	580332.Slit_0847	6.363e-152	482.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YHH2_k127_3685813_1	1485544.JQKP01000002_gene1628	2.731e-165	528.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,44V6N@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH2_k127_3685813_0	580332.Slit_2720	1.891e-201	638.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,44UZV@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
YHH2_k127_3685813_2	580332.Slit_2719	1.502e-89	300.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,44V43@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
YHH2_k127_3712316_1	1485544.JQKP01000002_gene1358	5.143e-46	167.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,44V3U@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH2_k127_3712316_0	395494.Galf_2813	4.46e-260	818.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,1MV2W@1224|Proteobacteria,2VHJ2@28216|Betaproteobacteria,44WD6@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
YHH2_k127_3712316_2	96561.Dole_2100	2.629e-31	132.0	COG2518@1|root,COG2518@2|Bacteria,1N1UG@1224|Proteobacteria,430M1@68525|delta/epsilon subdivisions,2WVSY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3712316_4	1280673.AUJJ01000009_gene3044	0.0001408	52.0	2CKIF@1|root,32SCE@2|Bacteria,1VRB9@1239|Firmicutes,24CQQ@186801|Clostridia,4BWDC@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
YHH2_k127_3712316_3	644968.DFW101_2954	2.747e-10	61.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,42M93@68525|delta/epsilon subdivisions,2WK5I@28221|Deltaproteobacteria,2M9GS@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Transposase, IS204 IS1001 IS1096 IS1165	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
YHH2_k127_3759804_1	909663.KI867151_gene3000	5.263e-72	246.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions,2WJUG@28221|Deltaproteobacteria,2MQYT@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
YHH2_k127_3759804_0	580332.Slit_2532	5.085e-200	629.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VHHU@28216|Betaproteobacteria,44V28@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
YHH2_k127_3847242_3	580332.Slit_0739	4.978e-203	636.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,44V3P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
YHH2_k127_3847242_6	580332.Slit_0741	2.842e-110	359.0	COG0748@1|root,COG0748@2|Bacteria,1RFVC@1224|Proteobacteria,2VS07@28216|Betaproteobacteria,44VUT@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx,Pyrid_oxidase_2
YHH2_k127_3847242_5	580332.Slit_0742	2.007e-183	583.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria,44VKC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Virulence factor BrkB	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
YHH2_k127_3847242_12	395494.Galf_2310	2.789e-86	289.0	COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,2VRH2@28216|Betaproteobacteria,44VS8@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
YHH2_k127_3847242_13	580332.Slit_0744	3.712e-65	226.0	COG0526@1|root,COG0526@2|Bacteria,1N4HY@1224|Proteobacteria,2VSKM@28216|Betaproteobacteria,44VXP@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH2_k127_3847242_7	580332.Slit_0745	3.687e-101	334.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,2VHI4@28216|Betaproteobacteria,44VRN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
YHH2_k127_3847242_0	580332.Slit_0746	0.0	1032.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,44VAV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
YHH2_k127_3847242_8	580332.Slit_0747	2.576e-97	324.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria,44VS0@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
YHH2_k127_3847242_11	395494.Galf_2305	1.945e-86	289.0	COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,2VTQI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YHH2_k127_3847242_10	580332.Slit_0749	4.779e-88	301.0	2DG57@1|root,2ZUJK@2|Bacteria,1QZYA@1224|Proteobacteria,2WHPQ@28216|Betaproteobacteria,44VQW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM PEGA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
YHH2_k127_3847242_9	580332.Slit_0750	7.649e-91	300.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria,44VPJ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
YHH2_k127_3847242_4	580332.Slit_0751	3.49e-199	628.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,44V6U@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
YHH2_k127_3847242_1	580332.Slit_2417	6.969e-214	674.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,44VK3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase family M48	yggG_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
YHH2_k127_3847242_2	580332.Slit_2416	2.632e-208	655.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
YHH2_k127_3847242_14	580332.Slit_2414	4.247e-34	134.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,44WKX@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
YHH2_k127_3847242_15	1146883.BLASA_2883	6.103e-09	63.0	COG4828@1|root,COG4828@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
YHH2_k127_386070_0	580332.Slit_1454	4.513e-164	524.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2VHQX@28216|Betaproteobacteria,44W5R@713636|Nitrosomonadales	28216|Betaproteobacteria	S	AFG1-like ATPase	yhcM	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
YHH2_k127_386070_1	296591.Bpro_3822	2.217e-135	436.0	COG4733@1|root,COG4733@2|Bacteria,1QYJ4@1224|Proteobacteria,2WHFV@28216|Betaproteobacteria,4AJWW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
YHH2_k127_386070_2	305700.B447_00175	0.0009916	48.0	COG1572@1|root,COG1864@1|root,COG2931@1|root,COG3209@1|root,COG3386@1|root,COG3391@1|root,COG4254@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,COG4254@2|Bacteria,1MU7T@1224|Proteobacteria,2WHG7@28216|Betaproteobacteria	28216|Betaproteobacteria	MQ	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,TIG
YHH2_k127_3895080_23	580332.Slit_2191	2.548e-83	278.0	2CZS8@1|root,32T71@2|Bacteria,1N4G2@1224|Proteobacteria,2VUSW@28216|Betaproteobacteria,44WJV@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3895080_9	1123377.AUIV01000012_gene721	8.005e-151	486.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria,1XAEU@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH2_k127_3895080_14	395494.Galf_1888	1.268e-128	417.0	28Q4X@1|root,2ZCN0@2|Bacteria,1RA2A@1224|Proteobacteria,2VX5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3895080_4	1123393.KB891328_gene533	8.923e-178	567.0	COG0475@1|root,COG0475@2|Bacteria,1PK6S@1224|Proteobacteria,2VZ60@28216|Betaproteobacteria,1KTFQ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YHH2_k127_3895080_0	580332.Slit_0398	0.0	1166.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,44V8Q@713636|Nitrosomonadales	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
YHH2_k127_3895080_30	580332.Slit_0399	4.504e-32	125.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,44W31@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
YHH2_k127_3895080_19	395494.Galf_0389	2.442e-94	312.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,44VSD@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
YHH2_k127_3895080_13	580332.Slit_0401	9.388e-130	420.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,44VKK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
YHH2_k127_3895080_17	580332.Slit_0402	1.326e-118	388.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,44WCA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART protein phosphatase 2C domain protein	pphA	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
YHH2_k127_3895080_12	580332.Slit_0403	6.168e-130	417.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,44V1Y@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
YHH2_k127_3895080_24	580332.Slit_0665	5.847e-75	256.0	COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,2VR4I@28216|Betaproteobacteria,44VT2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	WLM domain	ygjP	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
YHH2_k127_3895080_3	1288494.EBAPG3_27680	1.041e-182	582.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VJQT@28216|Betaproteobacteria,372AX@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	sad	-	1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79	ko:K00135,ko:K08324	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH2_k127_3895080_5	580332.Slit_2734	2.503e-163	516.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,44V19@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH2_k127_3895080_32	1336208.JADY01000024_gene3822	4.905e-23	107.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VEUJ@28211|Alphaproteobacteria,2JSQT@204441|Rhodospirillales	204441|Rhodospirillales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
YHH2_k127_3895080_25	580332.Slit_2736	3.639e-65	225.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,44VSX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
YHH2_k127_3895080_8	580332.Slit_2737	2.795e-152	486.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,44V1B@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
YHH2_k127_3895080_22	580332.Slit_2738	1.927e-88	294.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,44VVG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
YHH2_k127_3895080_29	580332.Slit_2739	7.307e-45	164.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,44W0A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
YHH2_k127_3895080_20	1385517.N800_11095	3.55e-94	329.0	COG0633@1|root,COG1018@1|root,COG2346@1|root,COG0633@2|Bacteria,COG1018@2|Bacteria,COG2346@2|Bacteria,1REP4@1224|Proteobacteria,1T2XC@1236|Gammaproteobacteria,1XDHE@135614|Xanthomonadales	135614|Xanthomonadales	C	Bacterial-like globin	-	-	-	-	-	-	-	-	-	-	-	-	Bac_globin,FAD_binding_6,Fer2,NAD_binding_1
YHH2_k127_3895080_31	365044.Pnap_0367	2.692e-29	121.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
YHH2_k127_3895080_27	365044.Pnap_0368	4.861e-56	198.0	COG3829@1|root,COG3829@2|Bacteria,1REUB@1224|Proteobacteria,2VRFH@28216|Betaproteobacteria,4AE2K@80864|Comamonadaceae	28216|Betaproteobacteria	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3895080_26	365044.Pnap_0368	4.069e-56	199.0	COG3829@1|root,COG3829@2|Bacteria,1REUB@1224|Proteobacteria,2VRFH@28216|Betaproteobacteria,4AE2K@80864|Comamonadaceae	28216|Betaproteobacteria	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3895080_21	1123504.JQKD01000117_gene390	3.722e-93	322.0	COG1120@1|root,COG2453@1|root,COG1120@2|Bacteria,COG2453@2|Bacteria,1P0GN@1224|Proteobacteria,2VNDH@28216|Betaproteobacteria,4AC63@80864|Comamonadaceae	28216|Betaproteobacteria	HPT	PFAM Dual specificity protein phosphatase	-	-	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	ABC_tran,DSPc
YHH2_k127_3895080_28	637389.Acaty_c2228	1.13e-55	199.0	COG2229@1|root,COG2229@2|Bacteria,1PYIA@1224|Proteobacteria,1S271@1236|Gammaproteobacteria,2NC84@225057|Acidithiobacillales	225057|Acidithiobacillales	S	small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
YHH2_k127_3895080_34	641149.HMPREF9016_01564	3.341e-16	87.0	2DBSQ@1|root,2ZATE@2|Bacteria,1R57P@1224|Proteobacteria,2VNG8@28216|Betaproteobacteria,2KPWQ@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3895080_10	580332.Slit_2740	8.017e-138	443.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,44V5D@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cytochrome C assembly protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
YHH2_k127_3895080_1	580332.Slit_2741	5.21e-262	811.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,44VCY@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
YHH2_k127_3895080_35	580332.Slit_2742	8.15e-08	54.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria,44VFS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH2_k127_3895080_33	1348338.ADILRU_0469	1.501e-19	89.0	COG0286@1|root,COG0286@2|Bacteria,2GKAQ@201174|Actinobacteria,4FKWC@85023|Microbacteriaceae	201174|Actinobacteria	V	N-6 DNA Methylase	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
YHH2_k127_3895080_6	767029.HMPREF9154_2901	5.409e-161	512.0	COG3943@1|root,COG3943@2|Bacteria,2IA5J@201174|Actinobacteria	201174|Actinobacteria	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
YHH2_k127_3895080_16	580332.Slit_2742	1.957e-120	390.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria,44VFS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH2_k127_3895080_7	580332.Slit_2274	4.209e-153	496.0	28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,2VPIS@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3895080_18	580332.Slit_2273	2.409e-94	310.0	2DS8H@1|root,32USH@2|Bacteria,1RCDN@1224|Proteobacteria,2W06A@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
YHH2_k127_3895080_15	580332.Slit_2733	2.913e-127	409.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria,44VEN@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A,Sugar-bind
YHH2_k127_3895080_11	580332.Slit_2732	3.128e-132	423.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,44UZR@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
YHH2_k127_3895080_2	580332.Slit_2731	6.661e-239	746.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,44V08@713636|Nitrosomonadales	28216|Betaproteobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
YHH2_k127_3895080_36	1328313.DS2_07158	9.819e-07	52.0	2E9J1@1|root,333RY@2|Bacteria,1NCU6@1224|Proteobacteria,1SF5Y@1236|Gammaproteobacteria,468B7@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_39014_6	439235.Dalk_1258	1.439e-124	414.0	COG2114@1|root,COG2703@1|root,COG2114@2|Bacteria,COG2703@2|Bacteria,1MW5Z@1224|Proteobacteria,42RM8@68525|delta/epsilon subdivisions,2WNZ4@28221|Deltaproteobacteria,2MKKN@213118|Desulfobacterales	28221|Deltaproteobacteria	PT	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Guanylate_cyc,Hemerythrin
YHH2_k127_39014_1	580332.Slit_2509	9.681e-255	790.0	28HIY@1|root,2Z7U8@2|Bacteria,1MY3K@1224|Proteobacteria,2VKE4@28216|Betaproteobacteria,44V51@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_39014_2	395494.Galf_0469	1.16e-238	747.0	COG2703@1|root,COG3437@1|root,COG2703@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,44VG5@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	DUF3369,HD,HD_5,Response_reg
YHH2_k127_39014_15	580332.Slit_1238	7.296e-33	130.0	2CIC4@1|root,3328Z@2|Bacteria,1N7FS@1224|Proteobacteria,2VX81@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_39014_3	580332.Slit_1243	4.119e-229	712.0	28IVT@1|root,2Z8U5@2|Bacteria,1R7G9@1224|Proteobacteria,2W17G@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_39014_13	1121035.AUCH01000007_gene434	2.516e-44	162.0	2ED9V@1|root,33769@2|Bacteria,1N87Z@1224|Proteobacteria,2W3PP@28216|Betaproteobacteria,2KZ35@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
YHH2_k127_39014_7	640081.Dsui_3351	4.061e-115	385.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2VMKA@28216|Betaproteobacteria,2KW8I@206389|Rhodocyclales	206389|Rhodocyclales	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
YHH2_k127_39014_8	640081.Dsui_3352	3.915e-62	221.0	COG0664@1|root,COG0664@2|Bacteria,1RJU7@1224|Proteobacteria,2VZHQ@28216|Betaproteobacteria,2KYES@206389|Rhodocyclales	206389|Rhodocyclales	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YHH2_k127_39014_12	472759.Nhal_0817	1.51e-45	175.0	2DC00@1|root,2ZC4V@2|Bacteria,1RBPR@1224|Proteobacteria,1S2KT@1236|Gammaproteobacteria,1X0Y7@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_39014_14	580332.Slit_1244	1.995e-36	138.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria,44W19@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
YHH2_k127_39014_11	1163617.SCD_n00583	4.995e-49	176.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
YHH2_k127_39014_5	1100721.ALKO01000027_gene371	2.219e-156	501.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2VK9X@28216|Betaproteobacteria,4ABVQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
YHH2_k127_39014_0	580332.Slit_1384	0.0	1146.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VP66@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH2_k127_39014_9	1163617.SCD_n02545	3.375e-58	213.0	2ANXW@1|root,31DYS@2|Bacteria,1MYQS@1224|Proteobacteria,2VTPU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_39014_4	580332.Slit_1386	2.862e-202	633.0	COG0348@1|root,COG0348@2|Bacteria,1PX8Q@1224|Proteobacteria,2WCR5@28216|Betaproteobacteria,44WIQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
YHH2_k127_39014_10	580332.Slit_1387	9.198e-54	190.0	COG4232@1|root,COG4232@2|Bacteria,1N8UG@1224|Proteobacteria,2VSTK@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
YHH2_k127_3924534_16	580332.Slit_0708	2.596e-17	81.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,44VEJ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
YHH2_k127_3924534_1	580332.Slit_1657	0.0	1159.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,44V6R@713636|Nitrosomonadales	28216|Betaproteobacteria	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
YHH2_k127_3924534_6	697282.Mettu_4312	8.84e-168	535.0	COG3287@1|root,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,1RY7N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	GfdT protein	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
YHH2_k127_3924534_12	395494.Galf_1378	1.603e-65	237.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,2VK9Q@28216|Betaproteobacteria,44WPJ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,PAS_9,SnoaL_3
YHH2_k127_3924534_11	1328313.DS2_08605	4.32e-82	287.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,465AJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YHH2_k127_3924534_8	1266925.JHVX01000001_gene2458	3.391e-104	344.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria,371VD@32003|Nitrosomonadales	28216|Betaproteobacteria	K	SMART cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
YHH2_k127_3924534_10	697282.Mettu_0564	2.13e-89	304.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,1RP0B@1236|Gammaproteobacteria,1XDPT@135618|Methylococcales	135618|Methylococcales	K	SMART HTH transcriptional regulator, Crp	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
YHH2_k127_3924534_15	1121035.AUCH01000001_gene1980	3.441e-21	100.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria,2KUKV@206389|Rhodocyclales	206389|Rhodocyclales	K	RNA polymerase sigma	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH2_k127_3924534_0	395494.Galf_2062	0.0	1263.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	2.7.13.3,3.1.3.3	ko:K07315,ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	EAL,GAF_2,GGDEF,HATPase_c,HisKA_2,HisKA_3,PAS_3,PAS_4,PAS_8,PAS_9,SpoIIE,dCache_1
YHH2_k127_3924534_9	395494.Galf_2061	2.138e-101	333.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VQ9H@28216|Betaproteobacteria,44VRB@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_3924534_19	398578.Daci_0283	6.479e-10	63.0	COG1396@1|root,COG1396@2|Bacteria,1NGFD@1224|Proteobacteria,2VY3S@28216|Betaproteobacteria,4AIIH@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulator, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
YHH2_k127_3924534_7	1500894.JQNN01000001_gene4237	3.325e-116	388.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,2VSQ2@28216|Betaproteobacteria,474N5@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Pfam:HipA_N	-	-	-	-	-	-	-	-	-	-	-	-	Couple_hipA,HipA_C
YHH2_k127_3924534_18	1408164.MOLA814_00668	2.197e-12	68.0	2EC5K@1|root,33649@2|Bacteria,1NFQP@1224|Proteobacteria,2VXQY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3924534_3	1217656.F964_01736	2.82e-269	873.0	2ECF1@1|root,336D8@2|Bacteria,1N9VY@1224|Proteobacteria,1SKBC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3924534_4	580332.Slit_1655	1.535e-212	667.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VJVZ@28216|Betaproteobacteria,44W4C@713636|Nitrosomonadales	28216|Betaproteobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
YHH2_k127_3924534_17	1089553.Tph_c06220	9.413e-15	79.0	COG1848@1|root,COG1848@2|Bacteria,1V9QN@1239|Firmicutes,24U45@186801|Clostridia	186801|Clostridia	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_3924534_5	580332.Slit_2804	3.278e-187	606.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria,2VNJ7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_9,dCache_1
YHH2_k127_3924534_2	580332.Slit_1654	1.512e-290	899.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,44V57@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
YHH2_k127_3924534_13	580332.Slit_1003	2.357e-56	199.0	2DX2X@1|root,32V2M@2|Bacteria,1MZZC@1224|Proteobacteria,2VU2H@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3924722_0	580332.Slit_0479	6.677e-253	786.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria,44W65@713636|Nitrosomonadales	28216|Betaproteobacteria	P	MgtE intracellular N domain	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
YHH2_k127_3925271_2	1288494.EBAPG3_1700	4.901e-199	643.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1QP3Z@1224|Proteobacteria,2VI9V@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Eco57I restriction-modification methylase	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I
YHH2_k127_3925271_5	1173020.Cha6605_2710	1.215e-33	135.0	COG1487@1|root,COG1487@2|Bacteria,1G6RD@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH2_k127_3925271_0	1288494.EBAPG3_1690	0.0	1147.0	COG0553@1|root,COG0553@2|Bacteria,1NC5H@1224|Proteobacteria,2VJXT@28216|Betaproteobacteria,374KA@32003|Nitrosomonadales	28216|Betaproteobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH2_k127_3925271_1	1288494.EBAPG3_1690	2.986e-261	808.0	COG0553@1|root,COG0553@2|Bacteria,1NC5H@1224|Proteobacteria,2VJXT@28216|Betaproteobacteria,374KA@32003|Nitrosomonadales	28216|Betaproteobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH2_k127_3925271_7	697282.Mettu_3274	5.269e-12	70.0	COG3514@1|root,COG3514@2|Bacteria,1NMDA@1224|Proteobacteria,1SI7C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
YHH2_k127_3925271_6	459495.SPLC1_S411620	7.121e-22	98.0	COG2929@1|root,COG2929@2|Bacteria,1G805@1117|Cyanobacteria,1HCPF@1150|Oscillatoriales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_3925271_4	261292.Nit79A3_0695	1.258e-42	158.0	2E588@1|root,3300P@2|Bacteria,1N79I@1224|Proteobacteria,2W3RS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF5062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5062
YHH2_k127_3925271_3	580332.Slit_2071	8.355e-143	467.0	COG2114@1|root,COG2703@1|root,COG2114@2|Bacteria,COG2703@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,44WAE@713636|Nitrosomonadales	28216|Betaproteobacteria	PT	SMART adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
YHH2_k127_3925650_3	580332.Slit_0323	2.295e-142	475.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3925650_4	1163617.SCD_n00427	2.607e-38	145.0	2E8HY@1|root,332W0@2|Bacteria,1N9SS@1224|Proteobacteria,2W4P0@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3925650_5	395494.Galf_0358	9.254e-24	103.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,2VXFA@28216|Betaproteobacteria,44W38@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SlyX	-	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
YHH2_k127_3925650_0	330214.NIDE2620	0.0	1142.0	COG4096@1|root,COG4096@2|Bacteria,3J18J@40117|Nitrospirae	2|Bacteria	L	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
YHH2_k127_3925650_1	589865.DaAHT2_1600	9.342e-248	774.0	COG2865@1|root,COG2865@2|Bacteria,1MXG1@1224|Proteobacteria,42M7P@68525|delta/epsilon subdivisions,2WKGM@28221|Deltaproteobacteria,2MITW@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
YHH2_k127_3925650_2	1348657.M622_19050	2.516e-146	467.0	COG3645@1|root,COG3645@2|Bacteria,1MVMT@1224|Proteobacteria,2WBCB@28216|Betaproteobacteria,2KZ2E@206389|Rhodocyclales	206389|Rhodocyclales	S	DNA-damage-inducible protein d	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3941483_15	62928.azo2883	1.265e-25	106.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2VVS2@28216|Betaproteobacteria,2KX8R@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
YHH2_k127_3941483_0	580332.Slit_2743	5.106e-297	915.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,44UZX@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
YHH2_k127_3941483_3	580332.Slit_0805	1.143e-176	556.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VJE9@28216|Betaproteobacteria,44W7X@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	NifU-like domain	-	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
YHH2_k127_3941483_1	580332.Slit_0806	1.961e-239	744.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VNE4@28216|Betaproteobacteria,44WC3@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Beta-eliminating lyase	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5,Rhodanese
YHH2_k127_3941483_2	580332.Slit_0807	1.689e-203	637.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VIRD@28216|Betaproteobacteria,44WCU@713636|Nitrosomonadales	28216|Betaproteobacteria	E	HMGL-like	nifV	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
YHH2_k127_3941483_4	1485544.JQKP01000001_gene984	3.92e-144	462.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VMGF@28216|Betaproteobacteria,44WCG@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	nifP	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
YHH2_k127_3941483_6	580332.Slit_0809	1.536e-79	268.0	COG0457@1|root,COG0457@2|Bacteria,1R714@1224|Proteobacteria,2VRZB@28216|Betaproteobacteria,44WD3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3941483_12	580332.Slit_0810	1.552e-49	178.0	2E67S@1|root,330W8@2|Bacteria,1NA3E@1224|Proteobacteria,2VX71@28216|Betaproteobacteria,44WGB@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Nitrogen fixation protein NifW	nifW	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
YHH2_k127_3941483_7	580332.Slit_0811	2.373e-78	264.0	COG0760@1|root,COG0760@2|Bacteria,1QUCX@1224|Proteobacteria,2WGPH@28216|Betaproteobacteria,44WFU@713636|Nitrosomonadales	28216|Betaproteobacteria	O	NifZ domain	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
YHH2_k127_3941483_5	580332.Slit_0812	1.322e-132	427.0	COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,2VQ5A@28216|Betaproteobacteria,44W6F@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase
YHH2_k127_3941483_13	395494.Galf_2191	3.543e-48	174.0	COG5606@1|root,COG5606@2|Bacteria,1RKMM@1224|Proteobacteria,2VV7X@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
YHH2_k127_3941483_8	1502770.JQMG01000001_gene232	8.061e-78	268.0	2BNRQ@1|root,32HF7@2|Bacteria,1PA1V@1224|Proteobacteria,2VQ4V@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH2_k127_3941483_10	1502770.JQMG01000001_gene233	1.337e-68	236.0	COG1395@1|root,COG1395@2|Bacteria	2|Bacteria	K	domain, Protein	bldD	-	-	ko:K07110,ko:K21572	-	-	-	-	ko00000,ko02000,ko03000	8.A.46.1,8.A.46.3	-	-	HTH_3,HTH_31
YHH2_k127_3941483_14	339670.Bamb_5438	3.485e-37	144.0	COG1476@1|root,COG1476@2|Bacteria,1QVBH@1224|Proteobacteria,2WH32@28216|Betaproteobacteria,1K9HS@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
YHH2_k127_3941483_9	196367.JNFG01000202_gene2627	1.222e-69	241.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2VNYW@28216|Betaproteobacteria,1K78V@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
YHH2_k127_4000485_1	857087.Metme_1468	1.116e-56	199.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XDPG@135618|Methylococcales	135618|Methylococcales	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH2_k127_4000485_0	640510.BC1001_2034	1.121e-127	415.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2VI1H@28216|Betaproteobacteria,1K3UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
YHH2_k127_4000485_2	391735.Veis_3672	4.927e-15	74.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,2VTY4@28216|Betaproteobacteria,4AFP7@80864|Comamonadaceae	28216|Betaproteobacteria	K	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
YHH2_k127_4020871_13	1121937.AUHJ01000024_gene67	1.078e-70	243.0	COG3177@1|root,COG3177@2|Bacteria,1MX0V@1224|Proteobacteria,1RQYT@1236|Gammaproteobacteria,465WD@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH2_k127_4020871_20	1454004.AW11_00250	2.609e-24	105.0	2EJDA@1|root,33D4B@2|Bacteria,1NJG2@1224|Proteobacteria,2VXQP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4020871_0	580332.Slit_2490	0.0	1193.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,44W9F@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sodium:solute symporter family	actP_1	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
YHH2_k127_4020871_16	580332.Slit_2491	1.778e-41	154.0	COG4327@1|root,COG4327@2|Bacteria,1PDE2@1224|Proteobacteria,2VW4R@28216|Betaproteobacteria,44WJQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
YHH2_k127_4020871_4	580332.Slit_2492	8.032e-131	419.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,44WD1@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	basR_3	-	-	ko:K02483,ko:K07666,ko:K07774	ko02020,ko02024,map02020,map02024	M00453,M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_4020871_3	580332.Slit_2493	5.102e-239	744.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,2VI80@28216|Betaproteobacteria,44VQI@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
YHH2_k127_4020871_2	580332.Slit_2768	1.044e-280	871.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2W9SN@28216|Betaproteobacteria,44WNI@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM cytochrome c biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
YHH2_k127_4020871_8	580332.Slit_2769	1.363e-92	306.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,44VWV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
YHH2_k127_4020871_6	580332.Slit_2770	1.471e-98	329.0	2B96M@1|root,322HU@2|Bacteria,1RIIU@1224|Proteobacteria,2VT7Z@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FecR
YHH2_k127_4020871_7	1163617.SCD_n02615	1.058e-97	322.0	COG0225@1|root,COG0225@2|Bacteria,1NC84@1224|Proteobacteria,2VKZ6@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA2	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
YHH2_k127_4020871_10	580332.Slit_2771	4.486e-83	279.0	COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,2VRBF@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE9	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_4020871_9	580332.Slit_2772	2.11e-92	307.0	COG4944@1|root,COG4944@2|Bacteria	2|Bacteria	K	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
YHH2_k127_4020871_24	870187.Thini_2840	2.531e-05	53.0	COG1396@1|root,COG1396@2|Bacteria,1NIMT@1224|Proteobacteria,1SH5G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
YHH2_k127_4020871_17	1408164.MOLA814_00664	2.071e-27	121.0	2DP5C@1|root,330KK@2|Bacteria,1NBY3@1224|Proteobacteria	1224|Proteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH2_k127_4020871_19	545694.TREPR_2122	1.124e-24	107.0	COG1708@1|root,COG1708@2|Bacteria,2JB39@203691|Spirochaetes	203691|Spirochaetes	L	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH2_k127_4020871_15	545694.TREPR_2123	2.571e-44	166.0	29XQP@1|root,30JGD@2|Bacteria,2JB3F@203691|Spirochaetes	203691|Spirochaetes	H	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
YHH2_k127_4020871_21	1146883.BLASA_3958	2.734e-20	94.0	COG2337@1|root,COG2337@2|Bacteria,2IICB@201174|Actinobacteria	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH2_k127_4020871_12	1121104.AQXH01000001_gene1307	2.766e-75	290.0	COG1361@1|root,COG2304@1|root,COG2931@1|root,COG3420@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria,COG4932@2|Bacteria,4NMB8@976|Bacteroidetes,1IQMS@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,SdrD_B
YHH2_k127_4020871_25	1396.DJ87_5671	6.067e-05	58.0	COG1361@1|root,COG1361@2|Bacteria,1UQ5B@1239|Firmicutes,4IPKB@91061|Bacilli,1ZMEB@1386|Bacillus	91061|Bacilli	M	conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH2_k127_4020871_14	1337093.MBE-LCI_3444	5.454e-46	194.0	COG1361@1|root,COG1361@2|Bacteria,1R59C@1224|Proteobacteria,2TUS0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH2_k127_4020871_22	1170562.Cal6303_3949	2.654e-14	84.0	COG2885@1|root,COG2885@2|Bacteria,1G1SI@1117|Cyanobacteria,1HQN9@1161|Nostocales	1117|Cyanobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,OmpA
YHH2_k127_4020871_1	365044.Pnap_0406	0.0	1072.0	COG1470@1|root,COG1520@1|root,COG3188@1|root,COG1470@2|Bacteria,COG1520@2|Bacteria,COG3188@2|Bacteria,1QV71@1224|Proteobacteria,2VKHC@28216|Betaproteobacteria,4AGE2@80864|Comamonadaceae	28216|Betaproteobacteria	NU	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH2_k127_4020871_5	794903.OPIT5_20785	1.226e-119	418.0	COG1361@1|root,COG1361@2|Bacteria,46Z97@74201|Verrucomicrobia,3K8F8@414999|Opitutae	414999|Opitutae	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH2_k127_4020871_18	365044.Pnap_0404	8.052e-27	116.0	COG4719@1|root,COG4719@2|Bacteria,1MZ71@1224|Proteobacteria,2VVMB@28216|Betaproteobacteria,4AHXQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH2_k127_4020871_11	29581.BW37_03396	2.22e-76	262.0	COG0745@1|root,COG0745@2|Bacteria,1MZQA@1224|Proteobacteria,2WBEJ@28216|Betaproteobacteria,475NH@75682|Oxalobacteraceae	28216|Betaproteobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_4068477_7	1538295.JY96_21655	5.071e-35	137.0	COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,2VRES@28216|Betaproteobacteria,1KM0T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_4068477_11	555088.DealDRAFT_1186	8.166e-10	61.0	COG5450@1|root,COG5450@2|Bacteria,1VIXD@1239|Firmicutes,24S96@186801|Clostridia	186801|Clostridia	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
YHH2_k127_4068477_8	743299.Acife_3122	6.729e-24	107.0	COG4453@1|root,COG4453@2|Bacteria,1NFP8@1224|Proteobacteria,1SEJE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
YHH2_k127_4068477_5	743299.Acife_3123	4.773e-61	214.0	COG0454@1|root,COG0454@2|Bacteria,1R17C@1224|Proteobacteria,1T4VP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4068477_2	1163617.SCD_n01014	1.694e-150	478.0	COG3440@1|root,COG3440@2|Bacteria,1N4JP@1224|Proteobacteria,2VVU0@28216|Betaproteobacteria	28216|Betaproteobacteria	V	HNH endonuclease	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
YHH2_k127_4068477_9	1215092.PA6_047_00130	1.394e-14	76.0	COG0560@1|root,COG0560@2|Bacteria,1R6HK@1224|Proteobacteria,1S00M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
YHH2_k127_4068477_1	76114.ebA65	2.29e-176	557.0	COG3177@1|root,COG3177@2|Bacteria,1MWAU@1224|Proteobacteria,2VH5G@28216|Betaproteobacteria,2KXZ2@206389|Rhodocyclales	206389|Rhodocyclales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH2_k127_4068477_10	1485544.JQKP01000002_gene1484	1.412e-10	63.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,44VN2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
YHH2_k127_4068477_0	1123256.KB907926_gene804	0.0	1093.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X3JU@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YHH2_k127_4068477_4	1123256.KB907926_gene803	7.978e-64	233.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,1RQ67@1236|Gammaproteobacteria,1XA98@135614|Xanthomonadales	135614|Xanthomonadales	M	Biotin-lipoyl like	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
YHH2_k127_4068477_3	1123368.AUIS01000028_gene1310	2.289e-71	256.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,1S4SH@1236|Gammaproteobacteria,2NCF7@225057|Acidithiobacillales	225057|Acidithiobacillales	MU	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH2_k127_4125344_21	1121035.AUCH01000014_gene2479	1.256e-23	109.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria,2KWDE@206389|Rhodocyclales	206389|Rhodocyclales	H	molybdopterin-guanine dinucleotide biosynthesis protein	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
YHH2_k127_4125344_8	1485544.JQKP01000011_gene766	5.569e-102	336.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,44VAY@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YHH2_k127_4125344_23	1485544.JQKP01000011_gene767	1.01e-19	92.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,44W0W@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
YHH2_k127_4125344_20	395494.Galf_0441	2.671e-24	104.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,44W2X@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
YHH2_k127_4125344_3	1485544.JQKP01000004_gene472	2.996e-201	632.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,44V7W@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
YHH2_k127_4125344_12	857087.Metme_0429	4.277e-61	218.0	COG2337@1|root,COG2337@2|Bacteria,1PVJ9@1224|Proteobacteria,1TM47@1236|Gammaproteobacteria,1XGTH@135618|Methylococcales	135618|Methylococcales	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH2_k127_4125344_17	857087.Metme_0430	2.117e-30	122.0	COG2336@1|root,COG2336@2|Bacteria,1N7DX@1224|Proteobacteria,1STBB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_4125344_22	1123399.AQVE01000001_gene562	9.614e-22	98.0	COG4634@1|root,COG4634@2|Bacteria,1N9QC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
YHH2_k127_4125344_19	278957.ABEA03000213_gene3795	1.873e-26	110.0	COG2442@1|root,COG2442@2|Bacteria,46YPW@74201|Verrucomicrobia,3K9YX@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YHH2_k127_4125344_0	580332.Slit_0164	4.805e-282	879.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,44VGW@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Soluble lytic murein transglycosylase L domain	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
YHH2_k127_4125344_1	580332.Slit_0165	2.662e-228	711.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,44V0A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Probable RNA and SrmB- binding site of polymerase A	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
YHH2_k127_4125344_13	1209072.ALBT01000065_gene1145	2.877e-52	198.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,1FI2Y@10|Cellvibrio	1236|Gammaproteobacteria	T	MASE2 domain	adrA	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621	2.7.7.65	ko:K18968	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko02000	9.B.34.1.2	-	iECSF_1327.ECSF_0346,ic_1306.c0492	GGDEF,MASE2
YHH2_k127_4125344_11	580332.Slit_0166	1.56e-72	248.0	COG3663@1|root,COG3663@2|Bacteria,1REPV@1224|Proteobacteria,2VRAT@28216|Betaproteobacteria,44WHS@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Uracil DNA glycosylase superfamily	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH2_k127_4125344_2	580332.Slit_0167	5.948e-203	639.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,44V36@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
YHH2_k127_4125344_6	580332.Slit_0168	3.349e-133	427.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,44VK9@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.100,1.5.1.33	ko:K00059,ko:K03793	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH2_k127_4125344_4	580332.Slit_0169	1.279e-171	540.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,44VEK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
YHH2_k127_4125344_10	580332.Slit_0171	5.541e-82	275.0	COG2731@1|root,COG2731@2|Bacteria,1RJ5F@1224|Proteobacteria,2VTSG@28216|Betaproteobacteria,44VXN@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
YHH2_k127_4125344_15	1045855.DSC_04005	2.534e-44	169.0	2AAVV@1|root,3108W@2|Bacteria,1PN9A@1224|Proteobacteria,1TBWX@1236|Gammaproteobacteria,1X7A9@135614|Xanthomonadales	135614|Xanthomonadales	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
YHH2_k127_4125344_18	1123296.JQKE01000125_gene1440	2.367e-27	113.0	COG5606@1|root,COG5606@2|Bacteria,1NA3S@1224|Proteobacteria,2WFPX@28216|Betaproteobacteria,2KTW8@206351|Neisseriales	206351|Neisseriales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
YHH2_k127_4125344_16	360910.BAV0467	4.709e-38	150.0	COG0671@1|root,COG0671@2|Bacteria,1NZWW@1224|Proteobacteria	1224|Proteobacteria	I	phosphoesterase, PA-phosphatase related	-	-	-	ko:K12977	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	PAP2
YHH2_k127_4125344_5	1208321.D104_10895	2.532e-162	527.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria,1XMGT@135619|Oceanospirillales	135619|Oceanospirillales	S	PFAM sulfatase	-	-	2.7.8.43	ko:K03760,ko:K19353	ko00540,ko01503,map00540,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
YHH2_k127_4125344_14	1502770.JQMG01000001_gene1634	2.967e-47	177.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VTH4@28216|Betaproteobacteria,2KMXG@206350|Nitrosomonadales	206350|Nitrosomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
YHH2_k127_4125344_7	640081.Dsui_3035	2.525e-110	369.0	COG2199@1|root,COG3706@2|Bacteria,1N7HG@1224|Proteobacteria,2VPE2@28216|Betaproteobacteria,2KUP8@206389|Rhodocyclales	206389|Rhodocyclales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
YHH2_k127_4125344_9	580332.Slit_0172	6.467e-96	316.0	COG3038@1|root,COG3038@2|Bacteria,1RBP8@1224|Proteobacteria,2VQWK@28216|Betaproteobacteria,44W0C@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Prokaryotic cytochrome b561	yodB	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
YHH2_k127_4125344_24	1331060.RLDS_11260	5.574e-18	83.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_413462_3	349521.HCH_03415	1.01e-129	422.0	COG0464@1|root,COG0464@2|Bacteria,1MVVP@1224|Proteobacteria,1RY8X@1236|Gammaproteobacteria,1XJY0@135619|Oceanospirillales	135619|Oceanospirillales	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
YHH2_k127_413462_0	349521.HCH_03413	5.287e-304	953.0	COG1404@1|root,COG1404@2|Bacteria,1ND93@1224|Proteobacteria,1RZ0J@1236|Gammaproteobacteria,1XME5@135619|Oceanospirillales	135619|Oceanospirillales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH2_k127_413462_5	876044.IMCC3088_1227	1.67e-14	75.0	COG4456@1|root,COG4456@2|Bacteria,1N85E@1224|Proteobacteria,1SE5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_413462_2	580332.Slit_1133	1.866e-138	450.0	COG0845@1|root,COG0845@2|Bacteria,1MV1R@1224|Proteobacteria,2VHJC@28216|Betaproteobacteria,44WE6@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
YHH2_k127_413462_1	580332.Slit_1134	4.534e-217	678.0	COG0577@1|root,COG0577@2|Bacteria,1MVSU@1224|Proteobacteria,2VKTK@28216|Betaproteobacteria,44W6X@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_413462_4	580332.Slit_1135	1.021e-77	261.0	COG1136@1|root,COG1136@2|Bacteria,1MXVW@1224|Proteobacteria,2VI95@28216|Betaproteobacteria,44W8E@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_4155350_12	765911.Thivi_2664	4.447e-28	114.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria,1SHHY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
YHH2_k127_4155350_10	1454004.AW11_01193	3.856e-48	199.0	COG1864@1|root,COG2931@1|root,COG3179@1|root,COG3209@1|root,COG3391@1|root,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3179@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,1RC1P@1224|Proteobacteria,2VUZC@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19
YHH2_k127_4155350_4	580332.Slit_1798	3.417e-105	344.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,44V0F@713636|Nitrosomonadales	28216|Betaproteobacteria	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
YHH2_k127_4155350_3	580332.Slit_1797	1.69e-112	368.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,44VAM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
YHH2_k127_4155350_2	580332.Slit_1796	1.045e-137	441.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,44VN4@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
YHH2_k127_4155350_13	580332.Slit_1795	5.752e-19	87.0	COG3114@1|root,COG3114@2|Bacteria	2|Bacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmD	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735	CcmD
YHH2_k127_4155350_7	580332.Slit_1794	2.756e-70	241.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,44VV9@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
YHH2_k127_4155350_0	580332.Slit_1793	0.0	1113.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,44VEM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
YHH2_k127_4155350_5	1485544.JQKP01000007_gene1988	5.677e-86	287.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,44VSS@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
YHH2_k127_4155350_9	395494.Galf_1766	2.079e-58	209.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,44VXQ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Cytochrome C biogenesis protein	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
YHH2_k127_4155350_1	580332.Slit_1790	6.424e-145	470.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,44V8W@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcmI	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
YHH2_k127_4155350_6	637390.AFOH01000137_gene1778	2.66e-72	246.0	COG5611@1|root,COG5611@2|Bacteria,1RDUI@1224|Proteobacteria,1S7Z8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_4155350_11	743299.Acife_0180	3.96e-38	143.0	COG2002@1|root,COG2002@2|Bacteria,1P39F@1224|Proteobacteria,1SS8B@1236|Gammaproteobacteria,2NDXQ@225057|Acidithiobacillales	225057|Acidithiobacillales	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
YHH2_k127_4155350_14	1485544.JQKP01000001_gene1107	2.365e-09	59.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,44V4T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
YHH2_k127_4155350_8	580332.Slit_2191	8.438e-65	223.0	2CZS8@1|root,32T71@2|Bacteria,1N4G2@1224|Proteobacteria,2VUSW@28216|Betaproteobacteria,44WJV@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4190519_4	580332.Slit_0649	1.772e-64	222.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,44VB2@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Sigma-70 factor, region 1.2	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
YHH2_k127_4190519_5	580332.Slit_2372	1.768e-50	183.0	COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,2VVCK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
YHH2_k127_4190519_2	580332.Slit_2371	6.754e-152	493.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,44VHS@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
YHH2_k127_4190519_3	580332.Slit_2370	2.332e-131	420.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2VINI@28216|Betaproteobacteria,44VG7@713636|Nitrosomonadales	28216|Betaproteobacteria	D	TIGRFAM cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
YHH2_k127_4190519_1	580332.Slit_2369	1.223e-162	529.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,44V41@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
YHH2_k127_4190519_0	580332.Slit_2368	9.508e-216	678.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,44VBT@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH2_k127_4204719_1	713586.KB900536_gene753	3.122e-88	297.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1WWXT@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_4204719_2	330214.NIDE1755	7.224e-88	295.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH2_k127_4204719_0	580332.Slit_0145	3.046e-203	644.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,44UYU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
YHH2_k127_4204719_3	395494.Galf_2688	2.572e-42	155.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,44VAD@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH2_k127_4262384_1	580332.Slit_1994	7.904e-72	246.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,44VHZ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
YHH2_k127_4262384_0	580332.Slit_1993	1.061e-72	247.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,44VTM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YHH2_k127_4262384_2	398767.Glov_0642	7.774e-21	108.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
YHH2_k127_4320328_7	261292.Nit79A3_2157	3.775e-07	54.0	COG3549@1|root,COG3549@2|Bacteria,1PU0N@1224|Proteobacteria,2W39Q@28216|Betaproteobacteria,374FE@32003|Nitrosomonadales	28216|Betaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
YHH2_k127_4320328_5	261292.Nit79A3_2158	1.985e-41	154.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
YHH2_k127_4320328_1	580332.Slit_0071	5.575e-171	538.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2VIXE@28216|Betaproteobacteria,44UYK@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
YHH2_k127_4320328_3	156889.Mmc1_1387	3.312e-72	256.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
YHH2_k127_4320328_0	292415.Tbd_0241	7.719e-222	696.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,1KRHZ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
YHH2_k127_4320328_4	580332.Slit_0065	4.154e-64	220.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,44VUX@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
YHH2_k127_4320328_2	1000565.METUNv1_03322	1.5e-101	335.0	2C5U9@1|root,30FF7@2|Bacteria,1N2U0@1224|Proteobacteria,2VSBN@28216|Betaproteobacteria,2KWHS@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
YHH2_k127_4320686_4	580332.Slit_2231	1.24e-53	190.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,44VGQ@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
YHH2_k127_4320686_2	580332.Slit_2230	2.822e-82	274.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,44VPY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
YHH2_k127_4320686_1	1123393.KB891316_gene1905	3.799e-85	286.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2VK3P@28216|Betaproteobacteria,1KSG2@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
YHH2_k127_4320686_0	1283284.AZUK01000006_gene3071	1.758e-117	381.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,1S2TQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
YHH2_k127_4320686_3	580332.Slit_2229	7.181e-79	268.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,44VJ8@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
YHH2_k127_4353712_0	292415.Tbd_0872	3.704e-290	893.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,2VHJ5@28216|Betaproteobacteria,1KS3F@119069|Hydrogenophilales	119069|Hydrogenophilales	C	FAD binding domain	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
YHH2_k127_4353712_12	1163617.SCD_n01728	4.804e-112	369.0	COG0727@1|root,COG0727@2|Bacteria,1R3YG@1224|Proteobacteria,2W1RG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
YHH2_k127_4353712_10	580332.Slit_1445	5.294e-143	460.0	2CIBN@1|root,2Z8JT@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
YHH2_k127_4353712_9	580332.Slit_1444	1.517e-149	477.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,2VQEZ@28216|Betaproteobacteria,44VH6@713636|Nitrosomonadales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH2_k127_4353712_1	580332.Slit_1443	5.108e-220	687.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VIEP@28216|Betaproteobacteria,44VP4@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	dapC	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_4353712_5	580332.Slit_1442	1.024e-167	531.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,44VFW@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
YHH2_k127_4353712_3	580332.Slit_1441	1.668e-196	619.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,44W5Q@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	pilT2	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH2_k127_4353712_2	580332.Slit_1439	5.267e-214	669.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,44VKT@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
YHH2_k127_4353712_7	580332.Slit_1438	5.464e-158	501.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria,44VM3@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
YHH2_k127_4353712_6	1504672.669785368	2.719e-164	525.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,2VNBM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
YHH2_k127_4353712_13	765911.Thivi_4339	2.023e-92	308.0	arCOG06916@1|root,30456@2|Bacteria,1R83C@1224|Proteobacteria,1RQ5P@1236|Gammaproteobacteria,1X15M@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4276
YHH2_k127_4353712_11	580332.Slit_1437	8.196e-143	456.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,44VE7@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Squalene/phytoene synthase	hpnC	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
YHH2_k127_4353712_15	1485544.JQKP01000017_gene608	2.49e-25	108.0	2BSS5@1|root,32MV6@2|Bacteria,1PJWZ@1224|Proteobacteria,2W88S@28216|Betaproteobacteria,44WJU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH2_k127_4353712_8	580332.Slit_1436	8.853e-151	480.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,44V7C@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Squalene/phytoene synthase	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
YHH2_k127_4353712_4	580332.Slit_1435	2.283e-196	621.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,44V02@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin containing amine oxidoreductase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
YHH2_k127_4353712_16	1123400.KB904757_gene2184	3.443e-21	95.0	COG2002@1|root,COG2002@2|Bacteria,1NGQ4@1224|Proteobacteria,1SGRE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
YHH2_k127_4353712_14	998674.ATTE01000001_gene848	2.71e-39	150.0	COG4374@1|root,COG4374@2|Bacteria,1N7EF@1224|Proteobacteria,1SCM0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_4413953_0	1485544.JQKP01000005_gene382	1.099e-299	932.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,44VF6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YHH2_k127_4485936_7	580332.Slit_1687	6.801e-29	116.0	2EMP6@1|root,33FBM@2|Bacteria,1NGBE@1224|Proteobacteria,2VYCB@28216|Betaproteobacteria,44WK7@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4485936_0	580332.Slit_1686	2.562e-268	829.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,2VPWJ@28216|Betaproteobacteria,44W8G@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
YHH2_k127_4485936_1	580332.Slit_1685	1.061e-238	738.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,2VPBV@28216|Betaproteobacteria,44WDK@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
YHH2_k127_4485936_3	580332.Slit_1684	1.769e-71	243.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,2VR8N@28216|Betaproteobacteria,44WFW@713636|Nitrosomonadales	28216|Betaproteobacteria	P	DsrE/DsrF-like family	-	-	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
YHH2_k127_4485936_4	580332.Slit_1683	5.079e-66	226.0	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,2VSQ5@28216|Betaproteobacteria,44WHC@713636|Nitrosomonadales	28216|Betaproteobacteria	P	DsrE/DsrF-like family	-	-	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
YHH2_k127_4485936_6	580332.Slit_1682	3.137e-44	162.0	COG2168@1|root,COG2168@2|Bacteria,1PTT8@1224|Proteobacteria,2VWF4@28216|Betaproteobacteria,44WHZ@713636|Nitrosomonadales	28216|Betaproteobacteria	P	DsrH like protein	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
YHH2_k127_4485936_5	580332.Slit_1681	5.04e-65	222.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2VSFJ@28216|Betaproteobacteria,44WGQ@713636|Nitrosomonadales	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
YHH2_k127_4485936_2	580332.Slit_1680	4.156e-113	368.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria,44W95@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
YHH2_k127_4544846_0	580332.Slit_0462	9.474e-180	570.0	COG0477@1|root,COG0477@2|Bacteria,1QUAG@1224|Proteobacteria,2WHA4@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08227	-	-	-	-	ko00000,ko02000	2.A.1.42	-	-	MFS_1
YHH2_k127_4544846_2	1124991.MU9_1953	1.389e-06	53.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,1RNGS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
YHH2_k127_4724624_1	580332.Slit_0430	5.475e-80	269.0	COG4769@1|root,COG4769@2|Bacteria,1RJIB@1224|Proteobacteria,2VRM1@28216|Betaproteobacteria,44VVI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
YHH2_k127_4724624_0	580332.Slit_0429	9.385e-115	372.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,44VAK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
YHH2_k127_475420_3	580332.Slit_1660	4.826e-60	213.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44VC4@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DEAD DEAH box helicase domain protein	rhlE1	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
YHH2_k127_475420_4	62928.azo1372	5.178e-08	57.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_475420_2	1304883.KI912532_gene2065	6.194e-119	389.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2VMEV@28216|Betaproteobacteria,2KVW6@206389|Rhodocyclales	206389|Rhodocyclales	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
YHH2_k127_475420_0	580332.Slit_1460	0.0	1103.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W78@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS,PAS_9,dCache_2
YHH2_k127_475420_1	580332.Slit_1459	4.335e-182	575.0	COG3287@1|root,COG3287@2|Bacteria,1R825@1224|Proteobacteria,2VPKS@28216|Betaproteobacteria,44W6E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
YHH2_k127_4776989_0	580332.Slit_2096	0.0	1378.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,44V1N@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
YHH2_k127_4776989_1	663610.JQKO01000004_gene2764	3.931e-09	61.0	COG1569@1|root,COG1569@2|Bacteria,1Q9X6@1224|Proteobacteria,2UGKA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH2_k127_4811428_3	580332.Slit_2578	3.066e-90	298.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria,44V6I@713636|Nitrosomonadales	28216|Betaproteobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
YHH2_k127_4811428_5	580332.Slit_2577	1.641e-57	202.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,2VW30@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
YHH2_k127_4811428_0	580332.Slit_2576	1.278e-241	751.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria,44V1U@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YHH2_k127_4811428_9	257310.BB2140	5.348e-24	103.0	COG3514@1|root,COG3514@2|Bacteria,1NGCR@1224|Proteobacteria,2VW6V@28216|Betaproteobacteria,3T8FV@506|Alcaligenaceae	28216|Betaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
YHH2_k127_4811428_12	1144319.PMI16_00912	1.362e-19	89.0	COG2929@1|root,COG2929@2|Bacteria,1N83Z@1224|Proteobacteria,2VVVC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_4811428_6	580332.Slit_2477	1.517e-56	208.0	COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria	1224|Proteobacteria	M	Outer membrane protein (Porin)	-	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K03285	-	-	-	-	ko00000	1.B.1	-	-	Porin_4
YHH2_k127_4811428_13	933262.AXAM01000014_gene248	3.63e-14	75.0	2CEX2@1|root,32ZNR@2|Bacteria,1N9Q4@1224|Proteobacteria,431HM@68525|delta/epsilon subdivisions,2WWIS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4811428_8	113355.CM001775_gene1185	2.591e-25	107.0	2E86T@1|root,332K1@2|Bacteria,1GFMW@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4811428_11	765911.Thivi_4135	1.288e-20	94.0	2EAHN@1|root,334KU@2|Bacteria,1NAT6@1224|Proteobacteria,1SD2M@1236|Gammaproteobacteria,1X202@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4811428_7	743299.Acife_3243	2.723e-37	146.0	2DPU2@1|root,333DK@2|Bacteria,1NCKZ@1224|Proteobacteria,1SEQE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_4811428_1	580332.Slit_2474	2.97e-118	382.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,44V79@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
YHH2_k127_4811428_2	1485544.JQKP01000004_gene453	2.081e-116	378.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria,44VW9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
YHH2_k127_4811428_4	614083.AWQR01000001_gene3031	3.037e-63	238.0	COG0515@1|root,COG0745@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K11912,ko:K12132	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	HAMP,Pkinase
YHH2_k127_4811428_14	1122164.JHWF01000017_gene503	1.147e-11	67.0	2EG8N@1|root,33A0G@2|Bacteria,1NHU3@1224|Proteobacteria,1SGMX@1236|Gammaproteobacteria,1JGA4@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4811428_10	1266925.JHVX01000018_gene1825	1.266e-20	91.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,372HU@32003|Nitrosomonadales	28216|Betaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH2_k127_4816626_0	1131553.JIBI01000009_gene1255	3.779e-156	498.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria,373E2@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
YHH2_k127_4816626_1	1485544.JQKP01000002_gene1364	3.847e-42	160.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,44VGW@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Soluble lytic murein transglycosylase L domain	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
YHH2_k127_486465_0	865937.Gilli_0818	7.293e-155	497.0	2DUAW@1|root,33PQT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_486465_1	105559.Nwat_1970	9.581e-71	245.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria,1WYN6@135613|Chromatiales	135613|Chromatiales	K	SMART cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YHH2_k127_486465_2	1191460.F959_02370	1.995e-11	68.0	COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,1RS58@1236|Gammaproteobacteria,3NP2B@468|Moraxellaceae	1236|Gammaproteobacteria	L	ISXO2-like transposase domain	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1595
YHH2_k127_4872009_3	232721.Ajs_2200	4.716e-08	54.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,2VKAK@28216|Betaproteobacteria,4AJKJ@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3
YHH2_k127_4872009_0	1265505.ATUG01000002_gene1899	1.199e-68	244.0	28MCN@1|root,2ZAQR@2|Bacteria,1N00X@1224|Proteobacteria,430JF@68525|delta/epsilon subdivisions,2WW47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4872009_1	1538295.JY96_12255	5.645e-27	123.0	COG4249@1|root,COG4249@2|Bacteria,1PGX5@1224|Proteobacteria,2VUJ9@28216|Betaproteobacteria,1KP4B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4872009_2	522306.CAP2UW1_2495	5.198e-20	90.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2VIEC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH2_k127_4873805_6	1485544.JQKP01000001_gene1216	1.701e-53	189.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria,44VAB@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
YHH2_k127_4873805_7	324925.Ppha_1715	3.599e-23	101.0	COG2929@1|root,COG2929@2|Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_4873805_11	1116472.MGMO_111c00130	6.27e-08	59.0	2ATBG@1|root,31IUH@2|Bacteria,1P76E@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4873805_2	1538295.JY96_21805	2.638e-70	247.0	2ECGA@1|root,336EK@2|Bacteria,1NG7Q@1224|Proteobacteria,2VXC5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4873805_3	1177179.A11A3_16305	1.041e-63	222.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,1RPNB@1236|Gammaproteobacteria,1XIB0@135619|Oceanospirillales	135619|Oceanospirillales	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
YHH2_k127_4873805_0	319225.Plut_0640	3.538e-121	400.0	COG3943@1|root,COG3943@2|Bacteria	2|Bacteria	-	-	Z012_01645	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
YHH2_k127_4873805_1	365044.Pnap_0378	1.044e-80	273.0	2CDN0@1|root,2ZFU0@2|Bacteria,1RC0D@1224|Proteobacteria,2VQVK@28216|Betaproteobacteria,4AH1F@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH2_k127_4873805_8	365044.Pnap_0378	1.46e-21	96.0	2CDN0@1|root,2ZFU0@2|Bacteria,1RC0D@1224|Proteobacteria,2VQVK@28216|Betaproteobacteria,4AH1F@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH2_k127_4873805_5	365044.Pnap_0377	9.795e-59	210.0	2DTWF@1|root,32UW3@2|Bacteria,1ND7X@1224|Proteobacteria,2VW14@28216|Betaproteobacteria,4AI13@80864|Comamonadaceae	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
YHH2_k127_4873805_10	489825.LYNGBM3L_74490	1.412e-09	68.0	COG2603@1|root,COG2603@2|Bacteria,1G2AY@1117|Cyanobacteria,1H91A@1150|Oscillatoriales	1117|Cyanobacteria	S	Trna 2-selenouridine synthase	ybbB	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
YHH2_k127_4873805_4	395494.Galf_1705	1.535e-59	210.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,44VMP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Rhodanese Homology Domain	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
YHH2_k127_4873805_9	1217648.F933_01396	2.563e-13	78.0	2B07J@1|root,31SIC@2|Bacteria,1QQ3H@1224|Proteobacteria,1TNWS@1236|Gammaproteobacteria,3NRGI@468|Moraxellaceae	1236|Gammaproteobacteria	S	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
YHH2_k127_4891267_1	580332.Slit_2760	1.392e-129	420.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,44V5T@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH2_k127_4891267_0	580332.Slit_2759	2.46e-209	652.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,44V93@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	pilT	-	-	ko:K02669,ko:K12203	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2,3.A.7.10.1,3.A.7.9.1	-	-	T2SSE
YHH2_k127_4891267_3	580332.Slit_2758	1.825e-110	361.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,44V25@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
YHH2_k127_4891267_2	580332.Slit_2757	3.698e-118	388.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,44V7F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
YHH2_k127_4891267_6	580332.Slit_2756	1.2e-81	276.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,2VRHV@28216|Betaproteobacteria,44VT3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
YHH2_k127_4891267_8	580332.Slit_2755	1.384e-45	167.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria,44VYI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
YHH2_k127_4891267_10	580332.Slit_2955	2.942e-31	136.0	COG5626@1|root,COG5626@2|Bacteria,1N8QB@1224|Proteobacteria,2VWJM@28216|Betaproteobacteria,44W22@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2288)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2288
YHH2_k127_4891267_5	580332.Slit_2956	1.367e-95	316.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,44VMU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YHH2_k127_4891267_7	1163617.SCD_n02933	2.899e-64	227.0	COG2863@1|root,COG2863@2|Bacteria,1RCAT@1224|Proteobacteria,2VR47@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YHH2_k127_4891267_9	987059.RBXJA2T_07413	1.563e-45	171.0	COG2863@1|root,COG2863@2|Bacteria,1PH1F@1224|Proteobacteria,2VSNV@28216|Betaproteobacteria,1KPHD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
YHH2_k127_4891267_4	580332.Slit_0265	7.018e-100	343.0	2AFYG@1|root,31628@2|Bacteria,1PWQT@1224|Proteobacteria,2WC9D@28216|Betaproteobacteria,44VMT@713636|Nitrosomonadales	580332.Slit_0265|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4896031_2	596154.Alide2_1880	9.82e-157	499.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2VH6U@28216|Betaproteobacteria,4ABAZ@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_24,rve
YHH2_k127_4896031_3	640512.BC1003_5990	2.327e-118	385.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2VHN6@28216|Betaproteobacteria,1K47T@119060|Burkholderiaceae	28216|Betaproteobacteria	L	ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
YHH2_k127_4896031_1	1165096.ARWF01000001_gene1897	4.694e-263	825.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,2KM37@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH2_k127_4896031_0	580332.Slit_2445	4.34e-306	944.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,44V8P@713636|Nitrosomonadales	28216|Betaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
YHH2_k127_4911379_4	690597.JH730963_gene2510	1.715e-17	83.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Isocitrate lyase	aceA	GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0071704	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b4015,iAF1260.b4015,iB21_1397.B21_03847,iBWG_1329.BWG_3671,iE2348C_1286.E2348C_4318,iEC042_1314.EC042_4377,iEC55989_1330.EC55989_4500,iECABU_c1320.ECABU_c45310,iECBD_1354.ECBD_4022,iECB_1328.ECB_03887,iECDH10B_1368.ECDH10B_4204,iECDH1ME8569_1439.ECDH1ME8569_3871,iECD_1391.ECD_03887,iECED1_1282.ECED1_4722,iECIAI1_1343.ECIAI1_4235,iECIAI39_1322.ECIAI39_4401,iECNA114_1301.ECNA114_4164,iECO103_1326.ECO103_4759,iECO111_1330.ECO111_4827,iECO26_1355.ECO26_5119,iECP_1309.ECP_4225,iECSE_1348.ECSE_4300,iECSF_1327.ECSF_3865,iECUMN_1333.ECUMN_4541,iECW_1372.ECW_m4374,iEKO11_1354.EKO11_4310,iETEC_1333.ETEC_4270,iEcDH1_1363.EcDH1_3982,iEcE24377_1341.EcE24377A_4557,iEcHS_1320.EcHS_A4249,iEcSMS35_1347.EcSMS35_4469,iEcolC_1368.EcolC_4015,iJO1366.b4015,iJR904.b4015,iLF82_1304.LF82_0012,iNRG857_1313.NRG857_20015,iSDY_1059.SDY_4328,iUMNK88_1353.UMNK88_4859,iWFL_1372.ECW_m4374,iY75_1357.Y75_RS20880	ICL
YHH2_k127_4911379_5	324602.Caur_3917	1.91e-05	56.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi,3753B@32061|Chloroflexia	32061|Chloroflexia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
YHH2_k127_4911379_3	1121381.JNIV01000005_gene2591	1.193e-42	170.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	NERD,zf-C4_Topoisom
YHH2_k127_4911379_0	580332.Slit_0466	1.121e-241	757.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,44VMW@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
YHH2_k127_4911379_2	580332.Slit_0464	1.241e-93	311.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2VIBH@28216|Betaproteobacteria	28216|Betaproteobacteria	U	UPF0056 inner membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
YHH2_k127_4911379_1	580332.Slit_0463	3.809e-112	363.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,2VI7P@28216|Betaproteobacteria,44VGU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	S4 RNA-binding domain	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH2_k127_492175_2	1485544.JQKP01000004_gene477	1.411e-43	169.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,44V5K@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YHH2_k127_492175_1	580332.Slit_2094	3.342e-147	470.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,44VJE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
YHH2_k127_492175_0	580332.Slit_2095	0.0	1416.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,44VDF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
YHH2_k127_492175_3	1217713.F993_02411	3.722e-37	164.0	COG1372@1|root,COG1572@1|root,COG2911@1|root,COG2931@1|root,COG3209@1|root,COG3386@1|root,COG3391@1|root,COG4254@1|root,COG1372@2|Bacteria,COG1572@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,COG4254@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,3NPVC@468|Moraxellaceae	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	rtxA	-	-	ko:K11005	-	-	-	-	ko00000,ko02000,ko02042	1.C.11	-	-	Cadherin_3,Calx-beta,DUF4347,He_PIG,HemolysinCabind,VWA,VWA_2
YHH2_k127_492175_4	44251.PDUR_25960	4.086e-19	104.0	COG1985@1|root,COG3209@1|root,COG1985@2|Bacteria,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,26RI4@186822|Paenibacillaceae	91061|Bacilli	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
YHH2_k127_492175_5	344747.PM8797T_03194	4.086e-19	104.0	COG1572@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG4625@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
YHH2_k127_4973899_2	1132855.KB913035_gene653	3.019e-251	788.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,2KP4N@206350|Nitrosomonadales	206350|Nitrosomonadales	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
YHH2_k127_4973899_6	743299.Acife_0305	1.911e-155	496.0	COG2253@1|root,COG2253@2|Bacteria,1PZRM@1224|Proteobacteria,1S18R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH2_k127_4973899_7	743299.Acife_0304	1.487e-120	390.0	COG5340@1|root,COG5340@2|Bacteria,1R1GM@1224|Proteobacteria,1S2NC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
YHH2_k127_4973899_44	1120963.KB894491_gene1107	2.048e-07	57.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4973899_3	580332.Slit_1833	1.236e-173	548.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,44WDD@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YHH2_k127_4973899_20	1123401.JHYQ01000012_gene2955	4.777e-37	144.0	COG4190@1|root,COG4190@2|Bacteria,1N98Y@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4973899_25	1485544.JQKP01000002_gene1416	9.049e-32	126.0	2E33J@1|root,32Y3P@2|Bacteria,1N9JJ@1224|Proteobacteria,2VXE1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4973899_16	396588.Tgr7_2445	1.699e-70	252.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	PRiA4_ORF3,SEC-C,UPF0149
YHH2_k127_4973899_32	715226.ABI_02260	2.236e-20	92.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_4973899_8	768671.ThimaDRAFT_1585	1.033e-117	391.0	COG2378@1|root,COG2378@2|Bacteria,1P2ZE@1224|Proteobacteria,1RYHJ@1236|Gammaproteobacteria,1WXZG@135613|Chromatiales	135613|Chromatiales	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
YHH2_k127_4973899_0	1349767.GJA_3181	0.0	1017.0	COG1203@1|root,COG1203@2|Bacteria,1MX99@1224|Proteobacteria,2VN60@28216|Betaproteobacteria	28216|Betaproteobacteria	L	CRISPR-associated helicase, Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,Helicase_C
YHH2_k127_4973899_1	1349767.GJA_3180	5.462e-258	805.0	arCOG04928@1|root,2Z880@2|Bacteria,1NBNZ@1224|Proteobacteria,2VNGI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CRISPR-associated protein Cse1 (CRISPR_cse1)	-	-	-	ko:K19123	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse1
YHH2_k127_4973899_17	1349767.GJA_3179	7.185e-63	220.0	2EMUR@1|root,33FH1@2|Bacteria,1NGE1@1224|Proteobacteria,2VY86@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CRISPR-associated protein Cse2 (CRISPR_cse2)	-	-	-	ko:K19046	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse2
YHH2_k127_4973899_5	1349767.GJA_3178	1.242e-168	536.0	COG1857@1|root,COG1857@2|Bacteria,1MVNH@1224|Proteobacteria,2VP5P@28216|Betaproteobacteria	28216|Betaproteobacteria	L	CT1975-like protein	casC	-	-	ko:K19124	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CT1975
YHH2_k127_4973899_10	1349767.GJA_3177	1.085e-107	354.0	2DBE4@1|root,2Z8QG@2|Bacteria,1RAK5@1224|Proteobacteria,2VTQH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CRISPR-associated protein (Cas_Cas5)	casD	-	-	ko:K19125	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
YHH2_k127_4973899_14	1349767.GJA_3176	2.321e-81	278.0	2DMV2@1|root,32TV5@2|Bacteria,1RCB3@1224|Proteobacteria,2VTY3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CRISPR_assoc	casE	-	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
YHH2_k127_4973899_26	1216976.AX27061_1194	5.096e-29	119.0	COG2886@1|root,COG2886@2|Bacteria,1N3WJ@1224|Proteobacteria,2VXK3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
YHH2_k127_4973899_33	1499967.BAYZ01000041_gene2400	4.988e-20	96.0	COG2405@1|root,COG2405@2|Bacteria	1499967.BAYZ01000041_gene2400|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4973899_30	631362.Thi970DRAFT_04798	5.988e-24	102.0	COG2442@1|root,COG2442@2|Bacteria,1NH1S@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YHH2_k127_4973899_21	631362.Thi970DRAFT_04797	5.301e-35	137.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
YHH2_k127_4973899_4	1458427.BAWN01000012_gene715	6.52e-169	533.0	COG1518@1|root,COG1518@2|Bacteria,1MUXH@1224|Proteobacteria,2VMT9@28216|Betaproteobacteria,4AEPI@80864|Comamonadaceae	28216|Betaproteobacteria	L	CRISPR associated protein Cas1	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
YHH2_k127_4973899_27	272568.GDI2203	1.723e-26	111.0	COG0847@1|root,COG0847@2|Bacteria,1N05B@1224|Proteobacteria,2UC74@28211|Alphaproteobacteria,2JXB5@204441|Rhodospirillales	204441|Rhodospirillales	L	CRISPR-associated protein (Cas_Cas2CT1978)	-	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas2CT1978
YHH2_k127_4973899_22	1476583.DEIPH_ctg002orf0130	1.664e-34	139.0	2A20N@1|root,30QAJ@2|Bacteria,1WNAN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4973899_50	1185876.BN8_00523	0.0006339	46.0	2DMND@1|root,32SNQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4973899_13	292415.Tbd_1808	2.848e-95	322.0	COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2VKWM@28216|Betaproteobacteria,1KTHJ@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YHH2_k127_4973899_28	1150469.RSPPHO_02475	2.071e-25	108.0	2C8HQ@1|root,333I3@2|Bacteria,1N98G@1224|Proteobacteria,2UJR7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ParG
YHH2_k127_4973899_9	1504672.669787643	5.824e-109	356.0	COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,2VM1G@28216|Betaproteobacteria,4AD1N@80864|Comamonadaceae	28216|Betaproteobacteria	D	Cobyrinic acid ac-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YHH2_k127_4973899_40	637390.AFOH01000107_gene167	3.163e-10	63.0	COG5606@1|root,COG5606@2|Bacteria,1N2FN@1224|Proteobacteria,1S9YA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	conserved small protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
YHH2_k127_4973899_34	497321.C664_05421	7.758e-20	90.0	2EK34@1|root,33DTI@2|Bacteria,1NGT0@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
YHH2_k127_4973899_31	1123401.JHYQ01000028_gene3203	8.191e-21	94.0	2E9YB@1|root,3343Z@2|Bacteria,1N8FR@1224|Proteobacteria,1SCWU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
YHH2_k127_4973899_18	420662.Mpe_B0376	8.949e-50	205.0	COG4678@1|root,COG4678@2|Bacteria,1MXCR@1224|Proteobacteria,2VVNA@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TraG-like protein, N-terminal region	-	-	-	ko:K12056	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraG_N
YHH2_k127_4973899_24	420662.Mpe_B0381	6.373e-34	151.0	28KC1@1|root,2Z9Z1@2|Bacteria,1MW96@1224|Proteobacteria,2VNCU@28216|Betaproteobacteria,1KKWT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Type-1V conjugative transfer system mating pair stabilisation	traN	-	-	ko:K12058	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraN
YHH2_k127_4973899_35	479433.Caci_4056	1.286e-15	81.0	28VTK@1|root,2ZHVA@2|Bacteria,2GSA8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4973899_48	1158338.JNLJ01000001_gene1281	3.14e-05	48.0	2DR9Y@1|root,33AUY@2|Bacteria	2|Bacteria	L	HNH endonuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3,NUMOD4
YHH2_k127_4973899_38	1005994.GTGU_02112	1.576e-14	83.0	COG1846@1|root,COG1846@2|Bacteria,1PAYS@1224|Proteobacteria,1RYGR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	mobC	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4973899_15	1159870.KB907784_gene3410	4.135e-73	256.0	2F2FN@1|root,33VD2@2|Bacteria,1QZIW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4973899_39	497321.C664_05166	8.247e-14	77.0	2DMND@1|root,32SNQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4973899_29	323259.Mhun_0506	2.779e-24	107.0	COG1569@1|root,arCOG02120@2157|Archaea	2157|Archaea	S	nucleic acid-binding protein contains PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
YHH2_k127_4973899_37	944480.ATUV01000002_gene422	2.413e-15	80.0	COG4118@1|root,COG4118@2|Bacteria,1NM68@1224|Proteobacteria,42XA0@68525|delta/epsilon subdivisions,2WT8W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_4973899_23	395494.Galf_1208	4.862e-34	134.0	COG0484@1|root,COG0484@2|Bacteria,1N2YE@1224|Proteobacteria,2VU46@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
YHH2_k127_4973899_19	883126.HMPREF9710_03685	7.161e-46	171.0	2A7IB@1|root,30WG3@2|Bacteria,1PI53@1224|Proteobacteria,2W6R3@28216|Betaproteobacteria,47752@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4973899_42	1203606.HMPREF1526_02900	5.778e-09	65.0	COG1649@1|root,COG2247@1|root,COG1649@2|Bacteria,COG2247@2|Bacteria,1V7X5@1239|Firmicutes,25G2M@186801|Clostridia	186801|Clostridia	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
YHH2_k127_5125593_2	580332.Slit_1219	1.338e-30	122.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VNB4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA1	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
YHH2_k127_5125593_0	1123377.AUIV01000012_gene721	1.687e-152	490.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria,1XAEU@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH2_k127_5125593_1	1485544.JQKP01000001_gene1061	5.3e-40	151.0	COG3271@1|root,COG3271@2|Bacteria,1R9YX@1224|Proteobacteria,2VURR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phytochelatin synthase	-	-	-	-	-	-	-	-	-	-	-	-	Phytochelatin
YHH2_k127_5153839_6	395494.Galf_0037	8.379e-36	137.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,44V03@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
YHH2_k127_5153839_0	580332.Slit_0024	0.0	1131.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,44VJG@713636|Nitrosomonadales	28216|Betaproteobacteria	P	SMART von Willebrand factor type A	cbbO2	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YHH2_k127_5153839_3	580332.Slit_0023	9.54e-156	499.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria,44UZJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ATPase associated with various cellular activities AAA_5	cbbQ2	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
YHH2_k127_5153839_2	1049564.TevJSym_aj00630	7.098e-265	820.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RYJX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the RuBisCO large chain family	cbbM	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
YHH2_k127_5153839_4	580332.Slit_0021	3.712e-154	491.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,44VAP@713636|Nitrosomonadales	28216|Betaproteobacteria	K	LysR substrate binding domain	cbbR	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
YHH2_k127_5153839_1	1304883.KI912532_gene3206	0.0	1041.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVC7@206389|Rhodocyclales	206389|Rhodocyclales	T	PAC sensor-containing diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS,PAS_9
YHH2_k127_5153839_5	1049564.TevJSym_bi00090	1.776e-107	358.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1J9WK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Di-haem cytochrome c peroxidase	yhjA	GO:0000302,GO:0003674,GO:0003824,GO:0004130,GO:0004601,GO:0005488,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009061,GO:0009636,GO:0009987,GO:0010035,GO:0015980,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017144,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0042221,GO:0042493,GO:0042542,GO:0042743,GO:0044237,GO:0045333,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C,Haem_bd
YHH2_k127_5153839_7	1121861.KB899951_gene2303	3.002e-32	139.0	COG3209@1|root,COG3209@2|Bacteria,1PHC1@1224|Proteobacteria,2V8X0@28211|Alphaproteobacteria,2JXWU@204441|Rhodospirillales	204441|Rhodospirillales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YHH2_k127_5153839_8	580332.Slit_1827	4.489e-17	87.0	COG3167@1|root,COG3167@2|Bacteria,1N0IK@1224|Proteobacteria,2VXJE@28216|Betaproteobacteria,44WKP@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	carbon utilization	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_519444_6	765911.Thivi_1063	4.153e-71	257.0	COG2995@1|root,COG2995@2|Bacteria,1R864@1224|Proteobacteria,1T67W@1236|Gammaproteobacteria,1WXD3@135613|Chromatiales	135613|Chromatiales	S	Paraquat-inducible protein A	-	-	-	-	-	-	-	-	-	-	-	-	PqiA
YHH2_k127_519444_17	1165841.SULAR_02403	1.388e-10	64.0	2DFKD@1|root,2ZS7E@2|Bacteria,1P5EA@1224|Proteobacteria	1224|Proteobacteria	S	Pfam:DUF1049	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
YHH2_k127_519444_7	1163617.SCD_n00730	1.277e-45	168.0	2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,2VWT7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_519444_3	1349767.GJA_4518	4.176e-113	374.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,475P1@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YHH2_k127_519444_13	118173.KB235914_gene3028	6.474e-20	93.0	28IYQ@1|root,2Z8WB@2|Bacteria	2|Bacteria	S	Type II restriction endonuclease EcoO109I	-	-	-	-	-	-	-	-	-	-	-	-	RE_EcoO109I
YHH2_k127_519444_14	228405.HNE_2543	5.651e-18	87.0	COG1813@1|root,COG1813@2|Bacteria,1NANQ@1224|Proteobacteria,2TXAN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH2_k127_519444_19	36874.HQ34_01050	2.073e-05	48.0	COG0270@1|root,COG0789@1|root,COG0270@2|Bacteria,COG0789@2|Bacteria,4NG9A@976|Bacteroidetes,2FTMC@200643|Bacteroidia	976|Bacteroidetes	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_17,MerR,MerR_1
YHH2_k127_519444_2	1132855.KB913035_gene1363	4.917e-185	610.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE1,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
YHH2_k127_519444_18	1502852.FG94_04728	5.33e-08	61.0	COG3637@1|root,COG3637@2|Bacteria,1PWWU@1224|Proteobacteria,2WCF6@28216|Betaproteobacteria,477GQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl
YHH2_k127_519444_16	1044.EH31_00305	3.233e-14	84.0	COG4719@1|root,COG4719@2|Bacteria,1RARY@1224|Proteobacteria,2U6NU@28211|Alphaproteobacteria,2K9JU@204457|Sphingomonadales	204457|Sphingomonadales	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_519444_10	96561.Dole_3252	5.166e-33	135.0	COG4719@1|root,COG4719@2|Bacteria,1N09K@1224|Proteobacteria,42UTG@68525|delta/epsilon subdivisions,2WQR7@28221|Deltaproteobacteria,2MP1P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH2_k127_519444_9	1504672.669784445	2.168e-36	152.0	COG4719@1|root,COG4719@2|Bacteria,1R87U@1224|Proteobacteria	1224|Proteobacteria	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH2_k127_519444_0	1232410.KI421421_gene3529	0.0	1225.0	COG2067@1|root,COG2885@1|root,COG2067@2|Bacteria,COG2885@2|Bacteria,1MY5K@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH2_k127_519444_15	1121116.KB894771_gene1413	4.005e-16	91.0	COG2885@1|root,COG2913@1|root,COG2885@2|Bacteria,COG2913@2|Bacteria,1N6EM@1224|Proteobacteria,2WEXT@28216|Betaproteobacteria,4ADTI@80864|Comamonadaceae	28216|Betaproteobacteria	JM	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,SmpA_OmlA
YHH2_k127_519444_12	580332.Slit_0182	7.752e-21	101.0	COG3637@1|root,COG3637@2|Bacteria,1NIE3@1224|Proteobacteria,2VXMU@28216|Betaproteobacteria,44WMS@713636|Nitrosomonadales	28216|Betaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA_membrane
YHH2_k127_519444_5	426114.THI_2295	2.103e-71	242.0	COG1487@1|root,COG1487@2|Bacteria,1RJDP@1224|Proteobacteria,2WGAS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH2_k127_519444_1	1026882.MAMP_01998	2.805e-228	726.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,45ZN9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
YHH2_k127_5208239_1	580332.Slit_2026	2.916e-107	353.0	COG0063@1|root,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,44VJ1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
YHH2_k127_5208239_3	580332.Slit_2027	3.025e-65	228.0	2BWTE@1|root,32YDB@2|Bacteria,1N0HE@1224|Proteobacteria,2VYW4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2937
YHH2_k127_5208239_0	261292.Nit79A3_1349	3.832e-131	422.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria,372CE@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Spermine/spermidine synthase domain	speE1	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
YHH2_k127_5208239_9	580332.Slit_2029	6.359e-14	76.0	2ENVQ@1|root,33GGS@2|Bacteria,1NGVT@1224|Proteobacteria,2VY6X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
YHH2_k127_5208239_4	580332.Slit_2030	1.576e-45	167.0	COG1993@1|root,COG1993@2|Bacteria,1RH30@1224|Proteobacteria,2WFX5@28216|Betaproteobacteria,44W30@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1993	-	-	-	-	-	-	-	-	-	-	-	-	DUF190
YHH2_k127_5208239_2	580332.Slit_2031	8.17e-71	242.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2VUBZ@28216|Betaproteobacteria,44VTA@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
YHH2_k127_5208239_11	519989.ECTPHS_00804	6.543e-08	57.0	2EFWZ@1|root,339P8@2|Bacteria,1Q1AB@1224|Proteobacteria,1SVKF@1236|Gammaproteobacteria,1X20G@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5208239_5	765912.Thimo_2722	3.306e-34	136.0	COG1569@1|root,COG1569@2|Bacteria,1NJ68@1224|Proteobacteria,1SAF3@1236|Gammaproteobacteria,1X17S@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH2_k127_5208239_10	879212.DespoDRAFT_03729	9.36e-14	75.0	2DTN3@1|root,33M10@2|Bacteria,1NPRB@1224|Proteobacteria	1224|Proteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
YHH2_k127_5208239_6	378806.STAUR_0345	5.768e-24	120.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria,2YX17@29|Myxococcales	28221|Deltaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,Kelch_1,Kelch_4
YHH2_k127_5208239_12	1144319.PMI16_00169	1.6e-06	63.0	COG3468@1|root,COG3468@2|Bacteria,1QUZ3@1224|Proteobacteria,2WGMH@28216|Betaproteobacteria,4731U@75682|Oxalobacteraceae	28216|Betaproteobacteria	MU	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,He_PIG
YHH2_k127_5208239_7	477641.MODMU_0965	1.077e-21	113.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4ETCD@85013|Frankiales	201174|Actinobacteria	S	Laminin G domain	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
YHH2_k127_5208239_8	1182590.BN5_02109	2.852e-14	78.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria	1224|Proteobacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
YHH2_k127_5271151_4	1049564.TevJSym_bo00190	3.736e-85	293.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,1RQ9A@1236|Gammaproteobacteria,1J616@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT,EB_dh
YHH2_k127_5271151_5	1123519.PSJM300_03235	4.604e-59	211.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,1RQ9A@1236|Gammaproteobacteria,1Z1N9@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT,EB_dh
YHH2_k127_5271151_7	1304883.KI912532_gene1294	3.074e-34	134.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2VU95@28216|Betaproteobacteria,2KX4B@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulphur oxidation protein SoxZ	soxZ	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
YHH2_k127_5271151_6	159087.Daro_3132	2.9e-34	138.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria,2KWNG@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulfur oxidation protein SoxY	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
YHH2_k127_5271151_0	1163617.SCD_n02021	0.0	1089.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
YHH2_k127_5271151_2	1049564.TevJSym_ab00440	1.931e-270	846.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1J8SM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Citrate transporter	sac1	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
YHH2_k127_5271151_1	1163617.SCD_n02017	2.93e-307	949.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
YHH2_k127_5271151_3	580332.Slit_1709	5.947e-173	546.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria,44WEC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
YHH2_k127_5290242_14	580332.Slit_0887	2.183e-32	127.0	2E4UR@1|root,32ZP4@2|Bacteria,1N83W@1224|Proteobacteria,2VYMU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5290242_7	580332.Slit_0886	7.264e-121	391.0	COG1433@1|root,COG1433@2|Bacteria,1PW6J@1224|Proteobacteria,2WFJ3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Pfam Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DIMCO_N,Nitro_FeMo-Co
YHH2_k127_5290242_15	580332.Slit_0885	6.8e-31	122.0	COG1145@1|root,COG1145@2|Bacteria,1N859@1224|Proteobacteria,2VXWM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
YHH2_k127_5290242_13	580332.Slit_0884	6.351e-36	139.0	COG5554@1|root,COG5554@2|Bacteria	2|Bacteria	Q	nitrogen fixation	nifT	-	-	ko:K02593	-	-	-	-	ko00000	-	-	-	NifT
YHH2_k127_5290242_0	580332.Slit_0883	8.615e-318	977.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,2VIUM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	nifK	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
YHH2_k127_5290242_1	580332.Slit_0882	5.744e-307	943.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,2VHMG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrogenase molybdenum-iron protein alpha chain	nifD	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
YHH2_k127_5290242_3	580332.Slit_0881	5.034e-180	565.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2VIK4@28216|Betaproteobacteria	28216|Betaproteobacteria	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
YHH2_k127_5290242_25	580332.Slit_0880	0.0005446	45.0	28IJT@1|root,2Z8KN@2|Bacteria,1R6VB@1224|Proteobacteria,2VJQS@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM Dinitrogenase reductase ADP-ribosyltransferase	draT	-	2.4.2.37	ko:K05951	-	-	-	-	ko00000,ko01000	-	-	-	DRAT
YHH2_k127_5290242_5	580332.Slit_0880	3.548e-159	507.0	28IJT@1|root,2Z8KN@2|Bacteria,1R6VB@1224|Proteobacteria,2VJQS@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM Dinitrogenase reductase ADP-ribosyltransferase	draT	-	2.4.2.37	ko:K05951	-	-	-	-	ko00000,ko01000	-	-	-	DRAT
YHH2_k127_5290242_19	498211.CJA_0814	2.701e-20	102.0	2DY3P@1|root,347Z2@2|Bacteria,1NZVK@1224|Proteobacteria,1SR8X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5290242_11	1121948.AUAC01000002_gene1108	1.742e-43	162.0	COG2337@1|root,COG2337@2|Bacteria,1MZJ8@1224|Proteobacteria,2U9QV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH2_k127_5290242_17	1288494.EBAPG3_27250	1.151e-25	108.0	COG2336@1|root,COG2336@2|Bacteria,1N9Z6@1224|Proteobacteria,2VWF3@28216|Betaproteobacteria	28216|Betaproteobacteria	T	SpoVT / AbrB like domain	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_5290242_8	1288494.EBAPG3_22190	1.974e-120	391.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,374MX@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH2_k127_5290242_10	637390.AFOH01000008_gene621	2.507e-59	210.0	COG1487@1|root,COG1487@2|Bacteria,1RJ2J@1224|Proteobacteria,1S81V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	nucleic acid-binding protein, contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_5290242_12	637390.AFOH01000008_gene620	2.175e-37	141.0	COG2002@1|root,COG2002@2|Bacteria,1NA8P@1224|Proteobacteria,1T0GE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	prlF antitoxin for toxin YhaV_toxin	-	-	-	-	-	-	-	-	-	-	-	-	PrlF_antitoxin
YHH2_k127_5290242_18	938288.HG326228_gene197	5.627e-21	96.0	COG3617@1|root,COG3617@2|Bacteria,1TS1A@1239|Firmicutes,2486G@186801|Clostridia,26A02@186813|unclassified Clostridiales	186801|Clostridia	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
YHH2_k127_5290242_9	1408444.JHYC01000011_gene1002	2.774e-66	231.0	COG3617@1|root,COG3617@2|Bacteria,1QX1C@1224|Proteobacteria	1224|Proteobacteria	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
YHH2_k127_5290242_23	1122212.AULO01000012_gene1134	7.881e-12	80.0	COG0582@1|root,COG0582@2|Bacteria,1QYZQ@1224|Proteobacteria,1RSEW@1236|Gammaproteobacteria,1XMD3@135619|Oceanospirillales	135619|Oceanospirillales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YHH2_k127_5290242_21	1182590.BN5_00896	1.025e-12	69.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,1YEEH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
YHH2_k127_5290242_2	1123487.KB892865_gene1413	4.892e-186	586.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2VIY1@28216|Betaproteobacteria,2KXBH@206389|Rhodocyclales	206389|Rhodocyclales	S	Fic/DOC family N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
YHH2_k127_5290242_20	743299.Acife_0527	5.485e-16	78.0	COG3587@1|root,COG3587@2|Bacteria,1MVQ0@1224|Proteobacteria,1RPN2@1236|Gammaproteobacteria,2NE34@225057|Acidithiobacillales	1236|Gammaproteobacteria	L	PFAM Restriction endonuclease, type I, R subunit Type III, Res subunit	res	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
YHH2_k127_5290242_24	1055815.AYYA01000036_gene4	5.312e-06	50.0	COG2865@1|root,COG2865@2|Bacteria,1MXG1@1224|Proteobacteria,1S1HY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
YHH2_k127_5290242_26	224911.27350827	0.0006648	44.0	2F0SV@1|root,33TUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5290242_4	580332.Slit_0321	3.53e-174	552.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,44V15@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Polyprenyl synthetase	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH2_k127_5290242_6	580332.Slit_0320	4.742e-152	484.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VIPI@28216|Betaproteobacteria,44WDF@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	proP	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH2_k127_5322455_3	1182590.BN5_03571	3.153e-05	47.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,1RQHU@1236|Gammaproteobacteria,1YF58@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
YHH2_k127_5322455_1	580332.Slit_0331	3.945e-185	587.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,44VNZ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	TIGRFAM phosphate regulon sensor kinase PhoR	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
YHH2_k127_5322455_2	580332.Slit_0330	4.602e-132	424.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,44V17@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Two component transcriptional regulator PhoB, winged helix family	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_5322455_0	1123517.JOMR01000001_gene934	1.433e-206	653.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1SYH6@1236|Gammaproteobacteria,463T0@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH2_k127_5332750_11	522306.CAP2UW1_4222	1.733e-21	104.0	2ED2U@1|root,336ZR@2|Bacteria,1NBHE@1224|Proteobacteria,2W0JM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5332750_12	269799.Gmet_1339	4.624e-08	58.0	COG2002@1|root,COG2002@2|Bacteria,1N3BE@1224|Proteobacteria	1224|Proteobacteria	K	AbrB family	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
YHH2_k127_5332750_9	290317.Cpha266_0264	6.963e-45	164.0	29X02@1|root,30INB@2|Bacteria,1FFD4@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
YHH2_k127_5332750_10	290317.Cpha266_0265	1.798e-28	117.0	2BWX9@1|root,330PJ@2|Bacteria,1FFHH@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH2_k127_5332750_8	572477.Alvin_3261	1.846e-49	180.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,1S4KB@1236|Gammaproteobacteria,1WZJ9@135613|Chromatiales	135613|Chromatiales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
YHH2_k127_5332750_0	580332.Slit_2378	3.473e-241	751.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,44VHH@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM peptidase U62 modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YHH2_k127_5332750_5	580332.Slit_2379	7.848e-90	298.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,44VT9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF615)	yjgA	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
YHH2_k127_5332750_6	1485544.JQKP01000004_gene494	5.267e-87	292.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,44VRU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
YHH2_k127_5332750_1	580332.Slit_2383	1.116e-192	613.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5332750_3	580332.Slit_2384	1.632e-116	386.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,44VGV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
YHH2_k127_5332750_2	580332.Slit_2385	9.096e-135	431.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,44V40@713636|Nitrosomonadales	28216|Betaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
YHH2_k127_5332750_4	580332.Slit_2386	3.453e-110	364.0	2B3KG@1|root,31W9T@2|Bacteria,1PWY8@1224|Proteobacteria,2WCG4@28216|Betaproteobacteria,44W0P@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5332750_7	580332.Slit_2387	2.399e-69	236.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,44VPF@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YHH2_k127_5334378_1	1499967.BAYZ01000080_gene902	1.622e-112	368.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HNH
YHH2_k127_5334378_0	870187.Thini_1996	3.047e-124	406.0	COG0338@1|root,COG0338@2|Bacteria,1QS19@1224|Proteobacteria,1RVBM@1236|Gammaproteobacteria,462K4@72273|Thiotrichales	72273|Thiotrichales	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MethyltransfD12
YHH2_k127_5334612_2	580332.Slit_2091	1.121e-161	514.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,44VNX@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
YHH2_k127_5334612_0	580332.Slit_2090	0.0	1641.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,44V7X@713636|Nitrosomonadales	28216|Betaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YHH2_k127_5334612_3	580332.Slit_2089	1.607e-77	263.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,44VXG@713636|Nitrosomonadales	28216|Betaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
YHH2_k127_5334612_1	580332.Slit_2088	1.71e-163	520.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,44V90@713636|Nitrosomonadales	28216|Betaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
YHH2_k127_5334703_0	640081.Dsui_3035	6.086e-108	362.0	COG2199@1|root,COG3706@2|Bacteria,1N7HG@1224|Proteobacteria,2VPE2@28216|Betaproteobacteria,2KUP8@206389|Rhodocyclales	206389|Rhodocyclales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
YHH2_k127_5367038_4	156889.Mmc1_1112	2.04e-116	385.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate Guanylate cyclase	cyaD1	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
YHH2_k127_5367038_5	1116472.MGMO_105c00230	1.023e-115	382.0	COG2199@1|root,COG3706@2|Bacteria,1REIE@1224|Proteobacteria,1SPFU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	cyclic nucleotide-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,cNMP_binding
YHH2_k127_5367038_6	580332.Slit_0669	2.1e-104	343.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria,44VBW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
YHH2_k127_5367038_7	580332.Slit_0670	1.044e-80	273.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,44VQD@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
YHH2_k127_5367038_2	580332.Slit_0671	6.241e-178	564.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,44V3Q@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
YHH2_k127_5367038_3	580332.Slit_0672	8.958e-120	394.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,44V9I@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
YHH2_k127_5367038_0	580332.Slit_0673	0.0	1095.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,44V1S@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
YHH2_k127_5367038_1	580332.Slit_0675	1.07e-273	849.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,44VP0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
YHH2_k127_5387381_3	455436.DS989810_gene147	4.593e-15	76.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,4647V@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
YHH2_k127_5387381_1	1123367.C666_14650	5.67e-193	609.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2VNF8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH2_k127_5387381_0	261292.Nit79A3_2136	0.0	1551.0	COG5635@1|root,COG5635@2|Bacteria,1NC67@1224|Proteobacteria	1224|Proteobacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5387381_2	580332.Slit_2308	1.382e-178	571.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,2VX93@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
YHH2_k127_5387715_0	580332.Slit_2154	2.225e-256	798.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria,44W4Y@713636|Nitrosomonadales	28216|Betaproteobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
YHH2_k127_5387715_2	580332.Slit_2153	2.737e-51	186.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,44W1F@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YHH2_k127_5387715_4	1485544.JQKP01000017_gene638	4.173e-19	92.0	COG2703@1|root,COG2703@2|Bacteria,1N9YV@1224|Proteobacteria	1224|Proteobacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
YHH2_k127_5387715_1	1121015.N789_09700	2.22e-85	295.0	COG5397@1|root,COG5397@2|Bacteria,1PJM3@1224|Proteobacteria	1224|Proteobacteria	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_8
YHH2_k127_5387715_8	1485544.JQKP01000017_gene638	8.012e-06	50.0	COG2703@1|root,COG2703@2|Bacteria,1N9YV@1224|Proteobacteria	1224|Proteobacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
YHH2_k127_5387715_5	580332.Slit_0894	3.769e-18	98.0	COG4235@1|root,COG4461@1|root,COG4235@2|Bacteria,COG4461@2|Bacteria,1NGDW@1224|Proteobacteria,2VYDV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	LprI
YHH2_k127_5387715_7	706587.Desti_5617	7.233e-10	72.0	COG0666@1|root,COG0666@2|Bacteria,1N0BQ@1224|Proteobacteria,42VU1@68525|delta/epsilon subdivisions,2WSF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4
YHH2_k127_5387715_3	395494.Galf_0854	4.35e-48	175.0	COG4190@1|root,COG4190@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
YHH2_k127_5387715_9	658187.LDG_6897	0.0003039	45.0	2B35H@1|root,31VTD@2|Bacteria,1RJF7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5423261_0	580332.Slit_0184	2.079e-232	722.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKJI@28216|Betaproteobacteria,44VNF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH2_k127_5423261_1	580332.Slit_0183	1.97e-207	655.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,44VJM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
YHH2_k127_5423705_2	580332.Slit_2633	1.359e-217	685.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,44VDT@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_5423705_1	580332.Slit_2634	9.881e-224	705.0	COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,2WHEY@28216|Betaproteobacteria,44V0X@713636|Nitrosomonadales	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
YHH2_k127_5423705_11	1485544.JQKP01000001_gene1024	1.425e-17	86.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,44W3C@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
YHH2_k127_5423705_5	580332.Slit_0877	1.242e-163	524.0	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,2VM9W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
YHH2_k127_5423705_9	580332.Slit_0876	4.211e-52	187.0	COG2703@1|root,COG2703@2|Bacteria,1MZJ3@1224|Proteobacteria,2VVGT@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5423705_4	1523503.JPMY01000005_gene1936	2.415e-165	535.0	COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaB	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600	-	ko:K03314	-	-	-	-	ko00000,ko02000	2.A.34.1	-	iECP_1309.ECP_1229,iLF82_1304.LF82_1485,iNRG857_1313.NRG857_06055,iUTI89_1310.UTI89_C1372	NhaB
YHH2_k127_5423705_10	580332.Slit_0864	3.671e-41	156.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VU9E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
YHH2_k127_5423705_7	580332.Slit_0863	2.538e-99	328.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2VNWT@28216|Betaproteobacteria,44UYJ@713636|Nitrosomonadales	1224|Proteobacteria	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
YHH2_k127_5423705_6	580332.Slit_0862	4.778e-100	329.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,2VS39@28216|Betaproteobacteria,44VR1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
YHH2_k127_5423705_3	580332.Slit_0861	7.013e-205	639.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,2VKUY@28216|Betaproteobacteria,44WPH@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
YHH2_k127_5423705_0	580332.Slit_0860	2.962e-267	828.0	COG4656@1|root,COG4656@2|Bacteria,1PJVF@1224|Proteobacteria,2VM4P@28216|Betaproteobacteria,44VIW@713636|Nitrosomonadales	2|Bacteria	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,Fer4_7,Fer4_8,RnfC_N,SLBB
YHH2_k127_5423705_8	580332.Slit_0859	5.724e-57	199.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,44VN8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
YHH2_k127_5478714_2	357804.Ping_0949	2.258e-230	756.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QIXR@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
YHH2_k127_5478714_3	580332.Slit_1659	4.493e-150	479.0	COG3221@1|root,COG3221@2|Bacteria,1MX7I@1224|Proteobacteria,2VP4Q@28216|Betaproteobacteria,44VB1@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
YHH2_k127_5478714_1	580332.Slit_1658	5.708e-248	777.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHIC@28216|Betaproteobacteria,44WDC@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,sCache_3_2
YHH2_k127_5478714_0	1485544.JQKP01000010_gene837	0.0	1085.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,44VEJ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
YHH2_k127_5550265_0	580332.Slit_1704	1.09e-88	295.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,44VQC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
YHH2_k127_5550265_2	580332.Slit_1703	9.994e-66	227.0	COG3439@1|root,COG3439@2|Bacteria,1RHPD@1224|Proteobacteria,2VV5X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
YHH2_k127_5550265_1	555778.Hneap_0174	1.244e-83	296.0	COG3746@1|root,COG3746@2|Bacteria,1R8Q0@1224|Proteobacteria,1S1UE@1236|Gammaproteobacteria,1WYF2@135613|Chromatiales	135613|Chromatiales	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
YHH2_k127_5550265_3	555778.Hneap_0173	4.911e-22	102.0	COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,1S983@1236|Gammaproteobacteria,1X0YN@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5584320_0	1121035.AUCH01000022_gene3191	0.0	1049.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2VK7T@28216|Betaproteobacteria,2KUKS@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
YHH2_k127_5584320_5	1123487.KB892857_gene2506	1.435e-63	226.0	28IT1@1|root,2Z8S1@2|Bacteria,1PUT6@1224|Proteobacteria,2VTT1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
YHH2_k127_5584320_3	760117.JN27_15590	9.404e-92	308.0	COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,2VIYU@28216|Betaproteobacteria,474EB@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
YHH2_k127_5584320_2	580332.Slit_0461	1.834e-159	505.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,44VD2@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Transporter associated domain	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
YHH2_k127_5584320_4	580332.Slit_0460	5.332e-70	239.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,44VUQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
YHH2_k127_5584320_1	580332.Slit_0458	3.807e-252	782.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,44V1C@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YHH2_k127_5584320_7	153948.NAL212_1965	6.679e-18	89.0	2DR34@1|root,339YW@2|Bacteria,1NMQA@1224|Proteobacteria,2VY5F@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_39
YHH2_k127_5584320_6	153948.NAL212_2543	5.627e-20	91.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	ko:K07733	-	-	-	-	ko00000,ko03000	-	-	-	Phage_AlpA
YHH2_k127_5584320_8	395494.Galf_2038	1.929e-12	73.0	2FGGA@1|root,348C9@2|Bacteria,1P35Z@1224|Proteobacteria,2W4VB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5602036_1	395494.Galf_1809	6.84e-147	466.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,44VJZ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH2_k127_5602036_4	713587.THITH_08560	2.448e-33	132.0	2E8UR@1|root,33355@2|Bacteria,1MYPY@1224|Proteobacteria,1S6SI@1236|Gammaproteobacteria,1WYQ0@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5602036_0	1121939.L861_22710	9.378e-227	712.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1XI2N@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH2_k127_5602036_5	1163617.SCD_n00527	9.098e-18	91.0	2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,2W5RM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5602036_3	292415.Tbd_1574	4.55e-49	179.0	2D5Q1@1|root,32TJK@2|Bacteria,1N688@1224|Proteobacteria,2W3MN@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5602036_2	338969.Rfer_2229	7.08e-84	282.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2VJM3@28216|Betaproteobacteria,4AC1Z@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Methyltransferase type 11	ubiE_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YHH2_k127_5631683_0	580332.Slit_2864	0.0	1130.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,44WA6@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
YHH2_k127_5657898_0	580332.Slit_2025	0.0	2309.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,44VBS@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
YHH2_k127_5657898_1	580332.Slit_2026	2.944e-16	79.0	COG0063@1|root,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,44VJ1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
YHH2_k127_566395_1	580332.Slit_1881	0.0	1121.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,44VG6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DEAD DEAH box helicase domain protein	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
YHH2_k127_566395_0	522306.CAP2UW1_0364	0.0	2190.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VK5C@28216|Betaproteobacteria	28216|Betaproteobacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,DEAD,Helicase_C,UvrD-helicase,UvrD_C
YHH2_k127_566395_6	1415779.JOMH01000001_gene227	3.955e-59	209.0	COG0454@1|root,COG0454@2|Bacteria,1QUS5@1224|Proteobacteria,1T300@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
YHH2_k127_566395_8	99598.Cal7507_4651	1.118e-20	94.0	COG4453@1|root,COG4453@2|Bacteria,1GB3G@1117|Cyanobacteria,1HPD0@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
YHH2_k127_566395_3	580332.Slit_1882	5.133e-310	955.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2VKCX@28216|Betaproteobacteria,44V29@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YHH2_k127_566395_7	1485544.JQKP01000003_gene263	4.168e-31	126.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,44W01@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
YHH2_k127_566395_4	580332.Slit_1884	7.464e-248	768.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,44VKW@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
YHH2_k127_566395_5	580332.Slit_1885	7.342e-171	540.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,44VM7@713636|Nitrosomonadales	28216|Betaproteobacteria	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
YHH2_k127_566395_2	580332.Slit_1886	0.0	1048.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,44VDY@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
YHH2_k127_572306_1	396588.Tgr7_0273	4.25e-15	80.0	COG1266@1|root,COG1266@2|Bacteria,1NHPM@1224|Proteobacteria,1SGEZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YHH2_k127_572306_0	395495.Lcho_0341	3.126e-79	293.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VIXC@28216|Betaproteobacteria,1KJFV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the peptidase S8 family	mprA	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
YHH2_k127_5728910_1	580332.Slit_2290	1.604e-161	513.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,44VGM@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YHH2_k127_5728910_8	580332.Slit_2289	5.807e-44	168.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,44W4F@713636|Nitrosomonadales	28216|Betaproteobacteria	M	NlpB/DapX lipoprotein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
YHH2_k127_5728910_2	580332.Slit_2288	8.713e-108	354.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria,44V64@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
YHH2_k127_5728910_4	580332.Slit_2287	8.366e-79	270.0	2E3EJ@1|root,32YDJ@2|Bacteria,1N8MS@1224|Proteobacteria,2VW4J@28216|Betaproteobacteria,44WH3@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5728910_0	580332.Slit_2286	1.179e-179	580.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,44V9M@713636|Nitrosomonadales	28216|Betaproteobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	ycfD	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
YHH2_k127_5728910_5	580332.Slit_2285	1.711e-76	258.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VRCR@28216|Betaproteobacteria,44WEK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Bacterial protein of unknown function (DUF899)	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YHH2_k127_5728910_3	580332.Slit_2284	5.144e-93	306.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2VQA2@28216|Betaproteobacteria,44VUC@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
YHH2_k127_5728910_7	580332.Slit_2282	1.578e-60	211.0	2E4TM@1|root,32ZMZ@2|Bacteria,1NAT5@1224|Proteobacteria,2VXD9@28216|Betaproteobacteria,44WMC@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5728910_6	580332.Slit_1006	3.354e-67	229.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,44UZW@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
YHH2_k127_5784911_0	1485544.JQKP01000001_gene1165	0.0	1089.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44VNU@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD4	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YHH2_k127_5798237_0	580332.Slit_0181	1.787e-319	979.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,44VAJ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
YHH2_k127_5798635_4	580332.Slit_2423	9.032e-64	223.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,44W7Y@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
YHH2_k127_5798635_0	1288494.EBAPG3_10000	6.438e-291	912.0	COG0464@1|root,COG0464@2|Bacteria,1QYHP@1224|Proteobacteria,2VZ54@28216|Betaproteobacteria	28216|Betaproteobacteria	O	growth	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5798635_6	580332.Slit_2422	1.396e-40	151.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,2VVZH@28216|Betaproteobacteria,44WJT@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
YHH2_k127_5798635_1	580332.Slit_2421	6.901e-232	720.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,2VHKM@28216|Betaproteobacteria,44W7R@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
YHH2_k127_5798635_5	243233.MCA0550	3.353e-46	171.0	COG2189@1|root,COG2852@1|root,COG2189@2|Bacteria,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SA4A@1236|Gammaproteobacteria,1XFUA@135618|Methylococcales	135618|Methylococcales	L	Protein of unknown function (DUF559)	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF559
YHH2_k127_5798635_2	580332.Slit_2419	2.121e-201	629.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2VH3K@28216|Betaproteobacteria,44W8A@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM AIR synthase related protein domain protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
YHH2_k127_5798635_3	640081.Dsui_1154	1.014e-189	606.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KUEY@206389|Rhodocyclales	206389|Rhodocyclales	T	Bacterial regulatory protein, Fis family	hoxA	-	-	ko:K19641	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_5818258_2	194439.CT0720	9.894e-45	170.0	COG3404@1|root,COG3404@2|Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
YHH2_k127_5818258_1	517417.Cpar_0686	5.162e-86	297.0	COG0190@1|root,COG0190@2|Bacteria,1FE78@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
YHH2_k127_5818258_0	580332.Slit_0442	1.541e-300	932.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,44VNP@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
YHH2_k127_5828651_0	580332.Slit_2617	0.0	1841.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,44VJ0@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH2_k127_5828651_4	580332.Slit_2618	7.528e-168	532.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria,44VMF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
YHH2_k127_5828651_11	580332.Slit_2619	1.867e-50	181.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,44VY1@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	bigR	-	-	-	-	-	-	-	-	-	-	-	HTH_5
YHH2_k127_5828651_1	580332.Slit_2620	7.494e-294	906.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,44V6E@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
YHH2_k127_5828651_5	580332.Slit_2621	6.278e-163	523.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,44VHE@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Peptidase family M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH2_k127_5828651_2	580332.Slit_2622	2.793e-237	740.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,44VD5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
YHH2_k127_5828651_10	580332.Slit_2623	1.252e-54	194.0	2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,2VT9E@28216|Betaproteobacteria,44W2C@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5828651_14	522306.CAP2UW1_1037	2.186e-12	66.0	COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,2VJQH@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH2_k127_5828651_13	522306.CAP2UW1_1037	1.533e-16	84.0	COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,2VJQH@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH2_k127_5828651_8	580332.Slit_0274	4.048e-110	364.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,44V5F@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	NAD(P)H-binding	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
YHH2_k127_5828651_3	580332.Slit_0273	1.188e-173	550.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,44V1J@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Oxidoreductase FAD-binding domain protein	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
YHH2_k127_5828651_6	580332.Slit_0270	5.538e-150	485.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria,44VZN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	HemY protein N-terminus	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_12
YHH2_k127_5828651_7	580332.Slit_0269	9.72e-125	409.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,2VMG1@28216|Betaproteobacteria,44V4N@713636|Nitrosomonadales	28216|Betaproteobacteria	H	HemX, putative uroporphyrinogen-III C-methyltransferase	hemX	-	2.1.1.107,4.2.1.75	ko:K02496,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,HemX
YHH2_k127_5828651_9	580332.Slit_0268	3.382e-84	288.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,2VRU9@28216|Betaproteobacteria,44VS4@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
YHH2_k127_5828651_12	580332.Slit_0267	2.266e-30	120.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,44V8C@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
YHH2_k127_5872742_3	1500897.JQNA01000002_gene798	6.051e-67	236.0	COG0642@1|root,COG2205@2|Bacteria,1NFHM@1224|Proteobacteria,2WF79@28216|Betaproteobacteria,1KHZA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YHH2_k127_5872742_2	395494.Galf_1448	2.678e-75	260.0	COG2771@1|root,COG2771@2|Bacteria,1N6UR@1224|Proteobacteria,2WGVQ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K18304	ko02024,ko02025,map02024,map02025	M00644,M00769	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Autoind_bind,GerE
YHH2_k127_5872742_1	1453500.AT05_02020	9.024e-79	281.0	2C135@1|root,2Z9TE@2|Bacteria,4NKEZ@976|Bacteroidetes,1I0HM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5872742_4	1122212.AULO01000007_gene2391	3.93e-57	207.0	COG3271@1|root,COG3271@2|Bacteria,1RECA@1224|Proteobacteria,1S5HX@1236|Gammaproteobacteria,1XMG4@135619|Oceanospirillales	135619|Oceanospirillales	S	Peptidase C39 family	-	-	-	ko:K06992	-	-	-	-	ko00000	-	-	-	Peptidase_C39
YHH2_k127_5872742_0	580332.Slit_2781	0.0	1216.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,44V5N@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH2_k127_5872742_5	580332.Slit_2776	4.945e-37	141.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,2VVRU@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YHH2_k127_5910248_0	580332.Slit_0445	0.0	1867.0	COG1643@1|root,COG2852@1|root,COG1643@2|Bacteria,COG2852@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,44VDV@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
YHH2_k127_5910248_7	580332.Slit_0404	4.398e-116	374.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,44VFE@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
YHH2_k127_5910248_2	765911.Thivi_2874	0.0	1076.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,1WVVZ@135613|Chromatiales	135613|Chromatiales	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
YHH2_k127_5910248_4	1333856.L686_08485	9.561e-180	569.0	COG3177@1|root,COG3177@2|Bacteria,1PMMQ@1224|Proteobacteria,1T9TM@1236|Gammaproteobacteria,1Z3NS@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH2_k127_5910248_10	13035.Dacsa_2102	4.771e-94	323.0	COG0732@1|root,COG0732@2|Bacteria,1G78P@1117|Cyanobacteria	1117|Cyanobacteria	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
YHH2_k127_5910248_6	870187.Thini_2225	1.026e-138	450.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RRCR@1236|Gammaproteobacteria,4611I@72273|Thiotrichales	72273|Thiotrichales	S	Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
YHH2_k127_5910248_1	589865.DaAHT2_2025	0.0	1540.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria,2MJD5@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
YHH2_k127_5910248_9	589865.DaAHT2_2026	1.665e-103	341.0	COG1451@1|root,COG1451@2|Bacteria,1R8SX@1224|Proteobacteria,42SNN@68525|delta/epsilon subdivisions,2WPQ4@28221|Deltaproteobacteria,2MK3B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
YHH2_k127_5910248_3	580332.Slit_0405	1.167e-217	679.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,44V6C@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
YHH2_k127_5910248_8	1163617.SCD_n00530	1.662e-103	340.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
YHH2_k127_5910248_5	580332.Slit_0409	7.003e-149	475.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria,44VMJ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
YHH2_k127_5910248_11	580332.Slit_0410	9.566e-21	95.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2WARD@28216|Betaproteobacteria,44W4B@713636|Nitrosomonadales	28216|Betaproteobacteria	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
YHH2_k127_5910248_13	1121422.AUMW01000010_gene1058	3.616e-05	50.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5910248_12	580332.Slit_0411	3.024e-12	66.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,44V6A@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c oxidase subunit I	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
YHH2_k127_5911407_2	580332.Slit_1809	4.377e-47	171.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,44V0E@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
YHH2_k127_5911407_1	580332.Slit_1808	3.038e-248	769.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,44V10@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YHH2_k127_5911407_0	580332.Slit_1807	9.876e-289	892.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,2VHA4@28216|Betaproteobacteria,44VA8@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
YHH2_k127_5950460_2	653733.Selin_0436	1.37e-71	256.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
YHH2_k127_5950460_1	1202962.KB907170_gene2407	1.189e-73	253.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
YHH2_k127_5950460_3	391615.ABSJ01000054_gene1466	2.436e-34	141.0	2EUFJ@1|root,33MXU@2|Bacteria,1NZHB@1224|Proteobacteria,1SQC7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
YHH2_k127_5950460_0	1485544.JQKP01000002_gene1351	2.056e-219	687.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44VDC@713636|Nitrosomonadales	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
YHH2_k127_5985140_0	580332.Slit_1486	1.386e-272	844.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,44V9N@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YHH2_k127_5985140_1	296591.Bpro_5346	2.276e-169	550.0	COG3677@1|root,COG3677@2|Bacteria,1R3VM@1224|Proteobacteria,2W1BX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5985140_2	580332.Slit_1523	3.505e-68	233.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VQR5@28216|Betaproteobacteria,44VXB@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
YHH2_k127_6026068_0	580332.Slit_1863	6.28e-153	495.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria,44VGB@713636|Nitrosomonadales	28216|Betaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH2_k127_6026068_1	395494.Galf_0700	1.357e-20	96.0	2BUWG@1|root,32Q8K@2|Bacteria,1PJWU@1224|Proteobacteria,2W88K@28216|Betaproteobacteria,44WJH@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2946
YHH2_k127_6040696_8	946483.Cenrod_1954	9.364e-34	132.0	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,2VTZN@28216|Betaproteobacteria,4AJJ3@80864|Comamonadaceae	28216|Betaproteobacteria	K	addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6040696_6	207559.Dde_0501	2.642e-35	141.0	COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,42V2I@68525|delta/epsilon subdivisions,2WRI9@28221|Deltaproteobacteria,2MDDA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM Addiction module killer protein	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
YHH2_k127_6040696_0	580332.Slit_0339	6.592e-218	678.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2VJA4@28216|Betaproteobacteria,44VCK@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
YHH2_k127_6040696_1	580332.Slit_0338	4.754e-167	529.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VJFX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Alcohol dehydrogenase zinc-binding domain protein	qor3	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
YHH2_k127_6040696_3	580332.Slit_0337	3.257e-121	394.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,2VH67@28216|Betaproteobacteria,44VAC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TatD related DNase	yjjV	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YHH2_k127_6040696_2	580332.Slit_0336	2.956e-140	448.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,2VJPP@28216|Betaproteobacteria,44V5M@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	moeB	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
YHH2_k127_6040696_5	580332.Slit_0335	1.375e-56	200.0	arCOG05276@1|root,3195F@2|Bacteria,1RHZA@1224|Proteobacteria,2VSYY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6040696_4	580332.Slit_0334	1.835e-68	236.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2VTZU@28216|Betaproteobacteria,44WH9@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
YHH2_k127_6040696_7	580332.Slit_0333	9.568e-35	133.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,44VCD@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Domain of unknown function (DUF3400)	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
YHH2_k127_6049850_1	580332.Slit_0896	1.622e-142	455.0	COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1Q14J@1224|Proteobacteria,2W9SH@28216|Betaproteobacteria,44WFR@713636|Nitrosomonadales	28216|Betaproteobacteria	H	TOBE domain	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	TOBE
YHH2_k127_6049850_6	62928.azo1372	9.344e-07	50.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_6049850_5	478741.JAFS01000001_gene1639	2.937e-107	352.0	COG0725@1|root,COG0725@2|Bacteria	2|Bacteria	P	tungstate binding	modA	GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168	-	ko:K02018,ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
YHH2_k127_6049850_3	243233.MCA1378	8.027e-121	392.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,1XE8A@135618|Methylococcales	1236|Gammaproteobacteria	P	molybdenum ABC transporter, periplasmic	modA-2	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
YHH2_k127_6049850_2	243233.MCA1379	2.893e-128	411.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1XEMM@135618|Methylococcales	135618|Methylococcales	P	ABC transporter permease protein	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
YHH2_k127_6049850_0	580332.Slit_0899	2.024e-159	510.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2VJ3B@28216|Betaproteobacteria,44W54@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TOBE domain	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
YHH2_k127_6049850_4	580332.Slit_0902	1.429e-115	378.0	2E2KC@1|root,32XPP@2|Bacteria,1R4ZI@1224|Proteobacteria,2VM8Z@28216|Betaproteobacteria,44WDX@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6066942_2	765913.ThidrDRAFT_0597	3.919e-212	662.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1X2PM@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4
YHH2_k127_6066942_6	977880.RALTA_A0600	1.063e-83	285.0	COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,2VQ5Z@28216|Betaproteobacteria,1K1U9@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379,ko:K18360	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	FdhD-NarQ
YHH2_k127_6066942_14	381666.H16_A0644	9.196e-15	79.0	2E4CR@1|root,32Z86@2|Bacteria,1N7UZ@1224|Proteobacteria,2VVR1@28216|Betaproteobacteria,1KA55@119060|Burkholderiaceae	28216|Betaproteobacteria	S	formate dehydrogenase	fdsD	-	1.17.1.9	ko:K00126	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	FdsD
YHH2_k127_6066942_11	5722.XP_001314717.1	8.614e-27	128.0	COG0666@1|root,KOG4177@2759|Eukaryota	5722.XP_001314717.1|-	I	spectrin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6066942_13	573370.DMR_05940	5.015e-21	93.0	COG1724@1|root,COG1724@2|Bacteria,1NMBX@1224|Proteobacteria	1224|Proteobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_6066942_8	1231391.AMZF01000001_gene2893	1.215e-43	162.0	COG1598@1|root,COG1598@2|Bacteria,1MZJQ@1224|Proteobacteria,2WFZF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB_lk_antitox
YHH2_k127_6066942_5	1163408.UU9_09042	7.618e-138	444.0	COG5380@1|root,COG5380@2|Bacteria,1QG74@1224|Proteobacteria	1224|Proteobacteria	O	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
YHH2_k127_6066942_18	1116472.MGMO_15c00060	6.949e-09	61.0	COG2161@1|root,COG2161@2|Bacteria,1QN17@1224|Proteobacteria,1TKDK@1236|Gammaproteobacteria,1XGUZ@135618|Methylococcales	135618|Methylococcales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_6066942_12	485917.Phep_2705	1.229e-23	105.0	COG1569@1|root,COG1569@2|Bacteria,4NX0E@976|Bacteroidetes	976|Bacteroidetes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH2_k127_6066942_3	443143.GM18_2280	6.237e-203	661.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg
YHH2_k127_6066942_10	1121374.KB891587_gene3036	5.383e-36	145.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_6066942_0	580332.Slit_0105	1.972e-308	951.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,44VJY@713636|Nitrosomonadales	28216|Betaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
YHH2_k127_6066942_9	580332.Slit_0104	2.085e-36	139.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,44VZQ@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PTS HPr component phosphorylation site	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
YHH2_k127_6066942_7	395494.Galf_0111	7.781e-49	179.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2VT9I@28216|Betaproteobacteria,44W0H@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	manX	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
YHH2_k127_6066942_4	580332.Slit_0101	6.139e-154	498.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,44VGN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	rnfF	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
YHH2_k127_6066942_1	1485544.JQKP01000002_gene1566	8.75e-235	730.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,2VHD9@28216|Betaproteobacteria,44V1Q@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Glutamate-cysteine ligase	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
YHH2_k127_6066942_17	1177179.A11A3_08085	2.508e-09	70.0	2ECI6@1|root,336GD@2|Bacteria,1NDNS@1224|Proteobacteria,1SEQ1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6077406_12	768671.ThimaDRAFT_4897	1.821e-19	89.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,1RRFT@1236|Gammaproteobacteria,1WZIC@135613|Chromatiales	135613|Chromatiales	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH2_k127_6077406_0	580332.Slit_1414	2.222e-229	713.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,44VKE@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
YHH2_k127_6077406_7	580332.Slit_1413	6.255e-51	194.0	COG1426@1|root,COG3266@1|root,COG1426@2|Bacteria,COG3266@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,44VYD@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Helix-turn-helix domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
YHH2_k127_6077406_5	580332.Slit_1412	6.117e-88	297.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,44VS2@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
YHH2_k127_6077406_1	580332.Slit_1411	3.816e-215	671.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,44V7I@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
YHH2_k127_6077406_6	395494.Galf_1398	1.528e-77	262.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,44VQP@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YHH2_k127_6077406_3	580332.Slit_1132	5.905e-171	545.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,44W94@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM NnrS family protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
YHH2_k127_6077406_14	1284775.HMPREF1640_13445	8.488e-12	76.0	2E631@1|root,330S3@2|Bacteria,4NYP5@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6077406_2	580332.Slit_1406	7.666e-192	611.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,44UY8@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
YHH2_k127_6077406_15	199310.c0222	1.468e-11	72.0	2E33Z@1|root,32Y42@2|Bacteria,1NDBD@1224|Proteobacteria,1SNMD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6077406_11	199310.c0222	5.277e-22	102.0	2E33Z@1|root,32Y42@2|Bacteria,1NDBD@1224|Proteobacteria,1SNMD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6077406_9	580332.Slit_1305	1.121e-29	119.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,44VIM@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH2_k127_6077406_4	580332.Slit_1305	4.014e-108	356.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,44VIM@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH2_k127_6077406_16	911008.GLAD_02928	4.717e-07	55.0	2EJR4@1|root,33DFY@2|Bacteria,1NJD5@1224|Proteobacteria,1ST4T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6077406_8	398578.Daci_3141	9.967e-35	136.0	2EC5K@1|root,33649@2|Bacteria,1NFQP@1224|Proteobacteria,2VXQY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6077406_10	1005048.CFU_2549	2.466e-24	104.0	COG4691@1|root,COG4691@2|Bacteria,1PXE0@1224|Proteobacteria,2WCUY@28216|Betaproteobacteria,4788X@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	-
YHH2_k127_6077406_13	1331060.RLDS_11260	1.201e-18	85.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6077551_30	580332.Slit_2445	6.375e-17	80.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,44V8P@713636|Nitrosomonadales	28216|Betaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
YHH2_k127_6077551_19	580332.Slit_2446	5.897e-76	256.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,44VVR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
YHH2_k127_6077551_27	580332.Slit_2447	3.283e-35	135.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,2VTZ4@28216|Betaproteobacteria,44W3A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
YHH2_k127_6077551_26	227377.CBU_1788	3.518e-50	186.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
YHH2_k127_6077551_18	316067.Geob_3253	1.127e-78	288.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YHH2_k127_6077551_31	580332.Slit_1550	7.886e-10	59.0	COG4680@1|root,COG4680@2|Bacteria,1N8JN@1224|Proteobacteria,2WAJH@28216|Betaproteobacteria,44WP0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
YHH2_k127_6077551_20	580332.Slit_1549	1.691e-73	250.0	COG5499@1|root,COG5499@2|Bacteria,1N89F@1224|Proteobacteria,2VWB3@28216|Betaproteobacteria,44WNE@713636|Nitrosomonadales	28216|Betaproteobacteria	K	SMART helix-turn-helix domain protein	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
YHH2_k127_6077551_16	316067.Geob_1191	1.238e-85	297.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42T4H@68525|delta/epsilon subdivisions,2WPIT@28221|Deltaproteobacteria,43U0U@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
YHH2_k127_6077551_2	580332.Slit_2449	4.908e-233	724.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,44V8E@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
YHH2_k127_6077551_5	580332.Slit_2450	1.621e-209	659.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria,44V44@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH2_k127_6077551_8	580332.Slit_2451	1.078e-178	572.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria,44V2W@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
YHH2_k127_6077551_22	580332.Slit_2452	3.561e-66	226.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,44VT4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
YHH2_k127_6077551_25	580332.Slit_2453	1.58e-55	198.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,44WIP@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Polymer-forming cytoskeletal	ccmA	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YHH2_k127_6077551_14	580332.Slit_2454	3.372e-100	333.0	28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VHRX@28216|Betaproteobacteria,44WF0@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6077551_6	580332.Slit_2455	3.103e-205	640.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,44V0R@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YHH2_k127_6077551_21	580332.Slit_2456	4.498e-70	238.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,44VSY@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
YHH2_k127_6077551_15	580332.Slit_2457	1.631e-90	299.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,44VQJ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YHH2_k127_6077551_4	580332.Slit_2458	2.863e-211	666.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2VICH@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
YHH2_k127_6077551_1	580332.Slit_2459	2.097e-259	807.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
YHH2_k127_6077551_12	580332.Slit_2460	1.25e-109	361.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
YHH2_k127_6077551_7	580332.Slit_2461	3.135e-186	587.0	COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,2VN24@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
YHH2_k127_6077551_0	580332.Slit_2462	1.292e-314	977.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,2VI53@28216|Betaproteobacteria,44VCU@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	yjcC	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
YHH2_k127_6077551_13	580332.Slit_2464	6.133e-106	350.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria,44W16@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH2_k127_6077551_10	580332.Slit_2465	8.543e-149	473.0	COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2VH4B@28216|Betaproteobacteria,44WCP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
YHH2_k127_6077551_24	395494.Galf_2791	4.232e-56	198.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,44WG1@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
YHH2_k127_6077551_23	555779.Dthio_PD1282	1.479e-65	226.0	COG2402@1|root,COG2402@2|Bacteria,1NCFK@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
YHH2_k127_6077551_11	1502724.FF80_03107	3.756e-111	369.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2TS7B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
YHH2_k127_6077551_3	580332.Slit_2467	6.891e-223	697.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2W931@28216|Betaproteobacteria,44WM2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH2_k127_6077551_33	1385515.N791_12545	1.949e-05	49.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1X32J@135614|Xanthomonadales	135614|Xanthomonadales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
YHH2_k127_6077551_17	580332.Slit_2468	1.966e-83	279.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,2VTYD@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
YHH2_k127_6077551_9	580332.Slit_2471	2.192e-161	512.0	2DJVG@1|root,307GH@2|Bacteria,1RG4V@1224|Proteobacteria,2VS8I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
YHH2_k127_6077551_29	1331060.RLDS_11260	1.201e-18	85.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6077672_0	580332.Slit_1548	3.609e-192	604.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2VH6A@28216|Betaproteobacteria,44WBM@713636|Nitrosomonadales	28216|Betaproteobacteria	K	SMART Resolvase RNase H domain protein fold	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
YHH2_k127_6077672_1	637389.Acaty_c1051	9.141e-41	154.0	COG3744@1|root,COG3744@2|Bacteria,1N2T0@1224|Proteobacteria,1S7NW@1236|Gammaproteobacteria,2ND71@225057|Acidithiobacillales	225057|Acidithiobacillales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_6077672_3	637389.Acaty_c1052	7.554e-18	85.0	COG4118@1|root,COG4118@2|Bacteria,1N7BG@1224|Proteobacteria,1T11V@1236|Gammaproteobacteria,2NE5B@225057|Acidithiobacillales	225057|Acidithiobacillales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_6077672_4	1410619.SRDD_08430	7.306e-16	80.0	2EAV9@1|root,334WR@2|Bacteria,1P4U3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6077672_2	1331060.RLDS_11260	1.201e-18	85.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6085873_1	1163617.SCD_n01884	4.303e-211	662.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,2VUBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Glucose inhibited division protein A	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored
YHH2_k127_6085873_0	1163617.SCD_n01883	0.0	1111.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,FlpD,Pyr_redox_2
YHH2_k127_6085873_2	1163617.SCD_n01882	5.835e-104	340.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,2W0PC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17
YHH2_k127_6085873_3	765911.Thivi_3111	1.035e-29	118.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,1SBBX@1236|Gammaproteobacteria,1X060@135613|Chromatiales	135613|Chromatiales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
YHH2_k127_6086261_10	640081.Dsui_3111	1.996e-35	152.0	COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,2VRRG@28216|Betaproteobacteria,2KVVA@206389|Rhodocyclales	206389|Rhodocyclales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
YHH2_k127_6086261_11	1492922.GY26_19855	1.837e-27	118.0	COG0226@1|root,COG0226@2|Bacteria,1N7RX@1224|Proteobacteria,1SCQW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type phosphate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6086261_3	857087.Metme_0062	4.501e-163	548.0	COG2202@1|root,COG2203@1|root,COG5000@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XFYJ@135618|Methylococcales	135618|Methylococcales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_4,PAS_9
YHH2_k127_6086261_7	1454004.AW11_02620	2.354e-54	207.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2VMG2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
YHH2_k127_6086261_6	365046.Rta_19280	6.02e-66	234.0	COG0745@1|root,COG0745@2|Bacteria,1N2T7@1224|Proteobacteria,2VSUA@28216|Betaproteobacteria,4AIKH@80864|Comamonadaceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH2_k127_6086261_8	365046.Rta_19290	4.706e-46	169.0	COG0745@1|root,COG0745@2|Bacteria	365046.Rta_19290|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6086261_9	365046.Rta_19310	5.717e-41	157.0	COG0835@1|root,COG0835@2|Bacteria,1Q0RG@1224|Proteobacteria,2W5MM@28216|Betaproteobacteria,4AIWF@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
YHH2_k127_6086261_4	365046.Rta_19320	3.825e-124	420.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2W05Y@28216|Betaproteobacteria,4AGS3@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	HAMP,MCPsignal,dCache_1
YHH2_k127_6086261_0	365046.Rta_19330	0.0	1118.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,4AGK7@80864|Comamonadaceae	28216|Betaproteobacteria	T	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW,HATPase_c,Hpt,Response_reg
YHH2_k127_6086261_14	1249627.D779_2645	6.044e-08	61.0	2EVMX@1|root,33P1X@2|Bacteria,1NK24@1224|Proteobacteria,1SIT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CheW
YHH2_k127_6086261_1	580332.Slit_0650	1.41e-256	792.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,44V8Z@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
YHH2_k127_6086261_5	580332.Slit_0651	1.354e-82	276.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,44VU0@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
YHH2_k127_6086261_2	580332.Slit_0652	8.683e-166	529.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,44VG2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
YHH2_k127_6182275_0	1304885.AUEY01000001_gene3308	0.0005241	53.0	COG1704@1|root,COG1704@2|Bacteria,1RF5E@1224|Proteobacteria,42S8B@68525|delta/epsilon subdivisions,2WNYZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	E3 Ubiquitin ligase	-	-	-	-	-	-	-	-	-	-	-	-	GIDE
YHH2_k127_6186142_7	159087.Daro_2896	2.393e-68	237.0	COG2267@1|root,COG2267@2|Bacteria,1R41P@1224|Proteobacteria,2WGZC@28216|Betaproteobacteria,2KXE7@206389|Rhodocyclales	206389|Rhodocyclales	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YHH2_k127_6186142_13	580332.Slit_1614	2.549e-28	119.0	2FBSW@1|root,343XP@2|Bacteria,1P3U4@1224|Proteobacteria,2W4AY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6186142_9	1232410.KI421428_gene1088	2.53e-52	191.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,42TA9@68525|delta/epsilon subdivisions,2WPHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
YHH2_k127_6186142_5	580332.Slit_0927	2.545e-98	323.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria,44VST@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
YHH2_k127_6186142_2	580332.Slit_2526	7.321e-191	600.0	COG0387@1|root,COG0387@2|Bacteria,1MWD8@1224|Proteobacteria,2VJQM@28216|Betaproteobacteria,44V5W@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
YHH2_k127_6186142_8	1209072.ALBT01000044_gene2518	1.663e-59	211.0	29A26@1|root,2ZX3K@2|Bacteria,1RFE8@1224|Proteobacteria,1S7AB@1236|Gammaproteobacteria,1FI97@10|Cellvibrio	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6186142_6	1121035.AUCH01000005_gene1	4.698e-91	304.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria	1224|Proteobacteria	S	PFAM peptidase M28	yfbL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YHH2_k127_6186142_16	522306.CAP2UW1_1010	6.106e-17	84.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria	1224|Proteobacteria	S	PFAM peptidase M28	yfbL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YHH2_k127_6186142_0	580332.Slit_2315	5.833e-267	828.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,44W50@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function DUF87	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
YHH2_k127_6186142_14	631362.Thi970DRAFT_03920	3.278e-24	104.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442,HNH_5,HTH_3,HTH_31
YHH2_k127_6186142_12	631362.Thi970DRAFT_03919	3.41e-45	166.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,1WZ7T@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
YHH2_k127_6186142_10	1562701.BBOF01000065_gene2113	1.629e-51	186.0	COG2337@1|root,COG2337@2|Bacteria,1RI5U@1224|Proteobacteria,2WG14@28216|Betaproteobacteria,1KFT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K18841	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH2_k127_6186142_15	1562701.BBOF01000065_gene2112	5.348e-24	103.0	COG2336@1|root,COG2336@2|Bacteria,1NJ97@1224|Proteobacteria,2W5AV@28216|Betaproteobacteria,1KB5S@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM SpoVT AbrB	-	-	-	ko:K18842	-	-	-	-	ko00000,ko02048	-	-	-	-
YHH2_k127_6186142_19	1076550.LH22_07955	1.36e-06	50.0	COG3183@1|root,COG3183@2|Bacteria	2|Bacteria	L	HNH endonuclease	-	-	-	ko:K07451,ko:K07453	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
YHH2_k127_6186142_3	1166130.H650_00655	1.254e-113	377.0	COG0210@1|root,COG0210@2|Bacteria,1R5VM@1224|Proteobacteria,1RRUI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase
YHH2_k127_6186142_1	1166130.H650_00660	6.889e-230	722.0	COG3950@1|root,COG3950@2|Bacteria,1MYQ2@1224|Proteobacteria,1RNXR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Conjugative transposon DNA recombination protein	-	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	AAA_15,AAA_21
YHH2_k127_6186142_4	395494.Galf_1586	4.584e-109	370.0	COG0457@1|root,COG0457@2|Bacteria	395494.Galf_1586|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6186142_11	1163617.SCD_n00730	1.069e-47	174.0	2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,2VWT7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6186142_18	1163617.SCD_n00731	2.863e-08	58.0	COG0457@1|root,COG0457@2|Bacteria,1QV5B@1224|Proteobacteria,2WGRP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16
YHH2_k127_6193798_8	886293.Sinac_0066	1.613e-39	160.0	COG3921@1|root,COG3921@2|Bacteria,2J1YT@203682|Planctomycetes	203682|Planctomycetes	S	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
YHH2_k127_6193798_2	926550.CLDAP_28810	3.066e-140	453.0	COG4974@1|root,COG4974@2|Bacteria,2G7RJ@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
YHH2_k127_6193798_7	398512.JQKC01000019_gene3396	2.304e-50	188.0	COG1073@1|root,COG1073@2|Bacteria,1V38K@1239|Firmicutes,24AHG@186801|Clostridia,3WMIG@541000|Ruminococcaceae	186801|Clostridia	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Bile_Hydr_Trans
YHH2_k127_6193798_10	694427.Palpr_2522	5.382e-19	98.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,2FP0D@200643|Bacteroidia,22WMR@171551|Porphyromonadaceae	976|Bacteroidetes	S	Hydrolase, alpha beta domain protein	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
YHH2_k127_6193798_1	580332.Slit_1752	1.212e-215	675.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
YHH2_k127_6193798_5	580332.Slit_1751	1.213e-85	298.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2VRIQ@28216|Betaproteobacteria,44VVJ@713636|Nitrosomonadales	28216|Betaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
YHH2_k127_6193798_4	580332.Slit_1750	2.165e-118	390.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2VI54@28216|Betaproteobacteria,44VF1@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	ABC transporter	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_6193798_9	1458357.BG58_37305	3.004e-28	115.0	COG4456@1|root,COG4456@2|Bacteria,1N2HQ@1224|Proteobacteria,2VW5X@28216|Betaproteobacteria,1K9NN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SpoVT AbrB	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_6193798_6	426114.THI_1946	1.705e-55	196.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,2VRST@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH2_k127_6193798_0	580332.Slit_1377	5.602e-229	711.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,44VH2@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH2_k127_6193798_3	580332.Slit_1748	1.653e-130	424.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,44VBM@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_6201561_2	1434929.X946_3406	1.375e-135	442.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,2W0JF@28216|Betaproteobacteria,1K61Q@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
YHH2_k127_6201561_0	1112274.KI911560_gene1066	0.0	1579.0	COG3513@1|root,COG3513@2|Bacteria,1MVT9@1224|Proteobacteria,2VJ7J@28216|Betaproteobacteria	28216|Betaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer	cas9	-	-	ko:K09952	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH_4
YHH2_k127_6201561_1	1304883.KI912532_gene2379	1.331e-135	438.0	COG1518@1|root,COG1518@2|Bacteria,1MX9W@1224|Proteobacteria,2VNWK@28216|Betaproteobacteria	28216|Betaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
YHH2_k127_6201561_3	1223521.BBJX01000015_gene221	2.901e-47	171.0	COG3512@1|root,COG3512@2|Bacteria,1N08B@1224|Proteobacteria,2VTET@28216|Betaproteobacteria,4AHR8@80864|Comamonadaceae	28216|Betaproteobacteria	L	CRISPR associated protein Cas2	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
YHH2_k127_6208031_5	580332.Slit_0289	7.81e-112	364.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,44VQC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
YHH2_k127_6208031_2	580332.Slit_0290	2.809e-209	655.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,44V5S@713636|Nitrosomonadales	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiF	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,SE
YHH2_k127_6208031_3	580332.Slit_0291	1.964e-192	603.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,44UYZ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
YHH2_k127_6208031_10	580332.Slit_0292	1.869e-40	151.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria,44W2K@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory protein, Fis family	fis	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
YHH2_k127_6208031_0	580332.Slit_0293	3.975e-306	945.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,44VKQ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme formylation region	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
YHH2_k127_6208031_16	1116472.MGMO_122c00110	1.982e-21	95.0	COG5428@1|root,COG5428@2|Bacteria,1N7FH@1224|Proteobacteria,1SCVZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
YHH2_k127_6208031_12	29495.EA26_14530	3.532e-34	142.0	2DPCB@1|root,331HJ@2|Bacteria,1NED4@1224|Proteobacteria,1SGZF@1236|Gammaproteobacteria,1XYAZ@135623|Vibrionales	135623|Vibrionales	S	Putative phage abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	putAbiC
YHH2_k127_6208031_15	76114.ebD37	1.853e-30	124.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	HEPN,NTP_transf_2
YHH2_k127_6208031_17	1163617.SCD_n01378	1.879e-16	85.0	COG2250@1|root,COG2250@2|Bacteria,1NGJT@1224|Proteobacteria,2W5VI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
YHH2_k127_6208031_1	580332.Slit_0294	9.571e-251	777.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,44V8B@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YHH2_k127_6208031_18	1381123.AYOD01000060_gene1620	1.793e-11	67.0	COG4456@1|root,COG4456@2|Bacteria,1N6Y0@1224|Proteobacteria,2UFCI@28211|Alphaproteobacteria,43MJT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_6208031_13	240015.ACP_0134	4.129e-31	128.0	COG1487@1|root,COG1487@2|Bacteria,3Y5X8@57723|Acidobacteria,2JK5Q@204432|Acidobacteriia	204432|Acidobacteriia	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH2_k127_6208031_7	580332.Slit_0295	4.216e-90	299.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,44VTE@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
YHH2_k127_6208031_4	580332.Slit_0296	2.338e-178	560.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,44VJH@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
YHH2_k127_6208031_6	580332.Slit_0297	7.867e-94	311.0	COG0500@1|root,COG0500@2|Bacteria,1REJ2@1224|Proteobacteria,2VQ90@28216|Betaproteobacteria,44W5P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YHH2_k127_6208031_14	1163617.SCD_n01005	1.094e-30	123.0	2E5AT@1|root,3302X@2|Bacteria,1N70A@1224|Proteobacteria,2VVZT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6208031_11	1163617.SCD_n01004	2.444e-39	151.0	COG3041@1|root,COG3041@2|Bacteria,1NBQC@1224|Proteobacteria,2VUXW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Addiction module toxin RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6208031_19	977880.RALTA_A1744	6.053e-07	55.0	COG2336@1|root,COG2336@2|Bacteria,1NFRR@1224|Proteobacteria,2W4U5@28216|Betaproteobacteria,1K973@119060|Burkholderiaceae	28216|Betaproteobacteria	T	antitoxin	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_6208031_9	637390.AFOH01000113_gene2913	5.029e-46	172.0	COG2337@1|root,COG2337@2|Bacteria,1PVJ7@1224|Proteobacteria,1T93T@1236|Gammaproteobacteria,2NDUW@225057|Acidithiobacillales	225057|Acidithiobacillales	L	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH2_k127_6208031_8	580332.Slit_0902	2.597e-62	215.0	2E2KC@1|root,32XPP@2|Bacteria,1R4ZI@1224|Proteobacteria,2VM8Z@28216|Betaproteobacteria,44WDX@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6215819_1	671143.DAMO_1538	3.801e-26	117.0	COG0668@1|root,COG0668@2|Bacteria,2NQ6B@2323|unclassified Bacteria	2|Bacteria	M	transmembrane transport	cmpX	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
YHH2_k127_6215819_0	909663.KI867151_gene3008	2.521e-170	544.0	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria,2MR35@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
YHH2_k127_6215819_2	580332.Slit_1785	1.188e-17	83.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2VHXK@28216|Betaproteobacteria	28216|Betaproteobacteria	G	hydroxypyruvate reductase	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
YHH2_k127_6216016_0	580332.Slit_1879	2.283e-132	424.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VKFG@28216|Betaproteobacteria,44VP1@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
YHH2_k127_6216016_3	1117314.PCIT_05492	1.153e-64	232.0	2C5WH@1|root,32DGW@2|Bacteria,1MYXR@1224|Proteobacteria,1S6GZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (Hypoth_ymh)	-	-	-	-	-	-	-	-	-	-	-	-	Hypoth_Ymh
YHH2_k127_6216016_1	580332.Slit_1558	1.758e-81	277.0	arCOG05203@1|root,31A0K@2|Bacteria,1RHZR@1224|Proteobacteria,2VX85@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6216016_2	264198.Reut_A0185	1.474e-80	274.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2VQH1@28216|Betaproteobacteria,1KGNN@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Transcriptional regulatory protein, C terminal	creB	-	-	ko:K07663	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_6216016_4	1120999.JONM01000004_gene3533	2.406e-64	229.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2VH7Q@28216|Betaproteobacteria,2KQS7@206351|Neisseriales	206351|Neisseriales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
YHH2_k127_6221029_15	395495.Lcho_1542	1.424e-102	354.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2VJ8G@28216|Betaproteobacteria,1KNFS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
YHH2_k127_6221029_17	580332.Slit_0868	5.498e-70	253.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2VJ8G@28216|Betaproteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Cytochrome_C7,Paired_CXXCH_1
YHH2_k127_6221029_6	580332.Slit_0867	3.974e-197	638.0	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,2VNYC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6221029_16	395494.Galf_1434	8.861e-77	266.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2VIAA@28216|Betaproteobacteria,44W4P@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
YHH2_k127_6221029_8	580332.Slit_1602	1.231e-148	471.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,2VKZ3@28216|Betaproteobacteria,44WHN@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_6221029_21	395495.Lcho_1566	2.575e-23	101.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	DUF2281,PhdYeFM_antitox
YHH2_k127_6221029_19	251221.35214127	7.075e-45	166.0	COG3744@1|root,COG3744@2|Bacteria,1G89C@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_6221029_4	580332.Slit_0526	1.107e-216	676.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,44UZH@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
YHH2_k127_6221029_7	580332.Slit_0527	2.876e-181	569.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,44V0Q@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
YHH2_k127_6221029_14	580332.Slit_0528	4.747e-111	363.0	COG0861@1|root,COG0861@2|Bacteria,1MXSK@1224|Proteobacteria,2VHZ5@28216|Betaproteobacteria,44VMY@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
YHH2_k127_6221029_18	580332.Slit_0529	6.841e-65	224.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria,2VUAF@28216|Betaproteobacteria,44VW3@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YHH2_k127_6221029_1	580332.Slit_0530	0.0	1424.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
YHH2_k127_6221029_9	580332.Slit_0531	1.758e-141	452.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,44W64@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART protein phosphatase 2C domain protein	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
YHH2_k127_6221029_13	580332.Slit_0532	2.125e-112	368.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,44WCZ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
YHH2_k127_6221029_2	580332.Slit_0533	0.0	1155.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
YHH2_k127_6221029_10	580332.Slit_0534	2.44e-130	420.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,44W4T@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SMART beta-lactamase domain protein	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
YHH2_k127_6221029_0	580332.Slit_0536	0.0	1425.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44VNC@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	GAF,T2SSE,T2SSE_N
YHH2_k127_6221029_3	580332.Slit_0537	1.825e-277	860.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,44W5N@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
YHH2_k127_6221029_20	395494.Galf_2551	2.685e-44	166.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria,44W47@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
YHH2_k127_6221029_12	697282.Mettu_1381	3.795e-118	400.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria	1224|Proteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
YHH2_k127_6221029_22	509190.Cseg_3813	3.989e-19	94.0	COG4704@1|root,COG4704@2|Bacteria,1N6RE@1224|Proteobacteria,2UFAH@28211|Alphaproteobacteria,2KHA1@204458|Caulobacterales	204458|Caulobacterales	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
YHH2_k127_6221029_11	580332.Slit_2575	1.581e-127	413.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VR8F@28216|Betaproteobacteria,44WB0@713636|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_6221029_5	580332.Slit_2574	2.356e-214	671.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,2VP40@28216|Betaproteobacteria,44W53@713636|Nitrosomonadales	28216|Betaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_6288264_0	580332.Slit_1999	1.119e-93	314.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,44VIY@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
YHH2_k127_6288264_2	404380.Gbem_2143	4.49e-16	93.0	COG1404@1|root,COG1404@2|Bacteria,1REF1@1224|Proteobacteria,42Q4N@68525|delta/epsilon subdivisions,2WS51@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6,Peptidase_S8
YHH2_k127_6288264_1	1266925.JHVX01000002_gene989	3.445e-82	281.0	COG3675@1|root,COG3675@2|Bacteria,1ND8U@1224|Proteobacteria,2W674@28216|Betaproteobacteria,374IY@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
YHH2_k127_6310688_6	395494.Galf_1152	6.778e-24	102.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,44V6M@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
YHH2_k127_6310688_2	580332.Slit_2055	2.045e-177	558.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2VHNS@28216|Betaproteobacteria,44VK8@713636|Nitrosomonadales	28216|Betaproteobacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272,ko:K21344	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
YHH2_k127_6310688_4	580332.Slit_2056	6.6e-119	386.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2VJRD@28216|Betaproteobacteria,44VEZ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
YHH2_k127_6310688_1	580332.Slit_2057	2.202e-212	664.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria,44UYA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_7
YHH2_k127_6310688_5	580332.Slit_2058	7.974e-37	144.0	COG5416@1|root,COG5416@2|Bacteria,1N4UI@1224|Proteobacteria,2VU63@28216|Betaproteobacteria,44W2U@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Pfam:DUF1049	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
YHH2_k127_6310688_0	580332.Slit_2093	5.916e-269	841.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,44V5K@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YHH2_k127_6310688_3	580332.Slit_2094	7.818e-146	466.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,44VJE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
YHH2_k127_634258_1	1485544.JQKP01000015_gene2071	0.0	1026.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,44V5A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
YHH2_k127_634258_2	580332.Slit_1481	1.044e-286	884.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2VH2X@28216|Betaproteobacteria,44VCN@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
YHH2_k127_634258_4	580332.Slit_1480	4.042e-74	252.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,44VTX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
YHH2_k127_634258_3	580332.Slit_0831	1.187e-81	274.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2VU86@28216|Betaproteobacteria,44WF8@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Peptidase S24 S26A S26B, conserved region	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
YHH2_k127_634258_5	580332.Slit_1397	1.712e-72	248.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2VSHR@28216|Betaproteobacteria,44VXR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
YHH2_k127_634258_0	580332.Slit_1396	0.0	1053.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,44UYC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
YHH2_k127_634258_7	214092.YPO0791	9.888e-21	96.0	2E913@1|root,333AD@2|Bacteria,1NF8W@1224|Proteobacteria,1SF87@1236|Gammaproteobacteria,41HHP@629|Yersinia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_634258_6	1121004.ATVC01000014_gene2027	1.655e-35	136.0	COG3093@1|root,COG3093@2|Bacteria,1N2BD@1224|Proteobacteria,2VVV1@28216|Betaproteobacteria,2KRZQ@206351|Neisseriales	206351|Neisseriales	K	Helix-turn-helix	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
YHH2_k127_6365266_2	859657.RPSI07_0989	1.618e-120	393.0	COG3012@1|root,COG3012@2|Bacteria,1RBI1@1224|Proteobacteria,2VRNT@28216|Betaproteobacteria,1KEGA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SEC-C Motif Domain Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6365266_0	580332.Slit_0815	2.023e-215	677.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VMTA@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
YHH2_k127_6365266_3	580332.Slit_0816	2.042e-84	282.0	COG3090@1|root,COG3090@2|Bacteria,1PJMD@1224|Proteobacteria,2VYB1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
YHH2_k127_6365266_1	580332.Slit_0817	2.3e-161	514.0	COG1638@1|root,COG1638@2|Bacteria,1PN6J@1224|Proteobacteria,2VSNQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
YHH2_k127_6375408_14	1116472.MGMO_66c00250	6.67e-12	66.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1XEGS@135618|Methylococcales	135618|Methylococcales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YHH2_k127_6375408_7	583345.Mmol_0390	1.793e-45	166.0	COG3070@1|root,COG3070@2|Bacteria,1N0ND@1224|Proteobacteria,2VWJJ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	TfoX, N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
YHH2_k127_6375408_4	497964.CfE428DRAFT_4783	3.351e-97	331.0	COG3214@1|root,COG3214@2|Bacteria,46UTW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
YHH2_k127_6375408_6	338969.Rfer_0151	3.671e-73	253.0	COG2378@1|root,COG2378@2|Bacteria,1MXS8@1224|Proteobacteria,2VP6N@28216|Betaproteobacteria,4AEAT@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM Helix-turn-helix, type 11 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
YHH2_k127_6375408_12	266835.14023517	2.585e-24	104.0	COG4430@1|root,COG4430@2|Bacteria,1NASK@1224|Proteobacteria,2UIVY@28211|Alphaproteobacteria,43M57@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
YHH2_k127_6375408_1	204773.HEAR2526	1.216e-222	698.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2VHA5@28216|Betaproteobacteria,472U1@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
YHH2_k127_6375408_3	580332.Slit_1782	5.674e-104	347.0	COG0784@1|root,COG3437@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HATPase_c,HisKA,Response_reg
YHH2_k127_6375408_2	580332.Slit_1783	9.656e-181	576.0	COG0517@1|root,COG4191@1|root,COG0517@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,HATPase_c,HisKA,Response_reg,dCache_1
YHH2_k127_6375408_0	395494.Galf_1809	0.0	1559.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,44VJZ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH2_k127_6375408_5	443144.GM21_2726	1.725e-80	282.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,42MWV@68525|delta/epsilon subdivisions,2WJJZ@28221|Deltaproteobacteria,43SI6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Fic/DOC family N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
YHH2_k127_6375408_13	640512.BC1003_3357	3.56e-23	100.0	COG1724@1|root,COG1724@2|Bacteria,1N7S3@1224|Proteobacteria,2VXPF@28216|Betaproteobacteria,1KAGD@119060|Burkholderiaceae	28216|Betaproteobacteria	N	PFAM YcfA family protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_6375408_8	640510.BC1001_3400	1.315e-42	164.0	COG0864@1|root,COG1598@1|root,COG0864@2|Bacteria,COG1598@2|Bacteria,1N3KE@1224|Proteobacteria,2VVKB@28216|Betaproteobacteria,1K7E0@119060|Burkholderiaceae	28216|Betaproteobacteria	K	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
YHH2_k127_6375408_10	395494.Galf_0937	2.158e-35	138.0	2DNER@1|root,32X4S@2|Bacteria,1NB0B@1224|Proteobacteria,2VWJQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ParD-like antitoxin of type II bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	ParD_like
YHH2_k127_6375408_11	1255043.TVNIR_3868	6.093e-32	126.0	COG2442@1|root,COG2442@2|Bacteria,1N8Z1@1224|Proteobacteria,1SEX2@1236|Gammaproteobacteria,1X23W@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YHH2_k127_6375408_9	331113.SNE_A02220	1.298e-36	156.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH2_k127_6389587_3	927658.AJUM01000037_gene1858	5.245e-16	91.0	COG0642@1|root,COG2205@2|Bacteria,4PHK6@976|Bacteroidetes,2FY0M@200643|Bacteroidia,3XKU6@558415|Marinilabiliaceae	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6389587_1	1132855.KB913035_gene1182	1.222e-59	222.0	COG2202@1|root,COG3852@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9
YHH2_k127_6389587_2	666681.M301_1663	1.049e-51	193.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VM61@28216|Betaproteobacteria	28216|Betaproteobacteria	K	response regulator	-	-	-	ko:K13041	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
YHH2_k127_6389587_0	580332.Slit_1339	1.319e-143	461.0	COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,2VJMU@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	of the drug metabolite transporter (DMT) superfamily	eamA1	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH2_k127_6393910_0	580332.Slit_1644	2.177e-220	689.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,44V27@713636|Nitrosomonadales	28216|Betaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
YHH2_k127_6393910_1	580332.Slit_1645	3.933e-211	662.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,44V71@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
YHH2_k127_6393910_5	395494.Galf_1788	3.092e-100	333.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria,44VDE@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Cytidylyltransferase family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
YHH2_k127_6393910_3	580332.Slit_1647	2.131e-139	445.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,44V2T@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
YHH2_k127_6393910_4	580332.Slit_1648	3.713e-102	334.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,44VJI@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
YHH2_k127_6393910_2	580332.Slit_1649	1.815e-139	444.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,44VAA@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YHH2_k127_6393910_6	580332.Slit_1650	5.392e-23	98.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,44VIJ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
YHH2_k127_6423104_2	580332.Slit_2687	4.747e-117	381.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,44VCV@713636|Nitrosomonadales	28216|Betaproteobacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
YHH2_k127_6423104_3	204773.HEAR2463	2.297e-102	341.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,473EN@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	branched-chain amino acid	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
YHH2_k127_6423104_0	580332.Slit_2690	1.961e-206	661.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,44VMH@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
YHH2_k127_6423104_1	580332.Slit_2691	3.224e-165	523.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,44VDS@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
YHH2_k127_6423104_4	62928.azo1372	4.471e-07	51.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_6503732_3	395494.Galf_0032	1.233e-212	662.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2VHGI@28216|Betaproteobacteria,44V7P@713636|Nitrosomonadales	28216|Betaproteobacteria	G	TIGRFAM fructose-bisphosphate aldolase, class II, Calvin cycle subtype	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
YHH2_k127_6503732_1	580332.Slit_0017	2.856e-274	847.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,44VCT@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the pyruvate kinase family	pykA	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
YHH2_k127_6503732_2	580332.Slit_0016	9.449e-235	729.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,44VJU@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
YHH2_k127_6503732_4	1163617.SCD_n02845	3.88e-199	622.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
YHH2_k127_6503732_0	580332.Slit_0014	0.0	1298.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,44VJX@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
YHH2_k127_6504416_0	580332.Slit_0343	8.857e-301	928.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,44VIR@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH2_k127_6504416_1	580332.Slit_0344	1.672e-215	678.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2WHEI@28216|Betaproteobacteria,44UZ2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH2_k127_6504416_2	292415.Tbd_0039	1.505e-30	123.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2VW5V@28216|Betaproteobacteria,1KRS0@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein L31	-	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
YHH2_k127_6506250_7	580332.Slit_1282	2.446e-12	67.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,44VQ8@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YHH2_k127_6506250_1	580332.Slit_1283	9.813e-173	546.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,44VDI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
YHH2_k127_6506250_4	1485544.JQKP01000003_gene269	4.092e-116	377.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria,44V76@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
YHH2_k127_6506250_3	580332.Slit_1285	9.517e-132	424.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,44VH1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
YHH2_k127_6506250_6	1485544.JQKP01000003_gene267	2.008e-50	181.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2VT0P@28216|Betaproteobacteria,44VYY@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
YHH2_k127_6506250_0	580332.Slit_1172	5.714e-175	551.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,44VI4@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH2_k127_6506250_5	1163617.SCD_n00755	2.375e-57	202.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,2VR6M@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	nikR	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
YHH2_k127_6506250_2	748247.AZKH_3784	4.265e-164	527.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KV0D@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	hoxJ	-	2.7.13.3	ko:K19661	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4
YHH2_k127_6531979_4	28072.Nos7524_3633	4.342e-05	47.0	COG3547@1|root,COG3547@2|Bacteria,1GA7N@1117|Cyanobacteria,1HTM7@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH2_k127_6531979_2	1120950.KB892746_gene3541	1.11e-22	100.0	COG3467@1|root,COG3467@2|Bacteria,2IR80@201174|Actinobacteria,4DS49@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
YHH2_k127_6531979_0	457429.ABJI02000827_gene2456	7.553e-67	238.0	COG0702@1|root,COG0702@2|Bacteria,2GK1A@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
YHH2_k127_6531979_1	315730.BcerKBAB4_2261	1.88e-29	121.0	2DNMG@1|root,32Y46@2|Bacteria,1VK1T@1239|Firmicutes,4HNYW@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6544115_15	671143.DAMO_1317	7.689e-13	79.0	COG4191@1|root,COG4252@1|root,COG4191@2|Bacteria,COG4252@2|Bacteria,2NP7Y@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	phoR_2	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HATPase_c,HisKA,PAS_4
YHH2_k127_6544115_16	1385935.N836_28475	3.987e-05	55.0	COG4254@1|root,COG4254@2|Bacteria,1G662@1117|Cyanobacteria,1HA7R@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
YHH2_k127_6544115_7	929703.KE386491_gene3970	3.791e-111	363.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,47KHR@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
YHH2_k127_6544115_13	383372.Rcas_3080	1.944e-51	185.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH2_k127_6544115_3	105559.Nwat_1158	5.861e-177	580.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,1WWBJ@135613|Chromatiales	135613|Chromatiales	M	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH2_k127_6544115_10	580332.Slit_2398	1.044e-80	273.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,44VU7@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
YHH2_k127_6544115_8	580332.Slit_2399	1.444e-88	299.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,44WG0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cobalamin adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
YHH2_k127_6544115_17	5722.XP_001318095.1	0.0009413	52.0	COG0666@1|root,KOG4177@2759|Eukaryota	5722.XP_001318095.1|-	I	spectrin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6544115_14	580332.Slit_2399	1.779e-22	98.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,44WG0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cobalamin adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
YHH2_k127_6544115_5	580332.Slit_2400	8.133e-143	455.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,44VGT@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
YHH2_k127_6544115_6	580332.Slit_2401	2.015e-119	386.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2VHHT@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
YHH2_k127_6544115_2	580332.Slit_2402	1.077e-209	653.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2VIQ5@28216|Betaproteobacteria,44V1V@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
YHH2_k127_6544115_9	580332.Slit_2403	6.973e-88	291.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,44VPP@713636|Nitrosomonadales	28216|Betaproteobacteria	E	ACT domain	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
YHH2_k127_6544115_0	580332.Slit_2404	0.0	1079.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,44V6P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM thiamine pyrophosphate	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YHH2_k127_6544115_12	580332.Slit_2405	2.796e-73	253.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,2VQ28@28216|Betaproteobacteria,44VVF@713636|Nitrosomonadales	28216|Betaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_6544115_4	580332.Slit_2222	1.544e-162	518.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria,44WBQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YHH2_k127_6544115_1	580332.Slit_2223	8.451e-307	950.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,44WEH@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
YHH2_k127_6544115_11	1485544.JQKP01000005_gene355	3.651e-79	265.0	COG0720@1|root,COG0720@2|Bacteria,1RETG@1224|Proteobacteria,2VRBN@28216|Betaproteobacteria,44VRF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
YHH2_k127_6589275_1	580332.Slit_1254	1.492e-147	471.0	COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,2VN44@28216|Betaproteobacteria,44VEW@713636|Nitrosomonadales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH2_k127_6589275_9	1120999.JONM01000001_gene1046	1.488e-14	85.0	COG4254@1|root,COG4254@2|Bacteria,1NBPR@1224|Proteobacteria,2WAQS@28216|Betaproteobacteria,2KTMM@206351|Neisseriales	1224|Proteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
YHH2_k127_6589275_5	1173027.Mic7113_3264	2.05e-89	310.0	COG0642@1|root,COG2205@2|Bacteria,1G06M@1117|Cyanobacteria,1H95E@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YHH2_k127_6589275_4	551115.Aazo_2223	7.342e-103	339.0	COG0745@1|root,COG0745@2|Bacteria,1G16W@1117|Cyanobacteria,1HK4M@1161|Nostocales	1117|Cyanobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_6589275_10	1049564.TevJSym_ae01160	1.762e-12	73.0	2EBCA@1|root,335D0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
YHH2_k127_6589275_3	1049564.TevJSym_ae01150	1.8e-122	405.0	COG0151@1|root,COG0151@2|Bacteria,1RB1U@1224|Proteobacteria,1S9GX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6589275_0	1049564.TevJSym_ae01130	2.186e-183	586.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1S3F2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Orn DAP Arg decarboxylase	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YHH2_k127_6589275_2	1485545.JQLW01000005_gene1190	2.495e-126	433.0	COG0739@1|root,COG4413@1|root,COG0739@2|Bacteria,COG4413@2|Bacteria,1MXH6@1224|Proteobacteria	1224|Proteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,UT
YHH2_k127_6589275_11	765420.OSCT_0903	0.0004981	44.0	COG1287@1|root,COG1287@2|Bacteria,2G8R6@200795|Chloroflexi,377ZY@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6589275_6	1049564.TevJSym_ae01080	3.718e-50	185.0	COG0457@1|root,COG0457@2|Bacteria,1NWHJ@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_2,TPR_6
YHH2_k127_6589275_8	640081.Dsui_1244	5.613e-40	165.0	COG0457@1|root,COG0457@2|Bacteria	640081.Dsui_1244|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6602838_0	118166.JH976537_gene3690	3.238e-42	169.0	COG3385@1|root,2ZA2Q@2|Bacteria,1G4UP@1117|Cyanobacteria	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH2_k127_6602838_2	471874.PROSTU_00598	9.243e-16	79.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1S9EI@1236|Gammaproteobacteria,3ZABT@586|Providencia	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
YHH2_k127_6602838_1	323848.Nmul_A0109	1.572e-37	151.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2VM41@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve_3
YHH2_k127_6628483_0	580332.Slit_2363	6.46e-256	812.0	COG2199@1|root,COG2703@1|root,COG2199@2|Bacteria,COG2703@2|Bacteria,1PFQT@1224|Proteobacteria,2W8ZM@28216|Betaproteobacteria,44WDT@713636|Nitrosomonadales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	GGDEF,PAS_3
YHH2_k127_6628483_4	580332.Slit_2364	5.193e-50	177.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,44W12@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
YHH2_k127_6628483_3	580332.Slit_2365	3.882e-82	276.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,44VPS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YHH2_k127_6628483_2	580332.Slit_2366	6.022e-87	291.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,44VUP@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
YHH2_k127_6628483_1	580332.Slit_2367	1.27e-206	649.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria,44UZ0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH2_k127_6652076_3	580332.Slit_2349	1.249e-99	327.0	COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,2VQ9D@28216|Betaproteobacteria,44WFP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1415)	-	-	-	ko:K09941	-	-	-	-	ko00000	-	-	-	DUF1415
YHH2_k127_6652076_4	395494.Galf_0421	1.676e-59	209.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,2VUM5@28216|Betaproteobacteria,44VVX@713636|Nitrosomonadales	28216|Betaproteobacteria	S	membrane	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH2_k127_6652076_2	580332.Slit_2508	1.06e-99	332.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,44VSN@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
YHH2_k127_6652076_0	261292.Nit79A3_3071	9.015e-270	841.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,372TA@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	lpdA	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
YHH2_k127_6652076_1	580332.Slit_2506	1.57e-229	715.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,44V7E@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH2_k127_6652076_5	580332.Slit_2505	3.989e-06	49.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,44V9E@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
YHH2_k127_6725948_4	314345.SPV1_10851	6.274e-175	556.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
YHH2_k127_6725948_15	381666.H16_B0376	2.353e-59	212.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria,1KBXM@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
YHH2_k127_6725948_0	1121918.ARWE01000001_gene2208	0.0	1407.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
YHH2_k127_6725948_14	580332.Slit_1173	9.838e-64	231.0	28HEC@1|root,2Z7QS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6725948_12	522306.CAP2UW1_2883	1.954e-78	272.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1NQ5K@1224|Proteobacteria,2VPHG@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
YHH2_k127_6725948_6	697282.Mettu_0562	9.096e-138	444.0	COG3437@1|root,COG3437@2|Bacteria,1QYY0@1224|Proteobacteria,1S16I@1236|Gammaproteobacteria,1XG7Y@135618|Methylococcales	135618|Methylococcales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH2_k127_6725948_2	338969.Rfer_3548	0.0	1084.0	COG0642@1|root,COG0784@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria,4AJWE@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
YHH2_k127_6725948_7	697282.Mettu_0564	3.68e-125	405.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,1RP0B@1236|Gammaproteobacteria,1XDPT@135618|Methylococcales	135618|Methylococcales	K	SMART HTH transcriptional regulator, Crp	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
YHH2_k127_6725948_11	1454004.AW11_00950	1.508e-93	314.0	COG0664@1|root,COG0664@2|Bacteria,1RAF3@1224|Proteobacteria,2VQIC@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
YHH2_k127_6725948_1	580332.Slit_1427	0.0	1406.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,44UYF@713636|Nitrosomonadales	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
YHH2_k127_6725948_10	640081.Dsui_1899	2.235e-102	340.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,2KV2Q@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
YHH2_k127_6725948_16	580332.Slit_1429	2.529e-23	100.0	2DGZJ@1|root,2ZXVD@2|Bacteria,1PA8Z@1224|Proteobacteria,2W5F6@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6725948_9	580332.Slit_1430	7.497e-118	383.0	COG1192@1|root,COG1192@2|Bacteria,1N3GB@1224|Proteobacteria,2VSGK@28216|Betaproteobacteria,44VBZ@713636|Nitrosomonadales	28216|Betaproteobacteria	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YHH2_k127_6725948_13	580332.Slit_1432	1.496e-72	248.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Abi,HTH_Crp_2,PrsW-protease,cNMP_binding
YHH2_k127_6725948_8	580332.Slit_1433	1.91e-123	402.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,44UZS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
YHH2_k127_6725948_3	666681.M301_0245	1.097e-207	656.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,2KNSE@206350|Nitrosomonadales	206350|Nitrosomonadales	I	PLD-like domain	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
YHH2_k127_6725948_5	1038869.AXAN01000063_gene4617	3.894e-170	539.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,2W5BV@28216|Betaproteobacteria,1K5NQ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH2_k127_6725948_18	1101195.Meth11DRAFT_1369	7.233e-11	63.0	COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2VSTS@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YHH2_k127_6738607_4	1163617.SCD_n01882	5.735e-104	340.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,2W0PC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17
YHH2_k127_6738607_2	292415.Tbd_1645	5.997e-141	452.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2VV9S@28216|Betaproteobacteria,1KSCV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
YHH2_k127_6738607_6	580332.Slit_1722	8.808e-75	255.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VTFS@28216|Betaproteobacteria	28216|Betaproteobacteria	P	rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH2_k127_6738607_9	1163617.SCD_n01889	1.42e-26	115.0	2E7PJ@1|root,33255@2|Bacteria,1NANJ@1224|Proteobacteria,2W4P4@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6738607_7	1485544.JQKP01000005_gene333	3.126e-55	200.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,2VHBK@28216|Betaproteobacteria,44VR5@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
YHH2_k127_6738607_3	1348657.M622_11625	8.086e-117	379.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,2VKZ3@28216|Betaproteobacteria,2KX0Z@206389|Rhodocyclales	206389|Rhodocyclales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_6738607_10	1348657.M622_11625	3.487e-09	59.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,2VKZ3@28216|Betaproteobacteria,2KX0Z@206389|Rhodocyclales	206389|Rhodocyclales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_6738607_0	580332.Slit_1474	0.0	1064.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,44VM9@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
YHH2_k127_6738607_8	1223521.BBJX01000004_gene2547	3.035e-27	112.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2VVS2@28216|Betaproteobacteria,4AFBH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
YHH2_k127_6738607_1	580332.Slit_1475	4.245e-160	508.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,44V13@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772,ko:K03815	ko00230,ko00270,ko01100,ko01110,map00230,map00270,map01100,map01110	M00034	R01402,R02297	RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YHH2_k127_6739667_0	395494.Galf_1970	6.884e-244	801.0	COG2202@1|root,COG3829@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WC2@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS_9,dCache_2
YHH2_k127_6789212_0	580332.Slit_2752	7.686e-242	750.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,44VGZ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM RNA-binding protein AU-1 Ribonuclease E G	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
YHH2_k127_6789212_2	357804.Ping_2732	4.965e-66	235.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HisKA_7TM
YHH2_k127_6789212_4	765420.OSCT_0903	1.208e-05	48.0	COG1287@1|root,COG1287@2|Bacteria,2G8R6@200795|Chloroflexi,377ZY@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6789212_1	1123487.KB892868_gene1262	8.994e-87	299.0	2ES6E@1|root,32KS5@2|Bacteria,1NXC7@1224|Proteobacteria,2W387@28216|Betaproteobacteria,2KYZI@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6804837_0	522306.CAP2UW1_2495	2.477e-267	855.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2VIEC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH2_k127_6830792_1	555778.Hneap_1226	1.546e-112	368.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,1RPJM@1236|Gammaproteobacteria,1WYYP@135613|Chromatiales	135613|Chromatiales	L	DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
YHH2_k127_6830792_0	857087.Metme_1008	1.193e-214	676.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,1RR7N@1236|Gammaproteobacteria,1XGKM@135618|Methylococcales	1236|Gammaproteobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH2_k127_6830792_2	349163.Acry_0874	7.34e-59	214.0	COG3774@1|root,COG3774@2|Bacteria	2|Bacteria	M	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Gb3_synth,Gly_transf_sug
YHH2_k127_6849750_1	1198452.Jab_2c28380	7.481e-25	118.0	2EK5A@1|root,33DVR@2|Bacteria,1NN45@1224|Proteobacteria,2VYUE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6849750_2	349521.HCH_06822	3.199e-15	90.0	2DPG8@1|root,331XY@2|Bacteria,1N9TA@1224|Proteobacteria,1SE4W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6849750_0	395494.Galf_2159	0.0	1159.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,44W7T@713636|Nitrosomonadales	28216|Betaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH2_k127_6850964_5	1331060.RLDS_11260	5.574e-18	83.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6850964_3	395961.Cyan7425_0492	1.565e-25	108.0	COG1396@1|root,COG1396@2|Bacteria,1GGP9@1117|Cyanobacteria	1117|Cyanobacteria	K	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH2_k127_6850964_2	649638.Trad_0710	5.73e-30	124.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6850964_4	713587.THITH_03440	4.47e-21	97.0	COG2442@1|root,COG2442@2|Bacteria,1N7GJ@1224|Proteobacteria,1SCUP@1236|Gammaproteobacteria,1WZKZ@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YHH2_k127_6850964_1	1123487.KB892868_gene1264	2.134e-100	331.0	COG0602@1|root,COG0602@2|Bacteria,1RA7S@1224|Proteobacteria,2VVBW@28216|Betaproteobacteria,2KXHP@206389|Rhodocyclales	206389|Rhodocyclales	O	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12
YHH2_k127_6850964_0	1123487.KB892868_gene1263	1.642e-294	915.0	COG0542@1|root,COG0542@2|Bacteria,1MWQQ@1224|Proteobacteria,2VH2V@28216|Betaproteobacteria,2KVXD@206389|Rhodocyclales	206389|Rhodocyclales	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
YHH2_k127_6858308_2	580332.Slit_0979	6.285e-142	462.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,44V32@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
YHH2_k127_6858308_3	580332.Slit_0978	3.544e-120	390.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,44VCG@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH2_k127_6858308_1	580332.Slit_0977	2.227e-193	608.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,44VD1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
YHH2_k127_6858308_13	1070319.CAGGBEG34_190118	3.76e-11	64.0	COG3550@1|root,COG3550@2|Bacteria,1PR6E@1224|Proteobacteria,2VJK8@28216|Betaproteobacteria,1K4WP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	HipA N-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
YHH2_k127_6858308_12	158500.BV97_01527	2.328e-13	72.0	2DSB8@1|root,33FCU@2|Bacteria,1NHS8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6858308_9	667632.KB890192_gene3346	3.885e-30	122.0	2FD52@1|root,34579@2|Bacteria,1P2Y8@1224|Proteobacteria,2W4EM@28216|Betaproteobacteria,1K9FM@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
YHH2_k127_6858308_6	580332.Slit_0976	9.227e-72	244.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,44VVC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	NUDIX domain	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
YHH2_k127_6858308_7	580332.Slit_0975	7.124e-50	182.0	COG2732@1|root,COG2732@2|Bacteria,1PCTM@1224|Proteobacteria,2WA4A@28216|Betaproteobacteria,44WMH@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
YHH2_k127_6858308_8	580332.Slit_0974	1.586e-41	156.0	COG4290@1|root,COG4290@2|Bacteria,1MZEZ@1224|Proteobacteria,2VTZ7@28216|Betaproteobacteria,44W1Y@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM guanine-specific ribonuclease N1 and T1	rnaSA	-	3.1.27.3	ko:K01167	-	-	-	-	ko00000,ko01000,ko03016,ko03019	-	-	-	Ribonuclease
YHH2_k127_6858308_0	580332.Slit_0973	0.0	1155.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,44V9U@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
YHH2_k127_6858308_4	580332.Slit_0972	1.845e-105	346.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,44VQ6@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
YHH2_k127_6858308_11	1121035.AUCH01000005_gene208	3.279e-27	112.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,2KXAG@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH2_k127_6858308_5	580332.Slit_0969	9.339e-94	310.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2VQAQ@28216|Betaproteobacteria,44UYV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
YHH2_k127_6858308_10	1485544.JQKP01000018_gene576	1.533e-29	123.0	COG0840@1|root,COG0840@2|Bacteria,1NKHI@1224|Proteobacteria,2WHPN@28216|Betaproteobacteria,44W48@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
YHH2_k127_6864884_4	580332.Slit_0912	8.738e-39	146.0	2E0R6@1|root,32W9H@2|Bacteria,1N4U9@1224|Proteobacteria,2VXDJ@28216|Betaproteobacteria,44WHX@713636|Nitrosomonadales	28216|Betaproteobacteria	S	NifZ domain	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
YHH2_k127_6864884_3	580332.Slit_0911	1.771e-43	168.0	2EBC7@1|root,33D8I@2|Bacteria,1NJS3@1224|Proteobacteria,2VYPY@28216|Betaproteobacteria,44WH0@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6864884_1	580332.Slit_0910	9.616e-54	195.0	COG3411@1|root,COG3411@2|Bacteria,1Q5IQ@1224|Proteobacteria,2WCSS@28216|Betaproteobacteria,44WM1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6864884_2	580332.Slit_0909	3.723e-53	188.0	COG1143@1|root,COG1143@2|Bacteria,1N1SG@1224|Proteobacteria,2VT6Z@28216|Betaproteobacteria,44WJ1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S double cluster binding domain	fdxB	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
YHH2_k127_6864884_6	580332.Slit_0908	1.066e-27	116.0	2DQ5Y@1|root,334WI@2|Bacteria,1QWGA@1224|Proteobacteria,2VWW1@28216|Betaproteobacteria,44WJN@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Rop-like	-	-	-	-	-	-	-	-	-	-	-	-	Rop-like
YHH2_k127_6864884_0	580332.Slit_0907	2.16e-81	272.0	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,2VQYS@28216|Betaproteobacteria,44WBZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function, DUF269	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
YHH2_k127_6864884_5	580332.Slit_0906	5.975e-37	141.0	COG3086@1|root,COG3086@2|Bacteria,1NMXY@1224|Proteobacteria,2W88E@28216|Betaproteobacteria,44WJ3@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Positive regulator of sigma(E), RseC/MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
YHH2_k127_6883378_17	580332.Slit_1633	7.289e-80	268.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,44VSM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YHH2_k127_6883378_19	580332.Slit_1632	1.456e-76	261.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,44VUY@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	ratA	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
YHH2_k127_6883378_25	580332.Slit_1631	7.497e-49	178.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,44VZ5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
YHH2_k127_6883378_8	580332.Slit_1630	3.372e-159	505.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,2VHB2@28216|Betaproteobacteria,44VHP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DNA polymerase alpha chain like domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
YHH2_k127_6883378_12	580332.Slit_1629	1.365e-120	388.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,44VHQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
YHH2_k127_6883378_13	580332.Slit_1627	4.655e-120	387.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria,44VNY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
YHH2_k127_6883378_3	580332.Slit_1626	8.144e-253	781.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria,44V3N@713636|Nitrosomonadales	28216|Betaproteobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH2_k127_6883378_27	321327.CYA_1312	1.363e-35	139.0	COG1708@1|root,COG1708@2|Bacteria,1GB1D@1117|Cyanobacteria	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH2_k127_6883378_9	580332.Slit_1625	1.42e-141	454.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,44VJ2@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
YHH2_k127_6883378_16	580332.Slit_1624	1.292e-96	323.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,44VTG@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Segregation and condensation complex subunit ScpB	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
YHH2_k127_6883378_6	323848.Nmul_A2184	4.695e-192	606.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VHG5@28216|Betaproteobacteria,371Q8@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
YHH2_k127_6883378_29	765911.Thivi_1551	2.815e-31	125.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	ko:K07733	-	-	-	-	ko00000,ko03000	-	-	-	Phage_AlpA
YHH2_k127_6883378_24	1267534.KB906755_gene3949	9.007e-52	187.0	2E48J@1|root,32Z4E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
YHH2_k127_6883378_7	1267534.KB906755_gene3950	4.145e-177	561.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_5,Phage_integrase
YHH2_k127_6883378_33	1454004.AW11_01166	2.862e-20	97.0	2DQSG@1|root,338DT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6883378_28	323848.Nmul_A2160	1.959e-31	125.0	COG3655@1|root,COG3655@2|Bacteria,1NA11@1224|Proteobacteria,2VWT4@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
YHH2_k127_6883378_35	404380.Gbem_1748	6.949e-09	61.0	2CHP3@1|root,33CM7@2|Bacteria,1NHT2@1224|Proteobacteria,42XX2@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6883378_18	85643.Tmz1t_0308	1.075e-78	271.0	2DDN5@1|root,2ZIMY@2|Bacteria,1PAE7@1224|Proteobacteria,2W54H@28216|Betaproteobacteria,2KZMX@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6883378_21	580332.Slit_1742	2.497e-75	257.0	COG1127@1|root,COG1127@2|Bacteria,1P91Q@1224|Proteobacteria	1224|Proteobacteria	Q	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6883378_14	580332.Slit_1741	8.799e-118	388.0	COG1463@1|root,COG1463@2|Bacteria,1PP5N@1224|Proteobacteria,2VV89@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
YHH2_k127_6883378_20	580332.Slit_1740	1.252e-75	263.0	COG0457@1|root,COG0457@2|Bacteria,1P9X0@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6883378_5	580332.Slit_1739	5.146e-201	642.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MWHK@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate cyclase	cyaG2	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,NTP_transf_9
YHH2_k127_6883378_11	580332.Slit_1738	6.79e-123	398.0	COG0767@1|root,COG0767@2|Bacteria,1N2HV@1224|Proteobacteria	1224|Proteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YHH2_k127_6883378_2	580332.Slit_1737	0.0	1262.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,44V7H@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
YHH2_k127_6883378_15	580332.Slit_1736	1.921e-100	328.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,44VQU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
YHH2_k127_6883378_30	580332.Slit_1735	3.805e-30	119.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria,44W2J@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
YHH2_k127_6883378_22	580332.Slit_1734	5.351e-63	217.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,44VWN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
YHH2_k127_6883378_4	580332.Slit_1733	2.534e-210	654.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,44VDW@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YHH2_k127_6883378_0	580332.Slit_1731	0.0	1315.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,44V1R@713636|Nitrosomonadales	28216|Betaproteobacteria	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
YHH2_k127_6883378_26	375286.mma_1493	7.713e-47	169.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,47411@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH2_k127_6883378_23	580332.Slit_1729	1.02e-59	208.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,44VW7@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
YHH2_k127_6883378_1	580332.Slit_1663	0.0	1269.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,44VJV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
YHH2_k127_6883378_34	62928.azo1372	3.995e-09	61.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_6883378_10	395494.Galf_1134	2.219e-141	452.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,44VG0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Metallopeptidase family M24	map	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH2_k127_6920569_2	580332.Slit_0471	3.285e-98	326.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,44VFK@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Phosphate acyltransferases	nlaB	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH2_k127_6920569_3	580332.Slit_0470	3.128e-91	303.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2VQ49@28216|Betaproteobacteria,44VFT@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Polynucleotide kinase 3 phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_like,PNK3P
YHH2_k127_6920569_0	580332.Slit_0469	0.0	1153.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,44VBX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
YHH2_k127_6920569_1	580332.Slit_0468	9.378e-193	601.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,44VDK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
YHH2_k127_6920569_6	1366050.N234_16255	1.984e-19	91.0	2D3E2@1|root,32TET@2|Bacteria,1N2S5@1224|Proteobacteria,2VYYV@28216|Betaproteobacteria,1KAT7@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_6920569_5	713587.THITH_00195	1.13e-31	128.0	COG1569@1|root,COG1569@2|Bacteria,1MYFF@1224|Proteobacteria,1S5ZX@1236|Gammaproteobacteria,1X1WJ@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH2_k127_6920569_4	580332.Slit_0467	5.233e-36	141.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,2VWG2@28216|Betaproteobacteria,44W37@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Excinuclease ABC C subunit domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH2_k127_6929288_11	580332.Slit_1644	2.213e-27	111.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,44V27@713636|Nitrosomonadales	28216|Betaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
YHH2_k127_6929288_0	580332.Slit_1643	0.0	1094.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,44V63@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YHH2_k127_6929288_8	580332.Slit_1642	3.089e-64	224.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria,44VX8@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
YHH2_k127_6929288_2	580332.Slit_1641	1.426e-158	506.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,44V3V@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
YHH2_k127_6929288_6	580332.Slit_1640	1.147e-78	269.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,44VTF@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
YHH2_k127_6929288_3	1163617.SCD_n01623	3.207e-132	424.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
YHH2_k127_6929288_1	580332.Slit_1638	9.72e-208	649.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria,44VEA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
YHH2_k127_6929288_4	580332.Slit_1637	3.517e-99	331.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,44VRD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH2_k127_6929288_7	580332.Slit_1636	1.852e-70	242.0	COG5615@1|root,COG5615@2|Bacteria,1N3BK@1224|Proteobacteria,2VQHM@28216|Betaproteobacteria,44WI1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
YHH2_k127_6929288_5	580332.Slit_1634	3.076e-88	294.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2VKRT@28216|Betaproteobacteria,44VRJ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
YHH2_k127_6929288_10	580332.Slit_0386	1.195e-31	126.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_6929288_9	580332.Slit_0385	1.313e-34	136.0	2AQRK@1|root,31FZD@2|Bacteria,1P8IP@1224|Proteobacteria,2W5A4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
YHH2_k127_6982410_0	580332.Slit_1484	2.36e-159	506.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,44UZ4@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
YHH2_k127_6982410_3	580332.Slit_1483	2.303e-60	211.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,44VW4@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
YHH2_k127_6982410_1	580332.Slit_1482	4.383e-145	473.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,44V5A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
YHH2_k127_6982410_2	228410.NE1320	2.85e-103	339.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,371RP@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
YHH2_k127_7021378_1	232721.Ajs_2200	2.199e-07	52.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,2VKAK@28216|Betaproteobacteria,4AJKJ@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3
YHH2_k127_7021378_0	358220.C380_06710	7.231e-57	211.0	COG4585@1|root,COG4585@2|Bacteria,1R8DN@1224|Proteobacteria,2VPJ9@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
YHH2_k127_7070169_1	713586.KB900536_gene1944	3.056e-09	60.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH2_k127_7070169_0	580332.Slit_1711	8.639e-307	940.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,44WAX@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YHH2_k127_7079224_7	358220.C380_06705	7.288e-32	127.0	COG2197@1|root,COG2197@2|Bacteria,1RGXD@1224|Proteobacteria,2WEGP@28216|Betaproteobacteria,4AJP9@80864|Comamonadaceae	28216|Betaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_7079224_1	580332.Slit_0097	0.0	1004.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,44VKU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ABC transporter related	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
YHH2_k127_7079224_3	395494.Galf_0106	3.692e-109	359.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2VQ46@28216|Betaproteobacteria,44UYG@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
YHH2_k127_7079224_2	118005.AWNK01000001_gene2091	1.59e-211	681.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_9
YHH2_k127_7079224_4	314345.SPV1_13397	2.576e-88	311.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5,PAS_4,PAS_9,Response_reg
YHH2_k127_7079224_6	1163617.SCD_n00685	1.66e-43	165.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
YHH2_k127_7079224_5	686340.Metal_3381	1.477e-62	218.0	COG1943@1|root,COG1943@2|Bacteria,1MZZT@1224|Proteobacteria,1S9JG@1236|Gammaproteobacteria,1XGEA@135618|Methylococcales	135618|Methylococcales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH2_k127_7079224_0	697282.Mettu_4224	0.0	1307.0	COG1196@1|root,COG1352@1|root,COG2201@1|root,COG1196@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,1T2RH@1236|Gammaproteobacteria,1XE6G@135618|Methylococcales	135618|Methylococcales	NT	PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
YHH2_k127_7079811_7	1502852.FG94_00056	8.283e-13	71.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,472ET@75682|Oxalobacteraceae	28216|Betaproteobacteria	CH	Squalene epoxidase	ubiF	-	-	ko:K03184,ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R06146,R08773,R08775	RC01254,RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
YHH2_k127_7079811_1	580332.Slit_0252	5.349e-299	930.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
YHH2_k127_7079811_0	580332.Slit_0253	0.0	1515.0	COG0457@1|root,COG1305@1|root,COG3391@1|root,COG4733@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,1R42S@1224|Proteobacteria	1224|Proteobacteria	E	fibronectin type III domain protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	-
YHH2_k127_7079811_6	580332.Slit_0254	7.972e-36	139.0	COG1729@1|root,COG1729@2|Bacteria,1P69R@1224|Proteobacteria,2W622@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7079811_3	580332.Slit_0255	5.085e-235	731.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,44VIX@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
YHH2_k127_7079811_4	580332.Slit_0256	7.11e-213	665.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,44VAN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH2_k127_7079811_5	580332.Slit_2147	7.271e-110	361.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,2VI8F@28216|Betaproteobacteria	28216|Betaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH2_k127_7079811_9	1120999.JONM01000021_gene108	2.219e-05	50.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,2KSSW@206351|Neisseriales	206351|Neisseriales	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
YHH2_k127_7079811_2	1485544.JQKP01000002_gene1496	5.517e-281	868.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,44VKV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YHH2_k127_7080980_0	580332.Slit_0446	3.55e-239	747.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,2VHAA@28216|Betaproteobacteria,44VHN@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Malate:quinone oxidoreductase (Mqo)	mqo	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
YHH2_k127_7080980_18	261292.Nit79A3_1685	2.362e-30	123.0	COG3514@1|root,COG3514@2|Bacteria,1NAV1@1224|Proteobacteria,2W4YE@28216|Betaproteobacteria,374JI@32003|Nitrosomonadales	28216|Betaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
YHH2_k127_7080980_17	870187.Thini_0083	5.38e-32	126.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,1SESI@1236|Gammaproteobacteria,463D1@72273|Thiotrichales	72273|Thiotrichales	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_7080980_2	580332.Slit_2960	5.803e-198	619.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,44V1G@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
YHH2_k127_7080980_4	580332.Slit_2962	1.922e-145	465.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria,44V8U@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YHH2_k127_7080980_8	580332.Slit_2963	3.634e-114	381.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,2VSUT@28216|Betaproteobacteria,44W8F@713636|Nitrosomonadales	28216|Betaproteobacteria	M	LppC putative lipoprotein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
YHH2_k127_7080980_14	580332.Slit_2964	8.354e-47	170.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,44VYK@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
YHH2_k127_7080980_9	580332.Slit_2965	7.275e-96	317.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,44VMZ@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
YHH2_k127_7080980_13	580332.Slit_2966	5.13e-52	189.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria,44VX2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
YHH2_k127_7080980_10	580332.Slit_2967	3.616e-85	285.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,2VR6S@28216|Betaproteobacteria,44VQT@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	aut	-	2.7.7.70	ko:K21345	ko00540,ko01100,map00540,map01100	M00064	R05644	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YHH2_k127_7080980_12	580332.Slit_2968	1.229e-60	213.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,44VXY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
YHH2_k127_7080980_5	580332.Slit_2969	5.575e-141	450.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,44VA7@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
YHH2_k127_7080980_7	75379.Tint_2222	8.458e-117	381.0	COG0322@1|root,COG0322@2|Bacteria,1N84M@1224|Proteobacteria	1224|Proteobacteria	L	excinuclease ABC activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7080980_19	395494.Galf_2899	3.528e-29	119.0	COG3905@1|root,COG3905@2|Bacteria,1N7SQ@1224|Proteobacteria,2VVRJ@28216|Betaproteobacteria,44WJZ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7080980_16	1120999.JONM01000004_gene3562	2.947e-35	137.0	COG3668@1|root,COG3668@2|Bacteria,1PSEU@1224|Proteobacteria,2WATI@28216|Betaproteobacteria,2KTQW@206351|Neisseriales	206351|Neisseriales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_7080980_11	580332.Slit_2972	2.977e-65	224.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,2VSKS@28216|Betaproteobacteria,44VY9@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM alkylphosphonate utilization operon protein PhnA	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
YHH2_k127_7080980_20	580332.Slit_2973	5.336e-23	100.0	2DR87@1|root,33AMS@2|Bacteria,1NJ06@1224|Proteobacteria,2VXG7@28216|Betaproteobacteria,44W2I@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7080980_6	580332.Slit_2927	9.75e-119	388.0	COG3511@1|root,COG3511@2|Bacteria,1RCY1@1224|Proteobacteria,2WEZW@28216|Betaproteobacteria,44WCM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
YHH2_k127_7080980_3	580332.Slit_0318	7.892e-159	512.0	COG4692@1|root,COG4692@2|Bacteria,1Q1EG@1224|Proteobacteria,2VMXN@28216|Betaproteobacteria,44VCC@713636|Nitrosomonadales	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
YHH2_k127_7080980_15	1485544.JQKP01000011_gene761	5.642e-37	146.0	2ETRW@1|root,33M9C@2|Bacteria,1NEBE@1224|Proteobacteria,2VXIY@28216|Betaproteobacteria,44W11@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7080980_1	580332.Slit_0320	1.351e-222	695.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VIPI@28216|Betaproteobacteria,44WDF@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	proP	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH2_k127_7088233_10	580332.Slit_2078	2.71e-10	60.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria,44V5Z@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_7088233_1	580332.Slit_2077	5.297e-216	679.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria,44UZP@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_7088233_2	580332.Slit_2076	1.074e-192	607.0	COG4394@1|root,COG4394@2|Bacteria,1MYVF@1224|Proteobacteria,2VHIB@28216|Betaproteobacteria,44V84@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2331
YHH2_k127_7088233_7	580332.Slit_2075	3.014e-114	369.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VH4A@28216|Betaproteobacteria,44VJK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YHH2_k127_7088233_4	580332.Slit_2074	2.16e-160	509.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,2VKZK@28216|Betaproteobacteria,44V5J@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
YHH2_k127_7088233_0	580332.Slit_2073	0.0	1037.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44W4Z@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	General secretory system II protein E domain protein	gspE1	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH2_k127_7088233_6	1348657.M622_15540	1.477e-130	429.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2VMN6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HipA domain protein	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
YHH2_k127_7088233_9	232721.Ajs_3589	1.815e-15	80.0	COG1396@1|root,COG1396@2|Bacteria,1RM6S@1224|Proteobacteria,2VUX0@28216|Betaproteobacteria,4AIF4@80864|Comamonadaceae	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH2_k127_7088233_3	580332.Slit_2071	1.073e-163	532.0	COG2114@1|root,COG2703@1|root,COG2114@2|Bacteria,COG2703@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,44WAE@713636|Nitrosomonadales	28216|Betaproteobacteria	PT	SMART adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
YHH2_k127_7088233_8	1163617.SCD_n01022	1.445e-71	248.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphoglycolate phosphatase	gph	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH2_k127_7088233_5	580332.Slit_2069	4.061e-139	443.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,44UZN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
YHH2_k127_7118826_1	580332.Slit_1864	8.222e-214	674.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,44VFA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM efflux transporter, RND family, MFP subunit	cusB	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	CusF_Ec,HlyD_D23
YHH2_k127_7118826_0	580332.Slit_1865	0.0	1774.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,44VI6@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM heavy metal efflux pump, CzcA family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
YHH2_k127_7118826_2	580332.Slit_1866	7.396e-22	97.0	COG5569@1|root,COG5569@2|Bacteria,1NGSZ@1224|Proteobacteria,2VXT4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Copper binding periplasmic protein CusF	-	-	-	-	-	-	-	-	-	-	-	-	CusF_Ec
YHH2_k127_7138940_0	1348657.M622_03090	0.0	1168.0	COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,2VMKD@28216|Betaproteobacteria	28216|Betaproteobacteria	V	type II restriction enzyme, methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
YHH2_k127_7138940_1	194439.CT1466	2.034e-87	299.0	COG4916@1|root,COG4916@2|Bacteria	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat,SIR2_2,TIR_2
YHH2_k127_7138940_8	457398.HMPREF0326_01464	0.0003156	48.0	COG3905@1|root,COG3905@2|Bacteria,1NHN3@1224|Proteobacteria,431E7@68525|delta/epsilon subdivisions,2WX15@28221|Deltaproteobacteria,2ME0S@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
YHH2_k127_7138940_5	215803.DB30_7367	1.75e-20	94.0	2APNA@1|root,31ERS@2|Bacteria,1QA23@1224|Proteobacteria,434S9@68525|delta/epsilon subdivisions,2WZ3B@28221|Deltaproteobacteria,2Z18I@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7138940_7	743299.Acife_0954	4.277e-08	57.0	COG4453@1|root,COG4453@2|Bacteria,1N71W@1224|Proteobacteria,1T99U@1236|Gammaproteobacteria,2NE2J@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
YHH2_k127_7138940_3	338969.Rfer_0415	5.974e-52	188.0	COG1495@1|root,COG1495@2|Bacteria,1N2C1@1224|Proteobacteria,2VTN0@28216|Betaproteobacteria,4AICZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Disulfide bond formation protein DsbB	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
YHH2_k127_7138940_2	338969.Rfer_0414	2.022e-77	268.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria,2VQH7@28216|Betaproteobacteria,4AGU8@80864|Comamonadaceae	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YHH2_k127_7138940_6	945543.VIBR0546_13775	5.343e-13	73.0	2EGVV@1|root,33AN3@2|Bacteria,1NJ5K@1224|Proteobacteria,1S9PZ@1236|Gammaproteobacteria,1XZ64@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7138940_4	305700.B447_10063	1.568e-40	152.0	COG5649@1|root,COG5649@2|Bacteria,1ND08@1224|Proteobacteria,2VV2M@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
YHH2_k127_7225015_3	228410.NE2113	9.043e-17	86.0	COG4113@1|root,COG4113@2|Bacteria,1RIR6@1224|Proteobacteria,2VSUI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_7225015_0	1165096.ARWF01000001_gene557	5.769e-303	937.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,2VHZY@28216|Betaproteobacteria,2KKTK@206350|Nitrosomonadales	206350|Nitrosomonadales	O	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
YHH2_k127_7225015_2	1095769.CAHF01000025_gene622	2.497e-51	195.0	2E8C6@1|root,332QU@2|Bacteria,1NBRE@1224|Proteobacteria,2VVRG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7225015_1	580332.Slit_1227	1.209e-65	237.0	COG3153@1|root,COG3153@2|Bacteria,1QUTM@1224|Proteobacteria,2WHYE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
YHH2_k127_7283371_5	580332.Slit_2065	9.306e-192	604.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,44UYW@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Chorismate mutase type II	pheA	-	4.2.1.51,4.2.1.91,5.4.99.5	ko:K01713,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
YHH2_k127_7283371_4	580332.Slit_2067	5.551e-196	614.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,44VKB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
YHH2_k127_7283371_6	324925.Ppha_1125	5.159e-178	561.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YHH2_k127_7283371_7	324925.Ppha_1124	1.035e-161	517.0	COG2865@1|root,COG2865@2|Bacteria	2|Bacteria	-	-	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_24
YHH2_k127_7283371_0	580332.Slit_2068	0.0	1560.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,44VGS@713636|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH2_k127_7283371_10	395494.Galf_0886	6.756e-137	444.0	COG2253@1|root,COG2253@2|Bacteria,1QNXP@1224|Proteobacteria,2VNUU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH2_k127_7283371_13	395494.Galf_0885	1.553e-86	290.0	28KYY@1|root,2ZAEA@2|Bacteria,1RB7S@1224|Proteobacteria,2VJW1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7283371_14	686340.Metal_2049	3.326e-72	246.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,1RSJY@1236|Gammaproteobacteria,1XFE6@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_7283371_22	713587.THITH_00265	1.44e-16	81.0	2EGSU@1|root,33AIY@2|Bacteria,1NKKM@1224|Proteobacteria,1STDS@1236|Gammaproteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7283371_21	1167006.UWK_00700	6.49e-21	94.0	2DR98@1|root,33ARN@2|Bacteria,1NHFU@1224|Proteobacteria,42X3T@68525|delta/epsilon subdivisions,2WSSX@28221|Deltaproteobacteria,2MMBR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
YHH2_k127_7283371_16	1167006.UWK_00701	3.713e-36	140.0	COG3668@1|root,COG3668@2|Bacteria,1N8DJ@1224|Proteobacteria,42VZU@68525|delta/epsilon subdivisions,2WRB9@28221|Deltaproteobacteria,2MM4U@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7283371_20	1123053.AUDG01000121_gene824	1.906e-24	105.0	2DC1I@1|root,2ZCFR@2|Bacteria,1RBUV@1224|Proteobacteria,1S24Y@1236|Gammaproteobacteria,1X1ZY@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7283371_19	1123053.AUDG01000121_gene824	3.515e-28	115.0	2DC1I@1|root,2ZCFR@2|Bacteria,1RBUV@1224|Proteobacteria,1S24Y@1236|Gammaproteobacteria,1X1ZY@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7283371_1	686340.Metal_0607	0.0	1289.0	COG1111@1|root,COG4889@1|root,COG1111@2|Bacteria,COG4889@2|Bacteria,1QZFK@1224|Proteobacteria	1224|Proteobacteria	L	type iii restriction	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,Mrr_cat_2,N6_Mtase,ResIII
YHH2_k127_7283371_15	1415779.JOMH01000001_gene1313	5.019e-42	156.0	COG2337@1|root,COG2337@2|Bacteria,1MZAV@1224|Proteobacteria,1S7ZM@1236|Gammaproteobacteria,1X7RE@135614|Xanthomonadales	135614|Xanthomonadales	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH2_k127_7283371_18	1485544.JQKP01000003_gene143	3.737e-30	120.0	2C78Q@1|root,331C6@2|Bacteria,1N873@1224|Proteobacteria,2VY62@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein  of unknown function (DUF3018)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3018
YHH2_k127_7283371_12	580332.Slit_1055	6.291e-91	301.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,2VRHU@28216|Betaproteobacteria,44WDJ@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
YHH2_k127_7283371_2	580332.Slit_1054	0.0	1158.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKYE@28216|Betaproteobacteria,44W7M@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
YHH2_k127_7283371_8	580332.Slit_1053	1.152e-149	475.0	COG0426@1|root,COG0426@2|Bacteria,1R4UD@1224|Proteobacteria,2VJKW@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH2_k127_7283371_9	580332.Slit_1051	3.054e-137	439.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,44VID@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
YHH2_k127_7283371_17	395494.Galf_2153	7.284e-34	134.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria,44W20@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
YHH2_k127_7283371_3	580332.Slit_1049	1.575e-272	847.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,44VHC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
YHH2_k127_7283371_11	395494.Galf_2155	6.786e-134	431.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria,44VMV@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
YHH2_k127_7507984_0	1504672.669787404	2.311e-228	711.0	COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,2VMKD@28216|Betaproteobacteria,4ACZU@80864|Comamonadaceae	28216|Betaproteobacteria	V	type II restriction enzyme, methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
YHH2_k127_7507984_5	1485544.JQKP01000012_gene2127	2.065e-29	120.0	COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,44V1J@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Oxidoreductase FAD-binding domain protein	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
YHH2_k127_7507984_3	1485544.JQKP01000002_gene1483	2.503e-86	291.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,44VPV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Ribosomal RNA adenine dimethylase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
YHH2_k127_7507984_1	580332.Slit_2913	1.229e-198	626.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,44VIB@713636|Nitrosomonadales	28216|Betaproteobacteria	MU	TIGRFAM type I secretion outer membrane protein, TolC family	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
YHH2_k127_7507984_4	580332.Slit_2823	1.104e-44	163.0	COG1872@1|root,COG1872@2|Bacteria,1PW6G@1224|Proteobacteria,2WBRH@28216|Betaproteobacteria,44WKF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
YHH2_k127_7507984_2	580332.Slit_2824	7.441e-111	363.0	COG1187@1|root,COG1187@2|Bacteria,1PYTZ@1224|Proteobacteria,2VNU1@28216|Betaproteobacteria,44VFC@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	S4
YHH2_k127_7514373_0	395494.Galf_0561	7.995e-139	442.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,44V4Z@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YHH2_k127_7514373_2	1485544.JQKP01000001_gene1112	7.572e-48	173.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2VU1C@28216|Betaproteobacteria,44VXD@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
YHH2_k127_7514373_1	395494.Galf_0559	2.89e-105	345.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2VHS6@28216|Betaproteobacteria,44V4P@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YHH2_k127_7514373_3	395494.Galf_0558	8.812e-10	59.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2VJ3V@28216|Betaproteobacteria,44VDP@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
YHH2_k127_7591976_0	765913.ThidrDRAFT_0597	0.0	1509.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1X2PM@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4
YHH2_k127_7591976_2	1126627.BAWE01000002_gene419	3.856e-26	114.0	2BRF4@1|root,32KE0@2|Bacteria,1Q610@1224|Proteobacteria,2TU9G@28211|Alphaproteobacteria,3JUSE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7591976_1	864073.HFRIS_006043	3.99e-53	188.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VIGR@28216|Betaproteobacteria,4731X@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit	fdsB	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Complex1_51K,NADH_4Fe-4S
YHH2_k127_7594934_0	926569.ANT_30160	8.087e-129	415.0	COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_7594934_1	747365.Thena_0761	6.867e-91	310.0	COG2801@1|root,COG2801@2|Bacteria,1UINX@1239|Firmicutes,24BC3@186801|Clostridia	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH2_k127_7628003_1	1485544.JQKP01000005_gene337	0.0	1482.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,44VE5@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
YHH2_k127_7628003_3	580332.Slit_1056	3.296e-229	712.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2VH9Q@28216|Betaproteobacteria,44V9F@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
YHH2_k127_7628003_0	580332.Slit_1057	0.0	2041.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,44V81@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM Carbamoyl-phosphate synthase L chain ATP-binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YHH2_k127_7628003_6	580332.Slit_1058	5.982e-85	283.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,44VQE@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
YHH2_k127_7628003_8	580332.Slit_1059	4.68e-49	177.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,2VVP0@28216|Betaproteobacteria,44VYX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	CRS1_YhbY	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
YHH2_k127_7628003_5	580332.Slit_1060	2.607e-116	376.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,44UZM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
YHH2_k127_7628003_2	1485544.JQKP01000008_gene1767	0.0	1086.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,44VHK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YHH2_k127_7628003_4	580332.Slit_1062	1.127e-129	419.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,44V46@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
YHH2_k127_7628003_7	395494.Galf_1350	5.717e-52	188.0	COG2944@1|root,COG2944@2|Bacteria,1NM4T@1224|Proteobacteria,2VYE7@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Phage protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3653,HTH_3,HTH_31
YHH2_k127_7628003_9	1331060.RLDS_11260	1.201e-18	85.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7688023_4	580332.Slit_2573	1.84e-117	381.0	COG2834@1|root,COG2834@2|Bacteria,1RE9C@1224|Proteobacteria,2VSUX@28216|Betaproteobacteria,44W9W@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
YHH2_k127_7688023_7	2340.JV46_24970	1.842e-95	325.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RQGQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
YHH2_k127_7688023_11	521045.Kole_0620	1.933e-27	117.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	AAT,AMPK1_CBM,CBAH
YHH2_k127_7688023_9	477641.MODMU_4071	2.928e-72	252.0	COG2220@1|root,COG2220@2|Bacteria,2GMTR@201174|Actinobacteria,4EUVJ@85013|Frankiales	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
YHH2_k127_7688023_5	697282.Mettu_1629	1.445e-115	377.0	COG1073@1|root,COG1073@2|Bacteria,1RBYZ@1224|Proteobacteria,1SDYB@1236|Gammaproteobacteria,1XFXM@135618|Methylococcales	135618|Methylococcales	S	Lipid-droplet associated hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7688023_2	580332.Slit_2571	2.776e-156	503.0	2BS95@1|root,32MAT@2|Bacteria,1RHA2@1224|Proteobacteria,2VYR6@28216|Betaproteobacteria,44WC5@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7688023_12	62928.azo1372	9.989e-08	53.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_7688023_3	1485544.JQKP01000001_gene1043	1.466e-137	445.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VRIK@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
YHH2_k127_7688023_6	1485544.JQKP01000001_gene1044	2.274e-115	376.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2VKFT@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
YHH2_k127_7688023_0	580332.Slit_0903	1.232e-280	866.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,2VJ11@28216|Betaproteobacteria,44WB6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifE	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
YHH2_k127_7688023_1	580332.Slit_0904	3.21e-247	770.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,2VJNA@28216|Betaproteobacteria,44W97@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifN	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
YHH2_k127_7688023_10	580332.Slit_0905	1.171e-60	214.0	COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,2VUUQ@28216|Betaproteobacteria,44WF9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
YHH2_k127_7726139_0	1396418.BATQ01000139_gene3245	4.965e-69	238.0	COG2764@1|root,COG2764@2|Bacteria,46W8S@74201|Verrucomicrobia,2IWEY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
YHH2_k127_7726139_2	1094980.Mpsy_1901	1.356e-38	149.0	COG3832@1|root,arCOG05261@2157|Archaea,2Y3Q0@28890|Euryarchaeota	28890|Euryarchaeota	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YHH2_k127_7726139_1	375286.mma_1843	5.053e-57	203.0	COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,2VRWE@28216|Betaproteobacteria,4749B@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
YHH2_k127_7726142_2	395494.Galf_1350	1.714e-53	192.0	COG2944@1|root,COG2944@2|Bacteria,1NM4T@1224|Proteobacteria,2VYE7@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Phage protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3653,HTH_3,HTH_31
YHH2_k127_7726142_1	580332.Slit_1537	2.43e-135	436.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,44V7Z@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TatD related DNase	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YHH2_k127_7726142_0	580332.Slit_1536	2.973e-162	513.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,44VBK@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
YHH2_k127_7767224_0	580332.Slit_2564	5.955e-284	877.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,2VMAN@28216|Betaproteobacteria,44WCY@713636|Nitrosomonadales	28216|Betaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	hyfB	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
YHH2_k127_7767224_4	83406.HDN1F_35200	1.603e-20	94.0	COG3668@1|root,COG3668@2|Bacteria,1N9C2@1224|Proteobacteria,1SB1Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_7767224_5	1038858.AXBA01000028_gene1030	1.809e-09	63.0	COG3905@1|root,COG3905@2|Bacteria,1N8CE@1224|Proteobacteria,2UF9S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
YHH2_k127_7767224_1	1538295.JY96_05455	1.074e-201	645.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,1KKDF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	acetolactate synthase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YHH2_k127_7767224_2	398767.Glov_1113	6.665e-104	347.0	COG0372@1|root,COG0372@2|Bacteria,1R5N1@1224|Proteobacteria	1224|Proteobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
YHH2_k127_7767224_3	857087.Metme_1119	3.127e-95	318.0	COG0372@1|root,COG0372@2|Bacteria,1RCFK@1224|Proteobacteria,1S2C0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
YHH2_k127_7789610_1	375286.mma_0010	2.482e-46	175.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria,476AX@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	TIGRFAM filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
YHH2_k127_7789610_0	323848.Nmul_A1796	1.017e-246	807.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2VJB8@28216|Betaproteobacteria,372U8@32003|Nitrosomonadales	28216|Betaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
YHH2_k127_7789610_2	62928.azo1372	0.0002544	44.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_7791350_4	580332.Slit_2169	7.931e-82	277.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,2WEFV@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	3.1.2.20	ko:K01073	-	-	-	-	ko00000,ko01000	-	-	-	Lipase_GDSL_2
YHH2_k127_7791350_1	580332.Slit_1671	1.031e-237	743.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,44V1J@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Oxidoreductase FAD-binding domain protein	ascD	-	1.17.1.1	ko:K00523,ko:K18248	ko00520,ko00627,ko01120,map00520,map00627,map01120	M00637	R00823,R00825,R03391,R03392	RC00192,RC00230	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
YHH2_k127_7791350_3	580332.Slit_0122	1.423e-131	426.0	COG0369@1|root,COG0369@2|Bacteria,1NCKQ@1224|Proteobacteria,2VIZE@28216|Betaproteobacteria	28216|Betaproteobacteria	C	benzoyl-CoA oxygenase	boxA	-	1.14.13.208,1.18.1.2,1.19.1.1	ko:K00528,ko:K02641,ko:K15511	ko00195,ko00362,ko01100,map00195,map00362,map01100	-	R09555,R10159	RC01739	ko00000,ko00001,ko00194,ko01000	-	-	-	FAD_binding_6,Fer4,NAD_binding_1
YHH2_k127_7791350_10	706587.Desti_5213	3.134e-05	48.0	COG1598@1|root,COG1598@2|Bacteria,1NDHG@1224|Proteobacteria,432RS@68525|delta/epsilon subdivisions,2WXV3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7791350_11	62928.azo2955	0.0001109	47.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KUGU@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
YHH2_k127_7791350_2	76114.p2A75	5.068e-212	667.0	COG3177@1|root,COG3177@2|Bacteria,1MXWY@1224|Proteobacteria,2VMBH@28216|Betaproteobacteria	28216|Betaproteobacteria	K	filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH2_k127_7791350_0	580332.Slit_2915	0.0	1198.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,44VN2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
YHH2_k127_7791350_9	1485544.JQKP01000002_gene1484	2.999e-10	63.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,44VN2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
YHH2_k127_7791350_6	637390.AFOH01000041_gene2301	8.978e-30	122.0	COG2944@1|root,COG2944@2|Bacteria,1RJY8@1224|Proteobacteria,1SPEB@1236|Gammaproteobacteria,2NDUT@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	ko:K13655	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	MqsA_antitoxin
YHH2_k127_7791350_7	522306.CAP2UW1_0225	2.364e-13	70.0	2D16E@1|root,331SX@2|Bacteria,1NAS7@1224|Proteobacteria,2VXGE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Motility quorum-sensing regulator, toxin of MqsA	-	-	-	ko:K13651	-	-	-	-	ko00000,ko02048	-	-	-	MqsR_toxin
YHH2_k127_7791811_1	1217656.F964_02338	4.488e-13	85.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,3NM1J@468|Moraxellaceae	1236|Gammaproteobacteria	U	Large exoproteins involved in heme utilization or adhesion	cupB5	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
YHH2_k127_7791811_0	426117.M446_5785	6.888e-181	635.0	COG3210@1|root,COG3291@1|root,COG5492@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,1MXIP@1224|Proteobacteria,2TTVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Glug,Haemagg_act
YHH2_k127_781817_7	608538.HTH_0808	4.382e-06	59.0	COG0644@1|root,COG0644@2|Bacteria,2G46Q@200783|Aquificae	200783|Aquificae	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
YHH2_k127_781817_0	1499967.BAYZ01000164_gene6661	2.803e-184	611.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,2NS5N@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,dCache_1
YHH2_k127_781817_4	555779.Dthio_PD0609	4.877e-95	320.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2WIYG@28221|Deltaproteobacteria,2M81D@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
YHH2_k127_781817_2	580332.Slit_0726	2.652e-144	470.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,44WE9@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
YHH2_k127_781817_1	580332.Slit_0725	2.313e-163	517.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,44WCS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM aminotransferase class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
YHH2_k127_781817_5	580332.Slit_0724	8.581e-41	151.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,44W1W@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF493)	ybeD	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
YHH2_k127_781817_3	580332.Slit_0723	7.671e-115	374.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,44V7A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YHH2_k127_7835651_1	713586.KB900536_gene2205	2.101e-180	577.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WWTP@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K10126,ko:K10943	ko02020,ko05111,map02020,map05111	M00504,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_7835651_4	713586.KB900536_gene2204	3.325e-116	388.0	COG4191@1|root,COG4191@2|Bacteria,1QUWB@1224|Proteobacteria,1T23G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	fleS	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
YHH2_k127_7835651_3	1209072.ALBT01000076_gene73	1.127e-149	482.0	COG3746@1|root,COG3746@2|Bacteria,1QXPF@1224|Proteobacteria,1T4CB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
YHH2_k127_7835651_7	1123257.AUFV01000002_gene2393	8.974e-33	134.0	2ENTF@1|root,33GEM@2|Bacteria,1NZ01@1224|Proteobacteria,1SPT8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7835651_5	1123256.KB907938_gene543	5.083e-111	372.0	COG2010@1|root,COG2010@2|Bacteria,1RDNN@1224|Proteobacteria,1SZ7Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
YHH2_k127_7835651_2	396588.Tgr7_0068	8.25e-154	499.0	COG2897@1|root,COG2897@2|Bacteria,1N9H9@1224|Proteobacteria,1SKTN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7835651_6	396588.Tgr7_0064	1.15e-35	137.0	COG0425@1|root,COG0425@2|Bacteria,1QSN1@1224|Proteobacteria,1SS7P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
YHH2_k127_7835651_0	396588.Tgr7_0063	1.556e-208	658.0	COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,1SH3M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YHH2_k127_7852587_1	580332.Slit_1325	9.601e-138	443.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,44V88@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
YHH2_k127_7852587_0	1163617.SCD_n01367	1.313e-230	722.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,2VHR4@28216|Betaproteobacteria	28216|Betaproteobacteria	E	aminoacyl-histidine dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YHH2_k127_7897127_8	580332.Slit_1180	1.949e-102	334.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,44VK1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
YHH2_k127_7897127_11	1387312.BAUS01000002_gene977	4.824e-38	155.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria,2KMRX@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
YHH2_k127_7897127_4	580332.Slit_1178	5.77e-213	671.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria,44V74@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
YHH2_k127_7897127_2	580332.Slit_1800	3.196e-236	745.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,44V8Y@713636|Nitrosomonadales	28216|Betaproteobacteria	O	SurA N-terminal domain	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
YHH2_k127_7897127_12	202952.BBLI01000004_gene491	1.436e-16	82.0	2DR59@1|root,33A7S@2|Bacteria,1NMH2@1224|Proteobacteria,1SIVW@1236|Gammaproteobacteria,3NS87@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7897127_10	580332.Slit_1801	5.537e-44	162.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,44W21@713636|Nitrosomonadales	28216|Betaproteobacteria	L	bacterial (prokaryotic) histone like domain	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH2_k127_7897127_0	580332.Slit_1802	0.0	1468.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,44VGG@713636|Nitrosomonadales	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH2_k127_7897127_1	580332.Slit_1803	9.08e-251	776.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,44V8T@713636|Nitrosomonadales	28216|Betaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
YHH2_k127_7897127_7	1485544.JQKP01000001_gene1139	9.751e-117	380.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,44VMK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YHH2_k127_7897127_3	580332.Slit_1805	8.16e-217	679.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,44V5B@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YHH2_k127_7897127_9	580332.Slit_0326	5.157e-87	300.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,44VQ0@713636|Nitrosomonadales	28216|Betaproteobacteria	DM	Lysin motif	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
YHH2_k127_7897127_6	580332.Slit_0325	1.868e-125	403.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,44VA5@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
YHH2_k127_7897127_5	580332.Slit_0324	2.013e-145	466.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,44V2Q@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
YHH2_k127_7897127_13	1255043.TVNIR_2320	5.867e-14	73.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
YHH2_k127_7950698_3	1049564.TevJSym_az00180	7.361e-44	161.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,1SN0X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP citrate lyase citrate-binding	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2,Citrate_bind
YHH2_k127_7950698_1	864069.MicloDRAFT_00061110	0.0	1188.0	COG0074@1|root,COG0074@2|Bacteria,1R4KP@1224|Proteobacteria,2TVFC@28211|Alphaproteobacteria,1JX4X@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Succ_CoA_lig
YHH2_k127_7950698_2	1049564.TevJSym_az00150	5.515e-202	647.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1J4QW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH2_k127_7950698_0	580332.Slit_0968	0.0	1216.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,2VI36@28216|Betaproteobacteria,44VC6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Isocitrate dehydrogenase NADP-dependent monomeric type	icd_2	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
YHH2_k127_7980673_8	580332.Slit_2488	7.249e-46	166.0	COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,2VM3P@28216|Betaproteobacteria,44W59@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YHH2_k127_7980673_6	580332.Slit_0929	3.756e-91	303.0	COG1595@1|root,COG1595@2|Bacteria,1R3SM@1224|Proteobacteria,2VS23@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_7980673_9	580332.Slit_0930	1.497e-37	143.0	2E5Q2@1|root,330EP@2|Bacteria,1NCEJ@1224|Proteobacteria,2VVYT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
YHH2_k127_7980673_5	580332.Slit_0932	6.97e-122	394.0	COG1309@1|root,COG1309@2|Bacteria,1NDME@1224|Proteobacteria,2W9PT@28216|Betaproteobacteria,44WNU@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Domain of unknown function (DUF1956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1956,TetR_N
YHH2_k127_7980673_4	580332.Slit_0933	1.219e-129	420.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria,44WFA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH2_k127_7980673_0	580332.Slit_0934	0.0	1624.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44VNU@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH2_k127_7980673_7	1132855.KB913035_gene1572	4.088e-56	199.0	COG3154@1|root,COG3154@2|Bacteria,1RB7T@1224|Proteobacteria,2VTWW@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Sterol-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
YHH2_k127_7980673_3	1132855.KB913035_gene1571	8.795e-145	469.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,2VISF@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
YHH2_k127_7980673_2	1132855.KB913035_gene1570	5.478e-190	596.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,2KNDU@206350|Nitrosomonadales	28216|Betaproteobacteria	O	Peptidase family U32 C-terminal domain	yhbU	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
YHH2_k127_7980673_1	580332.Slit_1029	1.083e-199	629.0	COG1086@1|root,COG2199@1|root,COG5000@1|root,COG1086@2|Bacteria,COG2199@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.7.7,2.7.8.33,2.7.8.35	ko:K02342,ko:K02851	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378,R08856	RC00002,RC02795	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03032,ko03400	-	-	-	CoA_binding_3,EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9,RNase_T,SpoIIE
YHH2_k127_8009331_3	580332.Slit_1321	2.279e-64	226.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,2VQQ7@28216|Betaproteobacteria,44WFY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
YHH2_k127_8009331_4	580332.Slit_1322	1.383e-52	193.0	2FG6B@1|root,3482S@2|Bacteria,1P2BQ@1224|Proteobacteria,2W87X@28216|Betaproteobacteria,44WHR@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8009331_5	395494.Galf_0407	3.313e-48	175.0	COG1858@1|root,COG1858@2|Bacteria,1QVT1@1224|Proteobacteria,2WGTP@28216|Betaproteobacteria,44WIA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
YHH2_k127_8009331_1	580332.Slit_1324	9.235e-84	281.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,44WF4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
YHH2_k127_8009331_0	1031711.RSPO_c02728	1.166e-98	338.0	COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,2VMS5@28216|Betaproteobacteria,1K3TH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
YHH2_k127_8009331_2	1123261.AXDW01000001_gene1393	2.132e-71	255.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,1S4XC@1236|Gammaproteobacteria,1X548@135614|Xanthomonadales	135614|Xanthomonadales	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH2_k127_8016290_3	395494.Galf_2398	1.47e-44	163.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2VTXZ@28216|Betaproteobacteria,44W07@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
YHH2_k127_8016290_0	580332.Slit_2143	1.111e-216	677.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,44VJQ@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	lplT	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH2_k127_8016290_2	987059.RBXJA2T_07853	2.144e-56	203.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,2VW7M@28216|Betaproteobacteria	28216|Betaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
YHH2_k127_8016290_1	580332.Slit_2142	2.751e-128	414.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria,44VAB@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
YHH2_k127_8017408_2	1249480.B649_09535	2.798e-179	583.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42NGM@68525|delta/epsilon subdivisions,2YN51@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
YHH2_k127_8017408_3	580332.Slit_2408	2.686e-174	553.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2VHA1@28216|Betaproteobacteria,44UYI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
YHH2_k127_8017408_1	580332.Slit_2409	3.719e-180	570.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,44V0Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
YHH2_k127_8017408_0	580332.Slit_2410	8.952e-265	821.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,44V6F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
YHH2_k127_8017408_4	443144.GM21_2646	5.091e-58	204.0	COG1708@1|root,COG1708@2|Bacteria,1N97U@1224|Proteobacteria	1224|Proteobacteria	S	nucleotidyltransferase substrate binding protein, HI0074 family	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,NTase_sub_bind
YHH2_k127_8017408_5	1123354.AUDR01000016_gene1353	4.86e-37	143.0	COG1708@1|root,COG1708@2|Bacteria,1QAUR@1224|Proteobacteria,2VX91@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH2_k127_8055040_5	1278309.KB907102_gene202	4.353e-30	135.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XI40@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NMT1,PAS,PAS_3,PAS_9
YHH2_k127_8055040_4	640081.Dsui_2157	1.915e-57	220.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VJV5@28216|Betaproteobacteria,2KWH2@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_4,Response_reg
YHH2_k127_8055040_3	1005048.CFU_2645	1.005e-75	267.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VME6@28216|Betaproteobacteria,478DP@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_8055040_1	697282.Mettu_1726	2.256e-127	440.0	COG3437@1|root,COG4585@1|root,COG3437@2|Bacteria,COG4585@2|Bacteria,1QWW7@1224|Proteobacteria,1T4BI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_8055040_0	697282.Mettu_1727	1.584e-159	550.0	COG0457@1|root,COG0642@1|root,COG2202@1|root,COG3437@1|root,COG0457@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,1XGYT@135618|Methylococcales	135618|Methylococcales	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_8055040_2	946483.Cenrod_1448	3.911e-89	305.0	COG3287@1|root,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,2VJQD@28216|Betaproteobacteria,4AIEG@80864|Comamonadaceae	28216|Betaproteobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
YHH2_k127_8055040_6	97138.C820_02570	2.04e-11	67.0	COG3287@1|root,COG3287@2|Bacteria,1UTWE@1239|Firmicutes,254MU@186801|Clostridia	186801|Clostridia	S	FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8055428_0	580332.Slit_1063	1.29e-257	797.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,44VBG@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YHH2_k127_8055428_4	580332.Slit_1760	9.772e-73	247.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,44VTI@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YHH2_k127_8055428_2	580332.Slit_0499	1.617e-247	780.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2VI7X@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	general secretion pathway protein D	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
YHH2_k127_8055428_1	580332.Slit_0498	3.066e-252	786.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	gspE	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH2_k127_8055428_3	580332.Slit_0497	7.926e-160	512.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,44VBF@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Type II secretion system F domain	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
YHH2_k127_8055610_2	1499967.BAYZ01000043_gene2306	2.365e-20	94.0	COG2929@1|root,COG2929@2|Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_8055610_3	933262.AXAM01000190_gene581	7.603e-14	75.0	2EMFR@1|root,33F4G@2|Bacteria,1NJ55@1224|Proteobacteria,42X7X@68525|delta/epsilon subdivisions,2WSPV@28221|Deltaproteobacteria,2MPAS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8055610_4	1284352.AOIG01000016_gene4027	5.056e-08	62.0	2B6KK@1|root,31ZJ0@2|Bacteria,1UZEE@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8055610_0	62928.azo3807	7.238e-154	492.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VKE2@28216|Betaproteobacteria,2KVZC@206389|Rhodocyclales	206389|Rhodocyclales	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	hoxB	-	1.12.7.2	ko:K00534	-	-	R00019	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
YHH2_k127_8055610_1	62928.azo3808	9.862e-133	430.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VKZS@28216|Betaproteobacteria,2KUS6@206389|Rhodocyclales	206389|Rhodocyclales	C	Nickel-dependent hydrogenase	hoxC	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
YHH2_k127_8065059_0	580332.Slit_1994	4.179e-240	745.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,44VHZ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
YHH2_k127_8065059_2	580332.Slit_1995	3.102e-89	297.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria,44V67@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	yibF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
YHH2_k127_8065059_3	580332.Slit_1996	5.93e-81	270.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,44VWV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	SelR
YHH2_k127_8065059_1	580332.Slit_1997	1.619e-89	297.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2VRHB@28216|Betaproteobacteria,44VRS@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Intracellular septation protein A	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
YHH2_k127_8065059_4	580332.Slit_1998	9.679e-46	166.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2VUM7@28216|Betaproteobacteria,44VZV@713636|Nitrosomonadales	28216|Betaproteobacteria	S	YCII-related domain	yciI	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
YHH2_k127_8127780_26	1485544.JQKP01000003_gene240	8.229e-63	217.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,44WIX@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
YHH2_k127_8127780_5	580332.Slit_1028	1.13e-274	851.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,44V0N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YHH2_k127_8127780_35	8049.ENSGMOP00000007193	2.25e-37	157.0	COG0666@1|root,KOG0504@2759|Eukaryota,39YNX@33154|Opisthokonta,3B9NB@33208|Metazoa,3CRFJ@33213|Bilateria,48ICZ@7711|Chordata,49FB1@7742|Vertebrata,49SS8@7898|Actinopterygii	33208|Metazoa	S	Ankyrin repeat domain 44	ANKRD44	-	-	ko:K15502,ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
YHH2_k127_8127780_39	1182590.BN5_02109	1.381e-14	81.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria	1224|Proteobacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
YHH2_k127_8127780_29	1283284.AZUK01000001_gene870	2.665e-59	216.0	2EFNH@1|root,339EN@2|Bacteria,1NNV3@1224|Proteobacteria,1SINQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8127780_9	580332.Slit_1085	9.547e-241	747.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,44V4J@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp
YHH2_k127_8127780_22	580332.Slit_1084	4.705e-99	326.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,44VPW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
YHH2_k127_8127780_18	580332.Slit_1573	2.3e-118	389.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,44W51@713636|Nitrosomonadales	28216|Betaproteobacteria	O	SMART band 7 protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
YHH2_k127_8127780_38	1122165.AUHS01000014_gene2783	2.746e-20	96.0	COG1585@1|root,COG1585@2|Bacteria,1N474@1224|Proteobacteria,1TD2K@1236|Gammaproteobacteria,1JG3D@118969|Legionellales	118969|Legionellales	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
YHH2_k127_8127780_8	580332.Slit_1083	2.019e-260	807.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,44VEU@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YHH2_k127_8127780_3	580332.Slit_1082	1.168e-294	907.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,44VBV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
YHH2_k127_8127780_1	580332.Slit_1081	0.0	1184.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,44V2B@713636|Nitrosomonadales	28216|Betaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
YHH2_k127_8127780_31	580332.Slit_1080	1.165e-49	178.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,44VWX@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YHH2_k127_8127780_21	580332.Slit_1079	2.217e-100	330.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,44VQ4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YHH2_k127_8127780_23	580332.Slit_1078	6.385e-95	312.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria,44V2Y@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
YHH2_k127_8127780_13	580332.Slit_1077	7.734e-202	632.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,44V52@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH2_k127_8127780_0	580332.Slit_1076	0.0	1299.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,44UZF@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
YHH2_k127_8127780_7	580332.Slit_1075	5.885e-266	820.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,44VM8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
YHH2_k127_8127780_24	580332.Slit_1074	4.402e-91	300.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria,44VSP@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YHH2_k127_8127780_6	580332.Slit_1073	1.583e-272	840.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,44V6Q@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
YHH2_k127_8127780_19	580332.Slit_1072	2.974e-115	376.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,44VSK@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
YHH2_k127_8127780_20	580332.Slit_1071	1.164e-100	330.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,44VDZ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YHH2_k127_8127780_32	580332.Slit_1069	1.004e-47	173.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,44W05@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
YHH2_k127_8127780_16	580332.Slit_1068	7.788e-129	415.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,44V2M@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
YHH2_k127_8127780_17	580332.Slit_1250	1.47e-125	404.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,2VIXH@28216|Betaproteobacteria,44VH4@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH2_k127_8127780_30	580332.Slit_1248	9.377e-53	186.0	COG2920@1|root,COG2920@2|Bacteria,1RITK@1224|Proteobacteria,2W32H@28216|Betaproteobacteria,44WIY@713636|Nitrosomonadales	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
YHH2_k127_8127780_10	580332.Slit_1247	3.909e-225	703.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,2WGS2@28216|Betaproteobacteria,44VBH@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH2_k127_8127780_36	882378.RBRH_02630	8.366e-34	131.0	COG2161@1|root,COG2161@2|Bacteria,1ND0S@1224|Proteobacteria,2VUS1@28216|Betaproteobacteria,1KAKZ@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_8127780_27	1562701.BBOF01000081_gene252	3.087e-62	220.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,2VR6N@28216|Betaproteobacteria,1KFQ1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PIN domain	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
YHH2_k127_8127780_33	338966.Ppro_2449	6.485e-46	169.0	COG1598@1|root,COG1598@2|Bacteria,1N00D@1224|Proteobacteria	1224|Proteobacteria	K	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB,HicB_lk_antitox
YHH2_k127_8127780_37	443143.GM18_1690	5.988e-24	102.0	2DS0K@1|root,33DZ7@2|Bacteria,1NKVW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_8127780_12	395494.Galf_2392	6.638e-215	671.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2VHSQ@28216|Betaproteobacteria,44W9H@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
YHH2_k127_8127780_4	395494.Galf_2393	1.527e-291	902.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,2VHFR@28216|Betaproteobacteria,44W5H@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome bd ubiquinol oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
YHH2_k127_8127780_2	580332.Slit_1383	3.583e-301	932.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,44V5V@713636|Nitrosomonadales	28216|Betaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
YHH2_k127_8127780_25	420662.Mpe_A3611	3.539e-82	284.0	COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,2WAA3@28216|Betaproteobacteria,1KNX1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8127780_28	756067.MicvaDRAFT_1261	2.468e-60	227.0	COG0515@1|root,COG0666@1|root,COG0515@2|Bacteria,COG0666@2|Bacteria,1G1JA@1117|Cyanobacteria,1HACD@1150|Oscillatoriales	1117|Cyanobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,Pkinase
YHH2_k127_8127780_11	580332.Slit_1381	2.234e-218	684.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VJXD@28216|Betaproteobacteria,44V3C@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
YHH2_k127_8127780_14	580332.Slit_1380	3.198e-152	486.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,44VBB@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YHH2_k127_8127780_34	314345.SPV1_05158	7.691e-44	164.0	COG2703@1|root,COG2703@2|Bacteria,1NHAX@1224|Proteobacteria	1224|Proteobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YHH2_k127_8127780_15	1249480.B649_01625	2.093e-143	473.0	COG2203@1|root,COG2206@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3829@2|Bacteria,1RAQS@1224|Proteobacteria,42QQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9,Response_reg,sCache_2
YHH2_k127_8145642_15	580332.Slit_2984	1.466e-86	289.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,44VX0@713636|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
YHH2_k127_8145642_16	580332.Slit_2985	1.522e-83	278.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,44VTQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
YHH2_k127_8145642_23	580332.Slit_2986	9.384e-37	139.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria,44W3S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
YHH2_k127_8145642_10	580332.Slit_2987	7.697e-161	510.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,44VW2@713636|Nitrosomonadales	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
YHH2_k127_8145642_11	580332.Slit_2989	2.119e-157	500.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,44V9B@713636|Nitrosomonadales	28216|Betaproteobacteria	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YHH2_k127_8145642_12	580332.Slit_2990	5.919e-155	491.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,44VF0@713636|Nitrosomonadales	28216|Betaproteobacteria	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YHH2_k127_8145642_13	580332.Slit_2991	2.642e-106	350.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,44VPZ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
YHH2_k127_8145642_1	580332.Slit_2992	0.0	1129.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,44V4F@713636|Nitrosomonadales	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
YHH2_k127_8145642_8	1485544.JQKP01000007_gene1999	1.781e-179	572.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2VHCJ@28216|Betaproteobacteria,44V9H@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
YHH2_k127_8145642_3	580332.Slit_2994	4.026e-271	842.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,44V1I@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
YHH2_k127_8145642_24	580332.Slit_2995	1.25e-34	133.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,44W1S@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
YHH2_k127_8145642_21	580332.Slit_2996	4.643e-38	146.0	COG0594@1|root,COG0594@2|Bacteria,1PXBW@1224|Proteobacteria,2WCTM@28216|Betaproteobacteria,44WN7@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribonuclease P	-	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
YHH2_k127_8145642_25	580332.Slit_2997	7.848e-19	86.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2VXTS@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
YHH2_k127_8145642_9	395494.Galf_0001	2.149e-174	559.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria,44W93@713636|Nitrosomonadales	28216|Betaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
YHH2_k127_8145642_7	580332.Slit_0002	7.229e-194	610.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,44W9E@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
YHH2_k127_8145642_0	580332.Slit_0003	0.0	1556.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,44WB9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH2_k127_8145642_14	1121035.AUCH01000013_gene3117	1.509e-97	321.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,2VP9C@28216|Betaproteobacteria,2KVUT@206389|Rhodocyclales	206389|Rhodocyclales	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
YHH2_k127_8145642_5	1163617.SCD_n01156	3.112e-215	681.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2VKHA@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
YHH2_k127_8145642_17	1163617.SCD_n01157	1.009e-74	255.0	COG3439@1|root,COG3439@2|Bacteria,1N4Z5@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
YHH2_k127_8145642_22	580332.Slit_0803	4.874e-38	146.0	COG1433@1|root,COG1433@2|Bacteria,1N7S0@1224|Proteobacteria,2WG9K@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
YHH2_k127_8145642_20	1163617.SCD_n01738	2.183e-43	162.0	2E94J@1|root,333DE@2|Bacteria,1N7Q9@1224|Proteobacteria,2VXHD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8145642_4	580332.Slit_0416	1.095e-252	785.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,44VFR@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM cytochrome c oxidase accessory protein CcoG	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
YHH2_k127_8145642_19	580332.Slit_0802	2.465e-44	161.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,44W12@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
YHH2_k127_8145642_6	580332.Slit_0801	9.554e-215	674.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VHQS@28216|Betaproteobacteria,44WPB@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS_4,Sigma54_activat
YHH2_k127_8145642_2	1163617.SCD_n00326	0.0	1005.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Abc transporter	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH2_k127_8238488_18	580332.Slit_2231	4.003e-62	217.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,44VGQ@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
YHH2_k127_8238488_26	1150621.SMUL_1240	5.466e-27	117.0	COG3744@1|root,COG3744@2|Bacteria,1RJXF@1224|Proteobacteria,431F2@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_8238488_3	580332.Slit_2232	4.893e-250	782.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,2VQE0@28216|Betaproteobacteria,44WFJ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS_4
YHH2_k127_8238488_24	686340.Metal_0407	2.184e-34	133.0	2DQ4M@1|root,334QD@2|Bacteria,1NC4H@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH2_k127_8238488_22	522306.CAP2UW1_0834	5.769e-37	141.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,2VXC1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
YHH2_k127_8238488_32	62928.azo1372	2.278e-05	48.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_8238488_4	296591.Bpro_5422	3.353e-204	640.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,2VMP0@28216|Betaproteobacteria,4AF5C@80864|Comamonadaceae	28216|Betaproteobacteria	L	Domain of unknown function (DUF4372)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH2_k127_8238488_0	1485544.JQKP01000002_gene1598	0.0	1918.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,44UYD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
YHH2_k127_8238488_5	580332.Slit_2276	9.824e-198	621.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2VJSV@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	camA	-	1.18.1.3	ko:K00529,ko:K18227,ko:K18249	ko00071,ko00360,ko00622,ko00627,ko01120,ko01220,map00071,map00360,map00622,map00627,map01120,map01220	M00539,M00545,M00637	R00823,R00825,R02000,R05247,R06782,R06783	RC00098,RC00192,RC00267	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
YHH2_k127_8238488_28	324925.Ppha_0884	2.958e-22	98.0	2DPW4@1|root,333N7@2|Bacteria	2|Bacteria	S	TIGRFAM YgiT-type zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8238488_23	448385.sce5398	6.938e-35	136.0	arCOG07672@1|root,31B2K@2|Bacteria,1Q6SM@1224|Proteobacteria,433QJ@68525|delta/epsilon subdivisions,2WY85@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
YHH2_k127_8238488_21	1163617.SCD_n00963	6.159e-38	151.0	2DCSQ@1|root,2ZF73@2|Bacteria,1PBH0@1224|Proteobacteria,2W680@28216|Betaproteobacteria	28216|Betaproteobacteria	S	STAS-like domain of unknown function (DUF4325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4325
YHH2_k127_8238488_31	399741.Spro_3526	3.315e-07	56.0	COG3668@1|root,COG3668@2|Bacteria,1PZJT@1224|Proteobacteria,1TB9G@1236|Gammaproteobacteria,405F8@613|Serratia	1236|Gammaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_8238488_7	658612.MD26_04795	5.816e-139	448.0	COG1715@1|root,COG1715@2|Bacteria,1R3ZM@1224|Proteobacteria	1224|Proteobacteria	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF3644,Mrr_cat
YHH2_k127_8238488_29	666681.M301_2545	3.315e-17	85.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,2KKD7@206350|Nitrosomonadales	206350|Nitrosomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
YHH2_k127_8238488_8	314285.KT71_17656	7.957e-137	445.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria,1JAET@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH2_k127_8238488_1	580332.Slit_0798	0.0	1785.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,44VAW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH2_k127_8238488_13	580332.Slit_0797	1.318e-83	280.0	COG2340@1|root,COG2340@2|Bacteria,1RI4E@1224|Proteobacteria,2VX53@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains.	-	-	-	-	-	-	-	-	-	-	-	-	CAP
YHH2_k127_8238488_16	580332.Slit_0794	6.324e-73	247.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2VR6I@28216|Betaproteobacteria,44VXK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
YHH2_k127_8238488_6	580332.Slit_0793	4.911e-192	603.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria,44V49@713636|Nitrosomonadales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YHH2_k127_8238488_9	580332.Slit_0792	1.502e-122	394.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,44VAX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
YHH2_k127_8238488_14	580332.Slit_0791	8.801e-77	257.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,44VTB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YHH2_k127_8238488_17	580332.Slit_0790	3.303e-66	226.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,44VVQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YHH2_k127_8238488_30	580332.Slit_0789	8.905e-16	78.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,2VXPQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
YHH2_k127_8238488_20	580332.Slit_0788	1.954e-39	146.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU9X@28216|Betaproteobacteria,44W0J@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
YHH2_k127_8238488_2	580332.Slit_0787	3.568e-257	795.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,44VIZ@713636|Nitrosomonadales	28216|Betaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YHH2_k127_8238488_15	580332.Slit_0786	6.936e-74	250.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,44VVB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
YHH2_k127_8238488_25	580332.Slit_0785	6.622e-34	130.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,44W34@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
YHH2_k127_8238488_11	580332.Slit_0784	1.985e-99	325.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,44VR0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
YHH2_k127_8238488_19	580332.Slit_0783	2.184e-61	214.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,44W0K@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
YHH2_k127_8238488_12	580332.Slit_0782	2.444e-92	305.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,44VQK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
YHH2_k127_8267368_1	580332.Slit_2080	3.6e-179	569.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YHH2_k127_8267368_2	580332.Slit_2079	3.133e-128	415.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJBY@28216|Betaproteobacteria,44VNJ@713636|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_8267368_0	580332.Slit_2078	1.897e-216	676.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria,44V5Z@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_8283349_3	580332.Slit_0979	1.059e-43	162.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,44V32@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
YHH2_k127_8283349_1	1485544.JQKP01000001_gene1315	1.43e-275	854.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2VJZN@28216|Betaproteobacteria,44VIH@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
YHH2_k127_8283349_2	395494.Galf_1320	3.598e-265	820.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,44VMQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
YHH2_k127_8283349_0	580332.Slit_1395	0.0	1350.0	COG2202@1|root,COG3447@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3447@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WDA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE1,PAS_3,PAS_9
YHH2_k127_8283349_4	395494.Galf_1646	4.002e-39	152.0	2AJXH@1|root,31AKJ@2|Bacteria,1RJPF@1224|Proteobacteria,2VTF5@28216|Betaproteobacteria,44W13@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
YHH2_k127_8285403_1	580332.Slit_0036	2.361e-227	707.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2VHU9@28216|Betaproteobacteria,44V9X@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metXS	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
YHH2_k127_8285403_6	580332.Slit_0035	3.264e-112	364.0	COG2890@1|root,COG2890@2|Bacteria,1R0WI@1224|Proteobacteria	1224|Proteobacteria	J	TIGRFAM methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	MetW
YHH2_k127_8285403_13	85643.Tmz1t_1066	8.392e-28	115.0	COG2161@1|root,COG2161@2|Bacteria,1Q0YS@1224|Proteobacteria,2W5WQ@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_8285403_12	1266908.AQPB01000055_gene1939	1.125e-48	177.0	COG1569@1|root,COG1569@2|Bacteria,1N9YY@1224|Proteobacteria,1TAHR@1236|Gammaproteobacteria,1X1Q0@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH2_k127_8285403_0	395494.Galf_0126	2.148e-231	732.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria,44VM1@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
YHH2_k127_8285403_14	312153.Pnuc_0687	2.484e-26	109.0	COG4456@1|root,COG4456@2|Bacteria,1N7E4@1224|Proteobacteria,2VW9G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
YHH2_k127_8285403_10	1387312.BAUS01000002_gene583	7.719e-59	207.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,2VWH6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH2_k127_8285403_7	580332.Slit_0032	2.828e-93	314.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	yjdF	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
YHH2_k127_8285403_4	580332.Slit_0031	2.401e-147	469.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,44V0I@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
YHH2_k127_8285403_5	580332.Slit_0030	1.69e-122	394.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,2VH9U@28216|Betaproteobacteria,44VM2@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YHH2_k127_8285403_11	580332.Slit_0029	2.829e-50	185.0	2DPC5@1|root,331GN@2|Bacteria,1NCRC@1224|Proteobacteria,2VVUT@28216|Betaproteobacteria,44W1H@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
YHH2_k127_8285403_8	580332.Slit_0028	3.824e-93	310.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VR34@28216|Betaproteobacteria,44VSI@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Carbonic anhydrase	cynT	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
YHH2_k127_8285403_3	580332.Slit_0027	5.561e-182	570.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,44VFI@713636|Nitrosomonadales	28216|Betaproteobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
YHH2_k127_8285403_9	580332.Slit_0026	2.58e-89	295.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,44VPK@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YHH2_k127_8285403_2	580332.Slit_0025	9.356e-192	599.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,44V03@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
YHH2_k127_8318660_2	580332.Slit_0705	3.277e-25	105.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,44V0J@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH2_k127_8318660_1	580332.Slit_0704	1.428e-31	126.0	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,44W3B@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
YHH2_k127_8318660_0	580332.Slit_0703	7.68e-225	703.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,44VG4@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	alcE	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
YHH2_k127_8320088_6	2903.EOD31047	1.709e-15	88.0	2EMZ8@1|root,2SRHU@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8320088_7	580332.Slit_2018	1.369e-11	66.0	2DBSM@1|root,32TY0@2|Bacteria,1N5UN@1224|Proteobacteria,2VV1Y@28216|Betaproteobacteria,44WI0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
YHH2_k127_8320088_11	331678.Cphamn1_0882	0.0005174	53.0	2CBT6@1|root,2ZFGY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8320088_8	388051.AUFE01000036_gene4024	3.861e-11	64.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,2VRK1@28216|Betaproteobacteria	28216|Betaproteobacteria	K	regulator	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
YHH2_k127_8320088_2	743299.Acife_0044	1.228e-46	168.0	COG2929@1|root,COG2929@2|Bacteria,1N3AZ@1224|Proteobacteria,1SQ13@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_8320088_4	83406.HDN1F_26640	2.426e-23	99.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,1S4IJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
YHH2_k127_8320088_5	1294143.H681_13275	7.141e-20	89.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,1S4IJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
YHH2_k127_8320088_9	697282.Mettu_3274	1.062e-07	57.0	COG3514@1|root,COG3514@2|Bacteria,1NMDA@1224|Proteobacteria,1SI7C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
YHH2_k127_8320088_3	580332.Slit_1603	1.415e-29	119.0	COG2929@1|root,COG2929@2|Bacteria,1PUH4@1224|Proteobacteria,2VX5T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_8320088_1	243365.CV_2432	3.499e-75	271.0	COG1407@1|root,COG1407@2|Bacteria,1N407@1224|Proteobacteria,2VV01@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH2_k127_8320088_0	1218084.BBJK01000073_gene5123	3.049e-100	351.0	COG4995@1|root,COG4995@2|Bacteria,1QXRY@1224|Proteobacteria,2VPZZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
YHH2_k127_8361806_2	187272.Mlg_1124	3.154e-38	145.0	COG0507@1|root,COG1974@1|root,COG3410@1|root,COG0507@2|Bacteria,COG1974@2|Bacteria,COG3410@2|Bacteria,1R703@1224|Proteobacteria,1RY5E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075
YHH2_k127_8361806_0	1123237.Salmuc_00331	1.862e-214	676.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG4584 Transposase and inactivated derivatives	istA	-	-	-	-	-	-	-	-	-	-	-	rve
YHH2_k127_8361806_1	34007.IT40_20955	4.641e-120	390.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TRGY@28211|Alphaproteobacteria,2PW77@265|Paracoccus	28211|Alphaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
YHH2_k127_837529_4	580332.Slit_2148	4.777e-122	393.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,2WAP5@28216|Betaproteobacteria,44WER@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
YHH2_k127_837529_3	1485544.JQKP01000009_gene850	2.39e-145	464.0	COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,2VJ0H@28216|Betaproteobacteria,44WBT@713636|Nitrosomonadales	28216|Betaproteobacteria	DT	RIO1 family	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
YHH2_k127_837529_8	1499686.BN1079_01386	8.283e-35	134.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,1SCBX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	ypeB	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
YHH2_k127_837529_2	331678.Cphamn1_0718	1.191e-175	558.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,TniB
YHH2_k127_837529_6	580332.Slit_2774	3.164e-70	241.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria,44WGK@713636|Nitrosomonadales	28216|Betaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
YHH2_k127_837529_7	765912.Thimo_1718	6.508e-41	153.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1SCYV@1236|Gammaproteobacteria,1WYTT@135613|Chromatiales	135613|Chromatiales	K	TIGRFAM Addiction module antidote protein, HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
YHH2_k127_837529_9	756272.Plabr_1133	8.835e-22	102.0	2C6MB@1|root,32952@2|Bacteria,2J4M7@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_837529_0	580332.Slit_0856	2.011e-303	934.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,2WHK4@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Nif-specific regulatory protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
YHH2_k127_837529_11	62928.azo3097	2.219e-05	50.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,2KUMB@206389|Rhodocyclales	206389|Rhodocyclales	P	Von Willebrand factor type A	norD	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA
YHH2_k127_837529_1	580332.Slit_0857	1.418e-265	825.0	COG4191@1|root,COG4191@2|Bacteria,1MXRR@1224|Proteobacteria,2VN7B@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PAS PAC sensor signal transduction histidine kinase	-	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,PAS
YHH2_k127_837529_5	580332.Slit_0858	9.91e-88	293.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,2VH0C@28216|Betaproteobacteria,44VIU@713636|Nitrosomonadales	1224|Proteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
YHH2_k127_837529_10	580332.Slit_0859	5.986e-21	93.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,44VN8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
YHH2_k127_8394526_2	1163617.SCD_n02138	5.653e-53	192.0	COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,2VHWD@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs	dusC	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
YHH2_k127_8394526_0	666681.M301_1790	7.249e-195	612.0	COG0640@1|root,COG3177@1|root,COG0640@2|Bacteria,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2VIY1@28216|Betaproteobacteria,2KN68@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Fic/DOC family N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
YHH2_k127_8394526_1	1117647.M5M_16400	8.13e-57	203.0	COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,1S39N@1236|Gammaproteobacteria,1JB1B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
YHH2_k127_8438010_12	580332.Slit_1648	1.046e-42	156.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,44VJI@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
YHH2_k127_8438010_8	395494.Galf_1791	1.92e-133	427.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,44VAA@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YHH2_k127_8438010_5	580332.Slit_1650	4.026e-166	525.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,44VIJ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
YHH2_k127_8438010_7	580332.Slit_1651	2.399e-139	448.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2VI8V@28216|Betaproteobacteria,44V8R@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YHH2_k127_8438010_4	580332.Slit_1540	1.237e-181	571.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,44W72@713636|Nitrosomonadales	28216|Betaproteobacteria	BQ	PFAM histone deacetylase superfamily	hda	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
YHH2_k127_8438010_0	580332.Slit_1541	0.0	1647.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,44WDS@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM CoA-binding domain protein	yfiQ	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
YHH2_k127_8438010_11	580332.Slit_1612	9.257e-58	204.0	COG0680@1|root,COG0680@2|Bacteria,1MZE1@1224|Proteobacteria,2VTPX@28216|Betaproteobacteria,44WKQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	hydrogenase maturation protease	hoxW	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8438010_3	580332.Slit_1611	2.794e-306	941.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2VJT0@28216|Betaproteobacteria,44WEG@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hoxH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
YHH2_k127_8438010_14	395493.BegalDRAFT_3314	3.734e-30	125.0	COG5573@1|root,COG5573@2|Bacteria,1N3BU@1224|Proteobacteria,1S9WU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM PilT protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_8438010_17	522306.CAP2UW1_0740	4.603e-06	51.0	2EQJE@1|root,33NDE@2|Bacteria,1NQ9R@1224|Proteobacteria,2W5B3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2281
YHH2_k127_8438010_10	580332.Slit_1610	2.147e-116	381.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,2VJH8@28216|Betaproteobacteria,44WAW@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	hoxY	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
YHH2_k127_8438010_6	580332.Slit_1609	1.265e-144	462.0	COG1034@1|root,COG1034@2|Bacteria,1QVC7@1224|Proteobacteria,2VI6U@28216|Betaproteobacteria,44W9N@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	hoxU	-	1.12.1.2	ko:K18006	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_4,Fer4_15,NADH-G_4Fe-4S_3
YHH2_k127_8438010_2	580332.Slit_1608	0.0	1040.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VHW2@28216|Betaproteobacteria,44W82@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding	hoxF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
YHH2_k127_8438010_13	472759.Nhal_1738	1.493e-34	136.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8438010_15	472759.Nhal_1737	3.385e-24	104.0	COG2442@1|root,COG2442@2|Bacteria,1N8Z1@1224|Proteobacteria,1SC0G@1236|Gammaproteobacteria,1WZ65@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YHH2_k127_8438010_9	1232683.ADIMK_2673	1.357e-132	451.0	COG2199@1|root,COG2203@1|root,COG4936@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4936@2|Bacteria,1R7HC@1224|Proteobacteria,1RYYR@1236|Gammaproteobacteria,46AFI@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	PAS PAC and GAF sensor-containing diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,GGDEF,PAS_3,PAS_4,PAS_8,PocR
YHH2_k127_8438010_16	395495.Lcho_2140	3.577e-10	60.0	COG4680@1|root,COG4680@2|Bacteria	2|Bacteria	K	protein conserved in bacteria	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
YHH2_k127_8438010_1	580332.Slit_1520	0.0	1210.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,44VBY@713636|Nitrosomonadales	28216|Betaproteobacteria	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YHH2_k127_8443392_2	543913.D521_0764	8.161e-48	174.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
YHH2_k127_8443392_1	543913.D521_0763	1.194e-94	314.0	COG0765@1|root,COG0765@2|Bacteria,1MUVX@1224|Proteobacteria,2VJ8A@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
YHH2_k127_8443392_0	543913.D521_0762	3.699e-120	391.0	COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,2VJ9K@28216|Betaproteobacteria,1KR2E@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	ET	Ligated ion channel L-glutamate- and glycine-binding site	-	-	-	ko:K02030,ko:K10036	ko02010,map02010	M00227,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.2	-	-	SBP_bac_3
YHH2_k127_8467488_16	357808.RoseRS_3212	5.661e-51	186.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
YHH2_k127_8467488_15	864051.BurJ1DRAFT_2735	9.529e-52	191.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
YHH2_k127_8467488_10	517417.Cpar_0822	1.028e-100	334.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.144,2.1.1.197	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
YHH2_k127_8467488_23	1121940.AUDZ01000007_gene2175	3.007e-14	78.0	2E6JT@1|root,3316P@2|Bacteria,1N9SN@1224|Proteobacteria,1SDZF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8467488_24	388413.ALPR1_16064	0.0003927	49.0	COG1396@1|root,COG1396@2|Bacteria,4NUWD@976|Bacteroidetes,47S35@768503|Cytophagia	976|Bacteroidetes	K	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870,HTH_3
YHH2_k127_8467488_20	765911.Thivi_1538	3.009e-24	107.0	2EIG1@1|root,33C7D@2|Bacteria,1NNA9@1224|Proteobacteria,1SH4C@1236|Gammaproteobacteria,1X1KH@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8467488_21	195250.CM001776_gene2660	9.754e-22	100.0	COG0789@1|root,COG0789@2|Bacteria,1G6K7@1117|Cyanobacteria,1H11Q@1129|Synechococcus	1117|Cyanobacteria	K	Transcriptional Regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
YHH2_k127_8467488_18	1217652.F954_02443	3.489e-37	154.0	COG0451@1|root,COG0451@2|Bacteria,1RKZT@1224|Proteobacteria,1S4B4@1236|Gammaproteobacteria,3NJQD@468|Moraxellaceae	1236|Gammaproteobacteria	M	Male sterility protein	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Epimerase,NAD_binding_4
YHH2_k127_8467488_14	296591.Bpro_3939	1.956e-61	217.0	COG1077@1|root,COG1077@2|Bacteria,1RK8H@1224|Proteobacteria,2VT45@28216|Betaproteobacteria,4AESU@80864|Comamonadaceae	28216|Betaproteobacteria	D	MreB/Mbl protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH2_k127_8467488_7	580332.Slit_2944	1.076e-135	436.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,44VQY@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
YHH2_k127_8467488_9	580332.Slit_2943	6.018e-105	342.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,2VN9B@28216|Betaproteobacteria,44VDM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH2_k127_8467488_2	580332.Slit_2942	4.633e-259	802.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2VIH1@28216|Betaproteobacteria,44W83@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM TrkA-N domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
YHH2_k127_8467488_3	395494.Galf_0133	3.062e-242	755.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,44W7S@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
YHH2_k127_8467488_12	580332.Slit_2940	6.202e-68	232.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,2VR2Q@28216|Betaproteobacteria,44WGJ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	cheY-homologous receiver domain	pilG	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
YHH2_k127_8467488_17	1121035.AUCH01000003_gene1375	1.508e-48	175.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria,2KWTI@206389|Rhodocyclales	206389|Rhodocyclales	T	response regulator receiver	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
YHH2_k127_8467488_13	580332.Slit_2938	4.066e-65	226.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria,44WGG@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
YHH2_k127_8467488_6	1485544.JQKP01000007_gene2025	2.185e-190	616.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,44W5A@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	histidine kinase HAMP region domain protein	pilJ	-	-	ko:K02660,ko:K03406	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
YHH2_k127_8467488_0	580332.Slit_2936	0.0	2096.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,44W8H@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
YHH2_k127_8467488_19	1163617.SCD_n00500	1.754e-28	120.0	COG3255@1|root,COG3255@2|Bacteria,1N93W@1224|Proteobacteria,2WHTH@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
YHH2_k127_8467488_8	580332.Slit_2935	2.527e-111	361.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,44VSQ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
YHH2_k127_8467488_11	580332.Slit_2933	4.816e-73	251.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria,44VTU@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
YHH2_k127_8467488_5	580332.Slit_2932	5.136e-191	598.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,44VME@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YHH2_k127_8467488_4	580332.Slit_2931	2.835e-237	743.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,44V6X@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Amidohydrolase family	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
YHH2_k127_8467488_1	395494.Galf_0139	0.0	1122.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria,44VER@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
YHH2_k127_8475994_0	1000565.METUNv1_02811	8.859e-103	358.0	COG4585@1|root,COG4585@2|Bacteria,1R1TC@1224|Proteobacteria,2VHUA@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA_3
YHH2_k127_8475994_1	1182590.BN5_03571	3.583e-06	49.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,1RQHU@1236|Gammaproteobacteria,1YF58@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
YHH2_k127_8518282_1	580332.Slit_1350	2.081e-149	477.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,44VG8@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
YHH2_k127_8518282_2	580332.Slit_1351	3.943e-145	464.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VICP@28216|Betaproteobacteria,44VDG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YHH2_k127_8518282_0	580332.Slit_0266	0.0	1444.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria,44V53@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
YHH2_k127_8518282_3	580332.Slit_0267	9.164e-132	422.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,44V8C@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
YHH2_k127_8518446_1	1485544.JQKP01000001_gene1021	5.626e-83	279.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,44VTD@713636|Nitrosomonadales	28216|Betaproteobacteria	V	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
YHH2_k127_8518446_2	205918.Psyr_3089	1.087e-10	71.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1Z902@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	Q	Haemolysin-type calcium binding protein related domain	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,He_PIG,HemolysinCabind,Laminin_G_3
YHH2_k127_8518446_0	1033802.SSPSH_001659	3.33e-109	360.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_8522002_0	395494.Galf_1704	2.359e-159	508.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,44VM5@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
YHH2_k127_8522002_1	395494.Galf_1705	3.124e-151	485.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,44VMP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Rhodanese Homology Domain	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
YHH2_k127_8551029_13	232721.Ajs_2200	2.199e-07	52.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,2VKAK@28216|Betaproteobacteria,4AJKJ@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3
YHH2_k127_8551029_8	1485544.JQKP01000012_gene2109	2.804e-36	139.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,2VKGK@28216|Betaproteobacteria,44WAC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Phospholipase A1	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
YHH2_k127_8551029_2	395494.Galf_0294	2.018e-198	625.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2WGFR@28216|Betaproteobacteria,44V5P@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Domain of unknown function DUF21	corB	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
YHH2_k127_8551029_1	580332.Slit_2699	7.309e-210	657.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,44VBF@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Type II secretion system F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH2_k127_8551029_4	580332.Slit_2700	9.091e-156	494.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,44VHU@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
YHH2_k127_8551029_7	580332.Slit_2701	3.578e-67	239.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,44VX1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
YHH2_k127_8551029_6	580332.Slit_2702	2.112e-124	402.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,2VIIG@28216|Betaproteobacteria,44VMD@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
YHH2_k127_8551029_9	580332.Slit_2703	6.006e-22	104.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VXRV@28216|Betaproteobacteria,44W1E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
YHH2_k127_8551029_5	580332.Slit_2704	1.006e-154	494.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria,44V8D@713636|Nitrosomonadales	28216|Betaproteobacteria	HL	Thiamine monophosphate synthase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
YHH2_k127_8551029_3	580332.Slit_0427	8.411e-181	572.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,44VDA@713636|Nitrosomonadales	28216|Betaproteobacteria	L	endonuclease III	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
YHH2_k127_8551029_0	580332.Slit_0426	0.0	1024.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,44W58@713636|Nitrosomonadales	28216|Betaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
YHH2_k127_8631921_1	1485544.JQKP01000005_gene333	2.585e-299	924.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,2VHBK@28216|Betaproteobacteria,44VR5@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
YHH2_k127_8631921_2	202954.BBNK01000027_gene3676	1.246e-120	400.0	COG0732@1|root,COG0732@2|Bacteria,1MXSQ@1224|Proteobacteria,1S320@1236|Gammaproteobacteria,3NNQM@468|Moraxellaceae	1236|Gammaproteobacteria	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
YHH2_k127_8631921_3	1380387.JADM01000013_gene1350	4.892e-98	327.0	COG3654@1|root,COG3943@1|root,COG3654@2|Bacteria,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,1RPNB@1236|Gammaproteobacteria,1XIB0@135619|Oceanospirillales	135619|Oceanospirillales	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
YHH2_k127_8631921_6	259536.Psyc_1088	5.33e-30	122.0	COG3654@1|root,COG3654@2|Bacteria,1QXGS@1224|Proteobacteria	1224|Proteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH2_k127_8631921_5	1485544.JQKP01000005_gene335	2.589e-44	162.0	COG1669@1|root,COG5340@1|root,COG1669@2|Bacteria,COG5340@2|Bacteria,1N5A8@1224|Proteobacteria,2VXZ7@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
YHH2_k127_8631921_4	1485544.JQKP01000005_gene336	2.488e-53	189.0	COG2361@1|root,COG2361@2|Bacteria,1PTAN@1224|Proteobacteria,2VXNS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
YHH2_k127_8631921_0	1485544.JQKP01000005_gene337	0.0	1131.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,44VE5@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
YHH2_k127_8641333_5	1038866.KB902813_gene2063	5.88e-92	308.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,2TWST@28211|Alphaproteobacteria,3JUB4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YHH2_k127_8641333_3	1005048.CFU_0111	1.011e-111	367.0	COG1335@1|root,COG1335@2|Bacteria,1RCGZ@1224|Proteobacteria,2VKAA@28216|Betaproteobacteria,472V9@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	COG1335 Amidases related to nicotinamidase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
YHH2_k127_8641333_1	546274.EIKCOROL_01264	1.615e-150	485.0	COG1488@1|root,COG1488@2|Bacteria,1MV8U@1224|Proteobacteria,2VGZ5@28216|Betaproteobacteria,2KQ8D@206351|Neisseriales	206351|Neisseriales	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
YHH2_k127_8641333_0	1121035.AUCH01000006_gene662	3.413e-261	814.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VKQR@28216|Betaproteobacteria,2KY06@206389|Rhodocyclales	206389|Rhodocyclales	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
YHH2_k127_8641333_2	1121035.AUCH01000006_gene663	3.319e-138	447.0	COG1051@1|root,COG1056@1|root,COG1051@2|Bacteria,COG1056@2|Bacteria,1MWNH@1224|Proteobacteria,2VMGH@28216|Betaproteobacteria,2KXQY@206389|Rhodocyclales	206389|Rhodocyclales	FH	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,NUDIX
YHH2_k127_8641333_4	580332.Slit_2227	1.623e-94	317.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,44VSC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH2_k127_8641333_6	580332.Slit_2228	2.829e-66	229.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,44W02@713636|Nitrosomonadales	28216|Betaproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789,ko:K14742	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
YHH2_k127_8641333_7	292415.Tbd_1725	1.275e-05	47.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,1KRSM@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
YHH2_k127_8745480_10	580332.Slit_0004	9.238e-24	101.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,44UZ5@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
YHH2_k127_8745480_6	580332.Slit_0005	1.251e-81	274.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,2VRJF@28216|Betaproteobacteria,44VVY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF494)	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
YHH2_k127_8745480_2	580332.Slit_0006	1.202e-164	524.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,44VI9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA recombination-mediator protein A	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
YHH2_k127_8745480_3	580332.Slit_0007	5.308e-139	451.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,44VKI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
YHH2_k127_8745480_7	580332.Slit_0008	2.157e-73	251.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,44VPM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
YHH2_k127_8745480_4	580332.Slit_0009	2.146e-123	402.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,44V35@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YHH2_k127_8745480_1	580332.Slit_0010	2.9e-181	576.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,44VEQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
YHH2_k127_8745480_8	1485544.JQKP01000002_gene1577	9.98e-43	165.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,44VWB@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
YHH2_k127_8745480_0	580332.Slit_0012	3.438e-296	923.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,44UYE@713636|Nitrosomonadales	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_7,PAS_8
YHH2_k127_8745480_5	580332.Slit_0013	2.649e-105	346.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,44UZG@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Bacterial regulatory protein, Fis family	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
YHH2_k127_8745480_9	580332.Slit_0014	8.548e-36	136.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,44VJX@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
YHH2_k127_8816526_2	580332.Slit_2156	9.762e-81	271.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2VRQB@28216|Betaproteobacteria,44WFC@713636|Nitrosomonadales	28216|Betaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8816526_1	580332.Slit_2157	1.168e-207	663.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,44WD0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
YHH2_k127_8816526_0	666681.M301_1274	9.958e-226	741.0	COG1404@1|root,COG3420@1|root,COG1404@2|Bacteria,COG3420@2|Bacteria,1NGRY@1224|Proteobacteria,2VK0R@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Polymer-forming cytoskeletal	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Bactofilin,Laminin_G_3
YHH2_k127_8844983_0	580332.Slit_2243	4.5e-226	707.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44V4Y@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
YHH2_k127_8844983_16	580332.Slit_0451	8.19e-31	123.0	2CHG9@1|root,3332K@2|Bacteria,1NCD5@1224|Proteobacteria,2VWRB@28216|Betaproteobacteria,44W1I@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8844983_2	580332.Slit_0452	7.878e-179	567.0	COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
YHH2_k127_8844983_3	580332.Slit_0453	9.187e-134	438.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,2VNXD@28216|Betaproteobacteria,44VHY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
YHH2_k127_8844983_9	580332.Slit_0454	5.498e-96	320.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,44VXV@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33,6.3.4.15	ko:K01947,ko:K03525	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000	-	-	-	BPL_C,BPL_LplA_LipB,Pan_kinase
YHH2_k127_8844983_11	580332.Slit_0455	6.817e-65	236.0	2DP0A@1|root,3300Q@2|Bacteria,1N78Y@1224|Proteobacteria,2VVZ5@28216|Betaproteobacteria,44VYM@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
YHH2_k127_8844983_7	1485544.JQKP01000005_gene371	3.176e-99	332.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria,44VH0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
YHH2_k127_8844983_5	580332.Slit_0517	9.725e-121	389.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,44VN7@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
YHH2_k127_8844983_12	580332.Slit_0518	4.715e-58	205.0	COG0848@1|root,COG0848@2|Bacteria,1RGWR@1224|Proteobacteria,2VT20@28216|Betaproteobacteria,44VVP@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
YHH2_k127_8844983_13	580332.Slit_0519	8.149e-52	192.0	COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,2VKUS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TIGRFAM TonB family protein	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
YHH2_k127_8844983_8	1266925.JHVX01000001_gene2469	7.076e-98	325.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,2VKZ3@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_8844983_14	1454004.AW11_01193	6.363e-36	150.0	COG1864@1|root,COG2931@1|root,COG3179@1|root,COG3209@1|root,COG3391@1|root,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3179@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,1RC1P@1224|Proteobacteria,2VUZC@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19
YHH2_k127_8844983_1	580332.Slit_0520	4.425e-195	615.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,44V5U@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
YHH2_k127_8844983_15	580332.Slit_0521	9.485e-35	140.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,44W03@713636|Nitrosomonadales	28216|Betaproteobacteria	M	OmpA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
YHH2_k127_8844983_10	580332.Slit_0522	4.791e-83	283.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,44VUU@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
YHH2_k127_8844983_6	580332.Slit_0523	5.801e-119	384.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,44VIV@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
YHH2_k127_8844983_4	580332.Slit_0524	2.895e-124	401.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,44V5Y@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
YHH2_k127_9011078_13	1449346.JQMO01000002_gene717	5.866e-48	184.0	COG4932@1|root,COG4932@2|Bacteria,2GJ4T@201174|Actinobacteria,2M3N0@2063|Kitasatospora	201174|Actinobacteria	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,DUF3494,TIG
YHH2_k127_9011078_17	338969.Rfer_3274	2.031e-17	83.0	COG3237@1|root,COG3237@2|Bacteria,1NGW6@1224|Proteobacteria,2VXPK@28216|Betaproteobacteria,4AFXD@80864|Comamonadaceae	28216|Betaproteobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
YHH2_k127_9011078_6	290317.Cpha266_0793	5.498e-96	320.0	COG2201@1|root,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	-	2.1.1.80,3.1.1.61,3.5.1.44	ko:K03412,ko:K03413,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_9,Response_reg
YHH2_k127_9011078_15	1121035.AUCH01000008_gene1046	2.592e-38	146.0	2EQH0@1|root,33I30@2|Bacteria,1NJ7T@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9011078_1	580332.Slit_1982	5.576e-222	697.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,44VGE@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
YHH2_k127_9011078_2	580332.Slit_1983	1.156e-181	572.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2WEDQ@28216|Betaproteobacteria,44VB3@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
YHH2_k127_9011078_4	580332.Slit_1984	5.336e-112	364.0	COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
YHH2_k127_9011078_8	580332.Slit_1985	2.937e-87	292.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2VNUN@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	DSBA Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
YHH2_k127_9011078_11	1121935.AQXX01000117_gene5104	7.498e-61	213.0	arCOG05193@1|root,2ZZSG@2|Bacteria,1REJB@1224|Proteobacteria,1SQYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9011078_7	292415.Tbd_2707	1.72e-90	303.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,1KT5D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
YHH2_k127_9011078_12	338966.Ppro_3609	1.324e-51	189.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,42W6Y@68525|delta/epsilon subdivisions,2WRWM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
YHH2_k127_9011078_0	395494.Galf_2216	0.0	1122.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,44W8T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
YHH2_k127_9011078_3	580332.Slit_1987	7.708e-153	490.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,44V6Z@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM glycine cleavage T protein (aminomethyl transferase)	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
YHH2_k127_9011078_5	580332.Slit_1988	1.012e-104	346.0	COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,2VRKF@28216|Betaproteobacteria,44VUS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cobalt uptake substrate-specific transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CbiM
YHH2_k127_9011078_14	1485544.JQKP01000013_gene1812	1.439e-41	157.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,44VYG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
YHH2_k127_9011078_9	580332.Slit_1990	4.732e-84	285.0	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,2VQT7@28216|Betaproteobacteria,44VUE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
YHH2_k127_9011078_10	580332.Slit_1991	2.928e-73	252.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,44VT1@713636|Nitrosomonadales	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
YHH2_k127_911955_0	580332.Slit_0441	8.648e-87	291.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,44V7U@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
YHH2_k127_911955_4	76114.ebD39	8.504e-21	94.0	COG4118@1|root,COG4118@2|Bacteria,1N7BG@1224|Proteobacteria,2VY0B@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_911955_1	1122604.JONR01000062_gene3114	4.036e-66	253.0	COG1404@1|root,COG1652@1|root,COG3209@1|root,COG1404@2|Bacteria,COG1652@2|Bacteria,COG3209@2|Bacteria,1R5VC@1224|Proteobacteria,1RR29@1236|Gammaproteobacteria,1X4RQ@135614|Xanthomonadales	135614|Xanthomonadales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,LysM,RHS_repeat
YHH2_k127_911955_2	1219375.CM002139_gene2196	7.011e-41	154.0	COG5573@1|root,COG5573@2|Bacteria,1N3BU@1224|Proteobacteria,1SY92@1236|Gammaproteobacteria,1XCRQ@135614|Xanthomonadales	135614|Xanthomonadales	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_912500_6	395494.Galf_1448	1.979e-78	270.0	COG2771@1|root,COG2771@2|Bacteria,1N6UR@1224|Proteobacteria,2WGVQ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K18304	ko02024,ko02025,map02024,map02025	M00644,M00769	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Autoind_bind,GerE
YHH2_k127_912500_14	395494.Galf_2202	2.911e-29	121.0	COG1918@1|root,COG1918@2|Bacteria,1NA6D@1224|Proteobacteria,2VY9N@28216|Betaproteobacteria,44W2B@713636|Nitrosomonadales	28216|Betaproteobacteria	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
YHH2_k127_912500_0	580332.Slit_2292	0.0	1043.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria,44VA4@713636|Nitrosomonadales	28216|Betaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
YHH2_k127_912500_13	243231.GSU0551	2.312e-36	142.0	COG4190@1|root,COG4190@2|Bacteria,1N3VQ@1224|Proteobacteria,42WRD@68525|delta/epsilon subdivisions,2WSHD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_912500_3	580332.Slit_2295	5.982e-112	365.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,44VNR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
YHH2_k127_912500_5	580332.Slit_2297	2.063e-80	269.0	COG0607@1|root,COG0607@2|Bacteria,1MZ87@1224|Proteobacteria,2W86M@28216|Betaproteobacteria,44WEQ@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH2_k127_912500_9	640081.Dsui_1368	3.013e-61	220.0	2CJ8Z@1|root,32WUG@2|Bacteria,1N1PS@1224|Proteobacteria,2VUYW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_912500_1	580332.Slit_2298	8.067e-252	780.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,44VEY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
YHH2_k127_912500_8	159087.Daro_3749	2.251e-61	219.0	COG4278@1|root,COG4278@2|Bacteria,1RBTS@1224|Proteobacteria,2VNXB@28216|Betaproteobacteria,2KY2A@206389|Rhodocyclales	206389|Rhodocyclales	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_912500_12	1485544.JQKP01000013_gene1836	2.833e-41	154.0	COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,2W5S7@28216|Betaproteobacteria,44WK1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
YHH2_k127_912500_2	580332.Slit_2299	5.635e-164	518.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,44V01@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
YHH2_k127_912500_7	580332.Slit_2301	1.031e-70	243.0	2DMT2@1|root,32TGY@2|Bacteria,1R3E1@1224|Proteobacteria,2VUA9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_912500_11	580332.Slit_2306	1.929e-50	192.0	2DRTJ@1|root,33CZM@2|Bacteria,1QF7V@1224|Proteobacteria,2VXR2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
YHH2_k127_912500_4	580332.Slit_2307	1.722e-83	285.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
YHH2_k127_913109_4	863239.AFIZ01000039_gene904	1.158e-23	102.0	2E3TC@1|root,32YQV@2|Bacteria,2GXYE@201174|Actinobacteria	201174|Actinobacteria	S	copG family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_913109_3	1112274.KI911560_gene257	3.194e-40	150.0	COG2929@1|root,COG2929@2|Bacteria,1MZKJ@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH2_k127_913109_5	585.DR95_1036	1.791e-13	78.0	2BHZK@1|root,32C45@2|Bacteria,1QCPV@1224|Proteobacteria,1T8FQ@1236|Gammaproteobacteria,3Z2T4@583|Proteus	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_913109_2	580332.Slit_0701	1.721e-58	204.0	2CU7M@1|root,32SUS@2|Bacteria,1N1WF@1224|Proteobacteria,2VUS0@28216|Betaproteobacteria,44VVW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
YHH2_k127_913109_1	395494.Galf_2273	3.245e-132	427.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2VK90@28216|Betaproteobacteria,44V07@713636|Nitrosomonadales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
YHH2_k127_913109_0	395494.Galf_2272	2.42e-219	683.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,44VG4@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	alcE	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
YHH2_k127_9223272_0	1121918.ARWE01000001_gene3196	1.338e-162	522.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43CY0@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
YHH2_k127_9223272_3	1121918.ARWE01000001_gene3197	2.994e-83	283.0	COG2204@1|root,COG4567@1|root,COG2204@2|Bacteria,COG4567@2|Bacteria	2|Bacteria	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	porX	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	PglZ,Response_reg
YHH2_k127_9223272_1	1121918.ARWE01000001_gene3198	2.837e-110	367.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43DFM@68525|delta/epsilon subdivisions,2X8MI@28221|Deltaproteobacteria,43UST@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YHH2_k127_9223272_2	1121918.ARWE01000001_gene3199	4.082e-96	338.0	COG2199@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
YHH2_k127_9223272_4	1249480.B649_09530	7.55e-33	134.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42VME@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
YHH2_k127_9235019_12	580332.Slit_2667	6.658e-30	121.0	COG1977@1|root,COG1977@2|Bacteria,1QDE3@1224|Proteobacteria,2W890@28216|Betaproteobacteria,44WKE@713636|Nitrosomonadales	28216|Betaproteobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
YHH2_k127_9235019_8	580332.Slit_2668	3.095e-83	279.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,44WFB@713636|Nitrosomonadales	28216|Betaproteobacteria	H	MoaC family	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
YHH2_k127_9235019_13	85643.Tmz1t_0393	7.11e-26	111.0	2AENS@1|root,314IU@2|Bacteria,1RINM@1224|Proteobacteria,2VTCG@28216|Betaproteobacteria,2KWJD@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9235019_7	748247.AZKH_p0058	4.427e-87	300.0	COG1143@1|root,COG1145@1|root,COG1143@2|Bacteria,COG1145@2|Bacteria,1QVIN@1224|Proteobacteria,2VI64@28216|Betaproteobacteria,2KVVD@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
YHH2_k127_9235019_14	76114.ebA6420	6.656e-14	78.0	COG0607@1|root,COG0607@2|Bacteria,1RHNV@1224|Proteobacteria,2VSK8@28216|Betaproteobacteria,2KWKY@206389|Rhodocyclales	206389|Rhodocyclales	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9235019_10	748247.AZKH_p0056	2.116e-46	175.0	COG0106@1|root,COG0106@2|Bacteria,1RF9S@1224|Proteobacteria,2VS3S@28216|Betaproteobacteria,2KWDH@206389|Rhodocyclales	206389|Rhodocyclales	E	Histidine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	His_biosynth
YHH2_k127_9235019_11	85643.Tmz1t_0389	8.806e-35	138.0	COG1547@1|root,COG1547@2|Bacteria,1RD2Q@1224|Proteobacteria,2VR6B@28216|Betaproteobacteria,2KWDS@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF309)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9235019_9	76114.ebA6425	9.71e-78	270.0	COG3381@1|root,COG3381@2|Bacteria,1R97V@1224|Proteobacteria,2VNS6@28216|Betaproteobacteria,2KVVK@206389|Rhodocyclales	206389|Rhodocyclales	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
YHH2_k127_9235019_0	748247.AZKH_p0053	0.0	1570.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,2KVC6@206389|Rhodocyclales	206389|Rhodocyclales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
YHH2_k127_9235019_6	85643.Tmz1t_0386	6.452e-91	307.0	COG3301@1|root,COG3301@2|Bacteria,1MXQ9@1224|Proteobacteria,2VJBF@28216|Betaproteobacteria,2KUPF@206389|Rhodocyclales	206389|Rhodocyclales	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
YHH2_k127_9235019_3	748247.AZKH_p0051	1.408e-123	400.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VK6R@28216|Betaproteobacteria,2KVYG@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4
YHH2_k127_9235019_1	580332.Slit_2669	6.407e-134	430.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,44UZK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
YHH2_k127_9235019_5	159087.Daro_2602	1.837e-102	342.0	COG3221@1|root,COG3221@2|Bacteria,1QJET@1224|Proteobacteria,2VIVQ@28216|Betaproteobacteria,2KUCY@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
YHH2_k127_9235019_4	713586.KB900536_gene937	3.094e-122	410.0	COG4191@1|root,COG4191@2|Bacteria,1QVHZ@1224|Proteobacteria,1S2DC@1236|Gammaproteobacteria,1WZY5@135613|Chromatiales	135613|Chromatiales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YHH2_k127_9235019_2	519989.ECTPHS_07147	3.718e-132	435.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1S1NC@1236|Gammaproteobacteria,1X06R@135613|Chromatiales	135613|Chromatiales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_923904_7	580332.Slit_0963	5e-106	347.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria,44V2R@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
YHH2_k127_923904_5	580332.Slit_0964	1.407e-136	441.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,44VQH@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
YHH2_k127_923904_0	1000565.METUNv1_01872	0.0	1179.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,2KUE7@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH2_k127_923904_12	580332.Slit_0966	6.718e-45	165.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2VSCU@28216|Betaproteobacteria,44VZ3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
YHH2_k127_923904_14	580332.Slit_0967	4.286e-37	141.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,44VZU@713636|Nitrosomonadales	28216|Betaproteobacteria	K	SMART Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
YHH2_k127_923904_2	580332.Slit_0721	1.489e-189	596.0	COG0842@1|root,COG0842@2|Bacteria,1PX28@1224|Proteobacteria,2VYZC@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
YHH2_k127_923904_3	580332.Slit_0722	6.334e-166	524.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,44VG9@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
YHH2_k127_923904_9	395494.Galf_1404	7.374e-58	202.0	2AY99@1|root,31QBJ@2|Bacteria,1RI92@1224|Proteobacteria,2VSPH@28216|Betaproteobacteria,44WGF@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_923904_15	580332.Slit_2773	8.379e-36	137.0	COG2345@1|root,COG2345@2|Bacteria,1N9W3@1224|Proteobacteria,2VWG0@28216|Betaproteobacteria,44WNR@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_923904_1	1000565.METUNv1_01579	5.609e-235	734.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,2KV7A@206389|Rhodocyclales	206389|Rhodocyclales	P	Chromate Ion Transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
YHH2_k127_923904_6	580332.Slit_1170	1.539e-123	400.0	COG4340@1|root,COG4340@2|Bacteria,1R9YQ@1224|Proteobacteria,2VHC5@28216|Betaproteobacteria,44WAY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	2OG-Fe dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-Fe_Oxy_2
YHH2_k127_923904_4	1198452.Jab_2c01100	9.514e-150	486.0	COG3344@1|root,COG3344@2|Bacteria,1R44F@1224|Proteobacteria,2VN79@28216|Betaproteobacteria,475VR@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	RVT_1
YHH2_k127_923904_10	1163617.SCD_n01447	2.699e-54	194.0	2AQ4B@1|root,31F9K@2|Bacteria,1N38C@1224|Proteobacteria,2VRH0@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_923904_11	395494.Galf_2486	2.945e-45	171.0	COG3909@1|root,COG3909@2|Bacteria,1N1X2@1224|Proteobacteria,2WFRJ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C'	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
YHH2_k127_923904_8	580332.Slit_1136	2.982e-103	339.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VMVD@28216|Betaproteobacteria,44W52@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
YHH2_k127_923904_13	580332.Slit_1135	8.061e-39	145.0	COG1136@1|root,COG1136@2|Bacteria,1MXVW@1224|Proteobacteria,2VI95@28216|Betaproteobacteria,44W8E@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_9279517_1	580332.Slit_2131	6.289e-182	571.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,44VAH@713636|Nitrosomonadales	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH2_k127_9279517_0	580332.Slit_0842	9.382e-239	751.0	COG4783@1|root,COG4783@2|Bacteria,1QTUQ@1224|Proteobacteria	1224|Proteobacteria	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD
YHH2_k127_9279517_2	1123393.KB891332_gene2682	3.45e-64	232.0	COG0457@1|root,COG0457@2|Bacteria,1QYB9@1224|Proteobacteria	1224|Proteobacteria	M	Tetratricopeptide repeat	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2
YHH2_k127_9279517_3	1123393.KB891332_gene2683	2.579e-12	67.0	COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,2VPPW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_2,VWA_2
YHH2_k127_9315382_2	580332.Slit_1709	5.121e-10	64.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria,44WEC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
YHH2_k127_9315382_1	580332.Slit_1710	4.645e-160	505.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,44W9R@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S binding domain	-	-	-	ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4
YHH2_k127_9315382_0	580332.Slit_1711	0.0	1012.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,44WAX@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YHH2_k127_9324972_0	580332.Slit_2505	8.41e-133	427.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,44V9E@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
YHH2_k127_9324972_2	1485544.JQKP01000001_gene1292	9.975e-94	319.0	COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,2WGFH@28216|Betaproteobacteria,44WPI@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
YHH2_k127_9324972_3	580332.Slit_0701	3.71e-56	205.0	2CU7M@1|root,32SUS@2|Bacteria,1N1WF@1224|Proteobacteria,2VUS0@28216|Betaproteobacteria,44VVW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
YHH2_k127_9324972_1	580332.Slit_0702	6.085e-126	408.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2VK90@28216|Betaproteobacteria,44V07@713636|Nitrosomonadales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
YHH2_k127_9358519_1	1331060.RLDS_11260	5.574e-18	83.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9358519_0	1183438.GKIL_3505	1.359e-130	442.0	COG1506@1|root,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria	1117|Cyanobacteria	EU	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YHH2_k127_9417629_4	580332.Slit_1357	1.679e-29	117.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,44W8Q@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
YHH2_k127_9417629_5	580332.Slit_1357	3.672e-10	62.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,44W8Q@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
YHH2_k127_9417629_0	580332.Slit_1358	4.213e-262	809.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,44WHF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
YHH2_k127_9417629_1	580332.Slit_1359	7.127e-148	471.0	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,2VH72@28216|Betaproteobacteria,44WBY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH2_k127_9417629_3	580332.Slit_1360	1.526e-61	217.0	COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2VRBU@28216|Betaproteobacteria,44VTZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
YHH2_k127_9417629_2	580332.Slit_1361	3.347e-121	391.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2VH1C@28216|Betaproteobacteria,44VKH@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
YHH2_k127_9452260_6	765911.Thivi_2490	5.049e-08	54.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1WXZW@135613|Chromatiales	135613|Chromatiales	L	PFAM integrase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
YHH2_k127_9452260_2	330214.NIDE3427	1.129e-71	254.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
YHH2_k127_9452260_1	1122137.AQXF01000005_gene1372	2.365e-229	743.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1MVIM@1224|Proteobacteria,2TR88@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2
YHH2_k127_9452260_5	1211777.BN77_p11450	1.693e-08	68.0	COG0438@1|root,COG0438@2|Bacteria,1R1HT@1224|Proteobacteria,2TZ2D@28211|Alphaproteobacteria,4BB2Z@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9452260_0	631362.Thi970DRAFT_02857	1.754e-306	962.0	COG0438@1|root,COG1216@1|root,COG3551@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG3551@2|Bacteria,1QP7Y@1224|Proteobacteria,1RR12@1236|Gammaproteobacteria,1WXJ8@135613|Chromatiales	135613|Chromatiales	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2
YHH2_k127_9452260_4	399795.CtesDRAFT_PD1865	7.315e-55	196.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VJBU@28216|Betaproteobacteria,4AFRQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Polysaccharide biosynthesis/export protein	kpsD	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
YHH2_k127_9478124_0	1266925.JHVX01000009_gene31	8.501e-156	511.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,2VHW1@28216|Betaproteobacteria,372KY@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Surface antigen	tama	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
YHH2_k127_9489985_4	580332.Slit_1329	2.547e-75	255.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WGQ0@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
YHH2_k127_9489985_1	580332.Slit_1330	5.504e-171	548.0	COG0745@1|root,COG2206@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2206@2|Bacteria,COG3829@2|Bacteria,1RAQS@1224|Proteobacteria,2VQE0@28216|Betaproteobacteria,44WFJ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,PAS_4
YHH2_k127_9489985_3	580332.Slit_0098	2.549e-90	303.0	COG0457@1|root,COG0457@2|Bacteria,1R85G@1224|Proteobacteria,2W1NE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9489985_0	580332.Slit_1331	6.321e-279	860.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,44VI7@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
YHH2_k127_9489985_2	1298593.TOL_2818	3.428e-101	354.0	COG1629@1|root,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,1SZT1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
YHH2_k127_9503004_6	580332.Slit_2555	2.081e-27	111.0	COG0636@1|root,COG0636@2|Bacteria,1REA9@1224|Proteobacteria,2W4JN@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
YHH2_k127_9503004_5	580332.Slit_2554	1.726e-46	169.0	COG1436@1|root,COG1436@2|Bacteria,1MZUE@1224|Proteobacteria,2W5EY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase (F/14-kDa) subunit	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_F
YHH2_k127_9503004_3	580332.Slit_2553	2.975e-51	190.0	COG1390@1|root,COG1390@2|Bacteria,1R8BT@1224|Proteobacteria,2W49R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	V-type proton ATPase subunit E	-	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
YHH2_k127_9503004_0	580332.Slit_2552	0.0	1009.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,2W0G7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
YHH2_k127_9503004_4	580332.Slit_0180	1.699e-47	180.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,2VWIX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
YHH2_k127_9503004_1	580332.Slit_2551	2.063e-269	832.0	COG1156@1|root,COG1156@2|Bacteria,1QUQE@1224|Proteobacteria	1224|Proteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab
YHH2_k127_9503004_2	580332.Slit_2550	5.219e-102	338.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,2W26X@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase subunit D	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
YHH2_k127_9515946_4	1120999.JONM01000007_gene1869	1.532e-41	158.0	COG3744@1|root,COG3744@2|Bacteria,1RJ4K@1224|Proteobacteria,2VTJR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_9515946_6	667632.KB890220_gene2732	4.137e-26	109.0	COG4118@1|root,COG4118@2|Bacteria,1NAEH@1224|Proteobacteria,2VWR1@28216|Betaproteobacteria,1KA36@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_9515946_5	1235457.C404_22625	7.299e-27	116.0	29XYS@1|root,314YN@2|Bacteria,1PUX2@1224|Proteobacteria,2WAZA@28216|Betaproteobacteria,1KF4K@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9515946_3	857087.Metme_2410	1.598e-77	266.0	COG1842@1|root,COG1842@2|Bacteria,1NB0D@1224|Proteobacteria	1224|Proteobacteria	KT	PspA IM30 family protein	MA20_29850	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
YHH2_k127_9515946_2	857087.Metme_2411	2.75e-78	268.0	COG1585@1|root,COG1585@2|Bacteria,1RG29@1224|Proteobacteria,1S7HI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OU	Protein of unknown function (DUF1449)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449
YHH2_k127_9515946_0	857087.Metme_2412	1.8e-267	831.0	COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,1RRHJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yqiK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
YHH2_k127_9515946_1	1005048.CFU_4245	6.079e-99	332.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2VH7Q@28216|Betaproteobacteria,4765Q@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	creC	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_3
YHH2_k127_9520005_2	1095769.CAHF01000008_gene3647	1.121e-140	452.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2VHDA@28216|Betaproteobacteria,475YV@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Cation efflux family	czcD	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
YHH2_k127_9520005_12	1173028.ANKO01000020_gene5475	1.148e-36	141.0	COG4634@1|root,COG4634@2|Bacteria,1GA03@1117|Cyanobacteria,1HDVT@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9520005_16	1173023.KE650771_gene588	3.513e-17	88.0	COG2442@1|root,COG2442@2|Bacteria,1G9FC@1117|Cyanobacteria,1JMBK@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YHH2_k127_9520005_10	314345.SPV1_05148	2.301e-47	174.0	COG3791@1|root,COG3791@2|Bacteria	2|Bacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
YHH2_k127_9520005_7	743299.Acife_1472	4.356e-70	241.0	2DNPN@1|root,32YG3@2|Bacteria,1N9YB@1224|Proteobacteria,1SE1E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
YHH2_k127_9520005_13	1123399.AQVE01000068_gene1053	2.457e-32	129.0	2DTAR@1|root,33JFR@2|Bacteria,1P86J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9520005_11	580332.Slit_1564	1.516e-41	156.0	2C9QX@1|root,316K7@2|Bacteria,1PXQK@1224|Proteobacteria,2VWP4@28216|Betaproteobacteria	580332.Slit_1564|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9520005_14	1163617.SCD_n00228	3.37e-32	129.0	295X6@1|root,2ZT81@2|Bacteria,1PBJJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	-
YHH2_k127_9520005_5	1163617.SCD_n00227	2.594e-109	361.0	COG1366@1|root,COG1366@2|Bacteria,1MVPW@1224|Proteobacteria,2VNVR@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	rsbRA	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	Protoglobin,RsbRD_N,STAS
YHH2_k127_9520005_4	1163617.SCD_n00226	2.49e-123	406.0	COG2172@1|root,COG2172@2|Bacteria,1RD6C@1224|Proteobacteria,2VQE3@28216|Betaproteobacteria	28216|Betaproteobacteria	T	anti-sigma regulatory factor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE
YHH2_k127_9520005_9	1269813.ATUL01000029_gene1302	1.963e-50	192.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE1,PAS_4,PAS_9,Response_reg,TPR_12
YHH2_k127_9520005_0	580332.Slit_0830	3.834e-218	682.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VHHK@28216|Betaproteobacteria,44WDH@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM UMUC domain protein DNA-repair protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
YHH2_k127_9520005_6	580332.Slit_1366	6.7e-97	320.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,44V9Z@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH2_k127_9520005_8	580332.Slit_1365	7.372e-59	207.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,44VVS@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH2_k127_9520005_1	580332.Slit_1364	9.352e-162	514.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,44UYT@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
YHH2_k127_9520005_15	580332.Slit_1363	4.483e-24	108.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,44W2Q@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Trm112p-like protein	ycaR	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
YHH2_k127_9520005_3	580332.Slit_1362	8.218e-136	436.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,44VH9@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
YHH2_k127_9578124_9	1163617.SCD_n00381	3.165e-46	173.0	COG2863@1|root,COG2863@2|Bacteria,1R8K9@1224|Proteobacteria	1224|Proteobacteria	C	Pfam cytochrome c	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C,Cytochrome_CBB3
YHH2_k127_9578124_1	1163617.SCD_n00382	1.073e-161	520.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	soxF	-	1.8.2.3,1.8.5.4	ko:K17218,ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499,R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DUF442,FCSD-flav_bind,Pyr_redox_2
YHH2_k127_9578124_3	580332.Slit_1695	9.932e-156	503.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YHH2_k127_9578124_11	580332.Slit_1707	1.76e-32	127.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,44WMA@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Sulfurtransferase TusA	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
YHH2_k127_9578124_5	580332.Slit_1706	1.439e-89	296.0	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,2VS0Z@28216|Betaproteobacteria,44WBW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
YHH2_k127_9578124_0	1485544.JQKP01000015_gene2090	1.518e-189	603.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2WD6M@28216|Betaproteobacteria,44WJD@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
YHH2_k127_9578124_2	580332.Slit_1692	7.034e-156	495.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria,44W7U@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
YHH2_k127_9578124_4	580332.Slit_1691	2.259e-98	323.0	28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,2VUGA@28216|Betaproteobacteria,44W4S@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9578124_6	580332.Slit_1690	2.739e-84	282.0	COG0425@1|root,COG0425@2|Bacteria,1PX23@1224|Proteobacteria,2WCJT@28216|Betaproteobacteria,44W8S@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
YHH2_k127_9578124_8	580332.Slit_1689	7.451e-55	194.0	COG2920@1|root,COG2920@2|Bacteria,1N2HP@1224|Proteobacteria,2VVGF@28216|Betaproteobacteria,44WH7@713636|Nitrosomonadales	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
YHH2_k127_9578124_7	580332.Slit_1688	1.024e-72	250.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,2VVIY@28216|Betaproteobacteria,44WHH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cas6 Crispr	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
YHH2_k127_9578124_12	580332.Slit_1687	5.466e-29	117.0	2EMP6@1|root,33FBM@2|Bacteria,1NGBE@1224|Proteobacteria,2VYCB@28216|Betaproteobacteria,44WK7@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9578124_10	580332.Slit_1686	4.26e-38	146.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,2VPWJ@28216|Betaproteobacteria,44W8G@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
YHH2_k127_9582855_1	1123368.AUIS01000029_gene1282	8.909e-100	331.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,2NBXD@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
YHH2_k127_9582855_0	582744.Msip34_2332	3.971e-107	353.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,2KKRZ@206350|Nitrosomonadales	206350|Nitrosomonadales	H	PFAM MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
YHH2_k127_9584695_0	580332.Slit_0333	0.0	2164.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,44VCD@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Domain of unknown function (DUF3400)	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
YHH2_k127_9584695_1	580332.Slit_0332	6.888e-166	537.0	2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria,44W4N@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9584695_2	1151116.Q7S_01055	4.576e-106	348.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RNYG@1236|Gammaproteobacteria,3FHRT@34037|Rahnella	1236|Gammaproteobacteria	S	HipA-like C-terminal domain	hipA	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
YHH2_k127_9596580_0	1217648.F933_02573	1.656e-222	698.0	COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,3NJP9@468|Moraxellaceae	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	calB	-	1.2.1.68	ko:K00154	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
YHH2_k127_9596580_1	580332.Slit_0300	1.257e-75	256.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2VSGQ@28216|Betaproteobacteria,44VSW@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH2_k127_9628709_2	580332.Slit_2312	1.553e-112	368.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2VI2Y@28216|Betaproteobacteria,44VPI@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1,3.1.11.6	ko:K03601,ko:K04564	ko03430,ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map03430,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Sod_Fe_C,Sod_Fe_N
YHH2_k127_9628709_0	580332.Slit_2313	1.314e-187	589.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,44VKS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
YHH2_k127_9628709_3	62928.azo1372	4.088e-08	55.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KV9Z@206389|Rhodocyclales	206389|Rhodocyclales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_9628709_1	1163617.SCD_n00731	8.96e-118	384.0	COG0457@1|root,COG0457@2|Bacteria,1QV5B@1224|Proteobacteria,2WGRP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16
YHH2_k127_9657129_12	1331060.RLDS_11260	5.574e-18	83.0	COG1846@1|root,COG3335@1|root,COG1846@2|Bacteria,COG3335@2|Bacteria,1PPR9@1224|Proteobacteria,2UZYY@28211|Alphaproteobacteria,2KBY5@204457|Sphingomonadales	204457|Sphingomonadales	K	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9657129_14	378806.STAUR_0345	2.11e-15	89.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria,2YX17@29|Myxococcales	28221|Deltaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,Kelch_1,Kelch_4
YHH2_k127_9657129_11	1121918.ARWE01000001_gene3170	2.958e-35	150.0	COG1520@1|root,COG4886@1|root,COG1520@2|Bacteria,COG4886@2|Bacteria,1PIDG@1224|Proteobacteria,42UM6@68525|delta/epsilon subdivisions,2WPZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
YHH2_k127_9657129_6	1175306.GWL_02640	1.44e-58	205.0	COG2320@1|root,COG2320@2|Bacteria,1N3ZU@1224|Proteobacteria,2VUDF@28216|Betaproteobacteria,47566@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9657129_15	292563.Cyast_0013	1.448e-09	60.0	2E3EN@1|root,32YDN@2|Bacteria,1G85N@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
YHH2_k127_9657129_13	637389.Acaty_c1720	5.736e-17	87.0	28SSJ@1|root,2ZF2C@2|Bacteria,1RBGE@1224|Proteobacteria,1S8RP@1236|Gammaproteobacteria,2NCY8@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
YHH2_k127_9657129_9	316067.Geob_3253	1.966e-44	185.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YHH2_k127_9657129_17	1124780.ANNU01000008_gene2681	7.193e-06	59.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Big_3_5,DUF2637,He_PIG,TIG
YHH2_k127_9657129_10	1286631.X805_02730	2.158e-44	169.0	COG2197@1|root,COG2197@2|Bacteria,1RGXD@1224|Proteobacteria,2WEGP@28216|Betaproteobacteria,1KIYQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_9657129_5	580332.Slit_0952	7.252e-68	231.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,2VSDU@28216|Betaproteobacteria,44VUZ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
YHH2_k127_9657129_2	580332.Slit_0951	2.222e-134	438.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2VHF1@28216|Betaproteobacteria,44V75@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
YHH2_k127_9657129_7	305700.B447_15261	3.291e-56	207.0	2BCPH@1|root,3269T@2|Bacteria,1RJN1@1224|Proteobacteria,2W2DM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4824)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4824
YHH2_k127_9657129_3	522306.CAP2UW1_2222	2.193e-131	428.0	28IWG@1|root,2Z8US@2|Bacteria,1NHDW@1224|Proteobacteria,2VPYM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
YHH2_k127_9657129_0	62928.azo0005	7.663e-161	520.0	COG2865@1|root,COG2865@2|Bacteria,1R4MD@1224|Proteobacteria,2VK3T@28216|Betaproteobacteria,2KXMI@206389|Rhodocyclales	206389|Rhodocyclales	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
YHH2_k127_9657129_1	580332.Slit_0950	3e-139	447.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2VHZ0@28216|Betaproteobacteria,44V0C@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
YHH2_k127_9657129_4	580332.Slit_0949	7.613e-121	389.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,2VQ8U@28216|Betaproteobacteria,44W91@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
YHH2_k127_9657129_8	580332.Slit_0948	9.433e-55	193.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,44VXI@713636|Nitrosomonadales	28216|Betaproteobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
YHH2_k127_9732967_5	83406.HDN1F_18580	5.345e-42	154.0	COG4691@1|root,COG4691@2|Bacteria,1N8BI@1224|Proteobacteria,1SDUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	-
YHH2_k127_9732967_3	83406.HDN1F_18590	1.276e-69	237.0	COG1487@1|root,COG1487@2|Bacteria,1MZQC@1224|Proteobacteria,1SAJG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
YHH2_k127_9732967_2	580332.Slit_2794	4e-73	247.0	COG5499@1|root,COG5499@2|Bacteria,1N89F@1224|Proteobacteria,2VWB3@28216|Betaproteobacteria,44WNE@713636|Nitrosomonadales	28216|Betaproteobacteria	K	SMART helix-turn-helix domain protein	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
YHH2_k127_9732967_4	580332.Slit_2793	3.634e-56	196.0	COG4680@1|root,COG4680@2|Bacteria,1N8JN@1224|Proteobacteria,2WAJH@28216|Betaproteobacteria,44WP0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
YHH2_k127_9732967_1	580332.Slit_1509	3.678e-113	369.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,44VPU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
YHH2_k127_9732967_0	580332.Slit_1510	3.194e-130	421.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,44VMR@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH2_k127_9809098_0	1123401.JHYQ01000051_gene473	2.068e-200	631.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria,46386@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
YHH2_k127_9809098_1	358220.C380_06710	1.049e-155	516.0	COG4585@1|root,COG4585@2|Bacteria,1R8DN@1224|Proteobacteria,2VPJ9@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
YHH2_k127_9809098_2	1538295.JY96_09795	1.375e-62	222.0	COG2197@1|root,COG2197@2|Bacteria,1RGXD@1224|Proteobacteria,2WEGP@28216|Betaproteobacteria,1KIYQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_9812395_3	580332.Slit_1180	1.677e-118	382.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,44VK1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
YHH2_k127_9812395_0	580332.Slit_1811	0.0	1319.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2VGZZ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
YHH2_k127_9812395_1	1303518.CCALI_00158	3.293e-237	744.0	COG0166@1|root,COG0166@2|Bacteria	2|Bacteria	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcSMS35_1347.EcSMS35_4486	PGI
YHH2_k127_9812395_2	580332.Slit_1809	4.714e-216	676.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,44V0E@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
YHH2_k127_9838897_13	580332.Slit_1024	1.81e-08	55.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,44VA2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH2_k127_9838897_3	395494.Galf_1991	2.152e-192	601.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,44VFG@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YHH2_k127_9838897_1	580332.Slit_1022	8.21e-262	808.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,44V8H@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
YHH2_k127_9838897_6	580332.Slit_1021	1.221e-95	314.0	COG2110@1|root,COG2110@2|Bacteria,1MVYN@1224|Proteobacteria,2VH7H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Appr-1-p processing	-	-	-	-	-	-	-	-	-	-	-	-	Macro
YHH2_k127_9838897_11	580332.Slit_1020	9.635e-46	168.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,2VSCI@28216|Betaproteobacteria,44W28@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
YHH2_k127_9838897_7	580332.Slit_1019	5.579e-91	300.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,44VS5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF520)	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
YHH2_k127_9838897_5	580332.Slit_1018	4.229e-110	362.0	COG0671@1|root,COG0671@2|Bacteria,1PSM7@1224|Proteobacteria,2WB4I@28216|Betaproteobacteria,44WMP@713636|Nitrosomonadales	28216|Betaproteobacteria	I	SMART phosphoesterase PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YHH2_k127_9838897_8	580332.Slit_1017	7.351e-90	299.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,44VU8@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
YHH2_k127_9838897_9	580332.Slit_1011	2.357e-66	226.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,44VWK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YHH2_k127_9838897_0	580332.Slit_1010	3.756e-265	818.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2VJ2E@28216|Betaproteobacteria,44VCZ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
YHH2_k127_9838897_10	580332.Slit_1009	7.129e-57	199.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2VSHZ@28216|Betaproteobacteria,44VX7@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
YHH2_k127_9838897_12	580332.Slit_1008	1.246e-44	162.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,44VZX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YHH2_k127_9838897_2	580332.Slit_1007	1.769e-218	679.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria,44VGK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
YHH2_k127_9838897_4	580332.Slit_1006	1.226e-120	389.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,44UZW@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
YHH2_k127_9839845_0	580332.Slit_2746	0.0	1154.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,44VDQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YHH2_k127_9839845_4	395494.Galf_2669	1.477e-65	229.0	COG0212@1|root,COG0212@2|Bacteria,1PWVW@1224|Proteobacteria,2WCEJ@28216|Betaproteobacteria,44VWT@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
YHH2_k127_9839845_1	946483.Cenrod_1276	2.815e-295	915.0	COG1106@1|root,COG1106@2|Bacteria,1R43N@1224|Proteobacteria,2VPY5@28216|Betaproteobacteria,4ADDV@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
YHH2_k127_9839845_3	1120999.JONM01000009_gene396	8.9e-72	244.0	COG2445@1|root,COG2445@2|Bacteria,1RD67@1224|Proteobacteria,2VRFC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
YHH2_k127_9839845_5	340177.Cag_0331	7.628e-07	57.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF86,NTP_transf_2
YHH2_k127_9839845_2	580332.Slit_2743	6.571e-73	246.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,44UZX@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
YHH2_k127_9841428_0	927677.ALVU02000006_gene425	9.034e-121	404.0	COG4467@1|root,COG4467@2|Bacteria,1GR8D@1117|Cyanobacteria	1117|Cyanobacteria	S	Involved in initiation control of chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9929199_2	580332.Slit_1850	4.189e-235	730.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,44VHW@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Thiolase, C-terminal domain	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
YHH2_k127_9929199_19	580332.Slit_1849	8.657e-65	226.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria,44W0B@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
YHH2_k127_9929199_6	580332.Slit_1848	1.952e-185	587.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,2VISX@28216|Betaproteobacteria,44V9V@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9929199_7	580332.Slit_1847	1.313e-183	586.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,44WAK@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K07814,ko:K13815	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HD,HD_5,Response_reg
YHH2_k127_9929199_3	580332.Slit_1846	2.455e-215	672.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VINV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Radical SAM	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
YHH2_k127_9929199_18	292415.Tbd_1586	4.375e-66	232.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,1KS3P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
YHH2_k127_9929199_11	580332.Slit_1844	3.493e-124	402.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,44W5F@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
YHH2_k127_9929199_20	395494.Galf_0346	9.997e-56	199.0	COG0664@1|root,COG0664@2|Bacteria,1NBRS@1224|Proteobacteria,2WCFJ@28216|Betaproteobacteria,44VZA@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
YHH2_k127_9929199_8	765912.Thimo_0240	1.459e-151	486.0	COG2301@1|root,COG2301@2|Bacteria,1QDT5@1224|Proteobacteria,1RQI7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
YHH2_k127_9929199_15	1049564.TevJSym_az00340	2.189e-101	336.0	COG1018@1|root,COG1152@1|root,COG1018@2|Bacteria,COG1152@2|Bacteria,1R9TR@1224|Proteobacteria,1SJQC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_9
YHH2_k127_9929199_1	1049564.TevJSym_az00330	1.895e-273	850.0	COG1053@1|root,COG1053@2|Bacteria,1R478@1224|Proteobacteria	1224|Proteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
YHH2_k127_9929199_24	765912.Thimo_0258	1.439e-29	128.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YHH2_k127_9929199_22	765912.Thimo_0247	2.257e-44	166.0	COG1150@1|root,COG1150@2|Bacteria,1R874@1224|Proteobacteria,1SHQ0@1236|Gammaproteobacteria,1WZZ0@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
YHH2_k127_9929199_14	765912.Thimo_0248	1.485e-111	367.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,1SBBX@1236|Gammaproteobacteria,1X060@135613|Chromatiales	135613|Chromatiales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
YHH2_k127_9929199_23	1049564.TevJSym_az00300	9.574e-31	124.0	COG1146@1|root,COG1146@2|Bacteria,1N0QV@1224|Proteobacteria,1SQ9V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	-
YHH2_k127_9929199_5	765912.Thimo_0250	1.432e-189	598.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1WXU8@135613|Chromatiales	135613|Chromatiales	C	oxidoreductase, alpha subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N,Transketolase_C
YHH2_k127_9929199_9	1049564.TevJSym_az00280	1.829e-147	478.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
YHH2_k127_9929199_16	1049564.TevJSym_az00270	7.775e-77	261.0	COG1014@1|root,COG1014@2|Bacteria,1RAA8@1224|Proteobacteria,1SK9E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
YHH2_k127_9929199_0	1049564.TevJSym_az00260	0.0	1047.0	COG1148@1|root,COG1148@2|Bacteria,1R882@1224|Proteobacteria,1SAD3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
YHH2_k127_9929199_17	765912.Thimo_0254	1.425e-67	232.0	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,1SPUH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
YHH2_k127_9929199_13	1049564.TevJSym_az00230	2.594e-122	401.0	COG1035@1|root,COG4656@1|root,COG1035@2|Bacteria,COG4656@2|Bacteria,1NQN7@1224|Proteobacteria,1SM0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus	-	-	-	-	-	-	-	-	-	-	-	-	FrhB_FdhB_C
YHH2_k127_9929199_12	765912.Thimo_0256	9.688e-124	406.0	COG0479@1|root,COG0479@2|Bacteria,1QVWG@1224|Proteobacteria,1RNMQ@1236|Gammaproteobacteria,1WYUM@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
YHH2_k127_9929199_10	765912.Thimo_0257	1.25e-131	424.0	COG0543@1|root,COG0543@2|Bacteria,1MV72@1224|Proteobacteria,1T4D8@1236|Gammaproteobacteria,1X2TA@135613|Chromatiales	135613|Chromatiales	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
YHH2_k127_9929199_4	305700.B447_02566	4.795e-213	667.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,2VZNI@28216|Betaproteobacteria,2KYE8@206389|Rhodocyclales	206389|Rhodocyclales	C	ATP citrate lyase citrate-binding	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2,Citrate_bind
YHH2_k127_9929199_21	460265.Mnod_2762	1.807e-54	192.0	COG0074@1|root,COG0074@2|Bacteria,1R4KP@1224|Proteobacteria,2TVFC@28211|Alphaproteobacteria,1JX4X@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Succ_CoA_lig
YHH2_k127_998629_0	543913.D521_1217	3.563e-318	1000.0	COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,2VMKD@28216|Betaproteobacteria	28216|Betaproteobacteria	V	type II restriction enzyme, methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
YHH2_k127_998629_1	261292.Nit79A3_2000	2.05e-65	235.0	2DBHN@1|root,2Z9BF@2|Bacteria,1QWQ3@1224|Proteobacteria,2VH4F@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 3491 queries scanned
## Total time (seconds): 6.153473854064941
## Rate: 567.32 q/s
