## Fri Feb 20 05:52:53 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/YHH2_bin.33.fa -m mmseqs --output YHH2_bin.33 --output_dir /data/result/bins/wyx/eggqs50+/YHH2_bin.33 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YHH2_k127_10014952_0	1210884.HG799469_gene14157	6.382e-280	871.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
YHH2_k127_10014952_1	1396141.BATP01000007_gene5629	4.599e-97	332.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH2_k127_10014952_2	234267.Acid_2416	4.721e-26	118.0	COG4287@1|root,COG4287@2|Bacteria	2|Bacteria	S	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
YHH2_k127_10068300_0	1410630.JNKP01000003_gene1590	1.748e-53	196.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,27IHB@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
YHH2_k127_10068300_3	452637.Oter_0732	4.546e-11	74.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	DUF2510,FHA,RDD
YHH2_k127_10068300_1	880072.Desac_2421	1.292e-30	133.0	COG5523@1|root,COG5523@2|Bacteria,1RGXF@1224|Proteobacteria,42WIC@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
YHH2_k127_10068300_2	543632.JOJL01000014_gene9133	7.788e-14	81.0	COG4733@1|root,COG4733@2|Bacteria,2GK1U@201174|Actinobacteria,4DBS1@85008|Micromonosporales	201174|Actinobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH2_k127_10111864_1	452637.Oter_1547	9.579e-49	179.0	COG3808@1|root,COG3808@2|Bacteria,46S7R@74201|Verrucomicrobia,3K82Q@414999|Opitutae	414999|Opitutae	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
YHH2_k127_10111864_2	926566.Terro_1765	6.59e-28	130.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,DUF1565,Glyco_hydro_10
YHH2_k127_10111864_4	404589.Anae109_2051	6.465e-07	63.0	COG3055@1|root,COG4412@1|root,COG3055@2|Bacteria,COG4412@2|Bacteria,1MWWV@1224|Proteobacteria	1224|Proteobacteria	O	Zinc metalloprotease (Elastase)	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
YHH2_k127_10111864_3	864051.BurJ1DRAFT_0891	2.276e-20	107.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R1VH@1224|Proteobacteria,2WI5Y@28216|Betaproteobacteria,1KP12@119065|unclassified Burkholderiales	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,RCC1,RCC1_2,WD40
YHH2_k127_10111864_0	880526.KE386488_gene1576	1.478e-93	338.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10112820_4	497964.CfE428DRAFT_2387	9.886e-98	328.0	COG0491@1|root,COG0491@2|Bacteria,46S7X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH2_k127_10112820_2	497964.CfE428DRAFT_2386	7.888e-120	394.0	COG2084@1|root,COG2084@2|Bacteria,46S95@74201|Verrucomicrobia	74201|Verrucomicrobia	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
YHH2_k127_10112820_1	452637.Oter_2162	6.89e-133	435.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
YHH2_k127_10112820_0	452637.Oter_2161	2.149e-154	494.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
YHH2_k127_10112820_3	1185876.BN8_06038	5.464e-101	338.0	COG1082@1|root,COG1082@2|Bacteria,4NGKX@976|Bacteroidetes,47JP9@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_10112820_7	1396141.BATP01000030_gene3637	1.528e-08	68.0	COG2133@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3828@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,ThuA
YHH2_k127_10112820_5	497964.CfE428DRAFT_4431	3.269e-40	171.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3227@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	CHU_C,FTP,PQQ_2,Peptidase_M36
YHH2_k127_10112820_6	203124.Tery_0599	1.699e-31	143.0	COG1572@1|root,COG3391@1|root,COG1572@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
YHH2_k127_10130423_2	886293.Sinac_6951	1.752e-14	76.0	COG2010@1|root,COG2010@2|Bacteria,2IXJ6@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
YHH2_k127_10130423_0	314230.DSM3645_06756	7.817e-216	679.0	COG4102@1|root,COG4102@2|Bacteria,2J4YY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH2_k127_10130423_3	1123504.JQKD01000035_gene2646	3.712e-10	69.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,4ABFG@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM VanZ family protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
YHH2_k127_10130423_1	530564.Psta_1926	4.316e-147	477.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_10131357_0	575540.Isop_1893	8.005e-218	700.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IYBE@203682|Planctomycetes	203682|Planctomycetes	EU	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
YHH2_k127_10169328_6	936053.I1BU69	1.284e-08	57.0	COG5147@1|root,KOG0048@2759|Eukaryota,38EUR@33154|Opisthokonta,3P4KQ@4751|Fungi,1GVZA@112252|Fungi incertae sedis	4751|Fungi	K	Myb-like DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Myb_DNA-binding
YHH2_k127_10169328_5	1121396.KB892901_gene2171	1.221e-39	158.0	COG1409@1|root,COG3291@1|root,COG4733@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,1QZGY@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,DUF839,Exo_endo_phos,PKD
YHH2_k127_10169328_0	794903.OPIT5_28170	4.755e-205	651.0	COG0519@1|root,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	414999|Opitutae	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
YHH2_k127_10169328_1	1182590.BN5_03807	1.001e-120	404.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATPase, AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH2_k127_10169328_4	452637.Oter_0347	4.513e-42	161.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C
YHH2_k127_10169328_2	452637.Oter_1277	3.253e-73	258.0	COG4191@1|root,COG4191@2|Bacteria,46Z7N@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
YHH2_k127_10169328_3	452637.Oter_1278	7.5e-68	241.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,3K7NF@414999|Opitutae	74201|Verrucomicrobia	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_10194114_1	452637.Oter_0650	5.351e-09	64.0	COG4726@1|root,COG4726@2|Bacteria,46YMK@74201|Verrucomicrobia,3K9UG@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10194114_3	267608.RSc0726	0.0001798	53.0	COG4966@1|root,COG4966@2|Bacteria,1R5TH@1224|Proteobacteria,2VVQG@28216|Betaproteobacteria,1K1TH@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	type iv pilus assembly protein	pilW	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
YHH2_k127_10194114_0	378806.STAUR_7504	1.449e-76	281.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,1QUYA@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
YHH2_k127_10233511_2	1125863.JAFN01000001_gene970	6.848e-82	281.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YHH2_k127_10233511_6	391008.Smal_2239	1.725e-16	90.0	COG0746@1|root,COG0746@2|Bacteria,1NAYX@1224|Proteobacteria,1SCS5@1236|Gammaproteobacteria,1XCJG@135614|Xanthomonadales	135614|Xanthomonadales	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	-	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
YHH2_k127_10233511_0	886293.Sinac_6514	5.043e-86	295.0	COG0265@1|root,COG0265@2|Bacteria,2IYNW@203682|Planctomycetes	203682|Planctomycetes	O	C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
YHH2_k127_10233511_7	595460.RRSWK_03064	2.454e-08	67.0	291K2@1|root,2ZP6D@2|Bacteria,2IZ9X@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
YHH2_k127_10233511_3	765911.Thivi_1527	1.103e-70	246.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,1RS1G@1236|Gammaproteobacteria,1WXVJ@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YHH2_k127_10233511_5	1172190.M947_07150	8.634e-43	168.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42QDE@68525|delta/epsilon subdivisions,2YMPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YHH2_k127_10233511_4	497964.CfE428DRAFT_4864	7.303e-58	209.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10233511_1	886293.Sinac_6489	8.178e-85	290.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
YHH2_k127_10241339_3	1210884.HG799466_gene12557	8.291e-59	219.0	COG1520@1|root,COG1520@2|Bacteria,2IYNF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YHH2_k127_10241339_6	1173028.ANKO01000130_gene1836	3.72e-07	60.0	COG0642@1|root,COG2205@2|Bacteria,1G06C@1117|Cyanobacteria,1H8Z5@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_10241339_2	1288494.EBAPG3_27310	7.708e-65	241.0	COG5002@1|root,COG5002@2|Bacteria,1PUWJ@1224|Proteobacteria,2WAYZ@28216|Betaproteobacteria,371RM@32003|Nitrosomonadales	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YHH2_k127_10241339_1	748247.AZKH_p0583	1.469e-123	405.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2W1Q4@28216|Betaproteobacteria,2KXXH@206389|Rhodocyclales	206389|Rhodocyclales	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
YHH2_k127_10241339_0	1191523.MROS_1977	8.897e-224	711.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
YHH2_k127_10241339_5	1449346.JQMO01000003_gene3270	9.792e-21	106.0	COG3525@1|root,COG3525@2|Bacteria,2GK90@201174|Actinobacteria,2M4SX@2063|Kitasatospora	201174|Actinobacteria	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,RicinB_lectin_2,Ricin_B_lectin
YHH2_k127_10241339_4	880526.KE386488_gene1576	2.056e-47	188.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10251745_2	309799.DICTH_0179	4.156e-112	375.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
YHH2_k127_10251745_3	886293.Sinac_3485	6.812e-106	352.0	COG1721@1|root,COG1721@2|Bacteria,2IYDF@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YHH2_k127_10251745_0	497964.CfE428DRAFT_2755	7.873e-143	462.0	COG0714@1|root,COG0714@2|Bacteria,46U40@74201|Verrucomicrobia	2|Bacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924,ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_3,AAA_5
YHH2_k127_10251745_1	452637.Oter_2229	1.445e-134	445.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
YHH2_k127_10256742_9	1122599.AUGR01000011_gene4064	3.197e-48	179.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,1XJ8V@135619|Oceanospirillales	135619|Oceanospirillales	K	response regulator	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
YHH2_k127_10256742_7	1144319.PMI16_00016	1.137e-51	204.0	COG2202@1|root,COG2204@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VJV5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YHH2_k127_10256742_4	404589.Anae109_0139	3.629e-125	417.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
YHH2_k127_10256742_3	349741.Amuc_2115	4.463e-130	445.0	COG0172@1|root,COG0172@2|Bacteria,46S70@74201|Verrucomicrobia,2ITV1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Seryl-tRNA synthetase N-terminal domain	-	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YHH2_k127_10256742_13	1123242.JH636435_gene1741	1.278e-06	59.0	COG2165@1|root,COG2165@2|Bacteria,2IYZV@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
YHH2_k127_10256742_2	1210884.HG799463_gene10258	6.383e-147	478.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,2J25N@203682|Planctomycetes	203682|Planctomycetes	E	Amino acid kinase family	-	-	-	-	-	-	-	-	-	-	-	-	AA_kinase,Acetyltransf_1
YHH2_k127_10256742_8	452637.Oter_4232	1.023e-49	183.0	2F7MR@1|root,34028@2|Bacteria,46VN7@74201|Verrucomicrobia,3K85B@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10256742_1	1254432.SCE1572_47340	2.605e-152	500.0	COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,43203@68525|delta/epsilon subdivisions,2WWMI@28221|Deltaproteobacteria,2YTY1@29|Myxococcales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	cefD	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
YHH2_k127_10256742_5	497964.CfE428DRAFT_3399	3.192e-76	275.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YHH2_k127_10256742_10	497964.CfE428DRAFT_3472	1.148e-39	157.0	COG1579@1|root,COG1579@2|Bacteria,46T10@74201|Verrucomicrobia	74201|Verrucomicrobia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
YHH2_k127_10256742_0	1232410.KI421412_gene312	1.793e-168	552.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,43RY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	rep	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YHH2_k127_10256742_6	452637.Oter_0714	1.956e-52	194.0	COG1595@1|root,COG1639@1|root,COG1595@2|Bacteria,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	HDOD,Sigma70_r2,Sigma70_r4_2
YHH2_k127_10256742_11	452637.Oter_0712	3.002e-39	161.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
YHH2_k127_10259046_0	240016.ABIZ01000001_gene54	1.866e-131	434.0	COG3356@1|root,COG3356@2|Bacteria,46XH2@74201|Verrucomicrobia,2IVWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
YHH2_k127_10259046_2	344747.PM8797T_04035	2.834e-15	88.0	COG3250@1|root,COG3250@2|Bacteria,2J3T5@203682|Planctomycetes	203682|Planctomycetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10259046_1	765913.ThidrDRAFT_4513	4.529e-115	411.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1R3SH@1224|Proteobacteria,1S6CN@1236|Gammaproteobacteria,1WZCC@135613|Chromatiales	135613|Chromatiales	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10277003_0	452637.Oter_0312	1.279e-131	473.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
YHH2_k127_10277003_1	1192034.CAP_0893	5.167e-76	271.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
YHH2_k127_10277003_2	498761.HM1_0145	8.376e-09	68.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UHXK@1239|Firmicutes,25E6U@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,Flg_new,I-set,Laminin_G_3,SLH
YHH2_k127_10282256_1	251221.35213566	7.866e-126	426.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10282256_0	1283300.ATXB01000002_gene2987	1.636e-193	616.0	COG3391@1|root,COG3391@2|Bacteria,1QUVX@1224|Proteobacteria,1RXP0@1236|Gammaproteobacteria,1XG40@135618|Methylococcales	135618|Methylococcales	S	alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10306077_0	344747.PM8797T_29842	2.82e-39	153.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
YHH2_k127_10306077_2	1088721.NSU_2939	1.914e-14	85.0	2BZB1@1|root,32R4P@2|Bacteria,1RH72@1224|Proteobacteria,2UB2J@28211|Alphaproteobacteria,2KA29@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10306077_3	1209072.ALBT01000031_gene1886	0.0001281	50.0	COG2372@1|root,COG3209@1|root,COG2372@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	ko:K07156	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	Big_5,DUF4082,SLH
YHH2_k127_10306077_1	697281.Mahau_1354	6.905e-17	89.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YHH2_k127_10317586_1	452637.Oter_0906	2.673e-79	271.0	COG0664@1|root,COG0664@2|Bacteria,46VK1@74201|Verrucomicrobia,3K7W4@414999|Opitutae	74201|Verrucomicrobia	K	Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YHH2_k127_10317586_2	452637.Oter_0905	1.078e-19	91.0	COG4309@1|root,COG4309@2|Bacteria,46YQI@74201|Verrucomicrobia,3KA04@414999|Opitutae	414999|Opitutae	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
YHH2_k127_10317586_0	497964.CfE428DRAFT_5291	5.67e-111	369.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,46UWB@74201|Verrucomicrobia	74201|Verrucomicrobia	T	HAMP domain	-	-	2.7.13.3	ko:K07640	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
YHH2_k127_10343981_2	1123070.KB899254_gene1274	8.341e-35	136.0	COG1974@1|root,COG1974@2|Bacteria,46SU8@74201|Verrucomicrobia,2IU8D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	LexA DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LexA_DNA_bind,Peptidase_S24
YHH2_k127_10343981_0	880072.Desac_1280	1.553e-53	201.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MQGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YHH2_k127_10343981_3	497964.CfE428DRAFT_6482	3.488e-05	53.0	2FCQS@1|root,344TZ@2|Bacteria,46W38@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10343981_1	497964.CfE428DRAFT_3441	2.034e-53	192.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM UvrB UvrC protein	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
YHH2_k127_10384029_0	761193.Runsl_2879	4.025e-189	600.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,47NPG@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_10384029_3	1120973.AQXL01000134_gene1549	2.635e-70	254.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,2789J@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
YHH2_k127_10384029_1	452637.Oter_4239	1.779e-125	412.0	COG1186@1|root,COG1186@2|Bacteria,46SAW@74201|Verrucomicrobia,3K7HV@414999|Opitutae	414999|Opitutae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH2_k127_10384029_2	497964.CfE428DRAFT_4750	4.778e-110	385.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
YHH2_k127_10384029_4	497964.CfE428DRAFT_2383	7.541e-23	105.0	2F78F@1|root,33ZPQ@2|Bacteria,46VT2@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10388293_7	335541.Swol_0126	1.685e-11	72.0	COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,42K1M@68298|Syntrophomonadaceae	186801|Clostridia	M	Ami_3	lytC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1
YHH2_k127_10388293_3	1410634.JHVD01000001_gene1536	2.177e-62	223.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4DNT7@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH2_k127_10388293_6	382464.ABSI01000005_gene1327	4.77e-17	81.0	2DSQH@1|root,33H1Z@2|Bacteria,46TBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10388293_0	944479.JQLX01000010_gene642	1.089e-162	530.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
YHH2_k127_10388293_1	1499967.BAYZ01000105_gene3533	9.902e-82	287.0	COG0303@1|root,COG0303@2|Bacteria,2NP4N@2323|unclassified Bacteria	2|Bacteria	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
YHH2_k127_10388293_8	1123401.JHYQ01000009_gene2295	1.598e-10	64.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATPase, AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH2_k127_10388293_4	1123508.JH636441_gene3386	5.19e-38	165.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4347,MAM,Trypsin_2
YHH2_k127_10388293_2	926569.ANT_00890	7.507e-64	221.0	28I0T@1|root,2Z85H@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4914
YHH2_k127_10418557_2	443143.GM18_4127	1.458e-32	141.0	COG3659@1|root,COG3659@2|Bacteria,1Q0I4@1224|Proteobacteria,42WBJ@68525|delta/epsilon subdivisions,2WS5J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	-	-	-	-	-	-	-	-	-	OprB
YHH2_k127_10418557_0	497964.CfE428DRAFT_3481	2.347e-205	667.0	COG0443@1|root,COG0443@2|Bacteria,46TYN@74201|Verrucomicrobia	74201|Verrucomicrobia	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
YHH2_k127_10418557_1	497964.CfE428DRAFT_3408	2.525e-116	400.0	28M0D@1|root,2ZAFE@2|Bacteria,46TXJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative ATP-binding cassette	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran_2
YHH2_k127_10429033_5	1396141.BATP01000057_gene3053	1.924e-17	99.0	COG2312@1|root,COG3209@1|root,COG2312@2|Bacteria,COG3209@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
YHH2_k127_10429033_1	1396141.BATP01000043_gene1929	1.833e-81	311.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_10429033_4	583355.Caka_1736	3.478e-20	108.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_10429033_0	497964.CfE428DRAFT_2138	8.516e-88	302.0	COG1989@1|root,COG1989@2|Bacteria,46TWT@74201|Verrucomicrobia	74201|Verrucomicrobia	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
YHH2_k127_10429033_2	1121430.JMLG01000021_gene1382	5.981e-56	207.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2619R@186807|Peptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
YHH2_k127_10429033_3	497964.CfE428DRAFT_0033	2.768e-53	190.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
YHH2_k127_10448688_6	1526927.Plano_1573	7.458e-23	113.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HA2U@91061|Bacilli,26ED7@186818|Planococcaceae	91061|Bacilli	P	transport system permease	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
YHH2_k127_10448688_4	1121403.AUCV01000002_gene446	4.39e-58	221.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,42P50@68525|delta/epsilon subdivisions,2WKU5@28221|Deltaproteobacteria,2MMX2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
YHH2_k127_10448688_2	765420.OSCT_1968	1.274e-75	280.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
YHH2_k127_10448688_3	1303518.CCALI_00370	7.711e-65	233.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YHH2_k127_10448688_5	1125863.JAFN01000001_gene246	6.685e-28	119.0	COG5319@1|root,COG5319@2|Bacteria,1RKDX@1224|Proteobacteria,42SDV@68525|delta/epsilon subdivisions,2WPXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH2_k127_10448688_1	933262.AXAM01000047_gene2343	3.316e-106	360.0	COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,42MAE@68525|delta/epsilon subdivisions,2WKFF@28221|Deltaproteobacteria,2MKCJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Permease family	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
YHH2_k127_10448688_0	497964.CfE428DRAFT_4764	1.893e-292	924.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH2_k127_10451067_2	1403819.BATR01000178_gene5964	1.435e-136	451.0	COG1520@1|root,COG1520@2|Bacteria,46TV4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_10451067_1	123214.PERMA_0403	1.587e-150	484.0	COG0451@1|root,COG0451@2|Bacteria,2G3NS@200783|Aquificae	200783|Aquificae	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
YHH2_k127_10451067_0	118168.MC7420_6077	6.561e-189	606.0	COG5421@1|root,COG5421@2|Bacteria,1G3YW@1117|Cyanobacteria,1HHRP@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH2_k127_10453950_2	1341181.FLJC2902T_15110	1.757e-63	241.0	COG3386@1|root,COG3386@2|Bacteria,4PKPT@976|Bacteroidetes,1IKDI@117743|Flavobacteriia,2P0DY@237|Flavobacterium	976|Bacteroidetes	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
YHH2_k127_10453950_0	344747.PM8797T_13253	5.801e-164	530.0	COG2755@1|root,COG2755@2|Bacteria,2IWTR@203682|Planctomycetes	203682|Planctomycetes	E	sialic acid-specific 9-O-acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
YHH2_k127_10453950_1	530564.Psta_4044	3.961e-79	291.0	COG0515@1|root,COG0515@2|Bacteria,2IWY8@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YHH2_k127_10453950_4	195250.CM001776_gene3452	9.681e-13	80.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	ko:K18491	ko04550,map04550	-	-	-	ko00000,ko00001,ko03000	-	-	-	Collagen,DUF4132,Gln_amidase
YHH2_k127_10453950_3	926554.KI912680_gene831	1.518e-42	159.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
YHH2_k127_10466740_2	398525.KB900701_gene2983	1.368e-65	246.0	COG2159@1|root,COG2159@2|Bacteria,1ND2I@1224|Proteobacteria,2UIP1@28211|Alphaproteobacteria,3K498@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
YHH2_k127_10466740_1	1142394.PSMK_13110	1.179e-73	258.0	COG1082@1|root,COG1082@2|Bacteria,2IXZ6@203682|Planctomycetes	203682|Planctomycetes	G	isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_10466740_0	1142394.PSMK_12790	1.061e-84	293.0	COG0673@1|root,COG0673@2|Bacteria,2IY6G@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_10478493_0	1382359.JIAL01000001_gene1019	1.669e-72	250.0	COG0008@1|root,COG0008@2|Bacteria,3Y4TS@57723|Acidobacteria,2JKAU@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH2_k127_10478493_1	690850.Desaf_0923	1.316e-06	61.0	COG4733@1|root,COG4733@2|Bacteria,1NPTD@1224|Proteobacteria,42Y31@68525|delta/epsilon subdivisions,2WSU6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10521287_4	177437.HRM2_19220	1.137e-11	65.0	COG4584@1|root,COG4584@2|Bacteria	2|Bacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,HTH_7,rve
YHH2_k127_10521287_0	522306.CAP2UW1_4281	2.072e-215	692.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2VK01@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH2_k127_10521287_2	94624.Bpet1408	3.544e-41	158.0	COG3415@1|root,COG3415@2|Bacteria,1RKUV@1224|Proteobacteria,2WFVI@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29
YHH2_k127_10521287_3	394.NGR_c15980	3.115e-14	76.0	2EHAG@1|root,3394C@2|Bacteria,1NK4E@1224|Proteobacteria,2UJZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
YHH2_k127_10521287_1	177437.HRM2_19220	4.634e-74	256.0	COG4584@1|root,COG4584@2|Bacteria	2|Bacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,HTH_7,rve
YHH2_k127_10529719_2	478741.JAFS01000001_gene2129	2.188e-61	218.0	COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,37FUI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Heavy-metal-associated domain	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
YHH2_k127_10529719_1	1210884.HG799465_gene11836	3.074e-120	392.0	COG3828@1|root,COG3828@2|Bacteria,2IYPM@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
YHH2_k127_10529719_0	344747.PM8797T_07452	2.314e-175	566.0	COG2133@1|root,COG2133@2|Bacteria,2J537@203682|Planctomycetes	203682|Planctomycetes	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,ThuA
YHH2_k127_10529719_3	1396418.BATQ01000110_gene4800	6.43e-21	99.0	2E4YE@1|root,32ZSA@2|Bacteria,46WYD@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10529719_4	411902.CLOBOL_06559	2.349e-08	64.0	COG1082@1|root,COG1082@2|Bacteria,1UEHW@1239|Firmicutes,25JF3@186801|Clostridia,222DX@1506553|Lachnoclostridium	186801|Clostridia	G	AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
YHH2_k127_10540314_0	497964.CfE428DRAFT_0348	2.481e-212	685.0	COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH2_k127_10540314_1	497964.CfE428DRAFT_6231	3.202e-130	443.0	COG0745@1|root,COG5000@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,46S9G@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
YHH2_k127_10540314_3	398767.Glov_2434	4.424e-30	123.0	COG0745@1|root,COG0745@2|Bacteria	398767.Glov_2434|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10540314_2	869210.Marky_1856	3.337e-37	144.0	COG0508@1|root,COG0508@2|Bacteria,1WIIU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_10543547_1	1356854.N007_10430	4.383e-94	312.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
YHH2_k127_10543547_3	867903.ThesuDRAFT_02355	2.549e-50	193.0	COG0421@1|root,COG0421@2|Bacteria,1UI4A@1239|Firmicutes,25GIE@186801|Clostridia	186801|Clostridia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YHH2_k127_10543547_4	644966.Tmar_0214	3.872e-26	118.0	COG0421@1|root,COG0421@2|Bacteria,1UI4A@1239|Firmicutes,25GIE@186801|Clostridia	186801|Clostridia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YHH2_k127_10543547_2	118168.MC7420_8129	2.813e-56	205.0	arCOG12117@1|root,2Z9N1@2|Bacteria,1G2YP@1117|Cyanobacteria,1HE2N@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF3891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3891
YHH2_k127_10543547_0	1131269.AQVV01000050_gene421	8.92e-177	566.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
YHH2_k127_10567401_0	497964.CfE428DRAFT_1568	1.065e-39	152.0	COG0358@1|root,COG0358@2|Bacteria,46S6C@74201|Verrucomicrobia	74201|Verrucomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
YHH2_k127_10567401_3	765911.Thivi_0655	0.0009976	49.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1WY7W@135613|Chromatiales	135613|Chromatiales	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
YHH2_k127_10567401_2	889378.Spiaf_2660	1.243e-08	68.0	COG0457@1|root,COG0457@2|Bacteria,2J58Z@203691|Spirochaetes	203691|Spirochaetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
YHH2_k127_10567401_1	1122931.AUAE01000012_gene2346	5.556e-18	96.0	COG2006@1|root,COG2006@2|Bacteria,4NM3M@976|Bacteroidetes,2FQJA@200643|Bacteroidia,22ZP1@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YHH2_k127_10611216_3	251221.35210617	3.531e-36	141.0	28MI1@1|root,2ZAUV@2|Bacteria	2|Bacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH2_k127_10611216_4	448385.sce5020	1.83e-21	97.0	2CJBP@1|root,32XA7@2|Bacteria,1N4A3@1224|Proteobacteria,42X43@68525|delta/epsilon subdivisions,2WT1E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10611216_0	497964.CfE428DRAFT_3487	3.912e-120	419.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
YHH2_k127_10611216_2	102129.Lepto7375DRAFT_1999	1.125e-47	177.0	COG0784@1|root,COG0784@2|Bacteria,1G548@1117|Cyanobacteria,1HBA2@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH2_k127_10611216_1	1124780.ANNU01000013_gene3815	3.895e-91	321.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,4NGXA@976|Bacteroidetes,47NUK@768503|Cytophagia	976|Bacteroidetes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
YHH2_k127_10632201_2	485917.Phep_0353	3.068e-55	198.0	COG1073@1|root,COG1073@2|Bacteria,4P1Y4@976|Bacteroidetes	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10632201_1	1303518.CCALI_02661	3.664e-56	209.0	COG4813@1|root,COG4813@2|Bacteria	2|Bacteria	G	Trehalose utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
YHH2_k127_10632201_3	378806.STAUR_7465	9.014e-16	84.0	2BTUZ@1|root,32P2P@2|Bacteria,1Q41W@1224|Proteobacteria,439VF@68525|delta/epsilon subdivisions,2X59D@28221|Deltaproteobacteria,2Z0AG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10632201_0	761193.Runsl_2127	2.665e-157	506.0	COG4299@1|root,COG4299@2|Bacteria,4NH8T@976|Bacteroidetes,47KYS@768503|Cytophagia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
YHH2_k127_10647666_4	497964.CfE428DRAFT_1451	3.727e-139	454.0	COG1459@1|root,COG1459@2|Bacteria,46S8P@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH2_k127_10647666_0	497964.CfE428DRAFT_1455	1.361e-221	700.0	COG2804@1|root,COG2804@2|Bacteria,46UFR@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
YHH2_k127_10647666_3	452637.Oter_3084	3.373e-140	454.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH2_k127_10647666_1	497964.CfE428DRAFT_1457	1.062e-205	654.0	COG2804@1|root,COG2804@2|Bacteria,46SDR@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	General secretory system II protein E domain protein	pulE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH2_k127_10647666_6	497964.CfE428DRAFT_2346	1.194e-51	193.0	COG3694@1|root,COG3694@2|Bacteria,46VPX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
YHH2_k127_10647666_5	497964.CfE428DRAFT_2347	6.778e-70	247.0	COG4587@1|root,COG4587@2|Bacteria,46VAG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
YHH2_k127_10647666_2	794903.OPIT5_07675	4.461e-148	484.0	COG0421@1|root,COG0421@2|Bacteria,46Z5G@74201|Verrucomicrobia,3K91M@414999|Opitutae	414999|Opitutae	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10647666_7	1121468.AUBR01000015_gene2251	4.615e-49	180.0	COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,24FRV@186801|Clostridia,42I9V@68295|Thermoanaerobacterales	186801|Clostridia	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
YHH2_k127_10649616_7	1304275.C41B8_14425	2.18e-06	58.0	2E7KC@1|root,3322E@2|Bacteria,1NBFM@1224|Proteobacteria,1SDU2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Multidrug transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10649616_5	497964.CfE428DRAFT_3396	1.164e-37	147.0	2DSGX@1|root,33G2Z@2|Bacteria,46W42@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10649616_2	497964.CfE428DRAFT_4923	7.029e-115	379.0	COG0583@1|root,COG0583@2|Bacteria,46SDJ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
YHH2_k127_10649616_4	2325.TKV_c07340	2.698e-46	181.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,2491D@186801|Clostridia,42FUG@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Aminotransferase class I and II	bioF	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47,6.2.1.14	ko:K00639,ko:K00652,ko:K01906	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03209,R03210,R10124	RC00004,RC00014,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,BioW
YHH2_k127_10649616_1	1123392.AQWL01000002_gene1837	1.195e-127	416.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2VI0M@28216|Betaproteobacteria,1KSUF@119069|Hydrogenophilales	119069|Hydrogenophilales	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YHH2_k127_10649616_0	794903.OPIT5_28445	5.814e-175	566.0	COG0677@1|root,COG0677@2|Bacteria	2|Bacteria	M	UDP-N-acetyl-D-mannosamine dehydrogenase activity	wbpA	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH2_k127_10649616_3	1123242.JH636434_gene3666	1.514e-51	194.0	COG0705@1|root,COG0705@2|Bacteria,2IZJ7@203682|Planctomycetes	203682|Planctomycetes	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid,Rhomboid_N
YHH2_k127_10649616_6	1121403.AUCV01000012_gene4109	8.225e-20	102.0	COG1075@1|root,COG1075@2|Bacteria,1QD4I@1224|Proteobacteria,435MR@68525|delta/epsilon subdivisions,2X9BC@28221|Deltaproteobacteria,2MNSY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10665557_1	768671.ThimaDRAFT_0524	2.803e-107	361.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X0EW@135613|Chromatiales	135613|Chromatiales	O	Trypsin	-	-	-	ko:K04691	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
YHH2_k127_10665557_5	1122239.AULS01000005_gene1191	3.025e-16	90.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4FMI9@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YHH2_k127_10665557_3	1403819.BATR01000107_gene3658	2.396e-26	112.0	COG0799@1|root,COG0799@2|Bacteria,46T8H@74201|Verrucomicrobia,2IUTW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
YHH2_k127_10665557_4	1156937.MFUM_200030	2.293e-19	91.0	2DFNJ@1|root,2ZSFW@2|Bacteria,46WS2@74201|Verrucomicrobia,37HAT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	PurA ssDNA and RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PurA
YHH2_k127_10665557_0	338966.Ppro_2494	2.11e-147	479.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,43UHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
YHH2_k127_10665557_2	1403819.BATR01000061_gene1887	3.184e-44	169.0	COG0625@1|root,COG0625@2|Bacteria,46SQB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
YHH2_k127_10689307_2	1340493.JNIF01000003_gene2039	3.234e-75	266.0	2E9F7@1|root,333NI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10689307_1	1121017.AUFG01000010_gene1661	1.996e-174	558.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4FEQ1@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
YHH2_k127_10689307_0	1123508.JH636442_gene4219	7.227e-253	801.0	COG2373@1|root,COG2373@2|Bacteria,2IWRT@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
YHH2_k127_10701036_1	756883.Halar_1489	0.000154	54.0	COG1520@1|root,arCOG02556@2157|Archaea	2157|Archaea	O	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PQQ_2,PQQ_3
YHH2_k127_10701036_0	616991.JPOO01000003_gene1752	3.063e-29	136.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,1HZYU@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
YHH2_k127_10713338_3	543632.JOJL01000005_gene4835	2.975e-09	66.0	COG3979@1|root,COG3979@2|Bacteria,2H72H@201174|Actinobacteria,4DJJD@85008|Micromonosporales	201174|Actinobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10713338_2	1396141.BATP01000034_gene4202	1.601e-17	97.0	COG1409@1|root,COG2931@1|root,COG3210@1|root,COG3979@1|root,COG1409@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3979@2|Bacteria,46XF9@74201|Verrucomicrobia,2IVRE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	QU	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10713338_1	219305.MCAG_04073	3.981e-18	99.0	COG3979@1|root,COG3979@2|Bacteria,2H72H@201174|Actinobacteria,4DJJD@85008|Micromonosporales	201174|Actinobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10713338_0	489825.LYNGBM3L_21210	1.711e-63	231.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH2_k127_1072770_2	452637.Oter_2116	1.461e-73	260.0	COG4956@1|root,COG4956@2|Bacteria,46TFJ@74201|Verrucomicrobia,3K8ZF@414999|Opitutae	414999|Opitutae	S	SMART Nucleotide binding protein PINc	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1072770_4	1217713.F993_00565	8.93e-05	47.0	2APBA@1|root,31EDH@2|Bacteria,1RIDJ@1224|Proteobacteria,1S6VZ@1236|Gammaproteobacteria,3NN8I@468|Moraxellaceae	1236|Gammaproteobacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
YHH2_k127_1072770_0	478741.JAFS01000001_gene1692	4.099e-165	533.0	COG0277@1|root,COG0277@2|Bacteria,46SFA@74201|Verrucomicrobia,37GA5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YHH2_k127_1072770_1	1403819.BATR01000093_gene2873	1.151e-111	374.0	COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia,2ITZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_1072770_3	1123371.ATXH01000002_gene303	4.443e-25	120.0	COG1506@1|root,COG4625@1|root,COG1506@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	pip	-	4.2.2.23	ko:K06972,ko:K18195	-	-	-	-	ko00000,ko01000,ko01002	-	PL4	-	Abhydrolase_1,Autotransporter,DUF285,Peptidase_S9
YHH2_k127_10761592_11	114615.BRADO5456	6.938e-07	56.0	2DI5D@1|root,30234@2|Bacteria,1NMKN@1224|Proteobacteria,2UKB9@28211|Alphaproteobacteria,3K1Q4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
YHH2_k127_10761592_9	382464.ABSI01000005_gene1100	1.051e-33	134.0	COG0735@1|root,COG0735@2|Bacteria,46W8N@74201|Verrucomicrobia,2IUJS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH2_k127_10761592_0	234267.Acid_7699	1.077e-265	823.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
YHH2_k127_10761592_2	1121904.ARBP01000016_gene5254	5.392e-116	378.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,47N88@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
YHH2_k127_10761592_3	1382359.JIAL01000001_gene680	1.907e-107	365.0	COG0719@1|root,COG0719@2|Bacteria,3Y4EK@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
YHH2_k127_10761592_7	246197.MXAN_1157	2.443e-53	192.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,4331F@68525|delta/epsilon subdivisions,2WXKR@28221|Deltaproteobacteria,2YY54@29|Myxococcales	28221|Deltaproteobacteria	C	SUF system FeS assembly protein	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YHH2_k127_10761592_6	935863.AWZR01000013_gene1523	2.767e-59	216.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1X3XG@135614|Xanthomonadales	135614|Xanthomonadales	S	FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
YHH2_k127_10761592_1	478741.JAFS01000002_gene778	4.219e-150	486.0	COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia,37FW0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YHH2_k127_10761592_5	497964.CfE428DRAFT_0261	1.226e-61	217.0	COG0607@1|root,COG0607@2|Bacteria,46VE6@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH2_k127_10761592_8	497964.CfE428DRAFT_0260	2.933e-53	192.0	COG0822@1|root,COG0822@2|Bacteria,46VAC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NifU-like N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
YHH2_k127_10761592_4	880073.Calab_1812	7.389e-72	259.0	COG4948@1|root,COG4948@2|Bacteria,2NP34@2323|unclassified Bacteria	2|Bacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	4.2.1.113,5.1.1.20	ko:K02549,ko:K19802	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031,R10938	RC01053,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YHH2_k127_1077856_0	63737.Npun_R3025	8.395e-235	759.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
YHH2_k127_10813097_5	1123073.KB899241_gene2695	1.132e-08	58.0	COG0454@1|root,COG0456@2|Bacteria,1QB34@1224|Proteobacteria,1T6KQ@1236|Gammaproteobacteria,1X7QI@135614|Xanthomonadales	135614|Xanthomonadales	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH2_k127_10813097_4	398767.Glov_2353	5.8e-27	123.0	COG0705@1|root,COG0705@2|Bacteria,1N258@1224|Proteobacteria,42UB4@68525|delta/epsilon subdivisions,2WQJ3@28221|Deltaproteobacteria,43W1K@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH2_k127_10813097_0	1396418.BATQ01000046_gene6169	2.24e-143	469.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,46SG1@74201|Verrucomicrobia,2ITYH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
YHH2_k127_10813097_2	1121897.AUGO01000002_gene2177	1.159e-75	291.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia,2NYF6@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
YHH2_k127_10813097_6	1122176.KB903531_gene3034	1.077e-07	67.0	COG2931@1|root,COG3250@1|root,COG3291@1|root,COG5492@1|root,COG2931@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NJKV@976|Bacteroidetes,1J19W@117747|Sphingobacteriia	976|Bacteroidetes	GNQ	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase2,BACON,Big_2,F5_F8_type_C
YHH2_k127_10813097_3	1392490.JHZX01000001_gene201	1.531e-50	209.0	COG1572@1|root,COG2931@1|root,COG3211@1|root,COG3540@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3211@2|Bacteria,COG3540@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia	976|Bacteroidetes	Q	twin-arginine translocation pathway signal protein	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
YHH2_k127_10813097_1	1403819.BATR01000185_gene6430	1.418e-83	317.0	COG3121@1|root,COG3204@1|root,COG3291@1|root,COG3506@1|root,COG5184@1|root,COG3121@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
YHH2_k127_10820527_3	398767.Glov_1097	6.31e-32	142.0	COG0204@1|root,COG0204@2|Bacteria,1RA8V@1224|Proteobacteria,42SIY@68525|delta/epsilon subdivisions,2WS6P@28221|Deltaproteobacteria,43UXC@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH2_k127_10820527_4	323261.Noc_1726	8.157e-28	124.0	COG4589@1|root,COG4589@2|Bacteria,1MX58@1224|Proteobacteria,1RRAG@1236|Gammaproteobacteria,1WY6I@135613|Chromatiales	135613|Chromatiales	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
YHH2_k127_10820527_1	502025.Hoch_3411	3.661e-119	397.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YY2Q@29|Myxococcales	28221|Deltaproteobacteria	H	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
YHH2_k127_10820527_0	237368.SCABRO_01577	1.362e-197	626.0	COG0498@1|root,COG0498@2|Bacteria,2IXKE@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH2_k127_10820527_2	547042.BACCOPRO_00992	1.386e-99	351.0	COG1572@1|root,COG1572@2|Bacteria,4PJMZ@976|Bacteroidetes,2FZ9J@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
YHH2_k127_10821382_0	1396141.BATP01000028_gene2285	9.512e-18	97.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
YHH2_k127_10857000_3	1549858.MC45_15390	1.737e-08	55.0	COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,2TUX2@28211|Alphaproteobacteria,2K1QD@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YHH2_k127_10857000_0	583355.Caka_2972	2.009e-213	682.0	COG0488@1|root,COG0488@2|Bacteria,46UUC@74201|Verrucomicrobia,3K79Q@414999|Opitutae	414999|Opitutae	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH2_k127_10857000_2	243233.MCA1015	1.606e-18	95.0	COG0457@1|root,COG0457@2|Bacteria,1NNP4@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
YHH2_k127_10857000_1	497964.CfE428DRAFT_6681	7.466e-194	614.0	COG0535@1|root,COG0535@2|Bacteria,46V38@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
YHH2_k127_10876971_2	926550.CLDAP_15490	2.941e-137	445.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YHH2_k127_10876971_3	497964.CfE428DRAFT_4614	2.865e-126	418.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
YHH2_k127_10876971_5	452637.Oter_0284	5.654e-13	78.0	2DT8D@1|root,33J57@2|Bacteria,46WBF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
YHH2_k127_10876971_4	452637.Oter_0284	7.22e-40	160.0	2DT8D@1|root,33J57@2|Bacteria,46WBF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
YHH2_k127_10876971_0	1403819.BATR01000052_gene1573	3.801e-169	550.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH2_k127_10876971_1	240016.ABIZ01000001_gene508	9.354e-149	482.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,2IU1R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	UDP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH2_k127_10887216_1	935845.JADQ01000050_gene3902	5.386e-63	246.0	COG2942@1|root,COG2942@2|Bacteria,1TQMG@1239|Firmicutes,4HE7U@91061|Bacilli,26T2B@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	rnbP	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
YHH2_k127_10887216_0	485918.Cpin_5390	4.825e-87	322.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BACON,CW_binding_1,Cellulase,Collagen_bind_2,DUF4038,DUF5060
YHH2_k127_10889246_1	292459.STH1184	5.925e-09	70.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1VNAP@1239|Firmicutes,24W68@186801|Clostridia	186801|Clostridia	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
YHH2_k127_10889246_2	749414.SBI_09003	5.191e-05	57.0	COG0823@1|root,COG2304@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	HYR,PD40,REJ,VPEP,VWA
YHH2_k127_10889246_0	357808.RoseRS_0785	1.072e-219	690.0	COG0538@1|root,COG0538@2|Bacteria,2G5SM@200795|Chloroflexi,375VG@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM isocitrate dehydrogenase, NADP-dependent	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,Iso_dh
YHH2_k127_10910151_3	1396141.BATP01000060_gene4729	4.76e-64	231.0	29ZR2@1|root,30MRV@2|Bacteria,46XMI@74201|Verrucomicrobia,2IW71@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10910151_1	215803.DB30_5612	1.501e-87	297.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WMED@28221|Deltaproteobacteria,2YYEU@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
YHH2_k127_10910151_0	1713.JOFV01000023_gene1351	8.892e-102	362.0	COG4655@1|root,COG4655@2|Bacteria	2|Bacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,Tad,Tad_C
YHH2_k127_10910151_2	1121920.AUAU01000009_gene1881	8.864e-83	313.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
YHH2_k127_10910151_6	497964.CfE428DRAFT_5963	1.982e-15	88.0	2F7AY@1|root,33ZS4@2|Bacteria,46VZW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10910151_4	670487.Ocepr_0042	5.59e-50	202.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10910151_5	880073.Calab_3345	2.594e-36	146.0	COG4784@1|root,COG4784@2|Bacteria,2NS4E@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH2_k127_10934228_0	1122605.KB893626_gene2507	2.031e-124	410.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
YHH2_k127_10934228_1	1286093.C266_05424	4.605e-14	85.0	COG3210@1|root,COG4625@1|root,COG5295@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,COG5295@2|Bacteria,1MU92@1224|Proteobacteria,2VPFQ@28216|Betaproteobacteria,1K59E@119060|Burkholderiaceae	28216|Betaproteobacteria	U	outer membrane autotransporter barrel domain	-	-	-	ko:K12685	-	-	-	-	ko00000,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	-	-	Autotransporter,ESPR,PATR,Peptidase_S8
YHH2_k127_10938867_0	497964.CfE428DRAFT_6119	1.271e-186	589.0	COG0667@1|root,COG0667@2|Bacteria,46TN3@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH2_k127_10938867_4	871968.DESME_10735	2.704e-106	359.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YHH2_k127_10938867_2	1396141.BATP01000060_gene4642	2.606e-122	402.0	COG0592@1|root,COG0592@2|Bacteria,46SPK@74201|Verrucomicrobia,2ITMH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
YHH2_k127_10938867_9	673860.AciM339_1526	0.0006581	50.0	COG3815@1|root,arCOG03949@2157|Archaea,2Y6YC@28890|Euryarchaeota,3F307@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
YHH2_k127_10938867_3	344747.PM8797T_16665	4.021e-109	371.0	COG1520@1|root,COG1520@2|Bacteria,2J2HQ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_10938867_7	1184267.A11Q_150	9.157e-76	269.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,42RT7@68525|delta/epsilon subdivisions,2WVFD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
YHH2_k127_10938867_1	1122605.KB893626_gene2507	1.589e-151	496.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
YHH2_k127_10938867_8	1123487.KB892846_gene494	2.87e-10	67.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,2KX05@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
YHH2_k127_10938867_6	395493.BegalDRAFT_1263	2.593e-82	289.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
YHH2_k127_10938867_5	395493.BegalDRAFT_1262	2.38e-102	349.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
YHH2_k127_10971403_2	452637.Oter_2228	3.983e-81	277.0	COG1762@1|root,COG3311@1|root,COG1762@2|Bacteria,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	HTH_17,PTS_EIIA_2
YHH2_k127_10971403_0	595460.RRSWK_00437	4.761e-177	581.0	COG1874@1|root,COG1874@2|Bacteria,2J2PX@203682|Planctomycetes	203682|Planctomycetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10971403_1	530564.Psta_1260	6.411e-103	346.0	COG5555@1|root,COG5555@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH2_k127_10971403_4	497964.CfE428DRAFT_0021	6.838e-28	117.0	COG3668@1|root,COG3668@2|Bacteria,46WMW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_10971403_5	1158150.KB906246_gene1926	1.112e-16	85.0	COG1943@1|root,COG1943@2|Bacteria,1RBFM@1224|Proteobacteria,1SPM8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH2_k127_10971403_3	945543.VIBR0546_01991	5.274e-30	127.0	2E4R1@1|root,32ZJK@2|Bacteria,1N8FZ@1224|Proteobacteria,1SAJ2@1236|Gammaproteobacteria,1XXUY@135623|Vibrionales	135623|Vibrionales	S	Nitrous oxide-stimulated promoter	-	-	-	-	-	-	-	-	-	-	-	-	YgbA_NO
YHH2_k127_10972355_1	290397.Adeh_1677	3.007e-102	348.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,42NU5@68525|delta/epsilon subdivisions,2WJV4@28221|Deltaproteobacteria,2YX9Q@29|Myxococcales	28221|Deltaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
YHH2_k127_10972355_4	1296416.JACB01000060_gene5305	1.482e-09	66.0	COG1404@1|root,COG1404@2|Bacteria,4PPAK@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10972355_0	452637.Oter_3077	3.758e-110	400.0	COG2982@1|root,COG2982@2|Bacteria,46VEJ@74201|Verrucomicrobia,3K8PP@414999|Opitutae	414999|Opitutae	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
YHH2_k127_10972355_2	671143.DAMO_0941	3.321e-34	139.0	COG0241@1|root,COG0241@2|Bacteria,2NPK4@2323|unclassified Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K02843,ko:K03273	ko00540,ko01100,map00540,map01100	M00064,M00080	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Hydrolase_like,NTP_transferase,PRK
YHH2_k127_10972355_3	1205680.CAKO01000002_gene2136	1.365e-31	137.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10972600_1	234267.Acid_1375	9.677e-171	557.0	COG0738@1|root,COG0738@2|Bacteria,3Y324@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Major facilitator superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
YHH2_k127_10972600_2	1150600.ADIARSV_4037	5.522e-136	445.0	28HII@1|root,2Z7TZ@2|Bacteria,4NHR6@976|Bacteroidetes,1INR1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10972600_0	62928.azo0088	7.938e-196	627.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,2KVBJ@206389|Rhodocyclales	206389|Rhodocyclales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH2_k127_10980160_10	497964.CfE428DRAFT_2959	9.625e-49	183.0	2ED0A@1|root,336X9@2|Bacteria,46TCE@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10980160_12	272134.KB731324_gene5642	2.613e-38	160.0	COG4974@1|root,COG4974@2|Bacteria,1G6WZ@1117|Cyanobacteria,1HHMF@1150|Oscillatoriales	1117|Cyanobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
YHH2_k127_10980160_13	794903.OPIT5_30585	1.24e-22	113.0	COG1959@1|root,COG1959@2|Bacteria,46VNQ@74201|Verrucomicrobia,3K872@414999|Opitutae	414999|Opitutae	K	TIGRFAM transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH2_k127_10980160_4	497964.CfE428DRAFT_0621	2.893e-121	398.0	COG0150@1|root,COG0150@2|Bacteria,46SJ4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH2_k127_10980160_3	1121430.JMLG01000005_gene779	3.085e-139	458.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,2609N@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YHH2_k127_10980160_15	443143.GM18_1477	1.558e-10	72.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA-1	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
YHH2_k127_10980160_0	1123070.KB899256_gene2181	1.112e-207	668.0	COG0112@1|root,COG0112@2|Bacteria,46S5I@74201|Verrucomicrobia,2ITI6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc,LacAB_rpiB,SHMT
YHH2_k127_10980160_2	1156937.MFUM_810001	1.097e-187	599.0	COG1158@1|root,COG1158@2|Bacteria,46S5Y@74201|Verrucomicrobia,37G72@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
YHH2_k127_10980160_11	497964.CfE428DRAFT_1210	6.791e-45	177.0	2E533@1|root,32ZW9@2|Bacteria,46SZX@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_10980160_5	452637.Oter_2822	8.342e-108	366.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,3K75U@414999|Opitutae	414999|Opitutae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
YHH2_k127_10980160_1	497964.CfE428DRAFT_1208	7.968e-197	635.0	COG0755@1|root,COG0755@2|Bacteria,46SIH@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
YHH2_k127_10980160_14	857293.CAAU_1648	4.353e-11	69.0	2DBCH@1|root,2Z8DH@2|Bacteria,1UZYN@1239|Firmicutes,24B0Q@186801|Clostridia,36E61@31979|Clostridiaceae	186801|Clostridia	S	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
YHH2_k127_10980160_8	402777.KB235903_gene1978	2.138e-88	300.0	COG0363@1|root,COG0363@2|Bacteria,1G1M9@1117|Cyanobacteria,1HACM@1150|Oscillatoriales	1117|Cyanobacteria	G	6-phosphogluconolactonase glucosamine-6-phosphate isomerase deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
YHH2_k127_10980160_6	1313304.CALK_1499	8.341e-98	325.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	nagB	GO:0003674,GO:0003824,GO:0004342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006044,GO:0006046,GO:0006047,GO:0006048,GO:0006054,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016054,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0019239,GO:0019262,GO:0019438,GO:0019752,GO:0034641,GO:0034654,GO:0042737,GO:0042802,GO:0043436,GO:0043877,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046349,GO:0046395,GO:0046483,GO:0055086,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901362,GO:1901575,GO:1901576	3.1.1.31,3.5.99.6	ko:K01057,ko:K02080,ko:K02564	ko00030,ko00052,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00052,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035,R08365	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_02959,iECB_1328.ECB_03008,iECD_1391.ECD_03008,iECNA114_1301.ECNA114_3225,iECSF_1327.ECSF_2979,iYO844.BSU02360,iYO844.BSU35020,iZ_1308.Z0825	Glucosamine_iso,PIG-L
YHH2_k127_10980160_7	1313304.CALK_1498	9.833e-89	301.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_10993733_1	1200352.A606_06730	1.328e-60	216.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,22KHV@1653|Corynebacteriaceae	201174|Actinobacteria	L	Belongs to the short-chain dehydrogenases reductases (SDR) family	sdh	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
YHH2_k127_10993733_0	1268240.ATFI01000008_gene2201	4.754e-87	307.0	COG2006@1|root,COG2006@2|Bacteria,4P0ZM@976|Bacteroidetes,2FR0W@200643|Bacteroidia,4APQE@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YHH2_k127_10998081_3	1379698.RBG1_1C00001G0123	2.018e-50	183.0	COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
YHH2_k127_10998081_5	1134413.ANNK01000024_gene3516	7.676e-11	72.0	COG5036@1|root,COG5036@2|Bacteria,1TYFN@1239|Firmicutes,4HE77@91061|Bacilli,1ZDT0@1386|Bacillus	91061|Bacilli	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
YHH2_k127_10998081_4	221359.RS9916_39376	2.396e-18	96.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1G193@1117|Cyanobacteria,1H438@1129|Synechococcus	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
YHH2_k127_10998081_1	373903.Hore_12350	1.882e-74	258.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3WAD4@53433|Halanaerobiales	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
YHH2_k127_10998081_0	1131269.AQVV01000031_gene286	1.138e-133	460.0	COG4258@1|root,COG4258@2|Bacteria	2|Bacteria	I	3-demethylubiquinone-9 3-O-methyltransferase activity	hpnN	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
YHH2_k127_10998081_2	243231.GSU1901	1.398e-65	243.0	COG3170@1|root,COG3170@2|Bacteria,1MY6X@1224|Proteobacteria,42TBE@68525|delta/epsilon subdivisions,2WPBV@28221|Deltaproteobacteria,43U5N@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11006969_2	497964.CfE428DRAFT_3655	6.277e-83	281.0	COG0484@1|root,COG0484@2|Bacteria,46TKC@74201|Verrucomicrobia	74201|Verrucomicrobia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH2_k127_11006969_4	644282.Deba_2063	3.855e-33	138.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YHH2_k127_11006969_7	42256.RradSPS_0834	6.865e-12	80.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
YHH2_k127_11006969_6	1123070.KB899266_gene2494	2.143e-14	80.0	COG1595@1|root,COG1595@2|Bacteria,46WAM@74201|Verrucomicrobia,2IWJD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
YHH2_k127_11006969_0	861299.J421_2557	3.434e-195	632.0	COG0370@1|root,COG0370@2|Bacteria,1ZT1I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
YHH2_k127_11006969_5	497964.CfE428DRAFT_6371	5.387e-22	97.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015684,GO:0030001,GO:0033554,GO:0034220,GO:0034755,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070627,GO:0070838,GO:0072511,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098707,GO:0098711,GO:0098739,GO:0099587,GO:1903874	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
YHH2_k127_11006969_8	1123070.KB899250_gene635	0.0003457	48.0	COG1918@1|root,COG1918@2|Bacteria,46ZGK@74201|Verrucomicrobia,2IWG5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
YHH2_k127_11006969_1	266117.Rxyl_0146	1.218e-170	566.0	COG0243@1|root,COG0243@2|Bacteria,2GJWZ@201174|Actinobacteria,4CQ1R@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
YHH2_k127_11006969_3	1396418.BATQ01000020_gene5045	1.226e-50	184.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR
YHH2_k127_1103008_0	314230.DSM3645_10617	1.016e-96	340.0	COG3420@1|root,COG3420@2|Bacteria,2J2DV@203682|Planctomycetes	203682|Planctomycetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH2_k127_1103008_2	1089548.KI783301_gene205	1.062e-05	59.0	COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bprF	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8
YHH2_k127_1103008_1	1122176.KB903565_gene3379	3.118e-43	182.0	COG2304@1|root,COG2304@2|Bacteria,4PKD0@976|Bacteroidetes,1IXV1@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
YHH2_k127_1103008_3	1313172.YM304_35510	0.0001677	55.0	COG1520@1|root,COG3693@1|root,COG5295@1|root,COG1520@2|Bacteria,COG3693@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	3.2.1.8	ko:K01181,ko:K19233,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko02000	1.B.40,1.B.40.2	-	-	Cellulase,Collagen,YadA_anchor,YadA_head,YadA_stalk
YHH2_k127_11062094_4	330214.NIDE1868	1.462e-45	168.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,3J0UH@40117|Nitrospirae	40117|Nitrospirae	H	Pterin binding enzyme	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
YHH2_k127_11062094_2	1304880.JAGB01000001_gene819	6.464e-109	371.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
YHH2_k127_11062094_0	497964.CfE428DRAFT_2523	0.0	1374.0	COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
YHH2_k127_11062094_1	497964.CfE428DRAFT_4694	1.624e-112	376.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH2_k127_11062094_3	1123288.SOV_1c07780	4.218e-108	370.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4H6Y8@909932|Negativicutes	909932|Negativicutes	EH	Anthranilate synthase component I, N terminal region	-	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
YHH2_k127_11062094_5	1123288.SOV_1c07790	2.496e-41	164.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4H92Y@909932|Negativicutes	909932|Negativicutes	EH	Amino-transferase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
YHH2_k127_11062094_6	497964.CfE428DRAFT_2877	3.496e-21	106.0	2EU05@1|root,33MH8@2|Bacteria,46WHP@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11103929_6	937777.Deipe_0208	1.497e-36	143.0	COG0352@1|root,COG0352@2|Bacteria,1WIBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
YHH2_k127_11103929_3	497964.CfE428DRAFT_1691	2.918e-85	292.0	COG0524@1|root,COG0524@2|Bacteria,46U0Y@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH2_k127_11103929_0	1123242.JH636438_gene5875	3.866e-176	565.0	COG1520@1|root,COG1520@2|Bacteria,2IYNF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YHH2_k127_11103929_2	1210884.HG799466_gene12650	5.402e-94	331.0	28IKQ@1|root,2Z8MC@2|Bacteria,2IXYY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
YHH2_k127_11103929_1	1123508.JH636441_gene3734	1.771e-108	361.0	COG1131@1|root,COG1131@2|Bacteria,2IY1H@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_11103929_4	756272.Plabr_1385	1.04e-50	186.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,LRR_4,LRR_8
YHH2_k127_11112131_0	1223543.GP2_036_00050	7.269e-44	177.0	COG2304@1|root,COG2304@2|Bacteria,2GKDC@201174|Actinobacteria,4GBPP@85026|Gordoniaceae	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	ADP_ribosyl_GH,VWA
YHH2_k127_11112131_1	123214.PERMA_0842	7.815e-06	54.0	2C5TN@1|root,30GQP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11115219_3	1131814.JAFO01000001_gene3174	4.216e-18	87.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,3EZ7T@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
YHH2_k127_11115219_0	497964.CfE428DRAFT_2029	6.742e-101	337.0	COG0777@1|root,COG0777@2|Bacteria,46SI0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YHH2_k127_11115219_1	452637.Oter_2002	5.543e-50	183.0	COG2716@1|root,COG2716@2|Bacteria,46XGI@74201|Verrucomicrobia,3K9TK@414999|Opitutae	414999|Opitutae	E	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT_6
YHH2_k127_11115219_4	1340493.JNIF01000003_gene3006	8.293e-11	72.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Peptidase_C39,Peptidase_C39_2,Peptidase_C70
YHH2_k127_11115219_2	1089547.KB913013_gene2883	4.391e-26	111.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,47PE9@768503|Cytophagia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
YHH2_k127_11143136_3	1121403.AUCV01000018_gene3190	8.079e-89	317.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42QVZ@68525|delta/epsilon subdivisions,2WMVN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
YHH2_k127_11143136_0	335543.Sfum_2866	6.948e-177	567.0	COG2204@1|root,COG2204@2|Bacteria,1QYWF@1224|Proteobacteria,43CD6@68525|delta/epsilon subdivisions,2X7P0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
YHH2_k127_11143136_1	903818.KI912268_gene1381	9.604e-145	475.0	COG3863@1|root,COG3863@2|Bacteria	2|Bacteria	T	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
YHH2_k127_11143136_2	1340493.JNIF01000004_gene582	2.096e-90	307.0	COG3622@1|root,COG3622@2|Bacteria,3Y62G@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH2_k127_11197098_0	1121957.ATVL01000013_gene54	3.426e-110	375.0	COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,47XXW@768503|Cytophagia	976|Bacteroidetes	T	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
YHH2_k127_11197098_1	63737.Npun_F0305	1.959e-64	246.0	COG2931@1|root,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
YHH2_k127_11197098_2	1210884.HG799463_gene9785	9.751e-18	98.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Calx-beta,HemolysinCabind,Ice_nucleation
YHH2_k127_11215588_0	1410620.SHLA_36c000140	3.194e-152	485.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_11215588_4	644282.Deba_2688	7.956e-19	93.0	COG0745@1|root,COG2202@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YHH2_k127_11215588_3	518766.Rmar_2408	1.29e-21	109.0	COG0745@1|root,COG2204@1|root,COG3852@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,COG3852@2|Bacteria,4PN2Z@976|Bacteroidetes	976|Bacteroidetes	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
YHH2_k127_11215588_1	1304885.AUEY01000012_gene1786	1.758e-116	392.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIQF@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_11215588_2	1242864.D187_001666	2.214e-54	201.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
YHH2_k127_11243857_0	411490.ANACAC_03351	2.352e-46	180.0	COG0371@1|root,COG0371@2|Bacteria,1V994@1239|Firmicutes	1239|Firmicutes	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH_2
YHH2_k127_11243857_1	1304874.JAFY01000002_gene85	8.382e-11	65.0	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,3TANV@508458|Synergistetes	508458|Synergistetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YHH2_k127_11263110_0	502025.Hoch_4995	7.009e-109	356.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria,2Z2W5@29|Myxococcales	28221|Deltaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_11263110_3	583355.Caka_2246	9.888e-39	152.0	COG2940@1|root,COG2940@2|Bacteria,46W0B@74201|Verrucomicrobia,3K9P3@414999|Opitutae	414999|Opitutae	S	PFAM nuclear protein SET	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
YHH2_k127_11263110_2	530564.Psta_4691	1.369e-54	206.0	COG0731@1|root,COG0731@2|Bacteria,2IXA2@203682|Planctomycetes	203682|Planctomycetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YHH2_k127_11263110_1	452637.Oter_4074	1.957e-96	323.0	COG2169@1|root,COG4936@1|root,COG2169@2|Bacteria,COG4936@2|Bacteria,46UZR@74201|Verrucomicrobia,3K795@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PocR
YHH2_k127_11271698_11	1122135.KB893145_gene1808	0.0004317	43.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
YHH2_k127_11271698_6	1403819.BATR01000191_gene6561	2.463e-40	157.0	COG0244@1|root,COG0244@2|Bacteria,46T4Q@74201|Verrucomicrobia,2IUF1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
YHH2_k127_11271698_3	697281.Mahau_2167	8.263e-76	261.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,42ETC@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
YHH2_k127_11271698_5	497964.CfE428DRAFT_5631	1.033e-61	216.0	COG0080@1|root,COG0080@2|Bacteria,46SPZ@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
YHH2_k127_11271698_4	583355.Caka_2705	3.08e-65	228.0	COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,3K7UE@414999|Opitutae	414999|Opitutae	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
YHH2_k127_11271698_9	59374.Fisuc_1277	1.513e-06	55.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
YHH2_k127_11271698_1	319225.Plut_0178	2.59e-183	582.0	COG0050@1|root,COG0050@2|Bacteria,1FDES@1090|Chlorobi	1090|Chlorobi	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH2_k127_11271698_7	1123405.AUMM01000068_gene1664	8.611e-24	105.0	2CIV9@1|root,34A52@2|Bacteria	2|Bacteria	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
YHH2_k127_11271698_8	1262449.CP6013_0770	1.926e-23	112.0	COG0457@1|root,COG3266@1|root,COG4676@1|root,COG4870@1|root,COG0457@2|Bacteria,COG3266@2|Bacteria,COG4676@2|Bacteria,COG4870@2|Bacteria,1VDA3@1239|Firmicutes	1239|Firmicutes	O	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Flg_new,TPR_19
YHH2_k127_11271698_0	589865.DaAHT2_1112	3.745e-259	812.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
YHH2_k127_11271698_2	1167006.UWK_02600	9.062e-90	301.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
YHH2_k127_11297425_10	935863.AWZR01000006_gene1394	2.588e-17	81.0	COG0129@1|root,COG0129@2|Bacteria,1R4QF@1224|Proteobacteria,1RPTZ@1236|Gammaproteobacteria,1X9Q0@135614|Xanthomonadales	135614|Xanthomonadales	EG	Dehydratase family	-	-	4.2.1.82	ko:K22396	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
YHH2_k127_11297425_5	240015.ACP_0367	8.436e-54	213.0	COG2755@1|root,COG5301@1|root,COG2755@2|Bacteria,COG5301@2|Bacteria,3Y82Q@57723|Acidobacteria,2JN5M@204432|Acidobacteriia	204432|Acidobacteriia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11297425_6	240015.ACP_0367	5.746e-51	204.0	COG2755@1|root,COG5301@1|root,COG2755@2|Bacteria,COG5301@2|Bacteria,3Y82Q@57723|Acidobacteria,2JN5M@204432|Acidobacteriia	204432|Acidobacteriia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11297425_3	1396141.BATP01000027_gene1172	8.911e-90	305.0	COG0101@1|root,COG0101@2|Bacteria,46SSV@74201|Verrucomicrobia,2IU7R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_1
YHH2_k127_11297425_8	478741.JAFS01000002_gene271	2.182e-36	142.0	COG0816@1|root,COG0816@2|Bacteria,46T51@74201|Verrucomicrobia,37GTE@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	rnhD	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
YHH2_k127_11297425_0	497964.CfE428DRAFT_1556	1.397e-180	574.0	COG0001@1|root,COG0001@2|Bacteria,46S67@74201|Verrucomicrobia	74201|Verrucomicrobia	H	intramolecular transferase activity, transferring amino groups	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH2_k127_11297425_1	1278073.MYSTI_03884	2.476e-105	357.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	nla6	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_11297425_7	1121929.KB898669_gene3196	1.273e-41	163.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,471NJ@74385|Gracilibacillus	91061|Bacilli	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
YHH2_k127_11297425_11	1210884.HG799464_gene10454	0.0009272	47.0	2DXZ8@1|root,3479Q@2|Bacteria,2J3XJ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11297425_4	497964.CfE428DRAFT_4165	4.957e-54	195.0	COG0245@1|root,COG0245@2|Bacteria,46T29@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
YHH2_k127_11297425_2	517418.Ctha_0917	4.93e-91	309.0	COG0226@1|root,COG0226@2|Bacteria,1FE4N@1090|Chlorobi	1090|Chlorobi	P	TIGRFAM phosphate binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
YHH2_k127_11297425_9	685035.ADAE01000018_gene578	1.939e-30	134.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2TQMN@28211|Alphaproteobacteria,2K0AA@204457|Sphingomonadales	204457|Sphingomonadales	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
YHH2_k127_11335523_1	1131269.AQVV01000028_gene28	4.445e-110	399.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	speE	GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
YHH2_k127_11335523_3	264732.Moth_0582	4.025e-69	250.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,42F9T@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
YHH2_k127_11335523_6	1304885.AUEY01000053_gene157	2.483e-21	94.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2MKYU@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
YHH2_k127_11335523_4	1396141.BATP01000060_gene4688	1.966e-68	243.0	COG3253@1|root,COG3253@2|Bacteria,46SQD@74201|Verrucomicrobia,2IVHP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
YHH2_k127_11335523_0	1173026.Glo7428_2698	4.543e-160	544.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YHH2_k127_11335523_2	351627.Csac_2254	1.566e-100	341.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YHH2_k127_11335523_5	65393.PCC7424_1997	3.608e-26	126.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1G4IS@1117|Cyanobacteria,3KKQ9@43988|Cyanothece	1117|Cyanobacteria	QU	PFAM Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind
YHH2_k127_11335523_7	316067.Geob_1283	2.282e-14	87.0	COG1361@1|root,COG1404@1|root,COG3210@1|root,COG4625@1|root,COG4886@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Cadherin_3,DUF11,DUF4347,He_PIG,PATR
YHH2_k127_11339054_0	240016.ABIZ01000001_gene608	4.736e-147	479.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,2IVCR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_11339054_4	439235.Dalk_3070	8.616e-96	349.0	COG4262@1|root,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,42Q43@68525|delta/epsilon subdivisions,2WKQF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
YHH2_k127_11339054_1	886379.AEWI01000018_gene1289	7.718e-129	424.0	COG1180@1|root,COG1180@2|Bacteria,4NJ18@976|Bacteroidetes,2FQZB@200643|Bacteroidia,3XM0S@558415|Marinilabiliaceae	976|Bacteroidetes	O	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
YHH2_k127_11339054_3	1499967.BAYZ01000152_gene1436	2.843e-98	340.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2NPAA@2323|unclassified Bacteria	2|Bacteria	S	AMMECR1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
YHH2_k127_11339054_2	886293.Sinac_7310	1.634e-114	375.0	COG1413@1|root,COG1413@2|Bacteria,2IYWU@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_11369794_0	226186.BT_4426	7.826e-151	492.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia,4AW28@815|Bacteroidaceae	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11369794_3	935863.AWZR01000014_gene2989	5.13e-07	59.0	2EHSB@1|root,33BI2@2|Bacteria	2|Bacteria	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
YHH2_k127_11369794_1	478741.JAFS01000002_gene501	1.516e-42	173.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	MFS_1
YHH2_k127_11369794_2	1444712.BN1013_01574	7.182e-28	114.0	COG0184@1|root,COG0184@2|Bacteria,2JG4W@204428|Chlamydiae	204428|Chlamydiae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
YHH2_k127_11434097_7	452637.Oter_1662	6.681e-61	226.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia,3K7B8@414999|Opitutae	414999|Opitutae	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
YHH2_k127_11434097_9	880070.Cycma_4845	3.523e-44	171.0	COG2133@1|root,COG2133@2|Bacteria,4PNNH@976|Bacteroidetes,47KNR@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_11434097_11	794903.OPIT5_30485	6.377e-38	154.0	COG2374@1|root,COG2374@2|Bacteria,46VEK@74201|Verrucomicrobia,3K81M@414999|Opitutae	414999|Opitutae	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH2_k127_11434097_3	497964.CfE428DRAFT_3386	2.35e-104	345.0	COG1469@1|root,COG1469@2|Bacteria,46SIB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
YHH2_k127_11434097_13	481448.Minf_1016	3.189e-30	130.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia,37GP1@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
YHH2_k127_11434097_15	1353529.M899_0700	1.635e-20	91.0	COG0267@1|root,COG0267@2|Bacteria,1Q1V0@1224|Proteobacteria,437HE@68525|delta/epsilon subdivisions,2MTDQ@213481|Bdellovibrionales,2X2QY@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
YHH2_k127_11434097_16	1156937.MFUM_180008	2.294e-12	75.0	COG0238@1|root,COG0238@2|Bacteria,46TBC@74201|Verrucomicrobia,37HB4@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein S18	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
YHH2_k127_11434097_10	555079.Toce_0911	5.539e-44	172.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,42FBX@68295|Thermoanaerobacterales	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
YHH2_k127_11434097_14	1262914.BN533_01642	1.833e-24	111.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4H4QY@909932|Negativicutes	909932|Negativicutes	G	Belongs to the phosphoglycerate mutase family	cobC	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
YHH2_k127_11434097_5	240016.ABIZ01000001_gene913	3.319e-94	314.0	COG0689@1|root,COG0689@2|Bacteria,46U55@74201|Verrucomicrobia,2ITNM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
YHH2_k127_11434097_4	1210884.HG799473_gene15022	4.748e-98	329.0	COG1028@1|root,COG1028@2|Bacteria,2IXFA@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH2_k127_11434097_1	497964.CfE428DRAFT_0790	5.062e-183	585.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
YHH2_k127_11434097_0	497964.CfE428DRAFT_2513	1.173e-197	629.0	COG1543@1|root,COG1543@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K03406,ko:K16149	ko00500,ko01100,ko01110,ko02020,ko02030,map00500,map01100,map01110,map02020,map02030	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko02035	-	GH57	-	DUF1957,Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1
YHH2_k127_11434097_8	497964.CfE428DRAFT_4931	8.166e-57	215.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912,Rho_N
YHH2_k127_11434097_17	575540.Isop_3677	8.663e-10	64.0	COG0745@1|root,COG0745@2|Bacteria,2J342@203682|Planctomycetes	203682|Planctomycetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
YHH2_k127_11434097_18	1156937.MFUM_810006	5.872e-07	55.0	2AZ1N@1|root,31R7T@2|Bacteria,46ZFC@74201|Verrucomicrobia,37GYK@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11434097_19	478741.JAFS01000002_gene903	0.0002104	48.0	2CDBP@1|root,302Y8@2|Bacteria,46ZF1@74201|Verrucomicrobia,37HD2@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11434097_2	497964.CfE428DRAFT_2456	1.294e-113	374.0	COG0685@1|root,COG0685@2|Bacteria,46U74@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
YHH2_k127_11434097_6	1120956.JHZK01000018_gene2426	4.504e-64	229.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,1JNTA@119043|Rhodobiaceae	28211|Alphaproteobacteria	K	Sir2 family	MA20_30275	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
YHH2_k127_11434097_12	1120971.AUCA01000007_gene2205	6.979e-31	124.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes	1239|Firmicutes	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
YHH2_k127_11489807_0	1267533.KB906738_gene2397	1.229e-130	432.0	COG3250@1|root,COG3250@2|Bacteria,3Y47P@57723|Acidobacteria,2JKBC@204432|Acidobacteriia	204432|Acidobacteriia	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH2_k127_11489807_1	1303518.CCALI_00143	8.4e-103	349.0	COG3664@1|root,COG3664@2|Bacteria	2|Bacteria	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_39,Glyco_hydro_42
YHH2_k127_11489807_3	1120950.KB892758_gene6363	3.692e-35	154.0	COG3664@1|root,COG3664@2|Bacteria,2IDT6@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11489807_5	278957.ABEA03000201_gene4321	8.915e-12	79.0	COG1450@1|root,COG1450@2|Bacteria,46UJF@74201|Verrucomicrobia,3K7CH@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
YHH2_k127_11489807_2	452637.Oter_2031	3.624e-74	259.0	COG0288@1|root,COG0288@2|Bacteria	2|Bacteria	P	reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
YHH2_k127_11489807_4	452637.Oter_2033	7.301e-25	104.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
YHH2_k127_1150317_1	497964.CfE428DRAFT_5311	5.28e-172	552.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH2_k127_1150317_0	344747.PM8797T_03955	2.26e-198	644.0	COG3064@1|root,COG3064@2|Bacteria,2IWVN@203682|Planctomycetes	203682|Planctomycetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PPC
YHH2_k127_11525441_1	344747.PM8797T_17187	5.684e-86	289.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11525441_0	518766.Rmar_1740	3.293e-111	376.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1FK20@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_11525441_2	314230.DSM3645_14090	2.837e-64	231.0	COG1413@1|root,COG3828@1|root,COG1413@2|Bacteria,COG3828@2|Bacteria,2IX8S@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_11525441_3	935845.JADQ01000029_gene1230	3.025e-31	129.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
YHH2_k127_11544976_0	1120950.KB892747_gene3702	2.566e-137	461.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	GxGYxYP_C,GxGYxYP_N
YHH2_k127_11544976_5	190650.CC_0572	1.619e-15	88.0	COG5434@1|root,COG5434@2|Bacteria,1QH2X@1224|Proteobacteria,2U1H2@28211|Alphaproteobacteria,2KHXQ@204458|Caulobacterales	204458|Caulobacterales	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
YHH2_k127_11544976_1	278957.ABEA03000206_gene3779	3.282e-127	414.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,3K7P4@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
YHH2_k127_11544976_3	945713.IALB_1460	1.553e-31	130.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	ko:K14061	-	-	-	-	ko00000	-	-	-	Usp
YHH2_k127_11544976_4	1499967.BAYZ01000118_gene3298	2.906e-20	93.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_25,Trm112p
YHH2_k127_11544976_2	497964.CfE428DRAFT_1480	1.2e-32	130.0	COG1641@1|root,COG1641@2|Bacteria,46THK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF111
YHH2_k127_11548930_4	497964.CfE428DRAFT_6050	6.085e-54	193.0	COG0657@1|root,COG0657@2|Bacteria,46SRP@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
YHH2_k127_11548930_3	1340493.JNIF01000003_gene2256	5.367e-66	237.0	COG3828@1|root,COG3828@2|Bacteria,3Y6YX@57723|Acidobacteria	57723|Acidobacteria	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
YHH2_k127_11548930_0	497964.CfE428DRAFT_6049	6.798e-173	556.0	COG0673@1|root,COG0673@2|Bacteria,46U0A@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_11548930_2	344747.PM8797T_20763	4.621e-98	339.0	COG1331@1|root,COG1331@2|Bacteria,2IXCB@203682|Planctomycetes	203682|Planctomycetes	O	Pectic acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
YHH2_k127_11548930_1	1122605.KB893625_gene1943	2.089e-111	376.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1IUUU@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH2_k127_1157775_0	497964.CfE428DRAFT_1301	1.212e-68	252.0	COG3598@1|root,COG3598@2|Bacteria	2|Bacteria	L	Psort location Cytoplasmic, score	-	-	-	ko:K07505	-	-	-	-	ko00000	-	-	-	AAA_25,PriCT_2
YHH2_k127_1157775_4	497964.CfE428DRAFT_1407	2.41e-17	95.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YHH2_k127_1157775_2	240016.ABIZ01000001_gene3798	5.105e-24	116.0	COG0582@1|root,COG0582@2|Bacteria,46T2Q@74201|Verrucomicrobia,2IV0J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YHH2_k127_1157775_3	370438.PTH_2877	6.694e-23	104.0	COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1UXUR@1239|Firmicutes,2594M@186801|Clostridia,262BM@186807|Peptococcaceae	186801|Clostridia	L	DNA primase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Toprim_2
YHH2_k127_1158011_7	644282.Deba_1749	2.065e-45	175.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C2A@68525|delta/epsilon subdivisions,2X7CW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
YHH2_k127_1158011_4	316067.Geob_1632	9.985e-139	465.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
YHH2_k127_1158011_6	459495.SPLC1_S040030	4.414e-83	286.0	COG0378@1|root,COG0378@2|Bacteria,1G2X6@1117|Cyanobacteria,1H8P3@1150|Oscillatoriales	1117|Cyanobacteria	KO	Ni2 binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
YHH2_k127_1158011_9	118173.KB235910_gene4735	2.04e-25	109.0	COG0375@1|root,COG0375@2|Bacteria,1G89Y@1117|Cyanobacteria,1HCJX@1150|Oscillatoriales	1117|Cyanobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
YHH2_k127_1158011_5	1403819.BATR01000178_gene5960	3.448e-101	338.0	COG1082@1|root,COG1082@2|Bacteria,46SR1@74201|Verrucomicrobia,2IW0I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_1158011_8	322710.Avin_50390	1.426e-42	167.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH2_k127_1158011_0	595460.RRSWK_04532	1.363e-194	614.0	COG0673@1|root,COG0673@2|Bacteria,2IXPT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_1158011_2	314282.PCNPT3_07895	3.072e-147	490.0	COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH2_k127_1158011_3	509191.AEDB02000072_gene2034	1.327e-146	474.0	COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,247MU@186801|Clostridia,3WHBT@541000|Ruminococcaceae	186801|Clostridia	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
YHH2_k127_1158011_1	1047013.AQSP01000120_gene936	3.702e-166	535.0	COG4354@1|root,COG4354@2|Bacteria,2NQ9B@2323|unclassified Bacteria	2|Bacteria	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,Glyco_hydr_116N
YHH2_k127_11615316_2	497964.CfE428DRAFT_2063	8.795e-27	112.0	COG0736@1|root,COG0736@2|Bacteria,46T5U@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
YHH2_k127_11615316_3	1396141.BATP01000059_gene2386	1.019e-22	100.0	COG0361@1|root,COG0361@2|Bacteria,46T5J@74201|Verrucomicrobia,2IUS9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
YHH2_k127_11615316_1	1403819.BATR01000162_gene5396	1.08e-82	280.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase,Polyketide_cyc2
YHH2_k127_11615316_0	344747.PM8797T_10414	1.574e-181	579.0	COG0673@1|root,COG0673@2|Bacteria,2J2IK@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_11623842_1	1366050.N234_34925	2.686e-114	378.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW8A@1224|Proteobacteria,2VPNY@28216|Betaproteobacteria,1K7N5@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
YHH2_k127_11623842_2	926550.CLDAP_17040	2.032e-25	124.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
YHH2_k127_11623842_3	1380355.JNIJ01000004_gene2769	2.134e-19	104.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,Laminin_G_3,PPC
YHH2_k127_11623842_0	478741.JAFS01000001_gene1901	1.965e-133	443.0	COG1249@1|root,COG1249@2|Bacteria,46S8I@74201|Verrucomicrobia,37GDC@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH2_k127_11623842_4	497964.CfE428DRAFT_0698	4.51e-19	92.0	COG3558@1|root,COG3558@2|Bacteria,46T07@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
YHH2_k127_11679599_4	497964.CfE428DRAFT_0064	1.218e-30	130.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
YHH2_k127_11679599_0	382464.ABSI01000012_gene2146	2.752e-177	576.0	COG1593@1|root,COG1593@2|Bacteria	2|Bacteria	G	mannitol 2-dehydrogenase activity	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM,DctQ
YHH2_k127_11679599_1	1100720.ALKN01000007_gene2915	1.402e-105	353.0	COG1638@1|root,COG1638@2|Bacteria,1PMWE@1224|Proteobacteria,2VNJI@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
YHH2_k127_11679599_2	335543.Sfum_2673	7.487e-90	306.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
YHH2_k127_11679599_3	497964.CfE428DRAFT_3997	1.386e-64	233.0	COG0515@1|root,COG0515@2|Bacteria,46TX9@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RicinB_lectin_2
YHH2_k127_11705906_0	497964.CfE428DRAFT_2683	4.849e-109	361.0	COG5426@1|root,COG5426@2|Bacteria,46U69@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11705906_1	497964.CfE428DRAFT_2689	3.018e-107	368.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	3.1.3.3,3.5.1.28	ko:K01448,ko:K07315,ko:K21470	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03021,ko03036	-	-	-	-
YHH2_k127_11705906_5	63737.Npun_DF046	2.456e-39	167.0	COG3039@1|root,COG3039@2|Bacteria,1G3IA@1117|Cyanobacteria,1HKMU@1161|Nostocales	1117|Cyanobacteria	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
YHH2_k127_11705906_4	449447.MAE_12430	4.574e-41	177.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04W@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Proprotein convertase P-domain	prcA	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
YHH2_k127_11705906_6	8090.ENSORLP00000013362	2.261e-18	102.0	KOG1306@1|root,KOG1306@2759|Eukaryota,38CSX@33154|Opisthokonta,3BAVY@33208|Metazoa,3CSR1@33213|Bilateria,482DN@7711|Chordata,499WN@7742|Vertebrata,49Q16@7898|Actinopterygii	33208|Metazoa	PT	sodium calcium exchanger	Calx	GO:0003008,GO:0003674,GO:0005215,GO:0005432,GO:0005488,GO:0005509,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006816,GO:0006950,GO:0007154,GO:0007165,GO:0007602,GO:0008150,GO:0008324,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009605,GO:0009628,GO:0009987,GO:0015075,GO:0015077,GO:0015081,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015318,GO:0015368,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0023052,GO:0030001,GO:0032501,GO:0033554,GO:0034220,GO:0034976,GO:0035725,GO:0043167,GO:0043169,GO:0046872,GO:0046873,GO:0050789,GO:0050794,GO:0050877,GO:0050884,GO:0050896,GO:0050905,GO:0051179,GO:0051234,GO:0051606,GO:0051716,GO:0055085,GO:0065007,GO:0070588,GO:0070838,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516	-	ko:K05849	ko04020,ko04022,ko04371,ko04740,ko04974,map04020,map04022,map04371,map04740,map04974	-	-	-	ko00000,ko00001,ko00536,ko02000	2.A.19.3	-	-	Calx-beta,Na_Ca_ex,Na_Ca_ex_C
YHH2_k127_11705906_2	1341181.FLJC2902T_15110	8.284e-93	347.0	COG3386@1|root,COG3386@2|Bacteria,4PKPT@976|Bacteroidetes,1IKDI@117743|Flavobacteriia,2P0DY@237|Flavobacterium	976|Bacteroidetes	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
YHH2_k127_11705906_3	304371.MCP_2796	5.426e-51	210.0	arCOG06738@1|root,arCOG06738@2157|Archaea	2157|Archaea	O	extracellular matrix structural constituent	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	Beta_helix,Calx-beta,CarboxypepD_reg,NosD,Peptidase_S8
YHH2_k127_11721046_3	497964.CfE428DRAFT_2202	1.922e-25	119.0	COG3307@1|root,COG3307@2|Bacteria,46TC1@74201|Verrucomicrobia	74201|Verrucomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH2_k127_11721046_0	497964.CfE428DRAFT_2506	2.44e-242	754.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
YHH2_k127_11721046_1	240016.ABIZ01000001_gene3008	9.067e-144	469.0	COG1520@1|root,COG1520@2|Bacteria,46U6I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_11721046_2	278957.ABEA03000050_gene160	7.551e-32	128.0	COG1051@1|root,COG1051@2|Bacteria,46V5B@74201|Verrucomicrobia,3K7WB@414999|Opitutae	414999|Opitutae	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YHH2_k127_11725890_3	1449126.JQKL01000009_gene363	3.912e-20	96.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,26ARS@186813|unclassified Clostridiales	186801|Clostridia	EH	chorismate binding enzyme	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
YHH2_k127_11725890_1	497964.CfE428DRAFT_4694	4.891e-116	387.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH2_k127_11725890_2	861299.J421_0058	1.583e-69	243.0	COG1611@1|root,COG1611@2|Bacteria,1ZT7E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH2_k127_11725890_0	234267.Acid_1375	1.808e-222	698.0	COG0738@1|root,COG0738@2|Bacteria,3Y324@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Major facilitator superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
YHH2_k127_11725890_4	635013.TherJR_2040	4.489e-07	52.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,261GI@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH2_k127_1173915_4	338963.Pcar_2425	2.124e-17	83.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH2_k127_1173915_0	247490.KSU1_C0286	5.028e-142	467.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	vnfA	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
YHH2_k127_1173915_3	643562.Daes_2499	2.499e-36	156.0	COG3303@1|root,COG3303@2|Bacteria,1QX6Q@1224|Proteobacteria,42MHA@68525|delta/epsilon subdivisions,2WMF3@28221|Deltaproteobacteria,2MFXQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
YHH2_k127_1173915_2	1266925.JHVX01000007_gene2261	8.943e-106	362.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,2WGGV@28216|Betaproteobacteria,373PP@32003|Nitrosomonadales	28216|Betaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	copS	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
YHH2_k127_1173915_1	1123508.JH636444_gene5245	3.554e-110	359.0	COG0745@1|root,COG0745@2|Bacteria,2IYM1@203682|Planctomycetes	203682|Planctomycetes	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_11742399_1	1122925.KB895378_gene2567	4.484e-21	100.0	COG1409@1|root,COG3250@1|root,COG3291@1|root,COG5492@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
YHH2_k127_11742399_0	1288963.ADIS_1256	1.751e-169	547.0	COG3408@1|root,COG3408@2|Bacteria,4NIK8@976|Bacteroidetes	976|Bacteroidetes	G	Trehalase	ygjK	-	-	ko:K03931	-	-	-	-	ko00000	-	GH63	-	Trehalase
YHH2_k127_11767910_5	452637.Oter_0312	1.687e-11	78.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
YHH2_k127_11767910_2	383372.Rcas_2969	3.592e-42	179.0	COG2373@1|root,COG2373@2|Bacteria,2GBMN@200795|Chloroflexi,377SP@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11767910_3	1123277.KB893203_gene6265	3.592e-42	179.0	COG2373@1|root,COG3291@1|root,COG4932@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4NJQN@976|Bacteroidetes,47QVQ@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
YHH2_k127_11767910_4	497964.CfE428DRAFT_3521	5.396e-24	106.0	COG2010@1|root,COG2010@2|Bacteria,46TD5@74201|Verrucomicrobia	2|Bacteria	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
YHH2_k127_11767910_0	886293.Sinac_5697	5.23e-193	608.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_11767910_1	344747.PM8797T_17402	4.349e-135	434.0	COG1082@1|root,COG1082@2|Bacteria,2IY10@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_11773596_1	1156937.MFUM_290037	7.042e-69	236.0	COG0440@1|root,COG0440@2|Bacteria,46SUP@74201|Verrucomicrobia,37GJ7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	ACT domain	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
YHH2_k127_11773596_4	1313421.JHBV01000020_gene5291	1.427e-15	88.0	2BFSG@1|root,329MB@2|Bacteria,4NRMX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11773596_2	1107311.Q767_12240	1.339e-59	209.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1I1XN@117743|Flavobacteriia,2NW14@237|Flavobacterium	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
YHH2_k127_11773596_0	251229.Chro_4403	1.414e-259	826.0	COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,3VI6E@52604|Pleurocapsales	1117|Cyanobacteria	O	PFAM HypF finger	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
YHH2_k127_11773596_3	272134.KB731324_gene5868	7.832e-19	91.0	COG0298@1|root,COG0298@2|Bacteria	2|Bacteria	O	carbon dioxide binding	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
YHH2_k127_11782118_0	926550.CLDAP_17510	7.375e-196	652.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_11828998_3	1123269.NX02_11330	5.19e-06	49.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2TSUA@28211|Alphaproteobacteria,2K3EB@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
YHH2_k127_11828998_2	278963.ATWD01000001_gene3285	9.054e-08	53.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YHH2_k127_11828998_4	204669.Acid345_0372	2.855e-05	51.0	COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria,2JHYU@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH2_k127_11828998_0	192952.MM_3198	4.024e-88	305.0	COG1073@1|root,arCOG01661@2157|Archaea,2XVIC@28890|Euryarchaeota,2NANZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S9
YHH2_k127_11828998_1	1089547.KB913013_gene1588	6.172e-09	61.0	COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,47YC1@768503|Cytophagia	976|Bacteroidetes	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
YHH2_k127_11841847_1	497964.CfE428DRAFT_0416	4.607e-114	381.0	COG2010@1|root,COG2010@2|Bacteria,46TRF@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_11841847_2	1195236.CTER_0563	3.659e-42	165.0	COG0145@1|root,COG0145@2|Bacteria,1V3GN@1239|Firmicutes,25DNJ@186801|Clostridia,3WPEF@541000|Ruminococcaceae	186801|Clostridia	EQ	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
YHH2_k127_11841847_0	1403819.BATR01000162_gene5320	2.764e-192	605.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_11848520_0	1123508.JH636439_gene943	3.361e-290	944.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Calx-beta,DUF1863,PQQ,PQQ_2,PQQ_3,P_proprotein,Peptidase_S8,SBBP,VCBS
YHH2_k127_11865935_1	583355.Caka_0965	5.929e-68	256.0	COG0823@1|root,COG1413@1|root,COG0823@2|Bacteria,COG1413@2|Bacteria,46XCP@74201|Verrucomicrobia,3K9X8@414999|Opitutae	414999|Opitutae	U	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11865935_0	1191523.MROS_0971	6.757e-79	275.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH2_k127_11876609_10	1121456.ATVA01000011_gene1525	1.797e-33	132.0	COG1566@1|root,COG1566@2|Bacteria,1QUDS@1224|Proteobacteria,42QZG@68525|delta/epsilon subdivisions,2WN4C@28221|Deltaproteobacteria,2M8IJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
YHH2_k127_11876609_3	1163617.SCD_n00179	5.748e-138	445.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VHRB@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_11876609_2	1121918.ARWE01000001_gene2821	1.932e-160	518.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42N83@68525|delta/epsilon subdivisions,2WJFF@28221|Deltaproteobacteria,43T0V@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH2_k127_11876609_5	1265505.ATUG01000001_gene4623	4.476e-112	376.0	COG0477@1|root,COG2814@2|Bacteria,1R518@1224|Proteobacteria,43B4F@68525|delta/epsilon subdivisions,2WIQ4@28221|Deltaproteobacteria,2MIEM@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH2_k127_11876609_1	616991.JPOO01000001_gene3033	3.048e-180	584.0	COG3119@1|root,COG3119@2|Bacteria,4NGPC@976|Bacteroidetes,1I0MV@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH2_k127_11876609_0	478741.JAFS01000002_gene868	1.089e-217	688.0	COG0119@1|root,COG0119@2|Bacteria,46TQ5@74201|Verrucomicrobia,37G4P@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
YHH2_k127_11876609_6	743719.PaelaDRAFT_2908	2.876e-99	338.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,26R0E@186822|Paenibacillaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YHH2_k127_11876609_8	1396141.BATP01000007_gene5666	2.731e-43	161.0	COG0509@1|root,COG0509@2|Bacteria,46VKU@74201|Verrucomicrobia,2IUJ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
YHH2_k127_11876609_9	635013.TherJR_0253	5.035e-43	167.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,261YY@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
YHH2_k127_11876609_4	497964.CfE428DRAFT_2715	1.922e-116	389.0	COG0793@1|root,COG0793@2|Bacteria,46SM7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
YHH2_k127_11876609_7	1396141.BATP01000022_gene409	4.758e-91	314.0	COG0533@1|root,COG0533@2|Bacteria,46SEH@74201|Verrucomicrobia,2ITUT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YHH2_k127_11885997_4	1210884.HG799463_gene9709	2.326e-63	226.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IWWQ@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
YHH2_k127_11885997_3	768671.ThimaDRAFT_3418	1.514e-76	267.0	COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,1WXRA@135613|Chromatiales	135613|Chromatiales	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH2_k127_11885997_0	1183438.GKIL_2326	6.5e-126	414.0	COG0399@1|root,COG0399@2|Bacteria,1G0IM@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH2_k127_11885997_1	404589.Anae109_3548	2.059e-98	366.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
YHH2_k127_11885997_6	935567.JAES01000033_gene858	5.504e-17	82.0	2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria,1SJFZ@1236|Gammaproteobacteria,1X82Y@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11885997_5	2045.KR76_08180	5.202e-44	179.0	COG1524@1|root,COG1524@2|Bacteria,2HY6Q@201174|Actinobacteria,4DT1Q@85009|Propionibacteriales	201174|Actinobacteria	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
YHH2_k127_11885997_2	96561.Dole_1668	1.101e-76	263.0	2CCV8@1|root,2Z7KX@2|Bacteria,1MY2J@1224|Proteobacteria,42PUV@68525|delta/epsilon subdivisions,2WKCH@28221|Deltaproteobacteria,2MJRG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
YHH2_k127_11906311_0	886293.Sinac_4679	6.519e-163	530.0	2DBKQ@1|root,2Z9U7@2|Bacteria,2IWVD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11906311_1	573061.Clocel_1966	8.956e-29	130.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH2_k127_11906383_4	497964.CfE428DRAFT_3344	1.361e-47	177.0	COG1204@1|root,COG1204@2|Bacteria,46SCW@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
YHH2_k127_11906383_2	1121104.AQXH01000001_gene1321	2.97e-88	304.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
YHH2_k127_11906383_5	1131814.JAFO01000001_gene2573	3.27e-42	158.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR
YHH2_k127_11906383_3	1117318.PRUB_22871	8.934e-61	227.0	COG2335@1|root,COG4315@1|root,COG2335@2|Bacteria,COG4315@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria,2Q18Y@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	ko:K19519	-	-	-	-	ko00000,ko04516	-	-	-	Fasciclin,Lipoprotein_15
YHH2_k127_11906383_1	497964.CfE428DRAFT_2485	6.129e-187	591.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_11906383_0	1396418.BATQ01000093_gene5884	3.253e-277	857.0	COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia,2ITWP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiC-associated domain	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
YHH2_k127_1220944_0	1244869.H261_07368	1.351e-127	424.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,2JQ6Q@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
YHH2_k127_1220944_1	886293.Sinac_2603	8.815e-99	332.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YHH2_k127_1220944_2	1396141.BATP01000039_gene1275	3.561e-86	301.0	COG2202@1|root,COG5000@1|root,COG2202@2|Bacteria,COG5000@2|Bacteria,46S9G@74201|Verrucomicrobia,2IVKV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_1220944_4	497964.CfE428DRAFT_6232	3.584e-23	104.0	COG0745@1|root,COG0745@2|Bacteria,46W19@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH2_k127_1220944_3	398767.Glov_2434	3.431e-32	133.0	COG0745@1|root,COG0745@2|Bacteria	398767.Glov_2434|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1271418_0	641524.ADICYQ_0727	1.674e-169	557.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1271418_1	583355.Caka_1736	1.35e-132	466.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_1274377_3	1206733.BAGC01000044_gene912	0.0003703	43.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4G037@85025|Nocardiaceae	201174|Actinobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH2_k127_1274377_0	497964.CfE428DRAFT_0259	3.578e-53	192.0	COG2151@1|root,COG2151@2|Bacteria,46SWX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
YHH2_k127_1274377_1	998674.ATTE01000001_gene1888	2.405e-49	200.0	COG3386@1|root,COG4932@1|root,COG5184@1|root,COG3386@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,1NFXF@1224|Proteobacteria,1T5FG@1236|Gammaproteobacteria,4638P@72273|Thiotrichales	2|Bacteria	M	domain protein	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_2,CHU_C,Cna_B,Gram_pos_anchor,Laminin_G_3,Lectin_legB,MucBP,SLH,SdrD_B,VWA
YHH2_k127_1274377_2	404380.Gbem_3451	0.0001228	47.0	COG1215@1|root,COG1215@2|Bacteria,1NFA4@1224|Proteobacteria,42WEV@68525|delta/epsilon subdivisions,2WS1J@28221|Deltaproteobacteria,43U0R@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
YHH2_k127_1281484_1	497964.CfE428DRAFT_2602	1.274e-125	419.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
YHH2_k127_1281484_2	497964.CfE428DRAFT_6105	1.451e-73	261.0	COG1235@1|root,COG1235@2|Bacteria,46SKU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
YHH2_k127_1281484_0	497964.CfE428DRAFT_5496	6.023e-202	666.0	COG0553@1|root,COG0553@2|Bacteria,46TSJ@74201|Verrucomicrobia	74201|Verrucomicrobia	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
YHH2_k127_1281484_4	1293047.CBMA010000020_gene1137	1.758e-16	87.0	COG0454@1|root,arCOG00844@2157|Archaea,2XXJ4@28890|Euryarchaeota,23VX4@183963|Halobacteria	183963|Halobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
YHH2_k127_1281484_3	1232410.KI421420_gene3156	1.115e-48	194.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,43T20@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
YHH2_k127_1319910_4	395961.Cyan7425_4660	3.023e-45	170.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,3KH6U@43988|Cyanothece	1117|Cyanobacteria	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
YHH2_k127_1319910_1	1232453.BAIF02000054_gene1201	1.038e-137	446.0	COG0407@1|root,COG0407@2|Bacteria,1V4YU@1239|Firmicutes,24KSS@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
YHH2_k127_1319910_3	909663.KI867150_gene2770	1.785e-61	232.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
YHH2_k127_1319910_0	272134.KB731324_gene1352	3.556e-225	724.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18,3.2.1.4	ko:K01179,ko:K01186	ko00500,ko00511,ko00600,ko01100,ko04142,map00500,map00511,map00600,map01100,map04142	-	R04018,R06200,R11307,R11308	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33,GH5,GH9	-	BNR_2,BNR_3,CelD_N,Dockerin_1,Glyco_hydro_9,Laminin_G_3
YHH2_k127_1319910_2	1123269.NX02_24210	1.326e-98	341.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2TRD1@28211|Alphaproteobacteria,2K0G7@204457|Sphingomonadales	204457|Sphingomonadales	M	Membrane bound O-acyl transferase, MBOAT family protein	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
YHH2_k127_1319910_5	1121957.ATVL01000009_gene1031	2.561e-12	70.0	COG1262@1|root,COG1262@2|Bacteria,4NFR2@976|Bacteroidetes,47KU9@768503|Cytophagia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	1.8.3.7	ko:K13444	ko04142,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
YHH2_k127_1332447_1	469596.HMPREF9488_00426	1.454e-111	374.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,3VPKE@526524|Erysipelotrichia	526524|Erysipelotrichia	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIC
YHH2_k127_1332447_0	1123277.KB893244_gene5166	3.801e-116	392.0	COG0399@1|root,COG0399@2|Bacteria,4NE4B@976|Bacteroidetes,47M1Z@768503|Cytophagia	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH2_k127_1332447_3	649638.Trad_0164	2.799e-53	194.0	COG0454@1|root,COG0456@2|Bacteria,1WJ43@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH2_k127_1332447_2	215803.DB30_7698	3.874e-96	342.0	COG5520@1|root,COG5520@2|Bacteria,1PEJ2@1224|Proteobacteria,439C4@68525|delta/epsilon subdivisions,2X4K8@28221|Deltaproteobacteria,2YZ6N@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 30 beta sandwich domain	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
YHH2_k127_1332447_5	1214101.BN159_1299	2.851e-17	92.0	COG3210@1|root,COG3210@2|Bacteria,2I4P8@201174|Actinobacteria	201174|Actinobacteria	U	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH2_k127_1332447_4	402777.KB235903_gene2405	1.491e-35	154.0	COG1361@1|root,COG2373@1|root,COG2931@1|root,COG4222@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG4222@2|Bacteria,1G4X1@1117|Cyanobacteria,1HAE3@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind
YHH2_k127_1342818_1	452637.Oter_4241	4.191e-63	233.0	COG0805@1|root,COG0805@2|Bacteria,46T26@74201|Verrucomicrobia,3K8EP@414999|Opitutae	414999|Opitutae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YHH2_k127_1342818_3	497964.CfE428DRAFT_6193	2.355e-06	56.0	2FCQS@1|root,344TZ@2|Bacteria,46W38@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1342818_2	880072.Desac_1280	1.705e-53	199.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MQGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YHH2_k127_1342818_0	1403819.BATR01000181_gene6235	5.843e-83	280.0	COG0162@1|root,COG0162@2|Bacteria,46UVG@74201|Verrucomicrobia,2ITSI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (W and Y)	-	-	-	-	-	-	-	-	-	-	-	-	S4,tRNA-synt_1b
YHH2_k127_1357343_3	478741.JAFS01000002_gene320	4.504e-38	153.0	COG1427@1|root,COG1427@2|Bacteria,46VTU@74201|Verrucomicrobia,37GM0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
YHH2_k127_1357343_0	1123325.JHUV01000012_gene1032	1.563e-112	377.0	COG1060@1|root,COG1060@2|Bacteria,2G3M7@200783|Aquificae	200783|Aquificae	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Radical_SAM
YHH2_k127_1357343_2	338966.Ppro_0290	9.841e-61	229.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2WK8E@28221|Deltaproteobacteria,43TYR@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
YHH2_k127_1357343_1	497964.CfE428DRAFT_6143	2.892e-62	219.0	COG0163@1|root,COG0163@2|Bacteria,46V9E@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
YHH2_k127_1357551_2	391038.Bphy_7610	1.255e-33	132.0	2DSZ1@1|root,33HZU@2|Bacteria,1PXZ0@1224|Proteobacteria,2WD9I@28216|Betaproteobacteria,1K9SN@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1357551_3	497964.CfE428DRAFT_3289	6.238e-21	94.0	COG3344@1|root,COG3344@2|Bacteria,46TQ6@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
YHH2_k127_1357551_0	237609.PSAKL28_31720	8.866e-276	867.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,1RZMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH2_k127_1357551_1	1403819.BATR01000196_gene6596	2.217e-89	302.0	COG3344@1|root,COG3344@2|Bacteria,46TQ6@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
YHH2_k127_1380586_2	1392490.JHZX01000001_gene201	3.901e-56	220.0	COG1572@1|root,COG2931@1|root,COG3211@1|root,COG3540@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3211@2|Bacteria,COG3540@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia	976|Bacteroidetes	Q	twin-arginine translocation pathway signal protein	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
YHH2_k127_1380586_1	761193.Runsl_4733	4.811e-76	264.0	2DZG0@1|root,32V9P@2|Bacteria,4NTFA@976|Bacteroidetes,47RQH@768503|Cytophagia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
YHH2_k127_1380586_3	471854.Dfer_1961	8.234e-30	129.0	COG4122@1|root,COG4122@2|Bacteria,4NPJQ@976|Bacteroidetes,47WE2@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
YHH2_k127_1380586_0	344747.PM8797T_03995	2.239e-233	735.0	COG0008@1|root,COG0008@2|Bacteria,2IYSE@203682|Planctomycetes	203682|Planctomycetes	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
YHH2_k127_1380586_4	1121405.dsmv_2663	0.0002377	46.0	COG0644@1|root,COG0644@2|Bacteria,1NRHS@1224|Proteobacteria,42Z9T@68525|delta/epsilon subdivisions,2WUMT@28221|Deltaproteobacteria,2MMGQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1388660_1	1107311.Q767_01615	5.555e-49	202.0	COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
YHH2_k127_1388660_3	1232410.KI421418_gene2408	1.159e-08	69.0	COG3507@1|root,COG4733@1|root,COG3507@2|Bacteria,COG4733@2|Bacteria,1RDH5@1224|Proteobacteria	1224|Proteobacteria	G	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1349
YHH2_k127_1388660_2	555779.Dthio_PD2731	1.249e-20	109.0	COG3266@1|root,COG3420@1|root,COG3266@2|Bacteria,COG3420@2|Bacteria,1NNA4@1224|Proteobacteria	1224|Proteobacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1388660_0	452637.Oter_2196	4.426e-72	249.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_139512_0	497964.CfE428DRAFT_3889	5.291e-128	417.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
YHH2_k127_139512_1	1156937.MFUM_90005	1.039e-97	334.0	COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia,37G4Q@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
YHH2_k127_139512_5	398767.Glov_1941	1.994e-13	72.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
YHH2_k127_139512_4	497964.CfE428DRAFT_3892	4.208e-14	78.0	COG1399@1|root,COG1399@2|Bacteria,46TBP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
YHH2_k127_139512_2	497964.CfE428DRAFT_3893	2.602e-56	200.0	COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YHH2_k127_139512_3	224911.27356207	8.571e-52	207.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria,3JQS3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	CHASE2	cyaD	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
YHH2_k127_139512_6	794903.OPIT5_25520	2.217e-06	58.0	COG4254@1|root,COG4254@2|Bacteria,46XWE@74201|Verrucomicrobia,3K8GN@414999|Opitutae	414999|Opitutae	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
YHH2_k127_139512_7	497964.CfE428DRAFT_2202	3.454e-06	57.0	COG3307@1|root,COG3307@2|Bacteria,46TC1@74201|Verrucomicrobia	74201|Verrucomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH2_k127_1440523_8	1166018.FAES_4190	9.413e-24	104.0	COG3356@1|root,COG3356@2|Bacteria,4NGDG@976|Bacteroidetes,47JVE@768503|Cytophagia	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
YHH2_k127_1440523_6	880070.Cycma_0098	7.828e-58	218.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	3.1.3.15	ko:K02347,ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	PHP
YHH2_k127_1440523_7	1123059.KB823011_gene1693	6.29e-32	130.0	COG4319@1|root,COG4319@2|Bacteria,1RDBF@1224|Proteobacteria,2U7AM@28211|Alphaproteobacteria,43Y3X@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
YHH2_k127_1440523_3	937774.TEQUI_0452	3.199e-129	434.0	COG0500@1|root,COG2021@1|root,COG2021@2|Bacteria,COG2226@2|Bacteria,1MVJV@1224|Proteobacteria,2VHU9@28216|Betaproteobacteria,3T1KJ@506|Alcaligenaceae	28216|Betaproteobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metXS	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
YHH2_k127_1440523_0	456442.Mboo_1994	4.294e-216	677.0	COG2873@1|root,arCOG00061@2157|Archaea,2XSWM@28890|Euryarchaeota,2N9AN@224756|Methanomicrobia	224756|Methanomicrobia	E	PFAM Cys Met metabolism	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
YHH2_k127_1440523_1	1403819.BATR01000087_gene2541	1.19e-154	495.0	COG0031@1|root,COG0031@2|Bacteria,46UMC@74201|Verrucomicrobia,2ITKD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH2_k127_1440523_10	497964.CfE428DRAFT_0281	4.129e-05	50.0	COG2866@1|root,COG2866@2|Bacteria,46SNX@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
YHH2_k127_1440523_5	1210884.HG799466_gene12669	5.65e-58	205.0	COG1959@1|root,COG1959@2|Bacteria,2J0DH@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH2_k127_1440523_4	595460.RRSWK_07140	7.868e-108	367.0	COG1520@1|root,COG1520@2|Bacteria,2IXSV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_1440523_9	330214.NIDE0660	5.971e-10	63.0	COG1373@1|root,COG1373@2|Bacteria,3J14P@40117|Nitrospirae	40117|Nitrospirae	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH2_k127_1458367_2	1396141.BATP01000034_gene4198	1.633e-21	98.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_1458367_4	1321775.HMPREF1980_00425	9.52e-14	87.0	COG3087@1|root,COG3211@1|root,COG3087@2|Bacteria,COG3211@2|Bacteria,2HSC4@201174|Actinobacteria,4D4W9@85005|Actinomycetales	201174|Actinobacteria	D	Fibrinogen-related domains (FReDs)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1458367_0	583355.Caka_1736	0.0	1115.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_1458367_1	378806.STAUR_1759	2.762e-28	136.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria	1224|Proteobacteria	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
YHH2_k127_1458367_3	1396141.BATP01000034_gene4198	2.663e-20	109.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_1494383_0	1304885.AUEY01000019_gene1169	1.044e-150	498.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
YHH2_k127_1494383_2	1380394.JADL01000008_gene3484	6.322e-27	113.0	COG2114@1|root,COG2114@2|Bacteria,1MY09@1224|Proteobacteria,2U2KA@28211|Alphaproteobacteria,2JX68@204441|Rhodospirillales	204441|Rhodospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YHH2_k127_1494383_1	1185876.BN8_04770	2.217e-63	224.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47K7H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_1510317_0	29486.NJ56_03445	1.106e-38	156.0	COG0697@1|root,COG0697@2|Bacteria,1MVGC@1224|Proteobacteria,1RMXB@1236|Gammaproteobacteria,41EAE@629|Yersinia	1236|Gammaproteobacteria	EG	EamA-like transporter family	yddG	GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015318,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	iBWG_1329.BWG_1294,iE2348C_1286.E2348C_1607,iECDH10B_1368.ECDH10B_1604,iECDH1ME8569_1439.ECDH1ME8569_1416,iECS88_1305.ECS88_1565,iEcDH1_1363.EcDH1_2175,iJO1366.b1473,iNRG857_1313.NRG857_07295,iSSON_1240.SSON_1651,iUMN146_1321.UM146_09675	EamA
YHH2_k127_1510317_1	633.DJ40_995	1.078e-15	88.0	COG0697@1|root,COG0697@2|Bacteria,1MXX1@1224|Proteobacteria,1RPRZ@1236|Gammaproteobacteria,41EUA@629|Yersinia	1236|Gammaproteobacteria	EG	Permease of the drug metabolite transporter (DMT) superfamily	yedA	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
YHH2_k127_1518416_1	1408473.JHXO01000001_gene1962	8.02e-120	393.0	COG0667@1|root,COG0667@2|Bacteria,4PPAM@976|Bacteroidetes,2G14T@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH2_k127_1518416_3	479435.Kfla_1032	2.639e-23	109.0	COG1670@1|root,COG1670@2|Bacteria,2GNYE@201174|Actinobacteria,4DS1G@85009|Propionibacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YHH2_k127_1518416_2	243231.GSU2102	2.906e-103	344.0	COG1180@1|root,COG1180@2|Bacteria,1QJHU@1224|Proteobacteria,42R2E@68525|delta/epsilon subdivisions,2WMYN@28221|Deltaproteobacteria,43W3T@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
YHH2_k127_1518416_0	243231.GSU2101	0.0	1045.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,43TNZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Glycine radical	-	-	2.3.1.54,4.1.99.11,4.3.99.4	ko:K00656,ko:K07540,ko:K20038	ko00620,ko00623,ko00640,ko00650,ko01100,ko01120,ko01220,map00620,map00623,map00640,map00650,map01100,map01120,map01220	M00418	R00212,R05598,R06987	RC00004,RC01181,RC01433,RC01434,RC02742,RC02833	ko00000,ko00001,ko00002,ko01000	-	-	-	Gly_radical,PFL-like
YHH2_k127_1520196_1	497964.CfE428DRAFT_1669	1.682e-63	223.0	COG0563@1|root,COG0563@2|Bacteria,46SW4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
YHH2_k127_1520196_4	706587.Desti_2842	4.187e-13	73.0	2EUYT@1|root,33NE0@2|Bacteria,1P79U@1224|Proteobacteria,432X2@68525|delta/epsilon subdivisions,2WXB8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1520196_0	443143.GM18_3718	4.092e-93	318.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43TH3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YHH2_k127_1520196_2	1382359.JIAL01000001_gene2207	2.051e-43	163.0	COG2905@1|root,COG2905@2|Bacteria,3Y5NG@57723|Acidobacteria,2JN0N@204432|Acidobacteriia	204432|Acidobacteriia	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YHH2_k127_1520196_3	1121087.AUCK01000011_gene2033	2.485e-37	149.0	COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,1ZBTV@1386|Bacillus	91061|Bacilli	OU	signal peptide peptidase SppA	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
YHH2_k127_1547663_5	452637.Oter_1456	1.21e-54	203.0	COG1538@1|root,COG1538@2|Bacteria,46TY1@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH2_k127_1547663_4	1167006.UWK_01069	1.617e-60	222.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,2MHPS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH2_k127_1547663_0	452637.Oter_1454	0.0	1368.0	COG0841@1|root,COG0841@2|Bacteria,46SER@74201|Verrucomicrobia	74201|Verrucomicrobia	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH2_k127_1547663_2	509635.N824_15295	6.147e-140	472.0	2DBGI@1|root,2Z94U@2|Bacteria,4NI4P@976|Bacteroidetes,1IVFE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1547663_1	502025.Hoch_4996	8.51e-189	599.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	lpdA-1	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH2_k127_1547663_3	382464.ABSI01000013_gene1700	6.179e-92	317.0	COG3437@1|root,COG3437@2|Bacteria,46UU1@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
YHH2_k127_1583473_2	1267535.KB906767_gene3407	1.301e-17	85.0	COG0697@1|root,2Z7ID@2|Bacteria,3Y8N8@57723|Acidobacteria,2JNIX@204432|Acidobacteriia	204432|Acidobacteriia	EG	L-rhamnose-proton symport protein (RhaT)	-	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
YHH2_k127_1583473_0	1499967.BAYZ01000032_gene1133	1.816e-180	574.0	COG0205@1|root,COG0205@2|Bacteria,2NP3J@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
YHH2_k127_1583473_1	1388763.O165_027420	1.932e-22	101.0	COG3093@1|root,COG3093@2|Bacteria,1NA48@1224|Proteobacteria,1SCJR@1236|Gammaproteobacteria,1YZ0A@136845|Pseudomonas putida group	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
YHH2_k127_1594105_8	1121035.AUCH01000017_gene2319	2.516e-29	124.0	COG0707@1|root,COG0707@2|Bacteria,1QU89@1224|Proteobacteria,2VKVF@28216|Betaproteobacteria,2KX6K@206389|Rhodocyclales	206389|Rhodocyclales	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,MGDG_synth
YHH2_k127_1594105_4	497964.CfE428DRAFT_0873	2.553e-84	286.0	COG0289@1|root,COG0289@2|Bacteria,46SPR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
YHH2_k127_1594105_3	478741.JAFS01000002_gene313	1.408e-112	371.0	COG0329@1|root,COG0329@2|Bacteria,46SDY@74201|Verrucomicrobia,37G2R@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YHH2_k127_1594105_2	794903.OPIT5_04180	1.204e-119	394.0	COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia,3K7F5@414999|Opitutae	414999|Opitutae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
YHH2_k127_1594105_9	698761.RTCIAT899_CH11410	1.309e-10	65.0	2ENFV@1|root,33G39@2|Bacteria,1NP5K@1224|Proteobacteria,2UJUH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1594105_1	317936.Nos7107_4863	6.34e-155	506.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1HQTX@1161|Nostocales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
YHH2_k127_1594105_7	189753.AXAS01000058_gene145	2.375e-36	142.0	COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,2U8N1@28211|Alphaproteobacteria,3JY5Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH2_k127_1594105_5	880073.Calab_1371	2.376e-78	270.0	COG0294@1|root,COG0294@2|Bacteria,2NNN7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
YHH2_k127_1594105_6	1396418.BATQ01000056_gene232	1.641e-63	227.0	COG1624@1|root,COG1624@2|Bacteria,46SSQ@74201|Verrucomicrobia,2IU56@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DisA bacterial checkpoint controller nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
YHH2_k127_1594105_0	497964.CfE428DRAFT_3032	9.359e-186	591.0	COG1109@1|root,COG1109@2|Bacteria,46SJ2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YHH2_k127_1612693_0	1170562.Cal6303_2739	5.507e-71	268.0	COG0520@1|root,COG1672@1|root,COG2319@1|root,COG0520@2|Bacteria,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HINJ@1161|Nostocales	1117|Cyanobacteria	L	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
YHH2_k127_1612693_1	794903.OPIT5_05925	3.298e-42	168.0	COG5464@1|root,COG5464@2|Bacteria	2|Bacteria	S	double-stranded DNA endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
YHH2_k127_1626746_4	1396418.BATQ01000024_gene5204	2.771e-24	109.0	COG0625@1|root,COG0625@2|Bacteria,46SQB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
YHH2_k127_1626746_0	338966.Ppro_2494	2.116e-145	473.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,43UHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
YHH2_k127_1626746_3	82654.Pse7367_1078	1.06e-25	115.0	COG0457@1|root,COG0457@2|Bacteria,1G5P9@1117|Cyanobacteria,1HB1F@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
YHH2_k127_1626746_1	406124.ACPC01000013_gene1000	4.706e-134	439.0	COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,1ZB9P@1386|Bacillus	91061|Bacilli	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU16090	ATP-grasp_2,Ligase_CoA
YHH2_k127_1626746_2	240016.ABIZ01000001_gene4686	3.781e-132	430.0	COG0074@1|root,COG0074@2|Bacteria,46TRM@74201|Verrucomicrobia,2ITVZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
YHH2_k127_1634888_1	1403819.BATR01000171_gene5860	4.579e-152	493.0	COG3291@1|root,COG3291@2|Bacteria,46UB0@74201|Verrucomicrobia,2IWPC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_1634888_3	1123508.JH636439_gene1628	6.341e-77	274.0	COG0673@1|root,COG0673@2|Bacteria,2IX0C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_1634888_7	1403819.BATR01000094_gene2950	1.259e-13	78.0	COG0291@1|root,COG0291@2|Bacteria,46TCI@74201|Verrucomicrobia,2IUW5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L35	-	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
YHH2_k127_1634888_4	794903.OPIT5_02620	1.095e-36	145.0	COG0292@1|root,COG0292@2|Bacteria,46SZW@74201|Verrucomicrobia,3K87I@414999|Opitutae	414999|Opitutae	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
YHH2_k127_1634888_2	452637.Oter_2356	5.495e-111	368.0	COG0016@1|root,COG0016@2|Bacteria,46S6R@74201|Verrucomicrobia,3K7U5@414999|Opitutae	414999|Opitutae	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YHH2_k127_1634888_0	1125863.JAFN01000001_gene1869	6.601e-209	675.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
YHH2_k127_1634888_5	56780.SYN_00753	2.146e-33	132.0	2CIE9@1|root,32S7U@2|Bacteria,1P112@1224|Proteobacteria,431TX@68525|delta/epsilon subdivisions,2WWP3@28221|Deltaproteobacteria,2MS3R@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
YHH2_k127_1634888_6	43989.cce_2351	9.62e-18	90.0	2BVGP@1|root,32QVG@2|Bacteria,1GGUG@1117|Cyanobacteria,3KI5P@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1670125_2	497964.CfE428DRAFT_5484	1.189e-66	232.0	COG0323@1|root,COG0323@2|Bacteria,46SG5@74201|Verrucomicrobia	74201|Verrucomicrobia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
YHH2_k127_1670125_1	452637.Oter_2739	4.002e-79	281.0	COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia,3K7I6@414999|Opitutae	414999|Opitutae	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
YHH2_k127_1670125_0	1382359.JIAL01000001_gene1021	1.375e-179	580.0	COG1574@1|root,COG1574@2|Bacteria,3Y2UF@57723|Acidobacteria,2JIRH@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YHH2_k127_1670125_3	1297742.A176_01438	4.231e-07	63.0	COG5373@1|root,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	Otg1	-	-	-	-	-	-	-	-	-	-	-	DUF2339,DUF4167
YHH2_k127_1681020_4	1122134.KB893650_gene1102	7.343e-50	184.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XIJ4@135619|Oceanospirillales	135619|Oceanospirillales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
YHH2_k127_1681020_2	497964.CfE428DRAFT_2305	1.113e-91	311.0	COG1692@1|root,COG1692@2|Bacteria,46SQ2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
YHH2_k127_1681020_1	497964.CfE428DRAFT_3322	2.076e-108	362.0	COG0715@1|root,COG0715@2|Bacteria,46U6U@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
YHH2_k127_1681020_3	56780.SYN_01023	5.68e-70	253.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,2MQH2@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
YHH2_k127_1681020_5	596151.DesfrDRAFT_3564	0.0003332	54.0	COG0457@1|root,COG0457@2|Bacteria,1NK18@1224|Proteobacteria,42SRA@68525|delta/epsilon subdivisions,2WPJQ@28221|Deltaproteobacteria,2MG6B@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
YHH2_k127_1681020_0	794903.OPIT5_19015	1.751e-154	504.0	COG0143@1|root,COG0143@2|Bacteria,46SCQ@74201|Verrucomicrobia,3K783@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
YHH2_k127_1713437_0	247490.KSU1_C0507	1.944e-33	144.0	COG1361@1|root,COG1361@2|Bacteria,2IY9X@203682|Planctomycetes	203682|Planctomycetes	M	60 kDa outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH2_k127_1713437_1	62928.azo2194	0.0003886	54.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,2KV0V@206389|Rhodocyclales	206389|Rhodocyclales	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
YHH2_k127_1741473_2	344747.PM8797T_29842	1.867e-16	83.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
YHH2_k127_1741473_1	1379698.RBG1_1C00001G1509	4.356e-61	230.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,SBBP
YHH2_k127_1741473_0	382464.ABSI01000013_gene1549	1.076e-251	841.0	COG2312@1|root,COG3211@1|root,COG2312@2|Bacteria,COG3211@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
YHH2_k127_1741473_3	314287.GB2207_03000	4.909e-06	61.0	COG2834@1|root,COG3391@1|root,COG3637@1|root,COG2834@2|Bacteria,COG3391@2|Bacteria,COG3637@2|Bacteria,1QWRQ@1224|Proteobacteria	1224|Proteobacteria	M	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Abhydrolase_3,Cadherin-like,Cadherin_3,TIG,VCBS
YHH2_k127_1756422_12	583355.Caka_1274	4.935e-31	123.0	COG0211@1|root,COG0211@2|Bacteria,46X4Y@74201|Verrucomicrobia,3K8A7@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YHH2_k127_1756422_13	1382356.JQMP01000003_gene1853	2.706e-28	116.0	COG0261@1|root,COG0261@2|Bacteria,2G72T@200795|Chloroflexi,27YJB@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
YHH2_k127_1756422_8	530564.Psta_3726	8.27e-53	198.0	COG0637@1|root,COG0637@2|Bacteria,2IZIM@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH2_k127_1756422_3	452637.Oter_3498	1.832e-125	414.0	COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,3K794@414999|Opitutae	414999|Opitutae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH2_k127_1756422_14	158189.SpiBuddy_2795	2.154e-22	98.0	COG0254@1|root,COG0254@2|Bacteria,2J93Z@203691|Spirochaetes	203691|Spirochaetes	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
YHH2_k127_1756422_15	530564.Psta_4082	0.0004787	53.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,2IYH3@203682|Planctomycetes	203682|Planctomycetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,SdrD_B
YHH2_k127_1756422_2	338969.Rfer_2881	1.951e-157	526.0	COG5492@1|root,COG5492@2|Bacteria,1QY8X@1224|Proteobacteria,2VJ6A@28216|Betaproteobacteria	28216|Betaproteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1756422_10	1123501.KB902277_gene863	7.863e-41	153.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,2UCR7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
YHH2_k127_1756422_11	204669.Acid345_2713	5.308e-33	136.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
YHH2_k127_1756422_7	204669.Acid345_2713	1.547e-53	196.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
YHH2_k127_1756422_6	211165.AJLN01000109_gene143	1.215e-62	220.0	COG1905@1|root,COG1905@2|Bacteria,1G54V@1117|Cyanobacteria,1JJZK@1189|Stigonemataceae	1117|Cyanobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	hoxE	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
YHH2_k127_1756422_0	211165.AJLN01000109_gene145	7.599e-254	792.0	COG1894@1|root,COG1894@2|Bacteria,1G2KY@1117|Cyanobacteria,1JKPW@1189|Stigonemataceae	1117|Cyanobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	hoxF	-	1.6.5.3	ko:K05587	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
YHH2_k127_1756422_4	1173024.KI912151_gene2195	8.901e-111	362.0	COG3383@1|root,COG3383@2|Bacteria,1G3GD@1117|Cyanobacteria,1JKM7@1189|Stigonemataceae	1117|Cyanobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	hoxU	-	1.6.5.3	ko:K05588	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_6,Fer4_9,NADH-G_4Fe-4S_3
YHH2_k127_1756422_5	313624.NSP_28050	6.892e-68	237.0	COG1941@1|root,COG1941@2|Bacteria,1G2I6@1117|Cyanobacteria,1HJ2T@1161|Nostocales	1117|Cyanobacteria	C	PFAM NADH ubiquinone oxidoreductase, 20	hoxY	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	iJN678.hoxY	Oxidored_q6
YHH2_k127_1756422_1	28072.Nos7524_1733	1.857e-233	734.0	COG3259@1|root,COG3259@2|Bacteria,1G1C8@1117|Cyanobacteria,1HMGB@1161|Nostocales	1117|Cyanobacteria	C	Coenzyme F420-reducing hydrogenase, alpha subunit	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	iJN678.hoxH	NiFeSe_Hases
YHH2_k127_1756422_9	96561.Dole_1704	3.282e-45	190.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1761124_2	452637.Oter_2229	3.397e-112	375.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
YHH2_k127_1761124_3	497964.CfE428DRAFT_4167	2.009e-77	265.0	COG1208@1|root,COG1208@2|Bacteria,46SP1@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YHH2_k127_1761124_0	497964.CfE428DRAFT_4653	1.567e-215	691.0	COG1199@1|root,COG1199@2|Bacteria,46SCS@74201|Verrucomicrobia	74201|Verrucomicrobia	L	SMART helicase c2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
YHH2_k127_1761124_1	497964.CfE428DRAFT_0160	3.505e-203	649.0	COG1657@1|root,COG1657@2|Bacteria,46UEC@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
YHH2_k127_1761124_6	497964.CfE428DRAFT_2349	7.121e-39	159.0	COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
YHH2_k127_1761124_5	667014.Thein_2172	1.959e-44	166.0	COG1327@1|root,COG1327@2|Bacteria,2GGU9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
YHH2_k127_1761124_4	13035.Dacsa_0485	1.901e-44	164.0	COG0537@1|root,COG0537@2|Bacteria,1G6R2@1117|Cyanobacteria	1117|Cyanobacteria	FG	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
YHH2_k127_1771665_0	1267533.KB906735_gene4670	5.971e-231	753.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
YHH2_k127_1771665_1	1047013.AQSP01000120_gene937	1.017e-177	564.0	COG4030@1|root,COG4030@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
YHH2_k127_1809135_2	1341181.FLJC2902T_15110	2.078e-75	289.0	COG3386@1|root,COG3386@2|Bacteria,4PKPT@976|Bacteroidetes,1IKDI@117743|Flavobacteriia,2P0DY@237|Flavobacterium	976|Bacteroidetes	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
YHH2_k127_1809135_4	102125.Xen7305DRAFT_00048450	8.721e-06	60.0	COG2133@1|root,COG2931@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,1G2CB@1117|Cyanobacteria,3VM5E@52604|Pleurocapsales	1117|Cyanobacteria	GQ	Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,Lectin_C
YHH2_k127_1809135_1	234267.Acid_4124	3.285e-92	344.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
YHH2_k127_1809135_0	452637.Oter_0312	9.202e-114	419.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
YHH2_k127_1809135_3	251221.35213566	1.887e-21	113.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1809135_5	1538295.JY96_19425	0.0006162	53.0	COG3210@1|root,COG3210@2|Bacteria,1PZNB@1224|Proteobacteria,2W438@28216|Betaproteobacteria	28216|Betaproteobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_1895747_2	481448.Minf_1278	4.407e-130	429.0	COG4122@1|root,COG4122@2|Bacteria,46TZ5@74201|Verrucomicrobia,37G77@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Pup-ligase protein	-	-	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
YHH2_k127_1895747_10	478741.JAFS01000002_gene101	1.941e-41	165.0	COG0638@1|root,COG0638@2|Bacteria,46VYB@74201|Verrucomicrobia,37GKJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Proteasome subunit	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
YHH2_k127_1895747_6	497964.CfE428DRAFT_3467	4.097e-68	240.0	COG0638@1|root,COG0638@2|Bacteria,46UC7@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Proteasome subunit	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
YHH2_k127_1895747_1	1156937.MFUM_60015	2.741e-156	509.0	COG4122@1|root,COG4122@2|Bacteria,46TEU@74201|Verrucomicrobia,37G25@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Pup-ligase protein	-	-	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
YHH2_k127_1895747_0	478741.JAFS01000002_gene105	2.279e-190	614.0	COG1222@1|root,COG1222@2|Bacteria,46UBC@74201|Verrucomicrobia,37GE5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Proteasomal ATPase OB/ID domain	-	-	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
YHH2_k127_1895747_4	1380387.JADM01000001_gene213	7.44e-84	286.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
YHH2_k127_1895747_9	1179778.PMM47T1_16033	5.056e-52	197.0	COG4641@1|root,COG4641@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
YHH2_k127_1895747_7	1397527.Q670_01270	4.452e-63	227.0	COG2327@1|root,COG2327@2|Bacteria,1R9BX@1224|Proteobacteria,1TKM8@1236|Gammaproteobacteria,1XPXH@135619|Oceanospirillales	135619|Oceanospirillales	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
YHH2_k127_1895747_3	1137799.GZ78_12260	9.863e-101	341.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,1RQE3@1236|Gammaproteobacteria,1XN6Q@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH2_k127_1895747_5	1123367.C666_04355	1.178e-69	246.0	COG0515@1|root,COG0515@2|Bacteria,1MXX9@1224|Proteobacteria,2VHSR@28216|Betaproteobacteria,2KVD9@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core	-	-	-	ko:K02848	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Kdo
YHH2_k127_1895747_13	1121097.JCM15093_283	1.494e-07	64.0	COG3642@1|root,COG3642@2|Bacteria,4NIJK@976|Bacteroidetes,2FPB2@200643|Bacteroidia,4AK9R@815|Bacteroidaceae	976|Bacteroidetes	T	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
YHH2_k127_1895747_11	1042876.PPS_0340	7.658e-19	98.0	COG0515@1|root,COG0515@2|Bacteria,1RAG3@1224|Proteobacteria,1S4BG@1236|Gammaproteobacteria,1YY25@136845|Pseudomonas putida group	1236|Gammaproteobacteria	KLT	PFAM lipopolysaccharide kinase	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
YHH2_k127_1895747_8	497964.CfE428DRAFT_0566	7.061e-62	218.0	COG0590@1|root,COG0590@2|Bacteria,46SZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
YHH2_k127_1895747_12	1142394.PSMK_31960	5.963e-09	58.0	COG1051@1|root,COG1051@2|Bacteria,2J1PQ@203682|Planctomycetes	203682|Planctomycetes	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YHH2_k127_1947582_0	1121904.ARBP01000052_gene3650	1.515e-24	118.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,Hydrolase_4
YHH2_k127_1949399_3	1961.JOAK01000022_gene7055	9.081e-25	124.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,2GKNI@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
YHH2_k127_1949399_5	1396141.BATP01000059_gene2520	8.149e-24	121.0	COG1404@1|root,COG2133@1|root,COG3055@1|root,COG3204@1|root,COG3506@1|root,COG3897@1|root,COG4733@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3506@2|Bacteria,COG3897@2|Bacteria,COG4733@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	1.11.1.5,3.1.3.8,4.2.2.2	ko:K00428,ko:K01083,ko:K01728	ko00040,ko00562,ko02024,map00040,map00562,map02024	-	R02361,R03371,R06240	RC00049,RC00078,RC00705	ko00000,ko00001,ko01000	-	-	-	GSDH,Laminin_G_3,Malectin
YHH2_k127_1949399_2	497964.CfE428DRAFT_0397	6.515e-27	131.0	COG2755@1|root,COG2931@1|root,COG3210@1|root,COG3391@1|root,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.2.1.4,4.2.2.3	ko:K01179,ko:K01729,ko:K09942	ko00051,ko00500,ko01100,map00051,map00500,map01100	-	R03706,R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	SLH
YHH2_k127_1949399_7	1396141.BATP01000022_gene455	1.503e-16	97.0	COG4675@1|root,COG4675@2|Bacteria,46X85@74201|Verrucomicrobia,2IUYY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
YHH2_k127_1949399_0	1268622.AVS7_04453	2.711e-157	562.0	COG3637@1|root,COG5563@1|root,COG3637@2|Bacteria,COG5563@2|Bacteria,1QVUE@1224|Proteobacteria	1224|Proteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	fn3
YHH2_k127_1949399_4	1278073.MYSTI_05030	2.72e-24	123.0	COG3055@1|root,COG5563@1|root,COG3055@2|Bacteria,COG5563@2|Bacteria,1QE0Q@1224|Proteobacteria,4318S@68525|delta/epsilon subdivisions,2WX4P@28221|Deltaproteobacteria,2YYIK@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,Glyoxal_oxid_N,Kelch_1
YHH2_k127_1949399_6	521674.Plim_1564	6.888e-22	111.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,2IXK7@203682|Planctomycetes	203682|Planctomycetes	C	TIGRFAM membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
YHH2_k127_1949399_1	357276.EL88_00435	1.046e-81	295.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,2FNB7@200643|Bacteroidia,4AM78@815|Bacteroidaceae	976|Bacteroidetes	O	COG NOG08360 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
YHH2_k127_1950670_1	945713.IALB_1186	3.98e-173	559.0	COG5368@1|root,COG5368@2|Bacteria	2|Bacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3131,Glycoamylase
YHH2_k127_1950670_0	1380394.JADL01000003_gene4962	4.389e-213	691.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
YHH2_k127_1950670_3	497964.CfE428DRAFT_3384	2.82e-127	417.0	COG0207@1|root,COG0207@2|Bacteria,46SCY@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
YHH2_k127_1950670_5	583355.Caka_1328	6.708e-48	176.0	COG0262@1|root,COG0262@2|Bacteria,46X6E@74201|Verrucomicrobia,3K9WI@414999|Opitutae	414999|Opitutae	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
YHH2_k127_1950670_4	1123508.JH636448_gene7526	1.869e-79	271.0	COG0434@1|root,COG0434@2|Bacteria	2|Bacteria	S	BtpA family	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
YHH2_k127_1950670_2	497964.CfE428DRAFT_6515	1.517e-152	509.0	COG0457@1|root,COG0457@2|Bacteria,46UKC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	FAT,Peptidase_C39_2
YHH2_k127_1956788_1	547045.NEISICOT_03300	1.412e-52	200.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KQPW@206351|Neisseriales	206351|Neisseriales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
YHH2_k127_1956788_0	595460.RRSWK_00052	1.369e-141	460.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,F5_F8_type_C,Glyco_hydro_28
YHH2_k127_1956788_2	595460.RRSWK_00052	1.964e-29	125.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,F5_F8_type_C,Glyco_hydro_28
YHH2_k127_1979591_2	1235803.C825_01882	2.416e-104	361.0	COG5434@1|root,COG5434@2|Bacteria,4NIEA@976|Bacteroidetes,2FMVC@200643|Bacteroidia	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH2_k127_1979591_3	1047013.AQSP01000120_gene949	3.07e-57	210.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_1979591_1	861299.J421_6019	9.875e-181	578.0	COG0531@1|root,COG0531@2|Bacteria,1ZSQW@142182|Gemmatimonadetes	2|Bacteria	E	Amino acid permease	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
YHH2_k127_1979591_0	314230.DSM3645_04495	4.832e-212	687.0	COG0591@1|root,COG3055@1|root,COG0591@2|Bacteria,COG3055@2|Bacteria,2IX6M@203682|Planctomycetes	203682|Planctomycetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,SSF
YHH2_k127_2004775_1	661478.OP10G_1344	1.73e-115	392.0	COG4030@1|root,COG4733@1|root,COG4030@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
YHH2_k127_2004775_0	160799.PBOR_30720	4.461e-134	456.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HF4F@91061|Bacilli,26VTM@186822|Paenibacillaceae	91061|Bacilli	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
YHH2_k127_2004775_2	493475.GARC_3401	5.118e-80	291.0	COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,1S0S6@1236|Gammaproteobacteria,46A7Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH2_k127_2063974_2	471854.Dfer_4490	1.357e-109	367.0	COG1520@1|root,COG1520@2|Bacteria,4NK4X@976|Bacteroidetes,47KWI@768503|Cytophagia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2063974_1	1340493.JNIF01000003_gene3009	1.965e-130	431.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Oxidoreduct_C,PmoA
YHH2_k127_2063974_0	452637.Oter_2235	6.644e-180	574.0	COG0460@1|root,COG0460@2|Bacteria,46TFC@74201|Verrucomicrobia,3K7MC@414999|Opitutae	414999|Opitutae	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
YHH2_k127_2090550_0	497964.CfE428DRAFT_4368	4.482e-92	324.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,PQQ_2,PQQ_3
YHH2_k127_2125164_0	583355.Caka_0996	8.965e-167	544.0	COG3537@1|root,COG3537@2|Bacteria	2|Bacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,Glyco_hydro_85,PA14
YHH2_k127_2125164_2	595460.RRSWK_00696	1.595e-08	62.0	COG5126@1|root,COG5126@2|Bacteria,2J3TS@203682|Planctomycetes	203682|Planctomycetes	DTZ	EF-hand, calcium binding motif	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
YHH2_k127_2127970_1	344747.PM8797T_06847	1.007e-229	731.0	COG0657@1|root,COG3458@1|root,COG0657@2|Bacteria,COG3458@2|Bacteria,2J1TC@203682|Planctomycetes	203682|Planctomycetes	Q	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2127970_6	452637.Oter_0986	5.86e-15	87.0	2AXAG@1|root,31P9J@2|Bacteria,46XVM@74201|Verrucomicrobia,3K8EC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2127970_2	1303518.CCALI_02577	7.657e-181	578.0	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
YHH2_k127_2127970_3	1131269.AQVV01000050_gene418	2.899e-129	421.0	COG2107@1|root,COG2107@2|Bacteria	2|Bacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K07083,ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
YHH2_k127_2127970_4	1173027.Mic7113_6244	3.59e-100	339.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G1M7@1117|Cyanobacteria,1H7YE@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_2127970_5	583355.Caka_1736	1.411e-83	318.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_2127970_0	1396141.BATP01000034_gene4198	3.273e-267	895.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_2151229_0	1403819.BATR01000164_gene5581	1.183e-79	278.0	COG0329@1|root,COG0329@2|Bacteria,46UHJ@74201|Verrucomicrobia,2IU2T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EM	Dihydrodipicolinate synthetase family	-	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
YHH2_k127_2151229_1	1116472.MGMO_8c00230	8.209e-46	188.0	COG3391@1|root,COG5563@1|root,COG3391@2|Bacteria,COG5563@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466,VPEP
YHH2_k127_2151229_2	1123508.JH636443_gene4591	4.24e-39	166.0	COG1073@1|root,COG1073@2|Bacteria,2IXK0@203682|Planctomycetes	203682|Planctomycetes	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
YHH2_k127_2162249_3	1116472.MGMO_17c00160	2.709e-20	109.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1RC5K@1224|Proteobacteria,1S3I9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH2_k127_2162249_2	1396141.BATP01000060_gene4765	2.058e-20	109.0	COG0028@1|root,COG2730@1|root,COG2755@1|root,COG2931@1|root,COG3506@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG0028@2|Bacteria,COG2730@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3506@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
YHH2_k127_2162249_1	1396141.BATP01000059_gene2520	3.141e-24	122.0	COG1404@1|root,COG2133@1|root,COG3055@1|root,COG3204@1|root,COG3506@1|root,COG3897@1|root,COG4733@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3506@2|Bacteria,COG3897@2|Bacteria,COG4733@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	1.11.1.5,3.1.3.8,4.2.2.2	ko:K00428,ko:K01083,ko:K01728	ko00040,ko00562,ko02024,map00040,map00562,map02024	-	R02361,R03371,R06240	RC00049,RC00078,RC00705	ko00000,ko00001,ko01000	-	-	-	GSDH,Laminin_G_3,Malectin
YHH2_k127_2162249_4	452637.Oter_0312	3.933e-08	68.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
YHH2_k127_2162249_0	452637.Oter_4612	2.652e-25	125.0	COG5549@1|root,COG5549@2|Bacteria,46UKP@74201|Verrucomicrobia,3KA3E@414999|Opitutae	2|Bacteria	O	Immunoglobulin I-set domain protein	-	-	3.2.1.4,3.4.24.40	ko:K01179,ko:K01406	ko00500,ko01100,ko01503,map00500,map01100,map01503	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002	-	GH5,GH9	-	CBM60,DUF4214,Glyco_hydro_16,HemolysinCabind,Peptidase_M10,Peptidase_M10_C,Reprolysin_4,W_rich_C
YHH2_k127_2162300_2	583355.Caka_0018	2.322e-81	282.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	414999|Opitutae	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
YHH2_k127_2162300_1	583355.Caka_0017	5.117e-83	280.0	COG3880@1|root,COG3880@2|Bacteria,46SMN@74201|Verrucomicrobia,3K7MX@414999|Opitutae	414999|Opitutae	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
YHH2_k127_2162300_0	452637.Oter_3299	2.505e-130	435.0	COG1055@1|root,COG1055@2|Bacteria,46S6A@74201|Verrucomicrobia,3K7TN@414999|Opitutae	414999|Opitutae	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
YHH2_k127_2162300_3	1123508.JH636448_gene7659	3.139e-60	215.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
YHH2_k127_2162300_4	234267.Acid_2554	3.254e-17	91.0	COG3344@1|root,COG3344@2|Bacteria	2|Bacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
YHH2_k127_2175472_1	96561.Dole_2050	0.0001377	52.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42Q3J@68525|delta/epsilon subdivisions,2WP5U@28221|Deltaproteobacteria,2MKDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,YwqJ-deaminase
YHH2_k127_2175472_0	195250.CM001776_gene961	4.227e-77	278.0	COG0358@1|root,COG0358@2|Bacteria	2|Bacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_N,zf-CHC2
YHH2_k127_2209397_0	794903.OPIT5_16410	2.863e-218	688.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia,3K7EV@414999|Opitutae	414999|Opitutae	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
YHH2_k127_2209397_8	665571.STHERM_c21880	4.661e-06	55.0	COG2201@1|root,COG2201@2|Bacteria,2J62V@203691|Spirochaetes	203691|Spirochaetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
YHH2_k127_2209397_3	96561.Dole_2139	4.607e-66	250.0	COG1520@1|root,COG3325@1|root,COG4870@1|root,COG1520@2|Bacteria,COG3325@2|Bacteria,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	DUF1863,DUF4849,PQQ_2,PQQ_3
YHH2_k127_2209397_5	580332.Slit_1815	1.737e-12	74.0	2DQ3J@1|root,334KB@2|Bacteria,1NFUT@1224|Proteobacteria,2WFRE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2209397_2	351160.RRC213	1.957e-72	278.0	COG3391@1|root,arCOG02544@1|root,arCOG02544@2157|Archaea,arCOG02562@2157|Archaea,2Y7T2@28890|Euryarchaeota,2NBM7@224756|Methanomicrobia	224756|Methanomicrobia	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
YHH2_k127_2209397_6	697282.Mettu_2044	1.88e-11	70.0	2DQ3J@1|root,334KB@2|Bacteria,1NFUT@1224|Proteobacteria,1SH2X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2209397_7	1122609.AUGT01000009_gene3207	9.621e-08	65.0	COG1404@1|root,COG1470@1|root,COG2373@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,COG2373@2|Bacteria,2HQ9W@201174|Actinobacteria,4DRST@85009|Propionibacteriales	201174|Actinobacteria	MO	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2209397_4	1278309.KB907099_gene2910	3.322e-45	184.0	COG2132@1|root,COG3828@1|root,COG2132@2|Bacteria,COG3828@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
YHH2_k127_2209397_1	1123518.ARWI01000001_gene1640	3.006e-80	276.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
YHH2_k127_2218765_0	1282360.ABAC460_05240	2.7e-05	57.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,2TU30@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0110 Acetyltransferase (isoleucine patch superfamily	cat	-	2.3.1.28	ko:K00638,ko:K18234	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Hexapep
YHH2_k127_2225941_2	1379270.AUXF01000007_gene950	1.534e-53	196.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1ZU8B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome b/b6/petB	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_CBB3
YHH2_k127_2225941_6	1165841.SULAR_01175	7.718e-43	164.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,42TZV@68525|delta/epsilon subdivisions,2YR1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
YHH2_k127_2225941_7	864702.OsccyDRAFT_2137	9.227e-43	180.0	COG0823@1|root,COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4655@1|root,COG0823@2|Bacteria,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4655@2|Bacteria,1G0DX@1117|Cyanobacteria,1H8AY@1150|Oscillatoriales	1117|Cyanobacteria	Q	COG2931 RTX toxins and related Ca2 -binding	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF11,DUF4347,HemolysinCabind,Laminin_G_3,VCBS
YHH2_k127_2225941_9	1396141.BATP01000021_gene179	2.683e-07	64.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,PQQ_2
YHH2_k127_2225941_8	497964.CfE428DRAFT_5963	4e-10	71.0	2F7AY@1|root,33ZS4@2|Bacteria,46VZW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2225941_10	305700.B447_05128	6.674e-06	55.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,2KWCY@206389|Rhodocyclales	206389|Rhodocyclales	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	HSCB_C
YHH2_k127_2225941_5	240016.ABIZ01000001_gene5092	2.261e-43	164.0	COG0316@1|root,COG0316@2|Bacteria,46T1T@74201|Verrucomicrobia,2IUGI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
YHH2_k127_2225941_0	1121904.ARBP01000026_gene688	5.057e-155	496.0	COG0620@1|root,COG0620@2|Bacteria,4NF5S@976|Bacteroidetes,47NU3@768503|Cytophagia	976|Bacteroidetes	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
YHH2_k127_2225941_1	1089547.KB913013_gene2812	8.375e-113	371.0	COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes,47MJI@768503|Cytophagia	976|Bacteroidetes	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
YHH2_k127_2225941_3	497964.CfE428DRAFT_0979	3.254e-51	186.0	COG0735@1|root,COG0735@2|Bacteria,46V9Y@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH2_k127_2225941_4	1403819.BATR01000123_gene4356	5.775e-51	191.0	28KDQ@1|root,2ZA05@2|Bacteria,46VJS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2236213_3	314260.PB2503_01972	2.198e-08	61.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_2236213_0	1403819.BATR01000191_gene6474	5.734e-110	365.0	COG2115@1|root,COG2115@2|Bacteria	2|Bacteria	G	xylose isomerase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH2_k127_2236213_2	497964.CfE428DRAFT_6227	5.455e-71	251.0	COG0676@1|root,COG0676@2|Bacteria,46VKE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Aldose 1-epimerase	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
YHH2_k127_2236213_1	1123508.JH636440_gene2700	8.005e-80	273.0	COG1878@1|root,COG1878@2|Bacteria,2J1IQ@203682|Planctomycetes	203682|Planctomycetes	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
YHH2_k127_2287811_1	65672.G4TP14	4.149e-27	130.0	KOG4155@1|root,KOG4155@2759|Eukaryota,3AG0Y@33154|Opisthokonta,3Q4RG@4751|Fungi,3V38M@5204|Basidiomycota,22FDX@155619|Agaricomycetes,3H92M@355688|Agaricomycetes incertae sedis	4751|Fungi	S	WD40 repeat-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NACHT,WD40
YHH2_k127_2287811_0	661478.OP10G_4327	8.179e-262	821.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,DUF4038,DUF5060,F5_F8_type_C,Glyco_hydro_81
YHH2_k127_2342484_1	452637.Oter_4174	1.403e-55	199.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YHH2_k127_2342484_0	886293.Sinac_7479	1.743e-120	418.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
YHH2_k127_2342600_0	886293.Sinac_6489	8.505e-122	423.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
YHH2_k127_2344278_4	452637.Oter_0753	8.717e-70	244.0	COG0651@1|root,COG0651@2|Bacteria,46U4G@74201|Verrucomicrobia,3K7M3@414999|Opitutae	2|Bacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	ndhD5	-	1.6.5.3	ko:K05568,ko:K05575	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2	-	iJN678.ndhD	Proton_antipo_M
YHH2_k127_2344278_0	452637.Oter_0751	5.507e-225	706.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	nuoL2	-	1.6.5.3	ko:K00341,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
YHH2_k127_2344278_9	452637.Oter_0750	3.725e-39	149.0	COG0713@1|root,COG0713@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YHH2_k127_2344278_8	452637.Oter_0749	1.009e-42	164.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YHH2_k127_2344278_7	452637.Oter_0748	6.689e-44	164.0	COG1143@1|root,COG1143@2|Bacteria,46YB4@74201|Verrucomicrobia,3K98S@414999|Opitutae	414999|Opitutae	C	4Fe-4S binding domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
YHH2_k127_2344278_2	452637.Oter_0747	1.757e-146	470.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,3K82N@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH2_k127_2344278_1	452637.Oter_0746	8.718e-185	584.0	COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,3K8K5@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
YHH2_k127_2344278_5	452637.Oter_0745	2.659e-57	209.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
YHH2_k127_2344278_3	452637.Oter_0744	8.296e-89	294.0	COG0377@1|root,COG0377@2|Bacteria,46YVB@74201|Verrucomicrobia,3K85T@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YHH2_k127_2344278_6	452637.Oter_0743	2.374e-51	187.0	COG0838@1|root,COG0838@2|Bacteria,46XVA@74201|Verrucomicrobia,3K8I9@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YHH2_k127_2347798_0	497964.CfE428DRAFT_3513	2.821e-33	134.0	COG0684@1|root,COG0684@2|Bacteria,46SB3@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
YHH2_k127_2347798_1	1313172.YM304_35140	3.134e-27	129.0	COG3420@1|root,COG3420@2|Bacteria,2I9HA@201174|Actinobacteria	201174|Actinobacteria	P	Right handed beta helix region	wcoB	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
YHH2_k127_2352306_1	56780.SYN_03243	8.275e-112	372.0	COG1693@1|root,COG1693@2|Bacteria,1RAC2@1224|Proteobacteria,42QW9@68525|delta/epsilon subdivisions,2WMZV@28221|Deltaproteobacteria,2MQWZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Ribonuclease R winged-helix domain	-	-	-	ko:K09720	-	-	-	-	ko00000,ko03000	-	-	-	DUF128,HTH_12
YHH2_k127_2352306_3	1047013.AQSP01000092_gene317	6.235e-60	214.0	COG0778@1|root,COG0778@2|Bacteria,2NR7M@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YHH2_k127_2352306_0	335543.Sfum_1617	1.805e-115	392.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YHH2_k127_2352306_2	261292.Nit79A3_0736	4.96e-79	278.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,371PB@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
YHH2_k127_2367806_1	1396418.BATQ01000163_gene2011	2.536e-100	337.0	COG0673@1|root,COG0673@2|Bacteria,46TKX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_2367806_0	504472.Slin_6275	1.656e-103	344.0	COG2220@1|root,COG2220@2|Bacteria,4PJJ0@976|Bacteroidetes,47NNW@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
YHH2_k127_2367806_2	179408.Osc7112_4148	1.554e-99	335.0	COG1408@1|root,COG1408@2|Bacteria,1GQUH@1117|Cyanobacteria,1HAMV@1150|Oscillatoriales	1117|Cyanobacteria	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_245951_4	489825.LYNGBM3L_21710	4.151e-98	340.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,1G0A1@1117|Cyanobacteria,1H7JR@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
YHH2_k127_245951_8	883.DvMF_2540	1.663e-50	184.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42T9C@68525|delta/epsilon subdivisions,2WP3Z@28221|Deltaproteobacteria,2MCRS@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH2_k127_245951_7	1279038.KB907339_gene1260	1.369e-52	192.0	COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,2U7MF@28211|Alphaproteobacteria,2JSI8@204441|Rhodospirillales	204441|Rhodospirillales	T	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH2_k127_245951_5	1121438.JNJA01000008_gene3997	5.999e-97	340.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42RAK@68525|delta/epsilon subdivisions,2WMP9@28221|Deltaproteobacteria,2MB8A@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4
YHH2_k127_245951_1	497964.CfE428DRAFT_6231	2.163e-205	666.0	COG0745@1|root,COG5000@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,46S9G@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
YHH2_k127_245951_9	398767.Glov_2434	7.405e-33	132.0	COG0745@1|root,COG0745@2|Bacteria	398767.Glov_2434|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_245951_3	429009.Adeg_0221	2.858e-122	398.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,42F8X@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YHH2_k127_245951_6	497964.CfE428DRAFT_3441	3.068e-54	195.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM UvrB UvrC protein	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
YHH2_k127_245951_2	497964.CfE428DRAFT_3440	1.144e-135	441.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Protein-arginine kinase	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
YHH2_k127_245951_0	1403819.BATR01000066_gene1968	0.0	1180.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,2ITPB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YHH2_k127_246119_1	1423321.AS29_20880	9.512e-28	131.0	COG5434@1|root,COG5434@2|Bacteria,1UHQG@1239|Firmicutes,4HI8W@91061|Bacilli,1ZSFJ@1386|Bacillus	91061|Bacilli	M	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
YHH2_k127_2525307_0	935845.JADQ01000029_gene1230	1.433e-70	252.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
YHH2_k127_2525307_1	313612.L8106_17667	1.718e-49	200.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7FN@1150|Oscillatoriales	1117|Cyanobacteria	KLT	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
YHH2_k127_255950_0	452637.Oter_0123	1.523e-179	586.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	safC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
YHH2_k127_2563679_3	583355.Caka_2052	6.604e-63	229.0	COG1943@1|root,COG1943@2|Bacteria,46V7I@74201|Verrucomicrobia,3K8VX@414999|Opitutae	414999|Opitutae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH2_k127_2563679_5	1033743.CAES01000033_gene1061	1.405e-31	135.0	COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,4HC5R@91061|Bacilli,26WUY@186822|Paenibacillaceae	91061|Bacilli	E	D-aminopeptidase	dppA	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
YHH2_k127_2563679_2	400668.Mmwyl1_0657	3.782e-68	252.0	COG0457@1|root,COG0457@2|Bacteria,1RCNU@1224|Proteobacteria,1S2R5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
YHH2_k127_2563679_0	29581.BW37_02044	1.774e-110	382.0	COG0840@1|root,COG4191@1|root,COG0840@2|Bacteria,COG4191@2|Bacteria,1NC2U@1224|Proteobacteria,2VS77@28216|Betaproteobacteria,476KI@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Response_reg
YHH2_k127_2563679_1	1379270.AUXF01000003_gene3853	2.738e-101	348.0	COG0591@1|root,COG0591@2|Bacteria,1ZTEB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH2_k127_2563679_7	1173029.JH980292_gene1283	1.271e-05	50.0	COG2026@1|root,COG2026@2|Bacteria,1G9CX@1117|Cyanobacteria,1HDD1@1150|Oscillatoriales	1117|Cyanobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
YHH2_k127_2563679_4	344747.PM8797T_13807	1.694e-51	195.0	COG1136@1|root,COG1136@2|Bacteria,2J1YS@203682|Planctomycetes	203682|Planctomycetes	V	COG1136 ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH2_k127_2563679_6	344747.PM8797T_31648	3.71e-31	125.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	tagS	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_2590773_0	497964.CfE428DRAFT_1213	3.868e-95	323.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	DUF4388,HATPase_c,HTH_8,HisKA,Response_reg,SSF,Sigma54_activat
YHH2_k127_2590773_1	497964.CfE428DRAFT_6252	1.382e-85	290.0	COG1968@1|root,COG1968@2|Bacteria,46SP6@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
YHH2_k127_2590773_5	344747.PM8797T_31795	1.138e-07	59.0	COG5126@1|root,COG5126@2|Bacteria,2J41T@203682|Planctomycetes	203682|Planctomycetes	DTZ	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
YHH2_k127_2590773_2	1396418.BATQ01000135_gene3650	8.185e-38	154.0	COG2165@1|root,COG2165@2|Bacteria,46W6U@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH2_k127_2606739_2	1123242.JH636434_gene3671	1.043e-125	407.0	COG2133@1|root,COG2133@2|Bacteria,2IXUJ@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH2_k127_2606739_4	497964.CfE428DRAFT_4323	5.884e-86	292.0	COG1082@1|root,COG1082@2|Bacteria,46V2Z@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_2606739_5	497964.CfE428DRAFT_4321	1.526e-64	226.0	COG4154@1|root,COG4154@2|Bacteria	2|Bacteria	G	fucose binding	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
YHH2_k127_2606739_0	497964.CfE428DRAFT_4319	8.258e-158	502.0	COG0667@1|root,COG0667@2|Bacteria,46SC7@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM aldo keto reductase	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
YHH2_k127_2606739_1	497964.CfE428DRAFT_4318	6.818e-149	479.0	COG1063@1|root,COG1063@2|Bacteria,46TQ3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Alcohol dehydrogenase GroES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YHH2_k127_2606739_3	1121904.ARBP01000003_gene6192	9.038e-101	337.0	COG3618@1|root,COG3618@2|Bacteria,4NFGB@976|Bacteroidetes,47JKH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Amidohydrolase 2	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
YHH2_k127_2606739_6	929713.NIASO_16410	3.204e-35	135.0	COG0251@1|root,COG0251@2|Bacteria,4NMAM@976|Bacteroidetes,1IS1P@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
YHH2_k127_2619898_4	643867.Ftrac_1357	5.795e-07	61.0	COG2353@1|root,COG3210@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes,47TZD@768503|Cytophagia	976|Bacteroidetes	U	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2619898_0	1340493.JNIF01000004_gene602	8.726e-186	595.0	COG0823@1|root,COG0823@2|Bacteria,3Y6DB@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH2_k127_2619898_3	794903.OPIT5_09090	6.426e-16	89.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.4.1.21	ko:K00703,ko:K07082	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	AAA_12,DUF559,PGA_cap,WG_beta_rep
YHH2_k127_2619898_2	1168034.FH5T_03995	1.383e-38	149.0	2A42S@1|root,30SMP@2|Bacteria	2|Bacteria	S	Nickel-containing superoxide dismutase	-	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
YHH2_k127_2619898_1	395963.Bind_2111	2.329e-111	373.0	COG2017@1|root,COG2017@2|Bacteria,1MVUY@1224|Proteobacteria,2U3XD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
YHH2_k127_2626517_0	448385.sce3157	7.415e-255	801.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	GATase,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YHH2_k127_2626517_1	497964.CfE428DRAFT_4579	2.672e-215	682.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YHH2_k127_2626517_4	497964.CfE428DRAFT_4578	1.686e-39	151.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN3	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
YHH2_k127_2626517_2	452637.Oter_1576	4.953e-84	289.0	COG0598@1|root,COG0598@2|Bacteria,46VYH@74201|Verrucomicrobia,3K7J8@414999|Opitutae	414999|Opitutae	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YHH2_k127_2626517_3	478741.JAFS01000002_gene392	3.263e-51	188.0	COG5000@1|root,COG5000@2|Bacteria,46S9Q@74201|Verrucomicrobia,37FXN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	PAS domain	ntrB	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
YHH2_k127_2659213_1	314230.DSM3645_23076	2.495e-117	392.0	COG1520@1|root,COG1520@2|Bacteria,2IXN8@203682|Planctomycetes	203682|Planctomycetes	S	serine threonine protein kinase afsK	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YHH2_k127_2659213_0	313628.LNTAR_23084	3.885e-210	687.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
YHH2_k127_2721149_3	755732.Fluta_1212	7.786e-42	179.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1I0BV@117743|Flavobacteriia	976|Bacteroidetes	M	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
YHH2_k127_2721149_6	1121007.AUML01000038_gene2075	2.909e-07	65.0	COG3325@1|root,COG3469@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3469@2|Bacteria,COG3979@2|Bacteria,4PKBR@976|Bacteroidetes	976|Bacteroidetes	G	Glycoside Hydrolase	-	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,CarboxypepD_reg,Glyco_hydro_18
YHH2_k127_2721149_5	1229780.BN381_330104	1.224e-12	83.0	COG3211@1|root,COG3211@2|Bacteria	2|Bacteria	O	Phosphatase	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839,PD40
YHH2_k127_2721149_0	1403819.BATR01000185_gene6430	5.272e-117	421.0	COG3121@1|root,COG3204@1|root,COG3291@1|root,COG3506@1|root,COG5184@1|root,COG3121@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
YHH2_k127_2721149_1	105559.Nwat_2827	5.218e-106	370.0	COG5298@1|root,COG5298@2|Bacteria,1MYMJ@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2334)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334
YHH2_k127_2721149_8	332101.JIBU02000013_gene1351	7.336e-05	56.0	COG1361@1|root,COG1572@1|root,COG2247@1|root,COG2374@1|root,COG3386@1|root,COG4447@1|root,COG5492@1|root,COG1361@2|Bacteria,COG1572@2|Bacteria,COG2247@2|Bacteria,COG2374@2|Bacteria,COG3386@2|Bacteria,COG4447@2|Bacteria,COG5492@2|Bacteria,1V3RT@1239|Firmicutes,25BDG@186801|Clostridia,36WE8@31979|Clostridiaceae	1239|Firmicutes	MN	Carbohydrate binding domain X2	-	-	-	-	-	-	-	-	-	-	-	-	CBM_X2,CW_binding_2,Cadherin-like,Laminin_G_3,SLH
YHH2_k127_2721149_2	909663.KI867150_gene711	3.361e-75	259.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,43A29@68525|delta/epsilon subdivisions,2X21K@28221|Deltaproteobacteria,2MS4J@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
YHH2_k127_2721149_4	1120965.AUBV01000006_gene2184	1.238e-36	145.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,47NH9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2721149_7	1125863.JAFN01000001_gene1816	8.526e-06	59.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
YHH2_k127_2742538_4	452637.Oter_3754	1.44e-07	57.0	2CGCF@1|root,33ZA6@2|Bacteria,46YV0@74201|Verrucomicrobia,3K85C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2742538_2	497964.CfE428DRAFT_6520	1.953e-42	165.0	COG0811@1|root,COG0811@2|Bacteria,46T1R@74201|Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH2_k127_2742538_3	497964.CfE428DRAFT_6519	3.545e-17	86.0	COG0848@1|root,COG0848@2|Bacteria,46T7H@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH2_k127_2742538_1	497964.CfE428DRAFT_5395	1.205e-159	509.0	COG0136@1|root,COG0136@2|Bacteria,46S74@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YHH2_k127_2742538_0	402777.KB235903_gene1074	4.114e-298	930.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1H6Y0@1150|Oscillatoriales	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
YHH2_k127_2751120_2	1304878.AUGD01000003_gene2762	6.796e-11	73.0	COG1409@1|root,COG1409@2|Bacteria,1MVDW@1224|Proteobacteria,2TQNM@28211|Alphaproteobacteria,3JS85@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH2_k127_2751120_3	405948.SACE_2104	2.965e-06	57.0	COG5640@1|root,COG5640@2|Bacteria,2IBU4@201174|Actinobacteria,4E0W4@85010|Pseudonocardiales	201174|Actinobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
YHH2_k127_2751120_1	497964.CfE428DRAFT_1374	1.411e-11	69.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
YHH2_k127_2807278_5	243159.AFE_0594	1.062e-37	150.0	COG3963@1|root,COG3963@2|Bacteria,1N1KB@1224|Proteobacteria,1S9ZD@1236|Gammaproteobacteria,2NCP5@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH2_k127_2807278_2	497964.CfE428DRAFT_2911	1.81e-116	387.0	COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
YHH2_k127_2807278_4	240016.ABIZ01000001_gene4281	8.015e-43	169.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia,2IUNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glyco_transf_9,Lip_A_acyltrans
YHH2_k127_2807278_3	886293.Sinac_5304	2.064e-116	390.0	COG0477@1|root,COG2814@2|Bacteria,2IY3A@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
YHH2_k127_2807278_1	497964.CfE428DRAFT_4013	2.116e-156	503.0	COG0513@1|root,COG0513@2|Bacteria,46TUA@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
YHH2_k127_2807278_0	240016.ABIZ01000001_gene3608	0.0	1113.0	COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia,2ITTI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
YHH2_k127_2807775_2	756272.Plabr_2714	1.488e-93	314.0	COG2755@1|root,COG2755@2|Bacteria,2J37I@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH2_k127_2807775_3	452637.Oter_2095	1.655e-85	292.0	COG0526@1|root,COG0526@2|Bacteria,46TGF@74201|Verrucomicrobia	74201|Verrucomicrobia	CO	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH2_k127_2807775_1	382464.ABSI01000011_gene2675	1.626e-100	350.0	COG2610@1|root,COG2610@2|Bacteria,46UQS@74201|Verrucomicrobia,2IVYC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	GntP family permease	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
YHH2_k127_2807775_0	340099.Teth39_0981	8.461e-159	527.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,42EXS@68295|Thermoanaerobacterales	186801|Clostridia	E	M3B, thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YHH2_k127_2807775_5	261292.Nit79A3_0969	1.776e-09	65.0	2DSEK@1|root,33FUB@2|Bacteria,1NI40@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082,VPEP
YHH2_k127_2807775_4	314285.KT71_04495	1.654e-09	68.0	2DSEK@1|root,33FUB@2|Bacteria,1NI40@1224|Proteobacteria,1SJE3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082,VPEP
YHH2_k127_2807900_2	452637.Oter_1999	1.736e-09	71.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
YHH2_k127_2807900_1	1396141.BATP01000028_gene2285	2.736e-90	325.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
YHH2_k127_2807900_0	861299.J421_1753	2.81e-144	482.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
YHH2_k127_2816393_2	1123054.KB907706_gene2296	1.725e-32	145.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,Gram_pos_anchor,Laminin_G_3
YHH2_k127_2816393_0	1232410.KI421416_gene2655	9.75e-52	193.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria,43U05@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2816393_1	1379698.RBG1_1C00001G0297	4.71e-46	172.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
YHH2_k127_2824475_5	397948.Cmaq_1622	1.6e-36	154.0	COG1593@1|root,arCOG08625@2157|Archaea	2157|Archaea	G	Glucuronate isomerase	-	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
YHH2_k127_2824475_8	768710.DesyoDRAFT_1951	3.264e-07	63.0	2CJTW@1|root,33NBH@2|Bacteria,1VM99@1239|Firmicutes,24UVS@186801|Clostridia,26684@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2824475_2	1089553.Tph_c09100	1.264e-107	367.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,42G9W@68295|Thermoanaerobacterales	186801|Clostridia	H	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
YHH2_k127_2824475_0	344747.PM8797T_26205	3.211e-236	783.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	DUF1863,PQQ,PQQ_2,PQQ_3
YHH2_k127_2824475_4	449447.MAE_43100	8.895e-53	216.0	COG1262@1|root,COG4248@1|root,COG1262@2|Bacteria,COG4248@2|Bacteria,1G1D0@1117|Cyanobacteria	1117|Cyanobacteria	S	protein with protein kinase and helix-hairpin-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
YHH2_k127_2824475_3	452637.Oter_0312	3.969e-78	300.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
YHH2_k127_2824475_6	1116472.MGMO_17c00160	5.316e-19	104.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1RC5K@1224|Proteobacteria,1S3I9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH2_k127_2824475_1	1291050.JAGE01000001_gene867	3.172e-175	578.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH2_k127_2824475_7	1089548.KI783301_gene1955	1.39e-15	89.0	COG5464@1|root,COG5464@2|Bacteria,1UGME@1239|Firmicutes,4HEK5@91061|Bacilli	91061|Bacilli	S	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
YHH2_k127_2825349_2	497964.CfE428DRAFT_3287	7.529e-07	52.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_2825349_1	497964.CfE428DRAFT_3286	1.985e-20	107.0	COG1928@1|root,COG1928@2|Bacteria,46UW1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2825349_3	1396141.BATP01000039_gene1306	8.26e-05	55.0	2BUZ4@1|root,32QBJ@2|Bacteria,46WND@74201|Verrucomicrobia,2IUIR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
YHH2_k127_2825349_0	1396141.BATP01000039_gene1307	1.009e-120	414.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46SBB@74201|Verrucomicrobia,2ITWV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
YHH2_k127_2833707_2	1156937.MFUM_1020111	3.261e-111	374.0	COG1236@1|root,COG1236@2|Bacteria,46SQ0@74201|Verrucomicrobia,37FVJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,Lactamase_B,RMMBL
YHH2_k127_2833707_0	575540.Isop_1510	3.238e-224	701.0	COG2115@1|root,COG2115@2|Bacteria,2IWUS@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH2_k127_2833707_1	401526.TcarDRAFT_1824	4.042e-129	457.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H2CW@909932|Negativicutes	909932|Negativicutes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YHH2_k127_2857291_1	497964.CfE428DRAFT_4416	5.259e-181	583.0	COG3119@1|root,COG3119@2|Bacteria,46U45@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH2_k127_2857291_0	794903.OPIT5_06915	1.861e-210	666.0	COG1488@1|root,COG1488@2|Bacteria,46SAG@74201|Verrucomicrobia,3K911@414999|Opitutae	414999|Opitutae	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
YHH2_k127_2857291_3	1396141.BATP01000030_gene3653	1.42e-86	290.0	COG1335@1|root,COG1335@2|Bacteria,46UUK@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	isochorismatase hydrolase	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
YHH2_k127_2857291_4	743722.Sph21_2661	5.858e-31	131.0	COG4122@1|root,COG4122@2|Bacteria,4PBU0@976|Bacteroidetes,1IZHJ@117747|Sphingobacteriia	976|Bacteroidetes	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
YHH2_k127_2857291_2	1124780.ANNU01000071_gene1021	2.014e-165	533.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1,Sugar_tr
YHH2_k127_2857291_5	1125701.HMPREF1221_01616	1.056e-13	84.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2858709_0	378806.STAUR_6990	1.409e-32	149.0	COG4412@1|root,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M36,REJ
YHH2_k127_2858709_1	314285.KT71_18736	2.565e-16	95.0	COG1404@1|root,COG1520@1|root,COG3209@1|root,COG3291@1|root,COG3391@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	rhs family	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YHH2_k127_2858709_2	102129.Lepto7375DRAFT_8139	1.617e-12	70.0	28IHG@1|root,2Z8IP@2|Bacteria,1G4GY@1117|Cyanobacteria,1H8KJ@1150|Oscillatoriales	1117|Cyanobacteria	S	SPTR Alr4702 protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
YHH2_k127_2859960_2	497964.CfE428DRAFT_6409	6.096e-103	358.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YHH2_k127_2859960_4	1123312.KB904579_gene544	6.295e-39	149.0	COG1388@1|root,COG3209@1|root,COG3210@1|root,COG1388@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli	91061|Bacilli	M	COG3209 Rhs family protein	wapA	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0004549,GO:0006139,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016078,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YHH2_k127_2859960_6	345219.Bcoa_1697	2.161e-25	111.0	28NWS@1|root,2ZBUK@2|Bacteria,1V2K3@1239|Firmicutes,4HGVV@91061|Bacilli,1ZH7X@1386|Bacillus	91061|Bacilli	S	SMI1-KNR4 cell-wall	-	-	-	-	-	-	-	-	-	-	-	-	SUKH_5
YHH2_k127_2859960_5	1449063.JMLS01000037_gene1759	1.307e-38	153.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
YHH2_k127_2859960_1	1163617.SCD_n02853	1.042e-165	528.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
YHH2_k127_2859960_0	497964.CfE428DRAFT_0060	2.727e-316	1038.0	COG2373@1|root,COG2373@2|Bacteria,46U44@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Alpha-2-Macroglobulin	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,Thiol-ester_cl
YHH2_k127_2859960_3	497964.CfE428DRAFT_0059	9.549e-67	262.0	COG2373@1|root,COG2373@2|Bacteria,46U44@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Alpha-2-Macroglobulin	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
YHH2_k127_2882483_1	335543.Sfum_0674	8.54e-113	372.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,42TQ5@68525|delta/epsilon subdivisions,2WQ0T@28221|Deltaproteobacteria,2MRV7@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH2_k127_2882483_0	886293.Sinac_6489	6.971e-149	497.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
YHH2_k127_2882483_2	497964.CfE428DRAFT_4864	2.849e-55	202.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2883366_1	497964.CfE428DRAFT_3531	2.321e-94	316.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
YHH2_k127_2883366_2	349124.Hhal_2077	7.531e-51	183.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1WYFF@135613|Chromatiales	135613|Chromatiales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YHH2_k127_2883366_3	289376.THEYE_A1581	1.026e-41	158.0	COG0103@1|root,COG0103@2|Bacteria,3J0N4@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
YHH2_k127_2883366_0	497964.CfE428DRAFT_2151	2.212e-128	419.0	COG0002@1|root,COG0002@2|Bacteria,46SA3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YHH2_k127_2883366_4	197221.22295637	5.181e-19	95.0	COG1364@1|root,COG1364@2|Bacteria,1G1H7@1117|Cyanobacteria	1117|Cyanobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.argJ	ArgJ
YHH2_k127_2886426_0	498211.CJA_3332	8.512e-24	113.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1FFYW@10|Cellvibrio	1236|Gammaproteobacteria	NU	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
YHH2_k127_2886426_2	713586.KB900536_gene1831	0.0003019	53.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1WXGR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
YHH2_k127_2886426_1	521674.Plim_3639	1.909e-05	53.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
YHH2_k127_2898449_3	1123508.JH636439_gene737	9.931e-68	242.0	COG1409@1|root,COG1409@2|Bacteria	1123508.JH636439_gene737|-	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2898449_1	314230.DSM3645_29267	1.604e-171	550.0	COG0006@1|root,COG0006@2|Bacteria,2J3P5@203682|Planctomycetes	203682|Planctomycetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
YHH2_k127_2898449_0	1278073.MYSTI_00528	1.623e-178	574.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2YWP2@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
YHH2_k127_2898449_2	452637.Oter_3627	2.225e-165	534.0	COG1055@1|root,COG1055@2|Bacteria,46S61@74201|Verrucomicrobia,3K7MJ@414999|Opitutae	414999|Opitutae	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
YHH2_k127_2921137_2	338969.Rfer_0253	9.215e-75	255.0	COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria	1224|Proteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YHH2_k127_2921137_3	338969.Rfer_0254	3.801e-51	196.0	COG0457@1|root,COG0457@2|Bacteria,1NYJF@1224|Proteobacteria	1224|Proteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2921137_1	452637.Oter_1494	2.549e-113	381.0	COG0534@1|root,COG0534@2|Bacteria,46UTM@74201|Verrucomicrobia,3K890@414999|Opitutae	414999|Opitutae	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
YHH2_k127_2921137_0	1408473.JHXO01000007_gene958	2.121e-152	488.0	COG2502@1|root,COG2502@2|Bacteria,4NFZA@976|Bacteroidetes,2FMP0@200643|Bacteroidia	976|Bacteroidetes	E	aspartate--ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
YHH2_k127_2921137_4	864069.MicloDRAFT_00033440	4.791e-26	126.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,1JU30@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdh	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N,Response_reg
YHH2_k127_2982109_0	1227739.Hsw_PA0012	1.34e-188	612.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
YHH2_k127_2982109_2	1121405.dsmv_1316	3.762e-84	300.0	2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,42NQC@68525|delta/epsilon subdivisions,2WMFH@28221|Deltaproteobacteria,2MIVU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868
YHH2_k127_2982109_1	933262.AXAM01000085_gene1058	7.929e-93	313.0	COG1159@1|root,COG1159@2|Bacteria,1QW17@1224|Proteobacteria,42MZH@68525|delta/epsilon subdivisions,2WKAE@28221|Deltaproteobacteria,2MHS2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
YHH2_k127_2992856_4	1385935.N836_13145	5.161e-21	112.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_2992856_3	1121920.AUAU01000009_gene1881	5.012e-51	211.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
YHH2_k127_2992856_7	1336803.PHEL49_1867	1.002e-06	64.0	COG2312@1|root,COG3537@1|root,COG4935@1|root,COG5337@1|root,COG2312@2|Bacteria,COG3537@2|Bacteria,COG4935@2|Bacteria,COG5337@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,3VX3A@52959|Polaribacter	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
YHH2_k127_2992856_8	1157635.KB892020_gene158	8.052e-05	58.0	COG3204@1|root,COG3204@2|Bacteria,2I94U@201174|Actinobacteria	201174|Actinobacteria	K	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Phytase-like
YHH2_k127_2992856_0	1396141.BATP01000034_gene4198	0.0	1369.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_2992856_5	1229276.DI53_3943	8.886e-09	71.0	COG3866@1|root,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
YHH2_k127_2992856_1	1396141.BATP01000034_gene4198	3.141e-262	901.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_2992856_6	55601.VANGNB10_cI0958	2.023e-08	70.0	COG3469@1|root,COG3979@1|root,COG3469@2|Bacteria,COG3979@2|Bacteria,1MUUS@1224|Proteobacteria,1RYTJ@1236|Gammaproteobacteria,1XUGW@135623|Vibrionales	135623|Vibrionales	G	Glycosyl hydrolases family 18	chiA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
YHH2_k127_2992856_2	1121897.AUGO01000002_gene2177	3.192e-86	328.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia,2NYF6@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
YHH2_k127_3017471_0	497964.CfE428DRAFT_3359	5.954e-246	770.0	COG0539@1|root,COG0539@2|Bacteria,46SFY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
YHH2_k127_3017471_1	452637.Oter_2683	9.481e-32	126.0	COG0162@1|root,COG0162@2|Bacteria,46UVG@74201|Verrucomicrobia,3K7IA@414999|Opitutae	414999|Opitutae	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
YHH2_k127_3065652_2	1041139.KB902746_gene3228	1.022e-114	387.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2TRQB@28211|Alphaproteobacteria,4BP1C@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
YHH2_k127_3065652_4	1396141.BATP01000030_gene3631	6.997e-77	283.0	COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae	2|Bacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
YHH2_k127_3065652_6	794903.OPIT5_01675	3.031e-28	122.0	2DE2A@1|root,2ZK73@2|Bacteria,46Y2T@74201|Verrucomicrobia,3K8UK@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
YHH2_k127_3065652_0	107635.AZUO01000001_gene1933	4.122e-151	490.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,2TUDK@28211|Alphaproteobacteria,36ZA6@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Aminotransferase class-III	MA20_16020	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
YHH2_k127_3065652_1	243233.MCA2756	2.718e-130	429.0	COG0438@1|root,COG0438@2|Bacteria,1NMB5@1224|Proteobacteria,1RRVU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Sulfotransfer_3
YHH2_k127_3065652_7	1382306.JNIM01000001_gene2708	1.534e-18	95.0	COG0586@1|root,COG0586@2|Bacteria,2G79V@200795|Chloroflexi	200795|Chloroflexi	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
YHH2_k127_3065652_5	765420.OSCT_1937	1.224e-47	176.0	COG0745@1|root,COG0745@2|Bacteria,2G9Q2@200795|Chloroflexi,377GJ@32061|Chloroflexia	32061|Chloroflexia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH2_k127_3065652_3	1173028.ANKO01000141_gene601	2.661e-84	306.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1G13T@1117|Cyanobacteria,1H77Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
YHH2_k127_309322_1	497964.CfE428DRAFT_2602	6.711e-34	132.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
YHH2_k127_309322_2	382464.ABSI01000010_gene3771	3.77e-23	106.0	2FBS3@1|root,343WW@2|Bacteria,46X6J@74201|Verrucomicrobia,2IUQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_309322_5	452637.Oter_0649	0.0005328	49.0	299RH@1|root,2ZWTR@2|Bacteria,46WTD@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_309322_3	497964.CfE428DRAFT_1031	5.335e-16	91.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_309322_0	1230476.C207_05596	4.322e-198	636.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,3JUXS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Domain of unknown function (DUF4070)	MA20_16100	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
YHH2_k127_3107505_4	1283283.ATXA01000013_gene3483	3.133e-14	85.0	COG0737@1|root,COG3204@1|root,COG3401@1|root,COG3540@1|root,COG0737@2|Bacteria,COG3204@2|Bacteria,COG3401@2|Bacteria,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	3.1.3.1,3.1.3.6,3.1.4.16	ko:K01113,ko:K01119	ko00230,ko00240,ko00790,ko01100,ko02020,map00230,map00240,map00790,map01100,map02020	M00126	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R04620,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Big_4,F5_F8_type_C,LTD,Laminin_G_3,Metallophos,PhoD,SLH,SdiA-regulated
YHH2_k127_3107505_2	497964.CfE428DRAFT_4864	4.11e-61	222.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3107505_1	398767.Glov_0596	2.516e-68	249.0	COG1785@1|root,COG4222@1|root,COG1785@2|Bacteria,COG4222@2|Bacteria,1MXI2@1224|Proteobacteria,42N40@68525|delta/epsilon subdivisions,2WKUV@28221|Deltaproteobacteria,43V5N@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Alkaline phosphatase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
YHH2_k127_3107505_3	382464.ABSI01000005_gene1162	4.969e-32	131.0	2E0ZB@1|root,32WFN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3107505_0	1047013.AQSP01000132_gene1749	8.477e-73	257.0	COG0123@1|root,COG0123@2|Bacteria,2NPPE@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
YHH2_k127_3107505_5	1120999.JONM01000017_gene77	5.342e-07	57.0	28NY3@1|root,2ZBVC@2|Bacteria,1RCZB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3127566_1	1392490.JHZX01000001_gene201	7.906e-50	201.0	COG1572@1|root,COG2931@1|root,COG3211@1|root,COG3540@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3211@2|Bacteria,COG3540@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia	976|Bacteroidetes	Q	twin-arginine translocation pathway signal protein	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
YHH2_k127_3127566_2	999419.HMPREF1077_03046	7.819e-40	156.0	COG2303@1|root,COG2303@2|Bacteria,4PKTW@976|Bacteroidetes,2FS8M@200643|Bacteroidia,22XM0@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_3127566_0	1168034.FH5T_18125	3.973e-81	289.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_3150698_3	1396418.BATQ01000087_gene1046	1.057e-56	207.0	COG0438@1|root,COG0438@2|Bacteria,46UG2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH2_k127_3150698_6	1396418.BATQ01000106_gene5334	3.909e-38	149.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia,2IUVD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
YHH2_k127_3150698_7	1396141.BATP01000026_gene1042	7.697e-09	63.0	2F8IJ@1|root,340XC@2|Bacteria,46WTZ@74201|Verrucomicrobia,2IUYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3150698_4	497964.CfE428DRAFT_4946	1.958e-53	194.0	2EK8J@1|root,33DYX@2|Bacteria,46VTQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3150698_0	1210884.HG799464_gene11020	5.783e-134	439.0	COG1541@1|root,COG1541@2|Bacteria,2IXI4@203682|Planctomycetes	203682|Planctomycetes	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
YHH2_k127_3150698_1	497964.CfE428DRAFT_4760	9.284e-123	401.0	COG1082@1|root,COG1082@2|Bacteria,46SWE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_3150698_2	1185876.BN8_01398	4.838e-88	305.0	COG1413@1|root,COG1413@2|Bacteria,4NK5S@976|Bacteroidetes,47N32@768503|Cytophagia	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_3150698_5	700598.Niako_1916	1.088e-51	203.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,1IPWK@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycoside hydrolase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
YHH2_k127_3167005_4	331678.Cphamn1_0650	9.716e-28	121.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YHH2_k127_3167005_0	653733.Selin_0567	1.572e-129	437.0	COG0348@1|root,COG1622@1|root,COG0348@2|Bacteria,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	vnfA	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,Fer4_5,Sigma54_activat,cNMP_binding
YHH2_k127_3167005_7	1380391.JIAS01000012_gene4158	1.78e-14	84.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MVYW@1224|Proteobacteria,2TS8D@28211|Alphaproteobacteria,2JVKC@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C,Cytochrome_CBB3
YHH2_k127_3167005_6	159087.Daro_1843	4.185e-15	79.0	2E5GP@1|root,3308B@2|Bacteria,1N858@1224|Proteobacteria,2VW3P@28216|Betaproteobacteria,2KXA9@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3167005_2	1255043.TVNIR_0494	6.955e-109	367.0	COG0577@1|root,COG0577@2|Bacteria,1P00G@1224|Proteobacteria,1T3UT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
YHH2_k127_3167005_5	338966.Ppro_3642	5.789e-21	99.0	COG4393@1|root,COG4393@2|Bacteria,1R507@1224|Proteobacteria,42NQA@68525|delta/epsilon subdivisions,2WQ0C@28221|Deltaproteobacteria,43UZR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318
YHH2_k127_3167005_3	1123508.JH636441_gene2994	2.896e-38	155.0	COG1595@1|root,COG1595@2|Bacteria,2IZAB@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YHH2_k127_3167005_1	452637.Oter_1389	1.287e-127	424.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YHH2_k127_3182294_0	497964.CfE428DRAFT_2824	2.191e-310	991.0	2DBSP@1|root,2ZAT9@2|Bacteria,46TYZ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3182294_1	497964.CfE428DRAFT_2825	5.368e-175	559.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,46TEF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Von Willebrand factor	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,VWA_3,vWF_A
YHH2_k127_3204018_6	1121091.AUMP01000003_gene2769	7.349e-32	131.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli	91061|Bacilli	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
YHH2_k127_3204018_4	429009.Adeg_1150	1.194e-52	196.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,42GDJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
YHH2_k127_3204018_2	1396141.BATP01000022_gene350	2.22e-75	262.0	COG2138@1|root,COG2138@2|Bacteria,46SPE@74201|Verrucomicrobia,2IV6F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	CbiX	-	-	-	-	-	-	-	-	-	-	-	-	CbiX
YHH2_k127_3204018_0	489825.LYNGBM3L_36680	1.908e-174	555.0	COG0579@1|root,COG0579@2|Bacteria,1G0XV@1117|Cyanobacteria,1H77Y@1150|Oscillatoriales	1117|Cyanobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
YHH2_k127_3204018_1	382464.ABSI01000011_gene3187	1.034e-111	383.0	COG0815@1|root,COG0815@2|Bacteria,46W4F@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the fatty acyl group on membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3204018_3	670487.Ocepr_1534	5.574e-58	218.0	COG3971@1|root,COG3971@2|Bacteria,1WIN3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	2-oxopent-4-enoate hydratase activity	-	-	4.2.1.80	ko:K02509,ko:K02554	ko00350,ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00350,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R02601,R04132,R04781,R06897	RC00750,RC01213,RC01615,RC02595	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
YHH2_k127_3204018_7	251229.Chro_2352	1.655e-18	96.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721,ko:K07011,ko:K20444	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
YHH2_k127_3204018_5	1121091.AUMP01000011_gene1779	2.042e-35	147.0	COG0438@1|root,COG0438@2|Bacteria,1V4TS@1239|Firmicutes,4HC19@91061|Bacilli	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
YHH2_k127_3239004_19	1239962.C943_03621	8.695e-08	57.0	COG3258@1|root,COG3258@2|Bacteria,4PMKG@976|Bacteroidetes,47R15@768503|Cytophagia	976|Bacteroidetes	C	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
YHH2_k127_3239004_2	1123070.KB899254_gene1284	1.488e-119	398.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
YHH2_k127_3239004_8	378806.STAUR_7893	1.38e-64	229.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,42RT9@68525|delta/epsilon subdivisions,2WNJ0@28221|Deltaproteobacteria,2YWKZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
YHH2_k127_3239004_15	452637.Oter_1500	2.254e-30	124.0	COG3824@1|root,COG3824@2|Bacteria,46WK7@74201|Verrucomicrobia,3K8CH@414999|Opitutae	414999|Opitutae	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
YHH2_k127_3239004_3	497964.CfE428DRAFT_4021	3.137e-107	360.0	COG1600@1|root,COG1600@2|Bacteria,46SDV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
YHH2_k127_3239004_17	439235.Dalk_3087	6.958e-20	97.0	COG1763@1|root,COG1763@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	ko:K03753,ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	-
YHH2_k127_3239004_16	497964.CfE428DRAFT_3013	8.332e-29	121.0	2E6X2@1|root,331GI@2|Bacteria,46T38@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3239004_5	439235.Dalk_3089	8.021e-101	352.0	2A102@1|root,30P5F@2|Bacteria,1NQ9E@1224|Proteobacteria,433GU@68525|delta/epsilon subdivisions,2WXXA@28221|Deltaproteobacteria	1224|Proteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
YHH2_k127_3239004_1	222984.JNCS01000005_gene1526	1.347e-139	458.0	COG1012@1|root,arCOG01252@2157|Archaea,2XT1Y@28890|Euryarchaeota,23SU2@183963|Halobacteria	183963|Halobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	aldY3	-	1.2.1.26	ko:K19588	ko00040,ko00053,map00040,map00053	-	R00264	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
YHH2_k127_3239004_6	314230.DSM3645_13565	1.256e-77	269.0	COG3970@1|root,COG3970@2|Bacteria,2IWUC@203682|Planctomycetes	203682|Planctomycetes	S	fumarylacetoacetate (FAA) hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
YHH2_k127_3239004_10	1266914.ATUK01000010_gene1326	1.616e-53	197.0	COG1943@1|root,COG1943@2|Bacteria,1RBFM@1224|Proteobacteria,1SPM8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH2_k127_3239004_21	344747.PM8797T_31343	1.333e-06	49.0	2E3RU@1|root,32YPG@2|Bacteria,2J4CJ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3239004_22	323848.Nmul_A2012	7.062e-05	45.0	COG4974@1|root,COG4974@2|Bacteria,1R43B@1224|Proteobacteria,2VNAM@28216|Betaproteobacteria,373JF@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
YHH2_k127_3239004_20	33905.BTHE_1901	1.238e-06	60.0	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,2I42H@201174|Actinobacteria	201174|Actinobacteria	M	Protein of unknown function (DUF3289)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3289
YHH2_k127_3239004_18	278957.ABEA03000019_gene1870	3.136e-15	88.0	COG2165@1|root,COG2165@2|Bacteria,46Y07@74201|Verrucomicrobia,3K8QE@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
YHH2_k127_3239004_14	1247726.MIM_c25300	3.631e-32	135.0	COG2010@1|root,COG2010@2|Bacteria,1RKH6@1224|Proteobacteria,2VQE8@28216|Betaproteobacteria,3T3ZE@506|Alcaligenaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	cccA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
YHH2_k127_3239004_12	583355.Caka_0026	9.302e-48	183.0	COG2993@1|root,COG2993@2|Bacteria,46T1F@74201|Verrucomicrobia,3K82J@414999|Opitutae	414999|Opitutae	C	cytochrome c oxidase	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
YHH2_k127_3239004_4	794903.OPIT5_22615	3.519e-104	356.0	COG3278@1|root,COG3278@2|Bacteria,46T64@74201|Verrucomicrobia,3K7FT@414999|Opitutae	414999|Opitutae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
YHH2_k127_3239004_23	452637.Oter_3929	0.0004719	48.0	2B8Q9@1|root,321ZW@2|Bacteria,46XX6@74201|Verrucomicrobia,3K8IF@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3239004_7	382464.ABSI01000020_gene188	7.293e-75	266.0	COG4531@1|root,COG4531@2|Bacteria,46SME@74201|Verrucomicrobia,2ITX9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3239004_11	497964.CfE428DRAFT_2221	6.022e-51	188.0	COG2010@1|root,COG2010@2|Bacteria,46SV4@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YHH2_k127_3239004_9	794903.OPIT5_22590	6.302e-58	213.0	COG2010@1|root,COG2010@2|Bacteria,46V1P@74201|Verrucomicrobia,3K7WS@414999|Opitutae	414999|Opitutae	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YHH2_k127_3239004_0	278957.ABEA03000189_gene958	6.762e-212	671.0	COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,3K751@414999|Opitutae	414999|Opitutae	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
YHH2_k127_3239004_13	382464.ABSI01000020_gene184	4.699e-45	167.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,2ITQX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
YHH2_k127_3256959_0	452637.Oter_3559	1.008e-169	543.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,3K7BT@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
YHH2_k127_3256959_1	497964.CfE428DRAFT_1577	2.629e-151	488.0	COG0502@1|root,COG0502@2|Bacteria,46SFX@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
YHH2_k127_3256959_3	1260251.SPISAL_00975	4.958e-07	55.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149,ko:K03154	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiS
YHH2_k127_3256959_2	247490.KSU1_C1712	8.443e-50	184.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3272077_0	530564.Psta_0624	1.517e-145	473.0	COG0673@1|root,COG0673@2|Bacteria,2IYHK@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_3272077_3	1123070.KB899248_gene195	2.905e-07	63.0	COG0515@1|root,COG0515@2|Bacteria,46WZX@74201|Verrucomicrobia,2IW4Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3272077_2	497964.CfE428DRAFT_0845	1.68e-117	385.0	COG0078@1|root,COG0078@2|Bacteria,46SA5@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YHH2_k127_3272077_1	1403819.BATR01000175_gene5929	1.657e-135	438.0	COG1995@1|root,COG1995@2|Bacteria,46TI8@74201|Verrucomicrobia,2IWMA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Pyridoxal phosphate biosynthetic protein PdxA	-	-	-	-	-	-	-	-	-	-	-	-	PdxA
YHH2_k127_3305654_1	1396418.BATQ01000135_gene3639	8.498e-88	297.0	COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia,2ITJI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
YHH2_k127_3305654_6	794903.OPIT5_30840	5.211e-21	95.0	COG0836@1|root,COG0836@2|Bacteria,46UR9@74201|Verrucomicrobia,3K7G3@414999|Opitutae	414999|Opitutae	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
YHH2_k127_3305654_2	278957.ABEA03000200_gene4374	2.886e-61	221.0	COG0836@1|root,COG0836@2|Bacteria,46UR9@74201|Verrucomicrobia,3K7G3@414999|Opitutae	414999|Opitutae	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
YHH2_k127_3305654_3	211165.AJLN01000075_gene6274	6.934e-43	161.0	COG0454@1|root,COG0454@2|Bacteria,1GQZV@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH2_k127_3305654_4	340177.Cag_0707	3.872e-32	128.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_3305654_7	555779.Dthio_PD1485	3.859e-15	79.0	2EQIX@1|root,33I4Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
YHH2_k127_3305654_8	497964.CfE428DRAFT_4678	9.426e-10	74.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,CarboxypepD_reg,He_PIG,LysM,PSII_BNR,SLH,TIG,fn3
YHH2_k127_3305654_0	1396141.BATP01000034_gene4198	8.706e-241	820.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_3305654_5	278957.ABEA03000176_gene2840	1.36e-22	104.0	COG4309@1|root,COG4309@2|Bacteria,46XTU@74201|Verrucomicrobia,3K814@414999|Opitutae	414999|Opitutae	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
YHH2_k127_3346214_0	1499967.BAYZ01000185_gene4530	1.573e-135	471.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
YHH2_k127_3346214_1	1396141.BATP01000034_gene4198	1.189e-12	81.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_3359294_2	595460.RRSWK_05060	5.376e-43	160.0	COG1520@1|root,COG1520@2|Bacteria,2IYEA@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YHH2_k127_3359294_1	243231.GSU0700	6.061e-85	301.0	COG0784@1|root,COG2202@1|root,COG2208@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria,1NC9X@1224|Proteobacteria,43C4D@68525|delta/epsilon subdivisions,2X7EU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domains REC, PAS, PAS, PP2C	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_3,PAS_9,Response_reg,SpoIIE
YHH2_k127_3359294_3	1242864.D187_006518	4.147e-24	119.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2X8PP@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
YHH2_k127_3359294_0	478741.JAFS01000001_gene2217	8.378e-126	412.0	COG0507@1|root,COG0507@2|Bacteria,46USC@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Helix-hairpin-helix containing domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
YHH2_k127_3426623_2	1396141.BATP01000023_gene554	3.273e-99	346.0	COG2340@1|root,COG2340@2|Bacteria,46VC3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
YHH2_k127_3426623_3	240016.ABIZ01000001_gene2350	1.643e-29	120.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,2IUHZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH2_k127_3426623_1	452637.Oter_2237	1.438e-102	344.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH2_k127_3426623_4	452637.Oter_2236	4.667e-12	70.0	COG4877@1|root,COG4877@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
YHH2_k127_3428490_3	28229.ND2E_0431	1.713e-11	79.0	COG2340@1|root,COG2931@1|root,COG3227@1|root,COG4932@1|root,COG5644@1|root,COG2340@2|Bacteria,COG2931@2|Bacteria,COG3227@2|Bacteria,COG4932@2|Bacteria,COG5644@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,2Q7GE@267889|Colwelliaceae	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K11005	-	-	-	-	ko00000,ko02000,ko02042	1.C.11	-	-	Big_3_2,Cadherin_3,Calx-beta,He_PIG,HemolysinCabind,OmpA_membrane,RTX,RTX_C,VWA_2,fn3
YHH2_k127_3428490_1	1121920.AUAU01000009_gene1881	4.623e-21	110.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
YHH2_k127_3428490_2	1449063.JMLS01000001_gene4394	8.292e-13	83.0	COG3506@1|root,COG3866@1|root,COG4733@1|root,COG3506@2|Bacteria,COG3866@2|Bacteria,COG4733@2|Bacteria,1UNKR@1239|Firmicutes,4HTXI@91061|Bacilli,277M7@186822|Paenibacillaceae	91061|Bacilli	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3428490_0	1267535.KB906767_gene808	5.285e-58	209.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_3430242_3	497964.CfE428DRAFT_3635	1.997e-132	445.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
YHH2_k127_3430242_4	55529.EKX47288	1.205e-102	348.0	COG0144@1|root,KOG1122@2759|Eukaryota	2759|Eukaryota	J	rRNA (cytosine-C5-)-methyltransferase activity	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
YHH2_k127_3430242_2	1185876.BN8_02314	4.832e-134	437.0	COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,47N9K@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_3430242_0	1303518.CCALI_01847	5.145e-203	651.0	COG0441@1|root,COG0441@2|Bacteria	2|Bacteria	J	threonyl-tRNA aminoacylation	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
YHH2_k127_3430242_1	497964.CfE428DRAFT_2061	2.719e-200	638.0	COG0138@1|root,COG0138@2|Bacteria,46S5H@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
YHH2_k127_3430242_6	1123242.JH636435_gene1439	0.0005322	49.0	COG1520@1|root,COG1716@1|root,COG1520@2|Bacteria,COG1716@2|Bacteria,2IXDN@203682|Planctomycetes	203682|Planctomycetes	T	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,PQQ_2
YHH2_k127_3430242_5	743720.Psefu_1696	4.665e-14	79.0	COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1SC60@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1596 Periplasmic protein involved in polysaccharide export	gumB	-	-	ko:K20988	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YHH2_k127_3432193_3	1370125.AUWT01000017_gene2448	1.937e-23	109.0	COG2730@1|root,COG3469@1|root,COG2730@2|Bacteria,COG3469@2|Bacteria,2GJTU@201174|Actinobacteria,2384A@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 18 family	chiA2	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	CBM_2,CBM_4_9,Glyco_hydro_18,Ricin_B_lectin,fn3
YHH2_k127_3432193_2	1429046.RR21198_3505	3.444e-25	115.0	COG5036@1|root,COG5036@2|Bacteria,2GKBU@201174|Actinobacteria,4FYJY@85025|Nocardiaceae	201174|Actinobacteria	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
YHH2_k127_3432193_0	316067.Geob_3573	2.274e-77	286.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42RAK@68525|delta/epsilon subdivisions,2WJRA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9
YHH2_k127_3432193_1	1123242.JH636435_gene1640	1.778e-72	252.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
YHH2_k127_3520771_0	497964.CfE428DRAFT_1931	3.364e-92	314.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH2_k127_3520771_1	1123508.JH636448_gene7647	2.016e-77	263.0	COG1225@1|root,COG1225@2|Bacteria,2IYHT@203682|Planctomycetes	203682|Planctomycetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH2_k127_3520771_2	478741.JAFS01000002_gene127	6.082e-39	149.0	COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia,37G6E@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YHH2_k127_3522423_1	926550.CLDAP_09900	4.737e-22	113.0	COG3391@1|root,COG3391@2|Bacteria,2G9E4@200795|Chloroflexi	200795|Chloroflexi	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3522423_0	102232.GLO73106DRAFT_00005410	7.459e-45	188.0	COG2931@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,1G67W@1117|Cyanobacteria	1117|Cyanobacteria	Q	polymorphic outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,HemolysinCabind
YHH2_k127_3528971_1	1123008.KB905693_gene1177	3.328e-107	357.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes	976|Bacteroidetes	G	PFAM YdjC family protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
YHH2_k127_3528971_2	452637.Oter_1366	7.631e-92	329.0	COG3507@1|root,COG3940@1|root,COG3507@2|Bacteria,COG3940@2|Bacteria	2|Bacteria	G	arabinan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,Glyco_hydro_43
YHH2_k127_3528971_0	1396141.BATP01000022_gene379	1.926e-141	476.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,Big_4,Glyco_hydro_43,RicinB_lectin_2
YHH2_k127_3528971_4	452637.Oter_0312	4.296e-18	100.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
YHH2_k127_3528971_3	313606.M23134_00255	9.944e-74	277.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,47RAA@768503|Cytophagia	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
YHH2_k127_3531158_6	452637.Oter_3491	1.14e-28	130.0	COG2911@1|root,COG2911@2|Bacteria,46UPJ@74201|Verrucomicrobia,3K7BC@414999|Opitutae	414999|Opitutae	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
YHH2_k127_3531158_7	1297742.A176_02717	2.965e-28	116.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2YVNG@29|Myxococcales	28221|Deltaproteobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
YHH2_k127_3531158_1	314230.DSM3645_20252	2.968e-46	178.0	COG1975@1|root,COG1975@2|Bacteria,2IXRN@203682|Planctomycetes	203682|Planctomycetes	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
YHH2_k127_3531158_3	240016.ABIZ01000001_gene3878	1.615e-32	135.0	COG2068@1|root,COG2068@2|Bacteria	2|Bacteria	NU	MobA-Related Protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
YHH2_k127_3531158_2	485914.Hmuk_2114	5.085e-36	156.0	COG3428@1|root,arCOG04619@2157|Archaea,2XU23@28890|Euryarchaeota,23T8S@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
YHH2_k127_3531158_8	1550073.JROH01000001_gene517	8.857e-23	106.0	COG3402@1|root,COG3402@2|Bacteria,1N8GD@1224|Proteobacteria,2UEFP@28211|Alphaproteobacteria,2KE76@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
YHH2_k127_3531158_0	443143.GM18_1310	7.523e-163	539.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria	2|Bacteria	QT	Acyl-homoserine-lactone synthase	-	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AIRS,Acetyltransf_10,Acetyltransf_5,Aminotran_5
YHH2_k127_3531158_4	1033734.CAET01000032_gene4217	2.953e-31	130.0	COG0344@1|root,COG0344@2|Bacteria,1VAFC@1239|Firmicutes,4HMJZ@91061|Bacilli,1ZHAN@1386|Bacillus	91061|Bacilli	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY1	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
YHH2_k127_3531158_5	452637.Oter_1808	2.475e-29	121.0	COG2378@1|root,COG2378@2|Bacteria,46VG3@74201|Verrucomicrobia,3K846@414999|Opitutae	414999|Opitutae	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
YHH2_k127_3600927_2	56110.Oscil6304_2662	1.264e-67	242.0	COG0438@1|root,COG0438@2|Bacteria,1G2DD@1117|Cyanobacteria,1HEY0@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferase 4-like domain	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH2_k127_3600927_5	497964.CfE428DRAFT_4678	1.969e-10	69.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,CarboxypepD_reg,He_PIG,LysM,PSII_BNR,SLH,TIG,fn3
YHH2_k127_3600927_9	317013.NY99_04300	6.191e-07	61.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1X38D@135614|Xanthomonadales	135614|Xanthomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
YHH2_k127_3600927_4	489825.LYNGBM3L_21140	1.832e-21	106.0	COG1216@1|root,COG1216@2|Bacteria,1FZX3@1117|Cyanobacteria,1HA1F@1150|Oscillatoriales	2|Bacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc,Glyco_tranf_2_3,Glycos_transf_2
YHH2_k127_3600927_3	1267535.KB906767_gene1239	1.495e-27	130.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_7,DLH,Peptidase_S9
YHH2_k127_3600927_1	313628.LNTAR_06999	2.541e-81	280.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
YHH2_k127_3600927_7	926556.Echvi_4189	1.854e-08	61.0	COG2963@1|root,COG2963@2|Bacteria,4NP72@976|Bacteroidetes	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
YHH2_k127_3600927_0	234267.Acid_4010	1.268e-136	452.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
YHH2_k127_3600927_8	1123242.JH636434_gene5121	4.035e-07	58.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_3600927_6	479431.Namu_1179	6.524e-10	66.0	COG4188@1|root,COG4188@2|Bacteria,2I6N2@201174|Actinobacteria	201174|Actinobacteria	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
YHH2_k127_3692831_5	452637.Oter_0402	0.0005206	47.0	COG1191@1|root,COG1191@2|Bacteria,46TPW@74201|Verrucomicrobia,3K7F7@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH2_k127_3692831_1	1123070.KB899252_gene961	5.56e-159	507.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH2_k127_3692831_4	696369.KI912183_gene2911	1.612e-33	139.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,260H4@186807|Peptococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
YHH2_k127_3692831_2	1156937.MFUM_290012	4.249e-108	373.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,37G03@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Peptidase_M56,Transpeptidase
YHH2_k127_3692831_3	794903.OPIT5_07350	6.557e-84	292.0	COG0772@1|root,COG0772@2|Bacteria,46SQT@74201|Verrucomicrobia,3K7H4@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
YHH2_k127_3692831_0	497964.CfE428DRAFT_3932	1.124e-196	632.0	COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
YHH2_k127_3726658_4	251229.Chro_0879	1.935e-72	256.0	COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria,3VKAC@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH2_k127_3726658_2	489825.LYNGBM3L_21170	1.583e-134	438.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YHH2_k127_3726658_7	1121106.JQKB01000005_gene2064	4.502e-25	119.0	COG0500@1|root,COG0500@2|Bacteria,1NT9Y@1224|Proteobacteria,2UQEZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
YHH2_k127_3726658_0	335543.Sfum_3551	3.254e-176	559.0	COG0438@1|root,COG0438@2|Bacteria,1RAGT@1224|Proteobacteria,42Y8X@68525|delta/epsilon subdivisions,2WU97@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3726658_6	1123248.KB893322_gene634	6.496e-40	157.0	COG0110@1|root,COG0110@2|Bacteria,4NVA6@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
YHH2_k127_3726658_5	1123248.KB893322_gene635	1.834e-41	164.0	COG0110@1|root,COG0110@2|Bacteria,4NVA6@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
YHH2_k127_3726658_1	335543.Sfum_3555	2.336e-137	458.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WTQK@28221|Deltaproteobacteria,2MSIN@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH2_k127_3726658_3	489825.LYNGBM3L_21200	9.385e-93	309.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH2_k127_3761158_4	234267.Acid_4124	3.258e-31	142.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
YHH2_k127_3761158_5	395495.Lcho_3739	5.41e-15	85.0	COG0689@1|root,COG5276@1|root,COG0689@2|Bacteria,COG5276@2|Bacteria,1QVI5@1224|Proteobacteria	1224|Proteobacteria	N	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,He_PIG,LVIVD
YHH2_k127_3761158_6	1337936.IJ00_22680	6.835e-12	76.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,DUF4625,NPCBM_assoc,PEGA
YHH2_k127_3761158_0	481448.Minf_0011	6.769e-160	514.0	COG0104@1|root,COG0104@2|Bacteria,46TDF@74201|Verrucomicrobia,37GDA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
YHH2_k127_3761158_2	1403819.BATR01000184_gene6352	2.951e-87	295.0	COG0020@1|root,COG0020@2|Bacteria,46SMY@74201|Verrucomicrobia,2IU5V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
YHH2_k127_3761158_3	497964.CfE428DRAFT_4834	1.02e-52	198.0	COG4589@1|root,COG4589@2|Bacteria,46SX9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
YHH2_k127_3761158_1	1403819.BATR01000096_gene3146	3.389e-129	424.0	COG0743@1|root,COG0743@2|Bacteria,46S90@74201|Verrucomicrobia,2ITI1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
YHH2_k127_3775335_6	396595.TK90_2499	7.401e-08	64.0	COG0457@1|root,COG3118@1|root,COG5010@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG5010@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,1WX1E@135613|Chromatiales	135613|Chromatiales	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
YHH2_k127_3775335_3	926549.KI421517_gene360	7.44e-84	286.0	COG5507@1|root,COG5507@2|Bacteria,4NJE8@976|Bacteroidetes,47NID@768503|Cytophagia	976|Bacteroidetes	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
YHH2_k127_3775335_5	478741.JAFS01000002_gene851	1.883e-33	140.0	COG0095@1|root,COG0095@2|Bacteria,46T01@74201|Verrucomicrobia,37GRJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YHH2_k127_3775335_1	452637.Oter_0935	2.167e-161	515.0	COG0042@1|root,COG0042@2|Bacteria,46TCT@74201|Verrucomicrobia,3K895@414999|Opitutae	414999|Opitutae	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
YHH2_k127_3775335_4	794903.OPIT5_25600	6.451e-79	269.0	COG1136@1|root,COG1136@2|Bacteria,46XY5@74201|Verrucomicrobia,3K8M1@414999|Opitutae	414999|Opitutae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_3775335_2	794903.OPIT5_09095	1.134e-131	432.0	COG0577@1|root,COG0577@2|Bacteria,46TQK@74201|Verrucomicrobia,3K8BY@414999|Opitutae	414999|Opitutae	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_3775335_0	344747.PM8797T_02844	1.268e-171	552.0	COG3420@1|root,COG3420@2|Bacteria,2J2QH@203682|Planctomycetes	203682|Planctomycetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH2_k127_3778265_6	382464.ABSI01000020_gene121	3.924e-11	68.0	COG0500@1|root,COG0500@2|Bacteria,46YTR@74201|Verrucomicrobia,2IU3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Response_reg
YHH2_k127_3778265_2	1192124.LIG30_1904	2.599e-59	224.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2VMG2@28216|Betaproteobacteria,1K0VE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
YHH2_k127_3778265_5	998674.ATTE01000001_gene2703	2.188e-36	151.0	COG2898@1|root,COG2898@2|Bacteria,1N1JA@1224|Proteobacteria,1S7E5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2156
YHH2_k127_3778265_1	349521.HCH_05076	3.345e-74	261.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ycjY	GO:0008150,GO:0009987,GO:0051301	-	ko:K01990,ko:K06889	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DLH,Hydrolase_4,Peptidase_S15
YHH2_k127_3778265_3	398767.Glov_2787	8.48e-46	179.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
YHH2_k127_3778265_4	382464.ABSI01000012_gene2004	8.357e-42	158.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia,2IUN6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YHH2_k127_3778265_0	1123242.JH636435_gene2024	7.888e-171	588.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8,WD40
YHH2_k127_3802420_6	497964.CfE428DRAFT_4932	4.001e-46	168.0	COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YHH2_k127_3802420_7	477974.Daud_1621	5.896e-46	170.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,261RG@186807|Peptococcaceae	186801|Clostridia	E	belongs to the PRA-CH family	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
YHH2_k127_3802420_0	794903.OPIT5_20520	9.277e-171	550.0	COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,3K72I@414999|Opitutae	414999|Opitutae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
YHH2_k127_3802420_12	497964.CfE428DRAFT_4116	6.057e-22	106.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YHH2_k127_3802420_11	240016.ABIZ01000001_gene891	9.099e-26	112.0	COG2860@1|root,COG2860@2|Bacteria,46T5E@74201|Verrucomicrobia,2IUJG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
YHH2_k127_3802420_14	889378.Spiaf_1653	5.256e-17	84.0	2EH48@1|root,33AW7@2|Bacteria,2J921@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3802420_5	608538.HTH_1469	1.395e-51	190.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
YHH2_k127_3802420_2	452637.Oter_1728	4.939e-114	386.0	COG0642@1|root,COG2205@2|Bacteria,46TKR@74201|Verrucomicrobia,3K7YS@414999|Opitutae	452637.Oter_1728|-	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3802420_4	1121438.JNJA01000001_gene2064	8.219e-94	313.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,2MA2P@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_3802420_1	452637.Oter_1726	3.679e-166	537.0	COG0265@1|root,COG0265@2|Bacteria,46UW8@74201|Verrucomicrobia,3K7DR@414999|Opitutae	2|Bacteria	M	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH2_k127_3802420_8	1384066.JAGT01000001_gene1122	5.367e-37	150.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia,3WGSS@541000|Ruminococcaceae	186801|Clostridia	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
YHH2_k127_3802420_3	1396418.BATQ01000025_gene5262	8.953e-108	361.0	COG0520@1|root,COG0520@2|Bacteria,46SC0@74201|Verrucomicrobia,2IW1B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YHH2_k127_3802420_13	497964.CfE428DRAFT_3686	1.27e-17	94.0	COG1459@1|root,COG1459@2|Bacteria,46VYX@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
YHH2_k127_3802420_9	1089550.ATTH01000001_gene2110	9.987e-37	142.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1FJEP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YHH2_k127_3802915_7	452637.Oter_2549	8.529e-47	172.0	COG0704@1|root,COG0704@2|Bacteria,46SUX@74201|Verrucomicrobia,3K824@414999|Opitutae	414999|Opitutae	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
YHH2_k127_3802915_4	523791.Kkor_2096	6.831e-111	374.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1XHJU@135619|Oceanospirillales	135619|Oceanospirillales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
YHH2_k127_3802915_0	671143.DAMO_1101	4.511e-180	583.0	COG0581@1|root,COG0581@2|Bacteria,2NPJS@2323|unclassified Bacteria	2|Bacteria	P	phosphate transport system permease protein	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YHH2_k127_3802915_1	237368.SCABRO_01119	9.725e-169	556.0	COG4590@1|root,COG4590@2|Bacteria,2J4XR@203682|Planctomycetes	203682|Planctomycetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
YHH2_k127_3802915_3	305700.B447_17883	3.349e-120	396.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,2VTJU@28216|Betaproteobacteria,2KZ2U@206389|Rhodocyclales	206389|Rhodocyclales	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
YHH2_k127_3802915_8	247634.GPB2148_3470	6.729e-27	125.0	COG2188@1|root,COG2188@2|Bacteria,1QVF7@1224|Proteobacteria,1S5D3@1236|Gammaproteobacteria,1J8FY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Putative porin	-	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Porin_5
YHH2_k127_3802915_6	1121101.HMPREF1532_01865	1.763e-58	229.0	2C2C5@1|root,2ZBHC@2|Bacteria,4NU14@976|Bacteroidetes,2FQDI@200643|Bacteroidia,4ANYK@815|Bacteroidaceae	976|Bacteroidetes	G	hydrolase activity, acting on glycosyl bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3802915_9	196162.Noca_3960	1.699e-12	81.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4DWZ8@85009|Propionibacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH2_k127_3802915_5	1957.JODX01000028_gene5848	6.707e-71	250.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_3802915_2	240016.ABIZ01000001_gene3199	5.894e-142	460.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_3824337_0	497964.CfE428DRAFT_5970	1.515e-263	824.0	COG1217@1|root,COG1217@2|Bacteria,46SHA@74201|Verrucomicrobia	74201|Verrucomicrobia	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
YHH2_k127_3824337_3	452637.Oter_3096	5.569e-143	462.0	COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,3K7BN@414999|Opitutae	414999|Opitutae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YHH2_k127_3824337_4	382464.ABSI01000013_gene1727	1.863e-62	224.0	COG1388@1|root,COG1388@2|Bacteria,46T61@74201|Verrucomicrobia	74201|Verrucomicrobia	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LysM
YHH2_k127_3824337_5	935863.AWZR01000004_gene677	3.424e-56	208.0	COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,1S1R3@1236|Gammaproteobacteria,1X47H@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF2167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
YHH2_k127_3824337_13	1403819.BATR01000054_gene1699	8.933e-19	99.0	2C9T2@1|root,347D0@2|Bacteria,46XSF@74201|Verrucomicrobia,2IWGU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3824337_17	314345.SPV1_09453	1.984e-05	53.0	COG2331@1|root,COG2331@2|Bacteria,1NGTT@1224|Proteobacteria	1224|Proteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH2_k127_3824337_8	497964.CfE428DRAFT_2435	4.275e-47	180.0	COG0546@1|root,COG0546@2|Bacteria,46SW1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2
YHH2_k127_3824337_15	1265505.ATUG01000001_gene3561	3.659e-12	72.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MKY4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
YHH2_k127_3824337_10	452637.Oter_2046	2.167e-27	120.0	COG0466@1|root,COG0466@2|Bacteria,46WE2@74201|Verrucomicrobia,3K9NW@414999|Opitutae	414999|Opitutae	O	PFAM peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
YHH2_k127_3824337_12	589865.DaAHT2_0949	2.319e-20	93.0	COG0296@1|root,COG0296@2|Bacteria,1NIZI@1224|Proteobacteria,42WYM@68525|delta/epsilon subdivisions,2WSNX@28221|Deltaproteobacteria,2MMER@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
YHH2_k127_3824337_1	497964.CfE428DRAFT_1483	1.512e-206	650.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_3824337_2	497964.CfE428DRAFT_0118	2.958e-143	466.0	COG1972@1|root,COG1972@2|Bacteria,46S7I@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Na dependent nucleoside transporter domain protein	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
YHH2_k127_3824337_11	292459.STH3180	1.987e-26	115.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
YHH2_k127_3824337_14	1128421.JAGA01000002_gene1039	6.915e-13	71.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2NR4E@2323|unclassified Bacteria	2|Bacteria	H	MoaE protein	moaD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.7.7.77,2.8.1.12,4.6.1.17	ko:K03635,ko:K03636,ko:K03637,ko:K03752,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395,R11372,R11581	RC02507,RC03425	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775	MoaE,ThiS
YHH2_k127_3824337_7	1297617.JPJD01000047_gene1362	5.095e-52	192.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,268EW@186813|unclassified Clostridiales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
YHH2_k127_3824337_6	278957.ABEA03000094_gene4751	1.19e-52	191.0	COG4508@1|root,COG4508@2|Bacteria,46VH7@74201|Verrucomicrobia,3K7ZP@414999|Opitutae	414999|Opitutae	S	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
YHH2_k127_3824337_9	278957.ABEA03000094_gene4754	5.521e-46	176.0	COG0811@1|root,COG0811@2|Bacteria,46SUA@74201|Verrucomicrobia,3K7EH@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH2_k127_3824337_16	656519.Halsa_1268	1.01e-05	57.0	COG0848@1|root,COG0848@2|Bacteria,1V6MA@1239|Firmicutes,24PF8@186801|Clostridia,3WASI@53433|Halanaerobiales	186801|Clostridia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH2_k127_3826369_0	272134.KB731324_gene2895	1.048e-92	336.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
YHH2_k127_3826369_3	1499967.BAYZ01000008_gene5406	2.246e-07	61.0	2EQF3@1|root,33I12@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3826369_1	1341181.FLJC2902T_20800	3.748e-24	117.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C70
YHH2_k127_3826369_2	489825.LYNGBM3L_67200	4.596e-13	82.0	COG3540@1|root,COG5276@1|root,COG3540@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,LVIVD,Laminin_G_3,Metallophos,Pur_ac_phosph_N
YHH2_k127_3839820_6	1028806.GGE_0774	1.422e-09	62.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1Y6WF@135625|Pasteurellales	135625|Pasteurellales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH2_k127_3839820_4	515635.Dtur_1559	1.204e-18	91.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	MA20_45160	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YHH2_k127_3839820_7	572547.Amico_1532	0.0006581	50.0	COG0824@1|root,COG0824@2|Bacteria,3TBBP@508458|Synergistetes	508458|Synergistetes	S	acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
YHH2_k127_3839820_1	671143.DAMO_2354	5.877e-96	323.0	COG1090@1|root,COG1090@2|Bacteria,2NPHC@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
YHH2_k127_3839820_3	497964.CfE428DRAFT_4839	2.31e-75	265.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH2_k127_3839820_2	452637.Oter_1107	5.644e-94	317.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
YHH2_k127_3839820_0	1123242.JH636435_gene793	6.047e-193	614.0	COG0415@1|root,COG0415@2|Bacteria,2IZKY@203682|Planctomycetes	203682|Planctomycetes	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
YHH2_k127_3839820_5	861299.J421_1753	1.38e-15	78.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
YHH2_k127_3866443_3	498761.HM1_0138	7.631e-26	127.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UHXK@1239|Firmicutes,25E6U@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,Flg_new,I-set,Laminin_G_3,SLH
YHH2_k127_3866443_6	1185876.BN8_03398	3.341e-08	69.0	COG2133@1|root,COG2133@2|Bacteria,4NIJA@976|Bacteroidetes,47NB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_3,PA14
YHH2_k127_3866443_1	1408433.JHXV01000026_gene3058	9.477e-41	177.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
YHH2_k127_3866443_5	864051.BurJ1DRAFT_0895	1.427e-18	103.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R1VH@1224|Proteobacteria,2WI5Y@28216|Betaproteobacteria,1KP12@119065|unclassified Burkholderiales	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,RCC1,RCC1_2,SLH,WD40
YHH2_k127_3866443_2	1121396.KB892901_gene2171	2.558e-39	172.0	COG1409@1|root,COG3291@1|root,COG4733@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,1QZGY@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,DUF839,Exo_endo_phos,PKD
YHH2_k127_3866443_0	794903.OPIT5_01350	1.246e-47	183.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YHH2_k127_3866443_4	497964.CfE428DRAFT_0420	1.449e-25	108.0	2AY99@1|root,31QBJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3916979_4	234267.Acid_4823	2.566e-35	135.0	COG2081@1|root,COG2081@2|Bacteria,3Y3KG@57723|Acidobacteria	57723|Acidobacteria	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
YHH2_k127_3916979_3	1337936.IJ00_11875	9.162e-54	216.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1GQ7T@1117|Cyanobacteria,1HJ6I@1161|Nostocales	1117|Cyanobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
YHH2_k127_3916979_1	344747.PM8797T_25041	5.725e-74	261.0	COG1082@1|root,COG1082@2|Bacteria,2IXXX@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
YHH2_k127_3916979_2	1089553.Tph_c06350	1.476e-65	235.0	COG1740@1|root,COG1740@2|Bacteria,1TZZD@1239|Firmicutes,2489B@186801|Clostridia,42FSN@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
YHH2_k127_3916979_0	931276.Cspa_c40780	4.631e-133	444.0	COG0374@1|root,COG0374@2|Bacteria,1TQMW@1239|Firmicutes,248BB@186801|Clostridia,36F7N@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hupL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
YHH2_k127_3916979_5	47763.JNZA01000012_gene6403	3.711e-14	76.0	COG0680@1|root,COG0680@2|Bacteria,2GN48@201174|Actinobacteria	201174|Actinobacteria	C	TIGRFAM hydrogenase maturation protease	hupD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
YHH2_k127_3930537_1	1968.JOEV01000010_gene1453	7.806e-95	322.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
YHH2_k127_3930537_7	118005.AWNK01000007_gene815	1.666e-09	68.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_3930537_6	395494.Galf_1544	7.726e-23	109.0	COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,2VR36@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH2_k127_3930537_10	196367.JNFG01000108_gene5398	9.38e-05	52.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VK6J@28216|Betaproteobacteria	28216|Betaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
YHH2_k127_3930537_9	1156937.MFUM_880005	3.538e-06	57.0	2BFK2@1|root,329E5@2|Bacteria,46ZB5@74201|Verrucomicrobia,37GPT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3930537_5	478741.JAFS01000001_gene1530	3.705e-27	114.0	COG2127@1|root,COG2127@2|Bacteria,46T8N@74201|Verrucomicrobia,37GW2@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
YHH2_k127_3930537_0	497964.CfE428DRAFT_4581	8.693e-152	512.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
YHH2_k127_3930537_8	313628.LNTAR_13432	2.602e-06	49.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Fer4
YHH2_k127_3930537_4	313628.LNTAR_13432	8.694e-69	243.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Fer4
YHH2_k127_3930537_3	1068978.AMETH_5365	6.153e-82	288.0	COG4030@1|root,COG4030@2|Bacteria,2GJFD@201174|Actinobacteria,4EE98@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
YHH2_k127_3930537_2	1303518.CCALI_01059	1.108e-86	304.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
YHH2_k127_3941675_1	382464.ABSI01000002_gene4290	4.006e-76	281.0	COG0457@1|root,COG0457@2|Bacteria,46X09@74201|Verrucomicrobia,2IW9W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_16,TPR_2,TPR_7,TPR_8
YHH2_k127_3941675_2	1382306.JNIM01000001_gene2595	2.562e-46	175.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YHH2_k127_3941675_3	1410616.JHXE01000014_gene454	1.797e-43	169.0	294SJ@1|root,2ZS5U@2|Bacteria,1VMUJ@1239|Firmicutes,24WT3@186801|Clostridia	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3941675_4	419947.MRA_0249	2.244e-42	160.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
YHH2_k127_3941675_0	661478.OP10G_1294	1.044e-214	699.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	F5_F8_type_C,Glyco_hydro_127
YHH2_k127_3959372_2	316067.Geob_3094	1.25e-30	128.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
YHH2_k127_3959372_0	1453500.AT05_00595	2.051e-142	457.0	COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes,1HZ0Q@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM DeoC LacD family aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
YHH2_k127_3959372_1	886293.Sinac_0940	8.577e-57	205.0	COG2234@1|root,COG2234@2|Bacteria,2IZHS@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YHH2_k127_3990090_5	714943.Mucpa_3988	3.864e-15	89.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1IQ08@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility associated	gldN	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3990090_4	1123320.KB889698_gene9323	1.418e-18	100.0	COG2133@1|root,COG3055@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,GSDH,Laminin_G_3,Malectin,PKD
YHH2_k127_3990090_3	497964.CfE428DRAFT_0900	9.29e-29	123.0	2C6YV@1|root,3392Q@2|Bacteria,46T7D@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_3990090_0	497964.CfE428DRAFT_0788	2.017e-255	795.0	COG0362@1|root,COG0362@2|Bacteria,46SDE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
YHH2_k127_3990090_6	240016.ABIZ01000001_gene1762	2.417e-08	62.0	COG3666@1|root,COG3666@2|Bacteria	2|Bacteria	-	-	tnp15	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
YHH2_k127_3990090_1	1123073.KB899243_gene738	1.419e-49	183.0	COG1392@1|root,COG1392@2|Bacteria,1PKQF@1224|Proteobacteria,1SMFE@1236|Gammaproteobacteria,1X412@135614|Xanthomonadales	135614|Xanthomonadales	P	Pit accessory protein	VL23_21310	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
YHH2_k127_3990090_7	626887.J057_22875	4.904e-08	65.0	COG2133@1|root,COG3266@1|root,COG3299@1|root,COG2133@2|Bacteria,COG3266@2|Bacteria,COG3299@2|Bacteria,1QZBF@1224|Proteobacteria,1T44G@1236|Gammaproteobacteria,4658Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	PA14	-	-	-	-	-	-	-	-	-	-	-	-	PA14,fn3
YHH2_k127_3990090_2	1218084.BBJK01000086_gene5778	4.13e-32	140.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
YHH2_k127_4003476_1	251221.35211558	2.866e-53	216.0	COG1404@1|root,COG2706@1|root,COG3391@1|root,COG1404@2|Bacteria,COG2706@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,HemolysinCabind,Peptidase_S8,TIG,VCBS
YHH2_k127_4003476_3	641112.ACOK01000050_gene3843	3.755e-18	101.0	COG5337@1|root,COG5337@2|Bacteria,1TRAW@1239|Firmicutes,24AQY@186801|Clostridia,3WHP9@541000|Ruminococcaceae	186801|Clostridia	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Dockerin_1,Fn3_assoc,LTD
YHH2_k127_4003476_4	595460.RRSWK_06974	1.487e-17	99.0	COG1404@1|root,COG3291@1|root,COG5337@1|root,COG5549@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria,COG5549@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
YHH2_k127_4003476_0	215803.DB30_7531	1.434e-126	441.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,43C2J@68525|delta/epsilon subdivisions,2X7D5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
YHH2_k127_4003476_2	794903.OPIT5_18130	3.163e-39	157.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
YHH2_k127_4021782_1	269798.CHU_2897	1.233e-70	264.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,47RAA@768503|Cytophagia	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
YHH2_k127_4021782_7	382464.ABSI01000014_gene1458	9.236e-09	65.0	2F78F@1|root,33ZPQ@2|Bacteria,46VT2@74201|Verrucomicrobia,2IURV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4021782_4	497964.CfE428DRAFT_2964	4.592e-20	94.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
YHH2_k127_4021782_2	1123517.JOMR01000001_gene1824	9.711e-54	218.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,461CZ@72273|Thiotrichales	72273|Thiotrichales	S	COGs COG0790 FOG TPR repeat SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
YHH2_k127_4021782_0	269797.Mbar_A1995	5.344e-126	445.0	arCOG02516@1|root,arCOG02538@1|root,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,2Y7RK@28890|Euryarchaeota,2NBKX@224756|Methanomicrobia	2157|Archaea	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,He_PIG,PKD,PQQ_3,Peptidase_S8,S-layer
YHH2_k127_4021782_5	553174.HMPREF0659_A7250	2.439e-18	94.0	COG3209@1|root,COG3209@2|Bacteria,4P674@976|Bacteroidetes,2FW5P@200643|Bacteroidia	976|Bacteroidetes	M	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
YHH2_k127_4021782_3	583355.Caka_1594	4.871e-30	124.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46W2M@74201|Verrucomicrobia,3K81K@414999|Opitutae	2|Bacteria	KLT	Sulfatase-modifying factor enzyme 1	egtB	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
YHH2_k127_4021782_6	1128421.JAGA01000002_gene1082	2.799e-10	64.0	COG4974@1|root,COG4974@2|Bacteria,2NRIN@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
YHH2_k127_4080116_4	234267.Acid_4124	5.174e-75	289.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
YHH2_k127_4080116_1	498211.CJA_0127	1.221e-192	666.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,1FI4C@10|Cellvibrio	1236|Gammaproteobacteria	M	Insecticide toxin TcdB middle/N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
YHH2_k127_4080116_5	395961.Cyan7425_2248	1.28e-64	235.0	COG1195@1|root,COG1195@2|Bacteria,1G1F6@1117|Cyanobacteria,3KFU9@43988|Cyanothece	1117|Cyanobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
YHH2_k127_4080116_0	1283300.ATXB01000002_gene2985	5.583e-217	684.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1XEMD@135618|Methylococcales	135618|Methylococcales	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
YHH2_k127_4080116_2	1396141.BATP01000028_gene2349	3.043e-101	343.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,46S8G@74201|Verrucomicrobia,2ITHA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
YHH2_k127_4080116_6	1121091.AUMP01000031_gene1417	0.0002898	49.0	2DSJR@1|root,33GEZ@2|Bacteria,1VPS4@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4080116_3	1173024.KI912148_gene3092	7.905e-77	264.0	COG4099@1|root,COG4099@2|Bacteria,1G426@1117|Cyanobacteria	1117|Cyanobacteria	S	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Peptidase_S9
YHH2_k127_4098737_1	163908.KB235896_gene4376	1.335e-16	81.0	COG2367@1|root,COG2367@2|Bacteria,1G0DG@1117|Cyanobacteria,1HIGK@1161|Nostocales	1117|Cyanobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
YHH2_k127_4098737_0	234267.Acid_4124	6.605e-34	148.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
YHH2_k127_4109300_1	63737.Npun_R2074	3.503e-15	87.0	2EFNF@1|root,339EK@2|Bacteria,1GFW8@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4109300_0	595460.RRSWK_01937	6.1e-57	207.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	F5_F8_type_C,Glyco_hyd_65N_2
YHH2_k127_4141013_1	565033.GACE_1880	8.395e-44	174.0	COG0560@1|root,arCOG01158@2157|Archaea,2XT0C@28890|Euryarchaeota,2462F@183980|Archaeoglobi	183980|Archaeoglobi	E	phosphoserine phosphatase SerB	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
YHH2_k127_4141013_0	94122.Shewana3_2924	3.003e-187	599.0	COG3104@1|root,COG3104@2|Bacteria,1P6K2@1224|Proteobacteria,1RZ5I@1236|Gammaproteobacteria,2Q8GE@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH2_k127_4150274_2	497964.CfE428DRAFT_6667	4.483e-104	348.0	COG1082@1|root,COG1082@2|Bacteria,46UG0@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_4150274_6	573061.Clocel_1966	3.562e-41	179.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH2_k127_4150274_4	865937.Gilli_1964	1.129e-66	263.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,1I12N@117743|Flavobacteriia,2P7RA@244698|Gillisia	976|Bacteroidetes	UW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
YHH2_k127_4150274_0	1396141.BATP01000034_gene4198	4.919e-218	761.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_4150274_3	583355.Caka_1736	2.351e-78	302.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_4150274_5	497964.CfE428DRAFT_0298	1.546e-61	216.0	COG2258@1|root,COG2258@2|Bacteria,46VBP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4150274_1	344747.PM8797T_06150	1.712e-107	366.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4150274_7	452637.Oter_0903	9.021e-24	104.0	COG1917@1|root,COG1917@2|Bacteria,46WMQ@74201|Verrucomicrobia,3K8IQ@414999|Opitutae	414999|Opitutae	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YHH2_k127_4163458_2	317619.ANKN01000187_gene3793	3.073e-22	107.0	COG2304@1|root,COG4886@1|root,COG2304@2|Bacteria,COG4886@2|Bacteria,1GQN0@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4114)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114
YHH2_k127_4163458_0	1280696.ATVY01000008_gene1898	1.704e-69	247.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,4BX27@830|Butyrivibrio	186801|Clostridia	S	TIGR00268 family	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase
YHH2_k127_4163458_1	483219.LILAB_20230	3.702e-66	241.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
YHH2_k127_4163458_4	1165096.ARWF01000001_gene1780	0.0002737	51.0	COG4970@1|root,COG4970@2|Bacteria,1NA9B@1224|Proteobacteria,2VV1S@28216|Betaproteobacteria,2KP88@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
YHH2_k127_4163458_3	472759.Nhal_3652	2.816e-14	83.0	COG3156@1|root,COG3156@2|Bacteria,1RJRE@1224|Proteobacteria,1S6CB@1236|Gammaproteobacteria,1WW8Y@135613|Chromatiales	135613|Chromatiales	U	PFAM General secretion pathway protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
YHH2_k127_4193335_0	1396418.BATQ01000147_gene3609	1.993e-230	737.0	COG1520@1|root,COG1520@2|Bacteria,46UUP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_4193335_9	497964.CfE428DRAFT_5028	2.412e-36	144.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K06075,ko:K22296	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
YHH2_k127_4193335_1	530564.Psta_1565	2.698e-229	725.0	COG0654@1|root,COG0654@2|Bacteria,2IWSD@203682|Planctomycetes	203682|Planctomycetes	CH	xanthan lyase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
YHH2_k127_4193335_12	497964.CfE428DRAFT_2605	2.249e-21	95.0	2E99J@1|root,333HQ@2|Bacteria,46T77@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
YHH2_k127_4193335_8	383372.Rcas_2433	4.271e-51	186.0	COG2065@1|root,COG2065@2|Bacteria,2G6WS@200795|Chloroflexi,375J4@32061|Chloroflexia	32061|Chloroflexia	F	Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
YHH2_k127_4193335_5	497964.CfE428DRAFT_2607	7.188e-132	429.0	COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YHH2_k127_4193335_4	497964.CfE428DRAFT_1708	1.998e-169	540.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
YHH2_k127_4193335_2	452637.Oter_2706	3.505e-192	611.0	COG0148@1|root,COG0148@2|Bacteria,46S7N@74201|Verrucomicrobia,3K7NC@414999|Opitutae	414999|Opitutae	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
YHH2_k127_4193335_3	1499967.BAYZ01000011_gene5220	1.73e-179	571.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	-	-	6.3.4.13,6.3.5.5	ko:K01945,ko:K01955	ko00230,ko00240,ko00250,ko01100,ko01110,ko01130,map00230,map00240,map00250,map01100,map01110,map01130	M00048,M00051	R00256,R00575,R01395,R04144,R10948,R10949	RC00002,RC00010,RC00043,RC00090,RC00166,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,GARS_A,GARS_C,GARS_N
YHH2_k127_4193335_6	1499967.BAYZ01000012_gene2453	8.5e-132	434.0	COG0787@1|root,COG0787@2|Bacteria,2NP3R@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
YHH2_k127_4193335_11	929562.Emtol_1837	9.288e-27	121.0	COG2935@1|root,COG2935@2|Bacteria,4P1RD@976|Bacteroidetes,47U44@768503|Cytophagia	976|Bacteroidetes	O	PFAM Arginine-tRNA-protein transferase, C terminus	-	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	Acetyltransf_6
YHH2_k127_4193335_7	575540.Isop_3614	8.081e-120	394.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4193335_10	497964.CfE428DRAFT_4502	4.814e-32	130.0	COG0607@1|root,COG0607@2|Bacteria,46W9V@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH2_k127_4193335_13	391625.PPSIR1_29975	7.643e-07	61.0	COG1572@1|root,COG1572@2|Bacteria,1QX45@1224|Proteobacteria,42YA1@68525|delta/epsilon subdivisions,2WTP9@28221|Deltaproteobacteria,2YWVC@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH2_k127_4199951_1	756272.Plabr_3534	1.358e-67	249.0	COG1566@1|root,COG1566@2|Bacteria,2J3HT@203682|Planctomycetes	203682|Planctomycetes	V	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
YHH2_k127_4199951_0	595460.RRSWK_03471	1.129e-76	265.0	COG1657@1|root,COG1657@2|Bacteria,2J1Q5@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4261694_2	335543.Sfum_1870	1.14e-48	195.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
YHH2_k127_4261694_1	671143.DAMO_0931	3.033e-75	259.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	ubiE5	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
YHH2_k127_4261694_0	1116472.MGMO_94c00170	4.35e-100	338.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1XFAX@135618|Methylococcales	135618|Methylococcales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH2_k127_4264109_1	1492737.FEM08_22110	9.574e-26	121.0	COG2273@1|root,COG2273@2|Bacteria,4NTIB@976|Bacteroidetes	976|Bacteroidetes	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_67N
YHH2_k127_4264109_0	1492737.FEM08_22110	9.841e-63	231.0	COG2273@1|root,COG2273@2|Bacteria,4NTIB@976|Bacteroidetes	976|Bacteroidetes	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_67N
YHH2_k127_4269381_0	1396141.BATP01000022_gene331	1.033e-27	127.0	COG5184@1|root,COG5184@2|Bacteria,46XQ3@74201|Verrucomicrobia,2IWCT@203494|Verrucomicrobiae	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,He_PIG,HemolysinCabind,RCC1_2
YHH2_k127_4269381_2	1121904.ARBP01000018_gene2643	2.436e-15	89.0	COG5295@1|root,COG5295@2|Bacteria,4PHWW@976|Bacteroidetes,47ST5@768503|Cytophagia	976|Bacteroidetes	UW	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4269381_3	1396141.BATP01000007_gene5656	3.188e-05	55.0	COG2312@1|root,COG3506@1|root,COG2312@2|Bacteria,COG3506@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4269381_1	251221.35210810	2.327e-21	101.0	COG5295@1|root,COG5295@2|Bacteria,1GB93@1117|Cyanobacteria	1117|Cyanobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4298417_3	644282.Deba_3187	6.39e-38	145.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YHH2_k127_4298417_4	945713.IALB_0863	5.74e-26	115.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	hao	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114	1.7.2.6	ko:K10535	ko00910,ko01120,map00910,map01120	M00528,M00804	R10164	RC00383	ko00000,ko00001,ko00002,ko01000	-	-	-	Multi-haem_cyto
YHH2_k127_4298417_0	1173024.KI912153_gene216	0.0	1710.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JKG2@1189|Stigonemataceae	1117|Cyanobacteria	C	Domain of unknown function	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH2_k127_4298417_1	1173024.KI912153_gene217	1.159e-156	501.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1JKMZ@1189|Stigonemataceae	1117|Cyanobacteria	F	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YHH2_k127_4298417_2	452637.Oter_1440	7.835e-99	331.0	COG0583@1|root,COG0583@2|Bacteria,46TZU@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
YHH2_k127_4298417_5	1348657.M622_16335	7.915e-13	76.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria	28216|Betaproteobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YHH2_k127_4324192_4	497964.CfE428DRAFT_3991	5.515e-52	194.0	2CAZH@1|root,2Z7RU@2|Bacteria,46SY1@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
YHH2_k127_4324192_0	324602.Caur_1881	0.0	1027.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH2_k127_4324192_2	383372.Rcas_3081	1.816e-115	377.0	COG0479@1|root,COG0479@2|Bacteria,2GACG@200795|Chloroflexi,3758X@32061|Chloroflexia	32061|Chloroflexia	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
YHH2_k127_4324192_3	886293.Sinac_0400	1.265e-97	330.0	COG4249@1|root,COG4249@2|Bacteria,2IZ2A@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4324192_5	237368.SCABRO_03088	4.145e-42	171.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YHH2_k127_4324192_1	344747.PM8797T_29842	5.43e-174	561.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
YHH2_k127_4338893_2	497964.CfE428DRAFT_6294	8.025e-49	184.0	2E0WZ@1|root,32WDX@2|Bacteria,46WD0@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4338893_0	1519464.HY22_04590	2.666e-230	734.0	COG0058@1|root,COG0058@2|Bacteria,1FD8Y@1090|Chlorobi	1090|Chlorobi	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
YHH2_k127_4338893_1	497964.CfE428DRAFT_0899	1.601e-119	397.0	COG0820@1|root,COG0820@2|Bacteria,46SBD@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
YHH2_k127_4345435_2	1038862.KB893884_gene756	1.571e-16	93.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria,3JSC8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4345435_0	234267.Acid_5325	4.248e-229	715.0	COG0673@1|root,COG0673@2|Bacteria,3Y7B1@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_4345435_1	794903.OPIT5_01000	8.646e-109	381.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C,Glycos_transf_2
YHH2_k127_4362150_4	398512.JQKC01000017_gene3063	5.158e-53	212.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH2_k127_4362150_6	663610.JQKO01000019_gene3046	1.241e-18	101.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1R9FR@1224|Proteobacteria,2U76X@28211|Alphaproteobacteria,3NC43@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Methyltransf_21
YHH2_k127_4362150_3	700598.Niako_1749	2.105e-59	217.0	COG3828@1|root,COG3828@2|Bacteria,4NRZF@976|Bacteroidetes,1IVGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
YHH2_k127_4362150_5	1122604.JONR01000045_gene2507	8.597e-47	173.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,1X6Z8@135614|Xanthomonadales	135614|Xanthomonadales	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
YHH2_k127_4362150_1	864702.OsccyDRAFT_2651	6.963e-116	386.0	COG0167@1|root,COG0167@2|Bacteria,1G1C2@1117|Cyanobacteria,1H89S@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YHH2_k127_4362150_0	497964.CfE428DRAFT_6644	8.647e-232	740.0	COG1657@1|root,COG1657@2|Bacteria,46TK5@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	sqhC	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
YHH2_k127_4362150_2	1403819.BATR01000054_gene1700	7.374e-60	209.0	COG0431@1|root,COG0431@2|Bacteria,46SXE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
YHH2_k127_439426_1	1156937.MFUM_700088	3.915e-152	494.0	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,37G4E@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
YHH2_k127_439426_0	497964.CfE428DRAFT_4831	7.832e-229	725.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
YHH2_k127_439426_4	333138.LQ50_06065	7.278e-10	64.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H9RK@91061|Bacilli,1ZB6M@1386|Bacillus	91061|Bacilli	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH2_k127_439426_2	926562.Oweho_0246	1.028e-65	244.0	COG3211@1|root,COG3211@2|Bacteria,4NZ53@976|Bacteroidetes,1IN2H@117743|Flavobacteriia,2PC64@246874|Cryomorphaceae	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
YHH2_k127_439426_3	35754.JNYJ01000037_gene4692	2.459e-11	76.0	COG5295@1|root,COG5297@1|root,COG5295@2|Bacteria,COG5297@2|Bacteria,2GK92@201174|Actinobacteria,4D9YE@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,Glyco_hydro_6
YHH2_k127_442072_2	314230.DSM3645_17981	2.421e-80	288.0	COG2304@1|root,COG2304@2|Bacteria,2IY1T@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA,VWA_3
YHH2_k127_442072_3	1121957.ATVL01000012_gene756	4.949e-27	125.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,47K87@768503|Cytophagia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
YHH2_k127_442072_0	395495.Lcho_3804	5.676e-149	479.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,1KJR9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
YHH2_k127_442072_1	1387312.BAUS01000011_gene1899	2.372e-132	427.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,2KMAW@206350|Nitrosomonadales	206350|Nitrosomonadales	O	TIGRFAM sulfate ABC transporter, inner membrane subunit CysT	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
YHH2_k127_4445248_1	278957.ABEA03000041_gene2046	7.589e-38	147.0	COG3250@1|root,COG3250@2|Bacteria,46YAN@74201|Verrucomicrobia,3K989@414999|Opitutae	414999|Opitutae	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4445248_0	649638.Trad_2223	1.556e-250	783.0	COG0166@1|root,COG0166@2|Bacteria,1WIGN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
YHH2_k127_4445248_3	316067.Geob_3533	1.152e-17	89.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,43UR0@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Universal stress protein	usp-2	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
YHH2_k127_4445248_2	96561.Dole_2001	5.128e-32	126.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42M9N@68525|delta/epsilon subdivisions,2WIZR@28221|Deltaproteobacteria,2MHKG@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
YHH2_k127_4462059_1	1121451.DESAM_22758	2.751e-116	408.0	COG1215@1|root,COG1215@2|Bacteria,1P7GR@1224|Proteobacteria,43D6S@68525|delta/epsilon subdivisions,2X8DM@28221|Deltaproteobacteria,2MACQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM General secretory system II protein E domain protein	-	-	-	ko:K11740	-	-	-	-	ko00000	-	-	-	Glyco_trans_2_3,T2SSE_N
YHH2_k127_4462059_0	247490.KSU1_C1392	9.224e-189	598.0	COG1032@1|root,COG1032@2|Bacteria,2IYYP@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
YHH2_k127_4492884_1	247490.KSU1_C0526	1.003e-71	257.0	COG0265@1|root,COG0265@2|Bacteria,2IXAW@203682|Planctomycetes	203682|Planctomycetes	O	typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH2_k127_4492884_0	481448.Minf_0409	1.597e-93	316.0	COG1131@1|root,COG1131@2|Bacteria,46UAZ@74201|Verrucomicrobia,37GF1@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YHH2_k127_4492884_2	497964.CfE428DRAFT_2300	6.085e-33	138.0	COG1277@1|root,COG1277@2|Bacteria,46T0W@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	nosY	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
YHH2_k127_4508081_1	246197.MXAN_0520	4.424e-120	400.0	COG1061@1|root,COG1112@1|root,COG2852@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,COG2852@2|Bacteria,1MWMG@1224|Proteobacteria,42PMB@68525|delta/epsilon subdivisions,2WJR9@28221|Deltaproteobacteria,2Z2U9@29|Myxococcales	28221|Deltaproteobacteria	KL	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559
YHH2_k127_4508081_4	1121904.ARBP01000011_gene1522	1.195e-11	70.0	2DBP2@1|root,2ZA71@2|Bacteria,4NFFI@976|Bacteroidetes,47NDZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4508081_0	335543.Sfum_1859	3.696e-231	741.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,42Q50@68525|delta/epsilon subdivisions,2WJN7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4508081_3	1123508.JH636442_gene4323	1.202e-26	128.0	COG4409@1|root,COG4932@1|root,COG4409@2|Bacteria,COG4932@2|Bacteria,2J4JQ@203682|Planctomycetes	203682|Planctomycetes	M	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4508081_2	382464.ABSI01000005_gene1189	5.047e-60	236.0	COG2312@1|root,COG5337@1|root,COG2312@2|Bacteria,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_4557702_4	261292.Nit79A3_0969	6.549e-13	78.0	2DSEK@1|root,33FUB@2|Bacteria,1NI40@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082,VPEP
YHH2_k127_4557702_1	575540.Isop_0616	2.363e-45	176.0	COG0526@1|root,COG0526@2|Bacteria,2J06Z@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
YHH2_k127_4557702_2	688269.Theth_0580	1.124e-37	155.0	COG2045@1|root,COG2045@2|Bacteria,2GD5S@200918|Thermotogae	200918|Thermotogae	H	Belongs to the ComB family	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
YHH2_k127_4557702_0	497964.CfE428DRAFT_5454	1.634e-60	220.0	COG0122@1|root,COG0122@2|Bacteria,46SVK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	8-oxoguanine DNA glycosylase, N-terminal domain	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
YHH2_k127_4557702_3	1235803.C825_02381	1.854e-32	141.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4603740_0	1156937.MFUM_970073	5.918e-177	563.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,37GBP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH2_k127_4603740_4	671143.DAMO_2861	6.69e-33	133.0	COG0494@1|root,COG0494@2|Bacteria,2NPUY@2323|unclassified Bacteria	2|Bacteria	L	NUDIX domain	mutY	-	3.6.1.55	ko:K03574,ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX,NUDIX_4
YHH2_k127_4603740_2	497964.CfE428DRAFT_2462	5.992e-142	460.0	COG0105@1|root,COG0105@2|Bacteria,46T8K@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Nucleoside diphosphate kinase	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YHH2_k127_4603740_5	1229909.NSED_07760	1.254e-08	58.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4603740_1	264462.Bd2310	1.443e-147	483.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2MT1N@213481|Bdellovibrionales,2WJPF@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YHH2_k127_4603740_3	530564.Psta_2284	2.016e-103	343.0	COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH2_k127_4605616_0	235909.GK0780	4.479e-73	270.0	COG2801@1|root,COG2801@2|Bacteria,1UFJ5@1239|Firmicutes,4IRE7@91061|Bacilli,1WHY9@129337|Geobacillus	91061|Bacilli	L	Mu transposase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
YHH2_k127_4605616_2	1049564.TevJSym_ab01170	6.348e-07	61.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1J5WG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG3267 Type II secretory pathway, component ExeA	-	-	-	ko:K12283	-	-	-	-	ko00000,ko02044	-	-	-	AAA_22
YHH2_k127_4612197_0	1120950.KB892746_gene3435	3.042e-122	428.0	2C33Y@1|root,33VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4621020_1	1210884.HG799470_gene14441	2.783e-33	138.0	COG0515@1|root,COG0515@2|Bacteria,2IWY8@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YHH2_k127_4621020_2	794903.OPIT5_20185	6.061e-14	82.0	COG2165@1|root,COG2165@2|Bacteria,46WQM@74201|Verrucomicrobia,3K9N5@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH2_k127_4621020_3	682795.AciX8_3725	4.33e-13	83.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
YHH2_k127_4621020_0	497964.CfE428DRAFT_4864	2.877e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4630832_3	335543.Sfum_0329	5.695e-26	116.0	COG1520@1|root,COG3391@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,VWD,fn3
YHH2_k127_4630832_4	696747.NIES39_B01010	2.205e-14	83.0	COG1277@1|root,COG1277@2|Bacteria,1G09F@1117|Cyanobacteria,1H81Z@1150|Oscillatoriales	1117|Cyanobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
YHH2_k127_4630832_1	575540.Isop_3428	6.079e-66	238.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH2_k127_4630832_5	765912.Thimo_2597	1.986e-09	68.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria,1WXGN@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
YHH2_k127_4630832_2	555779.Dthio_PD0504	9.33e-47	186.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,431TI@68525|delta/epsilon subdivisions,2WWAP@28221|Deltaproteobacteria,2MB98@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc,DUF4338
YHH2_k127_4630832_0	278957.ABEA03000123_gene3446	1.469e-94	322.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia,3K7ER@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH2_k127_4645639_1	489825.LYNGBM3L_33600	3.598e-133	437.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria,1H6YM@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
YHH2_k127_4645639_0	324925.Ppha_0879	4.658e-180	569.0	COG0019@1|root,COG0019@2|Bacteria	2|Bacteria	E	diaminopimelate decarboxylase activity	ldc	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YHH2_k127_4645639_2	497964.CfE428DRAFT_0141	7.131e-63	221.0	COG1082@1|root,COG4993@1|root,COG1082@2|Bacteria,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ
YHH2_k127_4645974_2	66874.JOFS01000020_gene5422	7.785e-09	61.0	COG1554@1|root,COG1554@2|Bacteria,2GJXJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hyd_65N_2
YHH2_k127_4645974_1	693661.Arcve_1896	6.719e-14	84.0	COG1533@1|root,arCOG01290@2157|Archaea,2XTYE@28890|Euryarchaeota,2461F@183980|Archaeoglobi	183980|Archaeoglobi	L	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YHH2_k127_4645974_0	1123508.JH636447_gene7855	3.306e-54	211.0	COG0515@1|root,COG0515@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YHH2_k127_4663796_0	452637.Oter_2155	0.0	1168.0	COG2373@1|root,COG2373@2|Bacteria,46U24@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
YHH2_k127_4663796_2	886293.Sinac_3517	5.382e-121	397.0	COG3622@1|root,COG3622@2|Bacteria,2IY93@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH2_k127_4663796_1	452637.Oter_3044	1.846e-144	466.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,Ig_3,LRR_5
YHH2_k127_4723605_3	497964.CfE428DRAFT_6360	1.715e-45	169.0	COG0509@1|root,COG0509@2|Bacteria,46WCE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
YHH2_k127_4723605_0	497964.CfE428DRAFT_6359	1.095e-127	421.0	COG1104@1|root,COG1104@2|Bacteria,46SFF@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YHH2_k127_4723605_2	497964.CfE428DRAFT_3924	6.472e-63	221.0	COG0231@1|root,COG0231@2|Bacteria,46SQH@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YHH2_k127_4723605_1	1403819.BATR01000181_gene6200	5.046e-81	280.0	COG1082@1|root,COG1082@2|Bacteria,46WKR@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_4724860_7	745411.B3C1_02080	6.421e-07	59.0	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1J79H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	General secretion pathway protein J	gspJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
YHH2_k127_4724860_9	1112217.PPL19_13390	0.000321	51.0	COG4970@1|root,COG4970@2|Bacteria,1N43I@1224|Proteobacteria,1SBWS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein FimT	-	-	-	ko:K08084,ko:K08085	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
YHH2_k127_4724860_6	1388763.O165_008780	2.172e-32	132.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S69B@1236|Gammaproteobacteria,1YXTE@136845|Pseudomonas putida group	1236|Gammaproteobacteria	U	secretion pathway protein	gspG_2	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
YHH2_k127_4724860_3	1123242.JH636434_gene4812	2.672e-69	250.0	COG1459@1|root,COG1459@2|Bacteria,2IXYZ@203682|Planctomycetes	203682|Planctomycetes	U	Type 4 fimbrial assembly protein pilC	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH2_k127_4724860_0	530564.Psta_3673	1.851e-161	532.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH2_k127_4724860_5	1268237.G114_12689	2.964e-37	143.0	COG0607@1|root,COG0607@2|Bacteria,1MZ87@1224|Proteobacteria,1S98V@1236|Gammaproteobacteria,1Y5TJ@135624|Aeromonadales	135624|Aeromonadales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH2_k127_4724860_4	497964.CfE428DRAFT_6518	1.707e-48	181.0	COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
YHH2_k127_4724860_1	1414720.CBYM010000003_gene388	4.431e-93	317.0	COG0524@1|root,COG0524@2|Bacteria,1V4QY@1239|Firmicutes,24HRA@186801|Clostridia,36S3G@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH2_k127_4724860_2	497964.CfE428DRAFT_1800	2.732e-75	267.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YHH2_k127_4727547_7	497964.CfE428DRAFT_4082	1.151e-11	67.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF3472,DUF5077,Gram_pos_anchor,Reprolysin_4
YHH2_k127_4727547_5	452637.Oter_1112	2.376e-79	282.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
YHH2_k127_4727547_1	794903.OPIT5_23070	7.223e-233	734.0	COG0369@1|root,COG1151@2|Bacteria	2|Bacteria	C	hydroxylamine reductase activity	hcp	GO:0000302,GO:0001505,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0017144,GO:0034641,GO:0042133,GO:0042135,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0044237,GO:0044248,GO:0044270,GO:0046209,GO:0046210,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748,GO:2001057	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
YHH2_k127_4727547_4	765911.Thivi_1699	4.611e-83	284.0	2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,1S5UD@1236|Gammaproteobacteria,1WZ6R@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4727547_2	234267.Acid_2166	1.015e-112	380.0	COG1457@1|root,COG1457@2|Bacteria,3Y6MB@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the purine-cytosine permease (2.A.39) family	-	-	-	ko:K10974	-	-	-	-	ko00000,ko02000	2.A.39.1	-	-	Transp_cyt_pur
YHH2_k127_4727547_0	452637.Oter_2942	1.7e-234	740.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
YHH2_k127_4727547_6	452637.Oter_2943	2.53e-60	216.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652
YHH2_k127_4727547_3	243275.TDE_1723	1.536e-88	304.0	COG3525@1|root,COG3525@2|Bacteria,2J6I8@203691|Spirochaetes	203691|Spirochaetes	G	hydrolase family 20, catalytic	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
YHH2_k127_4749089_2	452637.Oter_2954	2.248e-92	320.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2954|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4749089_1	886293.Sinac_6489	6.705e-156	540.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
YHH2_k127_4749089_7	1229276.DI53_3943	0.0001383	55.0	COG3866@1|root,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
YHH2_k127_4749089_3	313606.M23134_00255	7.726e-73	276.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,47RAA@768503|Cytophagia	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
YHH2_k127_4749089_4	497964.CfE428DRAFT_4864	1.478e-54	200.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4749089_0	555779.Dthio_PD2814	2.327e-178	563.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,42PEB@68525|delta/epsilon subdivisions,2WM0Y@28221|Deltaproteobacteria,2M98D@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
YHH2_k127_4749089_5	240016.ABIZ01000001_gene4602	1.039e-29	125.0	COG0742@1|root,COG0742@2|Bacteria,46T62@74201|Verrucomicrobia,2IUEM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
YHH2_k127_4749089_6	1123242.JH636434_gene5560	2.996e-05	53.0	COG4968@1|root,COG4968@2|Bacteria,2J56W@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
YHH2_k127_4756958_0	583355.Caka_1736	1.615e-86	316.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_4756958_1	278957.ABEA03000104_gene310	1.302e-55	201.0	COG0560@1|root,COG0560@2|Bacteria,46X2A@74201|Verrucomicrobia,3K7WQ@414999|Opitutae	414999|Opitutae	E	TIGRFAM phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase
YHH2_k127_4760632_5	1121405.dsmv_0737	4.11e-11	77.0	COG1649@1|root,COG2133@1|root,COG2755@1|root,COG3023@1|root,COG3250@1|root,COG3291@1|root,COG1649@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3023@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,1R2HQ@1224|Proteobacteria,42ZN7@68525|delta/epsilon subdivisions,2WUV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
YHH2_k127_4760632_2	313606.M23134_00255	1.096e-69	268.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,47RAA@768503|Cytophagia	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
YHH2_k127_4760632_6	452637.Oter_0327	1.217e-07	66.0	COG3507@1|root,COG3507@2|Bacteria,46TKI@74201|Verrucomicrobia,3KA3C@414999|Opitutae	2|Bacteria	G	PFAM glycoside hydrolase family 62	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_4_9,CBM_6,DUF1080,DUF1349,DUF5011,Flg_new,GSDH,Glyco_hydro_43,Laminin_G_3,PKD,RicinB_lectin_2,SLH,ThuA
YHH2_k127_4760632_4	794903.OPIT5_05925	4.353e-45	178.0	COG5464@1|root,COG5464@2|Bacteria	2|Bacteria	S	double-stranded DNA endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
YHH2_k127_4760632_0	886293.Sinac_6489	6.475e-146	509.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
YHH2_k127_4760632_3	497964.CfE428DRAFT_4864	3.501e-54	198.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4760632_1	313606.M23134_00255	4.763e-75	274.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,47RAA@768503|Cytophagia	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
YHH2_k127_4767384_0	324057.Pjdr2_1481	4.177e-137	470.0	COG3408@1|root,COG3408@2|Bacteria,1UZDK@1239|Firmicutes,4HF3P@91061|Bacilli,275FP@186822|Paenibacillaceae	91061|Bacilli	G	Trehalase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YHH2_k127_4767384_1	240016.ABIZ01000001_gene528	2.204e-50	183.0	COG3119@1|root,COG3119@2|Bacteria,46ZIZ@74201|Verrucomicrobia,2IV4W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH2_k127_4789799_0	497964.CfE428DRAFT_5031	1.471e-235	738.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YHH2_k127_4789799_2	1396418.BATQ01000147_gene3607	5.182e-198	621.0	COG1541@1|root,COG1541@2|Bacteria,46UFN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4789799_1	240016.ABIZ01000001_gene1451	1.499e-226	713.0	COG1012@1|root,COG1012@2|Bacteria,46UJM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
YHH2_k127_4797935_2	240016.ABIZ01000001_gene272	2.655e-66	240.0	COG0859@1|root,COG0859@2|Bacteria,46SZK@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
YHH2_k127_4797935_3	794903.OPIT5_29490	5.653e-17	90.0	2EEN4@1|root,338G1@2|Bacteria,46T5X@74201|Verrucomicrobia,3K81C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4797935_0	497964.CfE428DRAFT_3537	1.14e-165	535.0	COG0621@1|root,COG0621@2|Bacteria,46S6B@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YHH2_k127_4797935_1	497964.CfE428DRAFT_0322	3.605e-85	291.0	COG0536@1|root,COG0536@2|Bacteria,46SBS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
YHH2_k127_4806543_2	1403819.BATR01000052_gene1571	4.224e-55	204.0	COG5360@1|root,COG5360@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
YHH2_k127_4806543_1	497964.CfE428DRAFT_4806	1.456e-138	452.0	COG0412@1|root,COG0412@2|Bacteria,46TBX@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4806543_0	497964.CfE428DRAFT_6049	3.177e-183	585.0	COG0673@1|root,COG0673@2|Bacteria,46U0A@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_4831070_4	497964.CfE428DRAFT_0270	8.686e-81	272.0	COG0176@1|root,COG0176@2|Bacteria,46TNS@74201|Verrucomicrobia	74201|Verrucomicrobia	H	PFAM Transaldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
YHH2_k127_4831070_3	497964.CfE428DRAFT_2552	1.885e-81	274.0	COG0241@1|root,COG0241@2|Bacteria,46T3Q@74201|Verrucomicrobia	74201|Verrucomicrobia	E	hydrolase, HAD-superfamily, subfamily IIIA	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_like
YHH2_k127_4831070_1	1267535.KB906767_gene2539	1.825e-91	304.0	COG0279@1|root,COG0279@2|Bacteria,3Y49P@57723|Acidobacteria,2JMTY@204432|Acidobacteriia	204432|Acidobacteriia	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
YHH2_k127_4831070_2	452637.Oter_3978	2.741e-82	283.0	COG1208@1|root,COG1208@2|Bacteria,46UUZ@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
YHH2_k127_4831070_0	452637.Oter_3977	6.209e-156	497.0	COG2605@1|root,COG2605@2|Bacteria,46UPC@74201|Verrucomicrobia	74201|Verrucomicrobia	H	GHMP kinase domain protein	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YHH2_k127_4831070_5	46234.ANA_C10464	1.72e-20	103.0	COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF1735,DUF4347,HemolysinCabind,Laminin_G_3,VCBS
YHH2_k127_4834867_2	1000565.METUNv1_02114	2.322e-17	94.0	COG3540@1|root,COG3540@2|Bacteria,1NITU@1224|Proteobacteria,2W3YR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Laminin B (Domain IV)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_B,VPEP
YHH2_k127_4834867_1	1122179.KB890442_gene1152	1.06e-44	188.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_4834867_0	1396141.BATP01000043_gene1929	4.012e-131	464.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_4877811_6	1122214.AQWH01000029_gene240	7.448e-17	80.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,2PK99@255475|Aurantimonadaceae	28211|Alphaproteobacteria	G	import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
YHH2_k127_4877811_7	1089551.KE386572_gene1627	5.792e-06	49.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,4BR8I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH2_k127_4877811_2	1089551.KE386572_gene1628	1.471e-84	291.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2TV15@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440,ko:K17203	ko02010,map02010	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	BPD_transp_2
YHH2_k127_4877811_4	478741.JAFS01000002_gene922	1.154e-24	112.0	COG1430@1|root,COG1430@2|Bacteria,46W4I@74201|Verrucomicrobia,37GW3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
YHH2_k127_4877811_1	886293.Sinac_7043	8.939e-121	400.0	COG2706@1|root,COG2706@2|Bacteria,2IY02@203682|Planctomycetes	203682|Planctomycetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
YHH2_k127_4877811_3	497964.CfE428DRAFT_1223	3.668e-31	137.0	2EMW0@1|root,33FI8@2|Bacteria,46WXX@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_4877811_0	1121904.ARBP01000007_gene2944	6.281e-150	486.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,47KYK@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_4893588_0	1123242.JH636435_gene2584	3.339e-55	206.0	COG1082@1|root,COG1082@2|Bacteria,2IXRD@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
YHH2_k127_4893588_2	153721.MYP_3858	0.0001857	51.0	COG4733@1|root,COG4733@2|Bacteria,4NY26@976|Bacteroidetes	976|Bacteroidetes	S	SPTR Putative	-	-	-	-	-	-	-	-	-	-	-	-	fn3
YHH2_k127_4893588_1	497964.CfE428DRAFT_2007	4.556e-36	145.0	COG0558@1|root,COG0558@2|Bacteria,46T66@74201|Verrucomicrobia	74201|Verrucomicrobia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YHH2_k127_4910318_7	344747.PM8797T_29173	0.0001812	47.0	COG5126@1|root,COG5126@2|Bacteria	2|Bacteria	DTZ	Ca2 -binding protein (EF-Hand superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5,P_proprotein
YHH2_k127_4910318_0	1123508.JH636442_gene3913	3.552e-79	270.0	COG0655@1|root,COG0655@2|Bacteria,2IZWH@203682|Planctomycetes	203682|Planctomycetes	S	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
YHH2_k127_4910318_3	344747.PM8797T_31028	2.89e-40	156.0	COG3449@1|root,COG3449@2|Bacteria,2J2ST@203682|Planctomycetes	203682|Planctomycetes	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
YHH2_k127_4910318_5	1123508.JH636439_gene1012	6.694e-23	104.0	COG2730@1|root,COG2730@2|Bacteria,2IWW8@203682|Planctomycetes	203682|Planctomycetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
YHH2_k127_4910318_6	204669.Acid345_3566	1.782e-20	99.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	ICMT,PEMT
YHH2_k127_4910318_1	266117.Rxyl_3138	3.046e-73	259.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YHH2_k127_4910318_2	517418.Ctha_1971	2.025e-64	246.0	COG1073@1|root,COG1506@1|root,COG1073@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	LIP,Peptidase_S9
YHH2_k127_4910318_4	1123024.AUII01000006_gene4634	4.081e-32	136.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
YHH2_k127_4923344_1	1453505.JASY01000001_gene3600	1.683e-32	147.0	COG1595@1|root,COG3291@1|root,COG4733@1|root,COG1595@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NHIK@976|Bacteroidetes,1I7M2@117743|Flavobacteriia,2NVCE@237|Flavobacterium	976|Bacteroidetes	K	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_cc,Laminin_G_3
YHH2_k127_4923344_0	391625.PPSIR1_35712	0.0	1167.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
YHH2_k127_4935775_1	497964.CfE428DRAFT_0327	1.78e-15	78.0	COG1361@1|root,COG1404@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG4733@2|Bacteria,46UDB@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF5122
YHH2_k127_4935775_0	1268622.AVS7_04060	9.066e-56	207.0	COG4733@1|root,COG4733@2|Bacteria,1QVB2@1224|Proteobacteria	1224|Proteobacteria	S	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,fn3
YHH2_k127_4935775_2	546414.Deide_10260	2.168e-15	84.0	COG3525@1|root,COG3525@2|Bacteria,1WM65@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Glycosyl hydrolase family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
YHH2_k127_4937233_3	398512.JQKC01000004_gene5249	3.818e-51	194.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,3WI29@541000|Ruminococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH2_k127_4937233_1	56110.Oscil6304_0450	9.921e-80	280.0	COG1451@1|root,COG1451@2|Bacteria,1G5F8@1117|Cyanobacteria	1117|Cyanobacteria	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	SprT-like
YHH2_k127_4937233_2	314230.DSM3645_26609	9.477e-64	228.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
YHH2_k127_4937233_0	344747.PM8797T_15161	4.585e-98	332.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_4950419_2	1392490.JHZX01000001_gene201	2.945e-38	161.0	COG1572@1|root,COG2931@1|root,COG3211@1|root,COG3540@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3211@2|Bacteria,COG3540@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia	976|Bacteroidetes	Q	twin-arginine translocation pathway signal protein	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
YHH2_k127_4950419_3	1458427.BAWN01000013_gene920	7.303e-12	68.0	COG1373@1|root,COG1373@2|Bacteria,1R3UA@1224|Proteobacteria,2VQ1T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
YHH2_k127_4950419_1	1123278.KB893533_gene140	2.676e-40	160.0	COG0697@1|root,COG0697@2|Bacteria,4NHBC@976|Bacteroidetes,47NYN@768503|Cytophagia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH2_k127_4950419_0	589865.DaAHT2_2574	3.44e-56	212.0	COG5598@1|root,COG5598@2|Bacteria,1N18H@1224|Proteobacteria,42ME6@68525|delta/epsilon subdivisions,2WKDW@28221|Deltaproteobacteria,2MIBT@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
YHH2_k127_5001480_1	1396141.BATP01000023_gene643	4.293e-174	559.0	COG1190@1|root,COG1190@2|Bacteria,46TIA@74201|Verrucomicrobia,2ITHH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YHH2_k127_5001480_0	1403819.BATR01000031_gene987	9.928e-216	713.0	COG2217@1|root,COG2217@2|Bacteria,46S53@74201|Verrucomicrobia,2ITZN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	E1-E2 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
YHH2_k127_5001480_2	240016.ABIZ01000001_gene3117	2.703e-30	127.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,2IU5T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH2_k127_5003968_1	497964.CfE428DRAFT_4940	3.623e-130	419.0	COG1099@1|root,COG1099@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
YHH2_k127_5003968_0	240016.ABIZ01000001_gene1581	2.184e-132	433.0	COG1082@1|root,COG1082@2|Bacteria,46UXT@74201|Verrucomicrobia,2ITIF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5003968_2	382464.ABSI01000021_gene384	1.936e-39	158.0	COG0382@1|root,COG0382@2|Bacteria,46WYP@74201|Verrucomicrobia,2IURC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
YHH2_k127_5024230_0	452637.Oter_0135	4.581e-108	356.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,3K7PT@414999|Opitutae	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
YHH2_k127_5024230_2	187272.Mlg_2688	1.19e-86	303.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,1SA3X@1236|Gammaproteobacteria,1WZMX@135613|Chromatiales	135613|Chromatiales	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
YHH2_k127_5024230_1	452637.Oter_2514	3.715e-91	319.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,46VP5@74201|Verrucomicrobia,3K8IM@414999|Opitutae	414999|Opitutae	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH2_k127_5034412_3	439235.Dalk_0191	2.636e-05	55.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	trxA_2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	AhpC-TSA,Thioredoxin
YHH2_k127_5034412_0	1396141.BATP01000057_gene2938	4.351e-112	387.0	COG1680@1|root,COG1680@2|Bacteria,46T7M@74201|Verrucomicrobia,2IWEF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH2_k127_5034412_1	861450.HMPREF0080_01015	4.63e-95	325.0	COG5505@1|root,COG5505@2|Bacteria,1TSC8@1239|Firmicutes,4H3W2@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
YHH2_k127_5034412_2	1123070.KB899253_gene1130	1.825e-33	136.0	2CBBS@1|root,33312@2|Bacteria,46W2R@74201|Verrucomicrobia,2IUY3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5038410_2	864051.BurJ1DRAFT_2767	4.36e-42	160.0	COG5492@1|root,COG5492@2|Bacteria,1QY8X@1224|Proteobacteria,2VJ6A@28216|Betaproteobacteria	28216|Betaproteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5038410_0	404380.Gbem_2504	3.473e-79	274.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,42KZF@68525|delta/epsilon subdivisions,2WPGW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH2_k127_5038410_4	1454007.JAUG01000027_gene2771	5.302e-12	78.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,1ITIS@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YHH2_k127_5038410_8	96561.Dole_2050	3.133e-05	51.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42Q3J@68525|delta/epsilon subdivisions,2WP5U@28221|Deltaproteobacteria,2MKDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,YwqJ-deaminase
YHH2_k127_5038410_3	1173263.Syn7502_00143	2.672e-18	87.0	COG2402@1|root,COG2402@2|Bacteria,1G7JM@1117|Cyanobacteria	1117|Cyanobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_5038410_10	46234.ANA_C13780	0.0003393	47.0	COG2402@1|root,COG2402@2|Bacteria,1G76Q@1117|Cyanobacteria,1HNHX@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
YHH2_k127_5038410_7	1120978.KB894079_gene566	9.006e-06	55.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,27FKE@186828|Carnobacteriaceae	91061|Bacilli	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH2_k127_5038410_5	211165.AJLN01000104_gene6613	2.257e-11	68.0	COG3668@1|root,COG3668@2|Bacteria,1GKJ0@1117|Cyanobacteria,1JMAM@1189|Stigonemataceae	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_5038410_9	96561.Dole_2050	7.258e-05	52.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42Q3J@68525|delta/epsilon subdivisions,2WP5U@28221|Deltaproteobacteria,2MKDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,YwqJ-deaminase
YHH2_k127_5038410_1	56110.Oscil6304_1596	2.118e-49	180.0	COG1403@1|root,COG1403@2|Bacteria,1G6Z4@1117|Cyanobacteria,1HHJ7@1150|Oscillatoriales	1117|Cyanobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
YHH2_k127_5073673_1	351160.RRC213	2.647e-10	77.0	COG3391@1|root,arCOG02544@1|root,arCOG02544@2157|Archaea,arCOG02562@2157|Archaea,2Y7T2@28890|Euryarchaeota,2NBM7@224756|Methanomicrobia	224756|Methanomicrobia	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
YHH2_k127_5073673_5	1120965.AUBV01000019_gene1142	5.998e-05	59.0	COG1572@1|root,COG3209@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,4PNJW@976|Bacteroidetes	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,DUF4465
YHH2_k127_5073673_4	192952.MM_2946	2.5e-07	67.0	COG5563@1|root,arCOG03501@2157|Archaea	192952.MM_2946|-	S	Disaggregatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5073673_3	671143.DAMO_0158	1.099e-07	68.0	COG4409@1|root,COG4409@2|Bacteria,2NQRQ@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
YHH2_k127_5073673_0	543632.JOJL01000013_gene9452	1.53e-10	78.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4D962@85008|Micromonosporales	201174|Actinobacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
YHH2_k127_5073673_2	319795.Dgeo_1165	3.672e-08	70.0	2DYHC@1|root,349QF@2|Bacteria,1WMUF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5087358_3	425104.Ssed_3618	1.872e-65	241.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YHH2_k127_5087358_2	344747.PM8797T_01124	1.777e-105	355.0	COG1680@1|root,COG1680@2|Bacteria,2IZG3@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH2_k127_5087358_0	661478.OP10G_4771	2.355e-260	839.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
YHH2_k127_5087358_1	1396418.BATQ01000166_gene1868	1.79e-208	657.0	COG0137@1|root,COG0137@2|Bacteria,46SCU@74201|Verrucomicrobia,2ITYG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
YHH2_k127_5087358_4	472759.Nhal_2660	8.058e-25	106.0	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,1SCN4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
YHH2_k127_5136164_2	497964.CfE428DRAFT_4678	1.433e-05	52.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,CarboxypepD_reg,He_PIG,LysM,PSII_BNR,SLH,TIG,fn3
YHH2_k127_5136164_1	243265.plu1711	1.822e-17	94.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,1RNUW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
YHH2_k127_5136164_0	344747.PM8797T_26590	7.871e-107	355.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YHH2_k127_5145066_6	243231.GSU1251	1.661e-18	100.0	COG1361@1|root,COG2372@1|root,COG4447@1|root,COG5184@1|root,COG1361@2|Bacteria,COG2372@2|Bacteria,COG4447@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,43VN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
YHH2_k127_5145066_4	382464.ABSI01000011_gene2595	6.098e-49	193.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	phoQ	-	2.7.13.3	ko:K07637,ko:K07638,ko:K07717	ko01503,ko02020,ko02026,map01503,map02020,map02026	M00444,M00445,M00518,M00709,M00721,M00723,M00724,M00742,M00743,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HATPase_c_3,HisKA
YHH2_k127_5145066_5	382464.ABSI01000011_gene2604	3.186e-47	176.0	COG2204@1|root,COG2204@2|Bacteria,46TZX@74201|Verrucomicrobia,2IV20@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_5145066_2	382464.ABSI01000011_gene2604	2.186e-85	289.0	COG2204@1|root,COG2204@2|Bacteria,46TZX@74201|Verrucomicrobia,2IV20@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_5145066_8	1122164.JHWF01000001_gene2009	2.021e-12	73.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1JF00@118969|Legionellales	118969|Legionellales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
YHH2_k127_5145066_1	1396141.BATP01000060_gene4695	5.859e-96	327.0	COG0546@1|root,COG1051@1|root,COG0546@2|Bacteria,COG1051@2|Bacteria,46VY5@74201|Verrucomicrobia,2IUEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,NUDIX
YHH2_k127_5145066_9	1122179.KB890451_gene4532	3.442e-10	74.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,He_PIG,Laminin_G_3,VCBS
YHH2_k127_5145066_7	1123276.KB893255_gene1852	2.288e-18	100.0	COG1577@1|root,COG4886@1|root,COG4935@1|root,COG1577@2|Bacteria,COG4886@2|Bacteria,COG4935@2|Bacteria,4PPHP@976|Bacteroidetes,47YR0@768503|Cytophagia	976|Bacteroidetes	IO	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,P_proprotein
YHH2_k127_5145066_10	1210884.HG799475_gene15276	9.51e-06	59.0	COG1572@1|root,COG2304@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	1.14.18.1,3.4.24.40	ko:K00505,ko:K01406,ko:K07004	ko00350,ko00950,ko00965,ko01100,ko01110,ko01503,ko04916,map00350,map00950,map00965,map01100,map01110,map01503,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	FG-GAP,HemolysinCabind,VCBS,VWA_2
YHH2_k127_5145066_3	497964.CfE428DRAFT_6253	6.421e-53	188.0	COG0347@1|root,COG0347@2|Bacteria,46SW8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	nitrogen regulatory protein P-II	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
YHH2_k127_5145066_0	1333856.L686_01265	1.279e-116	384.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1Z0CB@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	U	Ammonium Transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
YHH2_k127_5156451_1	452637.Oter_2257	1.408e-49	193.0	COG1651@1|root,COG4243@1|root,COG1651@2|Bacteria,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	dsbC	GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0055114,GO:0140096	5.3.4.1	ko:K01829,ko:K03673,ko:K03805,ko:K03981,ko:K12228	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko02044,ko03110	3.A.7.10.1,3.A.7.11.1	-	iE2348C_1286.E2348C_3146,iEC042_1314.EC042_3104,iECO111_1330.ECO111_0636,iECO26_1355.ECO26_0680,iEcE24377_1341.EcE24377A_0625,iEcSMS35_1347.EcSMS35_3026,iG2583_1286.G2583_0768,iPC815.YPO0891,iSFV_1184.SFV_2941,iSF_1195.SF2879,iSFxv_1172.SFxv_3158,iS_1188.S3078	DsbC_N,Thioredoxin_2,Thioredoxin_4,VKOR
YHH2_k127_5156451_0	452637.Oter_0618	3.578e-271	851.0	COG3591@1|root,COG3591@2|Bacteria,46UUQ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
YHH2_k127_5213834_3	240016.ABIZ01000001_gene1247	3.709e-08	61.0	2AVZM@1|root,31MU0@2|Bacteria,46X67@74201|Verrucomicrobia,2IUMV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5213834_1	1499967.BAYZ01000137_gene111	8.094e-44	170.0	2FGP7@1|root,348IT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5213834_0	1396141.BATP01000022_gene421	1.028e-51	192.0	2BVGP@1|root,32QVG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5213834_2	1267535.KB906767_gene233	1.755e-33	145.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF4091,DUF4114,PPC,Peptidase_C2,SASA
YHH2_k127_5248064_1	382464.ABSI01000013_gene1549	2.469e-125	455.0	COG2312@1|root,COG3211@1|root,COG2312@2|Bacteria,COG3211@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
YHH2_k127_5248064_2	583355.Caka_1736	9.007e-57	229.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_5248064_4	452637.Oter_0854	1.444e-29	139.0	COG3291@1|root,COG3291@2|Bacteria,46Z7J@74201|Verrucomicrobia,3KA3F@414999|Opitutae	2|Bacteria	S	SMART Immunoglobulin C2 type	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,Ig_3,VCBS
YHH2_k127_5248064_0	497964.CfE428DRAFT_4290	3.229e-166	533.0	COG0448@1|root,COG0448@2|Bacteria,46SG2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YHH2_k127_5248064_3	1317122.ATO12_09350	8.428e-48	176.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1HX0U@117743|Flavobacteriia,2YHBS@290174|Aquimarina	976|Bacteroidetes	M	Glutamine amidotransferases class-II	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YHH2_k127_5280524_2	1396418.BATQ01000099_gene5573	9.804e-87	292.0	COG3119@1|root,COG3119@2|Bacteria,46XAA@74201|Verrucomicrobia,2IV6B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH2_k127_5280524_0	1499967.BAYZ01000177_gene5729	4.398e-143	466.0	COG0207@1|root,COG0207@2|Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
YHH2_k127_5280524_3	1267535.KB906767_gene1026	2.627e-60	226.0	COG0673@1|root,COG0673@2|Bacteria,3Y6VS@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_5280524_4	1128421.JAGA01000001_gene2102	3.197e-15	86.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
YHH2_k127_5280524_1	595460.RRSWK_04460	3.436e-122	397.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
YHH2_k127_532213_3	886293.Sinac_0789	1.849e-29	126.0	COG1266@1|root,COG1266@2|Bacteria,2J0ZS@203682|Planctomycetes	203682|Planctomycetes	S	CAAX amino terminal protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YHH2_k127_532213_0	472759.Nhal_0193	1.189e-135	475.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales	135613|Chromatiales	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
YHH2_k127_532213_6	436308.Nmar_1250	2.741e-10	75.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Kazal_1
YHH2_k127_532213_2	1123070.KB899256_gene2167	3.514e-43	166.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia,2IUIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_532213_4	452637.Oter_3780	3.108e-17	93.0	COG5662@1|root,COG5662@2|Bacteria,46VJ8@74201|Verrucomicrobia,3K9W5@414999|Opitutae	414999|Opitutae	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_532213_5	313628.LNTAR_16593	5.185e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
YHH2_k127_5329775_0	278957.ABEA03000099_gene815	4.485e-269	844.0	COG0318@1|root,COG0318@2|Bacteria,46SG3@74201|Verrucomicrobia,3K8JV@414999|Opitutae	414999|Opitutae	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C,Acyltransferase
YHH2_k127_5329775_1	1121422.AUMW01000017_gene1962	3.361e-14	77.0	COG1872@1|root,COG1872@2|Bacteria,1VFSH@1239|Firmicutes,24T87@186801|Clostridia,262RJ@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
YHH2_k127_53328_0	240016.ABIZ01000001_gene2185	1.109e-159	511.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,2ITGY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
YHH2_k127_53328_3	452637.Oter_2549	5.436e-64	226.0	COG0704@1|root,COG0704@2|Bacteria,46SUX@74201|Verrucomicrobia,3K824@414999|Opitutae	414999|Opitutae	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
YHH2_k127_53328_2	452637.Oter_2550	2.666e-92	311.0	COG0745@1|root,COG0745@2|Bacteria,46SS3@74201|Verrucomicrobia,3K7XM@414999|Opitutae	414999|Opitutae	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_53328_1	452637.Oter_2551	2.599e-94	324.0	COG5002@1|root,COG5002@2|Bacteria,46SSA@74201|Verrucomicrobia,3K7XI@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
YHH2_k127_5342918_3	234267.Acid_2529	4.197e-28	117.0	COG3436@1|root,COG3436@2|Bacteria	2|Bacteria	L	PFAM IS66 Orf2 family protein	tnpB	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
YHH2_k127_5342918_1	1121396.KB893104_gene1783	1.302e-79	275.0	28J8Y@1|root,2Z943@2|Bacteria,1REXC@1224|Proteobacteria,43DCS@68525|delta/epsilon subdivisions,2X8IT@28221|Deltaproteobacteria,2MK0X@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4338)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4338
YHH2_k127_5342918_0	497964.CfE428DRAFT_4819	1.353e-80	300.0	COG2433@1|root,COG2433@2|Bacteria,46Z8U@74201|Verrucomicrobia	2|Bacteria	S	PFAM transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
YHH2_k127_5342918_2	768671.ThimaDRAFT_0672	2.338e-28	126.0	COG3012@1|root,COG3012@2|Bacteria,1NAMR@1224|Proteobacteria,1SJ04@1236|Gammaproteobacteria,1X1XS@135613|Chromatiales	135613|Chromatiales	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
YHH2_k127_5388102_0	1125863.JAFN01000001_gene2068	8.293e-235	754.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
YHH2_k127_5388102_4	1121033.AUCF01000001_gene2030	1.251e-79	277.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,2U66Q@28211|Alphaproteobacteria,2JRZ1@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH2_k127_5388102_1	886293.Sinac_5868	7.804e-140	463.0	COG3386@1|root,COG3386@2|Bacteria,2IXZT@203682|Planctomycetes	203682|Planctomycetes	G	gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
YHH2_k127_5388102_2	382464.ABSI01000020_gene276	5.659e-110	367.0	COG0598@1|root,COG0598@2|Bacteria,46VYH@74201|Verrucomicrobia,2IU92@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
YHH2_k127_5388102_3	439235.Dalk_3856	6.417e-106	356.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,2MJ60@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH2_k127_5388102_5	525903.Taci_0271	2.033e-13	72.0	COG0778@1|root,COG0778@2|Bacteria,3TAUI@508458|Synergistetes	508458|Synergistetes	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YHH2_k127_5394229_0	240016.ABIZ01000001_gene2328	1.605e-107	357.0	COG0141@1|root,COG0141@2|Bacteria,46SHG@74201|Verrucomicrobia,2ITG9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
YHH2_k127_5394229_1	313628.LNTAR_16798	3.71e-76	270.0	COG0079@1|root,COG0079@2|Bacteria	2|Bacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iJN678.hisC	Aminotran_1_2
YHH2_k127_5394229_2	1403819.BATR01000020_gene697	6.506e-52	201.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5394229_4	5888.CAK83508	5.23e-30	134.0	COG4642@1|root,KOG0231@2759|Eukaryota,3ZCUM@5878|Ciliophora	5878|Ciliophora	S	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN
YHH2_k127_5394229_5	401053.AciPR4_0296	2.588e-05	56.0	2DPEJ@1|root,331S0@2|Bacteria,3Y4CR@57723|Acidobacteria,2JP6H@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5394229_3	926550.CLDAP_28990	3.892e-30	125.0	COG0464@1|root,COG0464@2|Bacteria,2G87K@200795|Chloroflexi	200795|Chloroflexi	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
YHH2_k127_5395728_0	1122603.ATVI01000007_gene1801	4.536e-205	662.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1X4Q2@135614|Xanthomonadales	135614|Xanthomonadales	S	transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
YHH2_k127_5395728_4	886293.Sinac_2505	3.769e-27	116.0	2ESSA@1|root,33KAQ@2|Bacteria,2J1KK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5395728_2	243090.RB621	2.272e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YHH2_k127_5395728_3	272559.BF9343_0740	3.081e-29	135.0	28KYZ@1|root,2ZAEB@2|Bacteria,4NHBZ@976|Bacteroidetes,2FP4X@200643|Bacteroidia,4AMVW@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5395728_1	888832.HMPREF9420_0382	7.245e-98	340.0	COG0823@1|root,COG0823@2|Bacteria,4NGH4@976|Bacteroidetes,2FN8G@200643|Bacteroidia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH2_k127_5395728_5	246197.MXAN_7200	0.0001516	48.0	COG0708@1|root,COG0708@2|Bacteria,1QXVQ@1224|Proteobacteria,43C8I@68525|delta/epsilon subdivisions,2X7IX@28221|Deltaproteobacteria,2YTYF@29|Myxococcales	28221|Deltaproteobacteria	L	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,He_PIG,LTD
YHH2_k127_5411584_3	1229831.M832_01140	1.093e-08	59.0	COG1039@1|root,COG1039@2|Bacteria,2JFW4@204428|Chlamydiae	204428|Chlamydiae	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhC	-	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF3378,RNase_HII
YHH2_k127_5411584_1	497964.CfE428DRAFT_3176	1.804e-61	234.0	COG1820@1|root,COG1820@2|Bacteria,46SRF@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
YHH2_k127_5411584_2	794903.OPIT5_26370	1.784e-54	200.0	COG1714@1|root,COG1714@2|Bacteria,46Z5U@74201|Verrucomicrobia,3K8J3@414999|Opitutae	414999|Opitutae	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
YHH2_k127_5411584_0	240016.ABIZ01000001_gene1604	1.17e-207	655.0	COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,2ITMG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Anticodon binding domain	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
YHH2_k127_5414043_2	886293.Sinac_6489	3.74e-55	201.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
YHH2_k127_5414043_1	497964.CfE428DRAFT_4864	9.678e-61	218.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5414043_5	96561.Dole_0067	2.604e-12	76.0	COG0664@1|root,COG0664@2|Bacteria,1N8HF@1224|Proteobacteria,431TZ@68525|delta/epsilon subdivisions,2WTB9@28221|Deltaproteobacteria,2MP1T@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
YHH2_k127_5414043_4	575540.Isop_0990	1.355e-15	92.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,He_PIG,IAT_beta,SLH
YHH2_k127_5414043_3	1496688.ER33_07850	2.585e-16	94.0	COG2931@1|root,COG3209@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1G39H@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,HemolysinCabind,RHS_repeat
YHH2_k127_5414043_0	10224.XP_006822956.1	5.206e-67	258.0	KOG1225@1|root,KOG3594@1|root,KOG3714@1|root,KOG1219@2759|Eukaryota,KOG1225@2759|Eukaryota,KOG3594@2759|Eukaryota,KOG3714@2759|Eukaryota,KOG4289@2759|Eukaryota,38YEN@33154|Opisthokonta,3CNSM@33208|Metazoa,3E4Z0@33213|Bilateria	33208|Metazoa	T	Coagulation factor 5/8 C-terminal domain, discoidin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,F5_F8_type_C,TIG
YHH2_k127_5438653_4	1385935.N836_33310	8.418e-32	136.0	2EX6A@1|root,33QH9@2|Bacteria,1GCM4@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5438653_3	582515.KR51_00009180	4.669e-35	145.0	COG2194@1|root,COG2194@2|Bacteria,1G0XR@1117|Cyanobacteria	1117|Cyanobacteria	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5438653_5	1121904.ARBP01000028_gene1653	2.221e-17	89.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
YHH2_k127_5438653_0	344747.PM8797T_06060	1.113e-127	422.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_5438653_1	1396141.BATP01000039_gene1347	4.97e-70	243.0	COG2197@1|root,COG2197@2|Bacteria,46V5Z@74201|Verrucomicrobia,2IUBG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_5438653_2	1396141.BATP01000039_gene1348	4.23e-54	199.0	COG4585@1|root,COG4585@2|Bacteria,46V1V@74201|Verrucomicrobia,2IVY4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3
YHH2_k127_545182_2	1033732.CAHI01000007_gene2064	1.922e-05	55.0	COG3345@1|root,COG3345@2|Bacteria	2|Bacteria	G	alpha-galactosidase	rafA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
YHH2_k127_545182_1	886293.Sinac_4026	5.152e-44	167.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YHH2_k127_545182_0	452637.Oter_4175	6.001e-148	502.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YHH2_k127_5464425_8	1046714.AMRX01000006_gene2346	0.0001671	57.0	COG2372@1|root,COG5276@1|root,COG2372@2|Bacteria,COG5276@2|Bacteria,1R46A@1224|Proteobacteria,1RY7V@1236|Gammaproteobacteria,46D9Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD
YHH2_k127_5464425_5	332101.JIBU02000013_gene1351	5.537e-15	92.0	COG1361@1|root,COG1572@1|root,COG2247@1|root,COG2374@1|root,COG3386@1|root,COG4447@1|root,COG5492@1|root,COG1361@2|Bacteria,COG1572@2|Bacteria,COG2247@2|Bacteria,COG2374@2|Bacteria,COG3386@2|Bacteria,COG4447@2|Bacteria,COG5492@2|Bacteria,1V3RT@1239|Firmicutes,25BDG@186801|Clostridia,36WE8@31979|Clostridiaceae	1239|Firmicutes	MN	Carbohydrate binding domain X2	-	-	-	-	-	-	-	-	-	-	-	-	CBM_X2,CW_binding_2,Cadherin-like,Laminin_G_3,SLH
YHH2_k127_5464425_1	583355.Caka_1736	4.036e-68	268.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_5464425_7	765420.OSCT_0445	4.242e-05	59.0	COG3468@1|root,COG3468@2|Bacteria,2GBN5@200795|Chloroflexi,37785@32061|Chloroflexia	32061|Chloroflexia	MU	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
YHH2_k127_5464425_0	1396141.BATP01000006_gene5432	4.641e-119	436.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
YHH2_k127_5464425_4	865937.Gilli_1964	4.41e-23	119.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,1I12N@117743|Flavobacteriia,2P7RA@244698|Gillisia	976|Bacteroidetes	UW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
YHH2_k127_5464425_2	573061.Clocel_1966	6.33e-39	171.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH2_k127_5464425_6	497964.CfE428DRAFT_4678	5.985e-11	74.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,CarboxypepD_reg,He_PIG,LysM,PSII_BNR,SLH,TIG,fn3
YHH2_k127_5464425_3	864051.BurJ1DRAFT_0891	3.06e-32	139.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R1VH@1224|Proteobacteria,2WI5Y@28216|Betaproteobacteria,1KP12@119065|unclassified Burkholderiales	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,RCC1,RCC1_2,WD40
YHH2_k127_5468859_1	1396141.BATP01000001_gene5350	1.038e-181	578.0	COG0673@1|root,COG0673@2|Bacteria,46S77@74201|Verrucomicrobia,2IU49@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_5468859_0	886293.Sinac_0942	1.425e-209	659.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH2_k127_5491987_1	1123278.KB893408_gene18	9.107e-71	253.0	COG3391@1|root,COG3391@2|Bacteria,4NHHU@976|Bacteroidetes,47P02@768503|Cytophagia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5491987_0	1123508.JH636443_gene4823	1.767e-79	266.0	COG3119@1|root,COG3119@2|Bacteria,2IX1H@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH2_k127_5568902_0	1210884.HG799473_gene15021	1.758e-191	606.0	2BXG3@1|root,2Z82R@2|Bacteria,2IXSD@203682|Planctomycetes	203682|Planctomycetes	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
YHH2_k127_5568902_1	234267.Acid_6615	1.907e-17	94.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5568902_2	997884.HMPREF1068_04179	1.427e-15	88.0	COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,2G05U@200643|Bacteroidia,4AWF6@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 2, sugar binding domain protein	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
YHH2_k127_5575040_2	502025.Hoch_4479	2.589e-08	64.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	luxC	-	1.2.1.50	ko:K03400	ko02020,ko02024,map02020,map02024	-	R10549	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	LuxC
YHH2_k127_5575040_1	397945.Aave_4517	1.349e-55	209.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,LuxE
YHH2_k127_5575040_0	861299.J421_1753	3.619e-306	981.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
YHH2_k127_5611893_7	118005.AWNK01000001_gene1992	8.985e-43	161.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K18903	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17.3.3	-	-	OEP
YHH2_k127_5611893_6	1502851.FG93_04941	2.19e-57	213.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,3JQRQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	MA20_16810	-	-	ko:K03585,ko:K18306	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,2.A.6.2.20,2.A.6.2.32,8.A.1,8.A.1.6	-	-	HlyD_D23
YHH2_k127_5611893_0	1379698.RBG1_1C00001G1725	9.257e-253	815.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
YHH2_k127_5611893_4	344747.PM8797T_07504	3.312e-72	256.0	COG0428@1|root,COG0428@2|Bacteria,2IZ3C@203682|Planctomycetes	203682|Planctomycetes	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
YHH2_k127_5611893_5	313595.P700755_003235	5.215e-69	259.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1I4B1@117743|Flavobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH2_k127_5611893_2	382464.ABSI01000002_gene4289	1.958e-131	446.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	prsK	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c
YHH2_k127_5611893_1	382464.ABSI01000002_gene4287	2.779e-164	531.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,2ITIG@203494|Verrucomicrobiae	2|Bacteria	T	Bacterial regulatory protein, Fis family	atoC	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_5611893_3	1122915.AUGY01000043_gene7872	2.387e-96	324.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,26RSI@186822|Paenibacillaceae	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
YHH2_k127_5652846_5	1304885.AUEY01000022_gene3394	8.338e-16	83.0	COG0745@1|root,COG0745@2|Bacteria,1QW1Y@1224|Proteobacteria,43BS5@68525|delta/epsilon subdivisions,2X72Y@28221|Deltaproteobacteria,2MPJE@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,zinc_ribbon_4
YHH2_k127_5652846_0	56780.SYN_00126	6.563e-151	486.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MR4Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Type IV secretion-system coupling protein DNA-binding domain	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH2_k127_5652846_1	1304888.ATWF01000001_gene1852	8.69e-133	434.0	COG2805@1|root,COG2805@2|Bacteria,2GF8B@200930|Deferribacteres	200930|Deferribacteres	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH2_k127_5652846_2	497964.CfE428DRAFT_3333	3.882e-59	219.0	COG1565@1|root,COG1565@2|Bacteria,46T7F@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
YHH2_k127_5652846_4	497964.CfE428DRAFT_3657	1.443e-48	186.0	COG1385@1|root,COG1385@2|Bacteria,46SZQ@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
YHH2_k127_5652846_3	555088.DealDRAFT_0928	1.963e-58	208.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,42JKT@68298|Syntrophomonadaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH2_k127_5656845_1	344747.PM8797T_15461	4.76e-35	140.0	COG1914@1|root,COG1914@2|Bacteria,2J28N@203682|Planctomycetes	203682|Planctomycetes	P	H( )-stimulated, divalent metal cation uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5656845_2	1123070.KB899250_gene631	6.021e-19	89.0	2C1W8@1|root,2ZXK7@2|Bacteria,46WJJ@74201|Verrucomicrobia,2IUVQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH2_k127_5656845_0	211114.JOEF01000025_gene185	1.394e-46	188.0	COG0491@1|root,COG0491@2|Bacteria,2IBAX@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH2_k127_5665853_0	368408.Tpen_1559	2.023e-156	510.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5665853_1	234267.Acid_6082	1.748e-46	175.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	rapK	GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803	3.3.2.13,4.1.3.40,4.1.3.45	ko:K18239,ko:K18240	ko00130,ko00400,ko01100,ko01110,map00130,map00400,map01100,map01110	M00117	R01302,R10583,R10597	RC00350,RC00491,RC02148,RC03212	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribonuc_L-PSP
YHH2_k127_5669764_1	497964.CfE428DRAFT_4273	3.472e-110	365.0	COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
YHH2_k127_5669764_2	497964.CfE428DRAFT_4274	3.388e-32	128.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia	74201|Verrucomicrobia	G	TIGRFAM phosphocarrier, HPr family	fruB	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
YHH2_k127_5669764_3	913865.DOT_3901	2.454e-22	100.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,262I8@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
YHH2_k127_5669764_0	478741.JAFS01000001_gene1191	3.03e-191	608.0	COG0154@1|root,COG0154@2|Bacteria,46SCM@74201|Verrucomicrobia,37FYA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH2_k127_5721215_3	478741.JAFS01000001_gene1959	3.461e-06	61.0	COG2982@1|root,COG2982@2|Bacteria,46SSM@74201|Verrucomicrobia,37FUY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
YHH2_k127_5721215_0	247490.KSU1_C0525	2.115e-32	145.0	2DN50@1|root,32VJ4@2|Bacteria,2J04A@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
YHH2_k127_5721215_1	321332.CYB_1659	9.815e-31	138.0	COG3225@1|root,COG3225@2|Bacteria,1G0JN@1117|Cyanobacteria,1GZQ1@1129|Synechococcus	1117|Cyanobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
YHH2_k127_5721215_2	349741.Amuc_0004	1.18e-08	59.0	COG1277@1|root,COG1277@2|Bacteria,46T0W@74201|Verrucomicrobia,2IU5C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
YHH2_k127_5741109_0	1173027.Mic7113_4161	1.672e-81	310.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
YHH2_k127_5755623_0	497964.CfE428DRAFT_2154	3.257e-189	626.0	COG1674@1|root,COG1674@2|Bacteria,46SCV@74201|Verrucomicrobia	74201|Verrucomicrobia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YHH2_k127_5755623_1	1232410.KI421424_gene1610	2.362e-50	196.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
YHH2_k127_5770744_1	1082933.MEA186_30901	1.368e-91	329.0	COG1572@1|root,COG2931@1|root,COG3210@1|root,COG4070@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4070@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Cadherin-like,Calx-beta,DUF4347,He_PIG
YHH2_k127_5770744_0	316055.RPE_3791	5.558e-144	468.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,3JTZ5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	MA20_07375	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
YHH2_k127_5770744_3	481448.Minf_0355	5.461e-37	145.0	COG0526@1|root,COG0526@2|Bacteria,46SXQ@74201|Verrucomicrobia,37GRV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
YHH2_k127_5770744_2	1123508.JH636445_gene6725	2.368e-42	158.0	COG1621@1|root,COG1621@2|Bacteria,2IXNN@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 32	-	-	3.2.1.65,3.2.1.80	ko:K01212,ko:K03332	ko00051,ko00500,map00051,map00500	-	R00879,R05624,R11311	RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
YHH2_k127_5772058_0	1123073.KB899241_gene3060	2.708e-109	361.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,1XDA0@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K08137	-	-	-	-	ko00000,ko02000	2.A.1.1.1	-	-	Sugar_tr
YHH2_k127_5772058_2	1278073.MYSTI_00357	1.941e-24	106.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
YHH2_k127_5772058_1	13616.ENSMODP00000009475	2.192e-85	297.0	COG0153@1|root,KOG0631@2759|Eukaryota,38HFX@33154|Opisthokonta,3BGCU@33208|Metazoa,3CWGJ@33213|Bilateria,4835A@7711|Chordata,494MW@7742|Vertebrata,3JFIF@40674|Mammalia,4JXDA@9263|Metatheria	33208|Metazoa	G	Galactokinase 1	GALK1	GO:0000166,GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005524,GO:0005534,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006059,GO:0006066,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019200,GO:0019318,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019388,GO:0019400,GO:0019402,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019751,GO:0019752,GO:0030246,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033499,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035639,GO:0036094,GO:0042866,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0048029,GO:0051186,GO:0051188,GO:0055086,GO:0061615,GO:0061620,GO:0061622,GO:0061623,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
YHH2_k127_5772058_3	240015.ACP_1052	2.026e-24	106.0	COG2154@1|root,COG2154@2|Bacteria,3Y8QH@57723|Acidobacteria,2JNF1@204432|Acidobacteriia	204432|Acidobacteriia	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YHH2_k127_5772058_6	1146883.BLASA_3625	1.263e-08	64.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
YHH2_k127_5772058_7	452637.Oter_0732	1.573e-06	57.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	DUF2510,FHA,RDD
YHH2_k127_5772058_8	452637.Oter_0732	6.902e-06	57.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	DUF2510,FHA,RDD
YHH2_k127_5772058_4	350054.Mflv_3594	2.156e-16	85.0	2EGD2@1|root,33A4V@2|Bacteria,2I847@201174|Actinobacteria,239YB@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
YHH2_k127_5772058_5	1410630.JNKP01000003_gene1590	1.079e-10	63.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,27IHB@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
YHH2_k127_5784877_4	1122128.AUEE01000009_gene1424	1.392e-07	59.0	COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,4GYBM@90964|Staphylococcaceae	91061|Bacilli	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
YHH2_k127_5784877_1	497964.CfE428DRAFT_2401	7.03e-97	332.0	COG0006@1|root,COG0006@2|Bacteria,46SKG@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH2_k127_5784877_3	452637.Oter_3489	2.406e-55	201.0	COG2738@1|root,COG2738@2|Bacteria,46THF@74201|Verrucomicrobia,3K7WD@414999|Opitutae	414999|Opitutae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
YHH2_k127_5784877_0	497964.CfE428DRAFT_4839	5.214e-115	381.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH2_k127_5784877_2	880073.Calab_3489	1.981e-58	207.0	COG0503@1|root,COG0503@2|Bacteria,2NPGX@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	PRTase_2,Pribosyltran,TRSP
YHH2_k127_584877_1	497964.CfE428DRAFT_4171	2.959e-08	63.0	2ETM2@1|root,33M4S@2|Bacteria,46WNN@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_584877_0	530564.Psta_0688	1.938e-162	524.0	28MMN@1|root,2ZAXE@2|Bacteria,2IY1P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5889804_2	252305.OB2597_08489	3.292e-60	213.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VF8I@28211|Alphaproteobacteria,2PECP@252301|Oceanicola	28211|Alphaproteobacteria	Q	Domain of unknown function (DUF2437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
YHH2_k127_5889804_4	497964.CfE428DRAFT_0286	7.738e-44	163.0	2DR28@1|root,339V9@2|Bacteria	2|Bacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
YHH2_k127_5889804_5	794903.OPIT5_15515	1.409e-32	144.0	COG4942@1|root,COG4942@2|Bacteria,46U5A@74201|Verrucomicrobia,3K7T2@414999|Opitutae	414999|Opitutae	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5889804_3	452637.Oter_0096	2.589e-56	218.0	2EWFD@1|root,33PTV@2|Bacteria,46UNG@74201|Verrucomicrobia,3K7NI@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5889804_1	1122149.BACN01000037_gene1000	3.645e-66	237.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH2_k127_5889804_0	497964.CfE428DRAFT_2622	5.864e-122	400.0	COG0152@1|root,COG0152@2|Bacteria,46SIP@74201|Verrucomicrobia	74201|Verrucomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
YHH2_k127_5899208_3	1487953.JMKF01000050_gene1944	2.256e-06	62.0	COG2931@1|root,COG3209@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,1G2N0@1117|Cyanobacteria	1117|Cyanobacteria	Q	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,DUF4114,DUF4347,HemolysinCabind,Laminin_G_3,SBP_bac_3,VCBS
YHH2_k127_5899208_0	319225.Plut_0367	6.333e-54	220.0	COG1572@1|root,COG2304@1|root,COG2911@1|root,COG2931@1|root,COG2982@1|root,COG3210@1|root,COG3391@1|root,COG3898@1|root,COG4932@1|root,COG5276@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3898@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.2.1.65,3.4.21.10	ko:K01212,ko:K01317,ko:K12287,ko:K20276	ko00500,ko02024,map00500,map02024	-	R05624,R11311	RC03278	ko00000,ko00001,ko01000,ko01002,ko02044,ko04131	-	GH32	-	DUF4347,VCBS,VWA_2
YHH2_k127_5907176_2	1232437.KL662020_gene700	8.02e-88	311.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2MMGU@213118|Desulfobacterales	28221|Deltaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH2_k127_5907176_5	1210884.HG799466_gene12641	2.424e-39	166.0	COG1538@1|root,COG1538@2|Bacteria,2IXIW@203682|Planctomycetes	203682|Planctomycetes	MU	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH2_k127_5907176_1	756272.Plabr_1917	5.341e-96	319.0	COG3828@1|root,COG3828@2|Bacteria,2J1T0@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_5907176_4	1156937.MFUM_290031	6.506e-59	216.0	COG4974@1|root,COG4974@2|Bacteria,46SQ4@74201|Verrucomicrobia,37GJH@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH2_k127_5907176_0	1396418.BATQ01000019_gene5009	1.083e-155	510.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,2ITWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YHH2_k127_5907176_3	1341181.FLJC2902T_15110	2.886e-76	282.0	COG3386@1|root,COG3386@2|Bacteria,4PKPT@976|Bacteroidetes,1IKDI@117743|Flavobacteriia,2P0DY@237|Flavobacterium	976|Bacteroidetes	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
YHH2_k127_5907176_6	1396141.BATP01000043_gene1929	7.137e-10	72.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_591224_2	643473.KB235930_gene2249	1.015e-25	111.0	COG2402@1|root,COG2402@2|Bacteria,1G76Q@1117|Cyanobacteria,1HNHX@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
YHH2_k127_591224_3	113355.CM001775_gene2726	6.465e-05	48.0	2C6I5@1|root,3349A@2|Bacteria,1G9SW@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_591224_0	1449126.JQKL01000010_gene433	5.176e-45	175.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,2681E@186813|unclassified Clostridiales	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
YHH2_k127_591224_1	580332.Slit_2734	2.069e-28	119.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,44V19@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH2_k127_59222_5	768671.ThimaDRAFT_4485	2.115e-17	95.0	COG0265@1|root,COG1075@1|root,COG2304@1|root,COG0265@2|Bacteria,COG1075@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	MA20_07505	-	1.1.3.6,1.6.5.3,3.4.21.107	ko:K00337,ko:K03333,ko:K04771,ko:K07114	ko00190,ko00984,ko01100,ko01120,ko01503,ko02020,map00190,map00984,map01100,map01120,map01503,map02020	M00144,M00728	R01459,R11945	RC00061,RC00146	ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03110	1.A.13.2.2,1.A.13.2.3,3.D.1	-	-	DUF1194
YHH2_k127_59222_6	1218074.BAXZ01000015_gene3173	1.289e-08	67.0	COG2335@1|root,COG2335@2|Bacteria,1MZ8G@1224|Proteobacteria,2VUKM@28216|Betaproteobacteria,1K8AB@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM CHRD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
YHH2_k127_59222_2	525904.Tter_0870	6.516e-128	427.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
YHH2_k127_59222_3	452637.Oter_1417	4.153e-50	193.0	COG0795@1|root,COG0795@2|Bacteria,46STR@74201|Verrucomicrobia,3K762@414999|Opitutae	414999|Opitutae	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
YHH2_k127_59222_1	504472.Slin_1808	1.156e-143	464.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,4PKSV@976|Bacteroidetes,47K5G@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	BNR_2,Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YHH2_k127_59222_0	497964.CfE428DRAFT_6409	7.965e-231	785.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YHH2_k127_59222_4	497964.CfE428DRAFT_0875	3.966e-26	111.0	COG0413@1|root,COG0413@2|Bacteria,46SPN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
YHH2_k127_5928088_4	575540.Isop_3575	3.175e-49	179.0	COG0531@1|root,COG0531@2|Bacteria,2IXT5@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
YHH2_k127_5928088_3	530564.Psta_0854	1.448e-115	383.0	COG3367@1|root,COG3367@2|Bacteria,2IWX8@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
YHH2_k127_5928088_2	452637.Oter_0699	3.623e-150	489.0	COG0617@1|root,COG0617@2|Bacteria,46UER@74201|Verrucomicrobia,3K732@414999|Opitutae	414999|Opitutae	J	Polynucleotide adenylyltransferase	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
YHH2_k127_5928088_1	344747.PM8797T_00507	7.335e-251	788.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes	203682|Planctomycetes	CP	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
YHH2_k127_5928088_0	502025.Hoch_4238	5.796e-252	808.0	COG1109@1|root,COG1482@1|root,COG1109@2|Bacteria,COG1482@2|Bacteria,1MUD8@1224|Proteobacteria,42QR1@68525|delta/epsilon subdivisions,2WU24@28221|Deltaproteobacteria,2YUXK@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphomannose isomerase type I	-	-	5.3.1.8,5.4.2.8	ko:K01809,ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818,R01819	RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
YHH2_k127_5936427_3	317619.ANKN01000187_gene3793	1.777e-36	149.0	COG2304@1|root,COG4886@1|root,COG2304@2|Bacteria,COG4886@2|Bacteria,1GQN0@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4114)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114
YHH2_k127_5936427_2	1173027.Mic7113_1807	2.75e-121	398.0	COG2234@1|root,COG2234@2|Bacteria,1G1QW@1117|Cyanobacteria,1H7N7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YHH2_k127_5936427_1	1173028.ANKO01000017_gene246	8.618e-137	447.0	COG0309@1|root,COG0309@2|Bacteria,1G1Z7@1117|Cyanobacteria,1H82T@1150|Oscillatoriales	1117|Cyanobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
YHH2_k127_5936427_0	1173028.ANKO01000017_gene249	3.776e-173	552.0	COG0409@1|root,COG0409@2|Bacteria,1G0NJ@1117|Cyanobacteria,1H8DU@1150|Oscillatoriales	1117|Cyanobacteria	O	hydrogenase expression formation protein	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
YHH2_k127_5936427_4	1304883.KI912532_gene3171	4.346e-05	49.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,2VK6N@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YHH2_k127_5942133_6	1396141.BATP01000003_gene4925	1.877e-53	196.0	COG1392@1|root,COG1392@2|Bacteria,46SSJ@74201|Verrucomicrobia,2IVZ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Protein of unknown function DUF47	-	-	-	-	-	-	-	-	-	-	-	-	PhoU_div
YHH2_k127_5942133_5	686340.Metal_0042	1.389e-55	201.0	COG1392@1|root,COG1392@2|Bacteria,1PKQF@1224|Proteobacteria,1SMFE@1236|Gammaproteobacteria,1XG8F@135618|Methylococcales	135618|Methylococcales	P	Pit accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_5942133_2	497964.CfE428DRAFT_1528	1.556e-139	452.0	COG0306@1|root,COG0306@2|Bacteria,46SDP@74201|Verrucomicrobia	74201|Verrucomicrobia	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
YHH2_k127_5942133_10	450380.JPSY01000003_gene2608	8.002e-06	54.0	COG3666@1|root,COG3666@2|Bacteria,2IA0I@201174|Actinobacteria,4FRT9@85023|Microbacteriaceae	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
YHH2_k127_5942133_1	292459.STH2723	5.45e-142	472.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH2_k127_5942133_3	926550.CLDAP_22340	1.714e-126	425.0	COG1132@1|root,COG1132@2|Bacteria,2G5RP@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH2_k127_5942133_0	530564.Psta_2878	1.379e-232	767.0	COG1073@1|root,COG1073@2|Bacteria,2IXK0@203682|Planctomycetes	203682|Planctomycetes	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
YHH2_k127_5942133_9	1094715.CM001373_gene2096	2.053e-15	80.0	COG1476@1|root,COG1476@2|Bacteria,1P625@1224|Proteobacteria,1T7A7@1236|Gammaproteobacteria,1JF45@118969|Legionellales	118969|Legionellales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH2_k127_5942133_8	1122165.AUHS01000011_gene2591	7.513e-27	113.0	COG3550@1|root,COG3550@2|Bacteria,1NAM8@1224|Proteobacteria,1SD9R@1236|Gammaproteobacteria,1JES5@118969|Legionellales	118969|Legionellales	S	HipA N-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA
YHH2_k127_5942133_4	1122165.AUHS01000011_gene2590	6.118e-105	351.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,1RPQR@1236|Gammaproteobacteria,1JE69@118969|Legionellales	118969|Legionellales	S	Pfam:HipA_N	hipA_1	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	HipA_C
YHH2_k127_5942133_7	765912.Thimo_3075	7.575e-51	188.0	COG0500@1|root,COG2226@2|Bacteria,1RG8C@1224|Proteobacteria,1SSHV@1236|Gammaproteobacteria,1X1GD@135613|Chromatiales	135613|Chromatiales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH2_k127_5942133_11	1214101.BN159_7982	0.000447	53.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.144,2.1.1.197	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
YHH2_k127_594956_2	240016.ABIZ01000001_gene3117	9.245e-80	272.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,2IU5T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH2_k127_594956_1	439235.Dalk_1263	2.633e-84	286.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2MIHA@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
YHH2_k127_594956_0	1121405.dsmv_1085	1.633e-97	342.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MJFD@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
YHH2_k127_594956_3	439235.Dalk_1261	3.442e-17	94.0	2AF4E@1|root,31534@2|Bacteria,1NEPN@1224|Proteobacteria,42WGJ@68525|delta/epsilon subdivisions,2WRTJ@28221|Deltaproteobacteria,2MM2R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
YHH2_k127_596569_3	1123371.ATXH01000011_gene73	3.311e-10	63.0	COG2001@1|root,COG2001@2|Bacteria,2GGT9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
YHH2_k127_596569_1	644801.Psest_3267	2.809e-71	252.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1Z2ED@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
YHH2_k127_596569_0	583355.Caka_3065	9.296e-104	361.0	COG0768@1|root,COG0768@2|Bacteria,46SEZ@74201|Verrucomicrobia,3K799@414999|Opitutae	414999|Opitutae	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
YHH2_k127_596569_2	497964.CfE428DRAFT_2938	1.356e-60	220.0	COG0770@1|root,COG0770@2|Bacteria,46SDF@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH2_k127_5988049_4	518766.Rmar_0422	2.477e-26	110.0	COG2316@1|root,COG2316@2|Bacteria,4NU4P@976|Bacteroidetes	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
YHH2_k127_5988049_2	278957.ABEA03000020_gene1730	1.132e-72	260.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia,3K77A@414999|Opitutae	414999|Opitutae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH2_k127_5988049_3	1380394.JADL01000016_gene375	5.93e-45	171.0	COG1309@1|root,COG1309@2|Bacteria,1MUE2@1224|Proteobacteria,2TT72@28211|Alphaproteobacteria,2JU6V@204441|Rhodospirillales	204441|Rhodospirillales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
YHH2_k127_5988049_1	697281.Mahau_2948	1.858e-98	335.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia,42FW9@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
YHH2_k127_5988049_0	1303518.CCALI_02909	7.38e-101	340.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ytaP	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S15,Peptidase_S9
YHH2_k127_6004808_3	863365.XHC_1352	7.073e-17	80.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1X45Q@135614|Xanthomonadales	135614|Xanthomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH2_k127_6004808_0	1396418.BATQ01000030_gene5614	2.62e-139	456.0	COG0577@1|root,COG0577@2|Bacteria,46TQS@74201|Verrucomicrobia,2IWMB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH2_k127_6004808_2	1403819.BATR01000070_gene2106	3.819e-103	361.0	COG0845@1|root,COG0845@2|Bacteria,46WF0@74201|Verrucomicrobia	74201|Verrucomicrobia	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
YHH2_k127_6004808_1	240016.ABIZ01000001_gene5154	3.631e-108	371.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH2_k127_6005278_0	1396141.BATP01000056_gene3278	5.222e-35	157.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
YHH2_k127_6005278_2	926550.CLDAP_28350	1.035e-11	79.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,Gln_amidase,Gram_pos_anchor,YSIRK_signal,YadA_stalk
YHH2_k127_6005278_1	1121930.AQXG01000004_gene2868	4.107e-14	87.0	COG1572@1|root,COG2911@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,COG4733@2|Bacteria,4NYS6@976|Bacteroidetes,1IZ9T@117747|Sphingobacteriia	976|Bacteroidetes	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6005278_3	1396141.BATP01000003_gene4934	1.358e-05	59.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
YHH2_k127_6018463_1	1396141.BATP01000056_gene3248	4.816e-18	87.0	COG0524@1|root,COG0524@2|Bacteria,46XQ2@74201|Verrucomicrobia,2IWCQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH2_k127_6018463_0	1396418.BATQ01000113_gene4631	4.133e-110	371.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
YHH2_k127_6018463_2	1396141.BATP01000006_gene5432	5.087e-17	96.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
YHH2_k127_6018463_4	1122609.AUGT01000005_gene1921	1.081e-12	82.0	COG2373@1|root,COG4412@1|root,COG5549@1|root,COG2373@2|Bacteria,COG4412@2|Bacteria,COG5549@2|Bacteria,2H2B4@201174|Actinobacteria,4DTD3@85009|Propionibacteriales	201174|Actinobacteria	O	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5
YHH2_k127_6018463_5	555079.Toce_0796	8.961e-07	56.0	COG1410@1|root,COG1410@2|Bacteria,1UV7K@1239|Firmicutes,25CEH@186801|Clostridia,42GCU@68295|Thermoanaerobacterales	186801|Clostridia	E	Pterin binding enzyme	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
YHH2_k127_6018463_3	589865.DaAHT2_2485	1.38e-16	82.0	COG5598@1|root,COG5598@2|Bacteria	2|Bacteria	H	trimethylamine methyltransferase	mttB3	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
YHH2_k127_6020401_1	472759.Nhal_2006	2.099e-159	510.0	COG4287@1|root,COG4287@2|Bacteria,1NP5V@1224|Proteobacteria,1RS87@1236|Gammaproteobacteria,1X0VB@135613|Chromatiales	135613|Chromatiales	O	PhoPQ-activated pathogenicity-related protein	-	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
YHH2_k127_6020401_8	945713.IALB_0612	3.255e-21	104.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	rnaZ	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
YHH2_k127_6020401_3	398767.Glov_2048	2.775e-82	293.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YHH2_k127_6020401_11	521045.Kole_0258	1.482e-09	61.0	COG0230@1|root,COG0230@2|Bacteria,2GDMP@200918|Thermotogae	200918|Thermotogae	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
YHH2_k127_6020401_9	648996.Theam_0471	8.844e-15	79.0	COG0594@1|root,COG0594@2|Bacteria,2G4D4@200783|Aquificae	200783|Aquificae	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
YHH2_k127_6020401_7	762903.Pedsa_1758	2.253e-22	100.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
YHH2_k127_6020401_2	1156937.MFUM_200026	6.589e-87	310.0	COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia,37FV2@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
YHH2_k127_6020401_6	497964.CfE428DRAFT_1418	2.261e-24	108.0	COG1847@1|root,COG1847@2|Bacteria,46VYD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	R3H
YHH2_k127_6020401_12	1499967.BAYZ01000190_gene3848	2.728e-07	63.0	COG1404@1|root,COG2911@1|root,COG3121@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	-	-	-	ko:K07346,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02035,ko02044,ko03110	-	-	-	ASH,Calx-beta,PapD_N
YHH2_k127_6020401_13	1341181.FLJC2902T_10470	0.0008944	51.0	COG1345@1|root,COG2356@1|root,COG2374@1|root,COG3420@1|root,COG1345@2|Bacteria,COG2356@2|Bacteria,COG2374@2|Bacteria,COG3420@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia,2P0S4@237|Flavobacterium	976|Bacteroidetes	N	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	ASH,LTD
YHH2_k127_6020401_5	177439.DP2771	9.173e-39	154.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,42QDS@68525|delta/epsilon subdivisions,2WMQ3@28221|Deltaproteobacteria,2MJQ8@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
YHH2_k127_6020401_4	497964.CfE428DRAFT_0263	1.353e-71	252.0	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
YHH2_k127_6020401_10	1201288.M900_1405	1.57e-13	82.0	COG1280@1|root,COG1280@2|Bacteria,1N227@1224|Proteobacteria,43DA6@68525|delta/epsilon subdivisions,2WVZZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
YHH2_k127_6021186_2	1123274.KB899407_gene194	1.781e-85	298.0	COG0407@1|root,COG0407@2|Bacteria,2JA7B@203691|Spirochaetes	203691|Spirochaetes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH2_k127_6021186_1	118163.Ple7327_3743	4.206e-137	444.0	COG2008@1|root,COG2008@2|Bacteria,1G4PN@1117|Cyanobacteria	1117|Cyanobacteria	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
YHH2_k127_6021186_0	278957.ABEA03000005_gene4380	1.611e-163	524.0	COG0407@1|root,COG0407@2|Bacteria,46WW7@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH2_k127_6021186_3	247490.KSU1_D0785	2.766e-70	248.0	COG1108@1|root,COG1108@2|Bacteria	2|Bacteria	P	ABC-type Mn2 Zn2 transport systems permease components	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
YHH2_k127_6073813_2	378806.STAUR_1759	2.629e-09	63.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria	1224|Proteobacteria	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
YHH2_k127_6073813_0	497964.CfE428DRAFT_5202	2.314e-51	192.0	COG1595@1|root,COG1595@2|Bacteria,46V75@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6073813_1	344747.PM8797T_04035	6.63e-17	92.0	COG3250@1|root,COG3250@2|Bacteria,2J3T5@203682|Planctomycetes	203682|Planctomycetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_60760_0	1121930.AQXG01000003_gene2719	8.85e-105	351.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
YHH2_k127_60760_1	411477.PARMER_02594	2.411e-32	135.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_6095095_2	497964.CfE428DRAFT_1043	7.199e-10	64.0	COG0389@1|root,COG0389@2|Bacteria,46SNK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
YHH2_k127_6095095_1	794903.OPIT5_18275	9.107e-41	156.0	COG0023@1|root,COG0023@2|Bacteria,46WEQ@74201|Verrucomicrobia,3K8EV@414999|Opitutae	414999|Opitutae	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
YHH2_k127_6095095_0	1396141.BATP01000058_gene1993	4.354e-218	707.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YHH2_k127_6124608_0	1121104.AQXH01000001_gene1689	2.352e-75	259.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,1IQQC@117747|Sphingobacteriia	976|Bacteroidetes	P	Membrane protein TerC, possibly involved in tellurium resistance	-	-	-	-	-	-	-	-	-	-	-	-	TerC
YHH2_k127_6124608_1	439235.Dalk_3286	1.097e-26	121.0	2C2VF@1|root,33AUU@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4272)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4272
YHH2_k127_6124608_2	1142394.PSMK_16270	2.207e-15	87.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
YHH2_k127_6128985_0	661478.OP10G_0540	1.097e-94	339.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
YHH2_k127_613155_1	768706.Desor_3178	6.87e-76	269.0	COG5492@1|root,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,262NZ@186807|Peptococcaceae	186801|Clostridia	N	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_3,Flg_new,LRR_5
YHH2_k127_613155_5	684949.ATTJ01000002_gene388	2.089e-22	114.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
YHH2_k127_613155_2	304371.MCP_2796	2.393e-66	257.0	arCOG06738@1|root,arCOG06738@2157|Archaea	2157|Archaea	O	extracellular matrix structural constituent	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	Beta_helix,Calx-beta,CarboxypepD_reg,NosD,Peptidase_S8
YHH2_k127_613155_7	1202532.FF52_04390	1.158e-07	66.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia,2P01U@237|Flavobacterium	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
YHH2_k127_613155_4	497964.CfE428DRAFT_0064	1.242e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
YHH2_k127_613155_0	886293.Sinac_0152	2.814e-91	306.0	COG4221@1|root,COG4221@2|Bacteria,2IXHG@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH2_k127_613155_6	525904.Tter_2447	2.91e-11	77.0	COG3250@1|root,COG3250@2|Bacteria,2NQEM@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH2_k127_613155_3	357808.RoseRS_0991	8.795e-59	230.0	COG3250@1|root,COG3250@2|Bacteria,2G6ZW@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
YHH2_k127_613165_2	661478.OP10G_0590	4.854e-65	236.0	COG3940@1|root,COG3940@2|Bacteria	2|Bacteria	G	arabinan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
YHH2_k127_613165_0	497964.CfE428DRAFT_1254	0.0	1328.0	COG4581@1|root,COG4581@2|Bacteria,46STC@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
YHH2_k127_613165_1	240016.ABIZ01000001_gene2202	1.719e-103	345.0	COG1801@1|root,COG1801@2|Bacteria,46TUG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YHH2_k127_6134809_0	1123242.JH636434_gene5548	2.698e-52	199.0	COG1262@1|root,COG1262@2|Bacteria,2IZ7E@203682|Planctomycetes	203682|Planctomycetes	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
YHH2_k127_6134809_1	396588.Tgr7_2703	1.308e-05	52.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1X1FE@135613|Chromatiales	135613|Chromatiales	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4
YHH2_k127_6140369_0	762984.HMPREF9445_00244	2.859e-175	586.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia,4AP3C@815|Bacteroidaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NPCBM
YHH2_k127_6140369_2	1123508.JH636439_gene328	2.666e-27	130.0	COG3209@1|root,COG3209@2|Bacteria,2IY61@203682|Planctomycetes	203682|Planctomycetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YHH2_k127_6140369_3	76114.ebA1714	4.359e-11	70.0	2AP99@1|root,31EB9@2|Bacteria,1RM04@1224|Proteobacteria,2W2S7@28216|Betaproteobacteria,2KYW1@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6140369_1	880526.KE386488_gene1576	7.032e-81	302.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6140917_2	240016.ABIZ01000001_gene4116	1.181e-45	173.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia,2ITVU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
YHH2_k127_6140917_0	448385.sce0958	6.18e-288	917.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
YHH2_k127_6140917_3	497964.CfE428DRAFT_2283	3.892e-30	125.0	COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH2_k127_6140917_1	1396141.BATP01000003_gene5199	1.719e-166	533.0	COG1509@1|root,COG1509@2|Bacteria,46SVQ@74201|Verrucomicrobia,2ITNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Lysine-2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,LAM_C,Radical_SAM
YHH2_k127_6149020_2	518766.Rmar_0039	8.406e-40	157.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,1FK5D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
YHH2_k127_6149020_1	497964.CfE428DRAFT_2964	3.747e-63	223.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
YHH2_k127_6149020_0	886293.Sinac_2339	2.506e-97	343.0	COG4927@1|root,COG4927@2|Bacteria,2IYD9@203682|Planctomycetes	203682|Planctomycetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
YHH2_k127_6149020_3	661478.OP10G_4166	1.062e-12	77.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
YHH2_k127_6153223_0	1396141.BATP01000060_gene4727	5.069e-230	748.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
YHH2_k127_6153223_1	497964.CfE428DRAFT_0066	7.337e-74	275.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
YHH2_k127_6153223_2	349741.Amuc_1517	3.765e-44	168.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
YHH2_k127_616098_1	638301.HMPREF0444_0299	2.457e-140	490.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,27FVW@186828|Carnobacteriaceae	91061|Bacilli	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YHH2_k127_616098_4	357808.RoseRS_3392	7.975e-21	104.0	COG1413@1|root,COG1413@2|Bacteria,2G6UU@200795|Chloroflexi	200795|Chloroflexi	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
YHH2_k127_616098_5	383372.Rcas_4164	2.057e-11	76.0	2EE19@1|root,337W3@2|Bacteria,2G8U2@200795|Chloroflexi,375HC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LIM, zinc-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DA1-like
YHH2_k127_616098_3	309807.SRU_0495	8.649e-32	132.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1FJDT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
YHH2_k127_616098_0	478741.JAFS01000001_gene1300	1.727e-275	862.0	COG0556@1|root,COG0556@2|Bacteria,46SF2@74201|Verrucomicrobia,37GG7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH2_k127_616098_2	1396418.BATQ01000154_gene1023	1.179e-110	369.0	COG0492@1|root,COG0492@2|Bacteria,46SC1@74201|Verrucomicrobia,2ITP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YHH2_k127_6173275_1	1379270.AUXF01000002_gene1837	4.068e-29	119.0	COG1446@1|root,COG1446@2|Bacteria,1ZTAQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Asparaginase	-	-	3.5.1.26	ko:K01444	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Asparaginase_2
YHH2_k127_6173275_2	584708.Apau_0778	1.414e-09	67.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	3.6.1.55	ko:K03574,ko:K08296	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1
YHH2_k127_6173275_0	649638.Trad_0897	0.0	1179.0	COG0567@1|root,COG0567@2|Bacteria,1WIKA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	dehydrogenase e1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
YHH2_k127_6219332_4	713586.KB900536_gene1304	4.677e-15	78.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria	1224|Proteobacteria	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
YHH2_k127_6219332_1	1403819.BATR01000184_gene6355	1.266e-143	465.0	COG0505@1|root,COG0505@2|Bacteria,46TDX@74201|Verrucomicrobia,2ITTA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
YHH2_k127_6219332_3	794903.OPIT5_07630	3.927e-36	141.0	COG0526@1|root,COG0526@2|Bacteria,46SXQ@74201|Verrucomicrobia,3K8IG@414999|Opitutae	414999|Opitutae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
YHH2_k127_6219332_0	497964.CfE428DRAFT_2609	8.561e-161	521.0	COG0044@1|root,COG0044@2|Bacteria,46S78@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
YHH2_k127_6219332_5	1410668.JNKC01000016_gene993	0.0001663	48.0	2DES4@1|root,2ZP1M@2|Bacteria,1W3CF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6219332_2	357808.RoseRS_0181	2.267e-89	299.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH2_k127_624459_2	794903.OPIT5_02510	1.951e-103	345.0	COG4974@1|root,COG4974@2|Bacteria,46UB9@74201|Verrucomicrobia,3K9DD@414999|Opitutae	414999|Opitutae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
YHH2_k127_624459_0	497964.CfE428DRAFT_2953	1.674e-204	645.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia	74201|Verrucomicrobia	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YHH2_k127_624459_4	583355.Caka_1863	2.379e-37	147.0	COG0511@1|root,COG0511@2|Bacteria,46SXA@74201|Verrucomicrobia,3K861@414999|Opitutae	414999|Opitutae	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
YHH2_k127_624459_5	497964.CfE428DRAFT_5924	5.353e-34	144.0	COG0470@1|root,COG0470@2|Bacteria,46T6T@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
YHH2_k127_624459_6	349741.Amuc_0362	2.802e-27	115.0	2ERYI@1|root,33JHP@2|Bacteria,46WPE@74201|Verrucomicrobia,2IUEZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_624459_3	497964.CfE428DRAFT_4236	4.872e-89	300.0	COG2120@1|root,COG2120@2|Bacteria,46SP2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YHH2_k127_624459_1	1123248.KB893385_gene4912	9.29e-169	542.0	COG0363@1|root,COG0363@2|Bacteria,4P0EP@976|Bacteroidetes	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6351786_1	1396141.BATP01000043_gene1929	2.427e-51	210.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_6351786_3	203119.Cthe_0239	8.507e-29	136.0	COG5337@1|root,COG5337@2|Bacteria,1TRAW@1239|Firmicutes,24AQY@186801|Clostridia,3WI9B@541000|Ruminococcaceae	186801|Clostridia	M	Fn3 associated	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Dockerin_1,Fn3_assoc,LTD
YHH2_k127_6351786_2	1147.D082_25660	1.453e-38	167.0	COG2931@1|root,COG3204@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,1G5KY@1117|Cyanobacteria,1H6DE@1142|Synechocystis	1117|Cyanobacteria	QU	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,HemolysinCabind,VCBS
YHH2_k127_6351786_0	1396141.BATP01000042_gene1927	3.724e-56	223.0	COG1520@1|root,COG4625@1|root,COG5295@1|root,COG1520@2|Bacteria,COG4625@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
YHH2_k127_6358366_2	240016.ABIZ01000001_gene2198	1.847e-60	213.0	COG0521@1|root,COG0521@2|Bacteria,46SVJ@74201|Verrucomicrobia,2IUE2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
YHH2_k127_6358366_0	1499967.BAYZ01000012_gene2475	1.972e-118	389.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	ydjG	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0019170,GO:0055114	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
YHH2_k127_6358366_1	349741.Amuc_1932	1.164e-66	237.0	COG0251@1|root,COG0251@2|Bacteria,46V5Y@74201|Verrucomicrobia,2IW47@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
YHH2_k127_6362753_0	880073.Calab_3201	8.679e-135	440.0	COG4198@1|root,COG4198@2|Bacteria,2NNV0@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1015)	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	DUF1015
YHH2_k127_6362753_2	1444712.BN1013_01684	3.196e-49	185.0	COG0290@1|root,COG0290@2|Bacteria,2JG36@204428|Chlamydiae	204428|Chlamydiae	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
YHH2_k127_6362753_1	497964.CfE428DRAFT_2487	3.099e-55	213.0	28HQ3@1|root,2Z7XW@2|Bacteria,46U81@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
YHH2_k127_6391688_0	926550.CLDAP_17500	6.352e-92	337.0	COG2706@1|root,COG2931@1|root,COG5337@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,LTD,VCBS
YHH2_k127_6408861_1	1265845.PWEIH_07341	4.924e-19	104.0	COG0383@1|root,COG0383@2|Bacteria,1UZ6P@1239|Firmicutes,4IRP7@91061|Bacilli,26K7F@186820|Listeriaceae	91061|Bacilli	G	Glycosyl hydrolases family 38 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_38
YHH2_k127_6408861_2	2002.JOEQ01000009_gene6591	1.217e-05	59.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria,4EMNW@85012|Streptosporangiales	201174|Actinobacteria	M	Pretoxin HINT domain	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,PT-HINT,RHS_repeat,TGFb_propeptide,Tox-REase-5
YHH2_k127_6408861_0	1122931.AUAE01000028_gene113	7.692e-278	880.0	2CB8C@1|root,33T5I@2|Bacteria,4P0N1@976|Bacteroidetes,2FX4B@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6421286_0	497964.CfE428DRAFT_3795	3.004e-15	89.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6421286_1	519989.ECTPHS_01949	1.322e-06	53.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1WY99@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
YHH2_k127_6448023_3	644968.DFW101_3675	3.232e-12	69.0	COG0438@1|root,COG0859@1|root,COG0438@2|Bacteria,COG0859@2|Bacteria,1RFBZ@1224|Proteobacteria,43AIS@68525|delta/epsilon subdivisions,2WV3S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
YHH2_k127_6448023_2	1396141.BATP01000035_gene4053	6.834e-13	81.0	29ZA9@1|root,30M8M@2|Bacteria,46XI8@74201|Verrucomicrobia,2IVZI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6448023_1	497964.CfE428DRAFT_0088	8.555e-52	194.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH2_k127_6448023_0	1396418.BATQ01000116_gene4615	2.453e-171	547.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
YHH2_k127_6451826_3	1210884.HG799462_gene8438	1.169e-51	193.0	COG0859@1|root,COG0859@2|Bacteria,2IYZS@203682|Planctomycetes	203682|Planctomycetes	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	ko:K02841,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH2_k127_6451826_1	497964.CfE428DRAFT_1198	2.608e-97	323.0	COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
YHH2_k127_6451826_4	240016.ABIZ01000001_gene2409	4.901e-15	83.0	COG1254@1|root,COG1254@2|Bacteria,46W9W@74201|Verrucomicrobia,2IUZQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Acylphosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Acylphosphatase
YHH2_k127_6451826_0	1487953.JMKF01000080_gene4197	2.656e-105	351.0	COG1611@1|root,COG1611@2|Bacteria,1G0JD@1117|Cyanobacteria,1H6ZX@1150|Oscillatoriales	1117|Cyanobacteria	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH2_k127_6451826_2	644966.Tmar_2012	4.966e-54	198.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WCSJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Carbohydrate ABC transporter ATP-binding protein, CUT1 family	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
YHH2_k127_6492499_0	497964.CfE428DRAFT_5670	3.137e-179	574.0	COG0405@1|root,COG0405@2|Bacteria,46SGY@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YHH2_k127_6492499_1	1045858.Bint_1756	9.335e-157	506.0	COG1089@1|root,COG1089@2|Bacteria,2J78G@203691|Spirochaetes	203691|Spirochaetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
YHH2_k127_6492499_2	929562.Emtol_4289	1.892e-128	421.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,47KAF@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
YHH2_k127_6505675_1	497964.CfE428DRAFT_6353	2.907e-84	286.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.9,4.1.1.19	ko:K00943,ko:K01585	ko00240,ko00330,ko01100,map00240,map00330,map01100	M00053,M00133	R00566,R02094,R02098	RC00002,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
YHH2_k127_6505675_0	497964.CfE428DRAFT_6354	7.051e-87	300.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
YHH2_k127_6517696_5	497964.CfE428DRAFT_6674	3.4e-05	54.0	COG3339@1|root,COG3339@2|Bacteria,46WK3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
YHH2_k127_6517696_1	177439.DP0005	2.965e-102	341.0	COG0106@1|root,COG0106@2|Bacteria,1R6J2@1224|Proteobacteria,43B0N@68525|delta/epsilon subdivisions,2X6EQ@28221|Deltaproteobacteria,2MICV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the HisA HisF family	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YHH2_k127_6517696_2	553217.ENHAE0001_0309	6.513e-25	113.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,3NM1X@468|Moraxellaceae	1236|Gammaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
YHH2_k127_6517696_4	481448.Minf_2165	6.313e-07	59.0	2FHDV@1|root,34981@2|Bacteria,46W9B@74201|Verrucomicrobia,37GRP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6517696_0	1396418.BATQ01000046_gene6146	1.468e-131	426.0	COG0477@1|root,COG0477@2|Bacteria,46TSP@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH2_k127_6517696_3	1123242.JH636438_gene5758	2.433e-21	93.0	COG0477@1|root,COG0477@2|Bacteria,2IWYM@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
YHH2_k127_6523705_1	63737.Npun_F4763	1.849e-24	109.0	COG2402@1|root,COG2402@2|Bacteria,1G76Q@1117|Cyanobacteria,1HNHX@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
YHH2_k127_6523705_0	634499.EpC_31610	5.078e-111	389.0	COG0358@1|root,COG0358@2|Bacteria,1MWSP@1224|Proteobacteria,1RYXP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA primase	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_N,zf-CHC2
YHH2_k127_661603_2	452637.Oter_2787	9.886e-59	217.0	COG0739@1|root,COG0739@2|Bacteria,46V20@74201|Verrucomicrobia,3K74E@414999|Opitutae	414999|Opitutae	M	Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH2_k127_661603_1	1303518.CCALI_02490	6.127e-104	349.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_661603_3	330214.NIDE3403	1.489e-57	209.0	COG2095@1|root,COG2095@2|Bacteria,3J0UZ@40117|Nitrospirae	40117|Nitrospirae	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
YHH2_k127_661603_4	1128912.GMES_4116	1.693e-28	134.0	COG0823@1|root,COG3209@1|root,COG3291@1|root,COG0823@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,1RZ6G@1236|Gammaproteobacteria,46DAC@72275|Alteromonadaceae	1236|Gammaproteobacteria	MU	REJ domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,REJ
YHH2_k127_661603_0	1125863.JAFN01000001_gene613	4.952e-276	859.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH2_k127_6622762_0	1210884.HG799466_gene12933	4.727e-129	456.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
YHH2_k127_6622762_2	794903.OPIT5_27940	5.45e-58	213.0	COG1595@1|root,COG1595@2|Bacteria,46YS4@74201|Verrucomicrobia,3K8W5@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
YHH2_k127_6622762_1	1496688.ER33_13835	7.879e-120	388.0	COG0426@1|root,COG0426@2|Bacteria,1GPET@1117|Cyanobacteria,22SW2@167375|Cyanobium	1117|Cyanobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6622762_3	330214.NIDE4047	1.036e-30	123.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH2_k127_6624903_6	530564.Psta_0874	4.102e-62	219.0	COG0386@1|root,COG0386@2|Bacteria,2IZ7Z@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
YHH2_k127_6624903_9	720554.Clocl_4096	8.116e-13	76.0	COG1699@1|root,COG1699@2|Bacteria,1VA6Y@1239|Firmicutes,24QXE@186801|Clostridia,3WJQX@541000|Ruminococcaceae	186801|Clostridia	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
YHH2_k127_6624903_8	926692.AZYG01000023_gene2601	2.219e-13	72.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,24QPD@186801|Clostridia,3WAY7@53433|Halanaerobiales	186801|Clostridia	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
YHH2_k127_6624903_11	316067.Geob_2304	5.132e-11	72.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K12980	-	-	-	-	ko00000,ko01005	-	-	-	Alginate_exp,OMP_b-brl,Surface_Ag_2
YHH2_k127_6624903_4	562970.Btus_0613	5.499e-101	345.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HBS0@91061|Bacilli,279F0@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH2_k127_6624903_7	511145.b4137	1.164e-23	109.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,1SCFM@1236|Gammaproteobacteria,3XPPZ@561|Escherichia	1236|Gammaproteobacteria	P	Involved in resistance toward heavy metals	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
YHH2_k127_6624903_2	497964.CfE428DRAFT_6615	8.107e-230	725.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
YHH2_k127_6624903_12	1392489.JPOL01000003_gene98	3.963e-07	63.0	COG4644@1|root,COG4644@2|Bacteria,4NQZ0@976|Bacteroidetes,1I8NZ@117743|Flavobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF4158)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
YHH2_k127_6624903_5	497964.CfE428DRAFT_5027	1.673e-89	315.0	COG1520@1|root,COG1520@2|Bacteria,46U9S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_6624903_10	247490.KSU1_C1333	5.362e-12	75.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
YHH2_k127_6624903_0	886293.Sinac_0949	1.291e-282	925.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
YHH2_k127_6624903_1	595460.RRSWK_00676	3.233e-263	867.0	COG1520@1|root,COG3533@1|root,COG1520@2|Bacteria,COG3533@2|Bacteria,2IWVC@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_6624903_3	1396141.BATP01000040_gene2191	7.024e-204	643.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,2IVCR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_662844_3	795797.C497_07204	7.169e-36	143.0	COG1012@1|root,arCOG01252@2157|Archaea,2XT1Y@28890|Euryarchaeota,23SU2@183963|Halobacteria	183963|Halobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
YHH2_k127_662844_0	1267535.KB906767_gene4517	2.838e-87	301.0	COG1454@1|root,COG1454@2|Bacteria	2|Bacteria	C	hydroxyacid-oxoacid transhydrogenase activity	gbd	-	1.1.1.1,1.1.1.61	ko:K00001,ko:K00043,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01644,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
YHH2_k127_662844_1	314230.DSM3645_06659	9.357e-65	235.0	COG4850@1|root,COG4850@2|Bacteria,2IZDS@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
YHH2_k127_662844_2	478741.JAFS01000001_gene1893	9.014e-43	163.0	COG0707@1|root,COG0707@2|Bacteria,46SRU@74201|Verrucomicrobia,37G9Z@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
YHH2_k127_6655811_4	987059.RBXJA2T_14241	1.925e-07	65.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_2,Calx-beta,Laminin_G_3,PA14,VPEP
YHH2_k127_6655811_1	1408433.JHXV01000026_gene3058	8.07e-39	169.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
YHH2_k127_6655811_2	696281.Desru_2763	8.851e-14	86.0	COG1470@1|root,COG3210@1|root,COG3637@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	oprH	-	-	ko:K02014,ko:K13735,ko:K16087,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.14,1.B.14.2	-	-	OMP_b-brl,SLH,fn3
YHH2_k127_6655811_3	443144.GM21_0210	3.75e-13	82.0	2FIN6@1|root,34AE1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6655811_0	573061.Clocel_1966	2.694e-43	177.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH2_k127_6671651_3	589865.DaAHT2_1557	7.445e-22	97.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,42VSU@68525|delta/epsilon subdivisions,2WR9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH2_k127_6671651_0	497964.CfE428DRAFT_5240	1.389e-144	464.0	COG2326@1|root,COG2326@2|Bacteria,46SAH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
YHH2_k127_6671651_1	240016.ABIZ01000001_gene5627	3.854e-68	241.0	COG2755@1|root,COG2755@2|Bacteria,46XD3@74201|Verrucomicrobia,2IVHH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH2_k127_6671651_2	543728.Vapar_4603	2.699e-65	256.0	COG2304@1|root,COG2304@2|Bacteria,1QU09@1224|Proteobacteria,2WGS7@28216|Betaproteobacteria,4AK2H@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM outer membrane adhesin like proteiin	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,VWA_2
YHH2_k127_6736004_3	1396418.BATQ01000140_gene3171	1.86e-25	115.0	COG0322@1|root,COG0322@2|Bacteria	2|Bacteria	L	excinuclease ABC activity	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR
YHH2_k127_6736004_1	583355.Caka_0059	6.903e-52	187.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.83	ko:K20846	-	-	-	-	ko00000,ko01000	-	GH16	-	Big_4,Glyco_hydro_16,RicinB_lectin_2
YHH2_k127_6736004_5	1207076.ALAT01000011_gene1541	0.0003443	44.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,1RPDS@1236|Gammaproteobacteria,1YZVU@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	I	membrane-associated protein	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2,SNARE_assoc
YHH2_k127_6736004_0	497964.CfE428DRAFT_0145	7.748e-112	376.0	COG4826@1|root,COG4826@2|Bacteria,46VTK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	SERine  Proteinase INhibitors	-	-	-	-	-	-	-	-	-	-	-	-	Serpin
YHH2_k127_6736004_4	661478.OP10G_1460	1.366e-16	85.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_6736004_2	329726.AM1_2739	6.44e-47	185.0	COG0457@1|root,COG3063@1|root,COG3271@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,COG3271@2|Bacteria	2|Bacteria	NU	photosynthesis	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	DUF3335,Peptidase_C39_2,Peptidase_C70,TPR_16,TPR_8,VCBS
YHH2_k127_6748116_1	1117108.PAALTS15_29436	3.601e-07	61.0	COG5184@1|root,COG5492@1|root,COG5184@2|Bacteria,COG5492@2|Bacteria,1TQ2K@1239|Firmicutes,4HBG8@91061|Bacilli,26R5R@186822|Paenibacillaceae	91061|Bacilli	N	polysaccharide lyase family 8 domain protein	hylB	GO:0005575,GO:0005576	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Big_2,F5_F8_type_C,FIVAR,Gram_pos_anchor,Lyase_8,Lyase_8_C,Lyase_8_N,YSIRK_signal
YHH2_k127_6748116_0	1235803.C825_03090	9.365e-130	430.0	COG0383@1|root,COG0383@2|Bacteria,4P1Z7@976|Bacteroidetes,2FTJ7@200643|Bacteroidia	976|Bacteroidetes	G	alpha-mannosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_38,Glyco_hydro_38C
YHH2_k127_6749596_0	5888.CAK86303	1.321e-12	81.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
YHH2_k127_675713_1	1121904.ARBP01000009_gene4249	2.177e-147	480.0	COG4948@1|root,COG4948@2|Bacteria,4NI24@976|Bacteroidetes,47N24@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YHH2_k127_675713_3	1121904.ARBP01000009_gene4400	6.158e-99	339.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,47JSH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
YHH2_k127_675713_2	349741.Amuc_1584	5.71e-121	401.0	COG1459@1|root,COG1459@2|Bacteria,46U60@74201|Verrucomicrobia,2IWMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH2_k127_675713_0	240016.ABIZ01000001_gene4226	2.131e-183	585.0	COG3119@1|root,COG3119@2|Bacteria,46TYX@74201|Verrucomicrobia,2IVJJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH2_k127_6786069_3	670292.JH26_08255	2.785e-31	129.0	COG1172@1|root,COG1172@2|Bacteria,1RBVF@1224|Proteobacteria,2U58Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
YHH2_k127_6786069_1	1089551.KE386572_gene1625	1.348e-93	317.0	COG1879@1|root,COG1879@2|Bacteria,1QJ9B@1224|Proteobacteria,2U8ZS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
YHH2_k127_6786069_2	761193.Runsl_3634	2.88e-73	258.0	COG1082@1|root,COG1082@2|Bacteria,4NPBS@976|Bacteroidetes,47Q6G@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_6786069_0	1288494.EBAPG3_18410	0.0	1135.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,37271@32003|Nitrosomonadales	28216|Betaproteobacteria	L	DNA topoisomerase, type IA, central	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
YHH2_k127_6786069_4	485913.Krac_12099	2.55e-29	122.0	COG0486@1|root,COG0486@2|Bacteria,2G647@200795|Chloroflexi	200795|Chloroflexi	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
YHH2_k127_6787182_2	340177.Cag_1409	4.303e-28	125.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH2_k127_6787182_0	340177.Cag_0615	7.888e-63	242.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
YHH2_k127_6787182_1	794903.OPIT5_03265	3.457e-36	145.0	COG1994@1|root,COG1994@2|Bacteria,46X2W@74201|Verrucomicrobia,3K8K3@414999|Opitutae	414999|Opitutae	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6790518_12	1340493.JNIF01000003_gene4476	2.927e-13	74.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	ko:K07004,ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	ASH,CHU_C,DUF11,SGL
YHH2_k127_6790518_9	583355.Caka_0841	1.326e-62	239.0	COG0457@1|root,COG0457@2|Bacteria,46SRS@74201|Verrucomicrobia,3K7VK@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6790518_6	1156937.MFUM_940043	6.656e-79	279.0	COG1235@1|root,COG1235@2|Bacteria,46SRW@74201|Verrucomicrobia,37GEK@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
YHH2_k127_6790518_1	497964.CfE428DRAFT_2490	3.819e-147	484.0	COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
YHH2_k127_6790518_13	497964.CfE428DRAFT_2383	9.634e-13	75.0	2F78F@1|root,33ZPQ@2|Bacteria,46VT2@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6790518_2	452637.Oter_1401	1.645e-143	467.0	COG0205@1|root,COG0205@2|Bacteria,46SFN@74201|Verrucomicrobia,3K7HI@414999|Opitutae	414999|Opitutae	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
YHH2_k127_6790518_3	1000565.METUNv1_01665	7.807e-135	439.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,2KV8P@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rmlB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YHH2_k127_6790518_5	595460.RRSWK_05816	4.754e-89	309.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
YHH2_k127_6790518_4	360910.BAV1244	4.362e-130	421.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2VHA6@28216|Betaproteobacteria,3T6B4@506|Alcaligenaceae	28216|Betaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YHH2_k127_6790518_7	1232410.KI421413_gene654	1.079e-77	269.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,43SAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	SMART AAA ATPase	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
YHH2_k127_6790518_10	1183438.GKIL_2126	9.791e-42	162.0	COG1266@1|root,COG1266@2|Bacteria,1GFE4@1117|Cyanobacteria	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YHH2_k127_6790518_8	1254432.SCE1572_38850	2.131e-73	269.0	COG0564@1|root,COG1092@1|root,COG0564@2|Bacteria,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,42Q87@68525|delta/epsilon subdivisions,2WPIN@28221|Deltaproteobacteria,2Z02J@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PseudoU_synth_2
YHH2_k127_6790518_15	635013.TherJR_0609	0.0008986	51.0	COG0830@1|root,COG0830@2|Bacteria,1V2H0@1239|Firmicutes,24ETM@186801|Clostridia,262PC@186807|Peptococcaceae	186801|Clostridia	J	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
YHH2_k127_6790518_0	278957.ABEA03000006_gene4230	1.036e-247	777.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,3K79T@414999|Opitutae	414999|Opitutae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
YHH2_k127_6832173_1	1210884.HG799469_gene14167	2.214e-151	492.0	COG3356@1|root,COG3356@2|Bacteria,2J1Z6@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6832173_3	666685.R2APBS1_0490	3.807e-21	99.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,1RQNE@1236|Gammaproteobacteria,1X55H@135614|Xanthomonadales	135614|Xanthomonadales	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
YHH2_k127_6832173_2	644968.DFW101_1598	9.159e-78	285.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2M92Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
YHH2_k127_6832173_0	1396141.BATP01000060_gene4727	1.437e-248	810.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
YHH2_k127_6832173_4	1396141.BATP01000060_gene4730	2.312e-11	73.0	COG3210@1|root,COG3291@1|root,COG4733@1|root,COG4870@1|root,COG5279@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4870@2|Bacteria,COG5279@2|Bacteria,46XT0@74201|Verrucomicrobia,2IWHU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_683586_1	1142394.PSMK_04700	3.42e-167	544.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA,BCS1_N
YHH2_k127_683586_3	1121403.AUCV01000010_gene1382	6.58e-60	219.0	COG1116@1|root,COG1116@2|Bacteria,1MWZG@1224|Proteobacteria,43CBE@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	ABC transporter	cysA_3	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
YHH2_k127_683586_5	717785.HYPMC_2340	1.998e-38	157.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TTR3@28211|Alphaproteobacteria,3N7S1@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
YHH2_k127_683586_2	765420.OSCT_3130	2.973e-115	421.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
YHH2_k127_683586_7	83406.HDN1F_30540	2.614e-10	76.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
YHH2_k127_683586_6	382464.ABSI01000013_gene1839	6.185e-26	127.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8
YHH2_k127_683586_4	765420.OSCT_0392	5.409e-54	220.0	COG1345@1|root,COG5184@1|root,COG1345@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,He_PIG,HemolysinCabind,RCC1_2,SWM_repeat
YHH2_k127_683586_0	1123242.JH636434_gene5002	2.324e-210	664.0	COG0033@1|root,COG0033@2|Bacteria,2IYG0@203682|Planctomycetes	203682|Planctomycetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YHH2_k127_6889773_2	435591.BDI_2877	1.055e-57	211.0	COG0363@1|root,COG0363@2|Bacteria,4NPBJ@976|Bacteroidetes,2FNEN@200643|Bacteroidia	976|Bacteroidetes	G	COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase	-	-	3.5.99.6	ko:K02080,ko:K02564	ko00052,ko00520,ko01100,map00052,map00520,map01100	-	R00765,R08365	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
YHH2_k127_6889773_1	886293.Sinac_0920	2.709e-146	476.0	COG0673@1|root,COG0673@2|Bacteria,2IWZW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_6889773_0	497964.CfE428DRAFT_4840	1.763e-164	528.0	COG0606@1|root,COG0606@2|Bacteria,46SAK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH2_k127_6889773_4	1218103.CIN01S_04_01850	2.035e-21	94.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1HXWB@117743|Flavobacteriia,3ZQ2A@59732|Chryseobacterium	976|Bacteroidetes	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH2_k127_6889773_7	1122609.AUGT01000020_gene1045	1.272e-11	72.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_6889773_3	1173024.KI912148_gene2730	3.678e-35	149.0	COG5563@1|root,COG5563@2|Bacteria,1GASM@1117|Cyanobacteria	1117|Cyanobacteria	S	Extracellular repeat protein, HAF family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466
YHH2_k127_6889773_5	1173024.KI912148_gene2732	4.7e-17	94.0	COG5563@1|root,COG5563@2|Bacteria,1GASM@1117|Cyanobacteria	1117|Cyanobacteria	S	Extracellular repeat protein, HAF family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466
YHH2_k127_6889773_6	1396418.BATQ01000185_gene2133	2.107e-13	84.0	COG3203@1|root,COG3420@1|root,COG4782@1|root,COG5184@1|root,COG3203@2|Bacteria,COG3420@2|Bacteria,COG4782@2|Bacteria,COG5184@2|Bacteria,46TZK@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,Pectinesterase
YHH2_k127_6889773_8	1403819.BATR01000027_gene877	1.262e-05	49.0	COG0606@1|root,COG0606@2|Bacteria,46SAK@74201|Verrucomicrobia,2ITTW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH2_k127_690582_2	886293.Sinac_2872	1.102e-23	104.0	COG1446@1|root,COG1446@2|Bacteria,2IZ4V@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2,DUF4440
YHH2_k127_690582_0	1396418.BATQ01000130_gene4880	6.4e-175	557.0	COG3875@1|root,COG3875@2|Bacteria,46TVY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
YHH2_k127_690582_1	455632.SGR_6472	6.852e-74	257.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,417HJ@629295|Streptomyces griseus group	201174|Actinobacteria	C	Aldehyde dehydrogenase family	feaB	-	1.2.1.39,1.2.1.8	ko:K00130,ko:K00146	ko00260,ko00360,ko00643,ko01100,ko01120,map00260,map00360,map00643,map01100,map01120	M00555	R02536,R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH2_k127_69713_1	1396141.BATP01000024_gene782	8.016e-68	244.0	COG3523@1|root,COG3523@2|Bacteria,46VI0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ImcF-related N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ImcF-related_N
YHH2_k127_69713_2	497964.CfE428DRAFT_2854	2.647e-47	178.0	2DXSN@1|root,346BX@2|Bacteria,46W22@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Type VI secretion system protein DotU	-	-	-	-	-	-	-	-	-	-	-	-	DotU
YHH2_k127_69713_0	497964.CfE428DRAFT_2853	9.895e-114	382.0	COG3522@1|root,COG3522@2|Bacteria,46UPG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VasE
YHH2_k127_6980029_1	497964.CfE428DRAFT_4366	2.573e-161	517.0	COG1520@1|root,COG1520@2|Bacteria,46TRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_6980029_0	240016.ABIZ01000001_gene4547	4.443e-174	563.0	COG1262@1|root,COG2010@1|root,COG1262@2|Bacteria,COG2010@2|Bacteria,46UX3@74201|Verrucomicrobia,2ITQQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PSCyt1
YHH2_k127_6980029_2	344747.PM8797T_23639	2.47e-67	235.0	COG1477@1|root,COG1477@2|Bacteria,2IY0F@203682|Planctomycetes	203682|Planctomycetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
YHH2_k127_7017407_9	1210884.HG799465_gene11510	0.0001622	51.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	WD40
YHH2_k127_7017407_7	713587.THITH_05595	1.359e-10	67.0	COG1848@1|root,COG1848@2|Bacteria,1Q9A8@1224|Proteobacteria,1SPBZ@1236|Gammaproteobacteria,1X0SZ@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
YHH2_k127_7017407_1	497964.CfE428DRAFT_2492	2.021e-38	153.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
YHH2_k127_7017407_6	204669.Acid345_4091	1.466e-14	81.0	28NY3@1|root,2ZBVC@2|Bacteria,3Y8CE@57723|Acidobacteria,2JNAC@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7017407_10	886293.Sinac_2760	0.0002039	48.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
YHH2_k127_7017407_0	485913.Krac_9549	5.688e-56	207.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2G7P2@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8,WD40
YHH2_k127_7017407_2	1121468.AUBR01000096_gene781	5.18e-22	101.0	2AII4@1|root,31902@2|Bacteria,1VY3B@1239|Firmicutes,251KQ@186801|Clostridia,42IFA@68295|Thermoanaerobacterales	186801|Clostridia	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7017407_8	1122134.KB893650_gene1298	1.493e-06	56.0	2FBD5@1|root,343IZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7017407_4	1123008.KB905693_gene1189	1.138e-18	95.0	COG4733@1|root,COG4733@2|Bacteria,4NK9Y@976|Bacteroidetes,2FQ1A@200643|Bacteroidia,22YPP@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
YHH2_k127_7039365_1	497964.CfE428DRAFT_4749	3.919e-138	465.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K13598,ko:K13924	ko02020,ko02030,map02020,map02030	M00498,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	ABC_sub_bind,CHASE4,GAF,HAMP,HATPase_c,HDOD,HisKA,PAS,PAS_3,PAS_4,PAS_9
YHH2_k127_7039365_0	452637.Oter_4134	9.295e-205	659.0	COG0784@1|root,COG2204@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia,3K7G0@414999|Opitutae	414999|Opitutae	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
YHH2_k127_7091542_1	215803.DB30_0528	3.246e-85	295.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7091542_2	583355.Caka_0354	1.656e-37	154.0	COG0523@1|root,COG0523@2|Bacteria,46TP3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
YHH2_k127_7091542_0	382464.ABSI01000010_gene3484	2.626e-161	524.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	Thioredoxin_3,URO-D
YHH2_k127_7091542_3	1191523.MROS_1518	4.308e-19	96.0	COG2836@1|root,COG2836@2|Bacteria	2|Bacteria	K	Biogenesis protein	braZ	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2,Ferric_reduct
YHH2_k127_7154425_0	886293.Sinac_3618	2.209e-117	413.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
YHH2_k127_7154425_1	1396141.BATP01000060_gene4727	3.131e-54	209.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
YHH2_k127_7195412_2	1396141.BATP01000005_gene6095	7.747e-31	139.0	COG1196@1|root,COG1196@2|Bacteria,46TP5@74201|Verrucomicrobia,2IWNP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7195412_0	1131269.AQVV01000044_gene1783	3.194e-116	389.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7195412_1	1131269.AQVV01000044_gene1785	1.237e-66	246.0	2FEYA@1|root,346X0@2|Bacteria	1131269.AQVV01000044_gene1785|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7195412_3	1089552.KI911559_gene692	7.191e-25	111.0	COG5350@1|root,COG5350@2|Bacteria,1RB7D@1224|Proteobacteria,2U59N@28211|Alphaproteobacteria,2JT7D@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein tyrosine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
YHH2_k127_7195412_4	1210884.HG799468_gene13803	4.537e-17	81.0	COG4102@1|root,COG4102@2|Bacteria,2IYNP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH2_k127_7238794_2	1433126.BN938_0042	2.838e-34	143.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia,22UKP@171550|Rikenellaceae	976|Bacteroidetes	S	NPCBM/NEW2 domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NPCBM
YHH2_k127_7238794_1	1156937.MFUM_90002	1.056e-186	596.0	COG0034@1|root,COG0034@2|Bacteria,46SSU@74201|Verrucomicrobia,37G3Z@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
YHH2_k127_7238794_0	1341151.ASZU01000001_gene679	5.665e-240	767.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,27B9X@186824|Thermoactinomycetaceae	91061|Bacilli	F	AIR synthase related protein, C-terminal domain	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH2_k127_7238794_3	1396141.BATP01000034_gene4198	2.472e-07	59.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_7239573_0	485913.Krac_4635	1.491e-224	718.0	COG3408@1|root,COG3408@2|Bacteria,2G7KB@200795|Chloroflexi	200795|Chloroflexi	G	PFAM alpha-L-rhamnosidase	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YHH2_k127_7239573_1	215803.DB30_5612	1.594e-74	261.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WMED@28221|Deltaproteobacteria,2YYEU@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
YHH2_k127_7270657_2	521674.Plim_2302	9.573e-71	251.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YHH2_k127_7270657_0	497964.CfE428DRAFT_1084	6.838e-308	963.0	COG1966@1|root,COG1966@2|Bacteria,46SC3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
YHH2_k127_7270657_1	643648.Slip_0720	4.268e-88	298.0	COG0194@1|root,COG0194@2|Bacteria	2|Bacteria	F	guanylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_kin
YHH2_k127_7270657_4	1286171.EAL2_c02640	2.646e-19	99.0	COG5607@1|root,COG5607@2|Bacteria,1U4WY@1239|Firmicutes,2510S@186801|Clostridia	186801|Clostridia	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
YHH2_k127_7270657_3	237368.SCABRO_03698	1.227e-32	132.0	2DQMK@1|root,337MR@2|Bacteria	2|Bacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH2_k127_73151_6	906888.JCM19314_3410	2.202e-51	186.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,3HKWI@363408|Nonlabens	976|Bacteroidetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
YHH2_k127_73151_10	794903.OPIT5_29015	2.371e-12	76.0	COG2165@1|root,COG2165@2|Bacteria,46Y3R@74201|Verrucomicrobia,3K99Z@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
YHH2_k127_73151_3	886293.Sinac_0152	1.761e-90	305.0	COG4221@1|root,COG4221@2|Bacteria,2IXHG@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH2_k127_73151_9	452637.Oter_3848	1.002e-13	76.0	2EPKD@1|root,33H70@2|Bacteria,46WC0@74201|Verrucomicrobia,3K89T@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_73151_7	240015.ACP_2565	7.491e-36	140.0	COG0838@1|root,COG0838@2|Bacteria,3Y8B8@57723|Acidobacteria,2JN67@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YHH2_k127_73151_2	240015.ACP_2566	1.411e-105	347.0	COG0377@1|root,COG0377@2|Bacteria,3Y74G@57723|Acidobacteria,2JKT1@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YHH2_k127_73151_4	1267534.KB906754_gene3779	1.178e-82	280.0	COG0852@1|root,COG0852@2|Bacteria,3Y72R@57723|Acidobacteria,2JM53@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
YHH2_k127_73151_0	1267534.KB906754_gene3778	1.044e-195	617.0	COG0649@1|root,COG0649@2|Bacteria,3Y6MU@57723|Acidobacteria,2JKN7@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
YHH2_k127_73151_5	1267534.KB906754_gene3777	4.236e-72	252.0	COG1143@1|root,COG1143@2|Bacteria,3Y6N6@57723|Acidobacteria,2JKQS@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
YHH2_k127_73151_1	1267534.KB906754_gene3776	1.819e-164	526.0	COG1005@1|root,COG1005@2|Bacteria,3Y6TS@57723|Acidobacteria,2JKJQ@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH2_k127_73151_8	240015.ACP_2571	4.778e-21	96.0	COG0839@1|root,COG0839@2|Bacteria,3Y84Z@57723|Acidobacteria,2JN7E@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YHH2_k127_731785_0	861299.J421_4459	1.697e-286	895.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH2_k127_731785_1	497964.CfE428DRAFT_3455	1.414e-64	235.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
YHH2_k127_731785_2	1156937.MFUM_920008	7.075e-44	169.0	COG1259@1|root,COG1259@2|Bacteria,46SW6@74201|Verrucomicrobia,37GI8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
YHH2_k127_731785_3	1396141.BATP01000035_gene4114	8.112e-35	149.0	COG1466@1|root,COG1466@2|Bacteria,46T5Y@74201|Verrucomicrobia,2ITP3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
YHH2_k127_731785_4	349741.Amuc_1122	1.575e-15	83.0	COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,2IURI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
YHH2_k127_7329228_6	1191523.MROS_0026	4.408e-14	79.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
YHH2_k127_7329228_2	1167006.UWK_01691	1.206e-84	292.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,42NZ8@68525|delta/epsilon subdivisions,2WK0Y@28221|Deltaproteobacteria,2MPFD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258,ko:K07262	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
YHH2_k127_7329228_0	382464.ABSI01000011_gene2896	1.231e-133	439.0	COG0673@1|root,COG0673@2|Bacteria,46UYM@74201|Verrucomicrobia,2IVG2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_7329228_1	204669.Acid345_3213	1.94e-95	321.0	COG0563@1|root,COG0563@2|Bacteria,3Y421@57723|Acidobacteria,2JI14@204432|Acidobacteriia	57723|Acidobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
YHH2_k127_7329228_3	1082933.MEA186_11056	3.528e-82	287.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
YHH2_k127_7329228_5	1337936.IJ00_22680	7.883e-15	89.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,DUF4625,NPCBM_assoc,PEGA
YHH2_k127_7329228_4	272123.Anacy_4407	8.061e-58	230.0	COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria,1GQ7S@1117|Cyanobacteria,1HRXM@1161|Nostocales	1117|Cyanobacteria	Q	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,HemolysinCabind,LVIVD
YHH2_k127_733441_4	497964.CfE428DRAFT_3426	0.0005061	44.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_5
YHH2_k127_733441_0	1168289.AJKI01000012_gene275	6.268e-183	599.0	COG3533@1|root,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes,2FN3P@200643|Bacteroidia,3XJHK@558415|Marinilabiliaceae	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	DUF4986,Glyco_hydro_127
YHH2_k127_733441_3	365528.KB891134_gene3522	2.424e-05	55.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria,4EX0H@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_733441_2	420662.Mpe_A3784	1.816e-06	53.0	COG4118@1|root,COG4118@2|Bacteria,1NH4W@1224|Proteobacteria,2VXSD@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH2_k127_733441_1	1121439.dsat_2620	2.044e-24	109.0	COG4113@1|root,COG4113@2|Bacteria,1N96B@1224|Proteobacteria,42TZ7@68525|delta/epsilon subdivisions,2WR0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH2_k127_7344145_9	1396418.BATQ01000019_gene4975	4.425e-11	67.0	COG0624@1|root,COG0624@2|Bacteria,46SJS@74201|Verrucomicrobia,2ITQ4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
YHH2_k127_7344145_10	269482.Bcep1808_0825	0.0007536	51.0	COG2244@1|root,COG2244@2|Bacteria,1MYM6@1224|Proteobacteria,2VTI8@28216|Betaproteobacteria,1K2UB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	biosynthesis protein	rfbX	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_3
YHH2_k127_7344145_5	391623.TERMP_00885	4.462e-44	171.0	COG0463@1|root,arCOG00895@2157|Archaea,2Y66T@28890|Euryarchaeota,2454F@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH2_k127_7344145_4	926566.Terro_3683	3.367e-60	216.0	COG2152@1|root,COG2152@2|Bacteria,3Y5H3@57723|Acidobacteria,2JM4K@204432|Acidobacteriia	204432|Acidobacteriia	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_7344145_8	240016.ABIZ01000001_gene4454	1.491e-11	72.0	2BJXT@1|root,32EAA@2|Bacteria,46XIQ@74201|Verrucomicrobia,2IW0S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7344145_7	497964.CfE428DRAFT_2011	2.01e-19	99.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
YHH2_k127_7344145_3	1403819.BATR01000092_gene2785	2.146e-72	254.0	COG0761@1|root,COG0761@2|Bacteria,46SYM@74201|Verrucomicrobia,2IWA1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IM	LytB protein	-	-	-	-	-	-	-	-	-	-	-	-	LYTB
YHH2_k127_7344145_1	497964.CfE428DRAFT_4707	3.149e-157	503.0	COG1060@1|root,COG1060@2|Bacteria	2|Bacteria	H	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity	mqnC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188	1.21.98.1,2.5.1.77	ko:K11779,ko:K11780,ko:K11781,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
YHH2_k127_7344145_0	886293.Sinac_4878	4.554e-178	572.0	COG0531@1|root,COG0531@2|Bacteria,2IXT5@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
YHH2_k127_7344145_6	105559.Nwat_2800	1.21e-25	109.0	2E7TI@1|root,3328N@2|Bacteria,1NCCK@1224|Proteobacteria,1SDE1@1236|Gammaproteobacteria,1X113@135613|Chromatiales	135613|Chromatiales	S	TRL-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	TRL
YHH2_k127_7344145_2	237368.SCABRO_03229	4.791e-108	376.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Laminin_G_3,PKD,PPC,Phage-tail_3,Reprolysin_3,fn3
YHH2_k127_7354585_2	1123279.ATUS01000001_gene1925	3.063e-06	59.0	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,1S2UH@1236|Gammaproteobacteria,1J6KU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Phosphate-selective porin O and P	oprP	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
YHH2_k127_7354585_1	525897.Dbac_1089	9.273e-50	184.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,42XWP@68525|delta/epsilon subdivisions,2WSIE@28221|Deltaproteobacteria,2MFM6@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7354585_0	1304885.AUEY01000019_gene1169	1.006e-106	361.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
YHH2_k127_7361217_3	530564.Psta_2520	2.159e-27	113.0	COG2207@1|root,COG3829@1|root,COG2207@2|Bacteria,COG3829@2|Bacteria,2J1W9@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PAS_4
YHH2_k127_7361217_2	595460.RRSWK_04758	1.887e-41	156.0	2E5WH@1|root,32RS6@2|Bacteria	2|Bacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YHH2_k127_7361217_1	485913.Krac_1152	2.988e-67	248.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH2_k127_7361217_4	760011.Spico_0734	5.215e-05	55.0	COG0477@1|root,COG2814@2|Bacteria,2JAP5@203691|Spirochaetes	203691|Spirochaetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08153,ko:K19576	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.10,2.A.1.2.8	-	-	MFS_1
YHH2_k127_7361217_0	306281.AJLK01000118_gene4092	0.0	1191.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1JKQ6@1189|Stigonemataceae	1117|Cyanobacteria	G	Carbohydrate phosphorylase	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
YHH2_k127_7378518_1	1249997.JHZW01000002_gene866	5.648e-16	79.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1HWUY@117743|Flavobacteriia,2PICW@252356|Maribacter	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
YHH2_k127_7378518_4	983545.Glaag_4127	0.0007426	51.0	COG2165@1|root,COG2165@2|Bacteria,1RHHG@1224|Proteobacteria,1S5ZM@1236|Gammaproteobacteria,468C7@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	mshO	-	-	ko:K12285	-	-	-	-	ko00000,ko02044	-	-	-	N_methyl
YHH2_k127_7378518_0	530564.Psta_3667	4.458e-38	160.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
YHH2_k127_7378518_2	1509403.GW12_13890	0.0004039	53.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,3NKVX@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Type IV pilus assembly protein PilM;	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
YHH2_k127_7378518_3	1123242.JH636434_gene3740	0.0006137	50.0	2BBA4@1|root,324SV@2|Bacteria,2IZWF@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7380899_1	1210884.HG799465_gene11865	6.129e-16	80.0	COG0345@1|root,COG0345@2|Bacteria,2IY5U@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
YHH2_k127_7380899_3	446470.Snas_0537	2.705e-05	47.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
YHH2_k127_7380899_2	1248916.ANFY01000009_gene96	1.525e-11	69.0	COG3055@1|root,COG3055@2|Bacteria,1N85X@1224|Proteobacteria	1224|Proteobacteria	M	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7380899_0	497964.CfE428DRAFT_0418	5.542e-88	294.0	COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH2_k127_7392350_2	118173.KB235914_gene906	1.731e-13	74.0	COG4691@1|root,COG4691@2|Bacteria,1G9I8@1117|Cyanobacteria,1HGF7@1150|Oscillatoriales	1117|Cyanobacteria	S	Plasmid stability protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7392350_1	1121271.AUCM01000026_gene1301	1.241e-40	154.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,2UAIV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
YHH2_k127_7392350_0	452637.Oter_1944	3.171e-91	306.0	COG0507@1|root,COG0507@2|Bacteria,46UM3@74201|Verrucomicrobia,3K8WP@414999|Opitutae	414999|Opitutae	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
YHH2_k127_7406414_2	71139.XP_010060990.1	4.433e-24	103.0	COG0313@1|root,2QQ7V@2759|Eukaryota,37MM3@33090|Viridiplantae,3G8SE@35493|Streptophyta	35493|Streptophyta	H	Ribosomal RNA small subunit methyltransferase	-	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YHH2_k127_7406414_1	755732.Fluta_1212	9.847e-42	179.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1I0BV@117743|Flavobacteriia	976|Bacteroidetes	M	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
YHH2_k127_7406414_3	865937.Gilli_1966	1.203e-19	106.0	COG1749@1|root,COG5295@1|root,COG1749@2|Bacteria,COG5295@2|Bacteria,4NTUT@976|Bacteroidetes	976|Bacteroidetes	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4082
YHH2_k127_7406414_0	1396141.BATP01000034_gene4198	2.726e-202	691.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_7432079_0	518766.Rmar_1740	4.546e-112	377.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1FK20@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_7432079_3	497964.CfE428DRAFT_2603	1.681e-23	111.0	COG4700@1|root,COG4700@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	GerE,PLDc_N,TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
YHH2_k127_7432079_2	309807.SRU_2450	4.146e-89	313.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1FIWB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
YHH2_k127_7432079_1	1379698.RBG1_1C00001G0996	6.845e-90	302.0	COG0463@1|root,COG0463@2|Bacteria,2NS3Y@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
YHH2_k127_7451633_1	671143.DAMO_2299	3.711e-79	283.0	COG0771@1|root,COG0771@2|Bacteria,2NP27@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097	Mur_ligase_C,Mur_ligase_M
YHH2_k127_7451633_0	794903.OPIT5_03555	2.309e-101	342.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia,3K7EK@414999|Opitutae	414999|Opitutae	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
YHH2_k127_7451633_2	497964.CfE428DRAFT_2938	5.974e-23	103.0	COG0770@1|root,COG0770@2|Bacteria,46SDF@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH2_k127_7460415_4	452637.Oter_3173	7.063e-31	130.0	2EFI3@1|root,339AJ@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
YHH2_k127_7460415_6	497964.CfE428DRAFT_4380	4.638e-22	106.0	COG1664@1|root,COG1664@2|Bacteria,46WDW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YHH2_k127_7460415_5	1403819.BATR01000162_gene5344	1.62e-27	116.0	COG1664@1|root,COG1664@2|Bacteria,46VS6@74201|Verrucomicrobia,2IUPK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YHH2_k127_7460415_3	452637.Oter_0820	8.962e-77	265.0	COG0012@1|root,COG0012@2|Bacteria	2|Bacteria	J	GTP binding	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YHH2_k127_7460415_0	497964.CfE428DRAFT_6083	6.565e-280	872.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
YHH2_k127_7460415_1	1123508.JH636440_gene2840	1.284e-166	541.0	COG3391@1|root,COG3391@2|Bacteria,2IY6R@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7460415_2	595460.RRSWK_04460	5.32e-100	341.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
YHH2_k127_7472208_1	1396418.BATQ01000117_gene4519	3.834e-75	254.0	COG0031@1|root,COG0031@2|Bacteria,46W12@74201|Verrucomicrobia,2IWMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH2_k127_7472208_0	344747.PM8797T_00347	6.399e-124	407.0	COG1158@1|root,COG1158@2|Bacteria,2IXBX@203682|Planctomycetes	203682|Planctomycetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
YHH2_k127_7472208_2	452637.Oter_1808	1.064e-48	181.0	COG2378@1|root,COG2378@2|Bacteria,46VG3@74201|Verrucomicrobia,3K846@414999|Opitutae	414999|Opitutae	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
YHH2_k127_7479135_7	1430440.MGMSRv2_2789	7.352e-11	75.0	COG2202@1|root,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HWE_HK,PAS,PAS_4,PAS_9
YHH2_k127_7479135_3	909663.KI867150_gene154	2.339e-50	200.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
YHH2_k127_7479135_6	1304875.JAFZ01000001_gene951	3.091e-24	119.0	COG3292@1|root,COG3829@1|root,COG4585@1|root,COG3292@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,3TAJV@508458|Synergistetes	508458|Synergistetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
YHH2_k127_7479135_4	452637.Oter_1551	1.953e-45	169.0	COG2197@1|root,COG2197@2|Bacteria,46SRM@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_7479135_2	644966.Tmar_0895	3.467e-69	248.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
YHH2_k127_7479135_5	583355.Caka_1868	3.072e-39	148.0	COG0695@1|root,COG0695@2|Bacteria,46SXS@74201|Verrucomicrobia,3K871@414999|Opitutae	414999|Opitutae	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
YHH2_k127_7479135_1	278957.ABEA03000040_gene3885	1.587e-84	291.0	COG0414@1|root,COG0414@2|Bacteria,46SRN@74201|Verrucomicrobia,3K7TI@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
YHH2_k127_7479135_0	290397.Adeh_3566	4.68e-202	642.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2YUGG@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH2_k127_7490740_1	1123508.JH636444_gene5364	1.723e-93	308.0	COG1082@1|root,COG1082@2|Bacteria,2IXRD@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
YHH2_k127_7490740_2	1397528.Q671_01165	5.498e-66	230.0	COG2314@1|root,COG2314@2|Bacteria,1RHUU@1224|Proteobacteria,1S694@1236|Gammaproteobacteria,1XPBP@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	TM2
YHH2_k127_7490740_0	497964.CfE428DRAFT_1743	1.706e-255	802.0	COG1166@1|root,COG1166@2|Bacteria,46S4T@74201|Verrucomicrobia	74201|Verrucomicrobia	E	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
YHH2_k127_7490740_3	1303518.CCALI_02288	7.613e-48	186.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
YHH2_k127_7490740_4	866536.Belba_2373	1.659e-21	97.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_7544790_1	1168034.FH5T_03280	2.241e-29	126.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	dppX	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
YHH2_k127_7544790_0	411477.PARMER_04098	1.521e-104	359.0	COG0823@1|root,COG0823@2|Bacteria,4NGH4@976|Bacteroidetes,2FN8G@200643|Bacteroidia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH2_k127_7544790_2	547042.BACCOPRO_00313	2.993e-13	83.0	2DBP6@1|root,2ZA7R@2|Bacteria,4NKM4@976|Bacteroidetes,2FQA8@200643|Bacteroidia,4APXS@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7544790_3	1274374.CBLK010000070_gene1106	0.0008731	44.0	COG0457@1|root,COG0793@1|root,COG0457@2|Bacteria,COG0793@2|Bacteria,1V076@1239|Firmicutes,4HQQT@91061|Bacilli,272BT@186822|Paenibacillaceae	91061|Bacilli	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,TPR_16,TPR_2,TPR_8
YHH2_k127_7548226_0	1128421.JAGA01000001_gene2345	1.464e-73	285.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CARDB,CBM_3,DUF4091,HYR,Kelch_1,MAM,PA14,PKD,Peptidase_M43,Reprolysin_3
YHH2_k127_7548226_1	517722.AEUE01000010_gene532	9.657e-41	177.0	COG3468@1|root,COG4412@1|root,COG3468@2|Bacteria,COG4412@2|Bacteria,1MVQ6@1224|Proteobacteria,2UAUP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	MU	Outer membrane autotransporter	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Calx-beta
YHH2_k127_7574079_6	335543.Sfum_3691	3.694e-45	169.0	COG0705@1|root,COG0705@2|Bacteria,1Q5NI@1224|Proteobacteria,431IG@68525|delta/epsilon subdivisions,2WWXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH2_k127_7574079_0	1121904.ARBP01000005_gene4837	2.03e-129	430.0	COG3356@1|root,COG3356@2|Bacteria,4NH6U@976|Bacteroidetes,47NFZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
YHH2_k127_7574079_2	517418.Ctha_0233	9.628e-122	417.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1FDRS@1090|Chlorobi	1090|Chlorobi	C	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YHH2_k127_7574079_4	517418.Ctha_0234	1.245e-50	186.0	COG1225@1|root,COG1225@2|Bacteria,1FF4E@1090|Chlorobi	1090|Chlorobi	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH2_k127_7574079_3	1122222.AXWR01000014_gene1274	2.681e-63	221.0	COG0041@1|root,COG0041@2|Bacteria,1WJ89@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YHH2_k127_7574079_1	1156937.MFUM_870060	5.263e-129	419.0	COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,37GGN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
YHH2_k127_7574079_7	497964.CfE428DRAFT_1544	4.913e-41	161.0	COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
YHH2_k127_7574079_5	742738.HMPREF9460_00016	1.205e-49	183.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,2686B@186813|unclassified Clostridiales	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
YHH2_k127_7574079_9	1156937.MFUM_230016	2.066e-10	65.0	COG0360@1|root,COG0360@2|Bacteria,46TBG@74201|Verrucomicrobia,37GXZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
YHH2_k127_7574079_8	497964.CfE428DRAFT_1541	4.44e-40	151.0	COG0629@1|root,COG0629@2|Bacteria,46VGA@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YHH2_k127_7605602_3	1123508.JH636440_gene2024	1.438e-12	68.0	28MCY@1|root,2ZAQW@2|Bacteria,2IYAJ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7605602_2	449447.MAE_12430	3.564e-42	179.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04W@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Proprotein convertase P-domain	prcA	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
YHH2_k127_7605602_1	1134912.AJTV01000030_gene2088	7.204e-76	288.0	COG2755@1|root,COG3291@1|root,COG2755@2|Bacteria,COG3291@2|Bacteria,1MYCW@1224|Proteobacteria	1224|Proteobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA
YHH2_k127_7605602_0	1123277.KB893195_gene5580	1.518e-120	405.0	COG2374@1|root,COG3291@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CHU_C,Exo_endo_phos,LTD,PKD
YHH2_k127_7612268_0	452637.Oter_4089	6.489e-197	623.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46TNN@74201|Verrucomicrobia,3K7A5@414999|Opitutae	414999|Opitutae	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH2_k127_7612268_3	909663.KI867150_gene1086	2.191e-75	259.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42N8J@68525|delta/epsilon subdivisions,2WK63@28221|Deltaproteobacteria,2MRGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_7612268_4	909663.KI867150_gene1087	4.69e-65	236.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675,ko:K09684	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,MASE1,PAS,PAS_3,PAS_4,PAS_9,Peripla_BP_3,Response_reg,dCache_2
YHH2_k127_7612268_2	497964.CfE428DRAFT_5373	3.808e-138	449.0	COG0232@1|root,COG0232@2|Bacteria,46UHP@74201|Verrucomicrobia	74201|Verrucomicrobia	F	SMART metal-dependent phosphohydrolase HD region	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
YHH2_k127_7612268_1	1156937.MFUM_920019	1.609e-179	570.0	COG0761@1|root,COG0761@2|Bacteria,46SAR@74201|Verrucomicrobia,37GD1@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	lytB	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
YHH2_k127_7612268_5	697282.Mettu_0399	1.279e-22	101.0	COG3668@1|root,COG3668@2|Bacteria,1N8DJ@1224|Proteobacteria,1SGE5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_7612268_6	99598.Cal7507_3630	2.443e-16	83.0	COG3668@1|root,COG3668@2|Bacteria,1GG7I@1117|Cyanobacteria,1HQ6I@1161|Nostocales	1117|Cyanobacteria	S	PFAM Plasmid stabilisation system protein	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_7614688_5	269797.Mbar_A1468	4.144e-07	53.0	COG0179@1|root,arCOG00235@2157|Archaea,2XU30@28890|Euryarchaeota,2N9DN@224756|Methanomicrobia	224756|Methanomicrobia	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
YHH2_k127_7614688_4	1172188.KB911831_gene4028	1.211e-18	100.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,2GIRE@201174|Actinobacteria,4FGR4@85021|Intrasporangiaceae	201174|Actinobacteria	O	Subtilase family	mycP	-	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
YHH2_k127_7614688_3	1167006.UWK_03049	2.002e-27	122.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,43BH8@68525|delta/epsilon subdivisions,2X6VM@28221|Deltaproteobacteria,2MPIN@213118|Desulfobacterales	28221|Deltaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcsB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
YHH2_k127_7614688_1	349741.Amuc_0091	1.27e-82	286.0	COG0373@1|root,COG0373@2|Bacteria,46SMQ@74201|Verrucomicrobia,2IU0T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Glutamyl-tRNAGlu reductase, N-terminal domain	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,Shikimate_DH
YHH2_k127_7614688_2	1449126.JQKL01000032_gene1243	5.962e-56	208.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,268I3@186813|unclassified Clostridiales	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15760	Porphobil_deam,Porphobil_deamC
YHH2_k127_7614688_0	497964.CfE428DRAFT_0339	2.71e-165	532.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the precorrin methyltransferase family	cysG	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
YHH2_k127_7614808_1	1267535.KB906767_gene808	6.461e-90	304.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_7614808_2	880072.Desac_2064	3.963e-86	311.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
YHH2_k127_7614808_0	1396141.BATP01000060_gene4727	8.083e-118	402.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
YHH2_k127_7632908_4	1304874.JAFY01000005_gene1289	7.089e-07	60.0	COG0457@1|root,COG0457@2|Bacteria,3TBS0@508458|Synergistetes	508458|Synergistetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
YHH2_k127_7632908_0	243090.RB3482	1.442e-160	525.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH2_k127_7632908_2	278957.ABEA03000201_gene4321	1.157e-45	190.0	COG1450@1|root,COG1450@2|Bacteria,46UJF@74201|Verrucomicrobia,3K7CH@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
YHH2_k127_7632908_1	521674.Plim_2872	3.543e-56	205.0	2AU2S@1|root,31JP5@2|Bacteria,2IZEE@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_7632908_3	1047013.AQSP01000101_gene615	2.022e-38	166.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Gp58
YHH2_k127_76679_1	452637.Oter_0497	5.272e-88	295.0	COG0583@1|root,COG0583@2|Bacteria,46SCJ@74201|Verrucomicrobia,3K7FY@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YHH2_k127_76679_4	867903.ThesuDRAFT_00014	6.377e-31	127.0	COG0213@1|root,COG0295@1|root,COG0213@2|Bacteria,COG0295@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,3WCD5@538999|Clostridiales incertae sedis	186801|Clostridia	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
YHH2_k127_76679_3	1430331.EP10_18360	1.113e-69	247.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YHH2_k127_76679_0	1303518.CCALI_00532	5.558e-158	506.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
YHH2_k127_76679_2	404589.Anae109_0137	9.931e-81	283.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales	28221|Deltaproteobacteria	EGP	of the major facilitator superfamily	agmP	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
YHH2_k127_76679_5	278957.ABEA03000095_gene4619	8.86e-12	79.0	2B9GK@1|root,31PUX@2|Bacteria,46YCB@74201|Verrucomicrobia,3K9AR@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7699827_0	1168034.FH5T_17000	7.35e-133	429.0	COG0788@1|root,COG0788@2|Bacteria,4NEGJ@976|Bacteroidetes,2FN3H@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
YHH2_k127_7699827_3	403833.Pmob_0452	4.719e-35	145.0	COG0637@1|root,COG0637@2|Bacteria,2GDJH@200918|Thermotogae	200918|Thermotogae	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH2_k127_7699827_2	497964.CfE428DRAFT_0837	6.509e-47	172.0	COG2947@1|root,COG2947@2|Bacteria,46VWG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
YHH2_k127_7699827_4	1144275.COCOR_07348	1.43e-13	79.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YV9U@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_7699827_5	318996.AXAZ01000008_gene4276	0.000148	51.0	COG5662@1|root,COG5662@2|Bacteria,1MV95@1224|Proteobacteria,2TVRG@28211|Alphaproteobacteria,3JRXS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
YHH2_k127_7699827_1	497964.CfE428DRAFT_0108	4.043e-61	231.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_770697_4	1229780.BN381_10329	3.386e-08	61.0	COG0705@1|root,COG0705@2|Bacteria,2HCGE@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH2_k127_770697_5	497964.CfE428DRAFT_0038	8.698e-08	55.0	28MCY@1|root,2ZAQW@2|Bacteria,46TDW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_770697_0	452637.Oter_4517	1.039e-69	252.0	COG0673@1|root,COG0673@2|Bacteria,46UJR@74201|Verrucomicrobia,3K94Y@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_770697_3	1408422.JHYF01000001_gene3073	8.648e-09	64.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TRPQ@1239|Firmicutes,24BMX@186801|Clostridia,36F15@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,HTH_18,HTH_AraC
YHH2_k127_7713227_1	1396418.BATQ01000117_gene4548	1.6e-74	272.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH2_k127_7713227_2	240016.ABIZ01000001_gene3086	1.518e-55	202.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,2IVMB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7713227_0	886293.Sinac_0918	1.811e-171	550.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
YHH2_k127_7713227_4	459495.SPLC1_S052130	2.048e-13	74.0	COG2931@1|root,COG3266@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG3391@2|Bacteria,1G02E@1117|Cyanobacteria,1H9TQ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,SBBP
YHH2_k127_7713227_3	1304880.JAGB01000002_gene2153	1.734e-21	105.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_7724722_0	290397.Adeh_2962	7.032e-282	893.0	COG0574@1|root,COG0574@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2Z1W9@29|Myxococcales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
YHH2_k127_7724722_1	406327.Mevan_1556	3.949e-226	707.0	COG0334@1|root,arCOG01352@2157|Archaea,2XU0F@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YHH2_k127_7724722_3	497964.CfE428DRAFT_4660	1.067e-169	542.0	COG1520@1|root,COG1520@2|Bacteria,46TSY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_7724722_2	357808.RoseRS_2735	1.605e-219	704.0	COG3408@1|root,COG3408@2|Bacteria,2G7KB@200795|Chloroflexi,376HX@32061|Chloroflexia	32061|Chloroflexia	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YHH2_k127_7733056_0	1192034.CAP_4867	8.817e-22	109.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,2YU62@29|Myxococcales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
YHH2_k127_7733056_1	497964.CfE428DRAFT_0051	1.419e-17	97.0	COG0760@1|root,COG0760@2|Bacteria,46T1I@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PPIC-type PPIASE domain	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
YHH2_k127_7740992_6	1121405.dsmv_0281	4.664e-12	71.0	COG0457@1|root,COG0457@2|Bacteria,1R4UV@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7740992_3	382464.ABSI01000007_gene4096	1.293e-29	132.0	2E1EI@1|root,32WTG@2|Bacteria,46T04@74201|Verrucomicrobia,2IUNI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7740992_4	1385935.N836_03385	7.538e-22	105.0	COG4974@1|root,COG4974@2|Bacteria,1G7AU@1117|Cyanobacteria,1HHKG@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
YHH2_k127_7740992_5	56780.SYN_02999	4.095e-17	85.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2MRJM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YHH2_k127_7740992_1	497964.CfE428DRAFT_2492	2.414e-58	220.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
YHH2_k127_7740992_0	452637.Oter_1311	1.066e-67	244.0	COG2454@1|root,COG2454@2|Bacteria,46W2F@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7740992_2	1121920.AUAU01000009_gene1881	3.975e-42	178.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
YHH2_k127_7740992_7	497964.CfE428DRAFT_6157	8.136e-09	69.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG4934@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	CHU_C,DUF11,Pro-kuma_activ,SdrD_B
YHH2_k127_7783269_2	497964.CfE428DRAFT_0139	7.09e-145	464.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_7783269_5	1054213.HMPREF9946_04583	1.743e-56	205.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TTNG@28211|Alphaproteobacteria,2JRZ6@204441|Rhodospirillales	204441|Rhodospirillales	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH2_k127_7783269_6	1048983.EL17_22635	2.905e-32	130.0	COG2755@1|root,COG2755@2|Bacteria,4NQAK@976|Bacteroidetes,47QQ7@768503|Cytophagia	976|Bacteroidetes	E	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
YHH2_k127_7783269_0	402881.Plav_3064	3.873e-223	709.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,1JN48@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Adenylylsulphate kinase	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
YHH2_k127_7783269_3	1110502.TMO_0686	3.314e-123	399.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2TT2D@28211|Alphaproteobacteria,2JQKR@204441|Rhodospirillales	204441|Rhodospirillales	EH	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YHH2_k127_7783269_4	867903.ThesuDRAFT_00526	5.842e-66	233.0	COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,24B4B@186801|Clostridia	186801|Clostridia	C	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YHH2_k127_7783269_1	452637.Oter_2432	2.503e-204	649.0	COG0155@1|root,COG0155@2|Bacteria,46U85@74201|Verrucomicrobia,3K77C@414999|Opitutae	414999|Opitutae	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
YHH2_k127_7796320_6	1225184.ALXE01000058_gene3374	5.309e-17	83.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,3VZC6@53335|Pantoea	1236|Gammaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830	Aminotran_1_2
YHH2_k127_7796320_3	883.DvMF_1002	2.698e-126	425.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2MA1I@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
YHH2_k127_7796320_5	1121090.KB894691_gene2592	4.459e-33	133.0	COG0454@1|root,COG0456@2|Bacteria,1VC1N@1239|Firmicutes,4HJT0@91061|Bacilli,1ZGZD@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
YHH2_k127_7796320_0	344747.PM8797T_10559	6.728e-196	617.0	COG0156@1|root,COG0156@2|Bacteria,2IX0H@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_7796320_2	1396141.BATP01000004_gene5874	1.321e-143	471.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Glyco_hydro_98C,Glyco_hydro_98M,NPCBM,Peptidase_M16,Peptidase_M16_C
YHH2_k127_7796320_1	344747.PM8797T_10564	5.036e-189	597.0	COG1063@1|root,COG1063@2|Bacteria,2IX2U@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH2_k127_7796320_4	344747.PM8797T_10569	7.797e-81	276.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,2IZAY@203682|Planctomycetes	203682|Planctomycetes	K	Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
YHH2_k127_7833542_2	1463934.JOCF01000124_gene7299	1.757e-45	177.0	COG1572@1|root,COG3669@1|root,COG1572@2|Bacteria,COG3669@2|Bacteria,2I650@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
YHH2_k127_7833542_3	497964.CfE428DRAFT_1920	1.876e-20	107.0	COG2010@1|root,COG2010@2|Bacteria,46V0R@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
YHH2_k127_7833542_1	1227453.C444_06346	6.99e-67	254.0	COG1621@1|root,arCOG08134@2157|Archaea,2XUXA@28890|Euryarchaeota,23UA6@183963|Halobacteria	183963|Halobacteria	G	COG1621 Beta-fructosidases (levanase invertase)	scrB	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	DUF4960,Glyco_hydro_32C,Glyco_hydro_32N
YHH2_k127_7833542_0	240292.Ava_0582	9.843e-86	318.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria	1117|Cyanobacteria	DZ	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
YHH2_k127_7838611_3	743718.Isova_1728	4.275e-12	70.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4F3PY@85017|Promicromonosporaceae	201174|Actinobacteria	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
YHH2_k127_7838611_1	1245475.ANAE01000095_gene4329	2.054e-67	248.0	COG2160@1|root,COG2160@2|Bacteria,2GJNB@201174|Actinobacteria,4EGQ7@85012|Streptosporangiales	201174|Actinobacteria	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
YHH2_k127_7838611_2	1122917.KB899666_gene3398	2.068e-42	173.0	COG4992@1|root,COG4992@2|Bacteria,1VSE7@1239|Firmicutes	1239|Firmicutes	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
YHH2_k127_7838611_0	471854.Dfer_5253	7.252e-125	419.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,47TMC@768503|Cytophagia	976|Bacteroidetes	S	Sodium:solute symporter family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH2_k127_7850987_0	1122603.ATVI01000006_gene55	2.352e-286	895.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,1X478@135614|Xanthomonadales	135614|Xanthomonadales	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
YHH2_k127_7850987_1	575540.Isop_0616	1.089e-70	254.0	COG0526@1|root,COG0526@2|Bacteria,2J06Z@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
YHH2_k127_7850987_2	1122917.KB899677_gene22	1.108e-10	69.0	COG1409@1|root,COG3211@1|root,COG3250@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,COG3250@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
YHH2_k127_7870180_2	906968.Trebr_0168	9.652e-16	92.0	COG0745@1|root,COG0745@2|Bacteria,2J7CK@203691|Spirochaetes	203691|Spirochaetes	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07657,ko:K18941	ko02020,map02020	M00434,M00716,M00717	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_7870180_0	517418.Ctha_2457	1.578e-38	147.0	COG0745@1|root,COG0745@2|Bacteria,1FF6Q@1090|Chlorobi	1090|Chlorobi	T	cheY-homologous receiver domain	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
YHH2_k127_7870180_3	394221.Mmar10_0659	3.58e-13	78.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,2U59Y@28211|Alphaproteobacteria,43YBI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	NT	Two component signalling adaptor domain	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
YHH2_k127_7876164_6	1267534.KB906758_gene2345	2.071e-24	117.0	COG2234@1|root,COG2234@2|Bacteria,3Y80U@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YHH2_k127_7876164_2	391735.Veis_3487	8.145e-66	241.0	arCOG14100@1|root,2Z924@2|Bacteria,1PWEX@1224|Proteobacteria,2VW5B@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
YHH2_k127_7876164_1	1341181.FLJC2902T_21090	1.581e-66	261.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4P772@976|Bacteroidetes,1IBXR@117743|Flavobacteriia,2NWQB@237|Flavobacterium	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SprB
YHH2_k127_7876164_3	1123508.JH636443_gene5001	3.034e-61	243.0	COG1404@1|root,COG2931@1|root,COG3210@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,2J2J4@203682|Planctomycetes	203682|Planctomycetes	OU	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
YHH2_k127_7876164_5	251221.35213566	5.614e-36	160.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7876164_0	1123242.JH636437_gene6142	7.712e-83	284.0	COG1082@1|root,COG1082@2|Bacteria,2IXNX@203682|Planctomycetes	203682|Planctomycetes	G	COG1082 Sugar phosphate	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
YHH2_k127_7886510_3	497964.CfE428DRAFT_1022	8.368e-43	164.0	COG0583@1|root,COG0583@2|Bacteria,46V15@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YHH2_k127_7886510_1	518766.Rmar_1842	1.577e-162	527.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1FJQB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	MFS/sugar transport protein	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
YHH2_k127_7886510_5	1449063.JMLS01000031_gene4732	0.0005063	50.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,4HDV0@91061|Bacilli,27243@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl hydrolases family 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
YHH2_k127_7886510_4	234267.Acid_7434	5.5e-33	136.0	2DPU7@1|root,333E3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7886510_0	1396418.BATQ01000157_gene2423	2.315e-214	683.0	COG1271@1|root,COG1271@2|Bacteria,46UI0@74201|Verrucomicrobia,2IU3N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
YHH2_k127_7886510_2	1396418.BATQ01000157_gene2422	2.958e-159	517.0	COG1294@1|root,COG1294@2|Bacteria,46U7S@74201|Verrucomicrobia,2IUU8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
YHH2_k127_7908363_0	452637.Oter_0886	9.363e-137	445.0	COG0468@1|root,COG0468@2|Bacteria,46SIZ@74201|Verrucomicrobia,3K737@414999|Opitutae	414999|Opitutae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
YHH2_k127_7908363_2	1173020.Cha6605_4216	2.705e-66	239.0	COG1043@1|root,COG1043@2|Bacteria,1G3IU@1117|Cyanobacteria	1117|Cyanobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
YHH2_k127_7908363_3	1499968.TCA2_5773	4.904e-55	202.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,26S1K@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
YHH2_k127_7908363_1	1396141.BATP01000003_gene4934	1.579e-112	405.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
YHH2_k127_7912217_2	497964.CfE428DRAFT_4748	2.349e-102	338.0	COG1208@1|root,COG1208@2|Bacteria,46V3X@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YHH2_k127_7912217_0	580331.Thit_2022	2.341e-163	534.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
YHH2_k127_7912217_1	497964.CfE428DRAFT_5490	2.284e-122	401.0	COG0524@1|root,COG0524@2|Bacteria,46SCP@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH2_k127_7912217_3	497964.CfE428DRAFT_0438	2.658e-13	76.0	COG1520@1|root,COG1572@1|root,COG3227@1|root,COG3391@1|root,COG4782@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,COG3391@2|Bacteria,COG4782@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	DUF900,FTP,Peptidase_M36
YHH2_k127_7926519_4	497964.CfE428DRAFT_0022	6.102e-82	276.0	COG0217@1|root,COG0217@2|Bacteria,46SMV@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
YHH2_k127_7926519_1	1403819.BATR01000134_gene4788	1.357e-124	409.0	COG0079@1|root,COG0079@2|Bacteria,46SFP@74201|Verrucomicrobia,2ITIN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_7926519_2	497964.CfE428DRAFT_4938	1.117e-119	396.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	DRTGG domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
YHH2_k127_7926519_3	497964.CfE428DRAFT_4937	1.543e-116	386.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM phosphate acetyl butaryl transferase	-	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
YHH2_k127_7926519_0	1191523.MROS_0859	0.0	1169.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YHH2_k127_7926519_5	1210884.HG799462_gene7872	1.109e-55	203.0	COG0095@1|root,COG0095@2|Bacteria,2J0D8@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YHH2_k127_7926519_6	240016.ABIZ01000001_gene2019	2.51e-43	174.0	COG0681@1|root,COG0681@2|Bacteria,46SR0@74201|Verrucomicrobia,2IU66@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YHH2_k127_7926519_7	1403819.BATR01000098_gene3262	1.539e-40	151.0	COG0481@1|root,COG0481@2|Bacteria,46SA7@74201|Verrucomicrobia,2IU2I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YHH2_k127_7943448_0	1396141.BATP01000034_gene4199	2.116e-121	412.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Collagen,F5_F8_type_C,FIVAR,Glyco_hydro_43,Laminin_G_3,Metallophos
YHH2_k127_7943448_1	234267.Acid_5864	8.273e-56	214.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_7943448_4	234267.Acid_6615	1.446e-19	100.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7943448_2	867903.ThesuDRAFT_00190	2.672e-42	173.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3WCJP@538999|Clostridiales incertae sedis	186801|Clostridia	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
YHH2_k127_7943448_3	1499689.CCNN01000009_gene2763	1.171e-21	97.0	COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,24ES6@186801|Clostridia,36EBE@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
YHH2_k127_7980978_3	1403819.BATR01000022_gene762	1.606e-30	125.0	COG0838@1|root,COG0838@2|Bacteria,46T33@74201|Verrucomicrobia,2IUK0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YHH2_k127_7980978_2	497964.CfE428DRAFT_6361	4.226e-38	150.0	2FICZ@1|root,34A57@2|Bacteria,46W7Z@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7980978_1	497964.CfE428DRAFT_6362	1.969e-98	330.0	COG1146@1|root,COG1146@2|Bacteria,46TI2@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7980978_0	1396418.BATQ01000157_gene2420	1.527e-175	560.0	COG0535@1|root,COG0535@2|Bacteria,46TZN@74201|Verrucomicrobia	74201|Verrucomicrobia	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
YHH2_k127_7986215_0	794903.OPIT5_08365	1.026e-07	58.0	2A628@1|root,30UUM@2|Bacteria,46YPR@74201|Verrucomicrobia,3K9YA@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_7986215_1	1207063.P24_11947	9.782e-05	53.0	28IAN@1|root,2Z8D8@2|Bacteria,1NJD6@1224|Proteobacteria,2U3QV@28211|Alphaproteobacteria,2JYIM@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF4055)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4055
YHH2_k127_8019606_9	1499967.BAYZ01000044_gene2999	0.0004192	48.0	2EPAA@1|root,33GX1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8019606_6	497964.CfE428DRAFT_5946	3.611e-38	149.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_8019606_8	1379270.AUXF01000006_gene66	1.557e-08	57.0	COG0828@1|root,COG0828@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
YHH2_k127_8019606_3	497964.CfE428DRAFT_1667	1.645e-79	275.0	COG1082@1|root,COG1082@2|Bacteria,46SWH@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_8019606_7	478741.JAFS01000002_gene473	5.736e-32	139.0	COG0392@1|root,COG0392@2|Bacteria,46T31@74201|Verrucomicrobia,37GPN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YHH2_k127_8019606_1	382464.ABSI01000010_gene3676	1.087e-156	509.0	COG2204@1|root,COG2204@2|Bacteria,46SDB@74201|Verrucomicrobia,2IU0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
YHH2_k127_8019606_4	497964.CfE428DRAFT_5735	4.716e-48	192.0	COG4796@1|root,COG4796@2|Bacteria,46STU@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin
YHH2_k127_8019606_5	497964.CfE428DRAFT_2725	9.081e-40	162.0	COG4972@1|root,COG4972@2|Bacteria	2|Bacteria	NU	Pilus assembly protein	pilM	-	-	ko:K02461,ko:K02662	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	PilM_2
YHH2_k127_8019606_2	429009.Adeg_0968	8.52e-99	336.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,42F3J@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
YHH2_k127_8019606_0	452637.Oter_2055	9.432e-184	581.0	COG4656@1|root,COG4656@2|Bacteria,46W83@74201|Verrucomicrobia	74201|Verrucomicrobia	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
YHH2_k127_803923_7	497964.CfE428DRAFT_5370	3.296e-91	304.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YHH2_k127_803923_6	497964.CfE428DRAFT_0539	1.547e-93	310.0	COG1403@1|root,COG1403@2|Bacteria,46SMP@74201|Verrucomicrobia	74201|Verrucomicrobia	L	HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH_5
YHH2_k127_803923_14	497964.CfE428DRAFT_2957	3.469e-32	131.0	COG2026@1|root,COG2026@2|Bacteria,46T5H@74201|Verrucomicrobia	74201|Verrucomicrobia	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YHH2_k127_803923_9	1444310.JANV01000138_gene1990	3.666e-59	236.0	COG1361@1|root,COG3209@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli,1ZRBP@1386|Bacillus	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YHH2_k127_803923_16	497964.CfE428DRAFT_2131	3.722e-24	111.0	29NX7@1|root,309VB@2|Bacteria,46WPG@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_803923_15	404589.Anae109_2317	7.154e-26	113.0	COG0622@1|root,COG0622@2|Bacteria,1N8BH@1224|Proteobacteria,43BGF@68525|delta/epsilon subdivisions,2X6UQ@28221|Deltaproteobacteria,2Z0CD@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
YHH2_k127_803923_1	1156937.MFUM_790015	8.968e-169	546.0	COG0322@1|root,COG0322@2|Bacteria,46SAJ@74201|Verrucomicrobia,37GFU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
YHH2_k127_803923_11	497964.CfE428DRAFT_0221	2.27e-39	154.0	2EKW2@1|root,33EJK@2|Bacteria,46VZV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_803923_10	1123070.KB899254_gene1231	1.749e-58	210.0	COG0571@1|root,COG0571@2|Bacteria,46T3X@74201|Verrucomicrobia,2IU7S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YHH2_k127_803923_4	1123070.KB899250_gene607	5.27e-135	448.0	COG0168@1|root,COG0168@2|Bacteria,46UGP@74201|Verrucomicrobia,2IVEG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
YHH2_k127_803923_3	1123070.KB899250_gene608	1.722e-148	483.0	COG0569@1|root,COG0569@2|Bacteria,46W0A@74201|Verrucomicrobia,2IUXU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
YHH2_k127_803923_5	497964.CfE428DRAFT_2397	1.835e-106	356.0	COG1858@1|root,COG1858@2|Bacteria,46SJU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Di-haem cytochrome c peroxidase	mauG	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
YHH2_k127_803923_19	1278073.MYSTI_06366	6.774e-06	55.0	COG4968@1|root,COG4968@2|Bacteria,1QXV9@1224|Proteobacteria,42VR9@68525|delta/epsilon subdivisions,2WRJV@28221|Deltaproteobacteria,2YW4P@29|Myxococcales	28221|Deltaproteobacteria	NU	Type IV pilin PilA	pilA	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_PilA
YHH2_k127_803923_13	1121924.ATWH01000017_gene3159	1.239e-32	147.0	COG3408@1|root,COG3408@2|Bacteria,2GYU2@201174|Actinobacteria,4FR4D@85023|Microbacteriaceae	201174|Actinobacteria	G	Glycosyl-hydrolase family 116, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DUF608
YHH2_k127_803923_20	408672.NBCG_02014	0.0004933	53.0	COG3325@1|root,COG3325@2|Bacteria,2GNWP@201174|Actinobacteria,4DQ7N@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyl hydrolases family 18	-	-	3.2.1.96	ko:K01227	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_18
YHH2_k127_803923_8	926562.Oweho_0246	1.44e-59	233.0	COG3211@1|root,COG3211@2|Bacteria,4NZ53@976|Bacteroidetes,1IN2H@117743|Flavobacteriia,2PC64@246874|Cryomorphaceae	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
YHH2_k127_803923_18	401473.BDP_1155	6.163e-12	71.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4D0R3@85004|Bifidobacteriales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	garA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
YHH2_k127_803923_2	497964.CfE428DRAFT_1009	3.627e-165	531.0	COG0247@1|root,COG0247@2|Bacteria,46SAS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_17,Fer4_8
YHH2_k127_803923_0	497964.CfE428DRAFT_1010	1.112e-199	631.0	COG0277@1|root,COG0277@2|Bacteria,46S85@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YHH2_k127_803923_12	1265502.KB905934_gene3233	2.006e-36	143.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria,4AFSH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
YHH2_k127_803923_17	304371.MCP_0432	1.128e-12	70.0	COG0433@1|root,arCOG09167@1|root,arCOG00280@2157|Archaea,arCOG00286@2157|Archaea,arCOG09167@2157|Archaea	2157|Archaea	P	protein kinase activity	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
YHH2_k127_8040052_1	1396141.BATP01000034_gene4198	4.581e-59	231.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_8040052_2	1250005.PHEL85_0454	2.971e-15	90.0	COG1404@1|root,COG2312@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2312@2|Bacteria,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,3VX3A@52959|Polaribacter	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
YHH2_k127_8040052_0	344747.PM8797T_26770	1.771e-76	267.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2IZV4@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
YHH2_k127_8062024_3	517418.Ctha_0772	2.976e-27	117.0	COG2839@1|root,COG2839@2|Bacteria,1FE53@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
YHH2_k127_8062024_1	411470.RUMGNA_01908	6.041e-79	274.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3XYRA@572511|Blautia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH2_k127_8062024_2	794903.OPIT5_05580	1.99e-30	126.0	COG0597@1|root,COG0597@2|Bacteria,46TCC@74201|Verrucomicrobia,3K87P@414999|Opitutae	414999|Opitutae	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
YHH2_k127_8062024_0	1163408.UU9_00100	1.458e-144	471.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1X37F@135614|Xanthomonadales	135614|Xanthomonadales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
YHH2_k127_8062024_4	1403819.BATR01000177_gene5955	7.326e-13	72.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,2IUMH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
YHH2_k127_8084317_8	42256.RradSPS_1127	2.143e-39	156.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	-	-	-	-	-	-	-	-	-	-	CbiX
YHH2_k127_8084317_1	794903.OPIT5_28885	4.358e-108	360.0	COG0489@1|root,COG0489@2|Bacteria,46SAV@74201|Verrucomicrobia,3K75Q@414999|Opitutae	414999|Opitutae	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
YHH2_k127_8084317_4	504832.OCAR_6526	2.84e-53	202.0	COG3391@1|root,COG3391@2|Bacteria,1R3YF@1224|Proteobacteria,2TUFI@28211|Alphaproteobacteria,3JWRW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
YHH2_k127_8084317_5	1198232.CYCME_0689	2.381e-52	198.0	COG0515@1|root,COG0515@2|Bacteria,1QU0D@1224|Proteobacteria,1T58D@1236|Gammaproteobacteria,462EW@72273|Thiotrichales	72273|Thiotrichales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
YHH2_k127_8084317_2	1316927.ATKI01000058_gene1797	1.344e-68	240.0	COG0500@1|root,COG0500@2|Bacteria,1NIZX@1224|Proteobacteria,1T2CR@1236|Gammaproteobacteria,1YNHD@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH2_k127_8084317_0	530564.Psta_4258	5.344e-205	649.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH2_k127_8084317_7	243365.CV_1591	1.5e-45	175.0	COG1011@1|root,COG1011@2|Bacteria,1RHAB@1224|Proteobacteria,2VYJP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	IA, variant 3	-	-	3.1.3.10,3.8.1.2	ko:K01560,ko:K20866	ko00010,ko00361,ko00625,ko01100,ko01120,map00010,map00361,map00625,map01100,map01120	-	R00947,R05287	RC00078,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH2_k127_8084317_6	1123023.JIAI01000003_gene2736	5.673e-48	184.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
YHH2_k127_8084317_10	1209072.ALBT01000061_gene1006	5.028e-27	121.0	2DC00@1|root,2ZC4V@2|Bacteria,1RBPR@1224|Proteobacteria,1S2KT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8084317_9	314230.DSM3645_18556	3.898e-33	147.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	BNR,BNR_2
YHH2_k127_8084317_3	1210884.HG799463_gene9547	5.328e-61	233.0	COG1073@1|root,COG1073@2|Bacteria,2J53C@203682|Planctomycetes	203682|Planctomycetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8090375_3	357808.RoseRS_1787	3.804e-25	105.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8090375_2	643473.KB235930_gene1236	1.433e-27	113.0	COG1724@1|root,COG1724@2|Bacteria,1G9SX@1117|Cyanobacteria,1HPVQ@1161|Nostocales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH2_k127_8090375_0	1396141.BATP01000042_gene1907	8.298e-201	635.0	COG3391@1|root,COG3391@2|Bacteria,46WEM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
YHH2_k127_8090375_1	1396141.BATP01000042_gene1906	7.71e-50	185.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
YHH2_k127_8090375_4	314278.NB231_03220	4.209e-07	55.0	COG3021@1|root,COG3021@2|Bacteria,1MWFK@1224|Proteobacteria,1RPPZ@1236|Gammaproteobacteria,1X0D4@135613|Chromatiales	135613|Chromatiales	V	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH2_k127_8111048_0	1396141.BATP01000060_gene4727	5.5e-260	845.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
YHH2_k127_8111048_4	584708.Apau_0390	1.171e-11	78.0	COG2206@1|root,COG2206@2|Bacteria,3TARC@508458|Synergistetes	508458|Synergistetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HD
YHH2_k127_8111048_2	497964.CfE428DRAFT_0066	1.336e-73	275.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
YHH2_k127_8111048_3	497964.CfE428DRAFT_0064	7.785e-48	178.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
YHH2_k127_8111048_1	1123276.KB893270_gene4720	6.393e-201	635.0	COG0673@1|root,COG0673@2|Bacteria,4NHDZ@976|Bacteroidetes,47KJR@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_8140648_0	583355.Caka_0792	6.926e-158	509.0	COG0673@1|root,COG0673@2|Bacteria,46UJR@74201|Verrucomicrobia,3K94Y@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_8140648_4	990285.RGCCGE502_20990	2.487e-42	163.0	COG2215@1|root,COG2215@2|Bacteria	2|Bacteria	O	Belongs to the NiCoT transporter (TC 2.A.52) family	ureH	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	DsbD_2,NicO
YHH2_k127_8140648_1	497964.CfE428DRAFT_2568	1.279e-93	316.0	COG2220@1|root,COG2220@2|Bacteria,46UIR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
YHH2_k127_8140648_3	452637.Oter_4038	2.245e-51	189.0	COG0663@1|root,COG0663@2|Bacteria,46V13@74201|Verrucomicrobia,3K82W@414999|Opitutae	414999|Opitutae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YHH2_k127_8140648_2	562743.JH976435_gene2922	3.035e-81	277.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
YHH2_k127_8149244_6	794903.OPIT5_24930	3.9e-61	223.0	COG1191@1|root,COG1191@2|Bacteria,46TPW@74201|Verrucomicrobia,3K7F7@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH2_k127_8149244_8	452637.Oter_0392	5.092e-12	72.0	2FIUS@1|root,34AK6@2|Bacteria,46WE9@74201|Verrucomicrobia,3K8CJ@414999|Opitutae	414999|Opitutae	S	FlgN protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
YHH2_k127_8149244_7	344747.PM8797T_06105	3.366e-12	69.0	COG1551@1|root,COG1551@2|Bacteria,2J0QX@203682|Planctomycetes	203682|Planctomycetes	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	-	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
YHH2_k127_8149244_5	1131269.AQVV01000001_gene1323	1.757e-73	262.0	2DRTQ@1|root,32URN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8149244_3	497964.CfE428DRAFT_5470	1.037e-107	366.0	COG2204@1|root,COG2204@2|Bacteria,46VVS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH2_k127_8149244_1	497964.CfE428DRAFT_5468	3.852e-180	588.0	COG5000@1|root,COG5000@2|Bacteria,46THS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YHH2_k127_8149244_4	382464.ABSI01000020_gene123	4.68e-106	358.0	COG3437@1|root,COG3437@2|Bacteria,46Z3C@74201|Verrucomicrobia,2IUIF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
YHH2_k127_8149244_0	382464.ABSI01000020_gene122	8.785e-218	708.0	COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,46TS1@74201|Verrucomicrobia,2ITZM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_8149244_2	382464.ABSI01000020_gene121	2.623e-109	364.0	COG0500@1|root,COG0500@2|Bacteria,46YTR@74201|Verrucomicrobia,2IU3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Response_reg
YHH2_k127_8194281_6	1254432.SCE1572_08440	6.677e-28	115.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42NP2@68525|delta/epsilon subdivisions,2WIY2@28221|Deltaproteobacteria,2YUJC@29|Myxococcales	28221|Deltaproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
YHH2_k127_8194281_3	1286106.MPL1_00897	2.198e-57	208.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,462Q4@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH2_k127_8194281_4	1109445.AGSX01000067_gene1344	1.365e-49	188.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1Z1PM@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355	Ubie_methyltran
YHH2_k127_8194281_0	452637.Oter_1491	7.314e-115	383.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH2_k127_8194281_1	452637.Oter_1490	5.79e-95	314.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
YHH2_k127_8194281_2	497964.CfE428DRAFT_4932	1.212e-67	233.0	COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YHH2_k127_8239019_2	1156937.MFUM_1020128	7.621e-120	400.0	COG1132@1|root,COG1132@2|Bacteria,46S6K@74201|Verrucomicrobia,37GCJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
YHH2_k127_8239019_1	497964.CfE428DRAFT_3562	1.808e-132	433.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH2_k127_8239019_0	497964.CfE428DRAFT_2599	5.103e-152	498.0	COG2204@1|root,COG2204@2|Bacteria,46SDB@74201|Verrucomicrobia	74201|Verrucomicrobia	T	sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH2_k127_8239019_3	886293.Sinac_2242	2.624e-89	313.0	COG1167@1|root,COG1167@2|Bacteria,2IY9J@203682|Planctomycetes	203682|Planctomycetes	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
YHH2_k127_8239513_0	1379698.RBG1_1C00001G0984	3.85e-39	161.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
YHH2_k127_8239513_1	1033806.HTIA_1703	2.577e-11	79.0	COG2730@1|root,arCOG09007@2157|Archaea,2XWUS@28890|Euryarchaeota,23V8X@183963|Halobacteria	183963|Halobacteria	G	Carbohydrate binding module (family 6)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_11,Glyco_hydro_16,PKD
YHH2_k127_8239902_1	686340.Metal_3113	9.464e-86	318.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,1S0A9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
YHH2_k127_8239902_0	313612.L8106_20298	2.836e-118	387.0	COG0294@1|root,COG0294@2|Bacteria,1G4A8@1117|Cyanobacteria,1HA6P@1150|Oscillatoriales	1117|Cyanobacteria	H	synthase	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_bind
YHH2_k127_8239902_2	497964.CfE428DRAFT_3494	1.384e-56	207.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	omcN	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,GSu_C4xC__C2xCH,Paired_CXXCH_1,UVR
YHH2_k127_8239902_3	1340493.JNIF01000003_gene3955	1.468e-35	149.0	COG2322@1|root,COG2322@2|Bacteria,3Y5H4@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
YHH2_k127_8239902_4	478741.JAFS01000002_gene875	3.299e-31	136.0	COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia,37GTT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
YHH2_k127_8269107_3	864702.OsccyDRAFT_2745	5.522e-47	198.0	COG2931@1|root,COG2931@2|Bacteria,1GHDS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
YHH2_k127_8269107_2	583355.Caka_2045	2.842e-51	212.0	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	murD	-	3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100	-	R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131	-	-	-	DUF1727,Mur_ligase_C,Mur_ligase_M
YHH2_k127_8269107_1	234267.Acid_2605	6.395e-67	239.0	COG2133@1|root,COG2133@2|Bacteria,3Y3FI@57723|Acidobacteria	57723|Acidobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_8269107_0	497964.CfE428DRAFT_0844	6.198e-81	283.0	COG3356@1|root,COG3356@2|Bacteria,46UC2@74201|Verrucomicrobia	2|Bacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
YHH2_k127_8336561_0	269797.Mbar_A1574	8.112e-52	192.0	COG1262@1|root,arCOG03517@2157|Archaea,2Y27Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
YHH2_k127_8336561_2	1499967.BAYZ01000090_gene4936	1.391e-22	110.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
YHH2_k127_8336561_1	545694.TREPR_0418	2.215e-25	113.0	COG1262@1|root,COG1262@2|Bacteria,2J5Y8@203691|Spirochaetes	203691|Spirochaetes	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Flavodoxin_4
YHH2_k127_8350301_0	28072.Nos7524_0852	9.849e-105	377.0	COG3266@1|root,COG3266@2|Bacteria,1GHDI@1117|Cyanobacteria,1HU9Y@1161|Nostocales	1117|Cyanobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8350301_1	497965.Cyan7822_0583	3.293e-12	81.0	COG2931@1|root,COG3210@1|root,COG5492@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1GC1J@1117|Cyanobacteria,3KJVM@43988|Cyanothece	1117|Cyanobacteria	QU	Polymorphic membrane protein Chlamydia	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin
YHH2_k127_8406587_1	1128912.GMES_3105	5.774e-190	612.0	COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,1S0S6@1236|Gammaproteobacteria,46A7Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH2_k127_8406587_3	794903.OPIT5_04755	4.5e-120	396.0	COG2152@1|root,COG2152@2|Bacteria,46YKJ@74201|Verrucomicrobia,3K8SE@414999|Opitutae	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
YHH2_k127_8406587_2	452637.Oter_3546	1.223e-156	507.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
YHH2_k127_8406587_5	497964.CfE428DRAFT_4835	5.366e-42	158.0	COG4747@1|root,COG4747@2|Bacteria,46WIS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
YHH2_k127_8406587_0	1156937.MFUM_90015	5.298e-217	682.0	COG0174@1|root,COG0174@2|Bacteria,46UCU@74201|Verrucomicrobia,37FVD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YHH2_k127_8406587_4	768671.ThimaDRAFT_3218	5.376e-44	163.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1WWT4@135613|Chromatiales	135613|Chromatiales	U	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
YHH2_k127_8409466_4	1337936.IJ00_22680	4.076e-11	68.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,DUF4625,NPCBM_assoc,PEGA
YHH2_k127_8409466_5	1396141.BATP01000056_gene3206	4.15e-06	51.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Peptidase_C11
YHH2_k127_8409466_3	1185876.BN8_00865	3.012e-62	234.0	28N78@1|root,2ZBBY@2|Bacteria,4NGF9@976|Bacteroidetes,47X4G@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
YHH2_k127_8409466_0	452637.Oter_2945	0.0	1160.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2945|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8409466_1	452637.Oter_2932	8.512e-224	709.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
YHH2_k127_8409466_2	368408.Tpen_1559	1.089e-115	389.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8422549_0	1117318.PRUB_07755	1.987e-255	817.0	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,1RPC7@1236|Gammaproteobacteria,2Q1BI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
YHH2_k127_8422549_1	497964.CfE428DRAFT_3780	1.091e-118	393.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,46TM8@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
YHH2_k127_8502565_1	497964.CfE428DRAFT_0115	1.417e-86	291.0	COG0177@1|root,COG0177@2|Bacteria,46T2G@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YHH2_k127_8502565_0	382464.ABSI01000002_gene4290	6.056e-123	434.0	COG0457@1|root,COG0457@2|Bacteria,46X09@74201|Verrucomicrobia,2IW9W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_16,TPR_2,TPR_7,TPR_8
YHH2_k127_8522717_1	497964.CfE428DRAFT_0170	3.454e-161	530.0	COG1643@1|root,COG1643@2|Bacteria,46TFT@74201|Verrucomicrobia	74201|Verrucomicrobia	L	helicase domain protein	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
YHH2_k127_8522717_2	497964.CfE428DRAFT_5019	1.144e-116	387.0	COG0077@1|root,COG0077@2|Bacteria,46U8V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
YHH2_k127_8522717_4	240016.ABIZ01000001_gene1756	7.143e-39	156.0	COG1386@1|root,COG1386@2|Bacteria,46VRU@74201|Verrucomicrobia,2IUTS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Segregation and condensation complex subunit ScpB	-	-	-	-	-	-	-	-	-	-	-	-	SMC_ScpB
YHH2_k127_8522717_3	497964.CfE428DRAFT_5017	9.151e-76	262.0	COG1354@1|root,COG1354@2|Bacteria,46UBD@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	-	-	-	-	-	-	-	-	-	SMC_ScpA
YHH2_k127_8522717_7	1156937.MFUM_290019	2.848e-05	47.0	COG2220@1|root,COG2220@2|Bacteria,46ZEV@74201|Verrucomicrobia,37GY0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
YHH2_k127_8522717_5	234267.Acid_1623	1.62e-08	59.0	COG2801@1|root,COG2801@2|Bacteria,3Y821@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
YHH2_k127_8522717_6	1403819.BATR01000011_gene422	1.719e-07	66.0	COG4932@1|root,COG5267@1|root,COG5492@1|root,COG4932@2|Bacteria,COG5267@2|Bacteria,COG5492@2|Bacteria,46TJE@74201|Verrucomicrobia,2IVHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
YHH2_k127_8522717_0	1396141.BATP01000034_gene4198	6.945e-317	1048.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_8525450_4	344747.PM8797T_23639	1.828e-31	132.0	COG1477@1|root,COG1477@2|Bacteria,2IY0F@203682|Planctomycetes	203682|Planctomycetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
YHH2_k127_8525450_2	497964.CfE428DRAFT_1935	1.196e-113	382.0	COG2870@1|root,COG2870@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,Hydrolase,PfkB
YHH2_k127_8525450_0	886293.Sinac_0542	9.333e-155	501.0	COG1915@1|root,COG1915@2|Bacteria,2IXX9@203682|Planctomycetes	203682|Planctomycetes	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8525450_1	886293.Sinac_0541	1.226e-123	402.0	COG0546@1|root,COG0546@2|Bacteria,2IZVE@203682|Planctomycetes	203682|Planctomycetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH2_k127_8525450_3	1122218.KB893653_gene1028	7.296e-47	174.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,1JUKB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
YHH2_k127_8525450_5	1403819.BATR01000100_gene3348	9.151e-23	99.0	COG0413@1|root,COG0413@2|Bacteria,46SPN@74201|Verrucomicrobia,2IU4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
YHH2_k127_8542122_2	1382359.JIAL01000001_gene1019	4.342e-110	364.0	COG0008@1|root,COG0008@2|Bacteria,3Y4TS@57723|Acidobacteria,2JKAU@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH2_k127_8542122_6	497964.CfE428DRAFT_0896	1.304e-41	160.0	COG1595@1|root,COG1595@2|Bacteria,46V3R@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_8542122_5	296591.Bpro_0806	7.551e-61	216.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,4AAWV@80864|Comamonadaceae	28216|Betaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
YHH2_k127_8542122_4	344747.PM8797T_08029	3.044e-102	343.0	COG3386@1|root,COG3386@2|Bacteria,2IXWY@203682|Planctomycetes	2|Bacteria	G	gluconolactonase	gnl	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
YHH2_k127_8542122_0	1123242.JH636434_gene3888	4.688e-151	491.0	COG1249@1|root,COG1249@2|Bacteria,2IX5H@203682|Planctomycetes	203682|Planctomycetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH2_k127_8542122_3	300852.55771566	9.157e-108	364.0	COG0508@1|root,COG0508@2|Bacteria,1WI1G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH2_k127_8542122_1	1183438.GKIL_4363	1.362e-148	507.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8542122_7	411154.GFO_1836	2.104e-10	75.0	COG1520@1|root,COG2304@1|root,COG2911@1|root,COG3209@1|root,COG1520@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,SprB
YHH2_k127_8546036_1	478741.JAFS01000002_gene933	2.942e-67	250.0	COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,37GGI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
YHH2_k127_8546036_0	497964.CfE428DRAFT_0881	3.604e-107	359.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	mviM	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_8546036_2	756272.Plabr_0617	8.891e-65	242.0	COG2211@1|root,COG2211@2|Bacteria,2IWTX@203682|Planctomycetes	203682|Planctomycetes	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
YHH2_k127_8610215_2	1382306.JNIM01000001_gene1327	1.485e-103	346.0	COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YHH2_k127_8610215_4	1254432.SCE1572_33240	1.181e-45	173.0	COG1073@1|root,COG1073@2|Bacteria,1QYFN@1224|Proteobacteria,434P1@68525|delta/epsilon subdivisions,2WZ0B@28221|Deltaproteobacteria,2Z120@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8610215_0	1303518.CCALI_01058	4.078e-166	529.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	nirH	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
YHH2_k127_8610215_1	1403819.BATR01000096_gene3149	1.186e-129	428.0	COG3540@1|root,COG3540@2|Bacteria,46VDI@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
YHH2_k127_8610215_3	314230.DSM3645_05180	2.945e-71	264.0	COG2159@1|root,COG2159@2|Bacteria,2IYMW@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
YHH2_k127_8610215_5	321327.CYA_1071	4.265e-44	172.0	COG0219@1|root,COG0219@2|Bacteria,1G5TM@1117|Cyanobacteria,1H0BA@1129|Synechococcus	1117|Cyanobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	-	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
YHH2_k127_8615398_0	478741.JAFS01000002_gene302	5.153e-198	635.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,46TH0@74201|Verrucomicrobia,37G1H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
YHH2_k127_8615398_1	1235279.C772_01648	8.52e-66	233.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,26DBP@186818|Planococcaceae	91061|Bacilli	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
YHH2_k127_8615398_2	497964.CfE428DRAFT_3166	5.594e-50	186.0	COG1597@1|root,COG1597@2|Bacteria,46SR5@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
YHH2_k127_861798_0	515635.Dtur_1560	2.099e-237	752.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH2_k127_861798_7	243275.TDE_2009	5.068e-05	54.0	COG2834@1|root,COG2834@2|Bacteria,2J5AT@203691|Spirochaetes	203691|Spirochaetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
YHH2_k127_861798_8	497964.CfE428DRAFT_6108	0.0003942	52.0	2FCZ3@1|root,3451R@2|Bacteria,46WBW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
YHH2_k127_861798_1	1303518.CCALI_01216	1.61e-85	286.0	COG0512@1|root,COG0512@2|Bacteria	2|Bacteria	EH	Glutamine amidotransferase of anthranilate synthase	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.4.2.18,2.6.1.85,4.1.3.27	ko:K01658,ko:K01664,ko:K13497	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01073,R01716	RC00010,RC00440,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2496	GATase,Glycos_trans_3N,Glycos_transf_3
YHH2_k127_861798_3	497964.CfE428DRAFT_5497	6.865e-83	283.0	COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia	74201|Verrucomicrobia	D	PFAM Cobyrinic acid ac-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YHH2_k127_861798_6	1203076.CAKF01000019_gene1256	8.284e-07	57.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,3F40M@33958|Lactobacillaceae	91061|Bacilli	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
YHH2_k127_861798_2	497964.CfE428DRAFT_2596	1.284e-84	298.0	COG0402@1|root,COG0402@2|Bacteria,46TB5@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Amidohydrolase family	ssnA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YHH2_k127_861798_5	1303518.CCALI_00238	3.756e-44	170.0	COG1028@1|root,COG1028@2|Bacteria	1303518.CCALI_00238|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
YHH2_k127_861798_4	497964.CfE428DRAFT_3334	4.227e-61	228.0	COG0156@1|root,COG0156@2|Bacteria,46TTU@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_8633248_0	1166018.FAES_0627	4.942e-101	344.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,47MH7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_8633248_1	1305737.JAFX01000001_gene3410	2.993e-71	256.0	COG1082@1|root,COG1082@2|Bacteria,4NI4H@976|Bacteroidetes,47MMY@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH2_k127_8633248_2	1499967.BAYZ01000076_gene794	2.026e-66	239.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH2_k127_8633248_3	1049564.TevJSym_ad00820	7.51e-12	70.0	COG2062@1|root,COG2062@2|Bacteria,1PKQU@1224|Proteobacteria,1TKA9@1236|Gammaproteobacteria,1J754@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
YHH2_k127_8634683_0	583355.Caka_1736	2.851e-69	265.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_8634683_2	468059.AUHA01000007_gene2704	3.703e-11	77.0	COG3386@1|root,COG3391@1|root,COG4625@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,COG4625@2|Bacteria,4NK33@976|Bacteroidetes,1IX26@117747|Sphingobacteriia	976|Bacteroidetes	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
YHH2_k127_8634683_1	1396141.BATP01000034_gene4198	3.486e-46	184.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_8635016_0	404380.Gbem_2406	9.999e-114	391.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,43T3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
YHH2_k127_8635016_1	32057.KB217478_gene3544	2.491e-14	84.0	COG1413@1|root,COG1413@2|Bacteria,1GHRB@1117|Cyanobacteria,1HSJZ@1161|Nostocales	1117|Cyanobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
YHH2_k127_8635016_2	1294265.JCM21738_5545	1.796e-08	64.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli	91061|Bacilli	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-TG,RHS_repeat
YHH2_k127_8687662_4	1123261.AXDW01000001_gene1017	0.0001375	53.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1X5BS@135614|Xanthomonadales	135614|Xanthomonadales	M	heptosyltransferase	opsX	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YHH2_k127_8687662_0	1134413.ANNK01000026_gene1469	5.728e-83	289.0	COG2327@1|root,COG2327@2|Bacteria	2|Bacteria	S	slime layer polysaccharide biosynthetic process	wgaD	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
YHH2_k127_8687662_1	1173024.KI912149_gene6199	2.446e-52	203.0	COG0438@1|root,COG0438@2|Bacteria,1G4W4@1117|Cyanobacteria,1JJUK@1189|Stigonemataceae	1117|Cyanobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YHH2_k127_8687662_2	1379698.RBG1_1C00001G1893	1.253e-25	122.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	MatE,Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
YHH2_k127_8687662_3	1089551.KE386572_gene1601	7.356e-07	60.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,Methyltransf_31
YHH2_k127_8700664_1	765911.Thivi_0693	3.407e-75	264.0	COG0784@1|root,COG2198@1|root,COG4564@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG4564@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,1X2V3@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH2_k127_8700664_0	794903.OPIT5_20035	1.166e-126	430.0	COG1409@1|root,COG3210@1|root,COG3979@1|root,COG5295@1|root,COG1409@2|Bacteria,COG3210@2|Bacteria,COG3979@2|Bacteria,COG5295@2|Bacteria,46X97@74201|Verrucomicrobia,3K9CI@414999|Opitutae	414999|Opitutae	U	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8700664_2	28444.JODQ01000018_gene7284	8.584e-29	134.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2I2T4@201174|Actinobacteria	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_2,PQQ_2
YHH2_k127_8709103_3	118173.KB235914_gene2265	1.819e-08	61.0	COG1569@1|root,COG1569@2|Bacteria,1G7ZZ@1117|Cyanobacteria,1HCQ7@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
YHH2_k127_8709103_2	1033732.CAHI01000009_gene1723	3.236e-14	77.0	COG1073@1|root,COG1073@2|Bacteria,4NG6A@976|Bacteroidetes,2FPAE@200643|Bacteroidia	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8709103_4	67332.FM21_17600	3.026e-06	57.0	COG4409@1|root,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria	201174|Actinobacteria	G	BNR Asp-box repeat	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Laminin_G_3
YHH2_k127_8709103_0	1232410.KI421421_gene3768	1.458e-139	454.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,43S1Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH2_k127_8718328_2	272134.KB731325_gene653	1.349e-29	119.0	COG1943@1|root,COG1943@2|Bacteria,1G9TK@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH2_k127_8718328_4	278957.ABEA03000097_gene786	8.978e-07	54.0	COG3209@1|root,COG3209@2|Bacteria,46VWR@74201|Verrucomicrobia,3K8JF@414999|Opitutae	414999|Opitutae	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YHH2_k127_8718328_0	1047013.AQSP01000126_gene2737	2.154e-211	665.0	COG0673@1|root,COG0673@2|Bacteria,2NRVS@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_8718328_3	1352941.M877_12005	6.526e-20	106.0	COG1082@1|root,COG1470@1|root,COG1082@2|Bacteria,COG1470@2|Bacteria,2GKFD@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase 97	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97,NPCBM,NPCBM_assoc,RicinB_lectin_2
YHH2_k127_8718328_1	398512.JQKC01000017_gene3063	2.757e-117	417.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH2_k127_8723791_4	179408.Osc7112_6188	1.374e-07	63.0	COG2931@1|root,COG2931@2|Bacteria,1G3DW@1117|Cyanobacteria,1HAZM@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,DUF4347,HemolysinCabind
YHH2_k127_8723791_3	204669.Acid345_0436	4.888e-37	148.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YHH2_k127_8723791_2	1156937.MFUM_1040009	2.501e-63	232.0	COG1612@1|root,COG1612@2|Bacteria,46T3F@74201|Verrucomicrobia,37G83@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
YHH2_k127_8723791_1	886293.Sinac_6888	2.645e-73	258.0	COG0109@1|root,COG0109@2|Bacteria,2IYUU@203682|Planctomycetes	203682|Planctomycetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
YHH2_k127_8723791_0	1156937.MFUM_700069	1.446e-100	334.0	COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia,37GA2@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
YHH2_k127_872516_2	478741.JAFS01000002_gene242	5.983e-132	433.0	COG2262@1|root,COG2262@2|Bacteria,46SP4@74201|Verrucomicrobia,37FVB@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YHH2_k127_872516_3	497964.CfE428DRAFT_2338	6.245e-67	239.0	COG0324@1|root,COG0324@2|Bacteria,46T1C@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YHH2_k127_872516_4	439235.Dalk_1768	2.706e-56	205.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2MIZH@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
YHH2_k127_872516_5	497964.CfE428DRAFT_1107	7.908e-44	166.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_872516_1	497964.CfE428DRAFT_0257	1.349e-224	727.0	COG2844@1|root,COG2844@2|Bacteria,46SI6@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
YHH2_k127_872516_7	1396141.BATP01000060_gene4765	2.748e-27	130.0	COG0028@1|root,COG2730@1|root,COG2755@1|root,COG2931@1|root,COG3506@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG0028@2|Bacteria,COG2730@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3506@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
YHH2_k127_872516_6	1236504.HMPREF2132_07780	1.938e-34	139.0	COG1051@1|root,COG1051@2|Bacteria,4NP2X@976|Bacteroidetes,2FMSZ@200643|Bacteroidia	976|Bacteroidetes	F	Hydrolase, NUDIX family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,zf-NADH-PPase
YHH2_k127_872516_0	1123242.JH636435_gene1245	0.0	1085.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
YHH2_k127_8734924_1	99598.Cal7507_1620	1.795e-243	768.0	COG0826@1|root,COG0826@2|Bacteria,1G3NG@1117|Cyanobacteria,1HM59@1161|Nostocales	1117|Cyanobacteria	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32,Peptidase_U32_C
YHH2_k127_8734924_6	1293048.CBMB010000003_gene1331	1.506e-45	176.0	COG0451@1|root,arCOG03095@2157|Archaea,2XTPI@28890|Euryarchaeota,23STT@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
YHH2_k127_8734924_3	497964.CfE428DRAFT_0777	4.943e-89	312.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
YHH2_k127_8734924_4	497964.CfE428DRAFT_0777	6.953e-66	241.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
YHH2_k127_8734924_2	497964.CfE428DRAFT_0775	5.168e-123	402.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YHH2_k127_8734924_0	1396141.BATP01000006_gene5477	1.031e-257	816.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,46TDA@74201|Verrucomicrobia,2IV8Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH2_k127_8734924_7	632518.Calow_0752	2.394e-22	98.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,42GTF@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
YHH2_k127_8734924_8	1297742.A176_01276	5.123e-16	80.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2Z2HK@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
YHH2_k127_8734924_5	1121430.JMLG01000028_gene1479	5.463e-50	181.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,260JP@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
YHH2_k127_8748456_0	595460.RRSWK_04695	1.089e-36	155.0	COG5002@1|root,COG5002@2|Bacteria,2IY3P@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YHH2_k127_8748456_1	344747.PM8797T_31088	5.369e-08	64.0	COG0515@1|root,COG0515@2|Bacteria,2IX6E@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YHH2_k127_8775315_2	1121920.AUAU01000001_gene2228	7.337e-66	236.0	COG0009@1|root,COG0009@2|Bacteria,3Y3VW@57723|Acidobacteria	57723|Acidobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
YHH2_k127_8775315_1	497964.CfE428DRAFT_1789	3.443e-144	470.0	COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
YHH2_k127_8775315_0	1156937.MFUM_680008	1.296e-184	607.0	COG0532@1|root,COG0532@2|Bacteria,46S8V@74201|Verrucomicrobia,37FYY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
YHH2_k127_8775315_4	926561.KB900623_gene1086	3.582e-15	79.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3WAT9@53433|Halanaerobiales	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
YHH2_k127_8775315_3	1396141.BATP01000057_gene2988	3.604e-51	193.0	COG0618@1|root,COG0618@2|Bacteria,46T03@74201|Verrucomicrobia,2ITUW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DHHA1 domain	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH2_k127_88143_1	67352.JODS01000024_gene3041	1.438e-21	111.0	COG4188@1|root,COG4188@2|Bacteria,2GJVV@201174|Actinobacteria	201174|Actinobacteria	M	Platelet-activating factor acetylhydrolase, plasma intracellular isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
YHH2_k127_88143_0	1122603.ATVI01000012_gene1134	7.17e-48	198.0	COG1404@1|root,COG2373@1|root,COG1404@2|Bacteria,COG2373@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1X484@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the peptidase S8 family	-	GO:0005575,GO:0005576	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,PPC,P_proprotein,Peptidase_S8
YHH2_k127_88143_3	1105029.HMPREF1137_1499	7.418e-12	79.0	COG3087@1|root,COG3211@1|root,COG3087@2|Bacteria,COG3211@2|Bacteria,2HF04@201174|Actinobacteria,4D4TG@85005|Actinomycetales	201174|Actinobacteria	D	Fibrinogen-related domains (FReDs)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_88143_2	1343740.M271_49845	3.504e-14	84.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
YHH2_k127_8927661_2	497964.CfE428DRAFT_0347	1.952e-35	139.0	2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_8927661_1	696747.NIES39_Q02130	6.386e-72	280.0	COG1520@1|root,COG1520@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP
YHH2_k127_8927661_0	497964.CfE428DRAFT_4431	1.188e-294	1001.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3227@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	CHU_C,FTP,PQQ_2,Peptidase_M36
YHH2_k127_8948958_0	452637.Oter_0894	0.0	2159.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,46U9T@74201|Verrucomicrobia,3K7GP@414999|Opitutae	414999|Opitutae	E	glutamate synthase	-	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
YHH2_k127_8948958_8	1408473.JHXO01000007_gene947	5.545e-05	54.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,2FNXT@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH2_k127_8948958_7	1121859.KB890739_gene2183	1.207e-15	79.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH2_k127_8948958_2	1396141.BATP01000057_gene2930	1.235e-138	477.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
YHH2_k127_8948958_5	497964.CfE428DRAFT_1805	3.024e-64	226.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH2_k127_8948958_1	266265.Bxe_B2149	3.142e-191	610.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1JZMS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.1.39,1.2.1.8	ko:K00128,ko:K00130,ko:K00146	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH2_k127_8948958_9	497964.CfE428DRAFT_1504	0.0003465	54.0	COG3391@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,NHL,SprB
YHH2_k127_8948958_4	1185876.BN8_03440	1.064e-95	342.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	yclG	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
YHH2_k127_8948958_3	1121468.AUBR01000017_gene2377	1.226e-117	387.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,42EVK@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM isocitrate isopropylmalate dehydrogenase	icd	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH2_k127_8948958_6	706587.Desti_2509	2.789e-53	196.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,42QJC@68525|delta/epsilon subdivisions,2WPI2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_10,TPR_16,TPR_19,TPR_4,TPR_8
YHH2_k127_8953521_1	1123070.KB899269_gene2382	1.217e-53	202.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
YHH2_k127_8953521_2	945713.IALB_1460	2.991e-29	123.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	ko:K14061	-	-	-	-	ko00000	-	-	-	Usp
YHH2_k127_8953521_0	1123242.JH636434_gene3764	1.342e-133	440.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_8980373_2	103690.17133696	2.088e-14	75.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HPUY@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YHH2_k127_8980373_0	269797.Mbar_A1995	7.771e-73	262.0	arCOG02516@1|root,arCOG02538@1|root,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,2Y7RK@28890|Euryarchaeota,2NBKX@224756|Methanomicrobia	2157|Archaea	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,He_PIG,PKD,PQQ_3,Peptidase_S8,S-layer
YHH2_k127_8980373_1	204669.Acid345_4091	1.463e-43	171.0	28NY3@1|root,2ZBVC@2|Bacteria,3Y8CE@57723|Acidobacteria,2JNAC@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9022355_2	247490.KSU1_C1637	8.973e-47	176.0	COG2930@1|root,COG2930@2|Bacteria	2|Bacteria	S	regulation of ruffle assembly	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
YHH2_k127_9022355_1	1209989.TepiRe1_1813	1.58e-113	374.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,42EMP@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ketose-bisphosphate aldolase, class-II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
YHH2_k127_9022355_0	1121403.AUCV01000020_gene3110	5.073e-121	397.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
YHH2_k127_90317_3	1123242.JH636434_gene3835	4.655e-85	302.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,2J53G@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
YHH2_k127_90317_2	794903.OPIT5_07055	2.543e-158	512.0	COG1940@1|root,COG1940@2|Bacteria,46SBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_90317_4	1128427.KB904821_gene1968	1.153e-83	286.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YHH2_k127_90317_1	1156937.MFUM_700096	6.645e-193	614.0	COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,37G7K@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	LeuA allosteric (dimerisation) domain	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
YHH2_k127_90317_7	1250006.JHZZ01000001_gene1610	2.217e-09	63.0	COG0614@1|root,COG0614@2|Bacteria,4PK1S@976|Bacteroidetes,1IME4@117743|Flavobacteriia,3VXES@52959|Polaribacter	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
YHH2_k127_90317_0	497964.CfE428DRAFT_1386	0.0	1281.0	COG0525@1|root,COG0525@2|Bacteria,46SGP@74201|Verrucomicrobia	74201|Verrucomicrobia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
YHH2_k127_90317_6	240016.ABIZ01000001_gene3295	1.151e-58	213.0	COG0483@1|root,COG0483@2|Bacteria,46T0Z@74201|Verrucomicrobia,2IU5U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YHH2_k127_90317_5	344747.PM8797T_31653	3.811e-77	279.0	2F8GG@1|root,340VA@2|Bacteria,2J3K0@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9034423_0	1396141.BATP01000034_gene4198	1.48e-251	818.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
YHH2_k127_9034423_2	240015.ACP_1538	0.0002559	46.0	COG0610@1|root,COG0610@2|Bacteria,3Y3YB@57723|Acidobacteria,2JIWJ@204432|Acidobacteriia	204432|Acidobacteriia	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
YHH2_k127_9034423_1	1157490.EL26_10740	5.124e-100	349.0	COG4412@1|root,COG4412@2|Bacteria,1UYZF@1239|Firmicutes,4HBRX@91061|Bacilli	91061|Bacilli	S	Immune inhibitor A peptidase M6	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
YHH2_k127_9038261_1	1122176.KB903598_gene4712	1.428e-45	181.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
YHH2_k127_9038261_2	497964.CfE428DRAFT_4704	4.59e-19	95.0	COG2825@1|root,COG2825@2|Bacteria,46T22@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM outer membrane chaperone Skp (OmpH)	hlpA	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
YHH2_k127_9038261_0	497964.CfE428DRAFT_4705	1.183e-79	278.0	COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YHH2_k127_9038923_4	937777.Deipe_1749	0.0001754	45.0	COG0635@1|root,COG0635@2|Bacteria,1WI1C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
YHH2_k127_9038923_0	414684.RC1_2403	1.05e-223	709.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,2JPAT@204441|Rhodospirillales	204441|Rhodospirillales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
YHH2_k127_9038923_3	278957.ABEA03000005_gene4419	2.715e-13	74.0	COG5393@1|root,COG5393@2|Bacteria,46XW8@74201|Verrucomicrobia,3K8G8@414999|Opitutae	414999|Opitutae	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
YHH2_k127_9038923_2	452637.Oter_1161	3.861e-17	85.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
YHH2_k127_9038923_1	698758.AXY_15410	2.831e-65	230.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YHH2_k127_9055389_1	1403819.BATR01000102_gene3420	6.123e-91	304.0	COG0626@1|root,COG0626@2|Bacteria,46V6V@74201|Verrucomicrobia,2IWMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
YHH2_k127_9055389_0	1009370.ALO_06298	5.085e-221	716.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4H3RH@909932|Negativicutes	909932|Negativicutes	L	HELICc2	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2
YHH2_k127_9066827_2	261292.Nit79A3_0969	2.161e-13	79.0	2DSEK@1|root,33FUB@2|Bacteria,1NI40@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082,VPEP
YHH2_k127_9066827_0	1173028.ANKO01000084_gene955	1.462e-104	377.0	COG3266@1|root,COG3266@2|Bacteria,1GHDI@1117|Cyanobacteria,1HE3S@1150|Oscillatoriales	1117|Cyanobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9066827_1	1121468.AUBR01000001_gene568	2.089e-86	300.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,42HHB@68295|Thermoanaerobacterales	186801|Clostridia	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
YHH2_k127_907539_1	1396418.BATQ01000058_gene77	1.613e-219	701.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,2ITNZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
YHH2_k127_907539_0	330214.NIDE1868	0.0	1568.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,3J0UH@40117|Nitrospirae	40117|Nitrospirae	H	Pterin binding enzyme	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
YHH2_k127_9108950_6	1313265.JNIE01000003_gene1200	8.431e-11	72.0	COG0655@1|root,COG0655@2|Bacteria,2G4ET@200783|Aquificae	200783|Aquificae	S	Flavodoxin	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_1
YHH2_k127_9108950_0	1499967.BAYZ01000081_gene1040	2.428e-116	389.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	afr	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_9108950_3	994479.GL877878_gene3434	6.769e-29	131.0	COG4733@1|root,COG4733@2|Bacteria,2I3TX@201174|Actinobacteria,4DYI4@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
YHH2_k127_9108950_5	278957.ABEA03000013_gene2639	5.639e-13	81.0	2AXAG@1|root,31P9J@2|Bacteria,46XVM@74201|Verrucomicrobia,3K8EC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9108950_4	1408473.JHXO01000009_gene3379	7.136e-14	80.0	2BXUX@1|root,32R23@2|Bacteria,4NR4Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9108950_1	382464.ABSI01000011_gene2968	1.475e-81	291.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9108950_2	1278078.G419_23849	6.101e-39	168.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4FU85@85025|Nocardiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
YHH2_k127_9113226_1	351607.Acel_1191	2.354e-45	182.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4ERF9@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
YHH2_k127_9113226_0	671143.DAMO_0750	2.846e-70	259.0	COG4122@1|root,COG4122@2|Bacteria,2NQFB@2323|unclassified Bacteria	2|Bacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
YHH2_k127_9116380_6	1142394.PSMK_20510	3.413e-48	184.0	COG0030@1|root,COG0030@2|Bacteria,2IYD7@203682|Planctomycetes	203682|Planctomycetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YHH2_k127_9116380_5	452637.Oter_2376	9.084e-55	196.0	COG1443@1|root,COG1443@2|Bacteria,46T1S@74201|Verrucomicrobia,3K84X@414999|Opitutae	414999|Opitutae	I	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH2_k127_9116380_4	1156937.MFUM_170024	7.32e-83	278.0	COG0740@1|root,COG0740@2|Bacteria,46SAB@74201|Verrucomicrobia,37G7G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YHH2_k127_9116380_2	1136177.KCA1_1795	2.728e-161	518.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,3F41K@33958|Lactobacillaceae	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
YHH2_k127_9116380_3	452637.Oter_2839	1.876e-160	516.0	COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,3K7B5@414999|Opitutae	414999|Opitutae	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH2_k127_9116380_1	1123376.AUIU01000013_gene1818	1.496e-174	554.0	COG0473@1|root,COG0473@2|Bacteria,3J0JQ@40117|Nitrospirae	40117|Nitrospirae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH2_k127_9116380_7	1168034.FH5T_14170	2.089e-31	128.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,2FRYM@200643|Bacteroidia	976|Bacteroidetes	J	S4 domain protein	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
YHH2_k127_9116380_0	344747.PM8797T_32040	2.156e-178	584.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PQQ_2,PQQ_3
YHH2_k127_9181961_1	316067.Geob_3094	2.842e-75	273.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
YHH2_k127_9181961_0	452637.Oter_4045	3.585e-160	518.0	COG0165@1|root,COG0165@2|Bacteria,46UYU@74201|Verrucomicrobia,3K76F@414999|Opitutae	414999|Opitutae	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
YHH2_k127_9181961_2	1403819.BATR01000130_gene4633	1.004e-60	227.0	COG0628@1|root,COG0628@2|Bacteria,46VTV@74201|Verrucomicrobia,2ITP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YHH2_k127_9181961_3	3075.A0A087ST02	2.796e-51	185.0	COG0345@1|root,KOG3124@2759|Eukaryota,37JXA@33090|Viridiplantae,34H6M@3041|Chlorophyta	3041|Chlorophyta	E	Belongs to the pyrroline-5-carboxylate reductase family	-	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
YHH2_k127_9195789_0	324602.Caur_0662	3.184e-19	98.0	2DSCK@1|root,32USS@2|Bacteria,2GAKK@200795|Chloroflexi,376NF@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9195789_1	1214242.B446_08255	6.237e-17	92.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
YHH2_k127_9212490_3	452637.Oter_0928	2.133e-60	218.0	COG2829@1|root,COG2829@2|Bacteria,46XUQ@74201|Verrucomicrobia,3K8AI@414999|Opitutae	414999|Opitutae	M	Phospholipase A1	-	-	-	-	-	-	-	-	-	-	-	-	PLA1
YHH2_k127_9212490_0	1267535.KB906767_gene1079	2.262e-256	800.0	COG0499@1|root,COG0499@2|Bacteria,3Y2J2@57723|Acidobacteria,2JIFV@204432|Acidobacteriia	204432|Acidobacteriia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
YHH2_k127_9212490_1	452637.Oter_3855	7.556e-180	570.0	COG0192@1|root,COG0192@2|Bacteria,46S4V@74201|Verrucomicrobia,3K7PD@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YHH2_k127_9212490_2	497964.CfE428DRAFT_2087	9.334e-104	345.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46SDC@74201|Verrucomicrobia	74201|Verrucomicrobia	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11,Methyltransf_31
YHH2_k127_9212490_4	1121022.ABENE_16225	1.905e-36	145.0	COG3533@1|root,COG3533@2|Bacteria,1MWEN@1224|Proteobacteria,2U1Q4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
YHH2_k127_9215142_3	1121920.AUAU01000009_gene1881	8.63e-40	171.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
YHH2_k127_9215142_5	9668.ENSMPUP00000015899	0.0001225	56.0	KOG3509@1|root,KOG3509@2759|Eukaryota,38X54@33154|Opisthokonta,3B9Y9@33208|Metazoa,3CYVU@33213|Bilateria,486VS@7711|Chordata,4900I@7742|Vertebrata,3JABR@40674|Mammalia,3EG5W@33554|Carnivora	33208|Metazoa	T	heparan sulfate proteoglycan	HSPG2	GO:0000323,GO:0000902,GO:0000904,GO:0001523,GO:0002119,GO:0002164,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005775,GO:0005794,GO:0005796,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006026,GO:0006027,GO:0006629,GO:0006720,GO:0006721,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006954,GO:0006996,GO:0007010,GO:0007044,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007414,GO:0007415,GO:0007417,GO:0007420,GO:0007517,GO:0008022,GO:0008037,GO:0008038,GO:0008045,GO:0008150,GO:0008152,GO:0008543,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009605,GO:0009653,GO:0009719,GO:0009790,GO:0009791,GO:0009792,GO:0009887,GO:0009892,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010605,GO:0010646,GO:0010647,GO:0010927,GO:0010941,GO:0012505,GO:0016020,GO:0016043,GO:0016101,GO:0016192,GO:0016477,GO:0016525,GO:0019222,GO:0019538,GO:0022008,GO:0022603,GO:0022607,GO:0022612,GO:0023051,GO:0023052,GO:0023056,GO:0030011,GO:0030029,GO:0030030,GO:0030036,GO:0030154,GO:0030182,GO:0030198,GO:0030203,GO:0030239,GO:0031012,GO:0031032,GO:0031175,GO:0031581,GO:0031974,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0032991,GO:0034329,GO:0034330,GO:0035088,GO:0035090,GO:0035295,GO:0040011,GO:0040012,GO:0040017,GO:0042221,GO:0042330,GO:0042493,GO:0042692,GO:0043062,GO:0043170,GO:0043202,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043900,GO:0043902,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044344,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044437,GO:0044444,GO:0044446,GO:0044449,GO:0044459,GO:0044464,GO:0044877,GO:0045197,GO:0045199,GO:0045765,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048565,GO:0048583,GO:0048584,GO:0048644,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048732,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050750,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050896,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051674,GO:0051716,GO:0055001,GO:0055002,GO:0055120,GO:0055123,GO:0060255,GO:0060278,GO:0060279,GO:0060322,GO:0060465,GO:0060548,GO:0061061,GO:0061245,GO:0061564,GO:0062023,GO:0065007,GO:0070013,GO:0070325,GO:0070848,GO:0070887,GO:0070925,GO:0071310,GO:0071363,GO:0071495,GO:0071704,GO:0071774,GO:0071840,GO:0071944,GO:0072347,GO:0072358,GO:0072359,GO:0080090,GO:0097435,GO:0097485,GO:0098657,GO:0098796,GO:0098797,GO:0099080,GO:0099081,GO:0099512,GO:0120036,GO:0120039,GO:1901135,GO:1901136,GO:1901137,GO:1901342,GO:1901343,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1902903,GO:1902904,GO:1905905,GO:1905906,GO:1905907,GO:2000026,GO:2000181,GO:2000241,GO:2000243,GO:2001260,GO:2001262	-	ko:K06255	ko04512,ko05161,ko05205,map04512,map05161,map05205	-	-	-	ko00000,ko00001,ko00535,ko04147,ko04516	-	-	-	EGF,I-set,Ig_2,Ig_3,Laminin_B,Laminin_EGF,Laminin_G_1,Laminin_G_2,Ldl_recept_a,ig
YHH2_k127_9215142_0	2340.JV46_09630	2.976e-200	636.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
YHH2_k127_9215142_1	448385.sce4706	5.435e-144	468.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2YWI0@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
YHH2_k127_9215142_2	1396141.BATP01000019_gene1674	4.109e-111	366.0	COG0437@1|root,COG0437@2|Bacteria,46UV0@74201|Verrucomicrobia,2IU11@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
YHH2_k127_9218855_3	1137281.D778_01718	2.493e-05	59.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1HYES@117743|Flavobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
YHH2_k127_9218855_1	313606.M23134_01193	7.16e-18	100.0	COG3469@1|root,COG3979@1|root,COG3469@2|Bacteria,COG3979@2|Bacteria,4PKBR@976|Bacteroidetes,47Y17@768503|Cytophagia	976|Bacteroidetes	G	Carbohydrate binding domain	-	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,CarboxypepD_reg,Glyco_hydro_18
YHH2_k127_9218855_0	1121272.KB903251_gene859	4.013e-114	413.0	COG2304@1|root,COG4257@1|root,COG2304@2|Bacteria,COG4257@2|Bacteria,2IDJM@201174|Actinobacteria,4DEGK@85008|Micromonosporales	201174|Actinobacteria	V	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HYR,VWA
YHH2_k127_9218855_2	335543.Sfum_2359	1.649e-09	72.0	COG1345@1|root,COG1345@2|Bacteria,1QVAA@1224|Proteobacteria,43BPG@68525|delta/epsilon subdivisions,2X70T@28221|Deltaproteobacteria,2MR3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9221385_0	497964.CfE428DRAFT_0776	8.443e-230	734.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001,PHP
YHH2_k127_9221385_2	66377.JOBH01000001_gene1677	3.078e-12	76.0	COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,2GKQG@201174|Actinobacteria	201174|Actinobacteria	DT	Forkhead associated domain	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE,Yop-YscD_cpl
YHH2_k127_9221385_1	1312954.KI914865_gene2851	5.756e-19	94.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,1W7T9@1268|Micrococcaceae	201174|Actinobacteria	K	Crp Fnr family	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YHH2_k127_9238424_5	1396141.BATP01000020_gene50	2.371e-07	57.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_9238424_4	269797.Mbar_A3737	3.01e-12	79.0	COG1520@1|root,COG3291@1|root,arCOG03991@1|root,arCOG02482@2157|Archaea,arCOG02508@2157|Archaea,arCOG03991@2157|Archaea,2XUI1@28890|Euryarchaeota,2NBKW@224756|Methanomicrobia	28890|Euryarchaeota	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	PKD
YHH2_k127_9238424_0	1121920.AUAU01000001_gene2269	2.895e-317	989.0	COG2864@1|root,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	2|Bacteria	C	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
YHH2_k127_9238424_1	452637.Oter_2584	4.276e-146	477.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
YHH2_k127_9238424_2	344747.PM8797T_11556	7.647e-123	411.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_9238424_3	234267.Acid_0845	7.252e-17	85.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeZ	-	-	ko:K05384,ko:K05386	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	HEAT_2
YHH2_k127_9248087_2	368408.Tpen_1559	1.736e-22	104.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9248087_3	246197.MXAN_5265	1.27e-12	82.0	COG3055@1|root,COG3055@2|Bacteria,1QE0Q@1224|Proteobacteria,4318S@68525|delta/epsilon subdivisions,2WX4P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glyoxal oxidase N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,Glyoxal_oxid_N,Kelch_1
YHH2_k127_9248087_0	1173020.Cha6605_6196	1.165e-57	208.0	COG1670@1|root,COG1670@2|Bacteria,1G6FK@1117|Cyanobacteria	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YHH2_k127_9248087_1	240015.ACP_0367	3.287e-53	207.0	COG2755@1|root,COG5301@1|root,COG2755@2|Bacteria,COG5301@2|Bacteria,3Y82Q@57723|Acidobacteria,2JN5M@204432|Acidobacteriia	204432|Acidobacteriia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9251371_3	240016.ABIZ01000001_gene2630	5.343e-52	196.0	COG1477@1|root,COG1477@2|Bacteria,46VJI@74201|Verrucomicrobia,2IW89@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ApbE family	-	-	-	-	-	-	-	-	-	-	-	-	ApbE
YHH2_k127_9251371_0	382464.ABSI01000013_gene1719	2.907e-130	431.0	COG0673@1|root,COG0673@2|Bacteria,46TK3@74201|Verrucomicrobia,2IVGR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_9251371_2	243090.RB4846	2.687e-102	360.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
YHH2_k127_9251371_1	497964.CfE428DRAFT_6049	1.226e-114	387.0	COG0673@1|root,COG0673@2|Bacteria,46U0A@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH2_k127_9251371_4	240016.ABIZ01000001_gene1588	9.58e-08	58.0	COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia,2ITZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH2_k127_9288647_1	221288.JH992901_gene2709	2.193e-46	192.0	COG2319@1|root,COG5635@1|root,COG2319@2|Bacteria,COG5635@2|Bacteria,1FZVW@1117|Cyanobacteria,1JJ8J@1189|Stigonemataceae	1117|Cyanobacteria	T	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat,NACHT,Pentapeptide,WD40
YHH2_k127_9288647_0	234267.Acid_4531	1.568e-51	209.0	COG1387@1|root,COG1387@2|Bacteria,3Y6GG@57723|Acidobacteria	57723|Acidobacteria	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH2_k127_9288647_2	485915.Dret_0711	1.92e-17	89.0	2CGNA@1|root,3301B@2|Bacteria,1N74P@1224|Proteobacteria,42VID@68525|delta/epsilon subdivisions,2WRHN@28221|Deltaproteobacteria,2MD48@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yippee-Mis18
YHH2_k127_9295821_3	1184267.A11Q_489	5.565e-08	55.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2MSS1@213481|Bdellovibrionales,2WINJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
YHH2_k127_9295821_0	794903.OPIT5_16815	0.0	1366.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia,3K7UQ@414999|Opitutae	414999|Opitutae	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH2_k127_9295821_2	582515.KR51_00000010	2.254e-16	93.0	COG1572@1|root,COG2304@1|root,COG2931@1|root,COG3210@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1G39H@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,HemolysinCabind,RHS_repeat
YHH2_k127_9295821_1	1123508.JH636440_gene2008	6.518e-114	375.0	COG1760@1|root,COG1760@2|Bacteria,2IXXH@203682|Planctomycetes	203682|Planctomycetes	E	COG1760 L-serine deaminase	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
YHH2_k127_9300785_2	224911.27356599	8.341e-22	105.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2U1Z0@28211|Alphaproteobacteria,3K6A5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.7.7.49	ko:K00986,ko:K15342	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	Cas_Cas1,GIIM,RVT_1
YHH2_k127_9300785_0	391038.Bphy_7609	1.409e-255	805.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2VK01@28216|Betaproteobacteria,1K0XA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH2_k127_9300785_3	1038869.AXAN01000205_gene2324	1.991e-10	64.0	2DSZ1@1|root,33HZU@2|Bacteria,1PXZ0@1224|Proteobacteria,2WD9I@28216|Betaproteobacteria,1K9SN@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9300785_1	1123508.JH636448_gene7487	8.175e-89	305.0	COG3464@1|root,COG3464@2|Bacteria,2J1EU@203682|Planctomycetes	203682|Planctomycetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
YHH2_k127_9306738_7	452637.Oter_2718	2.326e-07	55.0	COG1758@1|root,COG1758@2|Bacteria,46T94@74201|Verrucomicrobia,3K8FM@414999|Opitutae	414999|Opitutae	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
YHH2_k127_9306738_3	945713.IALB_1744	1.248e-43	165.0	COG0691@1|root,COG0691@2|Bacteria	2|Bacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YHH2_k127_9306738_5	794903.OPIT5_19880	7.179e-20	91.0	COG0227@1|root,COG0227@2|Bacteria,46TBF@74201|Verrucomicrobia,3K89C@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
YHH2_k127_9306738_4	452637.Oter_0650	7.389e-29	132.0	COG4726@1|root,COG4726@2|Bacteria,46YMK@74201|Verrucomicrobia,3K9UG@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9306738_8	1408422.JHYF01000001_gene2807	0.0004327	49.0	2E3CE@1|root,32YBQ@2|Bacteria,1VF4G@1239|Firmicutes	1239|Firmicutes	S	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH2_k127_9306738_1	1201290.M902_2686	2.587e-66	231.0	COG1838@1|root,COG1838@2|Bacteria,1R33Y@1224|Proteobacteria,43DIX@68525|delta/epsilon subdivisions,2MUNI@213481|Bdellovibrionales,2WK6Z@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit	-	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
YHH2_k127_9306738_0	1353529.M899_0311	2.939e-121	395.0	COG1951@1|root,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,42MC7@68525|delta/epsilon subdivisions,2WKIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
YHH2_k127_9306738_9	452637.Oter_1533	0.0009658	51.0	COG5074@1|root,COG5074@2|Bacteria,46XTA@74201|Verrucomicrobia,3K7YA@414999|Opitutae	414999|Opitutae	U	SNAP receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9306738_2	452637.Oter_2441	3.492e-58	211.0	COG0284@1|root,COG0284@2|Bacteria,46T17@74201|Verrucomicrobia,3K7VT@414999|Opitutae	414999|Opitutae	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
YHH2_k127_9306738_6	756272.Plabr_2500	2.924e-13	69.0	COG0304@1|root,COG0304@2|Bacteria,2IWRA@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH2_k127_9333490_3	1385935.N836_29340	1.883e-52	194.0	COG2367@1|root,COG2367@2|Bacteria,1G0DG@1117|Cyanobacteria,1H7IN@1150|Oscillatoriales	1117|Cyanobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
YHH2_k127_9333490_0	886293.Sinac_0402	9.453e-217	716.0	COG1196@1|root,COG1196@2|Bacteria,2IYCW@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9333490_4	1095772.CAHH01000028_gene2566	8.648e-18	84.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria	201174|Actinobacteria	J	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
YHH2_k127_9333490_2	1396141.BATP01000003_gene4993	3.289e-140	467.0	COG0471@1|root,COG0471@2|Bacteria,46TTA@74201|Verrucomicrobia,2IU1V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
YHH2_k127_9333490_5	404380.Gbem_3436	6.3e-08	60.0	COG5512@1|root,COG5512@2|Bacteria,1N6KK@1224|Proteobacteria,42TK4@68525|delta/epsilon subdivisions,2WQQS@28221|Deltaproteobacteria,43VF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
YHH2_k127_9333490_1	935948.KE386494_gene695	9.691e-150	497.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,42FYE@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Glycoside hydrolase family 42 domain protein	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
YHH2_k127_9381449_1	661478.OP10G_2626	1.577e-183	592.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
YHH2_k127_9381449_0	1123261.AXDW01000005_gene2633	7.389e-191	612.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,1RRMM@1236|Gammaproteobacteria,1X2YX@135614|Xanthomonadales	135614|Xanthomonadales	E	phospho-2-dehydro-3-deoxyheptonate aldolase	dhs1	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
YHH2_k127_9384509_2	1460635.JCM19038_1751	0.0009477	51.0	COG1409@1|root,COG1409@2|Bacteria,1TPQQ@1239|Firmicutes,4HC2W@91061|Bacilli	91061|Bacilli	G	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Laminin_G_3,Metallophos,SLH
YHH2_k127_9384509_0	755732.Fluta_1212	2.741e-44	177.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1I0BV@117743|Flavobacteriia	976|Bacteroidetes	M	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
YHH2_k127_9384509_1	160799.PBOR_01905	2.603e-25	115.0	COG1409@1|root,COG3250@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
YHH2_k127_9466364_1	497964.CfE428DRAFT_5932	2.405e-83	284.0	COG1131@1|root,COG1131@2|Bacteria,46TZ8@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH2_k127_9466364_0	1168034.FH5T_07165	1.405e-105	356.0	COG0613@1|root,COG0613@2|Bacteria,4NHZ5@976|Bacteroidetes,2FQW5@200643|Bacteroidia	976|Bacteroidetes	G	Domain of unknown function	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001,PHP
YHH2_k127_9466364_2	264732.Moth_2111	3.216e-20	104.0	COG0407@1|root,COG0407@2|Bacteria,1V5GX@1239|Firmicutes,24J7A@186801|Clostridia	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH2_k127_9467496_3	313628.LNTAR_12216	3.309e-48	196.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_9467496_2	543728.Vapar_2851	7.956e-55	195.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2WBQC@28216|Betaproteobacteria,4AI59@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YHH2_k127_9467496_1	344747.PM8797T_20084	1.765e-91	331.0	COG3391@1|root,COG3391@2|Bacteria,2IY8U@203682|Planctomycetes	203682|Planctomycetes	M	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH2_k127_9467496_0	661478.OP10G_2798	7.609e-99	344.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
YHH2_k127_9483840_4	497964.CfE428DRAFT_4948	2.219e-42	163.0	COG0438@1|root,COG0438@2|Bacteria,46UG2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH2_k127_9483840_0	1403819.BATR01000099_gene3304	2.757e-185	591.0	COG0644@1|root,COG0644@2|Bacteria,46U5W@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
YHH2_k127_9483840_5	497964.CfE428DRAFT_5040	6.061e-35	142.0	COG3161@1|root,COG3161@2|Bacteria,46WDJ@74201|Verrucomicrobia	74201|Verrucomicrobia	H	chorismate lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9483840_1	240016.ABIZ01000001_gene3202	6.116e-174	557.0	COG0635@1|root,COG0635@2|Bacteria,46U2R@74201|Verrucomicrobia,2IWKM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YHH2_k127_9483840_3	1403819.BATR01000118_gene4177	2.187e-83	291.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia,2IWIN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
YHH2_k127_9483840_2	1340493.JNIF01000003_gene1929	3.971e-132	433.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	MA20_31690	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH2_k127_9515243_3	1267535.KB906767_gene1479	7.173e-25	104.0	COG0148@1|root,COG0148@2|Bacteria,3Y2IT@57723|Acidobacteria,2JI6Q@204432|Acidobacteriia	57723|Acidobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	-	-	-	-	-	-	-	-	-	-	Enolase_C,Enolase_N
YHH2_k127_9515243_2	1173022.Cri9333_3711	5.321e-54	201.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M6@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_4
YHH2_k127_9515243_0	497964.CfE428DRAFT_6291	3.833e-168	533.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Copper-bind,Cytochrom_C,Laminin_G_3
YHH2_k127_9515243_1	481448.Minf_2259	5.301e-76	263.0	COG0084@1|root,COG0084@2|Bacteria,46SKF@74201|Verrucomicrobia,37GKS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YHH2_k127_9552585_4	28072.Nos7524_0852	1.013e-105	377.0	COG3266@1|root,COG3266@2|Bacteria,1GHDI@1117|Cyanobacteria,1HU9Y@1161|Nostocales	1117|Cyanobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9552585_9	261292.Nit79A3_0969	2.254e-13	79.0	2DSEK@1|root,33FUB@2|Bacteria,1NI40@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082,VPEP
YHH2_k127_9552585_6	1265505.ATUG01000001_gene3993	1.016e-67	241.0	COG4313@1|root,COG4313@2|Bacteria,1R6GU@1224|Proteobacteria,43BI4@68525|delta/epsilon subdivisions,2X6WJ@28221|Deltaproteobacteria,2MKN8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YHH2_k127_9552585_1	452637.Oter_0816	4.329e-217	681.0	COG1350@1|root,COG1350@2|Bacteria	2|Bacteria	E	tryptophan synthase activity	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH2_k127_9552585_2	240016.ABIZ01000001_gene4797	3.544e-174	560.0	COG3104@1|root,COG3104@2|Bacteria,46UAC@74201|Verrucomicrobia,2IU1T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
YHH2_k127_9552585_0	349741.Amuc_1769	2.94e-240	786.0	COG0553@1|root,COG0553@2|Bacteria,46YZ0@74201|Verrucomicrobia,2ITIC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH2_k127_9552585_11	324925.Ppha_0345	3.899e-08	57.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
YHH2_k127_9552585_7	1356852.N008_15650	3.525e-59	228.0	COG1520@1|root,COG3291@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,4NEVC@976|Bacteroidetes	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9552585_10	425104.Ssed_3626	8.364e-12	78.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF5128
YHH2_k127_9552585_3	1168034.FH5T_01575	4.171e-134	442.0	COG1520@1|root,COG1520@2|Bacteria,4P15Y@976|Bacteroidetes,2FWBU@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2
YHH2_k127_9552585_5	429009.Adeg_1744	1.269e-86	295.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,42GGT@68295|Thermoanaerobacterales	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
YHH2_k127_9552585_8	497964.CfE428DRAFT_6473	6.775e-45	166.0	COG1071@1|root,COG1071@2|Bacteria,46UAY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
YHH2_k127_9556290_3	1396141.BATP01000043_gene1929	1.077e-100	374.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_9556290_5	1122179.KB890442_gene1152	5.506e-42	181.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
YHH2_k127_9556290_7	1123248.KB893381_gene1089	2.116e-07	66.0	COG1345@1|root,COG2931@1|root,COG3055@1|root,COG3386@1|root,COG1345@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3386@2|Bacteria,4NK33@976|Bacteroidetes,1IX26@117747|Sphingobacteriia	976|Bacteroidetes	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9556290_0	497964.CfE428DRAFT_4373	0.0	1153.0	COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia	74201|Verrucomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH2_k127_9556290_1	481448.Minf_0157	0.0	1045.0	COG0187@1|root,COG0187@2|Bacteria,46SDH@74201|Verrucomicrobia,37GC3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH2_k127_9556290_2	1056820.KB900629_gene1721	5.777e-189	596.0	COG0524@1|root,COG0524@2|Bacteria,1QNWF@1224|Proteobacteria,1RRZR@1236|Gammaproteobacteria,2PNXE@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
YHH2_k127_9556290_6	1174504.AJTN02000018_gene1908	9.681e-20	92.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,1ZB5Z@1386|Bacillus	91061|Bacilli	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	mtnU	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
YHH2_k127_9556290_4	1403819.BATR01000181_gene6101	9.513e-56	201.0	COG0318@1|root,COG0318@2|Bacteria,46T7I@74201|Verrucomicrobia,2IVBG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
YHH2_k127_9566399_3	1307759.JOMJ01000003_gene2150	1.233e-21	103.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2MB1P@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
YHH2_k127_9566399_0	1499967.BAYZ01000118_gene3277	9.793e-212	669.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
YHH2_k127_9566399_1	497964.CfE428DRAFT_5266	3.277e-157	508.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_9566399_2	583355.Caka_0473	4.377e-68	237.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C,PA14
YHH2_k127_9609803_4	583355.Caka_1071	1.403e-21	97.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia,3K7KC@414999|Opitutae	414999|Opitutae	H	acetolactate synthase large subunit	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YHH2_k127_9609803_3	794903.OPIT5_20760	1.827e-30	137.0	2AXAG@1|root,31P9J@2|Bacteria,46XVM@74201|Verrucomicrobia,3K8EC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9609803_1	497964.CfE428DRAFT_4603	1.649e-75	267.0	COG0349@1|root,COG0349@2|Bacteria,46SUU@74201|Verrucomicrobia	74201|Verrucomicrobia	L	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
YHH2_k127_9609803_0	639282.DEFDS_0642	2.43e-126	428.0	COG0318@1|root,COG0318@2|Bacteria,2GETC@200930|Deferribacteres	200930|Deferribacteres	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
YHH2_k127_9609803_2	595460.RRSWK_04460	1.276e-68	242.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
YHH2_k127_9663265_6	344747.PM8797T_12733	5.014e-26	120.0	COG0457@1|root,COG0457@2|Bacteria,2J3ZR@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9663265_0	530564.Psta_3389	1.092e-140	460.0	COG1520@1|root,COG1520@2|Bacteria,2IWWY@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH2_k127_9663265_2	1268240.ATFI01000005_gene4564	4.044e-85	299.0	COG5434@1|root,COG5434@2|Bacteria,4NID5@976|Bacteroidetes,2FMZR@200643|Bacteroidia,4AP7B@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
YHH2_k127_9663265_3	452637.Oter_1758	1.215e-57	204.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
YHH2_k127_9663265_4	945713.IALB_0431	3.818e-52	194.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
YHH2_k127_9663265_1	439235.Dalk_3235	1.646e-98	335.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
YHH2_k127_9685894_1	1122176.KB903565_gene3379	1.314e-14	87.0	COG2304@1|root,COG2304@2|Bacteria,4PKD0@976|Bacteroidetes,1IXV1@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
YHH2_k127_9685894_2	292459.STH718	1.576e-09	71.0	COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	ko:K13276,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,PPC,Peptidase_S8
YHH2_k127_9714259_0	903818.KI912269_gene112	0.0	1350.0	COG0366@1|root,COG3408@1|root,COG0366@2|Bacteria,COG3408@2|Bacteria,3Y2ZW@57723|Acidobacteria	57723|Acidobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
YHH2_k127_9714259_1	880072.Desac_0511	3.594e-13	73.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria,2MRN8@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, family 39	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
YHH2_k127_9715096_0	439235.Dalk_3231	4.207e-139	467.0	COG0457@1|root,COG0457@2|Bacteria	439235.Dalk_3231|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9715096_3	344747.PM8797T_06335	3.572e-30	136.0	COG2730@1|root,COG2730@2|Bacteria,2IWW8@203682|Planctomycetes	203682|Planctomycetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
YHH2_k127_9715096_1	1123368.AUIS01000028_gene1325	2.378e-68	237.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
YHH2_k127_9802305_2	886293.Sinac_6718	1.031e-60	234.0	2EDSX@1|root,337NB@2|Bacteria,2J11B@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9802305_0	1267535.KB906767_gene773	2.512e-203	636.0	COG0524@1|root,COG0524@2|Bacteria,3Y3DE@57723|Acidobacteria,2JI9I@204432|Acidobacteriia	204432|Acidobacteriia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH2_k127_9802305_1	497964.CfE428DRAFT_6510	3.72e-94	322.0	COG0845@1|root,COG0845@2|Bacteria,46SKN@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YHH2_k127_9816279_3	697284.ERIC2_c23330	5.602e-10	72.0	COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,26R4P@186822|Paenibacillaceae	91061|Bacilli	E	Thermolysin metallopeptidase, alpha-helical domain	nprB	GO:0005575,GO:0005576	3.4.24.28	ko:K01400,ko:K08777	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
YHH2_k127_9816279_2	498211.CJA_1292	1.55e-19	104.0	COG2374@1|root,COG3391@1|root,COG5184@1|root,COG2374@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	mtsC	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD,Reprolysin_4,SLH,TSP_3
YHH2_k127_9816279_4	1123054.KB907711_gene361	5.164e-09	69.0	COG1404@1|root,COG3266@1|root,COG1404@2|Bacteria,COG3266@2|Bacteria,1RC5K@1224|Proteobacteria,1S3I9@1236|Gammaproteobacteria,1WXY7@135613|Chromatiales	135613|Chromatiales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH2_k127_9816279_0	452637.Oter_2033	6.429e-176	557.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
YHH2_k127_9826455_4	96561.Dole_0165	2.542e-37	142.0	COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,433D2@68525|delta/epsilon subdivisions,2WY7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TfoX N-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
YHH2_k127_9826455_1	313612.L8106_01142	6.539e-73	277.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1G02E@1117|Cyanobacteria,1H9TQ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,SBBP
YHH2_k127_9826455_0	1192034.CAP_0893	3.109e-78	294.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
YHH2_k127_9826455_2	203124.Tery_1036	8.436e-59	220.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1FZWQ@1117|Cyanobacteria,1HHTJ@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
YHH2_k127_9826455_3	1122604.JONR01000003_gene1574	2.287e-38	148.0	COG2940@1|root,COG2940@2|Bacteria,1RIQT@1224|Proteobacteria	1224|Proteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
YHH2_k127_9826455_6	1121285.AUFK01000014_gene2617	5.694e-10	73.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1HY9Y@117743|Flavobacteriia,3ZREB@59732|Chryseobacterium	976|Bacteroidetes	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
YHH2_k127_9826455_5	1121920.AUAU01000009_gene1881	1.198e-20	108.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
YHH2_k127_9832495_1	497964.CfE428DRAFT_0782	1.085e-154	507.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,46UE9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
YHH2_k127_9832495_9	696369.KI912183_gene110	1.311e-13	79.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,2629S@186807|Peptococcaceae	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
YHH2_k127_9832495_6	382464.ABSI01000023_gene525	2.443e-37	151.0	COG2928@1|root,COG2928@2|Bacteria,46VCC@74201|Verrucomicrobia,2IUXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
YHH2_k127_9832495_8	518766.Rmar_0237	4.342e-17	87.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,1FJIK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
YHH2_k127_9832495_4	497964.CfE428DRAFT_6337	6.618e-115	378.0	COG1702@1|root,COG1702@2|Bacteria,46S7S@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
YHH2_k127_9832495_5	224325.AF_2211	6.186e-51	185.0	COG0537@1|root,arCOG00419@2157|Archaea,2XWGT@28890|Euryarchaeota,2466N@183980|Archaeoglobi	183980|Archaeoglobi	F	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
YHH2_k127_9832495_7	497964.CfE428DRAFT_5353	3.821e-37	160.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
YHH2_k127_9832495_10	391600.ABRU01000025_gene1292	3.788e-13	83.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2KFH3@204458|Caulobacterales	204458|Caulobacterales	K	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH2_k127_9832495_2	926560.KE387023_gene1701	1.352e-150	509.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YHH2_k127_9832495_0	452637.Oter_2216	7.65e-222	728.0	COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,46Z3U@74201|Verrucomicrobia,3KA3G@414999|Opitutae	74201|Verrucomicrobia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
YHH2_k127_9832495_3	306281.AJLK01000008_gene5848	9.181e-119	392.0	COG2334@1|root,COG2334@2|Bacteria,1G1QD@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
YHH2_k127_9835405_3	391009.Tmel_1008	0.0002608	54.0	COG2374@1|root,COG4085@1|root,COG2374@2|Bacteria,COG4085@2|Bacteria,2GCXZ@200918|Thermotogae	200918|Thermotogae	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
YHH2_k127_9835405_1	765420.OSCT_3130	9.597e-67	256.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
YHH2_k127_9835405_2	452637.Oter_2946	3.331e-62	235.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	Collagen_bind_2,DUF4038,DUF5060,DUF721
YHH2_k127_9835405_0	1379698.RBG1_1C00001G1601	1.755e-168	544.0	COG0480@1|root,COG0480@2|Bacteria,2NNSV@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YHH2_k127_9868160_0	583355.Caka_1052	2.438e-180	578.0	COG1154@1|root,COG1154@2|Bacteria,46SAU@74201|Verrucomicrobia,3K7CY@414999|Opitutae	414999|Opitutae	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
YHH2_k127_9868160_2	1123277.KB893197_gene6105	5.251e-47	186.0	COG1520@1|root,COG3266@1|root,COG1520@2|Bacteria,COG3266@2|Bacteria,4NQBS@976|Bacteroidetes,47QPM@768503|Cytophagia	976|Bacteroidetes	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
YHH2_k127_9868160_1	583355.Caka_0200	5.462e-73	254.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
YHH2_k127_9870398_4	983544.Lacal_1288	6.764e-17	93.0	COG2374@1|root,COG2374@2|Bacteria,4NKW3@976|Bacteroidetes,1I0VD@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	LTD
YHH2_k127_9870398_3	269796.Rru_A3564	5.365e-42	160.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2TRW1@28211|Alphaproteobacteria,2JT4Q@204441|Rhodospirillales	204441|Rhodospirillales	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_6,Hydrolase_like,NTP_transferase
YHH2_k127_9870398_2	338963.Pcar_1946	1.007e-70	247.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43TY0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cytidylyltransferase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
YHH2_k127_9870398_0	497964.CfE428DRAFT_3303	7.248e-241	754.0	COG0504@1|root,COG0504@2|Bacteria,46S8K@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
YHH2_k127_9870398_1	497964.CfE428DRAFT_2028	4.222e-85	304.0	COG0285@1|root,COG0285@2|Bacteria,46SKD@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Mur ligase middle domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH2_k127_9881508_1	1268622.AVS7_04453	6.004e-38	166.0	COG3637@1|root,COG5563@1|root,COG3637@2|Bacteria,COG5563@2|Bacteria,1QVUE@1224|Proteobacteria	1224|Proteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	fn3
YHH2_k127_9881508_0	1396141.BATP01000060_gene4730	3.305e-52	213.0	COG3210@1|root,COG3291@1|root,COG4733@1|root,COG4870@1|root,COG5279@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4870@2|Bacteria,COG5279@2|Bacteria,46XT0@74201|Verrucomicrobia,2IWHU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9925228_3	59374.Fisuc_2588	1.271e-05	48.0	2C7PP@1|root,33K9Q@2|Bacteria	2|Bacteria	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	ko:K19295	-	-	-	-	ko00000	-	-	-	ALGX
YHH2_k127_9925228_0	1167006.UWK_01804	1.469e-95	327.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42UTJ@68525|delta/epsilon subdivisions,2X5J6@28221|Deltaproteobacteria,2MKI5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
YHH2_k127_9925228_1	756272.Plabr_2893	2.2e-71	248.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
YHH2_k127_9925228_2	913865.DOT_1386	1.409e-13	84.0	COG2247@1|root,COG4733@1|root,COG2247@2|Bacteria,COG4733@2|Bacteria,1UZS5@1239|Firmicutes,24FE6@186801|Clostridia,2600Z@186807|Peptococcaceae	186801|Clostridia	M	cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Endopep_inhib,fn3
YHH2_k127_9932404_1	1167006.UWK_00700	5.215e-08	58.0	2DR98@1|root,33ARN@2|Bacteria,1NHFU@1224|Proteobacteria,42X3T@68525|delta/epsilon subdivisions,2WSSX@28221|Deltaproteobacteria,2MMBR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
YHH2_k127_9932404_0	933262.AXAM01000191_gene3347	4.9e-08	59.0	COG3668@1|root,COG3668@2|Bacteria,1N8DJ@1224|Proteobacteria,42VZU@68525|delta/epsilon subdivisions,2WRB9@28221|Deltaproteobacteria,2MM4U@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9932404_2	1961.JOAK01000010_gene6637	0.0002916	46.0	COG0451@1|root,COG0451@2|Bacteria,2GZUV@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K13318,ko:K13322,ko:K16439,ko:K19857	ko00523,ko01055,ko01130,map00523,map01055,map01130	M00798,M00799,M00800	R06436,R06629,R11042,R11047	RC00182,RC00261	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH2_k127_9932983_2	1246474.ANBE01000053_gene1004	3.462e-12	79.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C,Glyco_hydro_125
YHH2_k127_9932983_3	794903.OPIT5_21635	0.0003737	53.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C,Glycos_transf_2
YHH2_k127_9932983_1	530564.Psta_4448	3.087e-16	82.0	2CKQA@1|root,30U0C@2|Bacteria,2J1CW@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9932983_0	1150600.ADIARSV_0055	4.314e-152	499.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes,1IWWX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_993809_1	338963.Pcar_2327	1.002e-53	196.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,43SZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
YHH2_k127_993809_0	926550.CLDAP_25880	4.948e-57	211.0	COG1609@1|root,COG1609@2|Bacteria,2G8RS@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
YHH2_k127_993809_2	1403819.BATR01000042_gene1260	6.077e-11	68.0	COG3952@1|root,COG3952@2|Bacteria,46T9Z@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N,T2SSG
YHH2_k127_9968778_3	1123070.KB899249_gene311	1.094e-112	373.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,2ITZ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH2_k127_9968778_10	452637.Oter_0478	4.576e-58	207.0	COG1143@1|root,COG1143@2|Bacteria,46SNT@74201|Verrucomicrobia,3K7UR@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
YHH2_k127_9968778_14	478741.JAFS01000002_gene661	4.075e-27	116.0	COG0839@1|root,COG0839@2|Bacteria,46T5P@74201|Verrucomicrobia,37GUV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YHH2_k127_9968778_12	481448.Minf_2214	3.342e-32	127.0	COG0713@1|root,COG0713@2|Bacteria,46SX4@74201|Verrucomicrobia,37GV9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YHH2_k127_9968778_0	1156937.MFUM_940007	6.066e-193	620.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,37GBS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
YHH2_k127_9968778_2	478741.JAFS01000002_gene664	5.33e-128	428.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,37GAQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YHH2_k127_9968778_4	635013.TherJR_2028	3.227e-106	361.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YHH2_k127_9968778_13	478741.JAFS01000001_gene1519	1.06e-29	134.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,37GX8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
YHH2_k127_9968778_5	497964.CfE428DRAFT_2172	3.6e-104	354.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46SRG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
YHH2_k127_9968778_9	1396418.BATQ01000117_gene4521	1.102e-75	267.0	COG0142@1|root,COG0142@2|Bacteria,46SKW@74201|Verrucomicrobia,2ITYJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH2_k127_9968778_11	240016.ABIZ01000001_gene3616	1.033e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH2_k127_9968778_6	497964.CfE428DRAFT_2392	6.505e-98	327.0	COG0266@1|root,COG0266@2|Bacteria,46SKI@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
YHH2_k127_9968778_7	1121428.DESHY_70012___1	1.04e-94	315.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,260V1@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
YHH2_k127_9968778_16	1519464.HY22_12795	3.75e-20	93.0	COG1828@1|root,COG1828@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.2.6,6.3.5.3	ko:K01923,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463,R04591	RC00010,RC00064,RC00162,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
YHH2_k127_9968778_8	497964.CfE428DRAFT_2041	8.585e-93	332.0	COG1452@1|root,COG1452@2|Bacteria,46SJX@74201|Verrucomicrobia	74201|Verrucomicrobia	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	imp	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
YHH2_k127_9968778_1	497964.CfE428DRAFT_2042	6.71e-134	435.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH2_k127_9968778_15	1121887.AUDK01000015_gene869	2.404e-24	114.0	28K60@1|root,2Z9UH@2|Bacteria,4NHE6@976|Bacteroidetes,1IEXU@117743|Flavobacteriia,2NYKK@237|Flavobacterium	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
YHH2_k127_9972798_1	1303518.CCALI_01306	6.294e-116	398.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Gln_amidase,HYR,RHS_repeat
YHH2_k127_9972798_0	314230.DSM3645_08677	0.0	1013.0	COG1249@1|root,COG1249@2|Bacteria,2IYMR@203682|Planctomycetes	203682|Planctomycetes	C	Glucose inhibited division protein A	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
YHH2_k127_9972798_2	1121439.dsat_0706	2e-99	338.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria,2M8HM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,PAS_8
YHH2_k127_9972798_3	1227739.Hsw_PA0020	9.38e-29	121.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
YHH2_k127_9973672_3	497964.CfE428DRAFT_4495	1.68e-104	346.0	COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
YHH2_k127_9973672_8	497964.CfE428DRAFT_4494	1.69e-19	91.0	2DS8G@1|root,33EZT@2|Bacteria,46T9M@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
YHH2_k127_9973672_5	497964.CfE428DRAFT_4493	2.204e-42	162.0	COG0711@1|root,COG0711@2|Bacteria,46SYI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
YHH2_k127_9973672_7	1403819.BATR01000049_gene1414	3.457e-29	121.0	COG0712@1|root,COG0712@2|Bacteria,46TC4@74201|Verrucomicrobia,2IUUI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	ATP synthase delta (OSCP) subunit	-	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
YHH2_k127_9973672_0	497964.CfE428DRAFT_4491	3.128e-245	765.0	COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
YHH2_k127_9973672_4	497964.CfE428DRAFT_4490	5.554e-93	314.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
YHH2_k127_9973672_1	497964.CfE428DRAFT_4489	5.845e-239	745.0	COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH2_k127_9973672_6	1403819.BATR01000049_gene1418	1.171e-30	125.0	COG0355@1|root,COG0355@2|Bacteria,46T0F@74201|Verrucomicrobia,2IUNC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
YHH2_k127_9973672_9	661478.OP10G_2998	9.172e-12	68.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
YHH2_k127_9973672_2	1111479.AXAR01000008_gene2285	2.117e-142	465.0	COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli	91061|Bacilli	U	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	araE	GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	-	ko:K02100	-	-	-	-	ko00000,ko02000	2.A.1.1.2	-	-	Sugar_tr
YHH2_k127_9983379_6	926569.ANT_20080	2.464e-25	123.0	COG1520@1|root,COG1520@2|Bacteria,2G945@200795|Chloroflexi	200795|Chloroflexi	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9983379_0	575540.Isop_1803	5.593e-197	634.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
YHH2_k127_9983379_3	1121396.KB893109_gene1893	1.199e-66	232.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,42RN4@68525|delta/epsilon subdivisions,2WP37@28221|Deltaproteobacteria,2MK0T@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM Isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
YHH2_k127_9983379_1	1232410.KI421412_gene411	2.433e-85	297.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
YHH2_k127_9983379_4	880073.Calab_1267	4.294e-43	166.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Paired_CXXCH_1
YHH2_k127_9983379_2	338969.Rfer_0256	9.566e-80	280.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2VNUX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YHH2_k127_9983379_5	880073.Calab_1271	3.479e-38	156.0	COG3005@1|root,COG3005@2|Bacteria,2NQ90@2323|unclassified Bacteria	2|Bacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YHH2_k127_9989723_2	349741.Amuc_1290	1.995e-14	81.0	COG0823@1|root,COG1262@1|root,COG0823@2|Bacteria,COG1262@2|Bacteria,46TMC@74201|Verrucomicrobia,2IVG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH2_k127_9989723_1	1305737.JAFX01000001_gene1703	1.164e-37	153.0	COG0438@1|root,COG0438@2|Bacteria,4NWCX@976|Bacteroidetes,47YNM@768503|Cytophagia	976|Bacteroidetes	M	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
YHH2_k127_9989723_0	661478.OP10G_0633	3.326e-266	828.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
## 2788 queries scanned
## Total time (seconds): 49.02860236167908
## Rate: 56.86 q/s