## Wed Dec 17 12:14:34 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/YHH3_bin.61.fa -m mmseqs --itype genome -o YHH3_bin.61 --output_dir /data/result/bins/wyx/egg/YHH3_bin.61 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YHH3_k127_10000245_3	382464.ABSI01000012_gene2247	6.663e-34	134.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia,2ITT9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
YHH3_k127_10000245_2	382464.ABSI01000012_gene2246	2.681e-98	329.0	COG0548@1|root,COG0548@2|Bacteria,46SH9@74201|Verrucomicrobia,2ITVB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Amino acid kinase family	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
YHH3_k127_10000245_0	794903.OPIT5_17105	1.68e-155	500.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,3K76X@414999|Opitutae	414999|Opitutae	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH3_k127_10000245_1	583355.Caka_0160	1.256e-112	372.0	COG0078@1|root,COG0078@2|Bacteria,46SA5@74201|Verrucomicrobia,3K73T@414999|Opitutae	414999|Opitutae	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YHH3_k127_10000245_4	382464.ABSI01000012_gene2243	1.361e-12	67.0	COG0137@1|root,COG0137@2|Bacteria,46SCU@74201|Verrucomicrobia,2ITYG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
YHH3_k127_10001117_3	1120968.AUBX01000011_gene3290	3.119e-05	51.0	COG2755@1|root,COG2755@2|Bacteria,4NIBN@976|Bacteroidetes,47NY7@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH3_k127_10001117_2	1123070.KB899262_gene1686	1.462e-68	240.0	COG2197@1|root,COG2197@2|Bacteria,46XIF@74201|Verrucomicrobia,2IW0D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_10001117_0	595460.RRSWK_04252	5.464e-194	627.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
YHH3_k127_10001117_1	382464.ABSI01000012_gene2012	2.215e-119	425.0	COG1629@1|root,COG1629@2|Bacteria,46U2X@74201|Verrucomicrobia	74201|Verrucomicrobia	M	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_10007343_1	382464.ABSI01000020_gene232	2.083e-112	373.0	COG4166@1|root,COG4166@2|Bacteria,46TR7@74201|Verrucomicrobia,2IWMV@203494|Verrucomicrobiae	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iECABU_c1320.ECABU_c15240,iECNA114_1301.ECNA114_1414,iECSF_1327.ECSF_1224,iNRG857_1313.NRG857_06385,iUMNK88_1353.UMNK88_1667	SBP_bac_5
YHH3_k127_10007343_2	583355.Caka_1811	2.923e-80	276.0	COG1387@1|root,COG1387@2|Bacteria,46U67@74201|Verrucomicrobia,3K8DP@414999|Opitutae	414999|Opitutae	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
YHH3_k127_10007343_0	452637.Oter_1904	3.835e-167	536.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,3K7NF@414999|Opitutae	74201|Verrucomicrobia	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH3_k127_10016551_1	1396141.BATP01000003_gene4970	0.0006884	52.0	COG4625@1|root,COG4625@2|Bacteria,46XGM@74201|Verrucomicrobia,2IVV5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
YHH3_k127_10016551_0	324925.Ppha_0603	1.579e-05	49.0	COG5433@1|root,COG5433@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
YHH3_k127_10035014_0	234267.Acid_4012	9.241e-163	542.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10035014_1	1121904.ARBP01000017_gene5163	9.501e-114	372.0	COG3828@1|root,COG3828@2|Bacteria,4NFMU@976|Bacteroidetes,47K27@768503|Cytophagia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
YHH3_k127_10035014_2	1282876.BAOK01000001_gene1851	1.244e-20	93.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,4BS1T@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4994,Sulfatase,Sulfatase_C
YHH3_k127_10056775_9	394221.Mmar10_2646	3.701e-29	117.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,43Z82@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YHH3_k127_10056775_4	1198232.CYCME_1952	4.873e-125	407.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,460RS@72273|Thiotrichales	72273|Thiotrichales	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
YHH3_k127_10056775_3	382464.ABSI01000010_gene3269	3.567e-149	480.0	COG3608@1|root,COG3608@2|Bacteria	2|Bacteria	G	succinylglutamate desuccinylase aspartoacylase	doeB	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
YHH3_k127_10056775_1	382464.ABSI01000010_gene3268	2.852e-174	555.0	COG0189@1|root,COG0189@2|Bacteria,46Z9I@74201|Verrucomicrobia,2ITQ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	RimK
YHH3_k127_10056775_8	382464.ABSI01000010_gene3267	2.954e-45	168.0	COG4067@1|root,COG4067@2|Bacteria,46XTD@74201|Verrucomicrobia,2IWIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
YHH3_k127_10056775_2	1123242.JH636434_gene5289	7.067e-150	487.0	COG0673@1|root,COG0673@2|Bacteria,2IX34@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_10056775_7	690850.Desaf_3777	1.508e-52	193.0	COG4843@1|root,COG4843@2|Bacteria,1REIP@1224|Proteobacteria,42S29@68525|delta/epsilon subdivisions,2WNWG@28221|Deltaproteobacteria,2MB4S@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
YHH3_k127_10056775_0	382464.ABSI01000010_gene3270	1.839e-198	626.0	COG0334@1|root,COG0334@2|Bacteria,46S9K@74201|Verrucomicrobia,2ITH4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YHH3_k127_10056775_6	1123070.KB899250_gene604	7.966e-56	199.0	COG0783@1|root,COG0783@2|Bacteria,46VAF@74201|Verrucomicrobia,2IUPW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
YHH3_k127_10056775_5	700598.Niako_0548	9.231e-58	205.0	COG2080@1|root,COG2080@2|Bacteria,4NMVV@976|Bacteroidetes,1IXEY@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
YHH3_k127_10061212_2	1089550.ATTH01000001_gene2179	3.223e-51	191.0	COG4191@1|root,COG4191@2|Bacteria,4PM6B@976|Bacteroidetes,1FIJK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH3_k127_10061212_3	1340493.JNIF01000003_gene3629	8.731e-41	160.0	COG3132@1|root,COG3132@2|Bacteria,3Y50M@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
YHH3_k127_10061212_0	452637.Oter_2855	1.501e-102	339.0	COG0745@1|root,COG0745@2|Bacteria,46VWY@74201|Verrucomicrobia,3K7WH@414999|Opitutae	414999|Opitutae	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH3_k127_10061212_4	1304885.AUEY01000008_gene2112	2.128e-33	131.0	COG0140@1|root,COG0140@2|Bacteria	2|Bacteria	E	phosphoribosyl-ATP diphosphatase activity	hisE	GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31,5.3.1.16	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037,R04640	RC00002,RC00945,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186,iYO844.BSU34860	PRA-CH,PRA-PH
YHH3_k127_10061212_1	1304885.AUEY01000008_gene2113	2.842e-76	261.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WIY9@28221|Deltaproteobacteria,2MHVV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
YHH3_k127_10111980_1	595460.RRSWK_04205	2.141e-101	345.0	COG3119@1|root,COG3119@2|Bacteria,2J24M@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_10111980_2	452637.Oter_3093	1.046e-73	263.0	COG2730@1|root,COG2730@2|Bacteria,46XJ7@74201|Verrucomicrobia,3K99G@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
YHH3_k127_10111980_0	313628.LNTAR_15742	5.173e-144	470.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_10111980_3	595460.RRSWK_07082	1.283e-68	242.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_10114515_1	452637.Oter_4633	2.839e-118	396.0	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,3K73Q@414999|Opitutae	414999|Opitutae	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
YHH3_k127_10114515_0	452637.Oter_4632	3.891e-119	395.0	COG0743@1|root,COG0743@2|Bacteria,46S90@74201|Verrucomicrobia,3K7BM@414999|Opitutae	414999|Opitutae	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
YHH3_k127_10114603_1	452637.Oter_3511	3.011e-119	397.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_10114603_0	1168034.FH5T_18780	4.901e-155	503.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,2FQ3G@200643|Bacteroidia	976|Bacteroidetes	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
YHH3_k127_10114603_2	240016.ABIZ01000001_gene764	4.506e-79	276.0	COG3119@1|root,COG3119@2|Bacteria,46ZJS@74201|Verrucomicrobia,2IVBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_10121440_0	1384056.N787_07330	1.554e-94	333.0	COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,1X3ZY@135614|Xanthomonadales	135614|Xanthomonadales	P	Oar protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YHH3_k127_10122362_5	161528.ED21_20779	1.216e-25	114.0	2FGC9@1|root,3488G@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
YHH3_k127_10122362_2	272134.KB731324_gene3229	4.345e-73	266.0	COG5002@1|root,COG5002@2|Bacteria,1GQDS@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YHH3_k127_10122362_0	111780.Sta7437_2445	8.345e-85	287.0	COG0745@1|root,COG0745@2|Bacteria,1FZXT@1117|Cyanobacteria,3VHUS@52604|Pleurocapsales	1117|Cyanobacteria	KT	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH3_k127_10122362_3	1280944.HY17_17825	2.279e-50	184.0	COG0454@1|root,COG0456@2|Bacteria,1RH71@1224|Proteobacteria,2UB0M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH3_k127_10122362_1	1165841.SULAR_09504	2.318e-77	265.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42RAV@68525|delta/epsilon subdivisions,2YR7T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
YHH3_k127_10122362_4	48698.ENSPFOP00000016779	2.962e-50	188.0	COG0673@1|root,KOG2741@2759|Eukaryota,38I4R@33154|Opisthokonta,3BGBJ@33208|Metazoa,3D1TW@33213|Bilateria,4813A@7711|Chordata,48WIV@7742|Vertebrata,49TGT@7898|Actinopterygii	33208|Metazoa	GQ	Dihydrodiol dehydrogenase (dimeric)	DHDH	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006091,GO:0008150,GO:0008152,GO:0008746,GO:0009055,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0016651,GO:0016652,GO:0019321,GO:0019323,GO:0022900,GO:0042732,GO:0042843,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0047837,GO:0055114,GO:0071704,GO:1901575	1.1.1.179,1.3.1.20	ko:K00078	ko00040,ko00980,map00040,map00980	-	R01430,R07015	RC00066,RC00891	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_10127406_0	382464.ABSI01000005_gene1136	2.01e-104	351.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,46TTA@74201|Verrucomicrobia,2IU1V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
YHH3_k127_10127406_2	497964.CfE428DRAFT_0276	4.883e-60	213.0	COG1959@1|root,COG1959@2|Bacteria,46SPI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH3_k127_10127406_1	998674.ATTE01000001_gene2822	2.353e-64	224.0	COG1051@1|root,COG1051@2|Bacteria,1RKG8@1224|Proteobacteria,1T15E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH3_k127_10127406_3	1313421.JHBV01000041_gene3603	8.297e-34	140.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
YHH3_k127_10173122_1	316057.RPD_0580	1.873e-26	120.0	COG2030@1|root,COG2030@2|Bacteria,1RC8D@1224|Proteobacteria	1224|Proteobacteria	I	PFAM MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
YHH3_k127_10173122_0	392499.Swit_1600	1.032e-58	212.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TUFX@28211|Alphaproteobacteria,2K8FT@204457|Sphingomonadales	204457|Sphingomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.7	ko:K15868	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
YHH3_k127_10174251_0	1499967.BAYZ01000076_gene807	7.654e-74	252.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	gutB	-	1.1.1.14,1.1.1.303,1.1.1.4	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	M00014	R00875,R01896,R02855,R02946,R10504	RC00085,RC00102,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
YHH3_k127_10174251_1	402777.KB235904_gene4712	8.554e-53	204.0	COG1914@1|root,COG1914@2|Bacteria,1G4SX@1117|Cyanobacteria,1H86R@1150|Oscillatoriales	1117|Cyanobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
YHH3_k127_10174251_2	497964.CfE428DRAFT_3022	7.99e-32	127.0	COG2363@1|root,COG2363@2|Bacteria,46T86@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
YHH3_k127_10174251_3	1408322.JHYK01000005_gene513	0.0003866	53.0	COG4447@1|root,COG4447@2|Bacteria,1VHBV@1239|Firmicutes,24UA6@186801|Clostridia	186801|Clostridia	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
YHH3_k127_1017692_2	1123236.KB899390_gene3505	0.0003852	45.0	COG3712@1|root,COG3712@2|Bacteria,1QFP6@1224|Proteobacteria,1RZAU@1236|Gammaproteobacteria,4654J@72275|Alteromonadaceae	1236|Gammaproteobacteria	PT	Domain of unknown function (DUF4974)	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
YHH3_k127_1017692_1	452637.Oter_3503	5.962e-33	134.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_1017692_0	595460.RRSWK_05201	3.639e-122	401.0	COG3507@1|root,COG3507@2|Bacteria,2J27X@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10204148_0	1219084.AP014508_gene1648	4.031e-175	566.0	COG3333@1|root,COG3333@2|Bacteria,2GDV9@200918|Thermotogae	200918|Thermotogae	S	PFAM Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
YHH3_k127_10204148_1	1219084.AP014508_gene1650	1.096e-105	353.0	COG3181@1|root,COG3181@2|Bacteria	2|Bacteria	E	Tripartite tricarboxylate transporter family receptor	MA20_15805	-	-	-	-	-	-	-	-	-	-	-	TctC
YHH3_k127_10204148_2	1274374.CBLK010000061_gene596	1.049e-31	130.0	2CAEK@1|root,2ZCPG@2|Bacteria,1U07Z@1239|Firmicutes,4I9IQ@91061|Bacilli,271MJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10208457_0	861299.J421_1735	1.057e-65	237.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
YHH3_k127_10212643_0	583355.Caka_0710	2.784e-82	280.0	COG1189@1|root,COG1189@2|Bacteria,46SM8@74201|Verrucomicrobia,3K7BI@414999|Opitutae	414999|Opitutae	J	S4 RNA-binding domain	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
YHH3_k127_10212643_1	583355.Caka_0711	1.046e-65	234.0	COG0061@1|root,COG0061@2|Bacteria,46SUQ@74201|Verrucomicrobia,3K7CE@414999|Opitutae	414999|Opitutae	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
YHH3_k127_10212643_3	452637.Oter_2145	7.2e-31	131.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,3K80X@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
YHH3_k127_10212643_2	313612.L8106_17742	3.407e-36	148.0	COG5360@1|root,COG5360@2|Bacteria,1G4V0@1117|Cyanobacteria	1117|Cyanobacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
YHH3_k127_10224274_0	583355.Caka_1791	7.482e-77	268.0	COG0196@1|root,COG0196@2|Bacteria,46UCC@74201|Verrucomicrobia,3K7G1@414999|Opitutae	414999|Opitutae	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
YHH3_k127_10224274_1	583355.Caka_1520	8.822e-76	264.0	COG0483@1|root,COG0483@2|Bacteria,46VJG@74201|Verrucomicrobia,3K83G@414999|Opitutae	414999|Opitutae	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YHH3_k127_10224274_2	583355.Caka_1065	3.61e-49	178.0	COG0115@1|root,COG0115@2|Bacteria,46S9W@74201|Verrucomicrobia,3K7I4@414999|Opitutae	414999|Opitutae	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YHH3_k127_10227873_6	1122931.AUAE01000042_gene2496	5.181e-22	98.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,2FQHR@200643|Bacteroidia	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_10227873_2	452637.Oter_2993	1.539e-168	542.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2,MFS_3
YHH3_k127_10227873_7	1396141.BATP01000052_gene3441	3.106e-07	59.0	COG3637@1|root,COG3637@2|Bacteria,46XQK@74201|Verrucomicrobia,2IWDK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
YHH3_k127_10227873_4	1347369.CCAD010000041_gene871	5.551e-119	392.0	COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HA9Z@91061|Bacilli,1ZB8Z@1386|Bacillus	91061|Bacilli	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_10227873_3	382464.ABSI01000013_gene1513	7.483e-121	396.0	COG4124@1|root,COG4124@2|Bacteria,46TGN@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl hydrolase family 26	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
YHH3_k127_10227873_0	382464.ABSI01000010_gene3883	4.42e-270	849.0	COG4993@1|root,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia,2ITXC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YHH3_k127_10227873_5	945713.IALB_2924	6.556e-35	135.0	COG0011@1|root,COG0011@2|Bacteria	2|Bacteria	H	TIGRFAM Protein of	yqgV	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	DUF1385,Thiamine_BP
YHH3_k127_10227873_1	518766.Rmar_0522	9.158e-188	614.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1FJQW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	haloacid dehalogenase-like hydrolase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
YHH3_k127_10250379_0	382464.ABSI01000012_gene2184	2.492e-66	248.0	COG1629@1|root,COG1629@2|Bacteria,46TVI@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_10250379_1	452637.Oter_3766	6.33e-43	177.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_10258697_0	497964.CfE428DRAFT_1946	5.895e-188	603.0	COG2010@1|root,COG2010@2|Bacteria,46V03@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
YHH3_k127_10271106_0	313628.LNTAR_07344	7.319e-83	294.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_10271106_1	243090.RB13155	1.433e-49	183.0	COG3119@1|root,COG3119@2|Bacteria,2IX69@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_10279760_0	794903.OPIT5_16865	1.17e-70	254.0	COG1609@1|root,COG1609@2|Bacteria,46V4U@74201|Verrucomicrobia,3K980@414999|Opitutae	414999|Opitutae	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
YHH3_k127_10279760_1	755178.Cyan10605_2049	3.942e-44	184.0	COG4773@1|root,COG4773@2|Bacteria,1G2Z8@1117|Cyanobacteria	1117|Cyanobacteria	P	COGs COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	AMIN,Plug,TonB_dep_Rec
YHH3_k127_10298521_0	1123508.JH636442_gene3829	3.832e-69	252.0	COG2755@1|root,COG2755@2|Bacteria,2IWTR@203682|Planctomycetes	203682|Planctomycetes	E	sialic acid-specific 9-O-acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
YHH3_k127_10309855_0	794903.OPIT5_22870	6.344e-67	258.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YHH3_k127_10327009_3	713587.THITH_07410	1.007e-66	230.0	COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,1T0C7@1236|Gammaproteobacteria,1X2MB@135613|Chromatiales	135613|Chromatiales	O	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
YHH3_k127_10327009_1	1283300.ATXB01000001_gene995	6.905e-80	274.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1XEER@135618|Methylococcales	135618|Methylococcales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
YHH3_k127_10327009_0	1444711.CCJF01000005_gene1483	6.875e-133	433.0	COG3842@1|root,COG3842@2|Bacteria,2JFST@204428|Chlamydiae	204428|Chlamydiae	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
YHH3_k127_10327009_2	765952.PUV_07600	4.483e-74	255.0	COG1176@1|root,COG1176@2|Bacteria,2JG99@204428|Chlamydiae	204428|Chlamydiae	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
YHH3_k127_10333643_3	382464.ABSI01000010_gene3353	2.873e-20	100.0	COG1629@1|root,COG1629@2|Bacteria	382464.ABSI01000010_gene3353|-	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10333643_2	392500.Swoo_3834	1.23e-27	125.0	COG3712@1|root,COG3712@2|Bacteria,1QFP6@1224|Proteobacteria,1RZAU@1236|Gammaproteobacteria,2QE0N@267890|Shewanellaceae	1236|Gammaproteobacteria	PT	FecR protein	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
YHH3_k127_10333643_1	452637.Oter_3503	1.12e-27	119.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_10333643_0	1122931.AUAE01000031_gene2866	2.338e-189	606.0	COG1653@1|root,COG1653@2|Bacteria,4NG6U@976|Bacteroidetes,2FRMG@200643|Bacteroidia,2310A@171551|Porphyromonadaceae	976|Bacteroidetes	G	Periplasmic copper-binding protein (NosD)	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Beta_helix,DUF1565
YHH3_k127_10348846_0	997884.HMPREF1068_02702	1.274e-260	839.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia,4AP3C@815|Bacteroidaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NPCBM
YHH3_k127_10348846_1	1454007.JAUG01000007_gene2188	9.19e-47	174.0	COG0526@1|root,COG0526@2|Bacteria,4NQ70@976|Bacteroidetes,1IXI5@117747|Sphingobacteriia	976|Bacteroidetes	CO	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
YHH3_k127_10348846_3	1396418.BATQ01000017_gene4160	1.869e-08	67.0	COG3266@1|root,COG3266@2|Bacteria,46VKK@74201|Verrucomicrobia,2IW2X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
YHH3_k127_10348846_2	1453501.JELR01000002_gene361	1.102e-21	109.0	COG1520@1|root,COG3266@1|root,COG5183@1|root,COG1520@2|Bacteria,COG3266@2|Bacteria,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,468SY@72275|Alteromonadaceae	1236|Gammaproteobacteria	A	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8,TSP_3
YHH3_k127_10352612_3	382464.ABSI01000020_gene173	9.318e-28	119.0	COG3156@1|root,COG3156@2|Bacteria,46VZT@74201|Verrucomicrobia,2IUG2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
YHH3_k127_10352612_4	583355.Caka_1638	2.03e-25	115.0	COG4795@1|root,COG4795@2|Bacteria,46WEK@74201|Verrucomicrobia,3K851@414999|Opitutae	414999|Opitutae	U	General secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH3_k127_10352612_5	583355.Caka_1637	1.385e-20	99.0	2FF2I@1|root,3470U@2|Bacteria,46W1E@74201|Verrucomicrobia,3K8ET@414999|Opitutae	414999|Opitutae	S	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
YHH3_k127_10352612_6	583355.Caka_1636	7.85e-14	78.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	VP0657	-	-	ko:K02457,ko:K02672,ko:K08084,ko:K08085	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	GspH,N_methyl,PilS
YHH3_k127_10352612_2	794903.OPIT5_25370	1.219e-35	140.0	COG2165@1|root,COG2165@2|Bacteria,46W6A@74201|Verrucomicrobia,3K883@414999|Opitutae	414999|Opitutae	NU	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
YHH3_k127_10352612_0	382464.ABSI01000010_gene3470	5.014e-110	367.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	-	-	2.4.1.315,2.4.1.46	ko:K03429,ko:K03715	ko00561,ko01100,map00561,map01100	-	R02689,R02691,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
YHH3_k127_10352612_1	278957.ABEA03000041_gene2195	4.094e-94	315.0	COG0304@1|root,COG0304@2|Bacteria,46UQ4@74201|Verrucomicrobia,3K78C@414999|Opitutae	414999|Opitutae	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH3_k127_10363825_2	487796.Flav2ADRAFT_1551	1.843e-12	68.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,1HZS8@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_10363825_0	661478.OP10G_0991	5.29e-267	860.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,F5_F8_type_C,Glyco_hydro_38,Glyco_hydro_38C
YHH3_k127_10363825_1	1127673.GLIP_1199	1.959e-189	598.0	COG1914@1|root,COG1914@2|Bacteria,1R9SX@1224|Proteobacteria,1RZ2E@1236|Gammaproteobacteria,46DMK@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
YHH3_k127_10376685_1	1121904.ARBP01000013_gene362	7.87e-195	619.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,47PH6@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_10376685_0	497964.CfE428DRAFT_1941	1.589e-219	695.0	COG3119@1|root,COG3119@2|Bacteria,46TQV@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_10376685_3	1396141.BATP01000030_gene3702	1.736e-161	547.0	COG3934@1|root,COG5520@1|root,COG3934@2|Bacteria,COG5520@2|Bacteria,46Z5X@74201|Verrucomicrobia,2IWQJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10376685_4	1121904.ARBP01000055_gene494	5.334e-133	439.0	COG5520@1|root,COG5520@2|Bacteria	2|Bacteria	M	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.136,3.2.1.55,3.2.1.8	ko:K01181,ko:K15921,ko:K15924	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43,GH5	-	Beta_helix,Binary_toxB_2,Binary_toxB_3,CBM_6,CW_binding_1,Dockerin_1,Glyco_hydro_10,Glyco_hydro_30,Glyco_hydro_30C,Glyco_hydro_43,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin
YHH3_k127_10376685_2	929713.NIASO_02000	1.044e-182	606.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,1IRH6@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
YHH3_k127_10376685_6	1499967.BAYZ01000009_gene5361	2.919e-106	349.0	COG0274@1|root,COG0274@2|Bacteria,2NP8Z@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
YHH3_k127_10376685_8	309799.DICTH_0472	5.108e-37	153.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_10376685_5	1191523.MROS_0115	2.205e-118	396.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2,MFS_3
YHH3_k127_10376685_7	382464.ABSI01000010_gene3216	1.29e-100	337.0	COG0657@1|root,COG0657@2|Bacteria,46V5N@74201|Verrucomicrobia,2IWK2@203494|Verrucomicrobiae	2|Bacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
YHH3_k127_10376685_9	794903.OPIT5_17560	1.967e-17	91.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529,ko:K03435,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
YHH3_k127_10398781_2	452637.Oter_2726	1.152e-85	294.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
YHH3_k127_10398781_3	485915.Dret_1332	1.863e-84	287.0	COG0204@1|root,COG0204@2|Bacteria,1PY44@1224|Proteobacteria,42NR4@68525|delta/epsilon subdivisions,2WKKQ@28221|Deltaproteobacteria,2MAGC@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH3_k127_10398781_0	583355.Caka_2556	4.208e-163	523.0	COG0172@1|root,COG0172@2|Bacteria,46S70@74201|Verrucomicrobia,3K7B7@414999|Opitutae	414999|Opitutae	J	PFAM tRNA synthetase class II (G H P and S)	-	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YHH3_k127_10398781_4	583355.Caka_1751	2.257e-69	253.0	COG0037@1|root,COG0037@2|Bacteria,46YXN@74201|Verrucomicrobia,3K8AF@414999|Opitutae	414999|Opitutae	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
YHH3_k127_10398781_1	382464.ABSI01000005_gene1337	1.491e-154	497.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,2ITNZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
YHH3_k127_10433614_5	756272.Plabr_2982	1.023e-20	91.0	COG3540@1|root,COG3540@2|Bacteria,2J1R1@203682|Planctomycetes	203682|Planctomycetes	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10433614_1	243090.RB1828	1.538e-197	622.0	COG3540@1|root,COG3540@2|Bacteria,2J1R1@203682|Planctomycetes	203682|Planctomycetes	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10433614_3	243090.RB1827	2.677e-78	273.0	28NZX@1|root,2ZBWN@2|Bacteria,2J276@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10433614_0	452637.Oter_4535	9.032e-299	941.0	COG3525@1|root,COG4733@1|root,COG3525@2|Bacteria,COG4733@2|Bacteria,46UX5@74201|Verrucomicrobia,3K8TM@414999|Opitutae	414999|Opitutae	G	Glycosyl hydrolase, family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10433614_2	743720.Psefu_3060	2.595e-104	353.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria,1YW5X@136845|Pseudomonas putida group	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	glpT	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0008643,GO:0015075,GO:0015103,GO:0015114,GO:0015144,GO:0015166,GO:0015168,GO:0015291,GO:0015297,GO:0015301,GO:0015315,GO:0015318,GO:0015527,GO:0015698,GO:0015711,GO:0015748,GO:0015791,GO:0015793,GO:0015794,GO:0015850,GO:0016020,GO:0022804,GO:0022857,GO:0034219,GO:0034220,GO:0035435,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:0099516,GO:1901264,GO:1901618	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	iECH74115_1262.ECH74115_3377,iECIAI39_1322.ECIAI39_2383,iECSP_1301.ECSP_3115,iECs_1301.ECs3125,iEcSMS35_1347.EcSMS35_2392,iG2583_1286.G2583_2780,iSFV_1184.SFV_2312,iZ_1308.Z3498	MFS_1
YHH3_k127_10433614_4	314230.DSM3645_07580	9.942e-59	213.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
YHH3_k127_10441335_4	583355.Caka_0971	9.331e-127	434.0	COG3525@1|root,COG3525@2|Bacteria,46UX5@74201|Verrucomicrobia,3K8TM@414999|Opitutae	414999|Opitutae	G	Glycosyl hydrolase, family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10441335_2	234267.Acid_4012	1.516e-170	570.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10441335_7	469381.Dpep_1446	8.732e-112	375.0	COG3493@1|root,COG3493@2|Bacteria,3TC1U@508458|Synergistetes	508458|Synergistetes	C	2-hydroxycarboxylate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	2HCT
YHH3_k127_10441335_5	649747.HMPREF0083_04416	2.906e-120	392.0	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,26QSG@186822|Paenibacillaceae	91061|Bacilli	I	3-hydroxyisobutyrate dehydrogenase	glxR	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
YHH3_k127_10441335_0	497964.CfE428DRAFT_5426	3.763e-253	798.0	COG1680@1|root,COG1680@2|Bacteria,46WGY@74201|Verrucomicrobia	74201|Verrucomicrobia	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10441335_3	404589.Anae109_3618	1.273e-155	502.0	COG3875@1|root,COG3875@2|Bacteria,1R79Y@1224|Proteobacteria,42PGD@68525|delta/epsilon subdivisions,2WMB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
YHH3_k127_10441335_1	1297581.H919_06526	2.343e-203	648.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli	91061|Bacilli	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
YHH3_k127_10441335_6	926550.CLDAP_02640	1.416e-117	387.0	COG0277@1|root,COG0277@2|Bacteria,2G85C@200795|Chloroflexi	200795|Chloroflexi	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YHH3_k127_10456899_0	583355.Caka_0740	5.369e-249	775.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia,3K7JS@414999|Opitutae	414999|Opitutae	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
YHH3_k127_10456899_1	411464.DESPIG_01570	1.844e-20	94.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2M8JZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
YHH3_k127_10474850_2	382464.ABSI01000010_gene3367	2.346e-139	459.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia,2IVM0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
YHH3_k127_10474850_1	382464.ABSI01000010_gene3368	5.19e-161	517.0	COG4102@1|root,COG4102@2|Bacteria,46T50@74201|Verrucomicrobia,2IUKB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH3_k127_10474850_5	382464.ABSI01000011_gene3012	9.361e-51	186.0	COG2094@1|root,COG2094@2|Bacteria,46VAR@74201|Verrucomicrobia,2IV0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Methylpurine-DNA glycosylase (MPG)	-	-	-	-	-	-	-	-	-	-	-	-	Pur_DNA_glyco
YHH3_k127_10474850_6	1123070.KB899251_gene740	2.188e-33	134.0	COG1321@1|root,COG1321@2|Bacteria,46VZN@74201|Verrucomicrobia,2IUJN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
YHH3_k127_10474850_4	1121403.AUCV01000065_gene4169	1.487e-54	203.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
YHH3_k127_10474850_3	278957.ABEA03000150_gene4018	4.829e-96	324.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
YHH3_k127_10474850_0	1121403.AUCV01000065_gene4167	2.443e-195	622.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2MIW3@213118|Desulfobacterales	2|Bacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
YHH3_k127_10475187_0	452637.Oter_0004	1.416e-91	319.0	COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia,3K7BP@414999|Opitutae	414999|Opitutae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	-	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
YHH3_k127_10498676_0	620914.JH621249_gene3340	2.396e-66	240.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH3_k127_10553307_5	583355.Caka_0356	3.94e-63	228.0	COG3894@1|root,COG3894@2|Bacteria,46VH9@74201|Verrucomicrobia,3K8AT@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445
YHH3_k127_10553307_2	382464.ABSI01000010_gene3486	4.708e-87	293.0	COG0145@1|root,COG0145@2|Bacteria,46VJ0@74201|Verrucomicrobia	74201|Verrucomicrobia	EQ	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
YHH3_k127_10553307_3	452637.Oter_3657	1.562e-78	276.0	COG2207@1|root,COG2207@2|Bacteria,46YE0@74201|Verrucomicrobia,3K9DW@414999|Opitutae	414999|Opitutae	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
YHH3_k127_10553307_4	452637.Oter_3658	5.434e-78	265.0	COG5012@1|root,COG5012@2|Bacteria,46V56@74201|Verrucomicrobia,3K7ZT@414999|Opitutae	414999|Opitutae	S	Methionine synthase B12-binding module cap domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
YHH3_k127_10553307_0	278957.ABEA03000093_gene4635	1.418e-191	608.0	arCOG03330@1|root,2Z82Q@2|Bacteria	2|Bacteria	S	PFAM Methanol-cobalamin methyltransferase B subunit	-	-	2.1.1.90	ko:K04480	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R04384,R09098	RC00035,RC01144,RC01145,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	MtaB
YHH3_k127_10553307_7	1504981.KO116_3490	8.97e-33	139.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RPKP@1236|Gammaproteobacteria,1XIRM@135619|Oceanospirillales	135619|Oceanospirillales	S	Cobalamin synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
YHH3_k127_10553307_1	1121929.KB898669_gene3257	7.558e-100	336.0	COG3940@1|root,COG4932@1|root,COG3940@2|Bacteria,COG4932@2|Bacteria,1TRHI@1239|Firmicutes,4H9PB@91061|Bacilli,4700K@74385|Gracilibacillus	91061|Bacilli	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
YHH3_k127_10553307_6	1499967.BAYZ01000050_gene2788	4.22e-55	194.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	uxaC	GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528	UxaC
YHH3_k127_10557025_3	583355.Caka_2053	7.269e-142	474.0	COG1674@1|root,COG1674@2|Bacteria,46SCV@74201|Verrucomicrobia,3K7AY@414999|Opitutae	414999|Opitutae	D	FtsK/SpoIIIE family	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YHH3_k127_10557025_4	794903.OPIT5_04130	3.915e-111	370.0	COG0263@1|root,COG0263@2|Bacteria,46SWM@74201|Verrucomicrobia,3K78E@414999|Opitutae	414999|Opitutae	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
YHH3_k127_10557025_8	382464.ABSI01000011_gene2535	1.667e-55	199.0	COG0233@1|root,COG0233@2|Bacteria,46V49@74201|Verrucomicrobia,2IUA0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
YHH3_k127_10557025_6	583355.Caka_2856	3.338e-103	346.0	COG0528@1|root,COG0528@2|Bacteria,46S4W@74201|Verrucomicrobia,3K7UI@414999|Opitutae	414999|Opitutae	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YHH3_k127_10557025_9	665956.HMPREF1032_02156	2.032e-51	192.0	COG0546@1|root,COG0546@2|Bacteria,1V7EI@1239|Firmicutes,24K0E@186801|Clostridia,3WPBF@541000|Ruminococcaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH3_k127_10557025_2	583355.Caka_1119	1.281e-155	518.0	COG0025@1|root,COG0569@1|root,COG1762@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	iJN678.sll0556	Na_H_Exchanger,PTS_EIIA_2,TrkA_N
YHH3_k127_10557025_1	583355.Caka_1567	3.126e-216	678.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,3K7DX@414999|Opitutae	414999|Opitutae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH3_k127_10557025_0	382464.ABSI01000011_gene2710	5.375e-242	759.0	COG0504@1|root,COG0504@2|Bacteria,46S8K@74201|Verrucomicrobia,2ITX8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
YHH3_k127_10557025_5	452637.Oter_0051	4.931e-108	358.0	COG2877@1|root,COG2877@2|Bacteria,46SMZ@74201|Verrucomicrobia,3K7E4@414999|Opitutae	414999|Opitutae	M	2-dehydro-3-deoxyphosphooctonate aldolase	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
YHH3_k127_10557025_10	1123009.AUID01000024_gene1419	5.012e-08	58.0	COG4872@1|root,COG4872@2|Bacteria,1V02I@1239|Firmicutes,24EE3@186801|Clostridia,26C38@186813|unclassified Clostridiales	186801|Clostridia	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
YHH3_k127_10557025_7	583355.Caka_1548	3.185e-101	340.0	COG3481@1|root,COG3481@2|Bacteria,46SYB@74201|Verrucomicrobia,3K78K@414999|Opitutae	414999|Opitutae	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD
YHH3_k127_10557025_11	1279009.ADICEAN_03438	0.0003463	53.0	COG4099@1|root,COG4733@1|root,COG4099@2|Bacteria,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PA14,fn3
YHH3_k127_10561529_2	240016.ABIZ01000001_gene5493	5.706e-17	81.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH3_k127_10561529_3	240016.ABIZ01000001_gene5493	2.09e-15	78.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH3_k127_10561529_4	240016.ABIZ01000001_gene5493	1.504e-11	66.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH3_k127_10561529_5	240016.ABIZ01000001_gene2150	1.659e-09	64.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH3_k127_10561529_1	283942.IL2412	5.789e-21	99.0	2ECBH@1|root,3369W@2|Bacteria,1NE1Q@1224|Proteobacteria,1SF6Y@1236|Gammaproteobacteria,2QG86@267893|Idiomarinaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10561529_0	583355.Caka_2163	3.459e-42	160.0	COG3449@1|root,COG3449@2|Bacteria	2|Bacteria	K	DNA topoisomerase (ATP-hydrolyzing) inhibitor activity	yhgE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	DUF4153,GyrI-like,SOUL
YHH3_k127_10578804_0	1121396.KB893053_gene2363	0.0	1014.0	COG4222@1|root,COG4222@2|Bacteria,1R2H4@1224|Proteobacteria	1224|Proteobacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
YHH3_k127_10584653_0	497964.CfE428DRAFT_2859	6.164e-28	133.0	28SQ5@1|root,2ZF09@2|Bacteria,46WN6@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10584653_1	1396141.BATP01000024_gene782	2.772e-05	57.0	COG3523@1|root,COG3523@2|Bacteria,46VI0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ImcF-related N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ImcF-related_N
YHH3_k127_10590102_6	756272.Plabr_4043	1.764e-24	121.0	COG3210@1|root,COG3210@2|Bacteria,2J27Z@203682|Planctomycetes	203682|Planctomycetes	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	PATR
YHH3_k127_10590102_4	530564.Psta_1830	4.628e-44	175.0	COG3515@1|root,COG3515@2|Bacteria,2J0E6@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion-associated protein, ImpA family	-	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N
YHH3_k127_10590102_2	497964.CfE428DRAFT_2834	3.094e-75	255.0	COG3516@1|root,COG3516@2|Bacteria,46VI5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VipA
YHH3_k127_10590102_0	765913.ThidrDRAFT_2282	8.183e-233	728.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,1WXN1@135613|Chromatiales	135613|Chromatiales	S	Type VI secretion protein, EvpB/VC_A0108, tail sheath	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
YHH3_k127_10590102_3	1120999.JONM01000005_gene3770	5.939e-46	171.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,2WEFR@28216|Betaproteobacteria,2KPCB@206351|Neisseriales	206351|Neisseriales	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
YHH3_k127_10590102_1	497964.CfE428DRAFT_2838	2.828e-75	262.0	COG4455@1|root,COG4455@2|Bacteria,46VF7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ImpE protein	-	-	-	-	-	-	-	-	-	-	-	-	ImpE
YHH3_k127_10590102_5	497964.CfE428DRAFT_2839	3.432e-36	144.0	COG3518@1|root,COG3518@2|Bacteria,46WW6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Gene 25-like lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	GPW_gp25
YHH3_k127_10591733_0	1396141.BATP01000034_gene4211	6.659e-17	95.0	COG2885@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3595@1|root,COG5276@1|root,COG2885@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.4.24.40	ko:K01406,ko:K15125	ko01503,ko05133,map01503,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000,ko01002	-	-	-	CHU_C,Haemagg_act,LVIVD
YHH3_k127_1060309_3	452637.Oter_3012	9.372e-88	299.0	COG0564@1|root,COG0564@2|Bacteria,46SQY@74201|Verrucomicrobia,3K7Y8@414999|Opitutae	414999|Opitutae	G	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
YHH3_k127_1060309_5	583355.Caka_1053	5.318e-75	258.0	COG1207@1|root,COG1207@2|Bacteria,46U38@74201|Verrucomicrobia,3K7X6@414999|Opitutae	414999|Opitutae	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YHH3_k127_1060309_6	240016.ABIZ01000001_gene1135	6.768e-53	192.0	COG1943@1|root,COG1943@2|Bacteria,46W84@74201|Verrucomicrobia,2IVXZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH3_k127_1060309_4	382464.ABSI01000013_gene1735	3.716e-76	263.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	hisN	-	3.1.3.15,3.1.3.25,3.1.3.93	ko:K01092,ko:K05602,ko:K18649	ko00053,ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00053,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00114,M00131	R01185,R01186,R01187,R03013,R07674	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YHH3_k127_1060309_1	794903.OPIT5_28335	1.205e-108	366.0	COG1109@1|root,COG1109@2|Bacteria,46SJ2@74201|Verrucomicrobia,3K7CB@414999|Opitutae	414999|Opitutae	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YHH3_k127_1060309_2	583355.Caka_2954	1.016e-98	336.0	COG0547@1|root,COG0547@2|Bacteria,46SQA@74201|Verrucomicrobia,3K7TG@414999|Opitutae	414999|Opitutae	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
YHH3_k127_1060309_0	518766.Rmar_2190	7.833e-213	671.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes,1FJ6T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41,1.1.1.42,1.1.1.85	ko:K00030,ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00709,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH3_k127_1060309_7	745014.OMB55_00013810	3.694e-45	169.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1J6HF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC-type oligopeptide transport system, periplasmic component	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
YHH3_k127_10615220_0	767817.Desgi_0611	8.524e-181	582.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia,2605J@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YHH3_k127_10615220_1	891968.Anamo_1655	3.201e-58	213.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,3TBAT@508458|Synergistetes	508458|Synergistetes	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
YHH3_k127_10643818_1	1121943.KB899991_gene2440	1.339e-48	178.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1XKKT@135619|Oceanospirillales	135619|Oceanospirillales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
YHH3_k127_10643818_0	314230.DSM3645_13780	2.708e-81	281.0	COG0657@1|root,COG0657@2|Bacteria,2IYY7@203682|Planctomycetes	203682|Planctomycetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
YHH3_k127_1065993_0	686340.Metal_2200	2.641e-48	190.0	2C6BE@1|root,32XBJ@2|Bacteria,1NB89@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10692770_3	1122179.KB890439_gene1644	2.746e-29	121.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA,ThuA,VCBS
YHH3_k127_10692770_0	452637.Oter_2669	1.024e-291	906.0	COG0129@1|root,COG0129@2|Bacteria,46UBB@74201|Verrucomicrobia	74201|Verrucomicrobia	EG	Dehydratase family	-	-	4.2.1.82	ko:K22396	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
YHH3_k127_10692770_4	484770.UFO1_3456	1.143e-15	81.0	COG0673@1|root,COG0673@2|Bacteria,1UZEK@1239|Firmicutes,4H77I@909932|Negativicutes	2|Bacteria	S	PFAM oxidoreductase domain protein, Oxidoreductase domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_10692770_1	929562.Emtol_2156	6.312e-94	315.0	COG1028@1|root,COG1028@2|Bacteria,4NF64@976|Bacteroidetes,47MEC@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH3_k127_10692770_2	1121904.ARBP01000011_gene1568	2.669e-59	212.0	COG1063@1|root,COG1063@2|Bacteria,4NJW8@976|Bacteroidetes,47M9A@768503|Cytophagia	976|Bacteroidetes	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_10695530_0	313624.NSP_23260	4.683e-117	383.0	COG0451@1|root,COG0451@2|Bacteria,1G457@1117|Cyanobacteria	1117|Cyanobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YHH3_k127_10695530_1	232346.JHQL01000003_gene102	1.826e-47	179.0	2DBVG@1|root,2ZBB1@2|Bacteria,1N1MS@1224|Proteobacteria,1SCGP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10708087_6	1268240.ATFI01000001_gene2737	4.037e-51	190.0	COG4977@1|root,COG4977@2|Bacteria,4P1XK@976|Bacteroidetes,2FMGD@200643|Bacteroidia,4AV21@815|Bacteroidaceae	976|Bacteroidetes	K	Transcriptional regulator, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
YHH3_k127_10708087_3	383372.Rcas_3455	1.205e-173	553.0	COG4806@1|root,COG4806@2|Bacteria,2GAHK@200795|Chloroflexi,37666@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the rhamnose isomerase family	rhaA	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
YHH3_k127_10708087_4	583355.Caka_2924	6.292e-147	469.0	COG1082@1|root,COG1082@2|Bacteria,46ZE0@74201|Verrucomicrobia,3K81E@414999|Opitutae	414999|Opitutae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_10708087_2	583355.Caka_2925	1.165e-176	559.0	COG0673@1|root,COG0673@2|Bacteria,46U3U@74201|Verrucomicrobia,3K7Y3@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_10708087_0	583355.Caka_2926	1.303e-257	802.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
YHH3_k127_10708087_5	583355.Caka_2927	7.734e-78	265.0	COG2133@1|root,COG3119@1|root,COG2133@2|Bacteria,COG3119@2|Bacteria,46Z7C@74201|Verrucomicrobia,3K9RA@414999|Opitutae	414999|Opitutae	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_10708087_1	382464.ABSI01000020_gene156	4.871e-195	614.0	COG0673@1|root,COG0673@2|Bacteria,46U2Q@74201|Verrucomicrobia,2IV92@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_10725997_1	1283283.ATXA01000005_gene2022	6.492e-25	123.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
YHH3_k127_10725997_0	314287.GB2207_03629	1.443e-79	271.0	COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,1RS8B@1236|Gammaproteobacteria,1J7S0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YHH3_k127_10725997_2	1403819.BATR01000118_gene4117	2.922e-23	100.0	COG0191@1|root,COG0191@2|Bacteria,46UMQ@74201|Verrucomicrobia,2ITR6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
YHH3_k127_10731495_1	1408473.JHXO01000011_gene3122	8.203e-84	280.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,2FND3@200643|Bacteroidia	976|Bacteroidetes	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
YHH3_k127_10731495_0	661367.LLO_2934	8.809e-94	321.0	COG3464@1|root,COG3464@2|Bacteria,1N2KA@1224|Proteobacteria,1RQVJ@1236|Gammaproteobacteria,1JGHT@118969|Legionellales	118969|Legionellales	L	to transposase (ISL3 family)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
YHH3_k127_10731495_3	1565314.OA34_08425	0.0006339	46.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2YMT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	RND efflux system, outer membrane lipoprotein	cmeC	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
YHH3_k127_10736771_3	1403819.BATR01000106_gene3649	2.08e-56	197.0	COG2755@1|root,COG2755@2|Bacteria,46V6J@74201|Verrucomicrobia,2IVPY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_10736771_2	313628.LNTAR_07224	7.686e-112	377.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
YHH3_k127_10736771_0	497964.CfE428DRAFT_0570	2.359e-182	586.0	COG1621@1|root,COG1621@2|Bacteria,46WGP@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
YHH3_k127_10736771_4	1408473.JHXO01000012_gene274	1.414e-25	120.0	COG1453@1|root,COG1453@2|Bacteria,4NGCW@976|Bacteroidetes,2FPG8@200643|Bacteroidia	976|Bacteroidetes	S	Tat pathway signal sequence domain protein	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
YHH3_k127_10736771_1	313628.LNTAR_11271	1.633e-112	379.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_1075516_3	1137281.D778_02055	4.009e-11	76.0	COG3227@1|root,COG3291@1|root,COG4935@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NQ5Q@976|Bacteroidetes	976|Bacteroidetes	E	Fungalysin/Thermolysin Propeptide Motif	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	FTP,PepSY,Peptidase_M36,Peptidase_M4
YHH3_k127_1075516_2	1408473.JHXO01000015_gene1897	2.011e-22	112.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
YHH3_k127_1075516_4	1121094.KB894644_gene2260	0.0001863	54.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,2FPU1@200643|Bacteroidia,4AKXT@815|Bacteroidaceae	976|Bacteroidetes	O	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Peptidase_S8_N,fn3
YHH3_k127_1075516_0	421531.IX38_14945	4.888e-73	252.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1HXZG@117743|Flavobacteriia,3ZPRG@59732|Chryseobacterium	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
YHH3_k127_1075516_1	45351.EDO26640	3.52e-43	160.0	COG0350@1|root,KOG4062@2759|Eukaryota	2759|Eukaryota	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity	atl1	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0032131,GO:0032132,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K07034,ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
YHH3_k127_10767139_8	1078020.KEK_19064	0.0002133	52.0	COG1073@1|root,COG1073@2|Bacteria,2GNB6@201174|Actinobacteria,2366C@1762|Mycobacteriaceae	201174|Actinobacteria	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
YHH3_k127_10767139_1	595460.RRSWK_01941	5.184e-180	576.0	COG3119@1|root,COG3119@2|Bacteria,2IXPB@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_10767139_2	1265503.KB905169_gene320	3.126e-96	323.0	COG0657@1|root,COG0657@2|Bacteria,1N5QB@1224|Proteobacteria,1RS7Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
YHH3_k127_10767139_3	1123070.KB899247_gene1477	1.752e-45	174.0	2DJ7R@1|root,31A93@2|Bacteria,46WV4@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10767139_7	313628.LNTAR_10991	2.57e-06	50.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_10767139_6	1379270.AUXF01000007_gene948	1.341e-13	77.0	290AB@1|root,2ZMZX@2|Bacteria,1ZUWH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cytochrome b562	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B562
YHH3_k127_10767139_4	1434325.AZQN01000005_gene3514	2.874e-40	159.0	COG4886@1|root,COG4886@2|Bacteria,4NFES@976|Bacteroidetes,47MG0@768503|Cytophagia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,PSCyt1
YHH3_k127_10767139_0	756272.Plabr_3928	6.673e-223	702.0	COG3119@1|root,COG3119@2|Bacteria,2J20N@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_10767139_5	616991.JPOO01000003_gene1578	6.388e-40	152.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1HZWB@117743|Flavobacteriia,23G8X@178469|Arenibacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_10784174_2	1121374.KB891586_gene2542	4.653e-171	554.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
YHH3_k127_10784174_1	1403819.BATR01000191_gene6474	2.693e-174	551.0	COG2115@1|root,COG2115@2|Bacteria	2|Bacteria	G	xylose isomerase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH3_k127_10784174_5	1403819.BATR01000191_gene6477	5.927e-86	295.0	COG0524@1|root,COG0524@2|Bacteria,46SCP@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH3_k127_10784174_3	794903.OPIT5_22695	8.707e-147	473.0	COG1830@1|root,COG1830@2|Bacteria,46XHW@74201|Verrucomicrobia,3K7BX@414999|Opitutae	414999|Opitutae	G	Aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10784174_6	382464.ABSI01000011_gene2801	5.277e-79	272.0	COG1028@1|root,COG1028@2|Bacteria,46XQD@74201|Verrucomicrobia,2IWD8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH3_k127_10784174_0	1218075.BAYA01000059_gene7024	8.577e-188	600.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2VHTR@28216|Betaproteobacteria,1K3XY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM deoxyribodipyrimidine photolyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
YHH3_k127_10784174_4	1205680.CAKO01000010_gene3712	1.265e-88	304.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,2JR8C@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_10784174_7	497964.CfE428DRAFT_3853	4.87e-40	152.0	COG0607@1|root,COG0607@2|Bacteria,46VNB@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH3_k127_10804659_0	710685.MycrhN_2535	9.821e-270	863.0	COG2274@1|root,COG2274@2|Bacteria,2GNB5@201174|Actinobacteria,238WK@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
YHH3_k127_10804659_1	555779.Dthio_PD1532	4.21e-09	60.0	COG1943@1|root,COG1943@2|Bacteria,1RBFM@1224|Proteobacteria,42QPI@68525|delta/epsilon subdivisions,2WMUC@28221|Deltaproteobacteria,2MEYV@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH3_k127_10805821_2	926569.ANT_14450	3.937e-106	347.0	COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
YHH3_k127_10805821_1	768710.DesyoDRAFT_1295	2.007e-137	450.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,26000@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
YHH3_k127_10805821_0	459349.CLOAM1631	2.98e-174	556.0	COG0167@1|root,COG0493@1|root,COG1148@1|root,COG0167@2|Bacteria,COG0493@2|Bacteria,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	pds	-	1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9	ko:K00207,ko:K00219,ko:K00317,ko:K02293,ko:K10797,ko:K12527,ko:K17723	ko00240,ko00360,ko00410,ko00450,ko00680,ko00770,ko00906,ko00983,ko01100,ko01110,ko01120,ko01200,map00240,map00360,map00410,map00450,map00680,map00770,map00906,map00983,map01100,map01110,map01120,map01200	M00046,M00097	R00977,R00978,R01414,R01415,R01588,R02252,R02511,R04786,R04787,R07229,R07510,R08226,R09652,R09653,R09654,R11026	RC00072,RC00123,RC00185,RC00556,RC00557,RC00669,RC00732,RC01214,RC01958,RC02245,RC02420,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Fer4,Fer4_4,Pyr_redox_2
YHH3_k127_10852551_4	1396141.BATP01000025_gene972	1.108e-122	396.0	COG2407@1|root,COG2407@2|Bacteria,46ZAF@74201|Verrucomicrobia,2ITQK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
YHH3_k127_10852551_8	1396141.BATP01000025_gene973	1.371e-50	190.0	COG2207@1|root,COG2207@2|Bacteria,46VFS@74201|Verrucomicrobia,2IVVR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
YHH3_k127_10852551_1	756272.Plabr_3754	1.204e-207	659.0	COG3119@1|root,COG3119@2|Bacteria,2J1WG@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_10852551_0	1168034.FH5T_02545	1.774e-304	944.0	COG3250@1|root,COG3250@2|Bacteria,4NFPC@976|Bacteroidetes,2FPUZ@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_10852551_5	1550091.JROE01000004_gene1456	9.694e-113	376.0	COG0613@1|root,COG0613@2|Bacteria,4NHZ5@976|Bacteroidetes,1ISEJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001
YHH3_k127_10852551_2	869213.JCM21142_114597	1.824e-198	632.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
YHH3_k127_10852551_3	1168034.FH5T_18780	3.746e-180	575.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,2FQ3G@200643|Bacteroidia	976|Bacteroidetes	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
YHH3_k127_10852551_6	573413.Spirs_1202	1.594e-110	379.0	COG3525@1|root,COG3525@2|Bacteria,2J6RZ@203691|Spirochaetes	203691|Spirochaetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
YHH3_k127_10852551_7	452637.Oter_1484	9.667e-52	195.0	COG0679@1|root,COG0679@2|Bacteria,46VZ1@74201|Verrucomicrobia,3K82I@414999|Opitutae	414999|Opitutae	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
YHH3_k127_10852551_9	550540.Fbal_0050	3.718e-50	185.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
YHH3_k127_10854510_6	391625.PPSIR1_36222	3.259e-05	46.0	COG2382@1|root,COG2382@2|Bacteria,1QWH3@1224|Proteobacteria	1224|Proteobacteria	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YHH3_k127_10854510_3	1407650.BAUB01000003_gene754	5.968e-31	123.0	COG3369@1|root,COG3369@2|Bacteria,1G7ZE@1117|Cyanobacteria,1H4B8@1129|Synechococcus	1117|Cyanobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
YHH3_k127_10854510_2	497964.CfE428DRAFT_2620	1.873e-108	357.0	COG0330@1|root,COG0330@2|Bacteria,46VDU@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH3_k127_10854510_1	497964.CfE428DRAFT_2621	8.57e-135	441.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
YHH3_k127_10854510_4	652103.Rpdx1_0934	2.103e-29	123.0	COG3304@1|root,COG3304@2|Bacteria,1RA96@1224|Proteobacteria,2U742@28211|Alphaproteobacteria,3JYSW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Inner membrane component domain	MA20_16325	-	-	-	-	-	-	-	-	-	-	-	YccF
YHH3_k127_10854510_0	756272.Plabr_3146	1.053e-240	758.0	COG5492@1|root,COG5492@2|Bacteria,2IYV9@203682|Planctomycetes	203682|Planctomycetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
YHH3_k127_10854510_5	1123242.JH636435_gene2614	6.536e-07	54.0	COG3119@1|root,COG3119@2|Bacteria,2IWVY@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_10869575_2	1161401.ASJA01000009_gene1787	1.33e-23	102.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,2URZH@28211|Alphaproteobacteria,43XR7@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
YHH3_k127_10869575_1	761193.Runsl_4745	1.206e-75	266.0	COG0449@1|root,COG0449@2|Bacteria,4NK32@976|Bacteroidetes,47M7K@768503|Cytophagia	976|Bacteroidetes	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	-
YHH3_k127_10869575_0	1191523.MROS_0509	7.406e-187	597.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_10881506_1	1321778.HMPREF1982_02111	3.11e-89	298.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,268E7@186813|unclassified Clostridiales	186801|Clostridia	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdh	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YHH3_k127_10881506_0	382464.ABSI01000011_gene2618	1.76e-101	336.0	COG0668@1|root,COG0668@2|Bacteria,46V1Y@74201|Verrucomicrobia,2IUI5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
YHH3_k127_10881506_3	452637.Oter_0842	1.498e-71	254.0	COG3137@1|root,COG3137@2|Bacteria,46TU0@74201|Verrucomicrobia,3K75A@414999|Opitutae	414999|Opitutae	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
YHH3_k127_10881506_2	926550.CLDAP_30450	2.579e-82	289.0	COG0607@1|root,COG0659@1|root,COG0607@2|Bacteria,COG0659@2|Bacteria,2G83D@200795|Chloroflexi	200795|Chloroflexi	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Rhodanese,STAS,Sulfate_transp
YHH3_k127_10888961_4	1303692.SFUL_4715	9.533e-67	236.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde dehydrogenase	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH3_k127_10888961_0	1121104.AQXH01000001_gene1194	3.594e-206	651.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1INYZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH3_k127_10888961_2	1121930.AQXG01000001_gene1487	2.375e-108	358.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
YHH3_k127_10888961_1	382464.ABSI01000011_gene2906	7.827e-123	402.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH3_k127_10888961_3	382464.ABSI01000011_gene2907	6.64e-67	236.0	COG1842@1|root,COG1842@2|Bacteria	2|Bacteria	KT	Phage shock protein A	pspA	GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141	-	ko:K03969	-	-	-	-	ko00000	-	-	-	LRAT,PspA_IM30
YHH3_k127_10901474_4	314266.SKA58_08120	1.611e-17	91.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,2U9FW@28211|Alphaproteobacteria,2K4F5@204457|Sphingomonadales	204457|Sphingomonadales	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
YHH3_k127_10901474_1	395493.BegalDRAFT_3550	6.979e-95	323.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,462QK@72273|Thiotrichales	72273|Thiotrichales	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YHH3_k127_10901474_3	583355.Caka_1979	3.902e-51	207.0	COG3525@1|root,COG3525@2|Bacteria,46WQ6@74201|Verrucomicrobia,3KA1V@414999|Opitutae	414999|Opitutae	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
YHH3_k127_10901474_0	382464.ABSI01000012_gene1959	4.626e-175	569.0	COG1086@1|root,COG1086@2|Bacteria,46UPP@74201|Verrucomicrobia,2IVCB@203494|Verrucomicrobiae	2|Bacteria	GM	Polysaccharide biosynthesis protein	capD	GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192	4.2.1.115,4.2.1.135,4.2.1.46	ko:K01710,ko:K15894,ko:K15912,ko:K19421	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R06513,R09697	RC00402,RC02609	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
YHH3_k127_10901474_2	981383.AEWH01000061_gene2359	1.068e-57	215.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli	91061|Bacilli	M	transferase	tagO	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
YHH3_k127_10901474_5	1229204.AMYY01000029_gene809	3.301e-08	65.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U2E5@28211|Alphaproteobacteria,4BSH9@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH3_k127_10904664_1	909663.KI867150_gene76	1.776e-25	119.0	COG1404@1|root,COG1404@2|Bacteria,1PFBD@1224|Proteobacteria,43A1G@68525|delta/epsilon subdivisions,2X9U2@28221|Deltaproteobacteria,2MSGE@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH3_k127_10904664_0	335543.Sfum_3603	6.393e-32	126.0	2AWFD@1|root,31NBM@2|Bacteria,1QK2M@1224|Proteobacteria,4334D@68525|delta/epsilon subdivisions,2WY8Q@28221|Deltaproteobacteria,2MSA1@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
YHH3_k127_10932022_2	394221.Mmar10_2646	1.573e-71	248.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,43Z82@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YHH3_k127_10932022_4	1233951.IO90_09890	4.963e-34	138.0	COG2068@1|root,COG2068@2|Bacteria,4NQNF@976|Bacteroidetes,1I2S6@117743|Flavobacteriia,3HJ05@358033|Chryseobacterium	976|Bacteroidetes	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
YHH3_k127_10932022_3	1396141.BATP01000043_gene1941	6.068e-53	198.0	COG1975@1|root,COG1975@2|Bacteria,46W0F@74201|Verrucomicrobia,2IW06@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
YHH3_k127_10932022_1	744872.Spica_2277	6.058e-94	318.0	COG0667@1|root,COG0667@2|Bacteria,2JBJ9@203691|Spirochaetes	203691|Spirochaetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_10932022_0	616991.JPOO01000001_gene4135	3.037e-222	695.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,1HZCK@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_10936448_2	383372.Rcas_1611	5.434e-46	173.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
YHH3_k127_10936448_1	1047013.AQSP01000144_gene852	1.811e-61	221.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH3_k127_10936448_0	1122605.KB893649_gene3750	4.84e-134	441.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1IS5G@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Laminin_G_3,Sulfatase
YHH3_k127_10938331_1	1283300.ATXB01000001_gene901	1.238e-70	254.0	COG1404@1|root,COG2931@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4935@2|Bacteria,1MU7T@1224|Proteobacteria,1T2VQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OQ	serine protease	avxIA	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind,P_proprotein,Peptidase_S8
YHH3_k127_10938331_0	583355.Caka_1379	4.32e-163	522.0	COG1055@1|root,COG1055@2|Bacteria,46S61@74201|Verrucomicrobia,3K7MJ@414999|Opitutae	414999|Opitutae	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
YHH3_k127_10940400_7	452637.Oter_1912	6.509e-32	126.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia,3K8AZ@414999|Opitutae	414999|Opitutae	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
YHH3_k127_10940400_5	1408473.JHXO01000011_gene3149	2.923e-49	182.0	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,2FNYZ@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH3_k127_10940400_10	583355.Caka_2472	1.937e-11	64.0	COG0230@1|root,COG0230@2|Bacteria,46XWC@74201|Verrucomicrobia,3K8GI@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
YHH3_k127_10940400_9	583355.Caka_2473	2.892e-14	77.0	COG0594@1|root,COG0594@2|Bacteria,46WMC@74201|Verrucomicrobia,3K8HX@414999|Opitutae	414999|Opitutae	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
YHH3_k127_10940400_8	1150600.ADIARSV_1735	1.617e-23	104.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1ITUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
YHH3_k127_10940400_1	382464.ABSI01000013_gene1506	7.033e-122	413.0	COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia,2ITX0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
YHH3_k127_10940400_4	583355.Caka_2476	9.79e-100	331.0	COG0217@1|root,COG0217@2|Bacteria,46SP3@74201|Verrucomicrobia,3K74P@414999|Opitutae	414999|Opitutae	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
YHH3_k127_10940400_0	583355.Caka_1589	5.46e-153	492.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia,3K8UM@414999|Opitutae	414999|Opitutae	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH3_k127_10940400_6	765914.ThisiDRAFT_1954	1.164e-37	153.0	COG0642@1|root,COG2205@2|Bacteria,1RF79@1224|Proteobacteria,1SNRK@1236|Gammaproteobacteria,1X0NK@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YHH3_k127_10940400_2	583355.Caka_1147	1.557e-113	374.0	COG0152@1|root,COG0152@2|Bacteria,46SIP@74201|Verrucomicrobia,3K7AD@414999|Opitutae	414999|Opitutae	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
YHH3_k127_10940400_3	272562.CA_C0626	1.117e-112	373.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,36DNK@31979|Clostridiaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH3_k127_10940400_11	1121949.AQXT01000002_gene917	6.957e-08	63.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2TRMU@28211|Alphaproteobacteria,43WX6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
YHH3_k127_10977043_3	517418.Ctha_0216	7.518e-21	97.0	2E6U3@1|root,331DV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
YHH3_k127_10977043_0	382464.ABSI01000020_gene317	9.122e-79	272.0	COG1237@1|root,COG1237@2|Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
YHH3_k127_10977043_1	1283300.ATXB01000001_gene434	1.444e-26	120.0	COG3640@1|root,COG3640@2|Bacteria,1RB02@1224|Proteobacteria,1SGMS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
YHH3_k127_10995666_1	583355.Caka_2391	5.048e-87	301.0	COG0795@1|root,COG0795@2|Bacteria,46STR@74201|Verrucomicrobia,3K762@414999|Opitutae	414999|Opitutae	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
YHH3_k127_10995666_0	583355.Caka_1644	8.868e-131	428.0	COG1168@1|root,COG1168@2|Bacteria,46TPH@74201|Verrucomicrobia,3K7N9@414999|Opitutae	414999|Opitutae	E	Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_10999289_8	382464.ABSI01000010_gene3686	3.989e-92	309.0	COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,2ITQ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
YHH3_k127_10999289_7	583355.Caka_1793	1.329e-107	358.0	COG0618@1|root,COG0618@2|Bacteria,46T03@74201|Verrucomicrobia,3K7K6@414999|Opitutae	414999|Opitutae	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH3_k127_10999289_11	382464.ABSI01000010_gene3688	8.752e-21	96.0	COG0858@1|root,COG0858@2|Bacteria,46TBI@74201|Verrucomicrobia,2IUMI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
YHH3_k127_10999289_1	583355.Caka_1795	1.679e-247	788.0	COG0532@1|root,COG0532@2|Bacteria,46S8V@74201|Verrucomicrobia,3K79C@414999|Opitutae	414999|Opitutae	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
YHH3_k127_10999289_4	583355.Caka_1796	3.726e-179	576.0	COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia,3K7UP@414999|Opitutae	414999|Opitutae	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
YHH3_k127_10999289_10	382464.ABSI01000010_gene3691	1.081e-52	202.0	28HQ3@1|root,2Z7XW@2|Bacteria,46U81@74201|Verrucomicrobia,2ITXI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
YHH3_k127_10999289_13	1221537.B807_1205	0.0002157	50.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,3F5KC@33958|Lactobacillaceae	91061|Bacilli	S	YacP-like NYN domain	yacP	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
YHH3_k127_10999289_3	382464.ABSI01000005_gene1070	8.779e-198	631.0	COG1227@1|root,COG4109@1|root,COG1227@2|Bacteria,COG4109@2|Bacteria,46UKX@74201|Verrucomicrobia,2ITG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	DHHA2	-	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
YHH3_k127_10999289_2	382464.ABSI01000023_gene546	5.548e-246	780.0	COG0557@1|root,COG0557@2|Bacteria,46U8T@74201|Verrucomicrobia,2ITHQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
YHH3_k127_10999289_0	794903.OPIT5_18285	0.0	1042.0	COG0567@1|root,COG0567@2|Bacteria,46S6G@74201|Verrucomicrobia,3K743@414999|Opitutae	414999|Opitutae	C	2-oxoglutarate dehydrogenase C-terminal	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
YHH3_k127_10999289_6	382464.ABSI01000005_gene1108	4.74e-146	472.0	COG0508@1|root,COG0508@2|Bacteria,46SD3@74201|Verrucomicrobia,2ITTQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl
YHH3_k127_10999289_5	382464.ABSI01000005_gene1107	4.966e-165	531.0	COG1249@1|root,COG1249@2|Bacteria,46S7E@74201|Verrucomicrobia,2ITM3@203494|Verrucomicrobiae	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iE2348C_1286.E2348C_4372,iJN746.PP_4187	Pyr_redox_2,Pyr_redox_dim
YHH3_k127_10999289_12	382464.ABSI01000011_gene3063	1.341e-13	75.0	COG5512@1|root,COG5512@2|Bacteria,46WT9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
YHH3_k127_10999289_9	583355.Caka_1443	8.409e-75	256.0	COG1235@1|root,COG1235@2|Bacteria,46SRW@74201|Verrucomicrobia,3K7PE@414999|Opitutae	414999|Opitutae	S	Beta-lactamase superfamily domain	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
YHH3_k127_11031737_5	382464.ABSI01000020_gene173	6.585e-05	52.0	COG3156@1|root,COG3156@2|Bacteria,46VZT@74201|Verrucomicrobia,2IUG2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
YHH3_k127_11031737_1	583355.Caka_1640	9.378e-28	127.0	COG4972@1|root,COG4972@2|Bacteria,46WVK@74201|Verrucomicrobia,3K8A8@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11031737_3	583355.Caka_1641	9.698e-18	90.0	2BMCF@1|root,32FWN@2|Bacteria,46XUN@74201|Verrucomicrobia,3K8A6@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	T2SSM_b
YHH3_k127_11031737_0	583355.Caka_1642	4.419e-125	428.0	COG1450@1|root,COG1450@2|Bacteria,46UJF@74201|Verrucomicrobia,3K7CH@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
YHH3_k127_11031737_2	583355.Caka_2674	1.657e-21	103.0	COG2804@1|root,COG2804@2|Bacteria,46UIY@74201|Verrucomicrobia,3K7E3@414999|Opitutae	414999|Opitutae	NU	Secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
YHH3_k127_11034514_2	794903.OPIT5_03020	1.87e-40	155.0	COG0009@1|root,COG0009@2|Bacteria,46UW5@74201|Verrucomicrobia,3K7I8@414999|Opitutae	414999|Opitutae	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
YHH3_k127_11034514_3	583355.Caka_2439	2.516e-13	74.0	COG0238@1|root,COG0238@2|Bacteria,46ZDM@74201|Verrucomicrobia,3K8HR@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bS18 family	-	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
YHH3_k127_11034514_1	583355.Caka_1129	1.04e-76	269.0	2A75V@1|root,30W1Q@2|Bacteria,46YTX@74201|Verrucomicrobia,3K77H@414999|Opitutae	414999|Opitutae	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
YHH3_k127_11034514_0	497964.CfE428DRAFT_0835	1.444e-181	575.0	COG0297@1|root,COG0297@2|Bacteria,46Z3D@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_11050159_0	583355.Caka_1712	2.486e-221	698.0	COG1132@1|root,COG1132@2|Bacteria,46YXP@74201|Verrucomicrobia,3K7FZ@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH3_k127_11050159_1	583355.Caka_1134	2.121e-19	90.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,46U4X@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
YHH3_k127_11072489_5	382464.ABSI01000021_gene421	1.482e-52	186.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia,2IUGB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Nitrogen regulatory protein P-II	-	-	-	-	-	-	-	-	-	-	-	-	P-II
YHH3_k127_11072489_1	382464.ABSI01000021_gene420	6.94e-174	557.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,2ITWC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ammonium Transporter Family	-	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
YHH3_k127_11072489_0	382464.ABSI01000021_gene419	1.012e-271	846.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,2ITZA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
YHH3_k127_11072489_6	519989.ECTPHS_09672	6.176e-39	152.0	COG0500@1|root,COG2226@2|Bacteria,1QWR5@1224|Proteobacteria,1T2WY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	rRNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
YHH3_k127_11072489_4	382464.ABSI01000010_gene3558	1.849e-75	271.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH3_k127_11072489_2	382464.ABSI01000010_gene3557	5.508e-104	346.0	COG4152@1|root,COG4152@2|Bacteria	2|Bacteria	S	ATPase activity	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YHH3_k127_11072489_3	331869.BAL199_15968	5.141e-89	301.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2TQQ5@28211|Alphaproteobacteria,4BPDU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Serine acetyltransferase, N-terminal	cysE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
YHH3_k127_1108104_2	1433126.BN938_2104	1.154e-80	280.0	COG1242@1|root,COG1242@2|Bacteria,4NGK6@976|Bacteroidetes,2FPR8@200643|Bacteroidia,22U4X@171550|Rikenellaceae	976|Bacteroidetes	S	Radical SAM protein	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
YHH3_k127_1108104_1	583355.Caka_2820	1.132e-131	438.0	COG0513@1|root,COG0513@2|Bacteria	2|Bacteria	L	helicase activity	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
YHH3_k127_1108104_0	886293.Sinac_6998	2.154e-140	462.0	COG3250@1|root,COG3250@2|Bacteria,2J54D@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
YHH3_k127_1108104_3	1379858.N508_00435	7.297e-44	166.0	COG1272@1|root,COG1272@2|Bacteria,2GFPI@200930|Deferribacteres	200930|Deferribacteres	S	channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
YHH3_k127_11094690_13	314230.DSM3645_11417	1.145e-84	290.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,2IXKV@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,NPCBM,ThuA
YHH3_k127_11094690_17	572477.Alvin_1172	5.46e-16	91.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1141@1|root,COG1144@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1141@2|Bacteria,COG1144@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1WX9H@135613|Chromatiales	135613|Chromatiales	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH3_k127_11094690_14	1049564.TevJSym_bb00040	2.708e-81	281.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
YHH3_k127_11094690_1	1049564.TevJSym_bb00050	5.68e-198	636.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
YHH3_k127_11094690_9	382464.ABSI01000013_gene1833	1.547e-112	376.0	COG2942@1|root,COG2942@2|Bacteria,46U8G@74201|Verrucomicrobia,2IWMQ@203494|Verrucomicrobiae	74201|Verrucomicrobia	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
YHH3_k127_11094690_3	935845.JADQ01000050_gene3903	2.339e-179	568.0	COG2152@1|root,COG2152@2|Bacteria,1TNYI@1239|Firmicutes,4HA02@91061|Bacilli,26QPI@186822|Paenibacillaceae	91061|Bacilli	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	unk1	-	2.4.1.281	ko:K16212	-	-	R09943	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
YHH3_k127_11094690_16	869213.JCM21142_93856	1.093e-63	231.0	COG2730@1|root,COG4733@1|root,COG5492@1|root,COG2730@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,4P0E7@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11094690_18	452637.Oter_2315	5.211e-07	57.0	COG2211@1|root,COG2211@2|Bacteria,46UFW@74201|Verrucomicrobia	74201|Verrucomicrobia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
YHH3_k127_11094690_10	1168034.FH5T_22070	3.069e-104	350.0	COG2730@1|root,COG2730@2|Bacteria,4NGAC@976|Bacteroidetes,2G2RW@200643|Bacteroidia	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
YHH3_k127_11094690_7	382464.ABSI01000007_gene4070	3.164e-151	484.0	COG2152@1|root,COG2152@2|Bacteria,46S8T@74201|Verrucomicrobia,2IUQX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
YHH3_k127_11094690_8	382464.ABSI01000013_gene1834	6.468e-115	383.0	COG1609@1|root,COG2207@1|root,COG1609@2|Bacteria,COG2207@2|Bacteria,46TR8@74201|Verrucomicrobia,2IU7X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Peripla_BP_3
YHH3_k127_11094690_4	583355.Caka_2991	2.185e-176	557.0	COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,3K77U@414999|Opitutae	414999|Opitutae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
YHH3_k127_11094690_2	583355.Caka_2992	2.223e-182	579.0	COG0126@1|root,COG0126@2|Bacteria,46SI9@74201|Verrucomicrobia,3K76C@414999|Opitutae	414999|Opitutae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
YHH3_k127_11094690_11	452637.Oter_3825	1.069e-101	337.0	COG0149@1|root,COG0149@2|Bacteria,46SNB@74201|Verrucomicrobia,3K7RD@414999|Opitutae	414999|Opitutae	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
YHH3_k127_11094690_5	572544.Ilyop_0632	1.291e-163	537.0	COG1164@1|root,COG1164@2|Bacteria,378MH@32066|Fusobacteria	32066|Fusobacteria	E	Psort location Cytoplasmic, score	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YHH3_k127_11094690_0	335543.Sfum_2336	1.832e-282	874.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,43DIW@68525|delta/epsilon subdivisions,2X8Q7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
YHH3_k127_11094690_6	452637.Oter_3572	6.575e-154	512.0	COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia,3K7JM@414999|Opitutae	414999|Opitutae	M	Mur ligase	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH3_k127_11094690_12	794903.OPIT5_22950	7.071e-88	298.0	COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia,3K768@414999|Opitutae	414999|Opitutae	L	UreE urease accessory protein, C-terminal domain	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH3_k127_11094690_15	330214.NIDE1873	1.784e-79	289.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF748,OmpA
YHH3_k127_11104375_1	452637.Oter_2009	1.044e-208	661.0	COG0326@1|root,COG0326@2|Bacteria,46U76@74201|Verrucomicrobia,3K7PC@414999|Opitutae	414999|Opitutae	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
YHH3_k127_11104375_0	452637.Oter_3092	1.221e-271	852.0	COG0855@1|root,COG0855@2|Bacteria,46SB4@74201|Verrucomicrobia,3K74J@414999|Opitutae	414999|Opitutae	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
YHH3_k127_11113715_1	1121904.ARBP01000003_gene6151	1.576e-37	147.0	28KJN@1|root,2ZA4P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11113715_2	1122179.KB890439_gene1645	2.326e-06	51.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
YHH3_k127_11113715_0	382464.ABSI01000011_gene2465	3.441e-62	230.0	COG2273@1|root,COG3291@1|root,COG5297@1|root,COG2273@2|Bacteria,COG3291@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CBM_4_9,CBM_6,Glyco_hydro_16,Laminin_G_3,PKD
YHH3_k127_11113715_3	1122179.KB890439_gene1644	1.448e-05	49.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA,ThuA,VCBS
YHH3_k127_11148124_0	926550.CLDAP_08980	1.759e-118	384.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
YHH3_k127_11148124_2	1317124.DW2_10749	1.733e-57	209.0	COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,2U27Q@28211|Alphaproteobacteria,2XMQ2@285107|Thioclava	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH3_k127_11148124_1	1209072.ALBT01000077_gene427	5.327e-60	213.0	2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,1S78C@1236|Gammaproteobacteria,1FIF6@10|Cellvibrio	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3833)	PP2730	-	-	-	-	-	-	-	-	-	-	-	DUF3833
YHH3_k127_11148124_3	331869.BAL199_02454	3.943e-18	90.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2U1DI@28211|Alphaproteobacteria,4BS5X@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
YHH3_k127_11152686_2	1249997.JHZW01000002_gene377	4.826e-49	184.0	COG1680@1|root,COG1680@2|Bacteria,4PI6J@976|Bacteroidetes,1IGEU@117743|Flavobacteriia,2PIUV@252356|Maribacter	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH3_k127_11152686_0	589865.DaAHT2_2426	2.182e-108	359.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,42M30@68525|delta/epsilon subdivisions,2WKRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
YHH3_k127_11152686_1	1385935.N836_31165	3.383e-89	302.0	COG4912@1|root,COG4912@2|Bacteria,1G63N@1117|Cyanobacteria,1HFFN@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YHH3_k127_11224664_1	373994.Riv7116_1436	1.649e-61	225.0	COG1165@1|root,COG1165@2|Bacteria,1G1FW@1117|Cyanobacteria,1HK50@1161|Nostocales	1117|Cyanobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
YHH3_k127_11224664_0	583355.Caka_0851	1.678e-145	465.0	COG0447@1|root,COG0447@2|Bacteria,46U86@74201|Verrucomicrobia,3K790@414999|Opitutae	414999|Opitutae	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YHH3_k127_11224664_3	382464.ABSI01000010_gene3446	2.055e-07	58.0	COG0496@1|root,COG0496@2|Bacteria,46VWU@74201|Verrucomicrobia,2IWCV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Survival protein SurE	-	-	-	-	-	-	-	-	-	-	-	-	SurE
YHH3_k127_1122788_1	926569.ANT_20630	4.521e-47	182.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
YHH3_k127_1122788_0	926569.ANT_11580	8.625e-109	360.0	COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
YHH3_k127_11262823_5	452637.Oter_0600	3.963e-49	200.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_11262823_7	143224.JQMD01000002_gene174	3.77e-06	49.0	COG3940@1|root,COG3940@2|Bacteria,4NQXR@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
YHH3_k127_11262823_1	1121904.ARBP01000027_gene732	8.778e-151	490.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47M69@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_11262823_0	1121904.ARBP01000027_gene744	1.122e-208	660.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47ND1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_11262823_6	1392498.JQLH01000001_gene2750	3.898e-13	83.0	COG5434@1|root,COG5434@2|Bacteria,4NICS@976|Bacteroidetes,1I05A@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
YHH3_k127_11262823_4	1121904.ARBP01000027_gene732	2.316e-134	445.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47M69@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_11262823_2	1328313.DS2_10988	1.192e-146	489.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11262823_3	880073.Calab_0031	2.431e-135	439.0	COG2017@1|root,COG2017@2|Bacteria,2NQA5@2323|unclassified Bacteria	2|Bacteria	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
YHH3_k127_11264140_1	483215.BACFIN_05608	6.658e-06	50.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,2FQ3G@200643|Bacteroidia,4ANW6@815|Bacteroidaceae	976|Bacteroidetes	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
YHH3_k127_11264140_0	398512.JQKC01000076_gene2704	3.909e-43	177.0	COG5184@1|root,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,2486M@186801|Clostridia,3WM05@541000|Ruminococcaceae	186801|Clostridia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2
YHH3_k127_11277427_2	216595.PFLU_0131	1.69e-50	197.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,1YQ4R@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
YHH3_k127_11277427_0	686340.Metal_0969	2.353e-116	385.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,1XEK4@135618|Methylococcales	135618|Methylococcales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH3_k127_11277427_1	1444711.CCJF01000005_gene551	1.3e-57	205.0	COG0842@1|root,COG0842@2|Bacteria,2JFXH@204428|Chlamydiae	204428|Chlamydiae	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH3_k127_11302834_1	1121904.ARBP01000004_gene783	2.413e-43	160.0	COG1878@1|root,COG1878@2|Bacteria,4NFYB@976|Bacteroidetes,47XKZ@768503|Cytophagia	976|Bacteroidetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YHH3_k127_11302834_0	143224.JQMD01000002_gene3082	3.575e-148	480.0	COG2271@1|root,COG2271@2|Bacteria,4NGCR@976|Bacteroidetes,1HWZ4@117743|Flavobacteriia	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH3_k127_11302834_2	504487.JCM19302_3589	2.173e-20	92.0	COG0673@1|root,COG0673@2|Bacteria,4NJEP@976|Bacteroidetes,1I3KI@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_11322181_2	936589.HMPREF1521_1014	7.551e-72	247.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H2KR@909932|Negativicutes	909932|Negativicutes	E	LAO AO transport system	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
YHH3_k127_11322181_1	338963.Pcar_0306	4.949e-93	312.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42PH4@68525|delta/epsilon subdivisions,2WME5@28221|Deltaproteobacteria,43T1N@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Conserved TM helix	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
YHH3_k127_11322181_0	1242864.D187_009279	7.208e-229	725.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2YX1T@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
YHH3_k127_11324590_2	880526.KE386488_gene1316	2.224e-19	93.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia,22UKP@171550|Rikenellaceae	976|Bacteroidetes	S	NPCBM/NEW2 domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NPCBM
YHH3_k127_11324590_1	314230.DSM3645_13780	2.452e-31	142.0	COG0657@1|root,COG0657@2|Bacteria,2IYY7@203682|Planctomycetes	203682|Planctomycetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
YHH3_k127_11324590_0	497964.CfE428DRAFT_2331	7.586e-43	179.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Esterase
YHH3_k127_11380633_4	344747.PM8797T_03084	3.67e-63	224.0	COG2010@1|root,COG2133@1|root,COG3502@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3502@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
YHH3_k127_11380633_0	583355.Caka_0543	3.945e-192	606.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	yegT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	Nuc_H_symport
YHH3_k127_11380633_3	583355.Caka_0544	5.081e-99	329.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
YHH3_k127_11380633_2	583355.Caka_0545	1.385e-107	358.0	COG0673@1|root,COG0673@2|Bacteria,46UTE@74201|Verrucomicrobia,3K8EQ@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_11380633_1	583355.Caka_0546	5.297e-188	596.0	COG0673@1|root,COG0673@2|Bacteria,46U5R@74201|Verrucomicrobia,3K8ZI@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_11405886_2	1192034.CAP_6452	9.793e-53	188.0	COG1196@1|root,COG1196@2|Bacteria,1RJS1@1224|Proteobacteria,43236@68525|delta/epsilon subdivisions,2WWXG@28221|Deltaproteobacteria,2YV0I@29|Myxococcales	28221|Deltaproteobacteria	D	Domain of unknown function (DUF4150)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150
YHH3_k127_11405886_1	1254432.SCE1572_30535	7.763e-85	293.0	COG0304@1|root,COG0304@2|Bacteria,1R618@1224|Proteobacteria,439FX@68525|delta/epsilon subdivisions,2X4RQ@28221|Deltaproteobacteria,2YZG9@29|Myxococcales	28221|Deltaproteobacteria	IQ	synthase	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ketoacyl-synt
YHH3_k127_11405886_0	1278073.MYSTI_06909	1.241e-108	362.0	COG5351@1|root,COG5351@2|Bacteria,1R3ZF@1224|Proteobacteria,42XPV@68525|delta/epsilon subdivisions,2WTG6@28221|Deltaproteobacteria,2YY52@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2169)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2169,Pentapeptide
YHH3_k127_11405935_1	1210884.HG799467_gene13222	2.127e-124	413.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_11405935_0	344747.PM8797T_14594	1.388e-135	447.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_11427965_4	494419.ALPM01000004_gene1758	6.704e-06	49.0	COG2963@1|root,COG2963@2|Bacteria,2IPC7@201174|Actinobacteria,1WC82@1268|Micrococcaceae	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
YHH3_k127_11427965_3	113355.CM001775_gene3484	2.455e-07	57.0	COG2337@1|root,COG2337@2|Bacteria,1G5NV@1117|Cyanobacteria	1117|Cyanobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH3_k127_11427965_0	382464.ABSI01000010_gene3324	3.947e-74	259.0	COG1893@1|root,COG1893@2|Bacteria,46SK2@74201|Verrucomicrobia,2IU3H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
YHH3_k127_11427965_1	1353529.M899_0212	1.614e-46	173.0	COG2322@1|root,COG2322@2|Bacteria,1N3YI@1224|Proteobacteria,430G9@68525|delta/epsilon subdivisions,2WVW0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
YHH3_k127_11427965_2	583355.Caka_1247	1.448e-43	170.0	COG2372@1|root,COG2372@2|Bacteria,46XYG@74201|Verrucomicrobia,3K7DU@414999|Opitutae	414999|Opitutae	S	response to copper ion	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11440485_1	96561.Dole_0847	1.283e-60	212.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,42NYT@68525|delta/epsilon subdivisions,2WIM3@28221|Deltaproteobacteria,2MHKU@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Alpha amylase, C-terminal all-beta domain	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
YHH3_k127_11440485_0	1499967.BAYZ01000028_gene1333	7.977e-173	556.0	COG3829@1|root,COG3829@2|Bacteria,2NQNU@2323|unclassified Bacteria	2|Bacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
YHH3_k127_11466999_0	240016.ABIZ01000001_gene5466	3.925e-141	461.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_11466999_1	1134474.O59_004309	1.168e-06	61.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,1RYVX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
YHH3_k127_11468274_3	1396141.BATP01000025_gene970	2.48e-87	296.0	COG1129@1|root,COG1129@2|Bacteria,46SG6@74201|Verrucomicrobia,2IV5X@203494|Verrucomicrobiae	2|Bacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
YHH3_k127_11468274_2	1254432.SCE1572_50535	7.387e-91	309.0	COG1879@1|root,COG1879@2|Bacteria,1MU95@1224|Proteobacteria	1224|Proteobacteria	G	Periplasmic binding protein LacI transcriptional regulator	alsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
YHH3_k127_11468274_0	1434325.AZQN01000003_gene2454	7.344e-306	951.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,47KZ5@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycosyl Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
YHH3_k127_11468274_4	1434325.AZQN01000003_gene2454	3.029e-42	156.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,47KZ5@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycosyl Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
YHH3_k127_11468274_1	760011.Spico_0105	5.833e-231	729.0	COG1882@1|root,COG1882@2|Bacteria,2J6MA@203691|Spirochaetes	203691|Spirochaetes	H	formate C-acetyltransferase	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
YHH3_k127_11471562_0	1122931.AUAE01000007_gene1342	4.312e-253	815.0	COG0457@1|root,COG0457@2|Bacteria,4NKMF@976|Bacteroidetes,2FXC5@200643|Bacteroidia,231HD@171551|Porphyromonadaceae	1122931.AUAE01000007_gene1342|-	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11471562_1	583355.Caka_1040	4.856e-168	544.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	Z012_03425	-	3.1.6.14	ko:K01137,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_11471562_2	1122194.AUHU01000003_gene2272	3.216e-41	159.0	28K42@1|root,2Z9T6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
YHH3_k127_11487725_2	143224.JQMD01000002_gene3430	6.662e-102	335.0	COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,1HYCR@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
YHH3_k127_11487725_3	382464.ABSI01000005_gene1075	2.961e-97	323.0	COG0235@1|root,COG0235@2|Bacteria,46U10@74201|Verrucomicrobia,2IUBM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
YHH3_k127_11487725_1	1166948.JPZL01000001_gene3014	1.201e-106	357.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,1RNZN@1236|Gammaproteobacteria,1XJKW@135619|Oceanospirillales	135619|Oceanospirillales	G	Converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
YHH3_k127_11487725_4	583355.Caka_2414	2.772e-88	306.0	COG1459@1|root,COG1459@2|Bacteria,46UIF@74201|Verrucomicrobia,3K7U0@414999|Opitutae	414999|Opitutae	NU	secretion system	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
YHH3_k127_11487725_0	583355.Caka_2674	3.941e-200	636.0	COG2804@1|root,COG2804@2|Bacteria,46UIY@74201|Verrucomicrobia,3K7E3@414999|Opitutae	414999|Opitutae	NU	Secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
YHH3_k127_11493952_0	1121939.L861_10855	9.481e-42	171.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XH82@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
YHH3_k127_11493952_1	278957.ABEA03000017_gene2960	2.249e-12	72.0	COG2197@1|root,COG2197@2|Bacteria,46XU7@74201|Verrucomicrobia,3K85E@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_11515946_1	1265505.ATUG01000001_gene4372	4.394e-72	248.0	COG2391@1|root,COG2391@2|Bacteria,1R5DN@1224|Proteobacteria,42RX6@68525|delta/epsilon subdivisions,2WNK5@28221|Deltaproteobacteria,2MJTE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YHH3_k127_11515946_3	621372.ACIH01000208_gene2523	1.059e-47	190.0	COG3119@1|root,COG3119@2|Bacteria,1TSUU@1239|Firmicutes,4HW4X@91061|Bacilli,26YQV@186822|Paenibacillaceae	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_11515946_0	240016.ABIZ01000001_gene617	1.018e-75	274.0	2DZRA@1|root,32VGT@2|Bacteria,46TAC@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
YHH3_k127_11515946_2	1396418.BATQ01000020_gene5035	2.35e-70	245.0	COG3119@1|root,COG3119@2|Bacteria,46ZJS@74201|Verrucomicrobia,2IVBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_11519619_3	765912.Thimo_0664	1.098e-10	68.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
YHH3_k127_11519619_1	595460.RRSWK_06275	5.963e-114	395.0	COG2319@1|root,COG2319@2|Bacteria,2J51X@203682|Planctomycetes	203682|Planctomycetes	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11519619_0	234267.Acid_2265	1.082e-155	507.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH3_k127_11519619_2	234267.Acid_2264	1.973e-15	79.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
YHH3_k127_11524976_1	595460.RRSWK_03845	6.806e-209	661.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_11524976_0	1265503.KB905169_gene325	6.748e-250	795.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YHH3_k127_11524976_2	595460.RRSWK_06850	2.65e-34	132.0	COG0524@1|root,COG0524@2|Bacteria,2IWUH@203682|Planctomycetes	203682|Planctomycetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
YHH3_k127_1152813_0	583355.Caka_1944	2.31e-76	269.0	COG1195@1|root,COG1195@2|Bacteria,46UKV@74201|Verrucomicrobia,3K7K7@414999|Opitutae	414999|Opitutae	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
YHH3_k127_1152813_1	583355.Caka_1969	1.587e-69	244.0	COG0730@1|root,COG0730@2|Bacteria,46VE4@74201|Verrucomicrobia,3K7RM@414999|Opitutae	414999|Opitutae	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH3_k127_1152813_2	382464.ABSI01000009_gene3934	4.188e-47	176.0	COG0817@1|root,COG0817@2|Bacteria,46T3Y@74201|Verrucomicrobia,2IUA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
YHH3_k127_1152813_3	583355.Caka_2487	1.097e-16	85.0	COG0052@1|root,COG0052@2|Bacteria,46SNG@74201|Verrucomicrobia,3K7D6@414999|Opitutae	414999|Opitutae	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YHH3_k127_11560010_2	1499967.BAYZ01000157_gene595	5.308e-63	226.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	MFS_1
YHH3_k127_11560010_4	452637.Oter_3841	1.132e-19	96.0	COG0782@1|root,COG0782@2|Bacteria,46T65@74201|Verrucomicrobia,3K8BG@414999|Opitutae	414999|Opitutae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11560010_5	443143.GM18_2200	3.791e-07	59.0	COG3009@1|root,COG3009@2|Bacteria,1N8BW@1224|Proteobacteria,42UW2@68525|delta/epsilon subdivisions,2WQFD@28221|Deltaproteobacteria,43VBT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
YHH3_k127_11560010_3	309807.SRU_0342	7.428e-38	155.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	pqiB	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
YHH3_k127_11560010_0	335543.Sfum_2415	1.099e-91	311.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2WKHW@28221|Deltaproteobacteria,2MQ9V@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YHH3_k127_11560010_1	309807.SRU_0344	1.698e-67	236.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YHH3_k127_11592434_0	765420.OSCT_2236	1.062e-223	716.0	COG3292@1|root,COG3829@1|root,COG4585@1|root,COG3292@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,2G7P1@200795|Chloroflexi	200795|Chloroflexi	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
YHH3_k127_11615406_0	289376.THEYE_A0212	3.802e-34	138.0	COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,3J1AJ@40117|Nitrospirae	40117|Nitrospirae	NU	Bacterial type II and III secretion system protein	-	-	-	ko:K12282	-	-	-	-	ko00000,ko02044	-	-	-	Secretin
YHH3_k127_11615406_1	123214.PERMA_0973	0.0005528	49.0	292M9@1|root,2ZQ56@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11617551_1	926569.ANT_20470	1.991e-10	64.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
YHH3_k127_11630359_1	1265503.KB905169_gene247	3.041e-76	261.0	COG2755@1|root,COG2755@2|Bacteria,1RDF0@1224|Proteobacteria,1S4J6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH3_k127_11630359_2	1168065.DOK_16513	2.146e-62	222.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1J610@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Riboflavin synthase	ribE-2	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
YHH3_k127_11630359_3	502025.Hoch_3486	1.396e-16	90.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
YHH3_k127_11630359_0	382464.ABSI01000012_gene2184	3.098e-78	291.0	COG1629@1|root,COG1629@2|Bacteria,46TVI@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_11640435_0	1209072.ALBT01000007_gene2717	1.681e-122	410.0	COG2273@1|root,COG3291@1|root,COG2273@2|Bacteria,COG3291@2|Bacteria,1N5RS@1224|Proteobacteria,1RSMD@1236|Gammaproteobacteria,1FHVH@10|Cellvibrio	1236|Gammaproteobacteria	G	Glycosyl hydrolase catalytic core	lamA	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_cc,PKD
YHH3_k127_11640435_2	1449355.JQNR01000004_gene1305	4.732e-08	67.0	COG3693@1|root,COG4733@1|root,COG3693@2|Bacteria,COG4733@2|Bacteria,2GJSN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_2,CBM_3,Glyco_hydro_10,fn3
YHH3_k127_11640435_3	313598.MED152_02085	0.0009693	53.0	COG2273@1|root,COG3291@1|root,COG2273@2|Bacteria,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
YHH3_k127_11640435_1	2850.Phatr54973	4.193e-55	201.0	COG2273@1|root,2S1W9@2759|Eukaryota	2759|Eukaryota	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
YHH3_k127_11641463_1	886293.Sinac_0949	9.333e-92	319.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
YHH3_k127_11641463_0	1121859.KB890750_gene246	1.25e-191	611.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes	976|Bacteroidetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_11655203_0	485913.Krac_3483	2.554e-151	490.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
YHH3_k127_11659033_1	313628.LNTAR_12251	7.519e-47	183.0	2F8GG@1|root,340VA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11659033_3	386456.JQKN01000012_gene1081	9.445e-06	58.0	COG0577@1|root,arCOG02312@2157|Archaea	2157|Archaea	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH3_k127_11659033_0	344747.PM8797T_31643	6.813e-47	177.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003,ko:K05685,ko:K09810	ko02010,map02010	M00255,M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12,3.A.1.125	-	-	ABC_tran
YHH3_k127_11659033_2	313628.LNTAR_12216	2.203e-08	57.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH3_k127_11662606_1	1254432.SCE1572_51570	3.266e-60	213.0	COG3568@1|root,COG3568@2|Bacteria,1PPNP@1224|Proteobacteria,42QW2@68525|delta/epsilon subdivisions,2WMRN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH3_k127_11662606_0	583355.Caka_3041	3.438e-134	439.0	COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,46ZK7@74201|Verrucomicrobia,3K9BP@414999|Opitutae	414999|Opitutae	EGP	Major Facilitator Superfamily	-	-	-	ko:K08227	-	-	-	-	ko00000,ko02000	2.A.1.42	-	-	MFS_1
YHH3_k127_11677957_1	1307759.JOMJ01000003_gene194	3.509e-58	209.0	COG0135@1|root,COG0135@2|Bacteria,1RA5Q@1224|Proteobacteria,42T4S@68525|delta/epsilon subdivisions,2WP9V@28221|Deltaproteobacteria,2MBPM@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the TrpF family	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
YHH3_k127_11677957_0	765420.OSCT_0795	5.157e-66	234.0	COG1940@1|root,COG1940@2|Bacteria,2G7NH@200795|Chloroflexi,376TI@32061|Chloroflexia	32061|Chloroflexia	GK	ROK family	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH3_k127_11677957_3	517418.Ctha_0695	3.705e-35	139.0	COG0295@1|root,COG0295@2|Bacteria,1FFBW@1090|Chlorobi	1090|Chlorobi	F	AP2 domain	-	-	-	-	-	-	-	-	-	-	-	-	AP2
YHH3_k127_11677957_2	575540.Isop_0121	2.635e-55	199.0	COG2170@1|root,COG2170@2|Bacteria,2IXAU@203682|Planctomycetes	203682|Planctomycetes	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
YHH3_k127_11689543_0	382464.ABSI01000011_gene2518	2.85e-236	749.0	COG0841@1|root,COG0841@2|Bacteria,46UEW@74201|Verrucomicrobia,2IV6M@203494|Verrucomicrobiae	2|Bacteria	V	AcrB/AcrD/AcrF family	acrD	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
YHH3_k127_11689543_1	1033802.SSPSH_001914	4.927e-74	262.0	COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18990	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH3_k127_11694842_0	1123070.KB899253_gene1108	5.804e-196	621.0	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia,2IU4V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	C-terminal region of aryl-sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
YHH3_k127_11694842_1	1288963.ADIS_1944	6.047e-85	297.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,47KYK@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_11694842_2	1121904.ARBP01000032_gene2003	1.586e-52	190.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,EcsC
YHH3_k127_1171648_0	1283300.ATXB01000002_gene2888	2.848e-44	171.0	2DP87@1|root,330Z8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1171648_1	246969.TAM4_2361	1.689e-05	56.0	arCOG07088@1|root,arCOG07088@2157|Archaea,2Y2HG@28890|Euryarchaeota,243CZ@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11761633_1	794903.OPIT5_27165	1.1e-201	631.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,3K7KM@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YHH3_k127_11761633_2	583355.Caka_2097	3.56e-170	540.0	COG0468@1|root,COG0468@2|Bacteria,46SIZ@74201|Verrucomicrobia,3K737@414999|Opitutae	414999|Opitutae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
YHH3_k127_11761633_13	1156937.MFUM_220013	4.564e-19	87.0	COG0267@1|root,COG0267@2|Bacteria,46T91@74201|Verrucomicrobia,37HBR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
YHH3_k127_11761633_0	794903.OPIT5_28345	3.691e-229	726.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,3K740@414999|Opitutae	414999|Opitutae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH3_k127_11761633_6	382464.ABSI01000005_gene1243	2.246e-128	432.0	COG0358@1|root,COG0358@2|Bacteria,46S6C@74201|Verrucomicrobia,2ITUJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
YHH3_k127_11761633_14	667014.Thein_0899	5.093e-08	65.0	COG0457@1|root,COG0457@2|Bacteria,2GHED@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	ChAPs (Chs5p-Arf1p-binding proteins)	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
YHH3_k127_11761633_8	382464.ABSI01000005_gene1245	2.513e-75	266.0	2F1IQ@1|root,33UJ5@2|Bacteria,46Z53@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YHH3_k127_11761633_11	382464.ABSI01000010_gene3638	1.161e-43	162.0	COG0838@1|root,COG0838@2|Bacteria,46T33@74201|Verrucomicrobia,2IUK0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YHH3_k127_11761633_5	583355.Caka_1472	2.12e-128	419.0	COG0167@1|root,COG0167@2|Bacteria,46S5W@74201|Verrucomicrobia,3K7GG@414999|Opitutae	414999|Opitutae	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YHH3_k127_11761633_9	452637.Oter_2489	2.953e-73	255.0	2C6QH@1|root,33V43@2|Bacteria,46V9K@74201|Verrucomicrobia,3K7BV@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11761633_4	452637.Oter_2487	2.243e-137	445.0	COG0113@1|root,COG0113@2|Bacteria,46S91@74201|Verrucomicrobia,3K7HG@414999|Opitutae	414999|Opitutae	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
YHH3_k127_11761633_3	583355.Caka_1541	2.476e-160	518.0	COG0215@1|root,COG0215@2|Bacteria,46SES@74201|Verrucomicrobia,3K7N2@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
YHH3_k127_11761633_10	118168.MC7420_1737	2.202e-61	220.0	COG1073@1|root,COG1073@2|Bacteria,1G2EP@1117|Cyanobacteria,1H83Z@1150|Oscillatoriales	1117|Cyanobacteria	S	of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S9
YHH3_k127_11761633_12	55529.EKX54446	7.517e-41	157.0	COG0693@1|root,KOG2764@2759|Eukaryota	2759|Eukaryota	J	guanine deglycation, methylglyoxal removal	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
YHH3_k127_11761633_7	583355.Caka_2985	5.441e-94	322.0	COG0823@1|root,COG0823@2|Bacteria,46SSK@74201|Verrucomicrobia,3K7CU@414999|Opitutae	414999|Opitutae	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
YHH3_k127_11762338_0	382464.ABSI01000005_gene1191	5.04e-271	863.0	COG1197@1|root,COG1197@2|Bacteria,46S6Y@74201|Verrucomicrobia,2ITM9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	TRCF	-	-	-	-	-	-	-	-	-	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
YHH3_k127_11762338_2	1378168.N510_02925	5.823e-54	198.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes	1239|Firmicutes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YHH3_k127_11762338_1	382464.ABSI01000005_gene1193	9.747e-106	352.0	COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia,2IU01@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YHH3_k127_11762338_3	1397696.KK211189_gene2556	0.0002223	43.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11766166_1	1123242.JH636434_gene3814	2.316e-52	194.0	COG3119@1|root,COG3119@2|Bacteria,2IY75@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_11766166_0	344747.PM8797T_07377	1.108e-230	721.0	COG3119@1|root,COG3119@2|Bacteria,2IY75@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_11774271_3	583355.Caka_2447	2.249e-17	84.0	COG1678@1|root,COG1678@2|Bacteria,46VUF@74201|Verrucomicrobia,3K7ZM@414999|Opitutae	414999|Opitutae	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
YHH3_k127_11774271_0	583355.Caka_2446	1.441e-65	227.0	COG2131@1|root,COG2131@2|Bacteria,46WJA@74201|Verrucomicrobia,3K7XK@414999|Opitutae	414999|Opitutae	F	dCMP deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
YHH3_k127_11774271_1	1313421.JHBV01000032_gene1615	3.521e-40	156.0	COG0705@1|root,COG0705@2|Bacteria,4NQJW@976|Bacteroidetes	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH3_k127_11774271_2	314292.VAS14_11269	2.98e-32	135.0	COG0637@1|root,COG0637@2|Bacteria,1R8Z3@1224|Proteobacteria,1S4ZI@1236|Gammaproteobacteria,1XT2Y@135623|Vibrionales	135623|Vibrionales	S	phosphatase phosphohexomutase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH3_k127_11788119_1	1502851.FG93_04755	3.631e-157	504.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,3JT6J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C
YHH3_k127_11788119_3	498211.CJA_1136	1.567e-15	81.0	COG2721@1|root,COG2721@2|Bacteria,1NASV@1224|Proteobacteria,1SF6F@1236|Gammaproteobacteria,1FHIN@10|Cellvibrio	1236|Gammaproteobacteria	G	SAF	-	-	-	-	-	-	-	-	-	-	-	-	SAF
YHH3_k127_11788119_2	926556.Echvi_3778	6.795e-149	484.0	COG3119@1|root,COG3119@2|Bacteria,4NDYQ@976|Bacteroidetes	976|Bacteroidetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_11788119_0	313628.LNTAR_22429	3.133e-231	726.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_11788119_4	1434325.AZQN01000002_gene1132	1.794e-11	66.0	COG3119@1|root,COG3119@2|Bacteria,4NGJU@976|Bacteroidetes,47MMU@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_11788119_5	143224.JQMD01000002_gene1578	7.082e-10	61.0	COG3119@1|root,COG3119@2|Bacteria,4NGJU@976|Bacteroidetes,1I09W@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_11801694_1	187272.Mlg_0651	1.031e-69	255.0	COG1538@1|root,COG1538@2|Bacteria,1R705@1224|Proteobacteria,1S0X1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_11801694_0	690850.Desaf_3621	2.973e-240	776.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YHH3_k127_11801694_2	382464.ABSI01000013_gene1614	5.005e-52	203.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YHH3_k127_11801694_3	1150600.ADIARSV_0051	2.101e-08	55.0	COG2721@1|root,COG2721@2|Bacteria,4NKZW@976|Bacteroidetes,1IWKP@117747|Sphingobacteriia	976|Bacteroidetes	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	-	-	-	-	-	-	-	-	-	-	GD_AH_C
YHH3_k127_11810680_4	583355.Caka_2123	2.568e-90	307.0	COG0168@1|root,COG0168@2|Bacteria	2|Bacteria	P	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA	trkH	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662	-	ko:K03498,ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	iECDH1ME8569_1439.ECDH1ME8569_1308,iPC815.YPO3762,iSFV_1184.SFV_3651	TrkH
YHH3_k127_11810680_3	583355.Caka_2321	4.884e-103	345.0	COG1131@1|root,COG1131@2|Bacteria,46UAZ@74201|Verrucomicrobia,3K7S3@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_11810680_7	583355.Caka_2320	4.003e-60	216.0	COG1277@1|root,COG1277@2|Bacteria,46T0W@74201|Verrucomicrobia,3K7JF@414999|Opitutae	414999|Opitutae	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
YHH3_k127_11810680_2	583355.Caka_2319	1.414e-104	357.0	COG3225@1|root,COG3225@2|Bacteria,46SRK@74201|Verrucomicrobia,3K735@414999|Opitutae	414999|Opitutae	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
YHH3_k127_11810680_6	583355.Caka_2318	6.698e-63	239.0	2DN50@1|root,32VJ4@2|Bacteria,46TKZ@74201|Verrucomicrobia,3K748@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
YHH3_k127_11810680_14	278957.ABEA03000092_gene4493	8.052e-14	86.0	COG2982@1|root,COG2982@2|Bacteria,46YU9@74201|Verrucomicrobia,3K7VE@414999|Opitutae	414999|Opitutae	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
YHH3_k127_11810680_10	583355.Caka_1863	2.531e-41	157.0	COG0511@1|root,COG0511@2|Bacteria,46SXA@74201|Verrucomicrobia,3K861@414999|Opitutae	414999|Opitutae	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
YHH3_k127_11810680_0	452637.Oter_1675	1.698e-208	658.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia,3K78R@414999|Opitutae	414999|Opitutae	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YHH3_k127_11810680_13	794903.OPIT5_17045	3.243e-17	87.0	COG1302@1|root,COG1302@2|Bacteria,46WB6@74201|Verrucomicrobia,3K8GC@414999|Opitutae	414999|Opitutae	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
YHH3_k127_11810680_11	583355.Caka_0386	6.732e-37	144.0	COG0394@1|root,COG0394@2|Bacteria,46W2V@74201|Verrucomicrobia,3K7ZS@414999|Opitutae	414999|Opitutae	T	low molecular weight	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YHH3_k127_11810680_9	1235755.ANAM01000008_gene1612	3.235e-42	161.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,4HGXD@91061|Bacilli,4H19C@90964|Staphylococcaceae	91061|Bacilli	G	Ribose/Galactose Isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
YHH3_k127_11810680_1	583355.Caka_2407	1.097e-184	586.0	COG0112@1|root,COG0112@2|Bacteria,46S5I@74201|Verrucomicrobia,3K79I@414999|Opitutae	414999|Opitutae	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
YHH3_k127_11810680_8	313612.L8106_01587	1.241e-59	214.0	COG0566@1|root,COG0566@2|Bacteria,1G05W@1117|Cyanobacteria,1HAR0@1150|Oscillatoriales	1117|Cyanobacteria	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylas_C,SpoU_methylase
YHH3_k127_11810680_12	583355.Caka_2868	8.496e-35	143.0	COG4701@1|root,COG4701@2|Bacteria,46W37@74201|Verrucomicrobia,3K86W@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11810680_5	583355.Caka_2867	8.381e-81	287.0	COG1295@1|root,COG1295@2|Bacteria,46USV@74201|Verrucomicrobia,3K77Z@414999|Opitutae	414999|Opitutae	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
YHH3_k127_11824745_2	880073.Calab_0484	1.386e-05	53.0	COG1629@1|root,COG4771@2|Bacteria,2NR02@2323|unclassified Bacteria	2|Bacteria	P	TonB dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH3_k127_11824745_0	1121930.AQXG01000002_gene2002	3.77e-67	260.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1IP08@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
YHH3_k127_11824745_1	518766.Rmar_2561	2.599e-59	224.0	COG1523@1|root,COG3291@1|root,COG1523@2|Bacteria,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,1FJYC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11825260_4	382464.ABSI01000013_gene1587	3.351e-14	74.0	COG4775@1|root,COG4775@2|Bacteria,46TFS@74201|Verrucomicrobia,2IUB4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
YHH3_k127_11825260_5	452637.Oter_3490	3.839e-12	76.0	COG4775@1|root,COG4775@2|Bacteria,46TW0@74201|Verrucomicrobia,3K7BR@414999|Opitutae	414999|Opitutae	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
YHH3_k127_11825260_2	1123248.KB893316_gene4564	1.021e-45	173.0	COG0702@1|root,COG0702@2|Bacteria,4NGMR@976|Bacteroidetes,1ISJA@117747|Sphingobacteriia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YHH3_k127_11825260_1	497964.CfE428DRAFT_4513	5.651e-206	656.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	MA20_44000	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_11825260_0	497964.CfE428DRAFT_2173	8.394e-263	815.0	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
YHH3_k127_11825260_3	1219077.VAZ01S_014_00340	3.417e-15	89.0	COG0265@1|root,COG3325@1|root,COG0265@2|Bacteria,COG3325@2|Bacteria,1MWCG@1224|Proteobacteria,1RZKK@1236|Gammaproteobacteria,1XWTZ@135623|Vibrionales	135623|Vibrionales	GO	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	DUF1565
YHH3_k127_11876352_0	880070.Cycma_1215	4.198e-179	567.0	COG3119@1|root,COG3119@2|Bacteria,4NE6V@976|Bacteroidetes,47T92@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_11876352_1	595460.RRSWK_01712	9.151e-100	332.0	COG3119@1|root,COG3119@2|Bacteria,2J1WU@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_11885139_4	595460.RRSWK_00373	7.123e-145	473.0	COG3119@1|root,COG3119@2|Bacteria,2J212@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_11885139_13	1121859.KB890755_gene1257	1.029e-38	153.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,Ricin_B_lectin
YHH3_k127_11885139_0	313628.LNTAR_05714	7.845e-169	542.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_11885139_21	347834.RHE_CH01356	4.406e-06	51.0	COG5434@1|root,COG5434@2|Bacteria,1QZ8F@1224|Proteobacteria,2V22D@28211|Alphaproteobacteria,4BINQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH3_k127_11885139_5	452637.Oter_3063	4.836e-103	372.0	COG3408@1|root,COG3408@2|Bacteria,46U0C@74201|Verrucomicrobia,3K76I@414999|Opitutae	414999|Opitutae	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YHH3_k127_11885139_1	595460.RRSWK_06161	2.085e-164	531.0	COG3119@1|root,COG3507@1|root,COG3119@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43,RicinB_lectin_2,Sulfatase
YHH3_k127_11885139_11	243090.RB3497	1.534e-51	183.0	COG1172@1|root,COG1172@2|Bacteria,2IZWQ@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440,ko:K10559,ko:K10561	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	BPD_transp_2
YHH3_k127_11885139_18	1121335.Clst_1010	7.787e-17	94.0	COG5512@1|root,COG5512@2|Bacteria,1TR27@1239|Firmicutes,247Z8@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
YHH3_k127_11885139_6	525904.Tter_2778	4.26e-80	299.0	COG1409@1|root,COG3540@1|root,COG1409@2|Bacteria,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	LTD,Metallophos,Pur_ac_phosph_N
YHH3_k127_11885139_19	1112214.AHIS01000056_gene2938	6.041e-13	83.0	COG5512@1|root,COG5512@2|Bacteria,1R4BG@1224|Proteobacteria,2U415@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
YHH3_k127_11885139_3	1528106.JRJE01000008_gene1485	3.118e-149	488.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,2JR4A@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
YHH3_k127_11885139_20	1293054.HSACCH_01640	2.144e-12	75.0	2ECQ5@1|root,336MV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11885139_8	1211115.ALIQ01000198_gene465	1.933e-71	253.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VFM7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
YHH3_k127_11885139_7	382464.ABSI01000017_gene106	3.553e-78	294.0	COG1629@1|root,COG1629@2|Bacteria	382464.ABSI01000017_gene106|-	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11885139_16	748727.CLJU_c30510	1.838e-21	102.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,36IAW@31979|Clostridiaceae	186801|Clostridia	K	GntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
YHH3_k127_11885139_17	1042376.AFPK01000069_gene638	9.57e-18	98.0	COG5492@1|root,COG5492@2|Bacteria,4P01H@976|Bacteroidetes,1I7T9@117743|Flavobacteriia,406ZU@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	NQ	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
YHH3_k127_11885139_10	1385514.N782_15215	2.692e-64	231.0	COG1082@1|root,COG1082@2|Bacteria,1UITG@1239|Firmicutes,4HFIC@91061|Bacilli	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH3_k127_11885139_14	1385514.N782_15210	2.374e-35	146.0	COG1082@1|root,COG1082@2|Bacteria,1TRFN@1239|Firmicutes	1239|Firmicutes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_11885139_9	411490.ANACAC_00873	8.369e-65	228.0	COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,24FUX@186801|Clostridia	186801|Clostridia	S	Dihydroxyacetone kinase, L subunit	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
YHH3_k127_11885139_2	394503.Ccel_1639	7.976e-159	505.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,36E0T@31979|Clostridiaceae	186801|Clostridia	G	Dihydroxyacetone kinase DhaK, subunit	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
YHH3_k127_11885139_15	639030.JHVA01000001_gene3230	1.726e-34	137.0	COG0662@1|root,COG0662@2|Bacteria,3Y83R@57723|Acidobacteria	57723|Acidobacteria	G	Ectoine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YHH3_k127_11885139_12	742727.HMPREF9447_03276	4.271e-40	156.0	28IPH@1|root,2Z8PG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11925318_0	583355.Caka_0417	1.102e-157	513.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46TZV@74201|Verrucomicrobia,3K897@414999|Opitutae	414999|Opitutae	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
YHH3_k127_11925318_1	768671.ThimaDRAFT_1253	4.061e-76	263.0	28JYD@1|root,2Z9NN@2|Bacteria,1MV9T@1224|Proteobacteria,1S18H@1236|Gammaproteobacteria,1WWSD@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11925318_2	1541065.JRFE01000026_gene2155	3.422e-65	237.0	COG0116@1|root,COG0116@2|Bacteria,1G03K@1117|Cyanobacteria,3VHNJ@52604|Pleurocapsales	1117|Cyanobacteria	L	Belongs to the methyltransferase superfamily	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
YHH3_k127_11925318_3	583355.Caka_1782	1.437e-33	132.0	COG0629@1|root,COG0629@2|Bacteria,46W5D@74201|Verrucomicrobia,3K88T@414999|Opitutae	414999|Opitutae	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
YHH3_k127_11963052_3	452637.Oter_3476	2.229e-30	125.0	COG1587@1|root,COG1587@2|Bacteria	2|Bacteria	H	uroporphyrinogen-III synthase activity	hemD	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,2.5.1.61,4.2.1.75	ko:K01719,ko:K01749,ko:K13542,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084,R03165,R03194	RC00003,RC00871,RC01861,RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755,iJN678.hemD	HEM4,TP_methylase
YHH3_k127_11963052_2	583355.Caka_2959	8.088e-49	182.0	COG0135@1|root,COG0135@2|Bacteria,46VS4@74201|Verrucomicrobia,3K840@414999|Opitutae	414999|Opitutae	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
YHH3_k127_11963052_0	452637.Oter_0056	1.381e-85	293.0	COG1131@1|root,COG1131@2|Bacteria,46SWP@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_11963052_1	452637.Oter_0057	2.729e-83	293.0	COG0842@1|root,COG0842@2|Bacteria,46U3J@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH3_k127_11983288_2	1071679.BG57_23400	3.701e-12	69.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,2VHXS@28216|Betaproteobacteria,1K1AR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	type VI secretion protein	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
YHH3_k127_11983288_1	497964.CfE428DRAFT_2841	3.634e-88	302.0	COG3520@1|root,COG3520@2|Bacteria,46USB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Type VI secretion, TssG	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_TssG
YHH3_k127_11983288_0	1234364.AMSF01000056_gene1202	5.663e-151	483.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1X3FZ@135614|Xanthomonadales	135614|Xanthomonadales	O	COG0542 ATPases with chaperone activity, ATP-binding subunit	clpB1	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
YHH3_k127_12008056_0	926569.ANT_18190	5.011e-89	301.0	COG1774@1|root,COG1774@2|Bacteria,2G6AJ@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
YHH3_k127_12008056_1	357808.RoseRS_3403	6.166e-53	197.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,375NK@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YHH3_k127_12008056_2	203119.Cthe_2073	9.703e-47	172.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,3WIXP@541000|Ruminococcaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YHH3_k127_12012403_1	1123058.KB894283_gene1556	2.247e-16	91.0	COG1629@1|root,COG4771@2|Bacteria,4NFAM@976|Bacteroidetes,1HWUQ@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH3_k127_12012403_2	452637.Oter_0926	2.48e-13	75.0	COG0071@1|root,COG0071@2|Bacteria,46T3G@74201|Verrucomicrobia,3K860@414999|Opitutae	414999|Opitutae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YHH3_k127_12012403_0	523794.Lebu_1168	1.995e-30	128.0	COG0272@1|root,COG0272@2|Bacteria,3793I@32066|Fusobacteria	32066|Fusobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YHH3_k127_12022307_1	525897.Dbac_2942	1.941e-68	244.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH3_k127_12022307_2	670292.JH26_14995	1.155e-23	114.0	COG0845@1|root,COG0845@2|Bacteria,1R3R4@1224|Proteobacteria,2U45N@28211|Alphaproteobacteria,1JTQV@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K13408	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
YHH3_k127_12022307_0	710685.MycrhN_2535	4.434e-89	299.0	COG2274@1|root,COG2274@2|Bacteria,2GNB5@201174|Actinobacteria,238WK@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
YHH3_k127_12040679_2	595460.RRSWK_05456	0.0001411	45.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
YHH3_k127_12040679_1	1123070.KB899262_gene1702	1.601e-66	233.0	COG2197@1|root,COG2197@2|Bacteria,46XIF@74201|Verrucomicrobia,2IW0D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_12040679_0	497964.CfE428DRAFT_4420	1.066e-129	426.0	COG3119@1|root,COG3119@2|Bacteria,46V0M@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
YHH3_k127_12045026_1	382464.ABSI01000005_gene1144	4.359e-71	245.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia,2IU74@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_12045026_0	382464.ABSI01000005_gene1143	1.98e-147	477.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia,2IU74@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_12045026_2	756272.Plabr_1917	2.151e-11	64.0	COG3828@1|root,COG3828@2|Bacteria,2J1T0@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_1207235_2	583355.Caka_1097	1.214e-77	280.0	COG0760@1|root,COG0760@2|Bacteria,46T1I@74201|Verrucomicrobia,3K7JC@414999|Opitutae	414999|Opitutae	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
YHH3_k127_1207235_3	583355.Caka_1884	5.273e-68	241.0	COG0324@1|root,COG0324@2|Bacteria,46T1C@74201|Verrucomicrobia,3K7IR@414999|Opitutae	414999|Opitutae	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YHH3_k127_1207235_1	395495.Lcho_3607	5.579e-111	370.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,1KIZ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH3_k127_1207235_0	583355.Caka_2827	5.176e-120	392.0	COG2908@1|root,COG2908@2|Bacteria,46U19@74201|Verrucomicrobia,3K7GU@414999|Opitutae	414999|Opitutae	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH3_k127_12094107_2	583355.Caka_2371	2.126e-10	64.0	COG0545@1|root,COG0545@2|Bacteria,46VYS@74201|Verrucomicrobia,3K82D@414999|Opitutae	414999|Opitutae	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
YHH3_k127_12094107_0	794903.OPIT5_04165	1.507e-226	710.0	COG0427@1|root,COG0427@2|Bacteria,46TQC@74201|Verrucomicrobia,3K7AC@414999|Opitutae	414999|Opitutae	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
YHH3_k127_12094107_1	382464.ABSI01000007_gene4133	5.843e-122	402.0	COG5000@1|root,COG5000@2|Bacteria,46S9Q@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	ntrB	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
YHH3_k127_12094107_3	592027.CLG_B0886	1.028e-09	62.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,36DPK@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
YHH3_k127_12096721_2	583355.Caka_0619	2.579e-31	129.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,EcsC
YHH3_k127_12096721_0	1396418.BATQ01000049_gene461	1.493e-133	432.0	COG0412@1|root,COG0412@2|Bacteria,46UHK@74201|Verrucomicrobia,2ITZ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	DLH
YHH3_k127_12096721_1	1121405.dsmv_0571	4.883e-39	152.0	COG1720@1|root,COG1720@2|Bacteria,1MYVG@1224|Proteobacteria,42N6M@68525|delta/epsilon subdivisions,2WPY9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Uncharacterised protein family UPF0066	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,UPF0066
YHH3_k127_12136827_4	794903.OPIT5_28180	1.892e-18	85.0	COG0036@1|root,COG0036@2|Bacteria,46TEK@74201|Verrucomicrobia,3K7FI@414999|Opitutae	414999|Opitutae	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YHH3_k127_12136827_1	583355.Caka_1070	1.465e-89	303.0	COG1692@1|root,COG1692@2|Bacteria,46SQ2@74201|Verrucomicrobia,3K7NP@414999|Opitutae	414999|Opitutae	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
YHH3_k127_12136827_0	583355.Caka_1071	5.017e-264	825.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia,3K7KC@414999|Opitutae	414999|Opitutae	H	acetolactate synthase large subunit	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YHH3_k127_12136827_6	1123058.KB894226_gene41	9.161e-06	49.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,1HXRT@117743|Flavobacteriia	976|Bacteroidetes	P	membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
YHH3_k127_12136827_3	288000.BBta_0107	1.83e-21	97.0	COG2827@1|root,COG2827@2|Bacteria,1N04N@1224|Proteobacteria,2UCN4@28211|Alphaproteobacteria,3K0D8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
YHH3_k127_12136827_2	314230.DSM3645_29886	3.708e-74	252.0	2DBQI@1|root,2ZAEI@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
YHH3_k127_12136827_5	1173025.GEI7407_3185	1.624e-06	53.0	COG1637@1|root,COG1637@2|Bacteria,1G6DT@1117|Cyanobacteria,1HCDA@1150|Oscillatoriales	1117|Cyanobacteria	L	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
YHH3_k127_12143668_1	595460.RRSWK_01307	4.641e-223	701.0	COG3119@1|root,COG3119@2|Bacteria,2IWX1@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_12143668_0	313628.LNTAR_24526	4.119e-223	705.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	atsA_1	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_12143668_2	243090.RB13157	7.722e-186	594.0	COG3119@1|root,COG3119@2|Bacteria,2IYFP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_12143668_3	595460.RRSWK_00701	2.702e-135	447.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,FGE-sulfatase,Lactamase_B_2,PD40,Peptidase_S9
YHH3_k127_12143668_4	521674.Plim_1879	2.335e-94	331.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_12143668_6	572477.Alvin_2031	4.273e-25	109.0	2E4SV@1|root,32ZM7@2|Bacteria,1N8VN@1224|Proteobacteria,1S6AW@1236|Gammaproteobacteria,1WYH9@135613|Chromatiales	135613|Chromatiales	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
YHH3_k127_12143668_5	382464.ABSI01000017_gene32	2.025e-42	168.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_dep_Rec
YHH3_k127_12146783_2	224325.AF_0688	2.75e-54	201.0	COG1145@1|root,arCOG02189@2157|Archaea,2Y4FX@28890|Euryarchaeota	28890|Euryarchaeota	C	ferredoxin iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
YHH3_k127_12146783_3	357809.Cphy_0658	7.841e-09	66.0	COG4188@1|root,COG4188@2|Bacteria,1UJP1@1239|Firmicutes	1239|Firmicutes	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12146783_0	1280953.HOC_02883	4.724e-89	300.0	COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,2TUTU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	short-chain dehydrogenase reductase SDR	MA20_15935	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH3_k127_12146783_1	1121472.AQWN01000009_gene439	2.219e-75	259.0	COG2070@1|root,COG2070@2|Bacteria,1VTQJ@1239|Firmicutes,24ZN0@186801|Clostridia,26495@186807|Peptococcaceae	186801|Clostridia	S	FMN-dependent dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
YHH3_k127_12158164_1	583355.Caka_1667	7.969e-65	226.0	COG0100@1|root,COG0100@2|Bacteria,46STW@74201|Verrucomicrobia,3K82X@414999|Opitutae	414999|Opitutae	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YHH3_k127_12158164_2	452637.Oter_0204	1.535e-48	176.0	COG0099@1|root,COG0099@2|Bacteria,46STA@74201|Verrucomicrobia,3K83F@414999|Opitutae	414999|Opitutae	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YHH3_k127_12158164_0	583355.Caka_1669	2.341e-97	324.0	COG0024@1|root,COG0024@2|Bacteria,46SK6@74201|Verrucomicrobia,3K7C9@414999|Opitutae	414999|Opitutae	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH3_k127_12158164_3	583355.Caka_1670	6.084e-31	124.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,3K7NJ@414999|Opitutae	414999|Opitutae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YHH3_k127_12160392_3	926550.CLDAP_08980	5.788e-38	146.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
YHH3_k127_12160392_1	41431.PCC8801_4438	2.053e-116	383.0	COG0463@1|root,COG0463@2|Bacteria,1G03Y@1117|Cyanobacteria,3KHC2@43988|Cyanothece	1117|Cyanobacteria	M	PFAM glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
YHH3_k127_12160392_0	595460.RRSWK_02074	2.24e-188	601.0	COG3119@1|root,COG3119@2|Bacteria,2IX2H@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_12160392_4	382464.ABSI01000005_gene1385	2.107e-06	52.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
YHH3_k127_12195584_2	794903.OPIT5_26215	1.151e-38	147.0	COG0492@1|root,COG0492@2|Bacteria,46SC1@74201|Verrucomicrobia,3K7S7@414999|Opitutae	414999|Opitutae	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YHH3_k127_12195584_1	1121129.KB903368_gene648	2.359e-58	209.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,2FMRQ@200643|Bacteroidia,22X1I@171551|Porphyromonadaceae	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
YHH3_k127_12195584_3	583355.Caka_2059	3.34e-38	155.0	COG1426@1|root,COG1426@2|Bacteria,46VXH@74201|Verrucomicrobia,3K84R@414999|Opitutae	414999|Opitutae	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
YHH3_k127_12195584_0	583355.Caka_1816	4.642e-80	275.0	COG0084@1|root,COG0084@2|Bacteria,46U6H@74201|Verrucomicrobia,3K7YI@414999|Opitutae	414999|Opitutae	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YHH3_k127_12202396_0	583355.Caka_0248	3.772e-175	567.0	COG0659@1|root,COG0659@2|Bacteria,46THR@74201|Verrucomicrobia,3K7K8@414999|Opitutae	414999|Opitutae	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
YHH3_k127_12202396_2	1173264.KI913949_gene2585	1.509e-30	130.0	COG1738@1|root,COG1738@2|Bacteria	2|Bacteria	S	queuosine salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
YHH3_k127_12202396_3	452637.Oter_4589	1.242e-23	102.0	2E99J@1|root,333HQ@2|Bacteria,46T77@74201|Verrucomicrobia,3K8CU@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12202396_1	583355.Caka_2984	9.814e-110	363.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,46SAV@74201|Verrucomicrobia,3K75Q@414999|Opitutae	414999|Opitutae	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
YHH3_k127_12237305_4	338963.Pcar_1181	3.316e-13	71.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1PFBZ@1224|Proteobacteria,439XJ@68525|delta/epsilon subdivisions,2X1UU@28221|Deltaproteobacteria,43VBR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
YHH3_k127_12237305_1	1125863.JAFN01000001_gene3064	7.015e-51	193.0	COG0407@1|root,COG0407@2|Bacteria,1MZ5P@1224|Proteobacteria,42TMK@68525|delta/epsilon subdivisions,2WR32@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH3_k127_12237305_0	1117379.BABA_23615	2.265e-54	203.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,1ZCKH@1386|Bacillus	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YHH3_k127_12237305_2	1469245.JFBG01000013_gene1933	3.927e-24	108.0	2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria	1224|Proteobacteria	S	Selenoprotein B glycine betaine sarcosine D-proline reductase	-	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
YHH3_k127_12237305_3	909943.HIMB100_00007280	2.027e-14	77.0	2DBSD@1|root,2ZARI@2|Bacteria,1MX0F@1224|Proteobacteria,2TUNC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GRDB
YHH3_k127_12244602_5	388413.ALPR1_16179	3.519e-22	97.0	COG3119@1|root,COG3119@2|Bacteria,4NE6V@976|Bacteroidetes,47T92@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_12244602_2	595460.RRSWK_06722	1.473e-186	595.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_12244602_4	530564.Psta_4105	1.282e-25	111.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_12244602_0	313628.LNTAR_14662	3.965e-223	702.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
YHH3_k127_12244602_1	595460.RRSWK_02633	4.818e-192	629.0	COG0457@1|root,COG0457@2|Bacteria,2J18X@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12244602_3	595460.RRSWK_02632	9.261e-31	129.0	COG2304@1|root,COG2304@2|Bacteria,2IYZ1@203682|Planctomycetes	203682|Planctomycetes	A	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
YHH3_k127_12257192_3	313628.LNTAR_06859	8.126e-65	227.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL,Str_synth
YHH3_k127_12257192_4	1501230.ET33_05725	8.988e-40	160.0	COG0667@1|root,COG0667@2|Bacteria,1UHXA@1239|Firmicutes,4HDI7@91061|Bacilli,26U1C@186822|Paenibacillaceae	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_12257192_2	344747.PM8797T_16148	4.967e-83	287.0	COG1609@1|root,COG1609@2|Bacteria,2J45S@203682|Planctomycetes	203682|Planctomycetes	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
YHH3_k127_12257192_0	886293.Sinac_0920	4.9e-145	471.0	COG0673@1|root,COG0673@2|Bacteria,2IWZW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_12257192_1	497964.CfE428DRAFT_3668	1.246e-87	294.0	COG0693@1|root,COG0693@2|Bacteria,46WSV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
YHH3_k127_12257192_5	1123242.JH636435_gene1648	6.603e-36	142.0	COG1082@1|root,COG1082@2|Bacteria,2IZUP@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH3_k127_12265458_4	583355.Caka_1443	2.993e-20	91.0	COG1235@1|root,COG1235@2|Bacteria,46SRW@74201|Verrucomicrobia,3K7PE@414999|Opitutae	414999|Opitutae	S	Beta-lactamase superfamily domain	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
YHH3_k127_12265458_1	583355.Caka_0208	1.156e-144	470.0	COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia,3K7KP@414999|Opitutae	414999|Opitutae	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
YHH3_k127_12265458_0	452637.Oter_3859	2.444e-192	616.0	COG2804@1|root,COG2804@2|Bacteria,46XYI@74201|Verrucomicrobia,3K8MN@414999|Opitutae	414999|Opitutae	NU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
YHH3_k127_12265458_2	583355.Caka_0856	4.245e-32	130.0	COG2197@1|root,COG2197@2|Bacteria,46YM9@74201|Verrucomicrobia,3K9TZ@414999|Opitutae	414999|Opitutae	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
YHH3_k127_12265458_3	1137268.AZXF01000036_gene3389	4.472e-21	96.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria,4EKE7@85012|Streptosporangiales	201174|Actinobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
YHH3_k127_12265458_5	382464.ABSI01000005_gene1327	6.646e-14	73.0	2DSQH@1|root,33H1Z@2|Bacteria,46TBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12265458_6	42256.RradSPS_2424	0.0008714	46.0	COG0642@1|root,COG4251@1|root,COG5002@1|root,COG0642@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria,4CU46@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
YHH3_k127_12269025_6	1416760.AYMS01000113_gene2307	1.122e-19	93.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,1I2XU@117743|Flavobacteriia,47J2Y@76831|Myroides	976|Bacteroidetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
YHH3_k127_12269025_0	583355.Caka_1615	1.427e-195	619.0	28MGX@1|root,2ZATZ@2|Bacteria,46TJV@74201|Verrucomicrobia,3K7EP@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12269025_2	382464.ABSI01000011_gene3025	3.567e-149	480.0	COG1186@1|root,COG1186@2|Bacteria,46SAW@74201|Verrucomicrobia,2ITHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH3_k127_12269025_8	583355.Caka_2208	4.45e-06	56.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	ycgF	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822	-	ko:K06895	-	-	-	-	ko00000,ko02000	2.A.75.1	-	-	LysE
YHH3_k127_12269025_3	871968.DESME_05430	1.477e-95	323.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,264MI@186807|Peptococcaceae	186801|Clostridia	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH3_k127_12269025_4	1519464.HY22_13270	4.823e-54	201.0	COG4222@1|root,COG4222@2|Bacteria	2|Bacteria	S	Esterase-like activity of phytase	MA20_03555	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Phytase-like
YHH3_k127_12269025_7	226186.BT_4506	5.661e-08	60.0	COG0346@1|root,COG0454@1|root,COG1670@1|root,COG0346@2|Bacteria,COG0456@2|Bacteria,COG1670@2|Bacteria,4NQQA@976|Bacteroidetes,2FKZP@200643|Bacteroidia,4ANKP@815|Bacteroidaceae	976|Bacteroidetes	E	Psort location Cytoplasmic, score	gloA	-	4.4.1.5	ko:K01759,ko:K03827	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_3,Glyoxalase,Glyoxalase_4
YHH3_k127_12269025_1	382464.ABSI01000009_gene3950	4.271e-154	495.0	COG0686@1|root,COG0686@2|Bacteria,46S7U@74201|Verrucomicrobia,2ITXS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
YHH3_k127_12269025_5	1469613.JT55_04295	2.957e-23	106.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2TR5T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
YHH3_k127_12292033_2	665571.STHERM_c19270	2.408e-40	158.0	COG0705@1|root,COG0705@2|Bacteria,2J7J3@203691|Spirochaetes	203691|Spirochaetes	S	PFAM Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid
YHH3_k127_12292033_0	583355.Caka_2446	5.852e-66	228.0	COG2131@1|root,COG2131@2|Bacteria,46WJA@74201|Verrucomicrobia,3K7XK@414999|Opitutae	414999|Opitutae	F	dCMP deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
YHH3_k127_12292033_1	583355.Caka_2447	6.19e-50	183.0	COG1678@1|root,COG1678@2|Bacteria,46VUF@74201|Verrucomicrobia,3K7ZM@414999|Opitutae	414999|Opitutae	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
YHH3_k127_12304831_2	448385.sce4286	9.913e-09	61.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42QX1@68525|delta/epsilon subdivisions,2WMNH@28221|Deltaproteobacteria,2Z2XP@29|Myxococcales	28221|Deltaproteobacteria	S	Transporter associated domain	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
YHH3_k127_12304831_3	351160.RRC359	0.0001352	52.0	arCOG10895@1|root,arCOG10895@2157|Archaea	351160.RRC359|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12304831_0	1304880.JAGB01000001_gene547	1.732e-130	426.0	COG0454@1|root,COG0456@2|Bacteria,1TT30@1239|Firmicutes,24DE0@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH3_k127_12304831_1	1296416.JACB01000026_gene3930	2.541e-43	164.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NGKK@976|Bacteroidetes,1HX0I@117743|Flavobacteriia,2YKMC@290174|Aquimarina	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
YHH3_k127_12320411_0	234267.Acid_4607	8.108e-265	851.0	COG3250@1|root,COG3250@2|Bacteria,3Y47P@57723|Acidobacteria	57723|Acidobacteria	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_12320411_2	313628.LNTAR_00405	1.257e-183	584.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
YHH3_k127_12320411_3	1265503.KB905169_gene248	8.63e-182	580.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,1RMJ0@1236|Gammaproteobacteria	1224|Proteobacteria	P	choline-sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,HemolysinCabind,Sulfatase
YHH3_k127_12320411_1	313603.FB2170_03330	7.982e-221	700.0	COG3119@1|root,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,1HZGN@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_12320411_6	926559.JoomaDRAFT_1605	1.331e-91	310.0	COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes,1HXKC@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH3_k127_12320411_5	986075.CathTA2_0069	1.04e-93	324.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli	91061|Bacilli	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
YHH3_k127_12320411_4	1396418.BATQ01000185_gene2137	5.249e-130	420.0	COG0673@1|root,COG0673@2|Bacteria,46U2Q@74201|Verrucomicrobia,2IV92@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_12365432_0	382464.ABSI01000010_gene3353	1.457e-85	317.0	COG1629@1|root,COG1629@2|Bacteria	382464.ABSI01000010_gene3353|-	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12365432_1	620914.JH621264_gene1665	5.818e-78	272.0	COG5434@1|root,COG5434@2|Bacteria,4NG4T@976|Bacteroidetes,1IIH4@117743|Flavobacteriia	976|Bacteroidetes	G	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
YHH3_k127_12371835_0	382464.ABSI01000021_gene369	1.389e-166	552.0	COG1480@1|root,COG1480@2|Bacteria,46S4P@74201|Verrucomicrobia,2ITIA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,HD
YHH3_k127_12371835_2	382464.ABSI01000021_gene368	1.9e-28	120.0	COG0319@1|root,COG0319@2|Bacteria,46WBN@74201|Verrucomicrobia,2IUS4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
YHH3_k127_12371835_1	583355.Caka_1571	1.203e-55	203.0	COG2928@1|root,COG2928@2|Bacteria,46ZI5@74201|Verrucomicrobia,3K82R@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
YHH3_k127_12376265_0	588596.U9SJL4	8.372e-144	462.0	COG0155@1|root,KOG0560@2759|Eukaryota,38B7M@33154|Opisthokonta,3NV1H@4751|Fungi	4751|Fungi	P	Sulfite reductase	MET5	GO:0000096,GO:0000097,GO:0000103,GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009337,GO:0009403,GO:0009404,GO:0009987,GO:0010494,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0017144,GO:0019419,GO:0019748,GO:0019752,GO:0032991,GO:0035770,GO:0036464,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046394,GO:0050311,GO:0055114,GO:0070813,GO:0070814,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_1,NIR_SIR,NIR_SIR_ferr,POR_N
YHH3_k127_12376265_2	7209.EFO22354.2	1.093e-14	80.0	COG2105@1|root,KOG4450@2759|Eukaryota,394Q3@33154|Opisthokonta,3C9QE@33208|Metazoa,3DQV3@33213|Bilateria,40F8G@6231|Nematoda,1KX80@119089|Chromadorea	33208|Metazoa	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	ko:K19761	-	-	-	-	ko00000,ko01000	-	-	-	GGACT
YHH3_k127_12376265_1	699248.SRA_04506	3.34e-96	321.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YHH3_k127_12424667_3	768671.ThimaDRAFT_4603	1.055e-77	273.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,1RR99@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH3_k127_12424667_0	314285.KT71_11815	2.842e-97	344.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RR2N@1236|Gammaproteobacteria,1J8R6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,DUF1800
YHH3_k127_12424667_1	794903.OPIT5_21510	2.666e-84	287.0	COG0030@1|root,COG0030@2|Bacteria,46UMH@74201|Verrucomicrobia,3K7MA@414999|Opitutae	414999|Opitutae	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YHH3_k127_12424667_2	583355.Caka_1743	4.854e-79	271.0	COG0134@1|root,COG0134@2|Bacteria,46TR6@74201|Verrucomicrobia,3K7YE@414999|Opitutae	414999|Opitutae	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
YHH3_k127_12425987_1	382464.ABSI01000011_gene2542	5.281e-128	419.0	28H6T@1|root,2Z7J4@2|Bacteria,46UZY@74201|Verrucomicrobia,2IU2J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12425987_4	929562.Emtol_3236	2.095e-22	101.0	COG2197@1|root,COG2197@2|Bacteria,4NMX5@976|Bacteroidetes,47PYR@768503|Cytophagia	976|Bacteroidetes	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_12425987_3	656519.Halsa_0439	3.217e-32	143.0	COG2202@1|root,COG3437@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG3852@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,3WBCN@53433|Halanaerobiales	186801|Clostridia	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HD,HD_5,PAS,PAS_3,PAS_4,PAS_9
YHH3_k127_12425987_0	1121097.JCM15093_536	6.097e-288	915.0	COG2605@1|root,COG2605@2|Bacteria,4NHF2@976|Bacteroidetes,2FMWG@200643|Bacteroidia,4AP97@815|Bacteroidaceae	976|Bacteroidetes	S	GHMP kinase, N-terminal domain protein	fkp	-	-	-	-	-	-	-	-	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
YHH3_k127_12425987_5	502025.Hoch_2796	6.944e-09	59.0	2CJ67@1|root,32WT5@2|Bacteria,1N65Z@1224|Proteobacteria,42UI8@68525|delta/epsilon subdivisions,2WQ2B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12425987_2	525903.Taci_1503	8e-36	141.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2924,Transposase_20
YHH3_k127_12433601_0	583355.Caka_1066	1.281e-316	979.0	COG0365@1|root,COG0365@2|Bacteria,46SBX@74201|Verrucomicrobia,3K77V@414999|Opitutae	414999|Opitutae	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YHH3_k127_12433601_1	382464.ABSI01000005_gene1186	6.288e-119	392.0	COG0809@1|root,COG0809@2|Bacteria,46SDA@74201|Verrucomicrobia,2IU22@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
YHH3_k127_12433601_4	583355.Caka_1753	4.923e-51	186.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia,3K9NK@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_12433601_7	452637.Oter_0300	4.317e-06	57.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF3379
YHH3_k127_12433601_5	754476.Q7A_1538	8.595e-40	152.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,461GC@72273|Thiotrichales	72273|Thiotrichales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YHH3_k127_12433601_3	583355.Caka_3007	5.159e-52	186.0	COG0335@1|root,COG0335@2|Bacteria,46T0S@74201|Verrucomicrobia,3K87M@414999|Opitutae	414999|Opitutae	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
YHH3_k127_12433601_2	794903.OPIT5_17970	1.073e-85	288.0	COG0336@1|root,COG0336@2|Bacteria,46TWF@74201|Verrucomicrobia,3K79N@414999|Opitutae	414999|Opitutae	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
YHH3_k127_12433601_6	382464.ABSI01000002_gene4278	1.025e-23	102.0	COG0228@1|root,COG0228@2|Bacteria,46WC2@74201|Verrucomicrobia,2IUP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S16	-	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
YHH3_k127_12437464_0	1121396.KB892979_gene1669	3.492e-87	317.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,2MK30@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
YHH3_k127_1246352_0	1341181.FLJC2902T_14140	2.043e-53	194.0	COG1770@1|root,COG1770@2|Bacteria,4NF0W@976|Bacteroidetes,1HYYK@117743|Flavobacteriia,2NUPZ@237|Flavobacterium	976|Bacteroidetes	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
YHH3_k127_1246352_2	382464.ABSI01000020_gene253	3.376e-45	170.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glyco_trans_1_4,Glycos_transf_1
YHH3_k127_1246352_3	194439.CT2140	1.021e-39	152.0	COG0824@1|root,COG0824@2|Bacteria,1FF3Z@1090|Chlorobi	1090|Chlorobi	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
YHH3_k127_1246352_5	452637.Oter_1432	1.143e-26	116.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia,3K9TR@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_1246352_4	391623.TERMP_00782	1.319e-33	137.0	COG4902@1|root,arCOG03957@2157|Archaea,2Y2WW@28890|Euryarchaeota,243M5@183968|Thermococci	183968|Thermococci	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
YHH3_k127_12492516_2	543728.Vapar_3519	7.05e-36	145.0	COG0627@1|root,COG0627@2|Bacteria,1MY73@1224|Proteobacteria,2VS12@28216|Betaproteobacteria,4AF76@80864|Comamonadaceae	28216|Betaproteobacteria	S	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YHH3_k127_12492516_1	1283284.AZUK01000001_gene2136	1.338e-66	233.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,1RPAI@1236|Gammaproteobacteria,1Y6JY@135624|Aeromonadales	135624|Aeromonadales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
YHH3_k127_12492516_0	886293.Sinac_6998	2.764e-102	350.0	COG3250@1|root,COG3250@2|Bacteria,2J54D@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
YHH3_k127_12494555_1	583355.Caka_2201	6.663e-34	134.0	COG3429@1|root,COG3429@2|Bacteria,46V1R@74201|Verrucomicrobia,3K72Y@414999|Opitutae	414999|Opitutae	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
YHH3_k127_12494555_0	583355.Caka_2200	3.492e-240	752.0	COG0364@1|root,COG0364@2|Bacteria,46SHX@74201|Verrucomicrobia,3K7RF@414999|Opitutae	414999|Opitutae	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
YHH3_k127_12497909_0	349741.Amuc_0850	2.475e-140	458.0	COG2265@1|root,COG2265@2|Bacteria,46SYJ@74201|Verrucomicrobia,2ITST@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
YHH3_k127_12497909_4	452637.Oter_0851	4.796e-33	137.0	COG0095@1|root,COG0095@2|Bacteria,46VA1@74201|Verrucomicrobia,3K80G@414999|Opitutae	414999|Opitutae	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	-
YHH3_k127_12497909_1	382464.ABSI01000021_gene358	4.802e-97	329.0	COG0079@1|root,COG0079@2|Bacteria,46SFP@74201|Verrucomicrobia,2ITIN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_12497909_2	382464.ABSI01000021_gene359	6.422e-84	294.0	COG1253@1|root,COG1253@2|Bacteria,46SMD@74201|Verrucomicrobia,2IU23@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
YHH3_k127_12497909_3	794903.OPIT5_03045	3.167e-58	223.0	COG0457@1|root,COG0457@2|Bacteria,46XMJ@74201|Verrucomicrobia,3K7KN@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12497909_5	794903.OPIT5_03035	6.556e-30	133.0	COG5338@1|root,COG5338@2|Bacteria,46XUT@74201|Verrucomicrobia,3K8B8@414999|Opitutae	414999|Opitutae	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
YHH3_k127_12497909_6	395495.Lcho_2367	5.876e-05	49.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VIY9@28216|Betaproteobacteria,1KK25@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Polysaccharide biosynthesis/export protein	epsE	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YHH3_k127_12523425_0	595460.RRSWK_02631	1.022e-128	420.0	COG2304@1|root,COG2304@2|Bacteria,2IYWC@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
YHH3_k127_12523425_1	595460.RRSWK_02632	6.402e-96	326.0	COG2304@1|root,COG2304@2|Bacteria,2IYZ1@203682|Planctomycetes	203682|Planctomycetes	A	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
YHH3_k127_12534506_13	452637.Oter_0006	1.092e-87	306.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616,Exo_endo_phos
YHH3_k127_12534506_14	396588.Tgr7_2982	5.43e-86	295.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1WXE3@135613|Chromatiales	135613|Chromatiales	G	PFAM Fructosamine	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
YHH3_k127_12534506_16	1123399.AQVE01000014_gene73	8.758e-71	248.0	28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,1S23F@1236|Gammaproteobacteria,460Z8@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12534506_10	278957.ABEA03000143_gene1053	1.622e-109	366.0	COG0337@1|root,COG0337@2|Bacteria,46SRE@74201|Verrucomicrobia,3K7IX@414999|Opitutae	414999|Opitutae	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
YHH3_k127_12534506_7	583355.Caka_1577	5.146e-130	422.0	COG0552@1|root,COG0552@2|Bacteria,46SKC@74201|Verrucomicrobia,3K7EX@414999|Opitutae	414999|Opitutae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
YHH3_k127_12534506_22	583355.Caka_1576	6.803e-47	172.0	COG0781@1|root,COG0781@2|Bacteria,46VCF@74201|Verrucomicrobia,3K81J@414999|Opitutae	414999|Opitutae	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
YHH3_k127_12534506_24	794903.OPIT5_21485	1.084e-34	139.0	COG0054@1|root,COG0054@2|Bacteria,46T5S@74201|Verrucomicrobia,3K88H@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
YHH3_k127_12534506_26	1410620.SHLA_27c000560	2.838e-25	117.0	COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,2TQZR@28211|Alphaproteobacteria,4BCPR@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
YHH3_k127_12534506_18	1231190.NA8A_00645	5.63e-64	232.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,43HVW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K12369	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
YHH3_k127_12534506_6	382464.ABSI01000011_gene2739	3.133e-171	552.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	dppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YHH3_k127_12534506_4	278957.ABEA03000086_gene2487	2.34e-199	628.0	COG0205@1|root,COG0205@2|Bacteria,46SFN@74201|Verrucomicrobia,3K7HI@414999|Opitutae	414999|Opitutae	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
YHH3_k127_12534506_17	452637.Oter_0940	4.511e-65	233.0	COG2962@1|root,COG2962@2|Bacteria,46V11@74201|Verrucomicrobia,3K82S@414999|Opitutae	414999|Opitutae	S	EamA-like transporter family	-	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
YHH3_k127_12534506_23	794903.OPIT5_29795	7.284e-45	167.0	COG0251@1|root,COG0251@2|Bacteria,46VPS@74201|Verrucomicrobia,3K819@414999|Opitutae	414999|Opitutae	J	Endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
YHH3_k127_12534506_15	382464.ABSI01000006_gene940	3.147e-71	252.0	COG0385@1|root,COG0385@2|Bacteria,46V81@74201|Verrucomicrobia,2IUMP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K14347	-	-	-	-	ko00000,ko02000,ko04147	2.A.93.1	-	-	SBF_like
YHH3_k127_12534506_29	289376.THEYE_A0042	6.532e-07	61.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH3_k127_12534506_25	583355.Caka_1714	6.582e-34	141.0	COG0457@1|root,COG0457@2|Bacteria	583355.Caka_1714|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12534506_21	452637.Oter_4167	1.028e-48	177.0	COG0735@1|root,COG0735@2|Bacteria,46VUI@74201|Verrucomicrobia,3K84G@414999|Opitutae	414999|Opitutae	P	Belongs to the Fur family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH3_k127_12534506_9	583355.Caka_1213	1.346e-117	383.0	COG0396@1|root,COG0396@2|Bacteria,46SGE@74201|Verrucomicrobia,3K7KH@414999|Opitutae	414999|Opitutae	O	ABC transporter	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
YHH3_k127_12534506_2	583355.Caka_1214	6.023e-247	768.0	COG0719@1|root,COG0719@2|Bacteria,46SGN@74201|Verrucomicrobia,3K76R@414999|Opitutae	414999|Opitutae	O	assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
YHH3_k127_12534506_8	382464.ABSI01000005_gene1097	4.825e-123	410.0	COG0719@1|root,COG0719@2|Bacteria,46S8S@74201|Verrucomicrobia,2ITRN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
YHH3_k127_12534506_19	583355.Caka_1216	2.135e-60	214.0	COG2151@1|root,COG2151@2|Bacteria,46VI1@74201|Verrucomicrobia,3K7B6@414999|Opitutae	414999|Opitutae	S	FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
YHH3_k127_12534506_0	583355.Caka_2519	0.0	1319.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46TNN@74201|Verrucomicrobia,3K7A5@414999|Opitutae	414999|Opitutae	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH3_k127_12534506_20	382464.ABSI01000010_gene3409	7.714e-51	192.0	COG0805@1|root,COG0805@2|Bacteria,46T26@74201|Verrucomicrobia,2ITNJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YHH3_k127_12534506_27	94122.Shewana3_0285	6.144e-15	76.0	COG0401@1|root,COG0401@2|Bacteria,1N7K3@1224|Proteobacteria,1SGD5@1236|Gammaproteobacteria,2QCT8@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Proteolipid membrane potential modulator	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
YHH3_k127_12534506_3	583355.Caka_0861	2.346e-222	700.0	COG0143@1|root,COG0143@2|Bacteria,46SCQ@74201|Verrucomicrobia,3K783@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
YHH3_k127_12534506_5	583355.Caka_3035	4.878e-196	621.0	COG0165@1|root,COG0165@2|Bacteria,46SCX@74201|Verrucomicrobia,3KA2P@414999|Opitutae	414999|Opitutae	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
YHH3_k127_12534506_30	1304880.JAGB01000002_gene1810	1.344e-05	57.0	COG2211@1|root,COG2211@2|Bacteria,1TRCV@1239|Firmicutes,24CK5@186801|Clostridia	186801|Clostridia	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH3_k127_12534506_28	247490.KSU1_D0540	2.731e-09	64.0	2EDD9@1|root,3379K@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3568)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3568
YHH3_k127_12534506_1	87626.PTD2_14757	1.059e-300	955.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q0BY@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_12534506_11	382464.ABSI01000010_gene3221	9.241e-94	323.0	COG0845@1|root,COG0845@2|Bacteria,46VEA@74201|Verrucomicrobia,2IUBR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
YHH3_k127_12534506_12	382464.ABSI01000010_gene3224	3.07e-90	314.0	COG1538@1|root,COG1538@2|Bacteria,46YW4@74201|Verrucomicrobia,2IU6N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_12540958_0	1117647.M5M_13595	1.598e-32	137.0	COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1J5SV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH3_k127_12552549_2	1120965.AUBV01000010_gene2754	9.704e-09	69.0	COG2911@1|root,COG3210@1|root,COG5492@1|root,COG5563@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,COG5563@2|Bacteria,4NKIP@976|Bacteroidetes,47YDC@768503|Cytophagia	976|Bacteroidetes	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
YHH3_k127_12552549_1	1123058.KB894281_gene1746	9.704e-09	69.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NM0U@976|Bacteroidetes,1I0NM@117743|Flavobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Peptidase_S8,fn3
YHH3_k127_12552549_0	446470.Snas_0537	1.698e-93	336.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
YHH3_k127_12561420_1	344747.PM8797T_07377	8.969e-118	383.0	COG3119@1|root,COG3119@2|Bacteria,2IY75@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_12561420_0	595460.RRSWK_06381	0.0	1124.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
YHH3_k127_12561420_2	113355.CM001775_gene2445	3.573e-26	112.0	COG2402@1|root,COG2402@2|Bacteria,1G79E@1117|Cyanobacteria	1117|Cyanobacteria	S	SPTR PIN domain protein like protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_12573633_2	452637.Oter_3509	1.064e-77	278.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_12573633_1	452637.Oter_3509	3.36e-87	303.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_12573633_0	243090.RB8002	1.157e-175	556.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_12576930_1	1121428.DESHY_60129___1	1.938e-09	59.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
YHH3_k127_12576930_0	324602.Caur_3784	2.616e-99	338.0	COG0438@1|root,COG0438@2|Bacteria,2G7W9@200795|Chloroflexi,3772B@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
YHH3_k127_12576930_2	247490.KSU1_C1712	4.96e-09	60.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12619472_2	1125863.JAFN01000001_gene738	2.072e-26	111.0	COG0476@1|root,COG0476@2|Bacteria,1R87S@1224|Proteobacteria,42R16@68525|delta/epsilon subdivisions,2WNMW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,ThiF,ThiS-like
YHH3_k127_12619472_4	1227488.C477_19102	3.086e-05	51.0	COG1977@1|root,arCOG00536@2157|Archaea,2XYQA@28890|Euryarchaeota,23WPF@183963|Halobacteria	183963|Halobacteria	H	COG1977 Molybdopterin converting factor, small subunit	moaD2	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
YHH3_k127_12619472_0	344747.PM8797T_31618	1.661e-105	348.0	COG0476@1|root,COG0476@2|Bacteria,2IY5K@203682|Planctomycetes	203682|Planctomycetes	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
YHH3_k127_12619472_3	319225.Plut_1723	3.99e-20	96.0	COG0730@1|root,COG0730@2|Bacteria,1FE27@1090|Chlorobi	1090|Chlorobi	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH3_k127_12619472_1	1121904.ARBP01000001_gene5599	4.696e-57	222.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_12620275_5	521674.Plim_0777	5.954e-12	74.0	COG1520@1|root,COG1520@2|Bacteria,2IWVC@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH3_k127_12620275_3	1089547.KB913013_gene3240	4.405e-114	392.0	COG1073@1|root,COG1073@2|Bacteria,4NI6C@976|Bacteroidetes,47N3Z@768503|Cytophagia	976|Bacteroidetes	S	Acetyl xylan esterase	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
YHH3_k127_12620275_4	1042376.AFPK01000044_gene2583	1.819e-32	145.0	COG3317@1|root,COG3317@2|Bacteria,4NVVX@976|Bacteroidetes,1I5WA@117743|Flavobacteriia	976|Bacteroidetes	M	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
YHH3_k127_12620275_0	1122605.KB893649_gene3740	3.761e-162	524.0	COG3540@1|root,COG3540@2|Bacteria,4PIVJ@976|Bacteroidetes,1IZN8@117747|Sphingobacteriia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
YHH3_k127_12620275_2	1121859.KB890739_gene2749	9.821e-116	399.0	COG3664@1|root,COG3664@2|Bacteria,4NHQ0@976|Bacteroidetes	976|Bacteroidetes	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_39
YHH3_k127_12620275_1	452637.Oter_2196	1.726e-126	420.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_12653390_0	1235803.C825_01831	1.097e-105	363.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,2FPEC@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 2, sugar binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
YHH3_k127_12678711_0	204669.Acid345_2310	3.097e-115	393.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
YHH3_k127_12692710_0	452637.Oter_1902	4.991e-106	359.0	COG5000@1|root,COG5000@2|Bacteria,46V9C@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YHH3_k127_12692710_1	452637.Oter_1901	9.825e-106	357.0	COG0845@1|root,COG0845@2|Bacteria,46UK7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12692710_2	452637.Oter_1900	2.796e-100	331.0	COG1136@1|root,COG1136@2|Bacteria,46TVQ@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_12692710_3	215803.DB30_8370	4.722e-54	205.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_12692710_4	204669.Acid345_0289	2.157e-07	54.0	COG0577@1|root,COG0577@2|Bacteria	204669.Acid345_0289|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12698954_1	595460.RRSWK_04098	8.925e-47	171.0	COG3119@1|root,COG4946@1|root,COG3119@2|Bacteria,COG4946@2|Bacteria,2IY4Z@203682|Planctomycetes	203682|Planctomycetes	M	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12698954_0	595460.RRSWK_03377	7.991e-91	318.0	COG3669@1|root,COG3669@2|Bacteria,2J4D6@203682|Planctomycetes	203682|Planctomycetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
YHH3_k127_1271912_4	452637.Oter_3633	2.76e-32	133.0	COG0030@1|root,COG0030@2|Bacteria,46VV9@74201|Verrucomicrobia,3K8FC@414999|Opitutae	414999|Opitutae	J	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1271912_3	452637.Oter_3634	3.663e-70	250.0	COG0644@1|root,COG0644@2|Bacteria,46THB@74201|Verrucomicrobia,3K8FT@414999|Opitutae	414999|Opitutae	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1271912_1	794903.OPIT5_19120	6.779e-93	316.0	COG3424@1|root,COG3424@2|Bacteria,46U8Y@74201|Verrucomicrobia,3K7T9@414999|Opitutae	414999|Opitutae	Q	PFAM chalcone and stilbene synthase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,FAE1_CUT1_RppA
YHH3_k127_1271912_0	1415778.JQMM01000001_gene1681	6.991e-117	388.0	COG0438@1|root,COG0438@2|Bacteria,1NMB5@1224|Proteobacteria,1RRVU@1236|Gammaproteobacteria,1J58E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Sulfotransfer_3
YHH3_k127_1271912_2	382464.ABSI01000017_gene22	3.024e-73	257.0	COG0701@1|root,COG0701@2|Bacteria,46U8J@74201|Verrucomicrobia,2IWDN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
YHH3_k127_12719884_1	583355.Caka_2455	2.237e-101	335.0	COG1249@1|root,COG1249@2|Bacteria,46S7E@74201|Verrucomicrobia,3K76N@414999|Opitutae	414999|Opitutae	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH3_k127_12719884_2	452637.Oter_2711	1.181e-16	85.0	COG1950@1|root,COG1950@2|Bacteria,46W1Z@74201|Verrucomicrobia,3K8BW@414999|Opitutae	414999|Opitutae	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
YHH3_k127_12719884_0	583355.Caka_2452	1.59e-175	561.0	COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia,3K7HY@414999|Opitutae	414999|Opitutae	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C
YHH3_k127_12719884_4	452637.Oter_0467	0.0008767	48.0	COG0658@1|root,COG0658@2|Bacteria,46V8U@74201|Verrucomicrobia,3K822@414999|Opitutae	414999|Opitutae	S	PFAM ComEC Rec2-related protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
YHH3_k127_12732331_2	67281.JNZZ01000001_gene2148	4.946e-05	55.0	COG1413@1|root,COG1413@2|Bacteria,2GKP6@201174|Actinobacteria,417F7@629295|Streptomyces griseus group	201174|Actinobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
YHH3_k127_12732331_1	313628.LNTAR_10821	1.951e-100	332.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
YHH3_k127_12732331_0	575540.Isop_2477	1.247e-100	346.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_12752747_3	583355.Caka_1188	2.409e-44	175.0	COG1643@1|root,COG1643@2|Bacteria,46TFT@74201|Verrucomicrobia,3K75C@414999|Opitutae	414999|Opitutae	L	Helicase associated domain (HA2)  Add an annotation	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
YHH3_k127_12752747_4	335541.Swol_2352	2.874e-36	147.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,42JZY@68298|Syntrophomonadaceae	186801|Clostridia	H	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
YHH3_k127_12752747_2	382464.ABSI01000011_gene3005	1.072e-110	371.0	COG0150@1|root,COG0150@2|Bacteria,46SJ4@74201|Verrucomicrobia,2ITTU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	AIR synthase related protein, N-terminal domain	-	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YHH3_k127_12752747_0	583355.Caka_1296	8.213e-281	875.0	COG0034@1|root,COG0034@2|Bacteria,46UIJ@74201|Verrucomicrobia,3K7AM@414999|Opitutae	414999|Opitutae	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
YHH3_k127_12752747_1	756499.Desde_1366	1.234e-276	867.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,260FM@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
YHH3_k127_127555_2	357808.RoseRS_4512	6.654e-45	165.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
YHH3_k127_127555_3	656519.Halsa_2162	2.725e-43	168.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,3WBWM@53433|Halanaerobiales	186801|Clostridia	P	PFAM zinc iron permease	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
YHH3_k127_127555_0	357808.RoseRS_4511	4.358e-135	434.0	COG0370@1|root,COG0370@2|Bacteria,2GAJB@200795|Chloroflexi,376HM@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	FeoB_N
YHH3_k127_127555_1	357808.RoseRS_4510	2.781e-130	419.0	COG0370@1|root,COG0370@2|Bacteria,2GBTA@200795|Chloroflexi,37667@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,Gate
YHH3_k127_12792236_0	926562.Oweho_2795	7.331e-61	237.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,CARDB,Calx-beta,Cleaved_Adhesin,DUF4465,Glyco_tran_WbsX,fn3
YHH3_k127_12802410_0	743722.Sph21_5173	4.384e-127	422.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,1IQA2@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_12802410_1	240016.ABIZ01000001_gene2571	9.675e-27	115.0	COG0492@1|root,COG1053@1|root,COG2755@1|root,COG4409@1|root,COG0492@2|Bacteria,COG1053@2|Bacteria,COG2755@2|Bacteria,COG4409@2|Bacteria,46TCP@74201|Verrucomicrobia,2IWKC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
YHH3_k127_12816920_2	247634.GPB2148_1774	3.619e-47	173.0	COG1028@1|root,COG1028@2|Bacteria,1R6NY@1224|Proteobacteria,1S0VU@1236|Gammaproteobacteria,1JAJQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	IQR COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH3_k127_12816920_0	1341646.CBMO010000080_gene321	5.083e-107	358.0	COG3804@1|root,COG3804@2|Bacteria,2IBKQ@201174|Actinobacteria,2375W@1762|Mycobacteriaceae	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
YHH3_k127_12816920_1	589924.Ferp_1233	2.838e-59	214.0	COG1028@1|root,arCOG01259@2157|Archaea,2XSWX@28890|Euryarchaeota,2469N@183980|Archaeoglobi	183980|Archaeoglobi	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH3_k127_12868844_1	452637.Oter_3766	5.306e-42	167.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_12868844_0	382464.ABSI01000010_gene3353	4.269e-57	208.0	COG1629@1|root,COG1629@2|Bacteria	382464.ABSI01000010_gene3353|-	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12882121_0	643648.Slip_0720	2.485e-44	167.0	COG0194@1|root,COG0194@2|Bacteria	2|Bacteria	F	guanylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_kin
YHH3_k127_12882121_2	1415778.JQMM01000001_gene1519	1.033e-07	63.0	COG5607@1|root,COG5607@2|Bacteria,1Q6AS@1224|Proteobacteria,1T8T5@1236|Gammaproteobacteria,1JBGZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
YHH3_k127_12882121_1	382464.ABSI01000014_gene1462	4.355e-30	124.0	COG3934@1|root,COG3934@2|Bacteria,46Z5X@74201|Verrucomicrobia,2IWQJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12885_2	1168034.FH5T_15275	4.053e-156	500.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,2FMMW@200643|Bacteroidia	976|Bacteroidetes	G	glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
YHH3_k127_12885_3	1408473.JHXO01000011_gene3177	7.418e-146	474.0	COG3875@1|root,COG3875@2|Bacteria,4NI4Z@976|Bacteroidetes,2FQM8@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
YHH3_k127_12885_0	1168034.FH5T_18270	1.446e-258	802.0	COG0362@1|root,COG0362@2|Bacteria,4NG05@976|Bacteroidetes,2FMFW@200643|Bacteroidia	976|Bacteroidetes	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
YHH3_k127_12885_1	234267.Acid_7084	6.229e-188	591.0	COG0524@1|root,COG0524@2|Bacteria,3Y3DE@57723|Acidobacteria	57723|Acidobacteria	G	PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
YHH3_k127_12885_4	927658.AJUM01000022_gene1030	8.803e-77	262.0	COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,2FMB9@200643|Bacteroidia,3XJY3@558415|Marinilabiliaceae	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
YHH3_k127_1290176_0	1122201.AUAZ01000009_gene2847	4.2e-34	135.0	COG3584@1|root,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria,1SBH0@1236|Gammaproteobacteria,46BSK@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	3D domain protein	DR0488	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1332713_3	583355.Caka_1733	1.26e-38	153.0	COG1929@1|root,COG1929@2|Bacteria,46TGW@74201|Verrucomicrobia,3K730@414999|Opitutae	414999|Opitutae	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
YHH3_k127_1332713_2	583355.Caka_1734	6.493e-56	202.0	COG3216@1|root,COG3216@2|Bacteria,46WES@74201|Verrucomicrobia,3K9VH@414999|Opitutae	414999|Opitutae	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
YHH3_k127_1332713_0	382464.ABSI01000013_gene1816	1.948e-141	461.0	COG3876@1|root,COG3876@2|Bacteria,46UR1@74201|Verrucomicrobia,2IV8D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
YHH3_k127_1332713_1	373903.Hore_02670	4.816e-113	379.0	COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes	1239|Firmicutes	G	PFAM glycoside hydrolase, family 16	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_16
YHH3_k127_1384373_0	1255043.TVNIR_3312	2.023e-85	287.0	COG4974@1|root,COG4974@2|Bacteria,1MZES@1224|Proteobacteria,1S9MN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
YHH3_k127_1384373_2	365046.Rta_27440	2.216e-49	179.0	2AXM7@1|root,31PMG@2|Bacteria,1RIYV@1224|Proteobacteria,2VUMG@28216|Betaproteobacteria,4AFSP@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1384373_1	420662.Mpe_A3611	2.215e-69	242.0	COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,2WAA3@28216|Betaproteobacteria,1KNX1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1386427_2	382464.ABSI01000010_gene3784	2.182e-45	173.0	COG1629@1|root,COG1629@2|Bacteria,46UTS@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_1386427_0	1121859.KB890750_gene265	5.288e-136	442.0	COG3291@1|root,COG3291@2|Bacteria,4NJ1K@976|Bacteroidetes	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
YHH3_k127_1386427_1	1403819.BATR01000133_gene4740	2.32e-70	252.0	COG3540@1|root,COG3540@2|Bacteria,46XER@74201|Verrucomicrobia,2IVPT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1391513_2	118005.AWNK01000004_gene1113	9.214e-18	92.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH3_k127_1391513_0	340177.Cag_1408	6.021e-120	408.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02004,ko:K07798	ko02020,map02020	M00258	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.1.4,3.A.1,8.A.1	-	-	FtsX,HlyD_3,HlyD_D23,MacB_PCD
YHH3_k127_1391513_1	340177.Cag_1407	6.039e-80	273.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH3_k127_139561_2	1232410.KI421428_gene1190	6.641e-64	222.0	COG0476@1|root,COG0476@2|Bacteria,1R87S@1224|Proteobacteria,42R16@68525|delta/epsilon subdivisions,2WNMW@28221|Deltaproteobacteria,43RZK@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	ThiS-like ubiquitin	-	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,ThiF,ThiS-like
YHH3_k127_139561_1	344747.PM8797T_31628	1.635e-72	252.0	COG3842@1|root,COG3842@2|Bacteria,2IZ85@203682|Planctomycetes	203682|Planctomycetes	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH3_k127_139561_0	595460.RRSWK_03581	1.256e-80	277.0	COG0555@1|root,COG0555@2|Bacteria,2IYJ3@203682|Planctomycetes	203682|Planctomycetes	O	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
YHH3_k127_139561_3	313628.LNTAR_12236	1.198e-54	201.0	COG0725@1|root,COG0725@2|Bacteria	2|Bacteria	P	tungstate binding	modA1	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044464	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
YHH3_k127_1410661_2	1189612.A33Q_1654	9.749e-14	74.0	28J1N@1|root,2Z8YI@2|Bacteria,4NH1X@976|Bacteroidetes,47Q2H@768503|Cytophagia	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH3_k127_1410661_3	207559.Dde_2500	1.554e-06	55.0	COG1813@1|root,COG1813@2|Bacteria,1N9TB@1224|Proteobacteria,42WF0@68525|delta/epsilon subdivisions,2WRSW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH3_k127_1410661_0	502025.Hoch_0991	1.143e-91	313.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH3_k127_1413056_0	382464.ABSI01000011_gene3052	2.306e-208	663.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia,2IU3F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	GcpE protein	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
YHH3_k127_1413056_1	323098.Nwi_0332	9.243e-24	104.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,3JQMP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
YHH3_k127_1423082_0	1449065.JMLL01000010_gene714	9.03e-56	219.0	COG5434@1|root,COG5434@2|Bacteria,1MYC2@1224|Proteobacteria,2U0PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
YHH3_k127_1435956_1	1185876.BN8_00689	1.039e-108	359.0	COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,47J96@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
YHH3_k127_1435956_0	452637.Oter_1383	1.203e-268	836.0	COG1069@1|root,COG1069@2|Bacteria,46UI3@74201|Verrucomicrobia,3K769@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
YHH3_k127_1437675_2	1142394.PSMK_14870	2.37e-24	108.0	COG1453@1|root,COG1453@2|Bacteria,2IZF3@203682|Planctomycetes	203682|Planctomycetes	S	aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_1437675_0	1121904.ARBP01000009_gene4249	1.118e-166	535.0	COG4948@1|root,COG4948@2|Bacteria,4NI24@976|Bacteroidetes,47N24@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YHH3_k127_1437675_1	1122925.KB895380_gene4092	2.87e-40	157.0	2CAEK@1|root,2ZCPG@2|Bacteria,1U07Z@1239|Firmicutes,4I9IQ@91061|Bacilli,271MJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1465118_2	452637.Oter_2690	8.237e-74	258.0	COG1561@1|root,COG1561@2|Bacteria,46V58@74201|Verrucomicrobia,3K7K3@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
YHH3_k127_1465118_0	382464.ABSI01000021_gene413	1.946e-198	624.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH3_k127_1465118_1	452637.Oter_2687	1.139e-98	331.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,46SWK@74201|Verrucomicrobia,3K87J@414999|Opitutae	414999|Opitutae	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,PAS_3,SpoIIE
YHH3_k127_149025_1	316274.Haur_3450	5.988e-13	76.0	COG0404@1|root,COG0404@2|Bacteria,2GBIM@200795|Chloroflexi,3780N@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycine cleavage T protein (aminomethyl transferase)	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YHH3_k127_149025_0	583355.Caka_2809	2.449e-35	137.0	COG0776@1|root,COG0776@2|Bacteria,46ZE7@74201|Verrucomicrobia,3K9SJ@414999|Opitutae	414999|Opitutae	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH3_k127_149025_2	319225.Plut_0648	5.135e-05	49.0	COG4679@1|root,COG4679@2|Bacteria	2|Bacteria	K	PFAM Phage derived protein Gp49-like (DUF891)	-	GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	Gp49
YHH3_k127_149025_3	1173028.ANKO01000146_gene1457	0.0002532	48.0	COG1487@1|root,COG1487@2|Bacteria,1G8EC@1117|Cyanobacteria,1HGB1@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH3_k127_1492235_0	1121875.KB907551_gene970	2.381e-165	526.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,Polysacc_deac_1
YHH3_k127_1492235_1	1150600.ADIARSV_4039	5.948e-96	339.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1IS5G@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_149848_1	382464.ABSI01000017_gene42	5.483e-35	145.0	COG3712@1|root,COG3712@2|Bacteria,46XRJ@74201|Verrucomicrobia,2IWFB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
YHH3_k127_149848_0	452637.Oter_2048	6.38e-78	293.0	COG4774@1|root,COG4774@2|Bacteria	452637.Oter_2048|-	P	siderophore transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1502344_4	1077285.AGDG01000023_gene1026	3.088e-08	60.0	COG0729@1|root,COG0729@2|Bacteria,4NVBC@976|Bacteroidetes,2FTDT@200643|Bacteroidia	976|Bacteroidetes	M	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
YHH3_k127_1502344_3	296587.XP_002504385.1	4.435e-09	63.0	2E3BA@1|root,2SAF2@2759|Eukaryota,3822D@33090|Viridiplantae,34NGR@3041|Chlorophyta	2759|Eukaryota	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
YHH3_k127_1502344_2	316274.Haur_0259	4.748e-12	73.0	COG1613@1|root,COG1613@2|Bacteria	2|Bacteria	P	Sulfate ABC transporter periplasmic sulfate-binding protein	subI	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iJN678.sbpA	SBP_bac_11
YHH3_k127_1502344_1	1396141.BATP01000007_gene5718	2.138e-24	113.0	COG1470@1|root,COG1470@2|Bacteria,46W2S@74201|Verrucomicrobia,2IW22@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1502344_0	382464.ABSI01000011_gene2386	4.043e-81	279.0	COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia,2IUZU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
YHH3_k127_1511814_2	452637.Oter_4517	4.018e-41	160.0	COG0673@1|root,COG0673@2|Bacteria,46UJR@74201|Verrucomicrobia,3K94Y@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_1511814_0	573413.Spirs_3064	2.556e-74	261.0	COG1940@1|root,COG1940@2|Bacteria,2J5SF@203691|Spirochaetes	203691|Spirochaetes	GK	Transcriptional regulator sugar kinase	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH3_k127_1511814_1	886293.Sinac_0540	2.713e-68	237.0	COG0279@1|root,COG0279@2|Bacteria,2IZQU@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
YHH3_k127_1520447_0	926561.KB900617_gene2044	1.731e-150	493.0	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,3WAGU@53433|Halanaerobiales	186801|Clostridia	P	pyridine nucleotide-disulphide oxidoreductase dimerisation	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
YHH3_k127_1520447_1	382464.ABSI01000020_gene319	6.829e-20	94.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Nitro_FeMo-Co
YHH3_k127_1528896_3	309803.CTN_0623	3.782e-28	126.0	COG3693@1|root,COG3693@2|Bacteria	2|Bacteria	G	endo-1,4-beta-xylanase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM9_1,Glyco_hydro_10
YHH3_k127_1528896_0	595460.RRSWK_04205	4.703e-195	620.0	COG3119@1|root,COG3119@2|Bacteria,2J24M@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_1528896_2	1122605.KB893637_gene3266	9.048e-74	268.0	COG3119@1|root,COG3119@2|Bacteria,4P1UT@976|Bacteroidetes	976|Bacteroidetes	P	Sulfatase	-	-	3.10.1.1	ko:K01565	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07814	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_1528896_1	344747.PM8797T_15788	6.128e-84	296.0	COG3119@1|root,COG3119@2|Bacteria,2J24M@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_1528896_4	1123311.KB904449_gene274	1.364e-09	62.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,4HBYA@91061|Bacilli	91061|Bacilli	G	arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	F5_F8_type_C,Glyco_hydro_53
YHH3_k127_1529739_0	595460.RRSWK_03605	1.106e-92	313.0	COG3828@1|root,COG3828@2|Bacteria,2J29P@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
YHH3_k127_1534226_0	439235.Dalk_1475	2.705e-113	391.0	COG1470@1|root,COG4733@1|root,COG1470@2|Bacteria,COG4733@2|Bacteria,1QW0V@1224|Proteobacteria,42U6C@68525|delta/epsilon subdivisions,2WQX8@28221|Deltaproteobacteria,2MN90@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_2,DUF4215
YHH3_k127_1548908_8	1224746.B932_1928	1.634e-45	172.0	COG0746@1|root,COG1977@1|root,COG0746@2|Bacteria,COG1977@2|Bacteria,1RKCH@1224|Proteobacteria,2VFYJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,ThiS
YHH3_k127_1548908_7	360094.PXO_02447	5.692e-46	171.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1X6FA@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
YHH3_k127_1548908_3	1234364.AMSF01000015_gene3114	1.685e-71	256.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1X5HG@135614|Xanthomonadales	135614|Xanthomonadales	H	molybdopterin biosynthesis	moeA1	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
YHH3_k127_1548908_11	497964.CfE428DRAFT_0298	1.658e-36	143.0	COG2258@1|root,COG2258@2|Bacteria,46VBP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1548908_14	313598.MED152_13174	0.0001461	47.0	COG0730@1|root,COG0730@2|Bacteria,4NIJ9@976|Bacteroidetes,1I0SR@117743|Flavobacteriia,3VW6U@52959|Polaribacter	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH3_k127_1548908_6	1485545.JQLW01000005_gene896	1.437e-51	195.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
YHH3_k127_1548908_2	1123057.P872_13075	2.273e-78	267.0	COG4122@1|root,COG4122@2|Bacteria,4PBU1@976|Bacteroidetes,47WBZ@768503|Cytophagia	976|Bacteroidetes	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
YHH3_k127_1548908_0	1047013.AQSP01000105_gene1439	3.04e-165	530.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	MA20_31530	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
YHH3_k127_1548908_5	1380600.AUYN01000006_gene752	1.122e-59	233.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,F5_F8_type_C,Pectate_lyase_3
YHH3_k127_1548908_12	1122931.AUAE01000010_gene4464	1.21e-24	117.0	COG1453@1|root,COG1453@2|Bacteria,4NJU2@976|Bacteroidetes,2G2UD@200643|Bacteroidia,231JU@171551|Porphyromonadaceae	976|Bacteroidetes	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
YHH3_k127_1548908_10	767817.Desgi_0880	8.003e-37	142.0	COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,24JTU@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YHH3_k127_1548908_1	1121456.ATVA01000012_gene2806	2.486e-118	411.0	COG3386@1|root,COG3386@2|Bacteria,1R5SU@1224|Proteobacteria	1224|Proteobacteria	G	gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3,SGL
YHH3_k127_1548908_4	583355.Caka_1277	4.217e-60	220.0	295V5@1|root,2ZT65@2|Bacteria,46WNU@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1548908_9	335543.Sfum_1659	2.489e-41	165.0	2C5Z1@1|root,33ZHM@2|Bacteria,1NXTS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1578072_8	583355.Caka_0779	1.575e-78	274.0	COG2304@1|root,COG2304@2|Bacteria,46SKE@74201|Verrucomicrobia,3K7H6@414999|Opitutae	414999|Opitutae	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
YHH3_k127_1578072_4	1167006.UWK_00742	6.987e-98	353.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
YHH3_k127_1578072_13	583355.Caka_0781	1.714e-34	151.0	COG0457@1|root,COG0457@2|Bacteria,46SMI@74201|Verrucomicrobia,3K8JA@414999|Opitutae	414999|Opitutae	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
YHH3_k127_1578072_18	1107311.Q767_08245	5.952e-09	66.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia,2NU4E@237|Flavobacterium	976|Bacteroidetes	T	BatE protein	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
YHH3_k127_1578072_17	382464.ABSI01000011_gene2987	6.82e-18	87.0	COG3937@1|root,COG3937@2|Bacteria,46WXZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1578072_0	583355.Caka_1934	8.008e-147	483.0	COG0661@1|root,COG0661@2|Bacteria,46UJV@74201|Verrucomicrobia,3K7NS@414999|Opitutae	414999|Opitutae	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
YHH3_k127_1578072_5	382464.ABSI01000005_gene1359	5.368e-87	304.0	COG0811@1|root,COG0811@2|Bacteria,46UAW@74201|Verrucomicrobia,2IVTF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
YHH3_k127_1578072_14	583355.Caka_2269	2.597e-34	140.0	COG0811@1|root,COG0811@2|Bacteria,46VPT@74201|Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH3_k127_1578072_12	382464.ABSI01000007_gene4061	1.654e-34	137.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH3_k127_1578072_16	583355.Caka_2267	9.748e-24	109.0	COG0810@1|root,COG0810@2|Bacteria,46WRI@74201|Verrucomicrobia,3K8HB@414999|Opitutae	414999|Opitutae	M	Biopolymer transporter TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH3_k127_1578072_11	583355.Caka_2266	8.232e-45	181.0	COG0457@1|root,COG0457@2|Bacteria	583355.Caka_2266|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1578072_6	794903.OPIT5_10930	9.2e-84	290.0	COG0715@1|root,COG0715@2|Bacteria,46X2C@74201|Verrucomicrobia,3K9J8@414999|Opitutae	414999|Opitutae	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
YHH3_k127_1578072_7	583355.Caka_2655	2.61e-81	282.0	COG4974@1|root,COG4974@2|Bacteria,46U04@74201|Verrucomicrobia,3K7J0@414999|Opitutae	414999|Opitutae	D	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH3_k127_1578072_10	583355.Caka_0669	3.246e-53	194.0	COG2151@1|root,COG2151@2|Bacteria,46VFI@74201|Verrucomicrobia,3K7XT@414999|Opitutae	414999|Opitutae	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
YHH3_k127_1578072_3	378806.STAUR_3802	1.791e-113	389.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42R62@68525|delta/epsilon subdivisions,2WN5J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
YHH3_k127_1578072_9	1242864.D187_010288	2.929e-68	242.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
YHH3_k127_1578072_2	1444712.BN1013_01556	1.32e-131	435.0	COG0415@1|root,COG0415@2|Bacteria,2JFX9@204428|Chlamydiae	204428|Chlamydiae	L	DNA photolyase	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
YHH3_k127_1578072_1	583355.Caka_1891	5.808e-134	434.0	COG0031@1|root,COG0031@2|Bacteria,46UMC@74201|Verrucomicrobia,3K7T4@414999|Opitutae	414999|Opitutae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH3_k127_1578727_0	1408473.JHXO01000004_gene181	4.222e-50	183.0	COG4299@1|root,COG4299@2|Bacteria,4NH8T@976|Bacteroidetes	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
YHH3_k127_1578727_1	391616.OA238_c47560	8.816e-50	191.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
YHH3_k127_1592181_0	583355.Caka_0932	0.0	1041.0	COG0296@1|root,COG0296@2|Bacteria,46SH5@74201|Verrucomicrobia,3K74A@414999|Opitutae	414999|Opitutae	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
YHH3_k127_1592181_2	794903.OPIT5_16475	9.859e-76	280.0	COG1452@1|root,COG1452@2|Bacteria,46SJX@74201|Verrucomicrobia,3K7FX@414999|Opitutae	414999|Opitutae	M	Organic solvent tolerance protein	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
YHH3_k127_1592181_1	583355.Caka_0934	2.163e-79	274.0	COG1354@1|root,COG1354@2|Bacteria,46UZS@74201|Verrucomicrobia,3K76V@414999|Opitutae	414999|Opitutae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
YHH3_k127_1599942_3	382464.ABSI01000011_gene2586	3.786e-44	166.0	COG1609@1|root,COG1609@2|Bacteria,46XF0@74201|Verrucomicrobia,2IVQK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3
YHH3_k127_1599942_0	1121930.AQXG01000003_gene2767	1.04e-318	1011.0	COG3459@1|root,COG3459@2|Bacteria,4PM7T@976|Bacteroidetes,1IVNA@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1599942_2	382464.ABSI01000023_gene586	2.814e-55	196.0	COG0346@1|root,COG0346@2|Bacteria,46SUF@74201|Verrucomicrobia,2IUKG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YHH3_k127_1599942_4	382464.ABSI01000010_gene3771	2.327e-31	128.0	2FBS3@1|root,343WW@2|Bacteria,46X6J@74201|Verrucomicrobia,2IUQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1599942_1	583355.Caka_0001	3.747e-148	482.0	COG0593@1|root,COG0593@2|Bacteria,46S6H@74201|Verrucomicrobia,3K7HJ@414999|Opitutae	414999|Opitutae	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
YHH3_k127_1623148_1	357808.RoseRS_0093	1.949e-22	114.0	COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi,37581@32061|Chloroflexia	32061|Chloroflexia	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YHH3_k127_1623148_0	1306406.ASHX01000001_gene4469	1.19e-68	263.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF11,PKD,PPC
YHH3_k127_1643401_2	1211813.CAPH01000006_gene1440	3.738e-40	157.0	COG1413@1|root,COG1413@2|Bacteria,4PMMF@976|Bacteroidetes,2G0K3@200643|Bacteroidia	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_1643401_3	1121904.ARBP01000001_gene5437	6.604e-30	121.0	COG0657@1|root,COG0657@2|Bacteria,4NJ8D@976|Bacteroidetes,47TQ4@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DLH,Lipase_GDSL_2,Peptidase_S9
YHH3_k127_1643401_0	756272.Plabr_4157	3.918e-209	667.0	COG3119@1|root,COG3119@2|Bacteria,2IXWN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_1643401_1	869213.JCM21142_93371	7.711e-177	569.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
YHH3_k127_1645745_0	903818.KI912268_gene1657	2.483e-92	313.0	COG2069@1|root,COG2069@2|Bacteria	2|Bacteria	C	one-carbon metabolic process	acsD	-	1.2.7.4,2.1.1.245	ko:K00194,ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R07157,R08034,R09096,R10219,R10243	RC00004,RC00113,RC00250,RC02800,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
YHH3_k127_1645745_1	1009370.ALO_06368	6.264e-35	139.0	COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,4H6FM@909932|Negativicutes	909932|Negativicutes	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhD,FeS
YHH3_k127_1654706_0	768706.Desor_1391	5.69e-06	61.0	COG2247@1|root,COG3386@1|root,COG2247@2|Bacteria,COG3386@2|Bacteria,1VMQN@1239|Firmicutes	1239|Firmicutes	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
YHH3_k127_166527_0	313628.LNTAR_22404	9.328e-173	552.0	COG3119@1|root,COG3119@2|Bacteria	313628.LNTAR_22404|-	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_166527_1	313603.FB2170_09456	7.161e-156	505.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1IG68@117743|Flavobacteriia,2PIQN@252356|Maribacter	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,DUF4976,Sulfatase
YHH3_k127_166527_2	455436.DS989811_gene1745	9.622e-07	53.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
YHH3_k127_1676490_2	452637.Oter_4612	3.25e-13	84.0	COG5549@1|root,COG5549@2|Bacteria,46UKP@74201|Verrucomicrobia,3KA3E@414999|Opitutae	2|Bacteria	O	Immunoglobulin I-set domain protein	-	-	3.2.1.4,3.4.24.40	ko:K01179,ko:K01406	ko00500,ko01100,ko01503,map00500,map01100,map01503	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002	-	GH5,GH9	-	CBM60,DUF4214,Glyco_hydro_16,HemolysinCabind,Peptidase_M10,Peptidase_M10_C,Reprolysin_4,W_rich_C
YHH3_k127_1676490_0	382464.ABSI01000013_gene1839	1.391e-93	340.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8
YHH3_k127_1676490_1	1123242.JH636434_gene5367	7.979e-75	263.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_168945_0	313628.LNTAR_11406	2.766e-237	746.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Glyco_hydro_31
YHH3_k127_168945_1	243090.RB1828	3.917e-85	284.0	COG3540@1|root,COG3540@2|Bacteria,2J1R1@203682|Planctomycetes	203682|Planctomycetes	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1696555_3	32057.KB217478_gene700	5.944e-23	99.0	COG5549@1|root,COG5549@2|Bacteria,1G2AK@1117|Cyanobacteria,1HKEV@1161|Nostocales	1117|Cyanobacteria	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
YHH3_k127_1696555_0	1128421.JAGA01000003_gene3009	1.296e-98	331.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,SGL,VCBS
YHH3_k127_1696555_1	926569.ANT_05870	1.202e-59	213.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	pilL	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K02487,ko:K03407,ko:K03413,ko:K06596,ko:K11526,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507,M00508,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
YHH3_k127_1696555_2	377629.TERTU_1021	2.042e-25	110.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,2PNUS@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Translation initiation factor SUI1	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
YHH3_k127_1697461_9	452637.Oter_1395	1.92e-48	181.0	COG1556@1|root,COG1556@2|Bacteria,46TAQ@74201|Verrucomicrobia,3K821@414999|Opitutae	414999|Opitutae	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
YHH3_k127_1697461_0	452637.Oter_1396	1.254e-202	642.0	COG1139@1|root,COG1139@2|Bacteria,46SBN@74201|Verrucomicrobia,3K7N0@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
YHH3_k127_1697461_5	278957.ABEA03000106_gene1827	1.301e-107	354.0	COG0247@1|root,COG0247@2|Bacteria,46UD9@74201|Verrucomicrobia,3K7SD@414999|Opitutae	414999|Opitutae	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
YHH3_k127_1697461_6	382464.ABSI01000020_gene264	2.679e-95	319.0	COG1349@1|root,COG1349@2|Bacteria,46T4S@74201|Verrucomicrobia,2IUQ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DeoR C terminal sensor domain	-	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
YHH3_k127_1697461_7	278957.ABEA03000087_gene601	2.695e-95	321.0	COG4869@1|root,COG4869@2|Bacteria,46UMP@74201|Verrucomicrobia,3K7FS@414999|Opitutae	414999|Opitutae	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
YHH3_k127_1697461_12	382464.ABSI01000020_gene266	2.578e-37	141.0	COG4577@1|root,COG4577@2|Bacteria,46W7U@74201|Verrucomicrobia	74201|Verrucomicrobia	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
YHH3_k127_1697461_10	382464.ABSI01000020_gene267	7.741e-41	152.0	COG4577@1|root,COG4577@2|Bacteria,46WBA@74201|Verrucomicrobia	74201|Verrucomicrobia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
YHH3_k127_1697461_1	382464.ABSI01000020_gene268	2.413e-192	606.0	COG0282@1|root,COG0282@2|Bacteria,46SKB@74201|Verrucomicrobia,2ITSN@203494|Verrucomicrobiae	2|Bacteria	C	Acetokinase family	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1,2.7.2.15	ko:K00925,ko:K19697	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
YHH3_k127_1697461_14	382464.ABSI01000020_gene269	3.845e-32	127.0	COG4577@1|root,COG4577@2|Bacteria,46W1J@74201|Verrucomicrobia	74201|Verrucomicrobia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
YHH3_k127_1697461_8	382464.ABSI01000020_gene270	7.711e-50	178.0	COG4576@1|root,COG4576@2|Bacteria,46VMK@74201|Verrucomicrobia	74201|Verrucomicrobia	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
YHH3_k127_1697461_16	886293.Sinac_1769	5.771e-13	73.0	COG1012@1|root,COG1012@2|Bacteria,2IXFG@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Aldehyde dehydrogenase	-	-	-	ko:K04021	ko00620,ko01100,ko01120,map00620,map01100,map01120	-	R00228	RC00004,RC01195	ko00000,ko00001	-	-	-	Aldedh
YHH3_k127_1697461_3	382464.ABSI01000020_gene271	7.044e-186	586.0	COG1012@1|root,COG1012@2|Bacteria,46UYV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	-	ko:K04021	ko00620,ko01100,ko01120,map00620,map01100,map01120	-	R00228	RC00004,RC01195	ko00000,ko00001	-	-	-	Aldedh
YHH3_k127_1697461_15	382464.ABSI01000020_gene272	2.381e-31	124.0	COG4576@1|root,COG4576@2|Bacteria,46WVX@74201|Verrucomicrobia	74201|Verrucomicrobia	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
YHH3_k127_1697461_13	382464.ABSI01000020_gene273	4.856e-33	130.0	COG4576@1|root,COG4576@2|Bacteria,46WMY@74201|Verrucomicrobia	74201|Verrucomicrobia	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
YHH3_k127_1697461_2	382464.ABSI01000020_gene274	1.95e-189	595.0	COG0235@1|root,COG0235@2|Bacteria,46UR3@74201|Verrucomicrobia,2IVPG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
YHH3_k127_1697461_4	382464.ABSI01000020_gene275	1.844e-167	530.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,2ITGY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_1_C,Ldh_1_N
YHH3_k127_1697461_11	452637.Oter_1300	2.175e-39	152.0	COG1070@1|root,COG1070@2|Bacteria,46S5Z@74201|Verrucomicrobia,3K72U@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
YHH3_k127_1723608_5	1499967.BAYZ01000080_gene910	9.79e-05	51.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,ESPR,LVIVD,YadA_anchor,YadA_head,YadA_stalk
YHH3_k127_1723608_4	1396141.BATP01000040_gene2087	5.186e-09	66.0	COG2273@1|root,COG3209@1|root,COG4625@1|root,COG2273@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,DUF5011,He_PIG,Laminin_G_3,PATR,Phospholip_A2_3,RHS_repeat
YHH3_k127_1723608_3	502025.Hoch_0991	2.895e-14	78.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH3_k127_1723608_0	388413.ALPR1_02295	1.444e-176	569.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_1723608_1	1267535.KB906767_gene511	3.84e-154	500.0	COG3669@1|root,COG3669@2|Bacteria,3Y3J6@57723|Acidobacteria,2JKNJ@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
YHH3_k127_1723608_2	313628.LNTAR_05609	6.107e-152	490.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_1762719_2	452637.Oter_2836	1.621e-134	436.0	COG0541@1|root,COG0541@2|Bacteria,46SIU@74201|Verrucomicrobia,3K7HT@414999|Opitutae	414999|Opitutae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
YHH3_k127_1762719_3	452637.Oter_0632	3.922e-57	202.0	COG0432@1|root,COG0432@2|Bacteria,46V31@74201|Verrucomicrobia,3K83Z@414999|Opitutae	414999|Opitutae	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YHH3_k127_1762719_1	349741.Amuc_1068	8.548e-166	529.0	COG0192@1|root,COG0192@2|Bacteria,46S4V@74201|Verrucomicrobia,2ITRU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YHH3_k127_1762719_0	1396141.BATP01000059_gene2608	1.961e-252	784.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,2ITJN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
YHH3_k127_1762719_4	278957.ABEA03000017_gene2960	4.629e-36	145.0	COG2197@1|root,COG2197@2|Bacteria,46XU7@74201|Verrucomicrobia,3K85E@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_1762719_5	859657.RPSI07_mp1053	2.855e-10	64.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIWT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YHH3_k127_1769281_1	583355.Caka_1605	2.438e-38	151.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,3K75U@414999|Opitutae	414999|Opitutae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
YHH3_k127_1769281_4	452637.Oter_2586	1.826e-18	93.0	2E533@1|root,32ZW9@2|Bacteria,46SZX@74201|Verrucomicrobia,3K856@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1769281_0	452637.Oter_2777	6.797e-71	246.0	COG0353@1|root,COG0353@2|Bacteria,46SU3@74201|Verrucomicrobia,3K72H@414999|Opitutae	414999|Opitutae	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim,Toprim_4
YHH3_k127_1769281_3	583355.Caka_0266	3.741e-24	105.0	COG0718@1|root,COG0718@2|Bacteria,46TA9@74201|Verrucomicrobia,3K88P@414999|Opitutae	414999|Opitutae	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
YHH3_k127_1769281_2	1320556.AVBP01000009_gene2445	1.486e-37	148.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,43IN4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	amidohydrolase	hipO	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YHH3_k127_1792965_6	1150600.ADIARSV_1921	1.689e-27	113.0	COG1082@1|root,COG1082@2|Bacteria,4NIG9@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_1792965_4	1123242.JH636435_gene3087	1.293e-75	271.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	2|Bacteria	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_1792965_1	1304885.AUEY01000011_gene1774	1.15e-130	430.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,42Q2E@68525|delta/epsilon subdivisions,2WK17@28221|Deltaproteobacteria,2MMNU@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Inner membrane protein CreD	-	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
YHH3_k127_1792965_3	931276.Cspa_c41190	3.026e-100	342.0	COG1690@1|root,COG1690@2|Bacteria,1TPJ2@1239|Firmicutes,2481V@186801|Clostridia,36EU8@31979|Clostridiaceae	186801|Clostridia	S	tRNA-splicing ligase RtcB	-	-	-	-	-	-	-	-	-	-	-	-	RtcB,WYL
YHH3_k127_1792965_2	1121405.dsmv_3603	2.386e-106	351.0	COG2227@1|root,COG2227@2|Bacteria,1QZT3@1224|Proteobacteria,42QXG@68525|delta/epsilon subdivisions,2WMWI@28221|Deltaproteobacteria,2MJJJ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH3_k127_1792965_5	756272.Plabr_2598	1.91e-46	173.0	COG3651@1|root,COG3651@2|Bacteria,2IZXW@203682|Planctomycetes	203682|Planctomycetes	S	protein conserved in bacteria	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
YHH3_k127_1792965_0	869213.JCM21142_41996	1.013e-174	561.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47M69@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_1794029_0	1120999.JONM01000005_gene3832	5.558e-142	480.0	28KDG@1|root,2Z9ZZ@2|Bacteria,1R86C@1224|Proteobacteria,2W193@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1813974_0	1047013.AQSP01000120_gene936	0.0	1038.0	COG4354@1|root,COG4354@2|Bacteria,2NQ9B@2323|unclassified Bacteria	2|Bacteria	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,Glyco_hydr_116N
YHH3_k127_1813974_2	1123070.KB899261_gene2142	1.182e-131	432.0	28HII@1|root,2Z7TZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1813974_5	926556.Echvi_0508	7.191e-112	375.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,47JBN@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
YHH3_k127_1813974_1	411479.BACUNI_00171	4.291e-159	525.0	COG4030@1|root,COG4030@2|Bacteria,4NIPI@976|Bacteroidetes,2FRFX@200643|Bacteroidia,4AMYU@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG11699 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
YHH3_k127_1813974_4	1286632.P278_33300	8.221e-113	381.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1HX8I@117743|Flavobacteriia	976|Bacteroidetes	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
YHH3_k127_1813974_3	1304880.JAGB01000001_gene487	2.36e-119	396.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,249GP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
YHH3_k127_1813974_6	313628.LNTAR_17788	2.185e-48	179.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,Peptidase_S9
YHH3_k127_1827282_0	880073.Calab_0643	2.051e-92	313.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH3_k127_1827282_1	604354.TSIB_0629	3.406e-77	267.0	COG1180@1|root,arCOG00952@2157|Archaea,2XZW0@28890|Euryarchaeota,244ZY@183968|Thermococci	183968|Thermococci	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
YHH3_k127_1837371_0	583355.Caka_2039	0.0	1055.0	COG0249@1|root,COG0249@2|Bacteria,46SCK@74201|Verrucomicrobia,3K7NX@414999|Opitutae	414999|Opitutae	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
YHH3_k127_1837371_1	452637.Oter_3762	1.328e-20	93.0	COG0596@1|root,COG0596@2|Bacteria,46V2G@74201|Verrucomicrobia,3K86K@414999|Opitutae	414999|Opitutae	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YHH3_k127_1838830_2	1121904.ARBP01000011_gene1568	2.449e-53	190.0	COG1063@1|root,COG1063@2|Bacteria,4NJW8@976|Bacteroidetes,47M9A@768503|Cytophagia	976|Bacteroidetes	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_1838830_0	1121904.ARBP01000011_gene1569	8.912e-124	404.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,47JQN@768503|Cytophagia	976|Bacteroidetes	G	PFAM Transketolase, C-terminal domain	tktC	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
YHH3_k127_1838830_1	1121472.AQWN01000008_gene2037	2.821e-96	324.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2607I@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YHH3_k127_18585_1	926551.KB900719_gene291	2.114e-44	184.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,1HZYU@117743|Flavobacteriia,1ER0M@1016|Capnocytophaga	976|Bacteroidetes	G	F5 8 type C domain protein	fucA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc
YHH3_k127_18585_0	1358423.N180_07365	5.982e-156	516.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IRC7@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_1879636_4	583355.Caka_1162	9.216e-58	207.0	COG0036@1|root,COG0036@2|Bacteria,46TEK@74201|Verrucomicrobia,3K7FI@414999|Opitutae	414999|Opitutae	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YHH3_k127_1879636_3	452637.Oter_3602	1.943e-63	230.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,3K7IV@414999|Opitutae	414999|Opitutae	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_6
YHH3_k127_1879636_1	382464.ABSI01000010_gene3377	1.847e-123	404.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia,2ITMR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
YHH3_k127_1879636_2	382464.ABSI01000010_gene3376	1.291e-108	363.0	COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia,2ITU1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
YHH3_k127_1879636_5	583355.Caka_2951	4.807e-25	104.0	COG0333@1|root,COG0333@2|Bacteria,46WWH@74201|Verrucomicrobia,3K8FQ@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
YHH3_k127_1879636_6	278957.ABEA03000087_gene604	1.974e-14	83.0	2F739@1|root,33ZIU@2|Bacteria,46VU4@74201|Verrucomicrobia,3K808@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1879636_0	794903.OPIT5_10610	4.416e-160	511.0	COG0082@1|root,COG0082@2|Bacteria,46SEA@74201|Verrucomicrobia,3K7DA@414999|Opitutae	414999|Opitutae	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
YHH3_k127_1908759_2	382464.ABSI01000023_gene598	7.838e-101	334.0	COG1363@1|root,COG1363@2|Bacteria,46SM3@74201|Verrucomicrobia,2IU2V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
YHH3_k127_1908759_1	382464.ABSI01000005_gene1217	2.854e-174	556.0	COG1219@1|root,COG1219@2|Bacteria,46SIK@74201|Verrucomicrobia,2ITIB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
YHH3_k127_1908759_3	583355.Caka_0725	1.126e-93	312.0	COG0740@1|root,COG0740@2|Bacteria,46SAB@74201|Verrucomicrobia,3K7Q1@414999|Opitutae	414999|Opitutae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YHH3_k127_1908759_5	382464.ABSI01000005_gene1215	3.934e-67	240.0	COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia,2ITGE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YHH3_k127_1908759_7	583355.Caka_0726	4.98e-26	112.0	COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia,3K7I6@414999|Opitutae	414999|Opitutae	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
YHH3_k127_1908759_0	571166.KI421509_gene1184	8.71e-176	573.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YHH3_k127_1908759_4	583355.Caka_1702	5.329e-80	277.0	COG1131@1|root,COG1131@2|Bacteria,46V0T@74201|Verrucomicrobia,3K9MC@414999|Opitutae	414999|Opitutae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_1908759_6	583355.Caka_1703	3.6e-40	157.0	2C37Z@1|root,33NYZ@2|Bacteria,46UEA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1914573_1	278957.ABEA03000060_gene3117	2.509e-92	311.0	COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,3K7D5@414999|Opitutae	414999|Opitutae	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
YHH3_k127_1914573_0	583355.Caka_0836	5.817e-128	415.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia,3K75G@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_1914573_3	452637.Oter_1688	5.328e-77	272.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	cpg2	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
YHH3_k127_1914573_2	523791.Kkor_0787	3.477e-79	276.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,1XHNI@135619|Oceanospirillales	135619|Oceanospirillales	E	arginine N-succinyltransferase	-	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	AstA
YHH3_k127_1914573_4	400668.Mmwyl1_3670	1.65e-10	64.0	COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1XHCT@135619|Oceanospirillales	135619|Oceanospirillales	C	Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate	astD	-	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
YHH3_k127_191535_1	382464.ABSI01000011_gene3153	1.69e-203	640.0	COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,2ITMG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Anticodon binding domain	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
YHH3_k127_191535_3	1127673.GLIP_1568	1.839e-29	125.0	COG3832@1|root,COG3832@2|Bacteria,1RDGX@1224|Proteobacteria,1S4FQ@1236|Gammaproteobacteria,4675R@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
YHH3_k127_191535_2	583355.Caka_1835	1.435e-176	570.0	COG0608@1|root,COG0608@2|Bacteria,46SNV@74201|Verrucomicrobia,3K747@414999|Opitutae	414999|Opitutae	L	exonuclease RecJ	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH3_k127_191535_0	583355.Caka_1836	1.204e-252	806.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,3K770@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
YHH3_k127_193075_2	452637.Oter_1455	9.67e-11	65.0	COG0845@1|root,COG0845@2|Bacteria,46US2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YHH3_k127_193075_0	1121396.KB893066_gene1580	0.0	1403.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,2MIUG@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_193075_1	1231185.BAMP01000004_gene3788	1.595e-73	254.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,43H60@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YHH3_k127_1942434_8	583355.Caka_1045	3.679e-57	206.0	COG0491@1|root,COG0491@2|Bacteria,46T2E@74201|Verrucomicrobia,3K7YR@414999|Opitutae	414999|Opitutae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH3_k127_1942434_3	794903.OPIT5_18120	9.044e-105	351.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,46UA0@74201|Verrucomicrobia,3K7GI@414999|Opitutae	414999|Opitutae	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
YHH3_k127_1942434_9	583355.Caka_3036	6.653e-52	191.0	COG0127@1|root,COG0127@2|Bacteria,46VGG@74201|Verrucomicrobia,3K87U@414999|Opitutae	414999|Opitutae	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
YHH3_k127_1942434_1	452637.Oter_3652	4.888e-126	411.0	COG0761@1|root,COG0761@2|Bacteria,46SYM@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
YHH3_k127_1942434_0	497964.CfE428DRAFT_0727	4.707e-211	671.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,46UC6@74201|Verrucomicrobia	74201|Verrucomicrobia	C	IMP dehydrogenase GMP reductase	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
YHH3_k127_1942434_7	46234.ANA_C12889	1.529e-57	218.0	COG0318@1|root,COG0318@2|Bacteria,1G2RA@1117|Cyanobacteria,1HJMW@1161|Nostocales	1117|Cyanobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.menE	AMP-binding,AMP-binding_C
YHH3_k127_1942434_11	197221.22294898	4.457e-40	162.0	COG4948@1|root,COG4948@2|Bacteria,1G0R5@1117|Cyanobacteria	1117|Cyanobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C
YHH3_k127_1942434_2	1123070.KB899259_gene2015	4.17e-121	400.0	COG0399@1|root,COG0399@2|Bacteria,46SEI@74201|Verrucomicrobia,2ITTP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH3_k127_1942434_5	1137799.GZ78_24145	1.73e-81	278.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,1XJ87@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
YHH3_k127_1942434_4	583355.Caka_2953	5.667e-103	344.0	COG1968@1|root,COG1968@2|Bacteria,46SP6@74201|Verrucomicrobia,3K7D8@414999|Opitutae	414999|Opitutae	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
YHH3_k127_1942434_6	794903.OPIT5_11015	1.301e-58	213.0	COG0600@1|root,COG0600@2|Bacteria,46Y5C@74201|Verrucomicrobia,3K8YK@414999|Opitutae	414999|Opitutae	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
YHH3_k127_1942434_10	1046714.AMRX01000001_gene1431	2.178e-43	162.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,1RRG7@1236|Gammaproteobacteria,46AUI@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
YHH3_k127_1950437_2	382464.ABSI01000012_gene2012	9.121e-26	110.0	COG1629@1|root,COG1629@2|Bacteria,46U2X@74201|Verrucomicrobia	74201|Verrucomicrobia	M	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_1950437_0	1123070.KB899262_gene1687	1.73e-150	502.0	COG4585@1|root,COG4585@2|Bacteria,46X8Q@74201|Verrucomicrobia,2IUG0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,HATPase_c,HisKA_3
YHH3_k127_1950437_1	1123070.KB899262_gene1702	1.065e-39	152.0	COG2197@1|root,COG2197@2|Bacteria,46XIF@74201|Verrucomicrobia,2IW0D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_1955105_2	886293.Sinac_1154	1.203e-31	124.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YHH3_k127_1955105_1	886293.Sinac_1155	1.05e-130	433.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
YHH3_k127_1955105_0	452637.Oter_0974	1.145e-174	558.0	28K42@1|root,2Z9T6@2|Bacteria,46TUF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
YHH3_k127_1977865_2	305700.B447_20900	4.96e-72	245.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,2VQ8E@28216|Betaproteobacteria,2KYRU@206389|Rhodocyclales	206389|Rhodocyclales	S	Flavodoxin-like fold	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
YHH3_k127_1977865_1	880073.Calab_1405	3.423e-96	327.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_1977865_5	1266925.JHVX01000008_gene327	1.688e-29	121.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,3727A@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
YHH3_k127_1977865_3	1123234.AUKI01000011_gene1292	4.198e-52	187.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
YHH3_k127_1977865_0	382464.ABSI01000011_gene2354	4.338e-117	381.0	COG0695@1|root,COG0695@2|Bacteria,46XX2@74201|Verrucomicrobia,2IVIC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
YHH3_k127_1977865_4	1121918.ARWE01000001_gene2179	6.129e-38	148.0	2ED7H@1|root,33743@2|Bacteria,1NA6E@1224|Proteobacteria,42V2U@68525|delta/epsilon subdivisions,2WS45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1977865_6	595460.RRSWK_04026	1.568e-07	54.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
YHH3_k127_1985859_3	335543.Sfum_3861	6.915e-44	162.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42NJU@68525|delta/epsilon subdivisions,2X9WU@28221|Deltaproteobacteria,2MRQN@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_1985859_0	1280674.AUJK01000022_gene243	5.884e-116	403.0	COG0515@1|root,COG5492@1|root,COG0515@2|Bacteria,COG5492@2|Bacteria,4NIPJ@976|Bacteroidetes,2FR2K@200643|Bacteroidia	976|Bacteroidetes	N	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,Pkinase
YHH3_k127_1985859_1	1160721.RBI_I00579	3.334e-91	325.0	COG3209@1|root,COG5492@1|root,COG3209@2|Bacteria,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,3WGX5@541000|Ruminococcaceae	186801|Clostridia	N	dockerin type I repeat-containing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LRR_5
YHH3_k127_1985859_4	76114.ebA5197	3.15e-12	70.0	COG0840@1|root,COG0840@2|Bacteria,1QVIE@1224|Proteobacteria,2WGSN@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
YHH3_k127_1985859_5	713586.KB900536_gene333	2.195e-09	64.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,1T20E@1236|Gammaproteobacteria,1X2SH@135613|Chromatiales	135613|Chromatiales	G	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
YHH3_k127_1985859_2	583355.Caka_1487	6.691e-66	229.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH3_k127_1987484_0	1322246.BN4_20129	1.3e-316	999.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MG2T@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_1987484_2	756272.Plabr_3087	2.953e-54	207.0	COG0845@1|root,COG0845@2|Bacteria,2J26G@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
YHH3_k127_1987484_1	1121441.AUCX01000005_gene1396	9.372e-80	284.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MU2@68525|delta/epsilon subdivisions,2WMYH@28221|Deltaproteobacteria,2MGXV@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_200696_4	1121904.ARBP01000029_gene2184	2.223e-64	229.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
YHH3_k127_200696_1	521674.Plim_0046	1.365e-80	273.0	COG1413@1|root,COG1413@2|Bacteria,2IX4C@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_200696_3	880073.Calab_1627	3.269e-75	256.0	COG4577@1|root,COG4577@2|Bacteria,2NRES@2323|unclassified Bacteria	2|Bacteria	CQ	BMC	-	-	-	ko:K04025	-	-	-	-	ko00000	-	-	-	BMC
YHH3_k127_200696_0	880073.Calab_1626	2.215e-181	578.0	COG4656@1|root,COG4656@2|Bacteria,2NQD0@2323|unclassified Bacteria	2|Bacteria	C	RnfC Barrel sandwich hybrid domain	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
YHH3_k127_200696_2	349521.HCH_00950	2.158e-77	267.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
YHH3_k127_200696_5	1089553.Tph_c09100	1.14e-49	184.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,42G9W@68295|Thermoanaerobacterales	186801|Clostridia	H	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
YHH3_k127_201695_0	583355.Caka_0651	8.958e-208	662.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,46UJK@74201|Verrucomicrobia,3K9E7@414999|Opitutae	414999|Opitutae	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
YHH3_k127_2045283_0	305900.GV64_21710	4.611e-60	227.0	COG5492@1|root,COG5492@2|Bacteria,1QYMJ@1224|Proteobacteria,1SHZW@1236|Gammaproteobacteria	2|Bacteria	N	Polysaccharide lyase family 8, C-terminal beta-sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF5011,Laminin_G_3,Lyase_8,Lyase_8_C,Lyase_8_N,Lyase_catalyt,Sulfatase
YHH3_k127_2070048_0	583355.Caka_1593	3.942e-09	66.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329,MucB_RseB,Sigma70_r2,Sigma70_r4_2
YHH3_k127_2084308_0	595460.RRSWK_05939	1.012e-176	564.0	COG3119@1|root,COG3119@2|Bacteria,2J2PQ@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_2084308_1	1121904.ARBP01000011_gene1477	1.426e-62	222.0	COG1082@1|root,COG1082@2|Bacteria,4NIG9@976|Bacteroidetes,47NIT@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_2097026_0	1353537.TP2_00585	0.0	1412.0	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG4625@1|root,COG4935@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria,COG4935@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,DUF4214,HemolysinCabind,Hint_2
YHH3_k127_2101951_3	944547.ABLL_2230	3.314e-27	115.0	COG4875@1|root,COG4875@2|Bacteria,1RFS2@1224|Proteobacteria,43B6N@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
YHH3_k127_2101951_2	225849.swp_3822	8.486e-91	303.0	COG0670@1|root,COG0670@2|Bacteria,1MVGU@1224|Proteobacteria,1RNKB@1236|Gammaproteobacteria,2Q8Z5@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
YHH3_k127_2101951_0	382464.ABSI01000011_gene2998	1.255e-122	401.0	COG0385@1|root,COG0385@2|Bacteria,46YXM@74201|Verrucomicrobia,2IU81@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SBF-like CPA transporter family (DUF4137)	-	-	-	-	-	-	-	-	-	-	-	-	SBF
YHH3_k127_2101951_1	313628.LNTAR_07789	1.719e-101	341.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	suhB	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
YHH3_k127_2110230_0	293826.Amet_2984	7.945e-70	247.0	COG0305@1|root,COG0305@2|Bacteria,1UJC1@1239|Firmicutes,25F1B@186801|Clostridia	186801|Clostridia	L	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
YHH3_k127_2122338_6	497964.CfE428DRAFT_6195	9.627e-27	112.0	COG0673@1|root,COG0673@2|Bacteria,46UE3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_2122338_1	926550.CLDAP_34560	2.775e-130	422.0	COG1082@1|root,COG1082@2|Bacteria,2G6W6@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
YHH3_k127_2122338_3	1185876.BN8_03075	5.587e-109	366.0	COG4948@1|root,COG4948@2|Bacteria,4NKDF@976|Bacteroidetes,47U6R@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
YHH3_k127_2122338_4	521674.Plim_0354	2.802e-90	325.0	COG3119@1|root,COG3119@2|Bacteria,2IWX1@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
YHH3_k127_2122338_0	756272.Plabr_3164	8.382e-248	778.0	COG3119@1|root,COG3119@2|Bacteria,2J1R8@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_2122338_2	1123242.JH636434_gene3911	3.487e-118	389.0	COG1957@1|root,COG1957@2|Bacteria,2IYE3@203682|Planctomycetes	203682|Planctomycetes	F	COG1957 Inosine-uridine nucleoside N-ribohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
YHH3_k127_2122338_5	886293.Sinac_0540	6.807e-33	128.0	COG0279@1|root,COG0279@2|Bacteria,2IZQU@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
YHH3_k127_2125631_0	715451.ambt_18920	1.023e-18	100.0	2C5Z1@1|root,33ZHM@2|Bacteria,1NXTS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2126803_0	452637.Oter_3724	2.482e-205	645.0	COG0017@1|root,COG0017@2|Bacteria	2|Bacteria	J	Asparaginyl-tRNA synthetase	asnS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSDY_1059.SDY_2327	tRNA-synt_2,tRNA_anti-codon
YHH3_k127_2126803_1	583355.Caka_2531	1.009e-25	109.0	COG0695@1|root,COG0695@2|Bacteria,46TC3@74201|Verrucomicrobia,3K8HC@414999|Opitutae	414999|Opitutae	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
YHH3_k127_2126803_2	1380600.AUYN01000001_gene2371	5.732e-07	51.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1HXMR@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH3_k127_2128666_2	713586.KB900536_gene1232	0.0001273	45.0	2ECCV@1|root,336B4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
YHH3_k127_2128666_0	1396141.BATP01000032_gene4318	1.698e-17	97.0	2BHNH@1|root,32BRD@2|Bacteria,46Z4Q@74201|Verrucomicrobia,2IUDY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2128666_1	1499967.BAYZ01000090_gene4954	7.273e-11	68.0	COG0500@1|root,COG2226@2|Bacteria,2NQZU@2323|unclassified Bacteria	2|Bacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
YHH3_k127_216377_3	756272.Plabr_2347	5.165e-95	319.0	COG1063@1|root,COG1063@2|Bacteria,2J0AD@203682|Planctomycetes	203682|Planctomycetes	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_216377_2	1396141.BATP01000042_gene1903	8.838e-122	396.0	COG1028@1|root,COG1028@2|Bacteria,46U4E@74201|Verrucomicrobia,2IV1N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH3_k127_216377_1	929562.Emtol_1373	1.024e-132	433.0	COG3828@1|root,COG3828@2|Bacteria,4NFMU@976|Bacteroidetes,47K27@768503|Cytophagia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
YHH3_k127_216377_0	452637.Oter_2482	7.884e-203	651.0	COG0673@1|root,COG1082@1|root,COG0673@2|Bacteria,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_216377_4	452637.Oter_2603	1.489e-87	290.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
YHH3_k127_2184504_4	595460.RRSWK_03838	1.172e-77	263.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	1.6.5.3,3.4.21.107	ko:K00337,ko:K04771	ko00190,ko01100,ko01503,ko02020,map00190,map01100,map01503,map02020	M00144,M00728	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	3.D.1	-	-	NADHdh,PDZ_2,Trypsin_2
YHH3_k127_2184504_0	616991.JPOO01000003_gene1607	3.047e-290	929.0	COG3119@1|root,COG3119@2|Bacteria,4NE9D@976|Bacteroidetes,1HY4G@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_2184504_1	595460.RRSWK_03839	7.507e-252	817.0	COG3669@1|root,COG3669@2|Bacteria,2J4D6@203682|Planctomycetes	203682|Planctomycetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
YHH3_k127_2184504_2	313628.LNTAR_22879	1.48e-145	492.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06889,ko:K07214	-	-	-	-	ko00000	-	-	-	AXE1,Abhydrolase_1,Esterase,Lipase_GDSL_2,Peptidase_S9
YHH3_k127_2184504_3	1250005.PHEL85_2004	9.467e-105	371.0	2DBE9@1|root,2Z8RI@2|Bacteria,4P09I@976|Bacteroidetes,1I8I3@117743|Flavobacteriia	976|Bacteroidetes	S	Hypothetical glycosyl hydrolase family 15	-	-	-	-	-	-	-	-	-	-	-	-	GHL15
YHH3_k127_2184504_5	595460.RRSWK_04294	9.933e-21	108.0	COG1621@1|root,COG1621@2|Bacteria	595460.RRSWK_04294|-	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2187174_0	382464.ABSI01000002_gene4374	1.163e-277	861.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH3_k127_2187174_1	382464.ABSI01000002_gene4373	2.24e-228	714.0	COG4656@1|root,COG4656@2|Bacteria,46W83@74201|Verrucomicrobia	74201|Verrucomicrobia	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
YHH3_k127_2187174_2	382464.ABSI01000002_gene4372	6.74e-156	498.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	rnfD	-	1.6.5.8	ko:K00347,ko:K03614	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
YHH3_k127_2187174_6	382464.ABSI01000002_gene4371	2.585e-64	229.0	COG4659@1|root,COG4659@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
YHH3_k127_2187174_4	382464.ABSI01000002_gene4370	4.49e-111	362.0	COG4660@1|root,COG4660@2|Bacteria	2|Bacteria	C	electron transport chain	rnfE	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944	2.3.1.243,4.2.99.18	ko:K02560,ko:K03613,ko:K10773	ko00540,ko01100,ko03410,map00540,map01100,map03410	M00060	R05075	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005,ko03400	-	-	-	Rnf-Nqr
YHH3_k127_2187174_5	870187.Thini_2679	7.958e-81	273.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,4604J@72273|Thiotrichales	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
YHH3_k127_2187174_3	382464.ABSI01000002_gene4368	4.89e-127	411.0	COG0369@1|root,COG0369@2|Bacteria	2|Bacteria	C	hydroxylamine reductase activity	petH	GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464	1.14.13.208,1.18.1.2,1.19.1.1	ko:K00528,ko:K02287,ko:K02641,ko:K15511	ko00195,ko00196,ko00362,ko01100,map00195,map00196,map00362,map01100	-	R09555,R10159	RC01739	ko00000,ko00001,ko00194,ko01000	-	-	iJN678.petH	CpcD,FAD_binding_6,Fer4,NAD_binding_1
YHH3_k127_2187174_7	382464.ABSI01000007_gene4095	3.296e-22	99.0	COG0679@1|root,COG0679@2|Bacteria,46SPM@74201|Verrucomicrobia,2IUBD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
YHH3_k127_219326_3	794903.OPIT5_01645	3.415e-23	101.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia,3K793@414999|Opitutae	414999|Opitutae	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
YHH3_k127_219326_0	583355.Caka_1050	1.803e-141	458.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia,3K761@414999|Opitutae	414999|Opitutae	C	AAA domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
YHH3_k127_219326_4	1156844.KB891849_gene3382	0.0005006	48.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
YHH3_k127_219326_2	382464.ABSI01000012_gene2239	1.079e-68	253.0	COG0784@1|root,COG2208@1|root,COG0784@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	DUF4388,PAS,PAS_9,Response_reg,SpoIIE
YHH3_k127_219326_1	583355.Caka_0712	1.726e-102	345.0	COG0617@1|root,COG0617@2|Bacteria,46UER@74201|Verrucomicrobia,3K732@414999|Opitutae	414999|Opitutae	J	Polynucleotide adenylyltransferase	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
YHH3_k127_2206913_1	756272.Plabr_2856	1.017e-116	391.0	COG3119@1|root,COG3119@2|Bacteria,2IXIB@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_2206913_5	391603.FBALC1_14522	3.55e-05	51.0	COG3291@1|root,COG3291@2|Bacteria,4NHC7@976|Bacteroidetes,1HX8W@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4886)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4886
YHH3_k127_2206913_4	1150600.ADIARSV_2631	9.37e-78	270.0	COG0584@1|root,COG0584@2|Bacteria,4NE2E@976|Bacteroidetes,1IRVM@117747|Sphingobacteriia	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF4996,GDPD
YHH3_k127_2206913_3	180332.JTGN01000005_gene2930	5.316e-82	292.0	COG3669@1|root,COG3669@2|Bacteria,1U9XH@1239|Firmicutes,24DER@186801|Clostridia	186801|Clostridia	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
YHH3_k127_2206913_2	189753.AXAS01000009_gene6315	1.478e-100	345.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,3JXU5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_2206913_0	595460.RRSWK_00740	1.313e-140	455.0	COG2610@1|root,COG2610@2|Bacteria	2|Bacteria	EG	gluconate transmembrane transporter activity	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
YHH3_k127_2250435_0	1123508.JH636441_gene3126	2.613e-104	348.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_2250435_1	886293.Sinac_2838	4.454e-100	340.0	COG0673@1|root,COG0673@2|Bacteria,2IY5Y@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_2270569_2	1229276.DI53_2523	3.861e-06	51.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1IQ0R@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	aslA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_2270569_3	1307761.L21SP2_0748	0.0001924	46.0	COG2939@1|root,COG2939@2|Bacteria	2|Bacteria	E	PFAM Peptidase S10, serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
YHH3_k127_2270569_1	997884.HMPREF1068_01321	1.477e-06	61.0	COG1595@1|root,COG2755@1|root,COG5498@1|root,COG1595@2|Bacteria,COG2755@2|Bacteria,COG5498@2|Bacteria,4NIIW@976|Bacteroidetes,2FRB8@200643|Bacteroidia,4AMKC@815|Bacteroidaceae	976|Bacteroidetes	K	GxGYxY sequence motif in domain of unknown function N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,GxGYxYP_C,GxGYxYP_N,RicinB_lectin_2
YHH3_k127_2270569_0	1246995.AFR_21905	9.059e-11	75.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,4D8ZF@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
YHH3_k127_2293359_5	583355.Caka_1042	2.616e-52	190.0	COG0431@1|root,COG0431@2|Bacteria,46SXE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
YHH3_k127_2293359_7	1111728.ATYS01000015_gene4722	1.282e-13	79.0	2C60Y@1|root,32YTG@2|Bacteria,1NCUM@1224|Proteobacteria,1SDA6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2293359_6	452637.Oter_2376	1.329e-46	175.0	COG1443@1|root,COG1443@2|Bacteria,46T1S@74201|Verrucomicrobia,3K84X@414999|Opitutae	414999|Opitutae	I	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH3_k127_2293359_3	204669.Acid345_4407	4.397e-85	290.0	COG1611@1|root,COG1611@2|Bacteria,3Y2MR@57723|Acidobacteria,2JHUP@204432|Acidobacteriia	204432|Acidobacteriia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH3_k127_2293359_1	1123236.KB899388_gene2111	3.978e-167	548.0	COG0427@1|root,COG1247@1|root,COG0427@2|Bacteria,COG1247@2|Bacteria,1MUGE@1224|Proteobacteria,1RP19@1236|Gammaproteobacteria,46429@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	acetyl-CoA hydrolase	-	-	-	ko:K18288	ko00660,map00660	-	R02407,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
YHH3_k127_2293359_4	583355.Caka_1716	2.423e-61	217.0	COG0500@1|root,COG2226@2|Bacteria,46V7S@74201|Verrucomicrobia,3K7ZC@414999|Opitutae	414999|Opitutae	Q	PFAM Methionine biosynthesis MetW protein	-	-	-	-	-	-	-	-	-	-	-	-	MetW
YHH3_k127_2293359_2	794903.OPIT5_09495	1.609e-164	525.0	COG2021@1|root,COG2021@2|Bacteria,46U58@74201|Verrucomicrobia,3K7TJ@414999|Opitutae	414999|Opitutae	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
YHH3_k127_2293359_0	583355.Caka_2311	1.015e-194	617.0	COG0015@1|root,COG0015@2|Bacteria,46U88@74201|Verrucomicrobia,3K7I7@414999|Opitutae	414999|Opitutae	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
YHH3_k127_2318061_6	313628.LNTAR_09771	3.648e-22	101.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_2318061_3	1123242.JH636436_gene545	8.87e-111	375.0	COG3119@1|root,COG3119@2|Bacteria,2IYSH@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_2318061_4	756272.Plabr_2974	2.145e-98	337.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_2318061_1	344747.PM8797T_19819	1.585e-138	459.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_2318061_0	313628.LNTAR_09629	1.173e-170	548.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_2318061_5	1432056.X781_19450	1.979e-45	178.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1Y6VY@135625|Pasteurellales	135625|Pasteurellales	K	Ribose operon repressor	rbsR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
YHH3_k127_2318061_2	880073.Calab_0640	5.258e-115	383.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_2374470_4	1406840.Q763_15825	2.225e-05	51.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1I34F@117743|Flavobacteriia,2NWHP@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
YHH3_k127_2374470_2	583355.Caka_1842	3.73e-102	343.0	COG1208@1|root,COG1208@2|Bacteria,46UYH@74201|Verrucomicrobia,3K75K@414999|Opitutae	414999|Opitutae	JM	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
YHH3_k127_2374470_0	382464.ABSI01000011_gene2821	1.579e-136	442.0	COG4608@1|root,COG4608@2|Bacteria,46U8E@74201|Verrucomicrobia,2ITPK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
YHH3_k127_2374470_1	278957.ABEA03000201_gene4325	2.563e-131	428.0	COG0444@1|root,COG4608@1|root,COG0444@2|Bacteria,COG4608@2|Bacteria,46U8E@74201|Verrucomicrobia,3KA26@414999|Opitutae	414999|Opitutae	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
YHH3_k127_2374470_3	566466.NOR53_421	2.189e-17	83.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1J88U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
YHH3_k127_2376391_5	382464.ABSI01000011_gene2767	3.383e-58	204.0	COG0493@1|root,COG0493@2|Bacteria,46T1M@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltD	-	1.3.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	M00046	R00093,R00114,R00248,R00977,R01414,R11026	RC00006,RC00010,RC00072,RC00123,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
YHH3_k127_2376391_2	377629.TERTU_3393	7.55e-87	303.0	COG1482@1|root,COG1482@2|Bacteria,1MUD8@1224|Proteobacteria,1RQX8@1236|Gammaproteobacteria,2PP7Z@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Phosphomannose isomerase type I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
YHH3_k127_2376391_0	583355.Caka_1345	1.659e-249	794.0	COG1204@1|root,COG1204@2|Bacteria,46SCW@74201|Verrucomicrobia,3K8N5@414999|Opitutae	414999|Opitutae	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
YHH3_k127_2376391_4	583355.Caka_1203	1.984e-76	266.0	COG4608@1|root,COG4608@2|Bacteria,46SHJ@74201|Verrucomicrobia,3K7GF@414999|Opitutae	414999|Opitutae	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
YHH3_k127_2376391_1	452637.Oter_0629	1.487e-118	391.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,46S8G@74201|Verrucomicrobia,3K7IY@414999|Opitutae	414999|Opitutae	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
YHH3_k127_2376391_6	583355.Caka_1946	1.074e-47	181.0	COG1652@1|root,COG1652@2|Bacteria,46T8E@74201|Verrucomicrobia,3K82V@414999|Opitutae	414999|Opitutae	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
YHH3_k127_2376391_3	794903.OPIT5_00545	9.122e-84	291.0	COG1104@1|root,COG1104@2|Bacteria,46SFF@74201|Verrucomicrobia,3K7PX@414999|Opitutae	414999|Opitutae	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YHH3_k127_2379776_1	479437.Elen_2127	1.507e-94	317.0	COG0330@1|root,COG0330@2|Bacteria,2GM0Z@201174|Actinobacteria,4CUCE@84998|Coriobacteriia	84998|Coriobacteriia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH3_k127_2379776_3	1150600.ADIARSV_4201	4.818e-13	70.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,1IUPB@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
YHH3_k127_2379776_0	583355.Caka_1877	9.456e-205	649.0	COG0104@1|root,COG0104@2|Bacteria,46TDF@74201|Verrucomicrobia,3K7KQ@414999|Opitutae	414999|Opitutae	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
YHH3_k127_2379776_2	583355.Caka_1909	1.578e-38	147.0	COG1109@1|root,COG1109@2|Bacteria,46SB1@74201|Verrucomicrobia,3K7CC@414999|Opitutae	414999|Opitutae	G	PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
YHH3_k127_2384889_6	1122214.AQWH01000002_gene4159	9.757e-40	154.0	COG0673@1|root,COG0673@2|Bacteria,1PHFG@1224|Proteobacteria,2V8DX@28211|Alphaproteobacteria,2PMAY@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_2384889_4	1347342.BN863_19230	8.351e-57	206.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
YHH3_k127_2384889_2	143224.JQMD01000002_gene2461	6.058e-94	318.0	COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,1I3V7@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,DUF1080
YHH3_k127_2384889_3	595460.RRSWK_00752	1.289e-76	268.0	COG1082@1|root,COG1082@2|Bacteria,2IYUT@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_2384889_8	391616.OA238_c14250	1.588e-30	128.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
YHH3_k127_2384889_9	338963.Pcar_1474	8.161e-14	78.0	COG0457@1|root,COG0457@2|Bacteria,1QY6N@1224|Proteobacteria,42XBU@68525|delta/epsilon subdivisions,2WT6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2384889_5	1419583.V466_14155	1.014e-45	169.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,1S6K5@1236|Gammaproteobacteria,1YTPH@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
YHH3_k127_2384889_0	589865.DaAHT2_1401	8.481e-136	443.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42NT1@68525|delta/epsilon subdivisions,2WKDE@28221|Deltaproteobacteria,2MPYW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_2384889_11	720555.BATR1942_00375	2.366e-06	57.0	COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HB5I@91061|Bacilli,1ZF99@1386|Bacillus	91061|Bacilli	M	Glycosyl hydrolase	ydhD	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM
YHH3_k127_2384889_7	583355.Caka_1103	2.158e-35	142.0	COG0494@1|root,COG0494@2|Bacteria,46VG9@74201|Verrucomicrobia,3K81U@414999|Opitutae	414999|Opitutae	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH3_k127_2384889_1	794903.OPIT5_18050	1.617e-94	328.0	COG0534@1|root,COG0534@2|Bacteria,46UTM@74201|Verrucomicrobia,3K890@414999|Opitutae	414999|Opitutae	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
YHH3_k127_2412495_2	583355.Caka_0440	3.444e-86	294.0	COG0491@1|root,COG0491@2|Bacteria,46S7X@74201|Verrucomicrobia,3K7J6@414999|Opitutae	414999|Opitutae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH3_k127_2412495_3	382464.ABSI01000010_gene3225	3.45e-74	264.0	COG0845@1|root,COG0845@2|Bacteria,46VEA@74201|Verrucomicrobia,2IUBR@203494|Verrucomicrobiae	74201|Verrucomicrobia	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
YHH3_k127_2412495_0	382464.ABSI01000010_gene3226	0.0	1189.0	COG0841@1|root,COG0841@2|Bacteria,46UEW@74201|Verrucomicrobia,2IV6M@203494|Verrucomicrobiae	2|Bacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_2412495_5	583355.Caka_0774	5.222e-30	132.0	COG0226@1|root,COG0226@2|Bacteria,46XUS@74201|Verrucomicrobia,3K8AS@414999|Opitutae	414999|Opitutae	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
YHH3_k127_2412495_7	1158182.KB905020_gene1911	3.768e-14	75.0	COG1872@1|root,COG1872@2|Bacteria,1QKJ0@1224|Proteobacteria,1SDPY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
YHH3_k127_2412495_1	452637.Oter_3022	5.098e-121	398.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,46U8V@74201|Verrucomicrobia,3K7U6@414999|Opitutae	414999|Opitutae	E	Prephenate dehydratase	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
YHH3_k127_2412495_4	583355.Caka_2329	3.258e-72	252.0	COG1386@1|root,COG1386@2|Bacteria,46V9G@74201|Verrucomicrobia,3K7RR@414999|Opitutae	414999|Opitutae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
YHH3_k127_2412495_6	583355.Caka_2326	1.085e-25	110.0	COG0166@1|root,COG0166@2|Bacteria,46SUH@74201|Verrucomicrobia,3K7K9@414999|Opitutae	414999|Opitutae	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
YHH3_k127_2436456_0	926569.ANT_11410	6.534e-201	641.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
YHH3_k127_2445060_2	583355.Caka_2455	1.306e-107	353.0	COG1249@1|root,COG1249@2|Bacteria,46S7E@74201|Verrucomicrobia,3K76N@414999|Opitutae	414999|Opitutae	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH3_k127_2445060_1	583355.Caka_1428	2.923e-109	364.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,46T3E@74201|Verrucomicrobia,3K8A3@414999|Opitutae	414999|Opitutae	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1
YHH3_k127_2445060_0	1121930.AQXG01000001_gene1141	6.789e-164	529.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1IPKZ@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH3_k127_2445060_5	278957.ABEA03000126_gene3711	3.943e-43	170.0	COG1609@1|root,COG1609@2|Bacteria,46Y9I@74201|Verrucomicrobia,3K968@414999|Opitutae	414999|Opitutae	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI
YHH3_k127_2445060_3	1265503.KB905160_gene2872	1.561e-81	289.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
YHH3_k127_2445060_4	1463920.JOGB01000043_gene1660	6.591e-70	259.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
YHH3_k127_2451061_0	301.JNHE01000012_gene1432	2.002e-166	532.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1YDWZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b2323,iAPECO1_1312.APECO1_4241,iB21_1397.B21_02208,iBWG_1329.BWG_2097,iE2348C_1286.E2348C_2463,iEC042_1314.EC042_2564,iEC55989_1330.EC55989_2567,iECABU_c1320.ECABU_c26560,iECBD_1354.ECBD_1336,iECB_1328.ECB_02248,iECDH10B_1368.ECDH10B_2485,iECDH1ME8569_1439.ECDH1ME8569_2261,iECD_1391.ECD_02248,iECED1_1282.ECED1_2787,iECIAI1_1343.ECIAI1_2400,iECIAI39_1322.ECIAI39_2472,iECNA114_1301.ECNA114_2414,iECO103_1326.ECO103_2787,iECO111_1330.ECO111_3071,iECO26_1355.ECO26_3311,iECOK1_1307.ECOK1_2605,iECP_1309.ECP_2362,iECS88_1305.ECS88_2471,iECSE_1348.ECSE_2632,iECSF_1327.ECSF_2200,iECUMN_1333.ECUMN_2663,iECW_1372.ECW_m2512,iEKO11_1354.EKO11_1442,iETEC_1333.ETEC_2459,iEcDH1_1363.EcDH1_1333,iEcHS_1320.EcHS_A2474,iEcSMS35_1347.EcSMS35_2480,iEcolC_1368.EcolC_1329,iJN746.PP_4175,iJO1366.b2323,iJR904.b2323,iLF82_1304.LF82_0605,iNRG857_1313.NRG857_11765,iSBO_1134.SBO_2360,iUMN146_1321.UM146_05195,iUTI89_1310.UTI89_C2608,iWFL_1372.ECW_m2512,iY75_1357.Y75_RS12180,ic_1306.c2869	Ketoacyl-synt_C,ketoacyl-synt
YHH3_k127_2451061_1	1298865.H978DRAFT_1480	2.011e-77	262.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,4657R@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b0954,iB21_1397.B21_00965,iBWG_1329.BWG_0806,iE2348C_1286.E2348C_0940,iEC042_1314.EC042_1039,iECBD_1354.ECBD_2641,iECB_1328.ECB_00958,iECDH10B_1368.ECDH10B_1024,iECD_1391.ECD_00958,iECED1_1282.ECED1_0977,iECH74115_1262.ECH74115_1118,iECIAI1_1343.ECIAI1_0995,iECIAI39_1322.ECIAI39_2193,iECNA114_1301.ECNA114_1032,iECO103_1326.ECO103_1000,iECO111_1330.ECO111_1022,iECO26_1355.ECO26_1081,iECOK1_1307.ECOK1_1013,iECS88_1305.ECS88_0975,iECSF_1327.ECSF_0868,iECSP_1301.ECSP_1060,iECUMN_1333.ECUMN_1143,iECW_1372.ECW_m1064,iECs_1301.ECs1038,iEKO11_1354.EKO11_2876,iETEC_1333.ETEC_1024,iEcE24377_1341.EcE24377A_1068,iEcHS_1320.EcHS_A1063,iEcSMS35_1347.EcSMS35_2166,iEcolC_1368.EcolC_2642,iG2583_1286.G2583_1189,iJO1366.b0954,iJR904.b0954,iLF82_1304.LF82_0604,iSBO_1134.SBO_2277,iSDY_1059.SDY_0927,iSF_1195.SF0954,iSSON_1240.SSON_0958,iSbBS512_1146.SbBS512_E2362,iUMNK88_1353.UMNK88_1108,iWFL_1372.ECW_m1064,iY75_1357.Y75_RS04955,iZ_1308.Z1304,ic_1306.c1090	FabA
YHH3_k127_2508652_0	483216.BACEGG_03289	3.655e-212	678.0	COG2730@1|root,COG2730@2|Bacteria,4NKKV@976|Bacteroidetes,2FRUH@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 115	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_115
YHH3_k127_2509618_7	71139.XP_010069499.1	0.0002263	49.0	28KFZ@1|root,2RDGW@2759|Eukaryota,37NG2@33090|Viridiplantae,3GFJG@35493|Streptophyta	35493|Streptophyta	S	At4g15970-like	-	-	-	-	-	-	-	-	-	-	-	-	Nucleotid_trans
YHH3_k127_2509618_4	240016.ABIZ01000001_gene310	6.763e-09	66.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
YHH3_k127_2509618_3	1177154.Y5S_02034	2.086e-22	106.0	COG0457@1|root,COG0457@2|Bacteria,1R2SZ@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
YHH3_k127_2509618_1	497964.CfE428DRAFT_5282	1.597e-145	471.0	COG0562@1|root,COG0562@2|Bacteria,46SKA@74201|Verrucomicrobia	74201|Verrucomicrobia	M	UDP-galactopyranose mutase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
YHH3_k127_2509618_0	452637.Oter_4009	3.243e-156	502.0	COG0156@1|root,COG0156@2|Bacteria,46TFY@74201|Verrucomicrobia,3K7SB@414999|Opitutae	414999|Opitutae	H	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH3_k127_2509618_2	794903.OPIT5_15210	4.213e-74	265.0	COG0438@1|root,COG0438@2|Bacteria,46V09@74201|Verrucomicrobia,3K7MD@414999|Opitutae	414999|Opitutae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YHH3_k127_2509618_6	452637.Oter_3820	0.0001618	50.0	2AXAP@1|root,31P9S@2|Bacteria,46XVW@74201|Verrucomicrobia,3K8EZ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2517764_0	382464.ABSI01000013_gene1571	0.0	1564.0	COG1572@1|root,COG3210@1|root,COG3386@1|root,COG4257@1|root,COG5373@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG4257@2|Bacteria,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	-	-	-	ko:K13277,ko:K15125,ko:K15539	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000,ko01002,ko03110	-	-	-	DUF5011
YHH3_k127_2525084_4	143224.JQMD01000002_gene1581	8.541e-27	113.0	COG5434@1|root,COG5434@2|Bacteria,4NG4T@976|Bacteroidetes,1IIH4@117743|Flavobacteriia	976|Bacteroidetes	G	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
YHH3_k127_2525084_3	1121011.AUCB01000046_gene686	3.686e-117	394.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia,23I7A@178469|Arenibacter	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_2525084_1	313628.LNTAR_22894	2.563e-290	907.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
YHH3_k127_2525084_0	1123070.KB899267_gene2471	1.869e-299	936.0	COG3345@1|root,COG3345@2|Bacteria,46XPU@74201|Verrucomicrobia,2IWC9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase
YHH3_k127_2525084_2	313628.LNTAR_22709	1.247e-119	392.0	COG2755@1|root,COG3119@1|root,COG2755@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Lipase_GDSL_2,Sulfatase
YHH3_k127_2528268_0	1123508.JH636439_gene346	3.959e-56	227.0	COG2706@1|root,COG3210@1|root,COG3391@1|root,COG4932@1|root,COG2706@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2IY8U@203682|Planctomycetes	203682|Planctomycetes	M	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH3_k127_2534572_1	1396418.BATQ01000183_gene968	3.967e-63	222.0	COG0386@1|root,COG0386@2|Bacteria,46V2M@74201|Verrucomicrobia,2IUDT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	GSHPx
YHH3_k127_2534572_0	1279015.KB908454_gene967	2.222e-135	441.0	COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1Y3FQ@135624|Aeromonadales	135624|Aeromonadales	C	Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate	astD	-	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
YHH3_k127_2562810_1	384765.SIAM614_17489	4.276e-235	739.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
YHH3_k127_2562810_2	794903.OPIT5_25355	2.613e-156	502.0	COG0343@1|root,COG0343@2|Bacteria,46TZR@74201|Verrucomicrobia,3K78J@414999|Opitutae	414999|Opitutae	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
YHH3_k127_2562810_0	1191523.MROS_0432	1.554e-266	854.0	COG0653@1|root,COG0653@2|Bacteria	2|Bacteria	U	protein targeting	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH3_k127_2562810_3	583355.Caka_2020	1.77e-120	406.0	COG0815@1|root,COG0815@2|Bacteria,46SPW@74201|Verrucomicrobia,3K74H@414999|Opitutae	414999|Opitutae	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
YHH3_k127_2562810_4	794903.OPIT5_22670	3.824e-65	240.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia,3K7AE@414999|Opitutae	414999|Opitutae	M	C-terminal domain of tail specific protease (DUF3340)	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
YHH3_k127_257917_6	1186051.BGIGA_301	0.0006651	43.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1HXSG@117743|Flavobacteriia,3IV7V@39782|Blattabacteriaceae	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YHH3_k127_257917_2	240016.ABIZ01000001_gene4088	9.153e-39	151.0	COG0558@1|root,COG0558@2|Bacteria,46T66@74201|Verrucomicrobia,2IUP6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
YHH3_k127_257917_7	1268240.ATFI01000001_gene3445	0.0007058	43.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,2FM7K@200643|Bacteroidia,4AP20@815|Bacteroidaceae	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_257917_5	583355.Caka_2866	5.092e-27	111.0	COG1141@1|root,COG1141@2|Bacteria,46WJZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
YHH3_k127_257917_0	583355.Caka_2865	1.783e-213	668.0	COG0826@1|root,COG0826@2|Bacteria,46UGV@74201|Verrucomicrobia,3K7QP@414999|Opitutae	2|Bacteria	O	Peptidase U32	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
YHH3_k127_257917_1	349741.Amuc_0030	3.631e-103	349.0	COG2334@1|root,COG2334@2|Bacteria,46TIS@74201|Verrucomicrobia,2IVEV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
YHH3_k127_257917_3	754477.Q7C_2088	1.769e-34	140.0	COG3647@1|root,COG3647@2|Bacteria,1RGJN@1224|Proteobacteria	1224|Proteobacteria	S	Membrane	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
YHH3_k127_257917_4	1123054.KB907723_gene2856	3.327e-30	134.0	COG3064@1|root,COG3064@2|Bacteria,1MXPS@1224|Proteobacteria,1RQIV@1236|Gammaproteobacteria,1X0HY@135613|Chromatiales	135613|Chromatiales	M	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
YHH3_k127_2622753_0	28229.ND2E_2839	1.081e-173	570.0	COG0265@1|root,COG0265@2|Bacteria,1MWCG@1224|Proteobacteria	1224|Proteobacteria	O	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
YHH3_k127_2649489_1	425104.Ssed_2795	7.547e-58	206.0	COG3153@1|root,COG3153@2|Bacteria,1RHPP@1224|Proteobacteria,1S7G1@1236|Gammaproteobacteria,2QC12@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM GCN5-related N-acetyltransferase	VVA1529	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,Acetyltransf_9
YHH3_k127_2649489_2	1237149.C900_05252	2.299e-55	200.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,47P77@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
YHH3_k127_2649489_0	1123277.KB893172_gene429	4.529e-80	275.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_2649489_3	485917.Phep_1597	2.022e-13	72.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,1IR5Y@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH3_k127_2665471_1	243090.RB605	1.571e-158	527.0	COG3119@1|root,COG3119@2|Bacteria,2J1ZQ@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_2665471_2	452637.Oter_0026	7.346e-95	340.0	COG1957@1|root,COG1957@2|Bacteria,46UGB@74201|Verrucomicrobia,3K9ZR@414999|Opitutae	414999|Opitutae	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
YHH3_k127_2665471_0	756272.Plabr_1613	3.197e-196	622.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_2665471_3	1304874.JAFY01000007_gene2070	3.694e-14	74.0	COG0194@1|root,COG0194@2|Bacteria	2|Bacteria	F	guanylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_kin
YHH3_k127_2667657_0	1408473.JHXO01000004_gene207	5.864e-122	400.0	COG1453@1|root,COG1453@2|Bacteria,4NGCW@976|Bacteroidetes,2FPG8@200643|Bacteroidia	976|Bacteroidetes	S	Tat pathway signal sequence domain protein	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
YHH3_k127_2667657_2	583355.Caka_1886	2.03e-90	304.0	COG1691@1|root,COG1691@2|Bacteria,46SQC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
YHH3_k127_2667657_1	583355.Caka_1887	2.103e-120	401.0	COG1641@1|root,COG1641@2|Bacteria,46THK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
YHH3_k127_2667657_3	583355.Caka_1888	1.872e-89	300.0	COG2836@1|root,COG2836@2|Bacteria,46YGR@74201|Verrucomicrobia,3K9JC@414999|Opitutae	414999|Opitutae	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
YHH3_k127_2667657_4	583355.Caka_1889	2.68e-52	188.0	COG1606@1|root,COG1606@2|Bacteria	2|Bacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
YHH3_k127_2673294_2	1129794.C427_3920	1.094e-23	111.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_35,CBM_6,CHRD,Calx-beta,DUF4347,DUF4397,He_PIG
YHH3_k127_2673294_1	941824.TCEL_00097	4.697e-39	153.0	COG1670@1|root,COG1670@2|Bacteria,1UI20@1239|Firmicutes,24HRV@186801|Clostridia,36JDG@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_4
YHH3_k127_2673294_0	595460.RRSWK_03380	8.796e-171	542.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,TAT_signal
YHH3_k127_2673294_3	1121924.ATWH01000005_gene2605	5.409e-10	71.0	COG1874@1|root,COG1874@2|Bacteria,2H2YV@201174|Actinobacteria,4FQYV@85023|Microbacteriaceae	201174|Actinobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2675361_2	530564.Psta_2573	8.055e-10	66.0	2AZY1@1|root,31S7T@2|Bacteria,2IZYE@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2675361_0	382464.ABSI01000003_gene4212	1.772e-174	554.0	COG2017@1|root,COG2017@2|Bacteria,46VDK@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
YHH3_k127_2675361_3	1288963.ADIS_1234	9.819e-07	52.0	COG3119@1|root,COG3408@1|root,COG3119@2|Bacteria,COG3408@2|Bacteria,4NHH7@976|Bacteroidetes,47NG8@768503|Cytophagia	976|Bacteroidetes	GP	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,DUF4976,Sulfatase
YHH3_k127_2675361_1	595460.RRSWK_05242	2.382e-109	358.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_268919_1	583355.Caka_2575	3.127e-110	364.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,3K7UD@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH3_k127_268919_0	382464.ABSI01000016_gene647	1.443e-126	415.0	COG1034@1|root,COG1034@2|Bacteria,46S6S@74201|Verrucomicrobia,2ITJ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
YHH3_k127_2697036_1	583355.Caka_2413	8.348e-195	612.0	COG0137@1|root,COG0137@2|Bacteria,46SCU@74201|Verrucomicrobia,3K7AT@414999|Opitutae	414999|Opitutae	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
YHH3_k127_2697036_0	583355.Caka_1478	0.0	1572.0	COG0209@1|root,COG0209@2|Bacteria,46SFJ@74201|Verrucomicrobia,3K76K@414999|Opitutae	414999|Opitutae	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
YHH3_k127_2697036_2	1123070.KB899253_gene1009	1.058e-164	526.0	COG0208@1|root,COG0208@2|Bacteria,46SMW@74201|Verrucomicrobia,2ITZI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Ribonucleotide reductase, small chain	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_red_sm
YHH3_k127_2697036_3	439235.Dalk_2237	1.237e-10	66.0	COG0477@1|root,COG2814@2|Bacteria,1R518@1224|Proteobacteria,43B4F@68525|delta/epsilon subdivisions,2WIQ4@28221|Deltaproteobacteria,2MIEM@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH3_k127_2705523_0	583355.Caka_2488	9.313e-85	284.0	COG0264@1|root,COG0264@2|Bacteria,46SUK@74201|Verrucomicrobia,3K76T@414999|Opitutae	414999|Opitutae	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
YHH3_k127_2705523_3	794903.OPIT5_11140	1.46e-47	177.0	COG1266@1|root,COG1266@2|Bacteria,46XTZ@74201|Verrucomicrobia,3K831@414999|Opitutae	414999|Opitutae	S	Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
YHH3_k127_2705523_1	583355.Caka_2037	5.521e-80	278.0	COG0142@1|root,COG0142@2|Bacteria,46SKW@74201|Verrucomicrobia,3K74B@414999|Opitutae	414999|Opitutae	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH3_k127_2705523_2	382464.ABSI01000013_gene1783	1.328e-75	260.0	COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_2705523_4	583355.Caka_1847	0.0006033	49.0	2AXA3@1|root,31P96@2|Bacteria,46XVB@74201|Verrucomicrobia,3K8DE@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2740308_0	583355.Caka_1872	8.006e-149	485.0	COG1418@1|root,COG1418@2|Bacteria,46U1S@74201|Verrucomicrobia,3K7E0@414999|Opitutae	414999|Opitutae	A	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
YHH3_k127_2740308_3	240016.ABIZ01000001_gene5647	2.423e-13	76.0	COG0848@1|root,COG0848@2|Bacteria,46WPD@74201|Verrucomicrobia,2IUY5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
YHH3_k127_2740308_2	382464.ABSI01000006_gene777	6.875e-15	79.0	COG0848@1|root,COG0848@2|Bacteria,46W26@74201|Verrucomicrobia,2IUYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
YHH3_k127_2740308_1	452637.Oter_3186	2.815e-24	103.0	COG2197@1|root,COG2197@2|Bacteria,46T2B@74201|Verrucomicrobia,3K7X9@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_2762442_0	926550.CLDAP_14400	4.778e-265	833.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2G65R@200795|Chloroflexi	200795|Chloroflexi	C	malic protein domain protein	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,malic
YHH3_k127_2766993_2	583355.Caka_2486	4.458e-09	61.0	COG0071@1|root,COG0071@2|Bacteria,46WRX@74201|Verrucomicrobia,3K89J@414999|Opitutae	414999|Opitutae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
YHH3_k127_2766993_1	1167006.UWK_01212	2.185e-13	76.0	COG0071@1|root,COG0071@2|Bacteria,1N4NW@1224|Proteobacteria,42UNZ@68525|delta/epsilon subdivisions,2WR41@28221|Deltaproteobacteria,2MKGX@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YHH3_k127_2766993_0	382464.ABSI01000005_gene1136	2.877e-54	199.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,46TTA@74201|Verrucomicrobia,2IU1V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
YHH3_k127_2772423_0	649639.Bcell_2329	0.0	1053.0	COG3459@1|root,COG3459@2|Bacteria,1TVMK@1239|Firmicutes,4H9ZP@91061|Bacilli,1ZF4F@1386|Bacillus	91061|Bacilli	G	Glycosyl hydrolase 36 superfamily, catalytic domain	chvB1	-	2.4.1.20,2.4.1.333	ko:K00702,ko:K13688,ko:K21298	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36
YHH3_k127_2772423_1	756272.Plabr_3144	1.767e-61	225.0	COG1609@1|root,COG2207@1|root,COG1609@2|Bacteria,COG2207@2|Bacteria,2J29A@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Peripla_BP_3
YHH3_k127_2809380_0	595460.RRSWK_02095	9.863e-248	773.0	COG4146@1|root,COG4146@2|Bacteria,2J29I@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_2809380_1	595460.RRSWK_01711	4.188e-116	389.0	COG3119@1|root,COG3119@2|Bacteria,2IXHT@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_2809380_3	595460.RRSWK_02390	2.28e-111	377.0	COG3119@1|root,COG3119@2|Bacteria,2J1TA@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_2809380_2	756272.Plabr_3163	2.326e-112	372.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
YHH3_k127_2809380_4	497964.CfE428DRAFT_4144	5.927e-34	144.0	2CK9T@1|root,2Z7W9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2826176_0	583355.Caka_0983	0.0	1161.0	COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
YHH3_k127_2826176_1	662479.C440_06797	3.364e-05	46.0	COG0123@1|root,arCOG00324@2157|Archaea,2XT0B@28890|Euryarchaeota,23S80@183963|Halobacteria	183963|Halobacteria	BQ	COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein	hda1	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
YHH3_k127_282992_0	313628.LNTAR_22714	3.366e-74	256.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_282992_1	1396418.BATQ01000177_gene2881	2.94e-06	59.0	COG1404@1|root,COG4932@1|root,COG5267@1|root,COG1404@2|Bacteria,COG4932@2|Bacteria,COG5267@2|Bacteria,46XBA@74201|Verrucomicrobia,2IV9X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	H-type lectin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
YHH3_k127_2833924_7	382464.ABSI01000021_gene425	3.014e-22	99.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia,2ITRR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Uroporphyrinogen-III synthase HemD	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
YHH3_k127_2833924_4	382464.ABSI01000021_gene424	1.384e-76	266.0	COG0181@1|root,COG0181@2|Bacteria,46SWD@74201|Verrucomicrobia,2IU65@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Porphobilinogen deaminase, dipyromethane cofactor binding domain	-	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
YHH3_k127_2833924_0	583355.Caka_1137	9.109e-164	520.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	414999|Opitutae	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
YHH3_k127_2833924_6	583355.Caka_1136	1.703e-58	208.0	COG0440@1|root,COG0440@2|Bacteria,46SUP@74201|Verrucomicrobia,3K810@414999|Opitutae	414999|Opitutae	E	acetolactate synthase	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
YHH3_k127_2833924_3	382464.ABSI01000011_gene3119	1.638e-101	335.0	COG0689@1|root,COG0689@2|Bacteria,46U55@74201|Verrucomicrobia,2ITNM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
YHH3_k127_2833924_5	631362.Thi970DRAFT_02626	4.549e-66	250.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WVYT@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
YHH3_k127_2833924_1	1089548.KI783301_gene638	5.694e-137	447.0	COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,3WFFB@539002|Bacillales incertae sedis	91061|Bacilli	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
YHH3_k127_2833924_2	404380.Gbem_1465	1.472e-116	382.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,43TQR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
YHH3_k127_2856589_1	244581.IM40_02165	9.253e-11	65.0	COG3177@1|root,COG3177@2|Bacteria,1MWAU@1224|Proteobacteria,2V6AK@28211|Alphaproteobacteria,47F4Y@766|Rickettsiales	766|Rickettsiales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH3_k127_2856589_0	404589.Anae109_3529	2.21e-18	99.0	2CA5X@1|root,33BSQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2862006_2	234267.Acid_6615	1.347e-07	64.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2862006_1	1408473.JHXO01000007_gene811	3.747e-25	121.0	295NE@1|root,2ZSZT@2|Bacteria,4NPQK@976|Bacteroidetes,2FSXA@200643|Bacteroidia	976|Bacteroidetes	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
YHH3_k127_2862006_0	313628.LNTAR_05679	1.287e-213	678.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_2874722_0	382464.ABSI01000013_gene1830	7.274e-65	242.0	COG1629@1|root,COG1629@2|Bacteria	382464.ABSI01000013_gene1830|-	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2874722_1	1007103.AFHW01000114_gene3782	4.397e-10	73.0	COG3291@1|root,COG5297@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5297@2|Bacteria,COG5492@2|Bacteria,1VHZ6@1239|Firmicutes,4IUF7@91061|Bacilli,26Y2R@186822|Paenibacillaceae	91061|Bacilli	G	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,fn3
YHH3_k127_287613_8	880070.Cycma_3118	1.242e-23	108.0	COG1409@1|root,COG1409@2|Bacteria,4NKP0@976|Bacteroidetes,47XAK@768503|Cytophagia	976|Bacteroidetes	S	Pfam:DUF303	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Metallophos,SASA
YHH3_k127_287613_10	1121904.ARBP01000001_gene5999	1.333e-21	102.0	2C4KB@1|root,32YM4@2|Bacteria,4NUZU@976|Bacteroidetes,47RBT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_287613_2	1121859.KB890756_gene1562	5.198e-60	211.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,47QN0@768503|Cytophagia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
YHH3_k127_287613_11	1408473.JHXO01000001_gene1989	3.964e-20	93.0	COG1320@1|root,COG1320@2|Bacteria,4NR0V@976|Bacteroidetes,2FZ6C@200643|Bacteroidia	976|Bacteroidetes	P	Na+/H+ antiporter subunit	mrpG	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
YHH3_k127_287613_12	1158182.KB905020_gene2227	2.817e-15	80.0	COG2212@1|root,COG2212@2|Bacteria,1N7BC@1224|Proteobacteria,1SE0C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Multiple resistance and pH regulation protein F	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
YHH3_k127_287613_9	237368.SCABRO_02535	1.099e-22	101.0	COG1863@1|root,COG1863@2|Bacteria,2J0NP@203682|Planctomycetes	203682|Planctomycetes	P	Na+/H+ ion antiporter subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
YHH3_k127_287613_1	583355.Caka_1383	2.187e-171	552.0	COG0651@1|root,COG0651@2|Bacteria,46ZH8@74201|Verrucomicrobia,3K7SI@414999|Opitutae	414999|Opitutae	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
YHH3_k127_287613_3	583355.Caka_1384	9.536e-38	145.0	COG1006@1|root,COG1006@2|Bacteria,46XWJ@74201|Verrucomicrobia,3K8GW@414999|Opitutae	414999|Opitutae	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
YHH3_k127_287613_5	583355.Caka_1385	5.252e-35	142.0	COG2111@1|root,COG2111@2|Bacteria,46XV3@74201|Verrucomicrobia,3K8CE@414999|Opitutae	414999|Opitutae	P	Domain related to MnhB subunit of Na+/H+ antiporter	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
YHH3_k127_287613_0	583355.Caka_1386	8.527e-200	647.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,46SDU@74201|Verrucomicrobia,3K79G@414999|Opitutae	414999|Opitutae	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	-	ko:K05565,ko:K14086	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,Proton_antipo_M,Proton_antipo_N
YHH3_k127_287613_4	879212.DespoDRAFT_02171	2.609e-37	152.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YHH3_k127_287613_6	583355.Caka_1457	1.147e-32	130.0	COG1846@1|root,COG1846@2|Bacteria,46WJ3@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
YHH3_k127_287613_7	583355.Caka_1459	7.357e-26	109.0	COG2352@1|root,COG2352@2|Bacteria,46SIN@74201|Verrucomicrobia,3K7TR@414999|Opitutae	414999|Opitutae	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	-	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
YHH3_k127_2883862_4	452637.Oter_3916	9.271e-56	196.0	COG1196@1|root,COG1196@2|Bacteria,46TT8@74201|Verrucomicrobia,3K7E6@414999|Opitutae	414999|Opitutae	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YHH3_k127_2883862_3	382464.ABSI01000010_gene3418	2.848e-68	238.0	COG0225@1|root,COG0225@2|Bacteria,46SSF@74201|Verrucomicrobia,2IU9E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
YHH3_k127_2883862_5	338966.Ppro_0126	1.045e-31	130.0	COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,431QN@68525|delta/epsilon subdivisions,2WX4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
YHH3_k127_2883862_0	382464.ABSI01000005_gene1170	1.82e-175	563.0	COG1640@1|root,COG1640@2|Bacteria,46SX0@74201|Verrucomicrobia,2ITJ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	4-alpha-glucanotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_77
YHH3_k127_2883862_2	313628.LNTAR_10381	1.702e-82	283.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	dhaA	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.8.1.5	ko:K01563,ko:K22318	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
YHH3_k127_2883862_1	583355.Caka_1901	2.148e-86	293.0	COG0332@1|root,COG0332@2|Bacteria,46UBS@74201|Verrucomicrobia,3K7QN@414999|Opitutae	414999|Opitutae	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	-	ko:K22317	-	-	-	-	ko00000	-	-	-	ACP_syn_III,ACP_syn_III_C
YHH3_k127_2893148_0	439235.Dalk_2128	2.063e-82	302.0	COG5492@1|root,COG5492@2|Bacteria,1R8Z4@1224|Proteobacteria,42U3Q@68525|delta/epsilon subdivisions,2WQZX@28221|Deltaproteobacteria,2MKPP@213118|Desulfobacterales	28221|Deltaproteobacteria	N	PFAM Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566,Peptidase_C13
YHH3_k127_289617_2	583355.Caka_2233	8.355e-34	133.0	COG0414@1|root,COG0414@2|Bacteria,46SRN@74201|Verrucomicrobia,3K7TI@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
YHH3_k127_289617_0	439235.Dalk_4332	9.268e-178	571.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MIMB@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH3_k127_289617_1	1463821.JOGR01000010_gene3711	7.133e-44	178.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4EXZD@85014|Glycomycetales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YHH3_k127_2898878_0	926569.ANT_06500	7.361e-139	447.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH3_k127_2898878_1	926569.ANT_06520	3.477e-104	345.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH3_k127_2898878_2	926569.ANT_06530	3.79e-101	337.0	COG2604@1|root,COG2604@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,DUF2920,MAF_flag10
YHH3_k127_2898878_3	926569.ANT_06540	5.362e-81	278.0	COG1215@1|root,COG1215@2|Bacteria,2G8MG@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_2905371_1	1144275.COCOR_03695	5.916e-61	233.0	COG3055@1|root,COG3055@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2905371_3	1396141.BATP01000022_gene331	2.275e-27	129.0	COG5184@1|root,COG5184@2|Bacteria,46XQ3@74201|Verrucomicrobia,2IWCT@203494|Verrucomicrobiae	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,He_PIG,HemolysinCabind,RCC1_2
YHH3_k127_2905371_0	880070.Cycma_0165	2.157e-131	431.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH3_k127_2905371_2	1123242.JH636434_gene3779	2.104e-41	158.0	2CCP0@1|root,2Z7XN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH3_k127_2913043_0	382464.ABSI01000020_gene302	0.0	1207.0	COG0525@1|root,COG0525@2|Bacteria,46SGP@74201|Verrucomicrobia,2IU1F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
YHH3_k127_2913043_1	583355.Caka_1041	1.02e-72	255.0	COG2159@1|root,COG2159@2|Bacteria,46VK5@74201|Verrucomicrobia,3K854@414999|Opitutae	414999|Opitutae	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
YHH3_k127_2913043_3	517417.Cpar_0456	9.08e-64	223.0	COG0551@1|root,COG0551@2|Bacteria,1FF54@1090|Chlorobi	1090|Chlorobi	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2913043_2	583355.Caka_1858	1.076e-68	241.0	COG1212@1|root,COG1212@2|Bacteria,46SS4@74201|Verrucomicrobia,3K7GX@414999|Opitutae	414999|Opitutae	M	Cytidylyltransferase	-	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
YHH3_k127_2915828_2	686340.Metal_0970	5.642e-43	164.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1XE23@135618|Methylococcales	135618|Methylococcales	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH3_k127_2915828_0	686340.Metal_0971	2.789e-212	674.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1XH1A@135618|Methylococcales	135618|Methylococcales	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_2915828_1	941449.dsx2_2278	4.324e-77	269.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42R8A@68525|delta/epsilon subdivisions,2WM6Z@28221|Deltaproteobacteria,2MGB8@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
YHH3_k127_2926656_13	158500.BV97_02459	0.0002839	44.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH3_k127_2926656_2	1304885.AUEY01000006_gene745	9.236e-118	418.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA,MASE1,PAS_3,Response_reg
YHH3_k127_2926656_11	583355.Caka_1419	4.852e-29	119.0	COG0799@1|root,COG0799@2|Bacteria,46WCF@74201|Verrucomicrobia,3K89X@414999|Opitutae	414999|Opitutae	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
YHH3_k127_2926656_9	382464.ABSI01000011_gene2745	3.143e-39	154.0	COG1057@1|root,COG1057@2|Bacteria,46YSF@74201|Verrucomicrobia,2IUSZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YHH3_k127_2926656_8	583355.Caka_1421	1.249e-46	179.0	COG3932@1|root,COG3932@2|Bacteria,46ZI1@74201|Verrucomicrobia,3K86N@414999|Opitutae	414999|Opitutae	S	Exopolysaccharide synthesis, ExoD	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
YHH3_k127_2926656_0	583355.Caka_1618	6.672e-214	691.0	COG1523@1|root,COG1523@2|Bacteria,46UHI@74201|Verrucomicrobia,3K7P7@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
YHH3_k127_2926656_4	349741.Amuc_0644	6.196e-108	361.0	COG0482@1|root,COG0482@2|Bacteria,46SQW@74201|Verrucomicrobia,2ITRY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
YHH3_k127_2926656_10	1396141.BATP01000035_gene4040	2.785e-31	129.0	COG0250@1|root,COG0250@2|Bacteria,46ZE1@74201|Verrucomicrobia,2IV04@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
YHH3_k127_2926656_6	794903.OPIT5_23520	3.236e-90	317.0	COG0265@1|root,COG0265@2|Bacteria,46YTI@74201|Verrucomicrobia,3K7TT@414999|Opitutae	414999|Opitutae	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2
YHH3_k127_2926656_7	670487.Ocepr_0960	2.411e-89	301.0	COG0428@1|root,COG0428@2|Bacteria,1WIUI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	divalent heavy-metal cations transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
YHH3_k127_2926656_1	1123070.KB899248_gene143	8.77e-149	483.0	COG0635@1|root,COG0635@2|Bacteria,46YUA@74201|Verrucomicrobia,2IVA8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
YHH3_k127_2926656_5	1379270.AUXF01000005_gene406	4.057e-99	340.0	COG1232@1|root,COG1232@2|Bacteria,1ZUZT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
YHH3_k127_2926656_3	382464.ABSI01000005_gene1324	2.782e-112	375.0	COG0635@1|root,COG0635@2|Bacteria,46STN@74201|Verrucomicrobia,2ITVN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YHH3_k127_2926656_12	382464.ABSI01000005_gene1323	1.3e-18	91.0	2F1X5@1|root,33UWR@2|Bacteria,46V3H@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2931254_4	1396141.BATP01000060_gene4729	3.22e-20	103.0	29ZR2@1|root,30MRV@2|Bacteria,46XMI@74201|Verrucomicrobia,2IW71@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2931254_1	452637.Oter_4591	4.472e-152	493.0	COG1624@1|root,COG1762@1|root,COG1624@2|Bacteria,COG1762@2|Bacteria,46TVS@74201|Verrucomicrobia,3K7HC@414999|Opitutae	414999|Opitutae	H	Diadenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N,PTS_EIIA_2
YHH3_k127_2931254_0	794903.OPIT5_12200	4.023e-190	604.0	COG0322@1|root,COG0322@2|Bacteria,46SAJ@74201|Verrucomicrobia,3K7BJ@414999|Opitutae	414999|Opitutae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
YHH3_k127_2931254_2	583355.Caka_2308	3.941e-110	372.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46USH@74201|Verrucomicrobia,3K738@414999|Opitutae	414999|Opitutae	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
YHH3_k127_2931254_3	436229.JOEH01000014_gene6064	1.07e-20	108.0	COG4409@1|root,COG4409@2|Bacteria,2GN94@201174|Actinobacteria,2NEQG@228398|Streptacidiphilus	201174|Actinobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
YHH3_k127_2942824_2	1121403.AUCV01000019_gene3274	3.93e-49	180.0	COG0477@1|root,COG2814@2|Bacteria,1R518@1224|Proteobacteria,43B4F@68525|delta/epsilon subdivisions,2WIQ4@28221|Deltaproteobacteria,2MIEM@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH3_k127_2942824_1	583355.Caka_2062	7.497e-121	399.0	COG0560@1|root,COG0560@2|Bacteria,46UCT@74201|Verrucomicrobia,3K7I3@414999|Opitutae	414999|Opitutae	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2942824_0	1173020.Cha6605_5693	1.218e-177	579.0	COG1770@1|root,COG1770@2|Bacteria	2|Bacteria	E	oligopeptidase activity	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
YHH3_k127_294687_0	583355.Caka_1448	7.852e-173	548.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH3_k127_294687_2	614083.AWQR01000022_gene41	2.786e-49	193.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,4AD4K@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH3_k127_294687_3	452637.Oter_0707	2.482e-31	129.0	2ET5N@1|root,33KPQ@2|Bacteria,46WTU@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_294687_1	382464.ABSI01000010_gene3466	7.525e-80	282.0	COG1506@1|root,COG1506@2|Bacteria,46TMD@74201|Verrucomicrobia	74201|Verrucomicrobia	E	peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
YHH3_k127_2961832_0	478741.JAFS01000001_gene1443	3.188e-228	722.0	COG0366@1|root,COG0366@2|Bacteria,46S7A@74201|Verrucomicrobia,37FYF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
YHH3_k127_2961832_4	1499967.BAYZ01000194_gene3126	4.981e-19	90.0	COG4627@1|root,COG4627@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
YHH3_k127_2961832_1	1403819.BATR01000002_gene80	1.08e-118	390.0	COG0176@1|root,COG0176@2|Bacteria,46UAK@74201|Verrucomicrobia,2ITMF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	TAL_FSA
YHH3_k127_2961832_3	443254.Marpi_1669	3.106e-24	103.0	COG0102@1|root,COG0102@2|Bacteria,2GD15@200918|Thermotogae	200918|Thermotogae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YHH3_k127_2983229_0	452637.Oter_1353	9.985e-211	675.0	COG0591@1|root,COG0591@2|Bacteria,46TXT@74201|Verrucomicrobia,3K9P0@414999|Opitutae	414999|Opitutae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_2983229_1	382464.ABSI01000007_gene4151	3.22e-120	396.0	COG1609@1|root,COG1609@2|Bacteria,46V1T@74201|Verrucomicrobia,2IVXE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI
YHH3_k127_2983229_4	290318.Cvib_0667	1.037e-08	59.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
YHH3_k127_2983229_2	1122214.AQWH01000017_gene4668	6.302e-30	121.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
YHH3_k127_2985039_3	382464.ABSI01000021_gene431	1.574e-42	158.0	COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,2ITGM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_2985039_0	583355.Caka_1896	1.082e-143	469.0	COG1160@1|root,COG1160@2|Bacteria,46SJY@74201|Verrucomicrobia,3K77B@414999|Opitutae	414999|Opitutae	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
YHH3_k127_2985039_2	583355.Caka_0251	2.588e-71	254.0	COG0223@1|root,COG0223@2|Bacteria,46SKS@74201|Verrucomicrobia,3K7UM@414999|Opitutae	414999|Opitutae	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YHH3_k127_2985039_4	583355.Caka_2466	1.354e-27	120.0	COG1388@1|root,COG1388@2|Bacteria,46WB7@74201|Verrucomicrobia,3K845@414999|Opitutae	414999|Opitutae	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
YHH3_k127_2985039_1	382464.ABSI01000021_gene435	9.329e-88	301.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia,2IU4T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YHH3_k127_2985039_5	452637.Oter_3743	7.086e-10	61.0	COG1314@1|root,COG1314@2|Bacteria,46T75@74201|Verrucomicrobia,3K89V@414999|Opitutae	414999|Opitutae	U	PFAM Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
YHH3_k127_2989433_4	583355.Caka_1236	2.642e-79	270.0	COG1974@1|root,COG1974@2|Bacteria,46SU8@74201|Verrucomicrobia,3K8BT@414999|Opitutae	414999|Opitutae	K	Represses a number of genes involved in the response to DNA damage (SOS response)	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
YHH3_k127_2989433_3	1396141.BATP01000004_gene5901	2.138e-79	284.0	COG1179@1|root,COG1179@2|Bacteria,46THP@74201|Verrucomicrobia,2IU4H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiF family	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
YHH3_k127_2989433_0	583355.Caka_0775	8.489e-204	642.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,3K7NF@414999|Opitutae	414999|Opitutae	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH3_k127_2989433_2	1304284.L21TH_1357	1.311e-116	384.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,36EZ7@31979|Clostridiaceae	186801|Clostridia	P	K -dependent Na Ca exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
YHH3_k127_2989433_1	583355.Caka_0908	4.81e-136	438.0	COG0696@1|root,COG0696@2|Bacteria,46U4C@74201|Verrucomicrobia,3K7DS@414999|Opitutae	414999|Opitutae	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
YHH3_k127_3004197_3	313628.LNTAR_01005	2.412e-30	130.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_3004197_2	267608.RSc0827	5.341e-41	165.0	COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,2VV6E@28216|Betaproteobacteria,1K72K@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
YHH3_k127_3004197_1	344747.PM8797T_19201	3.335e-41	161.0	28J3W@1|root,2Z900@2|Bacteria,2IZRG@203682|Planctomycetes	203682|Planctomycetes	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
YHH3_k127_3004197_4	10224.XP_002739253.1	2.95e-12	69.0	COG3119@1|root,KOG3867@2759|Eukaryota,38DUV@33154|Opisthokonta,3B9HA@33208|Metazoa,3CZ4K@33213|Bilateria	33208|Metazoa	P	cerebroside-sulfatase activity	ARSA	GO:0000003,GO:0000323,GO:0001669,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005768,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006914,GO:0006950,GO:0006952,GO:0006955,GO:0007275,GO:0007338,GO:0007339,GO:0007399,GO:0007417,GO:0007584,GO:0008037,GO:0008150,GO:0008152,GO:0008484,GO:0009056,GO:0009268,GO:0009566,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009897,GO:0009986,GO:0009987,GO:0009988,GO:0009991,GO:0010033,GO:0012505,GO:0016020,GO:0016021,GO:0016192,GO:0016787,GO:0016788,GO:0019897,GO:0019898,GO:0019953,GO:0022414,GO:0030141,GO:0031224,GO:0031232,GO:0031410,GO:0031667,GO:0031974,GO:0031982,GO:0031983,GO:0032501,GO:0032502,GO:0032940,GO:0034774,GO:0035036,GO:0035578,GO:0036230,GO:0042119,GO:0042221,GO:0042493,GO:0042582,GO:0042742,GO:0043167,GO:0043169,GO:0043202,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043627,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0045055,GO:0045321,GO:0045471,GO:0046677,GO:0046872,GO:0046903,GO:0048731,GO:0048856,GO:0050896,GO:0051179,GO:0051234,GO:0051597,GO:0051704,GO:0051707,GO:0060205,GO:0061919,GO:0070013,GO:0071704,GO:0071944,GO:0097223,GO:0097305,GO:0097708,GO:0098542,GO:0098552,GO:0099503,GO:1901135,GO:1901564,GO:1901700,GO:1903509	3.1.6.2,3.1.6.8	ko:K01131,ko:K01134,ko:K12381	ko00140,ko00600,ko04142,map00140,map00600,map04142	-	R03404,R04856,R08941,R08942	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
YHH3_k127_3004197_0	1123242.JH636435_gene1640	2.753e-58	211.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
YHH3_k127_3009228_0	1191523.MROS_2342	1.27e-11	73.0	COG3866@1|root,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	pel3	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pectinesterase
YHH3_k127_3055516_2	494419.ALPM01000004_gene1758	6.704e-06	49.0	COG2963@1|root,COG2963@2|Bacteria,2IPC7@201174|Actinobacteria,1WC82@1268|Micrococcaceae	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
YHH3_k127_3055516_0	583355.Caka_0688	1.359e-93	328.0	2F6YF@1|root,33PYZ@2|Bacteria,46TE0@74201|Verrucomicrobia,3K7ET@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3055516_1	583355.Caka_1722	9.596e-38	145.0	COG1694@1|root,COG1694@2|Bacteria,46W6C@74201|Verrucomicrobia,3K875@414999|Opitutae	414999|Opitutae	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
YHH3_k127_3077911_1	616991.JPOO01000003_gene1738	5.226e-10	60.0	COG2730@1|root,COG2730@2|Bacteria,4NF3J@976|Bacteroidetes,1I1P4@117743|Flavobacteriia	976|Bacteroidetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
YHH3_k127_3077911_0	240016.ABIZ01000001_gene5493	2.414e-15	80.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YHH3_k127_3078697_1	1042376.AFPK01000062_gene1307	2.03e-84	288.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes	976|Bacteroidetes	P	Arylsulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
YHH3_k127_3078697_0	756272.Plabr_1070	1.783e-190	608.0	COG0657@1|root,COG3119@1|root,COG0657@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,Pectinesterase
YHH3_k127_3091418_0	382464.ABSI01000011_gene2385	6.26e-224	706.0	COG0659@1|root,COG0659@2|Bacteria,46UA5@74201|Verrucomicrobia,2IWMC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
YHH3_k127_3091418_2	1123400.KB904767_gene3421	7.305e-60	208.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
YHH3_k127_3091418_1	583355.Caka_0705	8.926e-158	510.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_3111676_1	497965.Cyan7822_0536	2.028e-23	101.0	COG2755@1|root,COG2755@2|Bacteria,1G70I@1117|Cyanobacteria	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH3_k127_3111676_0	278957.ABEA03000196_gene407	2.01e-140	454.0	COG0407@1|root,COG0407@2|Bacteria,46WW7@74201|Verrucomicrobia,3K8TQ@414999|Opitutae	414999|Opitutae	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH3_k127_3111676_2	1382359.JIAL01000001_gene78	1.409e-17	91.0	COG1917@1|root,COG2169@1|root,COG1917@2|Bacteria,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	3.2.2.21	ko:K02099,ko:K13529,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,AraC_binding,Cupin_2,Endonuclea_NS_2,HTH_18,HTH_AraC
YHH3_k127_3115515_1	234267.Acid_2264	1.79e-138	452.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
YHH3_k127_3115515_0	583355.Caka_1826	1.958e-160	516.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4,Porin_O_P
YHH3_k127_3115515_4	583355.Caka_1827	1.618e-55	199.0	COG4659@1|root,COG4659@2|Bacteria,46VAU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
YHH3_k127_3115515_3	583355.Caka_1828	6.216e-62	221.0	COG3182@1|root,COG3182@2|Bacteria	2|Bacteria	E	Iron-regulated membrane protein	ynaJ	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
YHH3_k127_3115515_2	641524.ADICYQ_3336	4.336e-104	354.0	COG1409@1|root,COG1409@2|Bacteria,4NEYU@976|Bacteroidetes,47KM8@768503|Cytophagia	976|Bacteroidetes	S	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
YHH3_k127_3115515_5	1121405.dsmv_1970	4.561e-18	87.0	COG2329@1|root,COG2329@2|Bacteria,1NBCH@1224|Proteobacteria,42VX2@68525|delta/epsilon subdivisions,2WRPB@28221|Deltaproteobacteria,2MM0B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
YHH3_k127_3123499_1	595460.RRSWK_04293	5.374e-251	783.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_3123499_2	595460.RRSWK_04264	3.549e-229	715.0	COG3119@1|root,COG3119@2|Bacteria,2IX69@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_3123499_0	595460.RRSWK_04265	3.733e-258	802.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_313015_3	1336237.JAEE01000004_gene2162	8.892e-08	64.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	type VI secretion protein	impC	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
YHH3_k127_313015_1	1198114.AciX9_0268	2.613e-40	154.0	COG4104@1|root,COG4104@2|Bacteria,3Y5VI@57723|Acidobacteria,2JNSN@204432|Acidobacteriia	204432|Acidobacteriia	S	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
YHH3_k127_313015_0	497964.CfE428DRAFT_2851	3.988e-111	383.0	2F7XU@1|root,340BQ@2|Bacteria,46VS8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3154580_1	762903.Pedsa_0718	7.101e-103	373.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	plyA1	-	4.2.2.8	ko:K12547,ko:K19052	-	-	-	-	ko00000,ko01000	-	PL12	-	Beta_helix,Glyco_hydro_28,Pectate_lyase_3
YHH3_k127_3154580_0	762984.HMPREF9445_01902	3.209e-167	567.0	COG2730@1|root,COG2730@2|Bacteria,4NKKV@976|Bacteroidetes,2FRUH@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 115	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_115
YHH3_k127_3154646_0	143224.JQMD01000002_gene180	2.89e-280	877.0	COG3525@1|root,COG3525@2|Bacteria,4NH5U@976|Bacteroidetes,1IBP1@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase, family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20b
YHH3_k127_3172235_4	862908.BMS_0894	5.409e-19	94.0	COG2353@1|root,COG2353@2|Bacteria,1R1V2@1224|Proteobacteria,43DBA@68525|delta/epsilon subdivisions,2X8H9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
YHH3_k127_3172235_0	243090.RB5195	2.923e-154	500.0	COG3119@1|root,COG3119@2|Bacteria,2J1QG@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_3172235_3	1298593.TOL_2194	6.47e-27	123.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_14,Glyco_hydro_42
YHH3_k127_3172235_1	1173028.ANKO01000044_gene722	1.781e-108	361.0	COG3540@1|root,COG3540@2|Bacteria,1GAVZ@1117|Cyanobacteria	1117|Cyanobacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
YHH3_k127_3172235_2	641524.ADICYQ_1401	4.675e-94	325.0	COG3119@1|root,COG3119@2|Bacteria,4NP9D@976|Bacteroidetes	976|Bacteroidetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_3200893_0	760192.Halhy_5306	8.788e-156	505.0	COG1435@1|root,COG1435@2|Bacteria,4NFWU@976|Bacteroidetes,1INV3@117747|Sphingobacteriia	976|Bacteroidetes	F	PFAM RagB SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
YHH3_k127_3200893_1	1166018.FAES_5035	1.005e-133	436.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47KT8@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
YHH3_k127_3203279_2	1499967.BAYZ01000164_gene6661	4.099e-153	520.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,2NS5N@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,dCache_1
YHH3_k127_3203279_8	1499967.BAYZ01000088_gene5143	7.424e-66	239.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,PAS_9,Pkinase,Response_reg
YHH3_k127_3203279_9	1173263.Syn7502_01411	1.235e-64	241.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	ETR2	-	1.8.1.9,3.1.3.3	ko:K00384,ko:K07315	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03021	-	-	-	HATPase_c,HisKA,PAS,Response_reg
YHH3_k127_3203279_1	452637.Oter_1863	8.703e-180	569.0	COG0563@1|root,COG0563@2|Bacteria,46SW4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
YHH3_k127_3203279_4	693661.Arcve_0466	1.383e-137	459.0	arCOG05009@1|root,arCOG05009@2157|Archaea,2XZTV@28890|Euryarchaeota,246TV@183980|Archaeoglobi	183980|Archaeoglobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3203279_3	697281.Mahau_0168	1.359e-144	471.0	COG0673@1|root,COG0673@2|Bacteria,1V0JH@1239|Firmicutes,249FB@186801|Clostridia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_3203279_5	886293.Sinac_7534	1.879e-110	368.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3203279_7	472759.Nhal_1652	6.743e-82	289.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1S1F9@1236|Gammaproteobacteria,1X1BJ@135613|Chromatiales	135613|Chromatiales	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
YHH3_k127_3203279_6	247490.KSU1_C0638	2.402e-82	289.0	COG0845@1|root,COG0845@2|Bacteria,2J0F5@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YHH3_k127_3203279_0	880073.Calab_1257	2.149e-311	984.0	COG3696@1|root,COG3696@2|Bacteria,2NNKZ@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
YHH3_k127_3236666_2	1122605.KB893625_gene2189	4.451e-11	64.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes	976|Bacteroidetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_3236666_1	575540.Isop_0606	1.255e-17	96.0	COG1413@1|root,COG1413@2|Bacteria,2J0ZX@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_3236666_0	344747.PM8797T_17127	1.326e-56	216.0	COG1413@1|root,COG1413@2|Bacteria,2IYWU@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_3243_0	595460.RRSWK_04423	3.998e-288	896.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
YHH3_k127_3243_4	1123070.KB899262_gene1686	3.218e-79	271.0	COG2197@1|root,COG2197@2|Bacteria,46XIF@74201|Verrucomicrobia,2IW0D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_3243_1	595460.RRSWK_04252	6.427e-209	668.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
YHH3_k127_3243_2	143224.JQMD01000002_gene209	3.937e-176	572.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
YHH3_k127_3243_3	742727.HMPREF9447_02644	2.703e-174	575.0	COG0639@1|root,COG0639@2|Bacteria,4NZWK@976|Bacteroidetes,2FPXD@200643|Bacteroidia,4ASGR@815|Bacteroidaceae	976|Bacteroidetes	T	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
YHH3_k127_3255726_0	1250006.JHZZ01000001_gene2383	3.007e-173	551.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,1IC3K@117743|Flavobacteriia,3VXCE@52959|Polaribacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_3255726_1	1210884.HG799465_gene11875	3.441e-62	230.0	COG1680@1|root,COG1680@2|Bacteria,2IX14@203682|Planctomycetes	203682|Planctomycetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH3_k127_3255726_2	313628.LNTAR_07629	1.839e-53	202.0	28N0G@1|root,2ZB6W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3255726_3	1121937.AUHJ01000005_gene2343	4.619e-26	113.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria,467QY@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
YHH3_k127_3259844_5	794903.OPIT5_20175	0.000282	54.0	COG1404@1|root,COG1404@2|Bacteria,46VHC@74201|Verrucomicrobia	2|Bacteria	O	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PA,PPC,Peptidase_M36,Peptidase_S8,SLH
YHH3_k127_3259844_4	1304885.AUEY01000096_gene2839	8.585e-10	72.0	COG1404@1|root,COG2304@1|root,COG2911@1|root,COG3897@1|root,COG5434@1|root,COG1404@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3897@2|Bacteria,COG5434@2|Bacteria,1P8N9@1224|Proteobacteria,43DXZ@68525|delta/epsilon subdivisions,2X72D@28221|Deltaproteobacteria,2MNHJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YHH3_k127_3259844_1	1282361.ABAC402_06450	1.003e-28	136.0	COG2755@1|root,COG2755@2|Bacteria,1RDF0@1224|Proteobacteria	1224|Proteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH3_k127_3259844_2	497964.CfE428DRAFT_1649	1.214e-14	90.0	COG3506@1|root,COG4254@1|root,COG3506@2|Bacteria,COG4254@2|Bacteria,46SQ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Lyase_8,Lyase_N,Lyase_catalyt
YHH3_k127_3259844_0	1122927.KB895414_gene5046	4.189e-137	490.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HUM3@91061|Bacilli,26UZS@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_3259844_3	880070.Cycma_0174	6.104e-12	74.0	COG3119@1|root,COG3119@2|Bacteria,4P1UT@976|Bacteroidetes,47XAS@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	3.10.1.1	ko:K01565	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07814	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_3265730_6	1100720.ALKN01000045_gene276	7.051e-11	72.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ6F@28216|Betaproteobacteria,4ADGN@80864|Comamonadaceae	28216|Betaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
YHH3_k127_3265730_2	382464.ABSI01000011_gene2718	1.274e-171	552.0	COG2317@1|root,COG2317@2|Bacteria,46TJB@74201|Verrucomicrobia,2IU0U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Carboxypeptidase Taq (M32) metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M32
YHH3_k127_3265730_0	382464.ABSI01000002_gene4262	4.913e-215	682.0	COG0733@1|root,COG0733@2|Bacteria,46XCF@74201|Verrucomicrobia,2IVFD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
YHH3_k127_3265730_3	452637.Oter_3498	5.596e-141	460.0	COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,3K794@414999|Opitutae	414999|Opitutae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH3_k127_3265730_4	382464.ABSI01000022_gene490	1.812e-75	262.0	COG2890@1|root,COG2890@2|Bacteria,46SZE@74201|Verrucomicrobia,2IU5P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
YHH3_k127_3265730_1	794903.OPIT5_16330	7.763e-191	604.0	COG0148@1|root,COG0148@2|Bacteria,46S7N@74201|Verrucomicrobia,3K7NC@414999|Opitutae	414999|Opitutae	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
YHH3_k127_3279965_1	583355.Caka_1288	1.302e-36	146.0	2AG8J@1|root,316DU@2|Bacteria,46WFQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3279965_2	1144307.PMI04_02525	3.296e-31	131.0	2DNBN@1|root,32WN2@2|Bacteria,1N5BF@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
YHH3_k127_3279965_0	1123508.JH636445_gene6612	7.385e-46	189.0	COG2202@1|root,COG3920@1|root,COG2202@2|Bacteria,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HATPase_c_2,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Pkinase,Response_reg,dCache_1
YHH3_k127_3289816_0	452637.Oter_3766	1.267e-62	243.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_3303595_0	452637.Oter_2368	9.54e-183	599.0	COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia,3K7BA@414999|Opitutae	414999|Opitutae	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH3_k127_330611_2	382464.ABSI01000005_gene1146	2.006e-36	143.0	COG0845@1|root,COG0845@2|Bacteria,46U5P@74201|Verrucomicrobia,2IU9K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YHH3_k127_330611_3	497964.CfE428DRAFT_0077	3.085e-23	114.0	COG1538@1|root,COG1538@2|Bacteria,46T1E@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_330611_1	497964.CfE428DRAFT_0077	4.794e-74	268.0	COG1538@1|root,COG1538@2|Bacteria,46T1E@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_330611_0	452637.Oter_1890	3.165e-132	452.0	COG0577@1|root,COG0577@2|Bacteria,46UZM@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_330611_4	401053.AciPR4_2539	5.754e-06	49.0	COG0577@1|root,COG0577@2|Bacteria,3Y6GK@57723|Acidobacteria,2JKI5@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_3420296_2	103733.JNYO01000060_gene8738	3.413e-59	207.0	COG1082@1|root,COG1082@2|Bacteria,2H1AC@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_3420296_0	869213.JCM21142_3796	2.559e-67	237.0	COG2755@1|root,COG2755@2|Bacteria,4NMPH@976|Bacteroidetes,47VXX@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3420296_1	382464.ABSI01000013_gene1839	7.998e-61	232.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8
YHH3_k127_3431166_0	313628.LNTAR_11691	1.603e-191	634.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH3_k127_3431166_3	1396418.BATQ01000047_gene6218	4.585e-98	332.0	COG2382@1|root,COG2382@2|Bacteria,46UH3@74201|Verrucomicrobia,2IUBH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_48,Esterase
YHH3_k127_3431166_1	1396141.BATP01000023_gene578	5.474e-169	538.0	COG3507@1|root,COG3507@2|Bacteria,46WST@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
YHH3_k127_3431166_4	143224.JQMD01000002_gene167	1.095e-21	101.0	COG3507@1|root,COG3507@2|Bacteria,4NK5P@976|Bacteroidetes,1IIH6@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
YHH3_k127_3431166_2	405948.SACE_4344	5.178e-121	399.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria,4E06M@85010|Pseudonocardiales	201174|Actinobacteria	M	Mandelate racemase muconate lactonizing enzyme	-	-	4.1.2.21,4.2.1.6,4.2.1.8	ko:K01631,ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	M00061,M00552	R01064,R03033,R05606	RC00307,RC00435,RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YHH3_k127_349521_5	1408473.JHXO01000013_gene523	0.0008264	43.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,2FNXA@200643|Bacteroidia	976|Bacteroidetes	E	Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_349521_4	595460.RRSWK_02816	5.104e-24	108.0	COG4799@1|root,COG4799@2|Bacteria,2IY0Q@203682|Planctomycetes	2|Bacteria	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	mmdA	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0716	Carboxyl_trans
YHH3_k127_349521_2	583355.Caka_0800	2.933e-64	223.0	COG0346@1|root,COG0346@2|Bacteria,46VJH@74201|Verrucomicrobia,3K82H@414999|Opitutae	414999|Opitutae	E	Glyoxalase-like domain	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
YHH3_k127_349521_1	1121403.AUCV01000031_gene2833	2.482e-161	533.0	COG1884@1|root,COG1884@2|Bacteria,1NR2K@1224|Proteobacteria,42P1I@68525|delta/epsilon subdivisions,2WKIW@28221|Deltaproteobacteria,2MMUD@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
YHH3_k127_349521_0	649747.HMPREF0083_06147	0.0	1100.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,2726S@186822|Paenibacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
YHH3_k127_349521_3	649747.HMPREF0083_06146	1.303e-42	160.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H9ZJ@91061|Bacilli,2721C@186822|Paenibacillaceae	91061|Bacilli	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
YHH3_k127_3512235_0	382464.ABSI01000012_gene2012	7.01e-131	458.0	COG1629@1|root,COG1629@2|Bacteria,46U2X@74201|Verrucomicrobia	74201|Verrucomicrobia	M	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_3512235_1	1256908.HMPREF0373_02746	1.623e-06	52.0	COG5263@1|root,COG5434@1|root,COG5520@1|root,COG5263@2|Bacteria,COG5434@2|Bacteria,COG5520@2|Bacteria,1TQ4E@1239|Firmicutes,24C60@186801|Clostridia	186801|Clostridia	M	O-Glycosyl hydrolase family 30	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,CW_binding_1,F5_F8_type_C,FIVAR,Glyco_hydr_30_2,Glyco_hydro_43
YHH3_k127_3516921_0	335543.Sfum_1659	7.532e-67	249.0	2C5Z1@1|root,33ZHM@2|Bacteria,1NXTS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3516921_1	748658.KB907319_gene730	7.268e-38	146.0	COG1569@1|root,COG1569@2|Bacteria,1N9YY@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH3_k127_3522894_2	243090.RB13155	2.351e-75	284.0	COG3119@1|root,COG3119@2|Bacteria,2IX69@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_3522894_0	1123070.KB899262_gene1709	9.731e-122	424.0	COG0412@1|root,COG1520@1|root,COG0412@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	3.1.1.101,3.1.1.45	ko:K01061,ko:K21104	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222,R11540	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Calx-beta,Chlorophyllase,Chlorophyllase2,DLH,DUF1566,DUF4114,DUF4347,HemolysinCabind,PQQ_3,Peptidase_S9,RHS_repeat,SLH
YHH3_k127_3522894_1	620914.JH621264_gene1665	5.211e-107	361.0	COG5434@1|root,COG5434@2|Bacteria,4NG4T@976|Bacteroidetes,1IIH4@117743|Flavobacteriia	976|Bacteroidetes	G	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
YHH3_k127_3591148_3	324925.Ppha_2432	6.193e-21	99.0	COG2267@1|root,COG2267@2|Bacteria,1FDX0@1090|Chlorobi	1090|Chlorobi	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
YHH3_k127_3591148_2	382464.ABSI01000005_gene1163	7.269e-64	222.0	COG0652@1|root,COG0652@2|Bacteria,46V73@74201|Verrucomicrobia,2IU91@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
YHH3_k127_3591148_0	1123070.KB899249_gene391	3.929e-131	429.0	COG0369@1|root,COG0369@2|Bacteria,46USZ@74201|Verrucomicrobia,2ITQZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1
YHH3_k127_3591148_1	1123070.KB899253_gene1125	3.604e-104	343.0	COG0021@1|root,COG0021@2|Bacteria,46SHW@74201|Verrucomicrobia,2ITKK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
YHH3_k127_3612885_7	382464.ABSI01000005_gene1167	6.038e-18	85.0	COG0332@1|root,COG0332@2|Bacteria,46UBS@74201|Verrucomicrobia	74201|Verrucomicrobia	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	-	-	-	ko:K22317	-	-	-	-	ko00000	-	-	-	ACP_syn_III,ACP_syn_III_C
YHH3_k127_3612885_4	583355.Caka_1902	3.775e-97	324.0	COG0623@1|root,COG0623@2|Bacteria,46TU1@74201|Verrucomicrobia,3K780@414999|Opitutae	414999|Opitutae	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH3_k127_3612885_5	583355.Caka_1903	7.517e-50	181.0	COG0764@1|root,COG0764@2|Bacteria,46VX8@74201|Verrucomicrobia,3K8BA@414999|Opitutae	414999|Opitutae	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
YHH3_k127_3612885_2	583355.Caka_1758	2.385e-223	701.0	COG1233@1|root,COG1233@2|Bacteria,46YTW@74201|Verrucomicrobia,3K7V6@414999|Opitutae	414999|Opitutae	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
YHH3_k127_3612885_3	452637.Oter_3000	1.782e-143	464.0	COG0075@1|root,COG0075@2|Bacteria,46SCI@74201|Verrucomicrobia,3K7QY@414999|Opitutae	414999|Opitutae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YHH3_k127_3612885_1	452637.Oter_2998	1.113e-270	857.0	COG0550@1|root,COG0550@2|Bacteria,46S97@74201|Verrucomicrobia,3K7FV@414999|Opitutae	414999|Opitutae	L	DNA topoisomerase type IA central domain protein	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
YHH3_k127_3612885_6	794903.OPIT5_30305	2.297e-30	124.0	COG1393@1|root,COG1393@2|Bacteria,46VTP@74201|Verrucomicrobia,3K855@414999|Opitutae	414999|Opitutae	P	Belongs to the ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
YHH3_k127_3612885_0	583355.Caka_1919	0.0	1105.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia,3K79V@414999|Opitutae	414999|Opitutae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH3_k127_3633007_0	452637.Oter_3064	4.974e-106	352.0	COG2730@1|root,COG2730@2|Bacteria,46WXN@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038
YHH3_k127_3633007_1	211165.AJLN01000134_gene5860	5.33e-08	61.0	COG3240@1|root,COG4625@1|root,COG3240@2|Bacteria,COG4625@2|Bacteria,1G2WT@1117|Cyanobacteria,1JKJE@1189|Stigonemataceae	1117|Cyanobacteria	I	Autotransporter beta-domain	-	-	-	ko:K12686	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.8	-	-	Autotransporter,Lipase_GDSL
YHH3_k127_363468_0	657309.BXY_35520	1.767e-123	403.0	28K0D@1|root,2Z9QD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_363468_1	278957.ABEA03000195_gene525	1.095e-57	212.0	COG0111@1|root,COG0111@2|Bacteria,46S96@74201|Verrucomicrobia,3K7KV@414999|Opitutae	2|Bacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
YHH3_k127_363468_3	485917.Phep_3726	4.813e-38	147.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,1IPVP@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_367030_0	880070.Cycma_2886	8.468e-81	284.0	COG0657@1|root,COG0657@2|Bacteria,4NNWF@976|Bacteroidetes,47RDI@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase,Lipase_GDSL_2,Peptidase_S9
YHH3_k127_3678489_7	452637.Oter_2420	3.075e-80	271.0	COG0601@1|root,COG0601@2|Bacteria,46SJN@74201|Verrucomicrobia,3K7V9@414999|Opitutae	414999|Opitutae	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
YHH3_k127_3678489_6	452637.Oter_2419	6.855e-108	357.0	COG1173@1|root,COG1173@2|Bacteria,46SN0@74201|Verrucomicrobia,3K744@414999|Opitutae	414999|Opitutae	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
YHH3_k127_3678489_4	1123070.KB899253_gene1069	7.875e-117	384.0	COG0444@1|root,COG0444@2|Bacteria,46U0J@74201|Verrucomicrobia,2ITGK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
YHH3_k127_3678489_5	452637.Oter_2722	4.293e-108	359.0	COG4608@1|root,COG4608@2|Bacteria,46U8E@74201|Verrucomicrobia,3KA26@414999|Opitutae	414999|Opitutae	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
YHH3_k127_3678489_12	794903.OPIT5_09815	3.534e-31	126.0	COG3536@1|root,COG3536@2|Bacteria,46VNP@74201|Verrucomicrobia,3K8AJ@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
YHH3_k127_3678489_13	452637.Oter_2444	9.059e-29	125.0	COG1102@1|root,COG1102@2|Bacteria,46YNS@74201|Verrucomicrobia,3K9W8@414999|Opitutae	414999|Opitutae	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
YHH3_k127_3678489_1	382464.ABSI01000013_gene1747	8.626e-160	525.0	COG0488@1|root,COG0488@2|Bacteria,46V06@74201|Verrucomicrobia,2IU2D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH3_k127_3678489_8	1298865.H978DRAFT_0984	4.295e-47	194.0	COG4773@1|root,COG4773@2|Bacteria,1NXPR@1224|Proteobacteria,1RSBC@1236|Gammaproteobacteria,466AC@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH3_k127_3678489_0	1442599.JAAN01000014_gene3505	8.032e-176	561.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1X3P1@135614|Xanthomonadales	135614|Xanthomonadales	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
YHH3_k127_3678489_10	452637.Oter_3483	1.082e-40	157.0	COG1376@1|root,COG1376@2|Bacteria,46VRV@74201|Verrucomicrobia,3K809@414999|Opitutae	414999|Opitutae	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
YHH3_k127_3678489_2	382464.ABSI01000010_gene3596	1.401e-136	446.0	COG0136@1|root,COG0136@2|Bacteria,46S74@74201|Verrucomicrobia,2ITM6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YHH3_k127_3678489_3	1163617.SCD_n02853	8.977e-133	435.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
YHH3_k127_3678489_15	1408444.JHYC01000013_gene2473	0.0001682	46.0	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3678489_11	1195236.CTER_4578	2.64e-32	141.0	COG1262@1|root,COG1262@2|Bacteria,1V03B@1239|Firmicutes,249WZ@186801|Clostridia	186801|Clostridia	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
YHH3_k127_3678489_9	452637.Oter_3503	3.692e-41	158.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_3678489_14	452637.Oter_3721	2.088e-23	111.0	COG3712@1|root,COG3712@2|Bacteria,46VY1@74201|Verrucomicrobia,3K8T5@414999|Opitutae	414999|Opitutae	PT	Anti-FecI sigma factor, FecR	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
YHH3_k127_3680154_0	1124780.ANNU01000002_gene1469	2.473e-35	144.0	COG1361@1|root,COG2706@1|root,COG1361@2|Bacteria,COG2706@2|Bacteria,4PPMM@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
YHH3_k127_3680154_1	1408813.AYMG01000032_gene5239	5.872e-10	69.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IR0W@117747|Sphingobacteriia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,SASA,SprB
YHH3_k127_3686719_12	583355.Caka_2107	1.643e-25	109.0	COG0711@1|root,COG0711@2|Bacteria,46SYI@74201|Verrucomicrobia,3K89M@414999|Opitutae	414999|Opitutae	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
YHH3_k127_3686719_15	583355.Caka_2108	1.412e-09	64.0	COG0712@1|root,COG0712@2|Bacteria,46TC4@74201|Verrucomicrobia,3K886@414999|Opitutae	414999|Opitutae	C	ATP synthase delta (OSCP) subunit	-	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
YHH3_k127_3686719_1	382464.ABSI01000012_gene2278	2.901e-242	756.0	COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia,2ITR0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
YHH3_k127_3686719_5	452637.Oter_0876	1.42e-93	315.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia,3K742@414999|Opitutae	414999|Opitutae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
YHH3_k127_3686719_0	382464.ABSI01000012_gene2280	1.39e-244	762.0	COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia,2IU0R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH3_k127_3686719_13	452637.Oter_0874	2.111e-24	108.0	COG0355@1|root,COG0355@2|Bacteria,46T0F@74201|Verrucomicrobia,3K83V@414999|Opitutae	414999|Opitutae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
YHH3_k127_3686719_7	794903.OPIT5_25535	5.434e-71	245.0	2C0ZJ@1|root,33VV4@2|Bacteria,46VGY@74201|Verrucomicrobia,3K7JZ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3686719_8	452637.Oter_4554	2.186e-68	241.0	COG1043@1|root,COG1043@2|Bacteria,46V8M@74201|Verrucomicrobia,3K837@414999|Opitutae	414999|Opitutae	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
YHH3_k127_3686719_9	935261.JAGL01000016_gene2779	8.972e-66	236.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,43HEP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
YHH3_k127_3686719_11	452637.Oter_4552	4.888e-41	154.0	COG0316@1|root,COG0316@2|Bacteria,46T1T@74201|Verrucomicrobia,3K842@414999|Opitutae	414999|Opitutae	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
YHH3_k127_3686719_4	452637.Oter_1765	6.642e-108	353.0	COG1215@1|root,COG1215@2|Bacteria,46SRA@74201|Verrucomicrobia,3K7C7@414999|Opitutae	414999|Opitutae	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_3686719_2	583355.Caka_0857	5.284e-145	475.0	COG0591@1|root,COG0591@2|Bacteria,46ZB9@74201|Verrucomicrobia,3K8WD@414999|Opitutae	414999|Opitutae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_3686719_6	452637.Oter_3856	1.038e-83	295.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,46VFJ@74201|Verrucomicrobia,3K8TA@414999|Opitutae	414999|Opitutae	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YHH3_k127_3686719_3	1499967.BAYZ01000048_gene2713	6.371e-118	397.0	COG2103@1|root,COG2103@2|Bacteria,2NP6Y@2323|unclassified Bacteria	2|Bacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
YHH3_k127_3686719_14	273068.TTE2678	3.022e-13	79.0	COG0775@1|root,COG0775@2|Bacteria,1VCJY@1239|Firmicutes,24CRR@186801|Clostridia,42GAC@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM purine or other phosphorylase, family 1	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
YHH3_k127_3686719_10	1121335.Clst_1964	5.161e-48	176.0	COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,249NM@186801|Clostridia	186801|Clostridia	L	Spore photoproduct lyase	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
YHH3_k127_3690717_5	1328313.DS2_15344	3.857e-10	62.0	2DBDK@1|root,2Z8MH@2|Bacteria,1NQMX@1224|Proteobacteria,1SK90@1236|Gammaproteobacteria,469CE@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
YHH3_k127_3690717_2	583355.Caka_0090	4.053e-56	209.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
YHH3_k127_3690717_0	595460.RRSWK_03620	5.562e-252	793.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_3690717_4	1042376.AFPK01000016_gene1950	1.156e-18	90.0	COG3119@1|root,COG3119@2|Bacteria,4PHTG@976|Bacteroidetes,1I830@117743|Flavobacteriia	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_3690717_3	1296416.JACB01000026_gene4017	5.054e-56	200.0	COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,1HZT1@117743|Flavobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,SLC12
YHH3_k127_369768_0	247634.GPB2148_1962	4.313e-61	224.0	COG0121@1|root,COG0121@2|Bacteria,1Q80V@1224|Proteobacteria,1SN0H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphoinositide phospholipase C, Ca2+-dependent	-	-	-	-	-	-	-	-	-	-	-	-	PI-PLC-C1
YHH3_k127_369768_1	1005048.CFU_0337	1.339e-30	130.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,2VZ3T@28216|Betaproteobacteria,474N6@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
YHH3_k127_3703249_0	760192.Halhy_3122	2.109e-21	96.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K04767,ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
YHH3_k127_3703249_2	1410631.JHWZ01000002_gene1350	8.937e-05	54.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,27PJ6@186928|unclassified Lachnospiraceae	186801|Clostridia	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
YHH3_k127_3703249_1	714943.Mucpa_2702	6.587e-13	80.0	COG0589@1|root,COG0589@2|Bacteria,4NPYE@976|Bacteroidetes,1ISGK@117747|Sphingobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YHH3_k127_3713431_0	1265503.KB905160_gene2790	2.845e-144	469.0	COG3119@1|root,COG3119@2|Bacteria,1NQY5@1224|Proteobacteria,1SJJN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
YHH3_k127_3713431_1	358396.C445_02311	2.909e-43	169.0	COG3119@1|root,arCOG02785@2157|Archaea,2XTTU@28890|Euryarchaeota,23UC8@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_3726357_1	382464.ABSI01000014_gene1433	1.042e-151	487.0	COG3288@1|root,COG3288@2|Bacteria,46SFW@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
YHH3_k127_3726357_3	589873.EP13_18250	5.283e-30	121.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,1S9UK@1236|Gammaproteobacteria,4682B@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	NAD NADP transhydrogenase alpha subunit	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
YHH3_k127_3726357_0	1117647.M5M_11445	3.413e-163	526.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,1J5AS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
YHH3_k127_3726357_2	452637.Oter_3077	7.878e-50	193.0	COG2982@1|root,COG2982@2|Bacteria,46VEJ@74201|Verrucomicrobia,3K8PP@414999|Opitutae	414999|Opitutae	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
YHH3_k127_3770226_1	240016.ABIZ01000001_gene1396	7.052e-97	321.0	COG0155@1|root,COG0155@2|Bacteria,46U85@74201|Verrucomicrobia,2ITJ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
YHH3_k127_3770226_0	583355.Caka_1761	7.405e-186	594.0	COG1966@1|root,COG1966@2|Bacteria,46V26@74201|Verrucomicrobia,3K9J7@414999|Opitutae	414999|Opitutae	T	PFAM carbon starvation protein CstA	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
YHH3_k127_3770226_2	583355.Caka_1760	2.595e-27	113.0	COG0232@1|root,COG0232@2|Bacteria,46UHP@74201|Verrucomicrobia,3K787@414999|Opitutae	414999|Opitutae	F	Deoxyguanosinetriphosphate triphosphohydrolase	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
YHH3_k127_3774835_4	452637.Oter_2787	8.143e-36	143.0	COG0739@1|root,COG0739@2|Bacteria,46V20@74201|Verrucomicrobia,3K74E@414999|Opitutae	414999|Opitutae	M	Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH3_k127_3774835_1	583355.Caka_2975	7.155e-87	302.0	2DRTQ@1|root,32URN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3774835_0	583355.Caka_2976	4.177e-157	500.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,3K7P4@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
YHH3_k127_3774835_5	794903.OPIT5_01065	7.237e-28	116.0	COG0457@1|root,COG0457@2|Bacteria,46Z69@74201|Verrucomicrobia,3K8AP@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3774835_3	278957.ABEA03000206_gene3777	3.419e-48	177.0	COG0735@1|root,COG0735@2|Bacteria,46V9Y@74201|Verrucomicrobia,3K81W@414999|Opitutae	414999|Opitutae	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH3_k127_3774835_7	452637.Oter_0178	2.854e-08	62.0	295DN@1|root,2ZSRI@2|Bacteria,46WWE@74201|Verrucomicrobia,3K80Z@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3774835_2	583355.Caka_1855	5.025e-51	184.0	COG1327@1|root,COG1327@2|Bacteria,46VCN@74201|Verrucomicrobia,3K7XU@414999|Opitutae	414999|Opitutae	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
YHH3_k127_3774835_6	452637.Oter_2721	1.383e-26	110.0	COG0219@1|root,COG0219@2|Bacteria,46SYZ@74201|Verrucomicrobia,3K7ZG@414999|Opitutae	414999|Opitutae	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	-	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
YHH3_k127_3784979_1	2002.JOEQ01000001_gene4838	0.0001077	50.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3784979_0	1121456.ATVA01000019_gene1268	1.155e-79	289.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_4,PAS_9,dCache_1
YHH3_k127_3799232_2	156889.Mmc1_2179	6.998e-06	61.0	COG1357@1|root,COG2931@1|root,COG3184@1|root,COG1357@2|Bacteria,COG2931@2|Bacteria,COG3184@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Collar,HemolysinCabind,Peptidase_M10_C
YHH3_k127_3799232_1	111780.Sta7437_2479	7.835e-49	203.0	COG1075@1|root,COG2931@1|root,COG1075@2|Bacteria,COG2931@2|Bacteria,1G1I0@1117|Cyanobacteria	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,HemolysinCabind,P_proprotein,Peptidase_S8
YHH3_k127_3799232_0	1403819.BATR01000059_gene1813	1.466e-50	186.0	COG1136@1|root,COG1136@2|Bacteria,46VGE@74201|Verrucomicrobia,2IVNT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YHH3_k127_3803458_5	713587.THITH_07425	6.929e-28	116.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1SMH6@1236|Gammaproteobacteria,1X0JB@135613|Chromatiales	135613|Chromatiales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YHH3_k127_3803458_3	643867.Ftrac_0701	8.361e-69	243.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,47PIS@768503|Cytophagia	976|Bacteroidetes	M	Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YHH3_k127_3803458_8	583355.Caka_0882	2.419e-12	79.0	COG0803@1|root,COG0803@2|Bacteria	2|Bacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815,ko:K15727	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5,8.A.1.2.1	-	-	HlyD_D23,ZnuA
YHH3_k127_3803458_6	382464.ABSI01000005_gene1197	1.867e-27	115.0	COG0476@1|root,COG0476@2|Bacteria,46SGF@74201|Verrucomicrobia,2IU1E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
YHH3_k127_3803458_0	583355.Caka_2492	1.841e-132	432.0	COG0836@1|root,COG0836@2|Bacteria,46UR9@74201|Verrucomicrobia,3K7G3@414999|Opitutae	414999|Opitutae	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
YHH3_k127_3803458_4	382464.ABSI01000005_gene1199	3.136e-47	174.0	COG0816@1|root,COG0816@2|Bacteria,46T51@74201|Verrucomicrobia,2IUHN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Likely ribonuclease with RNase H fold.	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
YHH3_k127_3803458_2	794903.OPIT5_19920	1.508e-81	278.0	COG0101@1|root,COG0101@2|Bacteria,46SSV@74201|Verrucomicrobia,3K80Q@414999|Opitutae	414999|Opitutae	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
YHH3_k127_3803458_1	573370.DMR_01830	1.436e-124	414.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2M93H@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
YHH3_k127_3803458_7	935837.JAEK01000015_gene5068	1.21e-18	93.0	COG0803@1|root,COG3443@1|root,COG0803@2|Bacteria,COG3443@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,1ZC2Z@1386|Bacillus	91061|Bacilli	P	Belongs to the bacterial solute-binding protein 9 family	zinT	-	-	ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZinT,ZnuA
YHH3_k127_3809278_6	1137281.D778_01668	1.115e-21	112.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes,1IKH7@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Sortilin-Vps10
YHH3_k127_3809278_7	452637.Oter_0313	9.995e-07	63.0	COG1520@1|root,COG3291@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,46Z5C@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	Ig_3
YHH3_k127_3809278_8	1396141.BATP01000022_gene416	3.958e-06	61.0	COG1404@1|root,COG1572@1|root,COG4733@1|root,COG5184@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,46TRJ@74201|Verrucomicrobia	74201|Verrucomicrobia	DZ	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF5122
YHH3_k127_3809278_1	502025.Hoch_5743	1.242e-287	894.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42NJZ@68525|delta/epsilon subdivisions,2WK1Q@28221|Deltaproteobacteria,2YZK2@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
YHH3_k127_3809278_5	502025.Hoch_5742	2.715e-26	111.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,42VFF@68525|delta/epsilon subdivisions,2WR8E@28221|Deltaproteobacteria,2Z2T8@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
YHH3_k127_3809278_4	583355.Caka_1802	7.128e-77	265.0	COG1388@1|root,COG1388@2|Bacteria,46T61@74201|Verrucomicrobia,3K9J0@414999|Opitutae	414999|Opitutae	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LysM
YHH3_k127_3809278_0	583355.Caka_2853	6.201e-306	949.0	COG0556@1|root,COG0556@2|Bacteria,46SF2@74201|Verrucomicrobia,3K76Z@414999|Opitutae	414999|Opitutae	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH3_k127_3809278_2	1535422.ND16A_1300	1.83e-143	467.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,2Q6M0@267889|Colwelliaceae	1236|Gammaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
YHH3_k127_3809278_3	1129374.AJE_13150	6.326e-100	332.0	COG3007@1|root,COG3007@2|Bacteria,1MWCQ@1224|Proteobacteria,1RPPP@1236|Gammaproteobacteria,4657U@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP)	fabV	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
YHH3_k127_3816573_1	583355.Caka_2548	3.98e-05	49.0	28IN0@1|root,2Z8NG@2|Bacteria,46W43@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Glycosyltransferase family 10 (fucosyltransferase) C-term	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_10
YHH3_k127_3816573_0	565045.NOR51B_761	3.112e-79	280.0	COG2244@1|root,COG2244@2|Bacteria,1MUN5@1224|Proteobacteria,1RRAJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	wzx	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
YHH3_k127_3837820_3	583355.Caka_1554	1.345e-19	91.0	COG2839@1|root,COG2839@2|Bacteria,46WB1@74201|Verrucomicrobia,3K8HU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
YHH3_k127_3837820_1	583355.Caka_1402	3.642e-72	252.0	COG3228@1|root,COG3228@2|Bacteria	2|Bacteria	S	metallopeptidase activity	mtfA	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90,SEC-C
YHH3_k127_3837820_4	378806.STAUR_6725	1.646e-17	89.0	COG1846@1|root,COG1846@2|Bacteria,1N1RV@1224|Proteobacteria,42WMS@68525|delta/epsilon subdivisions,2WR99@28221|Deltaproteobacteria,2Z2BS@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
YHH3_k127_3837820_0	1121405.dsmv_1698	1.933e-85	302.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,2MKQU@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
YHH3_k127_3837820_2	1232410.KI421412_gene178	1.314e-54	195.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43S5E@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YHH3_k127_385152_9	517418.Ctha_0424	4.702e-19	90.0	COG2331@1|root,COG2331@2|Bacteria,1FE7Y@1090|Chlorobi	1090|Chlorobi	S	TIGRFAM regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH3_k127_385152_12	583355.Caka_1125	1.235e-10	70.0	2A1DB@1|root,30PKC@2|Bacteria,46WF1@74201|Verrucomicrobia,3K8HN@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
YHH3_k127_385152_2	583355.Caka_1126	7.442e-93	313.0	COG0142@1|root,COG0142@2|Bacteria,46S62@74201|Verrucomicrobia,3K7Y1@414999|Opitutae	414999|Opitutae	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH3_k127_385152_3	794903.OPIT5_02080	3.219e-80	271.0	COG0740@1|root,COG0740@2|Bacteria,46TSB@74201|Verrucomicrobia,3K79J@414999|Opitutae	414999|Opitutae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YHH3_k127_385152_7	382464.ABSI01000005_gene1092	3.399e-56	202.0	COG0290@1|root,COG0290@2|Bacteria,46SU6@74201|Verrucomicrobia,2IUB3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	-	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
YHH3_k127_385152_4	583355.Caka_0842	5.135e-79	275.0	COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia,3K7YX@414999|Opitutae	414999|Opitutae	M	cell wall hydrolase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
YHH3_k127_385152_10	649747.HMPREF0083_00213	1.942e-16	83.0	COG0239@1|root,COG0239@2|Bacteria,1VEH7@1239|Firmicutes,4HNI0@91061|Bacilli,26ZZT@186822|Paenibacillaceae	91061|Bacilli	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
YHH3_k127_385152_11	1122201.AUAZ01000008_gene483	2.638e-15	81.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,467ZU@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
YHH3_k127_385152_1	452637.Oter_4546	3.367e-98	341.0	COG0457@1|root,COG0457@2|Bacteria,46SRS@74201|Verrucomicrobia,3K7VK@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_385152_0	583355.Caka_2205	2.878e-299	948.0	COG0022@1|root,COG0508@1|root,COG1071@1|root,COG0022@2|Bacteria,COG0508@2|Bacteria,COG1071@2|Bacteria,46TPF@74201|Verrucomicrobia,3K7MS@414999|Opitutae	414999|Opitutae	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
YHH3_k127_385152_5	1121918.ARWE01000001_gene615	6.842e-78	264.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
YHH3_k127_385152_8	1246459.KB898361_gene5637	9.566e-30	121.0	2DCU1@1|root,32U0B@2|Bacteria,1N1AS@1224|Proteobacteria,2UCVB@28211|Alphaproteobacteria,4BFMA@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
YHH3_k127_385152_6	517418.Ctha_0502	1.111e-57	206.0	COG0577@1|root,COG0577@2|Bacteria,1FDCY@1090|Chlorobi	1090|Chlorobi	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
YHH3_k127_3857197_3	452637.Oter_0644	1.512e-109	386.0	COG1074@1|root,COG1074@2|Bacteria,46SF0@74201|Verrucomicrobia,3K7V5@414999|Opitutae	414999|Opitutae	L	PD-(D/E)XK nuclease superfamily	-	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH3_k127_3857197_2	583355.Caka_2871	1.664e-110	368.0	COG0042@1|root,COG0042@2|Bacteria,46TCT@74201|Verrucomicrobia,3K895@414999|Opitutae	414999|Opitutae	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
YHH3_k127_3857197_1	502025.Hoch_6864	1.005e-131	441.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2Z1IJ@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YHH3_k127_3857197_0	385682.AFSL01000014_gene2765	1.938e-193	616.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,2FMB0@200643|Bacteroidia,3XK9P@558415|Marinilabiliaceae	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
YHH3_k127_3857197_4	1265503.KB905160_gene2778	2.168e-101	340.0	COG3119@1|root,COG3119@2|Bacteria,1RJ6J@1224|Proteobacteria,1S66X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_3862151_7	1396418.BATQ01000157_gene2416	3.823e-29	120.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
YHH3_k127_3862151_4	313628.LNTAR_00920	4.129e-102	348.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
YHH3_k127_3862151_0	595460.RRSWK_05468	1.494e-245	772.0	COG0412@1|root,COG1554@1|root,COG0412@2|Bacteria,COG1554@2|Bacteria,2J2CS@203682|Planctomycetes	203682|Planctomycetes	Q	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,DLH
YHH3_k127_3862151_6	1122915.AUGY01000031_gene7550	3.69e-39	158.0	COG0667@1|root,COG0667@2|Bacteria,1UHXA@1239|Firmicutes,4HDI7@91061|Bacilli,26U1C@186822|Paenibacillaceae	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_3862151_3	143224.JQMD01000002_gene121	1.018e-109	371.0	COG3119@1|root,COG3119@2|Bacteria,4NE6V@976|Bacteroidetes,1HZ00@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_3862151_2	471853.Bcav_3980	3.977e-137	454.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
YHH3_k127_3862151_8	661478.OP10G_0633	5.315e-20	103.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
YHH3_k127_3862151_9	452637.Oter_3546	2.855e-05	51.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
YHH3_k127_3862151_5	521674.Plim_2548	4.115e-86	299.0	COG0329@1|root,COG0329@2|Bacteria,2IX4Y@203682|Planctomycetes	203682|Planctomycetes	H	COG0329 Dihydrodipicolinate synthase N-acetylneuraminate lyase	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YHH3_k127_3862151_1	1347342.BN863_19310	3.474e-170	546.0	2EXP7@1|root,33QYX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3888789_3	452637.Oter_0385	1.664e-13	80.0	COG0810@1|root,COG0810@2|Bacteria,46WNS@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH3_k127_3888789_4	177437.HRM2_00040	6.747e-10	69.0	COG0810@1|root,COG0810@2|Bacteria,1R4VE@1224|Proteobacteria,42SEP@68525|delta/epsilon subdivisions,2WPUA@28221|Deltaproteobacteria,2MK7X@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH3_k127_3888789_2	1449063.JMLS01000001_gene4203	7.189e-37	151.0	COG1082@1|root,COG1082@2|Bacteria,1UYRD@1239|Firmicutes,4I74C@91061|Bacilli,26VZH@186822|Paenibacillaceae	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_3888789_0	794903.OPIT5_23690	2.658e-77	267.0	COG0363@1|root,COG0363@2|Bacteria,46VNG@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
YHH3_k127_3888789_1	886293.Sinac_5304	2.463e-57	207.0	COG0477@1|root,COG2814@2|Bacteria,2IY3A@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
YHH3_k127_3917975_2	314278.NB231_05936	1.55e-10	70.0	291NB@1|root,2ZP8I@2|Bacteria,1P5ZB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
YHH3_k127_3917975_0	1123501.KB902299_gene3713	2.022e-32	130.0	COG0346@1|root,COG0346@2|Bacteria,1RKFI@1224|Proteobacteria,2UBE8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Lactoylglutathione lyase	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
YHH3_k127_3917975_1	1379698.RBG1_1C00001G0813	2.962e-29	120.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
YHH3_k127_3921690_1	998674.ATTE01000001_gene3539	4.079e-155	491.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,1RP49@1236|Gammaproteobacteria,461NK@72273|Thiotrichales	72273|Thiotrichales	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
YHH3_k127_3921690_0	1198232.CYCME_0979	2.391e-177	563.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,1RP8C@1236|Gammaproteobacteria,460CW@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	-	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
YHH3_k127_3921690_2	1198232.CYCME_0980	2.166e-127	413.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RMH5@1236|Gammaproteobacteria,4617A@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
YHH3_k127_3921690_3	583355.Caka_1750	6.486e-91	306.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,3K7DV@414999|Opitutae	414999|Opitutae	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
YHH3_k127_394167_1	468556.AQYG01000051_gene2438	5.996e-06	56.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4GATG@85026|Gordoniaceae	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YHH3_k127_394167_0	583355.Caka_1188	1.815e-293	925.0	COG1643@1|root,COG1643@2|Bacteria,46TFT@74201|Verrucomicrobia,3K75C@414999|Opitutae	414999|Opitutae	L	Helicase associated domain (HA2)  Add an annotation	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
YHH3_k127_3943161_4	583355.Caka_1316	3.543e-118	394.0	COG0265@1|root,COG0265@2|Bacteria,46UW8@74201|Verrucomicrobia,3K7DR@414999|Opitutae	414999|Opitutae	M	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH3_k127_3943161_2	794903.OPIT5_30135	2.655e-131	425.0	COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,3K7RG@414999|Opitutae	414999|Opitutae	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
YHH3_k127_3943161_5	452637.Oter_2336	4.947e-89	305.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia,3K7IB@414999|Opitutae	414999|Opitutae	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
YHH3_k127_3943161_11	1123070.KB899251_gene694	5.288e-10	68.0	COG2825@1|root,COG2825@2|Bacteria,46T22@74201|Verrucomicrobia,2IUS2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
YHH3_k127_3943161_0	452637.Oter_2334	3.19e-237	757.0	COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia,3K73M@414999|Opitutae	414999|Opitutae	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YHH3_k127_3943161_3	583355.Caka_1584	1.564e-129	428.0	COG0305@1|root,COG0305@2|Bacteria,46SKM@74201|Verrucomicrobia,3K7R2@414999|Opitutae	414999|Opitutae	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
YHH3_k127_3943161_6	452637.Oter_2332	2.403e-51	186.0	COG0359@1|root,COG0359@2|Bacteria,46SYE@74201|Verrucomicrobia,3K82A@414999|Opitutae	414999|Opitutae	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
YHH3_k127_3943161_7	583355.Caka_1586	6.934e-45	168.0	COG0629@1|root,COG0629@2|Bacteria,46VZR@74201|Verrucomicrobia,3K80H@414999|Opitutae	414999|Opitutae	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YHH3_k127_3943161_10	452637.Oter_2287	8.71e-14	75.0	COG0360@1|root,COG0360@2|Bacteria,46TBG@74201|Verrucomicrobia,3K8BM@414999|Opitutae	414999|Opitutae	J	Ribosomal protein S6	-	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
YHH3_k127_3943161_8	583355.Caka_1588	1.549e-43	166.0	COG0193@1|root,COG0193@2|Bacteria,46T09@74201|Verrucomicrobia,3K7ZI@414999|Opitutae	414999|Opitutae	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
YHH3_k127_3943161_9	382464.ABSI01000023_gene533	1.55e-34	141.0	COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia,2IUP1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
YHH3_k127_3943161_1	382464.ABSI01000013_gene1535	1.361e-142	458.0	COG4948@1|root,COG4948@2|Bacteria,46VZI@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
YHH3_k127_3947139_0	926569.ANT_20880	3.675e-101	343.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH3_k127_3947139_1	926569.ANT_19050	7.11e-14	75.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,2G62P@200795|Chloroflexi	200795|Chloroflexi	L	HhH-GPD family	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
YHH3_k127_3959907_2	794903.OPIT5_08095	7.48e-138	445.0	COG4864@1|root,COG4864@2|Bacteria,46TWZ@74201|Verrucomicrobia,3K7TX@414999|Opitutae	414999|Opitutae	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
YHH3_k127_3959907_15	1235803.C825_00489	9.131e-07	57.0	COG1030@1|root,COG1030@2|Bacteria,4NGGV@976|Bacteroidetes,2FP4N@200643|Bacteroidia,22X22@171551|Porphyromonadaceae	976|Bacteroidetes	O	serine protease	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,Peptidase_S49,SDH_sah
YHH3_k127_3959907_4	794903.OPIT5_08085	1.871e-112	379.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia,3K7B8@414999|Opitutae	414999|Opitutae	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
YHH3_k127_3959907_5	497964.CfE428DRAFT_4021	2.115e-112	374.0	COG1600@1|root,COG1600@2|Bacteria,46SDV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
YHH3_k127_3959907_9	1127673.GLIP_2889	8.574e-59	209.0	COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,1RQWI@1236|Gammaproteobacteria,466Z3@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YHH3_k127_3959907_11	794903.OPIT5_04420	4.86e-37	143.0	COG0346@1|root,COG0346@2|Bacteria,46VWN@74201|Verrucomicrobia,3K8EY@414999|Opitutae	414999|Opitutae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
YHH3_k127_3959907_12	1121930.AQXG01000002_gene2081	7.016e-27	112.0	COG2840@1|root,COG2840@2|Bacteria	2|Bacteria	U	Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
YHH3_k127_3959907_1	452637.Oter_3359	6.075e-215	694.0	COG1643@1|root,COG1643@2|Bacteria,46TMT@74201|Verrucomicrobia,3K7J2@414999|Opitutae	414999|Opitutae	L	ATP-dependent helicase C-terminal	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
YHH3_k127_3959907_3	583355.Caka_2099	4.678e-134	441.0	COG0486@1|root,COG0486@2|Bacteria,46SIQ@74201|Verrucomicrobia,3K7N8@414999|Opitutae	414999|Opitutae	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
YHH3_k127_3959907_0	583355.Caka_2100	2.088e-271	847.0	COG0445@1|root,COG0445@2|Bacteria,46SID@74201|Verrucomicrobia,3K7JB@414999|Opitutae	414999|Opitutae	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
YHH3_k127_3959907_7	583355.Caka_2101	1.95e-89	302.0	COG0745@1|root,COG0745@2|Bacteria,46SS3@74201|Verrucomicrobia,3K7XM@414999|Opitutae	414999|Opitutae	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH3_k127_3959907_8	583355.Caka_2102	1.93e-81	287.0	COG5002@1|root,COG5002@2|Bacteria,46SSA@74201|Verrucomicrobia,3K7XI@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
YHH3_k127_3959907_10	382464.ABSI01000012_gene2272	4.311e-45	170.0	COG0220@1|root,COG0220@2|Bacteria,46T5A@74201|Verrucomicrobia,2IUBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Putative methyltransferase	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
YHH3_k127_3959907_6	583355.Caka_2105	3.392e-105	349.0	COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia,3K7XV@414999|Opitutae	414999|Opitutae	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
YHH3_k127_3959907_13	794903.OPIT5_11695	5.707e-24	102.0	2BFTV@1|root,329NU@2|Bacteria,46Z0C@74201|Verrucomicrobia,3K8FB@414999|Opitutae	414999|Opitutae	S	PFAM H transporting two-sector ATPase C subunit	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
YHH3_k127_3959907_14	583355.Caka_2107	3.925e-15	78.0	COG0711@1|root,COG0711@2|Bacteria,46SYI@74201|Verrucomicrobia,3K89M@414999|Opitutae	414999|Opitutae	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
YHH3_k127_3989951_2	1121921.KB898706_gene2451	1.047e-25	107.0	COG2115@1|root,COG2115@2|Bacteria,1MXS2@1224|Proteobacteria,1RN5Y@1236|Gammaproteobacteria,2PN5A@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	iECO26_1355.ECO26_5036,iPC815.YPO4038	-
YHH3_k127_3989951_0	502025.Hoch_0072	9.398e-218	692.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2YY6V@29|Myxococcales	28221|Deltaproteobacteria	C	Pyruvate flavodoxin ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
YHH3_k127_3989951_1	530564.Psta_0806	2.05e-127	417.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
YHH3_k127_399065_1	452637.Oter_3823	4.664e-71	256.0	COG3693@1|root,COG3934@1|root,COG3693@2|Bacteria,COG3934@2|Bacteria,46S7C@74201|Verrucomicrobia,3K7ED@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_399065_3	1343739.PAP_07285	1.052e-10	75.0	arCOG04615@1|root,arCOG04615@2157|Archaea,2Y2IE@28890|Euryarchaeota,244Z1@183968|Thermococci	183968|Thermococci	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_399065_0	314230.DSM3645_01936	8.71e-145	473.0	COG3119@1|root,COG3119@2|Bacteria,2IXH3@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_399065_2	1203611.KB894543_gene1847	2.749e-35	136.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,2FPXE@200643|Bacteroidia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
YHH3_k127_4005865_0	583355.Caka_3039	6.662e-177	567.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46UC1@74201|Verrucomicrobia,3K9FB@414999|Opitutae	414999|Opitutae	C	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4005865_1	595460.RRSWK_03378	6.899e-35	137.0	COG3119@1|root,COG3119@2|Bacteria,2J24M@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_4020007_0	1121904.ARBP01000027_gene738	5.134e-158	512.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_4045321_0	452637.Oter_1890	9.363e-144	480.0	COG0577@1|root,COG0577@2|Bacteria,46UZM@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_4045389_2	497965.Cyan7822_3362	2.391e-16	87.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,VPEP
YHH3_k127_4045389_0	459349.CLOAM1312	3.395e-136	458.0	COG1404@1|root,COG1404@2|Bacteria,2NPDC@2323|unclassified Bacteria	2|Bacteria	O	Peptidase S8	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH3_k127_4045389_1	269797.Mbar_A1955	9.587e-18	98.0	COG3291@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea	2157|Archaea	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,Malectin,PKD,Peptidase_C1
YHH3_k127_4092087_1	583355.Caka_0206	6.436e-83	280.0	COG0641@1|root,COG0641@2|Bacteria,46TC0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	-
YHH3_k127_4092087_2	382464.ABSI01000005_gene1187	1.665e-81	277.0	COG2003@1|root,COG2003@2|Bacteria,46STQ@74201|Verrucomicrobia,2IU7T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
YHH3_k127_4092087_5	237368.SCABRO_00288	9.766e-49	178.0	2DNV7@1|root,32ZAW@2|Bacteria,2J4XF@203682|Planctomycetes	203682|Planctomycetes	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
YHH3_k127_4092087_4	1449351.RISW2_12610	1.043e-53	194.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,2U595@28211|Alphaproteobacteria,4KMIY@93682|Roseivivax	28211|Alphaproteobacteria	T	GAF domain	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
YHH3_k127_4092087_3	1121940.AUDZ01000006_gene228	8.914e-54	194.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1XJUJ@135619|Oceanospirillales	135619|Oceanospirillales	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
YHH3_k127_4092087_8	1499689.CCNN01000007_gene1915	5.182e-11	70.0	COG3837@1|root,COG3837@2|Bacteria,1V9M6@1239|Firmicutes,24HEN@186801|Clostridia,36J6K@31979|Clostridiaceae	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YHH3_k127_4092087_0	497964.CfE428DRAFT_0927	5.061e-173	556.0	COG0644@1|root,COG0644@2|Bacteria,46TJ0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
YHH3_k127_4092087_7	96561.Dole_2781	4.325e-17	89.0	COG0398@1|root,COG0398@2|Bacteria,1N978@1224|Proteobacteria,42W9K@68525|delta/epsilon subdivisions,2WSC4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4092087_6	1121918.ARWE01000001_gene3128	1.843e-20	93.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,42V26@68525|delta/epsilon subdivisions,2WQ0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	acpP-1	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
YHH3_k127_4146678_0	382464.ABSI01000005_gene1295	1.312e-59	211.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YHH3_k127_4146678_1	382464.ABSI01000007_gene4166	1.574e-21	111.0	COG1629@1|root,COG1629@2|Bacteria,46UNV@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_4151727_1	28444.JODQ01000012_gene3420	4.035e-07	58.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42,Glyco_hydro_42M
YHH3_k127_4151727_0	583355.Caka_0472	2.689e-107	363.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
YHH3_k127_4182118_1	316274.Haur_2582	1.667e-16	91.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4234,FHA,GAF,GAF_2,Guanylate_cyc,HATPase_c,Yop-YscD_cpl
YHH3_k127_4182118_0	926569.ANT_31280	1.141e-55	199.0	COG4087@1|root,COG4087@2|Bacteria,2G99M@200795|Chloroflexi	200795|Chloroflexi	S	Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
YHH3_k127_4190315_2	485917.Phep_2212	1.263e-70	249.0	COG3055@1|root,COG3055@2|Bacteria,4NP3D@976|Bacteroidetes,1IQD4@117747|Sphingobacteriia	976|Bacteroidetes	S	Cyclically-permuted mutarotase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4
YHH3_k127_4190315_0	1408813.AYMG01000020_gene2955	8.491e-84	288.0	COG0329@1|root,COG0329@2|Bacteria,4NHBA@976|Bacteroidetes,1IR29@117747|Sphingobacteriia	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	4.1.3.3,4.2.1.41,4.3.3.7	ko:K01639,ko:K01707,ko:K01714	ko00053,ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00053,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01811,R02279,R10147	RC00159,RC00600,RC00678,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YHH3_k127_4190315_1	1403819.BATR01000114_gene3892	5.598e-76	263.0	COG1053@1|root,COG1649@1|root,COG2755@1|root,COG4409@1|root,COG1053@2|Bacteria,COG1649@2|Bacteria,COG2755@2|Bacteria,COG4409@2|Bacteria,46UXH@74201|Verrucomicrobia,2ITNS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
YHH3_k127_4208124_3	1235800.C819_01018	8.979e-29	121.0	COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,24MPJ@186801|Clostridia,27QKZ@186928|unclassified Lachnospiraceae	186801|Clostridia	G	RbsD / FucU transport protein family	rbsD	-	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
YHH3_k127_4208124_4	1121012.AUKX01000036_gene788	4.705e-08	55.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,4NEQA@976|Bacteroidetes,1HZ5J@117743|Flavobacteriia,23FR6@178469|Arenibacter	976|Bacteroidetes	CEG	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,HEAT_2,Lipase_GDSL_2
YHH3_k127_4208124_1	1121918.ARWE01000001_gene746	1.261e-124	422.0	COG0457@1|root,COG0457@2|Bacteria,1R1JQ@1224|Proteobacteria,4377S@68525|delta/epsilon subdivisions,2WTFW@28221|Deltaproteobacteria,43U9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
YHH3_k127_4208124_5	706587.Desti_3767	1.614e-07	58.0	2CH0Y@1|root,3309M@2|Bacteria,1NF9M@1224|Proteobacteria,42VBP@68525|delta/epsilon subdivisions,2WRWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4208124_0	663610.JQKO01000001_gene926	7.906e-239	752.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria,3NAVK@45404|Beijerinckiaceae	28211|Alphaproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
YHH3_k127_4208124_6	395493.BegalDRAFT_2236	2.72e-05	48.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_42208_1	1125863.JAFN01000001_gene2867	1.358e-22	98.0	COG3335@1|root,COG3335@2|Bacteria,1MW8A@1224|Proteobacteria,42RGI@68525|delta/epsilon subdivisions,2WNGP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_29,HTH_33
YHH3_k127_42208_2	459349.CLOAM0680	3.443e-21	95.0	COG0236@1|root,COG0236@2|Bacteria,2NRZB@2323|unclassified Bacteria	2|Bacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
YHH3_k127_42208_0	880073.Calab_0579	1.531e-104	353.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	MA20_06645	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
YHH3_k127_42208_3	1121285.AUFK01000014_gene2708	1.117e-06	52.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia,3ZPBB@59732|Chryseobacterium	976|Bacteroidetes	IQ	3-ketoacyl-ACP reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH3_k127_4245719_0	56107.Cylst_2429	8.817e-25	109.0	COG3209@1|root,COG3209@2|Bacteria,1GQ3W@1117|Cyanobacteria,1HUCF@1161|Nostocales	1117|Cyanobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114
YHH3_k127_4245719_1	1123278.KB893587_gene555	4.349e-18	97.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47KK7@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
YHH3_k127_4245719_2	1006006.Mcup_1526	1.546e-06	54.0	COG0221@1|root,arCOG01711@2157|Archaea,2XQB5@28889|Crenarchaeota	28889|Crenarchaeota	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
YHH3_k127_4269588_1	1266909.AUAG01000032_gene2389	6.888e-29	117.0	COG3703@1|root,COG3703@2|Bacteria,1PJ04@1224|Proteobacteria,1S2RZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	AIG2-like family	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2
YHH3_k127_4269588_0	865937.Gilli_0826	1.463e-245	777.0	COG3511@1|root,COG3511@2|Bacteria,4NNZX@976|Bacteroidetes,1I5X5@117743|Flavobacteriia	976|Bacteroidetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
YHH3_k127_4273224_4	177439.DP1922	8.242e-41	153.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,42QRV@68525|delta/epsilon subdivisions,2WMUE@28221|Deltaproteobacteria,2MJY2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YHH3_k127_4273224_3	344747.PM8797T_17232	2.839e-42	166.0	COG1409@1|root,COG1409@2|Bacteria,2J37E@203682|Planctomycetes	203682|Planctomycetes	S	Pfam:DUF303	-	-	-	-	-	-	-	-	-	-	-	-	SASA
YHH3_k127_4273224_2	344747.PM8797T_25866	3.512e-153	507.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_4273224_0	545695.TREAZ_0999	4.251e-195	620.0	COG1486@1|root,COG1486@2|Bacteria,2J6Z5@203691|Spirochaetes	203691|Spirochaetes	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
YHH3_k127_4273224_1	583355.Caka_0971	9.666e-164	540.0	COG3525@1|root,COG3525@2|Bacteria,46UX5@74201|Verrucomicrobia,3K8TM@414999|Opitutae	414999|Opitutae	G	Glycosyl hydrolase, family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4274485_2	396588.Tgr7_2364	4.802e-56	203.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RXH3@1236|Gammaproteobacteria,1X18V@135613|Chromatiales	135613|Chromatiales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_4274485_1	396588.Tgr7_2363	2.82e-81	287.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,1RPTR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	exoQ	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH3_k127_4274485_0	448385.sce5832	7.709e-102	347.0	COG3866@1|root,COG3866@2|Bacteria,1MUT3@1224|Proteobacteria,42S47@68525|delta/epsilon subdivisions,2WND1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
YHH3_k127_4274485_3	396588.Tgr7_2350	7.953e-29	121.0	COG5434@1|root,COG5434@2|Bacteria,1RJPM@1224|Proteobacteria	1224|Proteobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH3_k127_4278157_5	1131462.DCF50_p2370	4.097e-20	91.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,26246@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
YHH3_k127_4278157_3	278957.ABEA03000097_gene773	2.459e-49	185.0	COG0546@1|root,COG0546@2|Bacteria,46VW7@74201|Verrucomicrobia,3K7X3@414999|Opitutae	414999|Opitutae	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH3_k127_4278157_0	794903.OPIT5_18610	8.435e-242	769.0	COG0507@1|root,COG0507@2|Bacteria,46U9H@74201|Verrucomicrobia,3K7J4@414999|Opitutae	414999|Opitutae	L	AAA ATPase	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
YHH3_k127_4278157_1	1223410.KN050846_gene1427	7.037e-142	463.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1HY0T@117743|Flavobacteriia	976|Bacteroidetes	F	nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
YHH3_k127_4278157_2	497964.CfE428DRAFT_1462	2.663e-60	218.0	COG0084@1|root,COG0084@2|Bacteria,46SRB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM TatD-related deoxyribonuclease	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YHH3_k127_4278157_4	583355.Caka_2501	5.93e-47	173.0	COG2166@1|root,COG2166@2|Bacteria,46W04@74201|Verrucomicrobia,3K88I@414999|Opitutae	414999|Opitutae	S	Fe-S metabolism	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
YHH3_k127_4314206_3	765952.PUV_07600	5.09e-19	88.0	COG1176@1|root,COG1176@2|Bacteria,2JG99@204428|Chlamydiae	204428|Chlamydiae	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
YHH3_k127_4314206_2	765952.PUV_07590	1.476e-79	276.0	COG1177@1|root,COG1177@2|Bacteria,2JFN9@204428|Chlamydiae	204428|Chlamydiae	P	Binding-protein-dependent transport system inner membrane component	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
YHH3_k127_4314206_1	1444711.CCJF01000005_gene1486	2.895e-100	338.0	COG0687@1|root,COG0687@2|Bacteria,2JGD6@204428|Chlamydiae	204428|Chlamydiae	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
YHH3_k127_4314206_0	382464.ABSI01000013_gene1635	4.365e-112	366.0	COG0667@1|root,COG0667@2|Bacteria,46UF5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_4328689_0	583355.Caka_1322	3.896e-109	358.0	COG0190@1|root,COG0190@2|Bacteria,46TG7@74201|Verrucomicrobia,3K7QM@414999|Opitutae	414999|Opitutae	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
YHH3_k127_4328689_1	583355.Caka_1324	4.14e-86	297.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,46UE8@74201|Verrucomicrobia,3K7D3@414999|Opitutae	414999|Opitutae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
YHH3_k127_4328689_2	583355.Caka_1325	6.944e-09	59.0	COG0345@1|root,COG0345@2|Bacteria,46T4K@74201|Verrucomicrobia,3K7QH@414999|Opitutae	414999|Opitutae	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
YHH3_k127_4365262_1	583355.Caka_0163	2.11e-65	233.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia,3K7UB@414999|Opitutae	414999|Opitutae	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
YHH3_k127_4365262_0	583355.Caka_0164	2.435e-102	340.0	COG0002@1|root,COG0002@2|Bacteria,46TRN@74201|Verrucomicrobia,3K8FU@414999|Opitutae	414999|Opitutae	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YHH3_k127_4393876_2	1121406.JAEX01000019_gene2763	2.667e-74	252.0	COG2086@1|root,COG2086@2|Bacteria,1R7VY@1224|Proteobacteria,42N0T@68525|delta/epsilon subdivisions,2WKSK@28221|Deltaproteobacteria,2M8V1@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
YHH3_k127_4393876_1	1121459.AQXE01000012_gene2279	1.922e-279	871.0	COG0644@1|root,COG1145@1|root,COG0644@2|Bacteria,COG1145@2|Bacteria,1MVU6@1224|Proteobacteria,42PTE@68525|delta/epsilon subdivisions,2WKRZ@28221|Deltaproteobacteria,2MA78@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein-ubiquinone	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
YHH3_k127_4393876_0	1121459.AQXE01000012_gene2280	9.901e-301	936.0	COG1960@1|root,COG1960@2|Bacteria,1PZ0R@1224|Proteobacteria,43E91@68525|delta/epsilon subdivisions,2X018@28221|Deltaproteobacteria,2M9QP@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
YHH3_k127_4393876_3	1121459.AQXE01000001_gene2584	3.161e-07	54.0	COG4783@1|root,COG4783@2|Bacteria,1QQVH@1224|Proteobacteria,42TUG@68525|delta/epsilon subdivisions,2WQFF@28221|Deltaproteobacteria,2MF80@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH3_k127_4402265_0	411476.BACOVA_03333	5.399e-90	310.0	COG3250@1|root,COG3250@2|Bacteria,4NFPC@976|Bacteroidetes,2FPUZ@200643|Bacteroidia,4AMTG@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_4402265_1	452637.Oter_3509	1.227e-75	270.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_4402265_2	382464.ABSI01000013_gene1717	1.845e-54	198.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,2IVCR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_440860_16	3712.Bo3g127600.1	2.535e-07	56.0	2E4EA@1|root,2S5QZ@2759|Eukaryota,38A44@33090|Viridiplantae,3GWQ7@35493|Streptophyta,3I1HA@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_440860_14	1123239.KB898627_gene3297	9.4e-14	74.0	2DSQW@1|root,33H3S@2|Bacteria,1VP4J@1239|Firmicutes,4HSVH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_440860_9	583355.Caka_1800	1.569e-46	172.0	COG2042@1|root,COG2042@2|Bacteria	2|Bacteria	S	rRNA processing	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	DTW,Ribo_biogen_C
YHH3_k127_440860_6	794903.OPIT5_01490	7.394e-59	211.0	COG0283@1|root,COG0283@2|Bacteria,46V54@74201|Verrucomicrobia,3K7W8@414999|Opitutae	414999|Opitutae	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
YHH3_k127_440860_2	583355.Caka_2286	1.718e-126	419.0	COG0128@1|root,COG0128@2|Bacteria,46TZ7@74201|Verrucomicrobia,3K8ZX@414999|Opitutae	414999|Opitutae	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
YHH3_k127_440860_3	583355.Caka_2287	2.679e-91	308.0	COG0287@1|root,COG0287@2|Bacteria,46URU@74201|Verrucomicrobia,3K7XP@414999|Opitutae	414999|Opitutae	E	Prephenate dehydrogenase	-	-	1.3.1.12,1.3.1.43	ko:K00220	ko00400,ko00401,ko01100,ko01110,ko01230,map00400,map00401,map01100,map01110,map01230	M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
YHH3_k127_440860_12	794903.OPIT5_28195	1.659e-33	148.0	COG1262@1|root,COG1262@2|Bacteria,46W2M@74201|Verrucomicrobia,3K81K@414999|Opitutae	414999|Opitutae	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
YHH3_k127_440860_13	452637.Oter_0825	1.489e-21	100.0	2E78G@1|root,313PD@2|Bacteria,46WXY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF3016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3016
YHH3_k127_440860_8	1382358.JHVN01000038_gene3215	6.866e-50	184.0	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli	91061|Bacilli	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	ydaF	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
YHH3_k127_440860_0	452637.Oter_0897	2.098e-205	660.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,46S6T@74201|Verrucomicrobia,3K7S6@414999|Opitutae	414999|Opitutae	CO	Disulphide bond corrector protein DsbC	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YHH3_k127_440860_15	555779.Dthio_PD1159	4.917e-11	68.0	COG0664@1|root,COG0664@2|Bacteria,1QZ42@1224|Proteobacteria,42XK7@68525|delta/epsilon subdivisions,2WSIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
YHH3_k127_440860_11	497964.CfE428DRAFT_2569	2.748e-38	150.0	COG1225@1|root,COG1225@2|Bacteria,46VGB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YHH3_k127_440860_18	292.DM42_5266	0.0001191	50.0	COG0526@1|root,COG0526@2|Bacteria,1MWU8@1224|Proteobacteria,2VPNK@28216|Betaproteobacteria,1K2PC@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
YHH3_k127_440860_17	551789.ATVJ01000003_gene235	2.774e-06	52.0	COG0683@1|root,COG0683@2|Bacteria,1NQNR@1224|Proteobacteria,2UPVS@28211|Alphaproteobacteria,43WZ0@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_440860_5	65393.PCC7424_1191	4.172e-86	300.0	COG0683@1|root,COG0683@2|Bacteria,1GBP3@1117|Cyanobacteria	1117|Cyanobacteria	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_440860_1	583355.Caka_1054	2.601e-136	447.0	COG2262@1|root,COG2262@2|Bacteria,46SP4@74201|Verrucomicrobia,3K7S8@414999|Opitutae	414999|Opitutae	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YHH3_k127_440860_4	1123020.AUIE01000003_gene708	1.584e-90	314.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1YIMI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH3_k127_440860_10	382464.ABSI01000011_gene2595	1.734e-46	184.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	phoQ	-	2.7.13.3	ko:K07637,ko:K07638,ko:K07717	ko01503,ko02020,ko02026,map01503,map02020,map02026	M00444,M00445,M00518,M00709,M00721,M00723,M00724,M00742,M00743,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HATPase_c_3,HisKA
YHH3_k127_440860_7	382464.ABSI01000011_gene2594	2.757e-55	215.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia,2IWIN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
YHH3_k127_4418122_2	1321781.HMPREF1985_00296	3.626e-07	54.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YHH3_k127_4418122_0	1313172.YM304_23690	2.32e-183	585.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CMWP@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
YHH3_k127_4418122_1	243275.TDE_0687	3.992e-53	192.0	COG0041@1|root,COG0041@2|Bacteria,2J96B@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YHH3_k127_4424693_1	666686.B1NLA3E_21100	0.000722	51.0	COG4655@1|root,COG4655@2|Bacteria,1V25X@1239|Firmicutes,4ITZ4@91061|Bacilli,1ZIQ4@1386|Bacillus	91061|Bacilli	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
YHH3_k127_4424693_0	1267535.KB906767_gene1382	3.489e-08	61.0	COG4961@1|root,COG4961@2|Bacteria,3Y95G@57723|Acidobacteria	57723|Acidobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
YHH3_k127_4451996_1	382464.ABSI01000011_gene2647	4.633e-65	224.0	COG0202@1|root,COG0202@2|Bacteria,46S52@74201|Verrucomicrobia,2ITN6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YHH3_k127_4451996_2	382464.ABSI01000011_gene2646	2.071e-47	176.0	COG0203@1|root,COG0203@2|Bacteria,46TC9@74201|Verrucomicrobia,2IUE5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
YHH3_k127_4451996_3	278957.ABEA03000152_gene4081	1.722e-10	64.0	29TM9@1|root,30EUT@2|Bacteria,46XC0@74201|Verrucomicrobia,3K8GF@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4451996_0	452637.Oter_0192	2.566e-176	560.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	414999|Opitutae	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
YHH3_k127_4453881_0	1121904.ARBP01000005_gene4483	2.744e-80	274.0	COG2010@1|root,COG2010@2|Bacteria,4NEJ0@976|Bacteroidetes,47NVV@768503|Cytophagia	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,PA14
YHH3_k127_4453881_2	583355.Caka_0492	1.703e-39	162.0	COG2273@1|root,COG3055@1|root,COG3291@1|root,COG3401@1|root,COG4932@1|root,COG5492@1|root,COG2273@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG3401@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,46UXF@74201|Verrucomicrobia,3K8Z6@414999|Opitutae	414999|Opitutae	N	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
YHH3_k127_4453881_1	243090.RB4017	9.659e-44	162.0	COG3119@1|root,COG3119@2|Bacteria,2IXG7@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_4459055_3	945713.IALB_2228	3.301e-104	350.0	COG0471@1|root,COG0471@2|Bacteria	2|Bacteria	P	metal ion transport	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
YHH3_k127_4459055_2	794903.OPIT5_18070	3.649e-114	389.0	COG0405@1|root,COG0405@2|Bacteria,46SGY@74201|Verrucomicrobia,3K9NS@414999|Opitutae	2|Bacteria	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YHH3_k127_4459055_4	382464.ABSI01000013_gene1580	4.006e-94	314.0	COG1802@1|root,COG1802@2|Bacteria,46Z79@74201|Verrucomicrobia,2IWQH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
YHH3_k127_4459055_0	382464.ABSI01000013_gene1579	0.0	1119.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH3_k127_4459055_1	382464.ABSI01000013_gene1578	5.904e-145	470.0	COG0624@1|root,COG0624@2|Bacteria,46VZE@74201|Verrucomicrobia,2IW3Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YHH3_k127_4459055_5	382464.ABSI01000013_gene1577	2.672e-80	283.0	COG3509@1|root,COG3509@2|Bacteria,46X2M@74201|Verrucomicrobia,2IW7R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4459055_6	382464.ABSI01000013_gene1576	3.262e-30	135.0	COG3069@1|root,COG3069@2|Bacteria	2|Bacteria	C	C4-dicarboxylate transmembrane transporter activity	-	-	-	ko:K03326	-	-	-	-	ko00000,ko02000	2.A.61.1	-	-	DcuC
YHH3_k127_4488453_1	313628.LNTAR_11951	5.631e-136	451.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_4488453_0	1121904.ARBP01000011_gene1486	1.278e-157	509.0	COG0673@1|root,COG0673@2|Bacteria,4NGPP@976|Bacteroidetes,47N04@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
YHH3_k127_4488453_3	452637.Oter_0060	1.355e-94	321.0	2DKW5@1|root,30J7Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4488453_2	1142394.PSMK_10370	1.921e-104	357.0	COG2755@1|root,COG3291@1|root,COG2755@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	wcoB	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	Lipase_GDSL_2
YHH3_k127_4489723_1	1121904.ARBP01000009_gene4313	5.134e-40	159.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4489723_0	314285.KT71_06272	3.56e-95	328.0	COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,1RZDP@1236|Gammaproteobacteria,1J9C0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH3_k127_4489723_2	161528.ED21_20779	8.195e-29	124.0	2FGC9@1|root,3488G@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
YHH3_k127_4526969_2	103733.JNYO01000037_gene4063	8.642e-06	52.0	COG1061@1|root,COG1061@2|Bacteria,2GM8Z@201174|Actinobacteria,4E221@85010|Pseudonocardiales	201174|Actinobacteria	KL	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C
YHH3_k127_4526969_0	2045.KR76_00100	5.128e-137	460.0	28HBW@1|root,2Z7NV@2|Bacteria,2GYFY@201174|Actinobacteria,4DR5G@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1998
YHH3_k127_4526969_1	1172188.KB911833_gene3908	1.066e-67	244.0	COG3973@1|root,COG3973@2|Bacteria,2IBE3@201174|Actinobacteria	201174|Actinobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,AAA_30,UvrD_C_2
YHH3_k127_4546687_0	882082.SaccyDRAFT_4473	2.232e-46	176.0	COG0491@1|root,COG0491@2|Bacteria,2GN7R@201174|Actinobacteria,4E1FN@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH3_k127_4546687_1	1217712.F971_00779	4.217e-06	51.0	COG0491@1|root,COG0491@2|Bacteria,1N1ZW@1224|Proteobacteria,1SGRF@1236|Gammaproteobacteria,3NK5U@468|Moraxellaceae	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH3_k127_4602664_2	382464.ABSI01000014_gene1484	1.847e-124	404.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,2IUGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347,HlyD_D23
YHH3_k127_4602664_0	382464.ABSI01000014_gene1483	4.689e-150	486.0	COG1538@1|root,COG1538@2|Bacteria,46WHQ@74201|Verrucomicrobia,2IW13@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_4602664_6	382464.ABSI01000014_gene1473	1.534e-52	191.0	COG1595@1|root,COG1595@2|Bacteria,46VX2@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_4602664_8	382464.ABSI01000011_gene2359	3.338e-33	133.0	COG3678@1|root,COG3678@2|Bacteria,46WX9@74201|Verrucomicrobia	2|Bacteria	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
YHH3_k127_4602664_3	583355.Caka_2760	6.096e-78	271.0	COG0470@1|root,COG0470@2|Bacteria,46T6T@74201|Verrucomicrobia,3K7VJ@414999|Opitutae	414999|Opitutae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
YHH3_k127_4602664_4	382464.ABSI01000005_gene1252	5.057e-75	257.0	COG0125@1|root,COG0125@2|Bacteria,46YZ4@74201|Verrucomicrobia,2IUD6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
YHH3_k127_4602664_1	382464.ABSI01000005_gene1253	6.823e-135	439.0	COG0524@1|root,COG0524@2|Bacteria,46TT7@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH3_k127_4602664_5	583355.Caka_2763	6.085e-67	234.0	COG0811@1|root,COG0811@2|Bacteria,46V1A@74201|Verrucomicrobia,3K7TP@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
YHH3_k127_4602664_7	583355.Caka_2764	1.053e-38	149.0	COG0848@1|root,COG0848@2|Bacteria,46T4F@74201|Verrucomicrobia,3K8EU@414999|Opitutae	414999|Opitutae	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH3_k127_4602664_11	1168059.KB899087_gene2167	1.174e-05	56.0	COG0810@1|root,COG0810@2|Bacteria,1MZXC@1224|Proteobacteria,2UCBT@28211|Alphaproteobacteria,3EZI3@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
YHH3_k127_4615861_0	452637.Oter_2241	2.723e-211	676.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	DUF1863,PQQ,PQQ_2,PQQ_3
YHH3_k127_4640233_1	583355.Caka_2233	3.638e-40	153.0	COG0414@1|root,COG0414@2|Bacteria,46SRN@74201|Verrucomicrobia,3K7TI@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
YHH3_k127_4640233_0	382464.ABSI01000011_gene2701	9.618e-201	632.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia,2ITKU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH3_k127_465245_4	583355.Caka_2004	2.557e-16	82.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
YHH3_k127_465245_0	583355.Caka_1978	7.82e-174	552.0	COG0505@1|root,COG0505@2|Bacteria,46TDX@74201|Verrucomicrobia,3K72S@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
YHH3_k127_465245_1	583355.Caka_2804	9.57e-154	491.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,3K7JX@414999|Opitutae	414999|Opitutae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
YHH3_k127_465245_6	237368.SCABRO_01502	6.734e-07	63.0	COG3307@1|root,COG3307@2|Bacteria,2J0S2@203682|Planctomycetes	203682|Planctomycetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH3_k127_465245_2	517418.Ctha_0694	3.422e-137	444.0	COG0714@1|root,COG0714@2|Bacteria,1FDTI@1090|Chlorobi	1090|Chlorobi	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YHH3_k127_465245_3	880073.Calab_2467	5.624e-97	326.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
YHH3_k127_465245_5	926551.KB900726_gene1894	3.487e-08	59.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1HY3G@117743|Flavobacteriia,1EQSU@1016|Capnocytophaga	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4661915_0	452637.Oter_3986	1.073e-187	591.0	COG0451@1|root,COG0451@2|Bacteria,46TDU@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
YHH3_k127_4661915_1	67257.JODR01000022_gene4931	8.989e-30	131.0	2EY4Y@1|root,33RDS@2|Bacteria,2GXMA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4663070_2	583355.Caka_0797	3.473e-23	100.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	gcdC	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
YHH3_k127_4663070_1	583355.Caka_0796	1.53e-155	499.0	COG1883@1|root,COG1883@2|Bacteria,46UVX@74201|Verrucomicrobia,3K7B0@414999|Opitutae	414999|Opitutae	C	TIGRFAM sodium ion-translocating decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
YHH3_k127_4663070_0	443144.GM21_3757	1.145e-284	901.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YHH3_k127_4693217_1	313612.L8106_17742	2.33e-73	265.0	COG5360@1|root,COG5360@2|Bacteria,1G4V0@1117|Cyanobacteria	1117|Cyanobacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
YHH3_k127_4693217_0	452637.Oter_3096	2.745e-139	451.0	COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,3K7BN@414999|Opitutae	414999|Opitutae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YHH3_k127_4700652_2	1195236.CTER_4237	2.744e-145	482.0	COG3250@1|root,COG3250@2|Bacteria,1VSYK@1239|Firmicutes,24D78@186801|Clostridia,3WSA4@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C
YHH3_k127_4700652_6	756272.Plabr_3627	1.348e-116	389.0	COG2133@1|root,COG2133@2|Bacteria,2IZH6@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH3_k127_4700652_3	756272.Plabr_2754	7.573e-139	448.0	COG1082@1|root,COG1082@2|Bacteria,2IY10@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_4700652_8	1123070.KB899255_gene1391	2.818e-50	188.0	COG2207@1|root,COG2207@2|Bacteria,46STY@74201|Verrucomicrobia,2IVPP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PAS_4
YHH3_k127_4700652_1	595460.RRSWK_01727	1.537e-182	577.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_4700652_0	471854.Dfer_3169	9.195e-216	674.0	COG1482@1|root,COG1482@2|Bacteria,4NGGP@976|Bacteroidetes,47NZ6@768503|Cytophagia	976|Bacteroidetes	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4700652_5	344747.PM8797T_11556	8.006e-133	437.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_4700652_4	344747.PM8797T_11556	3.281e-133	438.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_4700652_7	313628.LNTAR_17148	3.933e-51	192.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,HEAT_2,NPCBM,ThuA
YHH3_k127_4704621_0	452637.Oter_3293	1.811e-197	628.0	COG0281@1|root,COG0281@2|Bacteria,46UI4@74201|Verrucomicrobia,3K7KY@414999|Opitutae	414999|Opitutae	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
YHH3_k127_4719721_6	1499685.CCFJ01000046_gene3047	0.0001025	46.0	2AWWS@1|root,31NUA@2|Bacteria,1TZQC@1239|Firmicutes,4II4H@91061|Bacilli,1ZKNB@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4719721_0	1267580.AF6_2521	1.46e-47	177.0	COG4974@1|root,COG4974@2|Bacteria,1UCSJ@1239|Firmicutes,4HIBV@91061|Bacilli	91061|Bacilli	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
YHH3_k127_4719721_2	713587.THITH_04690	1.678e-21	96.0	COG2929@1|root,COG2929@2|Bacteria,1N3AZ@1224|Proteobacteria,1SQ13@1236|Gammaproteobacteria,1X189@135613|Chromatiales	135613|Chromatiales	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH3_k127_4719721_3	1028801.RG1141_CH20340	1.922e-18	89.0	COG3620@1|root,COG3620@2|Bacteria,1PUPC@1224|Proteobacteria,2V2K5@28211|Alphaproteobacteria,4BK64@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH3_k127_4719721_1	1244869.H261_19039	1.093e-32	129.0	COG4679@1|root,COG4679@2|Bacteria,1MZ3N@1224|Proteobacteria,2UBYT@28211|Alphaproteobacteria,2JTPN@204441|Rhodospirillales	204441|Rhodospirillales	S	COG4679 Phage-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
YHH3_k127_4719721_4	1408311.JNJM01000027_gene2781	3.301e-10	65.0	COG1569@1|root,COG1569@2|Bacteria,1VHAV@1239|Firmicutes,24QPU@186801|Clostridia,2PTBZ@265975|Oribacterium	186801|Clostridia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH3_k127_4729035_1	504487.JCM19302_2061	2.599e-19	103.0	COG3664@1|root,COG3664@2|Bacteria,4NHQ0@976|Bacteroidetes,1I5WJ@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_39
YHH3_k127_4729035_0	886293.Sinac_7118	1.649e-35	142.0	COG3119@1|root,COG3119@2|Bacteria,2IXIE@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
YHH3_k127_4738472_5	518766.Rmar_0276	5.001e-70	244.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1FJ6W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Eukaryotic integral membrane protein (DUF1751)	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
YHH3_k127_4738472_7	583355.Caka_1952	7.586e-58	203.0	COG4508@1|root,COG4508@2|Bacteria,46VH7@74201|Verrucomicrobia,3K7ZP@414999|Opitutae	414999|Opitutae	S	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
YHH3_k127_4738472_0	583355.Caka_1954	7.721e-173	552.0	COG0766@1|root,COG0766@2|Bacteria,46U7P@74201|Verrucomicrobia,3K78X@414999|Opitutae	414999|Opitutae	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
YHH3_k127_4738472_2	794903.OPIT5_09820	3.54e-151	485.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia,3K7S9@414999|Opitutae	414999|Opitutae	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YHH3_k127_4738472_6	1038858.AXBA01000007_gene1079	3.92e-62	225.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,3EYZX@335928|Xanthobacteraceae	28211|Alphaproteobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	yejF	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
YHH3_k127_4738472_3	583355.Caka_0905	3.057e-73	254.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YHH3_k127_4738472_1	583355.Caka_1852	3.342e-164	529.0	COG1233@1|root,COG1233@2|Bacteria,46TRV@74201|Verrucomicrobia,3K78Y@414999|Opitutae	414999|Opitutae	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
YHH3_k127_4738472_8	794903.OPIT5_30050	2.519e-34	133.0	COG0236@1|root,COG0236@2|Bacteria,46W39@74201|Verrucomicrobia,3K88G@414999|Opitutae	414999|Opitutae	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
YHH3_k127_4738472_4	382464.ABSI01000023_gene607	3.032e-72	246.0	COG0304@1|root,COG0304@2|Bacteria,46SBU@74201|Verrucomicrobia,2ITS2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH3_k127_4746266_2	1246995.AFR_01255	2.292e-15	79.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4DAD5@85008|Micromonosporales	201174|Actinobacteria	E	Oligopeptidase b	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
YHH3_k127_4746266_0	278957.ABEA03000060_gene3150	3.656e-213	668.0	COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,3K78I@414999|Opitutae	414999|Opitutae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
YHH3_k127_4746266_1	583355.Caka_0946	3.189e-100	334.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,46S5K@74201|Verrucomicrobia,3K7D9@414999|Opitutae	414999|Opitutae	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
YHH3_k127_4751908_1	583355.Caka_0597	1.673e-66	239.0	COG0457@1|root,COG0457@2|Bacteria,46UPB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1,TPR_8
YHH3_k127_4751908_4	382245.ASA_3012	2.711e-38	148.0	COG3832@1|root,COG3832@2|Bacteria,1NKFS@1224|Proteobacteria	1224|Proteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YHH3_k127_4751908_2	583355.Caka_1303	3.923e-64	228.0	COG0564@1|root,COG0564@2|Bacteria,46V2B@74201|Verrucomicrobia,3K828@414999|Opitutae	414999|Opitutae	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
YHH3_k127_4751908_5	583355.Caka_1305	2.577e-33	132.0	COG1544@1|root,COG1544@2|Bacteria,46WAP@74201|Verrucomicrobia,3K89Z@414999|Opitutae	414999|Opitutae	J	PFAM sigma 54 modulation protein ribosomal protein S30EA	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
YHH3_k127_4751908_0	452637.Oter_0645	2.327e-70	269.0	COG2887@1|root,COG2887@2|Bacteria,46SDQ@74201|Verrucomicrobia,3K85H@414999|Opitutae	414999|Opitutae	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
YHH3_k127_4751908_3	452637.Oter_0644	2.678e-44	171.0	COG1074@1|root,COG1074@2|Bacteria,46SF0@74201|Verrucomicrobia,3K7V5@414999|Opitutae	414999|Opitutae	L	PD-(D/E)XK nuclease superfamily	-	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH3_k127_4764787_3	382464.ABSI01000005_gene1150	1.385e-57	203.0	COG2211@1|root,COG2211@2|Bacteria,46UNF@74201|Verrucomicrobia,2IV5Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
YHH3_k127_4764787_2	926569.ANT_28570	1.961e-136	445.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CBM_2,Dockerin_1,Glyco_hydro_8,Polysacc_deac_1
YHH3_k127_4764787_5	1123057.P872_10295	1.528e-23	104.0	COG5520@1|root,COG5520@2|Bacteria	2|Bacteria	M	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.136,3.2.1.55,3.2.1.8	ko:K01181,ko:K15921,ko:K15924	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43,GH5	-	Beta_helix,Binary_toxB_2,Binary_toxB_3,CBM_6,CW_binding_1,Dockerin_1,Glyco_hydro_10,Glyco_hydro_30,Glyco_hydro_30C,Glyco_hydro_43,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin
YHH3_k127_4764787_1	452637.Oter_4311	3.585e-142	462.0	COG1609@1|root,COG1609@2|Bacteria,46TVE@74201|Verrucomicrobia,3K935@414999|Opitutae	414999|Opitutae	K	PFAM regulatory protein LacI	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI
YHH3_k127_4764787_0	1396141.BATP01000001_gene5354	1.303e-257	802.0	COG3507@1|root,COG3507@2|Bacteria,46TG8@74201|Verrucomicrobia,2IVK1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
YHH3_k127_4764787_4	382464.ABSI01000009_gene3968	1.356e-32	128.0	COG1312@1|root,COG1312@2|Bacteria	2|Bacteria	G	mannonate dehydratase activity	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
YHH3_k127_4764787_6	29908.U7PNA1	4.019e-05	55.0	COG5184@1|root,KOG1426@2759|Eukaryota,39G0B@33154|Opisthokonta,3NVDB@4751|Fungi,3QMM5@4890|Ascomycota,213WD@147550|Sordariomycetes,3US6X@5151|Ophiostomatales	4751|Fungi	DZ	Regulator of chromosome condensation (RCC1) repeat	-	GO:0000054,GO:0000228,GO:0000785,GO:0000790,GO:0003674,GO:0005085,GO:0005087,GO:0005088,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005819,GO:0005856,GO:0006403,GO:0006405,GO:0006406,GO:0006407,GO:0006611,GO:0006810,GO:0006886,GO:0006913,GO:0007088,GO:0007096,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0007346,GO:0008104,GO:0008150,GO:0008152,GO:0008536,GO:0009987,GO:0010389,GO:0010467,GO:0010564,GO:0010948,GO:0010972,GO:0015031,GO:0015630,GO:0015833,GO:0015931,GO:0016020,GO:0016021,GO:0016973,GO:0017016,GO:0019899,GO:0022613,GO:0023052,GO:0031224,GO:0031267,GO:0031291,GO:0031503,GO:0031974,GO:0031981,GO:0032386,GO:0032388,GO:0032879,GO:0032880,GO:0032886,GO:0032887,GO:0032888,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0033157,GO:0033750,GO:0034613,GO:0035556,GO:0042254,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044428,GO:0044430,GO:0044446,GO:0044454,GO:0044464,GO:0045184,GO:0045786,GO:0045930,GO:0046822,GO:0046824,GO:0046825,GO:0046827,GO:0046907,GO:0048518,GO:0048519,GO:0048523,GO:0050657,GO:0050658,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051028,GO:0051029,GO:0051049,GO:0051050,GO:0051128,GO:0051168,GO:0051169,GO:0051179,GO:0051222,GO:0051223,GO:0051233,GO:0051234,GO:0051236,GO:0051493,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0051716,GO:0051726,GO:0051783,GO:0051983,GO:0060236,GO:0060341,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070507,GO:0070727,GO:0071166,GO:0071426,GO:0071427,GO:0071428,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072686,GO:0090087,GO:0090169,GO:0090224,GO:0090316,GO:0097064,GO:0098772,GO:1901673,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902115,GO:1902749,GO:1902750,GO:1903827,GO:1903829,GO:1904951,GO:1990023	-	ko:K11493	-	-	-	-	ko00000,ko03019,ko03036	-	-	-	RCC1,RCC1_2
YHH3_k127_4776634_0	1192034.CAP_0825	5.782e-94	327.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4776634_1	1235803.C825_05072	2.256e-08	63.0	2CK1R@1|root,32V4M@2|Bacteria,4NTYZ@976|Bacteroidetes,2FU5M@200643|Bacteroidia,22ZP3@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4788489_3	583355.Caka_2266	1.371e-65	235.0	COG0457@1|root,COG0457@2|Bacteria	583355.Caka_2266|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4788489_7	583355.Caka_2237	3.572e-22	104.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
YHH3_k127_4788489_4	382464.ABSI01000012_gene2056	3.633e-49	178.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH3_k127_4788489_5	382464.ABSI01000007_gene4062	1.118e-37	149.0	COG0811@1|root,COG0811@2|Bacteria,46VPT@74201|Verrucomicrobia,2IWJ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
YHH3_k127_4788489_2	382464.ABSI01000012_gene2058	3.461e-103	352.0	COG0811@1|root,COG0811@2|Bacteria,46UAW@74201|Verrucomicrobia,2IVTF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
YHH3_k127_4788489_6	382464.ABSI01000007_gene4064	1.053e-35	146.0	2E0WS@1|root,32WDT@2|Bacteria,46V9V@74201|Verrucomicrobia,2IWIE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
YHH3_k127_4788489_1	382464.ABSI01000002_gene4375	5.221e-135	435.0	COG2878@1|root,COG2878@2|Bacteria	2|Bacteria	C	electron transfer activity	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_7
YHH3_k127_4788489_0	382464.ABSI01000002_gene4374	0.0	1793.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH3_k127_4824763_5	4530.OS08T0557400-01	8.168e-49	180.0	COG0394@1|root,KOG3217@2759|Eukaryota,37NNM@33090|Viridiplantae,3GCJD@35493|Streptophyta,3KYMR@4447|Liliopsida,3IDH1@38820|Poales	35493|Streptophyta	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YHH3_k127_4824763_7	794903.OPIT5_28635	7.517e-46	175.0	COG1385@1|root,COG1385@2|Bacteria,46V87@74201|Verrucomicrobia,3K833@414999|Opitutae	414999|Opitutae	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
YHH3_k127_4824763_6	452637.Oter_0683	2.16e-47	176.0	COG0742@1|root,COG0742@2|Bacteria,46VKM@74201|Verrucomicrobia,3K8B1@414999|Opitutae	414999|Opitutae	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
YHH3_k127_4824763_3	452637.Oter_0684	1.481e-85	300.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6
YHH3_k127_4824763_4	452637.Oter_0685	5.783e-81	276.0	COG0767@1|root,COG0767@2|Bacteria,46ZIM@74201|Verrucomicrobia,3K7D7@414999|Opitutae	414999|Opitutae	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YHH3_k127_4824763_2	452637.Oter_0686	2.124e-89	302.0	COG1127@1|root,COG1127@2|Bacteria,46SRC@74201|Verrucomicrobia,3K7XJ@414999|Opitutae	414999|Opitutae	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YHH3_k127_4824763_8	1123371.ATXH01000005_gene2035	1.296e-43	171.0	COG1463@1|root,COG1463@2|Bacteria,2GGR8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
YHH3_k127_4824763_9	240016.ABIZ01000001_gene9	1.907e-34	143.0	COG1385@1|root,COG1385@2|Bacteria,46SZQ@74201|Verrucomicrobia,2IUB0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
YHH3_k127_4824763_0	278957.ABEA03000126_gene3724	1.934e-221	696.0	COG5016@1|root,COG5016@2|Bacteria,46TT6@74201|Verrucomicrobia,3K76D@414999|Opitutae	414999|Opitutae	C	Pyruvate carboxyltransferase	-	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
YHH3_k127_4824763_1	583355.Caka_1187	4.087e-99	332.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Guanylate_cyc,HAMP,Response_reg,dCache_1
YHH3_k127_4824763_10	278957.ABEA03000196_gene392	5.904e-11	68.0	28VFN@1|root,2ZHI7@2|Bacteria,46WGU@74201|Verrucomicrobia,3K8FV@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4844105_0	234267.Acid_4012	4.795e-156	509.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_487018_5	926549.KI421517_gene3318	8.768e-24	104.0	COG1482@1|root,COG1482@2|Bacteria,4NH8R@976|Bacteroidetes	976|Bacteroidetes	G	Phosphomannose isomerase type I	-	-	-	-	-	-	-	-	-	-	-	-	PMI_typeI
YHH3_k127_487018_0	344747.PM8797T_00157	1.189e-142	473.0	COG3119@1|root,COG3119@2|Bacteria,2J1S4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_487018_1	314230.DSM3645_17230	2.102e-113	382.0	COG3540@1|root,COG3540@2|Bacteria,2J1QH@203682|Planctomycetes	203682|Planctomycetes	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
YHH3_k127_487018_4	382464.ABSI01000010_gene3793	8.247e-60	213.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_487018_2	521674.Plim_0354	7.422e-106	370.0	COG3119@1|root,COG3119@2|Bacteria,2IWX1@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
YHH3_k127_487018_3	1121875.KB907549_gene1990	6.273e-65	247.0	COG1082@1|root,COG2152@1|root,COG1082@2|Bacteria,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,1HYH2@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_4873271_2	595460.RRSWK_02626	5.777e-44	166.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_4873271_0	595460.RRSWK_02020	4.326e-127	423.0	COG0673@1|root,COG0673@2|Bacteria,2IX5C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_4873271_1	595460.RRSWK_02020	2.178e-108	363.0	COG0673@1|root,COG0673@2|Bacteria,2IX5C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_4882659_2	1232410.KI421424_gene1760	2.477e-22	96.0	COG2010@1|root,COG2010@2|Bacteria,1QYFZ@1224|Proteobacteria,43CC3@68525|delta/epsilon subdivisions,2WQTQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4882659_1	404589.Anae109_2407	2.926e-125	409.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria,2YWQF@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
YHH3_k127_4882659_0	1121920.AUAU01000009_gene1860	2.356e-142	460.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
YHH3_k127_488519_0	56110.Oscil6304_1450	1.146e-16	93.0	2DBBA@1|root,2Z86Y@2|Bacteria,1G1AR@1117|Cyanobacteria,1H8WP@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4929542_0	760192.Halhy_3866	6.56e-38	164.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Beta_helix,Calx-beta,DUF4347,SLH,VCBS
YHH3_k127_4929542_1	1279009.ADICEAN_00691	8.663e-21	108.0	COG3210@1|root,COG3291@1|root,COG4733@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NDZC@976|Bacteroidetes,47SFQ@768503|Cytophagia	976|Bacteroidetes	O	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SASA,SprB
YHH3_k127_4946319_0	926569.ANT_16090	1.214e-45	170.0	COG0491@1|root,COG0491@2|Bacteria,2G6X9@200795|Chloroflexi	200795|Chloroflexi	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH3_k127_4946319_1	1296416.JACB01000029_gene4119	5.999e-05	55.0	COG5276@1|root,COG5276@2|Bacteria,4NPJY@976|Bacteroidetes,1I2K9@117743|Flavobacteriia,2YK88@290174|Aquimarina	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SusE,fn3
YHH3_k127_4948415_1	583355.Caka_2201	7.104e-74	259.0	COG3429@1|root,COG3429@2|Bacteria,46V1R@74201|Verrucomicrobia,3K72Y@414999|Opitutae	414999|Opitutae	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
YHH3_k127_4948415_0	583355.Caka_1958	7.382e-124	403.0	COG0162@1|root,COG0162@2|Bacteria,46UVG@74201|Verrucomicrobia,3K7IA@414999|Opitutae	414999|Opitutae	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
YHH3_k127_4948415_2	583355.Caka_1742	2.834e-40	155.0	2FADU@1|root,342N6@2|Bacteria,46VMD@74201|Verrucomicrobia,3K81H@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
YHH3_k127_4948415_3	1408424.JHYI01000018_gene3120	5.98e-25	108.0	COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,4HIP6@91061|Bacilli,1ZG7Z@1386|Bacillus	91061|Bacilli	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YHH3_k127_495382_11	794903.OPIT5_01645	1.72e-69	242.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia,3K793@414999|Opitutae	414999|Opitutae	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
YHH3_k127_495382_5	583355.Caka_1048	1.182e-99	344.0	COG0728@1|root,COG0728@2|Bacteria,46SH1@74201|Verrucomicrobia,3K78B@414999|Opitutae	414999|Opitutae	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YHH3_k127_495382_2	583355.Caka_1068	4.142e-117	381.0	COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia,3K75T@414999|Opitutae	414999|Opitutae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YHH3_k127_495382_0	583355.Caka_1067	5.161e-264	824.0	COG4289@1|root,COG4289@2|Bacteria,46UB4@74201|Verrucomicrobia,3K7DP@414999|Opitutae	414999|Opitutae	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_495382_4	78245.Xaut_1824	1.952e-106	357.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,3EYP5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
YHH3_k127_495382_12	436717.AOLE_17580	2.357e-05	53.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,3NN5T@468|Moraxellaceae	1236|Gammaproteobacteria	U	general secretion pathway protein	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
YHH3_k127_495382_10	1121403.AUCV01000043_gene105	1.431e-77	269.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,42S4J@68525|delta/epsilon subdivisions,2WNH4@28221|Deltaproteobacteria,2MKB8@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
YHH3_k127_495382_3	583355.Caka_1598	1.651e-111	366.0	COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia,3K7F5@414999|Opitutae	414999|Opitutae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
YHH3_k127_495382_1	1121472.AQWN01000011_gene1225	1.97e-256	822.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,26131@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh,Pro_dh
YHH3_k127_495382_9	857087.Metme_1196	2e-80	278.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,1XE47@135618|Methylococcales	135618|Methylococcales	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH3_k127_495382_8	580340.Tlie_1809	6.122e-84	305.0	COG0399@1|root,COG0399@2|Bacteria,3T9ZV@508458|Synergistetes	508458|Synergistetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH3_k127_495382_6	382464.ABSI01000011_gene3187	1.164e-95	334.0	COG0815@1|root,COG0815@2|Bacteria,46W4F@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the fatty acyl group on membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_495382_7	583355.Caka_0848	5.695e-90	307.0	COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia,3K7AR@414999|Opitutae	414999|Opitutae	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
YHH3_k127_4973889_3	583355.Caka_2810	5.276e-76	256.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia,3K7KT@414999|Opitutae	414999|Opitutae	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
YHH3_k127_4973889_6	583355.Caka_0752	2.93e-40	153.0	COG4747@1|root,COG4747@2|Bacteria,46SXP@74201|Verrucomicrobia,3K816@414999|Opitutae	414999|Opitutae	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4973889_4	583355.Caka_2122	5.189e-42	154.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,3K8AH@414999|Opitutae	414999|Opitutae	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
YHH3_k127_4973889_5	382464.ABSI01000002_gene4276	2.649e-41	164.0	COG0705@1|root,COG0705@2|Bacteria,46W15@74201|Verrucomicrobia,2IUFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH3_k127_4973889_0	452637.Oter_0871	1.768e-222	712.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
YHH3_k127_4973889_8	521674.Plim_2697	9.754e-15	76.0	COG1918@1|root,COG1918@2|Bacteria,2J0K6@203682|Planctomycetes	203682|Planctomycetes	P	COG1918 Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
YHH3_k127_4973889_1	1122176.KB903553_gene3659	1.932e-119	396.0	COG3934@1|root,COG3934@2|Bacteria,4PMNF@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
YHH3_k127_4973889_2	382464.ABSI01000011_gene2586	7.13e-104	348.0	COG1609@1|root,COG1609@2|Bacteria,46XF0@74201|Verrucomicrobia,2IVQK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3
YHH3_k127_4973889_7	452637.Oter_1266	1.077e-24	109.0	COG1609@1|root,COG1609@2|Bacteria,46TTK@74201|Verrucomicrobia,3K8QR@414999|Opitutae	414999|Opitutae	K	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
YHH3_k127_4978833_0	278957.ABEA03000176_gene2834	1.053e-41	158.0	28W7P@1|root,2ZI89@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4978833_2	1150600.ADIARSV_0331	3.079e-06	51.0	COG4849@1|root,COG4849@2|Bacteria,4NMEZ@976|Bacteroidetes,1ISGC@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH3_k127_4978833_1	1121456.ATVA01000017_gene166	9.985e-24	104.0	COG4849@1|root,COG4849@2|Bacteria,1RDHG@1224|Proteobacteria,42WAF@68525|delta/epsilon subdivisions,2WRPU@28221|Deltaproteobacteria,2M9UD@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4980911_1	583355.Caka_1959	2.816e-53	191.0	COG1225@1|root,COG1225@2|Bacteria,46V63@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YHH3_k127_4980911_0	497964.CfE428DRAFT_1607	0.0	1193.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH3_k127_4980911_2	382464.ABSI01000013_gene1905	5.777e-44	166.0	COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,2IURI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
YHH3_k127_4980911_3	382464.ABSI01000013_gene1906	2.581e-39	151.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,46SWK@74201|Verrucomicrobia,2ITX4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
YHH3_k127_4986041_0	641524.ADICYQ_3297	9.829e-93	311.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,47UAT@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_4986041_1	756272.Plabr_3776	6.488e-68	252.0	COG0657@1|root,COG0657@2|Bacteria,2IZ20@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
YHH3_k127_4991975_3	1403819.BATR01000022_gene806	3.537e-30	122.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
YHH3_k127_4991975_0	1288963.ADIS_1633	1.075e-74	263.0	COG4948@1|root,COG4948@2|Bacteria,4NKNN@976|Bacteroidetes,47JKW@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
YHH3_k127_4991975_2	240016.ABIZ01000001_gene5154	6.519e-52	204.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_4991975_1	1232437.KL662020_gene700	1.038e-72	268.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2MMGU@213118|Desulfobacterales	28221|Deltaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH3_k127_5017470_0	762984.HMPREF9445_00244	7.414e-161	535.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia,4AP3C@815|Bacteroidaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NPCBM
YHH3_k127_5017470_1	756272.Plabr_3205	5.574e-06	60.0	COG1520@1|root,COG1520@2|Bacteria,2IWVC@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YHH3_k127_5029643_3	768706.Desor_1479	2.043e-08	58.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,262AS@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.34	ko:K12508	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
YHH3_k127_5029643_1	1129794.C427_3684	3.648e-83	282.0	COG1028@1|root,COG1028@2|Bacteria,1PKAZ@1224|Proteobacteria,1S0A6@1236|Gammaproteobacteria,46A4M@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH3_k127_5029643_0	234831.PSM_A0447	5.239e-93	312.0	COG1043@1|root,COG1043@2|Bacteria,1R50P@1224|Proteobacteria,1S062@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YHH3_k127_5029643_2	1173029.JH980292_gene4143	3.03e-50	184.0	COG0110@1|root,COG0110@2|Bacteria,1G65X@1117|Cyanobacteria,1HG2I@1150|Oscillatoriales	1117|Cyanobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep
YHH3_k127_5031776_1	620914.JH621248_gene3199	2.974e-29	136.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	celA	-	2.4.1.12,3.2.1.4	ko:K00694,ko:K01179	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889,R06200,R11307,R11308	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GH5,GH9,GT2	-	CBM_2,Cellulase,Glycos_transf_2
YHH3_k127_5031776_0	1336803.PHEL49_1336	1.294e-100	357.0	COG3119@1|root,COG3119@2|Bacteria,4NUHG@976|Bacteroidetes,1I8JK@117743|Flavobacteriia,3VXCR@52959|Polaribacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_5031776_2	1123242.JH636435_gene1838	6.502e-27	119.0	COG1914@1|root,COG1914@2|Bacteria,2IWTS@203682|Planctomycetes	203682|Planctomycetes	P	COG1914 Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
YHH3_k127_5064470_3	452637.Oter_1787	1.886e-28	119.0	COG1929@1|root,COG1929@2|Bacteria,46TGW@74201|Verrucomicrobia,3K730@414999|Opitutae	414999|Opitutae	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
YHH3_k127_5064470_0	382464.ABSI01000006_gene946	1.794e-132	437.0	COG3540@1|root,COG3540@2|Bacteria,46VN0@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5064470_1	1396141.BATP01000029_gene2254	6.436e-83	284.0	COG1573@1|root,COG1573@2|Bacteria,46UE4@74201|Verrucomicrobia,2ITSY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	uracil-dna glycosylase	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH3_k127_5064470_2	583355.Caka_1731	4.873e-81	280.0	COG0772@1|root,COG0772@2|Bacteria,46SQT@74201|Verrucomicrobia,3K7H4@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
YHH3_k127_5071462_3	452637.Oter_2241	1.202e-10	65.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	DUF1863,PQQ,PQQ_2,PQQ_3
YHH3_k127_5071462_2	794903.OPIT5_09030	2.723e-12	79.0	COG0810@1|root,COG0810@2|Bacteria,46WRI@74201|Verrucomicrobia,3K8HB@414999|Opitutae	414999|Opitutae	M	Biopolymer transporter TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH3_k127_5071462_4	794903.OPIT5_05985	3.111e-08	57.0	COG0657@1|root,COG2730@1|root,COG0657@2|Bacteria,COG2730@2|Bacteria,46UXG@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DLH
YHH3_k127_5071462_0	794903.OPIT5_16195	1.092e-78	271.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
YHH3_k127_5071462_1	398767.Glov_0093	7.898e-75	261.0	COG3177@1|root,COG3177@2|Bacteria,1NB0K@1224|Proteobacteria,42QY1@68525|delta/epsilon subdivisions,2WMXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH3_k127_510145_3	497964.CfE428DRAFT_4797	1.124e-24	107.0	COG3866@1|root,COG3866@2|Bacteria,46SQX@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_510145_2	794903.OPIT5_20755	2.319e-84	303.0	28KZU@1|root,2ZAF0@2|Bacteria,46TCQ@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Polysaccharide lyase family 4, domain III	-	-	4.2.2.23	ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,Rhamnogal_lyase,fn3_3
YHH3_k127_510145_0	344747.PM8797T_04335	3.802e-164	531.0	COG3119@1|root,COG3119@2|Bacteria,2J2Z5@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
YHH3_k127_510145_1	595460.RRSWK_06163	4.202e-138	458.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
YHH3_k127_510145_4	1396418.BATQ01000016_gene4259	1.329e-10	64.0	COG3119@1|root,COG3119@2|Bacteria,46UXB@74201|Verrucomicrobia,2IV6X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_5113126_2	765912.Thimo_0664	9.599e-83	282.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
YHH3_k127_5113126_0	926550.CLDAP_06140	3.256e-144	463.0	COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH3_k127_5113126_1	28229.ND2E_4140	4.897e-83	279.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,1RMDK@1236|Gammaproteobacteria,2Q63J@267889|Colwelliaceae	1236|Gammaproteobacteria	C	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0842,iYL1228.KPN_00772	GalP_UDP_tr_C,GalP_UDP_transf
YHH3_k127_5135474_5	1274524.BSONL12_19389	5.582e-11	63.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,1ZBUI@1386|Bacillus	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YHH3_k127_5135474_1	583355.Caka_1276	1.335e-100	338.0	COG0673@1|root,COG0673@2|Bacteria,46TQ2@74201|Verrucomicrobia,3K940@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_5135474_3	583355.Caka_1613	1.222e-68	237.0	COG0634@1|root,COG0634@2|Bacteria,46T02@74201|Verrucomicrobia,3K7XB@414999|Opitutae	414999|Opitutae	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
YHH3_k127_5135474_4	583355.Caka_1278	4.168e-57	211.0	COG1136@1|root,COG1136@2|Bacteria,46V18@74201|Verrucomicrobia,3K79A@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
YHH3_k127_5135474_2	452637.Oter_2084	1.315e-91	316.0	COG4591@1|root,COG4591@2|Bacteria,46SKZ@74201|Verrucomicrobia,3K74K@414999|Opitutae	414999|Opitutae	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
YHH3_k127_5135474_0	794903.OPIT5_14640	9.676e-204	644.0	COG1190@1|root,COG1190@2|Bacteria,46TIA@74201|Verrucomicrobia,3K7FJ@414999|Opitutae	414999|Opitutae	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YHH3_k127_5135474_6	497964.CfE428DRAFT_6408	2.69e-10	71.0	COG3210@1|root,COG5306@1|root,COG3210@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	U	domain, Protein	exbB2	-	-	ko:K03561,ko:K12287	-	-	-	-	ko00000,ko02000,ko02044	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,MotA_ExbB
YHH3_k127_5136393_8	452637.Oter_3164	4.576e-24	103.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
YHH3_k127_5136393_3	880073.Calab_3082	1.63e-120	407.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	celD	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calycin_like,CelD_N,Glyco_hydro_9,PCMD
YHH3_k127_5136393_1	701176.VIBRN418_17608	5.992e-206	657.0	COG0726@1|root,COG0726@2|Bacteria,1QXDY@1224|Proteobacteria,1T39I@1236|Gammaproteobacteria,1Y34J@135623|Vibrionales	135623|Vibrionales	G	Cellulase N-terminal ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
YHH3_k127_5136393_6	243233.MCA3072	7.721e-97	323.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1XE1F@135618|Methylococcales	135618|Methylococcales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
YHH3_k127_5136393_5	1124780.ANNU01000032_gene1222	8.41e-109	368.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,47XKT@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
YHH3_k127_5136393_2	1124780.ANNU01000032_gene1223	6.625e-125	411.0	COG0845@1|root,COG0845@2|Bacteria,4NF0X@976|Bacteroidetes,47U0H@768503|Cytophagia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
YHH3_k127_5136393_0	1168289.AJKI01000031_gene931	0.0	1409.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_5136393_4	545694.TREPR_1612	3.592e-116	383.0	COG2152@1|root,COG2152@2|Bacteria,2J65K@203691|Spirochaetes	203691|Spirochaetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
YHH3_k127_5136393_10	1262915.BN574_01004	7.318e-10	72.0	COG2831@1|root,COG2831@2|Bacteria,1V0E1@1239|Firmicutes,4H3A8@909932|Negativicutes	909932|Negativicutes	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
YHH3_k127_5136393_7	1218084.BBJK01000017_gene1837	4.673e-41	160.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria,1K3NJ@119060|Burkholderiaceae	28216|Betaproteobacteria	U	family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Haemagg_act
YHH3_k127_5176583_1	419665.Maeo_1475	2.999e-05	51.0	COG1047@1|root,arCOG00980@2157|Archaea,2XTB7@28890|Euryarchaeota,23QFM@183939|Methanococci	183939|Methanococci	O	PFAM peptidylprolyl isomerase FKBP-type	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
YHH3_k127_5176583_0	1054217.TALC_00431	5.716e-71	251.0	COG1084@1|root,arCOG00352@2157|Archaea,2XU5R@28890|Euryarchaeota,241NE@183967|Thermoplasmata	183967|Thermoplasmata	S	Nucleolar GTP-binding protein 1 (NOG1)	-	-	-	ko:K06943	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	MMR_HSR1,NOG1
YHH3_k127_5178020_1	742817.HMPREF9449_02256	5.22e-53	196.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,2FNY8@200643|Bacteroidia,22WBG@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
YHH3_k127_5178020_0	762903.Pedsa_1202	1.339e-78	275.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1IQ2Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
YHH3_k127_5178020_2	525373.HMPREF0766_13155	8.21e-14	74.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
YHH3_k127_517988_4	382464.ABSI01000005_gene1342	1.986e-161	517.0	COG0448@1|root,COG0448@2|Bacteria,46SG2@74201|Verrucomicrobia,2IV7B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
YHH3_k127_517988_1	583355.Caka_2459	3.498e-260	815.0	COG0449@1|root,COG0449@2|Bacteria,46S94@74201|Verrucomicrobia,3K75B@414999|Opitutae	414999|Opitutae	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YHH3_k127_517988_3	794903.OPIT5_20520	8.192e-191	610.0	COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,3K72I@414999|Opitutae	414999|Opitutae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
YHH3_k127_517988_2	583355.Caka_2596	2.453e-228	713.0	COG0213@1|root,COG0213@2|Bacteria,46TUU@74201|Verrucomicrobia,3K74X@414999|Opitutae	414999|Opitutae	F	pyrimidine-nucleoside phosphorylase	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
YHH3_k127_517988_6	583355.Caka_1456	2.033e-91	308.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,3K7IJ@414999|Opitutae	414999|Opitutae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
YHH3_k127_517988_0	382464.ABSI01000012_gene2136	0.0	1014.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,2ITYS@203494|Verrucomicrobiae	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
YHH3_k127_517988_8	1051646.VITU9109_14061	8.472e-24	114.0	COG0265@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,1R6VW@1224|Proteobacteria,1SNEA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_517988_7	382464.ABSI01000005_gene1295	3.683e-49	181.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YHH3_k127_517988_5	1123508.JH636447_gene7881	6.135e-101	363.0	COG0515@1|root,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_8,WD40
YHH3_k127_518069_3	1123508.JH636448_gene7640	5.566e-98	331.0	COG0213@1|root,COG0213@2|Bacteria,2IY57@203682|Planctomycetes	203682|Planctomycetes	F	PFAM Glycosyl transferase, family	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
YHH3_k127_518069_2	452637.Oter_3082	3.536e-145	485.0	COG1158@1|root,COG1158@2|Bacteria,46S5Y@74201|Verrucomicrobia,3K7JV@414999|Opitutae	414999|Opitutae	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
YHH3_k127_518069_7	583355.Caka_1451	1.109e-35	143.0	COG0237@1|root,COG0237@2|Bacteria,46T2P@74201|Verrucomicrobia,3K83B@414999|Opitutae	414999|Opitutae	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
YHH3_k127_518069_6	452637.Oter_3080	2.39e-46	179.0	2CIBN@1|root,2Z8JT@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
YHH3_k127_518069_4	583355.Caka_2963	3.453e-67	236.0	COG4783@1|root,COG4783@2|Bacteria,46Z3R@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH3_k127_518069_0	583355.Caka_1463	0.0	1103.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,46SFK@74201|Verrucomicrobia,3K7FG@414999|Opitutae	414999|Opitutae	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
YHH3_k127_518069_9	278957.ABEA03000019_gene1945	0.0002096	46.0	2B8IX@1|root,321U3@2|Bacteria,46XWD@74201|Verrucomicrobia,3K8GM@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_518069_5	240016.ABIZ01000001_gene755	2.986e-53	194.0	COG2010@1|root,COG2010@2|Bacteria,46SVP@74201|Verrucomicrobia,2IUJ4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	N-terminal domain of cytochrome oxidase-cbb3, FixP	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,FixP_N
YHH3_k127_518069_1	382464.ABSI01000022_gene496	6.383e-161	520.0	COG0348@1|root,COG0348@2|Bacteria,46TZJ@74201|Verrucomicrobia,2ITW3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
YHH3_k127_5188572_1	479433.Caci_6648	0.0001171	52.0	COG2273@1|root,COG2273@2|Bacteria,2GKFN@201174|Actinobacteria	201174|Actinobacteria	G	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
YHH3_k127_5192228_5	1168034.FH5T_12950	7.341e-16	90.0	COG2972@1|root,COG2972@2|Bacteria,4NGA0@976|Bacteroidetes	976|Bacteroidetes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
YHH3_k127_5192228_0	521674.Plim_2153	6.817e-143	460.0	COG0191@1|root,COG0191@2|Bacteria,2IYZ9@203682|Planctomycetes	203682|Planctomycetes	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
YHH3_k127_5192228_6	596151.DesfrDRAFT_3920	6.323e-12	73.0	COG1309@1|root,COG1309@2|Bacteria,1N11B@1224|Proteobacteria,42ZYG@68525|delta/epsilon subdivisions,2WVGK@28221|Deltaproteobacteria,2MB4F@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
YHH3_k127_5192228_1	278957.ABEA03000054_gene1134	1.248e-108	361.0	COG0407@1|root,COG0407@2|Bacteria,46UU6@74201|Verrucomicrobia,3K7H3@414999|Opitutae	414999|Opitutae	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH3_k127_5192228_2	583355.Caka_0263	6.713e-63	227.0	COG0451@1|root,COG0451@2|Bacteria,46SWG@74201|Verrucomicrobia,3K80C@414999|Opitutae	414999|Opitutae	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YHH3_k127_5192228_3	382464.ABSI01000012_gene1989	4.005e-37	149.0	COG1514@1|root,COG1514@2|Bacteria,46SZP@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
YHH3_k127_5192228_4	1089550.ATTH01000001_gene726	3.296e-22	99.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1FJIM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YHH3_k127_5207601_2	382464.ABSI01000010_gene3353	1.779e-146	502.0	COG1629@1|root,COG1629@2|Bacteria	382464.ABSI01000010_gene3353|-	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5207601_1	1121904.ARBP01000009_gene4249	8.695e-184	584.0	COG4948@1|root,COG4948@2|Bacteria,4NI24@976|Bacteroidetes,47N24@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YHH3_k127_5207601_0	243090.RB5195	9.411e-198	627.0	COG3119@1|root,COG3119@2|Bacteria,2J1QG@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_5237633_1	330214.NIDE4316	2.747e-20	98.0	COG0389@1|root,COG0389@2|Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
YHH3_k127_5237633_0	452637.Oter_2661	2.05e-153	490.0	COG1063@1|root,COG1063@2|Bacteria,46UMA@74201|Verrucomicrobia,3KA31@414999|Opitutae	74201|Verrucomicrobia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_5241848_2	926569.ANT_16340	9.243e-05	46.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
YHH3_k127_5241848_0	1009370.ALO_05268	6.312e-46	174.0	COG0613@1|root,COG0613@2|Bacteria,1VCKE@1239|Firmicutes,4H57V@909932|Negativicutes	909932|Negativicutes	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
YHH3_k127_5241848_1	926569.ANT_19170	4.914e-08	65.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	ko:K04066,ko:K07037,ko:K17266	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400,ko04147	-	-	-	Band_7
YHH3_k127_5267496_3	929562.Emtol_1743	1.481e-16	79.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,47RGM@768503|Cytophagia	976|Bacteroidetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
YHH3_k127_5267496_2	1415780.JPOG01000001_gene2285	1.247e-52	189.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1X5XQ@135614|Xanthomonadales	135614|Xanthomonadales	S	EVE domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EVE
YHH3_k127_5267496_4	870187.Thini_1457	2.237e-11	69.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,4618R@72273|Thiotrichales	72273|Thiotrichales	J	RNA-binding protein	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
YHH3_k127_5267496_0	382464.ABSI01000005_gene1278	0.0	1075.0	COG0013@1|root,COG0013@2|Bacteria,46SAY@74201|Verrucomicrobia,2ITJJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YHH3_k127_5267496_1	452637.Oter_3663	6.439e-139	445.0	COG0473@1|root,COG0473@2|Bacteria,46TRZ@74201|Verrucomicrobia,3K7FD@414999|Opitutae	414999|Opitutae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH3_k127_5273266_2	504487.JCM19302_1254	6.144e-82	281.0	COG4975@1|root,COG4975@2|Bacteria	2|Bacteria	G	carbohydrate transmembrane transporter activity	glcU	GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659	-	ko:K05340,ko:K06216	-	-	-	-	ko00000,ko02000	2.A.7.5	-	-	Sugar_transport,Ureide_permease
YHH3_k127_5273266_0	1336803.PHEL49_1345	1.521e-293	919.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,3VW0S@52959|Polaribacter	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
YHH3_k127_5273266_4	1499967.BAYZ01000089_gene5047	4.05e-48	182.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	paaF	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01715,ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YHH3_k127_5273266_3	350688.Clos_0876	8.318e-75	265.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,36FMV@31979|Clostridiaceae	186801|Clostridia	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16,2.8.3.19	ko:K07749,ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
YHH3_k127_5273266_1	756272.Plabr_1070	1.899e-97	321.0	COG0657@1|root,COG3119@1|root,COG0657@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,Pectinesterase
YHH3_k127_5279439_0	314230.DSM3645_14360	7.956e-105	342.0	COG1215@1|root,COG1215@2|Bacteria,2IZ7V@203682|Planctomycetes	203682|Planctomycetes	M	COG0463 Glycosyltransferases involved in cell wall	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
YHH3_k127_5283306_2	583355.Caka_1813	1.39e-116	381.0	COG0492@1|root,COG0492@2|Bacteria,46SC1@74201|Verrucomicrobia,3K7S7@414999|Opitutae	414999|Opitutae	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YHH3_k127_5283306_6	278957.ABEA03000179_gene2885	8.191e-28	119.0	2EEN4@1|root,338G1@2|Bacteria,46T5X@74201|Verrucomicrobia,3K81C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5283306_0	583355.Caka_2088	2.625e-201	636.0	COG0621@1|root,COG0621@2|Bacteria,46S6B@74201|Verrucomicrobia,3K72N@414999|Opitutae	414999|Opitutae	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YHH3_k127_5283306_8	179408.Osc7112_3453	2.279e-12	72.0	COG0023@1|root,COG0023@2|Bacteria,1G6P3@1117|Cyanobacteria,1HBGR@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM translation initiation factor SUI1	sui1	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
YHH3_k127_5283306_5	583355.Caka_1306	2.106e-28	119.0	2EQTX@1|root,2ZQNF@2|Bacteria,46WYR@74201|Verrucomicrobia,3K8FD@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5283306_7	794903.OPIT5_17645	2.996e-22	99.0	COG1254@1|root,COG1254@2|Bacteria,46W9W@74201|Verrucomicrobia,3K8DW@414999|Opitutae	414999|Opitutae	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YHH3_k127_5283306_4	583355.Caka_2644	4.152e-36	145.0	2BXAM@1|root,2ZPRA@2|Bacteria,46VTF@74201|Verrucomicrobia,3K81N@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5283306_1	1121937.AUHJ01000011_gene2882	1.092e-153	491.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,1RMH8@1236|Gammaproteobacteria,465NV@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	transport system, permease component	yejB	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
YHH3_k127_5283306_3	314285.KT71_00420	1.675e-73	261.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,1J7FF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	yejE	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
YHH3_k127_5315573_0	335543.Sfum_1804	2.212e-225	707.0	COG1053@1|root,COG1148@1|root,COG1053@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
YHH3_k127_5334955_1	452637.Oter_3203	2.8e-08	61.0	COG1609@1|root,COG1609@2|Bacteria,46TVE@74201|Verrucomicrobia,3K935@414999|Opitutae	414999|Opitutae	K	PFAM regulatory protein LacI	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI
YHH3_k127_5334955_0	269797.Mbar_A1995	1.549e-94	334.0	arCOG02516@1|root,arCOG02538@1|root,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,2Y7RK@28890|Euryarchaeota,2NBKX@224756|Methanomicrobia	2157|Archaea	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,He_PIG,PKD,PQQ_3,Peptidase_S8,S-layer
YHH3_k127_5334955_2	1307759.JOMJ01000004_gene2438	4.946e-08	55.0	COG1846@1|root,COG1846@2|Bacteria,1N6T5@1224|Proteobacteria,42W44@68525|delta/epsilon subdivisions,2WRP5@28221|Deltaproteobacteria,2MFAX@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
YHH3_k127_5338037_0	1499967.BAYZ01000068_gene1935	3.553e-67	252.0	COG3266@1|root,COG3420@1|root,COG4733@1|root,COG3266@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,2NS5M@2323|unclassified Bacteria	2|Bacteria	P	Fibronectin type 3 domain	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CHB_HEX_C_1,CHU_C,DUF1573,DUF285,F5_F8_type_C,Laminin_G_3,Lectin_legB,fn3
YHH3_k127_5370103_2	706587.Desti_1873	2.065e-19	96.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria,43A0M@68525|delta/epsilon subdivisions,2X9UN@28221|Deltaproteobacteria,2MS7U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
YHH3_k127_5370103_1	416591.Tlet_1146	3.359e-21	108.0	COG3693@1|root,COG3693@2|Bacteria,2GE0R@200918|Thermotogae	200918|Thermotogae	G	Glycosyl hydrolase family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
YHH3_k127_5370103_0	385682.AFSL01000010_gene2403	1.66e-29	122.0	COG0666@1|root,COG0666@2|Bacteria,4NEYY@976|Bacteroidetes,2FVRK@200643|Bacteroidia	976|Bacteroidetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,Lipocalin_5,SHOCT,SecA_DEAD
YHH3_k127_537310_1	517418.Ctha_0502	4.323e-76	262.0	COG0577@1|root,COG0577@2|Bacteria,1FDCY@1090|Chlorobi	1090|Chlorobi	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
YHH3_k127_537310_0	517418.Ctha_0503	7.107e-94	314.0	COG1136@1|root,COG1136@2|Bacteria,1FDKJ@1090|Chlorobi	2|Bacteria	P	PFAM ABC transporter related	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_537310_2	517418.Ctha_0504	1.319e-14	81.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA_1	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
YHH3_k127_5376892_3	316274.Haur_0935	2.375e-25	108.0	COG3055@1|root,COG3055@2|Bacteria,2G6NU@200795|Chloroflexi	200795|Chloroflexi	KT	Kelch repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5376892_0	1174528.JH992898_gene1414	2.745e-84	294.0	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria,1JMXN@1189|Stigonemataceae	1117|Cyanobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CBS,CheB_methylest,CheR,CheR_N,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
YHH3_k127_5376892_2	1124780.ANNU01000006_gene2946	1.107e-45	174.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
YHH3_k127_5376892_1	926550.CLDAP_25210	1.168e-58	219.0	COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi	200795|Chloroflexi	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
YHH3_k127_5385133_0	583355.Caka_1488	1.548e-115	383.0	COG0702@1|root,COG0702@2|Bacteria,46W7M@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
YHH3_k127_5385133_1	326423.RBAM_029600	5.05e-44	176.0	COG2356@1|root,COG2356@2|Bacteria,1U9GI@1239|Firmicutes,4IJKB@91061|Bacilli,1ZAYK@1386|Bacillus	91061|Bacilli	L	Ribonuclease	bsn	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	Endonuclease_1
YHH3_k127_5385133_2	794903.OPIT5_21520	7.616e-05	55.0	COG1404@1|root,COG1404@2|Bacteria,46VVV@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5419461_0	1232410.KI421421_gene3328	9.062e-156	499.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,43S64@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
YHH3_k127_5419461_3	886379.AEWI01000004_gene888	9.451e-133	434.0	COG3507@1|root,COG3507@2|Bacteria,4NGKH@976|Bacteroidetes,2FP3Q@200643|Bacteroidia,3XKEY@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
YHH3_k127_5419461_1	391598.FBBAL38_11614	9.718e-156	497.0	2EXY1@1|root,33R74@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
YHH3_k127_5419461_4	1536772.R70723_27225	9.766e-118	386.0	COG0673@1|root,COG0673@2|Bacteria,1USVA@1239|Firmicutes,4HDVM@91061|Bacilli,26VU3@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_5419461_2	313628.LNTAR_06154	4.316e-135	449.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,SLH
YHH3_k127_543489_1	1449357.JQLK01000001_gene61	4.356e-70	241.0	COG0277@1|root,COG0277@2|Bacteria,1WIPW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM FAD linked oxidase domain protein	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YHH3_k127_543489_2	604331.AUHY01000007_gene730	5.556e-62	228.0	COG0277@1|root,COG0277@2|Bacteria,1WJI6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM FAD linked oxidase domain protein	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
YHH3_k127_543489_0	926560.KE387023_gene3407	1.7e-100	334.0	COG0247@1|root,COG0247@2|Bacteria,1WIQB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
YHH3_k127_5473560_3	1463887.KL590085_gene537	4.789e-34	153.0	COG1361@1|root,COG2706@1|root,COG1361@2|Bacteria,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,VCBS
YHH3_k127_5473560_4	111781.Lepto7376_0894	1.544e-17	99.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1GBAY@1117|Cyanobacteria	1117|Cyanobacteria	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
YHH3_k127_5473560_1	530564.Psta_3220	1.045e-71	268.0	COG1404@1|root,COG1404@2|Bacteria,2IY4U@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
YHH3_k127_5473560_5	349741.Amuc_0191	8.035e-05	51.0	2EJX7@1|root,33DMV@2|Bacteria,46WSK@74201|Verrucomicrobia,2IUU7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YHH3_k127_5473560_6	330214.NIDE0150	9.259e-05	53.0	2ETF9@1|root,33KZ8@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4412)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
YHH3_k127_5473560_0	1121396.KB893096_gene3529	4.29e-306	957.0	COG5360@1|root,COG5360@2|Bacteria,1R2H7@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
YHH3_k127_5473560_2	1123070.KB899248_gene216	2.67e-64	228.0	COG3440@1|root,COG3440@2|Bacteria,46XGT@74201|Verrucomicrobia,2IVVK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_2
YHH3_k127_5479584_0	452637.Oter_0026	2.359e-08	59.0	COG1957@1|root,COG1957@2|Bacteria,46UGB@74201|Verrucomicrobia,3K9ZR@414999|Opitutae	414999|Opitutae	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
YHH3_k127_5523087_0	439235.Dalk_2128	1.562e-107	372.0	COG5492@1|root,COG5492@2|Bacteria,1R8Z4@1224|Proteobacteria,42U3Q@68525|delta/epsilon subdivisions,2WQZX@28221|Deltaproteobacteria,2MKPP@213118|Desulfobacterales	28221|Deltaproteobacteria	N	PFAM Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566,Peptidase_C13
YHH3_k127_553899_9	748727.CLJU_c26590	6.619e-26	112.0	COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,249NM@186801|Clostridia,36FRH@31979|Clostridiaceae	186801|Clostridia	L	Spore photoproduct lyase	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
YHH3_k127_553899_8	1280696.ATVY01000001_gene3551	2.41e-28	130.0	COG0300@1|root,COG0300@2|Bacteria,1TRP8@1239|Firmicutes,24DNY@186801|Clostridia,4BZBF@830|Butyrivibrio	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH3_k127_553899_7	264732.Moth_1001	2.249e-32	129.0	COG3603@1|root,COG3603@2|Bacteria,1V9Y8@1239|Firmicutes,24JKN@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
YHH3_k127_553899_6	583355.Caka_2055	2.713e-42	162.0	COG0576@1|root,COG0576@2|Bacteria,46VZ0@74201|Verrucomicrobia,3K81S@414999|Opitutae	414999|Opitutae	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YHH3_k127_553899_1	382464.ABSI01000010_gene3750	2.688e-152	489.0	COG0484@1|root,COG0484@2|Bacteria,46TKC@74201|Verrucomicrobia,2ITUR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH3_k127_553899_4	278957.ABEA03000161_gene60	2.879e-69	239.0	COG0299@1|root,COG0299@2|Bacteria,46SS6@74201|Verrucomicrobia,3K74U@414999|Opitutae	414999|Opitutae	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
YHH3_k127_553899_3	452637.Oter_1674	5.561e-70	248.0	COG2264@1|root,COG2264@2|Bacteria,46SYY@74201|Verrucomicrobia,3K733@414999|Opitutae	414999|Opitutae	J	L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
YHH3_k127_553899_5	1541065.JRFE01000026_gene2122	5.916e-45	166.0	COG0824@1|root,COG0824@2|Bacteria,1G6JT@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
YHH3_k127_553899_0	382464.ABSI01000013_gene1575	7.699e-270	844.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
YHH3_k127_553899_2	382464.ABSI01000013_gene1576	1.206e-126	413.0	COG3069@1|root,COG3069@2|Bacteria	2|Bacteria	C	C4-dicarboxylate transmembrane transporter activity	-	-	-	ko:K03326	-	-	-	-	ko00000,ko02000	2.A.61.1	-	-	DcuC
YHH3_k127_5544722_2	382464.ABSI01000011_gene3153	1.886e-24	106.0	COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,2ITMG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Anticodon binding domain	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
YHH3_k127_5544722_0	382464.ABSI01000011_gene3071	2.851e-195	618.0	COG0008@1|root,COG0008@2|Bacteria,46SJ3@74201|Verrucomicrobia,2ITYY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH3_k127_5544722_1	583355.Caka_1921	1.249e-44	172.0	COG3608@1|root,COG3608@2|Bacteria	2|Bacteria	G	succinylglutamate desuccinylase aspartoacylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA,DUF2817
YHH3_k127_5544722_3	1150626.PHAMO_10150	1.505e-23	105.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TZDS@28211|Alphaproteobacteria,2JZ03@204441|Rhodospirillales	204441|Rhodospirillales	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
YHH3_k127_555447_0	313628.LNTAR_22714	7.144e-145	470.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_5554720_1	1197719.A464_2089	3.651e-09	59.0	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,1RRDM@1236|Gammaproteobacteria,3ZKHX@590|Salmonella	1236|Gammaproteobacteria	S	Uncharacterised protein family (UPF0149)	yecA	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
YHH3_k127_5554720_4	588581.Cpap_1096	4.548e-07	53.0	COG1484@1|root,COG1484@2|Bacteria,1TRWF@1239|Firmicutes,24FIP@186801|Clostridia,3WJT5@541000|Ruminococcaceae	186801|Clostridia	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
YHH3_k127_5554720_0	880072.Desac_1550	7.206e-65	227.0	COG0640@1|root,COG1669@1|root,COG0640@2|Bacteria,COG1669@2|Bacteria,1R18C@1224|Proteobacteria,43EID@68525|delta/epsilon subdivisions,2X8GT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5554720_3	439235.Dalk_0976	2.018e-07	53.0	COG1714@1|root,COG1714@2|Bacteria,1QDJB@1224|Proteobacteria,43858@68525|delta/epsilon subdivisions,2X0QR@28221|Deltaproteobacteria,2MPCF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
YHH3_k127_5572646_0	1379270.AUXF01000002_gene1826	2.968e-218	689.0	COG0843@1|root,COG0843@2|Bacteria,1ZSMG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
YHH3_k127_5572646_1	794903.OPIT5_28550	1.292e-88	305.0	COG1622@1|root,COG3474@1|root,COG1622@2|Bacteria,COG3474@2|Bacteria,46W3S@74201|Verrucomicrobia,3K7PR@414999|Opitutae	414999|Opitutae	C	Cytochrome c oxidase subunit	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
YHH3_k127_5572646_2	583355.Caka_0658	9.449e-81	279.0	COG0109@1|root,COG0109@2|Bacteria,46SQE@74201|Verrucomicrobia,3K7Y2@414999|Opitutae	414999|Opitutae	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
YHH3_k127_5572646_3	452637.Oter_2076	1.788e-67	241.0	COG1612@1|root,COG1612@2|Bacteria,46T3F@74201|Verrucomicrobia,3K7WI@414999|Opitutae	414999|Opitutae	O	cytochrome oxidase assembly	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
YHH3_k127_5572646_4	452637.Oter_2077	2.839e-57	209.0	COG1999@1|root,COG5569@1|root,COG1999@2|Bacteria,COG5569@2|Bacteria,46V8V@74201|Verrucomicrobia,3K7NQ@414999|Opitutae	414999|Opitutae	S	electron	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
YHH3_k127_5582947_0	383372.Rcas_3094	7.884e-131	421.0	COG1208@1|root,COG1208@2|Bacteria,2G863@200795|Chloroflexi,376T1@32061|Chloroflexia	32061|Chloroflexia	M	TIGRFAM glucose-1-phosphate cytidylyltransferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
YHH3_k127_5582947_1	266834.SM_b21056	2.356e-124	420.0	COG3291@1|root,COG3828@1|root,COG3291@2|Bacteria,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,UnbV_ASPIC,VCBS
YHH3_k127_560466_1	583355.Caka_1919	6.851e-124	401.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia,3K79V@414999|Opitutae	414999|Opitutae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH3_k127_560466_2	941449.dsx2_0721	3.855e-18	87.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WRRT@28221|Deltaproteobacteria,2MCID@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH3_k127_560466_0	382464.ABSI01000011_gene2741	0.0	1298.0	28HY3@1|root,2Z83I@2|Bacteria	2|Bacteria	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
YHH3_k127_5612795_9	794903.OPIT5_17690	3.563e-30	121.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,46S5K@74201|Verrucomicrobia,3K7D9@414999|Opitutae	414999|Opitutae	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
YHH3_k127_5612795_10	583355.Caka_1926	5.988e-30	125.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
YHH3_k127_5612795_11	382464.ABSI01000005_gene1400	1.333e-23	111.0	COG3332@1|root,COG3332@2|Bacteria,46W33@74201|Verrucomicrobia,2IWJ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
YHH3_k127_5612795_4	382464.ABSI01000005_gene1401	2.374e-115	392.0	COG0189@1|root,COG0586@1|root,COG0189@2|Bacteria,COG0586@2|Bacteria,46UXZ@74201|Verrucomicrobia	74201|Verrucomicrobia	HJ	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH3_k127_5612795_0	382464.ABSI01000005_gene1414	2.792e-213	677.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,46TH0@74201|Verrucomicrobia,2ITWG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase X family	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
YHH3_k127_5612795_6	1123070.KB899265_gene1827	1.269e-62	220.0	COG0229@1|root,COG0229@2|Bacteria,46TM8@74201|Verrucomicrobia,2IUM0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	SelR domain	-	-	-	-	-	-	-	-	-	-	-	-	SelR
YHH3_k127_5612795_3	583355.Caka_2212	4.184e-130	421.0	COG1469@1|root,COG1469@2|Bacteria,46URN@74201|Verrucomicrobia,3K79E@414999|Opitutae	414999|Opitutae	F	GTP cyclohydrolase	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
YHH3_k127_5612795_5	794903.OPIT5_28865	5.633e-80	276.0	COG1235@1|root,COG1235@2|Bacteria,46SKU@74201|Verrucomicrobia,3K7X5@414999|Opitutae	414999|Opitutae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
YHH3_k127_5612795_7	583355.Caka_1328	1.993e-44	168.0	COG0262@1|root,COG0262@2|Bacteria,46X6E@74201|Verrucomicrobia,3K9WI@414999|Opitutae	414999|Opitutae	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
YHH3_k127_5612795_2	1123393.KB891316_gene1344	4.035e-131	422.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,1KRFY@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
YHH3_k127_5612795_13	583355.Caka_2450	8.32e-16	80.0	28X6Y@1|root,2ZJ59@2|Bacteria,46WIZ@74201|Verrucomicrobia,3K8DC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5612795_1	583355.Caka_0388	1.05e-149	486.0	COG0151@1|root,COG0151@2|Bacteria,46SGJ@74201|Verrucomicrobia,3K7MF@414999|Opitutae	414999|Opitutae	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YHH3_k127_5612795_12	452637.Oter_0677	2.008e-21	102.0	COG2976@1|root,COG2976@2|Bacteria,46WP7@74201|Verrucomicrobia,3K88D@414999|Opitutae	414999|Opitutae	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
YHH3_k127_5612795_14	382464.ABSI01000012_gene2153	1.202e-13	81.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C
YHH3_k127_5612795_8	382464.ABSI01000012_gene2134	3.211e-35	141.0	COG0811@1|root,COG0811@2|Bacteria,46SY0@74201|Verrucomicrobia,2IUVE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH3_k127_561502_1	880073.Calab_3124	7.095e-64	221.0	COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria	2|Bacteria	S	lipopolysaccharide transport protein B ATP-binding component of ABC superfamily	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
YHH3_k127_561502_0	945713.IALB_2036	4.594e-189	597.0	COG0205@1|root,COG0205@2|Bacteria	2|Bacteria	G	6-phosphofructokinase activity	pfp	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135	2.7.1.11,2.7.1.90	ko:K00850,ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
YHH3_k127_5615863_0	187272.Mlg_2346	1.158e-137	448.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATPase, AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_5615863_1	583355.Caka_1948	8.865e-58	204.0	COG0339@1|root,COG0339@2|Bacteria,46TWS@74201|Verrucomicrobia,3K7KK@414999|Opitutae	414999|Opitutae	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
YHH3_k127_562227_1	644282.Deba_2761	2.123e-29	121.0	COG1983@1|root,COG1983@2|Bacteria,1PWDN@1224|Proteobacteria,42TA8@68525|delta/epsilon subdivisions,2WPVU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PspC domain protein	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
YHH3_k127_562227_0	56110.Oscil6304_3039	5.771e-88	303.0	COG0642@1|root,COG2205@2|Bacteria,1G3AM@1117|Cyanobacteria,1HA0Y@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,cNMP_binding
YHH3_k127_5628530_5	583355.Caka_2605	6.629e-46	168.0	COG0527@1|root,COG0527@2|Bacteria,46TWW@74201|Verrucomicrobia,3K7MP@414999|Opitutae	414999|Opitutae	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
YHH3_k127_5628530_2	794903.OPIT5_19750	4.786e-146	475.0	COG0460@1|root,COG0460@2|Bacteria,46TFC@74201|Verrucomicrobia,3K7MC@414999|Opitutae	414999|Opitutae	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
YHH3_k127_5628530_4	583355.Caka_2600	2.329e-52	191.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,3K83M@414999|Opitutae	414999|Opitutae	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
YHH3_k127_5628530_0	452637.Oter_3521	4.946e-178	574.0	COG1052@1|root,COG1052@2|Bacteria,46SAN@74201|Verrucomicrobia,3K77J@414999|Opitutae	414999|Opitutae	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH3_k127_5628530_1	583355.Caka_0673	6.046e-177	565.0	COG1249@1|root,COG1249@2|Bacteria,46S8I@74201|Verrucomicrobia,3K7TS@414999|Opitutae	414999|Opitutae	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH3_k127_5628530_3	382464.ABSI01000013_gene1810	4.347e-80	285.0	COG1594@1|root,COG1594@2|Bacteria,46XN4@74201|Verrucomicrobia,2IW8B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5644623_0	292415.Tbd_1072	3.676e-315	978.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VS7B@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
YHH3_k127_5671773_1	382464.ABSI01000005_gene1134	1.029e-147	474.0	COG2876@1|root,COG2876@2|Bacteria,46SUJ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
YHH3_k127_5671773_4	452637.Oter_3753	1.245e-51	192.0	COG0564@1|root,COG0564@2|Bacteria,46VI2@74201|Verrucomicrobia,3K84H@414999|Opitutae	414999|Opitutae	J	Pseudouridine synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
YHH3_k127_5671773_8	278957.ABEA03000029_gene1243	4.244e-16	90.0	2CGCF@1|root,33ZA6@2|Bacteria,46YV0@74201|Verrucomicrobia,3K85C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5671773_5	1403819.BATR01000049_gene1427	7.652e-38	150.0	COG0424@1|root,COG0424@2|Bacteria,46VR6@74201|Verrucomicrobia,2IUHS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Maf-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Maf
YHH3_k127_5671773_2	583355.Caka_2484	8.987e-91	308.0	COG1082@1|root,COG1082@2|Bacteria,46SWH@74201|Verrucomicrobia,3K7G6@414999|Opitutae	414999|Opitutae	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_5671773_7	452637.Oter_2093	1.002e-21	96.0	COG0828@1|root,COG0828@2|Bacteria,46WBR@74201|Verrucomicrobia,3K8F7@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
YHH3_k127_5671773_0	452637.Oter_1950	0.0	1250.0	COG0542@1|root,COG0542@2|Bacteria,46S4S@74201|Verrucomicrobia,3K798@414999|Opitutae	414999|Opitutae	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH3_k127_5671773_3	998674.ATTE01000001_gene3940	1.972e-86	298.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,460DW@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
YHH3_k127_5671773_6	1192034.CAP_7877	7.697e-27	114.0	COG4559@1|root,COG4559@2|Bacteria,1RD7N@1224|Proteobacteria,43BZU@68525|delta/epsilon subdivisions,2X7AK@28221|Deltaproteobacteria,2Z04C@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system	hmuV	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
YHH3_k127_5676637_0	658086.HMPREF0994_03659	1.106e-113	375.0	COG0407@1|root,COG0407@2|Bacteria,1V3M9@1239|Firmicutes,25AY7@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH3_k127_5676637_1	251229.Chro_3153	2.448e-32	134.0	COG2267@1|root,COG2267@2|Bacteria,1GIY6@1117|Cyanobacteria,3VMFU@52604|Pleurocapsales	1117|Cyanobacteria	I	Alpha/beta hydrolase of unknown function (DUF1057)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YHH3_k127_5726339_3	583355.Caka_2703	3.701e-160	508.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,3K7E9@414999|Opitutae	414999|Opitutae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH3_k127_5726339_20	661478.OP10G_0131	7.943e-06	48.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH3_k127_5726339_18	583355.Caka_2704	5.258e-18	87.0	COG0690@1|root,COG0690@2|Bacteria,46WU6@74201|Verrucomicrobia,3K8FP@414999|Opitutae	414999|Opitutae	U	Belongs to the SecE SEC61-gamma family	-	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
YHH3_k127_5726339_7	382464.ABSI01000011_gene2687	6.325e-80	270.0	COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,2IU6S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
YHH3_k127_5726339_9	382464.ABSI01000011_gene2686	7.593e-64	222.0	COG0080@1|root,COG0080@2|Bacteria,46SPZ@74201|Verrucomicrobia,2IUAM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
YHH3_k127_5726339_6	794903.OPIT5_04910	8.385e-81	275.0	COG0081@1|root,COG0081@2|Bacteria,46UQ6@74201|Verrucomicrobia,3K7JU@414999|Opitutae	414999|Opitutae	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
YHH3_k127_5726339_13	382464.ABSI01000011_gene2684	5.717e-52	188.0	COG0244@1|root,COG0244@2|Bacteria,46T4Q@74201|Verrucomicrobia,2IUF1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
YHH3_k127_5726339_14	382464.ABSI01000011_gene2683	1.286e-48	177.0	COG0222@1|root,COG0222@2|Bacteria,46SWC@74201|Verrucomicrobia,2IUI8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
YHH3_k127_5726339_1	583355.Caka_2710	0.0	2052.0	COG0085@1|root,COG0085@2|Bacteria,46S8Q@74201|Verrucomicrobia,3K77T@414999|Opitutae	414999|Opitutae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH3_k127_5726339_0	583355.Caka_2711	0.0	2149.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia,3K7EI@414999|Opitutae	414999|Opitutae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH3_k127_5726339_10	794903.OPIT5_02450	1.831e-62	217.0	COG0048@1|root,COG0048@2|Bacteria,46SQR@74201|Verrucomicrobia,3K7YQ@414999|Opitutae	414999|Opitutae	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
YHH3_k127_5726339_8	452637.Oter_0229	1.597e-71	244.0	COG0049@1|root,COG0049@2|Bacteria,46UH0@74201|Verrucomicrobia,3K7QA@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YHH3_k127_5726339_2	583355.Caka_1707	3.426e-318	988.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,3K7PT@414999|Opitutae	414999|Opitutae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YHH3_k127_5726339_12	452637.Oter_0227	2.252e-52	185.0	COG0051@1|root,COG0051@2|Bacteria,46SVV@74201|Verrucomicrobia,3K86C@414999|Opitutae	414999|Opitutae	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
YHH3_k127_5726339_5	583355.Caka_1690	2.592e-89	299.0	COG0087@1|root,COG0087@2|Bacteria,46U5V@74201|Verrucomicrobia,3K7BQ@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
YHH3_k127_5726339_11	794903.OPIT5_02425	2.631e-62	220.0	COG0088@1|root,COG0088@2|Bacteria,46SWJ@74201|Verrucomicrobia,3K7CA@414999|Opitutae	414999|Opitutae	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YHH3_k127_5726339_19	583355.Caka_1688	1.635e-17	85.0	COG0089@1|root,COG0089@2|Bacteria,46WBX@74201|Verrucomicrobia,3K884@414999|Opitutae	414999|Opitutae	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
YHH3_k127_5726339_4	583355.Caka_1687	1.058e-106	352.0	COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia,3K7DN@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YHH3_k127_5726339_16	382464.ABSI01000011_gene2666	4.945e-37	141.0	COG0185@1|root,COG0185@2|Bacteria,46T4G@74201|Verrucomicrobia,2IUPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
YHH3_k127_5726339_17	583355.Caka_1684	8.32e-36	138.0	COG0091@1|root,COG0091@2|Bacteria,46T5F@74201|Verrucomicrobia,3K89B@414999|Opitutae	414999|Opitutae	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
YHH3_k127_5726339_15	583355.Caka_1683	2.747e-48	177.0	COG0092@1|root,COG0092@2|Bacteria,46SN9@74201|Verrucomicrobia,3K776@414999|Opitutae	414999|Opitutae	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YHH3_k127_5752141_9	91464.S7335_4769	6.576e-50	183.0	COG2062@1|root,COG2062@2|Bacteria,1G74G@1117|Cyanobacteria	1117|Cyanobacteria	T	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
YHH3_k127_5752141_5	1121904.ARBP01000013_gene349	5.78e-109	367.0	COG4948@1|root,COG4948@2|Bacteria,4NKNN@976|Bacteroidetes,47JKW@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
YHH3_k127_5752141_15	382464.ABSI01000013_gene1592	4.496e-06	55.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_C
YHH3_k127_5752141_8	1304880.JAGB01000001_gene542	2.497e-56	211.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
YHH3_k127_5752141_2	243090.RB9146	3.929e-184	590.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
YHH3_k127_5752141_0	498211.CJA_2707	6.067e-241	757.0	COG1874@1|root,COG1874@2|Bacteria,1P0Y5@1224|Proteobacteria,1RZHZ@1236|Gammaproteobacteria,1FFWM@10|Cellvibrio	1236|Gammaproteobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_35,Glyco_hydro_42
YHH3_k127_5752141_3	382464.ABSI01000007_gene4181	9.498e-176	560.0	COG3345@1|root,COG3345@2|Bacteria,46UW0@74201|Verrucomicrobia,2IWQ9@203494|Verrucomicrobiae	2|Bacteria	G	Melibiase	rafA	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0005976,GO:0006080,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0051069,GO:0051682,GO:0071704,GO:1901575	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Dockerin_1,Glyco_hydro_36C,Glyco_hydro_36N,Melibiase,Melibiase_2,Melibiase_2_C
YHH3_k127_5752141_4	1124780.ANNU01000077_gene785	1.162e-147	481.0	COG1649@1|root,COG1649@2|Bacteria,4NJ45@976|Bacteroidetes,47JSI@768503|Cytophagia	976|Bacteroidetes	S	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
YHH3_k127_5752141_7	1499967.BAYZ01000019_gene6271	1.543e-94	318.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
YHH3_k127_5752141_1	382464.ABSI01000012_gene2052	1.198e-235	744.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,46TGA@74201|Verrucomicrobia,2IU20@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
YHH3_k127_5752141_12	382464.ABSI01000005_gene1127	7.29e-27	121.0	COG0810@1|root,COG0810@2|Bacteria,46W4X@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
YHH3_k127_5752141_10	382464.ABSI01000012_gene2154	1.27e-43	167.0	COG1595@1|root,COG1595@2|Bacteria,46VAA@74201|Verrucomicrobia,2IUMN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_5752141_14	1122927.KB895416_gene3585	1.652e-09	62.0	COG3507@1|root,COG3507@2|Bacteria,1UYIB@1239|Firmicutes,4HBKS@91061|Bacilli,26VC3@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
YHH3_k127_5752141_6	1041147.AUFB01000020_gene5430	6.472e-101	339.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TSBB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CE	Tartrate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH3_k127_5752141_11	143224.JQMD01000002_gene3084	3.593e-34	136.0	COG1878@1|root,COG1878@2|Bacteria,4NFYB@976|Bacteroidetes,1IIVK@117743|Flavobacteriia	976|Bacteroidetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YHH3_k127_5766557_0	595460.RRSWK_04080	4.507e-168	539.0	COG3669@1|root,COG3669@2|Bacteria,2J4D6@203682|Planctomycetes	203682|Planctomycetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
YHH3_k127_5766557_1	452637.Oter_2239	1.983e-35	143.0	COG2197@1|root,COG2197@2|Bacteria,46XU7@74201|Verrucomicrobia,3K85E@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_5776271_4	382464.ABSI01000005_gene1280	9.696e-07	54.0	COG0473@1|root,COG0473@2|Bacteria,46S4R@74201|Verrucomicrobia,2ITY1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH3_k127_5776271_6	583355.Caka_1593	0.0004893	51.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329,MucB_RseB,Sigma70_r2,Sigma70_r4_2
YHH3_k127_5776271_2	278957.ABEA03000180_gene2013	1.015e-136	448.0	COG1236@1|root,COG1236@2|Bacteria,46SQ0@74201|Verrucomicrobia,3K7R4@414999|Opitutae	414999|Opitutae	J	Beta-Casp domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,Lactamase_B,RMMBL
YHH3_k127_5776271_1	583355.Caka_1289	6.936e-241	754.0	COG0138@1|root,COG0138@2|Bacteria,46S5H@74201|Verrucomicrobia,3K7HP@414999|Opitutae	414999|Opitutae	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
YHH3_k127_5776271_3	583355.Caka_2018	2.458e-122	400.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia,3K77A@414999|Opitutae	414999|Opitutae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH3_k127_5776271_0	382464.ABSI01000011_gene3068	5.115e-246	780.0	COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia,2ITWU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
YHH3_k127_5776271_5	583355.Caka_1592	0.000131	49.0	2DPEK@1|root,331S2@2|Bacteria,46WT1@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5780952_1	903818.KI912268_gene1401	2.88e-06	49.0	COG1217@1|root,COG1217@2|Bacteria,3Y33Q@57723|Acidobacteria	57723|Acidobacteria	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
YHH3_k127_5780952_0	1392488.JHZY01000002_gene341	5.543e-110	374.0	COG5520@1|root,COG5520@2|Bacteria,4NEG7@976|Bacteroidetes,1HZPC@117743|Flavobacteriia,2XK4A@283735|Leeuwenhoekiella	976|Bacteroidetes	G	Glycosyl hydrolase family 30 beta sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydr_30_2,Glyco_hydro_30C
YHH3_k127_5806012_0	382464.ABSI01000009_gene3997	2.733e-187	595.0	COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia,2ITNR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
YHH3_k127_5810586_31	1132442.KB889752_gene2151	1.851e-06	52.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,1ZBI1@1386|Bacillus	91061|Bacilli	F	phosphorylase	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
YHH3_k127_5810586_13	326423.RBAM_021600	1.055e-80	281.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YHH3_k127_5810586_20	1303518.CCALI_02616	2.76e-60	214.0	COG0035@1|root,COG0035@2|Bacteria	2|Bacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11010	UPRTase
YHH3_k127_5810586_9	382464.ABSI01000010_gene3818	2.495e-117	392.0	COG2067@1|root,COG2067@2|Bacteria,46XGW@74201|Verrucomicrobia,2IVVS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
YHH3_k127_5810586_2	382464.ABSI01000010_gene3407	1.945e-220	696.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
YHH3_k127_5810586_29	1127692.HMPREF9075_02490	6.47e-10	71.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1HYW1@117743|Flavobacteriia,1EQCC@1016|Capnocytophaga	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_5810586_12	305900.GV64_01235	2.673e-92	312.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,1RSMJ@1236|Gammaproteobacteria,1XND5@135619|Oceanospirillales	135619|Oceanospirillales	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	-	-	-	-	-	-	-	-	-	-	OMPdecase
YHH3_k127_5810586_32	452637.Oter_2377	8.642e-06	52.0	2A19D@1|root,30PFV@2|Bacteria,46XVZ@74201|Verrucomicrobia,3K8F4@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5810586_24	1121481.AUAS01000012_gene314	9.546e-45	176.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
YHH3_k127_5810586_28	1538644.KO02_01345	3.614e-15	83.0	COG2259@1|root,COG2259@2|Bacteria,4NTM8@976|Bacteroidetes,1ITB2@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
YHH3_k127_5810586_7	583355.Caka_0015	1.84e-128	435.0	COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,3K8SD@414999|Opitutae	414999|Opitutae	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
YHH3_k127_5810586_11	583355.Caka_0017	9.097e-95	314.0	COG3880@1|root,COG3880@2|Bacteria,46SMN@74201|Verrucomicrobia,3K7MX@414999|Opitutae	414999|Opitutae	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
YHH3_k127_5810586_0	452637.Oter_3934	0.0	1187.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	414999|Opitutae	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
YHH3_k127_5810586_1	278957.ABEA03000189_gene958	3.314e-255	794.0	COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,3K751@414999|Opitutae	414999|Opitutae	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
YHH3_k127_5810586_19	278957.ABEA03000189_gene959	1.507e-65	228.0	COG2010@1|root,COG2010@2|Bacteria,46V1P@74201|Verrucomicrobia,3K7WS@414999|Opitutae	414999|Opitutae	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YHH3_k127_5810586_23	1396418.BATQ01000137_gene3872	2.785e-46	176.0	COG2010@1|root,COG2010@2|Bacteria,46SV4@74201|Verrucomicrobia,2IUCS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YHH3_k127_5810586_6	583355.Caka_0022	5.232e-138	450.0	COG4531@1|root,COG4531@2|Bacteria,46SME@74201|Verrucomicrobia,3K79U@414999|Opitutae	414999|Opitutae	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5810586_30	1210884.HG799462_gene8522	7.603e-09	59.0	2ETPP@1|root,33M7C@2|Bacteria,2J4FA@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5810586_3	583355.Caka_0025	2.613e-217	685.0	COG3278@1|root,COG3278@2|Bacteria,46T64@74201|Verrucomicrobia,3K7FT@414999|Opitutae	414999|Opitutae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
YHH3_k127_5810586_18	583355.Caka_0026	1.024e-68	240.0	COG2993@1|root,COG2993@2|Bacteria,46T1F@74201|Verrucomicrobia,3K82J@414999|Opitutae	414999|Opitutae	C	cytochrome c oxidase	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
YHH3_k127_5810586_25	583355.Caka_0027	2.587e-42	165.0	COG2010@1|root,COG2010@2|Bacteria,46T74@74201|Verrucomicrobia,3K83Q@414999|Opitutae	414999|Opitutae	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YHH3_k127_5810586_14	452637.Oter_3489	5.358e-78	266.0	COG2738@1|root,COG2738@2|Bacteria,46THF@74201|Verrucomicrobia,3K7WD@414999|Opitutae	414999|Opitutae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
YHH3_k127_5810586_15	583355.Caka_2390	2.542e-72	249.0	COG0461@1|root,COG0461@2|Bacteria,46SZV@74201|Verrucomicrobia,3K7GJ@414999|Opitutae	414999|Opitutae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YHH3_k127_5810586_16	1504981.KO116_3403	7.298e-71	250.0	COG2138@1|root,COG2138@2|Bacteria,1R8AE@1224|Proteobacteria,1S06H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cobalamin (vitamin B12) biosynthesis CbiX	-	-	-	-	-	-	-	-	-	-	-	-	CbiX
YHH3_k127_5810586_4	583355.Caka_2964	2.825e-167	538.0	COG0624@1|root,COG0624@2|Bacteria,46UH8@74201|Verrucomicrobia,3K7AU@414999|Opitutae	414999|Opitutae	E	peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YHH3_k127_5810586_8	1177181.T9A_00880	1.037e-119	392.0	COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,1RMX6@1236|Gammaproteobacteria,1XK94@135619|Oceanospirillales	135619|Oceanospirillales	S	COG0656 Aldo keto reductases, related to diketogulonate reductase	-	-	1.1.1.2	ko:K00002	ko00010,ko00040,ko00561,ko00930,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00561,map00930,map01100,map01110,map01120,map01130,map01220	M00014	R00746,R01041,R01481,R05231	RC00087,RC00088,RC00099,RC00108	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Aldo_ket_red
YHH3_k127_5810586_17	1250005.PHEL85_2107	2.338e-70	247.0	COG2755@1|root,COG2755@2|Bacteria,4NMPH@976|Bacteroidetes,1I197@117743|Flavobacteriia,3VXGB@52959|Polaribacter	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
YHH3_k127_5810586_26	314345.SPV1_08076	3.928e-24	104.0	2E4RC@1|root,32ZJW@2|Bacteria,1N8RU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5810586_5	1396141.BATP01000056_gene3263	1.273e-148	483.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	ynaJ	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2
YHH3_k127_5810586_10	1183438.GKIL_4354	4.324e-110	386.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_5810586_21	583355.Caka_1078	6.408e-54	196.0	COG4399@1|root,COG4399@2|Bacteria	2|Bacteria	-	-	yheB	-	-	-	-	-	-	-	-	-	-	-	DUF445
YHH3_k127_5810586_27	794903.OPIT5_13705	2.39e-21	102.0	COG2165@1|root,COG2165@2|Bacteria,46XPT@74201|Verrucomicrobia,3K9K3@414999|Opitutae	414999|Opitutae	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5810586_22	1231185.BAMP01000007_gene4158	2.118e-49	180.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TSX9@28211|Alphaproteobacteria,43HYK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	BQ	acetoin utilization protein	MA20_07590	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
YHH3_k127_5836564_13	358396.C445_08117	9.727e-10	62.0	COG1817@1|root,arCOG01395@2157|Archaea,2XT3W@28890|Euryarchaeota,23UIN@183963|Halobacteria	183963|Halobacteria	S	protein conserved in archaea	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
YHH3_k127_5836564_4	583355.Caka_2301	9.846e-102	342.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	arnC	-	2.4.1.83,2.4.2.53	ko:K00721,ko:K10012,ko:K20534	ko00510,ko00520,ko01100,ko01503,map00510,map00520,map01100,map01503	M00721,M00761	R01009,R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000	4.D.2.1.8,4.D.2.1.9	GT2	-	Glycos_transf_2
YHH3_k127_5836564_11	1249627.D779_2649	9.852e-25	112.0	COG0398@1|root,COG0398@2|Bacteria,1NPV8@1224|Proteobacteria,1SJGC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH3_k127_5836564_5	794903.OPIT5_07070	1.286e-97	333.0	COG1570@1|root,COG1570@2|Bacteria,46SCN@74201|Verrucomicrobia,3K7JQ@414999|Opitutae	414999|Opitutae	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
YHH3_k127_5836564_7	278957.ABEA03000188_gene1506	8.822e-76	264.0	COG2017@1|root,COG2017@2|Bacteria,46TTP@74201|Verrucomicrobia,3K7J7@414999|Opitutae	414999|Opitutae	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
YHH3_k127_5836564_12	382464.ABSI01000010_gene3839	4.392e-16	85.0	2960M@1|root,2ZTB9@2|Bacteria,46WKQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5836564_9	583355.Caka_3022	1.327e-53	197.0	COG0639@1|root,COG0639@2|Bacteria,46VJ1@74201|Verrucomicrobia,3K7WT@414999|Opitutae	414999|Opitutae	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH3_k127_5836564_6	1121406.JAEX01000019_gene2776	1.852e-84	296.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2M94B@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
YHH3_k127_5836564_10	794903.OPIT5_30585	2.863e-42	160.0	COG1959@1|root,COG1959@2|Bacteria,46VNQ@74201|Verrucomicrobia,3K872@414999|Opitutae	414999|Opitutae	K	TIGRFAM transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH3_k127_5836564_0	583355.Caka_2170	9.974e-276	876.0	COG2844@1|root,COG2844@2|Bacteria,46SI6@74201|Verrucomicrobia,3K7SE@414999|Opitutae	414999|Opitutae	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
YHH3_k127_5836564_1	583355.Caka_2169	7.71e-173	559.0	COG2203@1|root,COG3605@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG4191@2|Bacteria,46SAZ@74201|Verrucomicrobia,3K7H5@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
YHH3_k127_5836564_8	583355.Caka_2316	1.009e-63	224.0	COG1403@1|root,COG1403@2|Bacteria,46SMP@74201|Verrucomicrobia,3K7K4@414999|Opitutae	414999|Opitutae	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
YHH3_k127_5836564_2	595460.RRSWK_01778	2.383e-158	512.0	COG0469@1|root,COG0469@2|Bacteria,2IY60@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
YHH3_k127_5836564_3	583355.Caka_2914	6.022e-158	504.0	COG0001@1|root,COG0001@2|Bacteria,46TKU@74201|Verrucomicrobia,3K7DQ@414999|Opitutae	414999|Opitutae	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH3_k127_5839904_2	1121875.KB907548_gene1601	2.339e-23	109.0	2CF7X@1|root,34BKE@2|Bacteria,4P63S@976|Bacteroidetes,1IANS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5839904_1	748247.AZKH_4390	1.538e-30	124.0	COG0346@1|root,COG0346@2|Bacteria,1NB3U@1224|Proteobacteria,2W4TN@28216|Betaproteobacteria,2KZ57@206389|Rhodocyclales	206389|Rhodocyclales	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YHH3_k127_5839904_0	313628.LNTAR_16848	9.092e-48	181.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Esterase
YHH3_k127_5847796_2	1121403.AUCV01000007_gene1236	3.261e-55	203.0	28K48@1|root,2Z9T8@2|Bacteria,1NDBR@1224|Proteobacteria,43DM2@68525|delta/epsilon subdivisions,2X8SA@28221|Deltaproteobacteria,2MPIE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
YHH3_k127_5847796_1	935948.KE386494_gene874	3.83e-96	324.0	COG1082@1|root,COG1082@2|Bacteria,1V08R@1239|Firmicutes,24C9W@186801|Clostridia,42J0W@68295|Thermoanaerobacterales	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_5847796_0	526227.Mesil_0601	6.752e-145	475.0	COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
YHH3_k127_5847796_4	1121406.JAEX01000002_gene1141	0.0003688	44.0	COG0569@1|root,COG1226@1|root,COG0569@2|Bacteria,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria,42NKU@68525|delta/epsilon subdivisions,2WIRH@28221|Deltaproteobacteria,2M9MG@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
YHH3_k127_5847796_3	583355.Caka_1356	1.93e-20	93.0	COG0564@1|root,COG0564@2|Bacteria,46W71@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the pseudouridine synthase RluA family	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
YHH3_k127_5853766_2	1396418.BATQ01000142_gene3302	9.422e-155	496.0	COG1902@1|root,COG1902@2|Bacteria,46SGZ@74201|Verrucomicrobia,2ITH2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
YHH3_k127_5853766_1	497964.CfE428DRAFT_1758	0.0	1110.0	COG2838@1|root,COG2838@2|Bacteria,46TNM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM Isocitrate dehydrogenase NADP-dependent monomeric type	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
YHH3_k127_5853766_5	382464.ABSI01000011_gene2348	2.697e-21	103.0	COG0845@1|root,COG0845@2|Bacteria,46WQR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
YHH3_k127_5853766_0	382464.ABSI01000011_gene2351	0.0	1868.0	COG0841@1|root,COG0841@2|Bacteria,46Z6Y@74201|Verrucomicrobia,2ITZB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_5853766_3	382464.ABSI01000005_gene973	9.414e-93	314.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,2IUGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347,HlyD_D23
YHH3_k127_5869038_1	386456.JQKN01000002_gene2773	9.91e-24	110.0	COG0040@1|root,arCOG02208@2157|Archaea,2Y32G@28890|Euryarchaeota,23PBA@183925|Methanobacteria	183925|Methanobacteria	E	PFAM ATP phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HisG
YHH3_k127_5869038_0	497964.CfE428DRAFT_4797	1.501e-116	391.0	COG3866@1|root,COG3866@2|Bacteria,46SQX@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5875951_2	1185876.BN8_03376	5.864e-31	129.0	2BSEF@1|root,32MGE@2|Bacteria,4NK41@976|Bacteroidetes,47USI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5875951_0	1279009.ADICEAN_00881	5.128e-180	575.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47KDQ@768503|Cytophagia	976|Bacteroidetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
YHH3_k127_5875951_1	583355.Caka_2309	1.337e-85	293.0	COG1466@1|root,COG1466@2|Bacteria,46U09@74201|Verrucomicrobia,3K7M7@414999|Opitutae	414999|Opitutae	L	DNA polymerase III	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
YHH3_k127_5889594_4	452637.Oter_3364	7.438e-88	296.0	COG0404@1|root,COG0404@2|Bacteria,46UNP@74201|Verrucomicrobia,3K7HR@414999|Opitutae	414999|Opitutae	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YHH3_k127_5889594_0	382464.ABSI01000006_gene819	6.288e-184	584.0	COG3693@1|root,COG3693@2|Bacteria,46URW@74201|Verrucomicrobia,2IVBA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
YHH3_k127_5889594_3	382464.ABSI01000009_gene3964	1.54e-102	341.0	COG3970@1|root,COG3970@2|Bacteria,46S9N@74201|Verrucomicrobia,2IUA6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
YHH3_k127_5889594_2	344747.PM8797T_20758	2.271e-136	448.0	COG2610@1|root,COG2610@2|Bacteria,2J1TI@203682|Planctomycetes	203682|Planctomycetes	EG	COG2610 H gluconate symporter and related permeases	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
YHH3_k127_5889594_1	382464.ABSI01000005_gene1150	3.147e-158	506.0	COG2211@1|root,COG2211@2|Bacteria,46UNF@74201|Verrucomicrobia,2IV5Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
YHH3_k127_5982035_1	700598.Niako_0573	5.796e-18	86.0	COG1038@1|root,COG1038@2|Bacteria,4NFHU@976|Bacteroidetes,1IQ37@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	cfiB	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
YHH3_k127_5982035_0	509191.AEDB02000003_gene1106	2.333e-201	640.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae	186801|Clostridia	I	Carboxyl transferase domain	yqjD	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YHH3_k127_5982035_2	1235792.C808_04244	0.0008077	46.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,27N5U@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
YHH3_k127_5982334_1	243275.TDE_0687	1.869e-52	189.0	COG0041@1|root,COG0041@2|Bacteria,2J96B@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YHH3_k127_5982334_0	1313172.YM304_23690	2.32e-183	585.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CMWP@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
YHH3_k127_5982334_2	1321781.HMPREF1985_00296	2.637e-07	54.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YHH3_k127_5987740_0	382464.ABSI01000013_gene1571	3.777e-266	846.0	COG1572@1|root,COG3210@1|root,COG3386@1|root,COG4257@1|root,COG5373@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG4257@2|Bacteria,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	-	-	-	ko:K13277,ko:K15125,ko:K15539	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000,ko01002,ko03110	-	-	-	DUF5011
YHH3_k127_5987740_5	926550.CLDAP_31250	4.923e-06	53.0	2EEX1@1|root,338QB@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
YHH3_k127_5987740_1	382464.ABSI01000013_gene1572	3.443e-45	167.0	COG0664@1|root,COG0664@2|Bacteria,46X6S@74201|Verrucomicrobia,2IURE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
YHH3_k127_5987740_2	1499967.BAYZ01000097_gene4361	1.105e-41	160.0	COG0393@1|root,COG0393@2|Bacteria,2NPZJ@2323|unclassified Bacteria	2|Bacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
YHH3_k127_5987740_3	1499967.BAYZ01000097_gene4360	3.189e-36	142.0	COG0393@1|root,COG0393@2|Bacteria	2|Bacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
YHH3_k127_5987740_4	1499967.BAYZ01000097_gene4359	2.173e-26	117.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH3_k127_5990588_0	592026.GCWU0000282_002188	7.087e-63	237.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
YHH3_k127_5991138_1	1410626.JHXB01000021_gene1473	2.783e-39	151.0	COG0662@1|root,COG2089@1|root,COG0662@2|Bacteria,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia,27K4Z@186928|unclassified Lachnospiraceae	186801|Clostridia	M	SAF	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,NeuB
YHH3_k127_5991138_0	1304275.C41B8_09983	2.562e-108	361.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_600644_3	794903.OPIT5_10300	4.165e-53	194.0	COG0679@1|root,COG0679@2|Bacteria,46SPM@74201|Verrucomicrobia,3K77N@414999|Opitutae	414999|Opitutae	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
YHH3_k127_600644_5	497964.CfE428DRAFT_6076	1.489e-42	164.0	COG5530@1|root,COG5530@2|Bacteria	2|Bacteria	S	Predicted integral membrane protein (DUF2270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2270
YHH3_k127_600644_6	1101195.Meth11DRAFT_0216	2.374e-26	113.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KMXB@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
YHH3_k127_600644_4	56107.Cylst_5225	2.216e-49	187.0	29WGE@1|root,30I2I@2|Bacteria,1GFWI@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_600644_7	278957.ABEA03000060_gene3153	1.872e-23	111.0	COG2374@1|root,COG2374@2|Bacteria,46VEK@74201|Verrucomicrobia,3K81M@414999|Opitutae	414999|Opitutae	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH3_k127_600644_1	583355.Caka_1445	2.08e-154	501.0	COG0501@1|root,COG0501@2|Bacteria,46TVV@74201|Verrucomicrobia,3K72R@414999|Opitutae	414999|Opitutae	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
YHH3_k127_600644_8	794903.OPIT5_17250	1.48e-16	83.0	COG1722@1|root,COG1722@2|Bacteria,46TB2@74201|Verrucomicrobia,3K8ES@414999|Opitutae	414999|Opitutae	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
YHH3_k127_600644_0	583355.Caka_1052	6.858e-266	831.0	COG1154@1|root,COG1154@2|Bacteria,46SAU@74201|Verrucomicrobia,3K7CY@414999|Opitutae	414999|Opitutae	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
YHH3_k127_600644_2	1123355.JHYO01000014_gene1044	1.083e-123	413.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,36Z9W@31993|Methylocystaceae	28211|Alphaproteobacteria	V	AcrB/AcrD/AcrF family	ttgE	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
YHH3_k127_6028342_0	1336803.PHEL49_1349	0.0	1224.0	COG1520@1|root,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,1I4P5@117743|Flavobacteriia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ_2,PQQ_3
YHH3_k127_6028342_3	1117647.M5M_16980	1.035e-34	140.0	COG1802@1|root,COG1802@2|Bacteria,1Q2IV@1224|Proteobacteria,1S0EF@1236|Gammaproteobacteria,1JBKV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
YHH3_k127_6028342_1	504487.JCM19302_3662	2.26e-153	516.0	COG1520@1|root,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,1I4P5@117743|Flavobacteriia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ,PQQ_2,PQQ_3
YHH3_k127_6028342_5	452637.Oter_2257	1.49e-14	83.0	COG1651@1|root,COG4243@1|root,COG1651@2|Bacteria,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	dsbC	GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0055114,GO:0140096	5.3.4.1	ko:K01829,ko:K03673,ko:K03805,ko:K03981,ko:K12228	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko02044,ko03110	3.A.7.10.1,3.A.7.11.1	-	iE2348C_1286.E2348C_3146,iEC042_1314.EC042_3104,iECO111_1330.ECO111_0636,iECO26_1355.ECO26_0680,iEcE24377_1341.EcE24377A_0625,iEcSMS35_1347.EcSMS35_3026,iG2583_1286.G2583_0768,iPC815.YPO0891,iSFV_1184.SFV_2941,iSF_1195.SF2879,iSFxv_1172.SFxv_3158,iS_1188.S3078	DsbC_N,Thioredoxin_2,Thioredoxin_4,VKOR
YHH3_k127_6028342_4	382464.ABSI01000007_gene4166	2.139e-31	143.0	COG1629@1|root,COG1629@2|Bacteria,46UNV@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_6047439_1	1123070.KB899253_gene1090	9.235e-57	199.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	yodC	-	-	ko:K15976	-	-	-	-	ko00000,ko01000	-	-	-	Nitroreductase
YHH3_k127_6047439_2	194439.CT0599	7.433e-24	106.0	2E3B5@1|root,32YAP@2|Bacteria,1FE8N@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
YHH3_k127_6047439_0	1121921.KB898706_gene3211	1.56e-90	308.0	COG1409@1|root,COG1409@2|Bacteria,1NI34@1224|Proteobacteria,1S397@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH3_k127_6047439_3	883080.HMPREF9697_02843	7.041e-16	80.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,3JW9D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	MA20_44000	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_6054980_4	1121939.L861_22675	2.926e-66	242.0	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,1RMJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YHH3_k127_6054980_3	1121939.L861_22680	3.174e-78	268.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1XJ7N@135619|Oceanospirillales	1236|Gammaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
YHH3_k127_6054980_1	382464.ABSI01000023_gene585	7.392e-156	503.0	COG0621@1|root,COG0621@2|Bacteria,46S6B@74201|Verrucomicrobia,2ITRH@203494|Verrucomicrobiae	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
YHH3_k127_6054980_8	216432.CA2559_01825	5.404e-18	94.0	COG2356@1|root,COG2374@1|root,COG5337@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,COG5337@2|Bacteria,4NINJ@976|Bacteroidetes,1HZEY@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	LTD
YHH3_k127_6054980_9	382464.ABSI01000013_gene1714	0.0002575	49.0	COG2165@1|root,COG2165@2|Bacteria,46T3S@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH3_k127_6054980_5	452637.Oter_2046	9.161e-45	170.0	COG0466@1|root,COG0466@2|Bacteria,46WE2@74201|Verrucomicrobia,3K9NW@414999|Opitutae	414999|Opitutae	O	PFAM peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
YHH3_k127_6054980_0	583355.Caka_1083	4.022e-281	877.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia,3K7JR@414999|Opitutae	414999|Opitutae	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YHH3_k127_6054980_6	278957.ABEA03000180_gene2017	2.769e-34	133.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,3K8AV@414999|Opitutae	414999|Opitutae	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YHH3_k127_6054980_2	382464.ABSI01000006_gene754	4.931e-85	284.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,2ITQ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YHH3_k127_6058907_0	1411123.JQNH01000001_gene2243	1.476e-65	231.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,2TU5B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
YHH3_k127_6058907_2	290317.Cpha266_1381	4.861e-17	83.0	COG0864@1|root,COG0864@2|Bacteria	2|Bacteria	K	response to nickel cation	ndoAI	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	RHH_1
YHH3_k127_6058907_1	1121472.AQWN01000007_gene1058	3.729e-24	106.0	COG1569@1|root,COG1569@2|Bacteria,1VHAV@1239|Firmicutes,24QPU@186801|Clostridia,2671I@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH3_k127_6059236_4	1227352.C173_00802	1.781e-72	247.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4HBV7@91061|Bacilli,275E9@186822|Paenibacillaceae	91061|Bacilli	G	alpha-galactosidase	melA7	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
YHH3_k127_6059236_5	344747.PM8797T_13398	1.499e-66	233.0	COG3119@1|root,COG3119@2|Bacteria,2IWSZ@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_6059236_6	1268240.ATFI01000004_gene4390	3.246e-26	110.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,2FR8S@200643|Bacteroidia,4APFE@815|Bacteroidaceae	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_6059236_7	558152.IQ37_12790	8.029e-11	74.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia,3ZQX7@59732|Chryseobacterium	976|Bacteroidetes	G	Major facilitator transporter	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
YHH3_k127_6059236_3	1173026.Glo7428_0106	1.081e-72	265.0	COG4146@1|root,COG4146@2|Bacteria,1GR27@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_6059236_1	313628.LNTAR_11436	2.326e-127	421.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
YHH3_k127_6059236_0	1449063.JMLS01000027_gene52	3.868e-195	618.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,4HIHE@91061|Bacilli,26R8R@186822|Paenibacillaceae	91061|Bacilli	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_6059236_2	484018.BACPLE_00984	3.146e-77	278.0	COG5434@1|root,COG5434@2|Bacteria,4NID5@976|Bacteroidetes,2FMZR@200643|Bacteroidia,4AMUM@815|Bacteroidaceae	976|Bacteroidetes	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
YHH3_k127_6059236_8	452637.Oter_2495	3.014e-08	65.0	COG1629@1|root,COG1629@2|Bacteria,46UTS@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_6061685_1	1549858.MC45_05525	2.699e-35	149.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2U105@28211|Alphaproteobacteria,2K16Y@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YHH3_k127_6061685_0	756272.Plabr_3916	0.0	1294.0	COG0841@1|root,COG0841@2|Bacteria,2IX31@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_6061685_2	575540.Isop_1178	0.0006574	46.0	COG1538@1|root,COG1538@2|Bacteria,2IYWG@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_6070827_0	794903.OPIT5_27065	9.472e-109	399.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YHH3_k127_6070827_2	240016.ABIZ01000001_gene2277	2.414e-18	93.0	COG3209@1|root,COG4782@1|root,COG3209@2|Bacteria,COG4782@2|Bacteria,46S8F@74201|Verrucomicrobia,2IV48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
YHH3_k127_6070827_1	156578.ATW7_12648	6.421e-87	302.0	COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria,1RN0A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH3_k127_6100944_1	94122.Shewana3_2500	1.09e-136	461.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2NX@1236|Gammaproteobacteria,2Q91E@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH3_k127_6100944_2	945713.IALB_1748	1.827e-78	279.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_6100944_3	313594.PI23P_01762	3.934e-23	107.0	COG1564@1|root,COG1564@2|Bacteria,4NGJH@976|Bacteroidetes,1I37D@117743|Flavobacteriia,3VV4S@52959|Polaribacter	976|Bacteroidetes	H	Thiamin pyrophosphokinase, vitamin B1 binding domain	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
YHH3_k127_6100944_0	382464.ABSI01000010_gene3572	3.896e-181	574.0	COG1509@1|root,COG1509@2|Bacteria,46SVQ@74201|Verrucomicrobia,2ITNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Lysine-2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,LAM_C,Radical_SAM
YHH3_k127_6101370_0	583355.Caka_2353	6.188e-128	424.0	COG1196@1|root,COG1196@2|Bacteria,46TT8@74201|Verrucomicrobia,3K7E6@414999|Opitutae	414999|Opitutae	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YHH3_k127_6101370_1	1280953.HOC_07233	1.557e-30	134.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,2TUIR@28211|Alphaproteobacteria,43WUE@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH3_k127_6121601_0	382464.ABSI01000012_gene1972	9.508e-176	563.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46URT@74201|Verrucomicrobia,2IV35@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
YHH3_k127_6152366_0	583355.Caka_1628	6.602e-22	108.0	COG4726@1|root,COG4726@2|Bacteria	2|Bacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494
YHH3_k127_6152366_1	382464.ABSI01000013_gene1772	2.89e-18	94.0	299RH@1|root,2ZWTR@2|Bacteria,46WTD@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_618946_4	335543.Sfum_2123	1.447e-31	123.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2MQ6H@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
YHH3_k127_618946_0	583355.Caka_2357	1.444e-142	465.0	COG0141@1|root,COG0141@2|Bacteria,46SHG@74201|Verrucomicrobia,3K7N3@414999|Opitutae	414999|Opitutae	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
YHH3_k127_618946_1	583355.Caka_2359	4.169e-112	372.0	COG0079@1|root,COG0079@2|Bacteria,46TNF@74201|Verrucomicrobia,3K73Y@414999|Opitutae	414999|Opitutae	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_618946_2	794903.OPIT5_19830	9.413e-78	266.0	COG0131@1|root,COG0131@2|Bacteria,46UDT@74201|Verrucomicrobia,3K7V8@414999|Opitutae	414999|Opitutae	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
YHH3_k127_618946_3	583355.Caka_2361	5.463e-75	258.0	COG0118@1|root,COG0118@2|Bacteria,46V4G@74201|Verrucomicrobia,3K758@414999|Opitutae	414999|Opitutae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YHH3_k127_6194480_0	697281.Mahau_0767	9.564e-105	353.0	COG0407@1|root,COG0407@2|Bacteria,1V4WM@1239|Firmicutes,24IZV@186801|Clostridia,42J2I@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH3_k127_6194480_1	1521187.JPIM01000011_gene2619	0.0009645	43.0	COG1247@1|root,COG1670@1|root,COG1247@2|Bacteria,COG1670@2|Bacteria,2GA8C@200795|Chloroflexi	200795|Chloroflexi	JM	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH3_k127_6199833_8	221288.JH992901_gene4574	1.96e-43	160.0	COG0537@1|root,COG0537@2|Bacteria,1G6R2@1117|Cyanobacteria,1JITE@1189|Stigonemataceae	1117|Cyanobacteria	FG	HIT domain	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
YHH3_k127_6199833_4	452637.Oter_0180	2.963e-78	275.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia,3K7BD@414999|Opitutae	414999|Opitutae	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
YHH3_k127_6199833_0	583355.Caka_1832	1.425e-109	374.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,46S7Z@74201|Verrucomicrobia,3K7FH@414999|Opitutae	414999|Opitutae	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
YHH3_k127_6199833_7	278957.ABEA03000133_gene1582	1.223e-46	171.0	COG0736@1|root,COG0736@2|Bacteria,46T5U@74201|Verrucomicrobia,3K85Z@414999|Opitutae	414999|Opitutae	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
YHH3_k127_6199833_3	794903.OPIT5_25205	3.557e-89	301.0	COG0854@1|root,COG0854@2|Bacteria,46SJT@74201|Verrucomicrobia,3K74Q@414999|Opitutae	414999|Opitutae	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
YHH3_k127_6199833_6	794903.OPIT5_17270	1.649e-58	213.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia,3K7VV@414999|Opitutae	414999|Opitutae	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH3_k127_6199833_1	583355.Caka_2701	1.225e-106	355.0	COG1039@1|root,COG1039@2|Bacteria,46UEQ@74201|Verrucomicrobia,3K72V@414999|Opitutae	414999|Opitutae	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH3_k127_6199833_2	583355.Caka_2691	7.964e-96	324.0	COG1194@1|root,COG1194@2|Bacteria,46SR4@74201|Verrucomicrobia,3K760@414999|Opitutae	414999|Opitutae	L	iron-sulfur cluster	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YHH3_k127_6199833_5	583355.Caka_0983	4.672e-60	214.0	COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
YHH3_k127_6203279_1	794903.OPIT5_07795	3.872e-26	118.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529,ko:K03435,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
YHH3_k127_6203279_0	382464.ABSI01000005_gene1193	4.587e-83	284.0	COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia,2IU01@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YHH3_k127_6208376_0	278957.ABEA03000095_gene4621	4.692e-102	340.0	COG2152@1|root,COG2152@2|Bacteria,46YKJ@74201|Verrucomicrobia,3K8SE@414999|Opitutae	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
YHH3_k127_6243143_0	886293.Sinac_0555	1.444e-73	265.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_6243143_1	1349822.NSB1T_01840	1.543e-27	126.0	COG5434@1|root,COG5434@2|Bacteria,4NIYD@976|Bacteroidetes,2FRQ9@200643|Bacteroidia,23034@171551|Porphyromonadaceae	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Pectate_lyase_3
YHH3_k127_6272813_1	313628.LNTAR_07229	3.778e-157	502.0	COG3119@1|root,COG3119@2|Bacteria	313628.LNTAR_07229|-	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6272813_3	313628.LNTAR_22060	8.412e-86	308.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Beta_helix,CBM_6,DUF1565,F5_F8_type_C,PEGA,Trypsin_2
YHH3_k127_6272813_0	1396418.BATQ01000020_gene5046	1.278e-198	627.0	COG0477@1|root,COG2814@2|Bacteria,46TKN@74201|Verrucomicrobia,2IU9N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
YHH3_k127_6272813_2	314230.DSM3645_14985	3.647e-149	484.0	COG3119@1|root,COG3119@2|Bacteria,2IY75@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_6298388_1	401053.AciPR4_1981	5.009e-09	66.0	COG2945@1|root,COG2945@2|Bacteria,3Y35I@57723|Acidobacteria,2JIVZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
YHH3_k127_6298388_0	485913.Krac_5383	9.769e-22	101.0	COG0346@1|root,COG0622@1|root,COG0346@2|Bacteria,COG0622@2|Bacteria,2G8MU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH3_k127_6298388_2	313598.MED152_03070	1.973e-07	57.0	COG3296@1|root,COG3296@2|Bacteria,4NQGV@976|Bacteroidetes,1I2WN@117743|Flavobacteriia,3VWPV@52959|Polaribacter	976|Bacteroidetes	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870,SHOCT
YHH3_k127_6309267_0	583355.Caka_1909	3.765e-198	630.0	COG1109@1|root,COG1109@2|Bacteria,46SB1@74201|Verrucomicrobia,3K7CC@414999|Opitutae	414999|Opitutae	G	PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
YHH3_k127_6309267_1	794903.OPIT5_01475	1.733e-181	580.0	COG4284@1|root,COG4284@2|Bacteria,46U9U@74201|Verrucomicrobia,3K7T1@414999|Opitutae	414999|Opitutae	G	UTP--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.23,2.7.7.64,2.7.7.83	ko:K00972,ko:K12447	ko00040,ko00052,ko00053,ko00520,ko01100,ko01130,map00040,map00052,map00053,map00520,map01100,map01130	M00014,M00361,M00362	R00289,R00416,R00502,R01381,R03077,R08845	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
YHH3_k127_6309267_9	583355.Caka_1910	3.757e-11	67.0	COG2919@1|root,COG2919@2|Bacteria,46XW4@74201|Verrucomicrobia,3K8FZ@414999|Opitutae	414999|Opitutae	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
YHH3_k127_6309267_2	382464.ABSI01000005_gene1025	1.434e-103	342.0	COG3267@1|root,COG3267@2|Bacteria,46XMZ@74201|Verrucomicrobia,2IW82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
YHH3_k127_6309267_11	452637.Oter_3750	2.798e-08	64.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	agmX	-	-	ko:K07126,ko:K08930	ko02020,map02020	-	-	-	ko00000,ko00001,ko00194	-	-	-	DUF4339,SPOR,TPR_4,zinc_ribbon_4
YHH3_k127_6309267_3	583355.Caka_1343	1.109e-93	323.0	COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia,3K74C@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
YHH3_k127_6309267_5	888052.HMPREF9006_1734	1.455e-22	104.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4D4ET@85005|Actinomycetales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YHH3_k127_6309267_8	382464.ABSI01000013_gene1648	6.076e-15	80.0	COG2259@1|root,COG2259@2|Bacteria,46WSE@74201|Verrucomicrobia,2IWGT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	MauE
YHH3_k127_6309267_6	497964.CfE428DRAFT_0575	1.032e-18	91.0	COG0607@1|root,COG0607@2|Bacteria,46T32@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH3_k127_6309267_4	583355.Caka_1480	6.038e-47	175.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia,3K9TR@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_6309267_7	1121374.KB891591_gene3448	4.836e-16	85.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Peptidyl-prolyl cis-trans	mip	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
YHH3_k127_6321495_1	1121904.ARBP01000023_gene4974	2.024e-102	351.0	COG5434@1|root,COG5492@1|root,COG5434@2|Bacteria,COG5492@2|Bacteria,4NIYD@976|Bacteroidetes	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Pectate_lyase_3
YHH3_k127_6321495_3	483215.BACFIN_05600	2.451e-12	70.0	COG3119@1|root,COG3119@2|Bacteria,4NGJU@976|Bacteroidetes,2FQ5Y@200643|Bacteroidia,4APFT@815|Bacteroidaceae	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_6321495_0	1288963.ADIS_1398	6.531e-264	829.0	COG4692@1|root,COG4692@2|Bacteria,4NEYM@976|Bacteroidetes	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH3_k127_6321495_2	314230.DSM3645_18316	2.073e-92	312.0	COG3119@1|root,COG3119@2|Bacteria,2IXXP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_6363098_0	344747.PM8797T_25446	2.122e-250	788.0	COG0492@1|root,COG0492@2|Bacteria,2J52X@203682|Planctomycetes	203682|Planctomycetes	O	secreted protein-putative xanthan lyase related	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
YHH3_k127_6363098_1	1129794.C427_3392	4.827e-47	183.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,46CM3@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
YHH3_k127_6365913_0	298655.KI912266_gene746	1.643e-256	820.0	COG1061@1|root,COG1061@2|Bacteria,2GM8Z@201174|Actinobacteria,4ES7I@85013|Frankiales	201174|Actinobacteria	KL	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C
YHH3_k127_6365913_1	1121428.DESHY_160188___1	1.709e-71	260.0	COG0507@1|root,COG0507@2|Bacteria,1UJN1@1239|Firmicutes,24D34@186801|Clostridia,266M3@186807|Peptococcaceae	186801|Clostridia	L	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,DUF2075,NERD,ResIII,UvrD_C_2
YHH3_k127_6368432_1	760192.Halhy_2777	8.179e-48	175.0	COG3828@1|root,COG3828@2|Bacteria,4NNKV@976|Bacteroidetes	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_6368432_0	742727.HMPREF9447_02249	1.524e-105	358.0	COG3534@1|root,COG3534@2|Bacteria,4NGMQ@976|Bacteroidetes,2FN4W@200643|Bacteroidia,4API0@815|Bacteroidaceae	976|Bacteroidetes	G	Carbohydrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,DUF1080
YHH3_k127_6407776_1	583355.Caka_1197	1.527e-111	369.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,3K7QD@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YHH3_k127_6407776_0	794903.OPIT5_14400	6.396e-152	494.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia,3K788@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
YHH3_k127_6430585_2	1288963.ADIS_0233	0.0004135	46.0	COG3119@1|root,COG3119@2|Bacteria,4NETT@976|Bacteroidetes,47TM7@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_6430585_0	243090.RB352	4.205e-167	538.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_6430585_1	243090.RB2701	1.23e-17	86.0	COG3119@1|root,COG3119@2|Bacteria,2IXUK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_6441950_0	1123276.KB893301_gene4194	1.75e-82	285.0	COG1082@1|root,COG1082@2|Bacteria,4NJF5@976|Bacteroidetes,47MRZ@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH3_k127_6441950_1	1123242.JH636435_gene2622	1.752e-37	145.0	COG1680@1|root,COG2755@1|root,COG1680@2|Bacteria,COG2755@2|Bacteria,2IWSV@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH3_k127_645116_0	452637.Oter_2603	4.408e-207	658.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
YHH3_k127_645116_2	452637.Oter_0845	7.887e-69	246.0	COG2864@1|root,COG3005@1|root,COG2864@2|Bacteria,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
YHH3_k127_645116_1	452637.Oter_0845	7.579e-157	503.0	COG2864@1|root,COG3005@1|root,COG2864@2|Bacteria,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
YHH3_k127_645116_3	1128398.Curi_c11200	2.978e-14	73.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,268FB@186813|unclassified Clostridiales	186801|Clostridia	S	Haemolysin-III related	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
YHH3_k127_6478838_3	47839.CCAU010000009_gene1517	1.811e-55	204.0	COG2265@1|root,COG2265@2|Bacteria,2GWJH@201174|Actinobacteria,23C8P@1762|Mycobacteriaceae	201174|Actinobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
YHH3_k127_6478838_1	338969.Rfer_1241	1.568e-59	216.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2VP8N@28216|Betaproteobacteria,4AF40@80864|Comamonadaceae	28216|Betaproteobacteria	G	HpcH HpaI aldolase	-	-	4.1.2.20,4.1.2.52	ko:K01630,ko:K02510	ko00053,ko00350,ko01120,map00053,map00350,map01120	-	R01645,R01647,R02754,R03277	RC00307,RC00435,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
YHH3_k127_6478838_0	278957.ABEA03000117_gene1115	1.032e-95	319.0	COG1083@1|root,COG1083@2|Bacteria	2|Bacteria	M	cytidylyl-transferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,RraA-like
YHH3_k127_6478838_2	251221.35214356	2.108e-59	211.0	COG2604@1|root,COG2604@2|Bacteria,1G5GQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
YHH3_k127_6495024_1	1347342.BN863_19210	4.565e-125	411.0	2EWFV@1|root,33PU9@2|Bacteria,4P0Q6@976|Bacteroidetes,1I80X@117743|Flavobacteriia	976|Bacteroidetes	S	Hypothetical glycosyl hydrolase family 15	-	-	-	-	-	-	-	-	-	-	-	-	GHL15
YHH3_k127_6495024_0	1396418.BATQ01000175_gene2763	4.911e-171	551.0	COG3119@1|root,COG3119@2|Bacteria,46V0M@74201|Verrucomicrobia,2IU1S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
YHH3_k127_6495024_2	551275.KB899549_gene840	3.611e-41	158.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,43W8Z@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
YHH3_k127_6496315_0	382464.ABSI01000005_gene1020	6.951e-191	609.0	COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,2ITQ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	LeuA allosteric (dimerisation) domain	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
YHH3_k127_6496315_1	583355.Caka_1134	9.834e-151	496.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,46U4X@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
YHH3_k127_6506111_0	1121438.JNJA01000006_gene173	3.384e-100	341.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,2M9FS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Glycine radical	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
YHH3_k127_6506111_1	706587.Desti_2140	4.213e-94	316.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,43B8B@68525|delta/epsilon subdivisions,2X6MP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	glycyl-radical enzyme activating protein family	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
YHH3_k127_6509214_2	382464.ABSI01000010_gene3458	1.476e-05	52.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH3_k127_6509214_0	143224.JQMD01000002_gene197	1.577e-248	781.0	COG3055@1|root,COG5492@1|root,COG3055@2|Bacteria,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes,1HZEP@117743|Flavobacteriia	976|Bacteroidetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
YHH3_k127_6509214_1	342610.Patl_0831	1.669e-46	171.0	COG3669@1|root,COG3669@2|Bacteria,1N8B5@1224|Proteobacteria,1RWUY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	alpha-l-fucosidase	fucA1	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_6526213_0	880526.KE386488_gene1576	4.271e-94	339.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6526213_1	756272.Plabr_2893	9.555e-45	170.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
YHH3_k127_6526213_2	1156919.QWC_01085	1.026e-25	117.0	COG5316@1|root,COG5316@2|Bacteria,1N0IJ@1224|Proteobacteria,2VMTC@28216|Betaproteobacteria,3T365@506|Alcaligenaceae	28216|Betaproteobacteria	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
YHH3_k127_6528055_0	575540.Isop_0122	3.319e-109	365.0	COG1473@1|root,COG1473@2|Bacteria,2IY78@203682|Planctomycetes	203682|Planctomycetes	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YHH3_k127_6528055_1	344747.PM8797T_05430	3.9e-85	287.0	COG2170@1|root,COG2170@2|Bacteria,2IXAU@203682|Planctomycetes	203682|Planctomycetes	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
YHH3_k127_6529905_6	452637.Oter_0479	3.437e-19	88.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,3K7UD@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH3_k127_6529905_2	583355.Caka_2576	5.988e-89	295.0	COG1143@1|root,COG1143@2|Bacteria,46SNT@74201|Verrucomicrobia,3K7UR@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
YHH3_k127_6529905_4	382464.ABSI01000016_gene650	1.542e-37	147.0	COG0839@1|root,COG0839@2|Bacteria,46VSH@74201|Verrucomicrobia,2IUHV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YHH3_k127_6529905_5	382464.ABSI01000016_gene651	4.443e-29	119.0	COG0713@1|root,COG0713@2|Bacteria,46SX4@74201|Verrucomicrobia,2IUN3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YHH3_k127_6529905_0	382464.ABSI01000016_gene652	1.655e-211	674.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,2ITQ9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
YHH3_k127_6529905_1	583355.Caka_2580	3.861e-157	511.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,3K7GC@414999|Opitutae	414999|Opitutae	C	NADH-quinone oxidoreductase	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YHH3_k127_6529905_3	583355.Caka_2581	2.304e-50	188.0	COG1007@1|root,COG1007@2|Bacteria,46UXV@74201|Verrucomicrobia,3K7C5@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YHH3_k127_6532320_3	243090.RB1456	1.192e-14	74.0	COG3119@1|root,COG3119@2|Bacteria,2IXBF@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_6532320_0	1250005.PHEL85_1999	1.626e-245	772.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1HWZ1@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_6532320_1	1123242.JH636435_gene1778	5.928e-212	674.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_6532320_2	641524.ADICYQ_2001	3.157e-77	269.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.19,4.2.2.3	ko:K01729,ko:K19053	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	PL6	-	BACON,Chondroitinas_B,F5_F8_type_C
YHH3_k127_6536116_2	595460.RRSWK_03629	9.663e-73	254.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A	-	-	3.1.6.12	ko:K01135,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_6536116_1	756272.Plabr_3359	2.724e-117	386.0	COG3828@1|root,COG3828@2|Bacteria,2IY8Q@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
YHH3_k127_6536116_0	1121904.ARBP01000003_gene6415	7.574e-194	618.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_6549422_6	1434325.AZQN01000001_gene275	5.156e-31	129.0	COG1082@1|root,COG1082@2|Bacteria,4NFQY@976|Bacteroidetes,47KP7@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_6549422_4	1237149.C900_01360	3.671e-57	208.0	COG2133@1|root,COG4654@1|root,COG2133@2|Bacteria,COG4654@2|Bacteria,4NEMM@976|Bacteroidetes,47KXP@768503|Cytophagia	976|Bacteroidetes	CG	PFAM Cytochrome c, class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,DUF1080,PA14
YHH3_k127_6549422_0	583355.Caka_0532	3.636e-225	707.0	COG3119@1|root,COG3119@2|Bacteria,46UMG@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_6549422_3	1267535.KB906767_gene5360	4.628e-87	297.0	COG3622@1|root,COG3622@2|Bacteria,3Y6XP@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH3_k127_6549422_2	756272.Plabr_0527	3.468e-142	469.0	COG2610@1|root,COG2610@2|Bacteria,2IXVP@203682|Planctomycetes	203682|Planctomycetes	EG	COG2610 H gluconate symporter and related	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
YHH3_k127_6549422_1	1324957.K933_02146	2.416e-209	661.0	COG3119@1|root,arCOG02785@2157|Archaea,2XTTU@28890|Euryarchaeota,23UC8@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_6549422_5	509635.N824_28410	1.248e-43	165.0	COG4124@1|root,COG4124@2|Bacteria,4NEZG@976|Bacteroidetes,1IV70@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Glyco_hydro_26
YHH3_k127_6573121_3	583355.Caka_1846	1.41e-69	250.0	COG0265@1|root,COG0265@2|Bacteria,46T0K@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YHH3_k127_6573121_5	583355.Caka_2249	4.548e-37	148.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,3K80X@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
YHH3_k127_6573121_4	794903.OPIT5_19540	4.81e-61	220.0	COG0704@1|root,COG0704@2|Bacteria,46SUX@74201|Verrucomicrobia,3K824@414999|Opitutae	414999|Opitutae	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
YHH3_k127_6573121_2	313628.LNTAR_17343	9.97e-120	389.0	COG1117@1|root,COG1117@2|Bacteria	2|Bacteria	P	ATPase-coupled phosphate ion transmembrane transporter activity	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
YHH3_k127_6573121_1	1207063.P24_09261	2.354e-151	496.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,2JQA8@204441|Rhodospirillales	204441|Rhodospirillales	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
YHH3_k127_6573121_0	349741.Amuc_1305	5.632e-156	514.0	COG4590@1|root,COG4590@2|Bacteria	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YHH3_k127_6576081_0	227377.CBU_1788	9.033e-46	172.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
YHH3_k127_6576081_2	373994.Riv7116_4517	2.291e-26	120.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HJS7@1161|Nostocales	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,COR,LRR_4,LRR_8,Roc
YHH3_k127_6576081_1	313628.LNTAR_11911	1.995e-38	160.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase,Lipase_GDSL_2,Peptidase_S9
YHH3_k127_6576081_3	880073.Calab_0641	3.045e-24	118.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	GxGYxYP_C,GxGYxYP_N,PTPlike_phytase
YHH3_k127_6581704_2	382464.ABSI01000013_gene1773	4.468e-19	92.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6581704_0	382464.ABSI01000020_gene286	1.426e-305	952.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
YHH3_k127_6581704_1	518766.Rmar_0584	2.794e-62	218.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
YHH3_k127_6591052_0	595460.RRSWK_04037	3.375e-214	675.0	COG3119@1|root,COG3119@2|Bacteria,2IXIE@203682|Planctomycetes	2|Bacteria	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
YHH3_k127_6591052_3	452637.Oter_3766	2.563e-141	489.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_6591052_7	1328313.DS2_06761	7.13e-67	233.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,465FY@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	narL	-	-	ko:K02479,ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
YHH3_k127_6591052_4	1328313.DS2_06756	5.214e-123	420.0	COG2010@1|root,COG4585@1|root,COG2010@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C,Cytochrome_CBB3,HisKA_3
YHH3_k127_6591052_2	1265503.KB905169_gene268	5.565e-144	478.0	COG1874@1|root,COG1874@2|Bacteria,1R702@1224|Proteobacteria,1RUC4@1236|Gammaproteobacteria	1224|Proteobacteria	G	Beta-galactosidase	-	-	3.2.1.81	ko:K01219	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_42
YHH3_k127_6591052_5	278957.ABEA03000092_gene4478	1.633e-77	272.0	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia,3K7J5@414999|Opitutae	414999|Opitutae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
YHH3_k127_6591052_10	583355.Caka_2084	2.504e-40	154.0	COG2026@1|root,COG2026@2|Bacteria,46VPJ@74201|Verrucomicrobia,3K85V@414999|Opitutae	414999|Opitutae	DJ	Addiction module toxin, RelE StbE family	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	-
YHH3_k127_6591052_1	583355.Caka_2082	2.694e-165	527.0	COG0592@1|root,COG0592@2|Bacteria,46UBP@74201|Verrucomicrobia,3K7UX@414999|Opitutae	414999|Opitutae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
YHH3_k127_6591052_6	452637.Oter_0952	1.561e-68	243.0	2EXV9@1|root,33R4E@2|Bacteria,46UMS@74201|Verrucomicrobia,3K7QR@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6591052_9	583355.Caka_2757	8.568e-44	166.0	COG2227@1|root,COG2227@2|Bacteria,46Z2T@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
YHH3_k127_6591052_8	583355.Caka_1730	3.123e-50	183.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03207,ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YHH3_k127_6591052_11	1121439.dsat_0260	7.626e-40	159.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2X2GQ@28221|Deltaproteobacteria,2MC2F@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
YHH3_k127_6605094_8	56780.SYN_02742	4.179e-59	218.0	arCOG09742@1|root,2ZBGR@2|Bacteria,1R9H3@1224|Proteobacteria,42XHN@68525|delta/epsilon subdivisions,2WT8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6605094_10	1123057.P872_20990	1.047e-24	107.0	2EGU1@1|root,33AK7@2|Bacteria,4P5VY@976|Bacteroidetes,47W7Q@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6605094_18	41431.PCC8801_4318	0.0002281	47.0	COG1598@1|root,COG1598@2|Bacteria,1G92J@1117|Cyanobacteria,3KKJI@43988|Cyanothece	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6605094_14	105559.Nwat_2566	6.384e-17	83.0	COG1724@1|root,COG1724@2|Bacteria,1Q0UZ@1224|Proteobacteria,1SRX7@1236|Gammaproteobacteria,1X190@135613|Chromatiales	135613|Chromatiales	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH3_k127_6605094_5	452637.Oter_1808	1.936e-77	272.0	COG2378@1|root,COG2378@2|Bacteria,46VG3@74201|Verrucomicrobia,3K846@414999|Opitutae	414999|Opitutae	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
YHH3_k127_6605094_15	102125.Xen7305DRAFT_00050770	5.467e-16	83.0	29WKM@1|root,30I78@2|Bacteria,1GG4U@1117|Cyanobacteria,3VN6N@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6605094_16	1454004.AW11_02027	1.617e-12	70.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	sohA	GO:0001558,GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040008,GO:0042802,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K19156	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin,PrlF_antitoxin
YHH3_k127_6605094_1	382464.ABSI01000023_gene553	1.703e-142	465.0	COG0285@1|root,COG0285@2|Bacteria,46SKD@74201|Verrucomicrobia,2ITNW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH3_k127_6605094_3	583355.Caka_1971	1.857e-105	349.0	COG0777@1|root,COG0777@2|Bacteria,46V0X@74201|Verrucomicrobia,3K7C6@414999|Opitutae	414999|Opitutae	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YHH3_k127_6605094_9	583355.Caka_1972	1.332e-48	183.0	COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia,3K7XA@414999|Opitutae	414999|Opitutae	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6605094_13	382464.ABSI01000002_gene4332	1.224e-18	98.0	COG1266@1|root,COG1266@2|Bacteria,46WKN@74201|Verrucomicrobia,2IUVF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
YHH3_k127_6605094_2	583355.Caka_1594	3.342e-133	461.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46W2M@74201|Verrucomicrobia,3K81K@414999|Opitutae	2|Bacteria	KLT	Sulfatase-modifying factor enzyme 1	egtB	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
YHH3_k127_6605094_12	1415780.JPOG01000001_gene3274	1.175e-18	96.0	COG2430@1|root,COG2430@2|Bacteria,1REND@1224|Proteobacteria,1S94F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF432
YHH3_k127_6605094_6	583355.Caka_1595	8.044e-65	229.0	COG0452@1|root,COG0452@2|Bacteria,46SPU@74201|Verrucomicrobia,3K88J@414999|Opitutae	414999|Opitutae	H	Flavoprotein	-	-	4.1.1.36	ko:K01598	ko00770,ko01100,map00770,map01100	M00120	R03269	RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
YHH3_k127_6605094_17	1121904.ARBP01000001_gene5501	8.269e-10	66.0	COG1714@1|root,COG1714@2|Bacteria,4NWCH@976|Bacteroidetes,47WHE@768503|Cytophagia	976|Bacteroidetes	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
YHH3_k127_6605094_0	583355.Caka_1596	1.593e-230	725.0	COG0119@1|root,COG0119@2|Bacteria,46TI3@74201|Verrucomicrobia,3K7IC@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
YHH3_k127_6605094_4	589865.DaAHT2_0683	4.068e-82	282.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria,2MIQY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
YHH3_k127_6605094_7	177437.HRM2_12140	4.319e-60	216.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria,2MHMM@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
YHH3_k127_6605094_11	1167006.UWK_01844	9.772e-22	97.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WJYG@28221|Deltaproteobacteria,2MJBW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
YHH3_k127_660556_1	886293.Sinac_4629	6.023e-65	230.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_660556_2	344747.PM8797T_00157	7.238e-47	175.0	COG3119@1|root,COG3119@2|Bacteria,2J1S4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_660556_0	240016.ABIZ01000001_gene4661	4.282e-83	282.0	COG3119@1|root,COG3119@2|Bacteria,46U02@74201|Verrucomicrobia,2ITYT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_660575_0	583355.Caka_0618	2.897e-158	513.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Exo_endo_phos,Phytase-like,VPEP
YHH3_k127_6614535_0	583355.Caka_2713	3.487e-54	207.0	COG4782@1|root,COG4782@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
YHH3_k127_6614535_1	1499967.BAYZ01000093_gene4035	2.364e-20	102.0	28RXC@1|root,2ZE9F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6614535_2	583355.Caka_1554	1.224e-12	72.0	COG2839@1|root,COG2839@2|Bacteria,46WB1@74201|Verrucomicrobia,3K8HU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
YHH3_k127_6627068_8	1396418.BATQ01000044_gene6481	8.054e-10	63.0	COG0268@1|root,COG0268@2|Bacteria,46WWC@74201|Verrucomicrobia,2IV02@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S20	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
YHH3_k127_6627068_7	290315.Clim_1265	3.466e-29	126.0	COG0847@1|root,COG0847@2|Bacteria,1FDW7@1090|Chlorobi	1090|Chlorobi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
YHH3_k127_6627068_3	517418.Ctha_1748	2.251e-91	325.0	COG2905@1|root,COG2905@2|Bacteria,1FDR9@1090|Chlorobi	1090|Chlorobi	T	CBS domain containing protein	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
YHH3_k127_6627068_4	1123070.KB899251_gene793	1.464e-85	292.0	COG0688@1|root,COG0688@2|Bacteria,46TND@74201|Verrucomicrobia,2ITXF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phosphatidylserine decarboxylase	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
YHH3_k127_6627068_5	278957.ABEA03000203_gene2698	7.343e-50	184.0	COG0847@1|root,COG0847@2|Bacteria,46VEF@74201|Verrucomicrobia,3K7YC@414999|Opitutae	414999|Opitutae	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	-
YHH3_k127_6627068_0	382464.ABSI01000002_gene4337	1.52e-204	654.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia,2ITX2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YHH3_k127_6627068_1	794903.OPIT5_13850	8.66e-110	366.0	COG0006@1|root,COG0006@2|Bacteria,46SKG@74201|Verrucomicrobia,3K72M@414999|Opitutae	414999|Opitutae	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH3_k127_6627068_6	278957.ABEA03000080_gene3216	3.205e-35	142.0	COG1430@1|root,COG1430@2|Bacteria,46WD4@74201|Verrucomicrobia,3K83W@414999|Opitutae	414999|Opitutae	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
YHH3_k127_6627068_2	583355.Caka_0677	4.781e-94	317.0	COG1167@1|root,COG1167@2|Bacteria,46TGY@74201|Verrucomicrobia,3K7IS@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH3_k127_6637671_1	1178825.ALIH01000015_gene1934	3.635e-134	451.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.14.10	ko:K01280	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	PPC,Peptidase_S8
YHH3_k127_6637671_0	313628.LNTAR_08629	2.278e-232	738.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	1.4.3.16,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00278,ko:K03388	ko00250,ko00680,ko00760,ko01100,ko01120,ko01200,map00250,map00680,map00760,map01100,map01120,map01200	M00115,M00356,M00357,M00563,M00567	R00357,R00481,R04540,R11928,R11931,R11943,R11944	RC00006,RC00011,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
YHH3_k127_6637671_2	382464.ABSI01000007_gene4178	3.026e-50	185.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
YHH3_k127_6637671_3	880070.Cycma_4970	5.083e-33	132.0	COG1082@1|root,COG1082@2|Bacteria,4NHJE@976|Bacteroidetes,47NW1@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_6643272_2	344747.PM8797T_13173	2.065e-79	279.0	COG0657@1|root,COG0657@2|Bacteria,2J37Q@203682|Planctomycetes	203682|Planctomycetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
YHH3_k127_6643272_0	1403819.BATR01000070_gene2104	1.438e-122	406.0	COG0577@1|root,COG0577@2|Bacteria,46TQS@74201|Verrucomicrobia,2IWMB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_6643272_1	240016.ABIZ01000001_gene5156	1.23e-82	280.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,2IUA4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_6664629_0	452637.Oter_1349	1.736e-49	197.0	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,46UNV@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_6664629_1	1123508.JH636460_gene188	4.325e-49	183.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
YHH3_k127_6664629_2	1401078.HMPREF2140_03240	6.429e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,2FMHN@200643|Bacteroidia	976|Bacteroidetes	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8
YHH3_k127_6671949_7	291112.PAU_01985	7.049e-05	53.0	2CK9T@1|root,2Z7W9@2|Bacteria,1NEP3@1224|Proteobacteria,1S0HF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6671949_4	1033732.CAHI01000022_gene1516	5.459e-165	539.0	COG3119@1|root,COG3533@1|root,COG3119@2|Bacteria,COG3533@2|Bacteria,4NF1X@976|Bacteroidetes,2G20J@200643|Bacteroidia,22VAP@171550|Rikenellaceae	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_6671949_1	1033732.CAHI01000022_gene1516	2.545e-198	631.0	COG3119@1|root,COG3533@1|root,COG3119@2|Bacteria,COG3533@2|Bacteria,4NF1X@976|Bacteroidetes,2G20J@200643|Bacteroidia,22VAP@171550|Rikenellaceae	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_6671949_6	1121904.ARBP01000010_gene2297	4.495e-103	343.0	COG0524@1|root,COG0524@2|Bacteria,4NENQ@976|Bacteroidetes,47MN5@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH3_k127_6671949_3	760192.Halhy_3361	7.924e-177	564.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,1IRRN@117747|Sphingobacteriia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
YHH3_k127_6671949_2	1123057.P872_02175	9.155e-198	628.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,47KMG@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH3_k127_6671949_5	1122179.KB890429_gene3700	4.65e-134	441.0	COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,1IY8C@117747|Sphingobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
YHH3_k127_6671949_0	382464.ABSI01000013_gene1570	1.325e-306	961.0	COG2114@1|root,COG3899@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,46U27@74201|Verrucomicrobia	74201|Verrucomicrobia	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
YHH3_k127_66824_3	450851.PHZ_c0675	5.825e-19	93.0	2DBU1@1|root,2ZB3C@2|Bacteria,1NB4B@1224|Proteobacteria,2U0ZG@28211|Alphaproteobacteria,2KHJR@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_66824_2	317936.Nos7107_3521	1.552e-26	114.0	2BK9M@1|root,32EPT@2|Bacteria,1G703@1117|Cyanobacteria,1HS5Z@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_66824_4	1121405.dsmv_0920	4.315e-12	72.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WNC2@28221|Deltaproteobacteria,2MK0D@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
YHH3_k127_66824_0	497964.CfE428DRAFT_3705	1.059e-75	258.0	296ZZ@1|root,2ZU8H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_66824_1	1121904.ARBP01000007_gene2889	3.981e-53	196.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,47MB7@768503|Cytophagia	976|Bacteroidetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH3_k127_668587_0	1203611.KB894556_gene1940	1.052e-184	595.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,2FPXE@200643|Bacteroidia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
YHH3_k127_677203_0	452637.Oter_3270	1.266e-20	102.0	COG1269@1|root,COG1269@2|Bacteria,46T89@74201|Verrucomicrobia,3K83T@414999|Opitutae	414999|Opitutae	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
YHH3_k127_677203_1	452637.Oter_3270	2.324e-13	78.0	COG1269@1|root,COG1269@2|Bacteria,46T89@74201|Verrucomicrobia,3K83T@414999|Opitutae	414999|Opitutae	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
YHH3_k127_6777697_0	1198232.CYCME_0977	7.465e-253	789.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,45ZSF@72273|Thiotrichales	72273|Thiotrichales	E	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
YHH3_k127_6777697_1	1198232.CYCME_0978	3.021e-64	222.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,1RP49@1236|Gammaproteobacteria,461NK@72273|Thiotrichales	72273|Thiotrichales	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
YHH3_k127_6796270_3	344747.PM8797T_30998	5.63e-194	615.0	COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,2IWSF@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	2.4.1.14,2.4.1.246	ko:K00696,ko:K13058	ko00500,ko01100,map00500,map01100	-	R00766,R08947	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1,S6PP
YHH3_k127_6796270_0	344747.PM8797T_31003	4.031e-256	804.0	COG0366@1|root,COG0366@2|Bacteria,2J4ZQ@203682|Planctomycetes	203682|Planctomycetes	G	Maltogenic Amylase, C-terminal domain	-	-	2.4.1.4	ko:K05341	ko00500,map00500	-	R01823	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
YHH3_k127_6796270_4	756272.Plabr_4269	5.051e-137	449.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
YHH3_k127_6796270_9	880072.Desac_0769	3.826e-09	69.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,42VG3@68525|delta/epsilon subdivisions,2WRB7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6796270_7	382464.ABSI01000005_gene1295	1.724e-58	209.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YHH3_k127_6796270_1	382464.ABSI01000005_gene1296	3.783e-247	793.0	COG0457@1|root,COG0515@1|root,COG3291@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3291@2|Bacteria,46UMT@74201|Verrucomicrobia,2IVH7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PEGA,PG_binding_1,Pkinase
YHH3_k127_6796270_6	523791.Kkor_0590	6.256e-81	278.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1XRBY@135619|Oceanospirillales	135619|Oceanospirillales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH3_k127_6796270_5	1396141.BATP01000007_gene5629	1.559e-87	304.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH3_k127_6796270_8	1396418.BATQ01000117_gene4587	3.635e-16	87.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH3_k127_6796270_2	382464.ABSI01000013_gene1633	7.866e-205	657.0	COG2304@1|root,COG2304@2|Bacteria,46XD8@74201|Verrucomicrobia,2IVI0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
YHH3_k127_680394_0	635013.TherJR_2732	2.586e-186	601.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH3_k127_6829601_0	1353537.TP2_00585	5.071e-231	739.0	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG4625@1|root,COG4935@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria,COG4935@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,DUF4214,HemolysinCabind,Hint_2
YHH3_k127_6855827_1	316067.Geob_3064	4.248e-16	92.0	COG0823@1|root,COG1520@1|root,COG3794@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	2.4.1.109,3.2.1.4	ko:K00728,ko:K01179,ko:K13669	ko00500,ko00514,ko00515,ko01100,map00500,map00514,map00515,map01100	-	R04072,R06200,R07620,R11307,R11308,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GH5,GH9,GT39,GT87	-	CHU_C,GT87,PD40,VCBS
YHH3_k127_6855827_2	1210045.ALNP01000006_gene4879	1.136e-13	84.0	COG1409@1|root,COG1409@2|Bacteria,2GP0C@201174|Actinobacteria	201174|Actinobacteria	P	Purple acid Phosphatase, N-terminal domain	ppe2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,TAT_signal
YHH3_k127_6855827_3	1499967.BAYZ01000099_gene4398	1.509e-09	59.0	COG1943@1|root,COG1943@2|Bacteria,2NQ84@2323|unclassified Bacteria	2|Bacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
YHH3_k127_6855827_0	96561.Dole_0411	2.953e-43	160.0	COG1487@1|root,COG1487@2|Bacteria,1MZZ9@1224|Proteobacteria,42UZN@68525|delta/epsilon subdivisions,2WQ62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_686001_0	1408433.JHXV01000009_gene1333	1.359e-93	345.0	COG1520@1|root,COG3291@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,4NSXT@976|Bacteroidetes,1I7KG@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
YHH3_k127_686001_1	313595.P700755_001254	7.536e-16	87.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
YHH3_k127_6868548_1	595460.RRSWK_03838	5.99e-95	326.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	1.6.5.3,3.4.21.107	ko:K00337,ko:K04771	ko00190,ko01100,ko01503,ko02020,map00190,map01100,map01503,map02020	M00144,M00728	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	3.D.1	-	-	NADHdh,PDZ_2,Trypsin_2
YHH3_k127_6868548_2	694427.Palpr_0195	2.709e-17	86.0	COG1943@1|root,COG1943@2|Bacteria,4NPPG@976|Bacteroidetes,2FTKF@200643|Bacteroidia,23217@171551|Porphyromonadaceae	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH3_k127_6868548_0	697281.Mahau_2287	9.309e-121	398.0	COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia,42HTX@68295|Thermoanaerobacterales	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	FIVAR,Glyco_hyd_65N_2
YHH3_k127_6914407_1	234267.Acid_4012	2.325e-35	140.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6914407_0	1123277.KB893176_gene3709	1.486e-257	821.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	-	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15,SH3_3,SH3_4,VanY
YHH3_k127_6914407_2	1121011.AUCB01000026_gene2907	8.255e-05	53.0	COG5295@1|root,COG5492@1|root,COG5295@2|Bacteria,COG5492@2|Bacteria,4NTD6@976|Bacteroidetes,1I5EC@117743|Flavobacteriia,23HZS@178469|Arenibacter	976|Bacteroidetes	NUW	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6928152_5	751945.Theos_0803	9.967e-29	119.0	COG0735@1|root,COG0735@2|Bacteria,1WJYT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH3_k127_6928152_3	1118054.CAGW01000068_gene1890	8.97e-38	155.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,4H9ZX@91061|Bacilli,26QWQ@186822|Paenibacillaceae	91061|Bacilli	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
YHH3_k127_6928152_2	583355.Caka_2819	3.583e-68	236.0	COG0663@1|root,COG0663@2|Bacteria,46V13@74201|Verrucomicrobia,3K82W@414999|Opitutae	414999|Opitutae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YHH3_k127_6928152_1	497964.CfE428DRAFT_3026	1.104e-70	246.0	COG2227@1|root,COG2227@2|Bacteria,46SQK@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YHH3_k127_6928152_0	382464.ABSI01000023_gene566	2.489e-122	408.0	COG1169@1|root,COG1169@2|Bacteria,46TTI@74201|Verrucomicrobia	74201|Verrucomicrobia	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
YHH3_k127_6928152_4	794903.OPIT5_19625	5.507e-33	134.0	COG4559@1|root,COG4559@2|Bacteria,46W2C@74201|Verrucomicrobia,3K8XY@414999|Opitutae	414999|Opitutae	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
YHH3_k127_6948755_0	583355.Caka_1062	4.176e-193	608.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,3K7MH@414999|Opitutae	414999|Opitutae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YHH3_k127_6948755_1	452637.Oter_2677	2.767e-117	388.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia,3K7PV@414999|Opitutae	414999|Opitutae	H	Protein-arginine kinase	-	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
YHH3_k127_6948755_3	452637.Oter_2676	4.546e-54	195.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia,3K823@414999|Opitutae	414999|Opitutae	S	UvrB/uvrC motif	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
YHH3_k127_6948755_2	794903.OPIT5_24180	2.1e-69	238.0	COG0115@1|root,COG0115@2|Bacteria,46S9W@74201|Verrucomicrobia,3K7I4@414999|Opitutae	414999|Opitutae	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YHH3_k127_6954456_0	926550.CLDAP_29120	1.141e-45	172.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_6954456_1	1232453.BAIF02000054_gene1170	3.14e-41	166.0	COG2017@1|root,COG2017@2|Bacteria,1VGHI@1239|Firmicutes	1239|Firmicutes	G	galactose mutarotase	yoxA	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
YHH3_k127_6954456_2	1403819.BATR01000176_gene5944	2.889e-07	54.0	COG1943@1|root,COG1943@2|Bacteria,46V7I@74201|Verrucomicrobia,2IVMQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH3_k127_695608_3	1239415.CM001837_gene1236	8.448e-13	68.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1HY4A@117743|Flavobacteriia,37EW2@326319|Dokdonia	976|Bacteroidetes	J	Leucyl-tRNA synthetase, Domain 2	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
YHH3_k127_695608_1	794903.OPIT5_17990	2.066e-158	512.0	COG0265@1|root,COG0265@2|Bacteria,46X1C@74201|Verrucomicrobia,3K7EQ@414999|Opitutae	414999|Opitutae	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH3_k127_695608_2	321327.CYA_0393	3.606e-22	102.0	COG0571@1|root,COG0571@2|Bacteria,1GPDR@1117|Cyanobacteria,1H2ZG@1129|Synechococcus	1117|Cyanobacteria	K	ribonuclease III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_695608_0	768671.ThimaDRAFT_0775	8.575e-232	724.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,1RMGK@1236|Gammaproteobacteria,1WWHA@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH3_k127_6956546_0	583355.Caka_0792	2.348e-125	406.0	COG0673@1|root,COG0673@2|Bacteria,46UJR@74201|Verrucomicrobia,3K94Y@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_7006381_28	595460.RRSWK_06858	9.057e-12	67.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_7006381_7	1121904.ARBP01000024_gene6654	5.364e-155	505.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,47JKY@768503|Cytophagia	976|Bacteroidetes	P	C-terminal region of aryl-sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_7006381_29	313628.LNTAR_11951	0.0001269	48.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_7006381_0	382464.ABSI01000013_gene1541	0.0	1128.0	COG3459@1|root,COG3459@2|Bacteria,46UFY@74201|Verrucomicrobia,2IU75@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
YHH3_k127_7006381_15	1396418.BATQ01000020_gene5035	2.299e-90	324.0	COG3119@1|root,COG3119@2|Bacteria,46ZJS@74201|Verrucomicrobia,2IVBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_7006381_23	1123070.KB899251_gene727	5.119e-39	146.0	COG4115@1|root,COG4115@2|Bacteria	2|Bacteria	D	mRNA cleavage	yoeB	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
YHH3_k127_7006381_25	1123070.KB899251_gene728	7.583e-32	126.0	COG2161@1|root,COG2161@2|Bacteria,46XSV@74201|Verrucomicrobia,2IWHJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH3_k127_7006381_9	794903.OPIT5_26420	8.05e-126	410.0	COG0825@1|root,COG0825@2|Bacteria,46SE1@74201|Verrucomicrobia,3K7TK@414999|Opitutae	414999|Opitutae	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
YHH3_k127_7006381_26	794903.OPIT5_19970	2.065e-29	120.0	COG5010@1|root,COG5010@2|Bacteria,46Z5S@74201|Verrucomicrobia,3K888@414999|Opitutae	414999|Opitutae	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7006381_21	1123070.KB899251_gene803	7.25e-52	192.0	COG2940@1|root,COG2940@2|Bacteria,46W0B@74201|Verrucomicrobia,2IUGA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
YHH3_k127_7006381_14	794903.OPIT5_11785	7.909e-92	308.0	COG0708@1|root,COG0708@2|Bacteria,46TGT@74201|Verrucomicrobia,3K7VW@414999|Opitutae	414999|Opitutae	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
YHH3_k127_7006381_24	1288494.EBAPG3_170	8.018e-39	150.0	2DNU1@1|root,32Z4S@2|Bacteria,1N8FB@1224|Proteobacteria,2WG7W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
YHH3_k127_7006381_27	706587.Desti_4133	3.061e-26	117.0	28JYU@1|root,2Z9NZ@2|Bacteria,1N5J2@1224|Proteobacteria,42UJJ@68525|delta/epsilon subdivisions,2X7XY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7006381_12	448385.sce4705	3.575e-118	389.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
YHH3_k127_7006381_8	1123070.KB899251_gene657	1.486e-144	469.0	COG5557@1|root,COG5557@2|Bacteria,46U15@74201|Verrucomicrobia,2ITS8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
YHH3_k127_7006381_4	2340.JV46_09630	2.201e-194	617.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
YHH3_k127_7006381_22	583355.Caka_0069	1.919e-46	170.0	COG1959@1|root,COG1959@2|Bacteria,46VWM@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YHH3_k127_7006381_16	1333998.M2A_0142	4.708e-83	291.0	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,2U1FE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
YHH3_k127_7006381_13	649638.Trad_2887	8.166e-108	359.0	COG1063@1|root,COG1063@2|Bacteria,1WMEX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_7006381_17	583355.Caka_2877	3.813e-77	272.0	COG2706@1|root,COG2706@2|Bacteria,46SHH@74201|Verrucomicrobia,3K826@414999|Opitutae	414999|Opitutae	G	6-phosphogluconolactonase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
YHH3_k127_7006381_2	240016.ABIZ01000001_gene4830	8.507e-222	703.0	COG1132@1|root,COG1132@2|Bacteria,46UPX@74201|Verrucomicrobia,2IV95@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
YHH3_k127_7006381_1	240016.ABIZ01000001_gene4829	6.105e-248	780.0	COG1132@1|root,COG1132@2|Bacteria,46UY5@74201|Verrucomicrobia,2IV6C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
YHH3_k127_7006381_3	595460.RRSWK_04417	7.817e-216	679.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
YHH3_k127_7006381_19	583355.Caka_0713	5.946e-57	209.0	COG2207@1|root,COG2207@2|Bacteria,46V2R@74201|Verrucomicrobia,3K86B@414999|Opitutae	414999|Opitutae	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
YHH3_k127_7006381_5	234267.Acid_2859	3.997e-188	593.0	COG1063@1|root,COG1063@2|Bacteria,3Y2H8@57723|Acidobacteria	2|Bacteria	E	PFAM Alcohol dehydrogenase	yphC	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	iECW_1372.ECW_m2771,iWFL_1372.ECW_m2771	ADH_N,ADH_zinc_N
YHH3_k127_7006381_18	694427.Palpr_2280	2.941e-73	250.0	COG4154@1|root,COG4154@2|Bacteria,4NPBW@976|Bacteroidetes,2FSQ3@200643|Bacteroidia,2309J@171551|Porphyromonadaceae	976|Bacteroidetes	G	RbsD / FucU transport protein family	-	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
YHH3_k127_7006381_6	595460.RRSWK_03750	4.599e-163	518.0	COG0656@1|root,COG0656@2|Bacteria,2IWVI@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Aldo keto reductase family	-	-	1.1.1.307	ko:K17743	ko00040,ko01100,map00040,map01100	-	R01431,R09477	RC00133	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
YHH3_k127_7006381_11	382464.ABSI01000010_gene3345	3.328e-119	394.0	COG4977@1|root,COG4977@2|Bacteria,46VJD@74201|Verrucomicrobia,2IWPJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Peripla_BP_3
YHH3_k127_7006381_10	382464.ABSI01000010_gene3344	2.984e-119	394.0	COG0153@1|root,COG0153@2|Bacteria,46V7W@74201|Verrucomicrobia,2IU6C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Galactokinase galactose-binding signature	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
YHH3_k127_7006381_20	661478.OP10G_1601	1.802e-54	194.0	COG1085@1|root,COG1085@2|Bacteria	2|Bacteria	C	galactose-1-phosphate uridylyltransferase	galT	GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0842,iYL1228.KPN_00772	GalP_UDP_tr_C,GalP_UDP_transf
YHH3_k127_703643_0	575540.Isop_0635	1.168e-186	599.0	COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,2IZ24@203682|Planctomycetes	203682|Planctomycetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
YHH3_k127_703643_2	886293.Sinac_4290	5.192e-103	348.0	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
YHH3_k127_703643_1	247490.KSU1_C1622	1.249e-178	572.0	COG1730@1|root,COG1730@2|Bacteria	2|Bacteria	O	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
YHH3_k127_703643_3	583355.Caka_2409	2.834e-38	147.0	COG0496@1|root,COG0496@2|Bacteria,46VWW@74201|Verrucomicrobia,3K79M@414999|Opitutae	414999|Opitutae	S	Survival protein SurE	-	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
YHH3_k127_7043423_2	457424.BFAG_00656	7.326e-30	126.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	ko:K19429	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
YHH3_k127_7043423_1	583355.Caka_1980	1.967e-30	129.0	2B9D7@1|root,322QY@2|Bacteria,46Y12@74201|Verrucomicrobia,3K9WH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7043423_3	382464.ABSI01000010_gene3403	3.951e-27	120.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia,2IUFS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_7043423_0	313628.LNTAR_12476	1.744e-131	428.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	2.1.1.331,2.1.1.332	ko:K13601,ko:K13602	ko00860,ko01110,map00860,map01110	-	R11507,R11508,R11509	RC03457,RC03458,RC03459	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4070,Radical_SAM
YHH3_k127_707410_0	756272.Plabr_1830	8.811e-204	643.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase,YHYH
YHH3_k127_707410_2	1380600.AUYN01000009_gene1075	2.154e-80	297.0	COG5652@1|root,COG5652@2|Bacteria,4PP4C@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
YHH3_k127_707410_1	1123277.KB893206_gene3436	4.403e-135	454.0	COG1874@1|root,COG1874@2|Bacteria,4PPRG@976|Bacteroidetes	976|Bacteroidetes	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6
YHH3_k127_707410_3	63737.Npun_R0465	5.827e-38	146.0	COG5470@1|root,COG5470@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
YHH3_k127_707410_4	471870.BACINT_01575	9.256e-10	63.0	COG0457@1|root,COG0457@2|Bacteria,4NIBU@976|Bacteroidetes,2FMSC@200643|Bacteroidia,4ANAT@815|Bacteroidaceae	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107,TPR_16,TPR_6,TPR_8
YHH3_k127_7082003_2	595460.RRSWK_02095	1.842e-23	101.0	COG4146@1|root,COG4146@2|Bacteria,2J29I@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_7082003_0	595460.RRSWK_00635	1.69e-231	730.0	COG3119@1|root,COG3119@2|Bacteria,2IX47@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.10.1.1	ko:K01565	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07814	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_7082003_1	595460.RRSWK_04038	1.713e-30	123.0	COG3119@1|root,COG5434@1|root,COG3119@2|Bacteria,COG5434@2|Bacteria,2IX9T@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF4976,Glyco_hydro_28,Pectate_lyase_3,Sulfatase
YHH3_k127_7088982_16	583355.Caka_0439	3.68e-44	165.0	COG1757@1|root,COG1757@2|Bacteria	2|Bacteria	C	Na H antiporter	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
YHH3_k127_7088982_17	382464.ABSI01000012_gene2056	3.436e-25	109.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH3_k127_7088982_15	1123073.KB899241_gene3324	2.687e-59	211.0	COG0590@1|root,COG0590@2|Bacteria,1RFCW@1224|Proteobacteria,1S5YA@1236|Gammaproteobacteria,1XC1R@135614|Xanthomonadales	135614|Xanthomonadales	FJ	deaminase	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
YHH3_k127_7088982_10	583355.Caka_1355	2.184e-85	297.0	COG0654@1|root,COG0654@2|Bacteria,46VIV@74201|Verrucomicrobia	74201|Verrucomicrobia	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
YHH3_k127_7088982_0	1191523.MROS_2367	0.0	1033.0	COG3808@1|root,COG3808@2|Bacteria	2|Bacteria	C	hydrogen-translocating pyrophosphatase activity	hppA	-	3.6.1.1	ko:K01507,ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
YHH3_k127_7088982_12	765911.Thivi_3566	3.653e-76	263.0	28JYD@1|root,2Z9NN@2|Bacteria,1MV9T@1224|Proteobacteria,1S18H@1236|Gammaproteobacteria,1WWSD@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7088982_5	583355.Caka_1780	1.337e-123	421.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH3_k127_7088982_13	583355.Caka_1779	9.101e-73	261.0	COG3291@1|root,COG3291@2|Bacteria,46VB2@74201|Verrucomicrobia,3K9UE@414999|Opitutae	414999|Opitutae	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7088982_22	1408322.JHYK01000010_gene1428	0.0001577	50.0	COG0745@1|root,COG0745@2|Bacteria,1UPIZ@1239|Firmicutes,25HHI@186801|Clostridia,27N0P@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH3_k127_7088982_23	452637.Oter_4245	0.0004528	48.0	2A4RK@1|root,30TD0@2|Bacteria,46YHS@74201|Verrucomicrobia,3K9M1@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7088982_21	452637.Oter_4246	1.109e-16	93.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG3292@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,46YTG@74201|Verrucomicrobia,3K7R8@414999|Opitutae	414999|Opitutae	T	Two component regulator three Y domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg,Y_Y_Y
YHH3_k127_7088982_18	278957.ABEA03000017_gene2960	5.438e-19	91.0	COG2197@1|root,COG2197@2|Bacteria,46XU7@74201|Verrucomicrobia,3K85E@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_7088982_7	1384056.N787_03250	9.559e-101	350.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RQM3@1236|Gammaproteobacteria,1X4AK@135614|Xanthomonadales	135614|Xanthomonadales	I	Cardiolipin synthase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
YHH3_k127_7088982_4	1279009.ADICEAN_02904	1.364e-126	420.0	COG0277@1|root,COG0277@2|Bacteria,4NHFC@976|Bacteroidetes,47M51@768503|Cytophagia	976|Bacteroidetes	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,DUF805,FAD_binding_4
YHH3_k127_7088982_20	1297742.A176_04687	1.02e-17	92.0	COG0640@1|root,COG0640@2|Bacteria,1QVGE@1224|Proteobacteria	1224|Proteobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
YHH3_k127_7088982_19	583355.Caka_2267	7.48e-18	93.0	COG0810@1|root,COG0810@2|Bacteria,46WRI@74201|Verrucomicrobia,3K8HB@414999|Opitutae	414999|Opitutae	M	Biopolymer transporter TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH3_k127_7088982_9	583355.Caka_2812	4.964e-87	295.0	COG1477@1|root,COG1477@2|Bacteria,46W8K@74201|Verrucomicrobia,3K9TT@414999|Opitutae	414999|Opitutae	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
YHH3_k127_7088982_3	583355.Caka_2813	1.812e-128	427.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia,3K9I6@414999|Opitutae	414999|Opitutae	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_7088982_8	583355.Caka_2921	2.218e-99	329.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,3K9H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7088982_2	583355.Caka_2922	1.167e-183	584.0	COG0673@1|root,COG0673@2|Bacteria,46ZKA@74201|Verrucomicrobia,3K93V@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_7088982_14	583355.Caka_2923	4.242e-65	227.0	2B784@1|root,340E3@2|Bacteria,46VVJ@74201|Verrucomicrobia,3K9TS@414999|Opitutae	414999|Opitutae	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	-
YHH3_k127_7088982_6	583355.Caka_2930	1.291e-108	358.0	COG4977@1|root,COG4977@2|Bacteria,46WEY@74201|Verrucomicrobia,3K92Z@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	ko:K02854	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,PAS_4
YHH3_k127_7088982_1	583355.Caka_2932	5.345e-216	674.0	COG0673@1|root,COG0673@2|Bacteria,46TXS@74201|Verrucomicrobia,3K7RH@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_7088982_11	452637.Oter_3539	1.301e-78	270.0	COG0666@1|root,COG3828@1|root,COG0666@2|Bacteria,COG3828@2|Bacteria,46YYM@74201|Verrucomicrobia,3K9JB@414999|Opitutae	414999|Opitutae	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_709038_1	439235.Dalk_1850	5.852e-25	123.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM26,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
YHH3_k127_709038_4	1454010.JEOE01000001_gene621	4.872e-06	59.0	COG4254@1|root,COG4733@1|root,COG4254@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	FecR,fn3
YHH3_k127_709038_2	1121403.AUCV01000020_gene3093	1.443e-20	109.0	COG2755@1|root,COG4886@1|root,COG2755@2|Bacteria,COG4886@2|Bacteria,1RHDZ@1224|Proteobacteria,42SMX@68525|delta/epsilon subdivisions,2WPRJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH3_k127_709038_0	439235.Dalk_3281	7.166e-47	196.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Big_3_2,Cadherin-like,Calx-beta,DUF11,DUF4347,DUF4430,DUF915,FTP,HYR,I-set,PQQ_2,PT-HINT,Peptidase_M36,Pro-kuma_activ,RHS_repeat,VCBS
YHH3_k127_7092211_0	56107.Cylst_5848	7.203e-13	71.0	COG2337@1|root,COG2337@2|Bacteria,1GIQZ@1117|Cyanobacteria,1HPA0@1161|Nostocales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH3_k127_7092211_1	583355.Caka_2226	8.347e-11	72.0	COG2165@1|root,COG2165@2|Bacteria,46TPU@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7092211_2	1500897.JQNA01000002_gene4649	2.243e-06	59.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,1K62V@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
YHH3_k127_7093505_4	700598.Niako_1946	3.562e-06	53.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,1ISIU@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
YHH3_k127_7093505_1	1142394.PSMK_04760	2.09e-21	104.0	2FGJC@1|root,348F6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
YHH3_k127_7093505_0	87626.PTD2_00666	3.183e-26	125.0	COG3266@1|root,COG4932@1|root,COG5183@1|root,COG3266@2|Bacteria,COG4932@2|Bacteria,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,2Q2R1@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	A	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8,TSP_3
YHH3_k127_7093505_3	1142394.PSMK_04760	3.778e-17	91.0	2FGJC@1|root,348F6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
YHH3_k127_7093505_2	1142394.PSMK_04760	1.837e-17	92.0	2FGJC@1|root,348F6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
YHH3_k127_7094462_5	765869.BDW_05105	5.419e-07	54.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2MT35@213481|Bdellovibrionales,2WJFA@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
YHH3_k127_7094462_1	583355.Caka_2415	1.144e-86	298.0	COG0373@1|root,COG0373@2|Bacteria,46SMQ@74201|Verrucomicrobia,3K7CJ@414999|Opitutae	414999|Opitutae	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,Shikimate_DH
YHH3_k127_7094462_3	583355.Caka_2416	5.073e-49	186.0	COG4137@1|root,COG4137@2|Bacteria,46V7V@74201|Verrucomicrobia,3K7TH@414999|Opitutae	414999|Opitutae	S	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
YHH3_k127_7094462_0	382464.ABSI01000005_gene1230	3.344e-120	395.0	COG0276@1|root,COG0276@2|Bacteria,46XCA@74201|Verrucomicrobia,2IVEM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Ferrochelatase	-	-	-	-	-	-	-	-	-	-	-	-	Ferrochelatase
YHH3_k127_7094462_2	1519464.HY22_07420	3.764e-61	223.0	COG3380@1|root,COG3380@2|Bacteria	2|Bacteria	S	monoamine oxidase activity	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
YHH3_k127_7094462_4	746697.Aeqsu_0488	6.579e-08	54.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes,1I0GI@117743|Flavobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
YHH3_k127_7098521_2	316273.XCV4085	1.003e-21	104.0	COG3828@1|root,COG3828@2|Bacteria,1RATT@1224|Proteobacteria,1RRU8@1236|Gammaproteobacteria,1XABU@135614|Xanthomonadales	135614|Xanthomonadales	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
YHH3_k127_7098521_0	1121904.ARBP01000013_gene349	1.221e-68	236.0	COG4948@1|root,COG4948@2|Bacteria,4NKNN@976|Bacteroidetes,47JKW@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
YHH3_k127_7116830_1	518766.Rmar_2391	1.507e-177	569.0	COG5434@1|root,COG5434@2|Bacteria,4NEM8@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Glyco_hydro_88,Pectate_lyase_3
YHH3_k127_7116830_0	1288963.ADIS_1244	1.061e-211	671.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_7116830_2	314230.DSM3645_18316	3.848e-49	183.0	COG3119@1|root,COG3119@2|Bacteria,2IXXP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_7136298_0	278957.ABEA03000075_gene2315	1.253e-124	417.0	COG1132@1|root,COG1132@2|Bacteria,46S6K@74201|Verrucomicrobia,3K7CG@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
YHH3_k127_7136298_2	883.DvMF_2965	2.754e-25	113.0	COG3133@1|root,COG3133@2|Bacteria,1RA1D@1224|Proteobacteria,42TU5@68525|delta/epsilon subdivisions,2WQHI@28221|Deltaproteobacteria,2MCVB@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycine zipper 2TM domain	-	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
YHH3_k127_7136298_1	756272.Plabr_3854	7.06e-73	253.0	COG1028@1|root,COG1028@2|Bacteria	756272.Plabr_3854|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7136298_3	694427.Palpr_2588	4.304e-14	83.0	COG5015@1|root,COG5015@2|Bacteria,4P5J8@976|Bacteroidetes,2FW0K@200643|Bacteroidia	976|Bacteroidetes	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
YHH3_k127_7151329_1	794903.OPIT5_15220	3.716e-52	192.0	COG0304@1|root,COG0304@2|Bacteria,46UQ4@74201|Verrucomicrobia,3K78C@414999|Opitutae	414999|Opitutae	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH3_k127_7151329_2	382464.ABSI01000011_gene2555	6.2e-10	64.0	COG0236@1|root,COG0764@1|root,COG0236@2|Bacteria,COG0764@2|Bacteria,46UWI@74201|Verrucomicrobia	74201|Verrucomicrobia	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA
YHH3_k127_7151329_0	679935.Alfi_1545	2.068e-93	323.0	COG1032@1|root,COG1032@2|Bacteria,4NKFV@976|Bacteroidetes	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YHH3_k127_7163833_1	583355.Caka_1897	1.06e-121	395.0	COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,3K7B5@414999|Opitutae	414999|Opitutae	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_7163833_6	452637.Oter_2838	8.131e-49	179.0	COG1522@1|root,COG1522@2|Bacteria,46VIJ@74201|Verrucomicrobia,3K7WN@414999|Opitutae	414999|Opitutae	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
YHH3_k127_7163833_5	452637.Oter_3784	3.354e-74	263.0	COG1565@1|root,COG1565@2|Bacteria,46T7F@74201|Verrucomicrobia,3K7JD@414999|Opitutae	414999|Opitutae	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
YHH3_k127_7163833_8	382464.ABSI01000010_gene3843	9.016e-28	113.0	COG0227@1|root,COG0227@2|Bacteria,46TBF@74201|Verrucomicrobia,2IUUU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
YHH3_k127_7163833_4	583355.Caka_1139	2.158e-77	267.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia,3K7JY@414999|Opitutae	414999|Opitutae	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
YHH3_k127_7163833_2	794903.OPIT5_10670	2.382e-97	327.0	COG0175@1|root,COG0175@2|Bacteria,46U3C@74201|Verrucomicrobia,3K7TU@414999|Opitutae	414999|Opitutae	C	Phosphoadenosine phosphosulfate reductase	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YHH3_k127_7163833_0	382464.ABSI01000010_gene3779	1.031e-213	683.0	COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia,2ITPR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	-	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YHH3_k127_7163833_9	382464.ABSI01000010_gene3780	4.383e-14	79.0	COG5652@1|root,COG5652@2|Bacteria,46WK5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
YHH3_k127_7163833_3	452637.Oter_4016	1.984e-85	291.0	COG0236@1|root,COG0764@1|root,COG0236@2|Bacteria,COG0764@2|Bacteria,46XU4@74201|Verrucomicrobia,3K848@414999|Opitutae	414999|Opitutae	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
YHH3_k127_7163833_7	794903.OPIT5_15220	7.801e-37	144.0	COG0304@1|root,COG0304@2|Bacteria,46UQ4@74201|Verrucomicrobia,3K78C@414999|Opitutae	414999|Opitutae	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH3_k127_7172193_0	452637.Oter_1545	3.701e-178	572.0	COG1894@1|root,COG3411@1|root,COG1894@2|Bacteria,COG3411@2|Bacteria,46S8J@74201|Verrucomicrobia,3K7HM@414999|Opitutae	2|Bacteria	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	hoxF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K05587,ko:K17992,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
YHH3_k127_7172193_1	452637.Oter_1546	1.572e-66	231.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YHH3_k127_7172193_2	314231.FP2506_04336	1.521e-21	97.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,2PK80@255475|Aurantimonadaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	nolR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22042	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
YHH3_k127_7172193_3	1123253.AUBD01000004_gene1061	1.53e-20	93.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,1X8IF@135614|Xanthomonadales	135614|Xanthomonadales	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
YHH3_k127_7172193_4	1121396.KB893066_gene1578	3.64e-15	82.0	COG1538@1|root,COG1538@2|Bacteria,1R8XP@1224|Proteobacteria,42QGI@68525|delta/epsilon subdivisions,2WJH9@28221|Deltaproteobacteria,2MJD1@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_7203111_0	452637.Oter_0894	0.0	1174.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,46U9T@74201|Verrucomicrobia,3K7GP@414999|Opitutae	414999|Opitutae	E	glutamate synthase	-	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
YHH3_k127_7203111_1	56110.Oscil6304_3495	5.276e-182	578.0	COG0493@1|root,COG0493@2|Bacteria,1G0SD@1117|Cyanobacteria,1H8CN@1150|Oscillatoriales	1117|Cyanobacteria	E	TIGRFAM glutamate synthases, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD	Fer4_20,Pyr_redox_2
YHH3_k127_7238101_1	349741.Amuc_0806	1.198e-32	139.0	COG0168@1|root,COG0168@2|Bacteria,46U92@74201|Verrucomicrobia,2IVH0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
YHH3_k127_7238101_0	1396418.BATQ01000175_gene2797	2.348e-65	231.0	COG0745@1|root,COG0745@2|Bacteria,46UC4@74201|Verrucomicrobia,2IUBT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH3_k127_7238101_2	1397528.Q671_04035	5.923e-08	55.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XHAU@135619|Oceanospirillales	135619|Oceanospirillales	T	Signal transduction histidine kinase	-	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9,dCache_1
YHH3_k127_7260362_2	991.IW20_08295	4.163e-13	80.0	COG2207@1|root,COG2207@2|Bacteria,4NMWI@976|Bacteroidetes,1IIKZ@117743|Flavobacteriia,2NUJV@237|Flavobacterium	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
YHH3_k127_7260362_1	1396141.BATP01000004_gene5915	4.02e-21	104.0	COG1414@1|root,COG1414@2|Bacteria,46VJM@74201|Verrucomicrobia,2IVTQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
YHH3_k127_7260362_0	1121904.ARBP01000008_gene3301	2.439e-117	386.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,47J9W@768503|Cytophagia	976|Bacteroidetes	EG	PFAM RhaT l-rhamnose-proton symport 2	-	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
YHH3_k127_7287227_1	1237149.C900_02883	1.636e-32	132.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,47JIP@768503|Cytophagia	976|Bacteroidetes	P	PFAM Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
YHH3_k127_7287227_0	760192.Halhy_1427	3.323e-41	160.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,1IPNR@117747|Sphingobacteriia	976|Bacteroidetes	P	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
YHH3_k127_7308323_4	452637.Oter_2641	1.308e-44	169.0	COG0206@1|root,COG0206@2|Bacteria,46UAJ@74201|Verrucomicrobia,3K7KG@414999|Opitutae	414999|Opitutae	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YHH3_k127_7308323_1	1333507.AUTQ01000248_gene2211	2.5e-96	338.0	COG1629@1|root,COG4771@2|Bacteria,1MUF1@1224|Proteobacteria,1RQF8@1236|Gammaproteobacteria,2Q0DE@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
YHH3_k127_7308323_2	926569.ANT_10750	1.514e-55	205.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yigM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
YHH3_k127_7308323_3	862908.BMS_0944	6.759e-51	188.0	COG0349@1|root,COG0349@2|Bacteria,1REMB@1224|Proteobacteria,42S18@68525|delta/epsilon subdivisions,2WN9J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
YHH3_k127_7308323_7	583355.Caka_2410	9.498e-20	94.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
YHH3_k127_7308323_0	583355.Caka_2338	1.211e-203	661.0	COG0553@1|root,COG0553@2|Bacteria,46UW7@74201|Verrucomicrobia,3K7NY@414999|Opitutae	414999|Opitutae	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH3_k127_7308323_6	583355.Caka_1563	1.911e-34	141.0	COG0631@1|root,COG0631@2|Bacteria,46ZFD@74201|Verrucomicrobia,3K84Y@414999|Opitutae	414999|Opitutae	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
YHH3_k127_7308323_5	452637.Oter_3486	1.785e-43	160.0	COG1199@1|root,COG1199@2|Bacteria,46SCS@74201|Verrucomicrobia,3K7G8@414999|Opitutae	414999|Opitutae	KL	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2
YHH3_k127_7313310_0	926550.CLDAP_19940	2.13e-273	859.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_7313310_1	452637.Oter_0633	5.015e-171	548.0	COG0114@1|root,COG0114@2|Bacteria,46SFC@74201|Verrucomicrobia,3K7NN@414999|Opitutae	414999|Opitutae	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
YHH3_k127_7313310_2	756272.Plabr_3214	5.48e-113	372.0	COG3119@1|root,COG3119@2|Bacteria,2J1W6@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_7345349_3	497964.CfE428DRAFT_2852	1.55e-32	137.0	2BZ98@1|root,2ZRHF@2|Bacteria,46WMB@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7345349_0	497964.CfE428DRAFT_2853	1.334e-136	448.0	COG3522@1|root,COG3522@2|Bacteria,46UPG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VasE
YHH3_k127_7345349_2	497964.CfE428DRAFT_2854	7.175e-39	154.0	2DXSN@1|root,346BX@2|Bacteria,46W22@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Type VI secretion system protein DotU	-	-	-	-	-	-	-	-	-	-	-	-	DotU
YHH3_k127_7345349_1	1396141.BATP01000024_gene782	2.231e-85	297.0	COG3523@1|root,COG3523@2|Bacteria,46VI0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ImcF-related N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ImcF-related_N
YHH3_k127_7385460_2	1122214.AQWH01000002_gene4159	2.563e-40	156.0	COG0673@1|root,COG0673@2|Bacteria,1PHFG@1224|Proteobacteria,2V8DX@28211|Alphaproteobacteria,2PMAY@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_7385460_0	1122137.AQXF01000004_gene1524	1.462e-93	323.0	COG0477@1|root,COG2814@2|Bacteria,1QWEI@1224|Proteobacteria,2U6BP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
YHH3_k127_7385460_1	530564.Psta_4579	2.086e-76	261.0	COG0673@1|root,COG0673@2|Bacteria,2IXDR@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_7388201_1	637905.SVI_1093	2.673e-28	134.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,1PFWN@1224|Proteobacteria,1SX3N@1236|Gammaproteobacteria,2QDG6@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,fn3
YHH3_k127_7388201_0	2850.Phatr44695	1.557e-117	413.0	2BP9V@1|root,2S1RF@2759|Eukaryota,2XBPA@2836|Bacillariophyta	2836|Bacillariophyta	O	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6,SdrD_B
YHH3_k127_7393644_0	583355.Caka_2669	6.154e-297	928.0	COG1185@1|root,COG1185@2|Bacteria,46SBP@74201|Verrucomicrobia,3K7BU@414999|Opitutae	414999|Opitutae	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YHH3_k127_7393644_4	794903.OPIT5_01100	2.619e-30	125.0	COG0184@1|root,COG0184@2|Bacteria,46T87@74201|Verrucomicrobia,3K894@414999|Opitutae	414999|Opitutae	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
YHH3_k127_7393644_3	382464.ABSI01000001_gene4228	1.505e-85	290.0	COG0327@1|root,COG0327@2|Bacteria,46U7Z@74201|Verrucomicrobia,2IU4W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
YHH3_k127_7393644_1	999541.bgla_1g11520	1.904e-152	494.0	COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,2VP16@28216|Betaproteobacteria,1K0AZ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)	astB	-	3.5.3.23	ko:K01484	ko00330,ko01100,map00330,map01100	-	R04189	RC00024	ko00000,ko00001,ko01000	-	-	-	AstB
YHH3_k127_7393644_2	382464.ABSI01000005_gene1020	3.108e-96	318.0	COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,2ITQ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	LeuA allosteric (dimerisation) domain	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
YHH3_k127_7432781_5	879212.DespoDRAFT_02042	7.31e-06	51.0	2EIZA@1|root,33CQH@2|Bacteria,1NJDM@1224|Proteobacteria,42WT9@68525|delta/epsilon subdivisions,2WT1N@28221|Deltaproteobacteria,2MMAE@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_19
YHH3_k127_7432781_4	452637.Oter_4040	1.384e-17	87.0	COG3784@1|root,COG3784@2|Bacteria,46WPU@74201|Verrucomicrobia,3K8CB@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1318)	-	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
YHH3_k127_7432781_3	583355.Caka_2567	8.392e-28	115.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH3_k127_7432781_2	583355.Caka_1274	3.114e-31	124.0	COG0211@1|root,COG0211@2|Bacteria,46X4Y@74201|Verrucomicrobia,3K8A7@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YHH3_k127_7432781_1	583355.Caka_1273	9.999e-39	147.0	COG0261@1|root,COG0261@2|Bacteria,46VNZ@74201|Verrucomicrobia,3K87S@414999|Opitutae	414999|Opitutae	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
YHH3_k127_7432781_0	452637.Oter_0500	1.341e-53	199.0	COG0169@1|root,COG0169@2|Bacteria,46SVF@74201|Verrucomicrobia,3K7SU@414999|Opitutae	414999|Opitutae	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
YHH3_k127_7434993_3	1191523.MROS_0411	4.843e-27	115.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH3_k127_7434993_2	1157708.KB907457_gene2711	6.47e-93	316.0	COG1172@1|root,COG1172@2|Bacteria,1R4R3@1224|Proteobacteria,2VJTQ@28216|Betaproteobacteria,4ACW1@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
YHH3_k127_7434993_0	756272.Plabr_3160	1.698e-133	442.0	COG1129@1|root,COG1129@2|Bacteria,2J20W@203682|Planctomycetes	203682|Planctomycetes	G	COG1129 ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
YHH3_k127_7434993_1	756272.Plabr_3159	2.261e-98	331.0	COG1879@1|root,COG1879@2|Bacteria,2J2R0@203682|Planctomycetes	203682|Planctomycetes	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
YHH3_k127_7447128_2	143224.JQMD01000002_gene181	5.469e-61	214.0	COG0823@1|root,COG0823@2|Bacteria,4NM2C@976|Bacteroidetes,1I7Q6@117743|Flavobacteriia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7447128_1	1328313.DS2_10858	4.032e-94	323.0	2B4BG@1|root,31X2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7447128_0	1396141.BATP01000007_gene5648	7.051e-174	561.0	COG1012@1|root,COG1012@2|Bacteria,46SIA@74201|Verrucomicrobia,2IU6F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
YHH3_k127_7453873_3	583355.Caka_2291	4.312e-21	93.0	COG2165@1|root,COG2165@2|Bacteria,46XVX@74201|Verrucomicrobia,3K8F0@414999|Opitutae	414999|Opitutae	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH3_k127_7453873_0	452637.Oter_2116	6.833e-127	414.0	COG4956@1|root,COG4956@2|Bacteria,46TFJ@74201|Verrucomicrobia,3K8ZF@414999|Opitutae	414999|Opitutae	S	SMART Nucleotide binding protein PINc	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7453873_1	382464.ABSI01000016_gene688	2.727e-38	160.0	COG4942@1|root,COG4942@2|Bacteria,46U5A@74201|Verrucomicrobia	74201|Verrucomicrobia	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7453873_2	583355.Caka_0906	1.379e-37	149.0	2EWFD@1|root,33PTV@2|Bacteria,46UNG@74201|Verrucomicrobia,3K7NI@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7458647_0	497964.CfE428DRAFT_5005	4.662e-87	304.0	COG2202@1|root,COG2208@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,COG5002@2|Bacteria,46U96@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_3,PAS_4,SpoIIE
YHH3_k127_7458647_1	794903.OPIT5_30540	1.336e-10	73.0	COG5074@1|root,COG5074@2|Bacteria,46XTA@74201|Verrucomicrobia,3K7YA@414999|Opitutae	414999|Opitutae	U	SNAP receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7488148_0	335543.Sfum_3546	0.0	1116.0	COG1216@1|root,COG3250@1|root,COG1216@2|Bacteria,COG3250@2|Bacteria,1R42U@1224|Proteobacteria,42UMM@68525|delta/epsilon subdivisions,2WQVW@28221|Deltaproteobacteria,2MS0N@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
YHH3_k127_7488148_1	335543.Sfum_3109	1.838e-115	382.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1N17V@1224|Proteobacteria,42PVC@68525|delta/epsilon subdivisions,2WKU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YHH3_k127_7503766_0	1122605.KB893632_gene4328	1.117e-103	338.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1IP9I@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
YHH3_k127_7503766_1	285535.JOEY01000015_gene4244	1.396e-10	76.0	COG4733@1|root,COG4733@2|Bacteria,2I3EM@201174|Actinobacteria	201174|Actinobacteria	G	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,He_PIG
YHH3_k127_7503766_2	644282.Deba_1334	0.0001011	56.0	COG4412@1|root,COG4412@2|Bacteria,1RKAD@1224|Proteobacteria,43ARU@68525|delta/epsilon subdivisions,2X65X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
YHH3_k127_7515853_1	869213.JCM21142_42034	1.149e-109	374.0	COG4625@1|root,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
YHH3_k127_7515853_0	595460.RRSWK_03845	8.749e-168	540.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_7532479_1	1294142.CINTURNW_0632	6.813e-41	175.0	COG2340@1|root,COG4733@1|root,COG2340@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CAP,CW_binding_2,DUF1080,SLH
YHH3_k127_7532479_0	1121396.KB892900_gene2129	3.61e-95	347.0	COG1657@1|root,COG2374@1|root,COG2931@1|root,COG3291@1|root,COG4733@1|root,COG4932@1|root,COG5306@1|root,COG1657@2|Bacteria,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,COG5306@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
YHH3_k127_7532479_3	879212.DespoDRAFT_02522	5.815e-06	60.0	COG3291@1|root,COG4870@1|root,COG3291@2|Bacteria,COG4870@2|Bacteria,1N8Z7@1224|Proteobacteria,43AX0@68525|delta/epsilon subdivisions,2X6B7@28221|Deltaproteobacteria,2MPH8@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_C1
YHH3_k127_7532479_2	96561.Dole_2766	1.186e-24	122.0	COG3420@1|root,COG3420@2|Bacteria,1NGNA@1224|Proteobacteria,43156@68525|delta/epsilon subdivisions,2WW9W@28221|Deltaproteobacteria,2MNX1@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH3_k127_7551155_0	452637.Oter_2975	6.673e-132	433.0	COG0673@1|root,COG0673@2|Bacteria,46UJ9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_7551155_1	1499967.BAYZ01000010_gene5201	4.386e-118	388.0	COG0407@1|root,COG0407@2|Bacteria,2NP39@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH3_k127_7551155_2	583355.Caka_0356	2.709e-54	198.0	COG3894@1|root,COG3894@2|Bacteria,46VH9@74201|Verrucomicrobia,3K8AT@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445
YHH3_k127_7556075_0	1265503.KB905165_gene1284	9.413e-159	516.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,He_PIG,HemolysinCabind
YHH3_k127_7556075_1	1403819.BATR01000093_gene2873	8.7e-43	164.0	COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia,2ITZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_7566200_2	382464.ABSI01000010_gene3335	2.378e-61	220.0	COG1075@1|root,COG1075@2|Bacteria,46XK0@74201|Verrucomicrobia,2IW41@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7566200_3	391603.FBALC1_08228	1.583e-50	190.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73	ko:K00852,ko:K00856,ko:K10710,ko:K22026	ko00030,ko00230,ko00240,ko01100,map00030,map00230,map00240,map01100	-	R00185,R00513,R01051,R01131,R01228,R02750,R08124	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH3_k127_7566200_1	762968.HMPREF9441_00428	1.545e-84	288.0	COG2996@1|root,COG2996@2|Bacteria,4NGS6@976|Bacteroidetes,2FP01@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	yitL	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
YHH3_k127_7566200_0	583355.Caka_2426	0.0	1380.0	COG0587@1|root,COG0587@2|Bacteria,46SG0@74201|Verrucomicrobia,3K7QJ@414999|Opitutae	414999|Opitutae	L	DNA polymerase alpha chain like domain	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
YHH3_k127_7566200_4	583355.Caka_2425	2.177e-33	139.0	2A15Q@1|root,30PBN@2|Bacteria,46XUZ@74201|Verrucomicrobia,3K8C5@414999|Opitutae	414999|Opitutae	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
YHH3_k127_7570450_2	1191523.MROS_2634	2.305e-34	136.0	2B7NJ@1|root,32VIJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7570450_1	452637.Oter_3025	6.663e-95	319.0	COG0684@1|root,COG0684@2|Bacteria,46VAD@74201|Verrucomicrobia,3K8HM@414999|Opitutae	414999|Opitutae	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
YHH3_k127_7570450_0	1499967.BAYZ01000104_gene3693	2.279e-161	523.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YHH3_k127_757721_1	595460.RRSWK_04038	3.985e-62	216.0	COG3119@1|root,COG5434@1|root,COG3119@2|Bacteria,COG5434@2|Bacteria,2IX9T@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF4976,Glyco_hydro_28,Pectate_lyase_3,Sulfatase
YHH3_k127_757721_0	760192.Halhy_0495	1.311e-78	272.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
YHH3_k127_757721_2	1382356.JQMP01000001_gene964	5.833e-49	184.0	COG4948@1|root,COG4948@2|Bacteria,2G69R@200795|Chloroflexi,27YY3@189775|Thermomicrobia	189775|Thermomicrobia	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YHH3_k127_7598116_0	1396418.BATQ01000179_gene3142	4.381e-177	595.0	COG1345@1|root,COG1404@1|root,COG1345@2|Bacteria,COG1404@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8
YHH3_k127_7600654_0	1396141.BATP01000022_gene333	0.0	1979.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7600654_1	215803.DB30_6281	3.901e-30	141.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria,2YZ03@29|Myxococcales	28221|Deltaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,REJ
YHH3_k127_7601439_9	880073.Calab_3098	7.827e-37	158.0	COG2755@1|root,COG2755@2|Bacteria,2NQ5Y@2323|unclassified Bacteria	2|Bacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	Lipase_GDSL_2
YHH3_k127_7601439_7	1166018.FAES_2962	1.077e-56	218.0	COG3386@1|root,COG3386@2|Bacteria,4NJKD@976|Bacteroidetes,47PXA@768503|Cytophagia	976|Bacteroidetes	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
YHH3_k127_7601439_8	240016.ABIZ01000001_gene3826	4.632e-50	194.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH3_k127_7601439_0	583355.Caka_1503	1.051e-285	884.0	COG0539@1|root,COG0539@2|Bacteria,46SFY@74201|Verrucomicrobia,3K7E8@414999|Opitutae	414999|Opitutae	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
YHH3_k127_7601439_10	1123248.KB893385_gene4785	1.562e-30	126.0	COG0454@1|root,COG0456@2|Bacteria,4NWTW@976|Bacteroidetes,1IZJT@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
YHH3_k127_7601439_4	583355.Caka_2568	2.358e-92	305.0	COG0377@1|root,COG0377@2|Bacteria,46U0Z@74201|Verrucomicrobia,3K7X8@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YHH3_k127_7601439_5	452637.Oter_0484	7.001e-61	218.0	COG0852@1|root,COG0852@2|Bacteria,46STM@74201|Verrucomicrobia,3K7SH@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
YHH3_k127_7601439_2	583355.Caka_2570	3.195e-208	653.0	COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,3K7QV@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
YHH3_k127_7601439_6	382464.ABSI01000016_gene645	2.179e-58	207.0	COG1905@1|root,COG1905@2|Bacteria,46VMZ@74201|Verrucomicrobia,2IU8F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YHH3_k127_7601439_1	583355.Caka_2572	2.458e-217	683.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia,3K7HM@414999|Opitutae	414999|Opitutae	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
YHH3_k127_7601439_3	382464.ABSI01000016_gene647	8.441e-99	325.0	COG1034@1|root,COG1034@2|Bacteria,46S6S@74201|Verrucomicrobia,2ITJ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
YHH3_k127_7606692_1	1122925.KB895384_gene3233	3.703e-09	63.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,26RI4@186822|Paenibacillaceae	91061|Bacilli	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,PT-TG,RHS_repeat
YHH3_k127_7606692_0	439235.Dalk_1474	3.16e-156	507.0	COG0823@1|root,COG0823@2|Bacteria,1PFY8@1224|Proteobacteria,437BT@68525|delta/epsilon subdivisions,2WURP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7614127_1	452637.Oter_3506	7.183e-53	201.0	COG0553@1|root,COG0553@2|Bacteria,46TSJ@74201|Verrucomicrobia,3K74S@414999|Opitutae	414999|Opitutae	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH3_k127_7614127_0	583355.Caka_1947	5.936e-94	319.0	COG0604@1|root,COG0604@2|Bacteria,46VV3@74201|Verrucomicrobia,3K9E2@414999|Opitutae	414999|Opitutae	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_7626345_2	926556.Echvi_2707	1.518e-149	478.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,47KSM@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_7626345_3	382464.ABSI01000010_gene3450	6.747e-139	457.0	COG0277@1|root,COG0277@2|Bacteria,46SFA@74201|Verrucomicrobia,2ITGW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YHH3_k127_7626345_8	583355.Caka_1647	2.323e-51	184.0	COG0105@1|root,COG0105@2|Bacteria,46T8K@74201|Verrucomicrobia,3K85A@414999|Opitutae	414999|Opitutae	F	Nucleoside diphosphate kinase	-	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YHH3_k127_7626345_5	1449337.JQLL01000001_gene1481	8.904e-78	276.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,4HG1X@91061|Bacilli,27I10@186828|Carnobacteriaceae	91061|Bacilli	I	YgbB family	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
YHH3_k127_7626345_7	794903.OPIT5_14920	1.312e-56	208.0	COG1947@1|root,COG1947@2|Bacteria,46SV6@74201|Verrucomicrobia,3K807@414999|Opitutae	414999|Opitutae	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YHH3_k127_7626345_1	452637.Oter_2443	7.819e-172	557.0	COG1080@1|root,COG1080@2|Bacteria,46TX4@74201|Verrucomicrobia,3K7JG@414999|Opitutae	414999|Opitutae	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
YHH3_k127_7626345_4	583355.Caka_1376	1.048e-123	403.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46UY4@74201|Verrucomicrobia,3K7AN@414999|Opitutae	414999|Opitutae	K	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
YHH3_k127_7626345_0	583355.Caka_2613	9.069e-224	709.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia,3K7NE@414999|Opitutae	414999|Opitutae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
YHH3_k127_7626345_6	583355.Caka_2612	3.775e-74	265.0	COG0144@1|root,COG0144@2|Bacteria,46V5S@74201|Verrucomicrobia,3K7YH@414999|Opitutae	414999|Opitutae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
YHH3_k127_7636729_0	794903.OPIT5_05405	1.454e-141	458.0	COG4198@1|root,COG4198@2|Bacteria,46S83@74201|Verrucomicrobia,3K7UU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
YHH3_k127_7636729_1	522306.CAP2UW1_4251	3.64e-32	129.0	2EBIG@1|root,335IZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7636729_2	522306.CAP2UW1_4252	3.337e-27	112.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2VXAW@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YHH3_k127_7654122_7	931276.Cspa_c22460	1.79e-26	117.0	COG1262@1|root,COG1262@2|Bacteria,1V03B@1239|Firmicutes,249WZ@186801|Clostridia,36E2K@31979|Clostridiaceae	186801|Clostridia	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
YHH3_k127_7654122_6	1131269.AQVV01000032_gene304	4.406e-29	120.0	2DCXT@1|root,2ZFR8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7654122_4	1408473.JHXO01000006_gene1375	1.275e-92	316.0	COG1735@1|root,COG1735@2|Bacteria,4NJYF@976|Bacteroidetes	976|Bacteroidetes	S	Phosphotriesterase family	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
YHH3_k127_7654122_1	583355.Caka_1430	8.289e-183	582.0	COG0282@1|root,COG0282@2|Bacteria,46TZF@74201|Verrucomicrobia,3K7U1@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
YHH3_k127_7654122_0	1216966.BAUC01000005_gene1955	5.803e-223	712.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,1RMJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the CobB CobQ family	pta	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006091,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008959,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015980,GO:0016053,GO:0016054,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017000,GO:0017001,GO:0017144,GO:0018130,GO:0019413,GO:0019427,GO:0019438,GO:0019541,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046394,GO:0046395,GO:0046459,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070689,GO:0071616,GO:0071704,GO:0072329,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_2834,iYL1228.KPN_02688	AAA_26,DRTGG,PTA_PTB
YHH3_k127_7654122_8	583355.Caka_2978	1.398e-12	71.0	COG0291@1|root,COG0291@2|Bacteria,46TCI@74201|Verrucomicrobia,3K8DB@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
YHH3_k127_7654122_5	583355.Caka_2979	3.097e-39	149.0	COG0292@1|root,COG0292@2|Bacteria,46SZW@74201|Verrucomicrobia,3K87I@414999|Opitutae	414999|Opitutae	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
YHH3_k127_7654122_2	382464.ABSI01000023_gene556	4.594e-149	479.0	COG0016@1|root,COG0016@2|Bacteria,46S6R@74201|Verrucomicrobia,2ITTX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YHH3_k127_7654122_3	583355.Caka_1413	1.502e-107	355.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,46SDG@74201|Verrucomicrobia,3K7G2@414999|Opitutae	414999|Opitutae	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
YHH3_k127_7656403_1	246194.CHY_1853	6.363e-14	78.0	COG5557@1|root,COG5557@2|Bacteria,1V4C0@1239|Firmicutes,24NSE@186801|Clostridia	186801|Clostridia	C	Formate-dependent nitrite reductase, membrane component	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
YHH3_k127_7656403_0	290397.Adeh_2002	1.345e-84	293.0	COG3005@1|root,COG3005@2|Bacteria,1QYG3@1224|Proteobacteria,43CC8@68525|delta/epsilon subdivisions,2X7N4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YHH3_k127_7656403_2	926569.ANT_26970	0.0002003	45.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
YHH3_k127_7659944_1	452637.Oter_2851	8.251e-155	509.0	COG1450@1|root,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,3K7FR@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
YHH3_k127_7659944_4	278957.ABEA03000050_gene160	1.419e-56	202.0	COG1051@1|root,COG1051@2|Bacteria,46V5B@74201|Verrucomicrobia,3K7WB@414999|Opitutae	414999|Opitutae	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YHH3_k127_7659944_2	1396418.BATQ01000001_gene1299	2.103e-150	484.0	COG1071@1|root,COG1071@2|Bacteria,46S69@74201|Verrucomicrobia,2ITVF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Transketolase, thiamine diphosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh
YHH3_k127_7659944_0	382464.ABSI01000005_gene1029	6.061e-156	499.0	COG0022@1|root,COG0022@2|Bacteria,46S75@74201|Verrucomicrobia,2ITIV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
YHH3_k127_7659944_3	382464.ABSI01000005_gene1028	4.998e-132	434.0	COG0508@1|root,COG0508@2|Bacteria,46SHZ@74201|Verrucomicrobia,2IU2H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	e3 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YHH3_k127_7659944_5	382464.ABSI01000011_gene2592	1.835e-06	49.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
YHH3_k127_7678412_0	278957.ABEA03000174_gene3435	7.039e-134	437.0	COG0553@1|root,COG0553@2|Bacteria,46TSJ@74201|Verrucomicrobia,3K74S@414999|Opitutae	414999|Opitutae	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH3_k127_7678412_2	583355.Caka_0245	4.033e-95	324.0	COG0795@1|root,COG0795@2|Bacteria,46T0M@74201|Verrucomicrobia,3K73D@414999|Opitutae	414999|Opitutae	S	PFAM permease YjgP YjgQ family protein	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
YHH3_k127_7678412_1	452637.Oter_2702	4.384e-108	366.0	COG1092@1|root,COG1092@2|Bacteria,46SJ5@74201|Verrucomicrobia,3K84I@414999|Opitutae	414999|Opitutae	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
YHH3_k127_7681917_2	521674.Plim_2370	3.57e-31	136.0	COG1538@1|root,COG1538@2|Bacteria,2IWU5@203682|Planctomycetes	203682|Planctomycetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_7681917_1	583355.Caka_2256	7.651e-98	331.0	COG3746@1|root,COG3746@2|Bacteria,46T78@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
YHH3_k127_7681917_0	313628.LNTAR_17358	3.494e-127	413.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
YHH3_k127_7681917_3	521719.ATXQ01000010_gene60	0.0005206	47.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1YCX5@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YHH3_k127_7685876_10	583355.Caka_2810	5.708e-83	277.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia,3K7KT@414999|Opitutae	414999|Opitutae	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
YHH3_k127_7685876_11	448385.sce0085	1.605e-77	264.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42QN7@68525|delta/epsilon subdivisions,2WP27@28221|Deltaproteobacteria,2YVXG@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
YHH3_k127_7685876_15	583355.Caka_1361	1.491e-53	194.0	COG0811@1|root,COG0811@2|Bacteria,46VC6@74201|Verrucomicrobia,3K7Z8@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH3_k127_7685876_16	794903.OPIT5_22565	7.266e-33	132.0	COG0848@1|root,COG0848@2|Bacteria,46WER@74201|Verrucomicrobia,3K80N@414999|Opitutae	414999|Opitutae	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH3_k127_7685876_12	521674.Plim_2940	6.914e-74	254.0	COG1387@1|root,COG1387@2|Bacteria,2IZCF@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_7685876_1	595460.RRSWK_03801	9.609e-237	741.0	COG3119@1|root,COG3119@2|Bacteria,2IX2H@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_7685876_0	452637.Oter_0843	0.0	1252.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,46UHB@74201|Verrucomicrobia,3K7CZ@414999|Opitutae	2|Bacteria	C	PFAM FAD linked oxidase domain protein	MA20_43170	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
YHH3_k127_7685876_13	583355.Caka_1786	5.021e-71	244.0	COG1595@1|root,COG1595@2|Bacteria,46VNY@74201|Verrucomicrobia,3K8AY@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_7685876_2	583355.Caka_1785	1.498e-229	732.0	COG2304@1|root,COG5662@1|root,COG2304@2|Bacteria,COG5662@2|Bacteria,46SHE@74201|Verrucomicrobia,3KA2X@414999|Opitutae	414999|Opitutae	NU	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
YHH3_k127_7685876_3	243090.RB4880	2.468e-224	705.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_7685876_7	1408473.JHXO01000006_gene1130	1.457e-108	363.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,2FKZQ@200643|Bacteroidia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
YHH3_k127_7685876_8	1185876.BN8_04901	1.487e-100	337.0	COG3386@1|root,COG3386@2|Bacteria,4NIMX@976|Bacteroidetes,47KMQ@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
YHH3_k127_7685876_5	1121904.ARBP01000004_gene1028	3.788e-194	617.0	COG3119@1|root,COG3119@2|Bacteria,4NGJU@976|Bacteroidetes,47MMU@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_7685876_14	876044.IMCC3088_786	7.511e-69	257.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1J4YK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
YHH3_k127_7685876_19	595460.RRSWK_00077	1.145e-15	78.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_7685876_18	583355.Caka_0507	2.415e-21	96.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_7685876_6	1042376.AFPK01000062_gene1348	2.316e-180	584.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_7685876_9	869213.JCM21142_31327	6.265e-95	325.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.178	ko:K20830	-	-	-	-	ko00000,ko01000	-	GH16	-	Glyco_hydro_16
YHH3_k127_7685876_4	1121859.KB890739_gene2848	2.665e-194	616.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,47P1H@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_7685876_17	595460.RRSWK_03732	1.509e-27	115.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	fucA1	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_7725510_0	1123242.JH636434_gene3779	1.412e-170	549.0	2CCP0@1|root,2Z7XN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH3_k127_7725510_1	573065.Astex_2206	6.274e-67	245.0	COG0823@1|root,COG0823@2|Bacteria,1PQSK@1224|Proteobacteria,2UG73@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7725510_4	671143.DAMO_0713	7.086e-07	54.0	COG3077@1|root,COG3077@2|Bacteria	2|Bacteria	L	bacterial-type proximal promoter sequence-specific DNA binding	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
YHH3_k127_7725510_2	56107.Cylst_5848	4.486e-19	91.0	COG2337@1|root,COG2337@2|Bacteria,1GIQZ@1117|Cyanobacteria,1HPA0@1161|Nostocales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH3_k127_7725510_5	1122970.AUHC01000004_gene2378	1.992e-05	49.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2U066@28211|Alphaproteobacteria,2KDAM@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
YHH3_k127_7725510_3	715226.ABI_02750	3.706e-07	56.0	COG3177@1|root,COG3177@2|Bacteria,1NB0K@1224|Proteobacteria,2TTTS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH3_k127_7730877_2	1254432.SCE1572_10340	6.422e-14	83.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42QZT@68525|delta/epsilon subdivisions,2WK41@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
YHH3_k127_7730877_0	278957.ABEA03000186_gene1526	6.896e-125	412.0	COG4591@1|root,COG4591@2|Bacteria,46UC8@74201|Verrucomicrobia,3K7GQ@414999|Opitutae	414999|Opitutae	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
YHH3_k127_7730877_1	382464.ABSI01000020_gene182	2.683e-30	123.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
YHH3_k127_773903_0	690850.Desaf_1407	2.803e-18	100.0	COG1404@1|root,COG1404@2|Bacteria,1QU1I@1224|Proteobacteria,43D8N@68525|delta/epsilon subdivisions,2X8F9@28221|Deltaproteobacteria,2MAAF@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Subtilase family	-	-	3.4.21.61	ko:K01341	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	P_proprotein,Peptidase_S8
YHH3_k127_773903_2	523791.Kkor_0039	2.155e-11	77.0	COG4935@1|root,COG4935@2|Bacteria,1QZ17@1224|Proteobacteria,1T3ZK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein
YHH3_k127_773903_1	1173028.ANKO01000014_gene1062	2.074e-14	87.0	COG1572@1|root,COG1572@2|Bacteria,1G2VV@1117|Cyanobacteria,1HAEV@1150|Oscillatoriales	1117|Cyanobacteria	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
YHH3_k127_775964_0	595460.RRSWK_06820	1.409e-154	496.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_775964_2	886293.Sinac_3768	1.071e-37	151.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
YHH3_k127_775964_1	452637.Oter_2196	1.183e-115	381.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_7777770_0	583355.Caka_1849	4.029e-96	317.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia,3K756@414999|Opitutae	414999|Opitutae	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH3_k127_7777770_1	583355.Caka_1913	2.064e-55	199.0	COG2199@1|root,COG3706@2|Bacteria,46ST0@74201|Verrucomicrobia,3K80V@414999|Opitutae	414999|Opitutae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH3_k127_7777770_2	452637.Oter_3892	4.478e-42	157.0	COG1490@1|root,COG1490@2|Bacteria,46STH@74201|Verrucomicrobia,3K87C@414999|Opitutae	414999|Opitutae	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
YHH3_k127_7778688_0	1122605.KB893649_gene3750	3.009e-104	355.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1IS5G@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Laminin_G_3,Sulfatase
YHH3_k127_7778688_2	143224.JQMD01000002_gene1842	7.071e-13	81.0	2DBDK@1|root,2Z8MH@2|Bacteria,4NG4Q@976|Bacteroidetes,1I0VQ@117743|Flavobacteriia	976|Bacteroidetes	S	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
YHH3_k127_7778688_1	869213.JCM21142_42003	5.837e-34	135.0	COG1409@1|root,COG1409@2|Bacteria,4NF8E@976|Bacteroidetes,47MFG@768503|Cytophagia	976|Bacteroidetes	S	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
YHH3_k127_7836753_5	879212.DespoDRAFT_01808	3.255e-14	86.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42NWH@68525|delta/epsilon subdivisions,2WP4R@28221|Deltaproteobacteria,2MKAG@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
YHH3_k127_7836753_2	518766.Rmar_2392	1.637e-100	351.0	COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7836753_0	344747.PM8797T_24941	3.158e-206	652.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_7836753_3	314230.DSM3645_14025	5.318e-69	245.0	COG3828@1|root,COG3828@2|Bacteria,2J0AZ@203682|Planctomycetes	203682|Planctomycetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
YHH3_k127_7836753_4	502025.Hoch_2959	4.888e-19	91.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH3_k127_7836753_1	927658.AJUM01000047_gene3032	1.069e-128	416.0	COG4948@1|root,COG4948@2|Bacteria,4PKP3@976|Bacteroidetes,2FMI4@200643|Bacteroidia,3XIXJ@558415|Marinilabiliaceae	976|Bacteroidetes	M	Glycosyl-hydrolase 97 N-terminal	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97,Lipase_GDSL_2
YHH3_k127_7852556_2	583355.Caka_0705	9.867e-82	274.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_7852556_1	278957.ABEA03000106_gene1809	1.051e-234	736.0	COG0554@1|root,COG0554@2|Bacteria,46SJW@74201|Verrucomicrobia,3K7I5@414999|Opitutae	414999|Opitutae	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
YHH3_k127_7852556_0	382464.ABSI01000005_gene986	4.737e-248	775.0	COG0578@1|root,COG0578@2|Bacteria,46SDT@74201|Verrucomicrobia,2IU33@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,DAO_C
YHH3_k127_7852556_3	756272.Plabr_0104	9.901e-52	188.0	COG0657@1|root,COG0657@2|Bacteria,2IXCK@203682|Planctomycetes	203682|Planctomycetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,EF-hand_5,Peptidase_S9
YHH3_k127_7863053_0	313628.LNTAR_09771	2.268e-122	411.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_7863053_2	794903.OPIT5_06700	5.259e-23	103.0	COG1848@1|root,COG1848@2|Bacteria,46WDF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH3_k127_7863053_1	1121335.Clst_0783	1.278e-68	237.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
YHH3_k127_7866760_0	573063.Metin_0427	2.369e-42	164.0	COG0439@1|root,arCOG01590@2157|Archaea,2Y8CM@28890|Euryarchaeota,23QDY@183939|Methanococci	183939|Methanococci	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	pycA	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YHH3_k127_7866760_1	1304888.ATWF01000001_gene1216	1.396e-15	85.0	COG4770@1|root,COG4770@2|Bacteria,2GFGE@200930|Deferribacteres	200930|Deferribacteres	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
YHH3_k127_7866760_2	1121875.KB907556_gene616	9.979e-15	83.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes,1HYM1@117743|Flavobacteriia	976|Bacteroidetes	S	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
YHH3_k127_7874266_2	382464.ABSI01000011_gene2729	4.704e-142	458.0	COG0014@1|root,COG0014@2|Bacteria,46SGA@74201|Verrucomicrobia,2ITYN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH3_k127_7874266_4	583355.Caka_2116	2.793e-101	338.0	COG0157@1|root,COG0157@2|Bacteria,46UE1@74201|Verrucomicrobia,3K7T8@414999|Opitutae	414999|Opitutae	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
YHH3_k127_7874266_7	382464.ABSI01000011_gene2626	2.886e-71	252.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,46SX6@74201|Verrucomicrobia,2IUHW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
YHH3_k127_7874266_10	373903.Hore_11040	6.724e-46	175.0	COG1180@1|root,COG1180@2|Bacteria,1V1GP@1239|Firmicutes,24G76@186801|Clostridia,3WAJJ@53433|Halanaerobiales	186801|Clostridia	O	TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
YHH3_k127_7874266_1	583355.Caka_1434	3.205e-159	509.0	COG2805@1|root,COG2805@2|Bacteria,46SJF@74201|Verrucomicrobia,3K7CT@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH3_k127_7874266_5	1396141.BATP01000007_gene5537	9.247e-85	290.0	COG0329@1|root,COG0329@2|Bacteria,46SDY@74201|Verrucomicrobia,2ITUK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EM	Dihydrodipicolinate synthetase family	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YHH3_k127_7874266_6	583355.Caka_1436	1.867e-82	281.0	COG0289@1|root,COG0289@2|Bacteria,46SPR@74201|Verrucomicrobia,3K7A2@414999|Opitutae	414999|Opitutae	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
YHH3_k127_7874266_8	583355.Caka_1437	3.816e-57	207.0	COG0632@1|root,COG0632@2|Bacteria,46VFW@74201|Verrucomicrobia,3K80K@414999|Opitutae	414999|Opitutae	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
YHH3_k127_7874266_9	583355.Caka_1439	1.091e-46	175.0	COG1595@1|root,COG1595@2|Bacteria,46U3X@74201|Verrucomicrobia,3K7M2@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_7874266_17	1123229.AUBC01000025_gene4450	2.354e-05	48.0	COG5573@1|root,COG5573@2|Bacteria,1N454@1224|Proteobacteria,2UDGY@28211|Alphaproteobacteria,3K4AV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_7874266_14	41431.PCC8801_2973	9.116e-21	96.0	COG2361@1|root,COG2361@2|Bacteria,1G80M@1117|Cyanobacteria,3KISX@43988|Cyanothece	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
YHH3_k127_7874266_15	65393.PCC7424_0998	6.511e-17	84.0	COG1669@1|root,COG1669@2|Bacteria,1G804@1117|Cyanobacteria,3KK82@43988|Cyanothece	1117|Cyanobacteria	L	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
YHH3_k127_7874266_3	926550.CLDAP_17040	1.061e-106	390.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
YHH3_k127_7874266_13	1328313.DS2_09847	6.083e-24	120.0	COG2372@1|root,COG5276@1|root,COG2372@2|Bacteria,COG5276@2|Bacteria,1R46A@1224|Proteobacteria,1RY7V@1236|Gammaproteobacteria,46D9Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD
YHH3_k127_7874266_16	690850.Desaf_0283	3.205e-15	91.0	COG3266@1|root,COG3391@1|root,COG4870@1|root,COG3266@2|Bacteria,COG3391@2|Bacteria,COG4870@2|Bacteria,1NC9B@1224|Proteobacteria,42Z35@68525|delta/epsilon subdivisions,2WTVH@28221|Deltaproteobacteria,2MD34@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM Peptidase C1A, papain C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
YHH3_k127_7874266_0	713586.KB900536_gene1617	2.828e-177	573.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1WWF4@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH3_k127_7874266_11	688245.CtCNB1_3407	3.117e-29	118.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,2VW2Y@28216|Betaproteobacteria,4AEWN@80864|Comamonadaceae	28216|Betaproteobacteria	S	DNA-binding protein VF530	-	-	-	-	-	-	-	-	-	-	-	-	VF530
YHH3_k127_7874266_12	65093.PCC7418_3647	7.702e-25	108.0	COG3744@1|root,COG3744@2|Bacteria,1G647@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_7874266_18	1042209.HK44_016685	8.879e-05	48.0	COG4118@1|root,COG4118@2|Bacteria,1QSAF@1224|Proteobacteria,1RVPI@1236|Gammaproteobacteria,1YU7W@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH3_k127_7878438_0	1396141.BATP01000057_gene2930	1.046e-98	355.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
YHH3_k127_7878438_1	1121889.AUDM01000002_gene454	1.122e-26	113.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1HXC7@117743|Flavobacteriia,2NT1Y@237|Flavobacterium	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_7888925_10	313628.LNTAR_09776	1.36e-46	173.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_7888925_3	1268240.ATFI01000004_gene4410	1.783e-162	523.0	COG3507@1|root,COG3507@2|Bacteria,4NHJX@976|Bacteroidetes,2G2QR@200643|Bacteroidia,4APDF@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7888925_8	880073.Calab_0644	2.102e-72	258.0	COG0738@1|root,COG0738@2|Bacteria,2NQUK@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH3_k127_7888925_5	313628.LNTAR_09676	1.002e-130	431.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7888925_9	382464.ABSI01000017_gene43	8.988e-67	258.0	COG1629@1|root,COG1629@2|Bacteria,46UNV@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_7888925_11	742740.HMPREF9474_03596	2.053e-28	134.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
YHH3_k127_7888925_0	1336803.PHEL49_1330	3.231e-318	990.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,3VW0S@52959|Polaribacter	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
YHH3_k127_7888925_6	880073.Calab_0643	8.781e-117	390.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH3_k127_7888925_2	243090.RB607	4.433e-177	594.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_7888925_7	485918.Cpin_1583	1.443e-96	353.0	COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,1IX6E@117747|Sphingobacteriia	976|Bacteroidetes	G	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
YHH3_k127_7888925_4	313628.LNTAR_09801	2.758e-145	473.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.12	ko:K01135,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_7888925_1	1121904.ARBP01000001_gene5448	2.786e-189	601.0	COG2755@1|root,COG3669@1|root,COG2755@2|Bacteria,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_7888925_12	583355.Caka_0425	1.846e-19	91.0	COG3119@1|root,COG3119@2|Bacteria,46TNU@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_7891032_7	321327.CYA_0280	7.698e-10	75.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	exbB2	-	-	ko:K03561,ko:K12287	-	-	-	-	ko00000,ko02000,ko02044	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,MotA_ExbB
YHH3_k127_7891032_3	1237149.C900_04202	7.743e-20	108.0	COG2353@1|root,COG4099@1|root,COG4733@1|root,COG5498@1|root,COG2353@2|Bacteria,COG4099@2|Bacteria,COG4733@2|Bacteria,COG5498@2|Bacteria	2|Bacteria	M	chitin catabolic process	-	-	3.2.1.136	ko:K02358,ko:K15924	-	-	-	-	ko00000,ko01000,ko03012,ko03029,ko04147	-	GH5	-	Abhydrolase_8,CBM_6,PA14,RicinB_lectin_2,fn3
YHH3_k127_7891032_4	1150599.MPHLEI_02793	7.318e-17	98.0	COG3209@1|root,COG3209@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,RCC1_2
YHH3_k127_7891032_10	103733.JNYO01000096_gene4992	4.952e-06	63.0	COG2372@1|root,COG3266@1|root,COG2372@2|Bacteria,COG3266@2|Bacteria,2I302@201174|Actinobacteria,4EF87@85010|Pseudonocardiales	201174|Actinobacteria	S	response to copper ion	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082
YHH3_k127_7891032_5	1297742.A176_05903	1.262e-11	81.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K14475,ko:K20276	ko02024,ko05143,map02024,map05143	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,RCC1_2
YHH3_k127_7891032_9	926560.KE387023_gene1489	7.91e-07	64.0	COG3291@1|root,COG4676@1|root,COG3291@2|Bacteria,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,PKD,TPR_11,TPR_12,TPR_2,TPR_7,TPR_8
YHH3_k127_7891032_1	1121920.AUAU01000013_gene1721	2.056e-95	323.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_7891032_2	382464.ABSI01000010_gene3280	3.844e-44	169.0	2DB9P@1|root,2Z7Y1@2|Bacteria,46Z72@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_7891032_0	765913.ThidrDRAFT_3945	1.115e-110	366.0	COG4313@1|root,COG4313@2|Bacteria,1ND6Y@1224|Proteobacteria,1RYD3@1236|Gammaproteobacteria,1WW33@135613|Chromatiales	135613|Chromatiales	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YHH3_k127_7891032_6	1279019.ARQK01000027_gene2455	7.273e-11	68.0	COG4113@1|root,COG4113@2|Bacteria,1NB4U@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_7891032_11	118168.MC7420_7316	9.113e-06	59.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7HR@1150|Oscillatoriales	1117|Cyanobacteria	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,SpoIIE,TIR_2,WD40
YHH3_k127_7897632_1	929713.NIASO_04940	9.521e-64	222.0	COG3119@1|root,COG3119@2|Bacteria,4NEFN@976|Bacteroidetes,1IQ0C@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
YHH3_k127_7897632_0	1122931.AUAE01000006_gene3124	9.058e-72	257.0	COG0639@1|root,COG0639@2|Bacteria,4NZWK@976|Bacteroidetes,2FPXD@200643|Bacteroidia	976|Bacteroidetes	T	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
YHH3_k127_7916956_2	290318.Cvib_0740	1.72e-32	131.0	COG1342@1|root,COG1342@2|Bacteria,1FF1T@1090|Chlorobi	1090|Chlorobi	S	Belongs to the UPF0251 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
YHH3_k127_7916956_1	452637.Oter_2645	2.61e-51	191.0	COG2866@1|root,COG2866@2|Bacteria,46T00@74201|Verrucomicrobia,3K83I@414999|Opitutae	414999|Opitutae	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
YHH3_k127_7916956_0	426368.MmarC7_1556	3.474e-61	218.0	arCOG06621@1|root,arCOG06621@2157|Archaea,2Y3GZ@28890|Euryarchaeota,23RKE@183939|Methanococci	183939|Methanococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7920911_1	583355.Caka_1869	1.672e-164	529.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,46U9T@74201|Verrucomicrobia,3K7GP@414999|Opitutae	414999|Opitutae	E	glutamate synthase	-	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
YHH3_k127_7920911_7	649349.Lbys_2037	1.141e-31	133.0	COG2935@1|root,COG2935@2|Bacteria,4P1RD@976|Bacteroidetes,47U44@768503|Cytophagia	976|Bacteroidetes	O	PFAM Arginine-tRNA-protein transferase, C terminus	-	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	Acetyltransf_6
YHH3_k127_7920911_3	760568.Desku_1150	4.281e-91	317.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,260X6@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH3_k127_7920911_0	583355.Caka_1312	1.85e-234	740.0	COG2804@1|root,COG2804@2|Bacteria,46TEW@74201|Verrucomicrobia,3K94U@414999|Opitutae	414999|Opitutae	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
YHH3_k127_7920911_4	583355.Caka_1313	8.211e-44	176.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH3_k127_7920911_5	583355.Caka_1314	1.155e-42	171.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH3_k127_7920911_2	123214.PERMA_0490	5.28e-99	334.0	COG0536@1|root,COG0536@2|Bacteria,2G3N0@200783|Aquificae	200783|Aquificae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
YHH3_k127_7920911_6	583355.Caka_1453	1.258e-38	147.0	COG2197@1|root,COG2197@2|Bacteria,46T2B@74201|Verrucomicrobia,3K7X9@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_7946594_0	583355.Caka_2506	2.187e-300	934.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,3K7KM@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YHH3_k127_7946594_2	794903.OPIT5_27990	9.504e-119	390.0	COG0788@1|root,COG0788@2|Bacteria,46SMH@74201|Verrucomicrobia,3K78Z@414999|Opitutae	414999|Opitutae	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
YHH3_k127_7946594_4	523791.Kkor_1648	4.442e-34	134.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,1S11K@1236|Gammaproteobacteria,1XPP9@135619|Oceanospirillales	135619|Oceanospirillales	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
YHH3_k127_7946594_1	583355.Caka_2558	1.713e-235	737.0	COG0442@1|root,COG0442@2|Bacteria,46SE3@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
YHH3_k127_7946594_3	794903.OPIT5_07035	2.044e-73	252.0	COG0323@1|root,COG3170@1|root,COG0323@2|Bacteria,COG3170@2|Bacteria,46SG5@74201|Verrucomicrobia,3K76S@414999|Opitutae	414999|Opitutae	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
YHH3_k127_7952585_3	7091.BGIBMGA009555-TA	1.13e-11	68.0	COG0666@1|root,KOG4177@2759|Eukaryota,38EUY@33154|Opisthokonta,3BAA9@33208|Metazoa,3CRYK@33213|Bilateria,41TKM@6656|Arthropoda,3SI1R@50557|Insecta,445SQ@7088|Lepidoptera	33208|Metazoa	M	Ankyrin repeat	TNKS2	GO:0000209,GO:0000226,GO:0000228,GO:0000242,GO:0000278,GO:0000723,GO:0000781,GO:0000784,GO:0000922,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0005654,GO:0005694,GO:0005737,GO:0005794,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006471,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007063,GO:0007088,GO:0007346,GO:0008104,GO:0008150,GO:0008152,GO:0008270,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0010948,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016310,GO:0016567,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0022402,GO:0022607,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033046,GO:0033047,GO:0033048,GO:0033365,GO:0034091,GO:0034092,GO:0034182,GO:0034183,GO:0034502,GO:0034613,GO:0034641,GO:0035264,GO:0036211,GO:0040007,GO:0040008,GO:0040014,GO:0042176,GO:0042393,GO:0042592,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043392,GO:0043412,GO:0044085,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044451,GO:0044454,GO:0044464,GO:0045732,GO:0045786,GO:0045839,GO:0045862,GO:0045875,GO:0045893,GO:0045930,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046872,GO:0046914,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048638,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051098,GO:0051100,GO:0051101,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051225,GO:0051239,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051276,GO:0051338,GO:0051347,GO:0051641,GO:0051726,GO:0051783,GO:0051784,GO:0051972,GO:0051973,GO:0051983,GO:0051985,GO:0060249,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0070925,GO:0071704,GO:0071840,GO:0072686,GO:0080090,GO:0090263,GO:0090304,GO:0090364,GO:0097110,GO:0097431,GO:0098687,GO:1901360,GO:1901564,GO:1902680,GO:1902850,GO:1903047,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1903506,GO:1903508,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:1904742,GO:1904743,GO:1904907,GO:1904908,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001141,GO:2001251,GO:2001252	2.4.2.30	ko:K10799	-	-	-	-	ko00000,ko01000,ko03032,ko03036	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,PARP,SAM_2
YHH3_k127_7952585_0	439497.RR11_979	1.461e-136	443.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2TTY9@28211|Alphaproteobacteria,4NCUC@97050|Ruegeria	28211|Alphaproteobacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
YHH3_k127_7952585_2	65093.PCC7418_1179	2.345e-12	70.0	COG3620@1|root,COG3620@2|Bacteria,1G9PF@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
YHH3_k127_7952585_1	1397278.AYMV01000030_gene2424	6.734e-27	115.0	28NCN@1|root,2ZBFM@2|Bacteria,2HCM3@201174|Actinobacteria	201174|Actinobacteria	L	restriction endonuclease	naeIR	-	-	-	-	-	-	-	-	-	-	-	NaeI
YHH3_k127_7970603_5	1434325.AZQN01000005_gene3676	1.611e-09	61.0	COG3119@1|root,COG3119@2|Bacteria,4NE9D@976|Bacteroidetes,47T9R@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_7970603_2	349521.HCH_00109	7.612e-83	280.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,1XIDW@135619|Oceanospirillales	135619|Oceanospirillales	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
YHH3_k127_7970603_4	1304275.C41B8_05113	4.051e-35	139.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,1S6HB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YHH3_k127_7970603_3	278957.ABEA03000152_gene4082	4.795e-51	182.0	COG0695@1|root,COG0695@2|Bacteria,46SXS@74201|Verrucomicrobia,3K871@414999|Opitutae	414999|Opitutae	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
YHH3_k127_7970603_1	278957.ABEA03000212_gene3799	3.276e-91	309.0	COG0682@1|root,COG0682@2|Bacteria,46SSY@74201|Verrucomicrobia,3K7Y7@414999|Opitutae	414999|Opitutae	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
YHH3_k127_7970603_0	583355.Caka_1537	2.257e-99	336.0	COG1253@1|root,COG1253@2|Bacteria,46UX9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
YHH3_k127_7986987_1	644282.Deba_3173	4.111e-58	203.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
YHH3_k127_7986987_0	335543.Sfum_3402	2.243e-81	276.0	COG0425@1|root,COG0425@2|Bacteria,1N08X@1224|Proteobacteria,42RUG@68525|delta/epsilon subdivisions,2WNNK@28221|Deltaproteobacteria,2MQI2@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	yedF	-	-	-	-	-	-	-	-	-	-	-	DrsE,TusA
YHH3_k127_799117_4	583355.Caka_0439	1.56e-69	249.0	COG1757@1|root,COG1757@2|Bacteria	2|Bacteria	C	Na H antiporter	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
YHH3_k127_799117_0	583355.Caka_0913	1.682e-149	482.0	COG0820@1|root,COG0820@2|Bacteria,46UPK@74201|Verrucomicrobia,3K7AA@414999|Opitutae	414999|Opitutae	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
YHH3_k127_799117_3	583355.Caka_1393	9.366e-91	308.0	COG0685@1|root,COG0685@2|Bacteria,46U74@74201|Verrucomicrobia,3K7A3@414999|Opitutae	414999|Opitutae	C	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
YHH3_k127_799117_2	794903.OPIT5_06525	4.721e-98	330.0	COG4974@1|root,COG4974@2|Bacteria,46SSD@74201|Verrucomicrobia,3K7RA@414999|Opitutae	414999|Opitutae	D	tyrosine recombinase	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH3_k127_799117_1	452637.Oter_2793	2.028e-126	422.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,46SH2@74201|Verrucomicrobia,3K7MN@414999|Opitutae	414999|Opitutae	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
YHH3_k127_799117_6	272624.lpg1742	1.497e-05	53.0	2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria,1JFBK@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_799117_5	382464.ABSI01000013_gene1770	2.739e-28	122.0	COG1579@1|root,COG1579@2|Bacteria,46T10@74201|Verrucomicrobia,2IUE8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
YHH3_k127_8011794_2	856793.MICA_2206	4.282e-72	252.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2TUX0@28211|Alphaproteobacteria,4BQK2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
YHH3_k127_8011794_0	1209072.ALBT01000077_gene432	6.81e-151	488.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,1FI4A@10|Cellvibrio	1236|Gammaproteobacteria	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
YHH3_k127_8011794_1	1209072.ALBT01000077_gene433	4.407e-101	345.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,1RQPH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YHH3_k127_8011794_3	187303.BN69_3104	1.437e-12	67.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria,36XS9@31993|Methylocystaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	ragA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH3_k127_8027943_2	1121918.ARWE01000001_gene2468	1.65e-67	243.0	COG0531@1|root,COG0531@2|Bacteria,1R4IZ@1224|Proteobacteria,42MTQ@68525|delta/epsilon subdivisions,2WK39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,SLC12
YHH3_k127_8027943_0	1168034.FH5T_19355	3.152e-140	460.0	COG1387@1|root,COG1387@2|Bacteria,4NMBC@976|Bacteroidetes,2FNU7@200643|Bacteroidia	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_8027943_1	313606.M23134_07068	1.354e-105	362.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KVI@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
YHH3_k127_8043090_1	1121904.ARBP01000027_gene738	4.668e-88	300.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_8043090_2	930171.Asphe3_10590	1.119e-60	224.0	COG1874@1|root,COG1874@2|Bacteria,2IAE5@201174|Actinobacteria,1WB3G@1268|Micrococcaceae	201174|Actinobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8043090_0	756272.Plabr_2092	4.114e-164	528.0	COG3119@1|root,COG3119@2|Bacteria,2J24M@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_8043090_5	1502852.FG94_02232	4.425e-06	59.0	2DK92@1|root,308WT@2|Bacteria,1R9RX@1224|Proteobacteria,2W5PF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8043090_3	926566.Terro_3759	4.891e-27	118.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria,2JI4A@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_8047448_3	598659.NAMH_1184	7.581e-09	59.0	2AY0S@1|root,31Q2B@2|Bacteria,1QMQY@1224|Proteobacteria,42SY0@68525|delta/epsilon subdivisions,2YPGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
YHH3_k127_8047448_2	452637.Oter_3639	1.545e-09	69.0	28Q9D@1|root,2ZCS4@2|Bacteria,46WV1@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8047448_1	583355.Caka_0060	5.06e-18	86.0	2E9BS@1|root,333JI@2|Bacteria	2|Bacteria	S	metal-binding protein	yecH	-	-	-	-	-	-	-	-	-	-	-	DUF2492
YHH3_k127_8047448_0	1121939.L861_22675	1.092e-84	293.0	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,1RMJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YHH3_k127_8050795_2	452637.Oter_2533	1.377e-105	354.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia,3K7P8@414999|Opitutae	414999|Opitutae	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
YHH3_k127_8050795_0	1396418.BATQ01000056_gene185	2.423e-214	697.0	COG0612@1|root,COG0612@2|Bacteria,46UTT@74201|Verrucomicrobia,2ITM2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH3_k127_8050795_3	452637.Oter_2556	2.189e-101	336.0	COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia,3K7US@414999|Opitutae	414999|Opitutae	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
YHH3_k127_8050795_5	583355.Caka_2448	4.902e-17	80.0	COG0257@1|root,COG0257@2|Bacteria,46TAZ@74201|Verrucomicrobia,3K8GV@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
YHH3_k127_8050795_4	794903.OPIT5_19580	1.024e-28	117.0	COG0254@1|root,COG0254@2|Bacteria,46XUU@74201|Verrucomicrobia,3K8B9@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL31 family	-	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
YHH3_k127_8050795_7	105420.BBPO01000007_gene2555	3.682e-09	67.0	COG3595@1|root,COG3595@2|Bacteria,2GKT3@201174|Actinobacteria,2NGPP@228398|Streptacidiphilus	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
YHH3_k127_8050795_1	1122134.KB893650_gene1319	4.112e-209	663.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XJ36@135619|Oceanospirillales	135619|Oceanospirillales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YHH3_k127_8050795_6	62928.azo2810	1.578e-11	70.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,2KWVI@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH3_k127_8070993_1	313628.LNTAR_16613	2.268e-31	128.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
YHH3_k127_8124092_1	1968.JOEV01000013_gene855	2.063e-12	80.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria	201174|Actinobacteria	M	PFAM peptidase M6, immune inhibitor A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
YHH3_k127_8124092_0	1192034.CAP_8119	4.737e-80	290.0	COG5184@1|root,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2YV9Z@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
YHH3_k127_8135720_3	583355.Caka_1474	4.216e-55	201.0	COG2836@1|root,COG2836@2|Bacteria,46VBD@74201|Verrucomicrobia,3K9GV@414999|Opitutae	414999|Opitutae	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
YHH3_k127_8135720_1	452637.Oter_4082	3.809e-192	626.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,46UK0@74201|Verrucomicrobia,3K77D@414999|Opitutae	414999|Opitutae	P	E1-E2 ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,Hydrolase
YHH3_k127_8135720_4	583355.Caka_2351	2.913e-36	156.0	COG3307@1|root,COG3307@2|Bacteria,46XGV@74201|Verrucomicrobia,3K792@414999|Opitutae	414999|Opitutae	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH3_k127_8135720_0	583355.Caka_0684	1.167e-224	714.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia,3K7QQ@414999|Opitutae	414999|Opitutae	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YHH3_k127_8135720_2	583355.Caka_2931	9.011e-174	559.0	COG0738@1|root,COG0738@2|Bacteria,46TFW@74201|Verrucomicrobia,3K9UU@414999|Opitutae	414999|Opitutae	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH3_k127_8162486_0	583355.Caka_2607	4.24e-178	568.0	COG0498@1|root,COG0498@2|Bacteria,46TPG@74201|Verrucomicrobia,3K7E5@414999|Opitutae	414999|Opitutae	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
YHH3_k127_8162486_1	382464.ABSI01000005_gene1018	6.955e-54	193.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia,2ITJM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
YHH3_k127_817293_0	283942.IL2166	1.069e-137	447.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,2QFFB@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
YHH3_k127_8173133_0	382464.ABSI01000007_gene4078	9.911e-65	241.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE5,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
YHH3_k127_8188291_1	313628.LNTAR_12041	9.456e-68	239.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Lipase_GDSL_2,Peptidase_S9
YHH3_k127_8188291_0	344747.PM8797T_10239	2.944e-73	251.0	COG3119@1|root,COG3119@2|Bacteria,2J1XV@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_8210224_5	583355.Caka_1683	6.801e-54	191.0	COG0092@1|root,COG0092@2|Bacteria,46SN9@74201|Verrucomicrobia,3K776@414999|Opitutae	414999|Opitutae	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YHH3_k127_8210224_4	583355.Caka_1682	5.051e-54	192.0	COG0197@1|root,COG0197@2|Bacteria,46ST6@74201|Verrucomicrobia,3K7Z4@414999|Opitutae	414999|Opitutae	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
YHH3_k127_8210224_13	278957.ABEA03000071_gene3048	6.944e-11	66.0	COG0255@1|root,COG0255@2|Bacteria,46WKJ@74201|Verrucomicrobia,3K8FF@414999|Opitutae	414999|Opitutae	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
YHH3_k127_8210224_11	583355.Caka_1680	2.156e-33	132.0	COG0186@1|root,COG0186@2|Bacteria,46T6M@74201|Verrucomicrobia,3K88E@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
YHH3_k127_8210224_6	382464.ABSI01000011_gene2660	7.785e-51	183.0	COG0093@1|root,COG0093@2|Bacteria,46VID@74201|Verrucomicrobia,2IUB7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
YHH3_k127_8210224_12	382464.ABSI01000011_gene2659	2.549e-19	94.0	COG0198@1|root,COG0198@2|Bacteria,46T3M@74201|Verrucomicrobia,2IUUE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal proteins 50S L24/mitochondrial 39S L24	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
YHH3_k127_8210224_2	583355.Caka_1677	6.317e-65	227.0	COG0094@1|root,COG0094@2|Bacteria,46SP7@74201|Verrucomicrobia,3K7AF@414999|Opitutae	414999|Opitutae	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
YHH3_k127_8210224_8	583355.Caka_1676	1.052e-43	162.0	COG0199@1|root,COG0199@2|Bacteria,46X64@74201|Verrucomicrobia,3K84A@414999|Opitutae	414999|Opitutae	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
YHH3_k127_8210224_9	382464.ABSI01000011_gene2656	8.032e-36	141.0	COG0096@1|root,COG0096@2|Bacteria,46T2K@74201|Verrucomicrobia,2IUCT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
YHH3_k127_8210224_3	794903.OPIT5_02350	6.59e-64	224.0	COG0097@1|root,COG0097@2|Bacteria,46SP9@74201|Verrucomicrobia,3K7WU@414999|Opitutae	414999|Opitutae	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
YHH3_k127_8210224_10	583355.Caka_1673	4.61e-35	138.0	COG0256@1|root,COG0256@2|Bacteria,46YZJ@74201|Verrucomicrobia,3K85Y@414999|Opitutae	414999|Opitutae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
YHH3_k127_8210224_1	382464.ABSI01000011_gene2653	4.582e-65	229.0	COG0098@1|root,COG0098@2|Bacteria,46SUR@74201|Verrucomicrobia,2IUC7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
YHH3_k127_8210224_7	583355.Caka_1671	4.625e-44	165.0	COG0200@1|root,COG0200@2|Bacteria,46VGD@74201|Verrucomicrobia,3K832@414999|Opitutae	414999|Opitutae	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
YHH3_k127_8210224_0	382464.ABSI01000011_gene2651	8.601e-156	499.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,2ITRX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YHH3_k127_8214118_8	452637.Oter_2641	6.966e-64	226.0	COG0206@1|root,COG0206@2|Bacteria,46UAJ@74201|Verrucomicrobia,3K7KG@414999|Opitutae	414999|Opitutae	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YHH3_k127_8214118_4	583355.Caka_3076	1.916e-98	335.0	COG0849@1|root,COG0849@2|Bacteria,46SQI@74201|Verrucomicrobia,3K782@414999|Opitutae	414999|Opitutae	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
YHH3_k127_8214118_11	452637.Oter_2639	9.838e-23	107.0	COG1589@1|root,COG1589@2|Bacteria,46T4T@74201|Verrucomicrobia,3K847@414999|Opitutae	414999|Opitutae	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	POTRA_1
YHH3_k127_8214118_10	583355.Caka_3074	3.428e-61	222.0	COG1181@1|root,COG1181@2|Bacteria,46UAF@74201|Verrucomicrobia,3K7WF@414999|Opitutae	414999|Opitutae	M	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
YHH3_k127_8214118_7	452637.Oter_2636	5.078e-90	309.0	COG0707@1|root,COG0707@2|Bacteria,46UBI@74201|Verrucomicrobia,3KA2U@414999|Opitutae	414999|Opitutae	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
YHH3_k127_8214118_3	583355.Caka_3071	6.906e-117	387.0	COG0772@1|root,COG0772@2|Bacteria,46SMC@74201|Verrucomicrobia,3K7ID@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
YHH3_k127_8214118_12	665952.HMPREF1015_02058	1.295e-21	108.0	COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus	91061|Bacilli	M	COG1388 FOG LysM repeat	cwlS	-	-	ko:K19223,ko:K19224	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60,SH3_3
YHH3_k127_8214118_9	382464.ABSI01000002_gene4358	4.678e-63	234.0	COG0771@1|root,COG0771@2|Bacteria,46UUH@74201|Verrucomicrobia,2ITN5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH3_k127_8214118_1	583355.Caka_3068	1.198e-151	488.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia,3K7EK@414999|Opitutae	414999|Opitutae	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
YHH3_k127_8214118_6	452637.Oter_2630	8.806e-96	331.0	COG0770@1|root,COG0770@2|Bacteria,46UDV@74201|Verrucomicrobia,3K7ND@414999|Opitutae	414999|Opitutae	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	-	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH3_k127_8214118_2	583355.Caka_3066	6.862e-133	441.0	COG0769@1|root,COG0769@2|Bacteria,46SGG@74201|Verrucomicrobia,3K7EA@414999|Opitutae	414999|Opitutae	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH3_k127_8214118_0	583355.Caka_3065	6.006e-170	551.0	COG0768@1|root,COG0768@2|Bacteria,46SEZ@74201|Verrucomicrobia,3K799@414999|Opitutae	414999|Opitutae	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
YHH3_k127_8214118_5	583355.Caka_3062	3.449e-98	330.0	COG0275@1|root,COG0275@2|Bacteria,46UYN@74201|Verrucomicrobia,3K74T@414999|Opitutae	414999|Opitutae	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
YHH3_k127_8223915_0	583355.Caka_1131	3.277e-106	353.0	COG1702@1|root,COG1702@2|Bacteria,46S7S@74201|Verrucomicrobia,3K7UY@414999|Opitutae	414999|Opitutae	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
YHH3_k127_8223915_3	583355.Caka_1130	4.392e-53	191.0	COG0537@1|root,COG0537@2|Bacteria,46T23@74201|Verrucomicrobia,3K81F@414999|Opitutae	414999|Opitutae	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
YHH3_k127_8223915_2	1415630.U771_30580	3.541e-82	278.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,1RMDJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate	elbB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009893,GO:0009987,GO:0019216,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045828,GO:0045834,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:0080090,GO:1901576	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
YHH3_k127_8223915_4	583355.Caka_3134	4.459e-24	107.0	COG1934@1|root,COG1934@2|Bacteria,46WSW@74201|Verrucomicrobia,3K8DV@414999|Opitutae	414999|Opitutae	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm	-	-	-	-	-	-	-	-	-	-	-	-	LptC
YHH3_k127_8223915_6	382464.ABSI01000010_gene3767	3.534e-17	91.0	COG1934@1|root,COG1934@2|Bacteria	2|Bacteria	S	lipopolysaccharide binding	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_2
YHH3_k127_8223915_1	583355.Caka_3135	2.16e-99	336.0	COG1137@1|root,COG1137@2|Bacteria,46SDI@74201|Verrucomicrobia,3K77F@414999|Opitutae	414999|Opitutae	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
YHH3_k127_8223915_5	583355.Caka_3136	4.608e-18	87.0	COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia,3K7RB@414999|Opitutae	414999|Opitutae	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
YHH3_k127_8232870_4	221288.JH992901_gene692	7.992e-17	81.0	2B766@1|root,3207Z@2|Bacteria,1G9KP@1117|Cyanobacteria,1JMIJ@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8232870_2	449447.MAE_51010	1.288e-37	143.0	arCOG07672@1|root,32Z5Y@2|Bacteria,1G846@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
YHH3_k127_8232870_1	1162668.LFE_0136	1.379e-41	154.0	COG3636@1|root,COG3636@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8232870_0	449447.MAE_47250	3.199e-45	164.0	COG3657@1|root,COG3657@2|Bacteria,1G6YT@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
YHH3_k127_8232870_3	32049.SYNPCC7002_A2582	6.456e-24	102.0	COG3431@1|root,COG3431@2|Bacteria,1GDQ1@1117|Cyanobacteria	1117|Cyanobacteria	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
YHH3_k127_8237643_2	583355.Caka_0927	5.457e-164	523.0	COG2812@1|root,COG2812@2|Bacteria,46SGC@74201|Verrucomicrobia,3K7MI@414999|Opitutae	414999|Opitutae	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
YHH3_k127_8237643_9	1388763.O165_025720	3.836e-32	134.0	COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,1SBPT@1236|Gammaproteobacteria,1YX40@136845|Pseudomonas putida group	1236|Gammaproteobacteria	E	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT_4,ACT_6
YHH3_k127_8237643_5	43989.cce_3696	8.663e-137	446.0	COG1453@1|root,COG1453@2|Bacteria,1G1CE@1117|Cyanobacteria,3KH0C@43988|Cyanothece	1117|Cyanobacteria	S	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
YHH3_k127_8237643_1	583355.Caka_2974	5.042e-166	539.0	COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia,3K7KZ@414999|Opitutae	414999|Opitutae	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
YHH3_k127_8237643_8	1123070.KB899255_gene1403	7.068e-48	186.0	COG3528@1|root,COG3528@2|Bacteria,46WUE@74201|Verrucomicrobia,2IUWW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
YHH3_k127_8237643_3	382464.ABSI01000020_gene232	8.294e-152	501.0	COG4166@1|root,COG4166@2|Bacteria,46TR7@74201|Verrucomicrobia,2IWMV@203494|Verrucomicrobiae	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iECABU_c1320.ECABU_c15240,iECNA114_1301.ECNA114_1414,iECSF_1327.ECSF_1224,iNRG857_1313.NRG857_06385,iUMNK88_1353.UMNK88_1667	SBP_bac_5
YHH3_k127_8237643_7	583355.Caka_1469	3.931e-85	287.0	COG0321@1|root,COG0321@2|Bacteria,46T11@74201|Verrucomicrobia,3K7XY@414999|Opitutae	414999|Opitutae	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YHH3_k127_8237643_6	583355.Caka_1470	6.092e-132	426.0	COG0320@1|root,COG0320@2|Bacteria,46TZG@74201|Verrucomicrobia,3K7A4@414999|Opitutae	414999|Opitutae	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
YHH3_k127_8237643_0	765912.Thimo_0097	3.896e-173	553.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1WWT4@135613|Chromatiales	135613|Chromatiales	U	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
YHH3_k127_8237643_4	572477.Alvin_2162	2.194e-151	485.0	COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,1RPPW@1236|Gammaproteobacteria,1WW82@135613|Chromatiales	135613|Chromatiales	E	PFAM Pyruvate carboxyltransferase	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
YHH3_k127_8284911_3	1396141.BATP01000039_gene1333	7.236e-58	209.0	COG0637@1|root,COG0637@2|Bacteria,46SWS@74201|Verrucomicrobia,2IUCX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH3_k127_8284911_7	382464.ABSI01000023_gene517	3.092e-33	132.0	COG3791@1|root,COG3791@2|Bacteria,46XNA@74201|Verrucomicrobia,2IW8Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
YHH3_k127_8284911_4	382464.ABSI01000020_gene354	2.905e-56	201.0	COG5319@1|root,COG5319@2|Bacteria,46VM9@74201|Verrucomicrobia,2IVSB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8284911_5	1234364.AMSF01000086_gene2834	7.614e-55	196.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,1S5WS@1236|Gammaproteobacteria,1X5DN@135614|Xanthomonadales	135614|Xanthomonadales	EJ	asparaginase	VL23_12675	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
YHH3_k127_8284911_9	891968.Anamo_2010	1.52e-08	66.0	COG1459@1|root,COG1459@2|Bacteria,3T9XV@508458|Synergistetes	508458|Synergistetes	U	Type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH3_k127_8284911_11	378806.STAUR_5642	6.473e-05	57.0	COG2372@1|root,COG2372@2|Bacteria,1QSPC@1224|Proteobacteria,433ZQ@68525|delta/epsilon subdivisions,2X4A7@28221|Deltaproteobacteria,2YYKU@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
YHH3_k127_8284911_8	926560.KE387023_gene1539	4.281e-18	100.0	2DXZ1@1|root,34790@2|Bacteria,1WN4B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8284911_1	1122194.AUHU01000004_gene1588	1.589e-93	313.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,465DF@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
YHH3_k127_8284911_0	583355.Caka_1844	0.0	1195.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,46S4N@74201|Verrucomicrobia,3K7B9@414999|Opitutae	414999|Opitutae	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
YHH3_k127_8284911_2	382464.ABSI01000020_gene197	2.969e-69	242.0	COG1187@1|root,COG1187@2|Bacteria,46SWQ@74201|Verrucomicrobia,2IUBZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA pseudouridylate synthase	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH3_k127_8284911_10	382464.ABSI01000020_gene196	1.046e-06	59.0	COG3416@1|root,COG3416@2|Bacteria,46WKS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8284911_6	583355.Caka_1322	2.327e-50	183.0	COG0190@1|root,COG0190@2|Bacteria,46TG7@74201|Verrucomicrobia,3K7QM@414999|Opitutae	414999|Opitutae	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
YHH3_k127_8292017_0	313628.LNTAR_19497	2.757e-306	954.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
YHH3_k127_8304703_5	794903.OPIT5_28555	2.853e-11	67.0	COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia,3K7EE@414999|Opitutae	414999|Opitutae	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
YHH3_k127_8304703_1	452637.Oter_2070	8.055e-71	245.0	COG1845@1|root,COG1845@2|Bacteria,46T4X@74201|Verrucomicrobia,3K7X1@414999|Opitutae	414999|Opitutae	C	oxidase subunit III	-	-	-	ko:K02299	ko00190,ko01100,map00190,map01100	M00417	-	-	ko00000,ko00001,ko00002	3.D.4.5	-	-	COX3
YHH3_k127_8304703_4	794903.OPIT5_28565	8.577e-18	87.0	COG3125@1|root,COG3125@2|Bacteria,46XUX@74201|Verrucomicrobia,3K8BJ@414999|Opitutae	414999|Opitutae	C	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
YHH3_k127_8304703_0	583355.Caka_0652	2.355e-72	252.0	COG3336@1|root,COG3336@2|Bacteria,46XMC@74201|Verrucomicrobia,3K7KA@414999|Opitutae	414999|Opitutae	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
YHH3_k127_8304703_3	583355.Caka_1789	9.386e-56	207.0	COG0248@1|root,COG0248@2|Bacteria,46T7T@74201|Verrucomicrobia,3K7WZ@414999|Opitutae	414999|Opitutae	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
YHH3_k127_8304703_2	452637.Oter_3016	3.861e-66	233.0	COG0313@1|root,COG0313@2|Bacteria,46SVC@74201|Verrucomicrobia,3K7C1@414999|Opitutae	414999|Opitutae	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YHH3_k127_8304703_6	278957.ABEA03000025_gene1674	0.0001562	45.0	2A5YQ@1|root,30UQT@2|Bacteria,46YP5@74201|Verrucomicrobia,3K9X7@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_831034_0	452637.Oter_1542	3.766e-33	137.0	COG0697@1|root,COG0697@2|Bacteria,46SR7@74201|Verrucomicrobia	2|Bacteria	EG	EamA-like transporter family	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
YHH3_k127_831034_2	1265313.HRUBRA_00981	4.172e-21	109.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,1J5AV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB dependent receptor	oprC	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH3_k127_831034_1	1313304.CALK_1524	2.566e-31	125.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH3_k127_8332259_0	1303518.CCALI_02567	4.018e-55	220.0	28KZU@1|root,2ZAF0@2|Bacteria	2|Bacteria	G	Rhamnogalacturonate lyase	-	GO:0005575,GO:0005576	4.2.2.23	ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,Rhamnogal_lyase,fn3_3
YHH3_k127_8340354_0	243233.MCA1906	1.22e-88	307.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RZFF@1236|Gammaproteobacteria,1XF0J@135618|Methylococcales	135618|Methylococcales	C	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
YHH3_k127_8341793_0	644966.Tmar_2153	6.135e-24	117.0	COG1373@1|root,COG1373@2|Bacteria,1TPFF@1239|Firmicutes,24CP6@186801|Clostridia,3WCW6@538999|Clostridiales incertae sedis	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_8341793_1	760568.Desku_3205	2.654e-19	89.0	COG1743@1|root,COG1743@2|Bacteria,1TRIT@1239|Firmicutes,24AVX@186801|Clostridia,262DB@186807|Peptococcaceae	186801|Clostridia	L	DNA methylase	-	-	-	ko:K07445	-	-	-	-	ko00000	-	-	-	DUF1156
YHH3_k127_8350233_0	459349.CLOAM1811	7.626e-52	201.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K06987,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,DUF4859,FlgD_ig,Peptidase_M14
YHH3_k127_8350233_1	926562.Oweho_3428	5.223e-10	67.0	COG3291@1|root,COG3291@2|Bacteria,4NI4A@976|Bacteroidetes,1I44J@117743|Flavobacteriia	976|Bacteroidetes	L	MAM domain, meprin/A5/mu	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,fn3
YHH3_k127_8361260_2	756272.Plabr_4230	3.684e-67	235.0	COG1802@1|root,COG1802@2|Bacteria,2J0K9@203682|Planctomycetes	203682|Planctomycetes	K	COG1802 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
YHH3_k127_8361260_0	344747.PM8797T_05970	1.221e-271	852.0	COG4692@1|root,COG4692@2|Bacteria,2IX4M@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
YHH3_k127_8361260_1	243090.RB352	5.834e-133	435.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_8370340_2	1408422.JHYF01000003_gene934	1.772e-15	83.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,36FVM@31979|Clostridiaceae	186801|Clostridia	S	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
YHH3_k127_8370340_1	886293.Sinac_4290	8.374e-101	342.0	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
YHH3_k127_8370340_0	583355.Caka_0491	3.952e-108	357.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
YHH3_k127_8373286_0	1123008.KB905693_gene1116	1.137e-208	661.0	2DBRS@1|root,2ZAN1@2|Bacteria,4PNNC@976|Bacteroidetes,2G18D@200643|Bacteroidia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
YHH3_k127_8373286_1	1347342.BN863_21290	1.856e-145	473.0	COG3119@1|root,COG3119@2|Bacteria,4NGJU@976|Bacteroidetes,1I09W@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_8373286_2	1267534.KB906757_gene991	2.242e-23	106.0	COG4948@1|root,COG4948@2|Bacteria,3Y624@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
YHH3_k127_8392737_0	983545.Glaag_3294	1.434e-116	391.0	COG3119@1|root,COG3119@2|Bacteria,1NRGG@1224|Proteobacteria,1SMU4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_8448831_1	1121904.ARBP01000006_gene3699	5.935e-119	390.0	COG3622@1|root,COG3622@2|Bacteria,4PM6P@976|Bacteroidetes,47YPG@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_8448831_3	530564.Psta_3759	1.617e-60	222.0	COG2010@1|root,COG2010@2|Bacteria,2IZQX@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_8448831_0	4565.Traes_7BS_803489ECB.1	6.794e-120	399.0	COG2084@1|root,KOG0409@2759|Eukaryota,37I1B@33090|Viridiplantae,3GEGM@35493|Streptophyta,3KQKR@4447|Liliopsida,3I5RC@38820|Poales	35493|Streptophyta	G	Ketose-bisphosphate aldolase class-II family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537,F_bP_aldolase,NAD_binding_11,NAD_binding_2
YHH3_k127_8448831_4	243090.RB3774	1.428e-34	136.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
YHH3_k127_8448831_2	1178825.ALIH01000004_gene2795	4.519e-112	368.0	COG0673@1|root,COG0673@2|Bacteria,4NJEP@976|Bacteroidetes,1I3KI@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_8498288_2	312153.Pnuc_0319	1.081e-69	247.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,2VHMP@28216|Betaproteobacteria,1K34G@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	ABC transporter	wzt	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
YHH3_k127_8498288_5	1396141.BATP01000035_gene4051	6.594e-47	181.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
YHH3_k127_8498288_3	452637.Oter_3946	6.415e-54	199.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01992,ko:K09690,ko:K09691,ko:K09692	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC2_membrane
YHH3_k127_8498288_4	1128427.KB904821_gene2716	1.708e-49	186.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
YHH3_k127_8498288_0	1128427.KB904821_gene2717	1.92e-113	375.0	28KU8@1|root,2ZCM9@2|Bacteria,1G5AX@1117|Cyanobacteria,1HAQ7@1150|Oscillatoriales	1117|Cyanobacteria	S	STELLO glycosyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	STELLO
YHH3_k127_8498288_1	102125.Xen7305DRAFT_00028570	2.014e-89	320.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1G350@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
YHH3_k127_8498288_6	794903.OPIT5_26745	2.114e-34	140.0	2EMFU@1|root,33F4J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
YHH3_k127_8498288_8	1304872.JAGC01000005_gene1703	6.835e-07	61.0	COG0438@1|root,COG0438@2|Bacteria,1MUYN@1224|Proteobacteria,43F2S@68525|delta/epsilon subdivisions,2X35V@28221|Deltaproteobacteria,2ME5E@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_8498288_7	706587.Desti_3890	5.676e-23	112.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_8519896_1	335992.SAR11_0866	2.657e-40	151.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,4BRA7@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	TIGRFAM TRAP transporter, DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
YHH3_k127_8519896_0	562970.Btus_1285	1.272e-87	304.0	COG1063@1|root,COG1063@2|Bacteria,1U5GN@1239|Firmicutes,4HDDV@91061|Bacilli	91061|Bacilli	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_8527005_1	335543.Sfum_3313	2.579e-114	374.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MQEZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YHH3_k127_8527005_0	335543.Sfum_1400	5.146e-216	683.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2MQ8G@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
YHH3_k127_8534108_0	583355.Caka_1459	2.868e-242	772.0	COG2352@1|root,COG2352@2|Bacteria,46SIN@74201|Verrucomicrobia,3K7TR@414999|Opitutae	414999|Opitutae	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	-	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
YHH3_k127_8534108_1	583355.Caka_1487	7.194e-146	477.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YHH3_k127_8552256_5	382464.ABSI01000011_gene2380	0.0001665	45.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YHH3_k127_8552256_2	316067.Geob_0356	8.43e-39	152.0	COG0494@1|root,COG0494@2|Bacteria,1QXXS@1224|Proteobacteria,43C8Y@68525|delta/epsilon subdivisions,2X7JB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	MutT nudix family protein	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH3_k127_8552256_1	1269813.ATUL01000018_gene2498	1.114e-70	244.0	COG0500@1|root,COG0500@2|Bacteria,1RDRV@1224|Proteobacteria,1S2T5@1236|Gammaproteobacteria,1WYYI@135613|Chromatiales	135613|Chromatiales	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YHH3_k127_8552256_0	945713.IALB_1905	5.2e-130	437.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_8552256_3	452637.Oter_0650	4.793e-11	67.0	COG4726@1|root,COG4726@2|Bacteria,46YMK@74201|Verrucomicrobia,3K9UG@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8587371_5	1396418.BATQ01000185_gene2137	6.831e-36	138.0	COG0673@1|root,COG0673@2|Bacteria,46U2Q@74201|Verrucomicrobia,2IV92@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_8587371_4	391598.FBBAL38_11609	3.651e-89	315.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,DUF4832,GHL6,Glyco_hydro_42,Glyco_hydro_42M
YHH3_k127_8587371_2	756272.Plabr_1509	1.297e-194	618.0	COG3119@1|root,COG3119@2|Bacteria,2J2K3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_8587371_3	886293.Sinac_3870	1.157e-116	394.0	COG3119@1|root,COG3119@2|Bacteria,2IXH3@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_8587371_1	313628.LNTAR_11436	1.659e-195	619.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
YHH3_k127_8587371_0	595460.RRSWK_07139	3.779e-207	649.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_8593468_6	595460.RRSWK_04581	4.757e-21	95.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_8593468_2	344747.PM8797T_26590	4.533e-100	335.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YHH3_k127_8593468_5	1408473.JHXO01000004_gene10	2.234e-23	105.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,4NF2R@976|Bacteroidetes,2FQYA@200643|Bacteroidia	976|Bacteroidetes	HJ	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
YHH3_k127_8593468_1	1121930.AQXG01000001_gene1561	2.32e-159	516.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,4NF2R@976|Bacteroidetes	976|Bacteroidetes	HJ	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
YHH3_k127_8593468_3	478741.JAFS01000001_gene1555	9.144e-72	252.0	28I4Y@1|root,2Z88D@2|Bacteria,46VRF@74201|Verrucomicrobia,37GMA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8593468_0	382464.ABSI01000011_gene2494	9.743e-226	709.0	COG0129@1|root,COG0129@2|Bacteria,46SBY@74201|Verrucomicrobia,2ITPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	Dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
YHH3_k127_8598487_0	1265503.KB905160_gene2780	4.433e-201	642.0	COG3669@1|root,COG3669@2|Bacteria,1NSQC@1224|Proteobacteria,1SM2K@1236|Gammaproteobacteria,2Q7JI@267889|Colwelliaceae	1236|Gammaproteobacteria	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
YHH3_k127_8609161_4	382464.ABSI01000021_gene375	5.449e-34	135.0	COG0168@1|root,COG0168@2|Bacteria,46UGP@74201|Verrucomicrobia,2IVEG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
YHH3_k127_8609161_2	583355.Caka_2125	1.494e-150	489.0	COG0569@1|root,COG0569@2|Bacteria,46TDR@74201|Verrucomicrobia	74201|Verrucomicrobia	C	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
YHH3_k127_8609161_1	452637.Oter_0658	0.0	1094.0	COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia,3K74R@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH3_k127_8609161_0	583355.Caka_0695	0.0	1239.0	COG0187@1|root,COG0187@2|Bacteria,46TW5@74201|Verrucomicrobia,3K7GR@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH3_k127_8609161_3	1396141.BATP01000026_gene1005	8.014e-82	276.0	COG0512@1|root,COG0512@2|Bacteria,46SN1@74201|Verrucomicrobia,2IU46@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YHH3_k127_8633271_6	1123508.JH636445_gene6760	1.333e-20	105.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_8633271_4	118161.KB235922_gene3004	2.545e-81	286.0	2DGT9@1|root,2ZX7M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1961
YHH3_k127_8633271_0	452637.Oter_3766	1.6e-127	448.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_8633271_1	1150600.ADIARSV_4022	2.598e-99	340.0	COG5434@1|root,COG5434@2|Bacteria,4NICS@976|Bacteroidetes,1IVWC@117747|Sphingobacteriia	976|Bacteroidetes	G	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
YHH3_k127_8633271_9	452637.Oter_2906	3.628e-06	61.0	2CC7E@1|root,32M7R@2|Bacteria,46UM2@74201|Verrucomicrobia,3K8H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8633271_2	1304880.JAGB01000002_gene1607	4.316e-93	323.0	COG3119@1|root,COG3119@2|Bacteria,1V6NF@1239|Firmicutes,24MBN@186801|Clostridia	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_8633271_10	1121904.ARBP01000025_gene6117	2.302e-05	57.0	2DBBA@1|root,2Z86Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8633271_3	926566.Terro_4383	2.507e-81	279.0	COG3240@1|root,COG3240@2|Bacteria,3Y779@57723|Acidobacteria,2JM72@204432|Acidobacteriia	204432|Acidobacteriia	I	lipase activity	-	-	-	ko:K21831	-	-	-	-	ko00000	-	-	-	-
YHH3_k127_8633271_8	886377.Murru_3323	1.235e-09	61.0	COG1476@1|root,COG1476@2|Bacteria,4NYE0@976|Bacteroidetes,1IAT3@117743|Flavobacteriia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
YHH3_k127_8633271_5	272624.lpg2369	1.5e-27	115.0	COG3550@1|root,COG3550@2|Bacteria,1NAM8@1224|Proteobacteria,1SD9R@1236|Gammaproteobacteria,1JES5@118969|Legionellales	118969|Legionellales	S	HipA N-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA
YHH3_k127_8633271_7	272624.lpg2379	5.356e-11	66.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,1RPQR@1236|Gammaproteobacteria,1JE69@118969|Legionellales	118969|Legionellales	S	Pfam:HipA_N	-	-	-	-	-	-	-	-	-	-	-	-	HipA_C
YHH3_k127_8641001_1	1330700.JQNC01000003_gene170	2.264e-65	227.0	COG0247@1|root,COG0247@2|Bacteria,1WIQB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
YHH3_k127_8641001_0	530564.Psta_2949	9.92e-159	509.0	COG0075@1|root,COG0075@2|Bacteria,2IYEK@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
YHH3_k127_8641001_2	382464.ABSI01000012_gene2184	4.47e-21	97.0	COG1629@1|root,COG1629@2|Bacteria,46TVI@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_8659838_0	794903.OPIT5_03230	3.377e-160	508.0	COG0174@1|root,COG0174@2|Bacteria,46UNZ@74201|Verrucomicrobia,3K7II@414999|Opitutae	414999|Opitutae	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YHH3_k127_8659838_1	382464.ABSI01000005_gene1181	1.344e-49	182.0	COG3642@1|root,COG3642@2|Bacteria,46ST7@74201|Verrucomicrobia,2IUME@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	lipopolysaccharide core region biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8659838_2	583355.Caka_2746	1.246e-29	121.0	COG0631@1|root,COG0631@2|Bacteria,46S8Z@74201|Verrucomicrobia,3K7IG@414999|Opitutae	414999|Opitutae	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
YHH3_k127_8668165_2	583355.Caka_0906	4.556e-17	92.0	2EWFD@1|root,33PTV@2|Bacteria,46UNG@74201|Verrucomicrobia,3K7NI@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8668165_1	583355.Caka_2162	7.627e-59	209.0	COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia,3K843@414999|Opitutae	414999|Opitutae	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
YHH3_k127_8668165_0	794903.OPIT5_15420	5.543e-68	239.0	COG1082@1|root,COG1082@2|Bacteria,46XIH@74201|Verrucomicrobia,3K8KZ@414999|Opitutae	414999|Opitutae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_8683533_3	382464.ABSI01000002_gene4267	0.00011	54.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K03287,ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
YHH3_k127_8683533_0	278957.ABEA03000126_gene3675	1.49e-141	462.0	COG0513@1|root,COG0513@2|Bacteria,46TUA@74201|Verrucomicrobia,3K7AP@414999|Opitutae	414999|Opitutae	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
YHH3_k127_8683533_2	583355.Caka_2225	7.047e-84	289.0	COG0008@1|root,COG0008@2|Bacteria,46SQ3@74201|Verrucomicrobia,3K7EB@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH3_k127_8683533_1	452637.Oter_2853	9.574e-97	323.0	COG0258@1|root,COG0258@2|Bacteria,46SWB@74201|Verrucomicrobia,3K7JE@414999|Opitutae	414999|Opitutae	L	5'-3' exonuclease	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N
YHH3_k127_8697817_1	694430.Natoc_1313	3.95e-07	61.0	COG0607@1|root,arCOG02021@2157|Archaea,2XZ3E@28890|Euryarchaeota,23WP8@183963|Halobacteria	183963|Halobacteria	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH3_k127_8697817_0	439235.Dalk_1474	1.492e-154	518.0	COG0823@1|root,COG0823@2|Bacteria,1PFY8@1224|Proteobacteria,437BT@68525|delta/epsilon subdivisions,2WURP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8715613_0	929562.Emtol_3309	0.0	1094.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,47N61@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Glyco_hydro_92
YHH3_k127_8715613_2	1122194.AUHU01000001_gene23	2.822e-76	290.0	29765@1|root,2ZUE2@2|Bacteria,1NEEK@1224|Proteobacteria,1SM02@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1961
YHH3_k127_8715613_1	1122605.KB893649_gene3752	1.311e-176	594.0	COG4225@1|root,COG4225@2|Bacteria,4NGSJ@976|Bacteroidetes	976|Bacteroidetes	E	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
YHH3_k127_8715613_3	880070.Cycma_0165	7.986e-40	154.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH3_k127_8715613_4	880070.Cycma_0165	4.221e-38	147.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YHH3_k127_8715613_5	313628.LNTAR_11271	5.254e-09	61.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_872784_2	313628.LNTAR_10971	1.168e-72	252.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_872784_0	344747.PM8797T_14594	1.945e-142	467.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_872784_3	1191523.MROS_1503	1.347e-48	177.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,DUF4437
YHH3_k127_872784_1	616991.JPOO01000003_gene29	1.018e-123	411.0	2DDE1@1|root,2ZHNZ@2|Bacteria,4NNSM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH3_k127_8742990_1	583355.Caka_0699	2.752e-60	211.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
YHH3_k127_8742990_0	595460.RRSWK_02491	3.154e-200	635.0	28JP4@1|root,2Z9F6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8747850_1	452637.Oter_3766	5.32e-46	186.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_8747850_0	382464.ABSI01000012_gene2184	3.718e-121	433.0	COG1629@1|root,COG1629@2|Bacteria,46TVI@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_8756108_1	557598.LHK_02783	2.315e-34	137.0	COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,2VMIW@28216|Betaproteobacteria,2KQYP@206351|Neisseriales	206351|Neisseriales	U	UPF0056 inner membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	MarC
YHH3_k127_8756108_0	1121472.AQWN01000004_gene660	1.212e-127	421.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,260IP@186807|Peptococcaceae	186801|Clostridia	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
YHH3_k127_8756108_3	1449050.JNLE01000003_gene3851	0.0003284	46.0	2AWWH@1|root,31NU1@2|Bacteria,1TZQE@1239|Firmicutes,24VTK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8756108_2	698769.JFBD01000024_gene1884	3.739e-12	66.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli,4C6TS@84406|Virgibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8772115_0	886293.Sinac_1153	5.129e-280	886.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YHH3_k127_8772115_1	886293.Sinac_1154	7.683e-176	557.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YHH3_k127_8816194_7	215803.DB30_6557	1.086e-37	164.0	COG1520@1|root,COG3055@1|root,COG4676@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,COG4676@2|Bacteria,1NZI5@1224|Proteobacteria,43AH4@68525|delta/epsilon subdivisions,2X5X4@28221|Deltaproteobacteria,2Z37E@29|Myxococcales	1224|Proteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Kelch_1,Kelch_4,PKD,UPF0560
YHH3_k127_8816194_4	1396141.BATP01000022_gene333	8.239e-124	432.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8816194_8	1396141.BATP01000022_gene334	1.237e-20	104.0	COG0729@1|root,COG0729@2|Bacteria,46XNN@74201|Verrucomicrobia,2IW9I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8816194_0	1396141.BATP01000022_gene335	4.384e-193	619.0	29RTN@1|root,30CXJ@2|Bacteria,46XB6@74201|Verrucomicrobia,2IV96@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8816194_5	1396141.BATP01000022_gene336	6.746e-109	359.0	2AWPW@1|root,31NKT@2|Bacteria,46WZA@74201|Verrucomicrobia,2IVVN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8816194_9	1121403.AUCV01000054_gene2612	1.629e-05	52.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH3_k127_8816194_6	502025.Hoch_2959	8.577e-38	149.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH3_k127_8816194_3	880070.Cycma_1913	5.29e-139	456.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,47MQK@768503|Cytophagia	976|Bacteroidetes	P	Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_8816194_2	616991.JPOO01000001_gene2852	2.574e-152	489.0	COG4409@1|root,COG4409@2|Bacteria,4PKIP@976|Bacteroidetes,1IJA8@117743|Flavobacteriia,23FZ0@178469|Arenibacter	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
YHH3_k127_8816194_1	314230.DSM3645_24165	3.33e-177	569.0	COG0591@1|root,COG0591@2|Bacteria,2IWSN@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_8816194_10	1121129.KB903359_gene1490	0.0003718	44.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,2FM8T@200643|Bacteroidia,22XNF@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
YHH3_k127_8862310_3	452637.Oter_3511	3.475e-44	168.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_8862310_0	1185876.BN8_02275	9.101e-163	522.0	COG4948@1|root,COG4948@2|Bacteria,4NFH1@976|Bacteroidetes,47MTW@768503|Cytophagia	976|Bacteroidetes	M	Enolase C-terminal domain-like	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
YHH3_k127_8862310_1	313628.LNTAR_13432	6.199e-88	300.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Fer4
YHH3_k127_8864343_1	794903.OPIT5_18660	8.344e-36	144.0	COG1538@1|root,COG1538@2|Bacteria,46T0P@74201|Verrucomicrobia,3K73I@414999|Opitutae	414999|Opitutae	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_8864343_0	338963.Pcar_2244	1.562e-312	969.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43S5E@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YHH3_k127_8873026_2	583355.Caka_2807	1.121e-24	115.0	COG0354@1|root,COG0354@2|Bacteria,46T24@74201|Verrucomicrobia,3K80A@414999|Opitutae	414999|Opitutae	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
YHH3_k127_8873026_0	583355.Caka_2806	7.561e-144	465.0	COG0722@1|root,COG0722@2|Bacteria,46UK5@74201|Verrucomicrobia,3K7BY@414999|Opitutae	414999|Opitutae	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
YHH3_k127_8873026_1	756499.Desde_2474	4.964e-52	190.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,24JNB@186801|Clostridia,261TW@186807|Peptococcaceae	186801|Clostridia	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
YHH3_k127_8873026_3	1197906.CAJQ02000027_gene1525	4.342e-07	53.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JV1X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH3_k127_8877885_1	794903.OPIT5_03035	1.76e-34	144.0	COG5338@1|root,COG5338@2|Bacteria,46XUT@74201|Verrucomicrobia,3K8B8@414999|Opitutae	414999|Opitutae	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
YHH3_k127_8877885_5	794903.OPIT5_03030	2.881e-29	124.0	COG1596@1|root,COG1596@2|Bacteria,46YX8@74201|Verrucomicrobia,3K89Y@414999|Opitutae	414999|Opitutae	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YHH3_k127_8877885_0	583355.Caka_2437	4.846e-197	638.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46V4D@74201|Verrucomicrobia,3K7PF@414999|Opitutae	414999|Opitutae	DM	PFAM lipopolysaccharide biosynthesis protein	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,GNVR,Wzz
YHH3_k127_8877885_4	452637.Oter_1652	4.607e-31	129.0	COG1595@1|root,COG1595@2|Bacteria,46WAM@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YHH3_k127_8877885_10	497964.CfE428DRAFT_0191	4.623e-05	53.0	2C12Z@1|root,2ZUMU@2|Bacteria,46WS3@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8877885_8	246194.CHY_0057	6.219e-11	74.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,42FUD@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH3_k127_8877885_9	1247963.JPHU01000005_gene422	2.733e-06	55.0	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	MA20_31460	-	-	-	-	-	-	-	-	-	-	-	Hpt
YHH3_k127_8877885_6	382464.ABSI01000005_gene1327	9.36e-14	75.0	2DSQH@1|root,33H1Z@2|Bacteria,46TBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8877885_7	1463885.KL578379_gene6089	1.704e-13	74.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria	201174|Actinobacteria	P	Divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
YHH3_k127_8877885_3	583355.Caka_0856	1.082e-31	129.0	COG2197@1|root,COG2197@2|Bacteria,46YM9@74201|Verrucomicrobia,3K9TZ@414999|Opitutae	414999|Opitutae	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
YHH3_k127_8877885_2	452637.Oter_3859	5.533e-32	132.0	COG2804@1|root,COG2804@2|Bacteria,46XYI@74201|Verrucomicrobia,3K8MN@414999|Opitutae	414999|Opitutae	NU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
YHH3_k127_8884040_3	616991.JPOO01000001_gene2850	8.932e-48	175.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_8884040_1	1123242.JH636434_gene4775	7.235e-70	249.0	COG2870@1|root,COG2870@2|Bacteria,2IZ16@203682|Planctomycetes	203682|Planctomycetes	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH3_k127_8884040_0	1267535.KB906767_gene3575	1.949e-120	394.0	COG1915@1|root,COG1915@2|Bacteria,3Y7FB@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8884040_2	1340493.JNIF01000003_gene4381	3.105e-66	235.0	COG0546@1|root,COG0546@2|Bacteria,3Y621@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase
YHH3_k127_8889297_0	1121859.KB890739_gene2734	9.72e-167	541.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,47J9V@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C
YHH3_k127_8889297_1	583355.Caka_0491	6.321e-63	220.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
YHH3_k127_8893617_2	1121468.AUBR01000039_gene1931	0.0003125	55.0	COG1520@1|root,COG2372@1|root,COG1520@2|Bacteria,COG2372@2|Bacteria,1VHS5@1239|Firmicutes	1239|Firmicutes	S	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
YHH3_k127_8893617_1	637905.SVI_1958	9.883e-10	73.0	COG1361@1|root,COG3637@1|root,COG1361@2|Bacteria,COG3637@2|Bacteria,1QVSF@1224|Proteobacteria,1T46K@1236|Gammaproteobacteria,2QEW2@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA,OmpA_membrane
YHH3_k127_8893617_0	1396418.BATQ01000179_gene3142	2.959e-41	177.0	COG1345@1|root,COG1404@1|root,COG1345@2|Bacteria,COG1404@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8
YHH3_k127_8896966_3	583355.Caka_3039	2.243e-14	78.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46UC1@74201|Verrucomicrobia,3K9FB@414999|Opitutae	414999|Opitutae	C	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8896966_0	756272.Plabr_3173	2.14e-168	545.0	COG3119@1|root,COG3119@2|Bacteria,2IXHT@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_8896966_1	1410620.SHLA_5c000060	5.066e-140	462.0	2DBGT@1|root,2Z95U@2|Bacteria,1R2KE@1224|Proteobacteria,2U2FI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8896966_2	556261.HMPREF0240_00986	3.745e-81	301.0	COG3250@1|root,COG3250@2|Bacteria,1UZKP@1239|Firmicutes,24CWJ@186801|Clostridia,36REW@31979|Clostridiaceae	186801|Clostridia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
YHH3_k127_8900265_3	1198452.Jab_2c18680	2.541e-49	195.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2VPBK@28216|Betaproteobacteria,476E0@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
YHH3_k127_8900265_0	929703.KE386491_gene2762	8.009e-220	708.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
YHH3_k127_8900265_5	1396141.BATP01000039_gene1270	6.409e-05	54.0	COG2931@1|root,COG2931@2|Bacteria,46Z9Y@74201|Verrucomicrobia,2IWB4@203494|Verrucomicrobiae	2|Bacteria	Q	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,FG-GAP
YHH3_k127_8900265_4	1089439.KB902240_gene907	1.44e-40	153.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,1S66E@1236|Gammaproteobacteria,460PH@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
YHH3_k127_8900265_1	1191523.MROS_1797	2.243e-76	264.0	COG1521@1|root,COG1521@2|Bacteria	2|Bacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
YHH3_k127_8900265_2	382464.ABSI01000012_gene2069	1.066e-65	230.0	COG0414@1|root,COG0414@2|Bacteria,46SRN@74201|Verrucomicrobia,2ITKC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
YHH3_k127_8902374_4	646529.Desaci_2768	1.829e-11	75.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia,260IT@186807|Peptococcaceae	186801|Clostridia	U	PFAM Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
YHH3_k127_8902374_6	877415.JNJQ01000012_gene605	0.0003092	49.0	COG0517@1|root,COG0517@2|Bacteria,1V7SC@1239|Firmicutes,3VQ91@526524|Erysipelotrichia	526524|Erysipelotrichia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT,CBS
YHH3_k127_8902374_0	404589.Anae109_2406	1.008e-151	490.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2YWI0@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
YHH3_k127_8902374_1	404589.Anae109_2407	2.431e-126	411.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria,2YWQF@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
YHH3_k127_8902374_2	1125863.JAFN01000001_gene560	6.629e-49	181.0	COG2010@1|root,COG2010@2|Bacteria,1QYFZ@1224|Proteobacteria,43CC3@68525|delta/epsilon subdivisions,2WQTQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8902374_3	378806.STAUR_6984	8.035e-14	75.0	COG2863@1|root,COG2863@2|Bacteria,1PFJ2@1224|Proteobacteria,435EU@68525|delta/epsilon subdivisions,2X98T@28221|Deltaproteobacteria,2Z2NE@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YHH3_k127_8902374_5	1487923.DP73_11645	1.829e-08	67.0	COG5373@1|root,COG5373@2|Bacteria,1UUGX@1239|Firmicutes,24EBQ@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
YHH3_k127_8907546_0	857087.Metme_3638	7.224e-147	516.0	COG1305@1|root,COG3209@1|root,COG1305@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RX1G@1236|Gammaproteobacteria,1XG47@135618|Methylococcales	135618|Methylococcales	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YHH3_k127_8907546_1	316274.Haur_2819	2.393e-11	76.0	COG3266@1|root,COG3266@2|Bacteria,2G7UN@200795|Chloroflexi,377BD@32061|Chloroflexia	32061|Chloroflexia	K	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8911073_0	1242864.D187_006227	3.691e-19	101.0	COG2730@1|root,COG4447@1|root,COG2730@2|Bacteria,COG4447@2|Bacteria,1R5GC@1224|Proteobacteria,434P8@68525|delta/epsilon subdivisions,2WZ0H@28221|Deltaproteobacteria,2Z12C@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
YHH3_k127_8911438_1	880073.Calab_0640	2.435e-76	264.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_8911438_0	756272.Plabr_4297	8.332e-118	390.0	COG0673@1|root,COG0673@2|Bacteria,2J0ZB@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA
YHH3_k127_8911438_2	583355.Caka_2937	1.391e-32	131.0	COG3828@1|root,COG3828@2|Bacteria,46V1D@74201|Verrucomicrobia,3KA32@414999|Opitutae	74201|Verrucomicrobia	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
YHH3_k127_8938198_1	583355.Caka_0748	1.181e-79	269.0	COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia,3K7IH@414999|Opitutae	414999|Opitutae	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YHH3_k127_8938198_0	583355.Caka_0749	5.951e-189	600.0	COG0044@1|root,COG0044@2|Bacteria,46S78@74201|Verrucomicrobia,3K7P3@414999|Opitutae	414999|Opitutae	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
YHH3_k127_8938198_2	583355.Caka_0750	4.852e-26	118.0	COG1266@1|root,COG1266@2|Bacteria,46T6D@74201|Verrucomicrobia,3K8IY@414999|Opitutae	414999|Opitutae	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YHH3_k127_8940944_0	278957.ABEA03000157_gene652	4.798e-128	437.0	COG1199@1|root,COG1199@2|Bacteria,46TTB@74201|Verrucomicrobia,3K7UT@414999|Opitutae	414999|Opitutae	KL	HELICc2	-	-	-	-	-	-	-	-	-	-	-	-	DEAD_2,Helicase_C_2
YHH3_k127_8940944_1	382464.ABSI01000002_gene4275	1.689e-75	267.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia,2IU0C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
YHH3_k127_8951465_0	102125.Xen7305DRAFT_00028680	1.174e-69	265.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1G350@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
YHH3_k127_8956652_6	382464.ABSI01000017_gene65	8.589e-09	59.0	COG4773@1|root,COG4773@2|Bacteria,46TWA@74201|Verrucomicrobia	74201|Verrucomicrobia	M	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_8956652_7	56110.Oscil6304_1450	1.017e-06	62.0	2DBBA@1|root,2Z86Y@2|Bacteria,1G1AR@1117|Cyanobacteria,1H8WP@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8956652_5	452637.Oter_2906	2.678e-09	70.0	2CC7E@1|root,32M7R@2|Bacteria,46UM2@74201|Verrucomicrobia,3K8H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8956652_2	1499967.BAYZ01000073_gene2029	2.425e-57	206.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH3_k127_8956652_3	309799.DICTH_1178	9.203e-55	204.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_8956652_0	344747.PM8797T_17624	4.76e-119	400.0	COG3119@1|root,COG3119@2|Bacteria,2J1WZ@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_8956652_1	521460.Athe_2082	1.741e-68	248.0	COG0673@1|root,COG0673@2|Bacteria,1UY90@1239|Firmicutes,24DQA@186801|Clostridia,42GPC@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_8956652_4	314278.NB231_16448	1.962e-12	70.0	2DSUP@1|root,33HGU@2|Bacteria	2|Bacteria	-	-	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8976195_2	243090.RB4017	4.178e-149	479.0	COG3119@1|root,COG3119@2|Bacteria,2IXG7@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_8976195_1	583355.Caka_0642	3.277e-154	499.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
YHH3_k127_8976195_4	1408473.JHXO01000001_gene1962	7.249e-66	239.0	COG0667@1|root,COG0667@2|Bacteria,4PPAM@976|Bacteroidetes,2G14T@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_8976195_3	1250005.PHEL85_2091	1.395e-81	282.0	COG3055@1|root,COG3055@2|Bacteria,4NHHD@976|Bacteroidetes,1HZ82@117743|Flavobacteriia	976|Bacteroidetes	G	Kelch	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_3,Kelch_4,Kelch_6,Malectin,PKD
YHH3_k127_8976195_0	869213.JCM21142_93834	2.199e-185	593.0	COG4225@1|root,COG4225@2|Bacteria,4NGSJ@976|Bacteroidetes,47MHQ@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88,Hepar_II_III
YHH3_k127_9022088_0	880073.Calab_2101	5.882e-197	645.0	COG1361@1|root,COG2911@1|root,COG4935@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG4935@2|Bacteria,2NQI0@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
YHH3_k127_9034048_0	1227352.C173_15024	3.673e-32	143.0	COG1874@1|root,COG3664@1|root,COG3693@1|root,COG5434@1|root,COG1874@2|Bacteria,COG3664@2|Bacteria,COG3693@2|Bacteria,COG5434@2|Bacteria,1UI0G@1239|Firmicutes,4IT73@91061|Bacilli,2778S@186822|Paenibacillaceae	91061|Bacilli	GM	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM9_1,Cadherin-like,SLH
YHH3_k127_9034048_1	1318628.MARLIPOL_08289	7.402e-06	59.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,1R245@1224|Proteobacteria,1T5GA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9042795_1	1123008.KB905698_gene3488	6.762e-122	398.0	COG0654@1|root,COG0654@2|Bacteria,4PPQV@976|Bacteroidetes,2G18G@200643|Bacteroidia,231SC@171551|Porphyromonadaceae	2|Bacteria	CH	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
YHH3_k127_9042795_0	382464.ABSI01000010_gene3747	4.419e-202	667.0	COG4773@1|root,COG4773@2|Bacteria,46ZJN@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_9047180_0	1122931.AUAE01000008_gene4091	4.871e-177	584.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
YHH3_k127_9067264_0	616991.JPOO01000001_gene2850	7.349e-112	370.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_9067264_1	243090.RB8002	1.611e-109	361.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9070622_0	1123399.AQVE01000004_gene2632	1.922e-97	329.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Rhs Element Vgr Protein	vgrG1	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
YHH3_k127_9070622_2	985665.HPL003_11015	6.569e-05	54.0	COG3675@1|root,COG3675@2|Bacteria,1VN9E@1239|Firmicutes,4HS0X@91061|Bacilli,277AZ@186822|Paenibacillaceae	91061|Bacilli	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974,Lipase_3
YHH3_k127_9070622_1	864051.BurJ1DRAFT_1653	1.067e-29	119.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,2VHSN@28216|Betaproteobacteria,1KKD3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpV	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH3_k127_9082394_2	485913.Krac_4241	8.59e-45	164.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2G6K4@200795|Chloroflexi	200795|Chloroflexi	H	phosphoenolpyruvate synthase	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH3_k127_9082394_3	401053.AciPR4_3251	4.313e-36	143.0	COG2318@1|root,COG2318@2|Bacteria,3Y81K@57723|Acidobacteria,2JN5E@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YHH3_k127_9082394_1	768706.Desor_2727	3.854e-79	272.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,265H8@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
YHH3_k127_9082394_0	215803.DB30_6423	4.157e-103	351.0	COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,439SK@68525|delta/epsilon subdivisions,2X55M@28221|Deltaproteobacteria,2Z05C@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH3_k127_9124455_1	595460.RRSWK_04036	3.588e-251	788.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Glyco_hydro_28,Pectate_lyase_3
YHH3_k127_9124455_2	243090.RB1205	4.77e-161	520.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_9124455_3	313628.LNTAR_00440	4.941e-151	492.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_9124455_5	1434325.AZQN01000007_gene3051	2.743e-45	167.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,47MQK@768503|Cytophagia	976|Bacteroidetes	P	Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_9124455_0	595460.RRSWK_04038	5.582e-264	824.0	COG3119@1|root,COG5434@1|root,COG3119@2|Bacteria,COG5434@2|Bacteria,2IX9T@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF4976,Glyco_hydro_28,Pectate_lyase_3,Sulfatase
YHH3_k127_9124455_4	595460.RRSWK_06296	3.037e-85	289.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF1501,FIVAR,Laminin_G_3,Phosphodiest,Sulfatase
YHH3_k127_9125040_1	1396418.BATQ01000183_gene987	4.652e-24	110.0	294ZG@1|root,2ZSCB@2|Bacteria,46WKC@74201|Verrucomicrobia,2IW27@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_3
YHH3_k127_9125040_2	398767.Glov_0067	1.289e-14	79.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
YHH3_k127_9125040_0	382464.ABSI01000013_gene1635	1.063e-31	125.0	COG0667@1|root,COG0667@2|Bacteria,46UF5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_9133424_2	1123296.JQKE01000006_gene770	2.216e-17	97.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,2KQA8@206351|Neisseriales	206351|Neisseriales	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
YHH3_k127_9133424_0	478741.JAFS01000001_gene1830	1.91e-68	250.0	COG0318@1|root,COG0318@2|Bacteria,46T7I@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
YHH3_k127_9133424_1	1173027.Mic7113_2369	1.255e-32	133.0	COG0251@1|root,COG0251@2|Bacteria,1GC91@1117|Cyanobacteria	1117|Cyanobacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9167110_0	504487.JCM19302_1261	3.397e-173	587.0	COG1520@1|root,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,1I4P5@117743|Flavobacteriia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ,PQQ_2,PQQ_3
YHH3_k127_9167110_1	717606.PaecuDRAFT_1824	1.056e-61	244.0	COG1470@1|root,COG3693@1|root,COG5434@1|root,COG1470@2|Bacteria,COG3693@2|Bacteria,COG5434@2|Bacteria,1UIPP@1239|Firmicutes,4ISP9@91061|Bacilli,2775K@186822|Paenibacillaceae	91061|Bacilli	G	PFAM glycoside hydrolase family 10	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Lipase_GDSL_2,Polysacc_deac_1,SLH
YHH3_k127_917400_3	1121904.ARBP01000055_gene491	3.256e-37	147.0	COG2984@1|root,COG2984@2|Bacteria	2|Bacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
YHH3_k127_917400_0	756272.Plabr_2355	6.628e-201	638.0	COG3119@1|root,COG3119@2|Bacteria,2IXHT@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_917400_2	1123401.JHYQ01000025_gene3337	1.721e-44	169.0	COG1443@1|root,COG1443@2|Bacteria,1R9YJ@1224|Proteobacteria,1S6ZT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)	idi	GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0033554,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0050896,GO:0051716,GO:0071704,GO:0090407,GO:1901576	4.1.1.33,5.3.3.2	ko:K01597,ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01121,R01123	RC00453,RC00455	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_4179,iECIAI1_1343.ECIAI1_3008,iECO103_1326.ECO103_3464,iECSP_1301.ECSP_3858,iECs_1301.ECs3761,iEcE24377_1341.EcE24377A_3215,iG2583_1286.G2583_3542,iSFV_1184.SFV_2937,iSF_1195.SF2875,iSFxv_1172.SFxv_3153,iSSON_1240.SSON_3042,iS_1188.S3074,iZ_1308.Z4227	NUDIX
YHH3_k127_917400_1	1121904.ARBP01000030_gene1973	2.342e-91	314.0	2CCP0@1|root,2Z7XN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH3_k127_9203804_1	382464.ABSI01000012_gene2254	1.837e-95	319.0	COG0240@1|root,COG0240@2|Bacteria,46SQJ@74201|Verrucomicrobia,2ITRT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
YHH3_k127_9203804_7	1123400.KB904746_gene1239	1.187e-05	54.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	pilA	-	-	ko:K02650,ko:K02655	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
YHH3_k127_9203804_0	583355.Caka_1193	3.765e-115	385.0	COG0477@1|root,COG2814@2|Bacteria,46U1F@74201|Verrucomicrobia,3K73V@414999|Opitutae	414999|Opitutae	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH3_k127_9203804_2	583355.Caka_1192	4.673e-47	175.0	COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia,3K81B@414999|Opitutae	414999|Opitutae	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YHH3_k127_9203804_5	583355.Caka_1191	2.467e-31	130.0	COG0558@1|root,COG0558@2|Bacteria,46VDE@74201|Verrucomicrobia,3K862@414999|Opitutae	414999|Opitutae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YHH3_k127_9203804_4	452637.Oter_3640	2.975e-35	141.0	COG1267@1|root,COG1267@2|Bacteria,46VNU@74201|Verrucomicrobia,3K86I@414999|Opitutae	414999|Opitutae	I	Phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
YHH3_k127_9203804_3	1031711.RSPO_c00723	3.523e-40	156.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,1K5S0@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
YHH3_k127_9203804_6	862908.BMS_0275	1.874e-27	112.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2MT2V@213481|Bdellovibrionales,2WQ1M@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YHH3_k127_9254269_1	383372.Rcas_3637	1.673e-144	483.0	COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,2G9IT@200795|Chloroflexi	200795|Chloroflexi	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
YHH3_k127_9254269_0	583355.Caka_1407	1.957e-183	585.0	COG0064@1|root,COG0064@2|Bacteria,46S5X@74201|Verrucomicrobia,3K7TB@414999|Opitutae	414999|Opitutae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YHH3_k127_9254269_2	452637.Oter_2360	4.546e-138	446.0	COG0154@1|root,COG0154@2|Bacteria,46SCM@74201|Verrucomicrobia,3K7TV@414999|Opitutae	414999|Opitutae	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH3_k127_9264356_1	926569.ANT_26970	1.451e-13	74.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
YHH3_k127_9264356_0	926569.ANT_26980	2.377e-108	364.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrom_c3_2,Paired_CXXCH_1
YHH3_k127_9279523_7	743722.Sph21_4700	4.91e-86	301.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_9279523_0	595460.RRSWK_04272	1.293e-211	666.0	COG3119@1|root,COG3119@2|Bacteria,2IXBF@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9279523_1	595460.RRSWK_04297	5.011e-208	652.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	galA	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_4_9,CBM_6,DUF1565
YHH3_k127_9279523_13	631362.Thi970DRAFT_00580	9.208e-63	225.0	COG4914@1|root,COG4914@2|Bacteria,1N49U@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
YHH3_k127_9279523_18	794903.OPIT5_21935	1.25e-10	68.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
YHH3_k127_9279523_15	278957.ABEA03000160_gene8	4.925e-44	163.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_9279523_16	595460.RRSWK_04257	1.494e-33	132.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
YHH3_k127_9279523_4	589865.DaAHT2_1405	5.331e-154	496.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42MFI@68525|delta/epsilon subdivisions,2WKXD@28221|Deltaproteobacteria,2MM6V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_9279523_2	795666.MW7_1121	2.622e-171	552.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VNBG@28216|Betaproteobacteria,1K297@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Pfam Sulfatase	betC	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Choline_sulf_C,DUF4976,Sulfatase
YHH3_k127_9279523_11	1449976.KALB_342	1.26e-72	259.0	COG1331@1|root,COG1331@2|Bacteria,2I4AC@201174|Actinobacteria,4E00I@85010|Pseudonocardiales	201174|Actinobacteria	O	Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
YHH3_k127_9279523_6	716928.AJQT01000128_gene5134	7.408e-120	397.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
YHH3_k127_9279523_10	411902.CLOBOL_00919	8.912e-73	254.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,2209V@1506553|Lachnoclostridium	186801|Clostridia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17,4.2.1.18	ko:K01715,ko:K13766	ko00280,ko00650,ko01100,ko01200,map00280,map00650,map01100,map01200	M00036	R02085,R03026	RC00831,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YHH3_k127_9279523_5	545243.BAEV01000073_gene2740	7.688e-149	485.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,36DK7@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
YHH3_k127_9279523_8	1123242.JH636434_gene5547	1.48e-84	287.0	COG3836@1|root,COG3836@2|Bacteria	2|Bacteria	G	2-keto-3-deoxy-L-rhamnonate aldolase activity	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
YHH3_k127_9279523_3	344747.PM8797T_10824	2.244e-156	509.0	COG0591@1|root,COG0591@2|Bacteria,2J2BD@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_9279523_17	794903.OPIT5_15805	3.178e-23	113.0	COG4409@1|root,COG4409@2|Bacteria,46WX2@74201|Verrucomicrobia,3K9Q6@414999|Opitutae	414999|Opitutae	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
YHH3_k127_9279523_14	382464.ABSI01000010_gene3793	1.026e-56	205.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YHH3_k127_9279523_12	278957.ABEA03000203_gene2708	1.876e-68	246.0	COG1609@1|root,COG1609@2|Bacteria,46V4U@74201|Verrucomicrobia,3K980@414999|Opitutae	414999|Opitutae	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
YHH3_k127_9279523_19	1026882.MAMP_01900	1.593e-10	73.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,461F5@72273|Thiotrichales	72273|Thiotrichales	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	-	-	-	-	-	-	-	-	-	PATR
YHH3_k127_9287582_0	382464.ABSI01000006_gene877	2.667e-211	665.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,2IUMH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
YHH3_k127_9287582_1	382464.ABSI01000006_gene876	5.278e-104	346.0	COG1917@1|root,COG4977@1|root,COG1917@2|Bacteria,COG4977@2|Bacteria,46WR3@74201|Verrucomicrobia,2IUSB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9287582_3	870187.Thini_1711	2.675e-38	147.0	COG1848@1|root,COG1848@2|Bacteria,1N8VX@1224|Proteobacteria,1SP0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_9287582_2	583355.Caka_1510	4.138e-40	153.0	COG3012@1|root,COG3012@2|Bacteria,46W94@74201|Verrucomicrobia,3K9ZF@414999|Opitutae	414999|Opitutae	S	SEC-C Motif Domain Protein	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	-
YHH3_k127_9287582_4	583355.Caka_1509	1.973e-24	104.0	COG2827@1|root,COG2827@2|Bacteria,46WFE@74201|Verrucomicrobia	74201|Verrucomicrobia	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
YHH3_k127_9308689_0	583355.Caka_3033	3.746e-170	552.0	COG1331@1|root,COG1331@2|Bacteria,46SEJ@74201|Verrucomicrobia,3K76Y@414999|Opitutae	414999|Opitutae	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
YHH3_k127_9336986_0	880072.Desac_0544	8.691e-308	949.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,2MSJC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	por	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH3_k127_9365657_2	382464.ABSI01000010_gene3747	2.683e-156	533.0	COG4773@1|root,COG4773@2|Bacteria,46ZJN@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_9365657_1	344747.PM8797T_30207	1.397e-172	556.0	COG0591@1|root,COG0591@2|Bacteria,2IWSN@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_9365657_3	1123278.KB893616_gene3408	6.015e-84	308.0	COG3119@1|root,COG3119@2|Bacteria,4NE9D@976|Bacteroidetes,47T9R@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9365657_0	1123248.KB893381_gene1115	1.992e-179	582.0	COG3589@1|root,COG3589@2|Bacteria,4NE7B@976|Bacteroidetes	976|Bacteroidetes	G	Pfam Glycoside hydrolase 97	-	-	-	-	-	-	-	-	-	-	-	-	GH97_C,GH97_N,Glyco_hydro_97
YHH3_k127_9371852_0	1499967.BAYZ01000130_gene2591	3.965e-78	266.0	COG1760@1|root,COG1760@2|Bacteria,2NQRY@2323|unclassified Bacteria	2|Bacteria	E	Serine dehydratase alpha chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
YHH3_k127_9371852_1	1122929.KB908217_gene228	4.132e-11	72.0	COG4188@1|root,COG4188@2|Bacteria,1MW6H@1224|Proteobacteria,2TTRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
YHH3_k127_942621_1	1211819.CALK01000045_gene961	1.837e-09	65.0	28QZ5@1|root,2ZDE0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
YHH3_k127_942621_0	1267535.KB906767_gene4416	2.112e-65	232.0	COG1043@1|root,COG1043@2|Bacteria,3Y33C@57723|Acidobacteria,2JI06@204432|Acidobacteriia	57723|Acidobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_11,Hexapep
YHH3_k127_9429463_0	926569.ANT_26980	2.736e-105	352.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrom_c3_2,Paired_CXXCH_1
YHH3_k127_9429463_1	926569.ANT_26970	8.493e-33	133.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
YHH3_k127_9432378_9	382464.ABSI01000013_gene1773	0.0003284	46.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9432378_7	382464.ABSI01000013_gene1772	1.218e-20	99.0	299RH@1|root,2ZWTR@2|Bacteria,46WTD@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9432378_4	102125.Xen7305DRAFT_00028640	5.761e-60	219.0	COG0500@1|root,COG2226@2|Bacteria,1GQMA@1117|Cyanobacteria,3VNN7@52604|Pleurocapsales	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH3_k127_9432378_0	452637.Oter_2584	8.857e-139	456.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
YHH3_k127_9432378_8	452637.Oter_3126	1.725e-14	77.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
YHH3_k127_9432378_2	452637.Oter_2583	2.305e-83	284.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YHH3_k127_9432378_3	1191523.MROS_2048	1.184e-76	283.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
YHH3_k127_9432378_5	452637.Oter_3657	1.826e-40	165.0	COG2207@1|root,COG2207@2|Bacteria,46YE0@74201|Verrucomicrobia,3K9DW@414999|Opitutae	414999|Opitutae	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
YHH3_k127_9432378_1	452637.Oter_2821	2.426e-99	329.0	COG0755@1|root,COG0755@2|Bacteria,46SIH@74201|Verrucomicrobia,3K7UF@414999|Opitutae	414999|Opitutae	O	PFAM cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
YHH3_k127_9441735_1	1121085.AUCI01000018_gene2434	3.544e-135	447.0	COG3119@1|root,COG3119@2|Bacteria,1V6NF@1239|Firmicutes,4ICAY@91061|Bacilli,1ZF1G@1386|Bacillus	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9441735_2	497964.CfE428DRAFT_0137	5.987e-113	380.0	COG3119@1|root,COG3119@2|Bacteria,46TYX@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9441735_0	595460.RRSWK_00738	3.206e-252	786.0	COG3119@1|root,COG3119@2|Bacteria,2J1TM@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9441942_1	1185876.BN8_03376	2.152e-38	149.0	2BSEF@1|root,32MGE@2|Bacteria,4NK41@976|Bacteroidetes,47USI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9441942_0	583355.Caka_1882	1.345e-74	256.0	COG0560@1|root,COG0560@2|Bacteria,46X2A@74201|Verrucomicrobia,3K7WQ@414999|Opitutae	414999|Opitutae	E	TIGRFAM phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase
YHH3_k127_9458159_0	1034769.KB910518_gene3362	6.407e-25	107.0	COG2931@1|root,COG4733@1|root,COG2931@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF4214,F5_F8_type_C,FTP,MAM,Peptidase_M36
YHH3_k127_9458159_1	1236976.JCM16418_358	4.277e-21	101.0	2E4QH@1|root,32ZJ3@2|Bacteria,1V374@1239|Firmicutes,4I0YF@91061|Bacilli,26VR6@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N_3
YHH3_k127_9458159_2	452637.Oter_2048	1.891e-20	108.0	COG4774@1|root,COG4774@2|Bacteria	452637.Oter_2048|-	P	siderophore transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9461566_0	641524.ADICYQ_0052	3.202e-207	657.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,47N97@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9461566_1	211165.AJLN01000107_gene5683	2.709e-77	265.0	COG1028@1|root,COG1028@2|Bacteria,1G3DE@1117|Cyanobacteria,1JJSE@1189|Stigonemataceae	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH3_k127_9461566_2	742766.HMPREF9455_01612	1.762e-36	145.0	COG4124@1|root,COG4124@2|Bacteria,4NEZG@976|Bacteroidetes,2FPAD@200643|Bacteroidia,22XVD@171551|Porphyromonadaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Glyco_hydro_26
YHH3_k127_9474090_11	452637.Oter_2516	1.937e-08	59.0	COG1381@1|root,COG1381@2|Bacteria,46WI8@74201|Verrucomicrobia,3K8H9@414999|Opitutae	414999|Opitutae	L	Involved in DNA repair and RecF pathway recombination	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9474090_9	871968.DESME_01805	3.141e-22	105.0	2DPEU@1|root,331SS@2|Bacteria,1VE8J@1239|Firmicutes,255XC@186801|Clostridia	186801|Clostridia	S	Golgi phosphoprotein 3 (GPP34)	-	-	-	-	-	-	-	-	-	-	-	-	GPP34
YHH3_k127_9474090_3	382464.ABSI01000005_gene968	7.924e-118	408.0	COG0475@1|root,COG0475@2|Bacteria,46U4K@74201|Verrucomicrobia,2IV1A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C
YHH3_k127_9474090_1	278957.ABEA03000085_gene2576	5.066e-169	536.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,3K759@414999|Opitutae	414999|Opitutae	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH3_k127_9474090_5	583355.Caka_1963	3.994e-78	270.0	COG1792@1|root,COG1792@2|Bacteria,46T2J@74201|Verrucomicrobia,3K7Q6@414999|Opitutae	414999|Opitutae	M	shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
YHH3_k127_9474090_0	583355.Caka_1965	9.442e-174	564.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,3K7FW@414999|Opitutae	414999|Opitutae	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
YHH3_k127_9474090_4	452637.Oter_4603	3.136e-104	370.0	COG1305@1|root,COG1305@2|Bacteria,46T2X@74201|Verrucomicrobia,3K7KB@414999|Opitutae	414999|Opitutae	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,Transglut_core
YHH3_k127_9474090_6	278957.ABEA03000176_gene2870	1.009e-66	241.0	COG1721@1|root,COG1721@2|Bacteria,46VIT@74201|Verrucomicrobia,3K7JA@414999|Opitutae	414999|Opitutae	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YHH3_k127_9474090_7	583355.Caka_2946	6.376e-45	168.0	COG0139@1|root,COG0139@2|Bacteria,46SZA@74201|Verrucomicrobia,3K7YM@414999|Opitutae	414999|Opitutae	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
YHH3_k127_9474090_2	583355.Caka_1183	1.421e-128	419.0	COG0533@1|root,COG0533@2|Bacteria,46UIE@74201|Verrucomicrobia,3K75P@414999|Opitutae	414999|Opitutae	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YHH3_k127_9474090_8	794903.OPIT5_03470	5.881e-38	148.0	COG0596@1|root,COG0596@2|Bacteria,46V2G@74201|Verrucomicrobia,3K86K@414999|Opitutae	414999|Opitutae	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YHH3_k127_9503950_0	756272.Plabr_2968	1.131e-235	738.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase,YHYH
YHH3_k127_9503950_2	880070.Cycma_4159	7.072e-11	65.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18,3.2.1.4	ko:K01179,ko:K01186	ko00500,ko00511,ko00600,ko01100,ko04142,map00500,map00511,map00600,map01100,map04142	-	R04018,R06200,R11307,R11308	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33,GH5,GH9	-	BNR_2,BNR_3,CelD_N,Dockerin_1,Glyco_hydro_9
YHH3_k127_9503950_1	243090.32471045	6.502e-106	349.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9506294_1	583355.Caka_0731	2.503e-63	226.0	COG0703@1|root,COG0703@2|Bacteria,46YZV@74201|Verrucomicrobia,3K80S@414999|Opitutae	414999|Opitutae	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
YHH3_k127_9506294_3	452637.Oter_3874	1.802e-54	194.0	COG1259@1|root,COG1259@2|Bacteria,46SW6@74201|Verrucomicrobia,3K81A@414999|Opitutae	414999|Opitutae	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
YHH3_k127_9506294_0	794903.OPIT5_03090	2.38e-129	421.0	COG0042@1|root,COG0042@2|Bacteria,46TSS@74201|Verrucomicrobia,3K73J@414999|Opitutae	414999|Opitutae	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
YHH3_k127_9506294_2	452637.Oter_0498	3.266e-56	203.0	COG0325@1|root,COG0325@2|Bacteria,46SV2@74201|Verrucomicrobia,3K7XG@414999|Opitutae	414999|Opitutae	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
YHH3_k127_9512310_1	452637.Oter_1384	4.354e-112	373.0	COG1609@1|root,COG1609@2|Bacteria,46UWC@74201|Verrucomicrobia,3K8PW@414999|Opitutae	414999|Opitutae	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI
YHH3_k127_9512310_2	583355.Caka_1610	4.044e-88	297.0	COG1043@1|root,COG1043@2|Bacteria,46SD4@74201|Verrucomicrobia,3K7A9@414999|Opitutae	414999|Opitutae	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
YHH3_k127_9512310_3	583355.Caka_2598	6.078e-73	250.0	COG0231@1|root,COG0231@2|Bacteria,46SQH@74201|Verrucomicrobia,3K7PZ@414999|Opitutae	414999|Opitutae	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YHH3_k127_9512310_0	583355.Caka_1611	8.336e-197	623.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,46SG1@74201|Verrucomicrobia,3K7GH@414999|Opitutae	414999|Opitutae	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
YHH3_k127_9529369_0	1353537.TP2_00585	1.646e-296	976.0	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG4625@1|root,COG4935@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria,COG4935@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,DUF4214,HemolysinCabind,Hint_2
YHH3_k127_9529369_9	755178.Cyan10605_0288	1.481e-55	225.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	5_nucleotid_C,Calx-beta,Exo_endo_phos,HemolysinCabind,LTD
YHH3_k127_9529369_12	344747.PM8797T_03194	4.629e-26	128.0	COG1572@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG4625@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
YHH3_k127_9529369_7	929703.KE386491_gene1938	2.92e-62	217.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,47NPG@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_9529369_5	761193.Runsl_2879	2.395e-99	331.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,47NPG@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_9529369_4	344747.PM8797T_11259	4.146e-105	353.0	COG1082@1|root,COG1082@2|Bacteria,2IY3R@203682|Planctomycetes	203682|Planctomycetes	G	ioli protein	-	-	5.3.99.11	ko:K06606	ko00562,ko01120,map00562,map01120	-	R09952	RC01513	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH3_k127_9529369_11	1123070.KB899256_gene2185	2.25e-46	182.0	COG1052@1|root,COG1052@2|Bacteria,46SAN@74201|Verrucomicrobia,2IWPB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH3_k127_9529369_3	658086.HMPREF0994_00389	8.039e-123	409.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia,27P18@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9529369_8	709032.Sulku_2392	1.337e-55	202.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,42QFJ@68525|delta/epsilon subdivisions,2YRCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.20	ko:K01630	ko00053,map00053	-	R02754,R03277	RC00307,RC00435	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
YHH3_k127_9529369_13	1267600.JFGT01000005_gene2863	1.297e-13	78.0	COG3090@1|root,COG3090@2|Bacteria,1RHYR@1224|Proteobacteria,1S7DI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
YHH3_k127_9529369_6	1305836.AXVE01000011_gene1073	1.712e-92	318.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,4H9WK@91061|Bacilli,26ES0@186818|Planococcaceae	91061|Bacilli	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
YHH3_k127_9529369_10	221109.22778946	3.495e-55	205.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,4HA0S@91061|Bacilli,23KH0@182709|Oceanobacillus	91061|Bacilli	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
YHH3_k127_9529369_1	641524.ADICYQ_2788	1.321e-243	767.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18,3.2.1.4	ko:K01179,ko:K01186	ko00500,ko00511,ko00600,ko01100,ko04142,map00500,map00511,map00600,map01100,map04142	-	R04018,R06200,R11307,R11308	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33,GH5,GH9	-	BNR_2,BNR_3,CelD_N,Dockerin_1,Glyco_hydro_9
YHH3_k127_9529369_2	344747.PM8797T_00157	7.255e-144	476.0	COG3119@1|root,COG3119@2|Bacteria,2J1S4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_9544390_2	1403819.BATR01000053_gene1609	4.413e-40	163.0	COG3119@1|root,COG3119@2|Bacteria,46TNU@74201|Verrucomicrobia,2IUAA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9544390_0	756272.Plabr_3772	6.142e-154	503.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Guanylate_cyc,Peptidase_C14
YHH3_k127_9544390_3	1042376.AFPK01000067_gene836	1.142e-15	78.0	2EWBV@1|root,33PQM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9547726_8	397278.JOJN01000001_gene2801	5.181e-33	133.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4DN5B@85009|Propionibacteriales	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH3_k127_9547726_9	583355.Caka_1409	4.171e-20	93.0	COG0721@1|root,COG0721@2|Bacteria,46TA2@74201|Verrucomicrobia,3K8CA@414999|Opitutae	414999|Opitutae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
YHH3_k127_9547726_3	382464.ABSI01000013_gene1792	5.474e-101	347.0	COG0626@1|root,COG0626@2|Bacteria,46UUN@74201|Verrucomicrobia,2ITMP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
YHH3_k127_9547726_1	583355.Caka_1808	6.116e-158	507.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,3K7IM@414999|Opitutae	414999|Opitutae	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YHH3_k127_9547726_4	452637.Oter_2710	1.351e-65	238.0	COG0438@1|root,COG0438@2|Bacteria,46U8D@74201|Verrucomicrobia,3K8XI@414999|Opitutae	414999|Opitutae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_9547726_7	452637.Oter_4014	1.792e-45	175.0	COG0300@1|root,COG0300@2|Bacteria,46VV4@74201|Verrucomicrobia,3K7WJ@414999|Opitutae	414999|Opitutae	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH3_k127_9547726_6	452637.Oter_4017	1.123e-53	203.0	COG0438@1|root,COG0438@2|Bacteria,46TX1@74201|Verrucomicrobia,3K93H@414999|Opitutae	414999|Opitutae	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_9547726_5	583355.Caka_1740	1.117e-58	212.0	2CAZH@1|root,2Z7RU@2|Bacteria,46V42@74201|Verrucomicrobia,3K7Z0@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
YHH3_k127_9547726_0	583355.Caka_1739	1.1e-322	997.0	COG1053@1|root,COG1053@2|Bacteria,46S7D@74201|Verrucomicrobia,3K754@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH3_k127_9547726_2	583355.Caka_1738	5.182e-111	364.0	COG0479@1|root,COG0479@2|Bacteria,46S82@74201|Verrucomicrobia,3K7PU@414999|Opitutae	414999|Opitutae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
YHH3_k127_9549010_3	290633.GOX0444	1.557e-09	60.0	COG0746@1|root,COG1977@1|root,COG0746@2|Bacteria,COG1977@2|Bacteria,1RKCH@1224|Proteobacteria	1224|Proteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,ThiS
YHH3_k127_9549010_2	1121015.N789_05030	1.615e-34	150.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,1X6F7@135614|Xanthomonadales	135614|Xanthomonadales	H	molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
YHH3_k127_9549010_1	1227484.C471_00340	7.058e-57	218.0	COG0476@1|root,arCOG01676@2157|Archaea,2XTYV@28890|Euryarchaeota,23TM2@183963|Halobacteria	183963|Halobacteria	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
YHH3_k127_9549010_0	452637.Oter_0596	2.533e-117	421.0	COG4773@1|root,COG4773@2|Bacteria,46ZJN@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_9554744_1	1499967.BAYZ01000034_gene1067	1.95e-65	232.0	COG0845@1|root,COG0845@2|Bacteria,2NPBH@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	macA_1	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
YHH3_k127_9554744_3	177437.HRM2_05800	3.609e-27	126.0	COG1538@1|root,COG1538@2|Bacteria,1PYD8@1224|Proteobacteria,42P1Y@68525|delta/epsilon subdivisions,2WKZG@28221|Deltaproteobacteria,2MMSN@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
YHH3_k127_9554744_2	313606.M23134_01323	2.972e-35	141.0	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,47QT5@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_9554744_0	316067.Geob_0075	1.687e-133	445.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2WIZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	phospholipid glycerol acyltransferase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
YHH3_k127_9564254_0	583355.Caka_2442	1.27e-100	352.0	COG1729@1|root,COG1729@2|Bacteria,46TWU@74201|Verrucomicrobia,3K7AZ@414999|Opitutae	414999|Opitutae	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
YHH3_k127_9564254_1	452637.Oter_0242	2.474e-62	221.0	COG0811@1|root,COG0811@2|Bacteria,46SUA@74201|Verrucomicrobia,3K7EH@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH3_k127_9564254_3	583355.Caka_2444	1.884e-12	74.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
YHH3_k127_9564254_2	583355.Caka_2703	5.889e-60	207.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,3K7E9@414999|Opitutae	414999|Opitutae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH3_k127_9566305_3	143224.JQMD01000002_gene1597	9.371e-175	563.0	COG3119@1|root,COG3119@2|Bacteria,4NI6A@976|Bacteroidetes,1HZIK@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9566305_1	756272.Plabr_1705	1.37e-183	586.0	COG3119@1|root,COG3119@2|Bacteria,2IXZS@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_9566305_6	886293.Sinac_1338	1.117e-10	73.0	COG3848@1|root,COG3848@2|Bacteria,2J2BJ@203682|Planctomycetes	203682|Planctomycetes	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9566305_5	1380600.AUYN01000001_gene2799	9.318e-156	517.0	COG3540@1|root,COG3540@2|Bacteria,4NFXQ@976|Bacteroidetes,1HY2S@117743|Flavobacteriia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
YHH3_k127_9566305_0	349741.Amuc_1111	4.2e-255	800.0	COG0129@1|root,COG0129@2|Bacteria,46SBY@74201|Verrucomicrobia,2ITPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	Dehydratase family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
YHH3_k127_9566305_4	1178825.ALIH01000004_gene2828	1.265e-156	507.0	COG1457@1|root,COG1457@2|Bacteria,4NHHC@976|Bacteroidetes,1HX92@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the purine-cytosine permease (2.A.39) family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9566305_2	382464.ABSI01000006_gene770	8.63e-176	554.0	COG4146@1|root,COG4146@2|Bacteria,46UV3@74201|Verrucomicrobia,2ITNB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_9583357_0	314230.DSM3645_06619	6.431e-231	722.0	COG0673@1|root,COG0673@2|Bacteria,2IYHK@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_9583357_1	1340493.JNIF01000003_gene2256	2.093e-59	218.0	COG3828@1|root,COG3828@2|Bacteria,3Y6YX@57723|Acidobacteria	57723|Acidobacteria	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
YHH3_k127_9592237_1	382464.ABSI01000005_gene1080	6.066e-68	236.0	COG3534@1|root,COG3534@2|Bacteria,46UU3@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
YHH3_k127_9592237_0	583355.Caka_2929	1.067e-150	486.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	xylR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_IclR,MarR_2,ROK
YHH3_k127_9600583_4	344747.PM8797T_31588	5.189e-22	98.0	COG0673@1|root,COG0673@2|Bacteria,2IX6I@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_9600583_1	616991.JPOO01000001_gene3609	8.446e-91	317.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1HZWB@117743|Flavobacteriia,23G8X@178469|Arenibacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9600583_0	1042376.AFPK01000062_gene1313	9.636e-299	945.0	COG3537@1|root,COG3537@2|Bacteria	2|Bacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
YHH3_k127_9600583_2	530564.Psta_1917	1.726e-71	273.0	COG4099@1|root,COG4099@2|Bacteria,2IZFN@203682|Planctomycetes	203682|Planctomycetes	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
YHH3_k127_9600583_3	1168034.FH5T_05480	5.575e-50	184.0	COG1453@1|root,COG1453@2|Bacteria,4NGCW@976|Bacteroidetes,2FPG8@200643|Bacteroidia	976|Bacteroidetes	S	Tat pathway signal sequence domain protein	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
YHH3_k127_9603355_0	583355.Caka_2259	1.694e-75	287.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,46TY6@74201|Verrucomicrobia	74201|Verrucomicrobia	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
YHH3_k127_962319_1	1408473.JHXO01000004_gene220	9.198e-27	112.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,2FNEV@200643|Bacteroidia	976|Bacteroidetes	M	Phospholipase, patatin family	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
YHH3_k127_962319_0	768704.Desmer_0311	2.455e-91	309.0	COG0697@1|root,COG0697@2|Bacteria,1V009@1239|Firmicutes,24DF1@186801|Clostridia,264VJ@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH3_k127_962319_4	1122176.KB903537_gene1585	0.0005604	52.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes	976|Bacteroidetes	O	Pfam Proprotein convertase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,P_proprotein,Reprolysin_4
YHH3_k127_962319_2	1408473.JHXO01000015_gene1897	2.608e-23	115.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
YHH3_k127_962319_3	1137281.D778_02055	9.912e-08	64.0	COG3227@1|root,COG3291@1|root,COG4935@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NQ5Q@976|Bacteroidetes	976|Bacteroidetes	E	Fungalysin/Thermolysin Propeptide Motif	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	FTP,PepSY,Peptidase_M36,Peptidase_M4
YHH3_k127_9634598_5	1444309.JAQG01000062_gene33	2.249e-21	95.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,26SE8@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	cysA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_9634598_0	240016.ABIZ01000001_gene769	3.829e-143	486.0	COG4591@1|root,COG4591@2|Bacteria,46Z4Y@74201|Verrucomicrobia,2IVII@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
YHH3_k127_9634598_1	240016.ABIZ01000001_gene770	8.344e-102	353.0	COG5621@1|root,COG5621@2|Bacteria,46STV@74201|Verrucomicrobia,2IVAE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
YHH3_k127_9634598_4	485913.Krac_3447	2.314e-27	123.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,2G71Q@200795|Chloroflexi	200795|Chloroflexi	NU	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,NB-ARC,TPR_10,TPR_12,TPR_7
YHH3_k127_9634598_3	452637.Oter_3143	1.03e-47	183.0	COG1105@1|root,COG1105@2|Bacteria,46SED@74201|Verrucomicrobia,3K8AW@414999|Opitutae	414999|Opitutae	H	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH3_k127_9634598_2	123214.PERMA_0403	1.952e-93	313.0	COG0451@1|root,COG0451@2|Bacteria,2G3NS@200783|Aquificae	200783|Aquificae	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
YHH3_k127_9641451_0	382464.ABSI01000011_gene2592	9.666e-301	943.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
YHH3_k127_9641451_1	382464.ABSI01000012_gene1970	3.519e-215	683.0	COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia,2ITMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
YHH3_k127_9641451_2	452637.Oter_0292	2.504e-42	156.0	COG0772@1|root,COG0772@2|Bacteria,46SQT@74201|Verrucomicrobia,3K7H4@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
YHH3_k127_9645491_0	313628.LNTAR_11361	6.837e-179	567.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_9645491_1	1125863.JAFN01000001_gene3144	8.661e-09	70.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CAP,CW_binding_2,DUF4214,HemolysinCabind
YHH3_k127_9650407_1	880070.Cycma_4030	2.557e-159	511.0	COG1331@1|root,COG1331@2|Bacteria,4NSMA@976|Bacteroidetes	976|Bacteroidetes	O	pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
YHH3_k127_9650407_0	382464.ABSI01000021_gene448	2.233e-241	777.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH3_k127_9650407_2	382464.ABSI01000005_gene1051	1.676e-144	466.0	COG1609@1|root,COG1609@2|Bacteria,46U1E@74201|Verrucomicrobia,2IW3R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	-	-	-	-	-	-	-	-	-	GntR,LacI,Peripla_BP_3
YHH3_k127_9650407_4	583355.Caka_0012	1.094e-29	127.0	COG1451@1|root,COG1451@2|Bacteria,46VW6@74201|Verrucomicrobia,3K7I9@414999|Opitutae	414999|Opitutae	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
YHH3_k127_9650407_3	452637.Oter_3553	1.371e-70	244.0	COG1694@1|root,COG3956@2|Bacteria,46V21@74201|Verrucomicrobia,3K767@414999|Opitutae	414999|Opitutae	S	Nucleotide pyrophosphohydrolase	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
YHH3_k127_9660522_0	382464.ABSI01000005_gene1080	3.951e-172	546.0	COG3534@1|root,COG3534@2|Bacteria,46UU3@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
YHH3_k127_9660522_1	1907.SGLAU_30530	6.785e-16	83.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
YHH3_k127_9664272_14	583355.Caka_0008	7.957e-18	85.0	COG0124@1|root,COG0124@2|Bacteria,46S7Y@74201|Verrucomicrobia,3K76H@414999|Opitutae	414999|Opitutae	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YHH3_k127_9664272_10	1313304.CALK_0635	2.026e-40	161.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH3_k127_9664272_9	1333998.M2A_2219	9.067e-49	196.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U0I3@28211|Alphaproteobacteria,4BRC2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_9,Response_reg,dCache_1
YHH3_k127_9664272_7	8128.ENSONIP00000004410	1.043e-56	207.0	COG0434@1|root,2QUBS@2759|Eukaryota,38EZC@33154|Opisthokonta,3BES3@33208|Metazoa,3D0S4@33213|Bilateria,47ZQG@7711|Chordata,4905V@7742|Vertebrata,49RCN@7898|Actinopterygii	33208|Metazoa	S	Zgc 162297	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
YHH3_k127_9664272_8	1245471.PCA10_17240	2.299e-54	198.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,1YFER@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
YHH3_k127_9664272_2	1121440.AUMA01000020_gene1959	5.231e-95	322.0	COG1092@1|root,COG1092@2|Bacteria,1Q08C@1224|Proteobacteria,42RRW@68525|delta/epsilon subdivisions,2WNY5@28221|Deltaproteobacteria,2MAYH@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
YHH3_k127_9664272_5	382464.ABSI01000005_gene1258	2.323e-66	237.0	COG0697@1|root,COG0697@2|Bacteria,46SR7@74201|Verrucomicrobia	74201|Verrucomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH3_k127_9664272_6	1333998.M2A_2143	3.292e-60	213.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,4BQ8N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YHH3_k127_9664272_1	583355.Caka_2016	2.136e-121	401.0	COG0026@1|root,COG0026@2|Bacteria,46SG7@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
YHH3_k127_9664272_0	583355.Caka_2478	3.091e-177	570.0	COG0318@1|root,COG0318@2|Bacteria,46USM@74201|Verrucomicrobia,3K73F@414999|Opitutae	414999|Opitutae	IQ	AMP-binding enzyme	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
YHH3_k127_9664272_3	398767.Glov_2272	1.058e-93	317.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,42NGH@68525|delta/epsilon subdivisions,2WKS6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-Beta hydroxysteroid dehydrogenase isomerase	-	-	1.1.1.394,1.1.1.412	ko:K21271,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
YHH3_k127_9664272_11	382464.ABSI01000006_gene874	5.22e-24	108.0	COG1595@1|root,COG1595@2|Bacteria,46XM2@74201|Verrucomicrobia,2IW65@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_9664272_4	278957.ABEA03000041_gene2102	4.22e-92	310.0	COG3494@1|root,COG3494@2|Bacteria,46SJ6@74201|Verrucomicrobia,3K77G@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
YHH3_k127_9664272_12	1288484.APCS01000067_gene2696	2.488e-23	101.0	COG0495@1|root,COG0495@2|Bacteria,1WIX9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,Leucyl-specific,tRNA-synt_1,tRNA-synt_1_2
YHH3_k127_968891_1	382464.ABSI01000013_gene1571	4.042e-31	133.0	COG1572@1|root,COG3210@1|root,COG3386@1|root,COG4257@1|root,COG5373@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG4257@2|Bacteria,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	-	-	-	ko:K13277,ko:K15125,ko:K15539	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000,ko01002,ko03110	-	-	-	DUF5011
YHH3_k127_968891_0	382464.ABSI01000013_gene1570	1.002e-152	490.0	COG2114@1|root,COG3899@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,46U27@74201|Verrucomicrobia	74201|Verrucomicrobia	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
YHH3_k127_969879_2	794903.OPIT5_21575	4.097e-56	201.0	COG0345@1|root,COG0345@2|Bacteria,46T4K@74201|Verrucomicrobia,3K7QH@414999|Opitutae	414999|Opitutae	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
YHH3_k127_969879_0	1396141.BATP01000020_gene105	3.365e-321	1021.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,46UMR@74201|Verrucomicrobia,2IU32@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EQ	Hydantoinase B/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
YHH3_k127_969879_1	243090.RB2663	1.478e-207	659.0	COG3119@1|root,COG3119@2|Bacteria,2IWSZ@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
YHH3_k127_969879_3	344747.PM8797T_11811	1.632e-13	70.0	COG1520@1|root,COG1520@2|Bacteria,2J4EP@203682|Planctomycetes	203682|Planctomycetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YHH3_k127_9703464_5	1121405.dsmv_2056	1.555e-48	183.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,42Q4T@68525|delta/epsilon subdivisions,2WK9F@28221|Deltaproteobacteria,2MHXS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9703464_2	1121405.dsmv_2057	1.612e-86	291.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42PYJ@68525|delta/epsilon subdivisions,2WKHY@28221|Deltaproteobacteria,2MJ28@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_9703464_0	1232437.KL661988_gene228	4.342e-106	357.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42N3Y@68525|delta/epsilon subdivisions,2WJFS@28221|Deltaproteobacteria,2MJEA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_9703464_1	1265505.ATUG01000001_gene4787	1.828e-101	344.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42QGA@68525|delta/epsilon subdivisions,2WJYS@28221|Deltaproteobacteria,2MI4W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_9703464_3	1121405.dsmv_2060	5.667e-84	286.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,42MIS@68525|delta/epsilon subdivisions,2WMK7@28221|Deltaproteobacteria,2MJNM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
YHH3_k127_9703464_4	335543.Sfum_2673	8.772e-60	216.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
YHH3_k127_9715318_1	880070.Cycma_3618	1.514e-51	194.0	arCOG10801@1|root,2Z9IC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9715318_0	1521187.JPIM01000188_gene1946	5.141e-61	223.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi,3767C@32061|Chloroflexia	32061|Chloroflexia	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9715318_2	555779.Dthio_PD1267	5.617e-38	155.0	COG0667@1|root,COG0667@2|Bacteria,1R77F@1224|Proteobacteria,42Y4Z@68525|delta/epsilon subdivisions,2WTTZ@28221|Deltaproteobacteria,2MCP4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_9715318_3	1121904.ARBP01000014_gene35	3.896e-12	71.0	COG3540@1|root,COG3540@2|Bacteria,4NFXQ@976|Bacteroidetes,47P4T@768503|Cytophagia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
YHH3_k127_9727676_1	243090.RB1456	1.44e-82	277.0	COG3119@1|root,COG3119@2|Bacteria,2IXBF@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_9727676_0	1347342.BN863_19310	6.594e-176	559.0	2EXP7@1|root,33QYX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9757187_0	349741.Amuc_2167	7.535e-163	527.0	COG0339@1|root,COG0339@2|Bacteria,46TWS@74201|Verrucomicrobia,2ITQT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase family M3	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
YHH3_k127_9757187_1	583355.Caka_1947	3.385e-20	94.0	COG0604@1|root,COG0604@2|Bacteria,46VV3@74201|Verrucomicrobia,3K9E2@414999|Opitutae	414999|Opitutae	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_9770487_0	313628.LNTAR_13632	9.01e-130	430.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9770487_1	382464.ABSI01000017_gene32	9.716e-72	259.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_dep_Rec
YHH3_k127_9780746_4	583355.Caka_0417	7.518e-15	74.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46TZV@74201|Verrucomicrobia,3K897@414999|Opitutae	414999|Opitutae	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
YHH3_k127_9780746_1	1191523.MROS_0341	1.431e-137	449.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YHH3_k127_9780746_0	314230.DSM3645_15810	5.925e-141	458.0	COG1448@1|root,COG1448@2|Bacteria,2IYDZ@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase	-	-	2.6.1.1	ko:K00813	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_9780746_3	382464.ABSI01000005_gene1300	2.01e-33	142.0	COG3137@1|root,COG3137@2|Bacteria,46TU0@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
YHH3_k127_9780746_2	583355.Caka_1787	9.568e-131	431.0	COG0318@1|root,COG0318@2|Bacteria,46SG3@74201|Verrucomicrobia,3K7PG@414999|Opitutae	414999|Opitutae	IQ	AMP-dependent synthetase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
YHH3_k127_9788555_3	382464.ABSI01000010_gene3619	2.373e-50	187.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_C_6,TetR_C_7,TetR_N
YHH3_k127_9788555_1	289376.THEYE_A0114	4.277e-166	531.0	COG0473@1|root,COG0473@2|Bacteria,3J0JQ@40117|Nitrospirae	40117|Nitrospirae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH3_k127_9788555_0	1396141.BATP01000004_gene5795	6.12e-178	583.0	COG1053@1|root,COG1053@2|Bacteria,46S51@74201|Verrucomicrobia,2IVH2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
YHH3_k127_9788555_2	1250006.JHZZ01000001_gene2421	4.153e-107	376.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1HYHN@117743|Flavobacteriia,3VX0E@52959|Polaribacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9788555_5	1550091.JROE01000009_gene348	0.0003485	46.0	2CKYD@1|root,32SD9@2|Bacteria,4NUH2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9789735_4	62928.azo0256	1.923e-05	55.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,2KVVT@206389|Rhodocyclales	206389|Rhodocyclales	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
YHH3_k127_9789735_6	1500897.JQNA01000001_gene6437	0.0009444	49.0	COG2834@1|root,COG2834@2|Bacteria,1N09B@1224|Proteobacteria,2VVGD@28216|Betaproteobacteria,1JZVN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	-	-	-	-	-	-	-	-	-	LolA
YHH3_k127_9789735_0	1396141.BATP01000023_gene628	1.938e-70	248.0	COG0463@1|root,COG0463@2|Bacteria,46UW3@74201|Verrucomicrobia,2IVC7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_9789735_5	932213.SPM24T3_17700	0.0003277	52.0	COG0764@1|root,COG0764@2|Bacteria,1NAA7@1224|Proteobacteria,1SCQV@1236|Gammaproteobacteria,403IN@613|Serratia	1236|Gammaproteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	FabA
YHH3_k127_9789735_1	1304883.KI912532_gene833	7.474e-27	123.0	COG0204@1|root,COG0204@2|Bacteria,1RDN7@1224|Proteobacteria,2VNX6@28216|Betaproteobacteria,2KW8J@206389|Rhodocyclales	206389|Rhodocyclales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
YHH3_k127_9789735_3	1121035.AUCH01000022_gene3232	3.099e-07	61.0	COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2VHP0@28216|Betaproteobacteria,2KUNV@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
YHH3_k127_9789735_2	649349.Lbys_1498	2.959e-19	96.0	COG0304@1|root,COG0304@2|Bacteria,4NE8K@976|Bacteroidetes,47PEB@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH3_k127_9795586_0	314230.DSM3645_04495	6.83e-169	550.0	COG0591@1|root,COG3055@1|root,COG0591@2|Bacteria,COG3055@2|Bacteria,2IX6M@203682|Planctomycetes	203682|Planctomycetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,SSF
YHH3_k127_9795586_2	794903.OPIT5_16865	4.343e-77	271.0	COG1609@1|root,COG1609@2|Bacteria,46V4U@74201|Verrucomicrobia,3K980@414999|Opitutae	414999|Opitutae	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
YHH3_k127_9795586_1	344747.PM8797T_24976	6.393e-134	443.0	COG3119@1|root,COG3119@2|Bacteria,2IX47@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.10.1.1	ko:K01565	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07814	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_9803371_3	382464.ABSI01000007_gene4166	9.574e-21	107.0	COG1629@1|root,COG1629@2|Bacteria,46UNV@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_9803371_0	497964.CfE428DRAFT_6049	9.395e-109	369.0	COG0673@1|root,COG0673@2|Bacteria,46U0A@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_9803371_1	497964.CfE428DRAFT_0965	3.22e-93	319.0	COG1082@1|root,COG1082@2|Bacteria,46UT7@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_9803371_2	756272.Plabr_3306	3.843e-28	121.0	COG3119@1|root,COG3119@2|Bacteria,2IYSH@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9825312_2	583355.Caka_0008	1.567e-97	327.0	COG0124@1|root,COG0124@2|Bacteria,46S7Y@74201|Verrucomicrobia,3K76H@414999|Opitutae	414999|Opitutae	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YHH3_k127_9825312_4	583355.Caka_0007	1.706e-37	143.0	COG0776@1|root,COG0776@2|Bacteria,46T4V@74201|Verrucomicrobia,3K84V@414999|Opitutae	414999|Opitutae	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH3_k127_9825312_0	583355.Caka_0006	7.609e-183	587.0	COG1219@1|root,COG1219@2|Bacteria,46U7E@74201|Verrucomicrobia,3K7VN@414999|Opitutae	414999|Opitutae	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
YHH3_k127_9825312_3	583355.Caka_0005	7.779e-81	275.0	COG0500@1|root,COG2226@2|Bacteria,46STX@74201|Verrucomicrobia,3K7U4@414999|Opitutae	414999|Opitutae	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
YHH3_k127_9825312_1	382464.ABSI01000011_gene3072	1.919e-104	344.0	COG0008@1|root,COG0008@2|Bacteria,46S4X@74201|Verrucomicrobia,2ITW6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
YHH3_k127_9832515_0	156889.Mmc1_0375	6.628e-179	578.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1NZZ9@1224|Proteobacteria,2TUXR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	N	ABC transporter permease	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
YHH3_k127_9832515_3	1121439.dsat_0127	1.57e-36	152.0	2C6D0@1|root,31F07@2|Bacteria,1RHBN@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
YHH3_k127_9832515_1	756272.Plabr_1631	2.195e-63	225.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C
YHH3_k127_9832515_2	886293.Sinac_7584	4.629e-45	172.0	COG0715@1|root,COG0715@2|Bacteria,2IX2Y@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
YHH3_k127_9840867_2	794903.OPIT5_03030	3.211e-18	87.0	COG1596@1|root,COG1596@2|Bacteria,46YX8@74201|Verrucomicrobia,3K89Y@414999|Opitutae	414999|Opitutae	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YHH3_k127_9840867_0	583355.Caka_2437	6.599e-195	632.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46V4D@74201|Verrucomicrobia,3K7PF@414999|Opitutae	414999|Opitutae	DM	PFAM lipopolysaccharide biosynthesis protein	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,GNVR,Wzz
YHH3_k127_9840867_1	452637.Oter_1652	4.72e-30	124.0	COG1595@1|root,COG1595@2|Bacteria,46WAM@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YHH3_k127_9852708_0	1042376.AFPK01000062_gene1342	2.95e-212	668.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1HYHN@117743|Flavobacteriia	976|Bacteroidetes	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9852708_1	497965.Cyan7822_4584	6.681e-37	148.0	COG5434@1|root,COG5434@2|Bacteria,1G03H@1117|Cyanobacteria	1117|Cyanobacteria	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
YHH3_k127_9891545_4	583355.Caka_0705	2.009e-62	217.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_9891545_7	1463917.JODC01000015_gene1752	0.000958	45.0	COG3905@1|root,COG3905@2|Bacteria,2GWKG@201174|Actinobacteria	201174|Actinobacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	vapB43	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944	-	-	-	-	-	-	-	-	-	-	RHH_1
YHH3_k127_9891545_6	743299.Acife_1684	2.561e-38	147.0	COG1848@1|root,COG1848@2|Bacteria,1MZR2@1224|Proteobacteria,1S97Y@1236|Gammaproteobacteria,2NDYN@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	-
YHH3_k127_9891545_3	583355.Caka_0599	3.639e-105	352.0	COG1609@1|root,COG4977@1|root,COG1609@2|Bacteria,COG4977@2|Bacteria,46TZS@74201|Verrucomicrobia,3K85D@414999|Opitutae	414999|Opitutae	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Peripla_BP_3
YHH3_k127_9891545_1	583355.Caka_0459	3.73e-188	596.0	2BXG3@1|root,2Z82R@2|Bacteria,46TKW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
YHH3_k127_9891545_2	583355.Caka_0452	1.919e-130	426.0	COG1638@1|root,COG1638@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctP
YHH3_k127_9891545_5	583355.Caka_0453	8.5e-59	208.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
YHH3_k127_9891545_0	583355.Caka_0454	1.085e-208	655.0	COG1593@1|root,COG1593@2|Bacteria,46TSM@74201|Verrucomicrobia,3KA3P@414999|Opitutae	2|Bacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	dctM	-	-	-	-	-	-	-	-	-	-	-	DctM
YHH3_k127_9908440_0	477974.Daud_0644	4.454e-158	509.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH3_k127_9908440_3	583355.Caka_1318	4.89e-34	132.0	COG0236@1|root,COG0236@2|Bacteria,46VWP@74201|Verrucomicrobia,3K882@414999|Opitutae	414999|Opitutae	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
YHH3_k127_9908440_2	583355.Caka_1319	1.875e-96	323.0	COG1028@1|root,COG1028@2|Bacteria,46SNA@74201|Verrucomicrobia,3K7DI@414999|Opitutae	414999|Opitutae	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH3_k127_9908440_1	583355.Caka_1413	5.08e-122	407.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,46SDG@74201|Verrucomicrobia,3K7G2@414999|Opitutae	414999|Opitutae	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
YHH3_k127_9910417_2	114615.BRADO2181	3.186e-05	46.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Peptidase_C14,Pkinase,WD40
YHH3_k127_9910417_1	1408324.JNJK01000003_gene2577	5.037e-12	67.0	COG4096@1|root,COG4096@2|Bacteria	2|Bacteria	L	type I site-specific deoxyribonuclease activity	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,Helicase_C,ResIII
YHH3_k127_9910417_0	935845.JADQ01000020_gene4166	3.565e-77	275.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YHH3_k127_9911729_0	1123393.KB891327_gene308	4.643e-23	111.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VNH0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
YHH3_k127_9911729_2	1123508.JH636441_gene3204	1.311e-10	62.0	COG1595@1|root,COG1595@2|Bacteria,2J2RR@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YHH3_k127_9911729_1	382464.ABSI01000017_gene106	8.524e-17	94.0	COG1629@1|root,COG1629@2|Bacteria	382464.ABSI01000017_gene106|-	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9925914_3	583355.Caka_1153	1.989e-11	73.0	COG1214@1|root,COG1214@2|Bacteria,46WS7@74201|Verrucomicrobia,3K8JH@414999|Opitutae	414999|Opitutae	O	PFAM Peptidase M22, glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
YHH3_k127_9925914_0	278957.ABEA03000080_gene3205	1.243e-114	381.0	COG0787@1|root,COG0787@2|Bacteria,46UBN@74201|Verrucomicrobia,3K796@414999|Opitutae	414999|Opitutae	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
YHH3_k127_9925914_1	583355.Caka_0411	8.371e-46	170.0	2CKAQ@1|root,34BNJ@2|Bacteria,46WDC@74201|Verrucomicrobia,3K83J@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9925914_2	91464.S7335_4375	2.285e-24	108.0	COG2081@1|root,COG2081@2|Bacteria,1FZZ1@1117|Cyanobacteria,1GZ10@1129|Synechococcus	1117|Cyanobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
YHH3_k127_9938969_2	1117315.AHCA01000017_gene1572	8.382e-116	391.0	COG3119@1|root,COG3119@2|Bacteria,1MX3Z@1224|Proteobacteria,1RSAF@1236|Gammaproteobacteria,2Q4PR@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_9938969_6	382464.ABSI01000011_gene2309	2.424e-38	148.0	COG0640@1|root,COG0640@2|Bacteria,46W0M@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
YHH3_k127_9938969_0	382464.ABSI01000011_gene2310	9.779e-207	652.0	COG0701@1|root,COG0701@2|Bacteria,46XR1@74201|Verrucomicrobia,2IWEA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
YHH3_k127_9938969_8	382464.ABSI01000011_gene2314	2.349e-27	113.0	COG0526@1|root,COG0526@2|Bacteria,46WVU@74201|Verrucomicrobia	74201|Verrucomicrobia	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
YHH3_k127_9938969_9	584708.Apau_0098	4.255e-23	105.0	2DPAK@1|root,33193@2|Bacteria,3TCGH@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9938969_5	1336233.JAEH01000040_gene4258	3.88e-39	154.0	COG4232@1|root,COG4232@2|Bacteria,1QJ3E@1224|Proteobacteria,1TH0Z@1236|Gammaproteobacteria,2QDT4@267890|Shewanellaceae	1236|Gammaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
YHH3_k127_9938969_7	452637.Oter_3669	4.737e-30	125.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
YHH3_k127_9938969_3	1123248.KB893340_gene2679	5.086e-92	310.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1IP66@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methylase involved in ubiquinone menaquinone biosynthesis	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
YHH3_k127_9938969_4	382464.ABSI01000010_gene3774	3.05e-64	222.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
YHH3_k127_9938969_1	1123511.KB905843_gene1011	5.61e-151	484.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,4H2KS@909932|Negativicutes	909932|Negativicutes	P	arsenical-resistance protein	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
YHH3_k127_9938969_10	641524.ADICYQ_2331	3.774e-13	72.0	COG1409@1|root,COG1409@2|Bacteria,4NEQ8@976|Bacteroidetes	976|Bacteroidetes	S	Ser Thr phosphatase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH3_k127_9960019_0	452637.Oter_3018	3.328e-177	564.0	COG0166@1|root,COG0166@2|Bacteria,46SUH@74201|Verrucomicrobia,3K7K9@414999|Opitutae	414999|Opitutae	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
YHH3_k127_9960230_1	335543.Sfum_0780	3.065e-84	303.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,GHL6,Glyco_hydro_42M,Polysacc_deac_1
YHH3_k127_9960230_0	765911.Thivi_1729	0.0	1271.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1WWMA@135613|Chromatiales	135613|Chromatiales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
## 3672 queries scanned
## Total time (seconds): 6.307408571243286
## Rate: 582.17 q/s