## Wed Dec 17 12:29:05 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/YHH3_bin.66.fa -m mmseqs --itype genome -o YHH3_bin.66 --output_dir /data/result/bins/wyx/egg/YHH3_bin.66 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YHH3_k127_10013818_0	471853.Bcav_0209	3.791e-153	491.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH3_k127_10013818_2	1121930.AQXG01000001_gene1487	1.984e-114	376.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
YHH3_k127_10013818_1	382464.ABSI01000011_gene2906	7.634e-125	408.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH3_k127_10013818_3	382464.ABSI01000011_gene2907	8.424e-70	243.0	COG1842@1|root,COG1842@2|Bacteria	2|Bacteria	KT	Phage shock protein A	pspA	GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141	-	ko:K03969	-	-	-	-	ko00000	-	-	-	LRAT,PspA_IM30
YHH3_k127_10013818_5	882.DVU_2986	8.846e-32	128.0	COG1983@1|root,COG1983@2|Bacteria,1PWDN@1224|Proteobacteria,42TA8@68525|delta/epsilon subdivisions,2WPVU@28221|Deltaproteobacteria,2MCNH@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	PspC domain protein	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
YHH3_k127_10013818_4	56110.Oscil6304_3039	9.471e-44	168.0	COG0642@1|root,COG2205@2|Bacteria,1G3AM@1117|Cyanobacteria,1HA0Y@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,cNMP_binding
YHH3_k127_1001687_0	452637.Oter_0897	4.55e-198	637.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,46S6T@74201|Verrucomicrobia,3K7S6@414999|Opitutae	414999|Opitutae	CO	Disulphide bond corrector protein DsbC	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YHH3_k127_1001687_2	555779.Dthio_PD1159	2.284e-10	66.0	COG0664@1|root,COG0664@2|Bacteria,1QZ42@1224|Proteobacteria,42XK7@68525|delta/epsilon subdivisions,2WSIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
YHH3_k127_1001687_1	497964.CfE428DRAFT_5328	1.905e-39	154.0	COG1225@1|root,COG1225@2|Bacteria,46VH1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YHH3_k127_10095574_1	690850.Desaf_0397	4.884e-49	180.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42R8A@68525|delta/epsilon subdivisions,2WM6Z@28221|Deltaproteobacteria,2MGB8@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
YHH3_k127_10095574_0	686340.Metal_0971	1.531e-166	535.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1XH1A@135618|Methylococcales	135618|Methylococcales	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_10161045_0	583355.Caka_1614	0.0	1022.0	COG0058@1|root,COG0058@2|Bacteria,46S5T@74201|Verrucomicrobia,3K731@414999|Opitutae	414999|Opitutae	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
YHH3_k127_10161045_1	1499967.BAYZ01000028_gene1226	2.789e-14	79.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
YHH3_k127_1016286_1	452637.Oter_4553	1.251e-33	132.0	COG1995@1|root,COG1995@2|Bacteria,46SNQ@74201|Verrucomicrobia,3K7JT@414999|Opitutae	414999|Opitutae	C	Belongs to the PdxA family	-	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
YHH3_k127_1016286_0	583355.Caka_0862	5.4e-45	166.0	COG0316@1|root,COG0316@2|Bacteria,46T1T@74201|Verrucomicrobia,3K842@414999|Opitutae	414999|Opitutae	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
YHH3_k127_10164509_3	203275.BFO_0306	4.873e-09	57.0	COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,22VVT@171551|Porphyromonadaceae	976|Bacteroidetes	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
YHH3_k127_10164509_0	1396141.BATP01000025_gene973	8.931e-53	196.0	COG2207@1|root,COG2207@2|Bacteria,46VFS@74201|Verrucomicrobia,2IVVR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
YHH3_k127_10164509_1	583355.Caka_1554	2.47e-34	138.0	COG2839@1|root,COG2839@2|Bacteria,46WB1@74201|Verrucomicrobia,3K8HU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
YHH3_k127_10164509_2	583355.Caka_2714	7.946e-21	104.0	28RXC@1|root,2ZE9F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10178583_1	313628.LNTAR_11361	1.83e-60	211.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_10178583_0	452637.Oter_2975	1.383e-132	436.0	COG0673@1|root,COG0673@2|Bacteria,46UJ9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_10199194_3	278957.ABEA03000085_gene2577	6.962e-36	143.0	COG1466@1|root,COG1466@2|Bacteria,46U09@74201|Verrucomicrobia,3K7M7@414999|Opitutae	414999|Opitutae	L	DNA polymerase III	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
YHH3_k127_10199194_5	550540.Fbal_2933	4.524e-16	85.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1SCRT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
YHH3_k127_10199194_6	1121875.KB907549_gene1753	1.082e-11	68.0	2DN4Q@1|root,32VHC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10199194_8	42565.FP66_14635	5.941e-05	48.0	COG5361@1|root,COG5361@2|Bacteria,1NBVB@1224|Proteobacteria,1SES6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Neurotransmitter-gated ion-channel ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Neur_chan_LBD,Neur_chan_memb
YHH3_k127_10199194_1	583355.Caka_2615	5.311e-84	291.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
YHH3_k127_10199194_4	583355.Caka_1538	7.857e-23	108.0	2FGWI@1|root,348RU@2|Bacteria,46W9R@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
YHH3_k127_10199194_7	1185876.BN8_03376	2.173e-05	48.0	2BSEF@1|root,32MGE@2|Bacteria,4NK41@976|Bacteroidetes,47USI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10199194_0	335543.Sfum_0899	1.54e-191	614.0	COG0490@1|root,COG0569@1|root,COG1226@1|root,COG0490@2|Bacteria,COG0569@2|Bacteria,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria,42NKU@68525|delta/epsilon subdivisions,2WIRH@28221|Deltaproteobacteria,2MRD0@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
YHH3_k127_10199194_2	925409.KI911562_gene1735	7.088e-53	196.0	COG3182@1|root,COG3182@2|Bacteria,4NFK9@976|Bacteroidetes,1IW3I@117747|Sphingobacteriia	976|Bacteroidetes	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
YHH3_k127_10207135_0	583355.Caka_2710	0.0	1528.0	COG0085@1|root,COG0085@2|Bacteria,46S8Q@74201|Verrucomicrobia,3K77T@414999|Opitutae	414999|Opitutae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH3_k127_10207135_1	583355.Caka_2711	2.34e-106	346.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia,3K7EI@414999|Opitutae	414999|Opitutae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH3_k127_10216667_0	525897.Dbac_2951	2.998e-252	788.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2MED6@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YHH3_k127_10242589_0	1283300.ATXB01000001_gene901	2.321e-84	300.0	COG1404@1|root,COG2931@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4935@2|Bacteria,1MU7T@1224|Proteobacteria,1T2VQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OQ	serine protease	avxIA	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind,P_proprotein,Peptidase_S8
YHH3_k127_10248504_0	382464.ABSI01000005_gene1146	4.126e-124	411.0	COG0845@1|root,COG0845@2|Bacteria,46U5P@74201|Verrucomicrobia,2IU9K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YHH3_k127_10248504_1	382464.ABSI01000005_gene1147	1.987e-89	314.0	COG1538@1|root,COG1538@2|Bacteria,46VZS@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_10248504_2	497964.CfE428DRAFT_0077	1.79e-60	224.0	COG1538@1|root,COG1538@2|Bacteria,46T1E@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_10271422_2	1191523.MROS_1797	4.387e-47	174.0	COG1521@1|root,COG1521@2|Bacteria	2|Bacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
YHH3_k127_10271422_0	382464.ABSI01000012_gene2069	3.126e-78	268.0	COG0414@1|root,COG0414@2|Bacteria,46SRN@74201|Verrucomicrobia,2ITKC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
YHH3_k127_10271422_1	1184267.A11Q_2261	8.152e-60	211.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2MSX4@213481|Bdellovibrionales,2WIQK@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
YHH3_k127_10291550_0	1399147.P618_200404	3.515e-25	106.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria,47F3E@766|Rickettsiales	766|Rickettsiales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
YHH3_k127_10291550_2	196490.AUEZ01000008_gene5369	1.239e-12	70.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,2UFXF@28211|Alphaproteobacteria,3K0FC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
YHH3_k127_10291550_4	502025.Hoch_0991	1.324e-05	51.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH3_k127_10291550_3	203122.Sde_0182	1.522e-06	51.0	COG5297@1|root,COG5297@2|Bacteria,1RCUV@1224|Proteobacteria,1S2S4@1236|Gammaproteobacteria,46AGB@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593,Malectin
YHH3_k127_10298758_6	1121352.JHZP01000003_gene1423	7.831e-26	114.0	COG1280@1|root,COG1280@2|Bacteria,1RD4I@1224|Proteobacteria,2VQ25@28216|Betaproteobacteria,2KR7M@206351|Neisseriales	206351|Neisseriales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
YHH3_k127_10298758_4	883.DvMF_0942	4.732e-59	213.0	COG0135@1|root,COG0135@2|Bacteria,1RA5Q@1224|Proteobacteria,42T4S@68525|delta/epsilon subdivisions,2WP9V@28221|Deltaproteobacteria,2MBPM@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the TrpF family	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
YHH3_k127_10298758_3	1173023.KE650771_gene1291	1.953e-66	239.0	COG3380@1|root,COG3380@2|Bacteria,1G34R@1117|Cyanobacteria,1JJY4@1189|Stigonemataceae	1117|Cyanobacteria	S	Flavin containing amine oxidoreductase	-	-	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
YHH3_k127_10298758_0	1123070.KB899259_gene1983	2.424e-123	404.0	COG0276@1|root,COG0276@2|Bacteria,46XCA@74201|Verrucomicrobia,2IVEM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Ferrochelatase	-	-	-	-	-	-	-	-	-	-	-	-	Ferrochelatase
YHH3_k127_10298758_5	583355.Caka_2416	8.748e-49	184.0	COG4137@1|root,COG4137@2|Bacteria,46V7V@74201|Verrucomicrobia,3K7TH@414999|Opitutae	414999|Opitutae	S	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
YHH3_k127_10298758_2	583355.Caka_2415	4.303e-91	310.0	COG0373@1|root,COG0373@2|Bacteria,46SMQ@74201|Verrucomicrobia,3K7CJ@414999|Opitutae	414999|Opitutae	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,Shikimate_DH
YHH3_k127_10298758_1	278957.ABEA03000060_gene3117	1.584e-91	310.0	COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,3K7D5@414999|Opitutae	414999|Opitutae	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
YHH3_k127_10304091_0	583355.Caka_2710	4.101e-206	647.0	COG0085@1|root,COG0085@2|Bacteria,46S8Q@74201|Verrucomicrobia,3K77T@414999|Opitutae	414999|Opitutae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH3_k127_10304091_6	382464.ABSI01000011_gene2683	7.447e-49	177.0	COG0222@1|root,COG0222@2|Bacteria,46SWC@74201|Verrucomicrobia,2IUI8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
YHH3_k127_10304091_5	583355.Caka_2708	1.074e-51	187.0	COG0244@1|root,COG0244@2|Bacteria,46T4Q@74201|Verrucomicrobia,3K7ZE@414999|Opitutae	414999|Opitutae	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
YHH3_k127_10304091_2	452637.Oter_0235	3.6e-81	276.0	COG0081@1|root,COG0081@2|Bacteria,46UQ6@74201|Verrucomicrobia,3K7JU@414999|Opitutae	414999|Opitutae	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
YHH3_k127_10304091_4	583355.Caka_2706	1.918e-61	214.0	COG0080@1|root,COG0080@2|Bacteria,46SPZ@74201|Verrucomicrobia,3K7Z5@414999|Opitutae	414999|Opitutae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
YHH3_k127_10304091_3	382464.ABSI01000011_gene2687	2.543e-79	269.0	COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,2IU6S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
YHH3_k127_10304091_7	583355.Caka_2704	1.547e-19	91.0	COG0690@1|root,COG0690@2|Bacteria,46WU6@74201|Verrucomicrobia,3K8FP@414999|Opitutae	414999|Opitutae	U	Belongs to the SecE SEC61-gamma family	-	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
YHH3_k127_10304091_8	661478.OP10G_0131	2.656e-05	46.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH3_k127_10304091_1	382464.ABSI01000011_gene2689	4.857e-102	333.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,2ITQE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH3_k127_10314932_0	330214.NIDE1987	7.927e-65	226.0	COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,3J13S@40117|Nitrospirae	40117|Nitrospirae	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
YHH3_k127_10316521_2	314230.DSM3645_05530	9.286e-16	87.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,2IYGU@203682|Planctomycetes	203682|Planctomycetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
YHH3_k127_10316521_1	583355.Caka_1305	3.428e-32	130.0	COG1544@1|root,COG1544@2|Bacteria,46WAP@74201|Verrucomicrobia,3K89Z@414999|Opitutae	414999|Opitutae	J	PFAM sigma 54 modulation protein ribosomal protein S30EA	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
YHH3_k127_10316521_0	583355.Caka_1303	1.912e-53	195.0	COG0564@1|root,COG0564@2|Bacteria,46V2B@74201|Verrucomicrobia,3K828@414999|Opitutae	414999|Opitutae	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
YHH3_k127_1035207_2	382464.ABSI01000020_gene232	1.15e-143	470.0	COG4166@1|root,COG4166@2|Bacteria,46TR7@74201|Verrucomicrobia,2IWMV@203494|Verrucomicrobiae	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iECABU_c1320.ECABU_c15240,iECNA114_1301.ECNA114_1414,iECSF_1327.ECSF_1224,iNRG857_1313.NRG857_06385,iUMNK88_1353.UMNK88_1667	SBP_bac_5
YHH3_k127_1035207_4	1123070.KB899255_gene1403	1.446e-47	184.0	COG3528@1|root,COG3528@2|Bacteria,46WUE@74201|Verrucomicrobia,2IUWW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
YHH3_k127_1035207_0	583355.Caka_2974	6.704e-168	544.0	COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia,3K7KZ@414999|Opitutae	414999|Opitutae	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
YHH3_k127_1035207_1	1173264.KI913949_gene2506	7.213e-144	471.0	COG1453@1|root,COG1453@2|Bacteria,1G1CE@1117|Cyanobacteria,1H8XE@1150|Oscillatoriales	1117|Cyanobacteria	S	aldo keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
YHH3_k127_1035207_6	269798.CHU_2040	9.889e-31	141.0	COG3509@1|root,COG3509@2|Bacteria,4NVPN@976|Bacteroidetes	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase_phd
YHH3_k127_1035207_5	269798.CHU_1238	3.261e-31	143.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Dockerin_1,Malectin
YHH3_k127_1035207_3	497965.Cyan7822_0595	6.283e-105	351.0	COG2133@1|root,COG2931@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,1GHTZ@1117|Cyanobacteria,3KJHD@43988|Cyanothece	1117|Cyanobacteria	Q	hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
YHH3_k127_1036752_3	583355.Caka_1473	4.932e-68	238.0	2C6QH@1|root,33V43@2|Bacteria,46V9K@74201|Verrucomicrobia,3K7BV@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1036752_0	452637.Oter_2490	2.533e-126	413.0	COG0167@1|root,COG0167@2|Bacteria,46S5W@74201|Verrucomicrobia,3K7GG@414999|Opitutae	414999|Opitutae	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YHH3_k127_1036752_4	382464.ABSI01000010_gene3638	9.648e-42	157.0	COG0838@1|root,COG0838@2|Bacteria,46T33@74201|Verrucomicrobia,2IUK0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YHH3_k127_1036752_2	382464.ABSI01000005_gene1245	1.673e-72	261.0	2F1IQ@1|root,33UJ5@2|Bacteria,46Z53@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YHH3_k127_1036752_5	583355.Caka_1515	1.782e-28	131.0	COG0457@1|root,COG3107@1|root,COG0457@2|Bacteria,COG3107@2|Bacteria,46WDB@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
YHH3_k127_1036752_1	583355.Caka_1516	3.075e-125	423.0	COG0358@1|root,COG0358@2|Bacteria,46THA@74201|Verrucomicrobia,3K7DW@414999|Opitutae	414999|Opitutae	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_2,Toprim_N,zf-CHC2
YHH3_k127_10375089_4	1042376.AFPK01000067_gene837	1.276e-58	207.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1HZA1@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_10375089_0	391598.FBBAL38_11604	1.305e-245	773.0	COG3345@1|root,COG3345@2|Bacteria	2|Bacteria	G	alpha-galactosidase	rafA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
YHH3_k127_10375089_1	595460.RRSWK_07139	5.384e-231	722.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_10375089_2	313628.LNTAR_11101	1.466e-154	503.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_10375089_3	382464.ABSI01000007_gene4166	6.19e-72	277.0	COG1629@1|root,COG1629@2|Bacteria,46UNV@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_10389468_2	1121439.dsat_2440	1.097e-25	109.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,42SUC@68525|delta/epsilon subdivisions,2WPR4@28221|Deltaproteobacteria,2MAWJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
YHH3_k127_10389468_1	1185876.BN8_05036	6.581e-79	270.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_10389468_0	382464.ABSI01000010_gene3318	1.496e-91	316.0	COG3127@1|root,COG3127@2|Bacteria,46TER@74201|Verrucomicrobia,2IVIW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10395903_0	1121904.ARBP01000006_gene3721	3.718e-106	353.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,47NF5@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Sulfatase
YHH3_k127_10395903_1	452637.Oter_3515	4.843e-47	186.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia,3K9I6@414999|Opitutae	414999|Opitutae	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_10434179_3	264462.Bd3281	2.771e-08	59.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,42NJV@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	COG2211 Na melibiose symporter and related	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
YHH3_k127_10434179_1	1384054.N790_03070	1.543e-65	233.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RYRE@1236|Gammaproteobacteria,1X4DI@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
YHH3_k127_10434179_0	1266908.AQPB01000026_gene2705	6.015e-130	422.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1WWIX@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
YHH3_k127_10434179_2	481448.Minf_0132	4.63e-14	80.0	COG4774@1|root,COG4774@2|Bacteria,46TJX@74201|Verrucomicrobia,37GBK@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	siderophore transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
YHH3_k127_10440058_0	382464.ABSI01000013_gene1762	6.578e-174	561.0	COG0559@1|root,COG0559@2|Bacteria,46TMP@74201|Verrucomicrobia,2ITJC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
YHH3_k127_10440058_1	382464.ABSI01000013_gene1761	1.316e-147	469.0	COG0683@1|root,COG0683@2|Bacteria,46TNV@74201|Verrucomicrobia,2ITGH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_5
YHH3_k127_10444068_2	583355.Caka_1506	5.127e-112	372.0	COG0389@1|root,COG0389@2|Bacteria,46SNK@74201|Verrucomicrobia,3K7SQ@414999|Opitutae	414999|Opitutae	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
YHH3_k127_10444068_1	382464.ABSI01000005_gene1342	8.258e-179	569.0	COG0448@1|root,COG0448@2|Bacteria,46SG2@74201|Verrucomicrobia,2IV7B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
YHH3_k127_10444068_0	583355.Caka_2459	1.285e-267	836.0	COG0449@1|root,COG0449@2|Bacteria,46S94@74201|Verrucomicrobia,3K75B@414999|Opitutae	414999|Opitutae	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YHH3_k127_10444068_3	583355.Caka_2017	3.618e-43	166.0	COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,3K72I@414999|Opitutae	414999|Opitutae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
YHH3_k127_10444993_0	583355.Caka_0776	5.874e-139	451.0	COG0714@1|root,COG0714@2|Bacteria,46SC8@74201|Verrucomicrobia,3K7W0@414999|Opitutae	414999|Opitutae	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YHH3_k127_10444993_1	880073.Calab_2467	3.758e-88	298.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
YHH3_k127_10459793_1	382464.ABSI01000005_gene1235	1.628e-76	270.0	COG1721@1|root,COG1721@2|Bacteria,46X0I@74201|Verrucomicrobia,2IWDP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YHH3_k127_10459793_3	583355.Caka_2946	1.329e-43	162.0	COG0139@1|root,COG0139@2|Bacteria,46SZA@74201|Verrucomicrobia,3K7YM@414999|Opitutae	414999|Opitutae	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
YHH3_k127_10459793_0	583355.Caka_1183	9.112e-131	425.0	COG0533@1|root,COG0533@2|Bacteria,46UIE@74201|Verrucomicrobia,3K75P@414999|Opitutae	414999|Opitutae	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YHH3_k127_10459793_4	96561.Dole_2340	2.358e-43	164.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,42TA9@68525|delta/epsilon subdivisions,2WPHJ@28221|Deltaproteobacteria,2MKC1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
YHH3_k127_10459793_2	452637.Oter_3762	4.102e-69	243.0	COG0596@1|root,COG0596@2|Bacteria,46V2G@74201|Verrucomicrobia,3K86K@414999|Opitutae	414999|Opitutae	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YHH3_k127_10478389_0	452637.Oter_3164	4.896e-118	389.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
YHH3_k127_10478389_1	1127673.GLIP_2180	1.133e-77	269.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,464A0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
YHH3_k127_10488622_4	935837.JAEK01000010_gene58	1.315e-05	51.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,1ZBTG@1386|Bacillus	91061|Bacilli	I	Biotin carboxylase	yngH	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YHH3_k127_10488622_1	1304888.ATWF01000001_gene1216	2.274e-14	81.0	COG4770@1|root,COG4770@2|Bacteria,2GFGE@200930|Deferribacteres	200930|Deferribacteres	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
YHH3_k127_10488622_0	583355.Caka_0597	2.58e-145	486.0	COG0457@1|root,COG0457@2|Bacteria,46UPB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1,TPR_8
YHH3_k127_10494889_2	452637.Oter_3364	2.87e-126	415.0	COG0404@1|root,COG0404@2|Bacteria,46UNP@74201|Verrucomicrobia,3K7HR@414999|Opitutae	414999|Opitutae	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YHH3_k127_10494889_3	546274.EIKCOROL_01408	7.036e-45	165.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2VSD7@28216|Betaproteobacteria,2KRA0@206351|Neisseriales	206351|Neisseriales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
YHH3_k127_10494889_4	583355.Caka_1837	6.194e-23	101.0	COG1862@1|root,COG1862@2|Bacteria,46W10@74201|Verrucomicrobia,3K88F@414999|Opitutae	414999|Opitutae	U	TIGRFAM preprotein translocase, YajC subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
YHH3_k127_10494889_0	583355.Caka_1836	1.733e-258	823.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,3K770@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
YHH3_k127_10494889_1	452637.Oter_3463	2.864e-133	436.0	COG0608@1|root,COG0608@2|Bacteria,46SNV@74201|Verrucomicrobia,3K747@414999|Opitutae	414999|Opitutae	L	exonuclease RecJ	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH3_k127_10522161_0	228410.NE1183	6.771e-226	722.0	COG1404@1|root,COG1404@2|Bacteria,1N6G1@1224|Proteobacteria,2WEPE@28216|Betaproteobacteria,372DX@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YHH3_k127_10522815_1	714943.Mucpa_6741	9.582e-28	115.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,1IPWK@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycoside hydrolase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_106,Glyco_hydro_2_N
YHH3_k127_10522815_0	1408473.JHXO01000014_gene4053	4.666e-134	447.0	COG3250@1|root,COG3250@2|Bacteria,4NGZD@976|Bacteroidetes,2G08E@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
YHH3_k127_10568971_0	794903.OPIT5_28865	2.427e-80	275.0	COG1235@1|root,COG1235@2|Bacteria,46SKU@74201|Verrucomicrobia,3K7X5@414999|Opitutae	414999|Opitutae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
YHH3_k127_10568971_2	583355.Caka_1328	4.859e-42	161.0	COG0262@1|root,COG0262@2|Bacteria,46X6E@74201|Verrucomicrobia,3K9WI@414999|Opitutae	414999|Opitutae	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
YHH3_k127_10568971_1	583355.Caka_1327	6.952e-48	172.0	COG0207@1|root,COG0207@2|Bacteria,46SCY@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
YHH3_k127_10591068_1	1333507.AUTQ01000131_gene467	7.597e-12	67.0	COG0591@1|root,COG0591@2|Bacteria,1MW6E@1224|Proteobacteria,1RXYK@1236|Gammaproteobacteria,2Q5DK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_10591068_0	794903.OPIT5_10425	4.281e-57	213.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529,ko:K03435,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
YHH3_k127_10612905_1	382464.ABSI01000010_gene3491	2.381e-75	261.0	COG4447@1|root,COG4447@2|Bacteria,46VN1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10612905_0	382464.ABSI01000010_gene3492	2.15e-288	898.0	2DBYV@1|root,2ZBXC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10612905_2	382464.ABSI01000010_gene3538	8.79e-66	233.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	asbF	-	4.2.1.118	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R01627	RC00568	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YHH3_k127_10616896_1	382464.ABSI01000007_gene4095	5.455e-43	163.0	COG0679@1|root,COG0679@2|Bacteria,46SPM@74201|Verrucomicrobia,2IUBD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
YHH3_k127_10616896_0	382464.ABSI01000002_gene4368	8.664e-126	408.0	COG0369@1|root,COG0369@2|Bacteria	2|Bacteria	C	hydroxylamine reductase activity	petH	GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464	1.14.13.208,1.18.1.2,1.19.1.1	ko:K00528,ko:K02287,ko:K02641,ko:K15511	ko00195,ko00196,ko00362,ko01100,map00195,map00196,map00362,map01100	-	R09555,R10159	RC01739	ko00000,ko00001,ko00194,ko01000	-	-	iJN678.petH	CpcD,FAD_binding_6,Fer4,NAD_binding_1
YHH3_k127_10618459_3	1396141.BATP01000024_gene771	8.725e-08	61.0	COG2931@1|root,COG2931@2|Bacteria,46Z9Y@74201|Verrucomicrobia,2IWB4@203494|Verrucomicrobiae	2|Bacteria	Q	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,FG-GAP
YHH3_k127_10618459_1	278957.ABEA03000094_gene4715	7.69e-24	104.0	2EGU1@1|root,33AK7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10618459_0	452637.Oter_1808	2.037e-82	289.0	COG2378@1|root,COG2378@2|Bacteria,46VG3@74201|Verrucomicrobia,3K846@414999|Opitutae	414999|Opitutae	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
YHH3_k127_10618459_2	1280706.AUJE01000024_gene278	1.222e-09	59.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,4H4NY@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
YHH3_k127_10624951_3	485916.Dtox_0809	9.009e-81	296.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YHH3_k127_10624951_0	583355.Caka_2234	3.765e-233	732.0	COG0029@1|root,COG0029@2|Bacteria,46SHQ@74201|Verrucomicrobia,3K72T@414999|Opitutae	414999|Opitutae	H	L-aspartate oxidase	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH3_k127_10624951_2	583355.Caka_2233	6.48e-82	282.0	COG0414@1|root,COG0414@2|Bacteria,46SRN@74201|Verrucomicrobia,3K7TI@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
YHH3_k127_10624951_1	382464.ABSI01000011_gene2701	5.665e-200	634.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia,2ITKU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH3_k127_10629404_0	583355.Caka_1761	1.916e-177	572.0	COG1966@1|root,COG1966@2|Bacteria,46V26@74201|Verrucomicrobia,3K9J7@414999|Opitutae	414999|Opitutae	T	PFAM carbon starvation protein CstA	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
YHH3_k127_10629404_1	927658.AJUM01000022_gene1031	3.255e-175	555.0	COG0524@1|root,COG0524@2|Bacteria,4NH8K@976|Bacteroidetes,2FM8P@200643|Bacteroidia,3XIZT@558415|Marinilabiliaceae	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
YHH3_k127_10629404_2	583355.Caka_1760	2.953e-144	469.0	COG0232@1|root,COG0232@2|Bacteria,46UHP@74201|Verrucomicrobia,3K787@414999|Opitutae	414999|Opitutae	F	Deoxyguanosinetriphosphate triphosphohydrolase	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
YHH3_k127_10629404_4	873517.HMPREF1977_1495	4.078e-46	172.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1I1XN@117743|Flavobacteriia,1ERU9@1016|Capnocytophaga	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
YHH3_k127_10629404_3	583355.Caka_1913	1.383e-55	200.0	COG2199@1|root,COG3706@2|Bacteria,46ST0@74201|Verrucomicrobia,3K80V@414999|Opitutae	414999|Opitutae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH3_k127_10637037_2	1403819.BATR01000114_gene3994	1.032e-24	105.0	COG0297@1|root,COG0297@2|Bacteria,46Z3D@74201|Verrucomicrobia,2IUHH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_10637037_0	583355.Caka_1129	8.493e-79	280.0	2A75V@1|root,30W1Q@2|Bacteria,46YTX@74201|Verrucomicrobia,3K77H@414999|Opitutae	414999|Opitutae	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
YHH3_k127_10637037_3	583355.Caka_2439	3.052e-13	73.0	COG0238@1|root,COG0238@2|Bacteria,46ZDM@74201|Verrucomicrobia,3K8HR@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bS18 family	-	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
YHH3_k127_10637037_1	452637.Oter_1598	1.498e-78	279.0	COG0009@1|root,COG0009@2|Bacteria,46UW5@74201|Verrucomicrobia,3K7I8@414999|Opitutae	414999|Opitutae	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
YHH3_k127_10637106_0	1121937.AUHJ01000011_gene2880	3.965e-140	468.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,465WW@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG4166 ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
YHH3_k127_10665515_0	595460.RRSWK_04612	5.761e-201	644.0	28HKI@1|root,2Z7VC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10672727_1	697329.Rumal_1568	2.893e-18	96.0	COG2207@1|root,COG2207@2|Bacteria,1V1FV@1239|Firmicutes,24887@186801|Clostridia,3WJEV@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
YHH3_k127_10672727_0	428125.CLOLEP_00574	6.659e-72	250.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,24AE7@186801|Clostridia,3WP52@541000|Ruminococcaceae	186801|Clostridia	M	Mandelate racemase muconate lactonizing enzyme, N-terminal domain	-	-	4.2.1.5,4.2.1.6	ko:K01683,ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YHH3_k127_1069615_4	794903.OPIT5_18115	3.764e-18	85.0	COG0483@1|root,COG0483@2|Bacteria,46V41@74201|Verrucomicrobia,3K741@414999|Opitutae	414999|Opitutae	G	Inositol monophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
YHH3_k127_1069615_3	382464.ABSI01000007_gene4131	1.236e-73	254.0	COG1207@1|root,COG1207@2|Bacteria,46Z6P@74201|Verrucomicrobia,2IWPS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YHH3_k127_1069615_2	452637.Oter_3012	1.25e-84	291.0	COG0564@1|root,COG0564@2|Bacteria,46SQY@74201|Verrucomicrobia,3K7Y8@414999|Opitutae	414999|Opitutae	G	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
YHH3_k127_1069615_1	382464.ABSI01000010_gene3396	7.347e-96	324.0	COG1816@1|root,COG1816@2|Bacteria,46TKQ@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Adenosine/AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
YHH3_k127_1069615_0	794903.OPIT5_23495	8.051e-170	542.0	COG2309@1|root,COG2309@2|Bacteria,46SAI@74201|Verrucomicrobia,3K7FF@414999|Opitutae	414999|Opitutae	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
YHH3_k127_10718094_2	313596.RB2501_13609	1.215e-69	258.0	COG2905@1|root,COG2905@2|Bacteria,4NDZ8@976|Bacteroidetes,1HWQU@117743|Flavobacteriia	976|Bacteroidetes	T	signal-transduction protein containing cAMP-binding and CBS	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
YHH3_k127_10718094_4	194439.CT1039	2.026e-31	131.0	COG0847@1|root,COG0847@2|Bacteria,1FDW7@1090|Chlorobi	1090|Chlorobi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
YHH3_k127_10718094_7	246194.CHY_0406	0.0002586	47.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,42H31@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
YHH3_k127_10718094_3	382464.ABSI01000013_gene1775	3.132e-41	162.0	COG0564@1|root,COG0564@2|Bacteria,46VMI@74201|Verrucomicrobia	74201|Verrucomicrobia	J	RNA pseudouridylate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
YHH3_k127_10718094_1	583355.Caka_2276	8.893e-74	261.0	2F1FE@1|root,33UG5@2|Bacteria,46V5X@74201|Verrucomicrobia,3K8V2@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10718094_5	583355.Caka_2277	1.579e-13	79.0	COG3166@1|root,COG3166@2|Bacteria,46WNE@74201|Verrucomicrobia,3K9ZH@414999|Opitutae	414999|Opitutae	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10718094_6	583355.Caka_2278	1.284e-08	63.0	2C2W7@1|root,2ZKHB@2|Bacteria,46WXT@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10718094_0	452637.Oter_0639	3.019e-129	431.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	-	-	-	ko:K02453,ko:K02666	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	CarbopepD_reg_2,Secretin,Secretin_N
YHH3_k127_10741342_0	583355.Caka_0861	1.283e-221	697.0	COG0143@1|root,COG0143@2|Bacteria,46SCQ@74201|Verrucomicrobia,3K783@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
YHH3_k127_10741342_1	94122.Shewana3_0285	1.992e-14	75.0	COG0401@1|root,COG0401@2|Bacteria,1N7K3@1224|Proteobacteria,1SGD5@1236|Gammaproteobacteria,2QCT8@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Proteolipid membrane potential modulator	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
YHH3_k127_10741342_2	509635.N824_14135	1.807e-08	57.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1IWY0@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YHH3_k127_10748049_1	382464.ABSI01000010_gene3523	5.64e-43	165.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_10748049_0	452637.Oter_2901	0.0	1154.0	COG4773@1|root,COG4773@2|Bacteria,46TY5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_10748049_2	382464.ABSI01000010_gene3514	1.918e-33	130.0	28MYJ@1|root,2ZB5F@2|Bacteria,46U0W@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10806377_0	756272.Plabr_3306	1.928e-131	430.0	COG3119@1|root,COG3119@2|Bacteria,2IYSH@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_10806377_1	382464.ABSI01000010_gene3494	4.06e-117	386.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	1.1.1.396	ko:K11337	ko00860,ko01110,map00860,map01110	-	R09055	RC01377	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_10806377_2	382464.ABSI01000010_gene3493	1.859e-84	291.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_10813430_0	382464.ABSI01000002_gene4372	1.745e-139	447.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	rnfD	-	1.6.5.8	ko:K00347,ko:K03614	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
YHH3_k127_10813430_3	382464.ABSI01000002_gene4371	1.344e-74	258.0	COG4659@1|root,COG4659@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
YHH3_k127_10813430_1	382464.ABSI01000002_gene4370	4.087e-103	339.0	COG4660@1|root,COG4660@2|Bacteria	2|Bacteria	C	electron transport chain	rnfE	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944	2.3.1.243,4.2.99.18	ko:K02560,ko:K03613,ko:K10773	ko00540,ko01100,ko03410,map00540,map01100,map03410	M00060	R05075	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005,ko03400	-	-	-	Rnf-Nqr
YHH3_k127_10813430_2	382464.ABSI01000002_gene4369	1.385e-95	319.0	COG4657@1|root,COG4657@2|Bacteria	2|Bacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
YHH3_k127_10819724_0	349124.Hhal_0066	1.21e-24	117.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1141@1|root,COG1144@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1141@2|Bacteria,COG1144@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1WX9H@135613|Chromatiales	135613|Chromatiales	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH3_k127_10819724_1	1033802.SSPSH_002754	4.792e-06	57.0	COG3210@1|root,COG3210@2|Bacteria,1R8UF@1224|Proteobacteria	1224|Proteobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP
YHH3_k127_10826062_1	382464.ABSI01000016_gene653	9.369e-147	476.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,2ITG7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YHH3_k127_10826062_0	583355.Caka_2581	7.934e-148	483.0	COG1007@1|root,COG1007@2|Bacteria,46UXV@74201|Verrucomicrobia,3K7C5@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YHH3_k127_10826062_3	557599.MKAN_09185	1.913e-19	94.0	COG1487@1|root,COG1487@2|Bacteria,2GYEI@201174|Actinobacteria,23DTM@1762|Mycobacteriaceae	201174|Actinobacteria	S	PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
YHH3_k127_10826062_2	382464.ABSI01000012_gene2070	2.203e-47	173.0	COG0413@1|root,COG0413@2|Bacteria,46SPN@74201|Verrucomicrobia,2IU4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
YHH3_k127_10839237_2	794903.OPIT5_13850	1.031e-29	120.0	COG0006@1|root,COG0006@2|Bacteria,46SKG@74201|Verrucomicrobia,3K72M@414999|Opitutae	414999|Opitutae	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH3_k127_10839237_0	794903.OPIT5_01655	2.239e-214	685.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia,3KA2J@414999|Opitutae	414999|Opitutae	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YHH3_k127_10839237_1	583355.Caka_0250	1.576e-37	147.0	COG0847@1|root,COG0847@2|Bacteria,46VEF@74201|Verrucomicrobia,3K7YC@414999|Opitutae	414999|Opitutae	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	-
YHH3_k127_10908209_0	1496688.ER33_14285	5.737e-178	571.0	COG0399@1|root,COG0399@2|Bacteria,1G36Q@1117|Cyanobacteria,22TGZ@167375|Cyanobium	1117|Cyanobacteria	M	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
YHH3_k127_10908209_1	583355.Caka_0401	3.85e-23	102.0	COG0451@1|root,COG0451@2|Bacteria,46UP7@74201|Verrucomicrobia,3K999@414999|Opitutae	414999|Opitutae	GM	Polysaccharide biosynthesis protein	-	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
YHH3_k127_10916796_0	452637.Oter_1787	7.115e-78	274.0	COG1929@1|root,COG1929@2|Bacteria,46TGW@74201|Verrucomicrobia,3K730@414999|Opitutae	414999|Opitutae	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
YHH3_k127_10916796_1	583355.Caka_1734	2.871e-13	70.0	COG3216@1|root,COG3216@2|Bacteria,46WES@74201|Verrucomicrobia,3K9VH@414999|Opitutae	414999|Opitutae	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
YHH3_k127_1092355_0	452637.Oter_2009	3.28e-232	731.0	COG0326@1|root,COG0326@2|Bacteria,46U76@74201|Verrucomicrobia,3K7PC@414999|Opitutae	414999|Opitutae	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
YHH3_k127_1092355_1	574376.BAMA_22005	0.0003874	48.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
YHH3_k127_10926458_7	1123288.SOV_4c05420	2.466e-06	59.0	COG0810@1|root,COG0810@2|Bacteria,1VN7X@1239|Firmicutes,4H6CY@909932|Negativicutes	909932|Negativicutes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH3_k127_10926458_0	763034.HMPREF9446_03689	3.097e-280	892.0	COG2605@1|root,COG2605@2|Bacteria,4NHF2@976|Bacteroidetes,2FMWG@200643|Bacteroidia,4AP97@815|Bacteroidaceae	976|Bacteroidetes	S	GHMP kinase, N-terminal domain protein	fkp	-	-	-	-	-	-	-	-	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
YHH3_k127_10926458_4	240016.ABIZ01000001_gene4321	2.035e-45	171.0	COG0637@1|root,COG0637@2|Bacteria,46VM3@74201|Verrucomicrobia,2IUCI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH3_k127_10926458_5	656519.Halsa_0439	1.101e-29	136.0	COG2202@1|root,COG3437@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG3852@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,3WBCN@53433|Halanaerobiales	186801|Clostridia	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HD,HD_5,PAS,PAS_3,PAS_4,PAS_9
YHH3_k127_10926458_6	278957.ABEA03000174_gene3411	1.516e-22	103.0	COG2197@1|root,COG2197@2|Bacteria,46T2B@74201|Verrucomicrobia,3K7X9@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_10926458_1	452637.Oter_0810	2.358e-126	419.0	28H6T@1|root,2Z7J4@2|Bacteria,46UBR@74201|Verrucomicrobia,3K7P2@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_10926458_2	583355.Caka_1537	4.434e-97	329.0	COG1253@1|root,COG1253@2|Bacteria,46UX9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
YHH3_k127_10926458_3	382464.ABSI01000010_gene3303	6.515e-48	175.0	COG0682@1|root,COG0682@2|Bacteria,46SSY@74201|Verrucomicrobia,2IU4I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
YHH3_k127_10934343_2	382464.ABSI01000016_gene647	2.533e-206	651.0	COG1034@1|root,COG1034@2|Bacteria,46S6S@74201|Verrucomicrobia,2ITJ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
YHH3_k127_10934343_0	583355.Caka_2572	7.215e-221	694.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia,3K7HM@414999|Opitutae	414999|Opitutae	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
YHH3_k127_10934343_3	382464.ABSI01000016_gene645	2.822e-64	224.0	COG1905@1|root,COG1905@2|Bacteria,46VMZ@74201|Verrucomicrobia,2IU8F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YHH3_k127_10934343_1	583355.Caka_2570	1.829e-206	647.0	COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,3K7QV@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
YHH3_k127_10951534_2	452637.Oter_3616	5.605e-20	93.0	COG3842@1|root,COG3842@2|Bacteria,46SFH@74201|Verrucomicrobia,3K7SS@414999|Opitutae	414999|Opitutae	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran
YHH3_k127_10951534_0	278957.ABEA03000157_gene663	4.472e-161	526.0	COG1840@1|root,COG1840@2|Bacteria,46SF5@74201|Verrucomicrobia,3K7IW@414999|Opitutae	414999|Opitutae	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
YHH3_k127_10951534_1	439235.Dalk_2237	6.487e-40	156.0	COG0477@1|root,COG2814@2|Bacteria,1R518@1224|Proteobacteria,43B4F@68525|delta/epsilon subdivisions,2WIQ4@28221|Deltaproteobacteria,2MIEM@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH3_k127_1098207_0	1094980.Mpsy_0698	9.667e-270	839.0	COG0058@1|root,arCOG01421@2157|Archaea,2XV8J@28890|Euryarchaeota,2NACZ@224756|Methanomicrobia	224756|Methanomicrobia	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
YHH3_k127_1098207_1	269797.Mbar_A0175	6.519e-147	480.0	COG0469@1|root,arCOG04120@2157|Archaea,2XU34@28890|Euryarchaeota,2N9DV@224756|Methanomicrobia	224756|Methanomicrobia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
YHH3_k127_1098207_2	1159870.KB907784_gene553	4.26e-55	196.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,3T708@506|Alcaligenaceae	28216|Betaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
YHH3_k127_11039510_0	330214.NIDE3921	3.897e-119	390.0	29TFP@1|root,30ENV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YHH3_k127_11052959_0	382464.ABSI01000005_gene1222	1.017e-237	744.0	COG4799@1|root,COG4799@2|Bacteria,46Z6F@74201|Verrucomicrobia,2IWPP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YHH3_k127_11052959_1	583355.Caka_0800	4.262e-60	210.0	COG0346@1|root,COG0346@2|Bacteria,46VJH@74201|Verrucomicrobia,3K82H@414999|Opitutae	414999|Opitutae	E	Glyoxalase-like domain	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
YHH3_k127_11052959_2	1499967.BAYZ01000074_gene2193	3.9e-57	210.0	COG1884@1|root,COG1884@2|Bacteria,2NQRE@2323|unclassified Bacteria	2|Bacteria	I	Methylmalonyl-CoA mutase	mutA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944	2.7.7.7,5.4.99.2,5.4.99.63	ko:K01847,ko:K03763,ko:K14447	ko00230,ko00240,ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,ko03030,ko03430,ko03440,map00230,map00240,map00280,map00630,map00640,map00720,map01100,map01120,map01200,map03030,map03430,map03440	M00260,M00373,M00376,M00741	R00375,R00376,R00377,R00378,R00833,R09292	RC00395,RC02795,RC02835	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	MM_CoA_mutase
YHH3_k127_11071213_0	583355.Caka_1296	2.518e-281	878.0	COG0034@1|root,COG0034@2|Bacteria,46UIJ@74201|Verrucomicrobia,3K7AM@414999|Opitutae	414999|Opitutae	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
YHH3_k127_11071213_1	626939.HMPREF9443_00198	4.157e-134	439.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,4H2JU@909932|Negativicutes	909932|Negativicutes	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
YHH3_k127_11110639_0	583355.Caka_0740	1.026e-294	914.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia,3K7JS@414999|Opitutae	414999|Opitutae	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
YHH3_k127_11110639_1	583355.Caka_0731	0.0008264	43.0	COG0703@1|root,COG0703@2|Bacteria,46YZV@74201|Verrucomicrobia,3K80S@414999|Opitutae	414999|Opitutae	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
YHH3_k127_11113249_0	1396141.BATP01000022_gene333	1.812e-182	578.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11113249_3	1380370.JIBA01000012_gene3559	9.105e-15	83.0	2FAXM@1|root,3434G@2|Bacteria,2IRD0@201174|Actinobacteria,4FHI7@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11113249_1	452637.Oter_1983	8.45e-142	459.0	COG1132@1|root,COG1132@2|Bacteria,46UY5@74201|Verrucomicrobia,3K7GK@414999|Opitutae	414999|Opitutae	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH3_k127_11130639_3	583355.Caka_1811	4.335e-09	58.0	COG1387@1|root,COG1387@2|Bacteria,46U67@74201|Verrucomicrobia,3K8DP@414999|Opitutae	414999|Opitutae	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
YHH3_k127_11130639_4	1385935.N836_05280	1.903e-08	66.0	COG2374@1|root,COG2931@1|root,COG3391@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0YK@1117|Cyanobacteria,1HI6M@1150|Oscillatoriales	1117|Cyanobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Exo_endo_phos,HemolysinCabind,Phytase-like
YHH3_k127_11130639_0	382464.ABSI01000002_gene4262	2.09e-224	710.0	COG0733@1|root,COG0733@2|Bacteria,46XCF@74201|Verrucomicrobia,2IVFD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
YHH3_k127_11130639_1	452637.Oter_1910	1.079e-123	407.0	COG2317@1|root,COG2317@2|Bacteria,46TJB@74201|Verrucomicrobia,3K7EU@414999|Opitutae	414999|Opitutae	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
YHH3_k127_11132595_2	1120999.JONM01000009_gene352	4.839e-34	150.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,2W1GY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
YHH3_k127_11132595_0	583355.Caka_0008	1.165e-151	492.0	COG0124@1|root,COG0124@2|Bacteria,46S7Y@74201|Verrucomicrobia,3K76H@414999|Opitutae	414999|Opitutae	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YHH3_k127_11132595_1	583355.Caka_0007	2.261e-37	143.0	COG0776@1|root,COG0776@2|Bacteria,46T4V@74201|Verrucomicrobia,3K84V@414999|Opitutae	414999|Opitutae	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH3_k127_11132595_3	204669.Acid345_2979	0.0007747	43.0	COG1680@1|root,COG1680@2|Bacteria,3Y3T0@57723|Acidobacteria,2JHSK@204432|Acidobacteriia	204432|Acidobacteriia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH3_k127_11134622_0	1499967.BAYZ01000068_gene1921	1.611e-126	413.0	COG0226@1|root,COG0226@2|Bacteria,2NQMD@2323|unclassified Bacteria	2|Bacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
YHH3_k127_11134622_1	583355.Caka_2256	2.414e-106	358.0	COG3746@1|root,COG3746@2|Bacteria,46T78@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
YHH3_k127_11134622_2	203122.Sde_3419	8.337e-27	120.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748,OmpA
YHH3_k127_11134628_1	756499.Desde_2474	1.549e-51	186.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,24JNB@186801|Clostridia,261TW@186807|Peptococcaceae	186801|Clostridia	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
YHH3_k127_11134628_0	583355.Caka_2806	4.527e-137	445.0	COG0722@1|root,COG0722@2|Bacteria,46UK5@74201|Verrucomicrobia,3K7BY@414999|Opitutae	414999|Opitutae	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
YHH3_k127_11134628_2	583355.Caka_2807	2.167e-15	85.0	COG0354@1|root,COG0354@2|Bacteria,46T24@74201|Verrucomicrobia,3K80A@414999|Opitutae	414999|Opitutae	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
YHH3_k127_11139037_1	290317.Cpha266_1487	4.353e-09	59.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH3_k127_11139037_2	1121406.JAEX01000005_gene2887	4.247e-08	56.0	COG3058@1|root,COG3058@2|Bacteria,1NK06@1224|Proteobacteria,42VNJ@68525|delta/epsilon subdivisions,2WS9J@28221|Deltaproteobacteria,2M8KA@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Necessary for formate dehydrogenase activity	fdhE	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
YHH3_k127_11139037_0	977880.pRALTA_0023	3.254e-17	91.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
YHH3_k127_11154832_1	278963.ATWD01000002_gene445	7.136e-69	258.0	COG4225@1|root,COG4225@2|Bacteria,3Y3V1@57723|Acidobacteria,2JIHU@204432|Acidobacteriia	204432|Acidobacteriia	S	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
YHH3_k127_11154832_2	414684.RC1_2258	1.982e-09	64.0	COG2944@1|root,COG2944@2|Bacteria,1NH2C@1224|Proteobacteria,2UK4P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
YHH3_k127_11154832_0	595460.RRSWK_04037	7.814e-92	308.0	COG3119@1|root,COG3119@2|Bacteria,2IXIE@203682|Planctomycetes	2|Bacteria	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
YHH3_k127_11176325_0	426114.THI_3255	1.077e-51	189.0	COG0671@1|root,COG0671@2|Bacteria,1RFUF@1224|Proteobacteria,2VRMF@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
YHH3_k127_11176325_1	1552758.NC00_08605	1.01e-42	166.0	COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,1SF2E@1236|Gammaproteobacteria,1X35Y@135614|Xanthomonadales	135614|Xanthomonadales	G	esterase	nodB	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
YHH3_k127_11176325_2	1134474.O59_003370	0.0001815	45.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,1FIHV@10|Cellvibrio	1236|Gammaproteobacteria	C	NAD(P)-binding Rossmann-like domain	pltA	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
YHH3_k127_11178840_0	243090.RB5097	6.348e-91	305.0	COG0177@1|root,COG0177@2|Bacteria,2IYYT@203682|Planctomycetes	203682|Planctomycetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
YHH3_k127_11178840_3	370438.PTH_1136	1.558e-10	72.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,2600P@186807|Peptococcaceae	186801|Clostridia	U	Type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH3_k127_11178840_1	1396141.BATP01000028_gene2291	8.887e-59	208.0	COG0252@1|root,COG0252@2|Bacteria,46VQ4@74201|Verrucomicrobia,2IWJ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EJ	Asparaginase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase
YHH3_k127_11178840_2	382464.ABSI01000020_gene354	3.617e-54	195.0	COG5319@1|root,COG5319@2|Bacteria,46VM9@74201|Verrucomicrobia,2IVSB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11228562_2	279714.FuraDRAFT_1896	3.472e-39	154.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria,2KRTR@206351|Neisseriales	206351|Neisseriales	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH3_k127_11228562_0	425104.Ssed_2752	4.103e-147	494.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2NX@1236|Gammaproteobacteria,2Q91E@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH3_k127_11228562_1	880073.Calab_1153	6.35e-76	273.0	COG0591@1|root,COG0591@2|Bacteria,2NRJT@2323|unclassified Bacteria	2|Bacteria	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_11228562_3	867902.Ornrh_0572	1.605e-23	109.0	COG1564@1|root,COG1564@2|Bacteria,4NGJH@976|Bacteroidetes,1I37D@117743|Flavobacteriia	976|Bacteroidetes	H	thiamine pyrophosphokinase	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
YHH3_k127_11252354_1	382464.ABSI01000021_gene369	7.613e-147	491.0	COG1480@1|root,COG1480@2|Bacteria,46S4P@74201|Verrucomicrobia,2ITIA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,HD
YHH3_k127_11252354_5	583355.Caka_1131	7.98e-112	373.0	COG1702@1|root,COG1702@2|Bacteria,46S7S@74201|Verrucomicrobia,3K7UY@414999|Opitutae	414999|Opitutae	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
YHH3_k127_11252354_8	583355.Caka_1130	1.161e-57	204.0	COG0537@1|root,COG0537@2|Bacteria,46T23@74201|Verrucomicrobia,3K81F@414999|Opitutae	414999|Opitutae	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
YHH3_k127_11252354_3	382464.ABSI01000010_gene3762	2.535e-132	429.0	COG0667@1|root,COG0667@2|Bacteria,46U3T@74201|Verrucomicrobia,2ITTY@203494|Verrucomicrobiae	2|Bacteria	C	Aldo/keto reductase family	-	GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_11252354_7	29486.NJ56_11815	3.079e-77	264.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,1RMDJ@1236|Gammaproteobacteria,41DQR@629|Yersinia	1236|Gammaproteobacteria	Q	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate	elbB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009893,GO:0009987,GO:0019216,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045828,GO:0045834,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:0080090,GO:1901576	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
YHH3_k127_11252354_11	583355.Caka_3134	1.569e-23	105.0	COG1934@1|root,COG1934@2|Bacteria,46WSW@74201|Verrucomicrobia,3K8DV@414999|Opitutae	414999|Opitutae	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm	-	-	-	-	-	-	-	-	-	-	-	-	LptC
YHH3_k127_11252354_12	382464.ABSI01000010_gene3767	2.784e-14	81.0	COG1934@1|root,COG1934@2|Bacteria	2|Bacteria	S	lipopolysaccharide binding	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_2
YHH3_k127_11252354_6	583355.Caka_3135	2.457e-99	331.0	COG1137@1|root,COG1137@2|Bacteria,46SDI@74201|Verrucomicrobia,3K77F@414999|Opitutae	414999|Opitutae	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
YHH3_k127_11252354_4	583355.Caka_3136	1.162e-118	389.0	COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia,3K7RB@414999|Opitutae	414999|Opitutae	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
YHH3_k127_11252354_0	382464.ABSI01000010_gene3770	1.323e-149	487.0	COG0593@1|root,COG0593@2|Bacteria,46S6H@74201|Verrucomicrobia,2ITNP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
YHH3_k127_11252354_10	1396141.BATP01000004_gene5855	1.554e-34	137.0	2FBS3@1|root,343WW@2|Bacteria,46X6J@74201|Verrucomicrobia,2IUQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11252354_9	382464.ABSI01000023_gene586	9.876e-52	186.0	COG0346@1|root,COG0346@2|Bacteria,46SUF@74201|Verrucomicrobia,2IUKG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YHH3_k127_11252354_2	1122176.KB903532_gene2470	1.144e-135	447.0	COG3459@1|root,COG3459@2|Bacteria,4PM7T@976|Bacteroidetes,1IVNA@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11257732_2	583355.Caka_1320	1.632e-66	233.0	COG1187@1|root,COG1187@2|Bacteria,46SWQ@74201|Verrucomicrobia,3K72J@414999|Opitutae	414999|Opitutae	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH3_k127_11257732_0	583355.Caka_1322	4.028e-116	380.0	COG0190@1|root,COG0190@2|Bacteria,46TG7@74201|Verrucomicrobia,3K7QM@414999|Opitutae	414999|Opitutae	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
YHH3_k127_11257732_1	583355.Caka_1324	2.56e-92	317.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,46UE8@74201|Verrucomicrobia,3K7D3@414999|Opitutae	414999|Opitutae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
YHH3_k127_11257732_3	1054217.TALC_00208	4.367e-07	57.0	COG0345@1|root,arCOG00455@2157|Archaea,2XTJT@28890|Euryarchaeota,241TZ@183967|Thermoplasmata	183967|Thermoplasmata	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
YHH3_k127_11268223_2	1195246.AGRI_00060	1.661e-57	207.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,463Y3@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
YHH3_k127_11268223_1	497964.CfE428DRAFT_0735	3.373e-62	221.0	COG0637@1|root,COG0637@2|Bacteria,46SWS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	HAD-hyrolase-like	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH3_k127_11268223_0	452637.Oter_3891	8.174e-160	513.0	COG3007@1|root,COG3007@2|Bacteria,46S92@74201|Verrucomicrobia,3K7W2@414999|Opitutae	414999|Opitutae	I	Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP)	fabV	-	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
YHH3_k127_11322922_2	794903.OPIT5_14615	2.339e-54	202.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529,ko:K03435,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
YHH3_k127_11322922_0	583355.Caka_1040	1.392e-123	414.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	Z012_03425	-	3.1.6.14	ko:K01137,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_11322922_1	583355.Caka_3060	1.139e-113	372.0	COG5434@1|root,COG5434@2|Bacteria,46UV6@74201|Verrucomicrobia,3K97E@414999|Opitutae	414999|Opitutae	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
YHH3_k127_11326454_0	56780.SYN_02074	1.4e-273	847.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MQ80@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family	acrB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YHH3_k127_1136769_1	583355.Caka_0913	2.498e-98	328.0	COG0820@1|root,COG0820@2|Bacteria,46UPK@74201|Verrucomicrobia,3K7AA@414999|Opitutae	414999|Opitutae	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
YHH3_k127_1136769_0	583355.Caka_0439	1.545e-118	401.0	COG1757@1|root,COG1757@2|Bacteria	2|Bacteria	C	Na H antiporter	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
YHH3_k127_1136769_3	382464.ABSI01000005_gene1357	4.974e-22	100.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
YHH3_k127_1136769_2	1163407.UU7_11527	1.163e-56	203.0	COG0590@1|root,COG0590@2|Bacteria,1RFCW@1224|Proteobacteria,1S5YA@1236|Gammaproteobacteria,1XC1R@135614|Xanthomonadales	135614|Xanthomonadales	FJ	deaminase	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
YHH3_k127_11405574_3	338966.Ppro_3495	2.045e-34	141.0	COG0705@1|root,COG0705@2|Bacteria,1N258@1224|Proteobacteria,42UB4@68525|delta/epsilon subdivisions,2WQJ3@28221|Deltaproteobacteria,43W1K@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH3_k127_11405574_0	502025.Hoch_5743	1.088e-279	871.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42NJZ@68525|delta/epsilon subdivisions,2WK1Q@28221|Deltaproteobacteria,2YZK2@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
YHH3_k127_11405574_4	502025.Hoch_5742	1.638e-27	115.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,42VFF@68525|delta/epsilon subdivisions,2WR8E@28221|Deltaproteobacteria,2Z2T8@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
YHH3_k127_11405574_2	583355.Caka_1802	1.938e-78	269.0	COG1388@1|root,COG1388@2|Bacteria,46T61@74201|Verrucomicrobia,3K9J0@414999|Opitutae	414999|Opitutae	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LysM
YHH3_k127_11405574_1	452637.Oter_3618	2.566e-133	432.0	COG0556@1|root,COG0556@2|Bacteria,46SF2@74201|Verrucomicrobia,3K76Z@414999|Opitutae	414999|Opitutae	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH3_k127_11427301_1	706587.Desti_3799	2.018e-32	137.0	COG1566@1|root,COG1566@2|Bacteria,1QUDS@1224|Proteobacteria,42QZG@68525|delta/epsilon subdivisions,2WN4C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
YHH3_k127_11427301_2	314345.SPV1_14254	3.21e-25	111.0	COG1977@1|root,COG1977@2|Bacteria,1N4Z0@1224|Proteobacteria	1224|Proteobacteria	H	Molybdopterin converting factor, small subunit	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
YHH3_k127_11427301_0	313628.LNTAR_04471	3.092e-33	132.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530,ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH3_k127_11444782_0	697282.Mettu_2289	2.863e-211	666.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,1XEB1@135618|Methylococcales	135618|Methylococcales	C	reductase 4Fe-4S	-	-	-	-	-	-	-	-	-	-	-	-	NIR_SIR,NIR_SIR_ferr
YHH3_k127_11444782_2	7245.FBpp0256410	4.991e-12	72.0	COG2105@1|root,KOG4450@2759|Eukaryota,3A0XK@33154|Opisthokonta,3BSMM@33208|Metazoa,3D6G4@33213|Bilateria,420FS@6656|Arthropoda,3SNDN@50557|Insecta,453YB@7147|Diptera,45WFF@7214|Drosophilidae	33208|Metazoa	S	Gamma-glutamyl cyclotransferase, AIG2-like	GGACT	GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0016829,GO:0016840,GO:0016842,GO:0042219,GO:0061929,GO:0071704,GO:1901564,GO:1901565,GO:1901575	-	ko:K19761	-	-	-	-	ko00000,ko01000	-	-	-	GGACT
YHH3_k127_11444782_1	382464.ABSI01000010_gene3792	7.88e-38	144.0	COG0334@1|root,COG0334@2|Bacteria,46YXD@74201|Verrucomicrobia,2ITNI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YHH3_k127_11464260_0	655815.ZPR_1012	3.425e-187	604.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_11486229_1	382464.ABSI01000011_gene2551	1.402e-144	467.0	COG1398@1|root,COG1398@2|Bacteria,46SMF@74201|Verrucomicrobia,2IU8N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
YHH3_k127_11486229_2	316057.RPD_0538	6.62e-37	143.0	COG5573@1|root,COG5573@2|Bacteria,1N454@1224|Proteobacteria,2UDGY@28211|Alphaproteobacteria,3K4AV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_11486229_0	382464.ABSI01000005_gene1072	1.981e-160	512.0	COG1609@1|root,COG1609@2|Bacteria,46TVE@74201|Verrucomicrobia,2IVYJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
YHH3_k127_11517914_1	583355.Caka_0857	1.915e-101	340.0	COG0591@1|root,COG0591@2|Bacteria,46ZB9@74201|Verrucomicrobia,3K8WD@414999|Opitutae	414999|Opitutae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_11517914_0	452637.Oter_1765	5.202e-112	365.0	COG1215@1|root,COG1215@2|Bacteria,46SRA@74201|Verrucomicrobia,3K7C7@414999|Opitutae	414999|Opitutae	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_11517914_2	316058.RPB_3231	2.661e-53	211.0	2DM0M@1|root,3175D@2|Bacteria,1MYGG@1224|Proteobacteria,2UA4C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11569161_14	91464.S7335_2919	1.497e-18	95.0	2BFSR@1|root,329MN@2|Bacteria,1G8JT@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
YHH3_k127_11569161_10	583355.Caka_1892	3.109e-40	150.0	COG0361@1|root,COG0361@2|Bacteria,46ZFZ@74201|Verrucomicrobia,3K8AU@414999|Opitutae	414999|Opitutae	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
YHH3_k127_11569161_1	382464.ABSI01000023_gene550	4.608e-133	431.0	COG0031@1|root,COG0031@2|Bacteria,46UMC@74201|Verrucomicrobia,2ITKD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH3_k127_11569161_0	382464.ABSI01000023_gene548	4.121e-163	526.0	COG0415@1|root,COG0415@2|Bacteria,46TVC@74201|Verrucomicrobia,2IU6D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA photolyase	-	-	-	-	-	-	-	-	-	-	-	-	DNA_photolyase,FAD_binding_7
YHH3_k127_11569161_6	378806.STAUR_2315	1.569e-76	269.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria,2YUBK@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
YHH3_k127_11569161_8	382464.ABSI01000010_gene3815	9.987e-48	182.0	COG0697@1|root,COG0697@2|Bacteria,46SMS@74201|Verrucomicrobia,2IVUE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH3_k127_11569161_2	278957.ABEA03000111_gene1365	1.026e-109	387.0	COG0616@1|root,COG0616@2|Bacteria,46SQ5@74201|Verrucomicrobia,3K7C3@414999|Opitutae	414999|Opitutae	OU	TIGRFAM signal peptide peptidase SppA, 67K type	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
YHH3_k127_11569161_7	583355.Caka_0669	1.108e-54	198.0	COG2151@1|root,COG2151@2|Bacteria,46VFI@74201|Verrucomicrobia,3K7XT@414999|Opitutae	414999|Opitutae	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
YHH3_k127_11569161_4	452637.Oter_3550	2.157e-85	294.0	COG4974@1|root,COG4974@2|Bacteria,46U04@74201|Verrucomicrobia,3K7J0@414999|Opitutae	414999|Opitutae	D	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH3_k127_11569161_5	794903.OPIT5_10930	1.092e-84	293.0	COG0715@1|root,COG0715@2|Bacteria,46X2C@74201|Verrucomicrobia,3K9J8@414999|Opitutae	414999|Opitutae	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
YHH3_k127_11569161_9	583355.Caka_2266	3.349e-43	176.0	COG0457@1|root,COG0457@2|Bacteria	583355.Caka_2266|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11569161_13	583355.Caka_2267	3.808e-29	124.0	COG0810@1|root,COG0810@2|Bacteria,46WRI@74201|Verrucomicrobia,3K8HB@414999|Opitutae	414999|Opitutae	M	Biopolymer transporter TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH3_k127_11569161_12	382464.ABSI01000005_gene1358	2.859e-35	141.0	COG0848@1|root,COG0848@2|Bacteria,46XKT@74201|Verrucomicrobia,2IW5H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
YHH3_k127_11569161_11	583355.Caka_2269	3.157e-37	148.0	COG0811@1|root,COG0811@2|Bacteria,46VPT@74201|Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH3_k127_11569161_3	382464.ABSI01000007_gene4063	1.358e-89	312.0	COG0811@1|root,COG0811@2|Bacteria,46UAW@74201|Verrucomicrobia,2IVTF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
YHH3_k127_11569161_15	583355.Caka_2271	1.399e-14	79.0	2E0WS@1|root,32WDT@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
YHH3_k127_1161861_0	452637.Oter_3493	1.537e-68	250.0	COG4206@1|root,COG4206@2|Bacteria,46U34@74201|Verrucomicrobia,3K7RP@414999|Opitutae	414999|Opitutae	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
YHH3_k127_1161861_1	926569.ANT_10750	1.072e-41	160.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yigM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
YHH3_k127_11621488_0	278957.ABEA03000196_gene407	6.497e-139	451.0	COG0407@1|root,COG0407@2|Bacteria,46WW7@74201|Verrucomicrobia,3K8TQ@414999|Opitutae	414999|Opitutae	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH3_k127_11621488_1	665956.HMPREF1032_00853	9.911e-116	386.0	COG0407@1|root,COG0407@2|Bacteria,1V4YU@1239|Firmicutes,24KSS@186801|Clostridia,3WPW7@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
YHH3_k127_11621488_2	314230.DSM3645_25081	1.125e-38	154.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,2J0IT@203682|Planctomycetes	203682|Planctomycetes	K	COG2207 AraC-type DNA-binding domain-containing	-	-	-	ko:K02855	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18
YHH3_k127_11651664_0	452637.Oter_4009	2.51e-157	505.0	COG0156@1|root,COG0156@2|Bacteria,46TFY@74201|Verrucomicrobia,3K7SB@414999|Opitutae	414999|Opitutae	H	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH3_k127_11651664_2	497965.Cyan7822_3359	3.33e-37	156.0	COG0438@1|root,COG0438@2|Bacteria,1GCS0@1117|Cyanobacteria	1117|Cyanobacteria	H	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
YHH3_k127_11651664_1	452637.Oter_4006	8.91e-69	252.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,Methyltransf_24
YHH3_k127_11744017_0	583355.Caka_0712	2.299e-130	431.0	COG0617@1|root,COG0617@2|Bacteria,46UER@74201|Verrucomicrobia,3K732@414999|Opitutae	414999|Opitutae	J	Polynucleotide adenylyltransferase	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
YHH3_k127_11744017_1	592029.DDD_1877	5.813e-08	64.0	COG1572@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	4.2.2.1,4.2.2.3	ko:K01727,ko:K01729,ko:K14274,ko:K20276,ko:K20951,ko:K20952	ko00040,ko00051,ko02024,ko05111,map00040,map00051,map02024,map05111	-	R02427,R03706	RC00713	ko00000,ko00001,ko01000	-	PL8	-	CHU_C,Laminin_G_3,PKD,SGL
YHH3_k127_11752132_0	1379698.RBG1_1C00001G0608	1.144e-82	310.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
YHH3_k127_11752132_5	883078.HMPREF9695_03091	7.638e-08	64.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	CP_1072	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
YHH3_k127_11752132_4	1430331.EP10_06355	1.358e-14	86.0	COG4886@1|root,COG4886@2|Bacteria,1V3UH@1239|Firmicutes,4HM8K@91061|Bacilli	91061|Bacilli	E	Leucine-rich repeat (LRR) protein	inlA	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030260,GO:0030312,GO:0035635,GO:0044403,GO:0044409,GO:0044419,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	-	ko:K13730,ko:K13731	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Flg_new,Gram_pos_anchor,Internalin_N,LRR_4,LRR_6,LRR_adjacent,NEAT,SLH,Strep_his_triad,fn3
YHH3_k127_11752132_1	1089551.KE386572_gene860	1.662e-51	192.0	COG1082@1|root,COG1082@2|Bacteria,1NRDM@1224|Proteobacteria,2UNWH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_11752132_3	391587.KAOT1_16893	1.744e-44	175.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,4NFEW@976|Bacteroidetes,1HZIS@117743|Flavobacteriia	976|Bacteroidetes	E	Dehydrogenase	-	-	-	ko:K02030,ko:K03810	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	ADH_zinc_N,GFO_IDH_MocA
YHH3_k127_11752132_2	1499967.BAYZ01000118_gene3277	2.742e-51	189.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
YHH3_k127_11799245_0	143224.JQMD01000002_gene3616	1.189e-179	574.0	COG5434@1|root,COG5434@2|Bacteria,4NDWX@976|Bacteroidetes,1HZRR@117743|Flavobacteriia	976|Bacteroidetes	M	Parallel beta-helix repeats	glaB	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YHH3_k127_11799245_1	1123277.KB893206_gene3363	1.499e-148	487.0	COG3119@1|root,COG3119@2|Bacteria,4NGCH@976|Bacteroidetes,47MFY@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_11799245_2	1396141.BATP01000003_gene4863	7.35e-27	115.0	COG1649@1|root,COG1649@2|Bacteria,46UNR@74201|Verrucomicrobia,2IWQG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
YHH3_k127_11810121_0	649638.Trad_1843	2.012e-92	317.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,PmoA
YHH3_k127_11810121_1	583355.Caka_0660	7.712e-24	106.0	COG0782@1|root,COG0782@2|Bacteria,46T65@74201|Verrucomicrobia,3K8BG@414999|Opitutae	414999|Opitutae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11810121_2	1266909.AUAG01000003_gene913	1.48e-19	91.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
YHH3_k127_11810121_3	105559.Nwat_0071	6.844e-13	68.0	COG1724@1|root,COG1724@2|Bacteria,1N7S3@1224|Proteobacteria,1SE2D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	PFAM YcfA family protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH3_k127_11823078_1	411154.GFO_1948	6.379e-36	139.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,1HYXD@117743|Flavobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
YHH3_k127_11823078_0	551789.ATVJ01000003_gene311	2.428e-72	257.0	2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,2TTDU@28211|Alphaproteobacteria,43WQ2@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
YHH3_k127_11823078_3	1191523.MROS_1693	2.84e-06	54.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM60,CBM_4_9,CBM_6,Cellulase,F5_F8_type_C
YHH3_k127_11823078_2	452637.Oter_2353	7.684e-14	73.0	COG0285@1|root,COG0285@2|Bacteria,46UIC@74201|Verrucomicrobia,3K7F0@414999|Opitutae	414999|Opitutae	H	Belongs to the folylpolyglutamate synthase family	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
YHH3_k127_11825929_0	471854.Dfer_5616	6.43e-82	285.0	COG1735@1|root,COG1735@2|Bacteria,4NJYF@976|Bacteroidetes,47NZQ@768503|Cytophagia	976|Bacteroidetes	S	Phosphotriesterase family	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
YHH3_k127_11825929_3	1304888.ATWF01000001_gene1791	1.587e-15	78.0	COG5450@1|root,COG5450@2|Bacteria,2GGN7@200930|Deferribacteres	200930|Deferribacteres	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
YHH3_k127_11825929_1	163908.KB235896_gene1469	2.127e-30	127.0	COG1487@1|root,COG1487@2|Bacteria,1G736@1117|Cyanobacteria,1HSR1@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_11825929_4	1235803.C825_01175	2.901e-11	77.0	COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,2G3HE@200643|Bacteroidia,22Z10@171551|Porphyromonadaceae	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
YHH3_k127_11825929_2	886293.Sinac_5707	1.694e-17	93.0	COG3712@1|root,COG3712@2|Bacteria,2IZ99@203682|Planctomycetes	203682|Planctomycetes	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
YHH3_k127_11916771_0	1123392.AQWL01000007_gene971	2.327e-46	181.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,1KRQS@119069|Hydrogenophilales	119069|Hydrogenophilales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS
YHH3_k127_11916771_1	314278.NB231_16683	9.189e-45	170.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1WXDV@135613|Chromatiales	135613|Chromatiales	K	response regulator receiver	-	-	-	ko:K13041	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
YHH3_k127_11916771_2	994573.T472_0215450	2.914e-13	76.0	29DE2@1|root,300BX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11917259_7	794903.OPIT5_03560	3.695e-42	164.0	COG0771@1|root,COG0771@2|Bacteria,46UT1@74201|Verrucomicrobia,3K78H@414999|Opitutae	414999|Opitutae	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH3_k127_11917259_1	583355.Caka_3068	1.887e-147	475.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia,3K7EK@414999|Opitutae	414999|Opitutae	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
YHH3_k127_11917259_4	452637.Oter_2630	1.202e-95	330.0	COG0770@1|root,COG0770@2|Bacteria,46UDV@74201|Verrucomicrobia,3K7ND@414999|Opitutae	414999|Opitutae	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	-	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH3_k127_11917259_2	583355.Caka_3066	3.208e-136	452.0	COG0769@1|root,COG0769@2|Bacteria,46SGG@74201|Verrucomicrobia,3K7EA@414999|Opitutae	414999|Opitutae	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH3_k127_11917259_0	583355.Caka_3065	3.032e-167	543.0	COG0768@1|root,COG0768@2|Bacteria,46SEZ@74201|Verrucomicrobia,3K799@414999|Opitutae	414999|Opitutae	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
YHH3_k127_11917259_3	583355.Caka_3062	1.034e-99	335.0	COG0275@1|root,COG0275@2|Bacteria,46UYN@74201|Verrucomicrobia,3K74T@414999|Opitutae	414999|Opitutae	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
YHH3_k127_11917259_10	382464.ABSI01000002_gene4350	2.104e-22	102.0	COG2001@1|root,COG2001@2|Bacteria,46T5G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
YHH3_k127_11917259_5	583355.Caka_0710	6.847e-83	282.0	COG1189@1|root,COG1189@2|Bacteria,46SM8@74201|Verrucomicrobia,3K7BI@414999|Opitutae	414999|Opitutae	J	S4 RNA-binding domain	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
YHH3_k127_11917259_6	583355.Caka_0711	6.265e-66	235.0	COG0061@1|root,COG0061@2|Bacteria,46SUQ@74201|Verrucomicrobia,3K7CE@414999|Opitutae	414999|Opitutae	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
YHH3_k127_11917259_8	278957.ABEA03000118_gene1142	4.646e-28	122.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,3K80X@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
YHH3_k127_11940601_1	1307761.L21SP2_0496	1.678e-15	83.0	COG0546@1|root,COG0546@2|Bacteria,2J5KH@203691|Spirochaetes	203691|Spirochaetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH3_k127_11940601_0	1122925.KB895379_gene2322	5.846e-73	266.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26RMX@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
YHH3_k127_11973341_1	859657.RPSI07_3221	2.238e-44	180.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2VM13@28216|Betaproteobacteria,1KH59@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
YHH3_k127_11973341_2	1336235.JAEG01000022_gene554	6.658e-30	121.0	COG2963@1|root,COG2963@2|Bacteria,1NXMF@1224|Proteobacteria,2USYW@28211|Alphaproteobacteria,4BFXT@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
YHH3_k127_11973341_0	1121943.KB900012_gene4060	2.588e-120	394.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RR8F@1236|Gammaproteobacteria,1XRIQ@135619|Oceanospirillales	135619|Oceanospirillales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve_3
YHH3_k127_11973341_3	1158165.KB898876_gene1410	1.057e-16	83.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1WZXR@135613|Chromatiales	135613|Chromatiales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12049997_0	583355.Caka_1119	3.434e-169	557.0	COG0025@1|root,COG0569@1|root,COG1762@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	iJN678.sll0556	Na_H_Exchanger,PTS_EIIA_2,TrkA_N
YHH3_k127_12049997_4	1408473.JHXO01000011_gene3002	2.09e-49	185.0	COG0546@1|root,COG0546@2|Bacteria,4NRB4@976|Bacteroidetes,2FTCK@200643|Bacteroidia	976|Bacteroidetes	S	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH3_k127_12049997_2	583355.Caka_2856	2.423e-108	357.0	COG0528@1|root,COG0528@2|Bacteria,46S4W@74201|Verrucomicrobia,3K7UI@414999|Opitutae	414999|Opitutae	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YHH3_k127_12049997_3	382464.ABSI01000011_gene2535	2.008e-55	199.0	COG0233@1|root,COG0233@2|Bacteria,46V49@74201|Verrucomicrobia,2IUA0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
YHH3_k127_12049997_1	452637.Oter_4153	2.659e-109	364.0	COG0263@1|root,COG0263@2|Bacteria,46SWM@74201|Verrucomicrobia,3K78E@414999|Opitutae	414999|Opitutae	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
YHH3_k127_1205290_0	1191523.MROS_0617	2.755e-103	347.0	COG1313@1|root,COG1313@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
YHH3_k127_1205290_1	335543.Sfum_0211	6.765e-79	270.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2X5K8@28221|Deltaproteobacteria,2MQGN@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
YHH3_k127_12062421_0	903818.KI912269_gene149	4.925e-58	229.0	COG4932@1|root,COG4932@2|Bacteria,3Y8E2@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YHH3_k127_12074588_0	1122197.ATWI01000012_gene588	1.475e-132	430.0	COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,1RMWR@1236|Gammaproteobacteria,465AU@72275|Alteromonadaceae	1236|Gammaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase	ldhA	GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006067,GO:0006082,GO:0006083,GO:0006089,GO:0006090,GO:0006091,GO:0006103,GO:0006105,GO:0006113,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008720,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015942,GO:0015980,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019318,GO:0019362,GO:0019637,GO:0019660,GO:0019664,GO:0019666,GO:0019693,GO:0019752,GO:0032787,GO:0034308,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0050896,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0070404,GO:0071704,GO:0072521,GO:0072524,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901615	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	iJN746.PP_1649,iPC815.YPO2329,iSFV_1184.SFV_1805,iSF_1195.SF1814,iSFxv_1172.SFxv_2031,iS_1188.S1459	2-Hacid_dh,2-Hacid_dh_C
YHH3_k127_12074588_3	452637.Oter_3639	2.339e-08	65.0	28Q9D@1|root,2ZCS4@2|Bacteria,46WV1@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12074588_2	754331.AEME01000001_gene108	1.637e-16	82.0	2E9BS@1|root,333JI@2|Bacteria,1N09N@1224|Proteobacteria,1SA8V@1236|Gammaproteobacteria,3XQ13@561|Escherichia	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2492)	yecH	-	-	-	-	-	-	-	-	-	-	-	DUF2492
YHH3_k127_12074588_1	1121939.L861_22675	1.959e-48	180.0	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,1RMJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YHH3_k127_12077764_2	583355.Caka_1811	3.476e-79	272.0	COG1387@1|root,COG1387@2|Bacteria,46U67@74201|Verrucomicrobia,3K8DP@414999|Opitutae	414999|Opitutae	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
YHH3_k127_12077764_0	382464.ABSI01000020_gene232	4.813e-180	578.0	COG4166@1|root,COG4166@2|Bacteria,46TR7@74201|Verrucomicrobia,2IWMV@203494|Verrucomicrobiae	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iECABU_c1320.ECABU_c15240,iECNA114_1301.ECNA114_1414,iECSF_1327.ECSF_1224,iNRG857_1313.NRG857_06385,iUMNK88_1353.UMNK88_1667	SBP_bac_5
YHH3_k127_12077764_1	452637.Oter_2420	1.751e-116	382.0	COG0601@1|root,COG0601@2|Bacteria,46SJN@74201|Verrucomicrobia,3K7V9@414999|Opitutae	414999|Opitutae	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
YHH3_k127_12077764_3	452637.Oter_2419	2.388e-75	259.0	COG1173@1|root,COG1173@2|Bacteria,46SN0@74201|Verrucomicrobia,3K744@414999|Opitutae	414999|Opitutae	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
YHH3_k127_12083073_2	583355.Caka_2105	1.265e-105	350.0	COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia,3K7XV@414999|Opitutae	414999|Opitutae	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
YHH3_k127_12083073_5	794903.OPIT5_11695	7.735e-24	104.0	2BFTV@1|root,329NU@2|Bacteria,46Z0C@74201|Verrucomicrobia,3K8FB@414999|Opitutae	414999|Opitutae	S	PFAM H transporting two-sector ATPase C subunit	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
YHH3_k127_12083073_4	583355.Caka_2107	1.367e-40	156.0	COG0711@1|root,COG0711@2|Bacteria,46SYI@74201|Verrucomicrobia,3K89M@414999|Opitutae	414999|Opitutae	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
YHH3_k127_12083073_6	278957.ABEA03000091_gene707	1.733e-08	61.0	COG0712@1|root,COG0712@2|Bacteria,46TC4@74201|Verrucomicrobia,3K886@414999|Opitutae	414999|Opitutae	C	ATP synthase delta (OSCP) subunit	-	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
YHH3_k127_12083073_0	382464.ABSI01000012_gene2278	5.031e-240	751.0	COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia,2ITR0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
YHH3_k127_12083073_3	794903.OPIT5_11715	3.122e-88	299.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia,3K742@414999|Opitutae	414999|Opitutae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
YHH3_k127_12083073_1	382464.ABSI01000012_gene2280	2.851e-121	393.0	COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia,2IU0R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH3_k127_12108897_6	518766.Rmar_0276	3.688e-39	151.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1FJ6W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Eukaryotic integral membrane protein (DUF1751)	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
YHH3_k127_12108897_4	583355.Caka_1959	3.132e-57	203.0	COG1225@1|root,COG1225@2|Bacteria,46V63@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YHH3_k127_12108897_0	497964.CfE428DRAFT_1607	0.0	1201.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YHH3_k127_12108897_5	278957.ABEA03000061_gene3160	9.136e-48	177.0	COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,3K84E@414999|Opitutae	414999|Opitutae	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12108897_2	452637.Oter_2687	1.659e-157	510.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,46SWK@74201|Verrucomicrobia,3K87J@414999|Opitutae	414999|Opitutae	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,PAS_3,SpoIIE
YHH3_k127_12108897_1	382464.ABSI01000021_gene413	9.637e-193	609.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH3_k127_12108897_3	278957.ABEA03000097_gene790	4.179e-72	253.0	COG1561@1|root,COG1561@2|Bacteria,46V58@74201|Verrucomicrobia,3K7K3@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
YHH3_k127_12120685_1	886293.Sinac_5707	1.576e-16	95.0	COG3712@1|root,COG3712@2|Bacteria,2IZ99@203682|Planctomycetes	203682|Planctomycetes	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
YHH3_k127_12120685_2	1463820.JOGW01000005_gene3331	2.954e-11	78.0	2DGAD@1|root,2ZV4Y@2|Bacteria,2IF7H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12120685_0	620914.JH621258_gene1025	1.63e-52	202.0	COG1874@1|root,COG1874@2|Bacteria,4PNM8@976|Bacteroidetes,1I86X@117743|Flavobacteriia,2YKXH@290174|Aquimarina	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12120954_1	448385.sce6671	2.445e-25	114.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.5.1.28	ko:K01447,ko:K07126,ko:K13582	ko04112,map04112	-	R04112	RC00064,RC00141	ko00000,ko00001,ko01000	-	-	-	LysM,PG_binding_1,Sel1
YHH3_k127_12120954_2	1242864.D187_004801	1.808e-06	58.0	2A461@1|root,30SR2@2|Bacteria,1PC3D@1224|Proteobacteria,433A7@68525|delta/epsilon subdivisions,2WXTE@28221|Deltaproteobacteria,2YW5Q@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12137841_1	566466.NOR53_904	9.602e-97	333.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RR2N@1236|Gammaproteobacteria,1J8R6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,DUF1800
YHH3_k127_12137841_0	313606.M23134_07053	7.578e-114	382.0	COG4102@1|root,COG4102@2|Bacteria,4NJKZ@976|Bacteroidetes,47TV4@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH3_k127_12175117_6	452637.Oter_3658	7.448e-10	61.0	COG5012@1|root,COG5012@2|Bacteria,46V56@74201|Verrucomicrobia,3K7ZT@414999|Opitutae	414999|Opitutae	S	Methionine synthase B12-binding module cap domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
YHH3_k127_12175117_5	426117.M446_2538	6.788e-11	66.0	COG2963@1|root,COG2963@2|Bacteria,1NBUS@1224|Proteobacteria,2UHXZ@28211|Alphaproteobacteria,1JVB9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
YHH3_k127_12175117_2	485913.Krac_5551	1.896e-60	220.0	COG2801@1|root,COG2801@2|Bacteria,2G8GQ@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
YHH3_k127_12175117_0	794903.OPIT5_11785	9.452e-96	319.0	COG0708@1|root,COG0708@2|Bacteria,46TGT@74201|Verrucomicrobia,3K7VW@414999|Opitutae	414999|Opitutae	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
YHH3_k127_12175117_3	240016.ABIZ01000001_gene876	1.131e-52	198.0	COG2940@1|root,COG2940@2|Bacteria,46W0B@74201|Verrucomicrobia,2IUGA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
YHH3_k127_12175117_4	794903.OPIT5_19970	9.878e-24	112.0	COG5010@1|root,COG5010@2|Bacteria,46Z5S@74201|Verrucomicrobia,3K888@414999|Opitutae	414999|Opitutae	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12175117_1	452637.Oter_2030	4.549e-92	306.0	COG0825@1|root,COG0825@2|Bacteria,46SE1@74201|Verrucomicrobia,3K7TK@414999|Opitutae	414999|Opitutae	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
YHH3_k127_12181684_0	760568.Desku_2308	4.423e-128	421.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,260R6@186807|Peptococcaceae	186801|Clostridia	C	NADH dehydrogenase	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
YHH3_k127_12181684_1	573413.Spirs_0476	7.804e-56	200.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YHH3_k127_12181684_2	382464.ABSI01000010_gene3491	1.14e-54	196.0	COG4447@1|root,COG4447@2|Bacteria,46VN1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12204032_3	794903.OPIT5_27645	0.0003606	51.0	COG3064@1|root,COG3064@2|Bacteria,46VF9@74201|Verrucomicrobia,3K7ZJ@414999|Opitutae	414999|Opitutae	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12204032_0	234267.Acid_2265	1.388e-170	552.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH3_k127_12204032_1	234267.Acid_2264	4.37e-170	551.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
YHH3_k127_12204032_2	313606.M23134_01323	3.684e-27	115.0	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,47QT5@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_12206074_2	583355.Caka_2083	4.275e-29	121.0	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia,3K7J5@414999|Opitutae	414999|Opitutae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
YHH3_k127_12206074_0	382464.ABSI01000010_gene3345	8.679e-118	390.0	COG4977@1|root,COG4977@2|Bacteria,46VJD@74201|Verrucomicrobia,2IWPJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Peripla_BP_3
YHH3_k127_12206074_1	382464.ABSI01000010_gene3344	1.834e-46	173.0	COG0153@1|root,COG0153@2|Bacteria,46V7W@74201|Verrucomicrobia,2IU6C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Galactokinase galactose-binding signature	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
YHH3_k127_12217096_2	1379701.JPJC01000194_gene767	2.467e-28	116.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2TSBE@28211|Alphaproteobacteria,2K04P@204457|Sphingomonadales	204457|Sphingomonadales	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
YHH3_k127_12217096_1	583355.Caka_1613	4.658e-67	233.0	COG0634@1|root,COG0634@2|Bacteria,46T02@74201|Verrucomicrobia,3K7XB@414999|Opitutae	414999|Opitutae	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
YHH3_k127_12217096_0	382464.ABSI01000011_gene2491	2.947e-94	320.0	COG0673@1|root,COG0673@2|Bacteria,46TQ2@74201|Verrucomicrobia,2IVP0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_12217096_3	1499967.BAYZ01000082_gene1019	7.918e-25	104.0	COG1943@1|root,COG1943@2|Bacteria,2NRUU@2323|unclassified Bacteria	2|Bacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH3_k127_12276716_2	583355.Caka_1605	2.558e-44	171.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,3K75U@414999|Opitutae	414999|Opitutae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
YHH3_k127_12276716_5	452637.Oter_2586	1.305e-18	94.0	2E533@1|root,32ZW9@2|Bacteria,46SZX@74201|Verrucomicrobia,3K856@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12276716_1	452637.Oter_2777	5.636e-76	259.0	COG0353@1|root,COG0353@2|Bacteria,46SU3@74201|Verrucomicrobia,3K72H@414999|Opitutae	414999|Opitutae	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim,Toprim_4
YHH3_k127_12276716_4	583355.Caka_0266	3.258e-25	108.0	COG0718@1|root,COG0718@2|Bacteria,46TA9@74201|Verrucomicrobia,3K88P@414999|Opitutae	414999|Opitutae	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
YHH3_k127_12276716_0	316058.RPB_1734	1.824e-91	315.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,3JRHP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	amidohydrolase	MA20_15970	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YHH3_k127_12276716_3	278957.ABEA03000017_gene2960	3.687e-33	135.0	COG2197@1|root,COG2197@2|Bacteria,46XU7@74201|Verrucomicrobia,3K85E@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_12302849_2	29073.XP_008707814.1	1.382e-06	56.0	COG5272@1|root,KOG0010@2759|Eukaryota,39V3V@33154|Opisthokonta,3BIVH@33208|Metazoa,3D102@33213|Bilateria,48AUD@7711|Chordata,492BW@7742|Vertebrata,3JFYH@40674|Mammalia,3EJPS@33554|Carnivora	33208|Metazoa	O	Ubiquitin homologues	UBQLN3	-	-	ko:K22254	-	-	-	-	ko00000,ko03051	-	-	-	UBA,ubiquitin
YHH3_k127_12302849_0	583355.Caka_0927	7.461e-165	526.0	COG2812@1|root,COG2812@2|Bacteria,46SGC@74201|Verrucomicrobia,3K7MI@414999|Opitutae	414999|Opitutae	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
YHH3_k127_12302849_1	93220.LV28_22660	2.695e-13	73.0	COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,2VRVD@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Glycine cleavage system regulatory protein	gcvR	-	-	-	-	-	-	-	-	-	-	-	ACT,ACT_6
YHH3_k127_12304989_0	382464.ABSI01000010_gene3353	1.08e-134	472.0	COG1629@1|root,COG1629@2|Bacteria	382464.ABSI01000010_gene3353|-	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12304989_1	502025.Hoch_2977	1.464e-06	51.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
YHH3_k127_12323837_0	583355.Caka_0705	8.963e-71	246.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_12332713_1	743722.Sph21_2303	2.537e-128	417.0	COG3250@1|root,COG3250@2|Bacteria,4PN2B@976|Bacteroidetes,1IQ6X@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolases family 2, sugar binding domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2,Glyco_hydro_2_N
YHH3_k127_12332713_0	742727.HMPREF9447_02682	7.734e-229	741.0	COG3250@1|root,COG3250@2|Bacteria,4NHBP@976|Bacteroidetes,2FN8A@200643|Bacteroidia,4APFJ@815|Bacteroidaceae	976|Bacteroidetes	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_12387081_2	335543.Sfum_1331	2.006e-26	122.0	2CK1R@1|root,32V4M@2|Bacteria,1NNEB@1224|Proteobacteria,437YS@68525|delta/epsilon subdivisions,2X38Q@28221|Deltaproteobacteria,2MSEY@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12387081_0	886293.Sinac_5850	2.13e-86	298.0	COG2006@1|root,COG2006@2|Bacteria,2J0IK@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YHH3_k127_12387081_1	502025.Hoch_0561	4.042e-31	133.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2YW51@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
YHH3_k127_12404791_0	452637.Oter_1904	3.782e-171	549.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,3K7NF@414999|Opitutae	74201|Verrucomicrobia	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH3_k127_12411033_4	1121004.ATVC01000027_gene146	6.154e-08	56.0	COG1280@1|root,COG1280@2|Bacteria,1RD4I@1224|Proteobacteria,2VQ25@28216|Betaproteobacteria,2KR7M@206351|Neisseriales	206351|Neisseriales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
YHH3_k127_12411033_1	558884.JRGM01000138_gene827	3.397e-70	246.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,1S0A5@1236|Gammaproteobacteria,1Y45P@135624|Aeromonadales	135624|Aeromonadales	GK	ROK family	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YHH3_k127_12411033_3	583355.Caka_2957	2.039e-62	218.0	COG0295@1|root,COG0295@2|Bacteria	2|Bacteria	F	cytidine deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP2
YHH3_k127_12411033_0	344747.PM8797T_05430	1.326e-124	410.0	COG2170@1|root,COG2170@2|Bacteria,2IXAU@203682|Planctomycetes	203682|Planctomycetes	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
YHH3_k127_12411033_2	575540.Isop_0122	1.919e-67	237.0	COG1473@1|root,COG1473@2|Bacteria,2IY78@203682|Planctomycetes	203682|Planctomycetes	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YHH3_k127_12442029_2	583355.Caka_0731	3.697e-65	227.0	COG0703@1|root,COG0703@2|Bacteria,46YZV@74201|Verrucomicrobia,3K80S@414999|Opitutae	414999|Opitutae	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
YHH3_k127_12442029_4	452637.Oter_3874	2.359e-56	201.0	COG1259@1|root,COG1259@2|Bacteria,46SW6@74201|Verrucomicrobia,3K81A@414999|Opitutae	414999|Opitutae	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
YHH3_k127_12442029_1	583355.Caka_0733	1.69e-130	424.0	COG0042@1|root,COG0042@2|Bacteria,46TSS@74201|Verrucomicrobia,3K73J@414999|Opitutae	414999|Opitutae	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
YHH3_k127_12442029_3	382464.ABSI01000013_gene1705	1.209e-62	222.0	COG0325@1|root,COG0325@2|Bacteria,46SV2@74201|Verrucomicrobia,2IU7Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
YHH3_k127_12442029_0	452637.Oter_0497	1.765e-136	441.0	COG0583@1|root,COG0583@2|Bacteria,46SCJ@74201|Verrucomicrobia,3K7FY@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YHH3_k127_12465933_1	497964.CfE428DRAFT_2840	3.376e-156	510.0	COG3519@1|root,COG3519@2|Bacteria,46TGI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Type VI secretion system, TssF	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_TssF
YHH3_k127_12465933_4	497964.CfE428DRAFT_2839	1.991e-43	164.0	COG3518@1|root,COG3518@2|Bacteria,46WW6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Gene 25-like lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	GPW_gp25
YHH3_k127_12465933_2	497964.CfE428DRAFT_2838	6.609e-73	254.0	COG4455@1|root,COG4455@2|Bacteria,46VF7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ImpE protein	-	-	-	-	-	-	-	-	-	-	-	-	ImpE
YHH3_k127_12465933_3	1121035.AUCH01000005_gene78	9.342e-51	184.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,2WEFR@28216|Betaproteobacteria,2M03R@206389|Rhodocyclales	206389|Rhodocyclales	S	This family consists of several bacterial proteins of	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
YHH3_k127_12465933_0	765913.ThidrDRAFT_2282	2.771e-237	741.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,1WXN1@135613|Chromatiales	135613|Chromatiales	S	Type VI secretion protein, EvpB/VC_A0108, tail sheath	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
YHH3_k127_12465933_5	1192124.LIG30_0577	8.671e-43	158.0	COG3516@1|root,COG3516@2|Bacteria,1RAZQ@1224|Proteobacteria,2VQ4P@28216|Betaproteobacteria,1K60I@119060|Burkholderiaceae	28216|Betaproteobacteria	S	TIGRFAM type VI secretion protein, VC_A0107 family	-	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
YHH3_k127_12469413_1	1410676.JNKL01000007_gene186	1.451e-41	153.0	COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,1RMU4@1236|Gammaproteobacteria,1Y3DV@135624|Aeromonadales	135624|Aeromonadales	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YHH3_k127_12469413_2	583355.Caka_2531	2.977e-25	107.0	COG0695@1|root,COG0695@2|Bacteria,46TC3@74201|Verrucomicrobia,3K8HC@414999|Opitutae	414999|Opitutae	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
YHH3_k127_12469413_0	644282.Deba_2729	1.852e-276	877.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH3_k127_1248374_2	583355.Caka_0797	1.237e-19	91.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	gcdC	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
YHH3_k127_1248374_0	1238182.C882_2535	9.293e-156	500.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,2U1JW@28211|Alphaproteobacteria,2JR84@204441|Rhodospirillales	204441|Rhodospirillales	C	Na+-transporting oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
YHH3_k127_1248374_1	316067.Geob_0392	6.266e-148	481.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YHH3_k127_12494139_0	1453505.JASY01000001_gene3245	1.326e-142	468.0	COG2755@1|root,COG3866@1|root,COG4677@1|root,COG2755@2|Bacteria,COG3866@2|Bacteria,COG4677@2|Bacteria,4NEEI@976|Bacteroidetes,1IK65@117743|Flavobacteriia	2|Bacteria	G	PFAM Pectinesterase	pemA	GO:0005575,GO:0005576	3.1.1.11	ko:K01051,ko:K10297	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000,ko04121	-	-	-	Beta_helix,Pectinesterase
YHH3_k127_12494139_1	313596.RB2501_03175	2.146e-11	64.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1HWN8@117743|Flavobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
YHH3_k127_12506117_3	522373.Smlt0634	8.752e-87	300.0	COG0382@1|root,COG0560@1|root,COG0382@2|Bacteria,COG0560@2|Bacteria,1MXCM@1224|Proteobacteria,1RRWB@1236|Gammaproteobacteria,1X353@135614|Xanthomonadales	135614|Xanthomonadales	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
YHH3_k127_12506117_2	1382306.JNIM01000001_gene3764	7.513e-115	385.0	COG0277@1|root,COG0277@2|Bacteria,2G8B5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
YHH3_k127_12506117_0	583355.Caka_0410	3.073e-162	523.0	COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia,3K7JM@414999|Opitutae	414999|Opitutae	M	Mur ligase	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH3_k127_12506117_4	794903.OPIT5_22950	1.289e-86	295.0	COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia,3K768@414999|Opitutae	414999|Opitutae	L	UreE urease accessory protein, C-terminal domain	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH3_k127_12506117_1	382464.ABSI01000010_gene3270	1.021e-121	398.0	COG0334@1|root,COG0334@2|Bacteria,46S9K@74201|Verrucomicrobia,2ITH4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YHH3_k127_12568637_3	278957.ABEA03000180_gene2017	8.632e-34	132.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,3K8AV@414999|Opitutae	414999|Opitutae	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YHH3_k127_12568637_0	382464.ABSI01000006_gene754	2.772e-283	877.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,2ITQ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YHH3_k127_12568637_1	794903.OPIT5_06540	3.649e-93	309.0	COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia,3K7DM@414999|Opitutae	414999|Opitutae	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
YHH3_k127_12568637_2	452637.Oter_4585	2.952e-64	224.0	COG0590@1|root,COG0590@2|Bacteria,46SZZ@74201|Verrucomicrobia,3K7ZA@414999|Opitutae	414999|Opitutae	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
YHH3_k127_12596700_6	156889.Mmc1_2290	6.349e-08	57.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2U9IE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
YHH3_k127_12596700_3	56107.Cylst_5225	1.509e-37	158.0	29WGE@1|root,30I2I@2|Bacteria,1GFWI@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12596700_2	583355.Caka_1444	8.518e-41	162.0	COG2374@1|root,COG2374@2|Bacteria,46VEK@74201|Verrucomicrobia,3K81M@414999|Opitutae	414999|Opitutae	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YHH3_k127_12596700_1	583355.Caka_1445	1.395e-155	501.0	COG0501@1|root,COG0501@2|Bacteria,46TVV@74201|Verrucomicrobia,3K72R@414999|Opitutae	414999|Opitutae	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
YHH3_k127_12596700_5	583355.Caka_1051	1.48e-16	83.0	COG1722@1|root,COG1722@2|Bacteria,46TB2@74201|Verrucomicrobia,3K8ES@414999|Opitutae	414999|Opitutae	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
YHH3_k127_12596700_0	452637.Oter_2780	1.625e-262	822.0	COG1154@1|root,COG1154@2|Bacteria,46SAU@74201|Verrucomicrobia,3K7CY@414999|Opitutae	414999|Opitutae	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
YHH3_k127_12596700_4	675806.VII_000723	7.288e-20	95.0	2E5AU@1|root,3302Y@2|Bacteria,1RFJF@1224|Proteobacteria,1S5HE@1236|Gammaproteobacteria,1XY8I@135623|Vibrionales	135623|Vibrionales	S	Src homology 3 domains	-	-	-	-	-	-	-	-	-	-	-	-	SH3_2
YHH3_k127_1261013_1	382464.ABSI01000011_gene2352	1.537e-52	190.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,2IUGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347,HlyD_D23
YHH3_k127_1261013_0	382464.ABSI01000011_gene2351	0.0	1726.0	COG0841@1|root,COG0841@2|Bacteria,46Z6Y@74201|Verrucomicrobia,2ITZB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_12620341_2	1396418.BATQ01000117_gene4587	2.571e-13	79.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH3_k127_12620341_0	382464.ABSI01000013_gene1633	1.511e-201	649.0	COG2304@1|root,COG2304@2|Bacteria,46XD8@74201|Verrucomicrobia,2IVI0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
YHH3_k127_12620341_1	382464.ABSI01000021_gene439	2.956e-104	355.0	COG3829@1|root,COG3829@2|Bacteria,46Z7D@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
YHH3_k127_12634762_1	382464.ABSI01000020_gene337	3.746e-91	305.0	COG5016@1|root,COG5016@2|Bacteria,46UNW@74201|Verrucomicrobia,2IWQ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	HMGL-like	-	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
YHH3_k127_12634762_0	583355.Caka_1187	2.369e-99	333.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Guanylate_cyc,HAMP,Response_reg,dCache_1
YHH3_k127_12634762_2	290315.Clim_2109	3.546e-28	116.0	COG3654@1|root,COG3654@2|Bacteria	2|Bacteria	-	-	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
YHH3_k127_12693088_1	472759.Nhal_1641	7.27e-60	213.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,1X0Q2@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
YHH3_k127_12693088_0	1267534.KB906754_gene3624	1.364e-214	674.0	COG2146@1|root,COG2871@1|root,COG3239@1|root,COG2146@2|Bacteria,COG2871@2|Bacteria,COG3239@2|Bacteria	2|Bacteria	I	unsaturated fatty acid biosynthetic process	mocD	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase,NAD_binding_1,Rieske
YHH3_k127_12697186_0	331869.BAL199_01794	4.4e-323	1013.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,4BPGC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	V	AcrB/AcrD/AcrF family	ttgE	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
YHH3_k127_12697186_1	1033802.SSPSH_001914	7.042e-75	265.0	COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18990	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH3_k127_12697186_2	382464.ABSI01000014_gene1469	6.016e-09	66.0	COG3291@1|root,COG3291@2|Bacteria,46XT0@74201|Verrucomicrobia,2IWHU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12713838_3	583355.Caka_2352	7.168e-39	149.0	COG1611@1|root,COG1611@2|Bacteria,46T2W@74201|Verrucomicrobia,3K8G4@414999|Opitutae	414999|Opitutae	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH3_k127_12713838_0	1042377.AFPJ01000043_gene860	1.045e-165	542.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,1RP19@1236|Gammaproteobacteria,46429@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	acetyl-CoA hydrolase	-	-	-	ko:K18288	ko00660,map00660	-	R02407,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
YHH3_k127_12713838_2	583355.Caka_1716	1.515e-57	207.0	COG0500@1|root,COG2226@2|Bacteria,46V7S@74201|Verrucomicrobia,3K7ZC@414999|Opitutae	414999|Opitutae	Q	PFAM Methionine biosynthesis MetW protein	-	-	-	-	-	-	-	-	-	-	-	-	MetW
YHH3_k127_12713838_1	794903.OPIT5_09495	1.482e-163	521.0	COG2021@1|root,COG2021@2|Bacteria,46U58@74201|Verrucomicrobia,3K7TJ@414999|Opitutae	414999|Opitutae	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
YHH3_k127_12754727_3	382464.ABSI01000007_gene4132	1.826e-76	261.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,2ITIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH3_k127_12754727_2	1304284.L21TH_1357	4.032e-108	359.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,36EZ7@31979|Clostridiaceae	186801|Clostridia	P	K -dependent Na Ca exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
YHH3_k127_12754727_0	583355.Caka_0908	2.292e-246	769.0	COG0696@1|root,COG0696@2|Bacteria,46U4C@74201|Verrucomicrobia,3K7DS@414999|Opitutae	414999|Opitutae	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
YHH3_k127_12754727_1	857087.Metme_0798	3.893e-205	644.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1SX3B@1236|Gammaproteobacteria,1XDZ9@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
YHH3_k127_12754727_4	794903.OPIT5_13020	2.722e-22	103.0	COG1404@1|root,COG2755@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,46VHC@74201|Verrucomicrobia	2|Bacteria	O	lipolytic protein G-D-S-L family	-	-	3.1.3.6,3.1.4.16	ko:K01119,ko:K20276	ko00230,ko00240,ko02024,map00230,map00240,map02024	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	Lipase_GDSL_2,Peptidase_S8,SLH
YHH3_k127_12779656_3	583355.Caka_1479	5.06e-82	274.0	COG0208@1|root,COG0208@2|Bacteria,46SMW@74201|Verrucomicrobia,3K7VI@414999|Opitutae	414999|Opitutae	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
YHH3_k127_12779656_0	583355.Caka_1478	0.0	1570.0	COG0209@1|root,COG0209@2|Bacteria,46SFJ@74201|Verrucomicrobia,3K76K@414999|Opitutae	414999|Opitutae	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
YHH3_k127_12779656_1	583355.Caka_2413	5.489e-218	681.0	COG0137@1|root,COG0137@2|Bacteria,46SCU@74201|Verrucomicrobia,3K7AT@414999|Opitutae	414999|Opitutae	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
YHH3_k127_12779656_2	452637.Oter_0689	1.511e-111	368.0	COG0078@1|root,COG0078@2|Bacteria,46SA5@74201|Verrucomicrobia,3K73T@414999|Opitutae	414999|Opitutae	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YHH3_k127_12779656_4	278957.ABEA03000040_gene3826	1.546e-79	270.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,3K76X@414999|Opitutae	414999|Opitutae	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH3_k127_12785146_0	886293.Sinac_5718	8.81e-111	371.0	COG3119@1|root,COG3119@2|Bacteria,2IYNT@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YHH3_k127_1280606_0	1137799.GZ78_12135	6.608e-80	280.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,1RN1I@1236|Gammaproteobacteria,1XPCB@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3
YHH3_k127_12827615_1	583355.Caka_1972	1.327e-49	185.0	COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia,3K7XA@414999|Opitutae	414999|Opitutae	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_12827615_0	382464.ABSI01000023_gene552	2.778e-106	352.0	COG0777@1|root,COG0777@2|Bacteria,46SI0@74201|Verrucomicrobia,2IU2Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
YHH3_k127_12827615_2	382464.ABSI01000023_gene553	2.846e-42	158.0	COG0285@1|root,COG0285@2|Bacteria,46SKD@74201|Verrucomicrobia,2ITNW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH3_k127_12833790_0	583355.Caka_2914	2.291e-189	601.0	COG0001@1|root,COG0001@2|Bacteria,46TKU@74201|Verrucomicrobia,3K7DQ@414999|Opitutae	414999|Opitutae	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH3_k127_12833790_1	794903.OPIT5_07035	2.416e-157	516.0	COG0323@1|root,COG3170@1|root,COG0323@2|Bacteria,COG3170@2|Bacteria,46SG5@74201|Verrucomicrobia,3K76S@414999|Opitutae	414999|Opitutae	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
YHH3_k127_12833790_2	243090.RB5178	3.408e-08	57.0	COG0442@1|root,COG0442@2|Bacteria,2IX8V@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b,tRNA_edit
YHH3_k127_12852779_3	626522.GCWU000325_02097	0.0001777	46.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,2FRXW@200643|Bacteroidia	976|Bacteroidetes	GM	NAD dependent epimerase dehydratase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YHH3_k127_12852779_2	1128421.JAGA01000002_gene394	2.7e-65	234.0	COG0463@1|root,COG0463@2|Bacteria,2NQWR@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	ykcC	-	2.4.1.83	ko:K00721,ko:K20534	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
YHH3_k127_12852779_1	1403819.BATR01000185_gene6411	1.814e-94	316.0	COG1208@1|root,COG1208@2|Bacteria,46SQS@74201|Verrucomicrobia,2IVN8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
YHH3_k127_12852779_0	1496688.ER33_14285	1.441e-171	546.0	COG0399@1|root,COG0399@2|Bacteria,1G36Q@1117|Cyanobacteria,22TGZ@167375|Cyanobium	1117|Cyanobacteria	M	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
YHH3_k127_1322201_0	452637.Oter_2955	3.388e-236	741.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	GxGYxYP_C,GxGYxYP_N,Inovirus_Gp2,Sigma70_r4_2
YHH3_k127_1322201_1	382464.ABSI01000010_gene3508	2.116e-107	354.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_1441707_11	452637.Oter_2651	9.978e-25	108.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,3K7QD@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YHH3_k127_1441707_1	583355.Caka_2827	1.755e-117	385.0	COG2908@1|root,COG2908@2|Bacteria,46U19@74201|Verrucomicrobia,3K7GU@414999|Opitutae	414999|Opitutae	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YHH3_k127_1441707_2	1121035.AUCH01000002_gene1548	1.047e-102	347.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,2KURY@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH3_k127_1441707_4	794903.OPIT5_00885	7.849e-76	268.0	COG0324@1|root,COG0324@2|Bacteria,46T1C@74201|Verrucomicrobia,3K7IR@414999|Opitutae	414999|Opitutae	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YHH3_k127_1441707_5	583355.Caka_1097	1.266e-74	275.0	COG0760@1|root,COG0760@2|Bacteria,46T1I@74201|Verrucomicrobia,3K7JC@414999|Opitutae	414999|Opitutae	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
YHH3_k127_1441707_3	583355.Caka_2867	2.638e-79	283.0	COG1295@1|root,COG1295@2|Bacteria,46USV@74201|Verrucomicrobia,3K77Z@414999|Opitutae	414999|Opitutae	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
YHH3_k127_1441707_9	583355.Caka_2868	1.553e-36	149.0	COG4701@1|root,COG4701@2|Bacteria,46W37@74201|Verrucomicrobia,3K86W@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1441707_6	880070.Cycma_3122	4.18e-52	203.0	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes,47QCV@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
YHH3_k127_1441707_0	583355.Caka_2407	6.715e-192	608.0	COG0112@1|root,COG0112@2|Bacteria,46S5I@74201|Verrucomicrobia,3K79I@414999|Opitutae	414999|Opitutae	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
YHH3_k127_1441707_7	5722.XP_001305454.1	3.207e-39	150.0	COG0698@1|root,2S47V@2759|Eukaryota	2759|Eukaryota	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
YHH3_k127_1441707_8	583355.Caka_0386	5.721e-38	148.0	COG0394@1|root,COG0394@2|Bacteria,46W2V@74201|Verrucomicrobia,3K7ZS@414999|Opitutae	414999|Opitutae	T	low molecular weight	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YHH3_k127_1441707_10	1122919.KB905554_gene759	3.836e-30	128.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,26UCZ@186822|Paenibacillaceae	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
YHH3_k127_1459602_1	583355.Caka_2963	3.014e-65	229.0	COG4783@1|root,COG4783@2|Bacteria,46Z3R@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YHH3_k127_1459602_0	583355.Caka_1463	0.0	1123.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,46SFK@74201|Verrucomicrobia,3K7FG@414999|Opitutae	414999|Opitutae	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
YHH3_k127_1459602_4	278957.ABEA03000019_gene1945	1.554e-05	50.0	2B8IX@1|root,321U3@2|Bacteria,46XWD@74201|Verrucomicrobia,3K8GM@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1459602_2	240016.ABIZ01000001_gene755	4.319e-50	184.0	COG2010@1|root,COG2010@2|Bacteria,46SVP@74201|Verrucomicrobia,2IUJ4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	N-terminal domain of cytochrome oxidase-cbb3, FixP	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,FixP_N
YHH3_k127_1462565_6	1150600.ADIARSV_3952	1.979e-10	62.0	COG1267@1|root,COG1267@2|Bacteria,4NP7N@976|Bacteroidetes,1ITK7@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphatidylglycerophosphatase A	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
YHH3_k127_1462565_3	426114.THI_2759	1.979e-44	166.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,1KKZ9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
YHH3_k127_1462565_4	452637.Oter_3849	1.371e-33	132.0	COG3118@1|root,COG3118@2|Bacteria,46VWK@74201|Verrucomicrobia,3K8B4@414999|Opitutae	414999|Opitutae	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YHH3_k127_1462565_2	794903.OPIT5_27540	1.072e-80	276.0	COG1354@1|root,COG1354@2|Bacteria,46UZS@74201|Verrucomicrobia,3K76V@414999|Opitutae	414999|Opitutae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
YHH3_k127_1462565_1	583355.Caka_0933	7.831e-95	337.0	COG1452@1|root,COG1452@2|Bacteria,46SJX@74201|Verrucomicrobia,3K7FX@414999|Opitutae	414999|Opitutae	M	Organic solvent tolerance protein	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
YHH3_k127_1462565_0	583355.Caka_0932	5.074e-321	998.0	COG0296@1|root,COG0296@2|Bacteria,46SH5@74201|Verrucomicrobia,3K74A@414999|Opitutae	414999|Opitutae	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
YHH3_k127_1469381_3	583355.Caka_1951	3.399e-51	188.0	COG1266@1|root,COG1266@2|Bacteria,46XTZ@74201|Verrucomicrobia,3K831@414999|Opitutae	414999|Opitutae	S	Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
YHH3_k127_1469381_1	583355.Caka_2488	2.601e-82	277.0	COG0264@1|root,COG0264@2|Bacteria,46SUK@74201|Verrucomicrobia,3K76T@414999|Opitutae	414999|Opitutae	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
YHH3_k127_1469381_0	583355.Caka_2487	8.23e-95	319.0	COG0052@1|root,COG0052@2|Bacteria,46SNG@74201|Verrucomicrobia,3K7D6@414999|Opitutae	414999|Opitutae	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YHH3_k127_1469381_4	382464.ABSI01000009_gene3934	1.493e-48	190.0	COG0817@1|root,COG0817@2|Bacteria,46T3Y@74201|Verrucomicrobia,2IUA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
YHH3_k127_1469381_2	583355.Caka_1969	3.671e-68	239.0	COG0730@1|root,COG0730@2|Bacteria,46VE4@74201|Verrucomicrobia,3K7RM@414999|Opitutae	414999|Opitutae	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH3_k127_1485111_1	357808.RoseRS_3926	5.118e-112	368.0	COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi,377Z7@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH3_k127_1485111_0	1121324.CLIT_8c01210	3.731e-179	581.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25U26@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
YHH3_k127_1489941_0	1157708.KB907455_gene3461	3.111e-174	556.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,2VHSN@28216|Betaproteobacteria,4AAVS@80864|Comamonadaceae	28216|Betaproteobacteria	O	TIGRFAM type VI secretion ATPase, ClpV1 family	clpV	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH3_k127_1489941_1	330214.NIDE1987	2.576e-56	201.0	COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,3J13S@40117|Nitrospirae	40117|Nitrospirae	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
YHH3_k127_1492084_0	1331060.RLDS_13830	2.73e-10	67.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,2TUIR@28211|Alphaproteobacteria,2K0N7@204457|Sphingomonadales	204457|Sphingomonadales	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH3_k127_1507121_0	1396141.BATP01000022_gene335	4.811e-118	392.0	29RTN@1|root,30CXJ@2|Bacteria,46XB6@74201|Verrucomicrobia,2IV96@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1507121_1	1396141.BATP01000022_gene336	1.736e-98	330.0	2AWPW@1|root,31NKT@2|Bacteria,46WZA@74201|Verrucomicrobia,2IVVN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1507121_2	583355.Caka_2877	1.208e-74	259.0	COG2706@1|root,COG2706@2|Bacteria,46SHH@74201|Verrucomicrobia,3K826@414999|Opitutae	414999|Opitutae	G	6-phosphogluconolactonase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
YHH3_k127_1510255_0	497964.CfE428DRAFT_4597	4.017e-191	615.0	COG4108@1|root,COG4108@2|Bacteria,46SF9@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
YHH3_k127_1510255_2	1089553.Tph_c00550	5.036e-13	74.0	COG1848@1|root,COG1848@2|Bacteria,1VFQN@1239|Firmicutes,24NXI@186801|Clostridia,42GV7@68295|Thermoanaerobacterales	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
YHH3_k127_1510255_1	382464.ABSI01000005_gene1074	1.412e-132	423.0	COG2160@1|root,COG2160@2|Bacteria,46UVN@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
YHH3_k127_1525902_2	583355.Caka_1121	2.203e-95	314.0	COG0524@1|root,COG0524@2|Bacteria,46TGU@74201|Verrucomicrobia,3K7M0@414999|Opitutae	414999|Opitutae	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
YHH3_k127_1525902_0	452637.Oter_4261	2.633e-146	472.0	COG0111@1|root,COG0111@2|Bacteria,46UA8@74201|Verrucomicrobia,3K7HE@414999|Opitutae	414999|Opitutae	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH3_k127_1525902_3	382464.ABSI01000005_gene1051	9.389e-77	270.0	COG1609@1|root,COG1609@2|Bacteria,46U1E@74201|Verrucomicrobia,2IW3R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	-	-	-	-	-	-	-	-	-	GntR,LacI,Peripla_BP_3
YHH3_k127_1525902_1	518766.Rmar_1528	2.4e-117	391.0	2BXG3@1|root,2Z82R@2|Bacteria,4NI3Z@976|Bacteroidetes	976|Bacteroidetes	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
YHH3_k127_1525902_6	472759.Nhal_3484	2.078e-07	56.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH3_k127_1525902_4	933262.AXAM01000024_gene727	1.566e-23	105.0	COG3744@1|root,COG3744@2|Bacteria,1RJ4K@1224|Proteobacteria,42WUI@68525|delta/epsilon subdivisions,2WT5M@28221|Deltaproteobacteria,2MNKV@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_1525902_5	1122138.AQUZ01000100_gene8754	3.851e-12	67.0	COG3744@1|root,COG3744@2|Bacteria,2GSS6@201174|Actinobacteria,4DWER@85009|Propionibacteriales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_1543068_1	794903.OPIT5_14920	1.386e-47	180.0	COG1947@1|root,COG1947@2|Bacteria,46SV6@74201|Verrucomicrobia,3K807@414999|Opitutae	414999|Opitutae	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YHH3_k127_1543068_0	794903.OPIT5_14960	5.733e-76	265.0	COG1080@1|root,COG1080@2|Bacteria,46TX4@74201|Verrucomicrobia,3K7JG@414999|Opitutae	414999|Opitutae	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
YHH3_k127_1546523_0	1469557.JSWF01000021_gene731	1.334e-150	496.0	COG1404@1|root,COG4409@1|root,COG1404@2|Bacteria,COG4409@2|Bacteria,4PM7K@976|Bacteroidetes,1IJKJ@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD
YHH3_k127_1549010_1	243277.VC_A0317	1.202e-27	112.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,1XXE6@135623|Vibrionales	135623|Vibrionales	M	lipoprotein Blc	blc	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
YHH3_k127_1549010_3	1121875.KB907546_gene2701	0.0002689	46.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,1I0HW@117743|Flavobacteriia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
YHH3_k127_1549010_2	1469613.JT55_16420	8.606e-20	99.0	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,2V94B@28211|Alphaproteobacteria,3FEB6@34008|Rhodovulum	28211|Alphaproteobacteria	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
YHH3_k127_1549010_0	298386.PBPRB1406	3.425e-43	161.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XTXC@135623|Vibrionales	135623|Vibrionales	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH3_k127_156202_2	497964.CfE428DRAFT_1462	1.92e-15	82.0	COG0084@1|root,COG0084@2|Bacteria,46SRB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM TatD-related deoxyribonuclease	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YHH3_k127_156202_0	583355.Caka_2501	7.397e-47	173.0	COG2166@1|root,COG2166@2|Bacteria,46W04@74201|Verrucomicrobia,3K88I@414999|Opitutae	414999|Opitutae	S	Fe-S metabolism	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
YHH3_k127_156202_3	1396141.BATP01000040_gene2168	3.48e-06	53.0	2E5AU@1|root,33IMG@2|Bacteria	2|Bacteria	S	Variant SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_1,SH3_2,SH3_4
YHH3_k127_156202_1	583355.Caka_0932	4.885e-26	109.0	COG0296@1|root,COG0296@2|Bacteria,46SH5@74201|Verrucomicrobia,3K74A@414999|Opitutae	414999|Opitutae	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
YHH3_k127_15953_1	335543.Sfum_2415	7.774e-83	282.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2WKHW@28221|Deltaproteobacteria,2MQ9V@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YHH3_k127_15953_0	335543.Sfum_2414	1.893e-91	313.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2WKC7@28221|Deltaproteobacteria,2MQ7Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YHH3_k127_15953_2	1267533.KB906740_gene284	8.731e-69	256.0	COG1505@1|root,COG1505@2|Bacteria,3Y2UH@57723|Acidobacteria,2JHQ3@204432|Acidobacteriia	204432|Acidobacteriia	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
YHH3_k127_1601600_5	583355.Caka_2156	7.894e-28	114.0	COG0804@1|root,COG0804@2|Bacteria,46SB6@74201|Verrucomicrobia,3K74Z@414999|Opitutae	414999|Opitutae	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
YHH3_k127_1601600_4	497964.CfE428DRAFT_4627	3.087e-37	148.0	COG0832@1|root,COG0832@2|Bacteria,46VVC@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
YHH3_k127_1601600_3	382464.ABSI01000013_gene1760	2.943e-49	176.0	COG0831@1|root,COG0831@2|Bacteria,46SW3@74201|Verrucomicrobia,2IWJ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Urease, gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Urease_gamma
YHH3_k127_1601600_2	583355.Caka_2153	3.13e-94	316.0	COG0410@1|root,COG0410@2|Bacteria,46TST@74201|Verrucomicrobia,3K7VH@414999|Opitutae	414999|Opitutae	E	urea ABC transporter, ATP-binding protein	-	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
YHH3_k127_1601600_1	382464.ABSI01000013_gene1764	2.952e-126	407.0	COG4674@1|root,COG4674@2|Bacteria,46SHS@74201|Verrucomicrobia,2ITUB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
YHH3_k127_1601600_0	583355.Caka_2151	2.931e-147	471.0	COG4177@1|root,COG4177@2|Bacteria,46S8E@74201|Verrucomicrobia,3K7EY@414999|Opitutae	414999|Opitutae	P	Urea ABC transporter permease	-	-	-	ko:K11961	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
YHH3_k127_1617124_0	1396141.BATP01000022_gene333	0.0	1683.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1627413_2	382464.ABSI01000013_gene1500	1.54e-23	111.0	COG1595@1|root,COG1595@2|Bacteria,46VME@74201|Verrucomicrobia,2IUQG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_1627413_4	1396418.BATQ01000083_gene1162	4.429e-15	81.0	COG2259@1|root,COG2259@2|Bacteria,46WSE@74201|Verrucomicrobia,2IWGT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	MauE
YHH3_k127_1627413_3	497964.CfE428DRAFT_0575	3.759e-20	95.0	COG0607@1|root,COG0607@2|Bacteria,46T32@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YHH3_k127_1627413_0	583355.Caka_1480	1.741e-44	168.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia,3K9TR@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_1627413_1	794903.OPIT5_27765	1.62e-33	139.0	COG0545@1|root,COG0545@2|Bacteria,46VYS@74201|Verrucomicrobia,3K82D@414999|Opitutae	414999|Opitutae	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
YHH3_k127_1689774_4	204536.SULAZ_1623	2.533e-05	48.0	COG1077@1|root,COG1077@2|Bacteria,2G4KK@200783|Aquificae	200783|Aquificae	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH3_k127_1689774_0	382464.ABSI01000005_gene968	1.969e-118	410.0	COG0475@1|root,COG0475@2|Bacteria,46U4K@74201|Verrucomicrobia,2IV1A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C
YHH3_k127_1689774_2	871968.DESME_01805	1.4e-18	96.0	2DPEU@1|root,331SS@2|Bacteria,1VE8J@1239|Firmicutes,255XC@186801|Clostridia	186801|Clostridia	S	Golgi phosphoprotein 3 (GPP34)	-	-	-	-	-	-	-	-	-	-	-	-	GPP34
YHH3_k127_1689774_1	452637.Oter_2516	1.335e-22	103.0	COG1381@1|root,COG1381@2|Bacteria,46WI8@74201|Verrucomicrobia,3K8H9@414999|Opitutae	414999|Opitutae	L	Involved in DNA repair and RecF pathway recombination	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_1699396_1	382464.ABSI01000021_gene454	2.251e-16	83.0	COG4289@1|root,COG4289@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2264)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2264
YHH3_k127_1699396_0	1265503.KB905161_gene3152	2.822e-170	548.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_1699396_2	382464.ABSI01000010_gene3867	3.015e-08	64.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarboxypepD_reg,Plug,TonB_C
YHH3_k127_1725398_0	452637.Oter_3092	1.676e-218	690.0	COG0855@1|root,COG0855@2|Bacteria,46SB4@74201|Verrucomicrobia,3K74J@414999|Opitutae	414999|Opitutae	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
YHH3_k127_1730489_0	1232437.KL662057_gene3906	6.495e-92	307.0	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2X75Q@28221|Deltaproteobacteria,2MITK@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
YHH3_k127_1730489_1	1232437.KL662057_gene3905	5.115e-85	287.0	COG2191@1|root,COG2191@2|Bacteria,1RBNI@1224|Proteobacteria,42QZP@68525|delta/epsilon subdivisions,2WMY0@28221|Deltaproteobacteria,2MJH4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
YHH3_k127_1730489_2	573370.DMR_37340	7.7e-16	77.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MI4@68525|delta/epsilon subdivisions,2WKB9@28221|Deltaproteobacteria,2M9JS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YHH3_k127_1750771_0	382464.ABSI01000007_gene4148	7.895e-114	379.0	COG1070@1|root,COG1070@2|Bacteria,46S5Z@74201|Verrucomicrobia,2IUPF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.51	ko:K00879	ko00051,ko01120,map00051,map01120	-	R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
YHH3_k127_1750771_1	382464.ABSI01000003_gene4212	6.325e-39	151.0	COG2017@1|root,COG2017@2|Bacteria,46VDK@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
YHH3_k127_1812740_8	870187.Thini_3477	3.625e-07	52.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,4609M@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YHH3_k127_1812740_5	452637.Oter_0696	1.099e-38	148.0	COG0103@1|root,COG0103@2|Bacteria,46VAQ@74201|Verrucomicrobia,3K7ZU@414999|Opitutae	414999|Opitutae	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
YHH3_k127_1812740_3	382464.ABSI01000012_gene2250	1.272e-58	206.0	COG0102@1|root,COG0102@2|Bacteria,46VEU@74201|Verrucomicrobia,2IUBQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YHH3_k127_1812740_2	1403819.BATR01000002_gene80	1.127e-118	390.0	COG0176@1|root,COG0176@2|Bacteria,46UAK@74201|Verrucomicrobia,2ITMF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	TAL_FSA
YHH3_k127_1812740_7	1121406.JAEX01000011_gene2080	5.993e-18	87.0	COG4627@1|root,COG4627@2|Bacteria,1N8RI@1224|Proteobacteria,43BG0@68525|delta/epsilon subdivisions,2X6UB@28221|Deltaproteobacteria,2MH71@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Stress responsive alpha-beta barrel	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
YHH3_k127_1812740_6	481448.Minf_1992	1.873e-32	130.0	COG0366@1|root,COG0366@2|Bacteria,46S7A@74201|Verrucomicrobia,37FYF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
YHH3_k127_1812740_0	478741.JAFS01000001_gene1443	3.08e-195	623.0	COG0366@1|root,COG0366@2|Bacteria,46S7A@74201|Verrucomicrobia,37FYF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
YHH3_k127_1812740_1	497964.CfE428DRAFT_0835	4.778e-174	556.0	COG0297@1|root,COG0297@2|Bacteria,46Z3D@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_1812740_9	760192.Halhy_2936	0.0003761	47.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1INSD@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH3_k127_1859392_0	382464.ABSI01000013_gene1872	2.546e-95	320.0	COG5520@1|root,COG5520@2|Bacteria,46UV5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glycoside hydrolase family 30	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
YHH3_k127_1859392_1	373903.Hore_02670	5.732e-73	253.0	COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes	1239|Firmicutes	G	PFAM glycoside hydrolase, family 16	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_16
YHH3_k127_18876_0	583355.Caka_1571	2.562e-58	209.0	COG2928@1|root,COG2928@2|Bacteria,46ZI5@74201|Verrucomicrobia,3K82R@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
YHH3_k127_18876_1	382464.ABSI01000021_gene368	2.426e-31	128.0	COG0319@1|root,COG0319@2|Bacteria,46WBN@74201|Verrucomicrobia,2IUS4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
YHH3_k127_18876_2	794903.OPIT5_16485	9.036e-31	125.0	COG1480@1|root,COG1480@2|Bacteria,46TM6@74201|Verrucomicrobia,3K7BW@414999|Opitutae	414999|Opitutae	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
YHH3_k127_1902084_0	382464.ABSI01000013_gene1570	1.138e-298	934.0	COG2114@1|root,COG3899@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,46U27@74201|Verrucomicrobia	74201|Verrucomicrobia	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
YHH3_k127_1911272_4	497964.CfE428DRAFT_4350	1.919e-08	59.0	COG1741@1|root,COG1741@2|Bacteria,46SRJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
YHH3_k127_1911272_0	452637.Oter_1408	5.019e-94	325.0	COG0642@1|root,COG2205@2|Bacteria,46SK3@74201|Verrucomicrobia,3K96S@414999|Opitutae	414999|Opitutae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
YHH3_k127_1911272_1	382464.ABSI01000011_gene2364	1.992e-92	314.0	COG0745@1|root,COG0745@2|Bacteria,46SHU@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH3_k127_1911272_2	382464.ABSI01000011_gene2365	4.228e-55	207.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,46VGQ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase, mono-heme subunit/FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
YHH3_k127_1911272_3	452637.Oter_0574	2.37e-10	66.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,46VGQ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase, mono-heme subunit/FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
YHH3_k127_1918318_4	871963.Desdi_1054	5.458e-05	49.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia,262MA@186807|Peptococcaceae	186801|Clostridia	J	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
YHH3_k127_1918318_2	1267533.KB906735_gene4699	2.918e-44	169.0	COG3132@1|root,COG3132@2|Bacteria,3Y50M@57723|Acidobacteria,2JMSB@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
YHH3_k127_1918318_0	452637.Oter_2855	1.741e-103	341.0	COG0745@1|root,COG0745@2|Bacteria,46VWY@74201|Verrucomicrobia,3K7WH@414999|Opitutae	414999|Opitutae	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH3_k127_1918318_3	1304885.AUEY01000008_gene2112	3.373e-32	128.0	COG0140@1|root,COG0140@2|Bacteria	2|Bacteria	E	phosphoribosyl-ATP diphosphatase activity	hisE	GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31,5.3.1.16	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037,R04640	RC00002,RC00945,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186,iYO844.BSU34860	PRA-CH,PRA-PH
YHH3_k127_1918318_1	1304885.AUEY01000008_gene2113	1.351e-99	332.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WIY9@28221|Deltaproteobacteria,2MHVV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
YHH3_k127_193294_1	583355.Caka_1615	3.268e-106	351.0	28MGX@1|root,2ZATZ@2|Bacteria,46TJV@74201|Verrucomicrobia,3K7EP@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_193294_0	382464.ABSI01000011_gene3025	2.847e-153	492.0	COG1186@1|root,COG1186@2|Bacteria,46SAW@74201|Verrucomicrobia,2ITHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH3_k127_193294_3	583355.Caka_2208	9.24e-08	61.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	ycgF	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822	-	ko:K06895	-	-	-	-	ko00000,ko02000	2.A.75.1	-	-	LysE
YHH3_k127_193294_2	243233.MCA1875	6.67e-12	66.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bile acid sodium symporter	yocS	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
YHH3_k127_1947131_0	479434.Sthe_2689	1.495e-131	423.0	COG1454@1|root,COG1454@2|Bacteria,2G6IU@200795|Chloroflexi,27YUC@189775|Thermomicrobia	189775|Thermomicrobia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.99.24	ko:K11173	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
YHH3_k127_1947131_1	639030.JHVA01000001_gene114	6.801e-29	116.0	COG1012@1|root,COG1012@2|Bacteria,3Y2RN@57723|Acidobacteria,2JKDB@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH3_k127_1960631_5	583355.Caka_1062	2.762e-178	562.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,3K7MH@414999|Opitutae	414999|Opitutae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YHH3_k127_1960631_7	452637.Oter_2677	3.986e-117	390.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia,3K7PV@414999|Opitutae	414999|Opitutae	H	Protein-arginine kinase	-	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
YHH3_k127_1960631_12	452637.Oter_2676	3.468e-61	215.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia,3K823@414999|Opitutae	414999|Opitutae	S	UvrB/uvrC motif	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
YHH3_k127_1960631_6	583355.Caka_1065	3.328e-130	421.0	COG0115@1|root,COG0115@2|Bacteria,46S9W@74201|Verrucomicrobia,3K7I4@414999|Opitutae	414999|Opitutae	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YHH3_k127_1960631_10	583355.Caka_1520	5.93e-75	259.0	COG0483@1|root,COG0483@2|Bacteria,46VJG@74201|Verrucomicrobia,3K83G@414999|Opitutae	414999|Opitutae	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YHH3_k127_1960631_11	452637.Oter_2818	1.583e-74	262.0	COG0196@1|root,COG0196@2|Bacteria,46UCC@74201|Verrucomicrobia,3K7G1@414999|Opitutae	414999|Opitutae	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
YHH3_k127_1960631_9	382464.ABSI01000010_gene3686	7.573e-92	308.0	COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,2ITQ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
YHH3_k127_1960631_8	583355.Caka_1793	2.477e-111	368.0	COG0618@1|root,COG0618@2|Bacteria,46T03@74201|Verrucomicrobia,3K7K6@414999|Opitutae	414999|Opitutae	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YHH3_k127_1960631_15	1499967.BAYZ01000115_gene2917	4.094e-07	57.0	COG0858@1|root,COG0858@2|Bacteria,2NQ7B@2323|unclassified Bacteria	2|Bacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
YHH3_k127_1960631_2	452637.Oter_2814	8.179e-237	757.0	COG0532@1|root,COG0532@2|Bacteria,46S8V@74201|Verrucomicrobia,3K79C@414999|Opitutae	414999|Opitutae	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
YHH3_k127_1960631_4	583355.Caka_1796	1.28e-180	574.0	COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia,3K7UP@414999|Opitutae	414999|Opitutae	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
YHH3_k127_1960631_13	382464.ABSI01000010_gene3691	1.402e-58	219.0	28HQ3@1|root,2Z7XW@2|Bacteria,46U81@74201|Verrucomicrobia,2ITXI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
YHH3_k127_1960631_16	1382306.JNIM01000001_gene726	0.0002561	51.0	COG3688@1|root,COG3688@2|Bacteria	2|Bacteria	D	RNA-binding protein containing a PIN domain	yacP	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_IV,GTP_EFTU,NYN_YacP
YHH3_k127_1960631_3	278957.ABEA03000174_gene3439	3.338e-196	627.0	COG1227@1|root,COG4109@1|root,COG1227@2|Bacteria,COG4109@2|Bacteria,46UKX@74201|Verrucomicrobia,3K7M6@414999|Opitutae	414999|Opitutae	CK	DHHA2	-	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
YHH3_k127_1960631_1	382464.ABSI01000023_gene546	1.209e-247	787.0	COG0557@1|root,COG0557@2|Bacteria,46U8T@74201|Verrucomicrobia,2ITHQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
YHH3_k127_1960631_0	794903.OPIT5_18285	0.0	1064.0	COG0567@1|root,COG0567@2|Bacteria,46S6G@74201|Verrucomicrobia,3K743@414999|Opitutae	414999|Opitutae	C	2-oxoglutarate dehydrogenase C-terminal	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
YHH3_k127_1960631_14	382464.ABSI01000005_gene1108	5.344e-27	113.0	COG0508@1|root,COG0508@2|Bacteria,46SD3@74201|Verrucomicrobia,2ITTQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl
YHH3_k127_1986138_0	1121405.dsmv_2119	0.0	1143.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MIDR@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH3_k127_1986138_1	1232410.KI421416_gene2561	1.95e-89	302.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
YHH3_k127_2015312_0	1357279.N018_07610	3.384e-74	257.0	COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1Z6CJ@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	C	Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate	astD	GO:0003674,GO:0003824,GO:0004029,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c20030,iEcHS_1320.EcHS_A1829,ic_1306.c2146	Aldedh
YHH3_k127_2015312_1	1122201.AUAZ01000006_gene4000	1.079e-65	235.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,4661T@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG3138 Arginine ornithine N-succinyltransferase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	AstA
YHH3_k127_2029230_1	1396141.BATP01000020_gene108	3.158e-126	440.0	COG2312@1|root,COG4870@1|root,COG2312@2|Bacteria,COG4870@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
YHH3_k127_2029230_3	1340434.AXVA01000022_gene4044	0.0003365	45.0	2DFW2@1|root,2ZTE1@2|Bacteria,1W5BA@1239|Firmicutes,4IM45@91061|Bacilli,1ZJ3K@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2029230_0	96561.Dole_1813	9.313e-160	511.0	COG1373@1|root,COG1373@2|Bacteria,1NQGE@1224|Proteobacteria,42R19@68525|delta/epsilon subdivisions,2WMNW@28221|Deltaproteobacteria,2MMR8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
YHH3_k127_2029230_2	794903.OPIT5_08600	1.736e-28	124.0	COG0168@1|root,COG0168@2|Bacteria,46U92@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
YHH3_k127_2051766_0	633149.Bresu_1345	1.319e-61	223.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TRTW@28211|Alphaproteobacteria,2KFTK@204458|Caulobacterales	204458|Caulobacterales	E	Peptidase, M20	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YHH3_k127_2051766_1	583355.Caka_0836	2.883e-35	139.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia,3K75G@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_2094238_1	744872.Spica_0824	1.133e-21	101.0	COG2273@1|root,COG2273@2|Bacteria,2J7RN@203691|Spirochaetes	203691|Spirochaetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
YHH3_k127_2094238_2	518766.Rmar_2566	1.204e-16	82.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015684,GO:0030001,GO:0033554,GO:0034220,GO:0034755,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070627,GO:0070838,GO:0072511,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098707,GO:0098711,GO:0098739,GO:0099587,GO:1903874	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
YHH3_k127_2094238_0	452637.Oter_0871	4.966e-66	232.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
YHH3_k127_2131810_2	583355.Caka_2271	2.097e-42	166.0	2E0WS@1|root,32WDT@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
YHH3_k127_2131810_0	382464.ABSI01000012_gene2058	5.425e-108	368.0	COG0811@1|root,COG0811@2|Bacteria,46UAW@74201|Verrucomicrobia,2IVTF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
YHH3_k127_2131810_3	382464.ABSI01000007_gene4062	1.74e-36	145.0	COG0811@1|root,COG0811@2|Bacteria,46VPT@74201|Verrucomicrobia,2IWJ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
YHH3_k127_2131810_1	382464.ABSI01000012_gene2056	5.951e-48	175.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH3_k127_2131810_4	382464.ABSI01000007_gene4060	5.922e-15	79.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH3_k127_21547_5	278957.ABEA03000143_gene1053	4.353e-49	179.0	COG0337@1|root,COG0337@2|Bacteria,46SRE@74201|Verrucomicrobia,3K7IX@414999|Opitutae	414999|Opitutae	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
YHH3_k127_21547_7	1220534.B655_0766	2.163e-33	138.0	COG0500@1|root,arCOG01402@2157|Archaea,2XYWP@28890|Euryarchaeota	28890|Euryarchaeota	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
YHH3_k127_21547_2	1128912.GMES_3022	1.504e-86	298.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RTS0@1236|Gammaproteobacteria,4655R@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	lpcC	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_21547_1	713586.KB900536_gene1793	2.13e-87	304.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1WXE3@135613|Chromatiales	135613|Chromatiales	G	PFAM Fructosamine	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
YHH3_k127_21547_0	452637.Oter_0006	4.661e-95	329.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616,Exo_endo_phos
YHH3_k127_21547_4	1211813.CAPH01000007_gene1878	2.808e-52	188.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,2FM80@200643|Bacteroidia	976|Bacteroidetes	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YHH3_k127_21547_3	794903.OPIT5_28635	1.318e-52	201.0	COG1385@1|root,COG1385@2|Bacteria,46V87@74201|Verrucomicrobia,3K833@414999|Opitutae	414999|Opitutae	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
YHH3_k127_21547_6	452637.Oter_0683	2.423e-47	177.0	COG0742@1|root,COG0742@2|Bacteria,46VKM@74201|Verrucomicrobia,3K8B1@414999|Opitutae	414999|Opitutae	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
YHH3_k127_2176826_3	382464.ABSI01000010_gene3554	5.487e-56	198.0	COG3959@1|root,COG3959@2|Bacteria	2|Bacteria	G	transketolase activity	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YHH3_k127_2176826_1	382464.ABSI01000010_gene3553	3.263e-136	441.0	COG3958@1|root,COG3958@2|Bacteria	2|Bacteria	G	transketolase activity	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
YHH3_k127_2176826_2	1231241.Mc24_06713	1.724e-132	438.0	COG0554@1|root,COG0554@2|Bacteria,2GC7B@200918|Thermotogae	200918|Thermotogae	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
YHH3_k127_2176826_0	714943.Mucpa_6740	4.214e-212	677.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,1IPRQ@117747|Sphingobacteriia	976|Bacteroidetes	S	glycosyl hydrolase of	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
YHH3_k127_2253083_1	1396141.BATP01000003_gene5226	2.353e-125	413.0	COG0369@1|root,COG0369@2|Bacteria,46USZ@74201|Verrucomicrobia,2ITQZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1
YHH3_k127_2253083_4	653733.Selin_1030	8.365e-66	228.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Hydrolase_3,Pro_isomerase
YHH3_k127_2253083_5	485913.Krac_8114	7.155e-36	147.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
YHH3_k127_2253083_0	502025.Hoch_6864	4.492e-136	453.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2Z1IJ@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YHH3_k127_2253083_3	1123070.KB899259_gene1967	3.212e-99	334.0	COG0042@1|root,COG0042@2|Bacteria,46SIG@74201|Verrucomicrobia,2ITHJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
YHH3_k127_2253083_2	794903.OPIT5_15105	2.152e-121	423.0	COG1074@1|root,COG1074@2|Bacteria,46SF0@74201|Verrucomicrobia,3K7V5@414999|Opitutae	414999|Opitutae	L	PD-(D/E)XK nuclease superfamily	-	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH3_k127_2263278_1	382464.ABSI01000012_gene1972	8.995e-100	330.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46URT@74201|Verrucomicrobia,2IV35@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
YHH3_k127_2263278_0	886293.Sinac_4290	9.407e-114	378.0	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
YHH3_k127_2270572_0	237609.PSAKL28_31720	6.364e-297	927.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,1RZMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH3_k127_2270572_1	378806.STAUR_1477	6.733e-12	74.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria,2YWK2@29|Myxococcales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
YHH3_k127_2272042_4	452637.Oter_1358	9.63e-32	128.0	COG3254@1|root,COG3254@2|Bacteria,46XUW@74201|Verrucomicrobia,3K8BE@414999|Opitutae	414999|Opitutae	J	Involved in the anomeric conversion of L-rhamnose	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
YHH3_k127_2272042_0	1328313.DS2_07733	3.936e-226	707.0	COG2407@1|root,COG2407@2|Bacteria,1R5ZQ@1224|Proteobacteria,1RNGR@1236|Gammaproteobacteria,469P5@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	L-fucose isomerase, C-terminal domain	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Isome,Fucose_iso_C
YHH3_k127_2272042_5	1123256.KB907935_gene2501	2.735e-05	50.0	COG0697@1|root,2Z7ID@2|Bacteria,1MXB3@1224|Proteobacteria,1RQV6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system)	rhaT	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015291,GO:0015293,GO:0015749,GO:0015762,GO:0016020,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	iECSE_1348.ECSE_4196,iEcE24377_1341.EcE24377A_4438,iYL1228.KPN_04216	RhaT
YHH3_k127_2272042_2	665956.HMPREF1032_00843	4.879e-74	271.0	28MYJ@1|root,2ZB5F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2272042_1	665956.HMPREF1032_00843	3.033e-76	280.0	28MYJ@1|root,2ZB5F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2277772_2	1499967.BAYZ01000074_gene2193	8.812e-109	367.0	COG1884@1|root,COG1884@2|Bacteria,2NQRE@2323|unclassified Bacteria	2|Bacteria	I	Methylmalonyl-CoA mutase	mutA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944	2.7.7.7,5.4.99.2,5.4.99.63	ko:K01847,ko:K03763,ko:K14447	ko00230,ko00240,ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,ko03030,ko03430,ko03440,map00230,map00240,map00280,map00630,map00640,map00720,map01100,map01120,map01200,map03030,map03430,map03440	M00260,M00373,M00376,M00741	R00375,R00376,R00377,R00378,R00833,R09292	RC00395,RC02795,RC02835	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	MM_CoA_mutase
YHH3_k127_2277772_0	649747.HMPREF0083_06147	0.0	1105.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,2726S@186822|Paenibacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
YHH3_k127_2277772_1	649747.HMPREF0083_06146	4.895e-137	443.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H9ZJ@91061|Bacilli,2721C@186822|Paenibacillaceae	91061|Bacilli	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
YHH3_k127_2295063_2	382464.ABSI01000011_gene2552	5.727e-13	72.0	COG0546@1|root,COG0546@2|Bacteria,46WZP@74201|Verrucomicrobia,2IUMS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH3_k127_2295063_0	404380.Gbem_0056	1.208e-123	409.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2WK37@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_2295063_1	583355.Caka_2391	8.121e-83	289.0	COG0795@1|root,COG0795@2|Bacteria,46STR@74201|Verrucomicrobia,3K762@414999|Opitutae	414999|Opitutae	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
YHH3_k127_2308197_0	1174528.JH992898_gene3506	1.613e-187	602.0	COG5421@1|root,COG5421@2|Bacteria,1G3YW@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH3_k127_2308197_1	661478.OP10G_3900	9.202e-05	45.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
YHH3_k127_2310097_10	55529.EKX34994	9.514e-23	101.0	COG0476@1|root,KOG2017@2759|Eukaryota	2759|Eukaryota	H	thiosulfate sulfurtransferase activity	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0009719,GO:0009725,GO:0009735,GO:0010033,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rotamase,Rotamase_3
YHH3_k127_2310097_1	583355.Caka_2492	3.802e-136	443.0	COG0836@1|root,COG0836@2|Bacteria,46UR9@74201|Verrucomicrobia,3K7G3@414999|Opitutae	414999|Opitutae	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
YHH3_k127_2310097_7	278957.ABEA03000200_gene4373	4.78e-51	186.0	COG0816@1|root,COG0816@2|Bacteria,46T51@74201|Verrucomicrobia,3K84M@414999|Opitutae	414999|Opitutae	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
YHH3_k127_2310097_4	794903.OPIT5_19920	7.924e-80	273.0	COG0101@1|root,COG0101@2|Bacteria,46SSV@74201|Verrucomicrobia,3K80Q@414999|Opitutae	414999|Opitutae	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
YHH3_k127_2310097_2	497964.CfE428DRAFT_1142	3.517e-118	397.0	COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
YHH3_k127_2310097_8	765912.Thimo_2512	8.211e-49	186.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,1T1Q3@1236|Gammaproteobacteria,1WXCI@135613|Chromatiales	135613|Chromatiales	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
YHH3_k127_2310097_6	706587.Desti_3518	1.077e-62	224.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria,2MRMY@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
YHH3_k127_2310097_3	1121403.AUCV01000010_gene1389	1.37e-83	288.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria,2MIQY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
YHH3_k127_2310097_0	382464.ABSI01000009_gene3929	1.399e-230	725.0	COG0119@1|root,COG0119@2|Bacteria,46TI3@74201|Verrucomicrobia,2ITRE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	HMGL-like	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like,LeuA_dimer
YHH3_k127_2310097_11	1536769.P40081_06640	2.402e-07	60.0	COG1714@1|root,COG1714@2|Bacteria,1TYIU@1239|Firmicutes,4I7PB@91061|Bacilli,26X4V@186822|Paenibacillaceae	91061|Bacilli	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
YHH3_k127_2310097_5	583355.Caka_1595	2.242e-64	225.0	COG0452@1|root,COG0452@2|Bacteria,46SPU@74201|Verrucomicrobia,3K88J@414999|Opitutae	414999|Opitutae	H	Flavoprotein	-	-	4.1.1.36	ko:K01598	ko00770,ko01100,map00770,map01100	M00120	R03269	RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
YHH3_k127_2310097_9	1129374.AJE_06451	3.889e-26	118.0	COG2430@1|root,COG2430@2|Bacteria,1REND@1224|Proteobacteria,1S94F@1236|Gammaproteobacteria,4681T@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF432
YHH3_k127_2310097_12	889378.Spiaf_2499	4.346e-05	49.0	COG0668@1|root,COG0668@2|Bacteria,2J6IE@203691|Spirochaetes	203691|Spirochaetes	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
YHH3_k127_2320853_2	583355.Caka_1477	1.725e-13	72.0	COG2197@1|root,COG2197@2|Bacteria,46T2B@74201|Verrucomicrobia,3K7X9@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_2320853_1	382464.ABSI01000012_gene2078	3.65e-47	182.0	COG0194@1|root,COG0194@2|Bacteria,46SQG@74201|Verrucomicrobia,2IU9Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Guanylate kinase homologues.	-	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
YHH3_k127_2320853_0	583355.Caka_2053	2.831e-108	355.0	COG1674@1|root,COG1674@2|Bacteria,46SCV@74201|Verrucomicrobia,3K7AY@414999|Opitutae	414999|Opitutae	D	FtsK/SpoIIIE family	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YHH3_k127_2326676_12	794903.OPIT5_22620	4.044e-06	51.0	COG2993@1|root,COG2993@2|Bacteria,46T1F@74201|Verrucomicrobia,3K82J@414999|Opitutae	414999|Opitutae	C	cytochrome c oxidase	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
YHH3_k127_2326676_2	583355.Caka_0025	6.079e-218	685.0	COG3278@1|root,COG3278@2|Bacteria,46T64@74201|Verrucomicrobia,3K7FT@414999|Opitutae	414999|Opitutae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
YHH3_k127_2326676_11	278957.ABEA03000189_gene963	8.341e-12	68.0	2BR54@1|root,32K34@2|Bacteria,46YK7@74201|Verrucomicrobia,3K9RT@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2326676_14	452637.Oter_3929	0.0002922	49.0	2B8Q9@1|root,321ZW@2|Bacteria,46XX6@74201|Verrucomicrobia,3K8IF@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2326676_4	583355.Caka_0022	2.83e-130	429.0	COG4531@1|root,COG4531@2|Bacteria,46SME@74201|Verrucomicrobia,3K79U@414999|Opitutae	414999|Opitutae	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2326676_8	497964.CfE428DRAFT_2221	1.965e-48	182.0	COG2010@1|root,COG2010@2|Bacteria,46SV4@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YHH3_k127_2326676_7	278957.ABEA03000189_gene959	2.812e-64	224.0	COG2010@1|root,COG2010@2|Bacteria,46V1P@74201|Verrucomicrobia,3K7WS@414999|Opitutae	414999|Opitutae	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YHH3_k127_2326676_1	278957.ABEA03000189_gene958	7.185e-256	796.0	COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,3K751@414999|Opitutae	414999|Opitutae	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
YHH3_k127_2326676_0	452637.Oter_3934	0.0	1189.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	414999|Opitutae	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
YHH3_k127_2326676_5	583355.Caka_0017	1.691e-99	328.0	COG3880@1|root,COG3880@2|Bacteria,46SMN@74201|Verrucomicrobia,3K7MX@414999|Opitutae	414999|Opitutae	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
YHH3_k127_2326676_3	583355.Caka_0015	7.431e-132	444.0	COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,3K8SD@414999|Opitutae	414999|Opitutae	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
YHH3_k127_2326676_10	1122621.ATZA01000052_gene26	1.436e-13	76.0	COG2259@1|root,COG2259@2|Bacteria,4NTM8@976|Bacteroidetes,1ITB2@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
YHH3_k127_2326676_9	471854.Dfer_5749	1.179e-41	167.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
YHH3_k127_2326676_6	305900.GV64_01235	4.859e-87	296.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,1RSMJ@1236|Gammaproteobacteria,1XND5@135619|Oceanospirillales	135619|Oceanospirillales	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	-	-	-	-	-	-	-	-	-	-	OMPdecase
YHH3_k127_2349091_1	382464.ABSI01000005_gene1144	8.929e-108	358.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia,2IU74@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_2349091_0	382464.ABSI01000005_gene1143	4.181e-140	460.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia,2IU74@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_2349091_2	313628.LNTAR_07789	1.32e-40	153.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	suhB	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
YHH3_k127_2349743_1	62928.azo1604	8.71e-114	372.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,2KV93@206389|Rhodocyclales	206389|Rhodocyclales	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
YHH3_k127_2349743_0	382464.ABSI01000011_gene2679	2.86e-222	717.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,46TPA@74201|Verrucomicrobia,2IU1D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
YHH3_k127_2376052_0	452637.Oter_1890	3.699e-168	557.0	COG0577@1|root,COG0577@2|Bacteria,46UZM@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_2376052_1	911239.CF149_05639	9.227e-14	81.0	COG1538@1|root,COG1538@2|Bacteria,1MWQK@1224|Proteobacteria,1RSGP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_2388087_1	765420.OSCT_1978	1.231e-87	299.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	dhmA	-	3.8.1.5,6.1.3.1	ko:K01563,ko:K22318,ko:K22319	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Abhydrolase_1,Abhydrolase_6
YHH3_k127_2388087_0	452637.Oter_3276	4.669e-180	577.0	COG1640@1|root,COG1640@2|Bacteria,46SX0@74201|Verrucomicrobia,3K7CI@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
YHH3_k127_2388087_4	754477.Q7C_198	2.149e-33	135.0	COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,1T0AA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer Membrane Lipoprotein	blc4	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
YHH3_k127_2388087_2	278957.ABEA03000203_gene2704	6.188e-63	223.0	COG0225@1|root,COG0225@2|Bacteria,46VCK@74201|Verrucomicrobia,3K83N@414999|Opitutae	414999|Opitutae	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
YHH3_k127_2388087_3	583355.Caka_2353	4.888e-41	153.0	COG1196@1|root,COG1196@2|Bacteria,46TT8@74201|Verrucomicrobia,3K7E6@414999|Opitutae	414999|Opitutae	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YHH3_k127_2401148_2	583355.Caka_1849	5.786e-153	488.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia,3K756@414999|Opitutae	414999|Opitutae	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH3_k127_2401148_0	583355.Caka_1850	1.024e-203	642.0	COG0304@1|root,COG0304@2|Bacteria,46V0S@74201|Verrucomicrobia,3K7MU@414999|Opitutae	414999|Opitutae	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH3_k127_2401148_6	452637.Oter_3287	4.496e-37	141.0	COG0236@1|root,COG0236@2|Bacteria,46W39@74201|Verrucomicrobia,3K88G@414999|Opitutae	414999|Opitutae	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
YHH3_k127_2401148_1	452637.Oter_3286	1.219e-159	516.0	COG1233@1|root,COG1233@2|Bacteria,46TRV@74201|Verrucomicrobia,3K78Y@414999|Opitutae	414999|Opitutae	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
YHH3_k127_2401148_4	583355.Caka_0905	1.018e-76	264.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YHH3_k127_2401148_5	452652.KSE_70850	1.617e-67	241.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,2M071@2063|Kitasatospora	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
YHH3_k127_2401148_3	583355.Caka_1955	8.297e-149	477.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia,3K7S9@414999|Opitutae	414999|Opitutae	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YHH3_k127_2430417_0	452637.Oter_2899	2.553e-201	640.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	GxGYxYP_C,GxGYxYP_N,Inovirus_Gp2,Sigma70_r4_2
YHH3_k127_2431286_1	583355.Caka_1390	4.101e-49	186.0	COG3494@1|root,COG3494@2|Bacteria,46SJ6@74201|Verrucomicrobia,3K77G@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
YHH3_k127_2431286_0	794903.OPIT5_17985	0.0	1132.0	COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia,3K736@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
YHH3_k127_2431286_2	794903.OPIT5_17990	7.696e-40	155.0	COG0265@1|root,COG0265@2|Bacteria,46X1C@74201|Verrucomicrobia,3K7EQ@414999|Opitutae	414999|Opitutae	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH3_k127_2443013_1	583355.Caka_2960	7.828e-49	180.0	28HY3@1|root,2Z83I@2|Bacteria,46U77@74201|Verrucomicrobia,3K7PJ@414999|Opitutae	414999|Opitutae	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
YHH3_k127_2443013_0	765913.ThidrDRAFT_1061	1.761e-95	331.0	COG2340@1|root,COG5549@1|root,COG2340@2|Bacteria,COG5549@2|Bacteria,1RJVF@1224|Proteobacteria,1SB6V@1236|Gammaproteobacteria,1X2BX@135613|Chromatiales	1236|Gammaproteobacteria	O	Domain of unknown function (DUF4214)	-	-	-	-	-	-	-	-	-	-	-	-	CAP,DUF4214
YHH3_k127_2449287_2	1336208.JADY01000033_gene4060	1.804e-27	116.0	COG1082@1|root,COG1082@2|Bacteria,1NVM6@1224|Proteobacteria,2USA2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_2449287_1	595460.RRSWK_03706	6.854e-91	306.0	COG1028@1|root,COG1028@2|Bacteria,2IZ8T@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH3_k127_2449287_0	382464.ABSI01000021_gene449	7.574e-102	342.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,GntR,LacI,Peripla_BP_3
YHH3_k127_2451234_0	485913.Krac_1423	6.078e-58	213.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,LZ_Tnp_IS481,rve_3
YHH3_k127_2451234_1	1047013.AQSP01000130_gene1851	2.798e-46	174.0	COG1453@1|root,COG1453@2|Bacteria,2NNZZ@2323|unclassified Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
YHH3_k127_2477789_0	1033732.CAHI01000022_gene1516	5.491e-170	549.0	COG3119@1|root,COG3533@1|root,COG3119@2|Bacteria,COG3533@2|Bacteria,4NF1X@976|Bacteroidetes,2G20J@200643|Bacteroidia,22VAP@171550|Rikenellaceae	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
YHH3_k127_2523696_0	1121447.JONL01000010_gene2381	8.062e-115	377.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42R3Z@68525|delta/epsilon subdivisions,2WN4D@28221|Deltaproteobacteria,2MGMW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
YHH3_k127_2523696_1	583355.Caka_2939	2.264e-84	291.0	COG3547@1|root,COG3547@2|Bacteria,46SUI@74201|Verrucomicrobia,3K9PW@414999|Opitutae	414999|Opitutae	L	transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
YHH3_k127_253047_0	583355.Caka_2960	2.797e-271	848.0	28HY3@1|root,2Z83I@2|Bacteria,46U77@74201|Verrucomicrobia,3K7PJ@414999|Opitutae	414999|Opitutae	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
YHH3_k127_254787_2	1254432.SCE1572_38245	8.582e-08	64.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1P2CI@1224|Proteobacteria	1224|Proteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
YHH3_k127_254787_0	583355.Caka_1488	4.089e-156	506.0	COG0702@1|root,COG0702@2|Bacteria,46W7M@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
YHH3_k127_254787_1	617140.AJZE01000072_gene826	4.376e-25	109.0	COG2356@1|root,COG2356@2|Bacteria,1R4W1@1224|Proteobacteria,1RPZG@1236|Gammaproteobacteria,1XU6X@135623|Vibrionales	135623|Vibrionales	L	COG2356 Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1
YHH3_k127_2556891_5	1454004.AW11_02027	2.72e-06	54.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	sohA	GO:0001558,GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040008,GO:0042802,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K19156	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin,PrlF_antitoxin
YHH3_k127_2556891_3	1454004.AW11_02028	1.235e-18	91.0	2DS2U@1|root,33E9F@2|Bacteria,1PAXB@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
YHH3_k127_2556891_0	1123054.KB907734_gene2636	9.656e-157	501.0	COG0778@1|root,COG0778@2|Bacteria,1NTK9@1224|Proteobacteria,1S1PQ@1236|Gammaproteobacteria,1WY04@135613|Chromatiales	135613|Chromatiales	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2556891_4	234267.Acid_7166	1.05e-14	82.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
YHH3_k127_2556891_1	1283300.ATXB01000002_gene2888	1.275e-43	168.0	2DP87@1|root,330Z8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2623267_2	452637.Oter_4245	1.863e-49	188.0	2A4RK@1|root,30TD0@2|Bacteria,46YHS@74201|Verrucomicrobia,3K9M1@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2623267_0	452637.Oter_2702	8.767e-107	362.0	COG1092@1|root,COG1092@2|Bacteria,46SJ5@74201|Verrucomicrobia,3K84I@414999|Opitutae	414999|Opitutae	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
YHH3_k127_2623267_1	583355.Caka_0245	3.341e-94	321.0	COG0795@1|root,COG0795@2|Bacteria,46T0M@74201|Verrucomicrobia,3K73D@414999|Opitutae	414999|Opitutae	S	PFAM permease YjgP YjgQ family protein	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
YHH3_k127_2623267_3	452637.Oter_3506	2.889e-07	53.0	COG0553@1|root,COG0553@2|Bacteria,46TSJ@74201|Verrucomicrobia,3K74S@414999|Opitutae	414999|Opitutae	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH3_k127_2630792_1	382464.ABSI01000005_gene1295	3.761e-56	201.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YHH3_k127_2630792_0	382464.ABSI01000005_gene1296	1.342e-102	344.0	COG0457@1|root,COG0515@1|root,COG3291@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3291@2|Bacteria,46UMT@74201|Verrucomicrobia,2IVH7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PEGA,PG_binding_1,Pkinase
YHH3_k127_2639855_0	1408473.JHXO01000004_gene207	5.155e-122	404.0	COG1453@1|root,COG1453@2|Bacteria,4NGCW@976|Bacteroidetes,2FPG8@200643|Bacteroidia	976|Bacteroidetes	S	Tat pathway signal sequence domain protein	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
YHH3_k127_2673728_0	583355.Caka_1054	9.829e-93	311.0	COG2262@1|root,COG2262@2|Bacteria,46SP4@74201|Verrucomicrobia,3K7S8@414999|Opitutae	414999|Opitutae	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YHH3_k127_2673728_1	1165096.ARWF01000001_gene60	1.084e-92	321.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VPRI@28216|Betaproteobacteria,2KKCP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH3_k127_2740334_1	452637.Oter_2848	1.903e-55	200.0	COG1051@1|root,COG1051@2|Bacteria,46V5B@74201|Verrucomicrobia,3K7WB@414999|Opitutae	414999|Opitutae	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YHH3_k127_2740334_0	1396418.BATQ01000001_gene1299	1.589e-134	435.0	COG1071@1|root,COG1071@2|Bacteria,46S69@74201|Verrucomicrobia,2ITVF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Transketolase, thiamine diphosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh
YHH3_k127_2745953_1	382464.ABSI01000005_gene1215	8.016e-69	246.0	COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia,2ITGE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YHH3_k127_2745953_0	318586.Pden_0660	3.225e-182	586.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2PUGP@265|Paracoccus	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YHH3_k127_2747682_4	765912.Thimo_1141	8.304e-06	54.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1WWAE@135613|Chromatiales	135613|Chromatiales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YHH3_k127_2747682_3	1122176.KB903539_gene1307	1.299e-08	65.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,1IZ7F@117747|Sphingobacteriia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
YHH3_k127_2747682_1	583355.Caka_1068	1.043e-119	389.0	COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia,3K75T@414999|Opitutae	414999|Opitutae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YHH3_k127_2747682_0	583355.Caka_1067	4.089e-260	813.0	COG4289@1|root,COG4289@2|Bacteria,46UB4@74201|Verrucomicrobia,3K7DP@414999|Opitutae	414999|Opitutae	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2747682_2	530564.Psta_3181	1.767e-108	362.0	COG1158@1|root,COG1158@2|Bacteria,2IXBX@203682|Planctomycetes	203682|Planctomycetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
YHH3_k127_2756516_4	1236514.BAKL01000031_gene2715	0.0005772	48.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,2FWA9@200643|Bacteroidia,4ATB4@815|Bacteroidaceae	976|Bacteroidetes	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_2756516_1	1254432.SCE1572_20550	3.093e-140	452.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,42M9R@68525|delta/epsilon subdivisions,2WKQM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	TRAP dicarboxylate transporter, DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
YHH3_k127_2756516_2	1254432.SCE1572_20555	7.231e-45	168.0	COG3090@1|root,COG3090@2|Bacteria,1PJMJ@1224|Proteobacteria,42XS6@68525|delta/epsilon subdivisions,2WSJP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
YHH3_k127_2756516_0	1254432.SCE1572_20560	1.596e-184	585.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria	1224|Proteobacteria	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
YHH3_k127_2756516_3	278957.ABEA03000091_gene665	4.302e-07	60.0	2A31B@1|root,30RG3@2|Bacteria,46YH8@74201|Verrucomicrobia,3K9KB@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2758234_4	1499967.BAYZ01000111_gene2952	1.664e-23	103.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
YHH3_k127_2758234_1	794903.OPIT5_10645	8.364e-73	256.0	COG1943@1|root,COG1943@2|Bacteria,46V2P@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH3_k127_2758234_3	794903.OPIT5_22565	2.327e-31	128.0	COG0848@1|root,COG0848@2|Bacteria,46WER@74201|Verrucomicrobia,3K80N@414999|Opitutae	414999|Opitutae	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH3_k127_2758234_2	583355.Caka_1361	1.525e-56	204.0	COG0811@1|root,COG0811@2|Bacteria,46VC6@74201|Verrucomicrobia,3K7Z8@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH3_k127_2758234_0	452637.Oter_2681	1.05e-81	275.0	COG0066@1|root,COG0066@2|Bacteria,46U20@74201|Verrucomicrobia,3K7RN@414999|Opitutae	414999|Opitutae	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
YHH3_k127_2770788_0	933262.AXAM01000098_gene3457	3.675e-102	345.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2MNJX@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YHH3_k127_2811305_0	595460.RRSWK_04038	4.317e-135	436.0	COG3119@1|root,COG5434@1|root,COG3119@2|Bacteria,COG5434@2|Bacteria,2IX9T@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF4976,Glyco_hydro_28,Pectate_lyase_3,Sulfatase
YHH3_k127_2811305_1	1268240.ATFI01000004_gene4401	2.938e-85	298.0	COG3119@1|root,COG3119@2|Bacteria,4NGX1@976|Bacteroidetes,2FMSX@200643|Bacteroidia,4AM4B@815|Bacteroidaceae	976|Bacteroidetes	P	COG COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_2829837_2	720555.BATR1942_10025	6.489e-53	192.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YHH3_k127_2829837_1	502025.Hoch_6093	1.041e-114	384.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales	28221|Deltaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
YHH3_k127_2829837_0	278957.ABEA03000180_gene2029	5.67e-142	477.0	COG1158@1|root,COG1158@2|Bacteria,46S5Y@74201|Verrucomicrobia,3K7JV@414999|Opitutae	414999|Opitutae	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
YHH3_k127_2829837_3	583355.Caka_1451	9.027e-38	150.0	COG0237@1|root,COG0237@2|Bacteria,46T2P@74201|Verrucomicrobia,3K83B@414999|Opitutae	414999|Opitutae	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
YHH3_k127_2829837_4	452637.Oter_3080	1.92e-32	135.0	2CIBN@1|root,2Z8JT@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
YHH3_k127_2840364_0	349741.Amuc_1305	1.576e-159	521.0	COG4590@1|root,COG4590@2|Bacteria	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YHH3_k127_2840364_1	1499967.BAYZ01000068_gene1919	4.135e-100	342.0	COG0581@1|root,COG0581@2|Bacteria,2NPJS@2323|unclassified Bacteria	2|Bacteria	P	phosphate transport system permease protein	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YHH3_k127_2843663_1	1121957.ATVL01000007_gene1530	3.723e-77	266.0	COG3250@1|root,COG3250@2|Bacteria,4NEWP@976|Bacteroidetes,47T9A@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Malectin
YHH3_k127_2843663_0	1288963.ADIS_1786	2.481e-155	512.0	COG3408@1|root,COG3408@2|Bacteria,4NGV6@976|Bacteroidetes,47MN4@768503|Cytophagia	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
YHH3_k127_2843663_2	266117.Rxyl_2988	5.296e-65	227.0	COG1995@1|root,COG1995@2|Bacteria,2GRPG@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
YHH3_k127_2850782_0	452637.Oter_4245	2.908e-34	144.0	2A4RK@1|root,30TD0@2|Bacteria,46YHS@74201|Verrucomicrobia,3K9M1@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2850782_1	748247.AZKH_4305	7.552e-06	55.0	COG2204@1|root,COG3437@1|root,COG2204@2|Bacteria,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HATPase_c,HisKA,Response_reg
YHH3_k127_2851250_3	401053.AciPR4_1715	6.145e-59	224.0	COG4225@1|root,COG4225@2|Bacteria,3Y33A@57723|Acidobacteria,2JHQH@204432|Acidobacteriia	204432|Acidobacteriia	E	Glycosyl hydrolase family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
YHH3_k127_2851250_2	497964.CfE428DRAFT_4021	1.402e-115	387.0	COG1600@1|root,COG1600@2|Bacteria,46SDV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
YHH3_k127_2851250_1	583355.Caka_2128	1.576e-118	398.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia,3K7B8@414999|Opitutae	414999|Opitutae	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
YHH3_k127_2851250_4	1349822.NSB1T_04930	3.133e-06	55.0	COG1030@1|root,COG1030@2|Bacteria,4NGGV@976|Bacteroidetes,2FP4N@200643|Bacteroidia,22X22@171551|Porphyromonadaceae	976|Bacteroidetes	O	serine protease	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,Peptidase_S49,SDH_sah
YHH3_k127_2851250_0	794903.OPIT5_08095	2.976e-135	437.0	COG4864@1|root,COG4864@2|Bacteria,46TWZ@74201|Verrucomicrobia,3K7TX@414999|Opitutae	414999|Opitutae	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
YHH3_k127_2854599_2	278957.ABEA03000167_gene2898	4.414e-25	115.0	COG3894@1|root,COG3894@2|Bacteria	2|Bacteria	C	2Fe-2S iron-sulfur cluster binding domain	nqrF	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
YHH3_k127_2854599_1	382464.ABSI01000010_gene3486	1.309e-53	198.0	COG0145@1|root,COG0145@2|Bacteria,46VJ0@74201|Verrucomicrobia	74201|Verrucomicrobia	EQ	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
YHH3_k127_2854599_0	1268240.ATFI01000004_gene4391	6.802e-60	225.0	2C5Z1@1|root,33ZHM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2855389_0	382464.ABSI01000016_gene739	3.229e-29	134.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_2856260_1	452637.Oter_1677	1.51e-149	485.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia,3K7ER@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH3_k127_2856260_3	583355.Caka_2020	1.775e-124	418.0	COG0815@1|root,COG0815@2|Bacteria,46SPW@74201|Verrucomicrobia,3K74H@414999|Opitutae	414999|Opitutae	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
YHH3_k127_2856260_4	1123279.ATUS01000001_gene1864	2.813e-80	271.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1J5T8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2818 3-methyladenine DNA glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
YHH3_k127_2856260_0	382464.ABSI01000002_gene4275	3.275e-150	506.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia,2IU0C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
YHH3_k127_2856260_2	278957.ABEA03000157_gene652	1.946e-136	464.0	COG1199@1|root,COG1199@2|Bacteria,46TTB@74201|Verrucomicrobia,3K7UT@414999|Opitutae	414999|Opitutae	KL	HELICc2	-	-	-	-	-	-	-	-	-	-	-	-	DEAD_2,Helicase_C_2
YHH3_k127_2856260_5	1123070.KB899258_gene1913	1.425e-33	140.0	2A42S@1|root,30SMP@2|Bacteria,46W5B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Nickel-containing superoxide dismutase	-	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
YHH3_k127_2865669_3	113355.CM001775_gene415	1.098e-10	68.0	COG3744@1|root,COG3744@2|Bacteria,1G7TY@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_2865669_2	472759.Nhal_2021	4.053e-14	77.0	2DPYJ@1|root,333YW@2|Bacteria,1NCVQ@1224|Proteobacteria,1SDCB@1236|Gammaproteobacteria,1X1KX@135613|Chromatiales	135613|Chromatiales	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH3_k127_2865669_0	713586.KB900536_gene1617	1.263e-176	572.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1WWF4@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH3_k127_2865669_1	583355.Caka_2025	6.602e-52	187.0	COG1704@1|root,COG1704@2|Bacteria,46V9M@74201|Verrucomicrobia,3K7DK@414999|Opitutae	414999|Opitutae	S	PFAM LemA family protein	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
YHH3_k127_2868017_3	794903.OPIT5_25205	4.835e-05	51.0	COG0854@1|root,COG0854@2|Bacteria,46SJT@74201|Verrucomicrobia,3K74Q@414999|Opitutae	414999|Opitutae	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
YHH3_k127_2868017_2	794903.OPIT5_17270	6.459e-53	198.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia,3K7VV@414999|Opitutae	414999|Opitutae	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH3_k127_2868017_0	583355.Caka_2701	1.403e-111	369.0	COG1039@1|root,COG1039@2|Bacteria,46UEQ@74201|Verrucomicrobia,3K72V@414999|Opitutae	414999|Opitutae	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH3_k127_2868017_1	583355.Caka_2691	8.861e-70	241.0	COG1194@1|root,COG1194@2|Bacteria,46SR4@74201|Verrucomicrobia,3K760@414999|Opitutae	414999|Opitutae	L	iron-sulfur cluster	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YHH3_k127_286820_2	794903.OPIT5_04420	4.15e-34	135.0	COG0346@1|root,COG0346@2|Bacteria,46VWN@74201|Verrucomicrobia,3K8EY@414999|Opitutae	414999|Opitutae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
YHH3_k127_286820_1	649638.Trad_1843	1.587e-77	274.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,PmoA
YHH3_k127_286820_0	1333507.AUTQ01000131_gene467	1.15e-122	413.0	COG0591@1|root,COG0591@2|Bacteria,1MW6E@1224|Proteobacteria,1RXYK@1236|Gammaproteobacteria,2Q5DK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_286820_3	1128912.GMES_0820	9.505e-09	67.0	28K4B@1|root,2Z9TA@2|Bacteria,1R47G@1224|Proteobacteria,1RRS5@1236|Gammaproteobacteria,466A9@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2956356_3	452637.Oter_2906	2.691e-08	66.0	2CC7E@1|root,32M7R@2|Bacteria,46UM2@74201|Verrucomicrobia,3K8H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2956356_4	649638.Trad_1839	2.179e-05	57.0	2CC7E@1|root,2Z7WG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2956356_0	926556.Echvi_2342	3.257e-159	512.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,47M6K@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YHH3_k127_2956356_2	452637.Oter_2906	4.43e-12	79.0	2CC7E@1|root,32M7R@2|Bacteria,46UM2@74201|Verrucomicrobia,3K8H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2956356_1	314230.DSM3645_14025	1.261e-70	252.0	COG3828@1|root,COG3828@2|Bacteria,2J0AZ@203682|Planctomycetes	203682|Planctomycetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
YHH3_k127_2956356_5	452637.Oter_1357	0.0006171	45.0	COG1609@1|root,COG1609@2|Bacteria,46UEV@74201|Verrucomicrobia,3K9DC@414999|Opitutae	2|Bacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
YHH3_k127_2975170_2	382464.ABSI01000011_gene2367	1.97e-68	241.0	COG3278@1|root,COG3278@2|Bacteria,46U5C@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	-
YHH3_k127_2975170_1	382464.ABSI01000011_gene2368	6.456e-82	280.0	COG1136@1|root,COG1136@2|Bacteria,46V8D@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
YHH3_k127_2975170_0	452637.Oter_0571	3.754e-130	425.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YHH3_k127_2975170_3	382464.ABSI01000011_gene2370	3.414e-56	207.0	COG0142@1|root,COG0142@2|Bacteria,46VHH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH3_k127_2975170_5	1122138.AQUZ01000017_gene6647	0.000741	49.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
YHH3_k127_2982468_0	794903.OPIT5_07890	8.776e-42	156.0	COG1694@1|root,COG1694@2|Bacteria,46W6C@74201|Verrucomicrobia,3K875@414999|Opitutae	414999|Opitutae	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
YHH3_k127_2982468_1	931626.Awo_c02450	1.306e-13	84.0	28QPF@1|root,2ZD50@2|Bacteria,1V2FS@1239|Firmicutes,24IPX@186801|Clostridia,25YK4@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3006616_0	583355.Caka_1356	3.103e-88	305.0	COG0564@1|root,COG0564@2|Bacteria,46W71@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the pseudouridine synthase RluA family	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
YHH3_k127_300917_2	1123054.KB907710_gene904	9.534e-77	264.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1WXQ0@135613|Chromatiales	135613|Chromatiales	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
YHH3_k127_300917_4	1049564.TevJSym_aj00120	9.824e-25	113.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,1S6AN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	phosphohydrolase	rela3	-	-	-	-	-	-	-	-	-	-	-	HD_4
YHH3_k127_300917_1	382464.ABSI01000010_gene3224	1.358e-96	333.0	COG1538@1|root,COG1538@2|Bacteria,46YW4@74201|Verrucomicrobia,2IU6N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_300917_0	1279015.KB908454_gene933	0.0	1146.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1Y4AF@135624|Aeromonadales	135624|Aeromonadales	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_300917_3	525897.Dbac_1916	1.893e-28	121.0	COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,42SQN@68525|delta/epsilon subdivisions,2WP8X@28221|Deltaproteobacteria,2MAGW@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K21137	-	M00821	-	-	ko00000,ko00002,ko02000	2.A.6.2.27,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH3_k127_3009497_0	1168034.FH5T_02405	1.895e-142	460.0	COG0673@1|root,COG0673@2|Bacteria,4NH13@976|Bacteroidetes,2FPIH@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_3048228_1	313606.M23134_02077	0.0006157	52.0	COG1404@1|root,COG2356@1|root,COG4677@1|root,COG1404@2|Bacteria,COG2356@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Calx-beta,LTD,fn3
YHH3_k127_3048228_0	1121101.HMPREF1532_01003	2.34e-93	319.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,2FM0P@200643|Bacteroidia,4AKYP@815|Bacteroidaceae	976|Bacteroidetes	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_3089299_1	1173023.KE650771_gene1057	0.0006879	45.0	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1JJNN@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
YHH3_k127_3089299_0	631362.Thi970DRAFT_00375	1.815e-169	541.0	COG0786@1|root,COG0786@2|Bacteria,1MVBC@1224|Proteobacteria,1RP0S@1236|Gammaproteobacteria,1WXWV@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the sodium-dependent transport of glutamate	-	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter
YHH3_k127_3132544_0	583355.Caka_2375	5.625e-50	186.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl,Hexapep
YHH3_k127_3132544_2	583355.Caka_1980	8.533e-46	174.0	2B9D7@1|root,322QY@2|Bacteria,46Y12@74201|Verrucomicrobia,3K9WH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3132544_1	1517416.IDAT_10965	5.734e-50	181.0	COG0454@1|root,COG0456@2|Bacteria,1RH71@1224|Proteobacteria,1S5XH@1236|Gammaproteobacteria,2QFZ8@267893|Idiomarinaceae	1236|Gammaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YHH3_k127_3141658_3	428125.CLOLEP_00574	9.133e-47	175.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,24AE7@186801|Clostridia,3WP52@541000|Ruminococcaceae	186801|Clostridia	M	Mandelate racemase muconate lactonizing enzyme, N-terminal domain	-	-	4.2.1.5,4.2.1.6	ko:K01683,ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YHH3_k127_3141658_2	794903.OPIT5_15415	6.539e-107	358.0	COG0673@1|root,COG0673@2|Bacteria,46SBW@74201|Verrucomicrobia,3K8TJ@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_3141658_1	595460.RRSWK_03705	1.172e-122	415.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	VVA1382	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_3141658_4	452637.Oter_1752	7.559e-13	69.0	COG1501@1|root,COG1501@2|Bacteria,46TKY@74201|Verrucomicrobia,3K9R3@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF5110,Glyco_hydro_31
YHH3_k127_3141658_0	452637.Oter_2315	1.696e-133	439.0	COG2211@1|root,COG2211@2|Bacteria,46UFW@74201|Verrucomicrobia	74201|Verrucomicrobia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
YHH3_k127_3182012_0	583355.Caka_2455	2.486e-158	509.0	COG1249@1|root,COG1249@2|Bacteria,46S7E@74201|Verrucomicrobia,3K76N@414999|Opitutae	414999|Opitutae	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH3_k127_3182012_2	290512.Paes_1180	5.664e-15	80.0	COG1950@1|root,COG1950@2|Bacteria,1FE4Y@1090|Chlorobi	1090|Chlorobi	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
YHH3_k127_3182012_1	382464.ABSI01000011_gene2494	1.014e-76	260.0	COG0129@1|root,COG0129@2|Bacteria,46SBY@74201|Verrucomicrobia,2ITPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	Dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
YHH3_k127_3197473_1	1121439.dsat_0668	1.939e-54	200.0	COG0642@1|root,COG3292@1|root,COG0642@2|Bacteria,COG3292@2|Bacteria,1NXDJ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07716,ko:K20974	ko02020,ko02025,ko04112,map02020,map02025,map04112	M00511,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,CHASE3,HATPase_c,HisKA,PAS_7,Response_reg
YHH3_k127_3197473_0	48698.ENSPFOP00000011765	4.231e-59	215.0	COG0434@1|root,2QUBS@2759|Eukaryota,38EZC@33154|Opisthokonta,3BES3@33208|Metazoa,3D0S4@33213|Bilateria,47ZQG@7711|Chordata,4905V@7742|Vertebrata,49RCN@7898|Actinopterygii	33208|Metazoa	S	Zgc 162297	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
YHH3_k127_3212758_0	382464.ABSI01000002_gene4374	3.128e-300	928.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH3_k127_3212758_1	382464.ABSI01000002_gene4373	7.967e-234	730.0	COG4656@1|root,COG4656@2|Bacteria,46W83@74201|Verrucomicrobia	74201|Verrucomicrobia	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
YHH3_k127_3264977_1	583355.Caka_0163	4.394e-68	239.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia,3K7UB@414999|Opitutae	414999|Opitutae	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
YHH3_k127_3264977_0	583355.Caka_0164	9.179e-115	378.0	COG0002@1|root,COG0002@2|Bacteria,46TRN@74201|Verrucomicrobia,3K8FU@414999|Opitutae	414999|Opitutae	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YHH3_k127_3273908_0	530564.Psta_1821	1.423e-321	996.0	COG3119@1|root,COG3119@2|Bacteria,2IX0Y@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YHH3_k127_3295318_0	583355.Caka_0671	1.048e-195	617.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,46UXA@74201|Verrucomicrobia,3K80M@414999|Opitutae	414999|Opitutae	P	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
YHH3_k127_3295318_1	1385515.N791_04060	1.854e-38	152.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RQM3@1236|Gammaproteobacteria,1X4AK@135614|Xanthomonadales	135614|Xanthomonadales	I	Cardiolipin synthase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
YHH3_k127_3303891_0	382464.ABSI01000010_gene3294	5.212e-87	309.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_3312270_1	583355.Caka_1112	4.435e-91	305.0	COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia,3K7QK@414999|Opitutae	414999|Opitutae	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YHH3_k127_3312270_0	314230.DSM3645_15810	9.34e-140	458.0	COG1448@1|root,COG1448@2|Bacteria,2IYDZ@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase	-	-	2.6.1.1	ko:K00813	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_3312270_2	278957.ABEA03000112_gene1382	5.498e-08	61.0	COG3137@1|root,COG3137@2|Bacteria,46TU0@74201|Verrucomicrobia,3K75A@414999|Opitutae	414999|Opitutae	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
YHH3_k127_3338465_2	452637.Oter_0897	5.378e-36	142.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,46S6T@74201|Verrucomicrobia,3K7S6@414999|Opitutae	414999|Opitutae	CO	Disulphide bond corrector protein DsbC	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YHH3_k127_3338465_0	420246.GTNG_0235	1.212e-49	183.0	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,1WECM@129337|Geobacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	ydaF	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
YHH3_k127_3338465_3	452637.Oter_0825	2.229e-19	96.0	2E78G@1|root,313PD@2|Bacteria,46WXY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF3016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3016
YHH3_k127_3338465_1	583355.Caka_2288	1.613e-39	160.0	COG1262@1|root,COG1262@2|Bacteria,46W2M@74201|Verrucomicrobia,3K81K@414999|Opitutae	414999|Opitutae	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
YHH3_k127_3339578_1	1121413.JMKT01000015_gene214	1.592e-23	101.0	COG1141@1|root,COG1141@2|Bacteria,1NIQZ@1224|Proteobacteria,42WTV@68525|delta/epsilon subdivisions,2WSPT@28221|Deltaproteobacteria,2MD3D@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
YHH3_k127_3339578_2	1283300.ATXB01000002_gene2951	4.855e-17	86.0	2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3339578_0	688269.Theth_0310	4.914e-48	179.0	COG1528@1|root,COG1528@2|Bacteria,2GD4M@200918|Thermotogae	200918|Thermotogae	P	Iron-storage protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
YHH3_k127_3347914_2	1232437.KL662000_gene4762	5.458e-06	52.0	COG2204@1|root,COG2204@2|Bacteria,1N2Q1@1224|Proteobacteria,42UAG@68525|delta/epsilon subdivisions,2WQU8@28221|Deltaproteobacteria,2MKH3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH3_k127_3347914_0	1232437.KL662000_gene4762	4.795e-70	244.0	COG2204@1|root,COG2204@2|Bacteria,1N2Q1@1224|Proteobacteria,42UAG@68525|delta/epsilon subdivisions,2WQU8@28221|Deltaproteobacteria,2MKH3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH3_k127_3347914_1	177437.HRM2_11810	1.114e-63	224.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P5K@68525|delta/epsilon subdivisions,2WMEF@28221|Deltaproteobacteria,2MJFC@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH3_k127_3365222_0	765420.OSCT_1615	7.514e-05	57.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi,375V5@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial Ig-like domain	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M_N,A2M_N_2,Big_5
YHH3_k127_3406192_3	203275.BFO_1768	4.605e-06	53.0	COG5316@1|root,COG5316@2|Bacteria,4NGER@976|Bacteroidetes,2G3FN@200643|Bacteroidia,22ZD5@171551|Porphyromonadaceae	976|Bacteroidetes	P	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140,Plug
YHH3_k127_3406192_0	794903.OPIT5_18985	8.705e-197	623.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
YHH3_k127_3430557_1	497964.CfE428DRAFT_6631	1.446e-37	158.0	COG3386@1|root,COG4733@1|root,COG3386@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K14274,ko:K20276	ko00040,ko02024,map00040,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	DUF5122,He_PIG,Laminin_G_3,SBBP,SGL,SLH
YHH3_k127_3430557_0	1403819.BATR01000066_gene1947	1.21e-56	201.0	COG1943@1|root,COG1943@2|Bacteria,46VP6@74201|Verrucomicrobia,2IVSQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH3_k127_3431354_0	583355.Caka_1188	0.0	1024.0	COG1643@1|root,COG1643@2|Bacteria,46TFT@74201|Verrucomicrobia,3K75C@414999|Opitutae	414999|Opitutae	L	Helicase associated domain (HA2)  Add an annotation	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
YHH3_k127_3438147_2	323848.Nmul_A0671	1.503e-09	59.0	COG3408@1|root,COG3408@2|Bacteria,1QUN2@1224|Proteobacteria,2WHH3@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
YHH3_k127_3438147_0	240016.ABIZ01000001_gene398	7.449e-226	713.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YHH3_k127_3438147_1	398767.Glov_1814	7.607e-13	68.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,43S1D@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
YHH3_k127_3438147_3	1297742.A176_03497	2.578e-06	49.0	COG3852@1|root,COG3852@2|Bacteria,1QVPN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,HisKA_7TM,PAS_4,PAS_8
YHH3_k127_348947_2	237368.SCABRO_00505	3.235e-58	207.0	COG2996@1|root,COG2996@2|Bacteria,2J1Y7@203682|Planctomycetes	203682|Planctomycetes	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
YHH3_k127_348947_0	1348583.ATLH01000016_gene3526	4.38e-67	230.0	COG1869@1|root,COG1869@2|Bacteria,4NMFR@976|Bacteroidetes,1I18A@117743|Flavobacteriia,1FA64@104264|Cellulophaga	976|Bacteroidetes	G	RbsD / FucU transport protein family	-	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
YHH3_k127_348947_3	452637.Oter_0976	1.16e-44	169.0	2ARE0@1|root,31GQ3@2|Bacteria,46WYB@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_348947_4	583355.Caka_0948	2.44e-41	158.0	2E6X2@1|root,331GI@2|Bacteria,46T38@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_348947_1	583355.Caka_0947	1.767e-65	231.0	2A104@1|root,30P5H@2|Bacteria,46YIA@74201|Verrucomicrobia,3K9N6@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
YHH3_k127_3602494_0	1537994.JQFW01000010_gene2804	1.43e-94	326.0	28I1E@1|root,2Z862@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
YHH3_k127_3606670_2	794903.OPIT5_03205	9.273e-99	328.0	COG0689@1|root,COG0689@2|Bacteria,46U55@74201|Verrucomicrobia,3K7EN@414999|Opitutae	414999|Opitutae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
YHH3_k127_3606670_3	631362.Thi970DRAFT_02627	4.118e-66	250.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,1T1YN@1236|Gammaproteobacteria,1X2SS@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,Response_reg,dCache_1
YHH3_k127_3606670_0	1367847.JCM7686_2578	4.129e-143	464.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,2PUW0@265|Paracoccus	28211|Alphaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5,6.2.1.9	ko:K01903,ko:K14067	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
YHH3_k127_3606670_1	404380.Gbem_1465	6.763e-123	400.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,43TQR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
YHH3_k127_3606670_5	518766.Rmar_1250	9.614e-22	98.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1FJIM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YHH3_k127_3606670_4	382464.ABSI01000012_gene1989	2.496e-36	145.0	COG1514@1|root,COG1514@2|Bacteria,46SZP@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
YHH3_k127_362223_2	794903.OPIT5_10425	2.492e-59	221.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529,ko:K03435,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
YHH3_k127_362223_0	382464.ABSI01000016_gene739	8.363e-137	481.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_362223_4	263358.VAB18032_09100	5.62e-05	57.0	COG2120@1|root,COG2120@2|Bacteria,2HVRX@201174|Actinobacteria,4DHQD@85008|Micromonosporales	201174|Actinobacteria	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,PIG-L
YHH3_k127_362223_1	485913.Krac_4375	1.37e-88	304.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH3_k127_362223_3	653045.Strvi_3618	9.76e-13	71.0	COG1082@1|root,COG1082@2|Bacteria,2IINM@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_3668959_1	290397.Adeh_2038	1.213e-36	147.0	2E01F@1|root,32VQP@2|Bacteria,1QW0U@1224|Proteobacteria,42TWT@68525|delta/epsilon subdivisions,2WQQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
YHH3_k127_3668959_0	382464.ABSI01000013_gene1747	7.601e-166	544.0	COG0488@1|root,COG0488@2|Bacteria,46V06@74201|Verrucomicrobia,2IU2D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YHH3_k127_3668959_2	583355.Caka_0950	2.389e-35	143.0	COG1102@1|root,COG1102@2|Bacteria,46YNS@74201|Verrucomicrobia,3K9W8@414999|Opitutae	414999|Opitutae	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
YHH3_k127_3697781_1	1198114.AciX9_2627	5.605e-45	167.0	COG4104@1|root,COG4104@2|Bacteria,3Y5VI@57723|Acidobacteria,2JNSN@204432|Acidobacteriia	204432|Acidobacteriia	S	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
YHH3_k127_3697781_0	497964.CfE428DRAFT_2851	1.402e-88	312.0	2F7XU@1|root,340BQ@2|Bacteria,46VS8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3698715_2	452637.Oter_3921	1.651e-55	198.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,46SG3@74201|Verrucomicrobia,3K7PG@414999|Opitutae	414999|Opitutae	IQ	AMP-dependent synthetase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
YHH3_k127_3698715_1	583355.Caka_2481	1.292e-63	227.0	COG0566@1|root,COG0566@2|Bacteria,46TF9@74201|Verrucomicrobia,3K7VA@414999|Opitutae	414999|Opitutae	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
YHH3_k127_3698715_0	349741.Amuc_0850	5.918e-135	441.0	COG2265@1|root,COG2265@2|Bacteria,46SYJ@74201|Verrucomicrobia,2ITST@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
YHH3_k127_3698715_3	583355.Caka_2430	2.953e-20	96.0	COG0095@1|root,COG0095@2|Bacteria,46VA1@74201|Verrucomicrobia,3K80G@414999|Opitutae	414999|Opitutae	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	-
YHH3_k127_3704390_5	794903.OPIT5_28865	1.012e-07	56.0	COG1235@1|root,COG1235@2|Bacteria,46SKU@74201|Verrucomicrobia,3K7X5@414999|Opitutae	414999|Opitutae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
YHH3_k127_3704390_1	583355.Caka_2212	2.053e-131	424.0	COG1469@1|root,COG1469@2|Bacteria,46URN@74201|Verrucomicrobia,3K79E@414999|Opitutae	414999|Opitutae	F	GTP cyclohydrolase	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
YHH3_k127_3704390_3	1123070.KB899265_gene1827	6.252e-63	221.0	COG0229@1|root,COG0229@2|Bacteria,46TM8@74201|Verrucomicrobia,2IUM0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	SelR domain	-	-	-	-	-	-	-	-	-	-	-	-	SelR
YHH3_k127_3704390_2	1121028.ARQE01000010_gene983	2.223e-106	350.0	COG4813@1|root,COG4813@2|Bacteria,1P43S@1224|Proteobacteria,2TUH4@28211|Alphaproteobacteria,2PJCX@255475|Aurantimonadaceae	28211|Alphaproteobacteria	G	Trehalose utilisation	thuA	-	-	-	-	-	-	-	-	-	-	-	ThuA
YHH3_k127_3704390_0	794903.OPIT5_19870	3.284e-209	668.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,46TH0@74201|Verrucomicrobia,3K7SP@414999|Opitutae	414999|Opitutae	L	Helix-hairpin-helix domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8
YHH3_k127_3704390_4	382464.ABSI01000005_gene1401	9.164e-30	121.0	COG0189@1|root,COG0586@1|root,COG0189@2|Bacteria,COG0586@2|Bacteria,46UXZ@74201|Verrucomicrobia	74201|Verrucomicrobia	HJ	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH3_k127_3708071_1	583355.Caka_1211	4.303e-32	135.0	COG1385@1|root,COG1385@2|Bacteria,46SZQ@74201|Verrucomicrobia,3K7Y0@414999|Opitutae	414999|Opitutae	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
YHH3_k127_3708071_0	278957.ABEA03000126_gene3724	5.427e-226	710.0	COG5016@1|root,COG5016@2|Bacteria,46TT6@74201|Verrucomicrobia,3K76D@414999|Opitutae	414999|Opitutae	C	Pyruvate carboxyltransferase	-	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
YHH3_k127_3708071_2	583355.Caka_1187	7.448e-10	61.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Guanylate_cyc,HAMP,Response_reg,dCache_1
YHH3_k127_3711620_1	497964.CfE428DRAFT_2857	1.756e-23	116.0	COG3523@1|root,COG3523@2|Bacteria,46VI0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ImcF-related N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ImcF-related_N
YHH3_k127_3711620_0	497964.CfE428DRAFT_2859	4.431e-28	133.0	28SQ5@1|root,2ZF09@2|Bacteria,46WN6@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3716420_8	682795.AciX8_1298	6.533e-37	145.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YHH3_k127_3716420_5	926559.JoomaDRAFT_2293	1.374e-125	417.0	COG5434@1|root,COG5434@2|Bacteria,4NG9X@976|Bacteroidetes,1I0TN@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
YHH3_k127_3716420_4	880073.Calab_0031	1.51e-139	453.0	COG2017@1|root,COG2017@2|Bacteria,2NQA5@2323|unclassified Bacteria	2|Bacteria	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
YHH3_k127_3716420_3	714943.Mucpa_6535	1.075e-155	502.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1IR5T@117747|Sphingobacteriia	976|Bacteroidetes	S	Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
YHH3_k127_3716420_7	929713.NIASO_20250	7.554e-72	250.0	COG4126@1|root,COG4126@2|Bacteria,4NHAM@976|Bacteroidetes,1IQAE@117747|Sphingobacteriia	976|Bacteroidetes	E	Asp Glu hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
YHH3_k127_3716420_6	471854.Dfer_2139	5.068e-123	409.0	COG3395@1|root,COG3395@2|Bacteria,4NFF9@976|Bacteroidetes,47N65@768503|Cytophagia	976|Bacteroidetes	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537
YHH3_k127_3716420_1	714943.Mucpa_6538	3.115e-170	546.0	COG1850@1|root,COG1850@2|Bacteria,4NFRC@976|Bacteroidetes,1IQT7@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the RuBisCO large chain family	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
YHH3_k127_3716420_0	485913.Krac_4635	1.186e-257	824.0	COG3408@1|root,COG3408@2|Bacteria,2G7KB@200795|Chloroflexi	200795|Chloroflexi	G	PFAM alpha-L-rhamnosidase	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YHH3_k127_3716420_10	1121904.ARBP01000005_gene4750	1.669e-08	64.0	2EN3D@1|root,33FRH@2|Bacteria,4NZ77@976|Bacteroidetes,47T85@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3716420_2	518766.Rmar_0690	6.405e-157	509.0	COG1457@1|root,COG1457@2|Bacteria,4NHHC@976|Bacteroidetes	976|Bacteroidetes	F	Belongs to the purine-cytosine permease (2.A.39) family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3716420_9	471854.Dfer_2133	1.431e-31	130.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,47M6F@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
YHH3_k127_3717286_0	583355.Caka_1343	3.65e-100	341.0	COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia,3K74C@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
YHH3_k127_3801059_2	794903.OPIT5_21385	3.151e-92	308.0	COG0334@1|root,COG0334@2|Bacteria,46S9K@74201|Verrucomicrobia,3K78F@414999|Opitutae	414999|Opitutae	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YHH3_k127_3801059_0	562743.JH976435_gene3120	7.097e-161	519.0	COG1282@1|root,COG1282@2|Bacteria,1TP6K@1239|Firmicutes,4HFBD@91061|Bacilli	91061|Bacilli	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
YHH3_k127_3801059_3	382464.ABSI01000014_gene1434	1.695e-30	122.0	COG3288@1|root,COG3288@2|Bacteria,46T7S@74201|Verrucomicrobia	74201|Verrucomicrobia	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
YHH3_k127_3801059_1	382464.ABSI01000014_gene1433	1.363e-151	488.0	COG3288@1|root,COG3288@2|Bacteria,46SFW@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
YHH3_k127_3810689_1	583355.Caka_1045	9.448e-57	205.0	COG0491@1|root,COG0491@2|Bacteria,46T2E@74201|Verrucomicrobia,3K7YR@414999|Opitutae	414999|Opitutae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH3_k127_3810689_0	382464.ABSI01000007_gene4110	7.539e-147	470.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia,2ITM8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
YHH3_k127_381357_0	1123020.AUIE01000006_gene4095	8.615e-07	63.0	COG4447@1|root,COG4447@2|Bacteria,1NEB9@1224|Proteobacteria	1224|Proteobacteria	UW	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3820031_1	335283.Neut_0604	2.293e-116	379.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VJXE@28216|Betaproteobacteria,37226@32003|Nitrosomonadales	28216|Betaproteobacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD,NYN,OST-HTH
YHH3_k127_3820031_0	485913.Krac_2996	1.958e-200	642.0	COG0667@1|root,COG0673@1|root,COG0667@2|Bacteria,COG0673@2|Bacteria,2G6AM@200795|Chloroflexi	200795|Chloroflexi	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_3829509_6	382464.ABSI01000010_gene3844	4.257e-24	101.0	COG0175@1|root,COG0175@2|Bacteria,46U3C@74201|Verrucomicrobia,2IWKE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EH	Phosphoadenosine phosphosulfate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
YHH3_k127_3829509_12	382464.ABSI01000010_gene3774	4.611e-05	49.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
YHH3_k127_3829509_0	382464.ABSI01000010_gene3779	4.969e-214	684.0	COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia,2ITPR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	-	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YHH3_k127_3829509_11	330214.NIDE3391	1.277e-06	56.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
YHH3_k127_3829509_3	452637.Oter_4016	1.702e-87	297.0	COG0236@1|root,COG0764@1|root,COG0236@2|Bacteria,COG0764@2|Bacteria,46XU4@74201|Verrucomicrobia,3K848@414999|Opitutae	414999|Opitutae	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
YHH3_k127_3829509_1	452637.Oter_4015	5.446e-139	453.0	COG0304@1|root,COG0304@2|Bacteria,46UQ4@74201|Verrucomicrobia,3K78C@414999|Opitutae	414999|Opitutae	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH3_k127_3829509_2	452637.Oter_4013	9.259e-115	381.0	COG0707@1|root,COG0707@2|Bacteria,46UKT@74201|Verrucomicrobia,3K85S@414999|Opitutae	414999|Opitutae	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C
YHH3_k127_3829509_5	794903.OPIT5_25370	9.432e-37	144.0	COG2165@1|root,COG2165@2|Bacteria,46W6A@74201|Verrucomicrobia,3K883@414999|Opitutae	414999|Opitutae	NU	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
YHH3_k127_3829509_9	583355.Caka_1636	8.185e-13	77.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	VP0657	-	-	ko:K02457,ko:K02672,ko:K08084,ko:K08085	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	GspH,N_methyl,PilS
YHH3_k127_3829509_7	583355.Caka_1637	4.311e-23	108.0	2FF2I@1|root,3470U@2|Bacteria,46W1E@74201|Verrucomicrobia,3K8ET@414999|Opitutae	414999|Opitutae	S	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
YHH3_k127_3829509_8	583355.Caka_1638	6.685e-23	107.0	COG4795@1|root,COG4795@2|Bacteria,46WEK@74201|Verrucomicrobia,3K851@414999|Opitutae	414999|Opitutae	U	General secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH3_k127_3829509_4	382464.ABSI01000020_gene173	6.208e-38	156.0	COG3156@1|root,COG3156@2|Bacteria,46VZT@74201|Verrucomicrobia,2IUG2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
YHH3_k127_3829509_10	794903.OPIT5_25395	1.991e-10	72.0	COG4972@1|root,COG4972@2|Bacteria,46WVK@74201|Verrucomicrobia,3K8A8@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3862886_6	452637.Oter_1787	1.207e-17	86.0	COG1929@1|root,COG1929@2|Bacteria,46TGW@74201|Verrucomicrobia,3K730@414999|Opitutae	414999|Opitutae	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
YHH3_k127_3862886_3	382464.ABSI01000006_gene946	2.312e-124	415.0	COG3540@1|root,COG3540@2|Bacteria,46VN0@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3862886_4	1396141.BATP01000029_gene2254	2.452e-80	274.0	COG1573@1|root,COG1573@2|Bacteria,46UE4@74201|Verrucomicrobia,2ITSY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	uracil-dna glycosylase	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH3_k127_3862886_2	583355.Caka_1731	3.319e-128	422.0	COG0772@1|root,COG0772@2|Bacteria,46SQT@74201|Verrucomicrobia,3K7H4@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
YHH3_k127_3862886_0	382464.ABSI01000012_gene1970	1.524e-216	687.0	COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia,2ITMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
YHH3_k127_3862886_5	767817.Desgi_4458	1.637e-37	152.0	COG0500@1|root,COG0500@2|Bacteria,1UTAX@1239|Firmicutes,2527A@186801|Clostridia	186801|Clostridia	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3862886_1	382464.ABSI01000011_gene2592	3.961e-198	627.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
YHH3_k127_387757_9	583355.Caka_2447	4.698e-14	74.0	COG1678@1|root,COG1678@2|Bacteria,46VUF@74201|Verrucomicrobia,3K7ZM@414999|Opitutae	414999|Opitutae	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
YHH3_k127_387757_7	1131269.AQVV01000044_gene1782	2.321e-30	125.0	COG2143@1|root,COG2143@2|Bacteria	2|Bacteria	O	COG2143 Thioredoxin-related protein	soxS	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	Thioredoxin_2,Thioredoxin_7
YHH3_k127_387757_6	452637.Oter_3185	5.102e-37	149.0	COG2885@1|root,COG2885@2|Bacteria,46T4D@74201|Verrucomicrobia,3K879@414999|Opitutae	414999|Opitutae	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
YHH3_k127_387757_2	583355.Caka_1453	8.01e-78	266.0	COG2197@1|root,COG2197@2|Bacteria,46T2B@74201|Verrucomicrobia,3K7X9@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_387757_1	382464.ABSI01000010_gene3428	1.482e-111	372.0	COG0536@1|root,COG0536@2|Bacteria,46SBS@74201|Verrucomicrobia,2ITSD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
YHH3_k127_387757_5	583355.Caka_1314	1.085e-38	160.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH3_k127_387757_4	583355.Caka_1313	1.426e-41	169.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YHH3_k127_387757_0	583355.Caka_1312	2.226e-240	756.0	COG2804@1|root,COG2804@2|Bacteria,46TEW@74201|Verrucomicrobia,3K94U@414999|Opitutae	414999|Opitutae	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
YHH3_k127_387757_3	591001.Acfer_1306	1.917e-77	276.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H2VD@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.10,6.3.2.13	ko:K01928,ko:K15792	ko00300,ko00550,map00300,map00550	-	R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH3_k127_3919462_6	395493.BegalDRAFT_1420	7.484e-19	100.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,Response_reg
YHH3_k127_3919462_5	583355.Caka_1419	1.568e-27	115.0	COG0799@1|root,COG0799@2|Bacteria,46WCF@74201|Verrucomicrobia,3K89X@414999|Opitutae	414999|Opitutae	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
YHH3_k127_3919462_3	1234664.AMRO01000027_gene1397	1.189e-39	154.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,1WE1E@129337|Geobacillus	91061|Bacilli	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YHH3_k127_3919462_0	583355.Caka_1618	7.521e-220	707.0	COG1523@1|root,COG1523@2|Bacteria,46UHI@74201|Verrucomicrobia,3K7P7@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
YHH3_k127_3919462_1	349741.Amuc_0644	1.192e-112	375.0	COG0482@1|root,COG0482@2|Bacteria,46SQW@74201|Verrucomicrobia,2ITRY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
YHH3_k127_3919462_4	1396141.BATP01000035_gene4040	2.243e-32	133.0	COG0250@1|root,COG0250@2|Bacteria,46ZE1@74201|Verrucomicrobia,2IV04@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
YHH3_k127_3919462_2	794903.OPIT5_23520	2.759e-80	285.0	COG0265@1|root,COG0265@2|Bacteria,46YTI@74201|Verrucomicrobia,3K7TT@414999|Opitutae	414999|Opitutae	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2
YHH3_k127_392087_2	1396858.Q666_14305	6.179e-54	199.0	COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,1S3RA@1236|Gammaproteobacteria,466Y0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	FlgJ-related protein	bax	-	-	ko:K03796	-	-	-	-	ko00000	-	GH73	-	Glucosaminidase
YHH3_k127_392087_0	998674.ATTE01000001_gene3940	6.178e-95	322.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,460DW@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
YHH3_k127_392087_1	1192034.CAP_7877	6.346e-61	219.0	COG4559@1|root,COG4559@2|Bacteria,1RD7N@1224|Proteobacteria,43BZU@68525|delta/epsilon subdivisions,2X7AK@28221|Deltaproteobacteria,2Z04C@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system	hmuV	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
YHH3_k127_392087_3	864702.OsccyDRAFT_1574	9.947e-17	81.0	COG1169@1|root,COG1169@2|Bacteria,1G2H4@1117|Cyanobacteria,1H8AT@1150|Oscillatoriales	1117|Cyanobacteria	HQ	PFAM chorismate binding enzyme	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
YHH3_k127_3933176_1	382464.ABSI01000010_gene3492	0.000218	54.0	2DBYV@1|root,2ZBXC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3933176_0	497964.CfE428DRAFT_3578	1.977e-65	237.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YHH3_k127_39621_0	382464.ABSI01000005_gene1253	3.556e-81	276.0	COG0524@1|root,COG0524@2|Bacteria,46TT7@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH3_k127_39621_2	452637.Oter_3327	1.744e-77	264.0	COG0125@1|root,COG0125@2|Bacteria,46ST1@74201|Verrucomicrobia,3K7VY@414999|Opitutae	414999|Opitutae	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
YHH3_k127_39621_1	583355.Caka_2760	6.096e-78	271.0	COG0470@1|root,COG0470@2|Bacteria,46T6T@74201|Verrucomicrobia,3K7VJ@414999|Opitutae	414999|Opitutae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
YHH3_k127_39621_3	382464.ABSI01000014_gene1484	5.082e-27	113.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,2IUGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347,HlyD_D23
YHH3_k127_4010373_1	317936.Nos7107_3275	2.68e-91	302.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1HTXC@1161|Nostocales	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
YHH3_k127_4010373_0	479434.Sthe_1319	1.072e-199	632.0	COG1866@1|root,COG1866@2|Bacteria,2G5TD@200795|Chloroflexi,27YZT@189775|Thermomicrobia	189775|Thermomicrobia	H	Phosphoenolpyruvate carboxykinase	-	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
YHH3_k127_402901_0	1396141.BATP01000007_gene5639	5.695e-270	884.0	COG3209@1|root,COG3209@2|Bacteria,46XP0@74201|Verrucomicrobia,2IWA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_402901_1	1396141.BATP01000036_gene3830	4.755e-41	156.0	COG3558@1|root,COG3558@2|Bacteria,46V3F@74201|Verrucomicrobia,2IWQU@203494|Verrucomicrobiae	2|Bacteria	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
YHH3_k127_4032259_4	583355.Caka_0677	2.358e-120	398.0	COG1167@1|root,COG1167@2|Bacteria,46TGY@74201|Verrucomicrobia,3K7IS@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YHH3_k127_4032259_8	583355.Caka_2036	2.51e-51	186.0	2F9J5@1|root,341VF@2|Bacteria,46VQB@74201|Verrucomicrobia,3K7XZ@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
YHH3_k127_4032259_0	583355.Caka_1712	5.343e-237	745.0	COG1132@1|root,COG1132@2|Bacteria,46YXP@74201|Verrucomicrobia,3K7FZ@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH3_k127_4032259_2	1121439.dsat_2827	1.197e-164	538.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2WJY9@28221|Deltaproteobacteria,2M8FD@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	SMART Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
YHH3_k127_4032259_1	583355.Caka_1486	2.304e-193	620.0	COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,3K7RX@414999|Opitutae	414999|Opitutae	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
YHH3_k127_4032259_3	640510.BC1001_1288	2.547e-148	482.0	COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,2VP16@28216|Betaproteobacteria,1K0AZ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)	astB	-	3.5.3.23	ko:K01484	ko00330,ko01100,map00330,map01100	-	R04189	RC00024	ko00000,ko00001,ko01000	-	-	-	AstB
YHH3_k127_4032259_6	686340.Metal_2200	2.35e-74	267.0	2C6BE@1|root,32XBJ@2|Bacteria,1NB89@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4032259_7	1449049.JONW01000013_gene4728	5.676e-53	205.0	COG0729@1|root,COG0729@2|Bacteria,1PFDU@1224|Proteobacteria	1224|Proteobacteria	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
YHH3_k127_4032259_5	1396141.BATP01000020_gene17	2.651e-104	346.0	COG4313@1|root,COG4313@2|Bacteria,46UHV@74201|Verrucomicrobia,2IVEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YHH3_k127_4108197_2	382464.ABSI01000011_gene2680	1.937e-08	55.0	COG1305@1|root,COG1305@2|Bacteria,46SMU@74201|Verrucomicrobia,2IU95@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
YHH3_k127_4108197_1	314230.DSM3645_12971	5.268e-68	248.0	COG1609@1|root,COG2207@1|root,COG1609@2|Bacteria,COG2207@2|Bacteria,2IXTX@203682|Planctomycetes	203682|Planctomycetes	K	Xylose operon regulatory protein	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Peripla_BP_3
YHH3_k127_4108197_0	1279017.AQYJ01000026_gene259	4.81e-68	245.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179,ko:K03932	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	CE1,GH5,GH9	-	CBM_2,CBM_4_9,Cellulase,Glyco_hydro_16,PSCyt3,PSD3,PSD4,PSD5,RicinB_lectin_2,YceI
YHH3_k127_4141798_3	278957.ABEA03000166_gene4026	1.17e-93	319.0	COG0407@1|root,COG0407@2|Bacteria	278957.ABEA03000166_gene4026|-	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4141798_0	998674.ATTE01000001_gene3304	6.307e-157	503.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATPase, AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_4141798_1	555779.Dthio_PD3715	1.045e-147	477.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42MFI@68525|delta/epsilon subdivisions,2WKXD@28221|Deltaproteobacteria,2MAH6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_4141798_2	589865.DaAHT2_1405	2.287e-124	409.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42MFI@68525|delta/epsilon subdivisions,2WKXD@28221|Deltaproteobacteria,2MM6V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_4183469_1	382464.ABSI01000013_gene1703	4.085e-300	938.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,46TG1@74201|Verrucomicrobia,2ITWA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
YHH3_k127_4183469_0	452637.Oter_0843	0.0	1316.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,46UHB@74201|Verrucomicrobia,3K7CZ@414999|Opitutae	2|Bacteria	C	PFAM FAD linked oxidase domain protein	MA20_43170	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
YHH3_k127_4183469_2	338963.Pcar_0306	1.564e-73	279.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42PH4@68525|delta/epsilon subdivisions,2WME5@28221|Deltaproteobacteria,43T1N@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Conserved TM helix	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
YHH3_k127_4214911_3	1500893.JQNB01000001_gene1119	4.876e-11	73.0	COG3240@1|root,COG5571@1|root,COG3240@2|Bacteria,COG5571@2|Bacteria,1MWDI@1224|Proteobacteria,1S2RQ@1236|Gammaproteobacteria,1X3QI@135614|Xanthomonadales	135614|Xanthomonadales	IN	esterase	estA	-	-	ko:K12686	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.8	-	-	Autotransporter,Lipase_GDSL
YHH3_k127_4214911_2	338969.Rfer_2331	5.045e-14	77.0	COG3240@1|root,COG3240@2|Bacteria,1MWDI@1224|Proteobacteria,2VTBY@28216|Betaproteobacteria	28216|Betaproteobacteria	I	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
YHH3_k127_4214911_0	454957.IA64_17745	1.422e-70	252.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,1RMAR@1236|Gammaproteobacteria,1X4DE@135614|Xanthomonadales	135614|Xanthomonadales	P	ABC-type sulfate transport system, periplasmic component	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
YHH3_k127_4235607_0	583355.Caka_3033	4.175e-167	536.0	COG1331@1|root,COG1331@2|Bacteria,46SEJ@74201|Verrucomicrobia,3K76Y@414999|Opitutae	414999|Opitutae	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
YHH3_k127_4256158_1	1442599.JAAN01000020_gene2520	4.791e-93	317.0	COG2273@1|root,COG2273@2|Bacteria,1N5RS@1224|Proteobacteria,1RSMD@1236|Gammaproteobacteria,1X5MJ@135614|Xanthomonadales	135614|Xanthomonadales	G	Glycosyl hydrolases family 16	lamA	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
YHH3_k127_4256158_0	388739.RSK20926_07407	3.358e-98	327.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TRRN@28211|Alphaproteobacteria,2P4CU@2433|Roseobacter	28211|Alphaproteobacteria	F	Metal binding domain of Ada	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
YHH3_k127_4269819_1	583355.Caka_0005	6.256e-86	293.0	COG0500@1|root,COG2226@2|Bacteria,46STX@74201|Verrucomicrobia,3K7U4@414999|Opitutae	414999|Opitutae	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
YHH3_k127_4269819_0	794903.OPIT5_27530	5.933e-181	578.0	COG1219@1|root,COG1219@2|Bacteria,46U7E@74201|Verrucomicrobia,3K7VN@414999|Opitutae	414999|Opitutae	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
YHH3_k127_433135_7	278957.ABEA03000051_gene210	4.184e-23	108.0	COG0771@1|root,COG0771@2|Bacteria,46UT1@74201|Verrucomicrobia,3K78H@414999|Opitutae	414999|Opitutae	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
YHH3_k127_433135_5	278957.ABEA03000051_gene211	5.149e-29	130.0	COG1388@1|root,COG1388@2|Bacteria,46T90@74201|Verrucomicrobia,3K8BU@414999|Opitutae	414999|Opitutae	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
YHH3_k127_433135_0	583355.Caka_3071	2.394e-110	368.0	COG0772@1|root,COG0772@2|Bacteria,46SMC@74201|Verrucomicrobia,3K7ID@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
YHH3_k127_433135_3	452637.Oter_2636	5.353e-81	283.0	COG0707@1|root,COG0707@2|Bacteria,46UBI@74201|Verrucomicrobia,3KA2U@414999|Opitutae	414999|Opitutae	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
YHH3_k127_433135_4	382464.ABSI01000002_gene4363	1.71e-65	235.0	COG1181@1|root,COG1181@2|Bacteria,46UZ2@74201|Verrucomicrobia,2IU29@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
YHH3_k127_433135_6	452637.Oter_2639	4.758e-24	114.0	COG1589@1|root,COG1589@2|Bacteria,46T4T@74201|Verrucomicrobia,3K847@414999|Opitutae	414999|Opitutae	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	POTRA_1
YHH3_k127_433135_2	583355.Caka_3076	1.401e-100	341.0	COG0849@1|root,COG0849@2|Bacteria,46SQI@74201|Verrucomicrobia,3K782@414999|Opitutae	414999|Opitutae	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
YHH3_k127_433135_1	452637.Oter_2641	6.124e-101	342.0	COG0206@1|root,COG0206@2|Bacteria,46UAJ@74201|Verrucomicrobia,3K7KG@414999|Opitutae	414999|Opitutae	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YHH3_k127_4334135_1	583355.Caka_1541	8.31e-62	220.0	COG0215@1|root,COG0215@2|Bacteria,46SES@74201|Verrucomicrobia,3K7N2@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
YHH3_k127_4334135_0	583355.Caka_1540	1.814e-134	435.0	COG0113@1|root,COG0113@2|Bacteria,46S91@74201|Verrucomicrobia,3K7HG@414999|Opitutae	414999|Opitutae	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
YHH3_k127_4344296_1	1396418.BATQ01000017_gene4164	5.111e-13	80.0	COG4625@1|root,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,Laminin_G_3
YHH3_k127_4344296_0	1122222.AXWR01000015_gene1159	1.541e-95	321.0	COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
YHH3_k127_4355025_3	382464.ABSI01000011_gene2741	1.242e-163	528.0	28HY3@1|root,2Z83I@2|Bacteria	2|Bacteria	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
YHH3_k127_4355025_8	1183438.GKIL_2549	3.308e-100	338.0	COG2957@1|root,COG2957@2|Bacteria,1G1FA@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
YHH3_k127_4355025_6	1121920.AUAU01000036_gene1118	1.289e-113	375.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
YHH3_k127_4355025_10	941449.dsx2_0721	6.318e-19	90.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WRRT@28221|Deltaproteobacteria,2MCID@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH3_k127_4355025_0	583355.Caka_1919	0.0	2195.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia,3K79V@414999|Opitutae	414999|Opitutae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH3_k127_4355025_1	452637.Oter_2998	4.555e-279	881.0	COG0550@1|root,COG0550@2|Bacteria,46S97@74201|Verrucomicrobia,3K7FV@414999|Opitutae	414999|Opitutae	L	DNA topoisomerase type IA central domain protein	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
YHH3_k127_4355025_4	452637.Oter_3000	2.649e-153	491.0	COG0075@1|root,COG0075@2|Bacteria,46SCI@74201|Verrucomicrobia,3K7QY@414999|Opitutae	414999|Opitutae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YHH3_k127_4355025_2	583355.Caka_1758	2.177e-227	715.0	COG1233@1|root,COG1233@2|Bacteria,46YTW@74201|Verrucomicrobia,3K7V6@414999|Opitutae	414999|Opitutae	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
YHH3_k127_4355025_9	583355.Caka_1903	3.52e-53	191.0	COG0764@1|root,COG0764@2|Bacteria,46VX8@74201|Verrucomicrobia,3K8BA@414999|Opitutae	414999|Opitutae	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
YHH3_k127_4355025_7	583355.Caka_1902	3.891e-101	336.0	COG0623@1|root,COG0623@2|Bacteria,46TU1@74201|Verrucomicrobia,3K780@414999|Opitutae	414999|Opitutae	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YHH3_k127_4355025_5	583355.Caka_1901	1.86e-119	392.0	COG0332@1|root,COG0332@2|Bacteria,46UBS@74201|Verrucomicrobia,3K7QN@414999|Opitutae	414999|Opitutae	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	-	ko:K22317	-	-	-	-	ko00000	-	-	-	ACP_syn_III,ACP_syn_III_C
YHH3_k127_4389085_2	237368.SCABRO_01922	4.664e-12	72.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	Thioredoxin_7
YHH3_k127_4389085_0	65393.PCC7424_1191	3.819e-83	293.0	COG0683@1|root,COG0683@2|Bacteria,1GBP3@1117|Cyanobacteria	1117|Cyanobacteria	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4389085_1	583355.Caka_1054	1.835e-57	205.0	COG2262@1|root,COG2262@2|Bacteria,46SP4@74201|Verrucomicrobia,3K7S8@414999|Opitutae	414999|Opitutae	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YHH3_k127_4390015_0	1353537.TP2_00585	7.78e-166	541.0	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG4625@1|root,COG4935@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria,COG4935@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,DUF4214,HemolysinCabind,Hint_2
YHH3_k127_4398213_2	583355.Caka_2021	2.612e-43	162.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia,3K7ER@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH3_k127_4398213_1	278957.ABEA03000191_gene1025	1.257e-152	490.0	COG0343@1|root,COG0343@2|Bacteria,46TZR@74201|Verrucomicrobia,3K78J@414999|Opitutae	414999|Opitutae	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
YHH3_k127_4398213_0	765912.Thimo_0495	2.456e-208	659.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1WW84@135613|Chromatiales	135613|Chromatiales	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
YHH3_k127_4455525_0	1123228.AUIH01000023_gene3133	2.36e-106	361.0	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,1XMG0@135619|Oceanospirillales	135619|Oceanospirillales	K	ATP-dependent transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
YHH3_k127_4455525_1	1125973.JNLC01000005_gene4168	8.188e-15	78.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,3JWIG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
YHH3_k127_4457759_0	583355.Caka_1947	7.491e-62	219.0	COG0604@1|root,COG0604@2|Bacteria,46VV3@74201|Verrucomicrobia,3K9E2@414999|Opitutae	414999|Opitutae	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_4457759_1	452637.Oter_3506	9.746e-43	170.0	COG0553@1|root,COG0553@2|Bacteria,46TSJ@74201|Verrucomicrobia,3K74S@414999|Opitutae	414999|Opitutae	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH3_k127_4500023_4	1120936.KB907210_gene5715	1.545e-10	68.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4EHNS@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YHH3_k127_4500023_2	452637.Oter_4603	5.089e-104	364.0	COG1305@1|root,COG1305@2|Bacteria,46T2X@74201|Verrucomicrobia,3K7KB@414999|Opitutae	414999|Opitutae	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,Transglut_core
YHH3_k127_4500023_0	583355.Caka_1965	3.588e-179	580.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,3K7FW@414999|Opitutae	414999|Opitutae	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
YHH3_k127_4500023_3	583355.Caka_1963	1.067e-74	260.0	COG1792@1|root,COG1792@2|Bacteria,46T2J@74201|Verrucomicrobia,3K7Q6@414999|Opitutae	414999|Opitutae	M	shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
YHH3_k127_4500023_1	278957.ABEA03000085_gene2576	2.14e-108	354.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,3K759@414999|Opitutae	414999|Opitutae	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH3_k127_4513266_1	177437.HRM2_30830	6.59e-31	125.0	COG0169@1|root,COG0169@2|Bacteria	2|Bacteria	E	shikimate 3-dehydrogenase (NADP+) activity	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
YHH3_k127_4513266_0	1121405.dsmv_0505	2.756e-168	540.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42QJF@68525|delta/epsilon subdivisions,2WJ9D@28221|Deltaproteobacteria,2MIGZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
YHH3_k127_4519236_0	768671.ThimaDRAFT_0775	3.801e-178	562.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,1RMGK@1236|Gammaproteobacteria,1WWHA@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH3_k127_4519236_2	382464.ABSI01000013_gene1628	4.903e-24	106.0	COG0571@1|root,COG0571@2|Bacteria,46WCW@74201|Verrucomicrobia,2IUR4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ribonuclease III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4519236_1	794903.OPIT5_17990	1.864e-130	424.0	COG0265@1|root,COG0265@2|Bacteria,46X1C@74201|Verrucomicrobia,3K7EQ@414999|Opitutae	414999|Opitutae	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH3_k127_4580085_2	1341155.FSS13T_21560	5.037e-12	70.0	COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH3_k127_4580085_0	994573.T472_0201480	4.498e-205	649.0	COG2211@1|root,COG2211@2|Bacteria,1TSEH@1239|Firmicutes,248PV@186801|Clostridia,36QC3@31979|Clostridiaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
YHH3_k127_4580085_1	349521.HCH_03632	1.084e-120	397.0	COG0730@1|root,COG0730@2|Bacteria,1QRFH@1224|Proteobacteria,1RRFY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
YHH3_k127_4623865_0	583355.Caka_2169	4.837e-165	535.0	COG2203@1|root,COG3605@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG4191@2|Bacteria,46SAZ@74201|Verrucomicrobia,3K7H5@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
YHH3_k127_4623865_1	583355.Caka_2316	1.086e-62	223.0	COG1403@1|root,COG1403@2|Bacteria,46SMP@74201|Verrucomicrobia,3K7K4@414999|Opitutae	414999|Opitutae	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
YHH3_k127_4623865_2	278957.ABEA03000153_gene3519	7.021e-31	129.0	COG0469@1|root,COG0469@2|Bacteria,46SBJ@74201|Verrucomicrobia,3K7C0@414999|Opitutae	414999|Opitutae	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
YHH3_k127_4712045_0	1198452.Jab_2c21390	8.016e-11	66.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria	28216|Betaproteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Haemagg_act
YHH3_k127_4712045_1	1472716.KBK24_0120540	1.096e-08	68.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,2VJXF@28216|Betaproteobacteria,1K3E2@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Polypeptide-transport-associated domain protein ShlB-type	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
YHH3_k127_4762110_0	994573.T472_0201480	8.873e-204	644.0	COG2211@1|root,COG2211@2|Bacteria,1TSEH@1239|Firmicutes,248PV@186801|Clostridia,36QC3@31979|Clostridiaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
YHH3_k127_4762110_1	1380380.JIAX01000006_gene933	5.658e-73	256.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,2TSNZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Ion transport protein	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
YHH3_k127_477131_1	1266909.AUAG01000023_gene62	2.719e-115	384.0	COG3177@1|root,COG3177@2|Bacteria,1MVW0@1224|Proteobacteria,1RYFI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH3_k127_477131_0	1123392.AQWL01000003_gene459	1.351e-158	503.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
YHH3_k127_4804494_0	452637.Oter_3022	2.014e-110	366.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,46U8V@74201|Verrucomicrobia,3K7U6@414999|Opitutae	414999|Opitutae	E	Prephenate dehydratase	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
YHH3_k127_4804494_1	583355.Caka_2329	5.615e-74	259.0	COG1386@1|root,COG1386@2|Bacteria,46V9G@74201|Verrucomicrobia,3K7RR@414999|Opitutae	414999|Opitutae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
YHH3_k127_4810694_14	382464.ABSI01000013_gene1772	4.963e-17	89.0	299RH@1|root,2ZWTR@2|Bacteria,46WTD@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4810694_7	382464.ABSI01000013_gene1810	3.046e-91	314.0	COG1594@1|root,COG1594@2|Bacteria,46XN4@74201|Verrucomicrobia,2IW8B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4810694_2	583355.Caka_0673	3.463e-173	555.0	COG1249@1|root,COG1249@2|Bacteria,46S8I@74201|Verrucomicrobia,3K7TS@414999|Opitutae	414999|Opitutae	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
YHH3_k127_4810694_1	452637.Oter_3521	1.702e-182	587.0	COG1052@1|root,COG1052@2|Bacteria,46SAN@74201|Verrucomicrobia,3K77J@414999|Opitutae	414999|Opitutae	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH3_k127_4810694_8	452637.Oter_3520	1.024e-47	178.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,3K83M@414999|Opitutae	414999|Opitutae	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
YHH3_k127_4810694_4	794903.OPIT5_19750	1.955e-142	472.0	COG0460@1|root,COG0460@2|Bacteria,46TFC@74201|Verrucomicrobia,3K7MC@414999|Opitutae	414999|Opitutae	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
YHH3_k127_4810694_3	583355.Caka_2605	2.005e-172	550.0	COG0527@1|root,COG0527@2|Bacteria,46TWW@74201|Verrucomicrobia,3K7MP@414999|Opitutae	414999|Opitutae	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
YHH3_k127_4810694_0	452637.Oter_3518	3.908e-190	602.0	COG0498@1|root,COG0498@2|Bacteria,46TPG@74201|Verrucomicrobia,3K7E5@414999|Opitutae	414999|Opitutae	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
YHH3_k127_4810694_6	583355.Caka_2245	4.932e-112	370.0	COG0240@1|root,COG0240@2|Bacteria,46UHW@74201|Verrucomicrobia,3K7IP@414999|Opitutae	414999|Opitutae	I	glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
YHH3_k127_4810694_11	583355.Caka_1391	1.255e-32	132.0	COG4970@1|root,COG4970@2|Bacteria,46YP2@74201|Verrucomicrobia,3K9X0@414999|Opitutae	414999|Opitutae	NU	Tfp pilus assembly protein FimT	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	-
YHH3_k127_4810694_5	583355.Caka_1193	2.131e-118	394.0	COG0477@1|root,COG2814@2|Bacteria,46U1F@74201|Verrucomicrobia,3K73V@414999|Opitutae	414999|Opitutae	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YHH3_k127_4810694_9	583355.Caka_1192	1.428e-46	173.0	COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia,3K81B@414999|Opitutae	414999|Opitutae	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YHH3_k127_4810694_12	382464.ABSI01000010_gene3305	2.423e-29	125.0	COG0558@1|root,COG0558@2|Bacteria,46VZY@74201|Verrucomicrobia,2IUG1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YHH3_k127_4810694_10	452637.Oter_3640	5.152e-35	140.0	COG1267@1|root,COG1267@2|Bacteria,46VNU@74201|Verrucomicrobia,3K86I@414999|Opitutae	414999|Opitutae	I	Phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
YHH3_k127_4830967_6	382464.ABSI01000011_gene2642	2.396e-26	112.0	COG0079@1|root,COG0079@2|Bacteria,46SFP@74201|Verrucomicrobia,2ITIN@203494|Verrucomicrobiae	2|Bacteria	E	Aminotransferase class I and II	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iJN678.hisC	Aminotran_1_2
YHH3_k127_4830967_2	583355.Caka_2357	1.94e-141	463.0	COG0141@1|root,COG0141@2|Bacteria,46SHG@74201|Verrucomicrobia,3K7N3@414999|Opitutae	414999|Opitutae	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
YHH3_k127_4830967_0	452637.Oter_0192	6.376e-240	750.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	414999|Opitutae	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
YHH3_k127_4830967_7	278957.ABEA03000152_gene4081	4.552e-11	66.0	29TM9@1|root,30EUT@2|Bacteria,46XC0@74201|Verrucomicrobia,3K8GF@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_4830967_5	382464.ABSI01000011_gene2646	5.243e-46	172.0	COG0203@1|root,COG0203@2|Bacteria,46TC9@74201|Verrucomicrobia,2IUE5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
YHH3_k127_4830967_1	583355.Caka_1665	7.755e-161	511.0	COG0202@1|root,COG0202@2|Bacteria,46S52@74201|Verrucomicrobia,3K7N7@414999|Opitutae	414999|Opitutae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YHH3_k127_4830967_3	583355.Caka_1666	2.152e-88	295.0	COG0522@1|root,COG0522@2|Bacteria,46SNI@74201|Verrucomicrobia,3K7K0@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
YHH3_k127_4830967_4	583355.Caka_1667	4.359e-62	218.0	COG0100@1|root,COG0100@2|Bacteria,46STW@74201|Verrucomicrobia,3K82X@414999|Opitutae	414999|Opitutae	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YHH3_k127_4840666_1	278957.ABEA03000041_gene2247	7.509e-63	220.0	COG0331@1|root,COG0331@2|Bacteria,46TH5@74201|Verrucomicrobia,3K7U9@414999|Opitutae	414999|Opitutae	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
YHH3_k127_4840666_0	583355.Caka_0762	9.065e-238	742.0	COG0481@1|root,COG0481@2|Bacteria,46SA7@74201|Verrucomicrobia,3K7NB@414999|Opitutae	414999|Opitutae	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YHH3_k127_488753_2	1173264.KI913949_gene3535	1.276e-21	97.0	COG0318@1|root,COG0318@2|Bacteria,1G2RA@1117|Cyanobacteria,1H7H7@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.menE	AMP-binding,AMP-binding_C
YHH3_k127_488753_0	497964.CfE428DRAFT_0727	1.079e-211	671.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,46UC6@74201|Verrucomicrobia	74201|Verrucomicrobia	C	IMP dehydrogenase GMP reductase	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
YHH3_k127_488753_1	452637.Oter_3652	1.635e-126	411.0	COG0761@1|root,COG0761@2|Bacteria,46SYM@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
YHH3_k127_4952189_3	880073.Calab_2883	9.363e-19	87.0	COG0493@1|root,COG0493@2|Bacteria,2NNUI@2323|unclassified Bacteria	2|Bacteria	E	Flavin containing amine oxidoreductase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450	Fer4_20,Pyr_redox_2
YHH3_k127_4952189_0	583355.Caka_1869	0.0	1926.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,46U9T@74201|Verrucomicrobia,3K7GP@414999|Opitutae	414999|Opitutae	E	glutamate synthase	-	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
YHH3_k127_4952189_1	649349.Lbys_2037	1.875e-26	119.0	COG2935@1|root,COG2935@2|Bacteria,4P1RD@976|Bacteroidetes,47U44@768503|Cytophagia	976|Bacteroidetes	O	PFAM Arginine-tRNA-protein transferase, C terminus	-	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	Acetyltransf_6
YHH3_k127_4952189_2	246195.DNO_0986	1.312e-21	96.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iWFL_1372.ECW_m0084,ic_1306.c0103	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH3_k127_5025332_4	382464.ABSI01000011_gene2729	8.417e-67	232.0	COG0014@1|root,COG0014@2|Bacteria,46SGA@74201|Verrucomicrobia,2ITYN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH3_k127_5025332_1	583355.Caka_2116	4.834e-102	345.0	COG0157@1|root,COG0157@2|Bacteria,46UE1@74201|Verrucomicrobia,3K7T8@414999|Opitutae	414999|Opitutae	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
YHH3_k127_5025332_3	382464.ABSI01000011_gene2626	6.695e-76	265.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,46SX6@74201|Verrucomicrobia,2IUHW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
YHH3_k127_5025332_5	56780.SYN_03523	2.199e-47	179.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42QX3@68525|delta/epsilon subdivisions,2WPC7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
YHH3_k127_5025332_0	583355.Caka_1434	1.916e-157	503.0	COG2805@1|root,COG2805@2|Bacteria,46SJF@74201|Verrucomicrobia,3K7CT@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH3_k127_5025332_2	349741.Amuc_0258	2.155e-90	307.0	COG0329@1|root,COG0329@2|Bacteria,46SDY@74201|Verrucomicrobia,2ITUK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EM	Dihydrodipicolinate synthetase family	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YHH3_k127_5025332_6	278957.ABEA03000082_gene2945	1.854e-38	152.0	COG0289@1|root,COG0289@2|Bacteria,46SPR@74201|Verrucomicrobia,3K7A2@414999|Opitutae	414999|Opitutae	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
YHH3_k127_5030136_0	1382306.JNIM01000001_gene1617	4.365e-111	368.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YHH3_k127_5030136_1	1089552.KI911559_gene1729	1.868e-94	314.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,2JPEB@204441|Rhodospirillales	204441|Rhodospirillales	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH3_k127_5052153_1	665571.STHERM_c18410	9.454e-82	277.0	COG3264@1|root,COG3264@2|Bacteria,2JBD8@203691|Spirochaetes	2|Bacteria	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
YHH3_k127_5052153_0	583355.Caka_1594	3.662e-92	333.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46W2M@74201|Verrucomicrobia,3K81K@414999|Opitutae	2|Bacteria	KLT	Sulfatase-modifying factor enzyme 1	egtB	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
YHH3_k127_5056382_1	583355.Caka_1424	8.989e-92	309.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,3K7BT@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
YHH3_k127_5056382_0	497964.CfE428DRAFT_2620	5.083e-107	358.0	COG0330@1|root,COG0330@2|Bacteria,46VDU@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH3_k127_5056382_2	497964.CfE428DRAFT_2621	1.464e-87	296.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
YHH3_k127_5058750_2	1183438.GKIL_1125	9.04e-08	54.0	COG4166@1|root,COG4166@2|Bacteria,1GR16@1117|Cyanobacteria	1117|Cyanobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
YHH3_k127_5058750_4	391587.KAOT1_17313	0.0008835	45.0	COG1719@1|root,COG1719@2|Bacteria,4NIZJ@976|Bacteroidetes,1I1NS@117743|Flavobacteriia	976|Bacteroidetes	S	Haem-NO-binding	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
YHH3_k127_5058750_0	761193.Runsl_3107	9.258e-61	222.0	COG2755@1|root,COG2755@2|Bacteria,4NIBN@976|Bacteroidetes,47NY7@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH3_k127_5058750_3	1274374.CBLK010000083_gene3878	6.764e-07	55.0	2CD8P@1|root,2Z9US@2|Bacteria,1TSC6@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5058750_1	247633.GP2143_05390	2.297e-22	99.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1J7I8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG4166 ABC-type oligopeptide transport system, periplasmic component	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
YHH3_k127_5081142_0	1122207.MUS1_15200	7.787e-129	421.0	COG1482@1|root,COG1482@2|Bacteria,1QE1E@1224|Proteobacteria,1RZ8T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	cell wall glycoprotein biosynthetic process	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	-
YHH3_k127_5081142_1	595460.RRSWK_03705	4.608e-108	361.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	VVA1382	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_509121_1	316067.Geob_1385	1.859e-50	183.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,43V4T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
YHH3_k127_509121_2	1238450.VIBNISOn1_620025	1.289e-44	168.0	COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,1RPV0@1236|Gammaproteobacteria,1XTFJ@135623|Vibrionales	135623|Vibrionales	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
YHH3_k127_509121_0	1183438.GKIL_3985	1.627e-56	205.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
YHH3_k127_5095479_1	1121897.AUGO01000002_gene2355	6.084e-31	124.0	COG5498@1|root,COG5498@2|Bacteria,4PI3C@976|Bacteroidetes,1I75X@117743|Flavobacteriia,2NY7K@237|Flavobacterium	976|Bacteroidetes	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5095479_0	382464.ABSI01000013_gene1558	7.354e-240	752.0	COG0457@1|root,COG0457@2|Bacteria,46W9Q@74201|Verrucomicrobia,2IVDS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5122620_3	1268072.PSAB_21925	2.646e-44	176.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	lgtD	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_5122620_2	395019.Bmul_2603	1.735e-55	205.0	COG1216@1|root,COG1216@2|Bacteria,1REVD@1224|Proteobacteria	1224|Proteobacteria	Q	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_5122620_0	583355.Caka_1407	1.025e-182	583.0	COG0064@1|root,COG0064@2|Bacteria,46S5X@74201|Verrucomicrobia,3K7TB@414999|Opitutae	414999|Opitutae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YHH3_k127_5122620_1	452637.Oter_2360	1.191e-180	577.0	COG0154@1|root,COG0154@2|Bacteria,46SCM@74201|Verrucomicrobia,3K7TV@414999|Opitutae	414999|Opitutae	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH3_k127_5122620_4	349741.Amuc_1783	3.408e-14	76.0	COG0721@1|root,COG0721@2|Bacteria,46WBS@74201|Verrucomicrobia,2IURF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
YHH3_k127_5122620_5	67315.JOBD01000038_gene4729	4.035e-07	52.0	COG0626@1|root,COG0626@2|Bacteria,2H1R1@201174|Actinobacteria	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
YHH3_k127_5128752_1	1396141.BATP01000040_gene2165	4.806e-40	163.0	COG2312@1|root,COG4870@1|root,COG5337@1|root,COG2312@2|Bacteria,COG4870@2|Bacteria,COG5337@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	cotH	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH,Erythro_esteras,LTD,Peptidase_C1
YHH3_k127_5128752_0	929713.NIASO_12030	5.238e-131	424.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1IP9I@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
YHH3_k127_5129521_1	583355.Caka_2562	1.276e-113	374.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,3K7NK@414999|Opitutae	74201|Verrucomicrobia	P	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
YHH3_k127_5129521_0	382464.ABSI01000021_gene419	1.425e-271	847.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,2ITZA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
YHH3_k127_5176529_2	583355.Caka_2715	2.806e-62	221.0	COG1994@1|root,COG1994@2|Bacteria,46SM2@74201|Verrucomicrobia,3K9SZ@414999|Opitutae	414999|Opitutae	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5176529_0	382464.ABSI01000021_gene443	6.439e-195	619.0	COG2326@1|root,COG2326@2|Bacteria,46UPR@74201|Verrucomicrobia,2IUNN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
YHH3_k127_5176529_1	382464.ABSI01000020_gene317	3.671e-73	256.0	COG1237@1|root,COG1237@2|Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
YHH3_k127_5176529_5	324925.Ppha_1324	2.336e-13	75.0	COG1433@1|root,COG1433@2|Bacteria,1FF7W@1090|Chlorobi	1090|Chlorobi	S	PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
YHH3_k127_5176529_4	765912.Thimo_0840	2.025e-20	93.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1N80T@1224|Proteobacteria,1S9DC@1236|Gammaproteobacteria,1WZ10@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0251 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
YHH3_k127_5176529_3	326297.Sama_1110	2.703e-33	132.0	COG0346@1|root,COG0346@2|Bacteria,1NB3U@1224|Proteobacteria,1SQES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_520427_3	933262.AXAM01000218_gene1658	2.405e-22	99.0	COG5304@1|root,COG5304@2|Bacteria,1NBCZ@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
YHH3_k127_520427_2	671143.DAMO_2895	2.086e-24	105.0	COG2929@1|root,COG2929@2|Bacteria,2NRAK@2323|unclassified Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
YHH3_k127_520427_0	1134474.O59_003370	3.166e-103	350.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,1FIHV@10|Cellvibrio	1236|Gammaproteobacteria	C	NAD(P)-binding Rossmann-like domain	pltA	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
YHH3_k127_520427_4	1117647.M5M_07695	6.17e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,1NAJI@1224|Proteobacteria,1SJ0Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_520427_1	278957.ABEA03000160_gene28	2.481e-83	282.0	COG4581@1|root,COG4581@2|Bacteria,46STC@74201|Verrucomicrobia,3K7CK@414999|Opitutae	414999|Opitutae	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
YHH3_k127_5214500_0	1453505.JASY01000006_gene1279	8.328e-54	209.0	COG3525@1|root,COG3525@2|Bacteria,4NH5U@976|Bacteroidetes,1IBP1@117743|Flavobacteriia,2NU7X@237|Flavobacterium	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20b
YHH3_k127_5233029_1	382464.ABSI01000011_gene2811	5.874e-16	85.0	COG0457@1|root,COG0457@2|Bacteria,46U59@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
YHH3_k127_5233029_0	382464.ABSI01000017_gene105	2.498e-149	484.0	COG4403@1|root,COG4403@2|Bacteria,46TSW@74201|Verrucomicrobia,2IVAH@203494|Verrucomicrobiae	2|Bacteria	V	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
YHH3_k127_5257715_10	452637.Oter_3743	1.649e-17	88.0	COG1314@1|root,COG1314@2|Bacteria,46T75@74201|Verrucomicrobia,3K89V@414999|Opitutae	414999|Opitutae	U	PFAM Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
YHH3_k127_5257715_2	382464.ABSI01000021_gene435	3.793e-88	304.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia,2IU4T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YHH3_k127_5257715_9	583355.Caka_2466	4.023e-25	113.0	COG1388@1|root,COG1388@2|Bacteria,46WB7@74201|Verrucomicrobia,3K845@414999|Opitutae	414999|Opitutae	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
YHH3_k127_5257715_5	794903.OPIT5_24220	1.027e-71	256.0	COG0223@1|root,COG0223@2|Bacteria,46SKS@74201|Verrucomicrobia,3K7UM@414999|Opitutae	414999|Opitutae	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YHH3_k127_5257715_1	583355.Caka_1896	9.074e-148	482.0	COG1160@1|root,COG1160@2|Bacteria,46SJY@74201|Verrucomicrobia,3K77B@414999|Opitutae	414999|Opitutae	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
YHH3_k127_5257715_0	382464.ABSI01000021_gene431	2.765e-164	524.0	COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,2ITGM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_5257715_7	382464.ABSI01000021_gene430	1.528e-48	178.0	COG1522@1|root,COG1522@2|Bacteria,46VEI@74201|Verrucomicrobia,2IU8W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
YHH3_k127_5257715_4	583355.Caka_1185	7.66e-72	254.0	COG1565@1|root,COG1565@2|Bacteria,46T7F@74201|Verrucomicrobia,3K7JD@414999|Opitutae	414999|Opitutae	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
YHH3_k127_5257715_8	583355.Caka_1186	8.336e-27	111.0	COG0227@1|root,COG0227@2|Bacteria,46TBF@74201|Verrucomicrobia,3K89C@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
YHH3_k127_5257715_3	42256.RradSPS_1755	6.108e-79	271.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
YHH3_k127_5257715_6	794903.OPIT5_10670	7.517e-50	181.0	COG0175@1|root,COG0175@2|Bacteria,46U3C@74201|Verrucomicrobia,3K7TU@414999|Opitutae	414999|Opitutae	C	Phosphoadenosine phosphosulfate reductase	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YHH3_k127_5310561_1	335543.Sfum_0943	1.222e-78	270.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,43065@68525|delta/epsilon subdivisions,2WV8S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_5310561_0	335543.Sfum_0581	1.5e-228	722.0	COG2202@1|root,COG2984@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2984@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS_3
YHH3_k127_5313688_0	1341155.FSS13T_21560	2.306e-44	175.0	COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YHH3_k127_5313688_2	876269.ARWA01000001_gene3320	0.0001471	52.0	COG1266@1|root,COG1266@2|Bacteria,1REZN@1224|Proteobacteria,2U7J7@28211|Alphaproteobacteria,3NB41@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
YHH3_k127_531610_0	1206726.BAFV01000053_gene3664	7.238e-154	492.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4FWIH@85025|Nocardiaceae	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YHH3_k127_531610_2	1173023.KE650771_gene4600	1.02e-90	317.0	COG2202@1|root,COG3829@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria,1JMXN@1189|Stigonemataceae	1117|Cyanobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CBS,CheB_methylest,CheR,CheR_N,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
YHH3_k127_531610_4	1124780.ANNU01000006_gene2946	8.692e-49	183.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
YHH3_k127_531610_1	382464.ABSI01000011_gene2618	1.557e-99	331.0	COG0668@1|root,COG0668@2|Bacteria,46V1Y@74201|Verrucomicrobia,2IUI5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
YHH3_k127_531610_3	452637.Oter_0842	7.633e-74	263.0	COG3137@1|root,COG3137@2|Bacteria,46TU0@74201|Verrucomicrobia,3K75A@414999|Opitutae	414999|Opitutae	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
YHH3_k127_5316420_1	1121033.AUCF01000011_gene1817	1.261e-09	58.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,2TSPP@28211|Alphaproteobacteria,2JQQJ@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
YHH3_k127_5316420_0	979556.MTES_1110	4.378e-62	244.0	COG3250@1|root,COG3250@2|Bacteria,2GM69@201174|Actinobacteria,4FN54@85023|Microbacteriaceae	201174|Actinobacteria	G	beta-mannosidase	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_5316420_2	234267.Acid_0038	8.779e-06	54.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_49N,Hepar_II_III,Hepar_II_III_N
YHH3_k127_54105_2	478749.BRYFOR_08109	6.743e-13	69.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
YHH3_k127_54105_0	1142394.PSMK_10000	4.682e-96	334.0	COG2211@1|root,COG2211@2|Bacteria,2J1EX@203682|Planctomycetes	203682|Planctomycetes	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
YHH3_k127_54105_1	1268240.ATFI01000001_gene2805	3.502e-66	240.0	COG1874@1|root,COG1874@2|Bacteria,4PNM8@976|Bacteroidetes,2G105@200643|Bacteroidia,4ATB9@815|Bacteroidaceae	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5436074_0	373994.Riv7116_5911	3.137e-106	356.0	COG0438@1|root,COG0438@2|Bacteria,1GI78@1117|Cyanobacteria,1HRRB@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YHH3_k127_5436074_1	111780.Sta7437_3658	9.923e-07	55.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1G2VA@1117|Cyanobacteria,3VIR0@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glycos_transf_2
YHH3_k127_5499614_0	583355.Caka_1567	2.049e-214	673.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,3K7DX@414999|Opitutae	414999|Opitutae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH3_k127_5499614_1	2880.D7FUJ9	1.961e-82	291.0	2CYCX@1|root,2S3MN@2759|Eukaryota	2759|Eukaryota	S	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
YHH3_k127_5535273_0	583355.Caka_2362	1.08e-61	214.0	COG0372@1|root,COG0372@2|Bacteria,46SBV@74201|Verrucomicrobia,3K7TE@414999|Opitutae	414999|Opitutae	H	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
YHH3_k127_5535273_1	583355.Caka_2363	2.933e-51	196.0	2CH0A@1|root,2ZANK@2|Bacteria,46V2X@74201|Verrucomicrobia,3K7YW@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5535273_2	420246.GTNG_1022	6.925e-34	134.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1WFSN@129337|Geobacillus	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
YHH3_k127_5539981_0	452637.Oter_1383	2.481e-170	539.0	COG1069@1|root,COG1069@2|Bacteria,46UI3@74201|Verrucomicrobia,3K769@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
YHH3_k127_5539981_3	279714.FuraDRAFT_1440	2.306e-19	89.0	COG4731@1|root,COG4731@2|Bacteria,1N19Y@1224|Proteobacteria,2VTB1@28216|Betaproteobacteria,2KRH2@206351|Neisseriales	206351|Neisseriales	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
YHH3_k127_5539981_1	946483.Cenrod_1749	4.149e-69	238.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,4ABGP@80864|Comamonadaceae	28216|Betaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
YHH3_k127_5539981_4	1123487.KB892839_gene227	1.968e-17	84.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,2KUR9@206389|Rhodocyclales	28216|Betaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
YHH3_k127_5539981_2	497964.CfE428DRAFT_0393	5.629e-45	174.0	COG4977@1|root,COG4977@2|Bacteria,46Z8I@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Peripla_BP_3
YHH3_k127_5573220_2	382464.ABSI01000011_gene2651	1.696e-203	644.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,2ITRX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YHH3_k127_5573220_16	583355.Caka_1671	8.465e-40	153.0	COG0200@1|root,COG0200@2|Bacteria,46VGD@74201|Verrucomicrobia,3K832@414999|Opitutae	414999|Opitutae	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
YHH3_k127_5573220_7	382464.ABSI01000011_gene2653	3.493e-63	224.0	COG0098@1|root,COG0098@2|Bacteria,46SUR@74201|Verrucomicrobia,2IUC7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
YHH3_k127_5573220_17	382464.ABSI01000011_gene2654	1.578e-38	147.0	COG0256@1|root,COG0256@2|Bacteria,46T7Z@74201|Verrucomicrobia,2IUJF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
YHH3_k127_5573220_11	452637.Oter_0211	7.285e-59	211.0	COG0097@1|root,COG0097@2|Bacteria,46SP9@74201|Verrucomicrobia,3K7WU@414999|Opitutae	414999|Opitutae	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
YHH3_k127_5573220_19	1007103.AFHW01000102_gene5368	2.239e-36	141.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,26WQU@186822|Paenibacillaceae	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
YHH3_k127_5573220_15	583355.Caka_1676	7.039e-42	157.0	COG0199@1|root,COG0199@2|Bacteria,46X64@74201|Verrucomicrobia,3K84A@414999|Opitutae	414999|Opitutae	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
YHH3_k127_5573220_8	278957.ABEA03000041_gene2073	4.521e-63	223.0	COG0094@1|root,COG0094@2|Bacteria,46SP7@74201|Verrucomicrobia,3K7AF@414999|Opitutae	414999|Opitutae	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
YHH3_k127_5573220_22	382464.ABSI01000011_gene2659	2.685e-18	87.0	COG0198@1|root,COG0198@2|Bacteria,46T3M@74201|Verrucomicrobia,2IUUE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal proteins 50S L24/mitochondrial 39S L24	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
YHH3_k127_5573220_14	382464.ABSI01000011_gene2660	9.825e-50	181.0	COG0093@1|root,COG0093@2|Bacteria,46VID@74201|Verrucomicrobia,2IUB7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
YHH3_k127_5573220_21	583355.Caka_1680	2.146e-29	121.0	COG0186@1|root,COG0186@2|Bacteria,46T6M@74201|Verrucomicrobia,3K88E@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
YHH3_k127_5573220_24	278957.ABEA03000071_gene3048	2.067e-11	66.0	COG0255@1|root,COG0255@2|Bacteria,46WKJ@74201|Verrucomicrobia,3K8FF@414999|Opitutae	414999|Opitutae	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
YHH3_k127_5573220_12	452637.Oter_0219	1.188e-54	194.0	COG0197@1|root,COG0197@2|Bacteria,46ST6@74201|Verrucomicrobia,3K7Z4@414999|Opitutae	414999|Opitutae	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
YHH3_k127_5573220_4	583355.Caka_1683	9.467e-94	311.0	COG0092@1|root,COG0092@2|Bacteria,46SN9@74201|Verrucomicrobia,3K776@414999|Opitutae	414999|Opitutae	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YHH3_k127_5573220_18	583355.Caka_1684	1.885e-37	144.0	COG0091@1|root,COG0091@2|Bacteria,46T5F@74201|Verrucomicrobia,3K89B@414999|Opitutae	414999|Opitutae	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
YHH3_k127_5573220_20	382464.ABSI01000011_gene2666	2.601e-36	139.0	COG0185@1|root,COG0185@2|Bacteria,46T4G@74201|Verrucomicrobia,2IUPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
YHH3_k127_5573220_3	583355.Caka_1687	3.755e-107	355.0	COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia,3K7DN@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YHH3_k127_5573220_23	583355.Caka_1688	1.093e-16	83.0	COG0089@1|root,COG0089@2|Bacteria,46WBX@74201|Verrucomicrobia,3K884@414999|Opitutae	414999|Opitutae	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
YHH3_k127_5573220_10	583355.Caka_1689	7.07e-61	218.0	COG0088@1|root,COG0088@2|Bacteria,46SWJ@74201|Verrucomicrobia,3K7CA@414999|Opitutae	414999|Opitutae	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YHH3_k127_5573220_5	583355.Caka_1690	2.615e-83	281.0	COG0087@1|root,COG0087@2|Bacteria,46U5V@74201|Verrucomicrobia,3K7BQ@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
YHH3_k127_5573220_13	452637.Oter_0227	8.788e-52	184.0	COG0051@1|root,COG0051@2|Bacteria,46SVV@74201|Verrucomicrobia,3K86C@414999|Opitutae	414999|Opitutae	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
YHH3_k127_5573220_1	583355.Caka_1707	0.0	1007.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,3K7PT@414999|Opitutae	414999|Opitutae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YHH3_k127_5573220_6	452637.Oter_0229	5.64e-70	239.0	COG0049@1|root,COG0049@2|Bacteria,46UH0@74201|Verrucomicrobia,3K7QA@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YHH3_k127_5573220_9	583355.Caka_1709	5.983e-61	214.0	COG0048@1|root,COG0048@2|Bacteria,46SQR@74201|Verrucomicrobia,3K7YQ@414999|Opitutae	414999|Opitutae	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
YHH3_k127_5573220_0	583355.Caka_2711	0.0	1858.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia,3K7EI@414999|Opitutae	414999|Opitutae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH3_k127_5573689_0	234267.Acid_4530	6.323e-138	449.0	2DB8U@1|root,2Z7SW@2|Bacteria,3Y3IM@57723|Acidobacteria	57723|Acidobacteria	S	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase
YHH3_k127_5573689_1	1166018.FAES_2240	2.205e-09	62.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,47JG2@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase C-terminal domain	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
YHH3_k127_5584745_3	452637.Oter_0004	9.611e-50	186.0	COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia,3K7BP@414999|Opitutae	414999|Opitutae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	-	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
YHH3_k127_5584745_1	999141.GME_05570	4.412e-119	392.0	COG0673@1|root,COG0673@2|Bacteria,1NVIW@1224|Proteobacteria,1SEMU@1236|Gammaproteobacteria,1XP1U@135619|Oceanospirillales	135619|Oceanospirillales	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_5584745_4	927658.AJUM01000022_gene1250	8.483e-13	74.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,2FS35@200643|Bacteroidia,3XKWT@558415|Marinilabiliaceae	976|Bacteroidetes	O	Hsp20/alpha crystallin family	hsp20	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YHH3_k127_5584745_5	345341.KUTG_09448	1.689e-08	62.0	COG0071@1|root,COG0071@2|Bacteria,2IRG0@201174|Actinobacteria,4E6ZT@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YHH3_k127_5584745_2	1479237.JMLY01000001_gene1196	2.948e-76	288.0	COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RN1E@1236|Gammaproteobacteria,464FG@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH3_k127_5584745_0	583355.Caka_2353	4.387e-126	419.0	COG1196@1|root,COG1196@2|Bacteria,46TT8@74201|Verrucomicrobia,3K7E6@414999|Opitutae	414999|Opitutae	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YHH3_k127_5590957_3	1288963.ADIS_2455	2.665e-09	61.0	COG4409@1|root,COG4409@2|Bacteria,4P27R@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
YHH3_k127_5590957_0	1122176.KB903533_gene2443	4.782e-214	672.0	COG0673@1|root,COG0673@2|Bacteria,4NIF1@976|Bacteroidetes,1IVYW@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_5590957_1	1210884.HG799463_gene9540	1.128e-209	676.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
YHH3_k127_5590957_2	471854.Dfer_4325	7.969e-16	80.0	COG3661@1|root,COG3661@2|Bacteria,4NGUW@976|Bacteroidetes,47MDP@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 67 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_67N
YHH3_k127_5603780_1	714943.Mucpa_1298	0.0008483	42.0	COG1961@1|root,COG1961@2|Bacteria,4NHW0@976|Bacteroidetes,1IR5S@117747|Sphingobacteriia	976|Bacteroidetes	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
YHH3_k127_5603780_0	926550.CLDAP_00570	1.709e-107	370.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG3829@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,2G7J9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
YHH3_k127_5606056_1	1333507.AUTQ01000131_gene467	1.362e-51	194.0	COG0591@1|root,COG0591@2|Bacteria,1MW6E@1224|Proteobacteria,1RXYK@1236|Gammaproteobacteria,2Q5DK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_5606056_0	1123278.KB893522_gene2527	3.458e-73	252.0	COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,47N9K@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,DUF1080
YHH3_k127_5620910_3	583355.Caka_1078	3.161e-50	184.0	COG4399@1|root,COG4399@2|Bacteria	2|Bacteria	-	-	yheB	-	-	-	-	-	-	-	-	-	-	-	DUF445
YHH3_k127_5620910_0	1396141.BATP01000056_gene3263	4.765e-158	511.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	ynaJ	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2
YHH3_k127_5620910_1	452637.Oter_1344	3.133e-157	509.0	COG4225@1|root,COG4225@2|Bacteria,46TG3@74201|Verrucomicrobia,3K902@414999|Opitutae	414999|Opitutae	S	PFAM glycosyl hydrolase family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
YHH3_k127_5620910_4	1236541.BALL01000016_gene2304	1.57e-29	118.0	COG2314@1|root,COG2314@2|Bacteria,1N8CV@1224|Proteobacteria,1T0FD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4864,TM2,zinc_ribbon_2
YHH3_k127_5620910_5	1236541.BALL01000016_gene2305	2.02e-28	118.0	2DRWU@1|root,33DFI@2|Bacteria,1NPHB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5620910_2	382464.ABSI01000010_gene3578	1.062e-57	204.0	COG0624@1|root,COG0624@2|Bacteria,46UH8@74201|Verrucomicrobia,2ITIW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YHH3_k127_5630532_1	1242864.D187_008628	4.827e-09	65.0	COG3266@1|root,COG3266@2|Bacteria,1N3DG@1224|Proteobacteria	1224|Proteobacteria	S	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
YHH3_k127_5630532_0	1121101.HMPREF1532_00976	3.343e-226	722.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,2FN74@200643|Bacteroidia,4AKXQ@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,Gal_mutarotas_2,Glyco_hydro_31
YHH3_k127_5632474_6	583355.Caka_2147	2.287e-05	46.0	COG0272@1|root,COG0272@2|Bacteria,46WS4@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5632474_5	118168.MC7420_5234	1.102e-05	49.0	COG5563@1|root,COG5563@2|Bacteria,1GIA8@1117|Cyanobacteria,1HFHC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5632474_2	583355.Caka_2308	6.924e-115	387.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46USH@74201|Verrucomicrobia,3K738@414999|Opitutae	414999|Opitutae	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
YHH3_k127_5632474_0	583355.Caka_2307	3.607e-192	610.0	COG0322@1|root,COG0322@2|Bacteria,46SAJ@74201|Verrucomicrobia,3K7BJ@414999|Opitutae	414999|Opitutae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
YHH3_k127_5632474_1	583355.Caka_1512	1.328e-152	495.0	COG1624@1|root,COG1762@1|root,COG1624@2|Bacteria,COG1762@2|Bacteria,46TVS@74201|Verrucomicrobia,3K7HC@414999|Opitutae	414999|Opitutae	H	Diadenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N,PTS_EIIA_2
YHH3_k127_5632474_4	382464.ABSI01000014_gene1470	1.653e-20	106.0	29ZR2@1|root,30MRV@2|Bacteria,46XMI@74201|Verrucomicrobia,2IW71@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5632474_3	926569.ANT_22730	4.886e-54	200.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH3_k127_5632474_7	771875.Ferpe_0712	0.0002462	50.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
YHH3_k127_5691689_0	558169.AGAV01000005_gene2556	2.321e-121	402.0	COG2079@1|root,COG2079@2|Bacteria,1TSD7@1239|Firmicutes,4HEZJ@91061|Bacilli	91061|Bacilli	S	protein involved in propionate catabolism	-	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
YHH3_k127_5691689_1	713586.KB900536_gene376	2.987e-58	207.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
YHH3_k127_5695342_2	714943.Mucpa_6741	9.819e-32	126.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,1IPWK@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycoside hydrolase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_106,Glyco_hydro_2_N
YHH3_k127_5695342_1	1123277.KB893174_gene5922	6.122e-97	355.0	COG2152@1|root,COG2152@2|Bacteria,4PN24@976|Bacteroidetes,47MK6@768503|Cytophagia	976|Bacteroidetes	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5695342_0	382464.ABSI01000001_gene4243	5.12e-276	886.0	COG1554@1|root,COG1554@2|Bacteria,46TM2@74201|Verrucomicrobia,2IV0H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
YHH3_k127_5710198_1	1396141.BATP01000056_gene3206	5.431e-17	96.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Peptidase_C11
YHH3_k127_5710198_0	997296.PB1_10719	1.127e-18	102.0	COG4935@1|root,COG5184@1|root,COG4935@2|Bacteria,COG5184@2|Bacteria,1TS5I@1239|Firmicutes,4HFME@91061|Bacilli	91061|Bacilli	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2,SLH,fn3
YHH3_k127_5713044_4	583355.Caka_1583	5.991e-48	179.0	COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia,3K73M@414999|Opitutae	414999|Opitutae	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YHH3_k127_5713044_1	583355.Caka_1584	4.915e-133	439.0	COG0305@1|root,COG0305@2|Bacteria,46SKM@74201|Verrucomicrobia,3K7R2@414999|Opitutae	414999|Opitutae	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
YHH3_k127_5713044_2	452637.Oter_2332	1.243e-52	190.0	COG0359@1|root,COG0359@2|Bacteria,46SYE@74201|Verrucomicrobia,3K82A@414999|Opitutae	414999|Opitutae	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
YHH3_k127_5713044_3	583355.Caka_1586	9.383e-49	178.0	COG0629@1|root,COG0629@2|Bacteria,46VZR@74201|Verrucomicrobia,3K80H@414999|Opitutae	414999|Opitutae	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YHH3_k127_5713044_8	452637.Oter_2287	2.844e-13	74.0	COG0360@1|root,COG0360@2|Bacteria,46TBG@74201|Verrucomicrobia,3K8BM@414999|Opitutae	414999|Opitutae	J	Ribosomal protein S6	-	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
YHH3_k127_5713044_5	583355.Caka_1588	2.263e-44	168.0	COG0193@1|root,COG0193@2|Bacteria,46T09@74201|Verrucomicrobia,3K7ZI@414999|Opitutae	414999|Opitutae	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
YHH3_k127_5713044_6	794903.OPIT5_19640	1.101e-34	140.0	COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia,3K784@414999|Opitutae	414999|Opitutae	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
YHH3_k127_5713044_0	583355.Caka_1750	5.366e-262	823.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,3K7DV@414999|Opitutae	414999|Opitutae	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
YHH3_k127_5713044_7	583355.Caka_1751	6.526e-23	102.0	COG0037@1|root,COG0037@2|Bacteria,46YXN@74201|Verrucomicrobia,3K8AF@414999|Opitutae	414999|Opitutae	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
YHH3_k127_5717418_3	290398.Csal_1541	5.811e-12	68.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1XI9W@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YHH3_k127_5717418_1	583355.Caka_1109	7.396e-102	342.0	COG0524@1|root,COG0524@2|Bacteria,46W0T@74201|Verrucomicrobia,3K79H@414999|Opitutae	414999|Opitutae	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH3_k127_5717418_2	452637.Oter_0054	1.06e-45	173.0	2AX8K@1|root,31P7E@2|Bacteria,46XUD@74201|Verrucomicrobia,3K874@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5717418_0	768671.ThimaDRAFT_1447	2.601e-108	370.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1SMH6@1236|Gammaproteobacteria,1X0JB@135613|Chromatiales	135613|Chromatiales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YHH3_k127_5723330_2	382464.ABSI01000011_gene3187	6.704e-45	170.0	COG0815@1|root,COG0815@2|Bacteria,46W4F@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the fatty acyl group on membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_5723330_0	404589.Anae109_2633	6.809e-90	323.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MJD@68525|delta/epsilon subdivisions,2WJC4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	epsN	-	-	ko:K19430	-	-	-	-	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
YHH3_k127_5723330_1	857087.Metme_1196	9.488e-52	188.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,1XE47@135618|Methylococcales	135618|Methylococcales	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH3_k127_5729405_2	1397528.Q671_00130	5.751e-160	511.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,1RP8C@1236|Gammaproteobacteria,1XIZR@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	-	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
YHH3_k127_5729405_1	1056820.KB900674_gene2549	4.979e-219	683.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,1RP49@1236|Gammaproteobacteria,2PMS9@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	Saccharopine dehydrogenase C-terminal domain	HA62_29220	-	1.5.1.43,1.5.1.7	ko:K00290,ko:K13746	ko00300,ko00310,ko00330,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map00330,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R09079,R09080	RC00053,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
YHH3_k127_5729405_0	1195236.CTER_3530	1.123e-254	800.0	COG1166@1|root,COG1166@2|Bacteria,1UZ22@1239|Firmicutes,24EU9@186801|Clostridia	186801|Clostridia	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
YHH3_k127_5729405_3	452637.Oter_2483	3.114e-66	229.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia,3K7CW@414999|Opitutae	414999|Opitutae	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
YHH3_k127_5749073_1	382464.ABSI01000011_gene2334	2.771e-151	483.0	COG3696@1|root,COG3696@2|Bacteria,46USJ@74201|Verrucomicrobia,2IVD5@203494|Verrucomicrobiae	74201|Verrucomicrobia	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
YHH3_k127_5749073_0	382464.ABSI01000015_gene626	7.581e-153	494.0	COG0845@1|root,COG0845@2|Bacteria,46ZJV@74201|Verrucomicrobia,2IVCQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YHH3_k127_5794280_3	886293.Sinac_3170	8.053e-08	63.0	COG2165@1|root,COG2165@2|Bacteria,2J2XK@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_10
YHH3_k127_5794280_1	278957.ABEA03000019_gene1946	5.332e-17	86.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,46SFK@74201|Verrucomicrobia,3K7FG@414999|Opitutae	414999|Opitutae	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
YHH3_k127_581363_0	583355.Caka_0671	1.354e-65	229.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,46UXA@74201|Verrucomicrobia,3K80M@414999|Opitutae	414999|Opitutae	P	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
YHH3_k127_581363_1	1191523.MROS_0796	2.972e-41	156.0	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
YHH3_k127_581363_2	583355.Caka_2267	7.234e-19	94.0	COG0810@1|root,COG0810@2|Bacteria,46WRI@74201|Verrucomicrobia,3K8HB@414999|Opitutae	414999|Opitutae	M	Biopolymer transporter TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH3_k127_5831592_0	382464.ABSI01000021_gene448	2.033e-58	230.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH3_k127_5831592_1	1048983.EL17_09135	0.0001193	46.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,47J9W@768503|Cytophagia	976|Bacteroidetes	EG	PFAM RhaT l-rhamnose-proton symport 2	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
YHH3_k127_5836337_1	382464.ABSI01000016_gene650	3.531e-34	138.0	COG0839@1|root,COG0839@2|Bacteria,46VSH@74201|Verrucomicrobia,2IUHV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YHH3_k127_5836337_2	278957.ABEA03000121_gene3926	4.853e-30	121.0	COG0713@1|root,COG0713@2|Bacteria,46YZN@74201|Verrucomicrobia,3K88N@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YHH3_k127_5836337_0	583355.Caka_2579	2.034e-210	671.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,3K73G@414999|Opitutae	414999|Opitutae	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
YHH3_k127_5836337_3	382464.ABSI01000016_gene653	3.668e-15	80.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,2ITG7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YHH3_k127_5957119_1	382464.ABSI01000010_gene3572	2.055e-108	354.0	COG1509@1|root,COG1509@2|Bacteria,46SVQ@74201|Verrucomicrobia,2ITNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Lysine-2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,LAM_C,Radical_SAM
YHH3_k127_5957119_3	583355.Caka_2004	1.437e-18	89.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
YHH3_k127_5957119_2	395961.Cyan7425_1014	1.053e-63	241.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	celC	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	BACON,CBM_6,Calx-beta,Cellulase,F5_F8_type_C,ThuA
YHH3_k127_5957119_0	583355.Caka_1978	9.935e-143	459.0	COG0505@1|root,COG0505@2|Bacteria,46TDX@74201|Verrucomicrobia,3K72S@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
YHH3_k127_5961271_2	316067.Geob_2220	2.192e-68	235.0	COG3576@1|root,COG3576@2|Bacteria,1N11C@1224|Proteobacteria,42USB@68525|delta/epsilon subdivisions,2WQDV@28221|Deltaproteobacteria,43V40@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
YHH3_k127_5961271_1	351348.Maqu_2661	3.081e-87	295.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,4679W@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
YHH3_k127_5961271_0	768671.ThimaDRAFT_0421	5.13e-156	508.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,1WYPQ@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH3_k127_5973390_2	452637.Oter_0658	1.232e-54	194.0	COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia,3K74R@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH3_k127_5973390_0	583355.Caka_0695	0.0	1231.0	COG0187@1|root,COG0187@2|Bacteria,46TW5@74201|Verrucomicrobia,3K7GR@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH3_k127_5973390_1	497964.CfE428DRAFT_0598	1.683e-81	277.0	COG0512@1|root,COG0512@2|Bacteria,46SN1@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	PFAM glutamine amidotransferase class-I	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YHH3_k127_6001777_0	452637.Oter_2005	1.363e-184	593.0	COG2844@1|root,COG2844@2|Bacteria,46SI6@74201|Verrucomicrobia,3K7SE@414999|Opitutae	414999|Opitutae	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
YHH3_k127_6001777_1	583355.Caka_2169	1.22e-11	66.0	COG2203@1|root,COG3605@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG4191@2|Bacteria,46SAZ@74201|Verrucomicrobia,3K7H5@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
YHH3_k127_6005961_0	382464.ABSI01000010_gene3501	1.249e-121	399.0	COG0673@1|root,COG0673@2|Bacteria,46W1B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_6005961_1	382464.ABSI01000010_gene3506	6.059e-61	216.0	COG2207@1|root,COG2207@2|Bacteria,46TQG@74201|Verrucomicrobia,2IW02@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
YHH3_k127_601099_4	1183438.GKIL_1078	1.754e-12	76.0	2BZB1@1|root,32R4P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_601099_5	1121091.AUMP01000006_gene4105	0.0001124	47.0	2DTBP@1|root,33JKJ@2|Bacteria,1VKDH@1239|Firmicutes,4I0AV@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_601099_3	583355.Caka_2765	2.236e-20	102.0	COG0810@1|root,COG0810@2|Bacteria,46WU0@74201|Verrucomicrobia,3K8C0@414999|Opitutae	414999|Opitutae	M	TonB C terminal	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_2
YHH3_k127_601099_2	583355.Caka_2764	3.554e-39	149.0	COG0848@1|root,COG0848@2|Bacteria,46T4F@74201|Verrucomicrobia,3K8EU@414999|Opitutae	414999|Opitutae	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH3_k127_601099_0	583355.Caka_2763	2.798e-68	239.0	COG0811@1|root,COG0811@2|Bacteria,46V1A@74201|Verrucomicrobia,3K7TP@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
YHH3_k127_601099_1	583355.Caka_2762	6.347e-55	203.0	COG0524@1|root,COG0524@2|Bacteria,46TT7@74201|Verrucomicrobia,3K7V3@414999|Opitutae	414999|Opitutae	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH3_k127_6013552_0	278957.ABEA03000180_gene2021	2.579e-228	720.0	COG1178@1|root,COG1178@2|Bacteria,46SFB@74201|Verrucomicrobia,3K7UZ@414999|Opitutae	414999|Opitutae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
YHH3_k127_6086808_1	382464.ABSI01000002_gene4376	3.508e-118	389.0	COG1477@1|root,COG1477@2|Bacteria,46V70@74201|Verrucomicrobia,2IUN9@203494|Verrucomicrobiae	2|Bacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
YHH3_k127_6086808_0	382464.ABSI01000002_gene4375	1.261e-143	460.0	COG2878@1|root,COG2878@2|Bacteria	2|Bacteria	C	electron transfer activity	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_7
YHH3_k127_6086808_2	382464.ABSI01000002_gene4374	1.256e-54	193.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH3_k127_6102022_4	497964.CfE428DRAFT_3056	2.669e-59	212.0	COG1070@1|root,COG1070@2|Bacteria,46S5Z@74201|Verrucomicrobia	74201|Verrucomicrobia	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.5,2.7.1.51	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014,R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
YHH3_k127_6102022_1	382464.ABSI01000007_gene4147	9.366e-100	331.0	COG0247@1|root,COG0247@2|Bacteria,46SAS@74201|Verrucomicrobia,2IUWH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
YHH3_k127_6102022_0	382464.ABSI01000007_gene4146	5.128e-210	665.0	COG1139@1|root,COG1139@2|Bacteria,46SBN@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
YHH3_k127_6102022_6	452637.Oter_1395	1.16e-41	160.0	COG1556@1|root,COG1556@2|Bacteria,46TAQ@74201|Verrucomicrobia,3K821@414999|Opitutae	414999|Opitutae	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
YHH3_k127_6102022_2	396588.Tgr7_2595	7.903e-84	285.0	COG1028@1|root,COG1028@2|Bacteria,1MUAY@1224|Proteobacteria,1S1XJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH3_k127_6102022_7	452637.Oter_1432	1.464e-24	111.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia,3K9TR@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_6102022_5	391623.TERMP_00782	6.331e-45	171.0	COG4902@1|root,arCOG03957@2157|Archaea,2Y2WW@28890|Euryarchaeota,243M5@183968|Thermococci	183968|Thermococci	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
YHH3_k127_6102022_3	1185876.BN8_00463	1.063e-76	267.0	2DB8U@1|root,2Z7SW@2|Bacteria,4NEUK@976|Bacteroidetes,47KH1@768503|Cytophagia	976|Bacteroidetes	S	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase
YHH3_k127_611227_0	794903.OPIT5_19570	6.761e-159	511.0	COG0172@1|root,COG0172@2|Bacteria,46S70@74201|Verrucomicrobia,3K7B7@414999|Opitutae	414999|Opitutae	J	PFAM tRNA synthetase class II (G H P and S)	-	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YHH3_k127_611227_1	485915.Dret_1332	2.868e-83	288.0	COG0204@1|root,COG0204@2|Bacteria,1PY44@1224|Proteobacteria,42NR4@68525|delta/epsilon subdivisions,2WKKQ@28221|Deltaproteobacteria,2MAGC@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH3_k127_6116899_0	530564.Psta_1178	1.324e-71	259.0	COG1657@1|root,COG3345@1|root,COG1657@2|Bacteria,COG3345@2|Bacteria,2IZER@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
YHH3_k127_6116899_2	761193.Runsl_2930	0.0001177	54.0	COG3250@1|root,COG3250@2|Bacteria,4NH5T@976|Bacteroidetes,47JCD@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF5127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127
YHH3_k127_6116899_1	56107.Cylst_3847	1.157e-11	72.0	COG5293@1|root,COG5293@2|Bacteria,1GIEQ@1117|Cyanobacteria,1HRDV@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised protein conserved in bacteria (DUF2326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2326
YHH3_k127_6160355_4	176280.SE_0936	6.057e-06	49.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,4GXK5@90964|Staphylococcaceae	91061|Bacilli	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
YHH3_k127_6160355_1	331869.BAL199_15968	1.595e-86	293.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2TQQ5@28211|Alphaproteobacteria,4BPDU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Serine acetyltransferase, N-terminal	cysE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
YHH3_k127_6160355_0	382464.ABSI01000010_gene3557	1.132e-103	346.0	COG4152@1|root,COG4152@2|Bacteria	2|Bacteria	S	ATPase activity	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YHH3_k127_6160355_2	382464.ABSI01000010_gene3558	6.993e-78	279.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YHH3_k127_6160355_3	519989.ECTPHS_09672	4.819e-40	156.0	COG0500@1|root,COG2226@2|Bacteria,1QWR5@1224|Proteobacteria,1T2WY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	rRNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
YHH3_k127_6209136_0	583355.Caka_1780	7.986e-53	198.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YHH3_k127_6234517_0	382464.ABSI01000011_gene3153	4.975e-242	760.0	COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,2ITMG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Anticodon binding domain	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
YHH3_k127_6234517_1	382464.ABSI01000011_gene3071	4.928e-186	592.0	COG0008@1|root,COG0008@2|Bacteria,46SJ3@74201|Verrucomicrobia,2ITYY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH3_k127_6234517_3	583355.Caka_1921	3.771e-43	167.0	COG3608@1|root,COG3608@2|Bacteria	2|Bacteria	G	succinylglutamate desuccinylase aspartoacylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA,DUF2817
YHH3_k127_6234517_4	1306174.JODP01000020_gene470	9.597e-26	111.0	COG0642@1|root,COG4251@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,2I2M2@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg,dCache_1
YHH3_k127_6234517_2	1396141.BATP01000026_gene1015	4.838e-56	200.0	COG4102@1|root,COG4102@2|Bacteria,46YXZ@74201|Verrucomicrobia,2ITT0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH3_k127_6250514_1	1297742.A176_00643	2.851e-25	108.0	COG3409@1|root,COG3409@2|Bacteria,1QEQE@1224|Proteobacteria,434PQ@68525|delta/epsilon subdivisions,2WZ0Y@28221|Deltaproteobacteria,2Z135@29|Myxococcales	28221|Deltaproteobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
YHH3_k127_6250514_4	631362.Thi970DRAFT_00342	2.012e-17	89.0	2E0F1@1|root,32W1E@2|Bacteria,1NFKH@1224|Proteobacteria,1SF1Z@1236|Gammaproteobacteria,1X1GM@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6250514_0	1265505.ATUG01000001_gene4606	4.574e-38	157.0	COG3409@1|root,COG3409@2|Bacteria,1RBD0@1224|Proteobacteria	1224|Proteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1
YHH3_k127_6252985_1	243090.RB10048	4.276e-122	408.0	COG2755@1|root,COG2755@2|Bacteria,2IWTR@203682|Planctomycetes	203682|Planctomycetes	E	sialic acid-specific 9-O-acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
YHH3_k127_6252985_0	583355.Caka_2820	1.631e-138	453.0	COG0513@1|root,COG0513@2|Bacteria	2|Bacteria	L	helicase activity	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
YHH3_k127_6285196_0	1191523.MROS_0432	4.126e-197	629.0	COG0653@1|root,COG0653@2|Bacteria	2|Bacteria	U	protein targeting	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH3_k127_6295642_0	452637.Oter_0645	8.366e-55	211.0	COG2887@1|root,COG2887@2|Bacteria,46SDQ@74201|Verrucomicrobia,3K85H@414999|Opitutae	414999|Opitutae	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
YHH3_k127_6295642_1	452637.Oter_0644	2.35e-32	132.0	COG1074@1|root,COG1074@2|Bacteria,46SF0@74201|Verrucomicrobia,3K7V5@414999|Opitutae	414999|Opitutae	L	PD-(D/E)XK nuclease superfamily	-	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH3_k127_6300915_1	382464.ABSI01000005_gene1280	1.172e-166	540.0	COG0473@1|root,COG0473@2|Bacteria,46S4R@74201|Verrucomicrobia,2ITY1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH3_k127_6300915_2	452637.Oter_3180	2.601e-136	447.0	COG1236@1|root,COG1236@2|Bacteria,46SQ0@74201|Verrucomicrobia,3K7R4@414999|Opitutae	414999|Opitutae	J	Beta-Casp domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,Lactamase_B,RMMBL
YHH3_k127_6300915_6	452637.Oter_3181	3.593e-34	136.0	COG2967@1|root,COG2967@2|Bacteria,46T44@74201|Verrucomicrobia,3K84K@414999|Opitutae	414999|Opitutae	P	ApaG domain	-	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
YHH3_k127_6300915_0	583355.Caka_1289	6.148e-238	745.0	COG0138@1|root,COG0138@2|Bacteria,46S5H@74201|Verrucomicrobia,3K7HP@414999|Opitutae	414999|Opitutae	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
YHH3_k127_6300915_5	1279009.ADICEAN_04118	1.387e-39	161.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes,47KZN@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
YHH3_k127_6300915_3	382464.ABSI01000007_gene4089	1.237e-122	402.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia,2IU0G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 3	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH3_k127_6300915_4	583355.Caka_1269	6.571e-67	239.0	COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia,3K7V0@414999|Opitutae	414999|Opitutae	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
YHH3_k127_6321314_0	404589.Anae109_3474	2.434e-92	323.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,42U1I@68525|delta/epsilon subdivisions,2WQQV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_core,Transglut_i_TM
YHH3_k127_6321314_1	1151126.AQYI01000006_gene2751	1.093e-14	86.0	COG4932@1|root,COG4932@2|Bacteria,2HU92@201174|Actinobacteria,4FSW9@85023|Microbacteriaceae	201174|Actinobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YHH3_k127_632601_1	583355.Caka_1761	1.948e-63	224.0	COG1966@1|root,COG1966@2|Bacteria,46V26@74201|Verrucomicrobia,3K9J7@414999|Opitutae	414999|Opitutae	T	PFAM carbon starvation protein CstA	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
YHH3_k127_632601_0	583355.Caka_1769	2.137e-70	244.0	COG0307@1|root,COG0307@2|Bacteria,46SU1@74201|Verrucomicrobia,3K7ZH@414999|Opitutae	414999|Opitutae	H	TIGRFAM riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
YHH3_k127_632601_2	583355.Caka_0624	2.472e-37	144.0	COG0155@1|root,COG0155@2|Bacteria,46U85@74201|Verrucomicrobia,3K77C@414999|Opitutae	414999|Opitutae	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
YHH3_k127_6330945_1	452637.Oter_1455	6.526e-68	243.0	COG0845@1|root,COG0845@2|Bacteria,46US2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YHH3_k127_6330945_0	382464.ABSI01000006_gene840	7.805e-74	268.0	COG1538@1|root,COG1538@2|Bacteria,46TY1@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YHH3_k127_6330945_4	1187851.A33M_3635	3.162e-21	95.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,Rhodanese
YHH3_k127_6330945_3	314231.FP2506_04336	3.579e-24	105.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,2PK80@255475|Aurantimonadaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	nolR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22042	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
YHH3_k127_6330945_2	382464.ABSI01000006_gene837	7.995e-25	106.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,2IUHZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH3_k127_6332057_1	269799.Gmet_1651	7.063e-109	365.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,43US6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH3_k127_6332057_0	880072.Desac_1402	3.792e-157	504.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2MR8V@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YHH3_k127_6368798_3	317936.Nos7107_2780	1.433e-56	213.0	COG5002@1|root,COG5002@2|Bacteria,1GQDS@1117|Cyanobacteria,1HME7@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YHH3_k127_6368798_2	382464.ABSI01000007_gene4118	3.546e-86	291.0	COG0745@1|root,COG0745@2|Bacteria,46TFB@74201|Verrucomicrobia,2IUEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YHH3_k127_6368798_0	595460.RRSWK_00701	4.041e-121	407.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,FGE-sulfatase,Lactamase_B_2,PD40,Peptidase_S9
YHH3_k127_6368798_1	1121459.AQXE01000008_gene842	5.272e-97	326.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42M8N@68525|delta/epsilon subdivisions,2WK7T@28221|Deltaproteobacteria,2M8BS@213115|Desulfovibrionales	28221|Deltaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH3_k127_6385583_0	583355.Caka_2853	8.276e-189	595.0	COG0556@1|root,COG0556@2|Bacteria,46SF2@74201|Verrucomicrobia,3K76Z@414999|Opitutae	414999|Opitutae	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH3_k127_6385583_1	1195246.AGRI_00060	3.793e-142	460.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,463Y3@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
YHH3_k127_6475801_2	382464.ABSI01000002_gene4375	8.31e-65	223.0	COG2878@1|root,COG2878@2|Bacteria	2|Bacteria	C	electron transfer activity	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_7
YHH3_k127_6475801_1	382464.ABSI01000002_gene4374	5.183e-144	458.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH3_k127_6475801_0	382464.ABSI01000002_gene4374	0.0	1199.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH3_k127_6483627_3	583355.Caka_2271	1.332e-27	122.0	2E0WS@1|root,32WDT@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
YHH3_k127_6483627_0	1444711.CCJF01000005_gene1483	4.714e-143	463.0	COG3842@1|root,COG3842@2|Bacteria,2JFST@204428|Chlamydiae	204428|Chlamydiae	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
YHH3_k127_6483627_1	1396141.BATP01000004_gene5846	1.098e-96	324.0	COG1176@1|root,COG1176@2|Bacteria,46SXN@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
YHH3_k127_6483627_2	765952.PUV_07590	5.461e-87	294.0	COG1177@1|root,COG1177@2|Bacteria,2JFN9@204428|Chlamydiae	204428|Chlamydiae	P	Binding-protein-dependent transport system inner membrane component	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
YHH3_k127_6483627_4	765952.PUV_07580	1.393e-20	93.0	COG0687@1|root,COG0687@2|Bacteria,2JGD6@204428|Chlamydiae	204428|Chlamydiae	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
YHH3_k127_6549301_1	177437.HRM2_07790	2.851e-112	373.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,2MJA8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
YHH3_k127_6549301_2	1122194.AUHU01000007_gene92	6.337e-99	332.0	COG3507@1|root,COG3507@2|Bacteria,1R10E@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
YHH3_k127_6549301_0	589865.DaAHT2_1405	1.113e-154	496.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42MFI@68525|delta/epsilon subdivisions,2WKXD@28221|Deltaproteobacteria,2MM6V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_6572033_0	714943.Mucpa_6741	8.483e-303	946.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,1IPWK@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycoside hydrolase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_106,Glyco_hydro_2_N
YHH3_k127_6577974_0	1396141.BATP01000023_gene628	1.504e-68	242.0	COG0463@1|root,COG0463@2|Bacteria,46UW3@74201|Verrucomicrobia,2IVC7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_6577974_1	1229205.BUPH_03261	3.566e-06	55.0	COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,2VIYA@28216|Betaproteobacteria,1JZSG@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	amp-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
YHH3_k127_6581414_3	382464.ABSI01000012_gene2239	1.805e-47	187.0	COG0784@1|root,COG2208@1|root,COG0784@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	DUF4388,PAS,PAS_9,Response_reg,SpoIIE
YHH3_k127_6581414_4	1089548.KI783301_gene1728	1.214e-06	55.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,4HINR@91061|Bacilli	91061|Bacilli	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
YHH3_k127_6581414_0	583355.Caka_1050	6.197e-144	466.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia,3K761@414999|Opitutae	414999|Opitutae	C	AAA domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
YHH3_k127_6581414_1	794903.OPIT5_01645	1.214e-107	359.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia,3K793@414999|Opitutae	414999|Opitutae	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
YHH3_k127_6581414_2	583355.Caka_1048	3.602e-88	306.0	COG0728@1|root,COG0728@2|Bacteria,46SH1@74201|Verrucomicrobia,3K78B@414999|Opitutae	414999|Opitutae	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YHH3_k127_6628790_3	794903.OPIT5_27975	7.897e-34	134.0	COG1995@1|root,COG1995@2|Bacteria,46SNQ@74201|Verrucomicrobia,3K7JT@414999|Opitutae	414999|Opitutae	C	Belongs to the PdxA family	-	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
YHH3_k127_6628790_1	382464.ABSI01000005_gene1089	5.661e-74	257.0	COG1043@1|root,COG1043@2|Bacteria,46SQN@74201|Verrucomicrobia,2IU6J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Udp N-acetylglucosamine O-acyltransferase; Domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_11,Hexapep
YHH3_k127_6628790_2	794903.OPIT5_25535	6.54e-72	248.0	2C0ZJ@1|root,33VV4@2|Bacteria,46VGY@74201|Verrucomicrobia,3K7JZ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6628790_4	335543.Sfum_2581	1.137e-15	83.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2MQN9@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
YHH3_k127_6628790_0	382464.ABSI01000012_gene2280	1.043e-139	446.0	COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia,2IU0R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH3_k127_6633519_1	457415.HMPREF1006_01517	4.447e-66	230.0	COG1063@1|root,COG1063@2|Bacteria,3TA9N@508458|Synergistetes	508458|Synergistetes	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_6633519_0	1396141.BATP01000025_gene986	6.729e-169	539.0	COG0156@1|root,COG0156@2|Bacteria,46SSH@74201|Verrucomicrobia,2ITW1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_6633519_2	452637.Oter_2533	6.177e-40	153.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia,3K7P8@414999|Opitutae	414999|Opitutae	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
YHH3_k127_666502_0	583355.Caka_2613	3.406e-169	543.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia,3K7NE@414999|Opitutae	414999|Opitutae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
YHH3_k127_666502_1	583355.Caka_1376	2.38e-121	397.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46UY4@74201|Verrucomicrobia,3K7AN@414999|Opitutae	414999|Opitutae	K	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
YHH3_k127_666502_2	452637.Oter_2443	4.976e-95	321.0	COG1080@1|root,COG1080@2|Bacteria,46TX4@74201|Verrucomicrobia,3K7JG@414999|Opitutae	414999|Opitutae	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
YHH3_k127_668585_0	583355.Caka_0775	1.223e-167	539.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,3K7NF@414999|Opitutae	414999|Opitutae	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YHH3_k127_668585_2	1396141.BATP01000004_gene5901	2.815e-79	273.0	COG1179@1|root,COG1179@2|Bacteria,46THP@74201|Verrucomicrobia,2IU4H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiF family	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
YHH3_k127_668585_4	583355.Caka_1236	4.018e-76	266.0	COG1974@1|root,COG1974@2|Bacteria,46SU8@74201|Verrucomicrobia,3K8BT@414999|Opitutae	414999|Opitutae	K	Represses a number of genes involved in the response to DNA damage (SOS response)	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
YHH3_k127_668585_7	583355.Caka_2959	1.249e-55	201.0	COG0135@1|root,COG0135@2|Bacteria,46VS4@74201|Verrucomicrobia,3K840@414999|Opitutae	414999|Opitutae	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
YHH3_k127_668585_5	382464.ABSI01000021_gene425	1.01e-60	219.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia,2ITRR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Uroporphyrinogen-III synthase HemD	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
YHH3_k127_668585_3	382464.ABSI01000021_gene424	1.025e-77	269.0	COG0181@1|root,COG0181@2|Bacteria,46SWD@74201|Verrucomicrobia,2IU65@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Porphobilinogen deaminase, dipyromethane cofactor binding domain	-	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
YHH3_k127_668585_1	794903.OPIT5_30870	1.443e-159	508.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	414999|Opitutae	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
YHH3_k127_668585_6	794903.OPIT5_30880	5.445e-57	204.0	COG0440@1|root,COG0440@2|Bacteria,46SUP@74201|Verrucomicrobia,3K810@414999|Opitutae	414999|Opitutae	E	acetolactate synthase	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
YHH3_k127_6693046_2	583355.Caka_0684	3.799e-65	233.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia,3K7QQ@414999|Opitutae	414999|Opitutae	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YHH3_k127_6693046_4	583355.Caka_2351	5.416e-33	145.0	COG3307@1|root,COG3307@2|Bacteria,46XGV@74201|Verrucomicrobia,3K792@414999|Opitutae	414999|Opitutae	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH3_k127_6693046_0	452637.Oter_4082	5.112e-199	646.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,46UK0@74201|Verrucomicrobia,3K77D@414999|Opitutae	414999|Opitutae	P	E1-E2 ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,Hydrolase
YHH3_k127_6693046_3	452637.Oter_4081	7.123e-57	206.0	COG2836@1|root,COG2836@2|Bacteria,46VBD@74201|Verrucomicrobia,3K9GV@414999|Opitutae	414999|Opitutae	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
YHH3_k127_6693046_1	794903.OPIT5_02735	3.771e-179	573.0	COG0348@1|root,COG0348@2|Bacteria,46TZJ@74201|Verrucomicrobia,3K7F6@414999|Opitutae	414999|Opitutae	C	cytochrome c oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
YHH3_k127_6696990_0	583355.Caka_1954	9.251e-172	548.0	COG0766@1|root,COG0766@2|Bacteria,46U7P@74201|Verrucomicrobia,3K78X@414999|Opitutae	414999|Opitutae	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
YHH3_k127_6696990_1	382464.ABSI01000011_gene2694	6.406e-59	209.0	COG4508@1|root,COG4508@2|Bacteria,46VH7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
YHH3_k127_6696990_2	314278.NB231_04505	7.008e-47	171.0	COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH3_k127_6714674_2	66875.JODY01000002_gene5080	9.366e-07	52.0	COG1846@1|root,COG1846@2|Bacteria,2IHP0@201174|Actinobacteria	201174|Actinobacteria	K	marr family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
YHH3_k127_6714674_0	278957.ABEA03000197_gene423	1.483e-90	313.0	COG0845@1|root,COG0845@2|Bacteria,46U1B@74201|Verrucomicrobia,3K78A@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
YHH3_k127_6714674_1	338963.Pcar_2244	6.159e-67	231.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43S5E@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YHH3_k127_6730550_3	583355.Caka_0027	3.12e-47	179.0	COG2010@1|root,COG2010@2|Bacteria,46T74@74201|Verrucomicrobia,3K83Q@414999|Opitutae	414999|Opitutae	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YHH3_k127_6730550_0	382464.ABSI01000011_gene3056	1.844e-76	262.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
YHH3_k127_6730550_1	382464.ABSI01000005_gene1408	3.661e-71	244.0	COG0461@1|root,COG0461@2|Bacteria,46YZ3@74201|Verrucomicrobia,2IU4N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YHH3_k127_6730550_2	1118153.MOY_09127	4.394e-68	239.0	COG2138@1|root,COG2138@2|Bacteria,1R8AE@1224|Proteobacteria,1S06H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cobalamin (vitamin B12) biosynthesis CbiX	-	-	-	-	-	-	-	-	-	-	-	-	CbiX
YHH3_k127_6739818_0	452637.Oter_1542	4.046e-32	136.0	COG0697@1|root,COG0697@2|Bacteria,46SR7@74201|Verrucomicrobia	2|Bacteria	EG	EamA-like transporter family	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
YHH3_k127_6739818_1	1298593.TOL_3477	4.519e-07	63.0	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,1XRZ9@135619|Oceanospirillales	135619|Oceanospirillales	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YHH3_k127_6754198_0	1454007.JAUG01000063_gene269	2.018e-168	542.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1IVB2@117747|Sphingobacteriia	976|Bacteroidetes	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YHH3_k127_6773288_0	1501230.ET33_08340	2.728e-38	149.0	COG5018@1|root,COG5018@2|Bacteria,1VGWS@1239|Firmicutes,4HQT0@91061|Bacilli,26VQ3@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase III	exoN1	-	-	-	-	-	-	-	-	-	-	-	RNase_T
YHH3_k127_6773288_2	926554.KI912668_gene5136	7.697e-27	114.0	COG1487@1|root,COG1487@2|Bacteria,1WMSZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_6773288_1	697282.Mettu_1892	2.518e-32	127.0	COG2337@1|root,COG2337@2|Bacteria,1PVJ9@1224|Proteobacteria,1TM47@1236|Gammaproteobacteria,1XGTH@135618|Methylococcales	2|Bacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	chpA	GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
YHH3_k127_6828705_0	452637.Oter_2744	1.528e-99	333.0	COG1363@1|root,COG1363@2|Bacteria,46SM3@74201|Verrucomicrobia,3K7IQ@414999|Opitutae	414999|Opitutae	G	peptidase M42	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
YHH3_k127_6828705_1	452637.Oter_2745	9.013e-69	244.0	COG0106@1|root,COG0106@2|Bacteria,46SVR@74201|Verrucomicrobia,3K79Z@414999|Opitutae	414999|Opitutae	E	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YHH3_k127_6828705_2	1121396.KB893066_gene1580	2.251e-58	203.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,2MIUG@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_6857379_1	583355.Caka_0695	1.284e-163	522.0	COG0187@1|root,COG0187@2|Bacteria,46TW5@74201|Verrucomicrobia,3K7GR@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH3_k127_6857379_0	452637.Oter_0658	0.0	1072.0	COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia,3K74R@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH3_k127_6857379_2	583355.Caka_2125	1.034e-149	486.0	COG0569@1|root,COG0569@2|Bacteria,46TDR@74201|Verrucomicrobia	74201|Verrucomicrobia	C	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
YHH3_k127_6857379_3	382464.ABSI01000021_gene375	7.56e-144	471.0	COG0168@1|root,COG0168@2|Bacteria,46UGP@74201|Verrucomicrobia,2IVEG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
YHH3_k127_6857379_4	583355.Caka_2321	3.42e-99	334.0	COG1131@1|root,COG1131@2|Bacteria,46UAZ@74201|Verrucomicrobia,3K7S3@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_6857379_5	278957.ABEA03000094_gene4642	1.642e-59	215.0	COG1277@1|root,COG1277@2|Bacteria,46T0W@74201|Verrucomicrobia,3K7JF@414999|Opitutae	414999|Opitutae	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
YHH3_k127_6857379_6	794903.OPIT5_12795	3.572e-18	91.0	COG3225@1|root,COG3225@2|Bacteria,46SRK@74201|Verrucomicrobia,3K735@414999|Opitutae	414999|Opitutae	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
YHH3_k127_6862198_1	583355.Caka_3113	3.981e-38	156.0	COG1566@1|root,COG1566@2|Bacteria,46W72@74201|Verrucomicrobia	74201|Verrucomicrobia	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	-
YHH3_k127_6862198_0	583355.Caka_3112	1.882e-67	236.0	COG1285@1|root,COG1285@2|Bacteria,46VKA@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
YHH3_k127_6862198_2	583355.Caka_3111	3.724e-20	91.0	COG5036@1|root,COG5036@2|Bacteria,46VA7@74201|Verrucomicrobia	74201|Verrucomicrobia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
YHH3_k127_6878498_4	983545.Glaag_0207	4.599e-22	96.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,464X7@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Serine acetyltransferase, N-terminal	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
YHH3_k127_6878498_1	382464.ABSI01000011_gene3048	3.547e-86	292.0	COG0020@1|root,COG0020@2|Bacteria,46SMY@74201|Verrucomicrobia,2IU5V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
YHH3_k127_6878498_3	452637.Oter_1922	1.311e-37	152.0	COG4589@1|root,COG4589@2|Bacteria,46SX9@74201|Verrucomicrobia,3K7WK@414999|Opitutae	414999|Opitutae	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
YHH3_k127_6878498_0	452637.Oter_4632	2.963e-113	376.0	COG0743@1|root,COG0743@2|Bacteria,46S90@74201|Verrucomicrobia,3K7BM@414999|Opitutae	414999|Opitutae	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
YHH3_k127_6878498_2	382464.ABSI01000011_gene3051	1.472e-72	252.0	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,2ITH1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
YHH3_k127_6906942_6	583355.Caka_1969	1.11e-06	51.0	COG0730@1|root,COG0730@2|Bacteria,46VE4@74201|Verrucomicrobia,3K7RM@414999|Opitutae	414999|Opitutae	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YHH3_k127_6906942_2	278957.ABEA03000060_gene3152	2.297e-76	271.0	COG1195@1|root,COG1195@2|Bacteria,46UKV@74201|Verrucomicrobia,3K7K7@414999|Opitutae	414999|Opitutae	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
YHH3_k127_6906942_1	240016.ABIZ01000001_gene5950	9.1e-88	303.0	COG1104@1|root,COG1104@2|Bacteria,46SFF@74201|Verrucomicrobia,2IWK9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YHH3_k127_6906942_5	583355.Caka_1946	3.035e-51	191.0	COG1652@1|root,COG1652@2|Bacteria,46T8E@74201|Verrucomicrobia,3K82V@414999|Opitutae	414999|Opitutae	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
YHH3_k127_6906942_0	794903.OPIT5_05260	8.332e-118	390.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,46S8G@74201|Verrucomicrobia,3K7IY@414999|Opitutae	414999|Opitutae	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
YHH3_k127_6906942_4	1123070.KB899250_gene604	6.163e-53	192.0	COG0783@1|root,COG0783@2|Bacteria,46VAF@74201|Verrucomicrobia,2IUPW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
YHH3_k127_6906942_3	794903.OPIT5_07300	7.179e-64	228.0	COG4608@1|root,COG4608@2|Bacteria,46SHJ@74201|Verrucomicrobia,3K7GF@414999|Opitutae	414999|Opitutae	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
YHH3_k127_6925469_1	765913.ThidrDRAFT_1061	4.27e-21	104.0	COG2340@1|root,COG5549@1|root,COG2340@2|Bacteria,COG5549@2|Bacteria,1RJVF@1224|Proteobacteria,1SB6V@1236|Gammaproteobacteria,1X2BX@135613|Chromatiales	1236|Gammaproteobacteria	O	Domain of unknown function (DUF4214)	-	-	-	-	-	-	-	-	-	-	-	-	CAP,DUF4214
YHH3_k127_6925469_0	575540.Isop_0122	2.533e-88	299.0	COG1473@1|root,COG1473@2|Bacteria,2IY78@203682|Planctomycetes	203682|Planctomycetes	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YHH3_k127_6946981_2	583355.Caka_1842	3.662e-78	267.0	COG1208@1|root,COG1208@2|Bacteria,46UYH@74201|Verrucomicrobia,3K75K@414999|Opitutae	414999|Opitutae	JM	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
YHH3_k127_6946981_5	794903.OPIT5_03245	1.616e-19	94.0	COG5349@1|root,COG5349@2|Bacteria,46XVT@74201|Verrucomicrobia,3K8ER@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
YHH3_k127_6946981_3	278957.ABEA03000133_gene1585	2.936e-32	126.0	COG0254@1|root,COG0254@2|Bacteria,46XUU@74201|Verrucomicrobia,3K8B9@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL31 family	-	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
YHH3_k127_6946981_6	595494.Tola_0309	6.736e-17	80.0	COG0257@1|root,COG0257@2|Bacteria,1NGBJ@1224|Proteobacteria,1SCR7@1236|Gammaproteobacteria,1Y66Q@135624|Aeromonadales	135624|Aeromonadales	J	Belongs to the bacterial ribosomal protein bL36 family	-	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
YHH3_k127_6946981_1	452637.Oter_2556	1.598e-101	337.0	COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia,3K7US@414999|Opitutae	414999|Opitutae	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
YHH3_k127_6946981_0	240016.ABIZ01000001_gene4206	1.454e-216	704.0	COG0612@1|root,COG0612@2|Bacteria,46UTT@74201|Verrucomicrobia,2ITM2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH3_k127_6946981_4	583355.Caka_2996	4.083e-22	96.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia,3K7P8@414999|Opitutae	414999|Opitutae	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
YHH3_k127_6950247_8	452637.Oter_3946	1.462e-54	201.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01992,ko:K09690,ko:K09691,ko:K09692	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC2_membrane
YHH3_k127_6950247_3	452637.Oter_4012	1.192e-83	293.0	COG0438@1|root,COG0438@2|Bacteria,46V09@74201|Verrucomicrobia,3K7MD@414999|Opitutae	414999|Opitutae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YHH3_k127_6950247_13	583355.Caka_1124	1.042e-09	68.0	2AXAP@1|root,31P9S@2|Bacteria,46XVW@74201|Verrucomicrobia,3K8EZ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6950247_9	1437425.CSEC_1696	9.368e-21	94.0	COG2331@1|root,COG2331@2|Bacteria,2JH9F@204428|Chlamydiae	204428|Chlamydiae	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH3_k127_6950247_12	583355.Caka_1125	7.236e-12	74.0	2A1DB@1|root,30PKC@2|Bacteria,46WF1@74201|Verrucomicrobia,3K8HN@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
YHH3_k127_6950247_1	583355.Caka_1126	7.331e-90	304.0	COG0142@1|root,COG0142@2|Bacteria,46S62@74201|Verrucomicrobia,3K7Y1@414999|Opitutae	414999|Opitutae	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH3_k127_6950247_6	583355.Caka_2980	3.718e-75	261.0	COG0740@1|root,COG0740@2|Bacteria,46TSB@74201|Verrucomicrobia,3K79J@414999|Opitutae	414999|Opitutae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YHH3_k127_6950247_7	583355.Caka_0843	5.538e-55	198.0	COG0290@1|root,COG0290@2|Bacteria,46V47@74201|Verrucomicrobia,3K841@414999|Opitutae	414999|Opitutae	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
YHH3_k127_6950247_5	583355.Caka_0842	9.097e-77	268.0	COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia,3K7YX@414999|Opitutae	414999|Opitutae	M	cell wall hydrolase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
YHH3_k127_6950247_11	1227457.C451_17380	2.336e-12	74.0	COG0239@1|root,arCOG04701@2157|Archaea,2XXXU@28890|Euryarchaeota,23W6A@183963|Halobacteria	183963|Halobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB2	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
YHH3_k127_6950247_10	493475.GARC_1321	5.438e-19	91.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,467ZU@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
YHH3_k127_6950247_2	794903.OPIT5_02105	1.335e-88	314.0	COG0457@1|root,COG0457@2|Bacteria,46SRS@74201|Verrucomicrobia,3K7VK@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6950247_0	583355.Caka_2205	1.121e-300	952.0	COG0022@1|root,COG0508@1|root,COG1071@1|root,COG0022@2|Bacteria,COG0508@2|Bacteria,COG1071@2|Bacteria,46TPF@74201|Verrucomicrobia,3K7MS@414999|Opitutae	414999|Opitutae	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
YHH3_k127_6950247_15	1292035.H476_1252	3.105e-06	54.0	COG1396@1|root,COG1396@2|Bacteria,1VMDD@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
YHH3_k127_6950247_4	1384056.N787_02590	2.495e-82	282.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1XAD0@135614|Xanthomonadales	135614|Xanthomonadales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YHH3_k127_6950247_14	1121382.JQKG01000022_gene1455	1.973e-08	63.0	COG3979@1|root,COG3979@2|Bacteria	2|Bacteria	S	chitin catabolic process	csn	-	3.2.1.132	ko:K01233	ko00520,ko01100,map00520,map01100	-	R02833	-	ko00000,ko00001,ko01000	-	-	-	Alginate_lyase,Glyco_hydro_46
YHH3_k127_695300_0	583355.Caka_0983	5.814e-304	944.0	COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
YHH3_k127_6964967_1	583355.Caka_1789	9.463e-53	198.0	COG0248@1|root,COG0248@2|Bacteria,46T7T@74201|Verrucomicrobia,3K7WZ@414999|Opitutae	414999|Opitutae	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
YHH3_k127_6964967_0	382464.ABSI01000023_gene570	3.884e-70	244.0	COG0313@1|root,COG0313@2|Bacteria,46SVC@74201|Verrucomicrobia,2IU7K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YHH3_k127_6964967_2	378806.STAUR_0949	5.583e-42	158.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria,2YV8R@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
YHH3_k127_6970462_4	382464.ABSI01000011_gene2590	5.372e-11	66.0	COG4773@1|root,COG4773@2|Bacteria,46TH4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_6970462_2	278957.ABEA03000144_gene3995	4.691e-51	197.0	COG1609@1|root,COG1609@2|Bacteria,46V6P@74201|Verrucomicrobia,3K8MC@414999|Opitutae	414999|Opitutae	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
YHH3_k127_6970462_0	991.IW20_18470	3.737e-118	396.0	COG3119@1|root,COG3119@2|Bacteria,4NE7S@976|Bacteroidetes,1I2RA@117743|Flavobacteriia,2NVTT@237|Flavobacterium	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_6970462_3	1415779.JOMH01000001_gene2200	2.581e-38	146.0	COG1396@1|root,COG1396@2|Bacteria,1QUPK@1224|Proteobacteria,1T4CG@1236|Gammaproteobacteria,1XBJA@135614|Xanthomonadales	135614|Xanthomonadales	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6970462_1	1454004.AW11_00062	1.208e-60	210.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2VMN6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HipA domain protein	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
YHH3_k127_6974945_4	583355.Caka_2308	2.352e-24	104.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46USH@74201|Verrucomicrobia,3K738@414999|Opitutae	414999|Opitutae	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
YHH3_k127_6974945_1	118168.MC7420_5234	5.637e-70	255.0	COG5563@1|root,COG5563@2|Bacteria,1GIA8@1117|Cyanobacteria,1HFHC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6974945_3	583355.Caka_2147	1.061e-25	113.0	COG0272@1|root,COG0272@2|Bacteria,46WS4@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6974945_0	583355.Caka_2146	4.798e-74	259.0	28MB4@1|root,2ZAPN@2|Bacteria	2|Bacteria	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
YHH3_k127_6974945_2	1123070.KB899265_gene1847	1.583e-26	119.0	COG0829@1|root,COG0829@2|Bacteria,46T2F@74201|Verrucomicrobia,2IUSK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	UreD urease accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	UreD
YHH3_k127_6974945_5	109871.XP_006683462.1	0.0007745	42.0	COG0378@1|root,2QR6E@2759|Eukaryota,38GQT@33154|Opisthokonta,3NV6U@4751|Fungi	4751|Fungi	KO	Urease accessory protein	-	GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0044237,GO:0044281,GO:0071704,GO:0071941,GO:1901564	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
YHH3_k127_6984050_0	1403819.BATR01000114_gene3915	5.737e-87	292.0	COG0399@1|root,COG0399@2|Bacteria,46SEI@74201|Verrucomicrobia,2ITTP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YHH3_k127_6984050_1	583355.Caka_1875	7.135e-44	173.0	COG4948@1|root,COG4948@2|Bacteria,46VQT@74201|Verrucomicrobia,3K7YV@414999|Opitutae	414999|Opitutae	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C
YHH3_k127_6984050_2	452637.Oter_2807	6.915e-40	161.0	COG0318@1|root,COG0318@2|Bacteria,46V2U@74201|Verrucomicrobia,3K7ZY@414999|Opitutae	414999|Opitutae	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
YHH3_k127_702440_6	1209072.ALBT01000058_gene831	2.288e-47	174.0	COG0834@1|root,COG0834@2|Bacteria,1REKB@1224|Proteobacteria,1S5DG@1236|Gammaproteobacteria,1FHXK@10|Cellvibrio	1236|Gammaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
YHH3_k127_702440_2	1121405.dsmv_2056	3.735e-92	319.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,42Q4T@68525|delta/epsilon subdivisions,2WK9F@28221|Deltaproteobacteria,2MHXS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_702440_3	1121405.dsmv_2057	1.917e-91	305.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42PYJ@68525|delta/epsilon subdivisions,2WKHY@28221|Deltaproteobacteria,2MJ28@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_702440_0	1232437.KL661988_gene228	1.105e-107	369.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42N3Y@68525|delta/epsilon subdivisions,2WJFS@28221|Deltaproteobacteria,2MJEA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_702440_1	1265505.ATUG01000001_gene4787	2.98e-103	349.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42QGA@68525|delta/epsilon subdivisions,2WJYS@28221|Deltaproteobacteria,2MI4W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_702440_4	1121405.dsmv_2060	9.363e-84	285.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,42MIS@68525|delta/epsilon subdivisions,2WMK7@28221|Deltaproteobacteria,2MJNM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
YHH3_k127_702440_5	926549.KI421517_gene3331	1.491e-66	235.0	COG3828@1|root,COG3828@2|Bacteria,4NJ6A@976|Bacteroidetes,47PB3@768503|Cytophagia	976|Bacteroidetes	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
YHH3_k127_702440_7	452637.Oter_3207	3.214e-06	49.0	COG3507@1|root,COG3507@2|Bacteria,46TWN@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
YHH3_k127_7025987_5	748247.AZKH_2786	5.645e-24	106.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ3A@28216|Betaproteobacteria,2KZ1U@206389|Rhodocyclales	206389|Rhodocyclales	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YHH3_k127_7025987_3	583355.Caka_3007	1.235e-49	182.0	COG0335@1|root,COG0335@2|Bacteria,46T0S@74201|Verrucomicrobia,3K87M@414999|Opitutae	414999|Opitutae	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
YHH3_k127_7025987_0	452637.Oter_3100	3.396e-86	291.0	COG0336@1|root,COG0336@2|Bacteria,46TWF@74201|Verrucomicrobia,3K79N@414999|Opitutae	414999|Opitutae	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
YHH3_k127_7025987_4	382464.ABSI01000002_gene4278	6.074e-27	112.0	COG0228@1|root,COG0228@2|Bacteria,46WC2@74201|Verrucomicrobia,2IUP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S16	-	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
YHH3_k127_7025987_1	583355.Caka_1858	1.436e-67	237.0	COG1212@1|root,COG1212@2|Bacteria,46SS4@74201|Verrucomicrobia,3K7GX@414999|Opitutae	414999|Opitutae	M	Cytidylyltransferase	-	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
YHH3_k127_7025987_2	324925.Ppha_0327	1.043e-66	232.0	COG0551@1|root,COG0551@2|Bacteria,1FF54@1090|Chlorobi	1090|Chlorobi	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7025987_6	452637.Oter_3582	2.022e-13	72.0	COG2159@1|root,COG2159@2|Bacteria,46VK5@74201|Verrucomicrobia,3K854@414999|Opitutae	414999|Opitutae	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
YHH3_k127_7032151_5	317619.ANKN01000013_gene3519	9.115e-38	147.0	COG0259@1|root,COG0259@2|Bacteria,1G0HC@1117|Cyanobacteria,1MMBB@1212|Prochloraceae	1117|Cyanobacteria	F	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
YHH3_k127_7032151_1	583355.Caka_2953	1.826e-99	335.0	COG1968@1|root,COG1968@2|Bacteria,46SP6@74201|Verrucomicrobia,3K7D8@414999|Opitutae	414999|Opitutae	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
YHH3_k127_7032151_3	794903.OPIT5_11015	1.623e-56	206.0	COG0600@1|root,COG0600@2|Bacteria,46Y5C@74201|Verrucomicrobia,3K8YK@414999|Opitutae	414999|Opitutae	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
YHH3_k127_7032151_2	452637.Oter_3561	4.376e-71	248.0	COG1116@1|root,COG1116@2|Bacteria,46YT1@74201|Verrucomicrobia,3K8NJ@414999|Opitutae	414999|Opitutae	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
YHH3_k127_7032151_0	583355.Caka_2998	1.871e-227	723.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia,3K7GD@414999|Opitutae	414999|Opitutae	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
YHH3_k127_7032151_4	278957.ABEA03000135_gene1764	2.756e-46	177.0	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,3K73Q@414999|Opitutae	414999|Opitutae	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
YHH3_k127_7044243_1	1379270.AUXF01000005_gene406	1.325e-98	339.0	COG1232@1|root,COG1232@2|Bacteria,1ZUZT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
YHH3_k127_7044243_0	583355.Caka_2769	5.071e-151	490.0	COG0635@1|root,COG0635@2|Bacteria,46TQX@74201|Verrucomicrobia,3K7DD@414999|Opitutae	414999|Opitutae	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
YHH3_k127_7070177_0	382464.ABSI01000006_gene842	0.0	1322.0	COG0841@1|root,COG0841@2|Bacteria,46U7C@74201|Verrucomicrobia,2IVDR@203494|Verrucomicrobiae	2|Bacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_7070177_1	1121396.KB893066_gene1579	4.814e-27	114.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,2MHPS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH3_k127_7077050_0	340177.Cag_1408	2.157e-118	397.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02004,ko:K07798	ko02020,map02020	M00258	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.1.4,3.A.1,8.A.1	-	-	FtsX,HlyD_3,HlyD_D23,MacB_PCD
YHH3_k127_7077050_1	717773.Thicy_0352	1.245e-11	66.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,1RRTY@1236|Gammaproteobacteria,4603C@72273|Thiotrichales	72273|Thiotrichales	M	Peptidase M50	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	HlyD_3,HlyD_D23
YHH3_k127_7081436_1	649638.Trad_2705	7.92e-27	115.0	COG0382@1|root,COG0546@1|root,COG0382@2|Bacteria,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,UbiA
YHH3_k127_7081436_0	335543.Sfum_2336	5.045e-174	550.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,43DIW@68525|delta/epsilon subdivisions,2X8Q7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
YHH3_k127_7083352_2	583355.Caka_1734	8.349e-34	136.0	COG3216@1|root,COG3216@2|Bacteria,46WES@74201|Verrucomicrobia,3K9VH@414999|Opitutae	414999|Opitutae	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
YHH3_k127_7083352_0	382464.ABSI01000013_gene1816	6.716e-144	469.0	COG3876@1|root,COG3876@2|Bacteria,46UR1@74201|Verrucomicrobia,2IV8D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
YHH3_k127_7083352_1	373903.Hore_02670	1.489e-116	391.0	COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes	1239|Firmicutes	G	PFAM glycoside hydrolase, family 16	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_16
YHH3_k127_7083956_0	583355.Caka_0417	5.776e-190	610.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46TZV@74201|Verrucomicrobia,3K897@414999|Opitutae	414999|Opitutae	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
YHH3_k127_7083956_2	404589.Anae109_0898	7.307e-67	241.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,42PXX@68525|delta/epsilon subdivisions,2WIMB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Transport permease protein	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
YHH3_k127_7083956_1	404589.Anae109_0897	1.127e-83	288.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,42MWS@68525|delta/epsilon subdivisions,2WMMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	yadG	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_7083956_3	74547.PMT_1578	1.286e-22	103.0	COG0116@1|root,COG0116@2|Bacteria,1G03K@1117|Cyanobacteria,1MKNW@1212|Prochloraceae	1117|Cyanobacteria	L	Belongs to the methyltransferase superfamily	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
YHH3_k127_7085637_2	926556.Echvi_0925	2.976e-16	81.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,47TYC@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_7085637_0	743722.Sph21_0983	9.66e-108	363.0	COG1454@1|root,COG1454@2|Bacteria,4NE5Y@976|Bacteroidetes,1IRQQ@117747|Sphingobacteriia	976|Bacteroidetes	C	alcohol dehydrogenase	-	-	1.1.1.61	ko:K18120,ko:K19954	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R01644	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
YHH3_k127_7085637_1	331113.SNE_A15450	3.194e-71	251.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.1.2.28,4.3.3.7	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01782,R10147	RC00307,RC00572,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YHH3_k127_7133791_1	452637.Oter_3616	2.656e-124	404.0	COG3842@1|root,COG3842@2|Bacteria,46SFH@74201|Verrucomicrobia,3K7SS@414999|Opitutae	414999|Opitutae	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran
YHH3_k127_7133791_0	583355.Caka_1479	4.809e-165	526.0	COG0208@1|root,COG0208@2|Bacteria,46SMW@74201|Verrucomicrobia,3K7VI@414999|Opitutae	414999|Opitutae	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
YHH3_k127_7137667_1	583355.Caka_0208	5.075e-123	404.0	COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia,3K7KP@414999|Opitutae	414999|Opitutae	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
YHH3_k127_7137667_0	583355.Caka_0854	4.972e-167	535.0	COG2804@1|root,COG2804@2|Bacteria,46XYI@74201|Verrucomicrobia,3K8MN@414999|Opitutae	414999|Opitutae	NU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
YHH3_k127_7143829_1	583355.Caka_1197	5.343e-112	372.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,3K7QD@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YHH3_k127_7143829_0	583355.Caka_1198	1.278e-158	514.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia,3K788@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
YHH3_k127_7143829_3	583355.Caka_1153	2.504e-10	69.0	COG1214@1|root,COG1214@2|Bacteria,46WS7@74201|Verrucomicrobia,3K8JH@414999|Opitutae	414999|Opitutae	O	PFAM Peptidase M22, glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
YHH3_k127_7143829_2	452637.Oter_2737	2.246e-27	115.0	COG0787@1|root,COG0787@2|Bacteria,46UBN@74201|Verrucomicrobia,3K796@414999|Opitutae	414999|Opitutae	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
YHH3_k127_7150913_1	278957.ABEA03000060_gene3065	1.625e-72	251.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,46S5K@74201|Verrucomicrobia,3K7D9@414999|Opitutae	414999|Opitutae	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
YHH3_k127_7150913_0	452637.Oter_3688	4.789e-213	668.0	COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,3K78I@414999|Opitutae	414999|Opitutae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
YHH3_k127_7150913_2	478801.Ksed_16430	1.176e-13	73.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,1ZVF2@145357|Dermacoccaceae	201174|Actinobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
YHH3_k127_7159948_1	583355.Caka_1345	1.179e-133	443.0	COG1204@1|root,COG1204@2|Bacteria,46SCW@74201|Verrucomicrobia,3K8N5@414999|Opitutae	414999|Opitutae	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
YHH3_k127_7159948_2	1294143.H681_04625	1.71e-50	191.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Peptidyl-prolyl cis-trans	fklB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005527,GO:0005528,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042597,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:0140096,GO:1901363,GO:1901564	5.2.1.8	ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
YHH3_k127_7159948_0	179408.Osc7112_4664	8.134e-237	740.0	COG0493@1|root,COG0493@2|Bacteria,1G0SD@1117|Cyanobacteria,1H8CN@1150|Oscillatoriales	1117|Cyanobacteria	E	TIGRFAM glutamate synthases, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD	Fer4_20,Pyr_redox_2
YHH3_k127_7159948_3	1121346.KB899827_gene480	6.228e-08	54.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,26RAZ@186822|Paenibacillaceae	91061|Bacilli	E	Glutamate synthase	gltA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
YHH3_k127_7187092_3	932213.SPM24T3_18226	1.696e-06	52.0	COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,1RNBC@1236|Gammaproteobacteria,401HH@613|Serratia	1236|Gammaproteobacteria	U	With GsiABD is involved in the transport of glutathione into the cell	gsiD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K13891	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	iECABU_c1320.ECABU_c08730,iECP_1309.ECP_0846,ic_1306.c0917	BPD_transp_1,OppC_N
YHH3_k127_7187092_2	1121033.AUCF01000004_gene4998	1.68e-59	220.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,2JPDK@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K12369	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
YHH3_k127_7187092_1	382464.ABSI01000011_gene2739	1.806e-167	541.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	dppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YHH3_k127_7187092_0	794903.OPIT5_06520	1.399e-197	623.0	COG0205@1|root,COG0205@2|Bacteria,46SFN@74201|Verrucomicrobia,3K7HI@414999|Opitutae	414999|Opitutae	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
YHH3_k127_7187092_4	760154.Sulba_2154	0.000134	44.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,42QPT@68525|delta/epsilon subdivisions,2YN0Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm tigr00688	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
YHH3_k127_7195583_1	278957.ABEA03000093_gene4635	1.059e-59	213.0	arCOG03330@1|root,2Z82Q@2|Bacteria	2|Bacteria	S	PFAM Methanol-cobalamin methyltransferase B subunit	-	-	2.1.1.90	ko:K04480	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R04384,R09098	RC00035,RC01144,RC01145,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	MtaB
YHH3_k127_7195583_0	452637.Oter_3658	1.102e-75	259.0	COG5012@1|root,COG5012@2|Bacteria,46V56@74201|Verrucomicrobia,3K7ZT@414999|Opitutae	414999|Opitutae	S	Methionine synthase B12-binding module cap domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
YHH3_k127_7292933_0	349741.Amuc_0806	2.881e-82	287.0	COG0168@1|root,COG0168@2|Bacteria,46U92@74201|Verrucomicrobia,2IVH0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
YHH3_k127_7292933_1	1396418.BATQ01000149_gene2218	1.561e-42	164.0	COG0569@1|root,COG0569@2|Bacteria,46W0A@74201|Verrucomicrobia,2IUXU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
YHH3_k127_7331994_2	382464.ABSI01000013_gene1571	3.285e-20	96.0	COG1572@1|root,COG3210@1|root,COG3386@1|root,COG4257@1|root,COG5373@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG4257@2|Bacteria,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	-	-	-	ko:K13277,ko:K15125,ko:K15539	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000,ko01002,ko03110	-	-	-	DUF5011
YHH3_k127_7331994_3	767817.Desgi_2853	1.923e-06	54.0	2EEX1@1|root,338QB@2|Bacteria,1VGA4@1239|Firmicutes,24UMM@186801|Clostridia,26355@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
YHH3_k127_7331994_1	382464.ABSI01000013_gene1572	1.999e-44	165.0	COG0664@1|root,COG0664@2|Bacteria,46X6S@74201|Verrucomicrobia,2IURE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
YHH3_k127_7331994_0	382464.ABSI01000013_gene1573	8.825e-285	885.0	COG2066@1|root,COG2905@1|root,COG2066@2|Bacteria,COG2905@2|Bacteria,46USD@74201|Verrucomicrobia,2ITM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	ET	Glutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Glutaminase,cNMP_binding
YHH3_k127_7337999_2	1396141.BATP01000048_gene3522	3.006e-25	105.0	COG0266@1|root,COG0266@2|Bacteria,46SKI@74201|Verrucomicrobia,2IURK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	-	-	-	-	-	-	-	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
YHH3_k127_7337999_0	1550091.JROE01000004_gene1456	1.33e-124	411.0	COG0613@1|root,COG0613@2|Bacteria,4NHZ5@976|Bacteroidetes,1ISEJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001
YHH3_k127_7337999_1	1121937.AUHJ01000004_gene1054	2.206e-33	136.0	COG2930@1|root,COG2930@2|Bacteria,1RCYH@1224|Proteobacteria,1S41U@1236|Gammaproteobacteria,46AZS@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Las17-binding protein actin regulator	CT2216	-	-	-	-	-	-	-	-	-	-	-	Ysc84
YHH3_k127_7341308_1	794903.OPIT5_01475	1.98e-76	263.0	COG4284@1|root,COG4284@2|Bacteria,46U9U@74201|Verrucomicrobia,3K7T1@414999|Opitutae	414999|Opitutae	G	UTP--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.23,2.7.7.64,2.7.7.83	ko:K00972,ko:K12447	ko00040,ko00052,ko00053,ko00520,ko01100,ko01130,map00040,map00052,map00053,map00520,map01100,map01130	M00014,M00361,M00362	R00289,R00416,R00502,R01381,R03077,R08845	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
YHH3_k127_7341308_2	583355.Caka_1910	1.398e-13	74.0	COG2919@1|root,COG2919@2|Bacteria,46XW4@74201|Verrucomicrobia,3K8FZ@414999|Opitutae	414999|Opitutae	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
YHH3_k127_7341308_0	382464.ABSI01000005_gene1025	1.105e-101	338.0	COG3267@1|root,COG3267@2|Bacteria,46XMZ@74201|Verrucomicrobia,2IW82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
YHH3_k127_740613_7	1121939.L861_22675	5.33e-17	83.0	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,1RMJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YHH3_k127_740613_2	1121939.L861_22680	2.42e-72	252.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1XJ7N@135619|Oceanospirillales	1236|Gammaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
YHH3_k127_740613_1	382464.ABSI01000023_gene585	6.03e-149	483.0	COG0621@1|root,COG0621@2|Bacteria,46S6B@74201|Verrucomicrobia,2ITRH@203494|Verrucomicrobiae	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
YHH3_k127_740613_6	1415756.JQMY01000001_gene1307	1.003e-20	102.0	COG2374@1|root,COG2374@2|Bacteria,1QXVK@1224|Proteobacteria,2TXVT@28211|Alphaproteobacteria,2PFZC@252301|Oceanicola	28211|Alphaproteobacteria	L	Endonuclease Exonuclease Phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos
YHH3_k127_740613_8	497964.CfE428DRAFT_3323	1.735e-09	65.0	COG2165@1|root,COG2165@2|Bacteria,46T3S@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YHH3_k127_740613_3	452637.Oter_2046	3.184e-43	169.0	COG0466@1|root,COG0466@2|Bacteria,46WE2@74201|Verrucomicrobia,3K9NW@414999|Opitutae	414999|Opitutae	O	PFAM peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
YHH3_k127_740613_0	583355.Caka_1083	3.024e-278	868.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia,3K7JR@414999|Opitutae	414999|Opitutae	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YHH3_k127_740613_4	278957.ABEA03000180_gene2017	2.23e-33	131.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,3K8AV@414999|Opitutae	414999|Opitutae	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YHH3_k127_740613_9	889378.Spiaf_0199	6.579e-08	54.0	COG0459@1|root,COG0459@2|Bacteria,2J5CK@203691|Spirochaetes	203691|Spirochaetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YHH3_k127_7420970_4	452637.Oter_1299	1.008e-93	314.0	COG0039@1|root,COG0039@2|Bacteria,46T5I@74201|Verrucomicrobia,3K79S@414999|Opitutae	414999|Opitutae	C	Belongs to the LDH MDH superfamily	-	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
YHH3_k127_7420970_2	794903.OPIT5_04235	2.101e-125	412.0	COG0235@1|root,COG0235@2|Bacteria,46UR3@74201|Verrucomicrobia,3K7W3@414999|Opitutae	414999|Opitutae	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
YHH3_k127_7420970_9	278957.ABEA03000086_gene2503	1.421e-22	101.0	COG4576@1|root,COG4576@2|Bacteria,46WMY@74201|Verrucomicrobia,3K8EE@414999|Opitutae	414999|Opitutae	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
YHH3_k127_7420970_10	1123242.JH636435_gene1239	4.013e-19	89.0	COG4576@1|root,COG4576@2|Bacteria,2J0UQ@203682|Planctomycetes	203682|Planctomycetes	CQ	PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
YHH3_k127_7420970_0	452637.Oter_1295	1.38e-177	568.0	COG1012@1|root,COG1012@2|Bacteria,46UYV@74201|Verrucomicrobia,3K7HF@414999|Opitutae	414999|Opitutae	C	Aldehyde dehydrogenase family	-	-	-	ko:K04021	ko00620,ko01100,ko01120,map00620,map01100,map01120	-	R00228	RC00004,RC01195	ko00000,ko00001	-	-	-	Aldedh
YHH3_k127_7420970_5	794903.OPIT5_04215	2.643e-41	154.0	COG4576@1|root,COG4576@2|Bacteria,46VMK@74201|Verrucomicrobia,3K8BF@414999|Opitutae	414999|Opitutae	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
YHH3_k127_7420970_8	452637.Oter_1293	4.248e-30	122.0	COG4577@1|root,COG4577@2|Bacteria,46W1J@74201|Verrucomicrobia,3K8AE@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
YHH3_k127_7420970_1	382464.ABSI01000020_gene268	3.287e-146	474.0	COG0282@1|root,COG0282@2|Bacteria,46SKB@74201|Verrucomicrobia,2ITSN@203494|Verrucomicrobiae	2|Bacteria	C	Acetokinase family	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1,2.7.2.15	ko:K00925,ko:K19697	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
YHH3_k127_7420970_6	382464.ABSI01000020_gene267	1.022e-34	134.0	COG4577@1|root,COG4577@2|Bacteria,46WBA@74201|Verrucomicrobia	74201|Verrucomicrobia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
YHH3_k127_7420970_7	794903.OPIT5_04195	2.829e-33	130.0	COG4577@1|root,COG4577@2|Bacteria,46W7U@74201|Verrucomicrobia,3K8C2@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
YHH3_k127_7420970_3	278957.ABEA03000087_gene601	2.176e-103	340.0	COG4869@1|root,COG4869@2|Bacteria,46UMP@74201|Verrucomicrobia,3K7FS@414999|Opitutae	414999|Opitutae	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
YHH3_k127_7420970_11	583355.Caka_1594	2.602e-06	49.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46W2M@74201|Verrucomicrobia,3K81K@414999|Opitutae	2|Bacteria	KLT	Sulfatase-modifying factor enzyme 1	egtB	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
YHH3_k127_7425060_1	1396141.BATP01000056_gene3264	5.104e-72	249.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,2IUI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_7425060_0	794903.OPIT5_22365	1.025e-111	377.0	COG4191@1|root,COG4585@1|root,COG4191@2|Bacteria,COG4585@2|Bacteria,46XZQ@74201|Verrucomicrobia,3K8PF@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
YHH3_k127_7427201_0	1122176.KB903533_gene2443	8.741e-201	632.0	COG0673@1|root,COG0673@2|Bacteria,4NIF1@976|Bacteroidetes,1IVYW@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_7427201_1	382464.ABSI01000010_gene3335	4.626e-68	239.0	COG1075@1|root,COG1075@2|Bacteria,46XK0@74201|Verrucomicrobia,2IW41@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7445097_1	742727.HMPREF9447_03311	9.446e-35	145.0	COG3534@1|root,COG3534@2|Bacteria,4PBFW@976|Bacteroidetes,2FZ0G@200643|Bacteroidia,4AUKA@815|Bacteroidaceae	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7445097_0	1288963.ADIS_1161	7.808e-83	284.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47XEA@768503|Cytophagia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_7468900_0	583355.Caka_2703	3.695e-107	349.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,3K7E9@414999|Opitutae	414999|Opitutae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH3_k127_7468900_4	1219031.BBJR01000056_gene1979	0.0005208	49.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,4ADYK@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YHH3_k127_7468900_2	452637.Oter_0242	2.288e-61	221.0	COG0811@1|root,COG0811@2|Bacteria,46SUA@74201|Verrucomicrobia,3K7EH@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH3_k127_7468900_1	583355.Caka_2442	3.766e-106	373.0	COG1729@1|root,COG1729@2|Bacteria,46TWU@74201|Verrucomicrobia,3K7AZ@414999|Opitutae	414999|Opitutae	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
YHH3_k127_74902_0	439235.Dalk_1474	4.181e-315	1008.0	COG0823@1|root,COG0823@2|Bacteria,1PFY8@1224|Proteobacteria,437BT@68525|delta/epsilon subdivisions,2WURP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_74902_3	439235.Dalk_1473	6.25e-25	116.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.1,2.8.1.2	ko:K00406,ko:K01011	ko00190,ko00270,ko00920,ko01100,ko01120,ko02020,ko04122,map00190,map00270,map00920,map01100,map01120,map02020,map04122	M00156	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrome_CBB3,PALP,Rhodanese
YHH3_k127_74902_4	1396141.BATP01000019_gene1681	0.0003972	53.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K19231	-	-	-	-	ko00000,ko02000	1.B.12	-	-	ESPR,PATR
YHH3_k127_74902_2	1492922.GY26_09390	1.314e-54	195.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1J67K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
YHH3_k127_74902_1	1122180.Lokhon_00496	1.062e-57	204.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,2U595@28211|Alphaproteobacteria,2P8VB@245186|Loktanella	28211|Alphaproteobacteria	T	GAF domain	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
YHH3_k127_7495253_0	383372.Rcas_3648	3.299e-142	473.0	COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,2G9DX@200795|Chloroflexi,377P0@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_7495253_2	696747.NIES39_H00400	1.039e-31	139.0	COG0438@1|root,COG0500@1|root,COG1196@1|root,COG1216@1|root,COG3401@1|root,COG3551@1|root,COG0438@2|Bacteria,COG0500@2|Bacteria,COG1196@2|Bacteria,COG1216@2|Bacteria,COG3401@2|Bacteria,COG3551@2|Bacteria,1FZUY@1117|Cyanobacteria,1H86A@1150|Oscillatoriales	1117|Cyanobacteria	DM	Glycosyl transferase, group	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Methyltransf_23,Methyltransf_31,Sulfotransfer_3
YHH3_k127_7495253_1	1144312.PMI09_00555	3.811e-120	402.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,2TU3M@28211|Alphaproteobacteria,4BBEB@82115|Rhizobiaceae	28211|Alphaproteobacteria	GM	ATP-binding protein	wzt	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
YHH3_k127_7495350_0	583355.Caka_2810	2.374e-67	230.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia,3K7KT@414999|Opitutae	414999|Opitutae	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
YHH3_k127_7495350_1	583355.Caka_0752	1.4e-42	161.0	COG4747@1|root,COG4747@2|Bacteria,46SXP@74201|Verrucomicrobia,3K816@414999|Opitutae	414999|Opitutae	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7495350_2	583355.Caka_2122	2.535e-40	151.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,3K8AH@414999|Opitutae	414999|Opitutae	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
YHH3_k127_7495350_3	382464.ABSI01000002_gene4276	3.74e-34	143.0	COG0705@1|root,COG0705@2|Bacteria,46W15@74201|Verrucomicrobia,2IUFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YHH3_k127_7507041_7	583355.Caka_1070	4.003e-16	79.0	COG1692@1|root,COG1692@2|Bacteria,46SQ2@74201|Verrucomicrobia,3K7NP@414999|Opitutae	414999|Opitutae	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
YHH3_k127_7507041_3	278957.ABEA03000157_gene635	6.582e-87	292.0	COG0036@1|root,COG0036@2|Bacteria,46TEK@74201|Verrucomicrobia,3K7FI@414999|Opitutae	414999|Opitutae	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YHH3_k127_7507041_4	452637.Oter_3602	2.994e-69	248.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,3K7IV@414999|Opitutae	414999|Opitutae	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_6
YHH3_k127_7507041_0	382464.ABSI01000010_gene3377	1.139e-125	411.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia,2ITMR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
YHH3_k127_7507041_1	382464.ABSI01000010_gene3376	3.835e-106	355.0	COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia,2ITU1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
YHH3_k127_7507041_5	583355.Caka_2951	2.938e-21	94.0	COG0333@1|root,COG0333@2|Bacteria,46WWH@74201|Verrucomicrobia,3K8FQ@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
YHH3_k127_7507041_6	794903.OPIT5_05340	6.766e-19	96.0	2F739@1|root,33ZIU@2|Bacteria,46VU4@74201|Verrucomicrobia,3K808@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7507041_2	452637.Oter_1623	8.41e-97	321.0	COG0082@1|root,COG0082@2|Bacteria,46SEA@74201|Verrucomicrobia,3K7DA@414999|Opitutae	414999|Opitutae	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
YHH3_k127_7517380_0	555088.DealDRAFT_1200	6.261e-39	164.0	COG0726@1|root,COG2273@1|root,COG0726@2|Bacteria,COG2273@2|Bacteria,1V6DN@1239|Firmicutes,24JSE@186801|Clostridia	186801|Clostridia	G	xylanase chitin deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
YHH3_k127_7517640_2	1123368.AUIS01000022_gene1018	7.054e-26	107.0	COG3450@1|root,COG3450@2|Bacteria,1N4VS@1224|Proteobacteria,1SC4C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ethanolamine utilisation protein EutQ	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
YHH3_k127_7517640_0	1123393.KB891316_gene1448	9.75e-135	438.0	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,2W92X@28216|Betaproteobacteria,1KS0Y@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_7517640_1	1123392.AQWL01000005_gene2880	5.729e-63	219.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.2.1.4	ko:K01179,ko:K21449	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40.2	GH5,GH9	-	DUF1929,Laminin_G_3,Metallophos
YHH3_k127_7523961_0	382464.ABSI01000010_gene3555	6.968e-234	730.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
YHH3_k127_7523961_1	926556.Echvi_1286	1.418e-88	295.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,47QAY@768503|Cytophagia	976|Bacteroidetes	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YHH3_k127_7530706_2	382464.ABSI01000010_gene3409	7.629e-47	179.0	COG0805@1|root,COG0805@2|Bacteria,46T26@74201|Verrucomicrobia,2ITNJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YHH3_k127_7530706_0	583355.Caka_2519	0.0	1301.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46TNN@74201|Verrucomicrobia,3K7A5@414999|Opitutae	414999|Opitutae	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH3_k127_7530706_1	583355.Caka_1216	1.755e-61	216.0	COG2151@1|root,COG2151@2|Bacteria,46VI1@74201|Verrucomicrobia,3K7B6@414999|Opitutae	414999|Opitutae	S	FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
YHH3_k127_7530706_3	382464.ABSI01000005_gene1097	1.956e-15	77.0	COG0719@1|root,COG0719@2|Bacteria,46S8S@74201|Verrucomicrobia,2ITRN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
YHH3_k127_7545772_3	349521.HCH_02206	1.651e-11	66.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XN1Z@135619|Oceanospirillales	135619|Oceanospirillales	E	Required for the activity of the bacterial periplasmic transport system of putrescine	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
YHH3_k127_7545772_0	278957.ABEA03000193_gene1033	1.828e-149	494.0	COG0661@1|root,COG0661@2|Bacteria,46UJV@74201|Verrucomicrobia,3K7NS@414999|Opitutae	414999|Opitutae	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
YHH3_k127_7545772_2	382464.ABSI01000011_gene2987	1.726e-17	86.0	COG3937@1|root,COG3937@2|Bacteria,46WXZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7545772_4	1121887.AUDK01000003_gene2726	1.51e-10	70.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia,2NU4E@237|Flavobacterium	976|Bacteroidetes	T	BatE protein	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
YHH3_k127_7545772_1	1167006.UWK_00741	2.853e-38	162.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2WM9F@28221|Deltaproteobacteria,2MJ6C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
YHH3_k127_7553289_1	583355.Caka_2010	1.665e-88	300.0	COG2120@1|root,COG2120@2|Bacteria,46TIV@74201|Verrucomicrobia,3K78W@414999|Opitutae	414999|Opitutae	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YHH3_k127_7553289_2	583355.Caka_1469	1.036e-86	291.0	COG0321@1|root,COG0321@2|Bacteria,46T11@74201|Verrucomicrobia,3K7XY@414999|Opitutae	414999|Opitutae	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YHH3_k127_7553289_0	278957.ABEA03000021_gene1712	1.007e-132	428.0	COG0320@1|root,COG0320@2|Bacteria,46TZG@74201|Verrucomicrobia,3K7A4@414999|Opitutae	414999|Opitutae	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
YHH3_k127_7553289_3	395493.BegalDRAFT_2236	0.0002699	44.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7575801_0	595460.RRSWK_06974	3.338e-06	58.0	COG1404@1|root,COG3291@1|root,COG5337@1|root,COG5549@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria,COG5549@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
YHH3_k127_7601352_0	706587.Desti_2615	4.759e-306	945.0	COG4799@1|root,COG4799@2|Bacteria,1Q9BU@1224|Proteobacteria,42P34@68525|delta/epsilon subdivisions,2WK9S@28221|Deltaproteobacteria,2MR7C@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	gcdA	-	4.1.1.70	ko:K01615	ko00362,ko00650,ko01120,map00362,map00650,map01120	-	R03028	RC00832	ko00000,ko00001,ko01000,ko02000	3.B.1.1.3	-	-	Carboxyl_trans
YHH3_k127_7601352_1	1265505.ATUG01000002_gene1832	1.31e-59	208.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NHU@68525|delta/epsilon subdivisions,2WIZ1@28221|Deltaproteobacteria,2MIQ6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YHH3_k127_7603196_0	794903.OPIT5_10955	4.556e-125	418.0	2DBTD@1|root,2ZAXA@2|Bacteria,46WE4@74201|Verrucomicrobia,3K9X9@414999|Opitutae	414999|Opitutae	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
YHH3_k127_7603196_1	595460.RRSWK_03696	7.741e-91	310.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YHH3_k127_7651685_4	382464.ABSI01000013_gene1770	1.681e-26	115.0	COG1579@1|root,COG1579@2|Bacteria,46T10@74201|Verrucomicrobia,2IUE8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
YHH3_k127_7651685_0	452637.Oter_2793	1.62e-118	395.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,46SH2@74201|Verrucomicrobia,3K7MN@414999|Opitutae	414999|Opitutae	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
YHH3_k127_7651685_1	794903.OPIT5_06525	2.327e-101	340.0	COG4974@1|root,COG4974@2|Bacteria,46SSD@74201|Verrucomicrobia,3K7RA@414999|Opitutae	414999|Opitutae	D	tyrosine recombinase	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH3_k127_7651685_2	583355.Caka_1393	1.697e-88	302.0	COG0685@1|root,COG0685@2|Bacteria,46U74@74201|Verrucomicrobia,3K7A3@414999|Opitutae	414999|Opitutae	C	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
YHH3_k127_7651685_3	794903.OPIT5_21360	1.508e-70	241.0	COG0820@1|root,COG0820@2|Bacteria,46UPK@74201|Verrucomicrobia,3K7AA@414999|Opitutae	414999|Opitutae	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
YHH3_k127_7656425_3	794903.OPIT5_15420	1.438e-44	168.0	COG1082@1|root,COG1082@2|Bacteria,46XIH@74201|Verrucomicrobia,3K8KZ@414999|Opitutae	414999|Opitutae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_7656425_2	583355.Caka_2162	5.274e-52	189.0	COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia,3K843@414999|Opitutae	414999|Opitutae	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
YHH3_k127_7656425_1	583355.Caka_0906	2.488e-66	247.0	2EWFD@1|root,33PTV@2|Bacteria,46UNG@74201|Verrucomicrobia,3K7NI@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7656425_4	382464.ABSI01000016_gene688	1.966e-42	172.0	COG4942@1|root,COG4942@2|Bacteria,46U5A@74201|Verrucomicrobia	74201|Verrucomicrobia	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7656425_0	452637.Oter_2116	8.604e-107	353.0	COG4956@1|root,COG4956@2|Bacteria,46TFJ@74201|Verrucomicrobia,3K8ZF@414999|Opitutae	414999|Opitutae	S	SMART Nucleotide binding protein PINc	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7670135_2	1121405.dsmv_1252	1.386e-15	84.0	COG0204@1|root,COG0204@2|Bacteria,1PY44@1224|Proteobacteria,42NR4@68525|delta/epsilon subdivisions,2WKKQ@28221|Deltaproteobacteria,2MJWD@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YHH3_k127_7670135_1	452637.Oter_2726	4.242e-88	301.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
YHH3_k127_7670135_0	794903.OPIT5_18300	4.312e-96	331.0	COG1132@1|root,COG1132@2|Bacteria,46S6K@74201|Verrucomicrobia,3K7CG@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
YHH3_k127_7692061_0	497964.CfE428DRAFT_0927	6.344e-134	437.0	COG0644@1|root,COG0644@2|Bacteria,46TJ0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
YHH3_k127_7692061_3	1249627.D779_2649	1.033e-07	63.0	COG0398@1|root,COG0398@2|Bacteria,1NPV8@1224|Proteobacteria,1SJGC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH3_k127_7692061_1	1121285.AUFK01000014_gene2773	1.843e-20	93.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,1I3W1@117743|Flavobacteriia,3ZSJ6@59732|Chryseobacterium	976|Bacteroidetes	IQ	acyl carrier protein	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
YHH3_k127_7692061_2	177439.DP1840	4.802e-16	90.0	COG0304@1|root,COG0304@2|Bacteria,1RAFK@1224|Proteobacteria,42R69@68525|delta/epsilon subdivisions,2WMWJ@28221|Deltaproteobacteria,2MK3V@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH3_k127_7703967_0	880073.Calab_1626	8.282e-33	129.0	COG4656@1|root,COG4656@2|Bacteria,2NQD0@2323|unclassified Bacteria	2|Bacteria	C	RnfC Barrel sandwich hybrid domain	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
YHH3_k127_7704442_0	56780.SYN_02074	1.743e-263	818.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MQ80@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family	acrB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YHH3_k127_7704442_1	335543.Sfum_3680	1.236e-165	530.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42NHV@68525|delta/epsilon subdivisions,2WJBA@28221|Deltaproteobacteria,2MR20@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
YHH3_k127_7704442_2	933262.AXAM01000002_gene571	1.056e-34	133.0	COG1309@1|root,COG1309@2|Bacteria,1RCDH@1224|Proteobacteria,42VJ5@68525|delta/epsilon subdivisions,2WN7N@28221|Deltaproteobacteria,2MJWS@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
YHH3_k127_7740199_0	794903.OPIT5_18610	2.055e-204	653.0	COG0507@1|root,COG0507@2|Bacteria,46U9H@74201|Verrucomicrobia,3K7J4@414999|Opitutae	414999|Opitutae	L	AAA ATPase	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
YHH3_k127_7740199_1	583355.Caka_1263	1.169e-20	94.0	COG0546@1|root,COG0546@2|Bacteria,46VW7@74201|Verrucomicrobia,3K7X3@414999|Opitutae	414999|Opitutae	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YHH3_k127_780464_2	583355.Caka_0163	4.049e-37	143.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia,3K7UB@414999|Opitutae	414999|Opitutae	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
YHH3_k127_780464_0	382464.ABSI01000012_gene2246	1.454e-98	332.0	COG0548@1|root,COG0548@2|Bacteria,46SH9@74201|Verrucomicrobia,2ITVB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Amino acid kinase family	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
YHH3_k127_780464_1	794903.OPIT5_17105	7.59e-89	300.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,3K76X@414999|Opitutae	414999|Opitutae	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YHH3_k127_782337_0	382464.ABSI01000011_gene2759	8.199e-54	191.0	COG0082@1|root,COG0082@2|Bacteria,46SEA@74201|Verrucomicrobia,2ITMN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
YHH3_k127_7853651_1	330214.NIDE0349	7.973e-54	192.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	tesA	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365	Lipase_GDSL_2
YHH3_k127_7853651_0	330214.NIDE0347	1.087e-69	246.0	COG4715@1|root,COG4715@2|Bacteria	2|Bacteria	S	zinc ion binding	yehQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	SWIM
YHH3_k127_7857397_2	583355.Caka_1846	1.309e-53	198.0	COG0265@1|root,COG0265@2|Bacteria,46T0K@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YHH3_k127_7857397_3	583355.Caka_1847	6.313e-07	59.0	2AXA3@1|root,31P96@2|Bacteria,46XVB@74201|Verrucomicrobia,3K8DE@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7857397_1	382464.ABSI01000013_gene1783	4.513e-77	263.0	COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_7857397_0	583355.Caka_2037	1.181e-81	284.0	COG0142@1|root,COG0142@2|Bacteria,46SKW@74201|Verrucomicrobia,3K74B@414999|Opitutae	414999|Opitutae	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH3_k127_7879631_0	1408813.AYMG01000031_gene1494	2.37e-256	844.0	COG2010@1|root,COG3408@1|root,COG4692@1|root,COG2010@2|Bacteria,COG3408@2|Bacteria,COG4692@2|Bacteria,4P055@976|Bacteroidetes,1IUVF@117747|Sphingobacteriia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YHH3_k127_7879631_2	382464.ABSI01000006_gene921	4.411e-116	421.0	COG1073@1|root,COG1073@2|Bacteria,46Z70@74201|Verrucomicrobia,2IWQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
YHH3_k127_7879631_1	661478.OP10G_2146	4.455e-172	555.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YHH3_k127_7880115_0	338966.Ppro_3596	3.196e-156	509.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,43T5Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YHH3_k127_7880115_1	583355.Caka_0911	2.846e-50	191.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia,3K75N@414999|Opitutae	414999|Opitutae	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
YHH3_k127_7880115_2	382464.ABSI01000021_gene415	3.224e-33	138.0	COG0597@1|root,COG0597@2|Bacteria,46TCC@74201|Verrucomicrobia,2IUIT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
YHH3_k127_7954320_0	382464.ABSI01000011_gene2582	3.968e-135	436.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia,2ITZS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Biotin carboxylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YHH3_k127_7954320_3	382464.ABSI01000011_gene2581	2.525e-42	161.0	COG0511@1|root,COG0511@2|Bacteria,46SXA@74201|Verrucomicrobia,2IUDK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
YHH3_k127_7954320_4	794903.OPIT5_15590	1.038e-22	115.0	COG2982@1|root,COG2982@2|Bacteria,46YU9@74201|Verrucomicrobia,3K7VE@414999|Opitutae	414999|Opitutae	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
YHH3_k127_7954320_2	794903.OPIT5_12790	7.534e-59	227.0	2DN50@1|root,32VJ4@2|Bacteria,46TKZ@74201|Verrucomicrobia,3K748@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
YHH3_k127_7954320_1	583355.Caka_2319	3.5e-89	308.0	COG3225@1|root,COG3225@2|Bacteria,46SRK@74201|Verrucomicrobia,3K735@414999|Opitutae	414999|Opitutae	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
YHH3_k127_7997544_3	583355.Caka_1440	4.006e-07	56.0	COG1579@1|root,COG1579@2|Bacteria,46T10@74201|Verrucomicrobia,3K7Z2@414999|Opitutae	414999|Opitutae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
YHH3_k127_7997544_0	382464.ABSI01000010_gene3600	3.663e-196	633.0	COG1199@1|root,COG1199@2|Bacteria,46SCS@74201|Verrucomicrobia,2ITJT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
YHH3_k127_7997544_1	583355.Caka_1563	2.265e-36	147.0	COG0631@1|root,COG0631@2|Bacteria,46ZFD@74201|Verrucomicrobia,3K84Y@414999|Opitutae	414999|Opitutae	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
YHH3_k127_7997544_2	583355.Caka_2338	2.031e-12	69.0	COG0553@1|root,COG0553@2|Bacteria,46UW7@74201|Verrucomicrobia,3K7NY@414999|Opitutae	414999|Opitutae	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH3_k127_8008524_0	391598.FBBAL38_11599	3.004e-110	377.0	2EXY1@1|root,33R74@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
YHH3_k127_8010501_0	876044.IMCC3088_784	8.491e-90	307.0	COG1914@1|root,COG1914@2|Bacteria,1R6Y2@1224|Proteobacteria,1S0IP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1914 Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
YHH3_k127_8010501_1	251221.35213602	7.162e-46	179.0	COG0667@1|root,COG0667@2|Bacteria,1G2DX@1117|Cyanobacteria	1117|Cyanobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_8010501_2	1185876.BN8_00084	6.91e-26	112.0	COG1082@1|root,COG1082@2|Bacteria,4NIG9@976|Bacteroidetes,47NIT@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_8018798_5	1408473.JHXO01000006_gene1129	0.0001659	51.0	COG3211@1|root,COG4935@1|root,COG3211@2|Bacteria,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,2G16U@200643|Bacteroidia	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
YHH3_k127_8018798_1	382464.ABSI01000005_gene1193	3.596e-109	360.0	COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia,2IU01@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YHH3_k127_8018798_3	452637.Oter_2990	3.926e-54	201.0	COG0571@1|root,COG0571@2|Bacteria,46T3X@74201|Verrucomicrobia,3K7WR@414999|Opitutae	414999|Opitutae	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YHH3_k127_8018798_0	382464.ABSI01000005_gene1191	0.0	1054.0	COG1197@1|root,COG1197@2|Bacteria,46S6Y@74201|Verrucomicrobia,2ITM9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	TRCF	-	-	-	-	-	-	-	-	-	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
YHH3_k127_8018798_2	583355.Caka_0848	1.066e-89	306.0	COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia,3K7AR@414999|Opitutae	414999|Opitutae	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
YHH3_k127_8018798_4	382464.ABSI01000011_gene3187	1.045e-29	130.0	COG0815@1|root,COG0815@2|Bacteria,46W4F@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the fatty acyl group on membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8022399_0	497964.CfE428DRAFT_2851	6.926e-39	151.0	2F7XU@1|root,340BQ@2|Bacteria,46VS8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_810231_0	102125.Xen7305DRAFT_00020060	4.839e-43	178.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,VCBS
YHH3_k127_8115041_0	1279017.AQYJ01000026_gene259	2.131e-43	180.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179,ko:K03932	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	CE1,GH5,GH9	-	CBM_2,CBM_4_9,Cellulase,Glyco_hydro_16,PSCyt3,PSD3,PSD4,PSD5,RicinB_lectin_2,YceI
YHH3_k127_8125792_0	998674.ATTE01000001_gene3304	7.536e-138	445.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATPase, AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YHH3_k127_8125792_2	298655.KI912267_gene6647	1.309e-12	72.0	COG3744@1|root,COG3744@2|Bacteria,2GS3K@201174|Actinobacteria,4EW60@85013|Frankiales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_8125792_1	382464.ABSI01000012_gene2193	8.95e-130	442.0	COG5616@1|root,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_16
YHH3_k127_813551_1	1279015.KB908454_gene932	5.724e-55	207.0	COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,1RPS5@1236|Gammaproteobacteria,1Y5XT@135624|Aeromonadales	135624|Aeromonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
YHH3_k127_813551_0	525897.Dbac_1086	6.108e-90	314.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria,2MA00@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
YHH3_k127_8142290_1	1123242.JH636434_gene4756	2.522e-172	559.0	COG1132@1|root,COG1132@2|Bacteria,2IXW3@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH3_k127_8142290_0	794903.OPIT5_05295	4.43e-201	644.0	COG1132@1|root,COG1132@2|Bacteria,46YXP@74201|Verrucomicrobia,3K7FZ@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YHH3_k127_8142290_2	1122176.KB903540_gene104	1.819e-60	218.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IUTX@117747|Sphingobacteriia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
YHH3_k127_8142547_0	525897.Dbac_1431	2.137e-154	505.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2M8HN@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_3,PAS_4,PAS_9,Sigma54_activat
YHH3_k127_8183733_0	1183438.GKIL_4354	9.627e-115	396.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YHH3_k127_8183733_1	382464.ABSI01000013_gene1860	7.844e-100	331.0	COG1136@1|root,COG1136@2|Bacteria,46TVQ@74201|Verrucomicrobia,2IWNG@203494|Verrucomicrobiae	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_8183733_2	926566.Terro_2397	2.179e-21	95.0	COG0845@1|root,COG0845@2|Bacteria,3Y2FV@57723|Acidobacteria,2JHN2@204432|Acidobacteriia	204432|Acidobacteriia	M	MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
YHH3_k127_8228784_1	382464.ABSI01000012_gene1972	1.188e-89	303.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46URT@74201|Verrucomicrobia,2IV35@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
YHH3_k127_8228784_2	452637.Oter_1403	1.506e-41	155.0	COG3123@1|root,COG3123@2|Bacteria,46VVG@74201|Verrucomicrobia,3K88M@414999|Opitutae	414999|Opitutae	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
YHH3_k127_8228784_0	452637.Oter_3889	6.206e-111	367.0	COG2025@1|root,COG2025@2|Bacteria	2|Bacteria	C	fatty acid beta-oxidation using acyl-CoA dehydrogenase	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	Acyl-CoA_dh_1,ETF,ETF_alpha
YHH3_k127_8235196_0	478741.JAFS01000001_gene1830	1.453e-57	216.0	COG0318@1|root,COG0318@2|Bacteria,46T7I@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
YHH3_k127_8235196_1	91604.ID47_05950	3.332e-07	62.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2U3X4@28211|Alphaproteobacteria,47G4E@766|Rickettsiales	766|Rickettsiales	S	exporter	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8237684_2	1293054.HSACCH_01094	4.164e-39	147.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,249QG@186801|Clostridia	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
YHH3_k127_8237684_3	452637.Oter_0468	3.826e-19	90.0	28X6Y@1|root,2ZJ59@2|Bacteria,46WIZ@74201|Verrucomicrobia,3K8DC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8237684_0	583355.Caka_0388	1.082e-153	497.0	COG0151@1|root,COG0151@2|Bacteria,46SGJ@74201|Verrucomicrobia,3K7MF@414999|Opitutae	414999|Opitutae	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YHH3_k127_8237684_1	926566.Terro_0520	5.297e-46	175.0	COG0300@1|root,COG0300@2|Bacteria,3Y3ZM@57723|Acidobacteria,2JID5@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH3_k127_8237684_5	1048983.EL17_18930	1.733e-07	59.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH3_k127_8237684_4	1118235.CAJH01000025_gene1790	1.543e-13	76.0	COG0810@1|root,COG0810@2|Bacteria,1PDQZ@1224|Proteobacteria,1SWIV@1236|Gammaproteobacteria,1X88P@135614|Xanthomonadales	135614|Xanthomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YHH3_k127_8239862_1	452637.Oter_2541	2.919e-26	120.0	COG0553@1|root,COG0553@2|Bacteria,46UW7@74201|Verrucomicrobia,3K7NY@414999|Opitutae	414999|Opitutae	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YHH3_k127_8239862_2	583355.Caka_2410	4.1e-23	105.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
YHH3_k127_8239862_0	583355.Caka_3018	2.655e-51	188.0	COG0349@1|root,COG0349@2|Bacteria	2|Bacteria	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5,3.6.4.12	ko:K03466,ko:K03657,ko:K03684,ko:K03724	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03036,ko03400	3.A.12	-	-	DNA_pol_A_exo1,HRDC
YHH3_k127_8239862_3	926569.ANT_10750	2.776e-19	91.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yigM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
YHH3_k127_8252584_2	234267.Acid_0674	8.012e-87	299.0	COG5434@1|root,COG5434@2|Bacteria,3Y3WZ@57723|Acidobacteria	2|Bacteria	M	Belongs to the glycosyl hydrolase 28 family	-	-	3.2.1.15	ko:K01184	ko00040,ko01100,map00040,map01100	M00081	R01982,R02360	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_28,Pectate_lyase_3
YHH3_k127_8252584_0	314230.DSM3645_24165	2.219e-185	596.0	COG0591@1|root,COG0591@2|Bacteria,2IWSN@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_8252584_1	1379701.JPJC01000007_gene3499	2.249e-138	448.0	COG4409@1|root,COG4409@2|Bacteria,1QWFX@1224|Proteobacteria,2TY4Q@28211|Alphaproteobacteria,2K211@204457|Sphingomonadales	204457|Sphingomonadales	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
YHH3_k127_8252584_3	661478.OP10G_2146	1.03e-86	300.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YHH3_k127_8263952_1	382464.ABSI01000010_gene3225	3.571e-25	111.0	COG0845@1|root,COG0845@2|Bacteria,46VEA@74201|Verrucomicrobia,2IUBR@203494|Verrucomicrobiae	74201|Verrucomicrobia	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
YHH3_k127_8263952_0	382464.ABSI01000010_gene3226	1.096e-150	485.0	COG0841@1|root,COG0841@2|Bacteria,46UEW@74201|Verrucomicrobia,2IV6M@203494|Verrucomicrobiae	2|Bacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YHH3_k127_8266283_7	382464.ABSI01000006_gene874	2.352e-22	102.0	COG1595@1|root,COG1595@2|Bacteria,46XM2@74201|Verrucomicrobia,2IW65@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_8266283_1	278957.ABEA03000160_gene18	2.075e-99	341.0	COG0673@1|root,COG0673@2|Bacteria,46XZ7@74201|Verrucomicrobia,3K8NQ@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_8266283_8	583355.Caka_2679	3.721e-22	102.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	-	-	4.3.1.14	ko:K07107,ko:K18014	ko00310,map00310	-	R03030	RC00833	ko00000,ko00001,ko01000	-	-	-	4HBT,4HBT_2
YHH3_k127_8266283_3	583355.Caka_2479	5.08e-93	316.0	COG0451@1|root,COG0451@2|Bacteria,46UBJ@74201|Verrucomicrobia,3K7JK@414999|Opitutae	414999|Opitutae	M	3-beta hydroxysteroid dehydrogenase	-	-	1.1.1.412	ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
YHH3_k127_8266283_0	382464.ABSI01000013_gene1638	3.759e-180	578.0	COG0318@1|root,COG0318@2|Bacteria,46XHF@74201|Verrucomicrobia,2IVXI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
YHH3_k127_8266283_5	583355.Caka_2015	5.28e-55	197.0	COG0041@1|root,COG0041@2|Bacteria,46SRV@74201|Verrucomicrobia,3K82K@414999|Opitutae	414999|Opitutae	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YHH3_k127_8266283_4	497964.CfE428DRAFT_2483	3.486e-70	248.0	COG0697@1|root,COG0697@2|Bacteria,46SR7@74201|Verrucomicrobia	74201|Verrucomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH3_k127_8266283_10	68199.JNZO01000004_gene1788	3.086e-05	51.0	2DDIW@1|root,2ZI9I@2|Bacteria,2IQ24@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8266283_2	1121440.AUMA01000020_gene1959	4.98e-95	319.0	COG1092@1|root,COG1092@2|Bacteria,1Q08C@1224|Proteobacteria,42RRW@68525|delta/epsilon subdivisions,2WNY5@28221|Deltaproteobacteria,2MAYH@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
YHH3_k127_8266283_6	629265.PMA4326_03734	1.915e-50	184.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,1Z500@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
YHH3_k127_8281055_3	497964.CfE428DRAFT_2852	1.036e-14	78.0	2BZ98@1|root,2ZRHF@2|Bacteria,46WMB@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8281055_0	497964.CfE428DRAFT_2853	4.793e-140	459.0	COG3522@1|root,COG3522@2|Bacteria,46UPG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VasE
YHH3_k127_8281055_2	497964.CfE428DRAFT_2854	6.767e-41	160.0	2DXSN@1|root,346BX@2|Bacteria,46W22@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Type VI secretion system protein DotU	-	-	-	-	-	-	-	-	-	-	-	-	DotU
YHH3_k127_8281055_1	1396141.BATP01000024_gene782	6.979e-101	355.0	COG3523@1|root,COG3523@2|Bacteria,46VI0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ImcF-related N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ImcF-related_N
YHH3_k127_8339199_0	1499967.BAYZ01000080_gene895	3.144e-59	209.0	COG0500@1|root,COG2226@2|Bacteria,2NP8K@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	arsM	-	2.1.1.137,2.1.1.79	ko:K00574,ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
YHH3_k127_8339199_1	382464.ABSI01000021_gene448	1.845e-41	167.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YHH3_k127_8348056_2	452637.Oter_2374	6.944e-25	106.0	COG1430@1|root,COG1430@2|Bacteria,46WD4@74201|Verrucomicrobia,3K83W@414999|Opitutae	414999|Opitutae	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
YHH3_k127_8348056_0	313628.LNTAR_23834	9.381e-119	391.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH3_k127_8348056_1	313628.LNTAR_23829	5.159e-92	321.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH3_k127_8357067_6	1121289.JHVL01000035_gene2611	3.214e-06	49.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,36DNK@31979|Clostridiaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH3_k127_8357067_3	1121116.KB894765_gene703	1.799e-55	213.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,4AA1I@80864|Comamonadaceae	28216|Betaproteobacteria	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	pilB	-	-	ko:K02454,ko:K02504,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH3_k127_8357067_0	583355.Caka_1448	7.455e-169	538.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH3_k127_8357067_5	1157638.KB892165_gene3609	7.249e-52	201.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
YHH3_k127_8357067_1	382464.ABSI01000005_gene1076	2.183e-144	467.0	COG0673@1|root,COG0673@2|Bacteria,46T2R@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_8357067_2	794903.OPIT5_15415	9.361e-141	459.0	COG0673@1|root,COG0673@2|Bacteria,46SBW@74201|Verrucomicrobia,3K8TJ@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_8357067_4	1396141.BATP01000012_gene2704	1.65e-53	190.0	COG1904@1|root,COG1904@2|Bacteria,46SH8@74201|Verrucomicrobia,2ITWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glucuronate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	UxaC
YHH3_k127_837335_1	1049564.TevJSym_bb00050	5.69e-63	222.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
YHH3_k127_837335_0	1049564.TevJSym_bb00040	3.028e-82	284.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
YHH3_k127_837335_2	1283300.ATXB01000001_gene1162	5.456e-07	59.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales	135618|Methylococcales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
YHH3_k127_8384377_2	1121918.ARWE01000001_gene2811	8.172e-05	47.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,42TEX@68525|delta/epsilon subdivisions,2WPG8@28221|Deltaproteobacteria,43T5H@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YHH3_k127_8384377_1	1232410.KI421421_gene3245	8.663e-54	192.0	COG0437@1|root,COG0437@2|Bacteria,1NF8S@1224|Proteobacteria,42WBD@68525|delta/epsilon subdivisions,2WRT3@28221|Deltaproteobacteria,43VH5@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
YHH3_k127_8384377_0	1232410.KI421421_gene3246	2.3e-187	592.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria,43TBB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YHH3_k127_8406236_2	794903.OPIT5_20720	6.374e-47	179.0	28I2Y@1|root,2Z86X@2|Bacteria,46UR6@74201|Verrucomicrobia,3K9B1@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8406236_1	382464.ABSI01000007_gene4152	9.251e-113	376.0	COG0673@1|root,COG0673@2|Bacteria,46W1B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_8406236_0	382464.ABSI01000007_gene4151	2.804e-125	410.0	COG1609@1|root,COG1609@2|Bacteria,46V1T@74201|Verrucomicrobia,2IVXE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI
YHH3_k127_8409276_2	1242864.D187_003866	1.572e-07	66.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
YHH3_k127_8409276_1	1297742.A176_05903	6.489e-10	74.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K14475,ko:K20276	ko02024,ko05143,map02024,map05143	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,RCC1_2
YHH3_k127_8409276_0	401053.AciPR4_2332	5.29e-21	111.0	COG2374@1|root,COG4932@1|root,COG5276@1|root,COG2374@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,3Y8ZJ@57723|Acidobacteria	57723|Acidobacteria	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494
YHH3_k127_8414222_0	1268068.PG5_27970	1.543e-306	959.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	transglutaminase-like	IV02_11925	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
YHH3_k127_8414222_1	1403819.BATR01000181_gene6168	1.064e-10	64.0	COG4581@1|root,COG4581@2|Bacteria,46STC@74201|Verrucomicrobia,2ITV9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Domain of unknown function (DUF3516)	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
YHH3_k127_8415123_0	1121472.AQWN01000011_gene1225	7.449e-265	846.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,26131@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh,Pro_dh
YHH3_k127_8416520_2	452637.Oter_4247	5.886e-36	145.0	COG2197@1|root,COG2197@2|Bacteria,46XU7@74201|Verrucomicrobia,3K85E@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_8416520_0	452637.Oter_3919	3.677e-136	449.0	COG0277@1|root,COG0277@2|Bacteria,46UHB@74201|Verrucomicrobia,3K7CZ@414999|Opitutae	414999|Opitutae	C	PFAM FAD linked oxidase domain protein	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YHH3_k127_8416520_1	583355.Caka_1647	4.394e-52	187.0	COG0105@1|root,COG0105@2|Bacteria,46T8K@74201|Verrucomicrobia,3K85A@414999|Opitutae	414999|Opitutae	F	Nucleoside diphosphate kinase	-	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YHH3_k127_8436054_0	583355.Caka_1928	4.237e-92	322.0	COG0189@1|root,COG0586@1|root,COG1073@1|root,COG0189@2|Bacteria,COG0586@2|Bacteria,COG1073@2|Bacteria,46UXZ@74201|Verrucomicrobia	74201|Verrucomicrobia	HJ	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YHH3_k127_8436054_3	1195246.AGRI_12591	4.149e-25	113.0	COG0204@1|root,COG3332@1|root,COG0204@2|Bacteria,COG3332@2|Bacteria,1RE1W@1224|Proteobacteria,1S59Q@1236|Gammaproteobacteria,46BCD@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
YHH3_k127_8436054_2	382464.ABSI01000005_gene1399	1.447e-27	118.0	COG2318@1|root,COG2318@2|Bacteria,46WF2@74201|Verrucomicrobia,2IWE9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8436054_1	794903.OPIT5_17690	1.56e-28	115.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,46S5K@74201|Verrucomicrobia,3K7D9@414999|Opitutae	414999|Opitutae	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
YHH3_k127_8452952_3	1396141.BATP01000001_gene5334	4.08e-08	59.0	COG4313@1|root,COG4313@2|Bacteria,46UHV@74201|Verrucomicrobia,2IVEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YHH3_k127_8452952_1	382464.ABSI01000001_gene4228	2.702e-87	297.0	COG0327@1|root,COG0327@2|Bacteria,46U7Z@74201|Verrucomicrobia,2IU4W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
YHH3_k127_8452952_2	794903.OPIT5_01100	1.802e-32	127.0	COG0184@1|root,COG0184@2|Bacteria,46T87@74201|Verrucomicrobia,3K894@414999|Opitutae	414999|Opitutae	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
YHH3_k127_8452952_0	583355.Caka_2669	1.011e-158	510.0	COG1185@1|root,COG1185@2|Bacteria,46SBP@74201|Verrucomicrobia,3K7BU@414999|Opitutae	414999|Opitutae	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YHH3_k127_8457374_0	583355.Caka_0983	2.165e-175	556.0	COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
YHH3_k127_8457374_1	497964.CfE428DRAFT_1494	6.116e-85	291.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia	74201|Verrucomicrobia	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
YHH3_k127_8457374_2	794903.OPIT5_13705	1.278e-20	98.0	COG2165@1|root,COG2165@2|Bacteria,46XPT@74201|Verrucomicrobia,3K9K3@414999|Opitutae	414999|Opitutae	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8460434_0	1232410.KI421416_gene2558	6.542e-156	509.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,43S8I@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
YHH3_k127_8466029_0	580340.Tlie_1599	0.0	1057.0	COG0542@1|root,COG0542@2|Bacteria,3TA3A@508458|Synergistetes	508458|Synergistetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH3_k127_8466029_1	382464.ABSI01000009_gene3940	7.011e-41	154.0	COG2992@1|root,COG2992@2|Bacteria	2|Bacteria	S	amidase activity	-	-	-	ko:K03796	-	-	-	-	ko00000	-	GH73	-	Glucosaminidase
YHH3_k127_8478335_3	583355.Caka_1800	8.798e-26	109.0	COG2042@1|root,COG2042@2|Bacteria	2|Bacteria	S	rRNA processing	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	DTW,Ribo_biogen_C
YHH3_k127_8478335_2	794903.OPIT5_01490	4.644e-55	203.0	COG0283@1|root,COG0283@2|Bacteria,46V54@74201|Verrucomicrobia,3K7W8@414999|Opitutae	414999|Opitutae	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
YHH3_k127_8478335_0	583355.Caka_2286	4.17e-117	391.0	COG0128@1|root,COG0128@2|Bacteria,46TZ7@74201|Verrucomicrobia,3K8ZX@414999|Opitutae	414999|Opitutae	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
YHH3_k127_8478335_1	583355.Caka_2287	3.446e-88	301.0	COG0287@1|root,COG0287@2|Bacteria,46URU@74201|Verrucomicrobia,3K7XP@414999|Opitutae	414999|Opitutae	E	Prephenate dehydrogenase	-	-	1.3.1.12,1.3.1.43	ko:K00220	ko00400,ko00401,ko01100,ko01110,ko01230,map00400,map00401,map01100,map01110,map01230	M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
YHH3_k127_8495897_1	595460.RRSWK_04038	1.423e-54	198.0	COG3119@1|root,COG5434@1|root,COG3119@2|Bacteria,COG5434@2|Bacteria,2IX9T@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF4976,Glyco_hydro_28,Pectate_lyase_3,Sulfatase
YHH3_k127_8495897_0	762984.HMPREF9445_01947	1.844e-90	312.0	COG2755@1|root,COG2755@2|Bacteria,4NK31@976|Bacteroidetes,2G3HM@200643|Bacteroidia,4AWEB@815|Bacteroidaceae	976|Bacteroidetes	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
YHH3_k127_8502858_2	1232453.BAIF02000008_gene3029	2.511e-91	304.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
YHH3_k127_8502858_1	278957.ABEA03000133_gene1593	2.974e-103	341.0	COG0149@1|root,COG0149@2|Bacteria,46SNB@74201|Verrucomicrobia,3K7RD@414999|Opitutae	414999|Opitutae	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
YHH3_k127_8502858_0	583355.Caka_2992	2.521e-134	433.0	COG0126@1|root,COG0126@2|Bacteria,46SI9@74201|Verrucomicrobia,3K76C@414999|Opitutae	414999|Opitutae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
YHH3_k127_8507289_0	379066.GAU_0844	1.176e-91	310.0	COG1136@1|root,COG1136@2|Bacteria,1ZUSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YHH3_k127_8507289_1	517418.Ctha_0502	1.476e-65	235.0	COG0577@1|root,COG0577@2|Bacteria,1FDCY@1090|Chlorobi	1090|Chlorobi	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
YHH3_k127_8531283_1	382464.ABSI01000011_gene3088	4.952e-21	94.0	COG2258@1|root,COG2258@2|Bacteria,46VBP@74201|Verrucomicrobia,2IUHR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8531283_0	583355.Caka_0336	5.574e-83	290.0	COG0303@1|root,COG0303@2|Bacteria,46SZB@74201|Verrucomicrobia,3K916@414999|Opitutae	414999|Opitutae	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_N
YHH3_k127_8531283_2	1337936.IJ00_22705	6.39e-05	48.0	COG0315@1|root,COG0315@2|Bacteria,1G53K@1117|Cyanobacteria,1HMKF@1161|Nostocales	1117|Cyanobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
YHH3_k127_8622977_0	794903.OPIT5_05405	1.18e-157	507.0	COG4198@1|root,COG4198@2|Bacteria,46S83@74201|Verrucomicrobia,3K7UU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
YHH3_k127_8622977_2	247490.KSU1_B0086	5.622e-08	57.0	2ECNM@1|root,336KG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YHH3_k127_8622977_4	888060.HMPREF9081_0527	2.568e-05	49.0	COG2026@1|root,COG2026@2|Bacteria,1UHB8@1239|Firmicutes,4H86B@909932|Negativicutes	909932|Negativicutes	DJ	ParE toxin of type II toxin-antitoxin system, parDE	relE	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8622977_1	583355.Caka_0238	9.235e-70	250.0	COG0701@1|root,COG0701@2|Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,HMA
YHH3_k127_8622977_3	981085.XP_010094486.1	1.415e-07	59.0	KOG1127@1|root,KOG1127@2759|Eukaryota,37HQQ@33090|Viridiplantae,3GDEP@35493|Streptophyta,4JGJC@91835|fabids	35493|Streptophyta	A	Tetratricopeptide repeat protein	-	GO:0000184,GO:0000288,GO:0000291,GO:0000785,GO:0000956,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016441,GO:0016458,GO:0019222,GO:0019439,GO:0032991,GO:0034427,GO:0034641,GO:0034655,GO:0035327,GO:0040029,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043928,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0055087,GO:0060255,GO:0065007,GO:0070478,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_16,TPR_2,TPR_8
YHH3_k127_8685604_2	583355.Caka_1121	4.555e-101	332.0	COG0524@1|root,COG0524@2|Bacteria,46TGU@74201|Verrucomicrobia,3K7M0@414999|Opitutae	414999|Opitutae	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
YHH3_k127_8685604_1	583355.Caka_2861	6.869e-113	370.0	COG1028@1|root,COG1028@2|Bacteria,46UZ1@74201|Verrucomicrobia,3K7C4@414999|Opitutae	414999|Opitutae	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH3_k127_8685604_0	234267.Acid_5330	1.531e-133	433.0	COG1904@1|root,COG1904@2|Bacteria,3Y2S9@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
YHH3_k127_8689894_2	583355.Caka_1610	2.092e-87	296.0	COG1043@1|root,COG1043@2|Bacteria,46SD4@74201|Verrucomicrobia,3K7A9@414999|Opitutae	414999|Opitutae	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
YHH3_k127_8689894_5	583355.Caka_2598	2.282e-67	233.0	COG0231@1|root,COG0231@2|Bacteria,46SQH@74201|Verrucomicrobia,3K7PZ@414999|Opitutae	414999|Opitutae	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YHH3_k127_8689894_0	583355.Caka_1611	6.275e-194	614.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,46SG1@74201|Verrucomicrobia,3K7GH@414999|Opitutae	414999|Opitutae	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
YHH3_k127_8689894_7	313624.NSP_5360	1.644e-43	161.0	COG0537@1|root,COG0537@2|Bacteria,1G6R2@1117|Cyanobacteria,1HNI6@1161|Nostocales	1117|Cyanobacteria	FG	PFAM Histidine triad (HIT) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
YHH3_k127_8689894_4	452637.Oter_0180	1.043e-75	267.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia,3K7BD@414999|Opitutae	414999|Opitutae	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
YHH3_k127_8689894_1	583355.Caka_1832	2.49e-96	335.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,46S7Z@74201|Verrucomicrobia,3K7FH@414999|Opitutae	414999|Opitutae	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
YHH3_k127_8689894_6	452637.Oter_0183	1.811e-45	169.0	COG0736@1|root,COG0736@2|Bacteria,46T5U@74201|Verrucomicrobia,3K85Z@414999|Opitutae	414999|Opitutae	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
YHH3_k127_8689894_3	382464.ABSI01000011_gene2637	5.228e-87	299.0	COG0854@1|root,COG0854@2|Bacteria,46SJT@74201|Verrucomicrobia,2ITP1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
YHH3_k127_8689894_8	794903.OPIT5_17270	3.317e-20	92.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia,3K7VV@414999|Opitutae	414999|Opitutae	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH3_k127_869601_2	452637.Oter_0500	1.846e-62	226.0	COG0169@1|root,COG0169@2|Bacteria,46SVF@74201|Verrucomicrobia,3K7SU@414999|Opitutae	414999|Opitutae	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
YHH3_k127_869601_1	452637.Oter_0499	4.843e-73	256.0	COG2912@1|root,COG2912@2|Bacteria,46T9F@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
YHH3_k127_869601_3	583355.Caka_1273	1.721e-39	151.0	COG0261@1|root,COG0261@2|Bacteria,46VNZ@74201|Verrucomicrobia,3K87S@414999|Opitutae	414999|Opitutae	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
YHH3_k127_869601_4	382464.ABSI01000023_gene612	4.274e-31	123.0	COG0211@1|root,COG0211@2|Bacteria,46T48@74201|Verrucomicrobia,2IUMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L27 protein	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YHH3_k127_869601_0	1499968.TCA2_5205	4.486e-85	316.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1U78N@1239|Firmicutes,4HFCP@91061|Bacilli,27742@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	ETR2	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
YHH3_k127_869601_5	583355.Caka_2567	2.934e-21	98.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YHH3_k127_869601_6	452637.Oter_4040	3.832e-18	90.0	COG3784@1|root,COG3784@2|Bacteria,46WPU@74201|Verrucomicrobia,3K8CB@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1318)	-	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
YHH3_k127_869601_7	525897.Dbac_2330	0.0001568	48.0	2EIZA@1|root,33CQH@2|Bacteria,1NJDM@1224|Proteobacteria,42WT9@68525|delta/epsilon subdivisions,2WT1N@28221|Deltaproteobacteria,2ME4V@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_19
YHH3_k127_875769_1	382464.ABSI01000013_gene1792	1.35e-92	321.0	COG0626@1|root,COG0626@2|Bacteria,46UUN@74201|Verrucomicrobia,2ITMP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
YHH3_k127_875769_0	583355.Caka_1808	1.512e-159	512.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,3K7IM@414999|Opitutae	414999|Opitutae	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YHH3_k127_875769_2	452637.Oter_2710	4.68e-54	201.0	COG0438@1|root,COG0438@2|Bacteria,46U8D@74201|Verrucomicrobia,3K8XI@414999|Opitutae	414999|Opitutae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_8864919_1	583355.Caka_1430	3.032e-185	587.0	COG0282@1|root,COG0282@2|Bacteria,46TZF@74201|Verrucomicrobia,3K7U1@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
YHH3_k127_8864919_0	583355.Caka_1429	0.0	1055.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,46SP5@74201|Verrucomicrobia,3K793@414999|Opitutae	74201|Verrucomicrobia	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
YHH3_k127_8864919_5	583355.Caka_2978	2.549e-13	72.0	COG0291@1|root,COG0291@2|Bacteria,46TCI@74201|Verrucomicrobia,3K8DB@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
YHH3_k127_8864919_4	583355.Caka_2979	2.837e-40	152.0	COG0292@1|root,COG0292@2|Bacteria,46SZW@74201|Verrucomicrobia,3K87I@414999|Opitutae	414999|Opitutae	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
YHH3_k127_8864919_2	382464.ABSI01000023_gene556	2.922e-148	476.0	COG0016@1|root,COG0016@2|Bacteria,46S6R@74201|Verrucomicrobia,2ITTX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YHH3_k127_8864919_3	526218.Sterm_4096	1.857e-138	467.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,378F8@32066|Fusobacteria	32066|Fusobacteria	J	Phenylalanyl-tRNA synthetase beta	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
YHH3_k127_8873350_1	1095769.CAHF01000017_gene18	6.892e-61	216.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,2VZMU@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH3_k127_8873350_0	1002809.SSIL_2408	3.05e-164	530.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,26DUZ@186818|Planococcaceae	91061|Bacilli	E	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YHH3_k127_8899841_1	382464.ABSI01000011_gene3128	1.935e-63	222.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
YHH3_k127_8899841_0	382464.ABSI01000013_gene1502	1.44e-176	563.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,2ITWC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ammonium Transporter Family	-	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
YHH3_k127_8899841_2	1499967.BAYZ01000041_gene2377	3.291e-58	208.0	COG0551@1|root,COG0551@2|Bacteria,2NQZQ@2323|unclassified Bacteria	2|Bacteria	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YHH3_k127_8899841_3	583355.Caka_2675	2.361e-32	129.0	COG2940@1|root,COG2940@2|Bacteria	2|Bacteria	K	SET domain	CP_0991	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
YHH3_k127_8904435_1	55601.VANGNB10_cI1762	1.122e-06	57.0	COG2834@1|root,COG2834@2|Bacteria,1R5HR@1224|Proteobacteria,1RSIT@1236|Gammaproteobacteria,1XV2C@135623|Vibrionales	135623|Vibrionales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
YHH3_k127_8904435_0	400668.Mmwyl1_3882	6.206e-11	75.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,1RMP8@1236|Gammaproteobacteria,1XH8E@135619|Oceanospirillales	135619|Oceanospirillales	S	exporter	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
YHH3_k127_8946470_2	382464.ABSI01000006_gene776	3.105e-14	79.0	COG0848@1|root,COG0848@2|Bacteria,46WPD@74201|Verrucomicrobia,2IUY5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
YHH3_k127_8946470_1	382464.ABSI01000006_gene777	7.544e-21	97.0	COG0848@1|root,COG0848@2|Bacteria,46W26@74201|Verrucomicrobia,2IUYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
YHH3_k127_8946470_0	583355.Caka_1477	1.092e-52	191.0	COG2197@1|root,COG2197@2|Bacteria,46T2B@74201|Verrucomicrobia,3K7X9@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YHH3_k127_8959374_0	340177.Cag_1563	1.232e-148	490.0	COG0653@1|root,COG0653@2|Bacteria,1FDBP@1090|Chlorobi	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA2	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH3_k127_8959374_1	340177.Cag_1407	1.587e-97	334.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YHH3_k127_9017583_3	794903.OPIT5_26195	6.749e-07	59.0	COG3209@1|root,COG3209@2|Bacteria,46Z8T@74201|Verrucomicrobia	74201|Verrucomicrobia	M	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9017583_2	870187.Thini_1711	3.22e-34	137.0	COG1848@1|root,COG1848@2|Bacteria,1N8VX@1224|Proteobacteria,1SP0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_9017583_0	794903.OPIT5_14640	8.738e-203	642.0	COG1190@1|root,COG1190@2|Bacteria,46TIA@74201|Verrucomicrobia,3K7FJ@414999|Opitutae	414999|Opitutae	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YHH3_k127_9017583_1	794903.OPIT5_14635	5.098e-77	270.0	COG4591@1|root,COG4591@2|Bacteria,46SKZ@74201|Verrucomicrobia,3K74K@414999|Opitutae	414999|Opitutae	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
YHH3_k127_9030120_1	1122925.KB895383_gene3404	5.617e-08	56.0	COG1595@1|root,COG1595@2|Bacteria,1V89Y@1239|Firmicutes,4HIY2@91061|Bacilli,2752K@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70 region 2	sigX_2	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YHH3_k127_9030120_0	583355.Caka_1390	7.836e-52	188.0	COG3494@1|root,COG3494@2|Bacteria,46SJ6@74201|Verrucomicrobia,3K77G@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
YHH3_k127_9095215_1	583355.Caka_1872	2.481e-147	482.0	COG1418@1|root,COG1418@2|Bacteria,46U1S@74201|Verrucomicrobia,3K7E0@414999|Opitutae	414999|Opitutae	A	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
YHH3_k127_9095215_2	583355.Caka_1738	1.948e-108	359.0	COG0479@1|root,COG0479@2|Bacteria,46S82@74201|Verrucomicrobia,3K7PU@414999|Opitutae	414999|Opitutae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
YHH3_k127_9095215_0	583355.Caka_1739	7.849e-148	475.0	COG1053@1|root,COG1053@2|Bacteria,46S7D@74201|Verrucomicrobia,3K754@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YHH3_k127_9116277_2	583355.Caka_1633	1.269e-120	396.0	COG0714@1|root,COG0714@2|Bacteria,46SKP@74201|Verrucomicrobia,3K7DY@414999|Opitutae	414999|Opitutae	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YHH3_k127_9116277_0	382464.ABSI01000010_gene3676	3.264e-185	591.0	COG2204@1|root,COG2204@2|Bacteria,46SDB@74201|Verrucomicrobia,2IU0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
YHH3_k127_9116277_1	1120973.AQXL01000134_gene1536	6.356e-172	568.0	COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli,278RF@186823|Alicyclobacillaceae	91061|Bacilli	C	Phosphoenolpyruvate carboxylase	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
YHH3_k127_9116277_3	1521187.JPIM01000035_gene3407	2.684e-118	392.0	COG0026@1|root,COG0026@2|Bacteria,2G5PV@200795|Chloroflexi,375PJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
YHH3_k127_9116277_5	765420.OSCT_1289	1.766e-61	216.0	COG0041@1|root,COG0041@2|Bacteria,2G6JS@200795|Chloroflexi,375UD@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YHH3_k127_9116277_4	357808.RoseRS_1985	1.604e-96	331.0	COG3329@1|root,COG3329@2|Bacteria,2GAMM@200795|Chloroflexi,376S1@32061|Chloroflexia	32061|Chloroflexia	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
YHH3_k127_9116277_8	926560.KE387027_gene550	8.637e-16	82.0	COG0347@1|root,COG0347@2|Bacteria,1WK66@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9116277_6	240292.Ava_2502	9.152e-41	166.0	COG2081@1|root,COG2081@2|Bacteria,1FZZ1@1117|Cyanobacteria,1HIQ5@1161|Nostocales	1117|Cyanobacteria	S	TIGRFAM flavoprotein, HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
YHH3_k127_9116277_7	794903.OPIT5_07975	2.71e-20	91.0	2CKAQ@1|root,34BNJ@2|Bacteria,46WDC@74201|Verrucomicrobia,3K83J@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_913178_2	700598.Niako_0063	0.0002646	46.0	COG2407@1|root,COG2407@2|Bacteria,4NFGS@976|Bacteroidetes,1IQRA@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM L-fucose isomerase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
YHH3_k127_913178_0	700598.Niako_3593	4.988e-217	690.0	COG3420@1|root,COG3420@2|Bacteria,4NF5Y@976|Bacteroidetes,1IQQQ@117747|Sphingobacteriia	976|Bacteroidetes	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,rhaM
YHH3_k127_913178_1	1121957.ATVL01000007_gene1530	5.771e-44	178.0	COG3250@1|root,COG3250@2|Bacteria,4NEWP@976|Bacteroidetes,47T9A@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Malectin
YHH3_k127_9132385_7	1089553.Tph_c03590	1.672e-08	60.0	arCOG03330@1|root,2Z82Q@2|Bacteria,1U584@1239|Firmicutes,24B07@186801|Clostridia,42FIS@68295|Thermoanaerobacterales	186801|Clostridia	H	Methanol-cobalamin methyltransferase B subunit	-	-	2.1.1.90	ko:K04480	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R04384,R09098	RC00035,RC01144,RC01145,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	MtaB
YHH3_k127_9132385_5	1168034.FH5T_04680	2.658e-22	102.0	COG2236@1|root,COG2236@2|Bacteria,4NRJB@976|Bacteroidetes,2FS1M@200643|Bacteroidia	976|Bacteroidetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
YHH3_k127_9132385_4	452637.Oter_1098	1.606e-50	187.0	COG1225@1|root,COG1225@2|Bacteria,46VQE@74201|Verrucomicrobia,3K9Z2@414999|Opitutae	414999|Opitutae	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH3_k127_9132385_8	595460.RRSWK_05132	1.223e-07	65.0	COG2374@1|root,COG3210@1|root,COG3391@1|root,COG3420@1|root,COG2374@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K07004,ko:K15125,ko:K20276	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Exo_endo_phos,He_PIG,LTD,PKD
YHH3_k127_9132385_6	56110.Oscil6304_3785	3.918e-20	106.0	2AQRE@1|root,32ZCH@2|Bacteria,1G98G@1117|Cyanobacteria,1HD3A@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9132385_2	1336235.JAEG01000007_gene1436	1.388e-171	549.0	COG0438@1|root,COG0438@2|Bacteria,1MWVX@1224|Proteobacteria,2TV2N@28211|Alphaproteobacteria,4B82K@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Sucrose synthase	mfpsA	GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576	2.4.1.246	ko:K13058	-	-	R08947	RC00005,RC00028	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_9132385_1	1396418.BATQ01000001_gene1266	3.933e-279	876.0	COG0561@1|root,COG3408@1|root,COG0561@2|Bacteria,COG3408@2|Bacteria,46UUJ@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_100,S6PP
YHH3_k127_9132385_3	1089550.ATTH01000001_gene647	2e-61	224.0	COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes	976|Bacteroidetes	G	PfkB family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH3_k127_9132385_0	382464.ABSI01000005_gene1080	9.822e-310	962.0	COG3534@1|root,COG3534@2|Bacteria,46UU3@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
YHH3_k127_9147826_0	521674.Plim_2153	2.805e-119	388.0	COG0191@1|root,COG0191@2|Bacteria,2IYZ9@203682|Planctomycetes	203682|Planctomycetes	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
YHH3_k127_9147826_2	1304872.JAGC01000003_gene3071	1.019e-13	79.0	COG1309@1|root,COG1309@2|Bacteria,1N11B@1224|Proteobacteria,42ZYG@68525|delta/epsilon subdivisions,2WVGK@28221|Deltaproteobacteria,2MB4F@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
YHH3_k127_9147826_1	452637.Oter_2695	3.351e-55	199.0	COG0407@1|root,COG0407@2|Bacteria,46UU6@74201|Verrucomicrobia,3K7H3@414999|Opitutae	414999|Opitutae	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YHH3_k127_9148449_0	382464.ABSI01000007_gene4158	6.14e-167	534.0	COG5426@1|root,COG5426@2|Bacteria,46UZQ@74201|Verrucomicrobia,2IV52@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Lacto-N-biose phosphorylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LBP_C,LBP_M,Lact_bio_phlase
YHH3_k127_9148449_2	1121129.KB903368_gene648	1.93e-53	198.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,2FMRQ@200643|Bacteroidia,22X1I@171551|Porphyromonadaceae	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
YHH3_k127_9148449_1	382464.ABSI01000010_gene3577	3.374e-101	334.0	COG0492@1|root,COG0492@2|Bacteria,46SC1@74201|Verrucomicrobia,2ITP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YHH3_k127_922423_2	518766.Rmar_1517	0.000198	53.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1FJ24@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
YHH3_k127_922423_1	382464.ABSI01000012_gene2134	9.544e-35	141.0	COG0811@1|root,COG0811@2|Bacteria,46SY0@74201|Verrucomicrobia,2IUVE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YHH3_k127_922423_0	1131269.AQVV01000012_gene2619	4.203e-69	252.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	-	-	1.3.99.23,5.2.1.13	ko:K09516,ko:K09835	ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110	M00097	R07163,R07512	RC01835,RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
YHH3_k127_9235776_0	314230.DSM3645_24165	4.45e-176	563.0	COG0591@1|root,COG0591@2|Bacteria,2IWSN@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_9250545_1	382464.ABSI01000012_gene2268	7.61e-35	139.0	COG0486@1|root,COG0486@2|Bacteria,46SIQ@74201|Verrucomicrobia,2ITV2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
YHH3_k127_9250545_0	583355.Caka_2100	2.535e-183	580.0	COG0445@1|root,COG0445@2|Bacteria,46SID@74201|Verrucomicrobia,3K7JB@414999|Opitutae	414999|Opitutae	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
YHH3_k127_9250758_11	1396141.BATP01000002_gene4828	1.979e-27	114.0	COG0215@1|root,COG0215@2|Bacteria,46SES@74201|Verrucomicrobia,2ITI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (C) catalytic domain	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
YHH3_k127_9250758_6	118168.MC7420_1737	1.802e-57	211.0	COG1073@1|root,COG1073@2|Bacteria,1G2EP@1117|Cyanobacteria,1H83Z@1150|Oscillatoriales	1117|Cyanobacteria	S	of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S9
YHH3_k127_9250758_8	55529.EKX54446	5.278e-45	169.0	COG0693@1|root,KOG2764@2759|Eukaryota	2759|Eukaryota	J	guanine deglycation, methylglyoxal removal	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
YHH3_k127_9250758_5	583355.Caka_2985	1.695e-94	323.0	COG0823@1|root,COG0823@2|Bacteria,46SSK@74201|Verrucomicrobia,3K7CU@414999|Opitutae	414999|Opitutae	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
YHH3_k127_9250758_3	583355.Caka_2984	5.908e-120	395.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,46SAV@74201|Verrucomicrobia,3K75Q@414999|Opitutae	414999|Opitutae	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
YHH3_k127_9250758_13	452637.Oter_4589	7.656e-22	96.0	2E99J@1|root,333HQ@2|Bacteria,46T77@74201|Verrucomicrobia,3K8CU@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9250758_10	1173264.KI913949_gene2585	3.315e-30	127.0	COG1738@1|root,COG1738@2|Bacteria	2|Bacteria	S	queuosine salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
YHH3_k127_9250758_0	583355.Caka_0248	3.629e-188	606.0	COG0659@1|root,COG0659@2|Bacteria,46THR@74201|Verrucomicrobia,3K7K8@414999|Opitutae	414999|Opitutae	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
YHH3_k127_9250758_9	452637.Oter_1912	1.591e-30	122.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia,3K8AZ@414999|Opitutae	414999|Opitutae	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
YHH3_k127_9250758_7	1122947.FR7_1217	1.494e-49	183.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4H960@909932|Negativicutes	909932|Negativicutes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH3_k127_9250758_15	583355.Caka_2472	2.488e-11	66.0	COG0230@1|root,COG0230@2|Bacteria,46XWC@74201|Verrucomicrobia,3K8GI@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
YHH3_k127_9250758_14	583355.Caka_2473	1.521e-16	85.0	COG0594@1|root,COG0594@2|Bacteria,46WMC@74201|Verrucomicrobia,3K8HX@414999|Opitutae	414999|Opitutae	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
YHH3_k127_9250758_12	272942.RCAP_rcc00348	8.382e-23	102.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,1FC27@1060|Rhodobacter	28211|Alphaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
YHH3_k127_9250758_2	382464.ABSI01000013_gene1506	9.033e-121	410.0	COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia,2ITX0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
YHH3_k127_9250758_4	583355.Caka_2476	1.593e-100	334.0	COG0217@1|root,COG0217@2|Bacteria,46SP3@74201|Verrucomicrobia,3K74P@414999|Opitutae	414999|Opitutae	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
YHH3_k127_9250758_1	583355.Caka_1589	1.314e-155	500.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia,3K8UM@414999|Opitutae	414999|Opitutae	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH3_k127_9270785_2	583355.Caka_3060	5.401e-125	415.0	COG5434@1|root,COG5434@2|Bacteria,46UV6@74201|Verrucomicrobia,3K97E@414999|Opitutae	414999|Opitutae	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
YHH3_k127_9270785_3	382464.ABSI01000021_gene451	4.452e-111	380.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	VVA1382	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_9270785_0	44056.XP_009035435.1	8.328e-243	762.0	COG3250@1|root,KOG2024@2759|Eukaryota	2759|Eukaryota	G	beta-glucuronidase activity	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
YHH3_k127_9270785_1	1408304.JAHA01000008_gene1815	8.783e-131	439.0	COG4289@1|root,COG4289@2|Bacteria,1TSHI@1239|Firmicutes,249KM@186801|Clostridia,4BX7Q@830|Butyrivibrio	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2264)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2264
YHH3_k127_9277707_0	382464.ABSI01000005_gene1046	7.665e-143	473.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_88
YHH3_k127_9277707_2	1480694.DC28_05935	6.3e-81	276.0	COG1028@1|root,COG1028@2|Bacteria,2J67F@203691|Spirochaetes	203691|Spirochaetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
YHH3_k127_9277707_1	382464.ABSI01000005_gene1045	8.785e-97	323.0	COG3717@1|root,COG3717@2|Bacteria,46TZ9@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
YHH3_k127_9279330_3	497964.CfE428DRAFT_6214	5.849e-12	67.0	COG3250@1|root,COG3250@2|Bacteria,46U8X@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	SASA
YHH3_k127_9279330_1	1161401.ASJA01000018_gene1174	2.499e-22	102.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_4
YHH3_k127_9279330_2	1121403.AUCV01000045_gene1139	7.437e-21	98.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10,Dala_Dala_lig_C,RLAN,RimK
YHH3_k127_9279330_0	1121930.AQXG01000001_gene1561	1.87e-153	498.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,4NF2R@976|Bacteroidetes	976|Bacteroidetes	HJ	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
YHH3_k127_9279891_0	1403819.BATR01000056_gene1757	3.082e-134	441.0	COG2907@1|root,COG2907@2|Bacteria,46SMG@74201|Verrucomicrobia,2IVF5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
YHH3_k127_9279891_2	497964.CfE428DRAFT_5331	9.072e-64	227.0	COG3496@1|root,COG3496@2|Bacteria,46T60@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
YHH3_k127_9279891_1	1408813.AYMG01000007_gene4338	6.821e-124	410.0	COG2230@1|root,COG2230@2|Bacteria,4NHFT@976|Bacteroidetes,1IR28@117747|Sphingobacteriia	976|Bacteroidetes	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
YHH3_k127_9279891_3	629265.PMA4326_17986	1.812e-41	158.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1Z8JP@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
YHH3_k127_9304058_1	382464.ABSI01000021_gene439	4.082e-39	151.0	COG3829@1|root,COG3829@2|Bacteria,46Z7D@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
YHH3_k127_9304058_0	251229.Chro_5505	2.231e-45	178.0	COG3240@1|root,COG3240@2|Bacteria,1FZV1@1117|Cyanobacteria,3VK06@52604|Pleurocapsales	1117|Cyanobacteria	I	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
YHH3_k127_9305172_0	388467.A19Y_0928	4.088e-73	259.0	COG0451@1|root,COG0451@2|Bacteria,1G3VX@1117|Cyanobacteria,1HE17@1150|Oscillatoriales	1117|Cyanobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YHH3_k127_9305172_1	313628.LNTAR_03139	3.98e-67	239.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	XK27_03530	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,rRNA_methylase
YHH3_k127_9305172_2	573065.Astex_0713	6.199e-22	99.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,2KEXP@204458|Caulobacterales	204458|Caulobacterales	H	acetolactate synthase large subunit	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YHH3_k127_9316772_2	870187.Thini_3672	8.977e-37	143.0	COG5573@1|root,COG5573@2|Bacteria,1RKIK@1224|Proteobacteria,1SBYM@1236|Gammaproteobacteria,463SH@72273|Thiotrichales	1236|Gammaproteobacteria	S	COGs COG5573 nucleic-acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_9316772_0	583355.Caka_1040	6.343e-145	479.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	Z012_03425	-	3.1.6.14	ko:K01137,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
YHH3_k127_9316772_3	1454004.AW11_03396	3.851e-05	51.0	COG1848@1|root,COG1848@2|Bacteria,1MYDN@1224|Proteobacteria,2VTED@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YHH3_k127_9316772_1	373903.Hore_04240	4.609e-127	419.0	COG2273@1|root,COG5309@1|root,COG2273@2|Bacteria,COG5309@2|Bacteria,1TR5U@1239|Firmicutes,248GW@186801|Clostridia,3WB6W@53433|Halanaerobiales	186801|Clostridia	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_16
YHH3_k127_9331004_6	1333856.L686_10700	6.058e-06	51.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,1RNZN@1236|Gammaproteobacteria,1Z2AQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	G	Aldose 1-epimerase	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
YHH3_k127_9331004_2	583355.Caka_2414	1.49e-92	321.0	COG1459@1|root,COG1459@2|Bacteria,46UIF@74201|Verrucomicrobia,3K7U0@414999|Opitutae	414999|Opitutae	NU	secretion system	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
YHH3_k127_9331004_0	583355.Caka_2674	4.195e-209	668.0	COG2804@1|root,COG2804@2|Bacteria,46UIY@74201|Verrucomicrobia,3K7E3@414999|Opitutae	414999|Opitutae	NU	Secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
YHH3_k127_9331004_1	583355.Caka_1642	2.28e-128	437.0	COG1450@1|root,COG1450@2|Bacteria,46UJF@74201|Verrucomicrobia,3K7CH@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
YHH3_k127_9331004_3	583355.Caka_1641	5.728e-20	96.0	2BMCF@1|root,32FWN@2|Bacteria,46XUN@74201|Verrucomicrobia,3K8A6@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	T2SSM_b
YHH3_k127_9331004_5	278957.ABEA03000161_gene143	3.116e-06	54.0	COG4972@1|root,COG4972@2|Bacteria,46WVK@74201|Verrucomicrobia,3K8A8@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9336804_0	945713.IALB_0592	5.721e-227	716.0	COG3808@1|root,COG3808@2|Bacteria	2|Bacteria	C	hydrogen-translocating pyrophosphatase activity	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
YHH3_k127_9358888_0	926550.CLDAP_08980	5.538e-160	511.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
YHH3_k127_9358888_1	382464.ABSI01000010_gene3297	1.537e-87	295.0	COG3647@1|root,COG3647@2|Bacteria,46W76@74201|Verrucomicrobia,2IW86@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Predicted membrane protein (DUF2238)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2238
YHH3_k127_9361064_0	382464.ABSI01000016_gene647	3.422e-142	461.0	COG1034@1|root,COG1034@2|Bacteria,46S6S@74201|Verrucomicrobia,2ITJ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
YHH3_k127_9361064_1	583355.Caka_2575	2.497e-132	431.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,3K7UD@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YHH3_k127_9361064_2	583355.Caka_2576	9.966e-88	293.0	COG1143@1|root,COG1143@2|Bacteria,46SNT@74201|Verrucomicrobia,3K7UR@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
YHH3_k127_9388041_1	1194972.MVAC_20153	4.719e-15	79.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_35,CBM_6,He_PIG,Malectin
YHH3_k127_9388041_0	382464.ABSI01000011_gene2710	9.692e-224	704.0	COG0504@1|root,COG0504@2|Bacteria,46S8K@74201|Verrucomicrobia,2ITX8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
YHH3_k127_9390165_0	452637.Oter_0684	1.575e-94	326.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6
YHH3_k127_9390165_2	452637.Oter_0685	5.747e-79	271.0	COG0767@1|root,COG0767@2|Bacteria,46ZIM@74201|Verrucomicrobia,3K7D7@414999|Opitutae	414999|Opitutae	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YHH3_k127_9390165_1	452637.Oter_0686	3.869e-84	286.0	COG1127@1|root,COG1127@2|Bacteria,46SRC@74201|Verrucomicrobia,3K7XJ@414999|Opitutae	414999|Opitutae	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YHH3_k127_9390165_3	1123371.ATXH01000005_gene2035	2.764e-47	183.0	COG1463@1|root,COG1463@2|Bacteria,2GGR8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
YHH3_k127_939384_0	247633.GP2143_05970	4.271e-214	674.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
YHH3_k127_939384_2	382464.ABSI01000011_gene3012	5.054e-52	189.0	COG2094@1|root,COG2094@2|Bacteria,46VAR@74201|Verrucomicrobia,2IV0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Methylpurine-DNA glycosylase (MPG)	-	-	-	-	-	-	-	-	-	-	-	-	Pur_DNA_glyco
YHH3_k127_939384_1	382464.ABSI01000010_gene3368	3.494e-127	413.0	COG4102@1|root,COG4102@2|Bacteria,46T50@74201|Verrucomicrobia,2IUKB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YHH3_k127_9405465_1	382464.ABSI01000011_gene2590	1.604e-89	308.0	COG4773@1|root,COG4773@2|Bacteria,46TH4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_9405465_0	1122176.KB903553_gene3659	1.743e-107	365.0	COG3934@1|root,COG3934@2|Bacteria,4PMNF@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
YHH3_k127_9405465_2	382464.ABSI01000011_gene2586	1.344e-68	240.0	COG1609@1|root,COG1609@2|Bacteria,46XF0@74201|Verrucomicrobia,2IVQK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3
YHH3_k127_9438684_1	583355.Caka_0705	5.107e-84	286.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YHH3_k127_9438684_0	278957.ABEA03000157_gene632	1.553e-100	331.0	COG0667@1|root,COG0667@2|Bacteria,46SC2@74201|Verrucomicrobia,3K7X7@414999|Opitutae	414999|Opitutae	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_9444617_1	583355.Caka_2562	7.183e-125	406.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,3K7NK@414999|Opitutae	74201|Verrucomicrobia	P	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
YHH3_k127_9444617_3	382464.ABSI01000021_gene421	2.448e-53	189.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia,2IUGB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Nitrogen regulatory protein P-II	-	-	-	-	-	-	-	-	-	-	-	-	P-II
YHH3_k127_9444617_0	382464.ABSI01000020_gene302	0.0	1235.0	COG0525@1|root,COG0525@2|Bacteria,46SGP@74201|Verrucomicrobia,2IU1F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
YHH3_k127_9444617_2	382464.ABSI01000016_gene671	4.5e-69	250.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2.5	-	-	HEAT_2,HEAT_PBS,MFS_1,MFS_2,Peripla_BP_3
YHH3_k127_9451883_0	478741.JAFS01000001_gene1555	1.44e-76	266.0	28I4Y@1|root,2Z88D@2|Bacteria,46VRF@74201|Verrucomicrobia,37GMA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9473615_1	1298865.H978DRAFT_1480	1.843e-77	263.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,4657R@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b0954,iB21_1397.B21_00965,iBWG_1329.BWG_0806,iE2348C_1286.E2348C_0940,iEC042_1314.EC042_1039,iECBD_1354.ECBD_2641,iECB_1328.ECB_00958,iECDH10B_1368.ECDH10B_1024,iECD_1391.ECD_00958,iECED1_1282.ECED1_0977,iECH74115_1262.ECH74115_1118,iECIAI1_1343.ECIAI1_0995,iECIAI39_1322.ECIAI39_2193,iECNA114_1301.ECNA114_1032,iECO103_1326.ECO103_1000,iECO111_1330.ECO111_1022,iECO26_1355.ECO26_1081,iECOK1_1307.ECOK1_1013,iECS88_1305.ECS88_0975,iECSF_1327.ECSF_0868,iECSP_1301.ECSP_1060,iECUMN_1333.ECUMN_1143,iECW_1372.ECW_m1064,iECs_1301.ECs1038,iEKO11_1354.EKO11_2876,iETEC_1333.ETEC_1024,iEcE24377_1341.EcE24377A_1068,iEcHS_1320.EcHS_A1063,iEcSMS35_1347.EcSMS35_2166,iEcolC_1368.EcolC_2642,iG2583_1286.G2583_1189,iJO1366.b0954,iJR904.b0954,iLF82_1304.LF82_0604,iSBO_1134.SBO_2277,iSDY_1059.SDY_0927,iSF_1195.SF0954,iSSON_1240.SSON_0958,iSbBS512_1146.SbBS512_E2362,iUMNK88_1353.UMNK88_1108,iWFL_1372.ECW_m1064,iY75_1357.Y75_RS04955,iZ_1308.Z1304,ic_1306.c1090	FabA
YHH3_k127_9473615_0	583355.Caka_0651	1.197e-209	669.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,46UJK@74201|Verrucomicrobia,3K9E7@414999|Opitutae	414999|Opitutae	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
YHH3_k127_9474413_1	32057.KB217478_gene2161	3.858e-17	86.0	COG1724@1|root,COG1724@2|Bacteria,1G91K@1117|Cyanobacteria,1HPXX@1161|Nostocales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
YHH3_k127_9474413_0	382464.ABSI01000005_gene1037	1.088e-155	516.0	COG1450@1|root,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,2ITGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Bacterial type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
YHH3_k127_9481284_4	452637.Oter_2438	2.542e-75	263.0	COG4166@1|root,COG4166@2|Bacteria,46ZJQ@74201|Verrucomicrobia,3K79R@414999|Opitutae	414999|Opitutae	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
YHH3_k127_9481284_1	1123248.KB893370_gene5155	6.141e-208	658.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1IPV0@117747|Sphingobacteriia	976|Bacteroidetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
YHH3_k127_9481284_0	518766.Rmar_2190	3.739e-210	664.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes,1FJ6T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41,1.1.1.42,1.1.1.85	ko:K00030,ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00709,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YHH3_k127_9481284_3	583355.Caka_2954	2.278e-103	346.0	COG0547@1|root,COG0547@2|Bacteria,46SQA@74201|Verrucomicrobia,3K7TG@414999|Opitutae	414999|Opitutae	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
YHH3_k127_9481284_2	794903.OPIT5_28335	4.901e-108	366.0	COG1109@1|root,COG1109@2|Bacteria,46SJ2@74201|Verrucomicrobia,3K7CB@414999|Opitutae	414999|Opitutae	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YHH3_k127_9481284_5	1191523.MROS_0703	7.081e-74	254.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	hisN	-	3.1.3.15,3.1.3.25,3.1.3.93	ko:K01092,ko:K05602,ko:K18649	ko00053,ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00053,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00114,M00131	R01185,R01186,R01187,R03013,R07674	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YHH3_k127_9485871_0	452637.Oter_3498	1.487e-147	475.0	COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,3K794@414999|Opitutae	414999|Opitutae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH3_k127_9485871_1	382464.ABSI01000022_gene490	1.094e-42	163.0	COG2890@1|root,COG2890@2|Bacteria,46SZE@74201|Verrucomicrobia,2IU5P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
YHH3_k127_9498742_2	631362.Thi970DRAFT_00836	1.408e-40	162.0	COG0642@1|root,COG2205@2|Bacteria,1RF79@1224|Proteobacteria,1SNRK@1236|Gammaproteobacteria,1X0NK@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YHH3_k127_9498742_0	583355.Caka_1147	3.94e-115	378.0	COG0152@1|root,COG0152@2|Bacteria,46SIP@74201|Verrucomicrobia,3K7AD@414999|Opitutae	414999|Opitutae	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
YHH3_k127_9498742_1	536227.CcarbDRAFT_0435	4.932e-112	370.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,36DNK@31979|Clostridiaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH3_k127_9510307_3	452637.Oter_3368	5.186e-160	512.0	COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,3K72I@414999|Opitutae	414999|Opitutae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
YHH3_k127_9510307_9	278957.ABEA03000100_gene913	4.521e-57	204.0	COG1943@1|root,COG1943@2|Bacteria,46XEX@74201|Verrucomicrobia,3K9MH@414999|Opitutae	414999|Opitutae	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	-
YHH3_k127_9510307_2	583355.Caka_2596	6.198e-231	720.0	COG0213@1|root,COG0213@2|Bacteria,46TUU@74201|Verrucomicrobia,3K74X@414999|Opitutae	414999|Opitutae	F	pyrimidine-nucleoside phosphorylase	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
YHH3_k127_9510307_7	794903.OPIT5_23755	1.961e-90	306.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,3K7IJ@414999|Opitutae	414999|Opitutae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
YHH3_k127_9510307_0	382464.ABSI01000012_gene2136	0.0	1013.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,2ITYS@203494|Verrucomicrobiae	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
YHH3_k127_9510307_4	583355.Caka_0678	3.58e-149	504.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,46SKY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
YHH3_k127_9510307_6	583355.Caka_0679	1.572e-94	317.0	COG1305@1|root,COG1305@2|Bacteria,46SQU@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
YHH3_k127_9510307_8	1127673.GLIP_0329	5.227e-68	242.0	COG1305@1|root,COG1305@2|Bacteria,1MVAG@1224|Proteobacteria,1RMXM@1236|Gammaproteobacteria,4664M@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
YHH3_k127_9510307_1	583355.Caka_1258	1.41e-232	727.0	COG2308@1|root,COG2308@2|Bacteria,46TR2@74201|Verrucomicrobia,3K7Q4@414999|Opitutae	414999|Opitutae	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
YHH3_k127_9510307_5	583355.Caka_1257	2.259e-116	383.0	COG2307@1|root,COG2307@2|Bacteria,46S7Q@74201|Verrucomicrobia,3K7VZ@414999|Opitutae	414999|Opitutae	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
YHH3_k127_9546317_1	452637.Oter_2368	2.639e-202	658.0	COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia,3K7BA@414999|Opitutae	414999|Opitutae	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH3_k127_9546317_2	794903.OPIT5_04965	4.076e-41	155.0	2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia,3K87A@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9546317_0	583355.Caka_2039	0.0	1047.0	COG0249@1|root,COG0249@2|Bacteria,46SCK@74201|Verrucomicrobia,3K7NX@414999|Opitutae	414999|Opitutae	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
YHH3_k127_9574961_6	180281.CPCC7001_1766	3.407e-07	57.0	COG0023@1|root,COG0023@2|Bacteria,1G6P3@1117|Cyanobacteria,22TTI@167375|Cyanobium	1117|Cyanobacteria	J	Translation initiation factor SUI1	sui1	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
YHH3_k127_9574961_5	1184267.A11Q_781	4.398e-15	85.0	2EQTX@1|root,33IDK@2|Bacteria,1NJ7Q@1224|Proteobacteria,42XE5@68525|delta/epsilon subdivisions,2WTE3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SirB
YHH3_k127_9574961_4	452637.Oter_3852	4.146e-24	106.0	COG1254@1|root,COG1254@2|Bacteria,46W9W@74201|Verrucomicrobia,3K8DW@414999|Opitutae	414999|Opitutae	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YHH3_k127_9574961_3	583355.Caka_2644	2.568e-36	146.0	2BXAM@1|root,2ZPRA@2|Bacteria,46VTF@74201|Verrucomicrobia,3K81N@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9574961_1	566466.NOR53_304	1.819e-160	511.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,1RMH8@1236|Gammaproteobacteria,1J6DT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	transport system, permease component	yejB	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
YHH3_k127_9574961_2	566466.NOR53_52	8.753e-147	475.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,1J7FF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	yejE	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
YHH3_k127_9574961_0	314285.KT71_00425	2.742e-179	578.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1J88U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
YHH3_k127_9595529_6	452637.Oter_4031	4.462e-45	169.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,46V5S@74201|Verrucomicrobia,3K7YH@414999|Opitutae	414999|Opitutae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
YHH3_k127_9595529_9	452637.Oter_1533	3.803e-13	82.0	COG5074@1|root,COG5074@2|Bacteria,46XTA@74201|Verrucomicrobia,3K7YA@414999|Opitutae	414999|Opitutae	U	SNAP receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9595529_4	497964.CfE428DRAFT_5005	1.196e-91	317.0	COG2202@1|root,COG2208@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,COG5002@2|Bacteria,46U96@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_3,PAS_4,SpoIIE
YHH3_k127_9595529_0	240016.ABIZ01000001_gene3846	1.048e-175	554.0	COG0174@1|root,COG0174@2|Bacteria,46S5C@74201|Verrucomicrobia,2ITKG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glutamine synthetase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Gln-synt_C,Gln-synt_N
YHH3_k127_9595529_5	382464.ABSI01000005_gene1181	3.089e-47	177.0	COG3642@1|root,COG3642@2|Bacteria,46ST7@74201|Verrucomicrobia,2IUME@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	lipopolysaccharide core region biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9595529_2	382464.ABSI01000005_gene1182	1.154e-97	326.0	COG0631@1|root,COG0631@2|Bacteria,46UCG@74201|Verrucomicrobia,2IWMM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
YHH3_k127_9595529_1	278957.ABEA03000041_gene2195	2.338e-116	389.0	COG0304@1|root,COG0304@2|Bacteria,46UQ4@74201|Verrucomicrobia,3K78C@414999|Opitutae	414999|Opitutae	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YHH3_k127_9595529_10	452637.Oter_4016	8.114e-09	61.0	COG0236@1|root,COG0764@1|root,COG0236@2|Bacteria,COG0764@2|Bacteria,46XU4@74201|Verrucomicrobia,3K848@414999|Opitutae	414999|Opitutae	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
YHH3_k127_9595529_3	1203611.KB894543_gene1819	1.549e-92	321.0	COG1032@1|root,COG1032@2|Bacteria,4NKFV@976|Bacteroidetes	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YHH3_k127_9595529_7	118161.KB235919_gene6156	4.667e-44	173.0	COG0251@1|root,COG0251@2|Bacteria,1GC91@1117|Cyanobacteria	1117|Cyanobacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9595529_8	478741.JAFS01000001_gene1830	1.864e-25	113.0	COG0318@1|root,COG0318@2|Bacteria,46T7I@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
YHH3_k127_9624210_2	571.MC52_26395	0.0001132	55.0	2AJKJ@1|root,31A7N@2|Bacteria,1NVRX@1224|Proteobacteria,1SNZ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9624210_1	118166.JH976537_gene4708	2.076e-30	126.0	2BK9M@1|root,32EPT@2|Bacteria,1G703@1117|Cyanobacteria,1HFPS@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9624210_0	911045.PSE_1614	2.382e-34	143.0	COG0297@1|root,COG0297@2|Bacteria,1RH73@1224|Proteobacteria,2UA8P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
YHH3_k127_9624210_3	1506583.JQJY01000005_gene2466	0.0001178	46.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,1I3A8@117743|Flavobacteriia,2NWY8@237|Flavobacterium	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
YHH3_k127_965486_1	452637.Oter_3514	2.357e-55	198.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,3K9H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_965486_0	382464.ABSI01000013_gene1719	4.322e-166	531.0	COG0673@1|root,COG0673@2|Bacteria,46TK3@74201|Verrucomicrobia,2IVGR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_9683344_0	251221.35213566	1.152e-89	321.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9701760_0	382464.ABSI01000011_gene2590	2.985e-156	517.0	COG4773@1|root,COG4773@2|Bacteria,46TH4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_9701760_1	929562.Emtol_3032	4.285e-22	102.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,47JXY@768503|Cytophagia	976|Bacteroidetes	G	Glycoside hydrolase family 16	-	-	3.2.1.73	ko:K01216	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_16
YHH3_k127_971439_0	583355.Caka_1577	1.598e-68	237.0	COG0552@1|root,COG0552@2|Bacteria,46SKC@74201|Verrucomicrobia,3K7EX@414999|Opitutae	414999|Opitutae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
YHH3_k127_971439_3	583355.Caka_1576	8.488e-50	182.0	COG0781@1|root,COG0781@2|Bacteria,46VCF@74201|Verrucomicrobia,3K81J@414999|Opitutae	414999|Opitutae	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
YHH3_k127_971439_4	794903.OPIT5_21485	1.02e-30	128.0	COG0054@1|root,COG0054@2|Bacteria,46T5S@74201|Verrucomicrobia,3K88H@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
YHH3_k127_971439_1	2340.JV46_04910	2.698e-61	223.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
YHH3_k127_971439_2	278957.ABEA03000006_gene4186	2.992e-57	203.0	COG1349@1|root,COG1349@2|Bacteria,46WB4@74201|Verrucomicrobia,3K8E6@414999|Opitutae	414999|Opitutae	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
YHH3_k127_9733363_0	1124780.ANNU01000036_gene41	8.61e-187	606.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,4NFBV@976|Bacteroidetes,47K85@768503|Cytophagia	976|Bacteroidetes	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
YHH3_k127_9737155_0	452637.Oter_0897	8.749e-114	383.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,46S6T@74201|Verrucomicrobia,3K7S6@414999|Opitutae	414999|Opitutae	CO	Disulphide bond corrector protein DsbC	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YHH3_k127_9737155_2	1384484.AEQU_0889	7.34e-74	259.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CVEB@84998|Coriobacteriia	84998|Coriobacteriia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YHH3_k127_9737155_3	1210884.HG799471_gene14681	1.615e-25	123.0	COG0526@1|root,COG0526@2|Bacteria,2J07Q@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YHH3_k127_9737155_1	225849.swp_2111	2.617e-75	285.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,2Q9D0@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	Plug,STN,TonB_dep_Rec
YHH3_k127_9737155_4	1207063.P24_03420	5.141e-17	86.0	COG3712@1|root,COG3712@2|Bacteria,1RHFD@1224|Proteobacteria,2U9ER@28211|Alphaproteobacteria,2JTC5@204441|Rhodospirillales	204441|Rhodospirillales	PT	FecR protein	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
YHH3_k127_9748215_4	382464.ABSI01000011_gene2309	6.608e-38	144.0	COG0640@1|root,COG0640@2|Bacteria,46W0M@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
YHH3_k127_9748215_0	382464.ABSI01000011_gene2310	1.1e-205	647.0	COG0701@1|root,COG0701@2|Bacteria,46XR1@74201|Verrucomicrobia,2IWEA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
YHH3_k127_9748215_7	382464.ABSI01000011_gene2314	3.569e-28	115.0	COG0526@1|root,COG0526@2|Bacteria,46WVU@74201|Verrucomicrobia	74201|Verrucomicrobia	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
YHH3_k127_9748215_8	584708.Apau_0098	3.405e-26	113.0	2DPAK@1|root,33193@2|Bacteria,3TCGH@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9748215_5	1304885.AUEY01000001_gene3203	1.846e-37	149.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
YHH3_k127_9748215_6	278957.ABEA03000004_gene4516	1.63e-29	128.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
YHH3_k127_9748215_2	382464.ABSI01000010_gene3774	1.7e-65	226.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
YHH3_k127_9748215_1	1123511.KB905843_gene1011	2.858e-148	477.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,4H2KS@909932|Negativicutes	909932|Negativicutes	P	arsenical-resistance protein	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
YHH3_k127_9748215_3	1469557.JSWF01000019_gene306	5.798e-54	194.0	COG4232@1|root,COG4232@2|Bacteria,4NPWP@976|Bacteroidetes,1I23K@117743|Flavobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
YHH3_k127_9748215_9	314278.NB231_16448	1.327e-15	79.0	2DSUP@1|root,33HGU@2|Bacteria	2|Bacteria	-	-	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9776300_0	1408473.JHXO01000011_gene3122	4.486e-133	429.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,2FND3@200643|Bacteroidia	976|Bacteroidetes	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
YHH3_k127_9776300_2	7897.ENSLACP00000013609	1.454e-11	72.0	2CMS1@1|root,2QRMG@2759|Eukaryota,38E86@33154|Opisthokonta,3BK5F@33208|Metazoa,3CW0R@33213|Bilateria,487ZI@7711|Chordata,48XSR@7742|Vertebrata	33208|Metazoa	T	procollagen C-endopeptidase enhancer	PCOLCE2	GO:0003674,GO:0005488,GO:0005518,GO:0005539,GO:0008047,GO:0008150,GO:0008201,GO:0009893,GO:0009987,GO:0010033,GO:0010604,GO:0010952,GO:0016504,GO:0019222,GO:0030162,GO:0030234,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0034097,GO:0042221,GO:0043085,GO:0043167,GO:0043168,GO:0044093,GO:0044877,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051716,GO:0052547,GO:0060255,GO:0061134,GO:0065007,GO:0065009,GO:0070887,GO:0071310,GO:0071345,GO:0080090,GO:0097367,GO:0098772,GO:1901681,GO:1990823,GO:1990830	-	-	-	-	-	-	-	-	-	-	CUB,NTR
YHH3_k127_9776300_1	1499967.BAYZ01000173_gene5813	1.346e-30	127.0	COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria	2|Bacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FecR,VIT,VWA,VWA_3
YHH3_k127_9786467_0	743836.AYNA01000017_gene2715	1.366e-55	221.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWK2@28211|Alphaproteobacteria,3700W@31993|Methylocystaceae	28211|Alphaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
YHH3_k127_9801691_0	589865.DaAHT2_2431	9.112e-248	770.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2X5QK@28221|Deltaproteobacteria,2MPFP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
YHH3_k127_9802822_0	452637.Oter_2071	3.114e-165	526.0	COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia,3K7EE@414999|Opitutae	414999|Opitutae	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
YHH3_k127_9802822_1	794903.OPIT5_28550	5.501e-89	306.0	COG1622@1|root,COG3474@1|root,COG1622@2|Bacteria,COG3474@2|Bacteria,46W3S@74201|Verrucomicrobia,3K7PR@414999|Opitutae	414999|Opitutae	C	Cytochrome c oxidase subunit	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
YHH3_k127_9802822_2	583355.Caka_0658	3.826e-68	239.0	COG0109@1|root,COG0109@2|Bacteria,46SQE@74201|Verrucomicrobia,3K7Y2@414999|Opitutae	414999|Opitutae	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
YHH3_k127_9807328_0	452637.Oter_1537	6.559e-136	438.0	COG0667@1|root,COG0667@2|Bacteria,46UF5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YHH3_k127_9807328_1	382464.ABSI01000010_gene3367	3.383e-85	305.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia,2IVM0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
YHH3_k127_9841302_2	472759.Nhal_2632	6.837e-15	76.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1WXIX@135613|Chromatiales	135613|Chromatiales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YHH3_k127_9841302_0	382464.ABSI01000021_gene359	5.908e-85	297.0	COG1253@1|root,COG1253@2|Bacteria,46SMD@74201|Verrucomicrobia,2IU23@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
YHH3_k127_9841302_1	583355.Caka_2434	2.378e-51	193.0	COG0457@1|root,COG0457@2|Bacteria,46XMJ@74201|Verrucomicrobia,3K7KN@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9861016_1	452637.Oter_0678	1.469e-40	156.0	COG0788@1|root,COG0788@2|Bacteria,46SMH@74201|Verrucomicrobia,3K78Z@414999|Opitutae	414999|Opitutae	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
YHH3_k127_9861016_0	382464.ABSI01000012_gene2221	0.0	1598.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,2IU2N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YHH3_k127_9866754_4	743719.PaelaDRAFT_4077	1.156e-41	161.0	COG3291@1|root,COG5434@1|root,COG3291@2|Bacteria,COG5434@2|Bacteria,1UWBV@1239|Firmicutes,4I2E0@91061|Bacilli,26W7A@186822|Paenibacillaceae	91061|Bacilli	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C
YHH3_k127_9866754_0	1121859.KB890738_gene3196	4.537e-175	563.0	COG3408@1|root,COG3408@2|Bacteria,4NGV6@976|Bacteroidetes,47N7I@768503|Cytophagia	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Trehalase
YHH3_k127_9866754_1	926556.Echvi_0934	2.148e-128	426.0	COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9866754_2	344747.PM8797T_16148	5.784e-53	201.0	COG1609@1|root,COG1609@2|Bacteria,2J45S@203682|Planctomycetes	203682|Planctomycetes	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
YHH3_k127_9866754_3	401053.AciPR4_2818	1.894e-46	178.0	COG0591@1|root,COG0591@2|Bacteria,3Y6NZ@57723|Acidobacteria,2JMN0@204432|Acidobacteriia	204432|Acidobacteriia	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YHH3_k127_987397_0	1185876.BN8_03288	1.212e-115	377.0	COG1028@1|root,COG1028@2|Bacteria,4NHVK@976|Bacteroidetes,47K2F@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YHH3_k127_987397_1	382464.ABSI01000002_gene4332	3.297e-25	117.0	COG1266@1|root,COG1266@2|Bacteria,46WKN@74201|Verrucomicrobia,2IUVF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
YHH3_k127_9886487_1	278957.ABEA03000133_gene1600	7.104e-39	154.0	COG0424@1|root,COG0424@2|Bacteria,46VD8@74201|Verrucomicrobia,3K804@414999|Opitutae	414999|Opitutae	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
YHH3_k127_9886487_0	583355.Caka_2484	3.886e-92	312.0	COG1082@1|root,COG1082@2|Bacteria,46SWH@74201|Verrucomicrobia,3K7G6@414999|Opitutae	414999|Opitutae	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YHH3_k127_9886487_3	452637.Oter_2093	2.595e-21	95.0	COG0828@1|root,COG0828@2|Bacteria,46WBR@74201|Verrucomicrobia,3K8F7@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
YHH3_k127_9886487_2	278957.ABEA03000007_gene3496	3.826e-26	109.0	COG0542@1|root,COG0542@2|Bacteria,46S4S@74201|Verrucomicrobia,3K798@414999|Opitutae	414999|Opitutae	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH3_k127_9903094_0	313606.M23134_05906	1.496e-05	59.0	COG1404@1|root,COG4447@1|root,COG4733@1|root,COG4935@1|root,COG5184@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,COG5184@2|Bacteria,4NEJ8@976|Bacteroidetes,47N4Z@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	MAM,TIG,fn3
YHH3_k127_9906487_1	335543.Sfum_2378	2.717e-205	644.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2WKAN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
YHH3_k127_9906487_2	335543.Sfum_2377	3.172e-193	610.0	COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,42NVH@68525|delta/epsilon subdivisions,2WJN9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
YHH3_k127_9906487_0	335543.Sfum_2376	2.048e-249	773.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,42PUK@68525|delta/epsilon subdivisions,2WIN4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
YHH3_k127_9921086_2	452637.Oter_3143	2.056e-45	175.0	COG1105@1|root,COG1105@2|Bacteria,46SED@74201|Verrucomicrobia,3K8AW@414999|Opitutae	414999|Opitutae	H	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
YHH3_k127_9921086_0	583355.Caka_1066	2.2e-322	997.0	COG0365@1|root,COG0365@2|Bacteria,46SBX@74201|Verrucomicrobia,3K77V@414999|Opitutae	414999|Opitutae	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YHH3_k127_9921086_1	382464.ABSI01000005_gene1186	8.76e-79	272.0	COG0809@1|root,COG0809@2|Bacteria,46SDA@74201|Verrucomicrobia,2IU22@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
YHH3_k127_9922303_2	1132442.KB889752_gene709	4.898e-26	111.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1ZD3R@1386|Bacillus	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
YHH3_k127_9922303_1	583355.Caka_2365	1.952e-119	397.0	COG5000@1|root,COG5000@2|Bacteria,46S9Q@74201|Verrucomicrobia,3K7S4@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
YHH3_k127_9922303_0	794903.OPIT5_04165	2.102e-219	689.0	COG0427@1|root,COG0427@2|Bacteria,46TQC@74201|Verrucomicrobia,3K7AC@414999|Opitutae	414999|Opitutae	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
YHH3_k127_9922765_1	305900.GV64_21730	9.445e-25	113.0	COG0591@1|root,COG0591@2|Bacteria,1MW6E@1224|Proteobacteria,1RXYK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YHH3_k127_9922765_0	382464.ABSI01000016_gene739	3.524e-121	430.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
YHH3_k127_9958971_3	452637.Oter_2787	1.538e-77	269.0	COG0739@1|root,COG0739@2|Bacteria,46V20@74201|Verrucomicrobia,3K74E@414999|Opitutae	414999|Opitutae	M	Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH3_k127_9958971_2	583355.Caka_2975	1.008e-87	304.0	2DRTQ@1|root,32URN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9958971_0	583355.Caka_2976	7.167e-157	500.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,3K7P4@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
YHH3_k127_9958971_9	794903.OPIT5_01065	5.428e-29	127.0	COG0457@1|root,COG0457@2|Bacteria,46Z69@74201|Verrucomicrobia,3K8AP@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9958971_7	583355.Caka_1272	8.302e-50	183.0	COG0735@1|root,COG0735@2|Bacteria,46V9Y@74201|Verrucomicrobia,3K81W@414999|Opitutae	414999|Opitutae	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YHH3_k127_9958971_11	794903.OPIT5_16305	1.551e-08	63.0	295DN@1|root,2ZSRI@2|Bacteria,46WWE@74201|Verrucomicrobia,3K80Z@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9958971_6	583355.Caka_1855	6.336e-54	194.0	COG1327@1|root,COG1327@2|Bacteria,46VCN@74201|Verrucomicrobia,3K7XU@414999|Opitutae	414999|Opitutae	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
YHH3_k127_9958971_4	382464.ABSI01000005_gene1332	6.579e-62	217.0	COG0219@1|root,COG0219@2|Bacteria,46SYZ@74201|Verrucomicrobia,2IUCK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	-	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
YHH3_k127_9958971_8	452637.Oter_2719	9.636e-46	169.0	COG0691@1|root,COG0691@2|Bacteria,46VG2@74201|Verrucomicrobia,3K83A@414999|Opitutae	414999|Opitutae	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YHH3_k127_9958971_10	382464.ABSI01000005_gene1329	3.544e-25	106.0	COG1758@1|root,COG1758@2|Bacteria,46W29@74201|Verrucomicrobia,2IUQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	RNA polymerase activity	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
YHH3_k127_9958971_5	452637.Oter_2784	1.237e-59	217.0	2F1X5@1|root,33UWR@2|Bacteria,46V3H@74201|Verrucomicrobia,3K750@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_9958971_1	583355.Caka_1202	2.092e-127	419.0	COG0635@1|root,COG0635@2|Bacteria,46STN@74201|Verrucomicrobia,3K7MM@414999|Opitutae	414999|Opitutae	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
YHH3_k127_9959555_1	1499967.BAYZ01000048_gene2713	3.812e-86	295.0	COG2103@1|root,COG2103@2|Bacteria,2NP6Y@2323|unclassified Bacteria	2|Bacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
YHH3_k127_9959555_6	1449050.JNLE01000003_gene2682	9.679e-24	115.0	COG0300@1|root,COG0300@2|Bacteria,1TRP8@1239|Firmicutes,24DNY@186801|Clostridia,36GC9@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YHH3_k127_9959555_5	696281.Desru_1825	2.67e-31	126.0	COG3603@1|root,COG3603@2|Bacteria,1V9Y8@1239|Firmicutes,24JKN@186801|Clostridia,2663Q@186807|Peptococcaceae	186801|Clostridia	S	ACT domain	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
YHH3_k127_9959555_4	583355.Caka_2055	7.051e-38	153.0	COG0576@1|root,COG0576@2|Bacteria,46VZ0@74201|Verrucomicrobia,3K81S@414999|Opitutae	414999|Opitutae	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YHH3_k127_9959555_0	382464.ABSI01000010_gene3750	3.153e-157	505.0	COG0484@1|root,COG0484@2|Bacteria,46TKC@74201|Verrucomicrobia,2ITUR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH3_k127_9959555_2	452637.Oter_1673	2.308e-77	263.0	COG0299@1|root,COG0299@2|Bacteria,46SS6@74201|Verrucomicrobia,3K74U@414999|Opitutae	414999|Opitutae	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
YHH3_k127_9959555_3	452637.Oter_1674	2.418e-52	193.0	COG2264@1|root,COG2264@2|Bacteria,46SYY@74201|Verrucomicrobia,3K733@414999|Opitutae	414999|Opitutae	J	L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
## 2205 queries scanned
## Total time (seconds): 10.955337524414062
## Rate: 201.27 q/s