## Fri Feb 20 07:35:27 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/YHH3_bin.85.fa -m mmseqs --output YHH3_bin.85 --output_dir /data/result/bins/wyx/eggqs50+/YHH3_bin.85 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YHH3_k127_10035089_1	1120970.AUBZ01000026_gene2121	8.573e-74	258.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,465I5@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045261,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902600	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658	ATP-synt_ab,ATP-synt_ab_N
YHH3_k127_10035089_3	760142.Hipma_0995	7.672e-05	54.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2WJ6I@28221|Deltaproteobacteria,2M6GJ@213113|Desulfurellales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
YHH3_k127_10035089_0	633697.EubceDRAFT1_0611	4.576e-88	308.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,25V5E@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
YHH3_k127_10035089_2	525257.HMPREF0204_10397	1.551e-06	57.0	COG5295@1|root,COG5295@2|Bacteria,4NTMP@976|Bacteroidetes,1I4NQ@117743|Flavobacteriia,3ZPHH@59732|Chryseobacterium	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major
YHH3_k127_10056926_0	1121405.dsmv_2581	1.939e-63	235.0	COG0582@1|root,COG0582@2|Bacteria,1REKP@1224|Proteobacteria,42S9N@68525|delta/epsilon subdivisions,2WNI9@28221|Deltaproteobacteria,2MN9J@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YHH3_k127_10056926_1	933262.AXAM01000006_gene1842	1.443e-21	96.0	2AKQ6@1|root,2ZAYQ@2|Bacteria,1R429@1224|Proteobacteria,42NWN@68525|delta/epsilon subdivisions,2WMKI@28221|Deltaproteobacteria,2MHZS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
YHH3_k127_10606679_1	394503.Ccel_1947	1.616e-91	308.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,36FA9@31979|Clostridiaceae	186801|Clostridia	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YHH3_k127_10606679_2	387092.NIS_0278	5.144e-24	104.0	COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria,43B6G@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YHH3_k127_10606679_0	387631.Asulf_01270	6.057e-100	334.0	COG1948@1|root,arCOG02284@2157|Archaea,2XT7B@28890|Euryarchaeota,245S0@183980|Archaeoglobi	183980|Archaeoglobi	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
YHH3_k127_10702171_2	1229780.BN381_420032	7.108e-26	119.0	COG1477@1|root,COG1477@2|Bacteria,2H8YU@201174|Actinobacteria,3UWYP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
YHH3_k127_10702171_6	867845.KI911784_gene2835	2.923e-05	55.0	COG4097@1|root,COG4097@2|Bacteria,2G71Y@200795|Chloroflexi,375FI@32061|Chloroflexia	32061|Chloroflexia	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
YHH3_k127_10702171_5	40571.JOEA01000003_gene3621	8.922e-06	53.0	COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria,4E428@85010|Pseudonocardiales	201174|Actinobacteria	S	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
YHH3_k127_10702171_0	111781.Lepto7376_3200	1.257e-176	580.0	COG2217@1|root,COG2217@2|Bacteria,1G0JR@1117|Cyanobacteria,1H9J4@1150|Oscillatoriales	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	pacS	GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
YHH3_k127_10702171_1	1304874.JAFY01000002_gene299	7.78e-64	237.0	COG2836@1|root,COG4633@1|root,COG2836@2|Bacteria,COG4633@2|Bacteria	2|Bacteria	K	Biogenesis protein	silP	-	1.9.3.1,3.6.3.54	ko:K02275,ko:K09792,ko:K17686	ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016	M00155	R00081,R00086	RC00002,RC00016	ko00000,ko00001,ko00002,ko01000	3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,DsbD_2,Ferric_reduct,HMA
YHH3_k127_10702171_3	1108045.GORHZ_125_00870	3.247e-10	64.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4GEK3@85026|Gordoniaceae	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
YHH3_k127_10702171_4	1461694.ATO9_05435	4.928e-09	67.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2TQTD@28211|Alphaproteobacteria,2PCQ7@252301|Oceanicola	28211|Alphaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
YHH3_k127_10934619_5	167539.Pro_1266	6.67e-25	112.0	2DMQB@1|root,32SZR@2|Bacteria	2|Bacteria	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
YHH3_k127_10934619_1	273068.TTE0062	8.707e-67	251.0	COG2152@1|root,COG2152@2|Bacteria,1TYI2@1239|Firmicutes,25DIW@186801|Clostridia,42FUJ@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM glycosidase PH1107-related	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
YHH3_k127_10934619_3	1249975.JQLP01000005_gene2065	6.59e-37	159.0	COG0662@1|root,COG2152@1|root,COG0662@2|Bacteria,COG2152@2|Bacteria,4PIDW@976|Bacteroidetes,1ICCR@117743|Flavobacteriia,2P7P2@244698|Gillisia	976|Bacteroidetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
YHH3_k127_10934619_2	335541.Swol_1919	3.933e-62	228.0	COG2152@1|root,COG2152@2|Bacteria,1TYI2@1239|Firmicutes,25DIW@186801|Clostridia	186801|Clostridia	G	PFAM glycosidase, PH1107-related	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
YHH3_k127_10934619_4	552811.Dehly_1064	1.977e-35	148.0	COG2222@1|root,COG2222@2|Bacteria,2G8HU@200795|Chloroflexi,34D2X@301297|Dehalococcoidia	301297|Dehalococcoidia	G	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
YHH3_k127_10934619_7	1033733.CAEK01000001_gene210	5.412e-07	60.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,248MW@186801|Clostridia,22H9N@1570339|Peptoniphilaceae	186801|Clostridia	S	Cof-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
YHH3_k127_10934619_0	1449063.JMLS01000007_gene3551	1.182e-67	241.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4HW10@91061|Bacilli,2726X@186822|Paenibacillaceae	91061|Bacilli	E	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain	-	-	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
YHH3_k127_10934619_6	941449.dsx2_0868	6.444e-13	76.0	COG3042@1|root,COG3042@2|Bacteria	2|Bacteria	-	-	ydbJ	-	-	ko:K09712,ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	DUF333
YHH3_k127_11183783_0	525904.Tter_0502	3.384e-120	407.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YHH3_k127_11183783_1	504472.Slin_5205	8.241e-32	136.0	COG2520@1|root,COG2520@2|Bacteria,4NMFM@976|Bacteroidetes,47Y13@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
YHH3_k127_11320005_3	1167006.UWK_01789	9.898e-11	74.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,42QFA@68525|delta/epsilon subdivisions,2WK13@28221|Deltaproteobacteria,2MJRY@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	iAF987.Gmet_1505	Glycos_transf_4
YHH3_k127_11320005_2	1032480.MLP_17940	8.557e-43	175.0	COG1215@1|root,COG1215@2|Bacteria,2IK1V@201174|Actinobacteria	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11320005_1	1304880.JAGB01000002_gene2401	1.473e-54	200.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia	186801|Clostridia	L	hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YHH3_k127_11320005_0	1313265.JNIE01000002_gene867	1.217e-101	346.0	COG0143@1|root,COG0143@2|Bacteria,2G3J0@200783|Aquificae	200783|Aquificae	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
YHH3_k127_11443878_2	697281.Mahau_1940	1.214e-23	106.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,24997@186801|Clostridia,42ETJ@68295|Thermoanaerobacterales	186801|Clostridia	S	G5 domain protein	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
YHH3_k127_11443878_1	1128421.JAGA01000002_gene788	4.309e-38	154.0	COG0030@1|root,COG0030@2|Bacteria,2NPDT@2323|unclassified Bacteria	2|Bacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YHH3_k127_11443878_0	479434.Sthe_1318	2.853e-50	188.0	COG0652@1|root,COG0652@2|Bacteria,2G6RE@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
YHH3_k127_11443878_3	1168034.FH5T_14885	1.16e-20	103.0	COG2348@1|root,COG2348@2|Bacteria,4NJIC@976|Bacteroidetes,2FR4N@200643|Bacteroidia	976|Bacteroidetes	V	FemAB family	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
YHH3_k127_11443878_5	1312959.KI914647_gene188	0.0002144	53.0	COG2348@1|root,COG2348@2|Bacteria,2HURK@201174|Actinobacteria,1W7J3@1268|Micrococcaceae	201174|Actinobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
YHH3_k127_11443878_4	457425.XNR_5175	9.558e-13	73.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria	201174|Actinobacteria	L	RecB family exonuclease	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
YHH3_k127_11657456_1	1047013.AQSP01000139_gene2394	9.931e-85	288.0	COG0501@1|root,COG0501@2|Bacteria,2NP1V@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	DUF3318,Peptidase_M48
YHH3_k127_11657456_2	552811.Dehly_1038	8.757e-09	61.0	COG0721@1|root,COG0721@2|Bacteria,2G763@200795|Chloroflexi,34DF5@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
YHH3_k127_11657456_0	439235.Dalk_4493	1.92e-133	440.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2MI5B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YHH3_k127_11844692_12	335543.Sfum_2837	2.043e-21	95.0	COG4191@1|root,COG4251@1|root,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria,42QA2@68525|delta/epsilon subdivisions,2X7QC@28221|Deltaproteobacteria,2MQRX@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE3,PAS_9
YHH3_k127_11844692_4	1511.CLOST_0668	1.481e-40	156.0	COG4852@1|root,COG4852@2|Bacteria,1VBU5@1239|Firmicutes,24Q4S@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
YHH3_k127_11844692_10	665571.STHERM_c14910	5.574e-29	121.0	COG5274@1|root,COG5274@2|Bacteria	2|Bacteria	C	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5,FA_desaturase
YHH3_k127_11844692_15	1356854.N007_09825	5.844e-13	81.0	COG1287@1|root,COG1287@2|Bacteria,1V7EF@1239|Firmicutes,4IRWR@91061|Bacilli	91061|Bacilli	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_11844692_5	515620.EUBELI_00097	9.425e-40	162.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,25VPT@186806|Eubacteriaceae	186801|Clostridia	M	Mannose-6-phosphate isomerase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
YHH3_k127_11844692_14	1300350.DSW25_03190	1.806e-13	74.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,3ZXAC@60136|Sulfitobacter	28211|Alphaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
YHH3_k127_11844692_2	293826.Amet_2994	7.599e-94	330.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,36FK8@31979|Clostridiaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
YHH3_k127_11844692_0	1308866.J416_05778	2.527e-120	399.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,47000@74385|Gracilibacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YHH3_k127_11844692_16	929712.KI912613_gene4225	5.357e-10	72.0	COG1807@1|root,COG1807@2|Bacteria,2HNIC@201174|Actinobacteria,4CPHR@84995|Rubrobacteria	84995|Rubrobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_11844692_3	523845.AQXV01000053_gene672	2.033e-62	231.0	COG0166@1|root,arCOG00052@2157|Archaea,2XTFF@28890|Euryarchaeota,23QEC@183939|Methanococci	183939|Methanococci	G	PFAM phosphoglucose isomerase (PGI)	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0016853,GO:0016860,GO:0016861	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
YHH3_k127_11844692_9	203119.Cthe_3180	5.988e-31	132.0	2EU2Z@1|root,33MJU@2|Bacteria	2|Bacteria	H	Ribosomal RNA methyltransferase (FmrO)	-	-	2.1.1.179	ko:K18845	-	-	-	-	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	FmrO
YHH3_k127_11844692_11	1449063.JMLS01000007_gene3568	8.101e-22	109.0	COG0265@1|root,COG0265@2|Bacteria,1TVC9@1239|Firmicutes,4HCH7@91061|Bacilli,26RY5@186822|Paenibacillaceae	91061|Bacilli	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YHH3_k127_11844692_6	81824.XP_001750680.1	2.228e-39	152.0	2DZD8@1|root,2S6XN@2759|Eukaryota,3ACAN@33154|Opisthokonta	33154|Opisthokonta	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
YHH3_k127_11844692_1	515635.Dtur_0462	5.79e-98	333.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	bglB	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
YHH3_k127_11844692_8	304371.MCP_0287	1.805e-37	157.0	COG3174@1|root,arCOG04203@2157|Archaea,2XT0W@28890|Euryarchaeota,2N9ST@224756|Methanomicrobia	224756|Methanomicrobia	P	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
YHH3_k127_11844692_13	1121428.DESHY_110224___1	3.056e-15	89.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,2601U@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Cu_amine_oxidN1,PDZ,PDZ_2,Peptidase_S41
YHH3_k127_11881246_3	1121324.CLIT_11c02360	6.888e-114	384.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
YHH3_k127_11881246_8	555079.Toce_1232	5.558e-25	106.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,42GTG@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
YHH3_k127_11881246_0	697281.Mahau_1041	6.486e-176	576.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,42F53@68295|Thermoanaerobacterales	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YHH3_k127_11881246_5	246194.CHY_0330	1.524e-81	284.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,42FKN@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YHH3_k127_11881246_6	255470.cbdbA391	3.128e-50	186.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi,34CY0@301297|Dehalococcoidia	301297|Dehalococcoidia	L	UreE urease accessory protein, C-terminal domain	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YHH3_k127_11881246_2	397288.C806_02511	3.225e-127	426.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,27J7N@186928|unclassified Lachnospiraceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
YHH3_k127_11881246_1	635013.TherJR_1406	3.101e-133	453.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,260AY@186807|Peptococcaceae	186801|Clostridia	D	DNA segregation ATPase FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YHH3_k127_11881246_9	635013.TherJR_1418	1.487e-07	61.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,261QR@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
YHH3_k127_11881246_4	311424.DhcVS_509	2.751e-91	307.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,34CN2@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH3_k127_11881246_7	545243.BAEV01000046_gene3634	2.121e-40	155.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,36DF4@31979|Clostridiaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH3_k127_12124647_4	413816.BBJP01000013_gene1003	9.235e-33	135.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,23S93@183963|Halobacteria	183963|Halobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
YHH3_k127_12124647_0	309801.trd_0965	8.167e-105	354.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia	189775|Thermomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YHH3_k127_12124647_8	986075.CathTA2_2514	4.009e-21	98.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli	91061|Bacilli	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
YHH3_k127_12124647_3	1089548.KI783301_gene3366	3.898e-40	154.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,3WEIQ@539002|Bacillales incertae sedis	91061|Bacilli	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
YHH3_k127_12124647_5	1408433.JHXV01000034_gene39	6.668e-30	122.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,1I2S3@117743|Flavobacteriia,2PB15@246874|Cryomorphaceae	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
YHH3_k127_12124647_1	881621.LIV_2528	1.371e-56	202.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,26JUC@186820|Listeriaceae	91061|Bacilli	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
YHH3_k127_12124647_7	595460.RRSWK_06887	2.146e-23	104.0	COG0096@1|root,COG0096@2|Bacteria,2IZ8I@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
YHH3_k127_12124647_9	944481.JAFP01000001_gene1466	4.065e-19	87.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,2M7GG@213113|Desulfurellales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
YHH3_k127_12124647_2	1274524.BSONL12_22049	7.06e-49	180.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,1ZB6T@1386|Bacillus	91061|Bacilli	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
YHH3_k127_12124647_6	1158607.UAU_01424	4.053e-29	119.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,4B2Y9@81852|Enterococcaceae	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
YHH3_k127_1213192_1	1123009.AUID01000003_gene1884	1.968e-45	170.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,26CIM@186813|unclassified Clostridiales	186801|Clostridia	M	MobA-like NTP transferase domain	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N,NTP_transferase
YHH3_k127_1213192_3	1226322.HMPREF1545_04039	1.095e-08	63.0	COG1652@1|root,COG1652@2|Bacteria,1V1BA@1239|Firmicutes,24MKW@186801|Clostridia	186801|Clostridia	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
YHH3_k127_1213192_0	387092.NIS_1287	1.99e-129	435.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2YNK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
YHH3_k127_1213192_2	386456.JQKN01000015_gene2945	1.575e-36	141.0	COG1704@1|root,arCOG04574@2157|Archaea,2XXB9@28890|Euryarchaeota,23PHV@183925|Methanobacteria	183925|Methanobacteria	S	PFAM LemA	-	-	-	-	-	-	-	-	-	-	-	-	LemA
YHH3_k127_1234303_0	1048834.TC41_1649	1.145e-50	192.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,277XE@186823|Alicyclobacillaceae	91061|Bacilli	D	Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH3_k127_1234303_2	938293.CAJU020000016_gene1730	5.464e-42	159.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,22GFG@1570339|Peptoniphilaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
YHH3_k127_1234303_1	123214.PERMA_0079	1.966e-46	175.0	COG0217@1|root,COG0217@2|Bacteria,2G3N5@200783|Aquificae	200783|Aquificae	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
YHH3_k127_1234303_3	255470.cbdbA1729	9.374e-05	51.0	COG0457@1|root,COG0457@2|Bacteria,2G6Q2@200795|Chloroflexi,34CXC@301297|Dehalococcoidia	301297|Dehalococcoidia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
YHH3_k127_12516018_0	649761.HMPREF0973_02548	2.747e-113	377.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,2FNF4@200643|Bacteroidia	976|Bacteroidetes	L	ATPase (AAA	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
YHH3_k127_12658855_1	1449126.JQKL01000014_gene2985	2.915e-101	339.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,268B4@186813|unclassified Clostridiales	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
YHH3_k127_12658855_2	649747.HMPREF0083_06036	1.921e-88	301.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,4HD97@91061|Bacilli,26VE7@186822|Paenibacillaceae	91061|Bacilli	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YHH3_k127_12658855_6	326427.Cagg_3081	2.784e-17	89.0	COG1611@1|root,COG1611@2|Bacteria,2G6IB@200795|Chloroflexi,376GG@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YHH3_k127_12658855_5	1305836.AXVE01000004_gene1745	3.978e-20	98.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,26DNF@186818|Planococcaceae	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YHH3_k127_12658855_4	1122182.KB903833_gene5659	5.881e-28	118.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,4DCQE@85008|Micromonosporales	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	rpiB	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005576,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2465c	LacAB_rpiB
YHH3_k127_12658855_3	118163.Ple7327_3216	7.693e-48	181.0	COG0682@1|root,COG0682@2|Bacteria,1G0H2@1117|Cyanobacteria,3VIRF@52604|Pleurocapsales	1117|Cyanobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
YHH3_k127_12658855_7	797114.C475_06130	3.384e-17	85.0	COG4818@1|root,arCOG04344@2157|Archaea,2Y00G@28890|Euryarchaeota,23XT0@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
YHH3_k127_12658855_0	515635.Dtur_0780	5.399e-126	424.0	COG1793@1|root,COG1793@2|Bacteria	2|Bacteria	L	dna ligase	lig	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
YHH3_k127_12799254_2	309799.DICTH_1275	6.147e-08	61.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	TPR_2,TPR_8,Wzy_C
YHH3_k127_12799254_0	203119.Cthe_2690	7.968e-55	203.0	COG0382@1|root,COG0382@2|Bacteria,1TRTB@1239|Firmicutes,24AQ0@186801|Clostridia,3WNTP@541000|Ruminococcaceae	186801|Clostridia	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
YHH3_k127_12871325_1	926550.CLDAP_09830	3.853e-101	344.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi	200795|Chloroflexi	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
YHH3_k127_12871325_3	1203602.HMPREF1527_00164	3.741e-29	125.0	COG0500@1|root,COG0500@2|Bacteria,2I6HE@201174|Actinobacteria,4CW1I@84998|Coriobacteriia	84998|Coriobacteriia	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
YHH3_k127_12871325_2	381764.Fnod_0651	8.615e-32	130.0	COG0335@1|root,COG0335@2|Bacteria,2GD1K@200918|Thermotogae	200918|Thermotogae	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
YHH3_k127_12871325_0	266117.Rxyl_0676	1.384e-227	724.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CU4U@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM UvrB UvrC protein AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YHH3_k127_12871325_4	266117.Rxyl_3166	5.292e-15	79.0	COG0749@1|root,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A,DNA_pol_A_exo1
YHH3_k127_1289198_1	944480.ATUV01000001_gene1708	3.303e-98	325.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2M6MN@213113|Desulfurellales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YHH3_k127_1289198_0	1121024.AUCD01000004_gene1583	1.554e-193	609.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,27F8K@186828|Carnobacteriaceae	91061|Bacilli	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	iSB619.SA_RS02960	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YHH3_k127_1289198_7	574087.Acear_0161	9.892e-37	141.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,3WAR4@53433|Halanaerobiales	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
YHH3_k127_1289198_9	765420.OSCT_0199	1.401e-25	111.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi,375C3@32061|Chloroflexia	32061|Chloroflexia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
YHH3_k127_1289198_4	292459.STH3074	1.333e-50	186.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YHH3_k127_1289198_12	525904.Tter_0717	3.458e-11	67.0	COG0089@1|root,COG0089@2|Bacteria,2NPWC@2323|unclassified Bacteria	2|Bacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
YHH3_k127_1289198_2	1161902.HMPREF0378_1163	5.188e-86	292.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WCDD@538999|Clostridiales incertae sedis	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YHH3_k127_1289198_8	264201.pc0416	2.518e-32	127.0	COG0185@1|root,COG0185@2|Bacteria,2JG8Y@204428|Chlamydiae	204428|Chlamydiae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
YHH3_k127_1289198_10	877411.JMMA01000002_gene2707	7.418e-18	89.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3WJ9K@541000|Ruminococcaceae	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
YHH3_k127_1289198_3	1304284.L21TH_0898	6.212e-62	219.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,36ETZ@31979|Clostridiaceae	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YHH3_k127_1289198_5	56780.SYN_00992	3.327e-49	179.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2WP71@28221|Deltaproteobacteria,2MQGG@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
YHH3_k127_1289198_13	243231.GSU2849	0.0006973	45.0	COG0255@1|root,COG0255@2|Bacteria,1Q1R3@1224|Proteobacteria,42WYX@68525|delta/epsilon subdivisions,2WSTS@28221|Deltaproteobacteria,43VXF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
YHH3_k127_1289198_11	1307834.BARL01000002_gene1146	3.701e-12	69.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2UBRF@28211|Alphaproteobacteria,2JTYK@204441|Rhodospirillales	204441|Rhodospirillales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
YHH3_k127_1289198_6	1121930.AQXG01000022_gene64	7.308e-37	142.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1ISEA@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
YHH3_k127_1576479_0	671143.DAMO_2896	1.442e-187	618.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YHH3_k127_1576479_1	1235803.C825_03569	2.99e-05	48.0	COG1063@1|root,COG1063@2|Bacteria,4PJ8J@976|Bacteroidetes,2FR5Y@200643|Bacteroidia,231HN@171551|Porphyromonadaceae	976|Bacteroidetes	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YHH3_k127_1932950_0	696369.KI912183_gene893	1.499e-91	317.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YHH3_k127_1932950_1	443254.Marpi_1732	2.944e-88	305.0	COG0162@1|root,COG0162@2|Bacteria,2GCKH@200918|Thermotogae	200918|Thermotogae	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iLJ478.TM0478	S4,tRNA-synt_1b
YHH3_k127_1932950_2	1385511.N783_14475	7.36e-46	178.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,2Y8W2@289201|Pontibacillus	91061|Bacilli	M	Penicillin-binding protein	ponA	GO:0005575,GO:0005576	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
YHH3_k127_232812_1	37659.JNLN01000001_gene2396	3.424e-39	160.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,36DEG@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
YHH3_k127_232812_0	555079.Toce_1358	2.102e-110	374.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,42EM9@68295|Thermoanaerobacterales	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
YHH3_k127_2376733_7	1236689.MMALV_10810	7.882e-14	76.0	arCOG03272@1|root,arCOG03272@2157|Archaea,2Y1VM@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	2.7.7.6	ko:K00960	-	-	-	-	ko00000,ko01000	-	-	-	-
YHH3_k127_2376733_10	1278073.MYSTI_01952	2.762e-11	68.0	2DRJA@1|root,33C0M@2|Bacteria,1NBK2@1224|Proteobacteria,433S6@68525|delta/epsilon subdivisions,2WY1T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of Unknown Function with PDB structure (DUF3850)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3850
YHH3_k127_2376733_3	1463917.JODC01000006_gene7962	1.23e-48	181.0	2BU85@1|root,32PHM@2|Bacteria,2IP49@201174|Actinobacteria	201174|Actinobacteria	S	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YHH3_k127_2376733_0	1195236.CTER_0541	4.746e-280	878.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,3WHVU@541000|Ruminococcaceae	186801|Clostridia	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
YHH3_k127_2376733_1	497965.Cyan7822_2288	3.293e-211	666.0	COG0737@1|root,COG0737@2|Bacteria,1GJ13@1117|Cyanobacteria,3KKIN@43988|Cyanothece	1117|Cyanobacteria	F	Belongs to the 5'-nucleotidase family	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Metallophos
YHH3_k127_2376733_8	272562.CA_C0069	3.792e-13	75.0	COG2703@1|root,COG2703@2|Bacteria,1VBEC@1239|Firmicutes,24NV2@186801|Clostridia,36KG0@31979|Clostridiaceae	186801|Clostridia	P	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
YHH3_k127_2376733_9	1382305.AZUC01000046_gene605	1.043e-12	72.0	2EEX1@1|root,338QB@2|Bacteria,1VGA4@1239|Firmicutes,4HPYN@91061|Bacilli,26HTF@186818|Planococcaceae	91061|Bacilli	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
YHH3_k127_2376733_2	237368.SCABRO_01640	1.554e-51	195.0	COG3608@1|root,COG3608@2|Bacteria	237368.SCABRO_01640|-	G	succinylglutamate desuccinylase aspartoacylase	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2376733_4	690850.Desaf_0003	1.171e-40	162.0	COG1351@1|root,COG1351@2|Bacteria,1R6TS@1224|Proteobacteria,43BGP@68525|delta/epsilon subdivisions,2WJ84@28221|Deltaproteobacteria,2MG2I@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
YHH3_k127_2376733_6	255470.cbdbA1100	2.624e-15	81.0	COG0826@1|root,COG0826@2|Bacteria,2GAVB@200795|Chloroflexi,34DF3@301297|Dehalococcoidia	301297|Dehalococcoidia	O	peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_2376733_5	309799.DICTH_0452	1.505e-29	121.0	COG2135@1|root,COG2135@2|Bacteria	2|Bacteria	S	peptidase activity	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
YHH3_k127_2399396_6	273068.TTE1274	1.111e-05	56.0	COG3167@1|root,COG3167@2|Bacteria,1VB5U@1239|Firmicutes,24NVC@186801|Clostridia,42GWM@68295|Thermoanaerobacterales	186801|Clostridia	NU	Pilus assembly protein, PilO	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
YHH3_k127_2399396_0	1031288.AXAA01000001_gene2276	9.265e-60	214.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,36EJ7@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
YHH3_k127_2399396_3	545243.BAEV01000071_gene2702	3.462e-13	72.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,36KGX@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
YHH3_k127_2399396_4	1121865.OMW_01057	1.316e-09	64.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,4B30K@81852|Enterococcaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
YHH3_k127_2399396_1	1123302.KB904155_gene1732	1.76e-52	193.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli	91061|Bacilli	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YHH3_k127_2399396_5	273068.TTE1471	2.837e-08	57.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,42H5S@68295|Thermoanaerobacterales	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
YHH3_k127_2399396_2	316274.Haur_0751	4.341e-21	95.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi,37754@32061|Chloroflexia	32061|Chloroflexia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
YHH3_k127_253440_3	243275.TDE_2073	0.0002295	48.0	COG0457@1|root,COG0457@2|Bacteria,2J5I5@203691|Spirochaetes	203691|Spirochaetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
YHH3_k127_253440_0	929558.SMGD1_0086	1.049e-79	286.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
YHH3_k127_253440_2	1424334.W822_21790	1.375e-36	141.0	COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,2VU1R@28216|Betaproteobacteria,3T3YE@506|Alcaligenaceae	28216|Betaproteobacteria	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YHH3_k127_253440_1	1284352.AOIG01000005_gene2584	4.346e-62	220.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,26RJM@186822|Paenibacillaceae	91061|Bacilli	NU	type II secretion system protein	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH3_k127_2942088_0	880073.Calab_3704	1.081e-73	253.0	COG0016@1|root,COG0016@2|Bacteria,2NNNT@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415,iJN746.PP_2469,iSSON_1240.SSON_1444,iYL1228.KPN_02176	Phe_tRNA-synt_N,tRNA-synt_2d
YHH3_k127_2942088_1	246194.CHY_1570	2.36e-66	250.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,42F4K@68295|Thermoanaerobacterales	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
YHH3_k127_3017002_0	1047013.AQSP01000118_gene1252	2.076e-32	144.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3017002_1	592015.HMPREF1705_00795	0.0008496	48.0	COG1316@1|root,COG1316@2|Bacteria,3TA77@508458|Synergistetes	508458|Synergistetes	K	TIGRFAM cell envelope-related function transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
YHH3_k127_3026715_0	344747.PM8797T_18084	4.51e-211	665.0	COG0719@1|root,COG0719@2|Bacteria,2IXZD@203682|Planctomycetes	203682|Planctomycetes	O	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
YHH3_k127_3026715_4	945713.IALB_2895	2.25e-26	116.0	COG0719@1|root,COG0719@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
YHH3_k127_3026715_1	1131266.ARWQ01000005_gene811	3.113e-130	427.0	COG0520@1|root,arCOG00065@2157|Archaea,41SCV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YHH3_k127_3026715_3	1459636.NTE_02653	1.221e-28	119.0	COG0822@1|root,arCOG02077@2157|Archaea,41SPT@651137|Thaumarchaeota	651137|Thaumarchaeota	C	SUF system FeS assembly protein	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YHH3_k127_3026715_6	1291050.JAGE01000001_gene2399	1.151e-11	67.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia	186801|Clostridia	D	cluster protein-associated redox disulfide domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
YHH3_k127_3026715_5	445961.IW15_03840	6.037e-22	106.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1HYPM@117743|Flavobacteriia,3ZQCP@59732|Chryseobacterium	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YHH3_k127_3026715_7	580327.Tthe_0267	0.0003288	48.0	COG2919@1|root,COG2919@2|Bacteria,1VIN8@1239|Firmicutes,24U23@186801|Clostridia,42HDA@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
YHH3_k127_3026715_2	641491.DND132_1599	1.172e-32	131.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria,2M9JW@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH3_k127_3189696_0	255470.cbdbA1074	1.841e-30	129.0	29B55@1|root,2ZY3K@2|Bacteria,2GAYB@200795|Chloroflexi,34DK2@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_326335_3	1128421.JAGA01000002_gene28	0.0005664	51.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_326335_1	880073.Calab_2791	9.782e-12	77.0	COG0438@1|root,COG0438@2|Bacteria,2NQ5N@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH3_k127_326335_0	326427.Cagg_2762	5.099e-112	370.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
YHH3_k127_326335_2	552811.Dehly_1213	2.408e-06	53.0	COG2211@1|root,COG2211@2|Bacteria,2G8SN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3301969_1	592031.GCWU000322_00198	2.34e-38	153.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25UZC@186806|Eubacteriaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YHH3_k127_3301969_0	227377.CBU_2049	2.246e-103	346.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1JDU1@118969|Legionellales	118969|Legionellales	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YHH3_k127_3329196_10	1408422.JHYF01000002_gene2284	6.16e-18	94.0	COG2414@1|root,COG2414@2|Bacteria,1TT8D@1239|Firmicutes,24A40@186801|Clostridia,36QWA@31979|Clostridiaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
YHH3_k127_3329196_8	1328313.DS2_06621	1.279e-22	106.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,466HI@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
YHH3_k127_3329196_5	867845.KI911784_gene2144	5.927e-34	144.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,3767D@32061|Chloroflexia	32061|Chloroflexia	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
YHH3_k127_3329196_15	552811.Dehly_1505	5.904e-06	56.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi,34D0N@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
YHH3_k127_3329196_13	665950.HMPREF1025_01751	6.707e-10	69.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,27PYQ@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
YHH3_k127_3329196_16	1232666.JANE01000003_gene608	0.0003889	48.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,4GZKB@90964|Staphylococcaceae	91061|Bacilli	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
YHH3_k127_3329196_3	246194.CHY_0409	2.378e-65	244.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,42EMB@68295|Thermoanaerobacterales	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YHH3_k127_3329196_1	941824.TCEL_01994	1.458e-198	635.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,36EZX@31979|Clostridiaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YHH3_k127_3329196_4	1230341.MJ3_13359	4.577e-65	229.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli	91061|Bacilli	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
YHH3_k127_3329196_6	536227.CcarbDRAFT_2269	2.171e-29	126.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,36DW8@31979|Clostridiaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
YHH3_k127_3329196_9	696369.KI912183_gene91	4.817e-20	96.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,26214@186807|Peptococcaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YHH3_k127_3329196_0	479434.Sthe_0714	1.865e-249	785.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi,27Y4Z@189775|Thermomicrobia	189775|Thermomicrobia	O	MreB/Mbl protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YHH3_k127_3329196_14	865938.Weevi_1691	7.504e-07	55.0	COG4980@1|root,COG4980@2|Bacteria,4NXMW@976|Bacteroidetes,1I6Q1@117743|Flavobacteriia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
YHH3_k127_3329196_2	1047013.AQSP01000118_gene1252	9.89e-89	322.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3329196_7	1382306.JNIM01000001_gene244	5.705e-27	124.0	COG0849@1|root,COG0849@2|Bacteria	2|Bacteria	D	cell division	-	-	-	-	-	-	-	-	-	-	-	-	FtsA
YHH3_k127_3329196_11	926561.KB900622_gene689	1.238e-13	84.0	COG3299@1|root,COG3299@2|Bacteria,1VWH4@1239|Firmicutes,2519B@186801|Clostridia,3WBQU@53433|Halanaerobiales	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
YHH3_k127_3329196_12	380749.HY04AAS1_0205	1.685e-11	70.0	COG0816@1|root,COG0816@2|Bacteria,2G4CF@200783|Aquificae	200783|Aquificae	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
YHH3_k127_3355329_0	926550.CLDAP_38190	1.343e-121	403.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH3_k127_3355329_1	1229783.C273_06373	8.71e-31	128.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,4GYG4@90964|Staphylococcaceae	91061|Bacilli	U	Belongs to the peptidase S26 family	spsB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
YHH3_k127_3355329_3	7897.ENSLACP00000013218	2.251e-14	86.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BAFG@33208|Metazoa,3CV6Z@33213|Bilateria,483KS@7711|Chordata,48WWG@7742|Vertebrata	33208|Metazoa	S	Domain of unknown function (DUF1736)	TMTC4	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_17,TPR_2,TPR_8
YHH3_k127_3355329_2	557436.Lreu_0901	2.108e-28	118.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli,3F492@33958|Lactobacillaceae	91061|Bacilli	J	NOL1 NOP2 sun family protein	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
YHH3_k127_3394744_0	926556.Echvi_2564	5.001e-37	148.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,4NEQX@976|Bacteroidetes,47PIJ@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM exonuclease, DNA polymerase III, epsilon subunit family	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
YHH3_k127_3394744_1	880073.Calab_1190	1.425e-06	57.0	COG1514@1|root,COG1514@2|Bacteria,2NPRT@2323|unclassified Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
YHH3_k127_3439042_3	871968.DESME_14395	3.138e-05	53.0	COG3307@1|root,COG3307@2|Bacteria,1U3ZF@1239|Firmicutes,249D2@186801|Clostridia	186801|Clostridia	M	O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YHH3_k127_3439042_2	1224318.DT73_14915	1.768e-17	88.0	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	methylated DNA-protein cysteine methyltransferase	ybaZ	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
YHH3_k127_3439042_4	309799.DICTH_1706	0.0001512	54.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,CBM9_1,PEGA,Peptidase_S9
YHH3_k127_3439042_0	889378.Spiaf_2235	1.528e-140	468.0	COG0013@1|root,COG0013@2|Bacteria,2J5G2@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YHH3_k127_3439042_1	1276920.ADIAG_00669	3.774e-24	103.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,1W9DG@1268|Micrococcaceae	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YHH3_k127_3636495_7	1385514.N782_16745	3.245e-07	57.0	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,4HMDE@91061|Bacilli,2YAJ1@289201|Pontibacillus	91061|Bacilli	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
YHH3_k127_3636495_6	1462526.BN990_03826	1.426e-24	108.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,4C5NX@84406|Virgibacillus	91061|Bacilli	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
YHH3_k127_3636495_10	1229758.C270_01445	0.0004646	47.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,4AX1G@81850|Leuconostocaceae	91061|Bacilli	O	COG1214 Inactive homolog of metal-dependent proteases	yeaZ	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YHH3_k127_3636495_1	1392489.JPOL01000002_gene1265	3.311e-100	336.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1HY26@117743|Flavobacteriia,2XIV9@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
YHH3_k127_3636495_4	59919.PMM1522	1.703e-58	214.0	COG0463@1|root,COG0463@2|Bacteria,1G153@1117|Cyanobacteria,1MKG7@1212|Prochloraceae	1117|Cyanobacteria	M	Alternative locus ID	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
YHH3_k127_3636495_0	1189612.A33Q_1689	2.667e-141	454.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,47JU8@768503|Cytophagia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YHH3_k127_3636495_9	1347087.CBYO010000022_gene3354	0.0001067	52.0	COG0406@1|root,COG0406@2|Bacteria,1V3RC@1239|Firmicutes,4HHSJ@91061|Bacilli	91061|Bacilli	G	Phosphoglycerate mutase	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
YHH3_k127_3636495_3	316274.Haur_3122	9.58e-81	283.0	COG2133@1|root,COG2133@2|Bacteria,2G7VF@200795|Chloroflexi,377AV@32061|Chloroflexia	32061|Chloroflexia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YHH3_k127_3636495_8	1410676.JNKL01000021_gene1131	3.292e-05	49.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YHH3_k127_3636495_2	880072.Desac_0814	2.127e-99	338.0	COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,43DC6@68525|delta/epsilon subdivisions,2X8I6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3636495_5	439481.Aboo_1125	8.645e-54	203.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,3F2QZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Polyprenyl synthetase	idsA	GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
YHH3_k127_3673164_2	370438.PTH_0933	2.915e-09	69.0	COG4632@1|root,COG4632@2|Bacteria,1UCD4@1239|Firmicutes,24EWS@186801|Clostridia,2633V@186807|Peptococcaceae	186801|Clostridia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,NAGPA
YHH3_k127_3673164_0	1291050.JAGE01000001_gene1452	5.411e-50	186.0	COG0566@1|root,COG0566@2|Bacteria,1TS18@1239|Firmicutes,24KJT@186801|Clostridia,3WPK8@541000|Ruminococcaceae	186801|Clostridia	J	SpoU rRNA Methylase family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
YHH3_k127_3673164_1	660470.Theba_1964	1.519e-36	149.0	COG3509@1|root,COG3509@2|Bacteria,2GE8V@200918|Thermotogae	200918|Thermotogae	Q	Putative esterase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
YHH3_k127_3688685_2	944481.JAFP01000001_gene707	9.533e-11	63.0	COG3118@1|root,COG3118@2|Bacteria,1NXN2@1224|Proteobacteria,430GJ@68525|delta/epsilon subdivisions,2WVXE@28221|Deltaproteobacteria,2M79Y@213113|Desulfurellales	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
YHH3_k127_3688685_1	1250232.JQNJ01000001_gene2091	2.18e-19	95.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,1I40T@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
YHH3_k127_3688685_0	373903.Hore_02290	4.092e-176	572.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WAC7@53433|Halanaerobiales	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YHH3_k127_3688685_3	649639.Bcell_0040	4.838e-07	58.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1ZC0Q@1386|Bacillus	91061|Bacilli	T	protein conserved in bacteria	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
YHH3_k127_3741275_0	1121091.AUMP01000001_gene64	2.41e-26	118.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4HBBF@91061|Bacilli	91061|Bacilli	S	Belongs to the peptidase M16 family	mlpA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH3_k127_3798107_6	657309.BXY_26670	1.13e-21	108.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,2FQ0S@200643|Bacteroidia,4AP64@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_3798107_4	237368.SCABRO_01345	2.64e-35	149.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	-	-	2.4.1.21	ko:K00703,ko:K00754	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT4,GT5	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH3_k127_3798107_3	1116472.MGMO_162c00020	1.166e-39	162.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria,1XFN6@135618|Methylococcales	135618|Methylococcales	M	Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_3798107_0	644282.Deba_2080	3.131e-143	468.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YHH3_k127_3798107_2	1128421.JAGA01000002_gene1829	9.047e-66	232.0	COG1215@1|root,COG1215@2|Bacteria,2NPW4@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_3798107_1	323848.Nmul_A0277	1.694e-66	240.0	COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,1MV8J@1224|Proteobacteria,2W9NC@28216|Betaproteobacteria,3726J@32003|Nitrosomonadales	28216|Betaproteobacteria	M	GtrA-like protein	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
YHH3_k127_3798107_5	234621.RER_24940	3.443e-22	107.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4G5BP@85025|Nocardiaceae	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
YHH3_k127_3804239_2	500632.CLONEX_03374	6.669e-19	91.0	COG0745@1|root,COG0745@2|Bacteria,1U4FM@1239|Firmicutes,24DF2@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	ko:K18344	ko01502,ko02020,map01502,map02020	M00651,M00656	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH3_k127_3804239_0	521045.Kole_0110	7.103e-41	166.0	COG0642@1|root,COG2205@2|Bacteria	521045.Kole_0110|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_3804239_1	1121324.CLIT_23c00860	1.602e-35	146.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia	186801|Clostridia	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	hofD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
YHH3_k127_3804239_4	1268237.G114_05840	0.0007057	48.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1Y4SI@135624|Aeromonadales	135624|Aeromonadales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
YHH3_k127_3804239_3	944481.JAFP01000001_gene562	5.303e-09	58.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2M6F4@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH3_k127_3845384_3	1304880.JAGB01000001_gene957	4.097e-05	53.0	COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,24MYD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
YHH3_k127_3845384_0	1166018.FAES_5285	3.338e-56	212.0	COG0389@1|root,COG0389@2|Bacteria,4NKZ5@976|Bacteroidetes,47TAN@768503|Cytophagia	976|Bacteroidetes	L	impB/mucB/samB family C-terminal domain	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
YHH3_k127_3845384_1	161156.JQKW01000006_gene1055	2.014e-44	169.0	COG0024@1|root,COG0024@2|Bacteria,2GH34@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YHH3_k127_3845384_2	765952.PUV_18560	1.591e-05	47.0	COG0024@1|root,COG0024@2|Bacteria,2JFE5@204428|Chlamydiae	204428|Chlamydiae	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
YHH3_k127_3878162_0	926569.ANT_23480	3.633e-234	741.0	COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
YHH3_k127_3878162_2	673860.AciM339_1486	3.958e-156	519.0	COG0209@1|root,arCOG03713@1|root,arCOG03713@2157|Archaea,arCOG04276@2157|Archaea,2XUBW@28890|Euryarchaeota,3F2JF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
YHH3_k127_3878162_4	930945.SiRe_1623	9.851e-34	138.0	COG2096@1|root,arCOG00489@2157|Archaea,2XQXF@28889|Crenarchaeota	28889|Crenarchaeota	H	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
YHH3_k127_3878162_1	665571.STHERM_c15920	1.35e-220	716.0	COG0060@1|root,COG0060@2|Bacteria,2J57V@203691|Spirochaetes	203691|Spirochaetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YHH3_k127_3878162_3	555779.Dthio_PD0936	1.464e-66	240.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2M7YK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
YHH3_k127_3878162_6	158189.SpiBuddy_0982	9.275e-24	103.0	COG1162@1|root,COG1162@2|Bacteria,2JAVX@203691|Spirochaetes	203691|Spirochaetes	S	RNHCP domain	-	-	-	-	-	-	-	-	-	-	-	-	RNHCP
YHH3_k127_3878162_9	568816.Acin_2147	1.477e-13	76.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4H4VN@909932|Negativicutes	909932|Negativicutes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
YHH3_k127_3878162_7	706587.Desti_0403	1.156e-21	96.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2MQKU@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YHH3_k127_3878162_5	1122927.KB895412_gene1293	3.452e-25	111.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,26TZY@186822|Paenibacillaceae	91061|Bacilli	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
YHH3_k127_3878162_10	877455.Metbo_1639	1.453e-09	69.0	COG0330@1|root,arCOG01915@2157|Archaea,2XTA2@28890|Euryarchaeota	28890|Euryarchaeota	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH3_k127_3878162_8	1321784.HMPREF1987_02197	1.459e-18	99.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
YHH3_k127_3891813_1	497964.CfE428DRAFT_0045	2.655e-09	60.0	COG0143@1|root,COG0143@2|Bacteria,46SCQ@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
YHH3_k127_3891813_0	1047013.AQSP01000140_gene2513	3.397e-42	168.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
YHH3_k127_4163889_0	439235.Dalk_0845	3.997e-68	238.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria,2MKSR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
YHH3_k127_4163889_1	42256.RradSPS_0178	6.903e-21	108.0	COG3463@1|root,COG3463@2|Bacteria,2GKJJ@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
YHH3_k127_4163889_2	457396.CSBG_00481	3.771e-07	63.0	COG2244@1|root,COG2244@2|Bacteria,1TPSH@1239|Firmicutes,2492X@186801|Clostridia,36FXH@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
YHH3_k127_4164542_3	768710.DesyoDRAFT_0438	8.89e-10	63.0	COG0762@1|root,COG0762@2|Bacteria,1VN1M@1239|Firmicutes,24X1E@186801|Clostridia,265M7@186807|Peptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
YHH3_k127_4164542_2	574966.KB898650_gene394	7.658e-19	98.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RZ1Y@1236|Gammaproteobacteria,1XRCH@135619|Oceanospirillales	135619|Oceanospirillales	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
YHH3_k127_4164542_1	167539.Pro_1264	2.216e-30	128.0	COG1285@1|root,COG1285@2|Bacteria	2|Bacteria	E	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
YHH3_k127_4164542_0	203119.Cthe_0239	5.305e-67	248.0	COG5337@1|root,COG5337@2|Bacteria,1TRAW@1239|Firmicutes,24AQY@186801|Clostridia,3WI9B@541000|Ruminococcaceae	186801|Clostridia	M	Fn3 associated	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Dockerin_1,Fn3_assoc,LTD
YHH3_k127_4164542_4	1121344.JHZO01000004_gene1358	0.0002615	48.0	COG5036@1|root,COG5036@2|Bacteria,1V78G@1239|Firmicutes,25D4S@186801|Clostridia	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
YHH3_k127_4207337_0	1403313.AXBR01000006_gene73	7.456e-71	254.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
YHH3_k127_4207337_4	1123325.JHUV01000008_gene891	6.841e-10	62.0	COG0238@1|root,COG0238@2|Bacteria,2G49C@200783|Aquificae	200783|Aquificae	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
YHH3_k127_4207337_2	1167006.UWK_02825	2.019e-34	138.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2MKNW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YHH3_k127_4207337_3	309799.DICTH_1249	1.209e-14	77.0	COG0360@1|root,COG0360@2|Bacteria	2|Bacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
YHH3_k127_4207337_1	1347392.CCEZ01000043_gene181	9.467e-67	234.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,36E7J@31979|Clostridiaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YHH3_k127_4307101_2	158190.SpiGrapes_0110	4.625e-39	148.0	COG0215@1|root,COG0215@2|Bacteria,2J618@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
YHH3_k127_4307101_1	1141106.CAIB01000054_gene409	2.721e-59	211.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,4GXXK@90964|Staphylococcaceae	91061|Bacilli	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
YHH3_k127_4307101_0	1293054.HSACCH_01735	2.111e-82	294.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WAIF@53433|Halanaerobiales	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
YHH3_k127_4307101_3	697282.Mettu_1349	3.47e-38	149.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1XF29@135618|Methylococcales	135618|Methylococcales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
YHH3_k127_4307101_4	547144.HydHO_1397	3.328e-18	88.0	COG0319@1|root,COG0319@2|Bacteria	2|Bacteria	C	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.6.99.2,3.5.4.5	ko:K01489,ko:K03474,ko:K03595,ko:K07042	ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100	M00124	R01878,R02485,R05838,R08221	RC00074,RC00514,RC01476	ko00000,ko00001,ko00002,ko01000,ko03009,ko03029	-	-	-	UPF0054
YHH3_k127_4307101_6	909663.KI867150_gene1999	6.845e-08	58.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,42SH8@68525|delta/epsilon subdivisions,2WQ3S@28221|Deltaproteobacteria,2MQNY@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
YHH3_k127_4307101_7	161156.JQKW01000007_gene620	1.045e-05	51.0	COG0828@1|root,COG0828@2|Bacteria,2GI0S@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
YHH3_k127_4307101_5	665956.HMPREF1032_01082	1.18e-13	73.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WGQW@541000|Ruminococcaceae	186801|Clostridia	M	Metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
YHH3_k127_4322312_7	37659.JNLN01000001_gene743	1.246e-07	53.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,36DC4@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
YHH3_k127_4322312_3	264732.Moth_0834	1.804e-26	113.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,42GA2@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
YHH3_k127_4322312_1	644966.Tmar_0862	9.837e-68	241.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3WCDX@538999|Clostridiales incertae sedis	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
YHH3_k127_4322312_0	525904.Tter_1614	1.358e-108	373.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PASTA,PBP_dimer,Transpeptidase
YHH3_k127_4322312_4	1121422.AUMW01000002_gene2156	5.749e-23	102.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,262GM@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
YHH3_k127_4322312_6	771875.Ferpe_2047	5.106e-19	98.0	COG1316@1|root,COG1316@2|Bacteria,2GCZH@200918|Thermotogae	200918|Thermotogae	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
YHH3_k127_4322312_5	706587.Desti_5065	2.361e-20	95.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YHH3_k127_4322312_2	1499967.BAYZ01000184_gene4610	4.639e-43	169.0	COG0642@1|root,COG2205@2|Bacteria,2NQZ3@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YHH3_k127_4326380_2	1123376.AUIU01000014_gene701	6.199e-22	99.0	COG0758@1|root,COG0758@2|Bacteria,3J0Q8@40117|Nitrospirae	40117|Nitrospirae	L	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
YHH3_k127_4326380_1	1304284.L21TH_0447	1.381e-31	130.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,36I5W@31979|Clostridiaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
YHH3_k127_4326380_0	765420.OSCT_3154	4.367e-35	138.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi,375VM@32061|Chloroflexia	32061|Chloroflexia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
YHH3_k127_4326380_3	247490.KSU1_C1041	5.984e-20	95.0	COG1085@1|root,COG1085@2|Bacteria,2IX2C@203682|Planctomycetes	203682|Planctomycetes	C	galactose-1-phosphate uridylyltransferase	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
YHH3_k127_4368885_0	1237149.C900_02118	6.811e-119	388.0	COG1266@1|root,COG1266@2|Bacteria,4NVAP@976|Bacteroidetes,47SVF@768503|Cytophagia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
YHH3_k127_4368885_1	1236689.MMALV_10810	3.555e-13	75.0	arCOG03272@1|root,arCOG03272@2157|Archaea,2Y1VM@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	2.7.7.6	ko:K00960	-	-	-	-	ko00000,ko01000	-	-	-	-
YHH3_k127_4415116_1	1125699.HMPREF9194_00427	5.077e-10	68.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2J6RF@203691|Spirochaetes	203691|Spirochaetes	M	LysM domain M23 M37 peptidase domain protein	nlpD	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
YHH3_k127_4415116_0	1128421.JAGA01000003_gene3494	2.743e-130	422.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
YHH3_k127_4509731_4	357808.RoseRS_1978	2.538e-24	113.0	COG1922@1|root,COG1922@2|Bacteria,2G6J0@200795|Chloroflexi,375GH@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyl transferase, WecB TagA CpsF family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
YHH3_k127_4509731_0	768670.Calni_0362	4.343e-113	374.0	COG1077@1|root,COG1077@2|Bacteria,2GEVU@200930|Deferribacteres	200930|Deferribacteres	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH3_k127_4509731_6	694440.JOMF01000007_gene874	6.992e-06	58.0	arCOG03264@1|root,arCOG03264@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
YHH3_k127_4509731_8	457570.Nther_2116	0.000184	51.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
YHH3_k127_4509731_9	622637.KE124774_gene2573	0.0003852	45.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,36XJI@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YHH3_k127_4509731_2	572478.Vdis_2035	1.072e-48	180.0	COG0105@1|root,arCOG04313@2157|Archaea,2XQEV@28889|Crenarchaeota	28889|Crenarchaeota	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YHH3_k127_4509731_7	1121859.KB890739_gene2278	0.0001711	53.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,47N9T@768503|Cytophagia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ_2,PQQ_3
YHH3_k127_4509731_1	227086.JGI_V11_50244	2.555e-60	231.0	COG0018@1|root,KOG1195@2759|Eukaryota	2759|Eukaryota	J	arginyl-tRNA aminoacylation	RARS2	GO:0000959,GO:0002181,GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031974,GO:0032543,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070127,GO:0070144,GO:0071704,GO:0090304,GO:0140053,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	3.6.3.8,6.1.1.19	ko:K01537,ko:K01887,ko:K02890	ko00970,ko03010,map00970,map03010	M00178,M00179,M00359,M00360	R03646	RC00055,RC00523	br01610,ko00000,ko00001,ko00002,ko01000,ko01007,ko03011,ko03016,ko03029	3.A.3.2	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YHH3_k127_4509731_3	293826.Amet_3062	5.095e-38	153.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,36DFY@31979|Clostridiaceae	186801|Clostridia	L	domain protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Lactamase_B
YHH3_k127_4509731_5	357808.RoseRS_1609	3.036e-23	109.0	COG0658@1|root,COG0658@2|Bacteria,2G6G7@200795|Chloroflexi,375B1@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ComEC Rec2-related protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
YHH3_k127_4515018_1	1304872.JAGC01000003_gene2877	2.932e-39	148.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2M8MT@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YHH3_k127_4515018_2	1347369.CCAD010000024_gene1506	4.56e-07	63.0	COG2374@1|root,COG3225@1|root,COG4677@1|root,COG2374@2|Bacteria,COG3225@2|Bacteria,COG4677@2|Bacteria,1UJUI@1239|Firmicutes,4I2BS@91061|Bacilli,1ZCHV@1386|Bacillus	91061|Bacilli	N	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,LTD
YHH3_k127_4515018_0	309799.DICTH_1585	7.839e-101	339.0	COG0215@1|root,COG0215@2|Bacteria	2|Bacteria	J	cysteine-tRNA ligase activity	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
YHH3_k127_4575652_0	1347393.HG726020_gene939	3.751e-128	413.0	COG3752@1|root,COG3752@2|Bacteria,4NJXA@976|Bacteroidetes,2FWRU@200643|Bacteroidia	976|Bacteroidetes	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
YHH3_k127_4575652_1	1347393.HG726020_gene940	1.665e-83	280.0	COG1307@1|root,COG1461@1|root,COG1307@2|Bacteria,COG1461@2|Bacteria,4NXDG@976|Bacteroidetes,2FUZ2@200643|Bacteroidia	976|Bacteroidetes	S	Dihydroxyacetone kinase family	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
YHH3_k127_4662289_4	697303.Thewi_1346	7.594e-07	58.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,42EMT@68295|Thermoanaerobacterales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
YHH3_k127_4662289_2	195103.CPF_1950	8.902e-47	178.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,36DDR@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
YHH3_k127_4662289_3	1094508.Tsac_0634	1.943e-29	130.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,42FIY@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ROK family protein	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
YHH3_k127_4662289_1	998674.ATTE01000001_gene3400	1.451e-58	216.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,1RQQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
YHH3_k127_4662289_0	82654.Pse7367_1026	9.135e-83	287.0	COG0343@1|root,COG0343@2|Bacteria,1G0EV@1117|Cyanobacteria,1H81I@1150|Oscillatoriales	2|Bacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	-	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
YHH3_k127_4704896_3	1196031.ALEG01000039_gene1345	3.78e-14	81.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bpr	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8
YHH3_k127_4704896_4	861299.J421_3486	6.833e-11	74.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	PglL_A,Wzy_C,Wzy_C_2
YHH3_k127_4704896_1	868131.MSWAN_1336	2.634e-31	138.0	COG2244@1|root,arCOG02209@2157|Archaea,2XSUR@28890|Euryarchaeota	28890|Euryarchaeota	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
YHH3_k127_4704896_0	153721.MYP_3548	1.383e-39	163.0	COG3858@1|root,COG3858@2|Bacteria,4NJZ6@976|Bacteroidetes,47QYP@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Glyco_hydro_18,Laminin_G_3
YHH3_k127_4786551_3	273068.TTE1768	1.677e-09	64.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,42EY6@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM VanW family protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
YHH3_k127_4786551_0	1047013.AQSP01000107_gene2079	9.331e-61	214.0	COG1432@1|root,COG1432@2|Bacteria,2NRX6@2323|unclassified Bacteria	2|Bacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
YHH3_k127_4786551_1	575590.HMPREF0156_01408	1.1e-56	206.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YHH3_k127_4786551_2	269797.Mbar_A0935	1.135e-18	92.0	COG0269@1|root,arCOG00103@2157|Archaea,2XUYW@28890|Euryarchaeota,2N9CN@224756|Methanomicrobia	224756|Methanomicrobia	F	Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin	fae-hps	-	4.1.2.43,4.2.1.147	ko:K13812	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338,R08058	RC00421,RC00422,RC01583,RC01795	ko00000,ko00001,ko00002,ko01000	-	-	-	Fae,OMPdecase
YHH3_k127_4826730_6	1235799.C818_03980	1.268e-06	55.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,27I7N@186928|unclassified Lachnospiraceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
YHH3_k127_4826730_0	195103.CPF_0296	2.719e-73	253.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,36DHJ@31979|Clostridiaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
YHH3_k127_4826730_7	679937.Bcop_0033	1.957e-06	55.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,2FTKZ@200643|Bacteroidia,4ANHR@815|Bacteroidaceae	976|Bacteroidetes	S	Conserved protein	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
YHH3_k127_4826730_3	1033737.CAEV01000017_gene3113	4.223e-40	162.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,36FDF@31979|Clostridiaceae	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
YHH3_k127_4826730_4	1280689.AUJC01000004_gene347	2.724e-23	111.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,36EAC@31979|Clostridiaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YHH3_k127_4826730_1	1195236.CTER_0665	7.674e-49	186.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YHH3_k127_4826730_2	1382306.JNIM01000001_gene1978	3.426e-40	165.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH3_k127_4826730_5	1111479.AXAR01000016_gene3077	4.96e-22	98.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,27851@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YHH3_k127_4873776_0	1304880.JAGB01000002_gene2423	1.566e-36	146.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
YHH3_k127_5054904_0	573370.DMR_19300	1.848e-06	59.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YHH3_k127_5094586_4	869213.JCM21142_124700	1.709e-20	92.0	COG1106@1|root,COG1106@2|Bacteria,4NE5J@976|Bacteroidetes,47NIN@768503|Cytophagia	976|Bacteroidetes	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
YHH3_k127_5094586_5	1121887.AUDK01000002_gene1979	1.16e-15	79.0	COG1669@1|root,COG1669@2|Bacteria,4NW39@976|Bacteroidetes,1II94@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
YHH3_k127_5094586_2	1239962.C943_03065	1.207e-34	137.0	COG2963@1|root,COG2963@2|Bacteria,4NQ8V@976|Bacteroidetes	976|Bacteroidetes	L	Pfam Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
YHH3_k127_5094586_0	1239962.C943_03064	2.193e-95	321.0	COG2801@1|root,COG2801@2|Bacteria,4NRIR@976|Bacteroidetes,47XPK@768503|Cytophagia	976|Bacteroidetes	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
YHH3_k127_5094586_1	760192.Halhy_3354	3.741e-46	171.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_3,YkuD
YHH3_k127_5094586_3	1121904.ARBP01000045_gene1842	1.31e-31	127.0	COG0457@1|root,COG0642@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47TVA@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,TPR_8,Y_Y_Y
YHH3_k127_5241378_0	1120973.AQXL01000112_gene1070	4.174e-189	602.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,2783X@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YHH3_k127_5241378_3	684719.HIMB114_00003960	6.897e-41	155.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2TSI8@28211|Alphaproteobacteria,4BQ5M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YHH3_k127_5241378_2	272635.MYPU_4300	1.408e-49	181.0	COG0048@1|root,COG0048@2|Bacteria,3WTGE@544448|Tenericutes	544448|Tenericutes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
YHH3_k127_5241378_1	1121324.CLIT_24c00740	4.339e-102	343.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,25QQ9@186804|Peptostreptococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH3_k127_5648110_8	1487953.JMKF01000066_gene3778	2.409e-28	120.0	COG0691@1|root,COG0691@2|Bacteria,1G542@1117|Cyanobacteria,1HAV9@1150|Oscillatoriales	1117|Cyanobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YHH3_k127_5648110_12	394503.Ccel_0527	1.504e-05	58.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,36DFG@31979|Clostridiaceae	186801|Clostridia	D	TIGRFAM SpoIID LytB domain	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	PG_binding_1,SpoIID,Y_Y_Y
YHH3_k127_5648110_14	1449048.JQKU01000001_gene1975	0.0006926	49.0	COG5412@1|root,COG5412@2|Bacteria,2GNNQ@201174|Actinobacteria,23809@1762|Mycobacteriaceae	201174|Actinobacteria	M	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail,SLT
YHH3_k127_5648110_13	926550.CLDAP_14730	0.0002789	50.0	COG0664@1|root,COG3428@1|root,COG0664@2|Bacteria,COG3428@2|Bacteria,2G72V@200795|Chloroflexi	200795|Chloroflexi	K	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
YHH3_k127_5648110_7	1284708.HMPREF1634_01875	9.314e-31	130.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,3WCPU@538999|Clostridiales incertae sedis	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
YHH3_k127_5648110_0	1123371.ATXH01000005_gene2143	4.921e-175	575.0	COG0525@1|root,COG0525@2|Bacteria,2GGVS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
YHH3_k127_5648110_3	632518.Calow_0436	6.953e-72	253.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,42FHT@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
YHH3_k127_5648110_5	443144.GM21_1334	5.963e-63	225.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
YHH3_k127_5648110_2	1121468.AUBR01000047_gene1877	1.804e-83	288.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,42EXJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YHH3_k127_5648110_9	882086.SacxiDRAFT_0788	3.425e-20	104.0	COG2182@1|root,COG2182@2|Bacteria,2I2J8@201174|Actinobacteria,4E15M@85010|Pseudonocardiales	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_1,SBP_bac_8
YHH3_k127_5648110_11	331113.SNE_A02330	5.393e-11	74.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
YHH3_k127_5648110_6	1089553.Tph_c22240	9.576e-63	225.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,42FTD@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM CobB CobQ domain protein glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
YHH3_k127_5648110_4	102232.GLO73106DRAFT_00019880	6.343e-68	245.0	COG0769@1|root,COG0769@2|Bacteria,1G226@1117|Cyanobacteria	1117|Cyanobacteria	M	Mur ligase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
YHH3_k127_5648110_1	865861.AZSU01000006_gene1168	5.682e-117	391.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,36DSQ@31979|Clostridiaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
YHH3_k127_5648110_10	269797.Mbar_A0192	5.149e-17	90.0	COG0637@1|root,arCOG02293@2157|Archaea,2XTYU@28890|Euryarchaeota,2NARY@224756|Methanomicrobia	224756|Methanomicrobia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YHH3_k127_5674840_3	500633.CLOHIR_01218	1.526e-82	289.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,25QTZ@186804|Peptostreptococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
YHH3_k127_5674840_5	1120973.AQXL01000075_gene964	2.197e-60	220.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,2792X@186823|Alicyclobacillaceae	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH3_k127_5674840_6	1444310.JANV01000025_gene3828	1.551e-26	110.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,1ZHUS@1386|Bacillus	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YHH3_k127_5674840_4	436114.SYO3AOP1_0797	2.564e-64	228.0	COG1692@1|root,COG1692@2|Bacteria,2G3Y9@200783|Aquificae	200783|Aquificae	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
YHH3_k127_5674840_2	1157490.EL26_05420	3.065e-116	392.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,277VR@186823|Alicyclobacillaceae	91061|Bacilli	S	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
YHH3_k127_5674840_7	1285586.H131_01345	1.651e-05	53.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,3IWD7@400634|Lysinibacillus	91061|Bacilli	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
YHH3_k127_5674840_0	316274.Haur_4194	1.959e-142	460.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi,3756R@32061|Chloroflexia	32061|Chloroflexia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
YHH3_k127_5674840_1	945713.IALB_1767	6.58e-124	413.0	COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria	2|Bacteria	J	tRNA binding	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YHH3_k127_6001838_0	118166.JH976537_gene4824	0.0002586	53.0	COG5650@1|root,COG5650@2|Bacteria,1G8N1@1117|Cyanobacteria,1HE3U@1150|Oscillatoriales	1117|Cyanobacteria	S	phosphatidylinositol metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	ALG3
YHH3_k127_6037391_1	289376.THEYE_A1930	8.964e-21	94.0	COG0484@1|root,COG0484@2|Bacteria,3J0A7@40117|Nitrospirae	40117|Nitrospirae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YHH3_k127_6037391_0	646529.Desaci_4277	8.763e-50	192.0	COG0438@1|root,COG0438@2|Bacteria,1V2Z3@1239|Firmicutes,24BN2@186801|Clostridia,2627Y@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_6037391_2	1120959.ATXF01000004_gene2850	2.621e-13	74.0	COG0438@1|root,COG0438@2|Bacteria,2GN9W@201174|Actinobacteria,4FKJJ@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YHH3_k127_6155340_1	935948.KE386495_gene1520	2.749e-234	744.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,42ETP@68295|Thermoanaerobacterales	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YHH3_k127_6155340_0	110319.CF8_0546	4.209e-252	805.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4DP2S@85009|Propionibacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YHH3_k127_6392634_0	290397.Adeh_0641	9.406e-35	146.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
YHH3_k127_6392634_1	574087.Acear_1765	0.0009203	49.0	COG4967@1|root,COG4967@2|Bacteria	2|Bacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02458,ko:K02671	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	N_methyl
YHH3_k127_6486036_9	765420.OSCT_2888	0.0003436	51.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi,37651@32061|Chloroflexia	32061|Chloroflexia	S	Alpha-2-macroglobulin family	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5
YHH3_k127_6486036_1	1172190.M947_11250	1.012e-58	211.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42TAC@68525|delta/epsilon subdivisions,2YRI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG2518 Protein-L-isoaspartate carboxylmethyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
YHH3_k127_6486036_0	1497679.EP56_12930	6.057e-74	257.0	COG3752@1|root,COG3752@2|Bacteria,1V0FI@1239|Firmicutes,4HDGV@91061|Bacilli,26N3U@186820|Listeriaceae	91061|Bacilli	S	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
YHH3_k127_6486036_5	1069080.KB913028_gene832	6.179e-42	161.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4H437@909932|Negativicutes	909932|Negativicutes	S	Peptidase M50	spoIVFB	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
YHH3_k127_6486036_7	556269.ACDQ01000018_gene939	7.47e-05	47.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,2VUEX@28216|Betaproteobacteria,474JH@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
YHH3_k127_6486036_3	316274.Haur_0121	1.355e-55	205.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi,37569@32061|Chloroflexia	32061|Chloroflexia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
YHH3_k127_6486036_4	1304888.ATWF01000001_gene1550	3.818e-51	185.0	COG0080@1|root,COG0080@2|Bacteria,2GFIM@200930|Deferribacteres	200930|Deferribacteres	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
YHH3_k127_6486036_6	1123405.AUMM01000026_gene2174	8.24e-41	158.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,26NER@186821|Sporolactobacillaceae	91061|Bacilli	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
YHH3_k127_6486036_8	1538295.JY96_08945	7.875e-05	48.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,1KKT3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
YHH3_k127_6486036_2	573061.Clocel_3049	2.22e-58	209.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,36ERS@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
YHH3_k127_6524250_1	1121472.AQWN01000005_gene2471	9.523e-37	147.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,261GI@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH3_k127_6524250_0	879212.DespoDRAFT_01856	9.098e-123	407.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,42N2K@68525|delta/epsilon subdivisions,2WJ5D@28221|Deltaproteobacteria,2MI1X@213118|Desulfobacterales	28221|Deltaproteobacteria	S	FAD binding domain	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	DAO,FAD_binding_2,GIDA,HI0933_like,Pyr_redox_2
YHH3_k127_6686479_0	865861.AZSU01000007_gene1080	5.208e-162	528.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,36DIC@31979|Clostridiaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YHH3_k127_6686479_1	311424.DhcVS_1172	9.544e-66	235.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,34CQM@301297|Dehalococcoidia	301297|Dehalococcoidia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
YHH3_k127_6686479_2	289376.THEYE_A0693	1.028e-55	203.0	COG0177@1|root,COG0177@2|Bacteria,3J0K6@40117|Nitrospirae	40117|Nitrospirae	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YHH3_k127_6686479_4	882082.SaccyDRAFT_2655	1.392e-28	128.0	COG1651@1|root,COG1651@2|Bacteria,2GM6C@201174|Actinobacteria,4E3T8@85010|Pseudonocardiales	201174|Actinobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YHH3_k127_6686479_5	1293054.HSACCH_00622	2.589e-23	111.0	COG0524@1|root,COG0524@2|Bacteria,1UYF8@1239|Firmicutes,24IJ1@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YHH3_k127_6686479_3	580340.Tlie_1477	2.587e-46	171.0	COG3958@1|root,COG3958@2|Bacteria,3TAN6@508458|Synergistetes	508458|Synergistetes	G	PFAM Transketolase, C-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
YHH3_k127_6791089_3	102232.GLO73106DRAFT_00019690	8.24e-32	126.0	COG0187@1|root,COG0187@2|Bacteria,1G139@1117|Cyanobacteria	1117|Cyanobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,HTH_3,Intein_splicing,LAGLIDADG_3,Toprim
YHH3_k127_6791089_4	340099.Teth39_2147	6.725e-17	89.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,42FRN@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
YHH3_k127_6791089_0	1423321.AS29_04510	2.577e-138	459.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZD5J@1386|Bacillus	91061|Bacilli	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH3_k127_6791089_1	1192034.CAP_4063	4.908e-90	308.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2YWXD@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YHH3_k127_6791089_2	379066.GAU_2568	1.843e-66	239.0	COG1459@1|root,COG1459@2|Bacteria,1ZT63@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YHH3_k127_6872227_1	1541065.JRFE01000019_gene3238	6.231e-05	54.0	COG0689@1|root,COG0823@1|root,COG2133@1|root,COG2304@1|root,COG2931@1|root,COG0689@2|Bacteria,COG0823@2|Bacteria,COG2133@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,1GJ0J@1117|Cyanobacteria,3VIZ2@52604|Pleurocapsales	1117|Cyanobacteria	QU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,SdrD_B
YHH3_k127_6904126_2	1122176.KB903553_gene3675	2.853e-21	95.0	COG0673@1|root,COG0673@2|Bacteria,4NFGY@976|Bacteroidetes,1IR4M@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YHH3_k127_6904126_0	1341181.FLJC2902T_28550	1.077e-24	114.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_6904126_1	1408433.JHXV01000006_gene2730	3.519e-22	96.0	COG3708@1|root,COG3708@2|Bacteria,4NQ46@976|Bacteroidetes,1I45F@117743|Flavobacteriia	976|Bacteroidetes	K	transcription activator, effector binding	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like
YHH3_k127_7041398_1	638303.Thal_0680	1.147e-33	136.0	COG0290@1|root,COG0290@2|Bacteria,2G432@200783|Aquificae	200783|Aquificae	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
YHH3_k127_7041398_0	373903.Hore_05580	6.125e-177	571.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WAG8@53433|Halanaerobiales	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
YHH3_k127_7058787_2	1298880.AUEV01000001_gene5870	2.539e-20	93.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria	201174|Actinobacteria	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
YHH3_k127_7058787_1	1414720.CBYM010000001_gene851	3.601e-25	119.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,36DH6@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the peptidase M16 family	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YHH3_k127_7058787_3	383372.Rcas_1150	2.534e-15	89.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_7058787_0	204669.Acid345_3127	1.542e-52	195.0	COG0500@1|root,COG2226@2|Bacteria,3Y8WR@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH3_k127_706166_0	1304872.JAGC01000003_gene2602	8.53e-168	544.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42QFH@68525|delta/epsilon subdivisions,2WKWR@28221|Deltaproteobacteria,2MAT5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YHH3_k127_706166_1	1280685.AUKC01000003_gene2924	1.003e-78	274.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
YHH3_k127_706166_2	565033.GACE_0493	1.342e-54	201.0	COG0463@1|root,arCOG00895@2157|Archaea,2Y7SU@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_706166_7	1249975.JQLP01000001_gene3443	6.626e-12	78.0	COG2244@1|root,COG2244@2|Bacteria,4NG0R@976|Bacteroidetes,1HXJY@117743|Flavobacteriia	976|Bacteroidetes	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
YHH3_k127_706166_3	357808.RoseRS_0394	2.063e-39	166.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_706166_5	745310.G432_10875	9.854e-23	113.0	COG1287@1|root,COG1287@2|Bacteria,1R184@1224|Proteobacteria,2TYYC@28211|Alphaproteobacteria,2KEPT@204457|Sphingomonadales	204457|Sphingomonadales	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_706166_6	926550.CLDAP_32470	6.307e-18	98.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_706166_4	1499967.BAYZ01000090_gene4950	2.527e-28	125.0	COG0392@1|root,COG0392@2|Bacteria,2NPJC@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YHH3_k127_7075731_0	304371.MCP_0607	6.48e-07	58.0	COG0575@1|root,arCOG04106@2157|Archaea,2XWNR@28890|Euryarchaeota,2N9PZ@224756|Methanomicrobia	224756|Methanomicrobia	I	Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids	carS	-	2.7.7.67	ko:K19664	ko00564,map00564	-	R08966	RC00002	ko00000,ko00001,ko01000	-	-	-	CarS-like
YHH3_k127_7075731_1	886293.Sinac_2627	3.683e-05	53.0	COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria,2J236@203682|Planctomycetes	203682|Planctomycetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7372596_1	273068.TTE2546	2.481e-47	185.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,42EWR@68295|Thermoanaerobacterales	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YHH3_k127_7372596_4	907348.TresaDRAFT_2064	4.951e-10	71.0	COG3391@1|root,COG3391@2|Bacteria,2J5ZD@203691|Spirochaetes	203691|Spirochaetes	S	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
YHH3_k127_7372596_2	574087.Acear_0743	2.219e-44	174.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3WA7V@53433|Halanaerobiales	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
YHH3_k127_7372596_3	768710.DesyoDRAFT_1785	3.381e-32	133.0	COG1595@1|root,COG1595@2|Bacteria,1V4E2@1239|Firmicutes,24GZP@186801|Clostridia,262C3@186807|Peptococcaceae	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YHH3_k127_7372596_0	525904.Tter_0997	1.008e-70	251.0	COG0391@1|root,COG0391@2|Bacteria,2NP7Q@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0052	ybhK	-	-	-	-	-	-	-	-	-	-	-	UPF0052
YHH3_k127_7372596_6	1150399.AQYK01000002_gene3016	0.0008665	48.0	COG2165@1|root,COG2165@2|Bacteria,2GTN8@201174|Actinobacteria,4FQ6P@85023|Microbacteriaceae	201174|Actinobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
YHH3_k127_7372596_5	755732.Fluta_2922	7.791e-10	61.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1HXC3@117743|Flavobacteriia,2PAKG@246874|Cryomorphaceae	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH3_k127_7467265_0	596151.DesfrDRAFT_2417	8.477e-106	351.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,42PZ9@68525|delta/epsilon subdivisions,2WM8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_7467265_1	304371.MCP_0779	2.209e-97	328.0	COG1817@1|root,arCOG01395@2157|Archaea,2XT3W@28890|Euryarchaeota,2NAFU@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
YHH3_k127_7467265_2	1026882.MAMP_03041	1.468e-64	229.0	COG0500@1|root,COG0500@2|Bacteria,1QV5S@1224|Proteobacteria,1SDB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YHH3_k127_7467265_4	883.DvMF_1042	6.06e-16	86.0	COG2227@1|root,COG2227@2|Bacteria,1MZ3S@1224|Proteobacteria,42ZIR@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
YHH3_k127_7467265_3	797209.ZOD2009_15486	7.735e-45	171.0	COG0297@1|root,arCOG01420@2157|Archaea,2Y8BY@28890|Euryarchaeota,23UH1@183963|Halobacteria	183963|Halobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_7542214_0	243275.TDE_2472	4.907e-75	268.0	COG2801@1|root,COG2801@2|Bacteria,2JAQ6@203691|Spirochaetes	203691|Spirochaetes	L	similarity to SP Q54513	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
YHH3_k127_7629549_1	1121382.JQKG01000082_gene698	8.766e-15	85.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_C39_2
YHH3_k127_7629549_0	1122223.KB890700_gene2114	1.598e-82	286.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	COesterase,DUF2920,Peptidase_S9
YHH3_k127_7720918_1	1051632.TPY_3253	1.664e-13	83.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_7720918_0	525904.Tter_1842	9.583e-59	210.0	COG2148@1|root,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
YHH3_k127_7749164_0	1128421.JAGA01000002_gene123	7.616e-115	387.0	COG0297@1|root,COG0297@2|Bacteria,2NP1F@2323|unclassified Bacteria	2|Bacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	iLJ478.TM0895	Glyco_transf_5,Glycos_transf_1
YHH3_k127_7749164_4	178306.PAE1048	2.341e-06	60.0	COG1449@1|root,arCOG03279@2157|Archaea,2XRP2@28889|Crenarchaeota	28889|Crenarchaeota	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
YHH3_k127_7749164_3	633148.Tagg_0642	5.342e-07	62.0	COG1449@1|root,arCOG03280@2157|Archaea,2XQ3V@28889|Crenarchaeota	28889|Crenarchaeota	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
YHH3_k127_7749164_1	521045.Kole_1922	2.382e-93	323.0	COG0297@1|root,COG0297@2|Bacteria,2GC9U@200918|Thermotogae	200918|Thermotogae	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	iLJ478.TM0895	Glyco_transf_5,Glycos_transf_1
YHH3_k127_7749164_2	1031288.AXAA01000010_gene436	2.229e-28	122.0	COG1085@1|root,COG1085@2|Bacteria,1TS3F@1239|Firmicutes,249P3@186801|Clostridia,36II0@31979|Clostridiaceae	186801|Clostridia	C	galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
YHH3_k127_7763879_3	565045.NOR51B_1100	5.564e-07	55.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
YHH3_k127_7763879_1	1211815.CBYP010000036_gene2307	4.908e-15	84.0	COG3764@1|root,COG3764@2|Bacteria,2IR30@201174|Actinobacteria,4EVPW@85013|Frankiales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
YHH3_k127_7763879_2	485918.Cpin_3116	1.545e-09	70.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,1IPPF@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YHH3_k127_7763879_0	234267.Acid_1035	5.355e-42	164.0	COG0463@1|root,COG0463@2|Bacteria,3Y982@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YHH3_k127_7814475_0	289376.THEYE_A0112	6.765e-115	381.0	COG0192@1|root,COG0192@2|Bacteria,3J0A4@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YHH3_k127_7843138_0	357809.Cphy_1804	4.332e-128	440.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,21YUA@1506553|Lachnoclostridium	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
YHH3_k127_7843138_1	411463.EUBVEN_02789	4.499e-24	104.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,25V5T@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
YHH3_k127_7888894_13	926569.ANT_23480	3.33e-52	190.0	COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
YHH3_k127_7888894_3	555088.DealDRAFT_1341	2.165e-121	401.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,42JIC@68298|Syntrophomonadaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YHH3_k127_7888894_6	373903.Hore_09120	4.557e-90	311.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,24948@186801|Clostridia,3WA9N@53433|Halanaerobiales	186801|Clostridia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
YHH3_k127_7888894_17	702459.BBPR_0558	8.68e-05	53.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4D04A@85004|Bifidobacteriales	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
YHH3_k127_7888894_10	1382356.JQMP01000003_gene2221	1.855e-54	205.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi,27YX8@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
YHH3_k127_7888894_9	1121335.Clst_2083	3.086e-64	235.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
YHH3_k127_7888894_11	1096930.L284_16845	5.308e-54	206.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,2K1H1@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
YHH3_k127_7888894_16	309801.trd_0781	3.14e-05	48.0	COG1314@1|root,COG1314@2|Bacteria,2G7D9@200795|Chloroflexi,27YMZ@189775|Thermomicrobia	189775|Thermomicrobia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
YHH3_k127_7888894_7	1304880.JAGB01000001_gene365	1.733e-68	249.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
YHH3_k127_7888894_15	880073.Calab_1356	5.73e-17	95.0	COG1305@1|root,COG1305@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	TIG,Transglut_core
YHH3_k127_7888894_0	857293.CAAU_1463	0.0	1116.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,36E0I@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YHH3_k127_7888894_4	1382356.JQMP01000003_gene1889	3.505e-119	411.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,27XN3@189775|Thermomicrobia	189775|Thermomicrobia	M	Transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
YHH3_k127_7888894_2	1304284.L21TH_1543	1.164e-242	768.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,36DSR@31979|Clostridiaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YHH3_k127_7888894_12	379066.GAU_1726	6.856e-54	196.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
YHH3_k127_7888894_8	1382356.JQMP01000004_gene130	4.244e-66	235.0	COG0586@1|root,COG0586@2|Bacteria,2GBDA@200795|Chloroflexi,27YWX@189775|Thermomicrobia	189775|Thermomicrobia	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
YHH3_k127_7888894_14	648757.Rvan_0674	5.642e-25	113.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2TSQ0@28211|Alphaproteobacteria,3N6P3@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
YHH3_k127_7888894_5	403833.Pmob_1722	3.257e-93	320.0	COG0148@1|root,COG0148@2|Bacteria,2GC8K@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
YHH3_k127_7888894_1	311424.DhcVS_494	1.283e-260	823.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G6K4@200795|Chloroflexi,34CQ2@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YHH3_k127_7930527_1	500633.CLOHIR_01167	4.359e-35	141.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,25QK6@186804|Peptostreptococcaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YHH3_k127_7930527_3	58123.JOFJ01000001_gene3027	5.173e-08	64.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4EJJN@85012|Streptosporangiales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
YHH3_k127_7930527_2	98439.AJLL01000090_gene136	1.724e-16	83.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS_4,PHY,Response_reg
YHH3_k127_7930527_0	498761.HM1_2104	8.158e-48	180.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YHH3_k127_8051249_2	1121413.JMKT01000008_gene1110	4.96e-16	78.0	COG4852@1|root,COG4852@2|Bacteria,1MZHP@1224|Proteobacteria,42TD7@68525|delta/epsilon subdivisions,2WPIH@28221|Deltaproteobacteria,2MF5C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
YHH3_k127_8051249_1	1094980.Mpsy_1903	1.358e-74	260.0	COG1287@1|root,arCOG02043@2157|Archaea	2157|Archaea	S	membrane protein, required for N-linked glycosylation	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
YHH3_k127_8051249_0	267377.MMP0484	7.038e-92	316.0	COG0475@1|root,arCOG01955@2157|Archaea,2XWIX@28890|Euryarchaeota,23RH1@183939|Methanococci	183939|Methanococci	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
YHH3_k127_8099600_7	395493.BegalDRAFT_3203	2.122e-15	82.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria,461PU@72273|Thiotrichales	72273|Thiotrichales	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
YHH3_k127_8099600_3	237368.SCABRO_02487	3.088e-74	265.0	COG3259@1|root,COG3259@2|Bacteria,2IYS2@203682|Planctomycetes	203682|Planctomycetes	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
YHH3_k127_8099600_8	164757.Mjls_2119	4.062e-09	66.0	29JD5@1|root,306AN@2|Bacteria,2I9J8@201174|Actinobacteria,235QQ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8099600_9	436308.Nmar_1024	1.718e-08	59.0	COG0484@1|root,COG1141@1|root,arCOG00349@2157|Archaea,arCOG02846@2157|Archaea,41ST0@651137|Thaumarchaeota	651137|Thaumarchaeota	CO	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,Fer4_13
YHH3_k127_8099600_2	289376.THEYE_A0983	4.327e-80	276.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
YHH3_k127_8099600_1	768670.Calni_1986	2.857e-121	409.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GENW@200930|Deferribacteres	200930|Deferribacteres	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
YHH3_k127_8099600_0	1379281.AVAG01000076_gene1580	9.771e-145	494.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2M7VR@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
YHH3_k127_8099600_5	192952.MM_0232	4.809e-33	132.0	COG3324@1|root,arCOG04946@2157|Archaea,2Y3YR@28890|Euryarchaeota,2NB03@224756|Methanomicrobia	224756|Methanomicrobia	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
YHH3_k127_8099600_6	1341679.P253_03005	7.657e-28	126.0	2E6I3@1|root,30DXB@2|Bacteria,1RFPS@1224|Proteobacteria,1T1CD@1236|Gammaproteobacteria,3NTJ5@468|Moraxellaceae	1236|Gammaproteobacteria	S	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
YHH3_k127_8099600_4	484770.UFO1_2248	4.739e-51	190.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes	909932|Negativicutes	NU	Type II IV secretion system protein	epsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YHH3_k127_8286812_7	1157490.EL26_18995	8.492e-49	186.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,278W2@186823|Alicyclobacillaceae	91061|Bacilli	S	Large family of predicted nucleotide-binding domains	yacL	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TRAM
YHH3_k127_8286812_1	1280679.ATVX01000004_gene408	3.607e-127	422.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,4BWYW@830|Butyrivibrio	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
YHH3_k127_8286812_2	525909.Afer_1903	3.742e-111	387.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CMPF@84992|Acidimicrobiia	84992|Acidimicrobiia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YHH3_k127_8286812_4	485913.Krac_11272	6.289e-87	300.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
YHH3_k127_8286812_11	1121447.JONL01000022_gene3720	3.616e-22	97.0	2EPJ6@1|root,33H5U@2|Bacteria	2|Bacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_13	1032480.MLP_17290	2.596e-17	81.0	2AU0F@1|root,31JKB@2|Bacteria,2IT83@201174|Actinobacteria	201174|Actinobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_17	1329250.WOSG25_280020	1.516e-12	68.0	2DPII@1|root,3327T@2|Bacteria,1VHT9@1239|Firmicutes,4HQ1F@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_23	1392489.JPOL01000002_gene1180	5.626e-08	54.0	29BZF@1|root,2ZYXV@2|Bacteria,4PE4X@976|Bacteroidetes,1IEKB@117743|Flavobacteriia,2XKER@283735|Leeuwenhoekiella	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_14	632245.CLP_3136	9.713e-15	76.0	2ED6K@1|root,3373A@2|Bacteria,1VI2S@1239|Firmicutes,24QZV@186801|Clostridia,36TJ8@31979|Clostridiaceae	186801|Clostridia	S	the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_29	1392488.JHZY01000004_gene1645	0.0004828	44.0	2EJFV@1|root,33D6V@2|Bacteria,4NYMX@976|Bacteroidetes,1I6TP@117743|Flavobacteriia,2XKF8@283735|Leeuwenhoekiella	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_21	72658.Bostr.14018s0001.1.p	1.093e-08	59.0	2E30T@1|root,2SA69@2759|Eukaryota,37XUE@33090|Viridiplantae,3GMF3@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_19	525264.HMPREF0305_11005	5.845e-11	66.0	2BXJK@1|root,33AIX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_16	525255.HMPREF0077_1527	8.535e-13	73.0	2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,25HQ1@186801|Clostridia	186801|Clostridia	S	COG NOG38524 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_28	498761.HM1_3125	0.0001025	46.0	2DSV3@1|root,33HII@2|Bacteria,1VQ64@1239|Firmicutes,24VWA@186801|Clostridia	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_27	593750.Metfor_1581	1.237e-05	55.0	arCOG03311@1|root,arCOG03311@2157|Archaea,2Y85S@28890|Euryarchaeota,2NAYY@224756|Methanomicrobia	224756|Methanomicrobia	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
YHH3_k127_8286812_24	1304872.JAGC01000003_gene2873	1.936e-07	63.0	COG5542@1|root,COG5542@2|Bacteria,1NHCU@1224|Proteobacteria,432QU@68525|delta/epsilon subdivisions,2WX6D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mannosyltransferase (PIG-V)	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
YHH3_k127_8286812_31	321327.CYA_0809	0.0006633	48.0	COG1194@1|root,COG1194@2|Bacteria,1G7MC@1117|Cyanobacteria,1GYRR@1129|Synechococcus	1117|Cyanobacteria	L	A G-specific DNA glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
YHH3_k127_8286812_26	566461.SSFG_05975	8.697e-06	50.0	2E4EA@1|root,3068J@2|Bacteria,2GZWZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_10	566461.SSFG_05974	2.592e-23	100.0	2DMHR@1|root,32RMI@2|Bacteria,2HC0U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_30	1122971.BAME01000208_gene6775	0.0005102	43.0	2DMHR@1|root,32RMI@2|Bacteria,4NUR9@976|Bacteroidetes,2FT84@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_20	1121267.JHZL01000002_gene1115	2.863e-10	62.0	2AK5G@1|root,31AVC@2|Bacteria,1Q693@1224|Proteobacteria,432NC@68525|delta/epsilon subdivisions,2YSJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_25	1122130.AUHN01000003_gene2144	3.934e-07	51.0	2EG09@1|root,339SB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_12	1382230.ASAP_2763	7.023e-19	90.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8286812_9	1462526.BN990_04367	1.586e-24	117.0	COG1568@1|root,COG1568@2|Bacteria,1UZNH@1239|Firmicutes,4HF17@91061|Bacilli	91061|Bacilli	S	Protein of unknown function DUF43	-	-	2.5.1.128	ko:K07057	-	-	-	-	ko00000,ko01000	-	-	-	DUF43
YHH3_k127_8286812_18	1158338.JNLJ01000005_gene1639	4.946e-11	76.0	COG0739@1|root,COG0739@2|Bacteria,2G3Y3@200783|Aquificae	200783|Aquificae	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YHH3_k127_8286812_3	1499680.CCFE01000008_gene33	2.277e-93	318.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,1ZBWQ@1386|Bacillus	91061|Bacilli	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
YHH3_k127_8286812_0	994573.T472_0206750	7.461e-160	532.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,36DDM@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
YHH3_k127_8286812_5	632518.Calow_0028	1.013e-72	259.0	COG0438@1|root,COG0438@2|Bacteria,1TQN3@1239|Firmicutes,24ARN@186801|Clostridia,42I34@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_8286812_8	1122217.KB899591_gene285	4.345e-48	183.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H274@909932|Negativicutes	909932|Negativicutes	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
YHH3_k127_8286812_6	1121346.KB899814_gene1844	1.99e-54	204.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,26QB9@186822|Paenibacillaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
YHH3_k127_8286812_15	985665.HPL003_12675	9.227e-14	81.0	COG3177@1|root,COG3177@2|Bacteria,1TV5J@1239|Firmicutes,4HD0G@91061|Bacilli,275K7@186822|Paenibacillaceae	91061|Bacilli	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YHH3_k127_8538188_1	585503.HMPREF7545_0264	4.981e-190	613.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H2D7@909932|Negativicutes	909932|Negativicutes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YHH3_k127_8538188_0	926569.ANT_03530	1.351e-245	784.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YHH3_k127_8538188_2	1321814.HMPREF9089_01266	4.601e-15	78.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,25VNF@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YHH3_k127_8541048_1	1122128.AUEE01000001_gene2115	3.025e-65	228.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,4GY2Y@90964|Staphylococcaceae	91061|Bacilli	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YHH3_k127_8541048_3	457570.Nther_1101	7.018e-15	85.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YHH3_k127_8541048_0	696369.KI912183_gene2353	2.644e-104	352.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,2605P@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
YHH3_k127_8541048_4	138119.DSY0686	0.0005039	53.0	COG4637@1|root,COG4637@2|Bacteria,1UIDM@1239|Firmicutes	1239|Firmicutes	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
YHH3_k127_8541048_2	339671.Asuc_1654	4.609e-21	104.0	COG2267@1|root,COG2267@2|Bacteria,1NJPZ@1224|Proteobacteria,1TFEK@1236|Gammaproteobacteria,1Y7V6@135625|Pasteurellales	135625|Pasteurellales	I	protein of Bacteria UniRef RepID	-	-	-	-	-	-	-	-	-	-	-	-	DUF1749,Hydrolase_4
YHH3_k127_8643252_2	1461580.CCAS010000015_gene1842	1.036e-06	51.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8643252_1	768726.HMPREF9178_0236	9.32e-40	159.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,2TP3R@28037|Streptococcus mitis	91061|Bacilli	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
YHH3_k127_8643252_3	1385511.N783_17390	1.035e-05	55.0	COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,2Y9DE@289201|Pontibacillus	91061|Bacilli	EGP	MFS transporter	yuxJ	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
YHH3_k127_8643252_0	765952.PUV_26290	3.683e-49	181.0	COG1216@1|root,COG1216@2|Bacteria,2JFSN@204428|Chlamydiae	204428|Chlamydiae	S	Glycosyltransferase like family 2	rfbN	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
YHH3_k127_8698562_1	1392490.JHZX01000001_gene1193	8.097e-26	106.0	2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,1I02M@117743|Flavobacteriia	976|Bacteroidetes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8698562_4	449673.BACSTE_01504	8.507e-07	51.0	2AHEJ@1|root,317RR@2|Bacteria,4P93N@976|Bacteroidetes,2FZC5@200643|Bacteroidia	449673.BACSTE_01504|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8698562_5	1122971.BAME01000164_gene6635	0.0008002	42.0	2A379@1|root,30RNV@2|Bacteria,4PDXA@976|Bacteroidetes,2FW1Y@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8698562_3	1178825.ALIH01000026_gene1866	1.74e-08	56.0	2DEFQ@1|root,2ZMUG@2|Bacteria,4P7CS@976|Bacteroidetes,1IBT1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YHH3_k127_8698562_0	1453505.JASY01000002_gene2818	7.902e-37	147.0	COG1943@1|root,COG1943@2|Bacteria,4NPWC@976|Bacteroidetes,1I28P@117743|Flavobacteriia,2NVCY@237|Flavobacterium	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
YHH3_k127_8698562_2	1150600.ADIARSV_2262	2.192e-21	106.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1ISVQ@117747|Sphingobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
YHH3_k127_8862584_11	656519.Halsa_1570	5.602e-08	57.0	COG0227@1|root,COG0227@2|Bacteria,1UH8Z@1239|Firmicutes,25PYQ@186801|Clostridia,3WC13@53433|Halanaerobiales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
YHH3_k127_8862584_4	309801.trd_0824	1.159e-48	186.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi,27XPA@189775|Thermomicrobia	189775|Thermomicrobia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YHH3_k127_8862584_9	1072685.IX83_00985	2.664e-27	118.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,3T3JW@506|Alcaligenaceae	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
YHH3_k127_8862584_1	765420.OSCT_0247	7.12e-119	391.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi,37503@32061|Chloroflexia	32061|Chloroflexia	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YHH3_k127_8862584_10	1144275.COCOR_05399	2.263e-12	76.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2YVI1@29|Myxococcales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
YHH3_k127_8862584_2	706434.HMPREF9429_01458	3.292e-92	326.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4H3C8@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
YHH3_k127_8862584_6	1128421.JAGA01000003_gene3142	3.476e-38	154.0	COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria	2|Bacteria	LU	DNA recombination-mediator protein A	dprA	-	5.99.1.2	ko:K03168,ko:K04096	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_processg_A
YHH3_k127_8862584_0	1121918.ARWE01000001_gene710	8.641e-196	632.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,43S27@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Bacterial DNA topoisomeraes I ATP-binding domain	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
YHH3_k127_8862584_3	519441.Smon_0213	5.436e-63	227.0	COG0052@1|root,COG0052@2|Bacteria,3795U@32066|Fusobacteria	32066|Fusobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YHH3_k127_8862584_8	580340.Tlie_1183	5.48e-34	136.0	COG0264@1|root,COG0264@2|Bacteria,3TA46@508458|Synergistetes	508458|Synergistetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
YHH3_k127_8862584_7	945713.IALB_0701	5.924e-36	143.0	COG0233@1|root,COG0233@2|Bacteria	2|Bacteria	J	cytoplasmic translational termination	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
YHH3_k127_8862584_5	525904.Tter_1705	1.658e-43	171.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	3.4.21.107	ko:K04771,ko:K11749,ko:K16922	ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Peptidase_M50
YHH3_k127_8875402_0	449447.MAE_17330	1.515e-10	75.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1G0MJ@1117|Cyanobacteria	1117|Cyanobacteria	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B,Trypsin
YHH3_k127_8875402_2	1313172.YM304_09330	3.934e-08	63.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
YHH3_k127_8875402_1	862908.BMS_3450	3.744e-10	61.0	COG0230@1|root,COG0230@2|Bacteria,1Q80X@1224|Proteobacteria,43A9P@68525|delta/epsilon subdivisions,2MTCB@213481|Bdellovibrionales,2XA1B@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
YHH3_k127_8875402_3	110663.KI911558_gene33	5.871e-06	52.0	COG0594@1|root,COG0594@2|Bacteria,1GNHV@1117|Cyanobacteria,1H0ZC@1129|Synechococcus	1117|Cyanobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
YHH3_k127_8879273_0	933262.AXAM01000033_gene1633	1.143e-06	58.0	2EKB4@1|root,33E1H@2|Bacteria,1NJTI@1224|Proteobacteria,432QN@68525|delta/epsilon subdivisions,2WX6K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
YHH3_k127_8888433_0	485913.Krac_7830	9.551e-56	205.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_8888433_1	316274.Haur_4604	2.84e-53	202.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,3755Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_8888433_3	638303.Thal_0136	2.464e-30	134.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YHH3_k127_8888433_4	1121091.AUMP01000017_gene898	1.8e-05	57.0	COG2244@1|root,COG2244@2|Bacteria,1V8VR@1239|Firmicutes,4HNZI@91061|Bacilli	91061|Bacilli	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
YHH3_k127_8888433_2	401526.TcarDRAFT_1133	1.305e-33	151.0	COG1807@1|root,COG1807@2|Bacteria,1UY16@1239|Firmicutes,4H35V@909932|Negativicutes	909932|Negativicutes	M	dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_8917409_0	406327.Mevan_1221	5.852e-29	122.0	COG0475@1|root,arCOG01955@2157|Archaea,2XWIX@28890|Euryarchaeota,23RH1@183939|Methanococci	183939|Methanococci	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
YHH3_k127_8917409_1	293826.Amet_0723	1.733e-26	117.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,36IPK@31979|Clostridiaceae	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
YHH3_k127_8917409_2	517417.Cpar_1462	2.567e-05	56.0	2CIPC@1|root,2Z9HB@2|Bacteria	2|Bacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
YHH3_k127_8977855_5	360911.EAT1b_0889	1.013e-06	52.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,3WF8V@539002|Bacillales incertae sedis	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpB	GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
YHH3_k127_8977855_1	552811.Dehly_0966	1.109e-84	291.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi,34CMR@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YHH3_k127_8977855_3	747365.Thena_1527	1.43e-23	104.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,42H2T@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
YHH3_k127_8977855_4	1028806.GGE_0951	8.348e-15	85.0	COG0697@1|root,COG0697@2|Bacteria,1R89I@1224|Proteobacteria,1SZQ7@1236|Gammaproteobacteria,1Y8H5@135625|Pasteurellales	135625|Pasteurellales	EG	drug metabolite transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YHH3_k127_8977855_2	1382306.JNIM01000001_gene3418	3.561e-54	197.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
YHH3_k127_8977855_0	401526.TcarDRAFT_1349	7.86e-130	428.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H206@909932|Negativicutes	909932|Negativicutes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
YHH3_k127_9003546_1	292459.STH1180	9.453e-14	79.0	COG0681@1|root,COG0681@2|Bacteria,1V2HE@1239|Firmicutes,24R2U@186801|Clostridia	186801|Clostridia	U	Signal peptidase I	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
YHH3_k127_9003546_0	1385511.N783_06355	6.753e-16	92.0	COG1502@1|root,COG1502@2|Bacteria,1VSU5@1239|Firmicutes,4HTP4@91061|Bacilli,2Y9A5@289201|Pontibacillus	91061|Bacilli	I	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,PLDc_2
YHH3_k127_9291686_0	1306174.JODP01000032_gene4027	6.431e-37	156.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
YHH3_k127_9319722_5	1223544.GSI01S_21_00200	1.345e-26	110.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4GEEE@85026|Gordoniaceae	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YHH3_k127_9319722_0	1382356.JQMP01000003_gene1341	1.076e-205	653.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi,27Y1U@189775|Thermomicrobia	189775|Thermomicrobia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YHH3_k127_9319722_6	391587.KAOT1_19557	4.502e-11	73.0	COG1708@1|root,COG1708@2|Bacteria,4NPRU@976|Bacteroidetes,1I105@117743|Flavobacteriia	976|Bacteroidetes	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YHH3_k127_9319722_3	644966.Tmar_2073	1.288e-33	134.0	COG0328@1|root,COG0328@2|Bacteria,1VAJW@1239|Firmicutes,24NJ8@186801|Clostridia	186801|Clostridia	L	PFAM ribonuclease H	rnhA	-	3.1.26.4	ko:K03469,ko:K06864	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
YHH3_k127_9319722_1	70448.A0A096PAI7	5.141e-43	182.0	COG0451@1|root,KOG1429@2759|Eukaryota,37K7R@33090|Viridiplantae,34J0G@3041|Chlorophyta	3041|Chlorophyta	GM	Male sterility protein	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YHH3_k127_9319722_2	926550.CLDAP_22720	3.309e-41	176.0	COG0451@1|root,COG0451@2|Bacteria,2G74B@200795|Chloroflexi	200795|Chloroflexi	GM	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
YHH3_k127_9319722_7	485913.Krac_0136	1.036e-10	71.0	COG3451@1|root,COG3451@2|Bacteria	2|Bacteria	U	multi-organism process	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
YHH3_k127_9319722_4	263358.VAB18032_15900	2.834e-28	122.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria,4DBKR@85008|Micromonosporales	201174|Actinobacteria	U	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
YHH3_k127_9328970_2	1243664.CAVL020000006_gene4905	7.127e-18	92.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,1ZH4N@1386|Bacillus	91061|Bacilli	L	COG1555 DNA uptake protein and related DNA-binding proteins	comEA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
YHH3_k127_9328970_3	1414720.CBYM010000001_gene908	1.27e-09	63.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,24QZK@186801|Clostridia,36JJV@31979|Clostridiaceae	186801|Clostridia	K	regulatory protein, arsR	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
YHH3_k127_9328970_4	944481.JAFP01000001_gene1432	2.475e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1PFUI@1224|Proteobacteria,42W2K@68525|delta/epsilon subdivisions,2WRN3@28221|Deltaproteobacteria,2M7CH@213113|Desulfurellales	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_19,TPR_8
YHH3_k127_9328970_0	1128398.Curi_c19810	1.193e-100	340.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,268DD@186813|unclassified Clostridiales	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
YHH3_k127_9328970_1	926550.CLDAP_04380	2.87e-38	154.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
YHH3_k127_9383654_2	1123376.AUIU01000005_gene1221	5.558e-61	216.0	COG0522@1|root,COG0522@2|Bacteria,3J0IC@40117|Nitrospirae	40117|Nitrospirae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
YHH3_k127_9383654_5	1410630.JNKP01000006_gene182	3.531e-36	141.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,27M7M@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YHH3_k127_9383654_4	197221.22293824	2.149e-38	147.0	COG0099@1|root,COG0099@2|Bacteria,1G5S9@1117|Cyanobacteria	1117|Cyanobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YHH3_k127_9383654_7	880073.Calab_2149	6.473e-13	69.0	COG0257@1|root,COG0257@2|Bacteria,2NQ8V@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
YHH3_k127_9383654_6	857290.HMPREF9156_00622	9.783e-20	91.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4D16H@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
YHH3_k127_9383654_1	706587.Desti_5519	1.503e-112	377.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2MQ90@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
YHH3_k127_9383654_8	7260.FBpp0244194	5.604e-10	68.0	KOG2352@1|root,KOG2352@2759|Eukaryota,38ZV1@33154|Opisthokonta,3BDCZ@33208|Metazoa,3CXUJ@33213|Bilateria,41U7Y@6656|Arthropoda,3SK8I@50557|Insecta,450EH@7147|Diptera,45QN2@7214|Drosophilidae	33208|Metazoa	E	Methyltransferase activity. It is involved in the biological process described with metabolic process	METTL13	GO:0003674,GO:0005488,GO:0005515	-	ko:K08513	ko04130,map04130	-	-	-	ko00000,ko00001,ko04131	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Spermine_synth
YHH3_k127_9383654_3	1123371.ATXH01000009_gene1071	1.525e-50	188.0	COG1968@1|root,COG1968@2|Bacteria,2GHT2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	V	Bacitracin resistance protein BacA	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
YHH3_k127_9383654_0	373903.Hore_16440	1.592e-233	749.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3WAH3@53433|Halanaerobiales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YHH3_k127_9455775_1	42256.RradSPS_1511	2.245e-14	80.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CQNS@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
YHH3_k127_9455775_0	634956.Geoth_3871	1.554e-102	346.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,4HB9A@91061|Bacilli,1WFN1@129337|Geobacillus	91061|Bacilli	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
YHH3_k127_9725250_1	555079.Toce_0147	1.156e-71	252.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,42FI6@68295|Thermoanaerobacterales	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YHH3_k127_9725250_5	1155718.KB891885_gene6392	1.835e-25	111.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria	201174|Actinobacteria	J	ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
YHH3_k127_9725250_3	1122602.ATXP01000001_gene933	3.899e-41	155.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,1W8R8@1268|Micrococcaceae	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YHH3_k127_9725250_4	608506.COB47_1840	3.08e-26	112.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,42G8M@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
YHH3_k127_9725250_6	1408321.JNJD01000007_gene584	0.0005888	46.0	COG1395@1|root,COG1395@2|Bacteria,1UY6T@1239|Firmicutes,24FX9@186801|Clostridia,27JCB@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Desulfoferrodox,HTH_3
YHH3_k127_9725250_2	1120973.AQXL01000116_gene311	7.971e-47	179.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,2789Y@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
YHH3_k127_9725250_0	1461582.BN1048_01831	1.734e-101	358.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,4GX63@90964|Staphylococcaceae	91061|Bacilli	O	ATP-dependent Clp protease, ATP-binding subunit ClpC	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YHH3_k127_9740252_2	1235800.C819_00230	1.074e-14	85.0	COG5662@1|root,COG5662@2|Bacteria,1UHWV@1239|Firmicutes,24JF8@186801|Clostridia,27UJP@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
YHH3_k127_9740252_0	37659.JNLN01000001_gene2044	2.412e-81	278.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,24HDS@186801|Clostridia,36FJX@31979|Clostridiaceae	186801|Clostridia	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
YHH3_k127_9740252_1	1173023.KE650771_gene2475	2.571e-52	204.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_9804145_1	1174528.JH992898_gene4741	9.318e-28	119.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YHH3_k127_9804145_0	1089550.ATTH01000001_gene2109	3.452e-100	336.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1FIUF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YHH3_k127_9992961_1	457570.Nther_1287	1.917e-95	334.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia	186801|Clostridia	L	Single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
YHH3_k127_9992961_3	1382356.JQMP01000003_gene2165	2.588e-68	243.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi,27Y1D@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YHH3_k127_9992961_2	747365.Thena_0155	7.969e-86	301.0	COG0342@1|root,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,42F9I@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YHH3_k127_9992961_6	1267533.KB906736_gene1397	2.858e-23	106.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07061	-	-	-	-	ko00000,ko02048	-	-	-	NTP_transf_2
YHH3_k127_9992961_4	935948.KE386494_gene713	8.196e-45	178.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia,42GPK@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
YHH3_k127_9992961_5	748449.Halha_0144	6.653e-36	141.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3WAS0@53433|Halanaerobiales	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
YHH3_k127_9992961_0	1229780.BN381_250056	2.084e-140	471.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,3UW8P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
## 598 queries scanned
## Total time (seconds): 11.676255226135254
## Rate: 51.22 q/s