## Mon Mar 17 21:14:42 2025
## emapper-2.1.9
## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/YYD2_bin.11.fa -m mmseqs --itype genome -o YYD2_bin.11 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/YYD2_bin.11 --cpu 8
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YYD2_k127_1000624_1	1105031.HMPREF1141_1817	7.335e-20	93.0	COG3293@1|root,COG3293@2|Bacteria,1W1CP@1239|Firmicutes,252HJ@186801|Clostridia	186801|Clostridia	L	This gene contains a nucleotide ambiguity which may be the result of a sequencing error	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
YYD2_k127_1000624_0	192952.MM_2231	3.833e-33	134.0	COG3293@1|root,arCOG03506@2157|Archaea	2157|Archaea	L	Transposase DDE domain	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF4096
YYD2_k127_1028289_0	457421.CBFG_01250	9.802e-20	92.0	COG4021@1|root,COG4021@2|Bacteria,1UVX1@1239|Firmicutes,24DQH@186801|Clostridia	186801|Clostridia	S	Thg1 C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thg1,Thg1C
YYD2_k127_1044354_1	1459636.NTE_00019	1.76e-19	90.0	COG0527@1|root,arCOG00861@2157|Archaea,41SFK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
YYD2_k127_1044354_0	1459636.NTE_00030	6.823e-118	388.0	COG1819@1|root,arCOG01393@2157|Archaea,41T16@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
YYD2_k127_1045741_4	1459636.NTE_02845	3.426e-33	134.0	COG3398@1|root,arCOG02611@2157|Archaea,41T7Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
YYD2_k127_1045741_6	1459636.NTE_00132	3.026e-23	108.0	COG3794@1|root,arCOG02926@2157|Archaea,41TAN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
YYD2_k127_1045741_3	1459636.NTE_03337	2.964e-37	143.0	COG1733@1|root,arCOG01057@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
YYD2_k127_1045741_2	1459636.NTE_02711	2.638e-50	186.0	COG3224@1|root,arCOG08661@2157|Archaea	2157|Archaea	S	Antibiotic biosynthesis monooxygenase	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
YYD2_k127_1045741_1	1173024.KI912149_gene5922	1.25e-120	395.0	COG1741@1|root,COG1741@2|Bacteria,1G41Z@1117|Cyanobacteria,1JJVK@1189|Stigonemataceae	1117|Cyanobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
YYD2_k127_1045741_0	192952.MM_0742	1.966e-129	423.0	COG0798@1|root,arCOG02190@2157|Archaea,2XTQC@28890|Euryarchaeota	28890|Euryarchaeota	P	COG0798 Arsenite efflux pump ACR3 and related permeases	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
YYD2_k127_1045741_5	1459636.NTE_00881	9.538e-25	111.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD2_k127_1046329_0	756883.Halar_1997	3.954e-21	100.0	COG0529@1|root,arCOG01040@2157|Archaea	2157|Archaea	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860,ko:K07028	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_33,APS_kinase
YYD2_k127_1049572_0	1459636.NTE_01510	3.588e-28	126.0	arCOG02362@1|root,arCOG02362@2157|Archaea	1459636.NTE_01510|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_105061_1	1459636.NTE_00711	1.025e-86	292.0	COG0081@1|root,arCOG04289@2157|Archaea,41SHF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds directly to 23S rRNA. Probably involved in E site tRNA release	rpl1	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
YYD2_k127_105061_0	1459636.NTE_02020	7.247e-124	406.0	COG0530@1|root,arCOG02881@2157|Archaea	2157|Archaea	P	COG0530 Ca2 Na antiporter	nce1	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
YYD2_k127_1060867_0	1459636.NTE_03227	1.435e-09	59.0	arCOG07262@1|root,arCOG07262@2157|Archaea	2157|Archaea	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YYD2_k127_1082806_1	1459636.NTE_02738	1.433e-35	136.0	COG1384@1|root,arCOG00485@2157|Archaea	1459636.NTE_02738|-	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1082806_2	1459636.NTE_03299	5.335e-30	123.0	arCOG08025@1|root,arCOG08025@2157|Archaea,41STV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
YYD2_k127_1082806_0	1459636.NTE_03298	3.762e-50	185.0	arCOG08024@1|root,arCOG08024@2157|Archaea,41SRU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
YYD2_k127_109058_1	1459636.NTE_02169	1.299e-104	347.0	COG0151@1|root,arCOG04415@2157|Archaea,41SB3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YYD2_k127_109058_2	999411.HMPREF1092_02322	2.565e-32	133.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,36JPF@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
YYD2_k127_109058_0	1459636.NTE_02167	5.04e-105	347.0	COG2759@1|root,arCOG04538@2157|Archaea,41S6B@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
YYD2_k127_1099543_0	706587.Desti_4763	5.462e-12	75.0	COG3025@1|root,COG3025@2|Bacteria	2|Bacteria	S	triphosphatase activity	ygiF	-	3.6.1.25	ko:K18446	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,CYTH
YYD2_k127_111663_0	1459636.NTE_03481	1.004e-123	409.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
YYD2_k127_1137354_0	671143.DAMO_2372	5.204e-106	361.0	COG0778@1|root,COG0778@2|Bacteria,2NPP2@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YYD2_k127_1175066_0	1459636.NTE_01196	9.405e-107	351.0	COG4742@1|root,arCOG04362@2157|Archaea,41SGE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
YYD2_k127_1175066_1	1459636.NTE_01195	9.676e-32	124.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01195|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1179525_0	990073.ATHU01000001_gene405	1.183e-08	63.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2YNF8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flgR	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_1204976_1	1459636.NTE_03258	4.107e-21	94.0	arCOG10546@1|root,arCOG10546@2157|Archaea,41SRD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1204976_0	1459636.NTE_03308	9.375e-56	202.0	COG1515@1|root,arCOG00929@2157|Archaea	2157|Archaea	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
YYD2_k127_1215436_1	1459636.NTE_02554	6.619e-14	72.0	COG1143@1|root,arCOG01543@2157|Archaea,41SGW@651137|Thaumarchaeota	651137|Thaumarchaeota	C	4Fe-4S binding domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_4
YYD2_k127_1215436_0	1459636.NTE_00560	1.104e-24	106.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1227060_0	1459636.NTE_01185	2.267e-121	393.0	COG0535@1|root,arCOG00938@2157|Archaea,41SXS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
YYD2_k127_1233699_1	1459636.NTE_00871	2.884e-51	191.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD2_k127_1233699_0	864702.OsccyDRAFT_1804	3.642e-177	570.0	COG0793@1|root,COG0793@2|Bacteria,1G3PU@1117|Cyanobacteria,1HE19@1150|Oscillatoriales	1117|Cyanobacteria	E	Periplasmic protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
YYD2_k127_1235180_3	1459636.NTE_03016	4.78e-79	274.0	COG0018@1|root,arCOG00487@2157|Archaea,41SAI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YYD2_k127_1235180_2	1459636.NTE_03013	8.824e-111	364.0	COG2519@1|root,arCOG00978@2157|Archaea,41SEF@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	tRNA methyltransferase complex GCD14 subunit	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14
YYD2_k127_1235180_1	1459636.NTE_00842	2.392e-124	405.0	COG0613@1|root,arCOG00302@2157|Archaea,41S5J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP_C
YYD2_k127_1235180_4	1459636.NTE_03470	0.0001665	45.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD2_k127_1235180_0	1459636.NTE_02407	8.235e-166	536.0	COG1331@1|root,arCOG02007@2157|Archaea,41SHZ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
YYD2_k127_1235843_0	1459636.NTE_01295	1.185e-137	448.0	COG1415@1|root,arCOG04253@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF763)	-	-	-	ko:K09003	-	-	-	-	ko00000	-	-	-	DUF763
YYD2_k127_1236786_0	1459636.NTE_00795	3.576e-96	325.0	COG1055@1|root,arCOG00238@2157|Archaea,41SXH@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
YYD2_k127_1236786_1	1459636.NTE_03481	3.881e-32	128.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
YYD2_k127_1266484_0	1459636.NTE_03025	9.041e-249	779.0	COG0060@1|root,arCOG00807@2157|Archaea,41SFF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
YYD2_k127_1273905_0	1459636.NTE_03154	2.458e-72	245.0	COG1601@1|root,arCOG01640@2157|Archaea,41STZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translation initiation factor	-	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	eIF-5_eIF-2B
YYD2_k127_1273905_1	1459636.NTE_03150	8.483e-45	166.0	COG0526@1|root,arCOG01972@2157|Archaea	2157|Archaea	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YYD2_k127_1275347_0	1459636.NTE_01711	1.066e-151	495.0	COG0277@1|root,arCOG00337@2157|Archaea,41T0E@651137|Thaumarchaeota	651137|Thaumarchaeota	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
YYD2_k127_1275347_1	267608.RSp0074	4.938e-12	72.0	2E3IT@1|root,32YH8@2|Bacteria,1N8T8@1224|Proteobacteria,2VXM9@28216|Betaproteobacteria,1K75D@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1283288_0	1459636.NTE_00560	1.978e-28	120.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1283288_1	879212.DespoDRAFT_03292	0.0001425	47.0	COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MJ2F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,PAS_8,PAS_9,Response_reg
YYD2_k127_1289103_0	1459636.NTE_00041	1.747e-107	355.0	COG0704@1|root,arCOG00318@2157|Archaea,41SC5@651137|Thaumarchaeota	2157|Archaea	K	Phosphate uptake regulator	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
YYD2_k127_1289103_1	266117.Rxyl_0820	1.337e-68	243.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4CQ28@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YYD2_k127_1290682_0	273116.14325549	0.0002061	44.0	COG0149@1|root,arCOG01087@2157|Archaea,2XTY3@28890|Euryarchaeota,241RE@183967|Thermoplasmata	183967|Thermoplasmata	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM,ThiG
YYD2_k127_1291295_1	436308.Nmar_0884	7.466e-29	123.0	arCOG10557@1|root,arCOG10557@2157|Archaea,41T1I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1291295_0	1459636.NTE_02001	2.775e-130	422.0	COG1131@1|root,arCOG00194@2157|Archaea	2157|Archaea	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_1291295_2	1459636.NTE_03029	0.0002817	44.0	arCOG08748@1|root,arCOG08748@2157|Archaea,41SV7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1303283_1	391616.OA238_c12030	9.384e-16	81.0	COG2931@1|root,COG2931@2|Bacteria,1N161@1224|Proteobacteria,2UDXT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	type I secretion target repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
YYD2_k127_1303283_0	1459636.NTE_00658	1.634e-27	113.0	arCOG10584@1|root,arCOG10584@2157|Archaea,41SV6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bacterial Fe(2+) trafficking	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
YYD2_k127_1303283_2	1459636.NTE_00657	2.008e-14	79.0	arCOG08772@1|root,arCOG08772@2157|Archaea,41SSX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1325249_4	1459636.NTE_02818	1.591e-05	47.0	COG0154@1|root,arCOG01717@2157|Archaea,41SCW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD2_k127_1325249_3	1231377.C426_0857	8.247e-06	51.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,1YBV9@1357|Lactococcus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
YYD2_k127_1325249_0	1459636.NTE_02820	1.909e-179	572.0	COG0017@1|root,arCOG00406@2157|Archaea,41SBT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	-	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YYD2_k127_1325249_2	521011.Mpal_1345	2.727e-63	228.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
YYD2_k127_1325249_1	1459636.NTE_00914	5.766e-139	458.0	COG1061@1|root,arCOG00874@2157|Archaea,41SW0@651137|Thaumarchaeota	2157|Archaea	K	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
YYD2_k127_1332266_0	1459636.NTE_02830	1.051e-19	94.0	COG1073@1|root,arCOG01661@2157|Archaea	2157|Archaea	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
YYD2_k127_1332717_0	1459636.NTE_02328	7.501e-166	531.0	COG0034@1|root,arCOG00093@2157|Archaea,41S7N@651137|Thaumarchaeota	2157|Archaea	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
YYD2_k127_1332717_2	1459636.NTE_02329	5.651e-18	87.0	arCOG08657@1|root,arCOG08657@2157|Archaea,41SRB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1332717_1	1459636.NTE_02330	2.202e-31	124.0	arCOG10136@1|root,arCOG10136@2157|Archaea,41T5E@651137|Thaumarchaeota	651137|Thaumarchaeota	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
YYD2_k127_1342764_0	248742.XP_005649230.1	4.485e-14	83.0	COG1409@1|root,KOG1378@2759|Eukaryota	2759|Eukaryota	E	acid phosphatase activity	-	-	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos
YYD2_k127_1352608_0	926549.KI421517_gene2554	8.281e-13	70.0	COG4294@1|root,COG4294@2|Bacteria,4NIZA@976|Bacteroidetes,47K7P@768503|Cytophagia	976|Bacteroidetes	L	UV-endonuclease UvdE	-	-	-	-	-	-	-	-	-	-	-	-	UvdE
YYD2_k127_1356619_1	1459636.NTE_02687	7.006e-117	382.0	COG0037@1|root,arCOG00042@2157|Archaea,41S84@651137|Thaumarchaeota	651137|Thaumarchaeota	D	PP-loop family	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
YYD2_k127_1356619_0	1459636.NTE_02703	6.447e-150	480.0	COG1736@1|root,arCOG04112@2157|Archaea,41SE0@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Diphthamide biosynthesis	-	-	2.5.1.108	ko:K07561	-	-	R10455	RC00021,RC03180	ko00000,ko01000,ko03012	-	-	-	Diphthamide_syn
YYD2_k127_1356619_2	1459636.NTE_03213	4.481e-86	293.0	COG0294@1|root,arCOG02817@2157|Archaea,41SGK@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Pterin binding enzyme	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
YYD2_k127_1359480_0	1459636.NTE_00560	1.739e-33	134.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_135969_0	439481.Aboo_0904	3.224e-122	398.0	COG1228@1|root,arCOG00696@2157|Archaea,2XVAU@28890|Euryarchaeota,3F2Z2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD2_k127_1361854_2	1448389.BAVQ01000002_gene2942	9.389e-26	110.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria	201174|Actinobacteria	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
YYD2_k127_1361854_0	1459636.NTE_03163	2.418e-100	339.0	COG0003@1|root,COG0071@1|root,arCOG01833@2157|Archaea,arCOG02849@2157|Archaea	2157|Archaea	P	Arsenite-activated ATPase ArsA	arsA4	-	3.6.3.16	ko:K01551,ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko01000,ko02000,ko03110	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
YYD2_k127_1361854_1	1459636.NTE_00419	8.072e-42	163.0	COG2968@1|root,arCOG04715@2157|Archaea,41T6R@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
YYD2_k127_1362015_1	1459636.NTE_02306	1.023e-99	331.0	COG0115@1|root,arCOG02297@2157|Archaea,41S5T@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YYD2_k127_1362015_0	1459636.NTE_02307	4.832e-126	412.0	COG0673@1|root,arCOG01622@2157|Archaea,41SZ6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YYD2_k127_1362015_3	436308.Nmar_0246	5.111e-24	106.0	COG2835@1|root,arCOG04124@2157|Archaea,41STB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
YYD2_k127_1362015_2	1459636.NTE_02309	9.045e-73	250.0	COG0110@1|root,arCOG01848@2157|Archaea,41SJ0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YYD2_k127_1376879_2	945713.IALB_1169	1.766e-19	91.0	COG1629@1|root,COG4772@1|root,COG4771@2|Bacteria,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YYD2_k127_1376879_0	436308.Nmar_0987	2.713e-54	201.0	COG1405@1|root,arCOG01981@2157|Archaea,41SYU@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
YYD2_k127_1376879_4	1459636.NTE_00897	3.677e-09	65.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T3X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1376879_3	386456.JQKN01000008_gene1544	2.8e-09	63.0	COG0784@1|root,arCOG06537@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD2_k127_1376879_1	1121121.KB894289_gene2575	4.167e-24	108.0	COG2133@1|root,COG2133@2|Bacteria,1VBUK@1239|Firmicutes,4HKNP@91061|Bacilli,26YMI@186822|Paenibacillaceae	91061|Bacilli	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
YYD2_k127_1380639_0	395961.Cyan7425_3678	2.635e-12	73.0	2E3IT@1|root,32YH8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1384867_0	565033.GACE_0364	2.915e-58	209.0	COG0171@1|root,arCOG00069@2157|Archaea,2XT7M@28890|Euryarchaeota,24632@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
YYD2_k127_1384867_1	517417.Cpar_1355	8.085e-33	138.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
YYD2_k127_1387222_1	1459636.NTE_03327	2.886e-09	62.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1387222_0	1459636.NTE_00533	1.244e-15	86.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BAT,GAF_2,HATPase_c,HTH_10,HisKA,MEDS,PAS_4
YYD2_k127_138737_0	1459636.NTE_01981	3.251e-83	293.0	COG2379@1|root,arCOG04170@2157|Archaea,41SJF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
YYD2_k127_138737_1	391623.TERMP_00290	9.747e-40	158.0	COG0340@1|root,arCOG01940@2157|Archaea,2XSZ5@28890|Euryarchaeota,243TN@183968|Thermococci	183968|Thermococci	H	Biotin protein ligase C terminal domain	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
YYD2_k127_1393582_0	237368.SCABRO_00224	4.065e-133	437.0	COG1524@1|root,COG1524@2|Bacteria,2IXT6@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
YYD2_k127_139542_0	1459636.NTE_01059	0.0	1198.0	COG1201@1|root,arCOG00557@2157|Archaea,41S8P@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
YYD2_k127_139542_1	1459636.NTE_01417	4.012e-141	457.0	COG0301@1|root,arCOG00038@2157|Archaea,41T1A@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
YYD2_k127_139542_2	1459636.NTE_02166	1.704e-06	52.0	arCOG11431@1|root,arCOG11431@2157|Archaea,41T8G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1401123_1	1459636.NTE_02436	7.2e-26	115.0	arCOG02527@1|root,arCOG02527@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NosD
YYD2_k127_1401123_0	523791.Kkor_0590	7.374e-74	259.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1XRBY@135619|Oceanospirillales	135619|Oceanospirillales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD2_k127_1401243_0	436308.Nmar_0735	1.421e-90	316.0	arCOG08801@1|root,arCOG08801@2157|Archaea	2157|Archaea	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1401243_1	1121129.KB903367_gene2936	2.731e-05	51.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,2FMHN@200643|Bacteroidia,22WD9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8
YYD2_k127_1404849_0	1459636.NTE_01046	1.018e-25	107.0	arCOG02240@1|root,arCOG02240@2157|Archaea	2157|Archaea	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase,Tautomerase_2
YYD2_k127_1409079_0	679926.Mpet_0303	1.46e-94	316.0	COG0863@1|root,arCOG00115@2157|Archaea,2XWB2@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
YYD2_k127_1409079_1	1459636.NTE_01553	6.425e-28	118.0	arCOG12283@1|root,arCOG12283@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1409857_1	634498.mru_1957	0.0004207	45.0	COG0011@1|root,arCOG04373@2157|Archaea,2Y1TV@28890|Euryarchaeota	28890|Euryarchaeota	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
YYD2_k127_1409857_0	1459636.NTE_00888	9.347e-29	121.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
YYD2_k127_1415943_1	497964.CfE428DRAFT_2876	1.782e-19	89.0	COG2818@1|root,COG2818@2|Bacteria,46SS9@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
YYD2_k127_1415943_0	1459636.NTE_01667	7.321e-38	145.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1417894_0	1459636.NTE_01289	6.732e-37	144.0	COG3324@1|root,arCOG04946@2157|Archaea	2157|Archaea	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
YYD2_k127_1431067_1	197221.22293973	5.796e-05	52.0	COG2389@1|root,COG2389@2|Bacteria,1G6XV@1117|Cyanobacteria	1117|Cyanobacteria	S	metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2227
YYD2_k127_1431385_3	1459636.NTE_01423	1.124e-24	107.0	COG1986@1|root,arCOG01223@2157|Archaea,41SKV@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cytidylyltransferase-like	-	-	2.7.7.3	ko:K02201	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YYD2_k127_1431385_2	1459636.NTE_01422	1.035e-30	126.0	arCOG08641@1|root,arCOG08641@2157|Archaea,41SU7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1431385_4	1459636.NTE_01421	5.289e-13	72.0	arCOG10585@1|root,arCOG10585@2157|Archaea,41SW6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1431385_0	1459636.NTE_01420	4.946e-187	591.0	COG0180@1|root,arCOG01887@2157|Archaea,41SDK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YYD2_k127_1431385_1	1459636.NTE_01419	4.447e-44	170.0	COG0016@1|root,arCOG00410@2157|Archaea,41S9U@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Phenylalanyl-tRNA synthetase alpha subunit	-	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
YYD2_k127_143635_0	1459636.NTE_01665	4.04e-171	546.0	COG0017@1|root,arCOG00406@2157|Archaea,41S93@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_2,tRNA_anti-codon
YYD2_k127_143635_2	698757.Pogu_0039	2.485e-10	67.0	COG1310@1|root,arCOG01138@2157|Archaea,2XRGC@28889|Crenarchaeota	28889|Crenarchaeota	S	Prokaryotic homologs of the JAB domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
YYD2_k127_143635_1	1459636.NTE_01663	1.268e-24	106.0	COG2237@1|root,COG3794@1|root,arCOG02926@2157|Archaea,arCOG02929@2157|Archaea,arCOG04151@2157|Archaea,41SHN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
YYD2_k127_1464442_4	1459636.NTE_00731	8.132e-156	496.0	COG0137@1|root,arCOG00112@2157|Archaea,41S6K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
YYD2_k127_1464442_11	1459636.NTE_00732	4.834e-22	96.0	arCOG01588@1|root,arCOG01588@2157|Archaea,41SVX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
YYD2_k127_1464442_7	1459636.NTE_00733	1.066e-117	384.0	COG0189@1|root,arCOG01589@2157|Archaea,41SCQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Lysine biosynthesis	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
YYD2_k127_1464442_1	1459636.NTE_00734	2.505e-199	623.0	COG0002@1|root,arCOG00495@2157|Archaea,41S8R@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily	lysY	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YYD2_k127_1464442_6	1459636.NTE_00735	2.747e-122	397.0	COG0548@1|root,arCOG00862@2157|Archaea,41SFB@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis)	lysZ	-	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
YYD2_k127_1464442_2	1459636.NTE_00736	7.982e-190	599.0	COG4992@1|root,arCOG00914@2157|Archaea,41SC8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lysJ	-	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YYD2_k127_1464442_9	1229909.NSED_07170	2.24e-39	151.0	COG1522@1|root,arCOG01580@2157|Archaea,41SNE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
YYD2_k127_1464442_0	1459636.NTE_01584	1.188e-218	683.0	COG0119@1|root,arCOG02092@2157|Archaea,41S7Y@651137|Thaumarchaeota	651137|Thaumarchaeota	E	HMGL-like	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
YYD2_k127_1464442_10	1459636.NTE_01583	7.406e-23	98.0	arCOG01588@1|root,arCOG01588@2157|Archaea,41STK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
YYD2_k127_1464442_5	1459636.NTE_01582	4.642e-127	412.0	COG0189@1|root,arCOG01589@2157|Archaea,41SE8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Lysine biosynthesis	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
YYD2_k127_1464442_3	1459636.NTE_01581	7.508e-178	563.0	COG0624@1|root,arCOG01107@2157|Archaea,41SAX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	M20_dimer,Peptidase_M20
YYD2_k127_1464442_8	1459636.NTE_01580	1.033e-110	369.0	COG1798@1|root,COG1849@1|root,arCOG01224@2157|Archaea,arCOG04161@2157|Archaea,41SC2@651137|Thaumarchaeota	651137|Thaumarchaeota	H	diphthine synthase	-	-	2.1.1.98	ko:K20215	-	-	R04481,R08468,R08469,R10306	RC00003,RC00190,RC01155,RC02136,RC02308	ko00000,ko01000	-	-	-	DUF357,TP_methylase
YYD2_k127_1464442_12	439481.Aboo_0440	3.284e-18	93.0	COG0467@1|root,arCOG01178@2157|Archaea,2Y0GM@28890|Euryarchaeota,3F33E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	PFAM GvpD gas vesicle	-	-	-	-	-	-	-	-	-	-	-	-	GvpD
YYD2_k127_1466386_0	44689.DDB0189828	2.781e-26	117.0	KOG0909@1|root,KOG0909@2759|Eukaryota,3XC3A@554915|Amoebozoa	554915|Amoebozoa	O	Transglutaminase/protease-like homologues	-	-	3.5.1.52	ko:K01456	ko04141,map04141	-	-	-	ko00000,ko00001,ko01000	-	-	-	Lectin_legB,Transglut_core
YYD2_k127_1470700_1	1459636.NTE_02794	6.432e-104	341.0	COG5253@1|root,arCOG04169@2157|Archaea,41S9X@651137|Thaumarchaeota	651137|Thaumarchaeota	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	Plug_translocon,SecY
YYD2_k127_1470700_4	1459636.NTE_02793	4.424e-50	184.0	COG2019@1|root,arCOG01039@2157|Archaea,41SK7@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the archaeal adenylate kinase family	adkA	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
YYD2_k127_1470700_2	1459636.NTE_02792	1.084e-79	270.0	COG1422@1|root,arCOG02673@2157|Archaea,41SNR@651137|Thaumarchaeota	651137|Thaumarchaeota	U	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF106
YYD2_k127_1470700_3	1459636.NTE_02791	1.561e-59	211.0	COG1102@1|root,arCOG01037@2157|Archaea,41SKS@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
YYD2_k127_1470700_0	1459636.NTE_02790	5.392e-137	443.0	COG0130@1|root,arCOG00987@2157|Archaea,41S8E@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs	truB	-	-	ko:K11131	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03032	-	-	-	DKCLD,PUA,TruB_C_2,TruB_N
YYD2_k127_148464_0	398767.Glov_0114	7.917e-10	63.0	COG0500@1|root,COG2226@2|Bacteria,1QZV0@1224|Proteobacteria,43CPF@68525|delta/epsilon subdivisions,2WS28@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD2_k127_1496161_0	693661.Arcve_0744	8.44e-15	76.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,245UG@183980|Archaeoglobi	183980|Archaeoglobi	O	AAA family ATPase, CDC48 subfamily	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
YYD2_k127_1522282_1	1229909.NSED_01775	1.769e-13	77.0	COG2314@1|root,arCOG01917@1|root,arCOG01917@2157|Archaea,arCOG03293@2157|Archaea	2157|Archaea	O	PFAM TM2 domain containing protein	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DZR,DnaJ,TM2
YYD2_k127_1522282_0	1459636.NTE_01729	9.032e-19	90.0	COG1522@1|root,arCOG01585@2157|Archaea,41T4Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal TRASH domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc_trans_TRASH,HTH_AsnC-type
YYD2_k127_1526121_0	1123518.ARWI01000001_gene1948	5.208e-162	528.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales	72273|Thiotrichales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YYD2_k127_1528959_1	68170.KL590558_gene5388	2.817e-13	79.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_1528959_0	219305.MCAG_00296	5.034e-53	210.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4DAW3@85008|Micromonosporales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
YYD2_k127_1530510_1	1459636.NTE_03327	4.285e-14	79.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1530510_0	1459636.NTE_01258	5.406e-24	108.0	arCOG08663@1|root,arCOG08663@2157|Archaea,41SR2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1531866_0	484770.UFO1_2112	1.905e-102	340.0	COG1864@1|root,COG1864@2|Bacteria,1UKQ1@1239|Firmicutes	1239|Firmicutes	F	DNA/RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
YYD2_k127_1535851_0	1459636.NTE_00230	2.092e-23	107.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
YYD2_k127_1538132_1	1459636.NTE_00881	7.696e-16	82.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD2_k127_1538132_0	926550.CLDAP_21610	1.466e-146	473.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YYD2_k127_1539662_0	1459636.NTE_01508	5.062e-07	57.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1539875_0	1459636.NTE_01104	5.328e-91	305.0	COG1136@1|root,arCOG00922@2157|Archaea,41T2R@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
YYD2_k127_1539875_1	1459636.NTE_01103	2.812e-44	177.0	COG1361@1|root,arCOG02080@2157|Archaea,41T6N@651137|Thaumarchaeota	651137|Thaumarchaeota	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1552828_2	1229909.NSED_01010	4.603e-06	53.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD2_k127_1552828_0	1459636.NTE_02704	1.204e-25	106.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1555277_0	1459636.NTE_01667	1.139e-41	155.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1555277_1	1459636.NTE_01195	1.389e-24	104.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01195|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1556164_1	1459636.NTE_02077	3e-70	240.0	COG0426@1|root,arCOG00509@2157|Archaea	2157|Archaea	C	flavodoxin nitric oxide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD2_k127_1556164_0	1459636.NTE_00754	1.933e-99	328.0	COG5588@1|root,arCOG11393@2157|Archaea	1459636.NTE_00754|-	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1557450_1	403833.Pmob_1491	6.317e-25	106.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10109,ko:K10189,ko:K15771,ko:K17245,ko:K17316	ko02010,map02010	M00194,M00198,M00199,M00207,M00491,M00601,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22,3.A.1.1.24,3.A.1.1.3,3.A.1.1.30,3.A.1.1.4,3.A.1.1.40	-	-	BPD_transp_1
YYD2_k127_1557450_0	373903.Hore_22980	1.774e-88	300.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,24G0B@186801|Clostridia	186801|Clostridia	P	-transport system	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
YYD2_k127_1574786_4	1459636.NTE_00421	5.579e-40	149.0	COG0760@1|root,arCOG07441@2157|Archaea,41SSK@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
YYD2_k127_1574786_3	1459636.NTE_01719	6.454e-44	163.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41T4V@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
YYD2_k127_1574786_0	1459636.NTE_01648	4.18e-189	594.0	COG0535@1|root,arCOG00938@2157|Archaea	2157|Archaea	P	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD2_k127_1574786_5	1459636.NTE_01042	4.077e-36	145.0	arCOG08812@1|root,arCOG08812@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1574786_2	1229909.NSED_09845	2.218e-86	292.0	COG0300@1|root,arCOG01263@2157|Archaea,41SXQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
YYD2_k127_1574786_1	1459636.NTE_02924	1.405e-182	587.0	COG1205@1|root,arCOG00555@2157|Archaea,41SZS@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
YYD2_k127_15786_1	1347392.CCEZ01000049_gene1580	3.742e-08	61.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	prdR	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
YYD2_k127_15786_0	1459636.NTE_01989	6.082e-54	193.0	COG1832@1|root,arCOG04227@2157|Archaea,41SMT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
YYD2_k127_1583628_1	1459636.NTE_02682	4.637e-40	158.0	arCOG08818@1|root,arCOG08818@2157|Archaea,41SVV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1583628_0	1459636.NTE_02683	3.923e-69	237.0	COG0177@1|root,arCOG00459@2157|Archaea,41SFM@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YYD2_k127_1585208_3	1459636.NTE_02594	1.103e-25	106.0	COG0052@1|root,arCOG04245@2157|Archaea,41SG7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS2 family	rps2	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YYD2_k127_1585208_2	1229909.NSED_00885	9.583e-67	237.0	COG1355@1|root,arCOG01728@2157|Archaea,41S9D@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
YYD2_k127_1585208_1	1459636.NTE_02597	2.087e-73	259.0	COG1577@1|root,arCOG01028@2157|Archaea,41SKC@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YYD2_k127_1585208_0	1229909.NSED_01515	3.857e-79	271.0	COG1608@1|root,arCOG00860@2157|Archaea,41SI4@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Amino acid kinase family	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YYD2_k127_1587159_1	1245475.ANAE01000079_gene3537	2.068e-09	59.0	COG1977@1|root,COG1977@2|Bacteria,2GQM9@201174|Actinobacteria	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
YYD2_k127_1587159_0	1313421.JHBV01000008_gene4485	1.066e-15	78.0	COG3586@1|root,COG3586@2|Bacteria,4NERW@976|Bacteroidetes	976|Bacteroidetes	L	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1590976_0	192952.MM_2642	6.001e-12	74.0	COG0668@1|root,arCOG01568@2157|Archaea,2XUHN@28890|Euryarchaeota,2N9I0@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YYD2_k127_1590976_1	1123376.AUIU01000013_gene1879	7.901e-05	46.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspX	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564	-	ko:K06335,ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YYD2_k127_160295_0	517417.Cpar_1355	3.533e-49	183.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
YYD2_k127_1604589_0	1048834.TC41_0139	4.7e-78	280.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,278QY@186823|Alicyclobacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
YYD2_k127_16083_0	1459636.NTE_03283	4.388e-165	535.0	COG1293@1|root,arCOG01695@2157|Archaea,41SB0@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
YYD2_k127_16083_5	1459636.NTE_03265	1.323e-15	80.0	arCOG10415@1|root,arCOG10415@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_16083_3	1459636.NTE_03264	1.346e-70	243.0	COG2242@1|root,arCOG00977@2157|Archaea,41SID@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7	cbiT	-	2.1.1.196	ko:K02191	ko00860,map00860	-	R05813,R07774	RC00003,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	Methyltransf_31
YYD2_k127_16083_2	1131266.ARWQ01000001_gene1298	4.738e-73	253.0	COG2243@1|root,arCOG00648@2157|Archaea,41SGJ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
YYD2_k127_16083_1	1459636.NTE_00412	2.623e-116	379.0	COG2875@1|root,arCOG00645@2157|Archaea,41SE7@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
YYD2_k127_16083_4	1459636.NTE_01076	1.62e-44	170.0	COG1451@1|root,arCOG02625@2157|Archaea,41TA5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
YYD2_k127_16083_6	1459636.NTE_03208	2.196e-12	67.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
YYD2_k127_1625556_2	1459636.NTE_01024	1.242e-24	113.0	arCOG03788@1|root,arCOG03788@2157|Archaea,41T96@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1625556_1	1459636.NTE_02478	5.097e-37	143.0	COG0836@1|root,arCOG02427@2157|Archaea	2157|Archaea	M	TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0229	MannoseP_isomer,NTP_transferase
YYD2_k127_1625556_5	643867.Ftrac_0495	4.647e-05	53.0	COG2374@1|root,COG4447@1|root,COG4733@1|root,COG4886@1|root,COG2374@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
YYD2_k127_1631838_0	1131266.ARWQ01000008_gene303	4.61e-09	58.0	COG0726@1|root,arCOG02877@2157|Archaea	2157|Archaea	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
YYD2_k127_1631838_1	266117.Rxyl_2895	5.964e-05	49.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria,4CTPZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
YYD2_k127_16455_2	1459636.NTE_02590	7.891e-35	134.0	COG1644@1|root,arCOG04244@2157|Archaea,41SPN@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoN	-	2.7.7.6	ko:K03058	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_N
YYD2_k127_16455_0	1459636.NTE_02591	1.173e-171	547.0	COG0148@1|root,arCOG01169@2157|Archaea,41SE9@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
YYD2_k127_16455_1	1459636.NTE_02594	1.948e-107	353.0	COG0052@1|root,arCOG04245@2157|Archaea,41SG7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS2 family	rps2	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YYD2_k127_16455_3	1229909.NSED_00885	6.523e-10	62.0	COG1355@1|root,arCOG01728@2157|Archaea,41S9D@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
YYD2_k127_164799_4	1459636.NTE_02314	8.018e-28	115.0	COG1324@1|root,arCOG04231@2157|Archaea,41SR4@651137|Thaumarchaeota	651137|Thaumarchaeota	P	PFAM CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
YYD2_k127_164799_1	1459636.NTE_02315	5.866e-123	403.0	COG1537@1|root,arCOG01741@2157|Archaea,41S6V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity	pelA	-	-	ko:K06965	ko03015,map03015	-	-	-	ko00000,ko00001	-	-	-	eRF1_1,eRF1_3
YYD2_k127_164799_2	1229909.NSED_00250	1.034e-50	183.0	arCOG08723@1|root,arCOG08723@2157|Archaea,41SPX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_164799_3	1459636.NTE_02002	1.046e-33	132.0	arCOG10524@1|root,arCOG10524@2157|Archaea,41SVP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_164799_0	1459636.NTE_02324	2.07e-131	428.0	COG1164@1|root,arCOG04758@2157|Archaea	2157|Archaea	E	oligoendopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
YYD2_k127_1662409_1	1459636.NTE_00085	7.963e-108	353.0	COG1311@1|root,arCOG04455@2157|Archaea,41T0D@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	-	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B
YYD2_k127_1662409_0	1459636.NTE_00084	2.153e-138	446.0	COG1474@1|root,arCOG00467@2157|Archaea,41SED@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22,Cdc6_C
YYD2_k127_1664808_3	1459636.NTE_02162	1.639e-09	58.0	COG2126@1|root,arCOG04126@2157|Archaea,41T9V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl37e	-	-	ko:K02922	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37e
YYD2_k127_1664808_1	1459636.NTE_02161	9.691e-34	130.0	COG1958@1|root,arCOG00998@2157|Archaea,41SU9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	snRNP Sm proteins	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
YYD2_k127_1664808_0	1459636.NTE_02160	8.242e-65	229.0	COG1402@1|root,arCOG04536@2157|Archaea,41SNC@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
YYD2_k127_1664808_2	1459636.NTE_02159	1.717e-30	121.0	COG0788@1|root,arCOG02826@2157|Archaea,41S78@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Formyl transferase	-	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT_6,Formyl_trans_N
YYD2_k127_1670819_1	565033.GACE_1578	1.193e-21	96.0	COG0144@1|root,arCOG00973@2157|Archaea,2XUFZ@28890|Euryarchaeota,245P3@183980|Archaeoglobi	183980|Archaeoglobi	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
YYD2_k127_1670819_0	1459636.NTE_01460	2.015e-32	132.0	COG1374@1|root,arCOG00993@2157|Archaea	2157|Archaea	J	Protein involved in ribosomal biogenesis, contains PUA domain	-	-	-	ko:K07565	-	-	-	-	ko00000,ko03009	-	-	-	UPF0113
YYD2_k127_1675796_3	1459636.NTE_02802	7.115e-71	242.0	COG1944@1|root,arCOG02882@2157|Archaea	2157|Archaea	H	methanogenesis marker protein 1	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
YYD2_k127_1675796_5	1459636.NTE_02803	1.419e-64	227.0	COG3482@1|root,arCOG05002@2157|Archaea	2157|Archaea	S	PFAM TfuA domain protein, core	-	-	-	-	-	-	-	-	-	-	-	-	TfuA
YYD2_k127_1675796_7	1459636.NTE_00739	1.879e-26	113.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T7E@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1675796_4	1459636.NTE_00747	1.098e-66	230.0	COG1632@1|root,arCOG04209@2157|Archaea,41SND@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein L15E	-	-	-	ko:K02877	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L15e
YYD2_k127_1675796_6	1459636.NTE_02403	6.766e-42	160.0	COG0251@1|root,arCOG01630@2157|Archaea,41T4N@651137|Thaumarchaeota	651137|Thaumarchaeota	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
YYD2_k127_1675796_1	1459636.NTE_00750	2.49e-122	400.0	COG0111@1|root,arCOG01754@2157|Archaea,41S8U@651137|Thaumarchaeota	651137|Thaumarchaeota	H	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YYD2_k127_1675796_0	1459636.NTE_01354	2.846e-141	456.0	COG1146@1|root,arCOG04548@2157|Archaea,41SH5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
YYD2_k127_1675796_2	1459636.NTE_02407	2.064e-81	274.0	COG1331@1|root,arCOG02007@2157|Archaea,41SHZ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
YYD2_k127_1686864_1	1459636.NTE_01403	4.642e-92	314.0	COG2132@1|root,arCOG03914@2157|Archaea,41SZT@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
YYD2_k127_1686864_0	635013.TherJR_1270	1.239e-106	363.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,2606T@186807|Peptococcaceae	186801|Clostridia	P	pyridine nucleotide-disulphide oxidoreductase dimerisation	noxE	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
YYD2_k127_1693782_0	1459636.NTE_03097	1.066e-149	487.0	arCOG03664@1|root,arCOG03664@2157|Archaea	2157|Archaea	S	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3
YYD2_k127_1693782_1	1459636.NTE_00433	3.851e-36	143.0	arCOG08765@1|root,arCOG08765@2157|Archaea,41SQJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1700629_2	264198.Reut_B3680	4.559e-31	124.0	COG4257@1|root,COG4257@2|Bacteria,1R448@1224|Proteobacteria,2W139@28216|Betaproteobacteria,1KEAH@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Carboxypeptidase regulatory-like domain	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarboxypepD_reg
YYD2_k127_1700629_1	1459636.NTE_00144	9.794e-53	196.0	arCOG03593@1|root,arCOG03593@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795,PRC
YYD2_k127_1700629_0	1459636.NTE_01099	1.994e-99	330.0	COG1409@1|root,arCOG01153@2157|Archaea,41SF2@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YYD2_k127_1717215_7	1459636.NTE_00826	0.0003371	47.0	COG0805@1|root,arCOG01919@2157|Archaea,41S69@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YYD2_k127_1717215_5	1459636.NTE_02088	2.375e-26	111.0	arCOG11950@1|root,arCOG11950@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	bPH_3
YYD2_k127_1717215_1	1459636.NTE_01027	6.547e-146	473.0	COG1078@1|root,arCOG04430@2157|Archaea,41T0P@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
YYD2_k127_1717215_2	1459636.NTE_01026	1.675e-71	249.0	COG0528@1|root,arCOG00858@2157|Archaea,41T1R@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YYD2_k127_1717215_4	1459636.NTE_01025	3.228e-38	145.0	arCOG08775@1|root,arCOG08775@2157|Archaea,41T9K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1717215_6	1459636.NTE_00825	1.864e-25	113.0	COG1826@1|root,arCOG02694@2157|Archaea,41T8C@651137|Thaumarchaeota	651137|Thaumarchaeota	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
YYD2_k127_1717215_0	1459636.NTE_00824	8.755e-162	517.0	COG1759@1|root,arCOG04346@2157|Archaea,41S79@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Domain of unknown function (DUF1297)	-	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
YYD2_k127_1717215_3	1459636.NTE_02658	1.737e-59	213.0	COG1011@1|root,arCOG02291@2157|Archaea	2157|Archaea	S	hydrolase (HAD superfamily)	hadL	-	3.1.3.18,3.8.1.2,3.8.1.3	ko:K01091,ko:K01560,ko:K01561,ko:K07025	ko00361,ko00625,ko00630,ko01100,ko01110,ko01120,ko01130,map00361,map00625,map00630,map01100,map01110,map01120,map01130	-	R01334,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
YYD2_k127_1798172_0	1459636.NTE_00550	3.908e-156	503.0	COG0655@1|root,COG2146@1|root,arCOG02578@2157|Archaea,arCOG02852@2157|Archaea	2157|Archaea	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
YYD2_k127_1799922_0	1459636.NTE_01927	6.237e-70	248.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1,sCache_3_3
YYD2_k127_1805294_1	1123388.AQWU01000042_gene2111	5.561e-17	83.0	COG1525@1|root,COG1525@2|Bacteria,1WJH4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
YYD2_k127_1807152_0	1459636.NTE_00110	0.0	1033.0	COG0209@1|root,arCOG01917@1|root,arCOG03713@1|root,arCOG01917@2157|Archaea,arCOG03713@2157|Archaea,arCOG04276@2157|Archaea,41SAH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
YYD2_k127_1808223_0	1459636.NTE_01410	4.739e-55	198.0	COG1628@1|root,arCOG00928@2157|Archaea,41SMQ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Protein of unknown function DUF99	-	-	-	ko:K09120	-	-	-	-	ko00000	-	-	-	DUF99
YYD2_k127_1808651_0	374847.Kcr_0237	3.407e-192	614.0	COG4670@1|root,arCOG01986@2157|Archaea	2157|Archaea	I	Acyl CoA acetate 3-ketoacid CoA transferase	-	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
YYD2_k127_1808651_1	1056495.Calag_1483	5.289e-31	136.0	COG0517@1|root,arCOG00600@2157|Archaea,2XQMG@28889|Crenarchaeota	28889|Crenarchaeota	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YYD2_k127_1813774_0	1459636.NTE_00853	5.961e-189	606.0	COG0531@1|root,arCOG00451@1|root,arCOG00009@2157|Archaea,arCOG00451@2157|Archaea,41SYK@651137|Thaumarchaeota	651137|Thaumarchaeota	ET	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
YYD2_k127_1830150_1	413816.BBJP01000013_gene959	3.225e-22	102.0	COG0529@1|root,arCOG01040@2157|Archaea,2XWW4@28890|Euryarchaeota,23V8B@183963|Halobacteria	183963|Halobacteria	P	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
YYD2_k127_1830150_0	194439.CT0831	6.174e-28	118.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1FD6X@1090|Chlorobi	1090|Chlorobi	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
YYD2_k127_1831700_0	1459636.NTE_00389	7.934e-137	447.0	COG0475@1|root,arCOG01955@2157|Archaea,41SG1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
YYD2_k127_1831700_4	1459636.NTE_01667	1.461e-36	143.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1831700_5	1459636.NTE_00966	1.682e-24	103.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1831700_1	1459636.NTE_02506	8.749e-119	394.0	arCOG01390@1|root,arCOG01390@2157|Archaea,41S7Q@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_1831700_3	1229909.NSED_02900	1.634e-52	188.0	COG0432@1|root,arCOG04214@2157|Archaea	2157|Archaea	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YYD2_k127_1831700_2	1459636.NTE_02645	1.316e-102	341.0	COG1533@1|root,arCOG01290@2157|Archaea	2157|Archaea	L	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD2_k127_18391_0	1459636.NTE_00041	9.926e-123	403.0	COG0704@1|root,arCOG00318@2157|Archaea,41SC5@651137|Thaumarchaeota	2157|Archaea	K	Phosphate uptake regulator	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
YYD2_k127_1845393_2	289376.THEYE_A0845	3.092e-33	132.0	COG2110@1|root,COG2110@2|Bacteria	2|Bacteria	P	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	Macro
YYD2_k127_1845393_0	1131266.ARWQ01000014_gene82	8.63e-81	276.0	COG0846@1|root,arCOG04248@2157|Archaea,41SWP@651137|Thaumarchaeota	651137|Thaumarchaeota	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
YYD2_k127_1845393_1	1459636.NTE_02660	1.835e-49	181.0	COG0537@1|root,arCOG00419@2157|Archaea,41SNI@651137|Thaumarchaeota	651137|Thaumarchaeota	F	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
YYD2_k127_1852700_0	1459636.NTE_01667	3.545e-32	128.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1858017_0	1459636.NTE_02122	3.864e-48	178.0	COG1744@1|root,arCOG00257@2157|Archaea	2157|Archaea	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
YYD2_k127_1867722_3	1459636.NTE_02057	7.245e-07	51.0	COG2007@1|root,arCOG04154@2157|Archaea,41SP2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein S8e	rps8e	-	-	ko:K02995	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8e
YYD2_k127_1867722_0	1459636.NTE_02061	2.197e-68	236.0	COG1386@1|root,arCOG02613@2157|Archaea,41SIC@651137|Thaumarchaeota	651137|Thaumarchaeota	K	segregation and condensation protein	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
YYD2_k127_1867722_1	1459636.NTE_02062	1.098e-66	234.0	COG1354@1|root,arCOG02610@2157|Archaea,41SMU@651137|Thaumarchaeota	651137|Thaumarchaeota	L	chromosome segregation and condensation protein ScpA	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	-
YYD2_k127_1867722_2	1459636.NTE_02193	1.13e-27	116.0	COG1758@1|root,arCOG01268@2157|Archaea,41ST9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoK	-	-	ko:K03014	ko00230,ko00240,ko01100,ko03020,ko04623,ko05016,ko05169,map00230,map00240,map01100,map03020,map04623,map05016,map05169	M00180,M00181,M00182	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
YYD2_k127_1874720_0	1459636.NTE_01667	8.907e-08	55.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1876992_1	1229909.NSED_08345	1.636e-12	70.0	arCOG04405@1|root,arCOG04405@2157|Archaea	2157|Archaea	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
YYD2_k127_1876992_0	1459636.NTE_01493	1.518e-12	72.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YYD2_k127_1878301_0	1459636.NTE_01626	1.043e-44	167.0	COG3243@1|root,arCOG06344@2157|Archaea,41SEX@651137|Thaumarchaeota	651137|Thaumarchaeota	I	TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
YYD2_k127_1878301_1	1459636.NTE_01627	1.454e-11	72.0	arCOG06343@1|root,arCOG06343@2157|Archaea,41SRX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
YYD2_k127_1878301_2	1459636.NTE_01445	3.074e-07	56.0	arCOG08754@1|root,arCOG08754@2157|Archaea,41SUV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1897369_0	319795.Dgeo_2191	3.044e-12	74.0	2DBFF@1|root,2Z8YA@2|Bacteria	2|Bacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
YYD2_k127_1899092_0	1459636.NTE_01058	1.576e-150	487.0	arCOG04732@1|root,arCOG04732@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1899092_1	1459636.NTE_01048	2.1e-10	63.0	COG0624@1|root,arCOG01110@2157|Archaea,41SAE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YYD2_k127_1901250_0	1041930.Mtc_1149	3.741e-80	280.0	COG0530@1|root,arCOG02881@2157|Archaea,2Y2BH@28890|Euryarchaeota,2NAGG@224756|Methanomicrobia	224756|Methanomicrobia	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
YYD2_k127_1904085_1	1419583.V466_22330	2.026e-07	59.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RZD3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind
YYD2_k127_1904085_0	1441629.PCH70_47820	6.02e-15	85.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1Z902@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	Q	Haemolysin-type calcium binding protein related domain	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	HCBP_related,HemolysinCabind
YYD2_k127_1914396_0	247490.KSU1_D0999	1.055e-18	100.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
YYD2_k127_1929235_2	1459636.NTE_01204	1.838e-53	190.0	COG1358@1|root,arCOG01751@2157|Archaea,41SMS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs	rpl7ae	-	-	ko:K02936	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03009,ko03011	-	-	-	Ribosomal_L7Ae
YYD2_k127_1929235_3	1459636.NTE_01203	2.345e-30	120.0	COG2053@1|root,arCOG04314@2157|Archaea,41ST6@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS28 family	rps28e	-	-	ko:K02979	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S28e
YYD2_k127_1929235_4	1459636.NTE_01202	3.384e-30	120.0	COG2075@1|root,arCOG01950@2157|Archaea,41T7M@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl24e	-	-	ko:K02896	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L24e
YYD2_k127_1929235_1	1459636.NTE_01201	7.594e-57	200.0	COG0105@1|root,arCOG04313@2157|Archaea,41SN1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YYD2_k127_1929235_0	1459636.NTE_01200	1.318e-241	756.0	COG0532@1|root,arCOG01560@2157|Archaea,41SBY@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2	infB	-	-	ko:K03243	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D4,IF-2
YYD2_k127_1941225_7	1459636.NTE_01588	6.871e-23	99.0	COG2151@1|root,arCOG01845@2157|Archaea,41SQV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
YYD2_k127_1941225_2	1459636.NTE_01591	7.372e-114	374.0	COG0479@1|root,arCOG00962@2157|Archaea,41SAW@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
YYD2_k127_1941225_4	1459636.NTE_01592	9.141e-41	154.0	COG2142@1|root,arCOG04162@2157|Archaea,41SRA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
YYD2_k127_1941225_3	1459636.NTE_01593	2.738e-67	233.0	COG2009@1|root,arCOG02244@2157|Archaea,41SKZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
YYD2_k127_1941225_0	1459636.NTE_01594	3.247e-313	965.0	COG1053@1|root,arCOG00571@2157|Archaea,41SAM@651137|Thaumarchaeota	651137|Thaumarchaeota	C	fumarate reductase flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YYD2_k127_1941225_1	1459636.NTE_01603	1.428e-139	455.0	COG0124@1|root,arCOG00404@2157|Archaea,41S9T@651137|Thaumarchaeota	651137|Thaumarchaeota	J	histidyl-tRNA synthetase	-	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YYD2_k127_1941225_5	1459636.NTE_01604	2.926e-26	116.0	COG1371@1|root,arCOG04055@2157|Archaea,41SU0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
YYD2_k127_1941225_8	1459636.NTE_01199	2.151e-11	64.0	COG0526@1|root,arCOG01972@2157|Archaea,41T6S@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YYD2_k127_1962343_1	797209.ZOD2009_13711	1.567e-15	81.0	arCOG00517@1|root,arCOG00517@2157|Archaea,2XSV0@28890|Euryarchaeota,23SNB@183963|Halobacteria	183963|Halobacteria	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
YYD2_k127_1962343_0	118168.MC7420_7123	2.605e-72	250.0	COG0500@1|root,COG2226@2|Bacteria,1G1SP@1117|Cyanobacteria,1H91U@1150|Oscillatoriales	1117|Cyanobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YYD2_k127_1966856_0	1459636.NTE_00331	1.446e-34	134.0	COG0517@1|root,arCOG00607@2157|Archaea	2157|Archaea	M	Belongs to the peptidase M50B family	-	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
YYD2_k127_1966856_1	323261.Noc_0461	7.306e-15	78.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,1X1ZU@135613|Chromatiales	135613|Chromatiales	S	ChaB	-	-	-	ko:K06197	-	-	-	-	ko00000	-	-	-	ChaB
YYD2_k127_1966901_0	1459636.NTE_01968	5.328e-86	294.0	COG0457@1|root,arCOG03032@2157|Archaea,41T0V@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1
YYD2_k127_1971575_1	1459636.NTE_01702	1.45e-62	217.0	COG0379@1|root,arCOG04459@2157|Archaea,41S6Y@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
YYD2_k127_1971575_2	1459636.NTE_01699	6.798e-20	91.0	COG4919@1|root,arCOG04293@2157|Archaea,41SVI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein S30	-	-	-	ko:K02983	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04121	-	-	-	Ribosomal_S30
YYD2_k127_1971575_0	1459636.NTE_01703	2.613e-64	227.0	COG0157@1|root,arCOG01482@2157|Archaea,41SHI@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Involved in the catabolism of quinolinic acid (QA)	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
YYD2_k127_1986728_2	1459636.NTE_03217	0.0001178	46.0	COG1634@1|root,arCOG04303@2157|Archaea,41SKX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP)	mptE	-	2.7.6.3	ko:K07142	ko00790,map00790	-	R03503	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	MAF_flag10
YYD2_k127_1986728_1	1459636.NTE_03219	3.062e-45	171.0	arCOG05463@1|root,arCOG05463@2157|Archaea,41SR3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1986728_0	1459636.NTE_03220	1.12e-194	615.0	COG0519@1|root,arCOG00085@2157|Archaea,41SDI@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
YYD2_k127_199247_1	391613.RTM1035_09848	0.0009538	45.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,46RE2@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_M10_C
YYD2_k127_199247_0	364733.XP_007803399.1	1.785e-06	57.0	KOG1565@1|root,KOG1565@2759|Eukaryota,3A7XK@33154|Opisthokonta,3PQKI@4751|Fungi,3QZRW@4890|Ascomycota,20P6K@147545|Eurotiomycetes	4751|Fungi	OW	Belongs to the peptidase M10A family	-	-	-	ko:K08002	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PG_binding_1,Peptidase_M10
YYD2_k127_2020281_5	1459636.NTE_01052	4.9e-26	110.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_2020281_0	436308.Nmar_0409	1.177e-134	443.0	COG0579@1|root,arCOG00754@2157|Archaea,41SXA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
YYD2_k127_2020281_3	1459636.NTE_02408	2.153e-34	134.0	arCOG08080@1|root,arCOG08080@2157|Archaea,41SUA@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2020281_2	436308.Nmar_1783	3.592e-45	173.0	COG2112@1|root,arCOG01182@2157|Archaea,41SJV@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Ser thr protein kinase	-	-	-	ko:K07176	-	-	-	-	ko00000	-	-	-	RIO1
YYD2_k127_2020281_1	1229909.NSED_09545	1.314e-98	339.0	COG1746@1|root,arCOG04249@2157|Archaea,41S76@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
YYD2_k127_2021915_1	1459636.NTE_02122	1.937e-12	69.0	COG1744@1|root,arCOG00257@2157|Archaea	2157|Archaea	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
YYD2_k127_2021915_0	1459636.NTE_01496	1.473e-65	232.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_2022226_0	237368.SCABRO_02482	6.584e-08	62.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,2J1R4@203682|Planctomycetes	203682|Planctomycetes	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,PAS_9,dCache_1
YYD2_k127_202396_0	1459636.NTE_01478	3.598e-61	221.0	COG0044@1|root,arCOG00689@2157|Archaea,41S8A@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
YYD2_k127_2024750_0	66874.JOFS01000005_gene3957	3.804e-11	74.0	COG4409@1|root,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria	201174|Actinobacteria	G	BNR Asp-box repeat	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Laminin_G_3
YYD2_k127_202652_0	1229909.NSED_05585	8.391e-31	126.0	arCOG00516@1|root,arCOG00516@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyridox_ox_2
YYD2_k127_202652_1	1499967.BAYZ01000148_gene1744	3.675e-17	85.0	2CG94@1|root,337GB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2026892_6	1459636.NTE_01833	6.708e-31	121.0	COG0185@1|root,arCOG04099@2157|Archaea,41SMH@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rps19p	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
YYD2_k127_2026892_3	1459636.NTE_01832	9.328e-73	247.0	COG0091@1|root,arCOG04098@2157|Archaea,41SJ4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rpl22	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
YYD2_k127_2026892_0	1459636.NTE_01831	8.322e-90	304.0	COG0092@1|root,arCOG04097@2157|Archaea,41SIM@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds the lower part of the 30S subunit head	rps3	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YYD2_k127_2026892_9	1459636.NTE_01830	7.198e-19	88.0	COG0255@1|root,arCOG00785@2157|Archaea,41SV8@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uL29 family	rpl29	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
YYD2_k127_2026892_10	573063.Metin_0628	5.059e-10	63.0	COG1588@1|root,arCOG00784@2157|Archaea,2Y0EN@28890|Euryarchaeota,23R70@183939|Methanococci	183939|Methanococci	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp1	GO:0000172,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03538	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	UPF0086
YYD2_k127_2026892_5	1459636.NTE_01828	1.944e-42	157.0	COG0186@1|root,arCOG04096@2157|Archaea,41SSH@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rps17	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
YYD2_k127_2026892_1	1459636.NTE_01827	1.011e-74	252.0	COG0093@1|root,arCOG04095@2157|Archaea,41SHG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rpl14	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
YYD2_k127_2026892_8	1459636.NTE_01826	3.401e-26	113.0	COG0198@1|root,arCOG04094@2157|Archaea,41SSS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located at the polypeptide exit tunnel on the outside of the subunit	rpl24	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L26
YYD2_k127_2026892_2	1459636.NTE_01825	3.315e-73	253.0	COG1471@1|root,arCOG04093@2157|Archaea,41SIE@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS4 family	rps4e	-	-	ko:K02987	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	RS4NT,Ribosomal_S4e,S4
YYD2_k127_2026892_4	1459636.NTE_01824	2.38e-66	230.0	COG0094@1|root,arCOG04092@2157|Archaea,41SJP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rpl5	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
YYD2_k127_2026892_7	1459636.NTE_01823	4.263e-28	113.0	COG0199@1|root,arCOG00782@2157|Archaea,41SW8@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein S14	rps14	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
YYD2_k127_2036923_1	1459636.NTE_01647	2.368e-75	267.0	COG0215@1|root,arCOG00486@2157|Archaea,41SEW@651137|Thaumarchaeota	1459636.NTE_01647|-	J	PFAM tRNA synthetases class I (C) catalytic domain	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	-
YYD2_k127_2036923_2	1459636.NTE_01646	3.462e-12	77.0	COG0454@1|root,arCOG05161@2157|Archaea	2157|Archaea	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2036923_0	1459636.NTE_01644	7.447e-124	411.0	COG1196@1|root,arCOG00371@2157|Archaea,41SDS@651137|Thaumarchaeota	651137|Thaumarchaeota	D	SMC proteins Flexible Hinge Domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YYD2_k127_2053133_1	1459636.NTE_00110	1.397e-110	362.0	COG0209@1|root,arCOG01917@1|root,arCOG03713@1|root,arCOG01917@2157|Archaea,arCOG03713@2157|Archaea,arCOG04276@2157|Archaea,41SAH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
YYD2_k127_2053133_0	1459636.NTE_00009	3.118e-149	477.0	COG0540@1|root,arCOG00911@2157|Archaea,41S6H@651137|Thaumarchaeota	651137|Thaumarchaeota	F	aspartate carbamoyltransferase	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YYD2_k127_2053133_3	436308.Nmar_1428	5.426e-37	146.0	COG1818@1|root,arCOG00084@2157|Archaea,41SNW@651137|Thaumarchaeota	651137|Thaumarchaeota	S	THUMP domain	-	-	-	ko:K06963	-	-	-	-	ko00000,ko03016	-	-	-	THUMP
YYD2_k127_2053133_2	1459636.NTE_02379	4.152e-48	179.0	COG0009@1|root,arCOG01952@2157|Archaea,41SPF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Sua5 YciO YrdC YwlC family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
YYD2_k127_2078931_0	1459636.NTE_02426	8.295e-100	333.0	COG0053@1|root,arCOG01474@2157|Archaea	2157|Archaea	P	cation diffusion facilitator family transporter	cef	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
YYD2_k127_2090265_1	880073.Calab_2707	3.948e-13	75.0	COG3852@1|root,COG4191@1|root,COG5002@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,2NS4C@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YYD2_k127_2090265_0	1459636.NTE_00004	1.808e-14	81.0	COG0468@1|root,arCOG00415@2157|Archaea	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	-	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
YYD2_k127_2091279_0	908338.HMPREF9286_0708	7.48e-46	175.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,22H3B@1570339|Peptoniphilaceae	186801|Clostridia	T	phosphatase 2C	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
YYD2_k127_2093730_0	1459636.NTE_02182	1.145e-22	111.0	arCOG03439@1|root,arCOG03439@2157|Archaea	2157|Archaea	L	PFAM periplasmic copper-binding	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,F5_F8_type_C
YYD2_k127_2098953_1	1459636.NTE_01717	3.259e-68	237.0	arCOG08639@1|root,arCOG08639@2157|Archaea,41SP8@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2098953_0	1459636.NTE_01908	4.264e-160	511.0	COG0468@1|root,arCOG00415@2157|Archaea,41SBA@651137|Thaumarchaeota	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
YYD2_k127_2098953_4	368408.Tpen_0769	5.272e-05	48.0	COG0640@1|root,arCOG03859@2157|Archaea	2157|Archaea	K	ligase activity	-	-	-	ko:K00666,ko:K03892	-	-	-	-	ko00000,ko01000,ko01004,ko03000	-	-	-	HTH_20,HTH_5
YYD2_k127_2098953_2	1459636.NTE_01573	1.342e-20	93.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_2101901_0	935948.KE386494_gene559	5.164e-29	128.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,42F3P@68295|Thermoanaerobacterales	186801|Clostridia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YYD2_k127_2102108_0	1459636.NTE_01675	5.326e-183	584.0	COG1199@1|root,arCOG00770@2157|Archaea,41T2V@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HELICc2	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_2
YYD2_k127_2107406_0	1459636.NTE_03491	1.756e-06	53.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_2115297_0	1459636.NTE_01493	5.964e-50	190.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YYD2_k127_2126343_0	909663.KI867150_gene743	1.289e-12	73.0	COG0745@1|root,COG0745@2|Bacteria,1N3R6@1224|Proteobacteria,42TU3@68525|delta/epsilon subdivisions,2WQ9W@28221|Deltaproteobacteria,2MSJP@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD2_k127_2187515_0	1459636.NTE_03411	4.204e-95	314.0	COG1146@1|root,arCOG04548@2157|Archaea,41SI0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM 4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
YYD2_k127_2194525_1	1459636.NTE_02936	3.05e-74	250.0	COG0100@1|root,arCOG04240@2157|Archaea,41SII@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located on the platform of the 30S subunit	rps11	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YYD2_k127_2194525_3	1459636.NTE_02934	1.538e-30	124.0	arCOG05529@1|root,arCOG05529@2157|Archaea,41SSJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	dsDNA_bind
YYD2_k127_2194525_0	1459636.NTE_02933	7.222e-238	743.0	COG1690@1|root,arCOG04246@2157|Archaea,41SE4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
YYD2_k127_2194525_2	1459636.NTE_03551	2.54e-56	203.0	COG0307@1|root,arCOG04713@2157|Archaea,41SKQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	riboflavin synthase, alpha	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
YYD2_k127_2194525_4	1459636.NTE_03549	2.219e-19	89.0	COG0108@1|root,arCOG01320@2157|Archaea,41SFW@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	-	-	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase
YYD2_k127_2197038_0	1267533.KB906736_gene1024	5.985e-13	74.0	arCOG11428@1|root,33YIA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2199225_1	1459636.NTE_01492	4.88e-25	106.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_2199225_0	1459636.NTE_01052	8.793e-117	401.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_2199225_2	1123355.JHYO01000015_gene1958	1.178e-05	51.0	COG0745@1|root,COG0745@2|Bacteria,1N9SP@1224|Proteobacteria,2U6CP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	cheY-homologous receiver domain	MA20_29080	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD2_k127_220140_0	1094980.Mpsy_0997	3.558e-54	204.0	COG0683@1|root,arCOG01021@2157|Archaea,2Y6Q1@28890|Euryarchaeota,2NAW8@224756|Methanomicrobia	224756|Methanomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YYD2_k127_2206128_0	1459636.NTE_03464	4.565e-44	168.0	COG1752@1|root,arCOG09020@2157|Archaea	2157|Archaea	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
YYD2_k127_2208057_1	1459636.NTE_01052	7.143e-09	62.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_2208057_0	1131266.ARWQ01000024_gene138	2.499e-225	717.0	COG1269@1|root,arCOG04138@2157|Archaea,41SRH@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
YYD2_k127_2208057_2	1121004.ATVC01000001_gene345	6.013e-06	48.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,2KPP5@206351|Neisseriales	206351|Neisseriales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
YYD2_k127_2229849_1	1459636.NTE_02211	8.734e-79	271.0	COG1250@1|root,arCOG00249@2157|Archaea	2157|Archaea	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.116,4.2.1.17	ko:K01715,ko:K15019	ko00650,ko00720,ko01120,ko01200,map00650,map00720,map01120,map01200	M00375	R03026,R03045	RC00831,RC00834	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YYD2_k127_2229849_0	1131266.ARWQ01000028_gene1022	2.55e-226	712.0	COG1866@1|root,arCOG06073@2157|Archaea,41SE5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
YYD2_k127_2229849_2	1459636.NTE_01298	2.395e-69	243.0	COG0500@1|root,arCOG01631@2157|Archaea,41SJC@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	RNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	DOT1
YYD2_k127_2229849_3	1487953.JMKF01000017_gene2547	1.049e-36	142.0	COG0599@1|root,COG0599@2|Bacteria,1G6DQ@1117|Cyanobacteria	1117|Cyanobacteria	S	gamma-carboxymuconolactone decarboxylase subunit	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
YYD2_k127_2235245_0	1122172.KB890260_gene1932	9.53e-15	79.0	COG0745@1|root,COG0745@2|Bacteria,379Q8@32066|Fusobacteria	32066|Fusobacteria	K	Psort location Cytoplasmic, score 9.97	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_2235245_1	1459636.NTE_01962	1.14e-11	70.0	arCOG08680@1|root,arCOG08680@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2235245_2	1209989.TepiRe1_0591	9.285e-11	64.0	COG1926@1|root,COG1926@2|Bacteria,1V256@1239|Firmicutes,249BZ@186801|Clostridia,42GND@68295|Thermoanaerobacterales	186801|Clostridia	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
YYD2_k127_2248950_0	436308.Nmar_1219	5.069e-06	52.0	COG0582@1|root,arCOG01241@2157|Archaea	2157|Archaea	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	ssrA	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
YYD2_k127_2249892_0	857293.CAAU_0579	5.215e-13	74.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,36ERD@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Gram_pos_anchor,LysM,Metallophos
YYD2_k127_2262240_0	591019.Shell_0124	1.214e-14	79.0	arCOG12413@1|root,arCOG12413@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2266040_2	4787.PITG_01181T0	1.036e-11	70.0	COG0526@1|root,KOG2699@1|root,KOG0907@2759|Eukaryota,KOG2699@2759|Eukaryota,3QBRY@4776|Peronosporales	4776|Peronosporales	O	PUB domain	-	-	-	-	-	-	-	-	-	-	-	-	PUB,Thioredoxin,UBA
YYD2_k127_2266040_1	1459636.NTE_03499	2.612e-81	279.0	COG5486@1|root,arCOG10678@2157|Archaea	2157|Archaea	S	metal-binding integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
YYD2_k127_2266040_0	1459636.NTE_00752	4.97e-105	346.0	COG5588@1|root,arCOG11393@2157|Archaea	1459636.NTE_00752|-	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2269407_1	1459636.NTE_02233	5.198e-92	307.0	COG0560@1|root,arCOG01158@2157|Archaea,41SHX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	phosphoserine phosphatase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
YYD2_k127_2269407_2	1459636.NTE_02235	4.074e-75	259.0	COG1478@1|root,arCOG02714@2157|Archaea,41T27@651137|Thaumarchaeota	651137|Thaumarchaeota	H	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
YYD2_k127_2269407_3	1459636.NTE_02237	3.235e-30	121.0	COG0425@1|root,arCOG02062@2157|Archaea,41SU5@651137|Thaumarchaeota	651137|Thaumarchaeota	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	TusA
YYD2_k127_2269407_0	1459636.NTE_02238	8.547e-152	483.0	COG0031@1|root,arCOG01430@2157|Archaea,41SYM@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Cysteine synthase	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD2_k127_2269512_0	1459636.NTE_00763	2.901e-68	241.0	COG0596@1|root,arCOG07416@1|root,arCOG01648@2157|Archaea,arCOG07416@2157|Archaea,41SFU@651137|Thaumarchaeota	2157|Archaea	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
YYD2_k127_2270600_1	1216362.B437_03926	1.165e-06	58.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YYD2_k127_2279228_0	1459636.NTE_01496	5.161e-54	206.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_2279228_1	1528106.JRJE01000004_gene663	3.124e-14	85.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2TZSN@28211|Alphaproteobacteria,2JTSY@204441|Rhodospirillales	204441|Rhodospirillales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,PAS_9
YYD2_k127_228461_0	399550.Smar_1370	2.909e-118	394.0	COG0017@1|root,arCOG00407@2157|Archaea,2XQ0M@28889|Crenarchaeota	28889|Crenarchaeota	J	PFAM tRNA synthetase, class II (D, K and N)	-	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YYD2_k127_2290024_0	1459636.NTE_02430	5.527e-39	160.0	COG1651@1|root,arCOG02868@2157|Archaea,41T2W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YYD2_k127_2301661_0	1056495.Calag_1008	8.519e-73	252.0	COG1573@1|root,arCOG00905@2157|Archaea,2XRWR@28889|Crenarchaeota	28889|Crenarchaeota	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YYD2_k127_2303190_0	195250.CM001776_gene961	6.974e-34	147.0	COG0358@1|root,COG0358@2|Bacteria	2|Bacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_N,zf-CHC2
YYD2_k127_2315378_0	1459636.NTE_03453	3.038e-68	241.0	COG0596@1|root,arCOG07416@1|root,arCOG01648@2157|Archaea,arCOG07416@2157|Archaea	2157|Archaea	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
YYD2_k127_2323732_0	2325.TKV_c18590	1.537e-25	120.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,42F3P@68295|Thermoanaerobacterales	186801|Clostridia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YYD2_k127_2323732_1	436308.Nmar_1518	1.124e-20	94.0	arCOG04405@1|root,arCOG04405@2157|Archaea	2157|Archaea	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
YYD2_k127_2357330_2	1459636.NTE_03274	2.409e-158	524.0	COG1269@1|root,arCOG04138@2157|Archaea,41SRH@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
YYD2_k127_2357330_8	1459636.NTE_01532	2.405e-22	99.0	arCOG08750@1|root,arCOG08750@2157|Archaea	1459636.NTE_01532|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2357330_4	1459636.NTE_02858	1.259e-68	239.0	COG0149@1|root,arCOG01087@2157|Archaea,41SHT@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
YYD2_k127_2357330_0	1459636.NTE_02857	9.058e-205	641.0	COG1980@1|root,arCOG04180@2157|Archaea,41S67@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P)	fbp	-	3.1.3.11,4.1.2.13	ko:K01622	ko00010,ko00030,ko00051,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00003	R00762,R01068,R01070,R02568,R04780	RC00017,RC00438,RC00439	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_3
YYD2_k127_2357330_1	1459636.NTE_00103	9.166e-175	571.0	COG0550@1|root,arCOG01527@2157|Archaea,41TBA@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	-
YYD2_k127_2357330_3	436308.Nmar_1633	3.504e-90	304.0	COG0388@1|root,arCOG00062@2157|Archaea,41SF8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
YYD2_k127_2357330_7	1459636.NTE_01386	1.431e-26	112.0	COG0350@1|root,arCOG02724@2157|Archaea,41SR8@651137|Thaumarchaeota	651137|Thaumarchaeota	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
YYD2_k127_2357330_5	1459636.NTE_02742	3.731e-60	227.0	COG0672@1|root,arCOG04330@2157|Archaea,41T07@651137|Thaumarchaeota	651137|Thaumarchaeota	P	High-affinity Fe2 Pb2 permease	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
YYD2_k127_2374105_3	1459636.NTE_00579	3.944e-17	81.0	COG0663@1|root,arCOG01849@2157|Archaea	2157|Archaea	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	ko:K08698	-	-	-	-	ko00000	-	-	-	Hexapep
YYD2_k127_2374105_1	1459636.NTE_00579	1.696e-47	172.0	COG0663@1|root,arCOG01849@2157|Archaea	2157|Archaea	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	ko:K08698	-	-	-	-	ko00000	-	-	-	Hexapep
YYD2_k127_2374105_0	1459636.NTE_01493	6.066e-52	198.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YYD2_k127_2374105_2	1459636.NTE_01491	5.918e-26	111.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2377174_0	1459636.NTE_01998	2.184e-67	233.0	COG0778@1|root,arCOG00288@2157|Archaea	2157|Archaea	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YYD2_k127_2378884_0	526218.Sterm_0340	5.157e-06	58.0	COG0790@1|root,COG0790@2|Bacteria,37CFE@32066|Fusobacteria	32066|Fusobacteria	S	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_2,TPR_8
YYD2_k127_2379568_0	1220534.B655_2320	1.509e-59	216.0	COG2239@1|root,arCOG00625@2157|Archaea,2XSUY@28890|Euryarchaeota	28890|Euryarchaeota	P	transporter (mgtE)	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
YYD2_k127_2379568_1	1459636.NTE_01500	7.169e-16	78.0	COG0281@1|root,arCOG00853@2157|Archaea	2157|Archaea	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
YYD2_k127_2380100_1	330214.NIDE1052	2.343e-26	113.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
YYD2_k127_2385142_0	63737.Npun_R1990	2.682e-131	424.0	COG0596@1|root,COG0596@2|Bacteria,1G0CB@1117|Cyanobacteria	1117|Cyanobacteria	S	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD2_k127_2385142_1	436308.Nmar_1695	1.648e-36	141.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
YYD2_k127_2388057_1	1229909.NSED_01780	1.591e-05	47.0	COG1525@1|root,arCOG03192@2157|Archaea	2157|Archaea	L	COG1525 Micrococcal nuclease (thermonuclease) homologs	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
YYD2_k127_2388057_0	1459636.NTE_00005	1.205e-11	72.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2388057_2	574376.BAMA_00935	3.487e-05	47.0	COG2133@1|root,COG2133@2|Bacteria,1VBUK@1239|Firmicutes,4HKNP@91061|Bacilli	91061|Bacilli	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
YYD2_k127_2388110_2	1229909.NSED_01780	1.591e-05	47.0	COG1525@1|root,arCOG03192@2157|Archaea	2157|Archaea	L	COG1525 Micrococcal nuclease (thermonuclease) homologs	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
YYD2_k127_2388110_1	56780.SYN_00331	3.625e-08	54.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
YYD2_k127_2388110_0	234267.Acid_0536	1.752e-09	59.0	COG2818@1|root,COG2818@2|Bacteria,3Y4NC@57723|Acidobacteria	57723|Acidobacteria	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
YYD2_k127_2398456_0	696747.NIES39_D04320	2.251e-16	88.0	COG2931@1|root,COG2931@2|Bacteria,1G1I0@1117|Cyanobacteria,1H84J@1150|Oscillatoriales	1117|Cyanobacteria	Q	RTX toxins and related Ca2 binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HemolysinCabind
YYD2_k127_2399374_2	1459636.NTE_01764	1.313e-73	251.0	COG1676@1|root,arCOG01701@2157|Archaea,41SHW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	tRNA intron endonuclease, N-terminal domain	-	-	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
YYD2_k127_2399374_4	1459636.NTE_01763	8.24e-41	158.0	COG1392@1|root,arCOG02640@2157|Archaea,41SGI@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
YYD2_k127_2399374_1	1459636.NTE_01853	2.232e-153	491.0	COG0460@1|root,arCOG01351@2157|Archaea,41SAC@651137|Thaumarchaeota	651137|Thaumarchaeota	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
YYD2_k127_2399374_3	1459636.NTE_01851	8.451e-56	203.0	COG0730@1|root,arCOG02050@2157|Archaea,41SKY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YYD2_k127_2399374_0	1459636.NTE_01087	0.0	1053.0	COG1032@1|root,arCOG01357@2157|Archaea,41SCX@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD2_k127_2399374_5	1459636.NTE_02437	2.606e-22	96.0	COG1552@1|root,arCOG04049@2157|Archaea,41T87@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL40 family	-	-	-	ko:K02927	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	-
YYD2_k127_2399374_6	1229909.NSED_06465	1.445e-15	81.0	arCOG03008@1|root,arCOG03008@2157|Archaea,41STF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD2_k127_2399607_0	70601.3257244	1.836e-70	259.0	COG0467@1|root,arCOG01174@2157|Archaea,2XV95@28890|Euryarchaeota,243WZ@183968|Thermococci	183968|Thermococci	T	Pfam:KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
YYD2_k127_2401763_0	1459636.NTE_01088	1.925e-18	88.0	arCOG08763@1|root,arCOG08763@2157|Archaea,41SWC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2404007_2	1459636.NTE_02757	1.652e-58	209.0	COG0533@1|root,arCOG01185@2157|Archaea,41SJJ@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Mn2 -dependent serine threonine protein kinase	-	-	2.7.11.1	ko:K08851	-	-	-	-	ko00000,ko01000,ko01001,ko03016	-	-	-	Pkinase
YYD2_k127_2404007_3	1459636.NTE_02758	7.981e-31	124.0	arCOG10590@1|root,arCOG10590@2157|Archaea,41SSG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2404007_1	1459636.NTE_02759	2.163e-136	441.0	COG0533@1|root,arCOG01183@2157|Archaea,41SDX@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37	kae1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YYD2_k127_2404007_0	1459636.NTE_02760	5.67e-169	540.0	COG0012@1|root,arCOG00357@2157|Archaea,41S71@651137|Thaumarchaeota	651137|Thaumarchaeota	J	GTPase of unknown function C-terminal	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
YYD2_k127_2404007_4	1459636.NTE_02328	6.167e-12	70.0	COG0034@1|root,arCOG00093@2157|Archaea,41S7N@651137|Thaumarchaeota	2157|Archaea	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
YYD2_k127_2404007_5	1463926.JOCA01000015_gene319	5.907e-05	49.0	COG1208@1|root,COG1208@2|Bacteria,2GMX6@201174|Actinobacteria	201174|Actinobacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
YYD2_k127_2406021_0	1459636.NTE_03061	1.763e-96	322.0	COG0842@1|root,arCOG01467@2157|Archaea,41SQQ@651137|Thaumarchaeota	651137|Thaumarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
YYD2_k127_2406147_0	1459636.NTE_03481	7.054e-93	321.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
YYD2_k127_2406520_0	1459636.NTE_03470	2.325e-21	100.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD2_k127_2406520_1	1459636.NTE_02515	7.72e-21	98.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
YYD2_k127_2416277_0	348780.NP_1046A	6.341e-20	98.0	arCOG03919@1|root,arCOG03919@2157|Archaea,2XUDK@28890|Euryarchaeota,23TJR@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NicO
YYD2_k127_2423690_1	1459636.NTE_01914	4.645e-69	244.0	COG0134@1|root,arCOG01088@2157|Archaea,41SN7@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Indole-3-glycerol phosphate synthase	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
YYD2_k127_2423690_0	436308.Nmar_0657	1.28e-96	327.0	COG1262@1|root,arCOG03517@2157|Archaea,41T1B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
YYD2_k127_2435306_0	693979.Bache_1820	6.731e-16	84.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,4NGRD@976|Bacteroidetes,2FM1D@200643|Bacteroidia,4APMD@815|Bacteroidaceae	976|Bacteroidetes	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
YYD2_k127_2456562_1	1459636.NTE_02846	4.36e-15	79.0	arCOG07573@1|root,arCOG07573@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2456562_2	102125.Xen7305DRAFT_00046300	0.000127	51.0	COG4276@1|root,COG4276@2|Bacteria,1G60I@1117|Cyanobacteria,3VJVN@52604|Pleurocapsales	1117|Cyanobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
YYD2_k127_2461027_1	443254.Marpi_0823	2.27e-37	154.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
YYD2_k127_2461027_0	1295642.H839_02156	5.179e-113	372.0	COG2141@1|root,COG2141@2|Bacteria,1TT4S@1239|Firmicutes,4HBJB@91061|Bacilli,1WEVF@129337|Geobacillus	91061|Bacilli	C	Luciferase-like monooxygenase	luxA_2	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
YYD2_k127_2461120_2	1459636.NTE_01414	9.071e-18	86.0	COG3269@1|root,arCOG01641@2157|Archaea	2157|Archaea	J	RNA-binding protein contains TRAM domain	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
YYD2_k127_2461120_0	1459636.NTE_01413	3.569e-132	430.0	COG0371@1|root,arCOG00982@2157|Archaea,41T0B@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
YYD2_k127_2461120_1	1459636.NTE_02621	4.122e-60	216.0	COG1047@1|root,arCOG00980@2157|Archaea,41T0T@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
YYD2_k127_2463264_0	1459636.NTE_01398	5.524e-64	227.0	arCOG08728@1|root,arCOG08728@2157|Archaea,41SW1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2463264_1	1459636.NTE_01667	7.303e-31	124.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2463264_2	1229909.NSED_08180	0.0001477	46.0	COG1522@1|root,arCOG01117@2157|Archaea,41ST7@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
YYD2_k127_2463451_0	886379.AEWI01000042_gene3355	1.385e-44	173.0	COG0438@1|root,COG0438@2|Bacteria,4PHQK@976|Bacteroidetes,2G1M2@200643|Bacteroidia,3XJWK@558415|Marinilabiliaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YYD2_k127_2463451_1	439481.Aboo_0238	4.939e-21	96.0	arCOG06939@1|root,arCOG06939@2157|Archaea,2XWTJ@28890|Euryarchaeota	28890|Euryarchaeota	S	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
YYD2_k127_2463708_0	1459636.NTE_01035	2.547e-118	389.0	COG0640@1|root,COG1809@1|root,arCOG00394@2157|Archaea,arCOG04896@2157|Archaea	2157|Archaea	K	PFAM (2R)-phospho-3-sulfolactate synthase ComA	comA	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
YYD2_k127_2463708_1	1459636.NTE_03130	1.29e-09	59.0	COG0600@1|root,arCOG00169@2157|Archaea,41SIT@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
YYD2_k127_2464619_0	261292.Nit79A3_1409	4.052e-34	134.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
YYD2_k127_2470970_0	1459636.NTE_00636	1.569e-96	324.0	COG0524@1|root,arCOG00014@2157|Archaea,41SX4@651137|Thaumarchaeota	651137|Thaumarchaeota	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YYD2_k127_2470970_1	1459636.NTE_00635	8.27e-80	271.0	COG0163@1|root,arCOG01703@2157|Archaea,41SHU@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
YYD2_k127_2470970_2	1459636.NTE_00633	3.594e-57	205.0	COG1094@1|root,arCOG04150@2157|Archaea,41SNG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	K homology RNA-binding domain	-	-	-	ko:K06961	-	-	-	-	ko00000,ko03009	-	-	-	KH_1
YYD2_k127_2471402_1	1459636.NTE_00035	2.833e-51	188.0	COG1846@1|root,arCOG03748@2157|Archaea,41T7R@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2471402_0	1459636.NTE_00950	1.626e-178	564.0	COG1180@1|root,arCOG00946@2157|Archaea,41SBZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
YYD2_k127_2473998_0	706587.Desti_2409	3.678e-60	213.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,2MQWH@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
YYD2_k127_2473998_1	436308.Nmar_1695	1.947e-19	88.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
YYD2_k127_2476360_0	572546.Arcpr_1622	1.627e-30	124.0	COG0780@1|root,arCOG02435@1|root,arCOG02435@2157|Archaea,arCOG04210@2157|Archaea,2Y5QB@28890|Euryarchaeota	28890|Euryarchaeota	F	PFAM GTP cyclohydrolase I	-	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
YYD2_k127_2482574_0	933262.AXAM01000164_gene2940	6.675e-22	110.0	COG0438@1|root,COG0438@2|Bacteria,1N1RZ@1224|Proteobacteria,42UHY@68525|delta/epsilon subdivisions,2WQD7@28221|Deltaproteobacteria,2MKYI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_2484784_2	1459636.NTE_02995	1.864e-08	59.0	COG0582@1|root,arCOG01245@2157|Archaea,41T6H@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YYD2_k127_2484784_1	1459636.NTE_01963	2.097e-88	300.0	COG0648@1|root,arCOG01894@2157|Archaea,41SDW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
YYD2_k127_2484784_0	1459636.NTE_00981	3.078e-137	442.0	COG0423@1|root,arCOG00405@2157|Archaea,41S8S@651137|Thaumarchaeota	651137|Thaumarchaeota	J	synthetase (class II)	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
YYD2_k127_2485885_0	1459636.NTE_01922	1.69e-64	230.0	COG0524@1|root,arCOG00016@2157|Archaea,41SJA@651137|Thaumarchaeota	651137|Thaumarchaeota	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YYD2_k127_2486899_7	1459636.NTE_01532	5.424e-22	98.0	arCOG08750@1|root,arCOG08750@2157|Archaea	1459636.NTE_01532|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2486899_3	1459636.NTE_00799	2.287e-96	322.0	COG2107@1|root,arCOG00654@2157|Archaea,41SB8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
YYD2_k127_2486899_1	1459636.NTE_00789	1.001e-174	554.0	COG1060@1|root,arCOG00656@2157|Archaea,41SEG@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
YYD2_k127_2486899_2	1459636.NTE_00788	6.198e-167	531.0	COG1060@1|root,arCOG00656@2157|Archaea,41SCN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD2_k127_2486899_0	1459636.NTE_01316	8.15e-241	751.0	COG3425@1|root,arCOG01767@2157|Archaea,41SAQ@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Hydroxymethylglutaryl-coenzyme A synthase N terminal	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
YYD2_k127_2486899_4	1229909.NSED_09230	6.28e-38	147.0	COG5615@1|root,arCOG05392@2157|Archaea,41T4B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
YYD2_k127_2486899_5	1459636.NTE_02714	7.722e-26	113.0	arCOG03788@1|root,arCOG03788@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
YYD2_k127_2486899_6	1131266.ARWQ01000005_gene797	2.233e-23	104.0	COG1522@1|root,arCOG04153@2157|Archaea,41SP6@651137|Thaumarchaeota	651137|Thaumarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2486899_10	1313421.JHBV01000003_gene619	0.0001454	46.0	COG3485@1|root,COG3485@2|Bacteria,4NN13@976|Bacteroidetes,1IZE6@117747|Sphingobacteriia	976|Bacteroidetes	Q	Dioxygenase	-	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C
YYD2_k127_2486899_9	1121946.AUAX01000012_gene6716	3.161e-07	54.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria,4D9IZ@85008|Micromonosporales	201174|Actinobacteria	Q	Dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
YYD2_k127_248762_1	436308.Nmar_0079	5.203e-47	174.0	COG1797@1|root,arCOG00106@2157|Archaea,41SBP@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
YYD2_k127_248762_0	1131266.ARWQ01000002_gene678	4.123e-87	299.0	COG1063@1|root,arCOG01459@2157|Archaea,41S98@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_2498352_1	1459636.NTE_03114	5.932e-68	241.0	COG0079@1|root,arCOG04273@2157|Archaea,41SGU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM Aminotransferase class I and II	-	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
YYD2_k127_2498352_0	1459636.NTE_03115	2.746e-87	295.0	COG1492@1|root,arCOG00105@2157|Archaea,41SG6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA
YYD2_k127_2499610_5	221288.JH992901_gene458	5.135e-05	49.0	2E4G4@1|root,32ZB9@2|Bacteria,1G9UK@1117|Cyanobacteria,1JMIU@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2499610_2	485913.Krac_4214	8.521e-86	297.0	COG3227@1|root,COG3227@2|Bacteria,2G6Q0@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M4 thermolysin	-	-	3.4.24.27	ko:K08603	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	FTP,PLN_propep,Peptidase_M4,Peptidase_M4_C
YYD2_k127_2499610_1	1122622.ATWJ01000007_gene1747	4.532e-86	313.0	COG4249@1|root,COG4249@2|Bacteria,2IAM3@201174|Actinobacteria,4FFYH@85021|Intrasporangiaceae	201174|Actinobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
YYD2_k127_2499610_4	1337936.IJ00_16100	5.895e-10	73.0	COG1357@1|root,COG1357@2|Bacteria,1G8T3@1117|Cyanobacteria,1HKQH@1161|Nostocales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
YYD2_k127_2499610_3	1255043.TVNIR_1740	3.219e-56	222.0	COG0457@1|root,COG0457@2|Bacteria,1R1XZ@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
YYD2_k127_2499610_0	1255043.TVNIR_1740	9.559e-117	386.0	COG0457@1|root,COG0457@2|Bacteria,1R1XZ@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
YYD2_k127_2506551_0	234267.Acid_0434	1.052e-06	57.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	choD	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,FAD_oxidored,GMC_oxred_C,GMC_oxred_N
YYD2_k127_2512365_1	5147.XP_003342390.1	3.852e-12	65.0	COG0843@1|root,KOG4769@2759|Eukaryota,38JQ7@33154|Opisthokonta,3NYGG@4751|Fungi,3QSKE@4890|Ascomycota	4751|Fungi	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	cox1	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1
YYD2_k127_2512365_0	31870.EFQ24846	1.689e-15	75.0	COG0843@1|root,KOG4769@2759|Eukaryota,38JQ7@33154|Opisthokonta,3NYGG@4751|Fungi,3QSKE@4890|Ascomycota,21STW@147550|Sordariomycetes,1F541@1028384|Glomerellales	4751|Fungi	Q	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	cox1	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1
YYD2_k127_2512365_2	5147.XP_003342390.1	1.301e-10	61.0	COG0843@1|root,KOG4769@2759|Eukaryota,38JQ7@33154|Opisthokonta,3NYGG@4751|Fungi,3QSKE@4890|Ascomycota	4751|Fungi	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	cox1	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1
YYD2_k127_2515380_3	643867.Ftrac_3235	9.38e-05	52.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,47PA6@768503|Cytophagia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
YYD2_k127_2515380_0	1300345.LF41_2983	4.571e-62	227.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,Cellulase,NHL,RicinB_lectin_2
YYD2_k127_2515380_2	883.DvMF_2867	6.93e-13	77.0	COG3926@1|root,COG3926@2|Bacteria,1Q91V@1224|Proteobacteria,43A7H@68525|delta/epsilon subdivisions,2WUT0@28221|Deltaproteobacteria,2MBA6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted Peptidoglycan domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_3
YYD2_k127_2515380_1	406817.XNC1_2197	3.337e-18	89.0	COG0494@1|root,COG0494@2|Bacteria,1N9TV@1224|Proteobacteria,1SG85@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD2_k127_2522376_0	1459636.NTE_01233	6.679e-243	766.0	COG0674@1|root,arCOG01606@2157|Archaea,41S60@651137|Thaumarchaeota	651137|Thaumarchaeota	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
YYD2_k127_2525634_1	1459636.NTE_01573	1.15e-16	82.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_2532740_0	1459636.NTE_01927	1.485e-110	376.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1,sCache_3_3
YYD2_k127_2532740_1	1459636.NTE_01494	1.375e-24	106.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01494|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_253681_0	1459636.NTE_03523	7.399e-08	59.0	COG3391@1|root,arCOG08716@1|root,arCOG02562@2157|Archaea,arCOG08716@2157|Archaea	2157|Archaea	Q	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,PKD
YYD2_k127_2542350_0	1229909.NSED_04350	4.085e-10	68.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_2547618_1	1041930.Mtc_2322	2.011e-14	75.0	COG0531@1|root,arCOG00009@2157|Archaea,2Y01P@28890|Euryarchaeota,2NB7R@224756|Methanomicrobia	224756|Methanomicrobia	E	amino acid	-	-	-	ko:K16263	-	-	-	-	ko00000,ko02000	2.A.3.13	-	-	AA_permease_2
YYD2_k127_2547618_0	243232.MJ_0653	1.118e-22	103.0	COG0517@1|root,arCOG00606@2157|Archaea,2XX11@28890|Euryarchaeota,23QUR@183939|Methanococci	183939|Methanococci	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YYD2_k127_2557109_0	1459636.NTE_03452	1.109e-60	212.0	COG1146@1|root,arCOG04548@2157|Archaea,41SI0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM 4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
YYD2_k127_2559010_3	1385512.N784_05285	4.459e-24	107.0	COG0458@1|root,COG0458@2|Bacteria,1UIGF@1239|Firmicutes,4IUCV@91061|Bacilli	91061|Bacilli	EF	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
YYD2_k127_2559010_0	1459636.NTE_02402	1.49e-87	305.0	COG1215@1|root,arCOG01389@2157|Archaea,41TAH@651137|Thaumarchaeota	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.212	ko:K00752	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	Glycos_transf_2
YYD2_k127_2559010_1	1459636.NTE_00033	5.153e-82	279.0	COG1121@1|root,arCOG00201@2157|Archaea,41S7E@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
YYD2_k127_2559010_2	1459636.NTE_00034	1.368e-32	129.0	COG1108@1|root,arCOG01006@2157|Archaea,41SG2@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
YYD2_k127_2567399_0	5888.CAK66192	3.167e-68	245.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
YYD2_k127_2567399_1	1459636.NTE_01513	1.682e-12	68.0	arCOG10403@1|root,arCOG10403@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2571729_0	1174528.JH992893_gene5996	7.582e-88	300.0	COG0596@1|root,COG0596@2|Bacteria,1G6JI@1117|Cyanobacteria,1JMVF@1189|Stigonemataceae	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD2_k127_2571729_1	1028800.RG540_CH39100	2.393e-23	100.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2U16Z@28211|Alphaproteobacteria,4BDVS@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
YYD2_k127_2590878_1	1459636.NTE_01650	2.431e-39	148.0	COG1581@1|root,arCOG01753@2157|Archaea	2157|Archaea	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
YYD2_k127_2590878_2	1229909.NSED_03315	1.327e-15	79.0	arCOG08668@1|root,arCOG08668@2157|Archaea,41SW4@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2590878_0	1459636.NTE_01677	2.187e-79	278.0	COG0389@1|root,arCOG04582@2157|Archaea,41SDV@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis	dbh	-	2.7.7.7	ko:K04479	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
YYD2_k127_2592926_1	1131451.O1K_18178	1.467e-08	61.0	COG3293@1|root,COG3293@2|Bacteria,1REUV@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
YYD2_k127_2592926_0	621372.ACIH01000178_gene3647	5.071e-29	119.0	COG3293@1|root,COG3293@2|Bacteria,1U545@1239|Firmicutes,4I1B9@91061|Bacilli	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_259921_0	1444711.CCJF01000005_gene196	4.263e-160	535.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2JFD0@204428|Chlamydiae	204428|Chlamydiae	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
YYD2_k127_259921_1	986075.CathTA2_1346	4.205e-49	185.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4HC5V@91061|Bacilli	91061|Bacilli	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
YYD2_k127_2606963_0	485913.Krac_2159	1.492e-179	577.0	COG3511@1|root,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	acpA	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
YYD2_k127_2606963_1	1459636.NTE_00723	3.263e-43	162.0	COG0361@1|root,arCOG01179@2157|Archaea,41SRK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits	-	-	-	ko:K03236	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	eIF-1a
YYD2_k127_2612685_0	1009370.ALO_16856	2.395e-209	681.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H1X5@909932|Negativicutes	909932|Negativicutes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
YYD2_k127_2613672_0	483219.LILAB_32590	3.598e-18	89.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1MX4X@1224|Proteobacteria,43C05@68525|delta/epsilon subdivisions,2X7AX@28221|Deltaproteobacteria,2YWKH@29|Myxococcales	28221|Deltaproteobacteria	N	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
YYD2_k127_2617182_2	1459636.NTE_00080	7.73e-110	360.0	COG1646@1|root,arCOG01085@2157|Archaea,41SH4@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
YYD2_k127_2617182_0	1459636.NTE_00079	0.0	1467.0	COG1933@1|root,arCOG04447@2157|Archaea,41SYW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	PolC_DP2
YYD2_k127_2617182_1	1459636.NTE_03553	5.513e-228	712.0	COG0112@1|root,arCOG00070@2157|Archaea,41S7U@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
YYD2_k127_2617409_0	1459636.NTE_02946	2.311e-127	421.0	COG1109@1|root,arCOG00767@2157|Archaea,41SC1@651137|Thaumarchaeota	651137|Thaumarchaeota	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YYD2_k127_2617409_2	1459636.NTE_03347	2.279e-102	355.0	COG3372@1|root,arCOG04356@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF790)	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
YYD2_k127_2617409_1	1459636.NTE_00766	5.019e-112	370.0	COG0598@1|root,arCOG02265@2157|Archaea,41SZC@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YYD2_k127_2617409_4	1459636.NTE_00456	3.193e-10	64.0	arCOG03142@1|root,arCOG03142@2157|Archaea,41T78@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2635646_1	509635.N824_12955	2.207e-05	51.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,1ITD7@117747|Sphingobacteriia	976|Bacteroidetes	I	Biotin lipoyl attachment domain-containing protein	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
YYD2_k127_2635646_0	1430440.MGMSRv2_0538	2.875e-86	295.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,2JPBR@204441|Rhodospirillales	204441|Rhodospirillales	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YYD2_k127_2651138_0	1459636.NTE_02884	2.204e-117	385.0	COG0829@1|root,arCOG04529@2157|Archaea,41SBH@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
YYD2_k127_2651138_1	1459636.NTE_02885	1.884e-109	357.0	COG0378@1|root,arCOG01231@2157|Archaea,41SAZ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
YYD2_k127_2651138_2	1459636.NTE_02886	1.203e-58	208.0	COG0830@1|root,arCOG04530@2157|Archaea,41SG4@651137|Thaumarchaeota	651137|Thaumarchaeota	O	UreF	-	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
YYD2_k127_265843_1	1459636.NTE_03320	1.422e-36	140.0	COG2146@1|root,arCOG02852@2157|Archaea	2157|Archaea	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	1.7.1.15	ko:K00363,ko:K15762	ko00623,ko00910,ko00920,ko01100,ko01120,ko01220,map00623,map00910,map00920,map01100,map01120,map01220	M00530,M00538	R00787,R02550,R03562,R05666,R09513	RC00176,RC00269,RC00490,RC02556	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
YYD2_k127_265843_0	1459636.NTE_03319	2.54e-165	531.0	COG0215@1|root,arCOG00486@2157|Archaea,41SEW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	PFAM tRNA synthetases class I (C) catalytic domain	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
YYD2_k127_265843_3	1150474.JQJI01000006_gene839	2.673e-14	83.0	COG1388@1|root,COG4733@1|root,COG1388@2|Bacteria,COG4733@2|Bacteria,2GE91@200918|Thermotogae	2|Bacteria	M	Fibronectin type III domain	-	-	-	ko:K03933	-	-	-	-	ko00000	-	AA10,CBM73	-	Bac_DNA_binding,CHAP,fn3
YYD2_k127_265843_2	1459636.NTE_01757	1.141e-31	126.0	COG1890@1|root,arCOG04186@2157|Archaea,41SM9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS1 family	rps3ae	-	-	ko:K02984	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3Ae
YYD2_k127_2663603_0	1459636.NTE_01612	1.299e-119	390.0	COG0258@1|root,arCOG04050@2157|Archaea,41SBU@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
YYD2_k127_2663603_1	679926.Mpet_1264	2.056e-06	53.0	COG3039@1|root,arCOG02751@2157|Archaea,2XTDW@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
YYD2_k127_2667237_0	436308.Nmar_0654	6.367e-74	253.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
YYD2_k127_2669954_0	481448.Minf_0852	5.5e-184	593.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
YYD2_k127_2670836_1	1459636.NTE_03071	1.594e-61	217.0	COG0861@1|root,arCOG09430@2157|Archaea	2157|Archaea	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
YYD2_k127_2670836_0	521011.Mpal_1345	1.558e-66	238.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
YYD2_k127_2671323_0	1459636.NTE_01391	7.4e-108	358.0	COG1234@1|root,arCOG00501@2157|Archaea,41SF7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
YYD2_k127_2671323_2	1459636.NTE_01392	7.068e-81	278.0	COG0462@1|root,arCOG00067@2157|Archaea,41SH1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
YYD2_k127_2671323_1	1459636.NTE_02380	3.857e-85	291.0	COG0145@1|root,arCOG01511@2157|Archaea,41SZ7@651137|Thaumarchaeota	651137|Thaumarchaeota	E	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
YYD2_k127_2673115_4	755178.Cyan10605_1025	0.0006191	46.0	COG0783@1|root,COG0783@2|Bacteria,1G19F@1117|Cyanobacteria	1117|Cyanobacteria	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
YYD2_k127_2673115_1	479434.Sthe_1085	6.494e-23	106.0	arCOG04740@1|root,31PZA@2|Bacteria,2GA0B@200795|Chloroflexi,27Y9E@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2673115_3	526227.Mesil_3459	1.164e-10	64.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	secE2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
YYD2_k127_2673115_2	1094980.Mpsy_1048	4.579e-14	76.0	arCOG04958@1|root,arCOG04958@2157|Archaea,2Y0MG@28890|Euryarchaeota,2N9YS@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2673115_0	1094980.Mpsy_1047	3.975e-62	221.0	COG1842@1|root,arCOG04782@2157|Archaea,2XU11@28890|Euryarchaeota,2N9P1@224756|Methanomicrobia	224756|Methanomicrobia	K	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
YYD2_k127_2689102_0	1459636.NTE_03481	1.149e-100	338.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
YYD2_k127_2695101_0	714943.Mucpa_3919	1.529e-05	52.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1INN4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_2696564_0	436308.Nmar_0654	1.028e-46	169.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
YYD2_k127_2696564_1	693661.Arcve_0574	2.735e-16	87.0	COG3316@1|root,arCOG02134@2157|Archaea,2XUAY@28890|Euryarchaeota	28890|Euryarchaeota	L	COG3316 Transposase and inactivated derivatives	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240,HTH_23
YYD2_k127_2708878_4	1459636.NTE_03327	9.266e-07	59.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2708878_1	1459636.NTE_01729	7.471e-40	153.0	COG1522@1|root,arCOG01585@2157|Archaea,41T4Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal TRASH domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc_trans_TRASH,HTH_AsnC-type
YYD2_k127_2708878_0	697281.Mahau_1243	1.845e-186	607.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,42EQF@68295|Thermoanaerobacterales	186801|Clostridia	P	Heavy metal transport detoxification protein	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
YYD2_k127_2711146_1	1459636.NTE_00970	2.899e-92	307.0	COG2151@1|root,arCOG03838@1|root,arCOG01845@2157|Archaea,arCOG03838@2157|Archaea,41SHR@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P,PqqD
YYD2_k127_2711146_0	1459636.NTE_00981	3.341e-93	310.0	COG0423@1|root,arCOG00405@2157|Archaea,41S8S@651137|Thaumarchaeota	651137|Thaumarchaeota	J	synthetase (class II)	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
YYD2_k127_2714076_0	1459636.NTE_02304	6.661e-38	145.0	COG1581@1|root,arCOG01753@2157|Archaea,41SQ4@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	-	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
YYD2_k127_2714701_0	416591.Tlet_1270	2.866e-15	89.0	COG3947@1|root,COG3947@2|Bacteria	2|Bacteria	T	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HATPase_c,LysM,Response_reg,Trans_reg_C
YYD2_k127_2715151_0	158190.SpiGrapes_0072	0.0002934	48.0	COG0642@1|root,COG0745@1|root,COG0834@1|root,COG2198@1|root,COG0745@2|Bacteria,COG0834@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,2JBGS@203691|Spirochaetes	203691|Spirochaetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,NUDIX,Response_reg,SBP_bac_3
YYD2_k127_2717667_0	1459636.NTE_03282	6.897e-80	271.0	COG0517@1|root,arCOG00606@2157|Archaea	2157|Archaea	I	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YYD2_k127_2717667_1	1459636.NTE_03283	1.506e-36	141.0	COG1293@1|root,arCOG01695@2157|Archaea,41SB0@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
YYD2_k127_271949_1	1459636.NTE_00427	3.655e-22	104.0	arCOG06357@1|root,arCOG06357@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_271949_0	1459636.NTE_01334	3.679e-37	144.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YYD2_k127_2723498_1	1459636.NTE_01122	3.417e-13	69.0	COG0783@1|root,arCOG01101@2157|Archaea	2157|Archaea	P	Belongs to the Dps family	frt	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
YYD2_k127_2723498_0	1459636.NTE_00136	9.962e-53	196.0	COG1938@1|root,arCOG00347@2157|Archaea,41SSA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
YYD2_k127_2728350_0	1459636.NTE_01097	5.924e-117	380.0	COG0473@1|root,arCOG01163@2157|Archaea,41S5U@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YYD2_k127_2728350_3	1459636.NTE_01098	1.102e-61	218.0	arCOG08673@1|root,arCOG08673@2157|Archaea	1459636.NTE_01098|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2728350_1	1459636.NTE_01099	3.593e-116	378.0	COG1409@1|root,arCOG01153@2157|Archaea,41SF2@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YYD2_k127_2728350_5	237368.SCABRO_02434	2.581e-15	81.0	COG0328@1|root,COG0328@2|Bacteria,2J0TM@203682|Planctomycetes	203682|Planctomycetes	L	Reverse transcriptase-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_3
YYD2_k127_2728350_4	1459636.NTE_00620	1.198e-50	185.0	COG0681@1|root,arCOG01739@2157|Archaea,41SQ2@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
YYD2_k127_2728350_2	1459636.NTE_01695	4.359e-71	245.0	COG1163@1|root,arCOG00358@2157|Archaea,41SAD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	small GTP-binding protein	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
YYD2_k127_2730173_0	1459636.NTE_01920	8.847e-237	741.0	COG0504@1|root,arCOG00063@2157|Archaea,41S7G@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
YYD2_k127_2730173_1	1459636.NTE_01921	2.496e-147	474.0	COG0061@1|root,COG0640@1|root,arCOG00394@2157|Archaea,arCOG01348@2157|Archaea,41SEC@651137|Thaumarchaeota	651137|Thaumarchaeota	HK	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
YYD2_k127_2730173_5	1459636.NTE_01923	1.185e-46	169.0	COG4830@1|root,arCOG04305@2157|Archaea,41SNM@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02976	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S26e
YYD2_k127_2730173_4	1131266.ARWQ01000002_gene480	3.815e-50	184.0	COG0558@1|root,arCOG00670@2157|Archaea,41SJ7@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
YYD2_k127_2730173_3	521011.Mpal_0585	1.679e-54	198.0	COG2120@1|root,arCOG03460@2157|Archaea,2XU80@28890|Euryarchaeota,2NAKP@224756|Methanomicrobia	224756|Methanomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YYD2_k127_2730173_2	436308.Nmar_0119	2.021e-57	214.0	COG2244@1|root,arCOG02209@2157|Archaea,41T3C@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2730173_6	1463917.JODC01000007_gene7794	1.216e-09	68.0	COG4409@1|root,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria	201174|Actinobacteria	G	BNR Asp-box repeat	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Laminin_G_3
YYD2_k127_274194_0	1459636.NTE_02652	1.248e-170	543.0	COG0520@1|root,arCOG00065@2157|Archaea,41SCV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YYD2_k127_274194_2	1459636.NTE_02647	3.192e-50	182.0	COG1051@1|root,arCOG01075@2157|Archaea	2157|Archaea	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YYD2_k127_274194_1	1343739.PAP_10195	2.192e-79	273.0	COG0444@1|root,arCOG00181@2157|Archaea,2XSTM@28890|Euryarchaeota,242ZN@183968|Thermococci	183968|Thermococci	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
YYD2_k127_274194_3	1459636.NTE_01666	1.709e-33	133.0	COG0195@1|root,arCOG01761@2157|Archaea,41T4Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2746106_0	1459636.NTE_03160	7.131e-69	243.0	COG0677@1|root,arCOG00252@2157|Archaea	2157|Archaea	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	NAD_binding_2,UDPG_MGDP_dh,UDPG_MGDP_dh_C
YYD2_k127_2746106_1	1459636.NTE_01294	2.311e-49	184.0	COG0586@1|root,arCOG03117@2157|Archaea,41SQ5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YYD2_k127_2747970_0	1459636.NTE_03346	2.564e-159	512.0	COG1061@1|root,arCOG00874@2157|Archaea,41SW0@651137|Thaumarchaeota	2157|Archaea	K	Type III restriction enzyme, res subunit	rad25	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
YYD2_k127_2747970_2	1459636.NTE_02174	1.675e-07	57.0	COG1715@1|root,arCOG02777@2157|Archaea	2157|Archaea	V	restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
YYD2_k127_2747970_1	1459636.NTE_01100	3.781e-115	373.0	arCOG08699@1|root,arCOG08699@2157|Archaea,41S8N@651137|Thaumarchaeota	1459636.NTE_01100|-	C	PFAM Ammonia monooxygenase methane monooxygenase, subunit C	-	-	-	ko:K10946	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002	-	-	-	-
YYD2_k127_2759215_1	1459636.NTE_02333	3.039e-21	98.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2759215_2	309807.SRU_1226	0.0005763	44.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FIS4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_2764453_0	1379698.RBG1_1C00001G0651	3.695e-36	142.0	COG2406@1|root,COG2406@2|Bacteria,2NS0E@2323|unclassified Bacteria	2|Bacteria	S	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
YYD2_k127_2766354_1	1459636.NTE_01725	5.923e-21	93.0	COG1958@1|root,arCOG00998@2157|Archaea,41SS5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	snRNP Sm proteins	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
YYD2_k127_2766354_0	1459636.NTE_01724	4.44e-23	108.0	COG0468@1|root,arCOG00417@2157|Archaea,41SQC@651137|Thaumarchaeota	651137|Thaumarchaeota	T	RecA RadA	-	-	-	ko:K04482,ko:K04483	ko03440,ko03460,ko05200,ko05212,map03440,map03460,map05200,map05212	-	-	-	ko00000,ko00001,ko03400,ko04121,ko04131	-	-	-	Rad51
YYD2_k127_2771432_2	1123511.KB905840_gene805	6.397e-21	98.0	COG2259@1|root,COG2259@2|Bacteria,1VCS2@1239|Firmicutes,4H7ZV@909932|Negativicutes	909932|Negativicutes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
YYD2_k127_2771432_0	1459636.NTE_01054	7.939e-34	132.0	arCOG08023@1|root,arCOG08023@2157|Archaea,41SKK@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
YYD2_k127_2771432_1	227086.JGI_V11_85451	1.156e-22	106.0	COG4122@1|root,KOG1663@2759|Eukaryota	2759|Eukaryota	P	O-methyltransferase activity	comt-1	-	2.1.1.6	ko:K00545	ko00140,ko00350,ko00965,ko01100,ko04728,map00140,map00350,map00965,map01100,map04728	-	R02534,R02920,R03304,R04301,R04762,R04764,R04881,R04887	RC00003,RC00392	ko00000,ko00001,ko01000,ko04147	-	-	-	DUF3752,DnaJ,Methyltransf_24,Methyltransf_3
YYD2_k127_2771996_0	1459636.NTE_01055	3.299e-62	219.0	COG0842@1|root,arCOG01467@2157|Archaea,41SH0@651137|Thaumarchaeota	651137|Thaumarchaeota	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
YYD2_k127_2771996_1	1459636.NTE_01056	6.427e-59	210.0	COG1131@1|root,arCOG00196@2157|Archaea,41S9H@651137|Thaumarchaeota	651137|Thaumarchaeota	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_2777923_0	1459636.NTE_00830	1.68e-13	71.0	COG3324@1|root,arCOG04946@2157|Archaea	2157|Archaea	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
YYD2_k127_278320_0	1459636.NTE_03191	1.166e-172	556.0	arCOG00144@1|root,arCOG00144@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD2_k127_278320_1	1459636.NTE_00560	4.276e-26	110.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2789520_3	395963.Bind_2694	0.0007961	44.0	COG0446@1|root,COG1752@1|root,COG0446@2|Bacteria,COG1752@2|Bacteria,1NR3M@1224|Proteobacteria,2U4PX@28211|Alphaproteobacteria,3NC9J@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Patatin phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3734,Patatin,Pyr_redox_2,Reductase_C
YYD2_k127_2789520_0	189753.AXAS01000051_gene322	1.275e-20	94.0	COG4274@1|root,COG4274@2|Bacteria,1RHJ3@1224|Proteobacteria,2U9XS@28211|Alphaproteobacteria,3JZUN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
YYD2_k127_2789520_1	1459636.NTE_02002	1.015e-15	81.0	arCOG10524@1|root,arCOG10524@2157|Archaea,41SVP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2794305_0	103733.JNYO01000042_gene6052	2.303e-11	76.0	28HYV@1|root,2Z846@2|Bacteria,2ID85@201174|Actinobacteria,4E95Q@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2796555_0	1123288.SOV_5c03890	5.868e-79	271.0	COG1099@1|root,COG1099@2|Bacteria,1UZM4@1239|Firmicutes	1239|Firmicutes	S	PFAM TatD-related deoxyribonuclease	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
YYD2_k127_2800764_0	649747.HMPREF0083_05651	5.759e-48	179.0	29BRG@1|root,2ZYPV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2800764_1	591019.Shell_0124	2.798e-05	48.0	arCOG12413@1|root,arCOG12413@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2803844_0	1459636.NTE_01495	4.414e-144	468.0	COG1653@1|root,arCOG00151@2157|Archaea	2157|Archaea	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
YYD2_k127_2805692_0	395963.Bind_2694	1.056e-09	71.0	COG0446@1|root,COG1752@1|root,COG0446@2|Bacteria,COG1752@2|Bacteria,1NR3M@1224|Proteobacteria,2U4PX@28211|Alphaproteobacteria,3NC9J@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Patatin phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3734,Patatin,Pyr_redox_2,Reductase_C
YYD2_k127_2809405_0	1459636.NTE_00594	8.338e-54	193.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T38@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2809405_1	1459636.NTE_00594	2.27e-45	170.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T38@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2811356_1	1385512.N784_05285	9.971e-31	130.0	COG0458@1|root,COG0458@2|Bacteria,1UIGF@1239|Firmicutes,4IUCV@91061|Bacilli	91061|Bacilli	EF	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
YYD2_k127_2811356_2	1158318.ATXC01000001_gene187	4.06e-15	83.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G3K2@200783|Aquificae	200783|Aquificae	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
YYD2_k127_2811356_0	1459636.NTE_00031	8.45e-45	166.0	COG0864@1|root,arCOG01008@2157|Archaea,41SQM@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Ribbon-helix-helix protein, copG family	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
YYD2_k127_2815227_1	1459636.NTE_01091	2.73e-60	211.0	COG0468@1|root,arCOG00415@2157|Archaea,41SBA@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
YYD2_k127_2815227_4	1459636.NTE_01092	5.762e-35	136.0	COG2139@1|root,arCOG04129@2157|Archaea,41SRF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL21 family	rpl21e	-	-	ko:K02889	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21e
YYD2_k127_2815227_3	1459636.NTE_01093	2.565e-35	137.0	COG1460@1|root,arCOG01016@2157|Archaea,41SQ1@651137|Thaumarchaeota	651137|Thaumarchaeota	K	RNA polymerase Rpb4	-	-	2.7.7.6	ko:K03051	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb4
YYD2_k127_2815227_0	1459636.NTE_01094	1.932e-78	267.0	COG1491@1|root,arCOG04130@2157|Archaea,41SGD@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Protein of unknown function (DUF655)	-	-	-	ko:K07572	-	-	-	-	ko00000	-	-	-	DUF655
YYD2_k127_2815227_2	1459636.NTE_01095	4.492e-54	197.0	COG0030@1|root,arCOG04131@2157|Archaea,41SN0@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	-	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YYD2_k127_2818090_3	243164.DET1448	5.448e-17	80.0	29WVC@1|root,30IH0@2|Bacteria,2G9KW@200795|Chloroflexi,34DPM@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2818090_0	1459636.NTE_01614	8.625e-92	308.0	COG1241@1|root,arCOG00439@2157|Archaea	2157|Archaea	L	Belongs to the MCM family	-	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	MCM,MCM_OB
YYD2_k127_2818090_1	1459636.NTE_01307	1.093e-34	135.0	arCOG10523@1|root,arCOG10523@2157|Archaea,41SSZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2818090_2	436308.Nmar_1432	1.164e-18	87.0	COG2036@1|root,arCOG02144@2157|Archaea,41T91@651137|Thaumarchaeota	651137|Thaumarchaeota	L	transcription factor (CBF NF-Y)	-	-	-	-	-	-	-	-	-	-	-	-	CBFD_NFYB_HMF
YYD2_k127_2818090_5	1459636.NTE_00621	9.333e-14	74.0	arCOG08691@1|root,arCOG08691@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2818368_1	1459636.NTE_00900	9.187e-35	138.0	COG0517@1|root,arCOG00606@2157|Archaea,41T8N@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YYD2_k127_2818368_2	398511.BpOF4_16680	1.525e-11	69.0	COG1359@1|root,COG1359@2|Bacteria,1VH6P@1239|Firmicutes,4HP7D@91061|Bacilli,1ZIWZ@1386|Bacillus	91061|Bacilli	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
YYD2_k127_2818368_0	1459636.NTE_00846	8.324e-45	169.0	COG1994@1|root,COG3582@1|root,arCOG00614@2157|Archaea,arCOG01769@2157|Archaea,41SUB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-AN1
YYD2_k127_2834123_0	1459636.NTE_00795	3.701e-54	194.0	COG1055@1|root,arCOG00238@2157|Archaea,41SXH@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
YYD2_k127_2834123_1	1459636.NTE_03481	8.32e-30	122.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
YYD2_k127_2834555_2	1459636.NTE_00585	9.605e-24	105.0	arCOG07802@1|root,arCOG07802@2157|Archaea	2157|Archaea	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255,F420H2_quin_red
YYD2_k127_2834555_0	1459636.NTE_01226	2.043e-101	331.0	COG2317@1|root,arCOG04247@2157|Archaea	2157|Archaea	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	cxp	GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0050897,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
YYD2_k127_2836986_3	1459636.NTE_02325	1.678e-113	368.0	COG0638@1|root,arCOG00970@2157|Archaea,41T1N@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
YYD2_k127_2836986_2	1131266.ARWQ01000001_gene1220	1.173e-152	495.0	COG0476@1|root,COG1977@1|root,arCOG00536@2157|Archaea,arCOG01676@2157|Archaea,41S5X@651137|Thaumarchaeota	651137|Thaumarchaeota	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF,ThiS
YYD2_k127_2836986_0	1459636.NTE_00076	2.504e-206	647.0	COG0498@1|root,arCOG01434@2157|Archaea,41SEI@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD2_k127_2836986_5	1459636.NTE_00075	2.561e-50	180.0	COG0139@1|root,arCOG02676@2157|Archaea,41SPE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
YYD2_k127_2836986_1	1459636.NTE_00071	1.474e-154	501.0	COG1571@1|root,arCOG01115@2157|Archaea,41S9G@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA	tiaS	-	6.3.4.22	ko:K06932	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1743
YYD2_k127_2836986_4	1459636.NTE_00015	1.673e-78	267.0	COG1976@1|root,arCOG04176@2157|Archaea,41SIP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex	eif6	-	-	ko:K03264	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009,ko03012	-	-	-	eIF-6
YYD2_k127_2842410_0	1459636.NTE_02426	1.768e-98	329.0	COG0053@1|root,arCOG01474@2157|Archaea	2157|Archaea	P	cation diffusion facilitator family transporter	cef	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
YYD2_k127_2845688_0	1459636.NTE_01334	1.318e-55	198.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YYD2_k127_2849576_1	1459636.NTE_02786	1.951e-29	117.0	COG4275@1|root,arCOG10427@2157|Archaea	2157|Archaea	S	Chromate resistance	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
YYD2_k127_2849576_0	1459636.NTE_00025	2.296e-90	308.0	arCOG07536@1|root,arCOG07536@2157|Archaea,41SZB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
YYD2_k127_2856272_1	595460.RRSWK_01036	1.466e-35	141.0	COG2896@1|root,COG2896@2|Bacteria,2IXWS@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
YYD2_k127_2856272_4	313596.RB2501_14949	5.78e-07	54.0	COG1977@1|root,COG1977@2|Bacteria,4NUVK@976|Bacteroidetes,1I5DM@117743|Flavobacteriia	976|Bacteroidetes	H	ThiS family	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
YYD2_k127_2856272_2	1210884.HG799462_gene8173	1.088e-27	117.0	COG0314@1|root,COG0314@2|Bacteria,2IZSA@203682|Planctomycetes	203682|Planctomycetes	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
YYD2_k127_2856272_0	1379698.RBG1_1C00001G0911	2.595e-96	324.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,2NPNE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	2.8.1.12,4.6.1.17	ko:K03635,ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395,R11372	RC02507,RC03425	ko00000,ko00001,ko01000	-	-	-	MOSC,MoCF_biosynth,MoaC
YYD2_k127_2856272_3	1379698.RBG1_1C00001G0910	2.363e-16	83.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YYD2_k127_2859420_0	1459636.NTE_00881	6.824e-29	121.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD2_k127_2859420_1	1459636.NTE_00881	8.409e-26	112.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD2_k127_2859420_2	1459636.NTE_00881	9.001e-21	100.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD2_k127_2861159_0	1459636.NTE_01508	1.333e-08	61.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2870552_3	1459636.NTE_03231	2.358e-05	49.0	arCOG08782@1|root,arCOG08782@2157|Archaea,41SVH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2870552_1	1459636.NTE_02732	7.954e-133	432.0	COG0472@1|root,arCOG03199@2157|Archaea,41S8B@651137|Thaumarchaeota	651137|Thaumarchaeota	M	glycosyl transferase family	-	-	2.7.8.15	ko:K01001	ko00510,ko01100,map00510,map01100	M00055	R05969	RC00002	ko00000,ko00001,ko00002,ko01000,ko01003	-	-	-	Glycos_transf_4
YYD2_k127_2870552_0	1459636.NTE_02733	3.242e-247	784.0	COG1204@1|root,arCOG00553@2157|Archaea,41SAK@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks	hel308	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HHH_5,Helicase_C
YYD2_k127_2876522_1	926569.ANT_21950	0.0003521	45.0	COG2062@1|root,COG2062@2|Bacteria,2G9HZ@200795|Chloroflexi	200795|Chloroflexi	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
YYD2_k127_2876522_0	1459636.NTE_02436	1.514e-71	259.0	arCOG02527@1|root,arCOG02527@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NosD
YYD2_k127_2889221_0	55601.VANGNB10_cII0505c	0.000812	51.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
YYD2_k127_2924233_13	1459636.NTE_01557	7.865e-05	48.0	COG2038@1|root,arCOG04272@2157|Archaea,41SD3@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the UPF0284 family	-	-	-	-	-	-	-	-	-	-	-	-	DBI_PRT
YYD2_k127_2924233_3	1459636.NTE_01556	9.35e-85	285.0	arCOG00517@1|root,arCOG00517@2157|Archaea,41SHJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD2_k127_2924233_6	1459636.NTE_01555	3.505e-69	242.0	COG0063@1|root,arCOG00018@2157|Archaea,41SHM@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX	nnrE	-	5.1.99.6	ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	YjeF_N
YYD2_k127_2924233_9	1459636.NTE_02634	1.192e-47	176.0	COG1591@1|root,arCOG00919@2157|Archaea,41SQP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products	-	-	-	-	-	-	-	-	-	-	-	-	Hjc
YYD2_k127_2924233_8	1459636.NTE_02633	3.996e-53	194.0	COG2178@1|root,arCOG04318@2157|Archaea,41SKR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translin family	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	Translin
YYD2_k127_2924233_0	1459636.NTE_01631	0.0	1102.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,41S7I@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K18594	ko00720,ko01120,map00720,map01120	-	R03157	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
YYD2_k127_2924233_7	1459636.NTE_02622	2.688e-57	200.0	COG0316@1|root,arCOG04560@2157|Archaea,41SKH@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Iron-sulfur cluster assembly accessory protein	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
YYD2_k127_2924233_1	1459636.NTE_02631	1.674e-216	677.0	COG0334@1|root,arCOG01352@2157|Archaea,41S7T@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YYD2_k127_2924233_12	1459636.NTE_02632	3.57e-17	86.0	COG1826@1|root,arCOG02694@2157|Archaea,41SRR@651137|Thaumarchaeota	651137|Thaumarchaeota	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
YYD2_k127_2924233_2	1459636.NTE_01634	6.474e-171	548.0	COG0358@1|root,arCOG04281@2157|Archaea,41S75@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA primase	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4
YYD2_k127_2924233_4	1459636.NTE_01635	1.527e-81	277.0	COG1339@1|root,arCOG01904@2157|Archaea,41SG9@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Domain of unknown function DUF120	-	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase
YYD2_k127_2924233_5	1459636.NTE_01636	8.783e-74	254.0	COG0615@1|root,arCOG03924@1|root,arCOG01222@2157|Archaea,arCOG03924@2157|Archaea,41SPR@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Cytidylyltransferase-like	-	-	2.7.7.2,2.7.7.39	ko:K00980,ko:K14656	ko00564,ko00740,ko01100,ko01110,map00564,map00740,map01100,map01110	-	R00161,R00856	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
YYD2_k127_2924233_10	1459636.NTE_02686	9.992e-25	105.0	arCOG08817@1|root,arCOG08817@2157|Archaea,41SV5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2924233_11	1433287.X808_140	2.903e-18	91.0	COG1522@1|root,COG1522@2|Bacteria,1MWPX@1224|Proteobacteria,1RRPA@1236|Gammaproteobacteria,1Y78B@135625|Pasteurellales	135625|Pasteurellales	K	regulatory protein AsnC	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_AsnC-type
YYD2_k127_2926250_4	1459636.NTE_01695	1.005e-40	154.0	COG1163@1|root,arCOG00358@2157|Archaea,41SAD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	small GTP-binding protein	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
YYD2_k127_2926250_2	1459636.NTE_01695	2.852e-63	219.0	COG1163@1|root,arCOG00358@2157|Archaea,41SAD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	small GTP-binding protein	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
YYD2_k127_2926250_3	1459636.NTE_01257	2.987e-46	169.0	arCOG04033@1|root,arCOG04033@2157|Archaea,41SM5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2926250_5	1459636.NTE_01257	3.825e-11	64.0	arCOG04033@1|root,arCOG04033@2157|Archaea,41SM5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2926250_1	1459636.NTE_01256	4.462e-86	292.0	COG1478@1|root,arCOG02714@2157|Archaea,41SHA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	F420-0:Gamma-glutamyl ligase	-	-	-	-	-	-	-	-	-	-	-	-	F420_ligase
YYD2_k127_2926250_0	1459636.NTE_01255	1.989e-201	631.0	COG0065@1|root,arCOG01698@2157|Archaea,41S7A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
YYD2_k127_2935912_1	443144.GM21_2393	6.683e-27	117.0	2E3IT@1|root,32YH8@2|Bacteria,1N8T8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2954835_1	1459636.NTE_01922	1.012e-07	56.0	COG0524@1|root,arCOG00016@2157|Archaea,41SJA@651137|Thaumarchaeota	651137|Thaumarchaeota	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
YYD2_k127_2954835_0	1229909.NSED_06370	4.146e-24	106.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41SQT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
YYD2_k127_2954835_2	1499680.CCFE01000010_gene145	8.068e-05	48.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,1ZAPN@1386|Bacillus	91061|Bacilli	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	yeaB	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
YYD2_k127_2988032_0	436308.Nmar_0204	3.4e-31	128.0	arCOG10529@1|root,arCOG10529@2157|Archaea,41SSF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3006493_0	1459636.NTE_01644	3.199e-72	261.0	COG1196@1|root,arCOG00371@2157|Archaea,41SDS@651137|Thaumarchaeota	651137|Thaumarchaeota	D	SMC proteins Flexible Hinge Domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YYD2_k127_3007401_0	378806.STAUR_7823	1.977e-40	162.0	2EYGB@1|root,33RQ8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3007401_2	378806.STAUR_4005	0.0005679	45.0	2EYGB@1|root,33RQ8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3010069_0	316274.Haur_2846	7.368e-103	345.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,37738@32061|Chloroflexia	200795|Chloroflexi	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
YYD2_k127_3010069_3	153948.NAL212_1710	8.087e-62	220.0	COG1121@1|root,COG1121@2|Bacteria,1MW47@1224|Proteobacteria,2VNES@28216|Betaproteobacteria,372B0@32003|Nitrosomonadales	28216|Betaproteobacteria	P	AAA domain, putative AbiEii toxin, Type IV TA system	znuC	-	-	ko:K02074,ko:K09817,ko:K11607,ko:K11710	ko02010,map02010	M00242,M00244,M00317,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5,3.A.1.15.7,3.A.1.15.9	-	-	ABC_tran
YYD2_k127_3010069_2	1131553.JIBI01000009_gene1208	1.059e-72	255.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,2VK89@28216|Betaproteobacteria,372S3@32003|Nitrosomonadales	28216|Betaproteobacteria	P	ABC 3 transport family	mntB	-	-	ko:K02075,ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
YYD2_k127_3010069_1	1459636.NTE_02897	1.897e-100	334.0	COG1475@1|root,arCOG11113@2157|Archaea,41SYF@651137|Thaumarchaeota	651137|Thaumarchaeota	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YYD2_k127_3013743_0	1459636.NTE_00142	4.335e-63	224.0	COG1926@1|root,arCOG06847@2157|Archaea	2157|Archaea	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
YYD2_k127_3026804_4	1459636.NTE_01347	4.668e-39	149.0	COG1382@1|root,arCOG01342@2157|Archaea,41SPD@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdB	-	-	ko:K04798	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin_2
YYD2_k127_3026804_5	1459636.NTE_01345	1.264e-31	124.0	COG1997@1|root,arCOG04208@2157|Archaea,41SUE@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal L37ae protein family	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
YYD2_k127_3026804_1	1459636.NTE_01344	6.794e-117	381.0	COG2123@1|root,arCOG01574@2157|Archaea,41SFZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site	rrp42	-	-	ko:K12589	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
YYD2_k127_3026804_0	1459636.NTE_01343	8.725e-127	409.0	COG0689@1|root,arCOG01575@2157|Archaea,41S81@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails	rrp41	-	-	ko:K11600	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
YYD2_k127_3026804_2	1459636.NTE_01342	1.353e-107	354.0	COG1097@1|root,arCOG00678@2157|Archaea,41SHV@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome	rrp4	-	-	ko:K03679	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	KH_1
YYD2_k127_3026804_3	1459636.NTE_01339	7.748e-48	174.0	COG1500@1|root,arCOG04187@2157|Archaea,41SC7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Shwachman-Bodian-Diamond syndrome (SBDS) protein	-	-	-	ko:K14574	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	SBDS,SBDS_C
YYD2_k127_3030305_0	573063.Metin_0662	1.255e-09	63.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota,23R54@183939|Methanococci	183939|Methanococci	S	SMART Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
YYD2_k127_3032708_0	1459636.NTE_02875	1.254e-51	190.0	COG0637@1|root,arCOG02293@2157|Archaea	2157|Archaea	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.18,5.4.2.6	ko:K01091,ko:K01838,ko:K07025	ko00500,ko00630,ko01100,ko01110,ko01130,map00500,map00630,map01100,map01110,map01130	-	R01334,R02728,R11310	RC00017,RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
YYD2_k127_3082926_0	1459636.NTE_00618	4.697e-103	336.0	COG2101@1|root,arCOG01764@2157|Archaea,41SZD@651137|Thaumarchaeota	651137|Thaumarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	-	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
YYD2_k127_3082926_2	1459636.NTE_00615	3.084e-46	173.0	COG0461@1|root,arCOG00029@2157|Archaea,41SJU@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YYD2_k127_3082926_1	1459636.NTE_00614	4.887e-54	203.0	COG3875@1|root,arCOG02046@2157|Archaea,41SK4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3087819_0	1459636.NTE_00139	1.622e-50	190.0	COG0438@1|root,arCOG04796@2157|Archaea,41T9D@651137|Thaumarchaeota	2157|Archaea	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YYD2_k127_3091999_6	1459636.NTE_02275	5.296e-35	136.0	arCOG06055@1|root,arCOG06055@2157|Archaea,41SQ3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3091999_0	1459636.NTE_02276	1.314e-321	987.0	COG1032@1|root,arCOG01357@2157|Archaea,41S86@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD2_k127_3091999_5	1459636.NTE_02277	1.405e-47	174.0	COG0494@1|root,arCOG01078@2157|Archaea	2157|Archaea	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	apa	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
YYD2_k127_3091999_4	1459636.NTE_02283	4.365e-55	201.0	COG0533@1|root,arCOG01185@2157|Archaea	1459636.NTE_02283|-	F	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3091999_3	1459636.NTE_02284	5.721e-63	217.0	arCOG08652@1|root,arCOG08652@2157|Archaea,41SMZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3091999_2	1459636.NTE_02285	2.856e-84	290.0	COG1340@1|root,arCOG01159@2157|Archaea	2157|Archaea	D	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
YYD2_k127_3091999_1	1459636.NTE_01749	1.984e-140	456.0	COG1819@1|root,arCOG01393@2157|Archaea,41SZK@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3097689_1	1996.JOFO01000005_gene166	1.316e-28	118.0	COG3467@1|root,COG3467@2|Bacteria,2IFRI@201174|Actinobacteria,4EQZ6@85012|Streptosporangiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
YYD2_k127_3097689_0	1131266.ARWQ01000004_gene1476	3.917e-78	271.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YYD2_k127_3100357_0	436308.Nmar_0188	2.756e-10	68.0	COG4276@1|root,arCOG04604@2157|Archaea,41SI9@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
YYD2_k127_3122840_1	1459636.NTE_00107	1.218e-09	61.0	arCOG08792@1|root,arCOG08792@2157|Archaea,41SUG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3122840_0	1459636.NTE_01973	2.999e-86	294.0	COG1575@1|root,arCOG00480@2157|Archaea,41S8H@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiA prenyltransferase	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
YYD2_k127_312355_0	1459636.NTE_01477	7.597e-35	137.0	COG1970@1|root,arCOG05213@2157|Archaea	2157|Archaea	M	Large-conductance mechanosensitive channel, MscL	-	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
YYD2_k127_3124936_1	1459636.NTE_03130	1.433e-57	205.0	COG0600@1|root,arCOG00169@2157|Archaea,41SIT@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
YYD2_k127_3124936_0	1094508.Tsac_1663	2.237e-69	243.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
YYD2_k127_3129789_0	436308.Nmar_1695	1.716e-121	398.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
YYD2_k127_3130713_0	1459636.NTE_00160	1.215e-119	406.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea	2157|Archaea	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1,sCache_3_3
YYD2_k127_3130713_2	868131.MSWAN_1574	9.873e-25	109.0	COG1439@1|root,arCOG00721@2157|Archaea,2XWH2@28890|Euryarchaeota,23P50@183925|Methanobacteria	183925|Methanobacteria	V	PIN domain of ribonuclease	-	-	-	ko:K07060	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN_6
YYD2_k127_3130713_1	1459636.NTE_01351	7.411e-77	265.0	COG0061@1|root,arCOG01348@2157|Archaea,41SHP@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
YYD2_k127_3132274_1	1459636.NTE_02920	1.421e-103	349.0	COG1236@1|root,arCOG00545@2157|Archaea,41SYB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	-
YYD2_k127_3132274_0	1459636.NTE_02919	2.587e-164	518.0	COG2141@1|root,arCOG02410@2157|Archaea,41SBM@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Luciferase-like monooxygenase	-	-	-	ko:K14728	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
YYD2_k127_3133238_0	375286.mma_0345	9.509e-61	216.0	COG4977@1|root,COG4977@2|Bacteria,1QUTN@1224|Proteobacteria	1224|Proteobacteria	K	ThiJ PfpI	inhA	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
YYD2_k127_3139297_0	1459636.NTE_01965	2.364e-98	334.0	COG1467@1|root,arCOG04110@2157|Archaea,41SCB@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priS	-	-	ko:K02683	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_S
YYD2_k127_3148834_0	1459636.NTE_02332	1.071e-24	117.0	arCOG10526@1|root,arCOG10526@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_314952_0	1459636.NTE_03261	4.014e-97	327.0	COG1230@1|root,arCOG01477@2157|Archaea	2157|Archaea	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
YYD2_k127_3150289_0	1459636.NTE_02502	5.881e-177	561.0	COG1060@1|root,arCOG00656@2157|Archaea,41SDT@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.77	ko:K11781	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
YYD2_k127_3158640_0	1459636.NTE_02077	1.395e-42	157.0	COG0426@1|root,arCOG00509@2157|Archaea	2157|Archaea	C	flavodoxin nitric oxide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD2_k127_3158959_0	1459636.NTE_02332	1.447e-25	116.0	arCOG10526@1|root,arCOG10526@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_315901_3	436308.Nmar_0307	2.729e-13	74.0	COG1698@1|root,arCOG04308@2157|Archaea,41SRP@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0147 family	-	-	-	ko:K09721	-	-	-	-	ko00000	-	-	-	UPF0147
YYD2_k127_315901_0	1459636.NTE_02012	0.0	1017.0	COG1782@1|root,arCOG00543@2157|Archaea,41T05@651137|Thaumarchaeota	2157|Archaea	S	RNA-metabolising metallo-beta-lactamase	epf2	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_2,KH_7,Lactamase_B,Lactamase_B_6,RMMBL
YYD2_k127_315901_1	1459636.NTE_02003	1.965e-60	217.0	COG0750@1|root,arCOG04064@2157|Archaea,41SW5@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
YYD2_k127_3159525_0	592015.HMPREF1705_00495	6.708e-102	338.0	COG0428@1|root,COG0428@2|Bacteria,3T9UW@508458|Synergistetes	508458|Synergistetes	P	PFAM zinc iron permease	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
YYD2_k127_3159525_1	546271.Selsp_0508	6.313e-15	78.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes	909932|Negativicutes	I	glutaconyl-CoA decarboxylase subunit gamma	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
YYD2_k127_3162216_0	1459636.NTE_01328	1.955e-52	188.0	COG0778@1|root,arCOG00288@2157|Archaea,41T1J@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YYD2_k127_3170338_0	247490.KSU1_C1274	1.736e-25	114.0	COG1409@1|root,COG3534@1|root,COG1409@2|Bacteria,COG3534@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
YYD2_k127_3177352_0	1229909.NSED_08245	9.358e-11	66.0	arCOG08677@1|root,arCOG08677@2157|Archaea,41SVJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3189632_0	1459636.NTE_01081	1.067e-186	595.0	COG1389@1|root,arCOG01165@2157|Archaea,41SJ2@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
YYD2_k127_3189632_1	1459636.NTE_01080	2.358e-120	390.0	COG1697@1|root,arCOG04143@2157|Archaea,41SQF@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
YYD2_k127_3202164_2	1459636.NTE_01641	1.651e-38	147.0	arCOG03119@1|root,arCOG03119@2157|Archaea,41SMJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YYD2_k127_3202164_0	1459636.NTE_01640	2.904e-207	654.0	COG0008@1|root,arCOG00402@2157|Archaea,41SFI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
YYD2_k127_3202164_3	1459636.NTE_01639	3.23e-33	131.0	arCOG07440@1|root,arCOG07440@2157|Archaea,41STP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3202164_1	1459636.NTE_02503	1.158e-38	151.0	COG1060@1|root,arCOG00657@2157|Archaea,41S95@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.77	ko:K11780	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
YYD2_k127_3208194_2	1459636.NTE_03295	3.669e-08	55.0	COG0455@1|root,arCOG00589@2157|Archaea	2157|Archaea	D	COG0455 ATPases involved in chromosome partitioning	-	-	-	ko:K03496,ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
YYD2_k127_3208194_0	1459636.NTE_03296	2.097e-80	287.0	COG0467@1|root,arCOG01171@2157|Archaea	2157|Archaea	T	Circadian clock protein KaiC	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATPase,Arf,Robl_LC7,zf-FCS
YYD2_k127_3208194_1	1459636.NTE_01491	5.334e-17	88.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3208194_3	1121405.dsmv_1693	1.152e-07	61.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,2MMB5@213118|Desulfobacterales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
YYD2_k127_3208830_0	1459636.NTE_02959	1.749e-51	188.0	COG2095@1|root,arCOG01997@2157|Archaea	2157|Archaea	U	UPF0056 membrane protein	snatA	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
YYD2_k127_3208830_1	1459636.NTE_01458	5.537e-29	119.0	arCOG10549@1|root,arCOG10549@2157|Archaea	1459636.NTE_01458|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3208830_2	1229909.NSED_08345	0.000215	44.0	arCOG04405@1|root,arCOG04405@2157|Archaea	2157|Archaea	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
YYD2_k127_3212498_0	913865.DOT_2970	6.025e-08	58.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes	1239|Firmicutes	T	response regulator, receiver	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
YYD2_k127_3216410_0	1094980.Mpsy_2277	1.824e-64	229.0	COG2333@1|root,arCOG03009@2157|Archaea,2XSXI@28890|Euryarchaeota,2NA82@224756|Methanomicrobia	224756|Methanomicrobia	P	Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	LTD,Lactamase_B
YYD2_k127_3229007_4	1459636.NTE_02226	2.795e-21	94.0	COG0099@1|root,arCOG01722@2157|Archaea,41SIW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YYD2_k127_3229007_3	1459636.NTE_02225	6.854e-61	214.0	COG0522@1|root,arCOG04239@2157|Archaea,41SN3@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S4
YYD2_k127_3229007_1	1459636.NTE_02224	3.249e-112	371.0	COG0640@1|root,arCOG03420@1|root,arCOG01687@2157|Archaea,arCOG03420@2157|Archaea	2157|Archaea	K	PFAM S-layer	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,S_layer_C
YYD2_k127_3229007_0	1459636.NTE_02223	8.109e-226	713.0	COG0449@1|root,arCOG00057@2157|Archaea,41SFG@651137|Thaumarchaeota	651137|Thaumarchaeota	M	TIGRFAM glucosamine--fructose-6-phosphate aminotransferase (isomerizing)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YYD2_k127_3229007_2	1459636.NTE_01557	1.604e-109	365.0	COG2038@1|root,arCOG04272@2157|Archaea,41SD3@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the UPF0284 family	-	-	-	-	-	-	-	-	-	-	-	-	DBI_PRT
YYD2_k127_3265867_1	1459636.NTE_03024	4.875e-20	91.0	COG1430@1|root,arCOG03116@2157|Archaea	2157|Archaea	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
YYD2_k127_3265867_0	930945.SiRe_0134	3.388e-97	329.0	COG0604@1|root,arCOG01458@2157|Archaea,2XPW5@28889|Crenarchaeota	28889|Crenarchaeota	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_329578_1	649639.Bcell_1839	7.074e-13	76.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1TQXC@1239|Firmicutes,4HCSG@91061|Bacilli,1ZD8Q@1386|Bacillus	91061|Bacilli	K	MerR family transcriptional regulator	ycgE	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
YYD2_k127_329578_0	701176.VIBRN418_08532	8.128e-20	96.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XWTA@135623|Vibrionales	135623|Vibrionales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
YYD2_k127_3306946_1	1459636.NTE_02558	1.09e-98	323.0	COG0377@1|root,arCOG01554@2157|Archaea,41S6D@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the complex I 20 kDa subunit family	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YYD2_k127_3306946_2	1459636.NTE_02559	2.312e-60	212.0	COG0838@1|root,arCOG01557@2157|Archaea,41SMI@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YYD2_k127_3306946_0	1459636.NTE_02579	8.888e-165	526.0	COG0644@1|root,arCOG00570@2157|Archaea,41S82@651137|Thaumarchaeota	651137|Thaumarchaeota	C	geranylgeranyl reductase	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_oxidored,Trp_halogenase
YYD2_k127_3306946_3	1459636.NTE_02586	7.372e-50	182.0	COG1225@1|root,arCOG00310@2157|Archaea,41SN5@651137|Thaumarchaeota	651137|Thaumarchaeota	O	AhpC/TSA antioxidant enzyme	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YYD2_k127_330887_2	1459636.NTE_02171	1.703e-59	215.0	COG1407@1|root,arCOG01150@2157|Archaea,41SJB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Calcineurin-like phosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos
YYD2_k127_330887_0	1459636.NTE_02172	0.0	1457.0	COG0458@1|root,arCOG01594@2157|Archaea,41SBF@651137|Thaumarchaeota	651137|Thaumarchaeota	E	MGS-like domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YYD2_k127_330887_7	436308.Nmar_1085	0.0008989	42.0	COG0458@1|root,arCOG01594@2157|Archaea,41SBF@651137|Thaumarchaeota	651137|Thaumarchaeota	E	MGS-like domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YYD2_k127_330887_1	1459636.NTE_02173	4.163e-164	524.0	COG0505@1|root,arCOG00064@2157|Archaea,41SF0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
YYD2_k127_330887_6	1051646.VITU9109_15628	1.1e-06	61.0	COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1XT0T@135623|Vibrionales	135623|Vibrionales	G	COG3325 Chitinase	chiA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ
YYD2_k127_330887_4	410359.Pcal_0484	3.441e-17	93.0	COG1215@1|root,arCOG01389@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011,ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
YYD2_k127_330887_3	1459636.NTE_00770	2.28e-57	203.0	COG0231@1|root,arCOG04277@2157|Archaea,41SNP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Functions by promoting the formation of the first peptide bond	eif5a	-	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	eIF-5a
YYD2_k127_3310108_0	1459636.NTE_00866	7.262e-64	225.0	COG1392@1|root,arCOG02640@2157|Archaea,41SKJ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
YYD2_k127_3310108_1	1459636.NTE_00865	1.619e-62	218.0	COG0306@1|root,arCOG02267@2157|Archaea,41SD8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
YYD2_k127_3340886_1	1459636.NTE_02656	2.317e-11	67.0	arCOG08761@1|root,arCOG08761@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3340886_0	1459636.NTE_02655	1.641e-48	181.0	COG0671@1|root,arCOG03056@2157|Archaea,41SQ8@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
YYD2_k127_3340886_2	1459636.NTE_00341	1.611e-09	61.0	COG2801@1|root,arCOG02125@2157|Archaea	2157|Archaea	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,rve
YYD2_k127_3342880_1	1459636.NTE_00871	1.667e-56	208.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD2_k127_3342880_2	1459636.NTE_02333	5.432e-14	78.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3342880_0	1459636.NTE_02630	4.184e-65	225.0	COG1522@1|root,arCOG01580@2157|Archaea,41T4E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
YYD2_k127_334445_0	1346330.M472_03095	2.197e-12	68.0	COG3809@1|root,COG3809@2|Bacteria,4NWSY@976|Bacteroidetes,1IUHP@117747|Sphingobacteriia	976|Bacteroidetes	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
YYD2_k127_33473_1	360107.CHAB381_1476	4.018e-10	67.0	COG5017@1|root,COG5017@2|Bacteria,1PVGP@1224|Proteobacteria,431BJ@68525|delta/epsilon subdivisions,2YS6J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	D-glucuronyl C5-epimerase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	C5-epim_C
YYD2_k127_3378744_0	700598.Niako_7074	8.132e-30	120.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IPJW@117747|Sphingobacteriia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
YYD2_k127_3398807_1	1313421.JHBV01000155_gene784	2.424e-09	66.0	28MC2@1|root,2ZAQD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3398807_0	521011.Mpal_1345	1.393e-43	164.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
YYD2_k127_34064_2	1459636.NTE_00401	1.272e-16	81.0	COG1794@1|root,arCOG02005@2157|Archaea,41SM4@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
YYD2_k127_34064_1	1131266.ARWQ01000005_gene849	1.977e-28	120.0	COG0454@1|root,arCOG00826@2157|Archaea,41T2E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.4	ko:K00621	ko00520,map00520	-	R02058	RC00004,RC00166	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
YYD2_k127_34064_0	1459636.NTE_02295	3.982e-90	304.0	COG2897@1|root,arCOG02019@2157|Archaea,41SXR@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
YYD2_k127_341163_2	1459636.NTE_01534	1.347e-48	188.0	COG0389@1|root,COG1801@1|root,arCOG04291@2157|Archaea,arCOG04582@2157|Archaea,41SDV@651137|Thaumarchaeota	2157|Archaea	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis	dbh	-	2.7.7.7	ko:K04479	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
YYD2_k127_341163_0	1459636.NTE_01534	1.818e-68	241.0	COG0389@1|root,COG1801@1|root,arCOG04291@2157|Archaea,arCOG04582@2157|Archaea,41SDV@651137|Thaumarchaeota	2157|Archaea	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis	dbh	-	2.7.7.7	ko:K04479	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
YYD2_k127_341768_1	1459636.NTE_01334	3.529e-26	109.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YYD2_k127_341768_0	436308.Nmar_0978	1.538e-50	190.0	COG5012@1|root,arCOG03402@2157|Archaea	2157|Archaea	T	Cobalamin B12-binding domain protein	-	-	-	ko:K16955,ko:K22491	ko00920,map00920	-	R09997	RC00035	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2
YYD2_k127_3420821_0	472759.Nhal_0843	5.122e-52	194.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,1RNMT@1236|Gammaproteobacteria,1WXIM@135613|Chromatiales	135613|Chromatiales	P	PFAM Ion transport	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
YYD2_k127_342566_0	1459636.NTE_03025	5.719e-95	324.0	COG0060@1|root,arCOG00807@2157|Archaea,41SFF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
YYD2_k127_3427724_1	1459636.NTE_01843	6.673e-93	312.0	COG0152@1|root,arCOG04421@2157|Archaea,41SAR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
YYD2_k127_3427724_3	1459636.NTE_01841	2.177e-42	159.0	COG2090@1|root,arCOG04171@2157|Archaea,41SNF@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF371)	-	-	-	ko:K09738	-	-	-	-	ko00000	-	-	-	DUF371
YYD2_k127_3427724_0	1459636.NTE_01839	1.747e-116	379.0	COG0638@1|root,arCOG00971@2157|Archaea,41SYA@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Proteasome endopeptidase complex	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
YYD2_k127_3427724_2	1459636.NTE_01838	6.874e-54	192.0	arCOG08717@1|root,arCOG08717@2157|Archaea,41SFQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD2_k127_342931_0	1041930.Mtc_2322	7.781e-63	230.0	COG0531@1|root,arCOG00009@2157|Archaea,2Y01P@28890|Euryarchaeota,2NB7R@224756|Methanomicrobia	224756|Methanomicrobia	E	amino acid	-	-	-	ko:K16263	-	-	-	-	ko00000,ko02000	2.A.3.13	-	-	AA_permease_2
YYD2_k127_3444302_1	1459636.NTE_00426	6.624e-18	85.0	arCOG08809@1|root,arCOG08809@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_345915_2	1122915.AUGY01000020_gene6450	4.506e-27	121.0	COG1082@1|root,COG1082@2|Bacteria,1TRXP@1239|Firmicutes,4HC31@91061|Bacilli,26Z0E@186822|Paenibacillaceae	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD2_k127_345915_0	1459636.NTE_00729	1.677e-63	228.0	COG5012@1|root,arCOG03932@1|root,arCOG03402@2157|Archaea,arCOG03932@2157|Archaea,41SKB@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Cobalamin B12-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_345915_1	1459636.NTE_00731	1.687e-42	157.0	COG0137@1|root,arCOG00112@2157|Archaea,41S6K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
YYD2_k127_351477_0	1137281.D778_00458	3.07e-13	80.0	COG1345@1|root,COG1361@1|root,COG3227@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3227@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
YYD2_k127_3515076_1	1459636.NTE_03208	2.732e-41	153.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
YYD2_k127_3515076_0	1459636.NTE_03051	4.412e-127	409.0	COG0090@1|root,arCOG04067@2157|Archaea,41SCT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rpl2	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YYD2_k127_3515076_2	1459636.NTE_01293	2.872e-19	87.0	COG0448@1|root,arCOG00912@2157|Archaea,41SEY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YYD2_k127_352781_0	1459636.NTE_02300	4.941e-27	116.0	arCOG08690@1|root,arCOG08690@2157|Archaea,41T98@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_353176_1	1459636.NTE_02122	3.59e-13	71.0	COG1744@1|root,arCOG00257@2157|Archaea	2157|Archaea	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
YYD2_k127_353176_0	1459636.NTE_01496	2.048e-99	338.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_3536010_0	1459636.NTE_03539	3.967e-101	335.0	COG1012@1|root,arCOG01252@2157|Archaea,41T12@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
YYD2_k127_3538441_2	1459636.NTE_01492	5.773e-20	100.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_3538441_1	1459636.NTE_01125	1.754e-28	116.0	arCOG13015@1|root,arCOG13015@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
YYD2_k127_3538441_0	1304885.AUEY01000025_gene2740	2.644e-51	190.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,1PMC1@1224|Proteobacteria,430UF@68525|delta/epsilon subdivisions,2WVWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
YYD2_k127_3538441_3	75379.Tint_1117	0.0001133	44.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,1KJC5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
YYD2_k127_3542298_0	1131266.ARWQ01000001_gene1117	2.554e-71	244.0	COG1048@1|root,arCOG01697@2157|Archaea,41SE6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YYD2_k127_356744_0	251221.35212624	2.647e-61	214.0	COG3961@1|root,COG3961@2|Bacteria,1G1A5@1117|Cyanobacteria	1117|Cyanobacteria	C	Belongs to the TPP enzyme family	pdc	-	4.1.1.74	ko:K04103	ko00380,ko01100,map00380,map01100	-	R01974	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YYD2_k127_3607133_0	1459636.NTE_03260	1.238e-08	63.0	arCOG10517@1|root,arCOG10517@2157|Archaea,41T0I@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3625758_1	1459636.NTE_01697	1.998e-10	61.0	COG3269@1|root,arCOG01641@2157|Archaea	2157|Archaea	J	RNA-binding protein contains TRAM domain	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
YYD2_k127_3625758_0	1459636.NTE_01784	1.418e-63	226.0	COG0147@1|root,arCOG02014@2157|Archaea,41S8W@651137|Thaumarchaeota	651137|Thaumarchaeota	E	component I	-	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
YYD2_k127_3635174_3	1459636.NTE_02745	2.068e-11	67.0	COG0049@1|root,arCOG04254@2157|Archaea,41S6U@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YYD2_k127_3635174_0	1459636.NTE_02746	3.768e-79	265.0	COG0048@1|root,arCOG04255@2157|Archaea,41SIB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits	rps12	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
YYD2_k127_3635174_1	1459636.NTE_02747	3.917e-68	234.0	COG0195@1|root,arCOG01760@2157|Archaea,41SJQ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_2
YYD2_k127_3635174_2	1459636.NTE_02748	3.095e-17	84.0	COG1911@1|root,arCOG01752@2157|Archaea,41SW9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	PFAM ribosomal protein L7Ae L30e S12e Gadd45	-	-	-	ko:K02908	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L7Ae
YYD2_k127_368754_1	1041159.AZUW01000012_gene2253	1.981e-08	60.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4BB16@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HCBP_related,He_PIG,HemolysinCabind,Metallophos
YYD2_k127_368754_0	1459636.NTE_00560	2.955e-26	112.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3698121_1	1459636.NTE_01151	1.409e-64	229.0	arCOG06256@1|root,arCOG06256@2157|Archaea	2157|Archaea	S	phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
YYD2_k127_3698121_0	1459636.NTE_01150	1.525e-136	441.0	COG0346@1|root,arCOG03101@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD2_k127_373365_0	203119.Cthe_0699	7.44e-105	344.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae	186801|Clostridia	I	Carboxyl transferase domain	yqjD	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YYD2_k127_373365_1	1459636.NTE_02333	8.955e-10	64.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_374239_0	5911.EAR82403	0.000408	43.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
YYD2_k127_376564_1	436308.Nmar_1268	5.735e-163	517.0	COG0646@1|root,arCOG08715@2157|Archaea,41SWZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
YYD2_k127_376564_0	1459636.NTE_02986	1.413e-245	768.0	COG0294@1|root,COG1410@1|root,arCOG01978@2157|Archaea,arCOG02029@2157|Archaea,41SXT@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind
YYD2_k127_3766040_1	436308.Nmar_1326	2.369e-08	57.0	COG3398@1|root,arCOG02611@2157|Archaea	436308.Nmar_1326|-	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3766040_0	248742.XP_005649230.1	4.32e-16	89.0	COG1409@1|root,KOG1378@2759|Eukaryota	2759|Eukaryota	E	acid phosphatase activity	-	-	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos
YYD2_k127_3767561_0	1459636.NTE_02122	2.825e-122	403.0	COG1744@1|root,arCOG00257@2157|Archaea	2157|Archaea	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
YYD2_k127_3775767_4	1459636.NTE_02897	7.886e-14	72.0	COG1475@1|root,arCOG11113@2157|Archaea,41SYF@651137|Thaumarchaeota	651137|Thaumarchaeota	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YYD2_k127_3775767_0	1459636.NTE_02873	1.517e-92	310.0	COG1028@1|root,arCOG01259@2157|Archaea,41SXY@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YYD2_k127_3775767_1	1459636.NTE_02296	6.964e-42	167.0	arCOG00059@1|root,arCOG00059@2157|Archaea,41T4Y@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3775767_2	1459636.NTE_00416	7.931e-41	158.0	COG0484@1|root,COG1141@1|root,arCOG00349@2157|Archaea,arCOG02846@2157|Archaea,41ST0@651137|Thaumarchaeota	651137|Thaumarchaeota	CO	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,Fer4_13
YYD2_k127_3775767_3	391623.TERMP_00024	5.729e-36	146.0	COG3769@1|root,arCOG01215@2157|Archaea,2XZBT@28890|Euryarchaeota,242XQ@183968|Thermococci	183968|Thermococci	S	Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG)	mngB	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
YYD2_k127_3781859_4	1459636.NTE_02046	2.129e-31	125.0	COG0381@1|root,arCOG01392@2157|Archaea	2157|Archaea	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
YYD2_k127_3781859_5	1459636.NTE_02047	6.89e-26	112.0	arCOG08683@1|root,arCOG08683@2157|Archaea,41SUM@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3781859_1	1459636.NTE_02048	1.33e-141	456.0	COG1085@1|root,arCOG00422@2157|Archaea,41S6T@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
YYD2_k127_3781859_3	1459636.NTE_03311	1.032e-34	134.0	arCOG08782@1|root,arCOG08782@2157|Archaea,41SVH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3781859_0	1459636.NTE_01905	4.049e-154	493.0	COG0057@1|root,arCOG00493@2157|Archaea,41SDF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	-
YYD2_k127_3781859_2	1459636.NTE_01906	1.109e-83	281.0	COG0512@1|root,arCOG00086@2157|Archaea,41SGV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YYD2_k127_3781859_6	579137.Metvu_1679	4.526e-16	81.0	COG0547@1|root,arCOG02012@2157|Archaea,2XT3C@28890|Euryarchaeota,23QA4@183939|Methanococci	183939|Methanococci	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
YYD2_k127_3811440_0	1459636.NTE_00865	1.9e-85	285.0	COG0306@1|root,arCOG02267@2157|Archaea,41SD8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
YYD2_k127_3811440_1	1459636.NTE_00638	1.003e-73	252.0	COG2406@1|root,arCOG01093@2157|Archaea	2157|Archaea	S	COG2406 Protein distantly related to bacterial ferritins	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
YYD2_k127_3811440_3	1459636.NTE_02281	5.995e-51	188.0	COG2226@1|root,arCOG04348@2157|Archaea	2157|Archaea	H	Methyltransferase	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
YYD2_k127_3811440_2	1459636.NTE_02280	2.909e-69	242.0	COG1575@1|root,arCOG00480@2157|Archaea,41SNA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the MenA family. Type 1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3811440_5	1459636.NTE_02279	4.661e-15	81.0	COG3161@1|root,arCOG01031@2157|Archaea	2157|Archaea	H	4-hydroxybenzoate synthetase (chorismate lyase)	-	-	2.4.2.54,4.1.3.40	ko:K03181,ko:K06984	ko00130,ko00790,ko01100,ko01110,map00130,map00790,map01100,map01110	M00117	R01302,R10337,R11102	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF98,GHMP_kinases_C,GHMP_kinases_N
YYD2_k127_3811440_6	1298865.H978DRAFT_3635	7.306e-15	78.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,1S8IP@1236|Gammaproteobacteria,467J8@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Peptidase_M23
YYD2_k127_3816151_0	1158338.JNLJ01000005_gene1373	3.337e-75	262.0	COG0338@1|root,COG0338@2|Bacteria,2G4QA@200783|Aquificae	200783|Aquificae	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
YYD2_k127_3821426_0	1232437.KL662010_gene1646	2.743e-10	66.0	COG1553@1|root,COG1553@2|Bacteria,1NBVC@1224|Proteobacteria,42WGH@68525|delta/epsilon subdivisions,2WRSA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
YYD2_k127_382974_0	247490.KSU1_D0999	5.215e-17	94.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
YYD2_k127_3837021_0	1459636.NTE_00085	4.406e-171	552.0	COG1311@1|root,arCOG04455@2157|Archaea,41T0D@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	-	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B
YYD2_k127_3837021_1	1459636.NTE_00060	4.172e-45	168.0	arCOG01995@1|root,arCOG01995@2157|Archaea,41T3M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
YYD2_k127_3837021_2	290397.Adeh_0061	3.669e-08	55.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2YVGX@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YYD2_k127_3837620_0	1459636.NTE_01057	4.528e-63	226.0	COG1599@1|root,arCOG01510@2157|Archaea,41S9M@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
YYD2_k127_3852586_0	1459636.NTE_02196	1.507e-174	560.0	COG1793@1|root,arCOG01347@2157|Archaea,41SCK@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
YYD2_k127_3852586_2	1459636.NTE_02195	5.346e-16	81.0	COG4901@1|root,arCOG04327@2157|Archaea,41SUF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	S25 ribosomal protein	-	-	-	ko:K02975	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S25
YYD2_k127_3852586_1	1459636.NTE_02194	2.128e-19	93.0	COG2164@1|root,arCOG04488@2157|Archaea,41STM@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
YYD2_k127_3856675_2	1459636.NTE_03100	3.117e-11	66.0	COG1872@1|root,arCOG04058@2157|Archaea,41TAX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
YYD2_k127_3856675_0	436308.Nmar_0111	2.771e-68	233.0	COG0432@1|root,arCOG04214@2157|Archaea,41T31@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YYD2_k127_3864080_1	1131266.ARWQ01000001_gene1353	8.808e-36	142.0	COG1514@1|root,arCOG01736@2157|Archaea,41SP7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
YYD2_k127_3864080_2	1232449.BAHV02000021_gene1129	2.829e-15	80.0	COG0745@1|root,COG0745@2|Bacteria,1U4FM@1239|Firmicutes,24DF2@186801|Clostridia,268RY@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K18344	ko01502,ko02020,map01502,map02020	M00651,M00656	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_3864080_0	1459636.NTE_00994	3.749e-46	168.0	COG1454@1|root,arCOG00984@2157|Archaea,41SFC@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Iron-containing alcohol dehydrogenase	-	-	-	ko:K18602	ko00720,ko01120,map00720,map01120	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
YYD2_k127_387833_0	1459636.NTE_02717	4.075e-92	308.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	fgd-2	-	1.1.98.2,1.1.98.5	ko:K15510,ko:K21835	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
YYD2_k127_3887723_0	1459636.NTE_01932	6.093e-95	326.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
YYD2_k127_3887723_1	1457250.BBMO01000002_gene2461	6.967e-25	117.0	arCOG07550@1|root,arCOG07550@2157|Archaea,2XTFE@28890|Euryarchaeota,23U84@183963|Halobacteria	183963|Halobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF726,DUF900
YYD2_k127_3910190_1	1131266.ARWQ01000014_gene97	1.213e-39	149.0	arCOG06790@1|root,arCOG06790@2157|Archaea,41T7J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
YYD2_k127_3912223_1	1459636.NTE_01263	1.196e-17	85.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_3912223_0	1229909.NSED_01010	5.826e-64	227.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD2_k127_3920078_0	1459636.NTE_00523	4.553e-128	419.0	COG2262@1|root,arCOG00353@2157|Archaea,41SD4@651137|Thaumarchaeota	2157|Archaea	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877	-	ko:K03665,ko:K06883	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YYD2_k127_392792_0	1459636.NTE_01491	5.136e-06	53.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_39358_3	877455.Metbo_0232	5.735e-08	55.0	COG0068@1|root,arCOG01187@2157|Archaea,2XTHZ@28890|Euryarchaeota,23NPD@183925|Methanobacteria	183925|Methanobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
YYD2_k127_39358_1	269797.Mbar_A0382	2.523e-71	252.0	COG0068@1|root,arCOG01187@2157|Archaea,2XTHZ@28890|Euryarchaeota,2N9FC@224756|Methanomicrobia	224756|Methanomicrobia	O	TIGRFAM NiFe hydrogenase maturation protein HypF	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
YYD2_k127_39358_2	399549.Msed_0931	7.453e-19	89.0	COG0298@1|root,arCOG04427@2157|Archaea	2157|Archaea	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
YYD2_k127_39358_0	399549.Msed_0930	4.553e-140	454.0	COG0409@1|root,arCOG04428@2157|Archaea,2XPKY@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM hydrogenase formation HypD protein	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
YYD2_k127_3938490_1	930171.Asphe3_17720	1.785e-12	70.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria	201174|Actinobacteria	L	DNA primase, small subunit	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_primase_S
YYD2_k127_3938490_0	1459636.NTE_01596	3.04e-15	80.0	arCOG08725@1|root,arCOG08725@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_39911_0	1459636.NTE_02163	6.647e-09	68.0	arCOG08635@1|root,arCOG08635@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3996067_0	1459636.NTE_02663	1.654e-171	545.0	COG2046@1|root,arCOG04191@2157|Archaea,41SER@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
YYD2_k127_3996067_1	1459636.NTE_02682	1.003e-05	51.0	arCOG08818@1|root,arCOG08818@2157|Archaea,41SVV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3999367_0	1123504.JQKD01000002_gene3793	2.069e-12	66.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2VJQ2@28216|Betaproteobacteria,4A9SP@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
YYD2_k127_4006706_0	795359.TOPB45_0496	5.645e-49	188.0	COG0303@1|root,COG0303@2|Bacteria,2GGXT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	MoeA C-terminal region (domain IV)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
YYD2_k127_4006706_1	859653.HIMB5_00003360	5.976e-18	90.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,2U7QA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YYD2_k127_4026284_0	1459636.NTE_02677	4.687e-94	317.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4026284_1	1459636.NTE_00597	2.154e-19	88.0	COG3945@1|root,arCOG01471@2157|Archaea,41T45@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YYD2_k127_4034504_0	1107311.Q767_02285	4.249e-08	64.0	COG2244@1|root,COG2244@2|Bacteria,4NI85@976|Bacteroidetes,1HXZ7@117743|Flavobacteriia,2NUZC@237|Flavobacterium	976|Bacteroidetes	S	biosynthesis protein	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_3
YYD2_k127_4034504_1	167542.P9515_13891	0.0001126	49.0	COG1215@1|root,COG1215@2|Bacteria,1GQJV@1117|Cyanobacteria,1MPPJ@1212|Prochloraceae	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_4042825_2	1459636.NTE_00916	2.86e-28	114.0	COG1010@1|root,arCOG00647@2157|Archaea,41S6W@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.131	ko:K05934	ko00860,ko01100,map00860,map01100	-	R05180,R05809	RC00003,RC01293,RC03471	ko00000,ko00001,ko01000	-	-	-	TP_methylase
YYD2_k127_4042825_0	1459636.NTE_00933	4.847e-185	589.0	COG0527@1|root,arCOG00861@2157|Archaea,41SFA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
YYD2_k127_4042825_1	1459636.NTE_00934	3.913e-90	300.0	COG0592@1|root,arCOG00488@2157|Archaea,41S6E@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication	pcn	-	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
YYD2_k127_4064688_1	1459636.NTE_02202	1.193e-17	85.0	COG1018@1|root,COG2146@1|root,arCOG02200@2157|Archaea,arCOG02852@2157|Archaea	2157|Archaea	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	DAO,FAD_binding_6,NAD_binding_1,Rieske,Rieske_2
YYD2_k127_4064688_0	1459636.NTE_00744	1.971e-19	88.0	COG0657@1|root,arCOG02638@2157|Archaea	2157|Archaea	I	Alpha beta hydrolase	-	-	3.1.1.83	ko:K01066,ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
YYD2_k127_40652_0	1459636.NTE_01001	7.921e-78	274.0	arCOG10517@1|root,arCOG10517@2157|Archaea,41T0I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_40652_1	458817.Shal_1886	1.167e-40	160.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,2QDMX@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Sulfatase	atsA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YYD2_k127_4081482_6	1459636.NTE_03116	1.482e-83	288.0	COG1270@1|root,arCOG04274@2157|Archaea,41S6I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
YYD2_k127_4081482_11	1459636.NTE_03117	5.175e-44	169.0	COG0368@1|root,arCOG04338@2157|Archaea,41SI6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
YYD2_k127_4081482_18	386456.JQKN01000013_gene3046	5.212e-20	98.0	COG2266@1|root,arCOG01871@2157|Archaea,2XZP4@28890|Euryarchaeota,23P5D@183925|Methanobacteria	183925|Methanobacteria	M	Cytidylyltransferase	cobY	-	2.7.7.62	ko:K19712	ko00860,ko01100,map00860,map01100	-	R05222	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
YYD2_k127_4081482_19	1459636.NTE_03119	1.367e-16	80.0	COG2051@1|root,arCOG04108@2157|Archaea,41SUD@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	rps27e	-	-	ko:K02978	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S27e
YYD2_k127_4081482_12	1459636.NTE_03120	2.433e-43	159.0	COG1631@1|root,arCOG04109@2157|Archaea,41SQZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl44e	-	-	ko:K02929	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L44
YYD2_k127_4081482_13	1459636.NTE_01466	2.528e-36	145.0	arCOG03727@1|root,arCOG03727@2157|Archaea,41STD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
YYD2_k127_4081482_14	1459636.NTE_03107	3.06e-33	130.0	COG2118@1|root,arCOG04179@2157|Archaea,41SR0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the PDCD5 family	-	-	-	ko:K06875	-	-	-	-	ko00000	-	-	-	dsDNA_bind
YYD2_k127_4081482_8	1459636.NTE_03108	2.215e-61	214.0	COG2238@1|root,arCOG01344@2157|Archaea,41SK1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	May be involved in maturation of the 30S ribosomal subunit	rps19e	-	-	ko:K02966	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19e
YYD2_k127_4081482_15	1459636.NTE_03109	4.937e-23	101.0	COG2023@1|root,arCOG04345@2157|Archaea,41STS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp4	-	3.1.26.5	ko:K03540	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rpr2
YYD2_k127_4081482_9	436308.Nmar_1625	4.924e-51	190.0	COG1756@1|root,arCOG04122@2157|Archaea,41T2T@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA	nep1	-	2.1.1.260	ko:K14568	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009	-	-	-	EMG1
YYD2_k127_4081482_4	1459636.NTE_01313	1.107e-103	353.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41SXB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4081482_2	1459636.NTE_02299	2.284e-122	400.0	COG2835@1|root,arCOG01792@1|root,arCOG01792@2157|Archaea,arCOG04124@2157|Archaea,41T4S@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4081482_1	1459636.NTE_01915	1.469e-130	427.0	COG1474@1|root,arCOG00467@2157|Archaea,41SED@651137|Thaumarchaeota	2157|Archaea	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22
YYD2_k127_4081482_17	1459636.NTE_01916	1.166e-22	100.0	COG0640@1|root,arCOG04056@2157|Archaea	2157|Archaea	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5,TrmB
YYD2_k127_4081482_5	1459636.NTE_00432	4.038e-100	339.0	COG0446@1|root,arCOG01064@2157|Archaea,41SZR@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YYD2_k127_4081482_10	1459636.NTE_03214	1.401e-48	176.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4081482_0	1459636.NTE_03216	0.0	1130.0	COG0525@1|root,arCOG00808@2157|Archaea,41SBK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Anticodon-binding domain of tRNA	-	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
YYD2_k127_4081482_3	1459636.NTE_00856	2.153e-104	345.0	COG0720@1|root,arCOG02172@2157|Archaea,41SY8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
YYD2_k127_4081482_7	1459636.NTE_00858	1.439e-67	238.0	COG0367@1|root,arCOG00071@2157|Archaea,41SIX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
YYD2_k127_4081482_16	1459636.NTE_02931	1.113e-22	100.0	COG0015@1|root,arCOG01747@2157|Archaea,41SD1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	adenylosuccinate lyase	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
YYD2_k127_4082072_1	1131266.ARWQ01000011_gene108	1.717e-37	149.0	COG4301@1|root,arCOG06722@2157|Archaea,41SWR@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
YYD2_k127_4082072_0	221288.JH992901_gene3607	1.08e-142	459.0	COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria,1JIY9@1189|Stigonemataceae	1117|Cyanobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_4082072_2	1405.DJ92_4756	1.476e-13	73.0	COG0382@1|root,COG0382@2|Bacteria,1UZUK@1239|Firmicutes,4HDQ2@91061|Bacilli	91061|Bacilli	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
YYD2_k127_4087101_0	1459636.NTE_03523	1.278e-88	308.0	COG3391@1|root,arCOG08716@1|root,arCOG02562@2157|Archaea,arCOG08716@2157|Archaea	2157|Archaea	Q	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,PKD
YYD2_k127_409927_1	673860.AciM339_0102	5.323e-28	116.0	COG1228@1|root,arCOG00696@2157|Archaea,2XVAU@28890|Euryarchaeota,3F2Z2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD2_k127_409927_0	1459636.NTE_02849	1.259e-188	625.0	COG4257@1|root,arCOG06267@1|root,arCOG03564@2157|Archaea,arCOG06267@2157|Archaea,41S5S@651137|Thaumarchaeota	651137|Thaumarchaeota	V	resistance protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
YYD2_k127_409927_2	1459636.NTE_00228	3.229e-13	77.0	arCOG08825@1|root,arCOG08825@2157|Archaea	1459636.NTE_00228|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4100237_0	1306947.ARQD01000001_gene702	1.899e-70	244.0	COG0778@1|root,COG0778@2|Bacteria,2NPZS@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YYD2_k127_4123066_2	1459636.NTE_01048	5.86e-64	225.0	COG0624@1|root,arCOG01110@2157|Archaea,41SAE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YYD2_k127_4123066_1	1459636.NTE_02137	3.519e-95	315.0	COG1945@1|root,arCOG04490@2157|Archaea,41SPZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the PdaD family	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
YYD2_k127_4123066_3	1056495.Calag_0594	2.261e-27	117.0	COG1656@1|root,arCOG04290@2157|Archaea,2XQD5@28889|Crenarchaeota	28889|Crenarchaeota	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
YYD2_k127_4123066_0	1459636.NTE_01231	4.03e-312	964.0	COG1048@1|root,arCOG01697@2157|Archaea,41SE6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YYD2_k127_4127522_0	1386089.N865_08770	3.097e-06	58.0	COG1361@1|root,COG2931@1|root,COG3210@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.2.1.65	ko:K01212,ko:K12287,ko:K20276	ko00500,ko02024,map00500,map02024	-	R05624,R11311	RC03278	ko00000,ko00001,ko01000,ko02044	-	GH32	-	Big_3_2,DUF11,HemolysinCabind,SdrD_B
YYD2_k127_413008_0	1459636.NTE_02722	6.673e-246	774.0	COG2511@1|root,arCOG01719@2157|Archaea,41S8Q@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatE	-	6.3.5.7	ko:K03330	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	GAD,GatB_N,GatB_Yqey
YYD2_k127_413008_1	1459636.NTE_02721	6.347e-34	133.0	COG0252@1|root,arCOG01924@2157|Archaea,41SD7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatD	-	6.3.5.7	ko:K09482	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	Asparaginase
YYD2_k127_4141090_1	1459636.NTE_03208	1.072e-93	310.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
YYD2_k127_4141090_0	1459636.NTE_03207	8.435e-199	628.0	COG0019@1|root,arCOG02268@2157|Archaea	2157|Archaea	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.17,4.1.1.20,4.1.1.96	ko:K01581,ko:K01586,ko:K13747	ko00300,ko00330,ko00480,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map00480,map01100,map01110,map01120,map01130,map01230	M00016,M00134,M00525,M00526,M00527	R00451,R00670,R09081,R09082	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2177	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YYD2_k127_4141090_2	1123371.ATXH01000003_gene1973	1.036e-22	101.0	COG1254@1|root,COG1254@2|Bacteria,2GHZK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YYD2_k127_4141090_3	1459636.NTE_03205	4.505e-19	90.0	arCOG10515@1|root,arCOG10515@2157|Archaea,41TAP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4152138_0	1229909.NSED_08545	2.218e-08	63.0	arCOG11548@1|root,arCOG11548@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4169235_2	985053.VMUT_0862	4.114e-24	107.0	COG1313@1|root,arCOG00934@2157|Archaea,2XPK3@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
YYD2_k127_4169235_0	1038859.AXAU01000014_gene1378	8.827e-108	356.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria	1224|Proteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
YYD2_k127_4169235_1	1459636.NTE_02717	1.731e-56	201.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	fgd-2	-	1.1.98.2,1.1.98.5	ko:K15510,ko:K21835	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
YYD2_k127_4192176_0	1459636.NTE_01493	2.353e-45	175.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YYD2_k127_4203937_0	1459636.NTE_00198	2.083e-24	105.0	arCOG06947@1|root,arCOG06947@2157|Archaea,41TAK@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4207100_3	1459636.NTE_02430	2.898e-53	195.0	COG1651@1|root,arCOG02868@2157|Archaea,41T2W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YYD2_k127_4207100_7	1459636.NTE_02864	6.53e-21	94.0	COG1996@1|root,arCOG04341@2157|Archaea,41SWH@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	-
YYD2_k127_4207100_6	1459636.NTE_00660	3.702e-21	93.0	arCOG08687@1|root,arCOG08687@2157|Archaea,41SVF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4207100_5	1459636.NTE_02126	9.154e-31	124.0	COG1599@1|root,arCOG01510@2157|Archaea,41SV1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	tRNA_anti-codon
YYD2_k127_4207100_2	1459636.NTE_03018	1.293e-70	243.0	COG0221@1|root,arCOG01711@2157|Archaea,41T3F@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
YYD2_k127_4207100_0	1459636.NTE_03020	1.741e-191	604.0	COG0464@1|root,arCOG01307@2157|Archaea,41SA4@651137|Thaumarchaeota	651137|Thaumarchaeota	D	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,MIT,Vps4_C
YYD2_k127_4207100_1	1459636.NTE_01454	1.382e-134	441.0	COG1061@1|root,arCOG00874@2157|Archaea,41SW0@651137|Thaumarchaeota	2157|Archaea	K	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
YYD2_k127_4207100_4	1459636.NTE_01455	6.243e-51	185.0	COG2042@1|root,arCOG04733@2157|Archaea,41SMC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Ribosome biogenesis protein, C-terminal	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	RLI,Ribo_biogen_C
YYD2_k127_4220009_0	1459636.NTE_02508	1.778e-64	228.0	arCOG06353@1|root,arCOG06353@2157|Archaea,41SI1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Probable cobalt transporter subunit (CbtA)	-	-	-	-	-	-	-	-	-	-	-	-	CbtA
YYD2_k127_4220009_3	1229909.NSED_04935	3.071e-20	91.0	arCOG08746@1|root,arCOG08746@2157|Archaea,41SWA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Probable cobalt transporter subunit (CbtB)	-	-	-	-	-	-	-	-	-	-	-	-	CbtB
YYD2_k127_4220009_1	1459636.NTE_02510	6.259e-62	222.0	arCOG02103@1|root,arCOG02103@2157|Archaea,41T51@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF4443)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4443
YYD2_k127_4220009_2	1459636.NTE_00264	2.796e-51	185.0	arCOG01792@1|root,arCOG01792@2157|Archaea	2157|Archaea	K	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YYD2_k127_4221435_0	1459636.NTE_02845	2.782e-39	152.0	COG3398@1|root,arCOG02611@2157|Archaea,41T7Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
YYD2_k127_4223709_1	1459636.NTE_02918	2.452e-06	51.0	arCOG08706@1|root,arCOG08706@2157|Archaea,41SUP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4223709_0	1459636.NTE_00668	4.616e-99	331.0	COG1063@1|root,arCOG01459@2157|Archaea	2157|Archaea	C	Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a	fdh	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
YYD2_k127_424861_1	368407.Memar_1722	2.832e-06	49.0	COG4294@1|root,arCOG01898@2157|Archaea,2XVT2@28890|Euryarchaeota	28890|Euryarchaeota	L	UV-endonuclease UvdE	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
YYD2_k127_424861_0	926549.KI421517_gene2554	1.363e-63	224.0	COG4294@1|root,COG4294@2|Bacteria,4NIZA@976|Bacteroidetes,47K7P@768503|Cytophagia	976|Bacteroidetes	L	UV-endonuclease UvdE	-	-	-	-	-	-	-	-	-	-	-	-	UvdE
YYD2_k127_4262308_0	111780.Sta7437_0068	2.494e-12	72.0	COG2931@1|root,COG2931@2|Bacteria,1G2KD@1117|Cyanobacteria,3VK0E@52604|Pleurocapsales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lipase_GDSL_2
YYD2_k127_4265146_0	46234.ANA_C13160	8.169e-45	172.0	COG0463@1|root,COG0463@2|Bacteria,1GQ4G@1117|Cyanobacteria,1HN6Q@1161|Nostocales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11
YYD2_k127_4270334_0	3075.A0A087SH19	7.298e-06	50.0	COG0596@1|root,2SD7I@2759|Eukaryota	2759|Eukaryota	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DLH,Hydrolase_4
YYD2_k127_4270334_1	1459636.NTE_01183	0.000449	46.0	COG0582@1|root,arCOG01242@2157|Archaea	2157|Archaea	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase,zinc_ribbon_2
YYD2_k127_427461_1	436308.Nmar_1418	2.136e-41	164.0	COG0284@1|root,arCOG00081@2157|Archaea,41SMN@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
YYD2_k127_427461_0	1459636.NTE_00654	1.339e-63	225.0	arCOG08773@1|root,arCOG08773@2157|Archaea,41SNY@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_427461_2	1324957.K933_16517	0.0004157	50.0	arCOG07781@1|root,arCOG07781@2157|Archaea,2XVFT@28890|Euryarchaeota,23V0T@183963|Halobacteria	183963|Halobacteria	P	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Glucodextran_C,Malectin,REJ
YYD2_k127_4302796_0	1459636.NTE_01739	6.74e-156	498.0	COG0644@1|root,arCOG00570@2157|Archaea,41SCG@651137|Thaumarchaeota	2157|Archaea	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,NAD_binding_8,Pyr_redox_2
YYD2_k127_4302796_2	1459636.NTE_02166	1.344e-20	94.0	arCOG11431@1|root,arCOG11431@2157|Archaea,41T8G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4302796_1	1459636.NTE_01450	1.957e-37	145.0	COG0001@1|root,arCOG00918@2157|Archaea,41S5Y@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YYD2_k127_430283_1	1459636.NTE_03552	4.784e-90	302.0	COG0123@1|root,arCOG00324@2157|Archaea	2157|Archaea	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
YYD2_k127_430283_2	1459636.NTE_01553	2.373e-29	121.0	arCOG12283@1|root,arCOG12283@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_430283_3	1123355.JHYO01000015_gene1958	5.314e-15	79.0	COG0745@1|root,COG0745@2|Bacteria,1N9SP@1224|Proteobacteria,2U6CP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	cheY-homologous receiver domain	MA20_29080	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD2_k127_430283_0	1459636.NTE_01496	1.265e-163	533.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_4303138_2	1459636.NTE_01953	6.815e-35	138.0	COG1685@1|root,arCOG01025@2157|Archaea,41SGZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	GHMP kinases N terminal domain	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YYD2_k127_4303138_0	1459636.NTE_01954	2.606e-97	325.0	COG0169@1|root,arCOG01033@2157|Archaea,41S6G@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
YYD2_k127_4303138_1	436308.Nmar_0551	4.295e-56	203.0	COG0169@1|root,arCOG02097@2157|Archaea,41SKU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I
YYD2_k127_4303344_1	679926.Mpet_2032	4.465e-45	166.0	COG1742@1|root,arCOG07820@2157|Archaea,2XYGR@28890|Euryarchaeota,2NBC8@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM Uncharacterised BCR, YnfA UPF0060 family	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
YYD2_k127_4303344_0	436308.Nmar_1681	1.597e-48	176.0	COG1742@1|root,arCOG07820@2157|Archaea,41TAS@651137|Thaumarchaeota	436308.Nmar_1681|-	S	Uncharacterised BCR, YnfA/UPF0060 family	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	-
YYD2_k127_4304136_2	1229520.ADIAL_1578	2.486e-16	81.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,27GW3@186828|Carnobacteriaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
YYD2_k127_4304136_1	1229909.NSED_06665	1.644e-16	84.0	COG2132@1|root,COG3794@1|root,arCOG02926@2157|Archaea,arCOG03914@2157|Archaea,41SWV@651137|Thaumarchaeota	651137|Thaumarchaeota	CQ	multicopper	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
YYD2_k127_4304136_0	1459636.NTE_00888	3.485e-24	106.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
YYD2_k127_4306315_2	1459636.NTE_03312	2.4e-45	167.0	arCOG02703@1|root,arCOG02703@2157|Archaea	2157|Archaea	S	Methyltransferase type 11	aknG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
YYD2_k127_4306315_3	1459636.NTE_03311	1.786e-37	141.0	arCOG08782@1|root,arCOG08782@2157|Archaea,41SVH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4306315_0	1459636.NTE_03310	4.497e-63	216.0	COG1145@1|root,arCOG00291@2157|Archaea,41SNB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	NADH ubiquinone oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
YYD2_k127_4306315_4	1459636.NTE_03303	6.431e-36	143.0	COG1936@1|root,arCOG01038@2157|Archaea,41SPH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
YYD2_k127_4306315_1	1459636.NTE_03306	7.082e-59	207.0	COG1958@1|root,arCOG00999@2157|Archaea	2157|Archaea	K	PFAM Like-Sm ribonucleoprotein, core	-	-	-	-	-	-	-	-	-	-	-	-	LSM,Lsm_C,SM-ATX
YYD2_k127_4306315_5	1459636.NTE_03307	3.267e-31	124.0	COG0343@1|root,arCOG00989@2157|Archaea,41SF4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs	tgtA	-	2.4.2.48	ko:K18779	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TGT
YYD2_k127_4311339_0	1459636.NTE_03212	7.458e-241	751.0	COG0516@1|root,arCOG00612@2157|Archaea,41S7R@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
YYD2_k127_433358_0	686340.Metal_2216	1.505e-18	93.0	2C5IF@1|root,2Z9B7@2|Bacteria,1R5AB@1224|Proteobacteria,1SJEE@1236|Gammaproteobacteria,1XGBF@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF1264)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1264
YYD2_k127_4356370_0	1459636.NTE_03260	2.349e-81	286.0	arCOG10517@1|root,arCOG10517@2157|Archaea,41T0I@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4360133_0	1537715.JQFJ01000002_gene1310	3.494e-07	61.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2K0IP@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,He_PIG,HemolysinCabind
YYD2_k127_4365818_0	263820.PTO0362	0.0009359	48.0	COG0582@1|root,arCOG01242@2157|Archaea	2157|Archaea	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase,zinc_ribbon_2
YYD2_k127_4369041_0	1459636.NTE_01820	1.644e-41	160.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_4379374_0	1459636.NTE_01491	2.916e-23	104.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4379374_2	484770.UFO1_2525	0.0008962	48.0	COG0726@1|root,COG0726@2|Bacteria,1UYYJ@1239|Firmicutes,4H3MV@909932|Negativicutes	909932|Negativicutes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
YYD2_k127_4379374_1	378806.STAUR_5639	0.0005679	45.0	COG0726@1|root,COG0726@2|Bacteria,1Q3PB@1224|Proteobacteria,439GJ@68525|delta/epsilon subdivisions,2X4SI@28221|Deltaproteobacteria,2YZHY@29|Myxococcales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
YYD2_k127_4385566_3	1459636.NTE_01953	1.93e-52	190.0	COG1685@1|root,arCOG01025@2157|Archaea,41SGZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	GHMP kinases N terminal domain	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YYD2_k127_4385566_2	1459636.NTE_01952	3.433e-145	471.0	COG0128@1|root,arCOG04134@2157|Archaea,41S5I@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
YYD2_k127_4385566_0	1459636.NTE_01951	1.979e-170	541.0	COG0082@1|root,arCOG04133@2157|Archaea,41SC3@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
YYD2_k127_4385566_1	1459636.NTE_01950	2.95e-153	496.0	COG0436@1|root,COG1605@1|root,arCOG01130@2157|Archaea,arCOG02098@2157|Archaea,41SBV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Chorismate mutase type II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,CM_2
YYD2_k127_4385566_4	1459636.NTE_01949	1.1e-51	194.0	COG0722@1|root,arCOG00245@2157|Archaea,41SM0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
YYD2_k127_4386887_0	1459636.NTE_02436	4.234e-34	141.0	arCOG02527@1|root,arCOG02527@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NosD
YYD2_k127_4387728_1	1131266.ARWQ01000002_gene508	6.819e-24	101.0	COG0017@1|root,arCOG00406@2157|Archaea,41SBT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	-	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YYD2_k127_4387728_2	1459636.NTE_02819	1.34e-10	66.0	COG0721@1|root,arCOG02726@2157|Archaea	2157|Archaea	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
YYD2_k127_4387728_0	1459636.NTE_02818	1.233e-61	216.0	COG0154@1|root,arCOG01717@2157|Archaea,41SCW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD2_k127_4392278_0	1121904.ARBP01000001_gene5559	6.015e-43	162.0	COG3542@1|root,COG3542@2|Bacteria,4NPCH@976|Bacteroidetes,47PD8@768503|Cytophagia	976|Bacteroidetes	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
YYD2_k127_43939_0	445335.CBN_1772	2.476e-67	240.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,36EPX@31979|Clostridiaceae	186801|Clostridia	C	Dihydrolipoyl dehydrogenase	acoL	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
YYD2_k127_43939_1	1408428.JNJP01000077_gene2810	2.429e-08	57.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	yhdJ	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
YYD2_k127_4398363_0	1459636.NTE_01509	4.587e-29	127.0	arCOG02362@1|root,arCOG02362@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
YYD2_k127_4402102_1	1459636.NTE_02436	8.561e-67	244.0	arCOG02527@1|root,arCOG02527@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NosD
YYD2_k127_4402102_0	391587.KAOT1_19772	7.147e-79	272.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD2_k127_4403193_1	1459636.NTE_01033	8.339e-39	149.0	arCOG03681@1|root,arCOG03681@2157|Archaea,41T6V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4403193_0	1459636.NTE_01032	8.272e-188	595.0	COG0661@1|root,arCOG01189@2157|Archaea,41SYQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
YYD2_k127_4417306_6	1459636.NTE_01726	4.233e-34	132.0	COG0192@1|root,arCOG07444@2157|Archaea,41S5P@651137|Thaumarchaeota	651137|Thaumarchaeota	H	S-adenosylmethionine synthetase	-	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YYD2_k127_4417306_7	1459636.NTE_01725	5.802e-32	128.0	COG1958@1|root,arCOG00998@2157|Archaea,41SS5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	snRNP Sm proteins	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
YYD2_k127_4417306_4	1459636.NTE_01724	3.605e-37	149.0	COG0468@1|root,arCOG00417@2157|Archaea,41SQC@651137|Thaumarchaeota	651137|Thaumarchaeota	T	RecA RadA	-	-	-	ko:K04482,ko:K04483	ko03440,ko03460,ko05200,ko05212,map03440,map03460,map05200,map05212	-	-	-	ko00000,ko00001,ko03400,ko04121,ko04131	-	-	-	Rad51
YYD2_k127_4417306_5	1459636.NTE_01897	1.629e-36	143.0	COG2016@1|root,arCOG00985@2157|Archaea,41SSC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	PUA domain	-	-	-	ko:K07575	-	-	-	-	ko00000	-	-	-	PUA
YYD2_k127_4417306_1	1459636.NTE_02917	5.139e-186	587.0	COG0372@1|root,arCOG04237@2157|Archaea,41SAN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM 2-methylcitrate synthase citrate synthase II	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
YYD2_k127_4417306_3	1459636.NTE_01899	4.348e-85	286.0	COG0638@1|root,arCOG00970@2157|Archaea,41SGS@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
YYD2_k127_4417306_0	1459636.NTE_01900	1.712e-192	615.0	COG0323@1|root,arCOG01166@2157|Archaea	2157|Archaea	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
YYD2_k127_4417306_2	1459636.NTE_00712	5.133e-91	304.0	COG0244@1|root,arCOG04288@2157|Archaea,41S9R@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl10	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
YYD2_k127_4461499_1	1144275.COCOR_05798	1.595e-09	69.0	COG2303@1|root,COG2303@2|Bacteria,1NV3A@1224|Proteobacteria,439HF@68525|delta/epsilon subdivisions,2X4TQ@28221|Deltaproteobacteria,2YZK5@29|Myxococcales	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
YYD2_k127_4461499_0	446470.Snas_0664	1.707e-15	90.0	COG2730@1|root,COG2730@2|Bacteria,2HQAQ@201174|Actinobacteria,4EZ87@85014|Glycomycetales	201174|Actinobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.123	ko:K05991	-	-	-	-	ko00000,ko01000	-	GH5	-	Cellulase
YYD2_k127_4467380_0	1459636.NTE_01317	1.669e-154	498.0	COG1171@1|root,arCOG01431@2157|Archaea,41SCU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD2_k127_448509_0	1459636.NTE_01274	1.616e-49	180.0	arCOG08745@1|root,arCOG08745@2157|Archaea,41SU1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_448509_1	1459636.NTE_00715	7.905e-33	129.0	COG2058@1|root,arCOG04287@2157|Archaea,41SP0@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl12	-	-	ko:K02869	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s
YYD2_k127_450335_0	589924.Ferp_1638	1.152e-67	242.0	COG2152@1|root,arCOG04084@2157|Archaea,2XZSX@28890|Euryarchaeota	28890|Euryarchaeota	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
YYD2_k127_450335_2	1459636.NTE_02861	1.349e-59	215.0	COG0574@1|root,arCOG01111@2157|Archaea,41SYV@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Pyruvate phosphate dikinase	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YYD2_k127_450335_1	436308.Nmar_0595	3.675e-60	226.0	COG1215@1|root,arCOG01389@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011,ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
YYD2_k127_450335_3	877455.Metbo_2457	5.935e-59	208.0	COG1839@1|root,arCOG04298@2157|Archaea,2XY40@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
YYD2_k127_4505680_0	1123020.AUIE01000036_gene2700	1.576e-16	85.0	COG3485@1|root,COG3485@2|Bacteria,1QEWY@1224|Proteobacteria,1TBU7@1236|Gammaproteobacteria,1YJ2I@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Dioxygenase	-	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C
YYD2_k127_4508882_0	1459636.NTE_02865	1.316e-15	78.0	arCOG10406@1|root,arCOG10406@2157|Archaea,41SVU@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger, C2H2 type	-	-	-	-	-	-	-	-	-	-	-	-	zf-C2H2
YYD2_k127_4515909_0	1459636.NTE_02481	9.548e-168	543.0	COG0034@1|root,COG0367@1|root,arCOG00071@2157|Archaea,arCOG00093@2157|Archaea	2157|Archaea	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	asnB	-	6.3.1.14,6.3.5.4	ko:K01953,ko:K06927	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578,R03613	RC00010,RC00358	ko00000,ko00001,ko01000,ko01002,ko03012	-	-	-	Asn_synthase,GATase_6,GATase_7
YYD2_k127_4515909_1	1459636.NTE_00844	5.531e-89	299.0	COG1335@1|root,arCOG01943@2157|Archaea	2157|Archaea	Q	COG1335 Amidases related to nicotinamidase	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
YYD2_k127_4519062_11	1459636.NTE_02466	1.608e-14	74.0	arCOG11612@1|root,arCOG11612@2157|Archaea,41T8D@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4519062_2	1459636.NTE_02468	2.845e-149	486.0	COG0621@1|root,arCOG01358@2157|Archaea,41SB9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	MiaB-like tRNA modifying enzyme	-	-	2.8.4.5	ko:K15865	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
YYD2_k127_4519062_5	1459636.NTE_01742	5.52e-120	391.0	COG2513@1|root,arCOG00581@2157|Archaea,41SEN@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
YYD2_k127_4519062_7	436308.Nmar_0257	9.69e-58	205.0	COG1695@1|root,arCOG00002@2157|Archaea,41SN8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD2_k127_4519062_10	1459636.NTE_02851	3.385e-19	94.0	arCOG10597@1|root,arCOG10597@2157|Archaea	2157|Archaea	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4519062_8	1459636.NTE_00823	1.203e-55	198.0	COG1259@1|root,arCOG01759@2157|Archaea,41SQI@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
YYD2_k127_4519062_9	1459636.NTE_00822	1.931e-38	156.0	arCOG08714@1|root,arCOG08714@2157|Archaea,41SPW@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4519062_3	1459636.NTE_01978	3.196e-142	461.0	COG3769@1|root,arCOG04158@2157|Archaea	2157|Archaea	S	Mannosyl-3-phosphoglycerate synthase	mngA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.217	ko:K05947	ko00051,map00051	-	R05768	RC00005,RC00397,RC02748	ko00000,ko00001,ko01000,ko01003	-	-	-	Osmo_MPGsynth
YYD2_k127_4519062_0	1459636.NTE_00800	0.0	1298.0	COG0480@1|root,arCOG01559@2157|Archaea,41S9B@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YYD2_k127_4519062_6	1459636.NTE_02318	3.28e-105	347.0	COG1378@1|root,arCOG02038@2157|Archaea,41SFR@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
YYD2_k127_4519062_1	1459636.NTE_01645	1.811e-155	497.0	COG1260@1|root,arCOG04213@2157|Archaea,41SEZ@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
YYD2_k127_4519062_4	1459636.NTE_00832	1.429e-126	422.0	arCOG08801@1|root,arCOG08801@2157|Archaea	2157|Archaea	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4520838_0	1459636.NTE_01128	5.52e-52	187.0	arCOG00516@1|root,arCOG00516@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
YYD2_k127_4527815_0	1459636.NTE_01491	9.564e-23	102.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4530234_3	237368.SCABRO_01742	1.761e-11	68.0	COG4095@1|root,COG4095@2|Bacteria,2J3PM@203682|Planctomycetes	203682|Planctomycetes	S	PQ loop repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4530234_2	1459636.NTE_00083	1.22e-26	115.0	arCOG04038@1|root,arCOG04038@2157|Archaea,41SQU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4530234_1	1459636.NTE_00035	7.963e-50	183.0	COG1846@1|root,arCOG03748@2157|Archaea,41T7R@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4530234_0	1459636.NTE_00059	1.278e-69	242.0	COG0475@1|root,arCOG01955@2157|Archaea,41SG1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
YYD2_k127_4530390_0	1079986.JH164839_gene4565	4.004e-113	374.0	COG3291@1|root,COG3291@2|Bacteria,2GKA0@201174|Actinobacteria	201174|Actinobacteria	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	DUF346,Peptidase_M43
YYD2_k127_4530390_2	1173024.KI912151_gene2020	2.15e-27	115.0	2E8HZ@1|root,332W1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4530390_1	591159.ACEZ01000202_gene2307	3.398e-48	184.0	COG2234@1|root,COG2234@2|Bacteria,2I9YF@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YYD2_k127_4530741_1	1131266.ARWQ01000001_gene1156	3.193e-07	53.0	COG0727@1|root,arCOG02579@2157|Archaea,41SH8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
YYD2_k127_4530741_0	1459636.NTE_01415	9.482e-203	648.0	COG1782@1|root,arCOG00543@2157|Archaea,41T05@651137|Thaumarchaeota	651137|Thaumarchaeota	S	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_7,Lactamase_B_6,RMMBL
YYD2_k127_45328_1	1128421.JAGA01000003_gene2828	1.491e-18	88.0	COG2843@1|root,COG2843@2|Bacteria,2NQMV@2323|unclassified Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
YYD2_k127_45328_0	1185876.BN8_03703	1.823e-20	100.0	COG1403@1|root,COG1403@2|Bacteria,4NW50@976|Bacteroidetes	976|Bacteroidetes	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
YYD2_k127_4542343_0	481448.Minf_0851	2.359e-108	363.0	2C6Q3@1|root,2Z7T4@2|Bacteria	2|Bacteria	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
YYD2_k127_4542343_3	1370122.JHXQ01000002_gene2851	2.357e-18	91.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4BCXZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase2,He_PIG,HemolysinCabind
YYD2_k127_4542343_4	436308.Nmar_0853	5.784e-13	74.0	COG0346@1|root,arCOG02708@2157|Archaea,41SU3@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
YYD2_k127_4542343_1	927677.ALVU02000001_gene2461	1.128e-85	293.0	COG0596@1|root,COG0596@2|Bacteria,1G6JI@1117|Cyanobacteria,1H5B0@1142|Synechocystis	1117|Cyanobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD2_k127_4543798_0	1229909.NSED_03460	2.059e-07	63.0	COG0517@1|root,arCOG00601@2157|Archaea	2157|Archaea	C	CBS domain	cbs1	-	-	-	-	-	-	-	-	-	-	-	CBS,Ribosomal_S30AE
YYD2_k127_4543798_1	647113.Metok_0495	0.0003054	53.0	COG1900@1|root,arCOG00620@2157|Archaea,2XVEU@28890|Euryarchaeota,23Q91@183939|Methanococci	183939|Methanococci	S	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HcyBio
YYD2_k127_4549230_2	1459636.NTE_02506	2.642e-38	150.0	arCOG01390@1|root,arCOG01390@2157|Archaea,41S7Q@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_4549230_1	1229909.NSED_06195	6.553e-47	177.0	COG2094@1|root,arCOG04295@2157|Archaea,41SME@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
YYD2_k127_4549230_0	1459636.NTE_02003	2.13e-62	218.0	COG0750@1|root,arCOG04064@2157|Archaea,41SW5@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
YYD2_k127_4552616_0	1114856.C496_19515	1.155e-11	73.0	COG3316@1|root,arCOG02134@2157|Archaea,2XUAY@28890|Euryarchaeota,23SGY@183963|Halobacteria	183963|Halobacteria	L	COG3316 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
YYD2_k127_457036_1	1459636.NTE_01959	3.285e-103	342.0	COG1465@1|root,arCOG04353@2157|Archaea,41S88@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis	aroB'	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
YYD2_k127_457036_0	1459636.NTE_01960	3.168e-123	399.0	COG1830@1|root,arCOG04044@2157|Archaea,41SCP@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	aroA'	-	2.2.1.10,4.1.2.13	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001	R01068,R01070,R02568,R08568	RC00438,RC00439,RC00721,RC02301	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
YYD2_k127_457036_2	387631.Asulf_01997	3.897e-62	222.0	COG0171@1|root,arCOG00069@2157|Archaea,2XT7M@28890|Euryarchaeota,24632@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
YYD2_k127_457036_3	1459636.NTE_02880	5.317e-13	70.0	COG0150@1|root,arCOG00639@2157|Archaea,41SEE@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YYD2_k127_4575340_0	395961.Cyan7425_3678	2.31e-10	64.0	2E3IT@1|root,32YH8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4582462_0	247490.KSU1_C0752	1.223e-61	222.0	COG1488@1|root,COG1488@2|Bacteria,2IXDA@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
YYD2_k127_4582462_1	671065.MetMK1DRAFT_00008850	1.261e-52	192.0	COG1335@1|root,arCOG01943@2157|Archaea,2XQK1@28889|Crenarchaeota	28889|Crenarchaeota	Q	PFAM Isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
YYD2_k127_45887_1	1459636.NTE_01028	1.461e-63	223.0	COG0125@1|root,arCOG01891@2157|Archaea,41T33@651137|Thaumarchaeota	651137|Thaumarchaeota	F	thymidylate kinase	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
YYD2_k127_45887_0	1459636.NTE_01715	1.294e-67	239.0	COG0500@1|root,arCOG01783@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YYD2_k127_4615658_1	1459636.NTE_01562	7.792e-75	260.0	COG0457@1|root,arCOG03032@2157|Archaea	2157|Archaea	T	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_8
YYD2_k127_4615658_0	1459636.NTE_00439	8.814e-76	257.0	COG2131@1|root,arCOG01487@2157|Archaea,41SHS@651137|Thaumarchaeota	651137|Thaumarchaeota	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
YYD2_k127_46222_1	1026882.MAMP_02736	3.648e-09	64.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,460U8@72273|Thiotrichales	72273|Thiotrichales	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,He_PIG,HemolysinCabind
YYD2_k127_46222_0	1459636.NTE_03297	4.109e-162	522.0	COG0513@1|root,arCOG00558@2157|Archaea,41SM1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
YYD2_k127_4627915_3	1459636.NTE_02180	1.797e-66	229.0	COG1830@1|root,arCOG04044@2157|Archaea,41S64@651137|Thaumarchaeota	651137|Thaumarchaeota	E	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
YYD2_k127_4627915_0	1459636.NTE_02178	2.118e-316	974.0	COG0028@1|root,arCOG01998@2157|Archaea,41S63@651137|Thaumarchaeota	651137|Thaumarchaeota	E	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YYD2_k127_4627915_2	1459636.NTE_02177	1.929e-70	243.0	COG0440@1|root,arCOG04445@2157|Archaea,41SNS@651137|Thaumarchaeota	651137|Thaumarchaeota	E	acetolactate synthase, small	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
YYD2_k127_4627915_1	1459636.NTE_02176	1.248e-253	791.0	COG0119@1|root,arCOG02092@2157|Archaea,41SBX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
YYD2_k127_4638600_0	1459636.NTE_00331	8.996e-104	348.0	COG0517@1|root,arCOG00607@2157|Archaea	2157|Archaea	M	Belongs to the peptidase M50B family	-	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
YYD2_k127_4663892_0	1459636.NTE_03484	1.625e-184	584.0	COG0475@1|root,arCOG01953@2157|Archaea,41T00@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YYD2_k127_4663892_1	1459636.NTE_00325	4.537e-23	104.0	COG2149@1|root,arCOG05380@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
YYD2_k127_466506_0	357809.Cphy_0963	3.624e-14	77.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_466506_1	1155718.KB891951_gene4503	6.355e-07	52.0	COG3467@1|root,COG3467@2|Bacteria,2IFRI@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
YYD2_k127_4672851_0	1459636.NTE_00791	6.936e-86	301.0	COG0154@1|root,arCOG01717@2157|Archaea,41SCW@651137|Thaumarchaeota	2157|Archaea	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD2_k127_4677136_1	1459636.NTE_02806	1.292e-09	61.0	arCOG10404@1|root,arCOG10404@2157|Archaea	1459636.NTE_02806|-	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4680336_0	877455.Metbo_0232	1.303e-110	371.0	COG0068@1|root,arCOG01187@2157|Archaea,2XTHZ@28890|Euryarchaeota,23NPD@183925|Methanobacteria	183925|Methanobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
YYD2_k127_4680336_1	1459636.NTE_00889	2.735e-82	281.0	COG1064@1|root,arCOG01455@2157|Archaea,41SA9@651137|Thaumarchaeota	2157|Archaea	C	PFAM Alcohol dehydrogenase GroES-like domain	adh4	-	1.1.1.1	ko:K00001,ko:K13953,ko:K18382	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703	RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_4688248_0	589924.Ferp_2110	1.849e-229	734.0	COG0574@1|root,arCOG01111@2157|Archaea,2XU2T@28890|Euryarchaeota,245QA@183980|Archaeoglobi	183980|Archaeoglobi	G	PFAM Pyruvate phosphate dikinase, PEP	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YYD2_k127_4688248_2	237368.SCABRO_02487	2.383e-45	173.0	COG3259@1|root,COG3259@2|Bacteria,2IYS2@203682|Planctomycetes	203682|Planctomycetes	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
YYD2_k127_4688248_5	186497.PF1332	7.929e-14	75.0	COG0374@1|root,arCOG01549@2157|Archaea,2XTHE@28890|Euryarchaeota,24363@183968|Thermococci	183968|Thermococci	C	Nickel-dependent hydrogenase	-	-	1.12.1.3,1.12.1.5	ko:K17993	ko00920,map00920	-	R10390	-	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
YYD2_k127_4688248_6	552811.Dehly_0929	1.811e-11	66.0	COG3259@1|root,COG3259@2|Bacteria,2G68W@200795|Chloroflexi,34CQT@301297|Dehalococcoidia	2|Bacteria	C	hydrogenase large subunit	hoxH	-	1.12.1.2,1.8.98.5	ko:K00436,ko:K14126	ko00680,map00680	-	R00019,R00700,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
YYD2_k127_4688248_4	517417.Cpar_0318	5.796e-18	89.0	COG1941@1|root,COG1941@2|Bacteria,1FDE2@1090|Chlorobi	1090|Chlorobi	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
YYD2_k127_4688248_1	399549.Msed_0933	3.728e-119	392.0	COG0309@1|root,arCOG00636@2157|Archaea,2XPSN@28889|Crenarchaeota	28889|Crenarchaeota	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
YYD2_k127_4688248_3	399549.Msed_0929	2.106e-43	166.0	COG0235@1|root,arCOG04226@2157|Archaea,2XR76@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM class II aldolase adducin family protein	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
YYD2_k127_4688895_1	1459636.NTE_02166	1.355e-26	113.0	arCOG11431@1|root,arCOG11431@2157|Archaea,41T8G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4688895_0	1094980.Mpsy_0997	2.339e-51	205.0	COG0683@1|root,arCOG01021@2157|Archaea,2Y6Q1@28890|Euryarchaeota,2NAW8@224756|Methanomicrobia	224756|Methanomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YYD2_k127_4690840_0	525904.Tter_0425	2.423e-111	370.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD2_k127_4690840_1	436308.Nmar_1087	3.528e-06	56.0	arCOG08812@1|root,arCOG08812@2157|Archaea	436308.Nmar_1087|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4691253_1	1173023.KE650771_gene4286	1.643e-17	89.0	COG0515@1|root,COG0515@2|Bacteria,1GCAZ@1117|Cyanobacteria,1JMUY@1189|Stigonemataceae	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD2_k127_4691253_0	360104.CCC13826_0158	1.898e-60	217.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions	1224|Proteobacteria	F	PFAM Creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
YYD2_k127_4691852_0	1459636.NTE_00092	1.176e-91	310.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	1459636.NTE_00092|-	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	-
YYD2_k127_4691852_2	1459636.NTE_00408	3.512e-22	100.0	arCOG08700@1|root,arCOG08700@2157|Archaea,41SV2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4691852_1	1459636.NTE_01409	2.204e-91	310.0	COG3276@1|root,arCOG01564@2157|Archaea,41SCR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	elongation factor Tu	-	-	-	-	-	-	-	-	-	-	-	-	GTP_EFTU_D2
YYD2_k127_4692154_4	1459636.NTE_02600	9.665e-81	275.0	COG1701@1|root,arCOG04262@2157|Archaea,41SXP@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pfam:DUF137	-	-	6.3.2.36	ko:K09722	ko00410,ko00770,ko01100,map00410,map00770,map01100	-	R09379	RC00096,RC00141	ko00000,ko00001,ko01000	-	-	-	PPS_PS
YYD2_k127_4692154_3	1459636.NTE_02599	5.482e-86	296.0	COG1829@1|root,arCOG04263@2157|Archaea,41T1V@651137|Thaumarchaeota	651137|Thaumarchaeota	S	kinase, sugar kinase superfamily	-	-	2.7.1.169	ko:K06982	ko00770,ko01100,map00770,map01100	-	R09378	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_N
YYD2_k127_4692154_6	1459636.NTE_00016	2.159e-47	180.0	COG1058@1|root,arCOG00215@2157|Archaea	2157|Archaea	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	cinA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
YYD2_k127_4692154_0	1459636.NTE_00773	1.643e-269	852.0	COG3889@1|root,arCOG10597@1|root,arCOG01672@2157|Archaea,arCOG10597@2157|Archaea,41SA5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YYD2_k127_4692154_1	1459636.NTE_01473	2.919e-185	580.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
YYD2_k127_4692154_5	1459636.NTE_01470	1.024e-53	190.0	COG0023@1|root,arCOG04223@2157|Archaea,41SNU@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the SUI1 family	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
YYD2_k127_4692154_7	1459636.NTE_01468	1.786e-20	91.0	COG4023@1|root,arCOG02957@2157|Archaea,41SUS@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Sec61beta family	-	-	-	-	-	-	-	-	-	-	-	-	Sec61_beta
YYD2_k127_4692154_2	1459636.NTE_01467	8.746e-144	476.0	COG3356@1|root,arCOG04351@2157|Archaea,41S7S@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Predicted membrane protein (DUF2070)	-	-	-	ko:K08979	-	-	-	-	ko00000	-	-	-	DUF2070
YYD2_k127_4692154_9	859653.HIMB5_00010900	0.000842	46.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_21
YYD2_k127_4692154_8	243090.RB2498	2.118e-09	61.0	COG2242@1|root,COG2242@2|Bacteria,2J0UY@203682|Planctomycetes	203682|Planctomycetes	H	TIGRFAM methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
YYD2_k127_4695198_1	1229909.NSED_06995	0.0009976	49.0	COG4250@1|root,arCOG02910@2157|Archaea	2157|Archaea	T	Sensory domain in DIguanylate Cyclases and Two-component system	-	-	-	-	-	-	-	-	-	-	-	-	DICT
YYD2_k127_4695198_0	1459636.NTE_01962	3.059e-10	65.0	arCOG08680@1|root,arCOG08680@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4713123_0	1459636.NTE_03327	1.423e-79	269.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4713123_1	675813.VIB_002676	2.396e-05	52.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,1S3RT@1236|Gammaproteobacteria,1XX1H@135623|Vibrionales	135623|Vibrionales	S	TQO small subunit DoxD	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
YYD2_k127_4718708_2	1459636.NTE_02680	3.189e-08	58.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_4718708_0	1459636.NTE_02704	4.504e-22	96.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4718708_1	1459636.NTE_00236	2.337e-16	84.0	arCOG09752@1|root,arCOG09752@2157|Archaea,41T9M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4718708_3	449447.MAE_59770	0.0002045	50.0	COG2044@1|root,COG2044@2|Bacteria,1GQSP@1117|Cyanobacteria	1117|Cyanobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
YYD2_k127_4722844_0	1459636.NTE_00367	5.223e-10	67.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_00367|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4722844_1	457412.RSAG_01961	1.303e-05	50.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UYPX@1239|Firmicutes,24BA6@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
YYD2_k127_4730830_0	1459636.NTE_01508	1.537e-14	78.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4730830_1	543526.Htur_1678	0.0008767	48.0	arCOG11838@1|root,arCOG11838@2157|Archaea,2Y03W@28890|Euryarchaeota,23XVJ@183963|Halobacteria	183963|Halobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
YYD2_k127_4733862_0	1459636.NTE_01932	4.428e-48	182.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
YYD2_k127_4733862_1	883.DvMF_0393	5.791e-41	158.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7Z@28221|Deltaproteobacteria,2M8HE@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
YYD2_k127_4734337_0	1459636.NTE_01052	2.638e-109	383.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_4739505_0	1459636.NTE_03525	2.647e-50	183.0	COG3794@1|root,arCOG02926@2157|Archaea,41SPG@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Copper binding proteins, plastocyanin azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
YYD2_k127_4739505_1	1459636.NTE_01575	7.311e-37	142.0	arCOG08633@1|root,arCOG08633@2157|Archaea,41SUK@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4739505_2	1459636.NTE_01277	4.821e-14	72.0	COG1522@1|root,arCOG01580@2157|Archaea,41SJD@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
YYD2_k127_4759643_2	1459636.NTE_00433	3.403e-74	253.0	arCOG08765@1|root,arCOG08765@2157|Archaea,41SQJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4759643_1	1459636.NTE_01048	5.585e-192	609.0	COG0624@1|root,arCOG01110@2157|Archaea,41SAE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YYD2_k127_4759643_0	1459636.NTE_01051	9.872e-313	972.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,41S6N@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K18593	ko00720,ko01120,map00720,map01120	-	R10758	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
YYD2_k127_4759643_3	1459636.NTE_01054	2.615e-16	82.0	arCOG08023@1|root,arCOG08023@2157|Archaea,41SKK@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
YYD2_k127_4766317_0	1459636.NTE_00367	5.417e-14	76.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_00367|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4773057_0	693661.Arcve_0993	1.016e-104	355.0	COG0383@1|root,arCOG03661@2157|Archaea,2XVNX@28890|Euryarchaeota	28890|Euryarchaeota	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
YYD2_k127_4778108_1	1459636.NTE_02412	1.34e-14	76.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_4778108_0	1459636.NTE_01650	2.703e-33	132.0	COG1581@1|root,arCOG01753@2157|Archaea	2157|Archaea	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
YYD2_k127_477867_3	1459636.NTE_02601	9.899e-104	345.0	COG0413@1|root,arCOG00584@2157|Archaea,41SZX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
YYD2_k127_477867_1	1459636.NTE_02602	3.324e-125	414.0	COG0452@1|root,arCOG01704@2157|Archaea,41SYG@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
YYD2_k127_477867_2	1459636.NTE_02604	1.513e-114	380.0	COG0006@1|root,arCOG01000@2157|Archaea,41T14@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the peptidase M24B family	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
YYD2_k127_477867_0	1459636.NTE_02607	2.73e-196	616.0	COG0075@1|root,arCOG00082@2157|Archaea,41SZZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YYD2_k127_477867_4	1459636.NTE_02621	2.189e-30	121.0	COG1047@1|root,arCOG00980@2157|Archaea,41T0T@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
YYD2_k127_4779713_2	273116.14324688	1.378e-07	54.0	COG1801@1|root,arCOG04291@2157|Archaea,2XY6C@28890|Euryarchaeota,2425U@183967|Thermoplasmata	183967|Thermoplasmata	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD2_k127_4779713_1	1459636.NTE_01872	1.206e-25	108.0	COG1801@1|root,arCOG04291@2157|Archaea	2157|Archaea	L	DUF72 domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD2_k127_4784743_4	1459636.NTE_02041	1.305e-107	352.0	COG1208@1|root,arCOG00663@2157|Archaea,41SGT@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YYD2_k127_4784743_3	1459636.NTE_02040	3.232e-112	377.0	COG0351@1|root,COG1992@1|root,arCOG00020@2157|Archaea,arCOG00021@2157|Archaea,41SA1@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Phosphomethylpyrimidine kinase	-	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K21219	ko00730,ko01100,map00730,map01100	-	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin,ThiP_synth
YYD2_k127_4784743_7	1459636.NTE_01934	1.428e-35	138.0	COG1436@1|root,arCOG04102@2157|Archaea,41T76@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP synthase (F/14-kDa) subunit	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
YYD2_k127_4784743_6	1459636.NTE_01942	2.918e-38	147.0	COG0484@1|root,arCOG02846@2157|Archaea,41T68@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
YYD2_k127_4784743_2	1459636.NTE_02261	4.07e-148	478.0	COG0457@1|root,arCOG03032@2157|Archaea,41SBD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
YYD2_k127_4784743_1	1459636.NTE_02257	9.048e-152	481.0	COG1635@1|root,arCOG00574@2157|Archaea,41SDJ@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur	thi4	-	-	ko:K03146	ko00730,ko01100,map00730,map01100	-	R10685	RC00033,RC03253,RC03254	ko00000,ko00001	-	-	-	Thi4
YYD2_k127_4784743_5	1459636.NTE_02241	3.614e-44	172.0	arCOG04668@1|root,arCOG04668@2157|Archaea,41SMD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4784743_0	1459636.NTE_02240	6.063e-154	492.0	COG0492@1|root,arCOG01296@2157|Archaea,41S97@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YYD2_k127_4798013_0	1459636.NTE_01418	1.608e-116	392.0	COG0072@1|root,arCOG00412@2157|Archaea,41S8M@651137|Thaumarchaeota	651137|Thaumarchaeota	J	phenylalanyl-tRNA synthetase, beta subunit	-	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5
YYD2_k127_4801126_0	1459636.NTE_00019	1.988e-160	515.0	COG0527@1|root,arCOG00861@2157|Archaea,41SFK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
YYD2_k127_4801126_1	1459636.NTE_00018	6.952e-122	397.0	COG0115@1|root,arCOG02297@2157|Archaea,41SD5@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YYD2_k127_4801126_2	1459636.NTE_01512	7.309e-25	109.0	COG2236@1|root,arCOG00040@2157|Archaea,41TA1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	phosphoribosyltransferase	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	-
YYD2_k127_4812960_0	1229909.NSED_08905	9.959e-12	67.0	arCOG02240@1|root,arCOG02240@2157|Archaea,41SSM@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
YYD2_k127_4821673_0	1459636.NTE_00597	7.452e-64	224.0	COG3945@1|root,arCOG01471@2157|Archaea,41T45@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YYD2_k127_4822516_1	1459636.NTE_02127	2.183e-70	248.0	COG2047@1|root,arCOG00348@2157|Archaea	2157|Archaea	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
YYD2_k127_4822516_0	1459636.NTE_02639	1.402e-90	306.0	COG0063@1|root,arCOG00018@2157|Archaea,41S8I@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase
YYD2_k127_482381_2	1459636.NTE_02306	1.589e-19	88.0	COG0115@1|root,arCOG02297@2157|Archaea,41S5T@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YYD2_k127_482381_0	1459636.NTE_02305	2.514e-65	229.0	COG1056@1|root,arCOG00972@2157|Archaea,41SHQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Nicotinamide-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_482381_1	1459636.NTE_02304	7.381e-41	152.0	COG1581@1|root,arCOG01753@2157|Archaea,41SQ4@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	-	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
YYD2_k127_4842854_1	436308.Nmar_0482	4.053e-12	68.0	COG0581@1|root,arCOG00168@2157|Archaea,41SZ4@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM phosphate ABC transporter	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YYD2_k127_4842854_0	1459636.NTE_00045	4.622e-124	406.0	COG0573@1|root,arCOG00167@2157|Archaea,41SYE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YYD2_k127_4846697_0	1459636.NTE_00005	1.827e-11	72.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4848643_0	1459636.NTE_01122	1.717e-31	126.0	COG0783@1|root,arCOG01101@2157|Archaea	2157|Archaea	P	Belongs to the Dps family	frt	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
YYD2_k127_4849345_0	1459636.NTE_02717	3.122e-66	239.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	fgd-2	-	1.1.98.2,1.1.98.5	ko:K15510,ko:K21835	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
YYD2_k127_4849345_1	1459636.NTE_02155	3.007e-14	74.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_4849345_2	1158345.JNLL01000001_gene1296	3.401e-05	48.0	COG0210@1|root,COG1112@1|root,COG0210@2|Bacteria,COG1112@2|Bacteria,2G3TJ@200783|Aquificae	200783|Aquificae	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
YYD2_k127_4850563_0	1459636.NTE_01727	4.003e-81	278.0	COG1028@1|root,arCOG01259@2157|Archaea,41SXY@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YYD2_k127_4850563_1	1459636.NTE_01614	1.374e-45	173.0	COG1241@1|root,arCOG00439@2157|Archaea	2157|Archaea	L	Belongs to the MCM family	-	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	MCM,MCM_OB
YYD2_k127_4855687_7	1459636.NTE_02729	2.006e-10	66.0	COG0347@1|root,arCOG02305@2157|Archaea,41TB5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
YYD2_k127_4855687_2	1459636.NTE_02404	1.777e-109	363.0	COG0608@1|root,arCOG00424@2157|Archaea,41SE2@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
YYD2_k127_4855687_1	1459636.NTE_00119	1.732e-116	376.0	COG2406@1|root,arCOG01093@2157|Archaea,41S6X@651137|Thaumarchaeota	2157|Archaea	S	Ferritin-like domain	dps	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
YYD2_k127_4855687_4	1459636.NTE_03124	1.791e-82	286.0	COG0524@1|root,arCOG00014@2157|Archaea	2157|Archaea	G	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB,Regulator_TrmB,TrmB
YYD2_k127_4855687_5	589924.Ferp_2384	7.71e-65	231.0	COG1004@1|root,arCOG00253@2157|Archaea,2XTQY@28890|Euryarchaeota,246SR@183980|Archaeoglobi	183980|Archaeoglobi	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YYD2_k127_4855687_3	1128421.JAGA01000003_gene3109	7.294e-95	328.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.212	ko:K00752	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
YYD2_k127_4855687_6	1459636.NTE_00679	6.433e-21	93.0	arCOG05330@1|root,arCOG05330@2157|Archaea,41SUC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4855687_0	1459636.NTE_00680	6.959e-185	587.0	COG0441@1|root,arCOG00401@2157|Archaea,41S9K@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-Thr_ED,tRNA-synt_2b
YYD2_k127_4858136_4	1459636.NTE_01107	1.636e-59	208.0	COG0346@1|root,arCOG02706@2157|Archaea,41SQS@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
YYD2_k127_4858136_1	1459636.NTE_02175	7.758e-151	483.0	COG0473@1|root,arCOG01163@2157|Archaea,41SAA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YYD2_k127_4858136_0	1459636.NTE_01108	7.548e-266	826.0	COG1884@1|root,arCOG04232@2157|Archaea,41SBW@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
YYD2_k127_4858136_2	1459636.NTE_01109	3.418e-123	403.0	COG1703@1|root,arCOG01226@2157|Archaea,41SFN@651137|Thaumarchaeota	651137|Thaumarchaeota	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
YYD2_k127_4858136_3	1459636.NTE_01111	1.273e-63	220.0	COG2185@1|root,arCOG01710@2157|Archaea,41SJN@651137|Thaumarchaeota	651137|Thaumarchaeota	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
YYD2_k127_4859037_0	1459636.NTE_02840	9.61e-144	464.0	COG1759@1|root,arCOG04346@2157|Archaea,41SBR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
YYD2_k127_4859037_2	1459636.NTE_00828	3.934e-58	206.0	arCOG04006@1|root,arCOG04006@2157|Archaea,41SKF@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PBS lyase HEAT-like repeat	-	-	1.14.99.29	ko:K06072	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2
YYD2_k127_4859037_1	1459636.NTE_00827	5.464e-62	216.0	arCOG08712@1|root,arCOG08712@2157|Archaea,41SU6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4859037_3	1459636.NTE_00195	2.218e-25	110.0	COG0745@1|root,arCOG02595@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	ko:K07668,ko:K07669	ko02020,map02020	M00459,M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
YYD2_k127_4865638_4	1459636.NTE_01817	1.83e-50	181.0	arCOG11395@1|root,arCOG11395@2157|Archaea,41TBH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4865638_6	1131266.ARWQ01000002_gene541	0.0001911	49.0	COG1545@1|root,arCOG01285@2157|Archaea	2157|Archaea	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
YYD2_k127_4865638_1	1459636.NTE_01815	3.923e-103	347.0	COG0183@1|root,arCOG01278@2157|Archaea,41SB7@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
YYD2_k127_4865638_0	1459636.NTE_01814	1.05e-111	370.0	COG2141@1|root,arCOG02410@2157|Archaea,41SC0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
YYD2_k127_4865638_2	1459636.NTE_01813	7.928e-96	319.0	COG1208@1|root,arCOG00663@2157|Archaea,41SIU@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
YYD2_k127_4865638_3	1459636.NTE_01821	8.668e-66	229.0	COG0097@1|root,arCOG04090@2157|Archaea,41SJG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rpl6	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
YYD2_k127_4865638_5	1459636.NTE_01822	6.709e-21	91.0	COG0096@1|root,arCOG04091@2157|Archaea,41SMM@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rps8	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
YYD2_k127_4866192_1	443144.GM21_2393	2.44e-07	61.0	2E3IT@1|root,32YH8@2|Bacteria,1N8T8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4866192_0	1459636.NTE_02854	7.168e-92	308.0	COG0614@1|root,arCOG04233@2157|Archaea,41SXD@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
YYD2_k127_4878909_1	1459636.NTE_01970	1.651e-149	481.0	COG0667@1|root,arCOG01623@2157|Archaea,41SA6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD2_k127_4878909_0	1459636.NTE_02293	9.55e-240	754.0	COG1855@1|root,arCOG04116@2157|Archaea,41SX0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Large family of predicted nucleotide-binding domains	-	-	-	ko:K06865	-	-	-	-	ko00000	-	-	-	KH_1,T2SSE
YYD2_k127_4878909_2	1459636.NTE_03210	1.401e-89	302.0	COG0077@1|root,arCOG00255@2157|Archaea,41SA8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Prephenate dehydratase	-	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
YYD2_k127_4878909_7	1459636.NTE_03211	5.522e-22	101.0	arCOG08827@1|root,arCOG08827@2157|Archaea,41SUW@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4878909_5	1459636.NTE_00032	3.095e-39	150.0	COG0803@1|root,arCOG01005@2157|Archaea,41T29@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
YYD2_k127_4878909_6	596315.HMPREF0634_1210	2.233e-30	126.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,25R39@186804|Peptostreptococcaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
YYD2_k127_4878909_3	1459636.NTE_02375	9.498e-79	270.0	COG0084@1|root,arCOG00891@2157|Archaea,41SGP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YYD2_k127_4878909_4	483219.LILAB_06120	3.985e-54	200.0	COG1409@1|root,COG1409@2|Bacteria,1MX4X@1224|Proteobacteria	1224|Proteobacteria	N	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
YYD2_k127_4880395_1	1229909.NSED_07865	2.999e-08	59.0	arCOG08678@1|root,arCOG08678@2157|Archaea,41TA6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4880395_0	1459636.NTE_01338	1.05e-95	317.0	COG0202@1|root,arCOG04241@2157|Archaea,41SK0@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-directed RNA polymerase, alpha subunit 40 kD subunit	-	-	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_A_bac,RNA_pol_L
YYD2_k127_4881344_3	1156937.MFUM_280004	2.155e-33	137.0	COG2843@1|root,COG2843@2|Bacteria,46W53@74201|Verrucomicrobia,37H7T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
YYD2_k127_4881344_5	1459636.NTE_00203	4.525e-14	77.0	COG2132@1|root,COG3794@1|root,arCOG02926@2157|Archaea,arCOG03914@2157|Archaea,41SY3@651137|Thaumarchaeota	651137|Thaumarchaeota	CQ	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
YYD2_k127_4881344_6	237368.SCABRO_01742	1.476e-13	73.0	COG4095@1|root,COG4095@2|Bacteria,2J3PM@203682|Planctomycetes	203682|Planctomycetes	S	PQ loop repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4881344_2	1459636.NTE_02476	1.85e-119	390.0	COG2086@1|root,arCOG00446@2157|Archaea,41SX2@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
YYD2_k127_4881344_1	1131266.ARWQ01000002_gene513	1.112e-156	504.0	COG2025@1|root,arCOG00448@2157|Archaea,41SZJ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
YYD2_k127_4881344_0	1131266.ARWQ01000002_gene512	1.476e-254	798.0	COG0644@1|root,COG2440@1|root,arCOG00570@2157|Archaea,arCOG01984@2157|Archaea,41SXJ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	-
YYD2_k127_4884106_2	1459636.NTE_02855	4.454e-55	193.0	COG0051@1|root,arCOG01758@2157|Archaea,41SQB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Involved in the binding of tRNA to the ribosomes	rps10	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
YYD2_k127_4884106_1	1459636.NTE_02856	4.237e-239	743.0	COG5256@1|root,arCOG01561@2157|Archaea,41SD2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K03231	ko03013,ko05134,map03013,map05134	-	-	-	ko00000,ko00001,ko03012,ko03016,ko03019,ko04131,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YYD2_k127_4884106_4	1173263.Syn7502_01281	9.194e-25	106.0	COG2154@1|root,COG2154@2|Bacteria,1G7P9@1117|Cyanobacteria,1H11A@1129|Synechococcus	1117|Cyanobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YYD2_k127_4884106_0	1459636.NTE_00424	9.448e-247	768.0	COG0174@1|root,arCOG01909@2157|Archaea,41SD6@651137|Thaumarchaeota	651137|Thaumarchaeota	E	TIGRFAM glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YYD2_k127_4884106_3	1459636.NTE_00425	1.932e-35	141.0	COG1711@1|root,arCOG00551@2157|Archaea,41SVQ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	protein conserved in archaea	-	-	-	ko:K09723	-	-	-	-	ko00000,ko03032	-	-	-	-
YYD2_k127_4884911_0	436308.Nmar_1456	3.59e-15	81.0	arCOG08670@1|root,arCOG08728@1|root,arCOG08670@2157|Archaea,arCOG08728@2157|Archaea	436308.Nmar_1456|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4886111_0	1459636.NTE_00825	7.317e-22	98.0	COG1826@1|root,arCOG02694@2157|Archaea,41T8C@651137|Thaumarchaeota	651137|Thaumarchaeota	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
YYD2_k127_4887944_0	1459636.NTE_00046	5.925e-136	441.0	COG0226@1|root,arCOG08033@1|root,arCOG00213@2157|Archaea,arCOG08033@2157|Archaea,41SXU@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM phosphate ABC transporter	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
YYD2_k127_4890927_0	1459636.NTE_00430	2.528e-111	364.0	COG4221@1|root,arCOG01265@2157|Archaea,41S66@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YYD2_k127_4891445_0	926549.KI421517_gene674	3.412e-41	157.0	COG2133@1|root,COG2133@2|Bacteria,4NFN2@976|Bacteroidetes,47MU4@768503|Cytophagia	976|Bacteroidetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD2_k127_4892017_0	1459636.NTE_00680	4.127e-91	303.0	COG0441@1|root,arCOG00401@2157|Archaea,41S9K@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-Thr_ED,tRNA-synt_2b
YYD2_k127_4892941_2	1459636.NTE_03092	9.151e-37	141.0	COG3408@1|root,arCOG03287@2157|Archaea	2157|Archaea	G	Glycogen debranching enzyme	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	GDE_C,GDE_N_bis,Trehalase
YYD2_k127_4892941_0	1459636.NTE_00138	5.241e-100	334.0	COG0463@1|root,arCOG00894@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_4892941_1	1459636.NTE_00139	1.043e-83	294.0	COG0438@1|root,arCOG04796@2157|Archaea,41T9D@651137|Thaumarchaeota	2157|Archaea	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YYD2_k127_4895358_1	224325.AF_0847	3.59e-15	81.0	COG0517@1|root,arCOG00606@2157|Archaea,2XX11@28890|Euryarchaeota,24692@183980|Archaeoglobi	183980|Archaeoglobi	S	signal transduction protein with CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YYD2_k127_4895358_0	1459636.NTE_00881	3.542e-36	142.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD2_k127_4895358_2	1178537.BA1_04130	4.781e-08	54.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus	91061|Bacilli	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapB	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016491,GO:0016620,GO:0016903,GO:0019318,GO:0019319,GO:0036094,GO:0043891,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
YYD2_k127_4896905_6	1459636.NTE_01238	1.989e-34	132.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01238|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4896905_3	1459636.NTE_02804	5.455e-56	201.0	COG2096@1|root,arCOG00489@2157|Archaea,41T2I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
YYD2_k127_4896905_5	1459636.NTE_02807	1.559e-39	153.0	COG1896@1|root,arCOG04311@2157|Archaea,41SQE@651137|Thaumarchaeota	651137|Thaumarchaeota	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
YYD2_k127_4896905_4	1459636.NTE_02808	1.512e-41	156.0	arCOG08655@1|root,arCOG08655@2157|Archaea,41SR9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4896905_0	1459636.NTE_02809	1.257e-195	617.0	COG1915@1|root,arCOG04422@2157|Archaea,41SBQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	LOR SDH bifunctional	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
YYD2_k127_4896905_1	1459636.NTE_02817	4.874e-187	595.0	COG0064@1|root,arCOG01718@2157|Archaea,41S9S@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YYD2_k127_4896905_2	1459636.NTE_02818	4.047e-177	565.0	COG0154@1|root,arCOG01717@2157|Archaea,41SCW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD2_k127_4903628_0	1459636.NTE_01425	8.505e-187	594.0	COG0028@1|root,arCOG01999@2157|Archaea	2157|Archaea	C	Belongs to the TPP enzyme family	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	Rubredoxin,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YYD2_k127_4904976_0	1459636.NTE_03330	1.73e-77	265.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	2157|Archaea	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YYD2_k127_4904976_4	582744.Msip34_0280	1.303e-05	50.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,2KKS5@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Belongs to the peptidase S1C family	-	-	-	ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
YYD2_k127_4904976_1	1459636.NTE_03333	1.793e-24	112.0	COG1733@1|root,arCOG01057@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
YYD2_k127_4904976_3	436308.Nmar_1661	2.095e-06	50.0	COG1733@1|root,arCOG01057@2157|Archaea,41T7C@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
YYD2_k127_4904976_2	273116.14325504	1.52e-09	60.0	COG5466@1|root,arCOG05278@2157|Archaea,2Y5U3@28890|Euryarchaeota,242H8@183967|Thermoplasmata	183967|Thermoplasmata	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
YYD2_k127_49121_1	1459636.NTE_00066	1.442e-78	269.0	COG2047@1|root,arCOG00348@2157|Archaea	2157|Archaea	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
YYD2_k127_49121_0	1459636.NTE_00067	1.122e-98	326.0	COG2241@1|root,arCOG00650@2157|Archaea,41SGN@651137|Thaumarchaeota	651137|Thaumarchaeota	H	TIGRFAM precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit	-	-	2.1.1.289	ko:K03399	ko00860,ko01100,map00860,map01100	-	R05813,R07775	RC00003,RC02052,RC02053	ko00000,ko00001,ko01000	-	-	-	TP_methylase
YYD2_k127_4916738_0	1459636.NTE_02181	7.973e-134	435.0	COG1063@1|root,arCOG01459@2157|Archaea,41S98@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_4920539_8	1313421.JHBV01000003_gene619	2.033e-13	72.0	COG3485@1|root,COG3485@2|Bacteria,4NN13@976|Bacteroidetes,1IZE6@117747|Sphingobacteriia	976|Bacteroidetes	Q	Dioxygenase	-	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C
YYD2_k127_4920539_7	1380763.BG53_14400	1.732e-22	108.0	COG1226@1|root,COG1226@2|Bacteria,1V285@1239|Firmicutes,4I17E@91061|Bacilli	91061|Bacilli	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2
YYD2_k127_4920539_9	1459636.NTE_01962	2.268e-11	68.0	arCOG08680@1|root,arCOG08680@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4920539_4	1459636.NTE_03129	1.059e-72	256.0	COG0412@1|root,arCOG01659@2157|Archaea,41T1E@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Chlorophyllase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
YYD2_k127_4920539_6	1459636.NTE_02916	4.215e-31	126.0	COG3485@1|root,2N56G@2157|Archaea	2157|Archaea	Q	Protocatechuate 3,4-dioxygenase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
YYD2_k127_4920539_2	1184267.A11Q_698	8.609e-111	365.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2MTIH@213481|Bdellovibrionales,2WIJQ@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
YYD2_k127_4920539_3	1304880.JAGB01000003_gene1298	3.549e-96	326.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YYD2_k127_4920539_5	373903.Hore_23430	5.059e-36	140.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,24N5H@186801|Clostridia,3WBXB@53433|Halanaerobiales	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
YYD2_k127_4920539_1	1379698.RBG1_1C00001G1499	4.4e-115	384.0	COG0403@1|root,COG0403@2|Bacteria,2NNP1@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204	1.4.4.2	ko:K00281,ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
YYD2_k127_4920539_0	1209989.TepiRe1_0386	2.094e-167	540.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia,42FHX@68295|Thermoanaerobacterales	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
YYD2_k127_4920539_10	1163730.FFONT_1312	8.401e-09	60.0	COG0095@1|root,arCOG03837@2157|Archaea,2XRCT@28889|Crenarchaeota	28889|Crenarchaeota	H	Bacterial lipoate protein ligase C-terminus	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	Lip_prot_lig_C
YYD2_k127_4920539_11	443144.GM21_0393	6.724e-08	56.0	COG0095@1|root,COG0095@2|Bacteria,1RI3T@1224|Proteobacteria,42SQP@68525|delta/epsilon subdivisions,2WQH2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM biotin lipoate A B protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YYD2_k127_4924600_0	1459636.NTE_01754	9.092e-66	237.0	COG0608@1|root,arCOG00427@2157|Archaea,41SZF@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
YYD2_k127_4924600_1	1459636.NTE_01753	3.317e-63	219.0	COG0184@1|root,arCOG04185@2157|Archaea,41SKP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	rps15	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13_N,Ribosomal_S15
YYD2_k127_4939511_1	1459636.NTE_01707	3.414e-36	143.0	COG1909@1|root,arCOG04076@2157|Archaea,41SNQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0218 family	-	-	-	ko:K09735	-	-	-	-	ko00000	-	-	-	DUF359
YYD2_k127_4939511_0	1459636.NTE_01706	1.278e-139	448.0	COG0489@1|root,arCOG01846@1|root,arCOG00585@2157|Archaea,arCOG01846@2157|Archaea,41SF1@651137|Thaumarchaeota	651137|Thaumarchaeota	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
YYD2_k127_4949799_1	1459636.NTE_01675	1.271e-45	168.0	COG1199@1|root,arCOG00770@2157|Archaea,41T2V@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HELICc2	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_2
YYD2_k127_4949799_4	316274.Haur_2523	2.995e-11	70.0	COG0784@1|root,COG4191@1|root,COG5002@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,2G7PG@200795|Chloroflexi	2|Bacteria	T	ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02482,ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
YYD2_k127_4949799_6	1123371.ATXH01000001_gene1273	0.0003393	47.0	COG2204@1|root,COG2204@2|Bacteria,2GIFH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Magnesium chelatase, subunit ChlI	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_4949799_0	1459636.NTE_02290	1.387e-111	368.0	COG0024@1|root,arCOG01001@2157|Archaea,41SEA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YYD2_k127_4949799_2	1459636.NTE_02050	2.062e-23	104.0	COG3635@1|root,arCOG01696@2157|Archaea,41S6M@651137|Thaumarchaeota	651137|Thaumarchaeota	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
YYD2_k127_4959752_1	1459636.NTE_00196	1.502e-11	74.0	COG0467@1|root,arCOG01171@2157|Archaea	2157|Archaea	T	Circadian clock protein KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
YYD2_k127_4960511_1	1229909.NSED_09270	4.068e-11	72.0	arCOG07262@1|root,arCOG07262@2157|Archaea,41T8B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4960511_0	1459636.NTE_01377	1.899e-27	120.0	arCOG08731@1|root,arCOG08731@2157|Archaea,41STT@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4967929_1	1068980.ARVW01000001_gene4052	3.549e-42	161.0	COG3291@1|root,COG3291@2|Bacteria,2H4MA@201174|Actinobacteria,4EANI@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YYD2_k127_4967929_0	1459636.NTE_02637	3.202e-54	202.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	2157|Archaea	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
YYD2_k127_4968114_1	1459636.NTE_01567	2.736e-71	251.0	COG0122@1|root,arCOG00464@2157|Archaea,41SHE@651137|Thaumarchaeota	651137|Thaumarchaeota	L	8-oxoguanine DNA glycosylase	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YYD2_k127_4968114_0	1459636.NTE_03316	3.751e-189	599.0	COG1236@1|root,arCOG00541@2157|Archaea,41SAJ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B_6,RMMBL
YYD2_k127_4977413_1	1459636.NTE_01761	7.077e-19	85.0	COG1032@1|root,arCOG01363@2157|Archaea,41S6P@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD2_k127_4977413_0	246197.MXAN_3479	2.291e-68	243.0	2EYGB@1|root,33RQ8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4981027_1	1184251.TCELL_0023	1.667e-45	176.0	COG0478@1|root,arCOG01181@2157|Archaea,2XPM0@28889|Crenarchaeota	28889|Crenarchaeota	T	RIO-like serine threonine protein kinase fused to N-terminal HTH domain	-	-	2.7.11.1	ko:K07179	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1,Rio2_N
YYD2_k127_4981027_0	1459636.NTE_01726	9.61e-186	585.0	COG0192@1|root,arCOG07444@2157|Archaea,41S5P@651137|Thaumarchaeota	651137|Thaumarchaeota	H	S-adenosylmethionine synthetase	-	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YYD2_k127_4981513_1	3711.Bra006948.1-P	0.000452	51.0	COG1409@1|root,KOG1378@2759|Eukaryota,37IU0@33090|Viridiplantae,3G90S@35493|Streptophyta,3HRK0@3699|Brassicales	35493|Streptophyta	G	Purple acid phosphatase	-	GO:0003674,GO:0003824,GO:0003993,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_C,Pur_ac_phosph_N
YYD2_k127_4981513_0	1459636.NTE_02786	1.36e-65	226.0	COG4275@1|root,arCOG10427@2157|Archaea	2157|Archaea	S	Chromate resistance	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
YYD2_k127_5003389_0	1365176.N186_07020	2.064e-99	331.0	COG3839@1|root,arCOG00175@2157|Archaea,2XPUC@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
YYD2_k127_5013165_0	204669.Acid345_4475	1.53e-108	372.0	COG1793@1|root,COG1793@2|Bacteria,3Y3AP@57723|Acidobacteria,2JIGV@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
YYD2_k127_5013218_0	436308.Nmar_0978	1.06e-27	117.0	COG5012@1|root,arCOG03402@2157|Archaea	2157|Archaea	T	Cobalamin B12-binding domain protein	-	-	-	ko:K16955,ko:K22491	ko00920,map00920	-	R09997	RC00035	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2
YYD2_k127_5013218_1	1459636.NTE_00575	1.541e-20	93.0	arCOG04557@1|root,arCOG04557@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5014319_0	436308.Nmar_1695	1.919e-104	344.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
YYD2_k127_5014319_4	1459636.NTE_00055	4.757e-49	179.0	COG1733@1|root,arCOG01057@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
YYD2_k127_5014319_1	1459636.NTE_00056	1.36e-77	267.0	arCOG01792@1|root,arCOG01792@2157|Archaea	2157|Archaea	K	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
YYD2_k127_5014319_3	1459636.NTE_00057	1.354e-50	183.0	COG0394@1|root,arCOG04425@2157|Archaea,41T49@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YYD2_k127_5014319_2	1459636.NTE_00058	4.178e-72	250.0	COG0580@1|root,arCOG04431@2157|Archaea,41SJI@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Major Intrinsic Protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
YYD2_k127_5014319_5	926569.ANT_17120	1.527e-45	168.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441,ko:K10545,ko:K10548	ko02010,map02010	M00212,M00215,M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4,3.A.1.2.5	-	-	ABC_tran
YYD2_k127_5017715_0	1403313.AXBR01000002_gene4317	1.149e-08	69.0	COG1196@1|root,COG3953@1|root,COG5283@1|root,COG1196@2|Bacteria,COG3953@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus	91061|Bacilli	D	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,PhageMin_Tail,SLT,Sipho_tail
YYD2_k127_5024193_0	1459636.NTE_03491	2.18e-15	78.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_5026220_0	70448.Q0P3H6	6.941e-185	582.0	COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,34JA3@3041|Chlorophyta	3041|Chlorophyta	C	Belongs to the complex I 49 kDa subunit family	-	-	1.6.5.3,1.6.99.3	ko:K03935	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_49kDa
YYD2_k127_5031529_0	1459636.NTE_02657	2.944e-238	743.0	COG0644@1|root,arCOG00570@2157|Archaea,41SBB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5031529_2	1459636.NTE_01088	7.546e-35	135.0	arCOG08763@1|root,arCOG08763@2157|Archaea,41SWC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5031529_1	1459636.NTE_02053	2.192e-87	297.0	COG1405@1|root,arCOG01981@2157|Archaea,41S8Y@651137|Thaumarchaeota	651137|Thaumarchaeota	K	factor TFIIB	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
YYD2_k127_5044028_1	1459636.NTE_02767	7.474e-69	241.0	COG0470@1|root,arCOG00470@2157|Archaea,41S9F@651137|Thaumarchaeota	651137|Thaumarchaeota	L	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA
YYD2_k127_5044028_0	1459636.NTE_02766	1.157e-157	505.0	arCOG08783@1|root,arCOG08783@2157|Archaea,41SFX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5044028_2	1459636.NTE_02745	1.909e-13	70.0	COG0049@1|root,arCOG04254@2157|Archaea,41S6U@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YYD2_k127_5044694_1	431943.CKL_0403	2.248e-19	98.0	COG5017@1|root,COG5017@2|Bacteria,1V2RT@1239|Firmicutes,24NVB@186801|Clostridia,36MR2@31979|Clostridiaceae	186801|Clostridia	M	D-glucuronyl C5-epimerase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	C5-epim_C
YYD2_k127_5044730_1	1229909.NSED_01260	6.416e-233	730.0	COG4799@1|root,arCOG02705@2157|Archaea,41SEH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.15,6.4.1.2,6.4.1.3	ko:K18604	ko00720,ko01120,map00720,map01120	-	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko01000	-	-	-	Carboxyl_trans
YYD2_k127_5044730_0	1459636.NTE_02773	4.585e-238	744.0	COG0439@1|root,arCOG01590@2157|Archaea,41SXC@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Carbamoyl-phosphate synthase L chain	-	-	6.4.1.2,6.4.1.3	ko:K18603	ko00720,ko01120,map00720,map01120	-	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YYD2_k127_5044730_5	1459636.NTE_02774	4.043e-44	166.0	COG0511@1|root,arCOG02699@2157|Archaea	2157|Archaea	I	biotin carboxyl carrier	-	-	2.3.1.12,4.1.1.3	ko:K00627,ko:K01571,ko:K15037,ko:K18605	ko00010,ko00020,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200	M00307,M00375,M00741	R00209,R00217,R00742,R01859,R02569	RC00004,RC00040,RC00097,RC00367,RC00609,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,Biotin_lipoyl_2
YYD2_k127_5044730_4	1459636.NTE_02777	2.874e-58	206.0	COG1225@1|root,arCOG00310@2157|Archaea,41SKG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YYD2_k127_5044730_2	1459636.NTE_02778	1.513e-141	459.0	COG1104@1|root,arCOG00066@2157|Archaea,41SB1@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Cysteine desulfurase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YYD2_k127_5044730_3	1459636.NTE_02779	5.884e-86	292.0	COG1606@1|root,arCOG00043@2157|Archaea,41SF3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	tRNA methyl transferase	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	QueC
YYD2_k127_5045136_0	1459636.NTE_03146	6.372e-46	173.0	COG0071@1|root,arCOG01833@2157|Archaea	2157|Archaea	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YYD2_k127_5047442_4	1401064.HMPREF2129_03395	7.855e-07	53.0	COG1651@1|root,COG1651@2|Bacteria,2IGR9@201174|Actinobacteria,22KGY@1653|Corynebacteriaceae	201174|Actinobacteria	O	DSBA-like thioredoxin domain	dsbA	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YYD2_k127_5047442_0	1459636.NTE_01652	1.287e-136	453.0	COG4257@1|root,arCOG03564@2157|Archaea,41SM7@651137|Thaumarchaeota	651137|Thaumarchaeota	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
YYD2_k127_5047442_2	1131266.ARWQ01000014_gene96	2.67e-31	126.0	COG0346@1|root,arCOG02708@2157|Archaea,41T5Z@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD2_k127_5047442_1	1459636.NTE_02924	1.307e-109	362.0	COG1205@1|root,arCOG00555@2157|Archaea,41SZS@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
YYD2_k127_5048251_0	1459636.NTE_01493	2.877e-43	170.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YYD2_k127_5050894_0	1459636.NTE_00888	2.942e-33	135.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
YYD2_k127_5050894_1	596323.HMPREF0554_0316	3.592e-15	78.0	COG3189@1|root,COG3189@2|Bacteria,37CNK@32066|Fusobacteria	32066|Fusobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
YYD2_k127_5051298_1	1459636.NTE_01728	2.498e-115	379.0	COG1903@1|root,arCOG04383@2157|Archaea,41S70@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
YYD2_k127_5051298_0	1459636.NTE_01732	1.589e-127	417.0	COG2073@1|root,arCOG00651@2157|Archaea,41S83@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cobalamin synthesis G C-terminus	-	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,CbiG_mid
YYD2_k127_5051298_2	1459636.NTE_01733	1.306e-83	286.0	COG2082@1|root,COG2138@1|root,arCOG02246@2157|Archaea,arCOG02247@2157|Archaea,41SH6@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Cobalt chelatase (CbiK)	-	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiX
YYD2_k127_5051298_3	1459636.NTE_01733	7.372e-67	235.0	COG2082@1|root,COG2138@1|root,arCOG02246@2157|Archaea,arCOG02247@2157|Archaea,41SH6@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Cobalt chelatase (CbiK)	-	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiX
YYD2_k127_5051298_4	98439.AJLL01000070_gene1491	1.541e-30	125.0	COG4891@1|root,COG4891@2|Bacteria	2|Bacteria	K	PFAM Polyketide cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
YYD2_k127_5051801_2	404589.Anae109_1057	3.051e-05	52.0	COG0346@1|root,COG0346@2|Bacteria,1MV4D@1224|Proteobacteria	1224|Proteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD2_k127_5051801_1	1183438.GKIL_3641	3.266e-11	66.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD2_k127_5051801_0	404589.Anae109_1057	2.24e-18	87.0	COG0346@1|root,COG0346@2|Bacteria,1MV4D@1224|Proteobacteria	1224|Proteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD2_k127_5052419_3	1459636.NTE_03297	4.304e-47	175.0	COG0513@1|root,arCOG00558@2157|Archaea,41SM1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
YYD2_k127_5052419_0	1459636.NTE_00095	2.663e-81	273.0	COG1675@1|root,arCOG04270@2157|Archaea,41SJ8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes	tfe	-	-	ko:K03136	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIE_alpha
YYD2_k127_5052419_2	1459636.NTE_03545	2.818e-61	218.0	COG1985@1|root,arCOG01484@2157|Archaea,41SK2@651137|Thaumarchaeota	651137|Thaumarchaeota	H	RibD C-terminal domain	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
YYD2_k127_5052419_1	1459636.NTE_03546	2.993e-68	240.0	COG0402@1|root,arCOG00692@2157|Archaea,41S61@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD2_k127_5055449_0	1459636.NTE_01500	9.506e-165	527.0	COG0281@1|root,arCOG00853@2157|Archaea	2157|Archaea	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
YYD2_k127_5063480_0	1459636.NTE_00765	2.233e-52	190.0	COG0113@1|root,arCOG04300@2157|Archaea,41SET@651137|Thaumarchaeota	2157|Archaea	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
YYD2_k127_5063480_1	1459636.NTE_00762	4.172e-51	184.0	COG1064@1|root,arCOG01455@2157|Archaea,41SA9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_506592_2	1459636.NTE_02704	4.504e-22	96.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_506592_1	1459636.NTE_02704	3.28e-22	97.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5103344_0	1459636.NTE_02875	1.007e-22	101.0	COG0637@1|root,arCOG02293@2157|Archaea	2157|Archaea	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.18,5.4.2.6	ko:K01091,ko:K01838,ko:K07025	ko00500,ko00630,ko01100,ko01110,ko01130,map00500,map00630,map01100,map01110,map01130	-	R01334,R02728,R11310	RC00017,RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
YYD2_k127_5103344_2	1041930.Mtc_0829	1.604e-06	54.0	COG0637@1|root,arCOG02293@2157|Archaea,2XTYU@28890|Euryarchaeota,2NAS6@224756|Methanomicrobia	224756|Methanomicrobia	S	Haloacid dehalogenase-like hydrolase	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
YYD2_k127_5103344_3	1268303.RHODMAR_2039	4.571e-05	52.0	COG1765@1|root,COG1765@2|Bacteria,2IG8A@201174|Actinobacteria,4G0XA@85025|Nocardiaceae	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
YYD2_k127_5103344_1	153721.MYP_3078	1.149e-09	70.0	2EYGB@1|root,33RQ8@2|Bacteria,4P0AB@976|Bacteroidetes,47T9K@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5105723_0	1459636.NTE_03071	4.981e-63	221.0	COG0861@1|root,arCOG09430@2157|Archaea	2157|Archaea	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
YYD2_k127_5105723_1	1229909.NSED_01010	4.948e-09	62.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD2_k127_5128304_0	1459636.NTE_03297	1.924e-91	307.0	COG0513@1|root,arCOG00558@2157|Archaea,41SM1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
YYD2_k127_5128304_1	1459636.NTE_01054	4.333e-60	218.0	arCOG08023@1|root,arCOG08023@2157|Archaea,41SKK@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
YYD2_k127_5156525_1	1459636.NTE_02986	3.019e-179	569.0	COG0294@1|root,COG1410@1|root,arCOG01978@2157|Archaea,arCOG02029@2157|Archaea,41SXT@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind
YYD2_k127_5156525_2	1459636.NTE_01912	3.793e-85	290.0	COG0159@1|root,arCOG01086@2157|Archaea,41SG0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
YYD2_k127_5156525_0	1459636.NTE_01913	1.174e-192	607.0	COG0133@1|root,arCOG01433@2157|Archaea,41S87@651137|Thaumarchaeota	651137|Thaumarchaeota	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD2_k127_5156525_4	1459636.NTE_01914	1.286e-05	48.0	COG0134@1|root,arCOG01088@2157|Archaea,41SN7@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Indole-3-glycerol phosphate synthase	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
YYD2_k127_5157413_3	1459636.NTE_02463	9.821e-15	74.0	COG2167@1|root,arCOG04177@2157|Archaea,41SUT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL39 family	rpl39e	-	-	ko:K02924	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L39
YYD2_k127_5157413_0	1459636.NTE_02464	1.559e-32	128.0	COG2097@1|root,arCOG04473@2157|Archaea,41STQ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the ribosomal protein L31e family	rpl31e	-	-	ko:K02910	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31e
YYD2_k127_5157413_1	1459636.NTE_00426	1.547e-19	91.0	arCOG08809@1|root,arCOG08809@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5157413_2	1459636.NTE_00425	1.515e-15	78.0	COG1711@1|root,arCOG00551@2157|Archaea,41SVQ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	protein conserved in archaea	-	-	-	ko:K09723	-	-	-	-	ko00000,ko03032	-	-	-	-
YYD2_k127_5166180_2	436308.Nmar_1661	3.515e-41	156.0	COG1733@1|root,arCOG01057@2157|Archaea,41T7C@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
YYD2_k127_5166180_3	1230341.MJ3_02877	1.67e-23	102.0	COG0477@1|root,COG2814@2|Bacteria,1UXXX@1239|Firmicutes,4HC83@91061|Bacilli	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
YYD2_k127_5166180_1	1124780.ANNU01000079_gene2592	3.018e-42	161.0	COG0477@1|root,COG2814@2|Bacteria,4NEN9@976|Bacteroidetes,47KR8@768503|Cytophagia	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD2_k127_5168683_0	1459636.NTE_03030	1.914e-46	173.0	COG2453@1|root,arCOG03413@2157|Archaea,41SK5@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Dual specificity phosphatase, catalytic domain	-	-	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	DSPc
YYD2_k127_5168683_1	373903.Hore_15890	6.095e-32	137.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,25CN4@186801|Clostridia,3WB2H@53433|Halanaerobiales	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
YYD2_k127_5179035_0	1459636.NTE_02036	2.694e-206	645.0	COG0422@1|root,arCOG02741@2157|Archaea,41S5Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Thiamine biosynthesis protein ThiC	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
YYD2_k127_5179035_1	1459636.NTE_01522	1.581e-160	516.0	COG1960@1|root,arCOG01707@2157|Archaea	2157|Archaea	I	COG1960 Acyl-CoA dehydrogenases	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YYD2_k127_5179035_2	1459636.NTE_02210	1.679e-77	269.0	COG0010@1|root,arCOG01700@2157|Archaea,41T23@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
YYD2_k127_5179035_3	1131266.ARWQ01000002_gene639	1.097e-18	92.0	COG1917@1|root,arCOG03444@2157|Archaea,41SV4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD2_k127_5179035_5	1459636.NTE_00236	1.34e-06	55.0	arCOG09752@1|root,arCOG09752@2157|Archaea,41T9M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5184619_0	1459636.NTE_01297	0.0002817	44.0	COG0011@1|root,arCOG04373@2157|Archaea,41T99@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
YYD2_k127_5185855_0	1459636.NTE_01740	3.644e-61	214.0	COG1607@1|root,arCOG00773@2157|Archaea,41T2J@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
YYD2_k127_5185855_1	886882.PPSC2_c2409	1.041e-19	96.0	COG2133@1|root,COG2133@2|Bacteria,1VBUK@1239|Firmicutes,4HKNP@91061|Bacilli,26YMI@186822|Paenibacillaceae	91061|Bacilli	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
YYD2_k127_5191358_0	373903.Hore_07040	3.511e-09	60.0	COG3360@1|root,COG3360@2|Bacteria,1VF2X@1239|Firmicutes,24QS4@186801|Clostridia	186801|Clostridia	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
YYD2_k127_5200286_0	765420.OSCT_0924	3.528e-30	134.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,ThiF
YYD2_k127_5201040_0	5762.XP_002672067.1	1.68e-19	100.0	COG1409@1|root,KOG1378@2759|Eukaryota	2759|Eukaryota	E	acid phosphatase activity	-	GO:0000003,GO:0003674,GO:0003824,GO:0003993,GO:0004721,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005615,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005829,GO:0005911,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007275,GO:0008150,GO:0008152,GO:0008199,GO:0008270,GO:0009267,GO:0009505,GO:0009506,GO:0009605,GO:0009791,GO:0009845,GO:0009846,GO:0009856,GO:0009987,GO:0009991,GO:0016036,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0022414,GO:0030054,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032501,GO:0032502,GO:0033554,GO:0036211,GO:0042578,GO:0042592,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044706,GO:0046872,GO:0046914,GO:0048856,GO:0048878,GO:0050801,GO:0050896,GO:0051704,GO:0051716,GO:0055044,GO:0055062,GO:0055081,GO:0055083,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071944,GO:0072505,GO:0072506,GO:0090351,GO:0098771,GO:0140096,GO:1901564	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_C,Pur_ac_phosph_N
YYD2_k127_5202916_0	1459636.NTE_00389	1.455e-83	285.0	COG0475@1|root,arCOG01955@2157|Archaea,41SG1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
YYD2_k127_5224802_0	1459636.NTE_01106	1.546e-64	228.0	COG0367@1|root,arCOG04741@1|root,arCOG00071@2157|Archaea,arCOG04741@2157|Archaea,41SMA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
YYD2_k127_5225868_1	1459636.NTE_02286	7.873e-30	120.0	arCOG08688@1|root,arCOG08688@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5225868_4	1459636.NTE_01643	3.753e-13	70.0	arCOG10403@1|root,arCOG10403@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5225868_3	1459636.NTE_01642	2.483e-14	76.0	arCOG08666@1|root,arCOG08666@2157|Archaea,41SVR@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5225868_5	985053.VMUT_0437	7.035e-09	57.0	COG1052@1|root,arCOG01755@2157|Archaea,2XPN8@28889|Crenarchaeota	28889|Crenarchaeota	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	gyaR	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YYD2_k127_5225868_0	1459636.NTE_02310	6.672e-81	276.0	COG1052@1|root,arCOG01755@2157|Archaea,41T1D@651137|Thaumarchaeota	651137|Thaumarchaeota	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YYD2_k127_5226494_0	983545.Glaag_0760	1.575e-28	124.0	COG0428@1|root,COG0428@2|Bacteria,1N3QA@1224|Proteobacteria,1RR8U@1236|Gammaproteobacteria,466K5@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	divalent heavy-metal cations transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
YYD2_k127_5226690_0	1459636.NTE_01810	6.929e-49	184.0	COG0132@1|root,arCOG00100@2157|Archaea,41SQX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
YYD2_k127_5283252_0	1459636.NTE_03103	1.002e-215	685.0	COG1164@1|root,arCOG04758@2157|Archaea,41S7J@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YYD2_k127_5283252_5	1459636.NTE_02877	9.504e-43	161.0	arCOG08781@1|root,arCOG08781@2157|Archaea	1459636.NTE_02877|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5283252_2	1459636.NTE_01385	1.922e-66	235.0	COG1650@1|root,arCOG01616@2157|Archaea,41SM3@651137|Thaumarchaeota	651137|Thaumarchaeota	J	D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo	dtdA	-	3.1.1.96	ko:K09716	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_deacylase
YYD2_k127_5283252_3	1459636.NTE_01387	1.593e-59	209.0	COG2147@1|root,arCOG04089@2157|Archaea,41SVC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl19e	-	-	ko:K02885	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19e
YYD2_k127_5283252_4	1459636.NTE_01388	6.339e-53	190.0	COG1717@1|root,arCOG00781@2157|Archaea,41SP5@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02912	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L32e
YYD2_k127_5283252_1	1229909.NSED_01900	4.958e-116	375.0	COG0605@1|root,arCOG04147@2157|Archaea,41S6C@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
YYD2_k127_5283534_4	1459636.NTE_03036	3.746e-20	94.0	COG1412@1|root,arCOG04312@2157|Archaea,41SUY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Nucleotide binding protein, PINc	-	-	-	ko:K07158	-	-	-	-	ko00000	-	-	-	Fcf1
YYD2_k127_5283534_2	1459636.NTE_03037	7.909e-76	260.0	COG2220@1|root,arCOG00497@2157|Archaea	2157|Archaea	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
YYD2_k127_5283534_3	1459636.NTE_02473	8.848e-76	258.0	COG0526@1|root,arCOG00314@2157|Archaea,41SKE@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD2_k127_5283534_0	1459636.NTE_02483	1.824e-300	933.0	COG0556@1|root,arCOG04748@2157|Archaea,41T0H@651137|Thaumarchaeota	651137|Thaumarchaeota	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YYD2_k127_5283534_1	1459636.NTE_02484	3.098e-177	563.0	COG0178@1|root,arCOG04694@2157|Archaea,41T01@651137|Thaumarchaeota	651137|Thaumarchaeota	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YYD2_k127_5298954_1	1459636.NTE_01292	2.225e-33	140.0	COG0552@1|root,arCOG01227@2157|Archaea,41SCC@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
YYD2_k127_5298954_0	1459636.NTE_01293	1.345e-129	419.0	COG0448@1|root,arCOG00912@2157|Archaea,41SEY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YYD2_k127_5300568_1	1459636.NTE_00744	6.063e-140	452.0	COG0657@1|root,arCOG02638@2157|Archaea	2157|Archaea	I	Alpha beta hydrolase	-	-	3.1.1.83	ko:K01066,ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
YYD2_k127_5300568_0	269797.Mbar_A0813	4.995e-145	471.0	COG0477@1|root,arCOG00130@2157|Archaea,2XVFS@28890|Euryarchaeota,2NAF6@224756|Methanomicrobia	224756|Methanomicrobia	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
YYD2_k127_531420_2	1459636.NTE_01987	2.884e-20	92.0	arCOG05491@1|root,arCOG05491@2157|Archaea,41SVB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_531420_0	1459636.NTE_01229	7.802e-162	514.0	COG0214@1|root,arCOG04075@2157|Archaea,41SEJ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the PdxS SNZ family	-	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
YYD2_k127_531420_1	1459636.NTE_01228	3.034e-73	252.0	COG0311@1|root,arCOG00034@2157|Archaea,41SIZ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
YYD2_k127_5321538_0	1459636.NTE_01234	3.795e-162	514.0	COG1013@1|root,arCOG01599@2157|Archaea,41SAB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
YYD2_k127_5321538_1	1459636.NTE_00961	1.698e-130	418.0	arCOG08676@1|root,arCOG08676@2157|Archaea,41SCF@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Archaeal ammonia monooxygenase subunit A (AmoA)	-	-	1.14.18.3,1.14.99.39	ko:K10944	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Archaeal_AmoA
YYD2_k127_5321538_3	1459636.NTE_00962	1.337e-44	163.0	arCOG10586@1|root,arCOG10586@2157|Archaea,41STH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5321538_2	1459636.NTE_01090	7.388e-76	259.0	arCOG08675@1|root,arCOG08675@2157|Archaea,41SI5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Monooxygenase subunit B protein	-	-	-	ko:K10945	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002	-	-	-	Monooxygenase_B
YYD2_k127_5321538_4	1459636.NTE_01751	1.05e-39	149.0	arCOG08672@1|root,arCOG08672@2157|Archaea,41SU2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5321538_6	1229909.NSED_08290	1.996e-05	51.0	arCOG10587@1|root,arCOG10587@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5321538_5	436308.Nmar_1508	6.08e-10	61.0	COG0184@1|root,arCOG04185@2157|Archaea,41SKP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	rps15	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13_N,Ribosomal_S15
YYD2_k127_5331517_11	1459636.NTE_02226	6.72e-36	138.0	COG0099@1|root,arCOG01722@2157|Archaea,41SIW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YYD2_k127_5331517_3	1459636.NTE_02229	1.545e-204	650.0	COG1239@1|root,arCOG00438@2157|Archaea	2157|Archaea	H	magnesium chelatase	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5
YYD2_k127_5331517_4	1459636.NTE_02230	5.584e-190	604.0	COG2304@1|root,arCOG02900@2157|Archaea	2157|Archaea	O	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YYD2_k127_5331517_7	1459636.NTE_00598	1.507e-120	392.0	COG0714@1|root,arCOG00441@2157|Archaea,41SDZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5
YYD2_k127_5331517_2	1459636.NTE_00599	6.113e-221	697.0	COG2304@1|root,arCOG02900@2157|Archaea,41SDY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5331517_8	1459636.NTE_00600	7.612e-102	335.0	COG0176@1|root,arCOG05061@2157|Archaea,41S99@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
YYD2_k127_5331517_6	1459636.NTE_00601	5.15e-135	436.0	COG3958@1|root,arCOG01051@2157|Archaea,41SEP@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
YYD2_k127_5331517_0	1459636.NTE_00602	8.511e-265	824.0	COG0036@1|root,COG3959@1|root,arCOG01053@2157|Archaea,arCOG05046@2157|Archaea,41SBE@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim,Transketolase_N
YYD2_k127_5331517_5	1459636.NTE_00604	2.807e-159	515.0	COG0260@1|root,arCOG04322@2157|Archaea,41SYD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
YYD2_k127_5331517_1	1131266.ARWQ01000015_gene746	6.852e-248	778.0	COG1245@1|root,arCOG00187@2157|Archaea,41S8K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	RNase L inhibitor, RLI	-	-	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
YYD2_k127_5331517_9	1459636.NTE_00608	8.657e-96	321.0	COG2520@1|root,arCOG00033@2157|Archaea,41S7P@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Met-10+ like-protein	-	-	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Met_10
YYD2_k127_5331517_10	1459636.NTE_00612	9.992e-77	259.0	COG0456@1|root,arCOG00833@2157|Archaea,41SIY@651137|Thaumarchaeota	651137|Thaumarchaeota	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
YYD2_k127_5334270_3	1459636.NTE_03149	1.173e-43	166.0	COG0576@1|root,arCOG04772@2157|Archaea,41SSU@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	-	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YYD2_k127_5334270_0	1459636.NTE_03148	3.684e-313	968.0	COG0443@1|root,arCOG03060@2157|Archaea,41SCM@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YYD2_k127_5334270_1	1459636.NTE_03147	1.989e-157	504.0	COG0484@1|root,arCOG06880@1|root,arCOG02846@2157|Archaea,arCOG06880@2157|Archaea,41SCZ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DnaJ central domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YYD2_k127_5334270_2	1459636.NTE_03146	1.51e-61	217.0	COG0071@1|root,arCOG01833@2157|Archaea	2157|Archaea	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YYD2_k127_5350221_0	1459636.NTE_01283	0.0	1204.0	COG0013@1|root,arCOG01255@2157|Archaea,41SBJ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YYD2_k127_5350221_2	1459636.NTE_01281	2.139e-48	175.0	COG0526@1|root,arCOG01972@2157|Archaea,41SSR@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YYD2_k127_5350221_1	439235.Dalk_2335	7.534e-54	200.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria,2MI2V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
YYD2_k127_5368909_0	545697.HMPREF0216_02913	1.32e-11	70.0	COG0745@1|root,COG0745@2|Bacteria,1U4FM@1239|Firmicutes,24DF2@186801|Clostridia,36GMR@31979|Clostridiaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K18344	ko01502,ko02020,map01502,map02020	M00651,M00656	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_5369529_0	1459636.NTE_02033	4.419e-86	286.0	COG0074@1|root,arCOG01339@2157|Archaea,41SEU@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
YYD2_k127_5369529_1	1459636.NTE_02021	4.079e-66	235.0	COG2263@1|root,arCOG00910@2157|Archaea,41S85@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5369529_2	1459636.NTE_03289	1.002e-54	196.0	COG1781@1|root,arCOG04229@2157|Archaea,41SJT@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Involved in allosteric regulation of aspartate carbamoyltransferase	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
YYD2_k127_5369529_3	436308.Nmar_1688	2.246e-16	82.0	COG0636@1|root,arCOG02455@2157|Archaea,41T6A@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
YYD2_k127_5387824_0	1459636.NTE_02735	0.0	1059.0	COG1241@1|root,arCOG00439@2157|Archaea,41SA7@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Belongs to the MCM family	-	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	MCM,MCM_N,MCM_OB
YYD2_k127_5387824_2	1459636.NTE_02736	4.432e-53	192.0	arCOG00552@1|root,arCOG00552@2157|Archaea,41SRW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	GINS complex protein	-	-	-	ko:K09723	-	-	-	-	ko00000,ko03032	-	-	-	Sld5
YYD2_k127_5387824_1	1459636.NTE_02737	1.215e-86	293.0	COG0470@1|root,arCOG00469@2157|Archaea,41SFJ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Replication factor C	-	-	-	ko:K04801	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	DNA_pol3_delta2,Rep_fac_C,RuvB_N
YYD2_k127_5388620_0	237368.SCABRO_00472	1.042e-07	59.0	2CK24@1|root,33099@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5395514_1	1298880.AUEV01000002_gene1333	3.767e-12	68.0	COG3467@1|root,COG3467@2|Bacteria,2IFRI@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
YYD2_k127_5395514_2	656024.FsymDg_0437	5.384e-09	58.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
YYD2_k127_5395514_0	1408444.JHYC01000011_gene998	1.309e-159	509.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RN4D@1236|Gammaproteobacteria,1JD2W@118969|Legionellales	118969|Legionellales	C	Zinc-binding dehydrogenase	yahK	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_5396554_1	1009858.BUMPG002_CDS00317	0.0001621	46.0	COG0697@1|root,COG0697@2|Bacteria,1PJT0@1224|Proteobacteria,1RZG8@1236|Gammaproteobacteria,37D7G@32199|Buchnera	1236|Gammaproteobacteria	EG	EamA-like transporter family	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
YYD2_k127_5396554_0	1121382.JQKG01000020_gene1208	1.219e-50	188.0	COG1028@1|root,COG1028@2|Bacteria	1121382.JQKG01000020_gene1208|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_539952_1	1459636.NTE_03520	6.128e-51	191.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_03520|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_539952_0	342949.PNA2_0513	5.163e-115	398.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,243CX@183968|Thermococci	183968|Thermococci	L	ERCC4 domain	-	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,Helicase_C
YYD2_k127_539952_2	186497.PF1902	1.598e-13	71.0	COG1061@1|root,arCOG00874@2157|Archaea,2XTYQ@28890|Euryarchaeota,243Y9@183968|Thermococci	183968|Thermococci	K	ERCC3/RAD25/XPB C-terminal helicase	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,ResIII
YYD2_k127_540170_0	1459636.NTE_02484	3.413e-285	887.0	COG0178@1|root,arCOG04694@2157|Archaea,41T01@651137|Thaumarchaeota	651137|Thaumarchaeota	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YYD2_k127_540170_1	1229909.NSED_06405	9.053e-41	155.0	COG0322@1|root,arCOG04753@2157|Archaea,41SX9@651137|Thaumarchaeota	651137|Thaumarchaeota	L	TIGRFAM excinuclease ABC, C subunit	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
YYD2_k127_54051_1	1459636.NTE_00105	1.323e-43	163.0	COG1545@1|root,arCOG01285@2157|Archaea,41SQK@651137|Thaumarchaeota	651137|Thaumarchaeota	V	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
YYD2_k127_54051_0	1459636.NTE_00104	4.57e-218	681.0	COG0183@1|root,arCOG01278@2157|Archaea,41SCI@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
YYD2_k127_5428416_0	1459636.NTE_02810	3.067e-119	388.0	COG0330@1|root,arCOG01915@2157|Archaea	2157|Archaea	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YYD2_k127_5428416_1	868131.MSWAN_1638	3.375e-05	50.0	arCOG08550@1|root,arCOG08550@2157|Archaea	2157|Archaea	T	Putative antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	VAPB_antitox
YYD2_k127_5429342_0	1147.D082_15950	1.929e-19	100.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1H69I@1142|Synechocystis	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YYD2_k127_5435241_3	1459636.NTE_03546	1.03e-40	156.0	COG0402@1|root,arCOG00692@2157|Archaea,41S61@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD2_k127_5435241_1	1459636.NTE_03547	9.516e-69	241.0	COG2429@1|root,arCOG04202@2157|Archaea,41SHK@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity	gch3	-	3.5.4.29	ko:K08096	ko00740,ko01100,map00740,map01100	-	R07306	RC01790	ko00000,ko00001,ko01000	-	-	-	GCH_III
YYD2_k127_5435241_2	1459636.NTE_03548	1.399e-47	175.0	COG0054@1|root,arCOG01323@2157|Archaea,41SQ6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
YYD2_k127_5435241_0	1459636.NTE_03549	9.857e-87	291.0	COG0108@1|root,arCOG01320@2157|Archaea,41SFW@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	-	-	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase
YYD2_k127_5439671_0	436308.Nmar_1669	1.259e-05	55.0	arCOG08825@1|root,arCOG08825@2157|Archaea,41T1X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5439840_4	1459636.NTE_01238	3.42e-38	143.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01238|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5439840_1	1459636.NTE_01333	1.869e-61	222.0	arCOG08708@1|root,arCOG08708@2157|Archaea,41SPK@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5439840_2	1459636.NTE_00429	4.354e-45	168.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5439840_0	1459636.NTE_01608	3.776e-100	329.0	COG2406@1|root,arCOG01093@2157|Archaea,41S6X@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
YYD2_k127_5439840_5	1459636.NTE_01904	2.192e-29	123.0	arCOG08653@1|root,arCOG08653@2157|Archaea,41T9H@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5439840_3	1229909.NSED_04560	8.737e-41	159.0	COG1651@1|root,arCOG02868@2157|Archaea,41T2A@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YYD2_k127_5443437_1	1459636.NTE_02769	2.347e-20	92.0	arCOG08785@1|root,arCOG08785@2157|Archaea,41SVD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
YYD2_k127_5443437_2	1459636.NTE_02768	7.071e-18	87.0	arCOG08784@1|root,arCOG08784@2157|Archaea,41SVZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5443437_0	1459636.NTE_02767	4.026e-30	126.0	COG0470@1|root,arCOG00470@2157|Archaea,41S9F@651137|Thaumarchaeota	651137|Thaumarchaeota	L	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA
YYD2_k127_5446526_2	1131266.ARWQ01000002_gene583	1.402e-18	89.0	arCOG10549@1|root,arCOG10549@2157|Archaea,41STE@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5446526_1	1304284.L21TH_1812	5.562e-65	226.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,36WW8@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YYD2_k127_5446526_0	1459636.NTE_01844	5.42e-94	314.0	COG0026@1|root,arCOG01597@2157|Archaea,41SD9@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
YYD2_k127_5450902_1	1459636.NTE_01560	1.834e-61	216.0	COG1573@1|root,arCOG00905@2157|Archaea,41SJ1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YYD2_k127_5450902_2	985053.VMUT_0848	2.703e-45	171.0	COG0328@1|root,arCOG02942@2157|Archaea,2XR72@28889|Crenarchaeota	28889|Crenarchaeota	L	Reverse transcriptase-like	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
YYD2_k127_5450902_3	1459636.NTE_02216	2.929e-37	144.0	arCOG10514@1|root,arCOG10514@2157|Archaea,41STR@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5450902_0	1459636.NTE_02215	2.243e-100	337.0	COG0392@1|root,arCOG00899@2157|Archaea,41SFV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YYD2_k127_5450902_4	1459636.NTE_02213	3.626e-14	76.0	COG1100@1|root,arCOG01225@2157|Archaea,41T0A@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	ATP_bind_1
YYD2_k127_5459798_1	1459636.NTE_00487	4.088e-70	247.0	COG1475@1|root,arCOG11113@2157|Archaea	2157|Archaea	K	TIGRFAM ParB RepB Spo0J family partition protein	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YYD2_k127_5459798_0	1459636.NTE_00462	1.265e-87	298.0	COG0455@1|root,arCOG00589@2157|Archaea	2157|Archaea	D	COG0455 ATPases involved in chromosome partitioning	-	-	-	ko:K03496,ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
YYD2_k127_5459798_2	867903.ThesuDRAFT_01767	3.086e-10	66.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,3WD8H@538999|Clostridiales incertae sedis	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_5462473_0	1179778.PMM47T1_10225	4.234e-06	51.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,1S427@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YYD2_k127_5464029_0	1459636.NTE_02221	4.825e-190	597.0	COG0604@1|root,arCOG01458@2157|Archaea,41SZ9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_54685_1	192952.MM_0232	3.15e-11	68.0	COG3324@1|root,arCOG04946@2157|Archaea,2Y3YR@28890|Euryarchaeota,2NB03@224756|Methanomicrobia	224756|Methanomicrobia	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
YYD2_k127_54685_0	1116472.MGMO_53c00490	2.167e-119	402.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1XEPE@135618|Methylococcales	135618|Methylococcales	L	DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
YYD2_k127_5472639_1	1459636.NTE_02324	6.275e-28	117.0	COG1164@1|root,arCOG04758@2157|Archaea	2157|Archaea	E	oligoendopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
YYD2_k127_5472639_0	1459636.NTE_02217	1.26e-63	225.0	COG5491@1|root,arCOG00452@2157|Archaea,41SJ3@651137|Thaumarchaeota	2157|Archaea	D	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	Snf7
YYD2_k127_5472639_2	1459636.NTE_02683	2.939e-05	48.0	COG0177@1|root,arCOG00459@2157|Archaea,41SFM@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YYD2_k127_5479642_1	671143.DAMO_2848	3.749e-06	59.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2NNX4@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027	CBS,IMPDH,NMO
YYD2_k127_5479642_0	1459636.NTE_01459	5.088e-64	227.0	COG0144@1|root,arCOG00973@2157|Archaea	2157|Archaea	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016427,GO:0016428,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
YYD2_k127_5489807_0	1459636.NTE_00089	1.352e-27	117.0	COG0109@1|root,arCOG03103@2157|Archaea	2157|Archaea	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
YYD2_k127_5489807_1	1459636.NTE_01553	5.972e-05	45.0	arCOG12283@1|root,arCOG12283@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5493842_0	253839.SSNG_00242	1.174e-25	122.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,SLH
YYD2_k127_5496862_0	1459636.NTE_01493	4.148e-40	160.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YYD2_k127_5497790_0	926550.CLDAP_36650	5.782e-76	261.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
YYD2_k127_5497790_2	1191523.MROS_1014	7.219e-07	55.0	2EHX5@1|root,33BNR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5497790_1	1203566.HMPREF1285_01506	1.196e-16	81.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,22JPX@1653|Corynebacteriaceae	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_5499541_6	1459636.NTE_01348	1.652e-58	209.0	COG1948@1|root,arCOG04206@2157|Archaea,41SIH@651137|Thaumarchaeota	651137|Thaumarchaeota	L	ERCC4 domain	-	-	-	ko:K10848	ko03420,ko03460,map03420,map03460	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	ERCC4,HHH_5
YYD2_k127_5499541_4	1459636.NTE_02410	1.352e-70	245.0	COG3467@1|root,arCOG00520@2157|Archaea,41SJ5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
YYD2_k127_5499541_1	1459636.NTE_01248	6.338e-154	492.0	COG1522@1|root,arCOG01628@2157|Archaea,41SA2@651137|Thaumarchaeota	651137|Thaumarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5499541_5	1459636.NTE_01384	1.476e-68	239.0	COG0250@1|root,arCOG01920@2157|Archaea,41SM6@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor Spt5	spt5	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,Spt5-NGN
YYD2_k127_5499541_3	1459636.NTE_01197	3.094e-75	255.0	COG0080@1|root,arCOG04372@2157|Archaea,41SJW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rpl11	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
YYD2_k127_5499541_0	1459636.NTE_01192	2.866e-282	875.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
YYD2_k127_5499541_7	1459636.NTE_02718	6.832e-51	186.0	COG1056@1|root,arCOG00972@2157|Archaea,41T7B@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cytidylyltransferase-like	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
YYD2_k127_5499541_2	1459636.NTE_02721	8.11e-122	402.0	COG0252@1|root,arCOG01924@2157|Archaea,41SD7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatD	-	6.3.5.7	ko:K09482	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	Asparaginase
YYD2_k127_5502973_0	1459636.NTE_01788	5.469e-80	272.0	COG5491@1|root,arCOG00452@2157|Archaea,41T30@651137|Thaumarchaeota	651137|Thaumarchaeota	D	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5502973_1	1459636.NTE_01789	2.788e-29	121.0	arCOG08722@1|root,arCOG08722@2157|Archaea,41SSI@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5502973_2	1459636.NTE_01790	1.782e-17	84.0	COG0156@1|root,arCOG00113@2157|Archaea,41SAP@651137|Thaumarchaeota	651137|Thaumarchaeota	E	8-amino-7-oxononanoate synthase	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD2_k127_5507710_1	933262.AXAM01000126_gene962	1.617e-51	205.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BSJ@68525|delta/epsilon subdivisions,2X73B@28221|Deltaproteobacteria,2MI6A@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
YYD2_k127_5507710_0	1459636.NTE_01052	2.636e-57	223.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_5507710_4	1459636.NTE_01491	2.578e-23	104.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5507710_2	1121324.CLIT_2c02800	1.234e-49	184.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cadherin-like,Lactonase,PKD,TIG
YYD2_k127_5507710_3	1459636.NTE_02554	5.762e-31	121.0	COG1143@1|root,arCOG01543@2157|Archaea,41SGW@651137|Thaumarchaeota	651137|Thaumarchaeota	C	4Fe-4S binding domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_4
YYD2_k127_5524490_4	400682.PAC_15715998	0.0001211	45.0	KOG2177@1|root,KOG2177@2759|Eukaryota	2759|Eukaryota	O	zinc ion binding	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD2_k127_5524490_2	400682.PAC_15712501	2.265e-07	54.0	KOG2177@1|root,KOG2177@2759|Eukaryota,38X1Z@33154|Opisthokonta,3BJY7@33208|Metazoa	400682.PAC_15712501|-	O	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5524490_3	521011.Mpal_0423	4.927e-06	49.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
YYD2_k127_5524490_1	35128.Thaps261694	1.287e-14	86.0	COG1409@1|root,KOG1378@2759|Eukaryota,2XFBU@2836|Bacillariophyta	2836|Bacillariophyta	G	Iron/zinc purple acid phosphatase-like protein C	-	-	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_C
YYD2_k127_5524490_0	1459636.NTE_02513	1.857e-19	90.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	1459636.NTE_02513|-	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	-
YYD2_k127_5536058_2	1459636.NTE_00934	5.17e-22	96.0	COG0592@1|root,arCOG00488@2157|Archaea,41S6E@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication	pcn	-	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
YYD2_k127_5536058_0	1459636.NTE_00945	1.427e-33	132.0	COG1594@1|root,arCOG00579@2157|Archaea,41SS3@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family	-	-	-	ko:K03057	ko01100,map01100	-	-	-	br01611,ko00000,ko03021	-	-	-	TFIIS_C
YYD2_k127_5536058_3	1459636.NTE_00946	1.043e-17	85.0	COG1761@1|root,arCOG04111@2157|Archaea,41SV9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	RNA polymerase Rpb3/Rpb11 dimerisation domain	-	-	2.7.7.6	ko:K03056	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_L_2
YYD2_k127_5536058_1	1459636.NTE_00947	9.566e-30	121.0	arCOG08749@1|root,arCOG08749@2157|Archaea,41SRV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5540580_0	572546.Arcpr_0590	2.738e-120	399.0	COG0383@1|root,arCOG03661@2157|Archaea,2XVNX@28890|Euryarchaeota	28890|Euryarchaeota	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
YYD2_k127_5540580_1	1267211.KI669560_gene1938	3.77e-06	49.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IPMW@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
YYD2_k127_5542574_1	1459636.NTE_01057	2.467e-13	70.0	COG1599@1|root,arCOG01510@2157|Archaea,41S9M@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
YYD2_k127_5542574_2	391625.PPSIR1_04123	5.684e-05	46.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YXY8@29|Myxococcales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_5542574_0	1459636.NTE_01056	5.519e-20	91.0	COG1131@1|root,arCOG00196@2157|Archaea,41S9H@651137|Thaumarchaeota	651137|Thaumarchaeota	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_5542875_1	1463825.JNXC01000040_gene5132	1.155e-05	52.0	2BGAN@1|root,32A83@2|Bacteria,2GPQS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5542875_0	1229909.NSED_08905	1.451e-13	72.0	arCOG02240@1|root,arCOG02240@2157|Archaea,41SSM@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
YYD2_k127_5561613_0	1459636.NTE_03136	1.731e-47	184.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41SXB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5565070_0	1459636.NTE_01702	8.79e-81	271.0	COG0379@1|root,arCOG04459@2157|Archaea,41S6Y@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
YYD2_k127_5565070_1	1459636.NTE_01698	1.097e-77	268.0	COG1712@1|root,arCOG00254@2157|Archaea,41SGA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
YYD2_k127_5565070_2	1459636.NTE_01696	4.953e-25	108.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
YYD2_k127_5565070_4	1459636.NTE_01273	1.374e-16	82.0	arCOG03899@1|root,arCOG03899@2157|Archaea	2157|Archaea	L	endonuclease	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	HNH,HNH_3
YYD2_k127_5565070_5	1229909.NSED_07430	8.81e-12	75.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5573447_1	1121859.KB890754_gene820	0.0001765	46.0	COG4325@1|root,COG4325@2|Bacteria,4NFB6@976|Bacteroidetes,47N5E@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
YYD2_k127_5573447_0	243231.GSU1723	1.26e-14	79.0	COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,42MXP@68525|delta/epsilon subdivisions,2WMI1@28221|Deltaproteobacteria,43S3A@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YYD2_k127_5584050_0	1459636.NTE_00373	2.21e-46	175.0	COG2124@1|root,arCOG02814@2157|Archaea	2157|Archaea	C	cytochrome P450	cyp119	-	1.11.1.7,1.14.14.1	ko:K00493,ko:K21201	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
YYD2_k127_5584050_1	521011.Mpal_1421	6.864e-07	51.0	COG3291@1|root,COG3391@1|root,arCOG02508@2157|Archaea,arCOG03563@2157|Archaea,2Y2RX@28890|Euryarchaeota,2NAHT@224756|Methanomicrobia	224756|Methanomicrobia	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PKD
YYD2_k127_5589093_0	1459636.NTE_03092	4.313e-103	351.0	COG3408@1|root,arCOG03287@2157|Archaea	2157|Archaea	G	Glycogen debranching enzyme	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	GDE_C,GDE_N_bis,Trehalase
YYD2_k127_5589093_1	1459636.NTE_00139	1.129e-37	148.0	COG0438@1|root,arCOG04796@2157|Archaea,41T9D@651137|Thaumarchaeota	2157|Archaea	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YYD2_k127_5589996_0	1459636.NTE_02188	1.193e-60	216.0	COG4742@1|root,arCOG04362@2157|Archaea,41SGE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
YYD2_k127_5590916_2	436308.Nmar_0774	2.87e-68	236.0	COG0805@1|root,arCOG01919@2157|Archaea,41S69@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YYD2_k127_5590916_0	1459636.NTE_00682	0.0	1149.0	COG0417@1|root,arCOG15272@2157|Archaea,41S91@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA polymerase	-	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1
YYD2_k127_5590916_1	1459636.NTE_00681	2.712e-107	357.0	COG0010@1|root,arCOG01700@2157|Archaea,41T03@651137|Thaumarchaeota	2157|Archaea	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
YYD2_k127_5590916_3	445975.COLSTE_02536	4.259e-18	89.0	2AU0F@1|root,31JKB@2|Bacteria,2IT83@201174|Actinobacteria	201174|Actinobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_561392_0	1459636.NTE_01473	4.877e-44	169.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
YYD2_k127_5634629_0	1459636.NTE_01667	1.887e-28	117.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5634629_1	364733.XP_007803399.1	2.409e-05	54.0	KOG1565@1|root,KOG1565@2759|Eukaryota,3A7XK@33154|Opisthokonta,3PQKI@4751|Fungi,3QZRW@4890|Ascomycota,20P6K@147545|Eurotiomycetes	4751|Fungi	OW	Belongs to the peptidase M10A family	-	-	-	ko:K08002	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PG_binding_1,Peptidase_M10
YYD2_k127_5647996_0	1459636.NTE_01223	3.124e-181	578.0	COG1109@1|root,arCOG00767@2157|Archaea,41S74@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Belongs to the phosphohexose mutase family	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YYD2_k127_5647996_1	1459636.NTE_02159	4.822e-127	413.0	COG0788@1|root,arCOG02826@2157|Archaea,41S78@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Formyl transferase	-	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT_6,Formyl_trans_N
YYD2_k127_5656842_3	469382.Hbor_20910	0.0003655	51.0	arCOG02499@1|root,arCOG02499@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,NosD
YYD2_k127_5656842_2	1459636.NTE_01738	4.905e-13	70.0	COG2260@1|root,arCOG00906@2157|Archaea,41SUI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA	nop10	-	-	ko:K11130	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko03009,ko03032	-	-	-	Nop10p
YYD2_k127_5656842_0	1459636.NTE_01737	2.225e-107	353.0	COG1093@1|root,arCOG04107@2157|Archaea,41SHY@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translation initiation factor 2, alpha subunit	-	-	-	ko:K03237	ko03013,ko04138,ko04140,ko04141,ko04210,ko04932,ko05160,ko05162,ko05164,ko05168,map03013,map04138,map04140,map04141,map04210,map04932,map05160,map05162,map05164,map05168	-	-	-	ko00000,ko00001,ko03012	-	-	-	EIF_2_alpha,S1
YYD2_k127_5656842_1	1459636.NTE_01736	1.99e-58	205.0	COG2109@1|root,arCOG04678@2157|Archaea,41SFP@651137|Thaumarchaeota	651137|Thaumarchaeota	H	ATP corrinoid adenosyltransferase	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
YYD2_k127_5671330_1	1459636.NTE_03113	7.566e-142	454.0	COG0136@1|root,arCOG00494@2157|Archaea,41SFD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	aspartate-semialdehyde dehydrogenase	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YYD2_k127_5671330_0	1459636.NTE_03111	5.73e-147	469.0	COG0109@1|root,arCOG00479@2157|Archaea,41SFH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
YYD2_k127_5692184_0	1459636.NTE_01074	3.848e-12	73.0	arCOG10529@1|root,arCOG10529@2157|Archaea,41SSF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5696120_1	1459636.NTE_01414	7.1e-20	94.0	COG3269@1|root,arCOG01641@2157|Archaea	2157|Archaea	J	RNA-binding protein contains TRAM domain	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
YYD2_k127_5696120_0	1459636.NTE_02549	1.839e-20	92.0	COG1007@1|root,arCOG01540@2157|Archaea,41SDU@651137|Thaumarchaeota	651137|Thaumarchaeota	C	NADH ubiquinone oxidoreductase subunit 2 (Chain N)	-	-	1.5.98.3	ko:K22169	-	-	-	-	ko00000,ko01000	3.D.9.1	-	-	Proton_antipo_M
YYD2_k127_5697162_3	1459636.NTE_01247	4.274e-40	149.0	COG0667@1|root,arCOG01617@2157|Archaea,41S90@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD2_k127_5697162_2	1459636.NTE_01246	5.807e-44	168.0	COG1715@1|root,arCOG09740@2157|Archaea,41T5F@651137|Thaumarchaeota	651137|Thaumarchaeota	V	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
YYD2_k127_5697162_1	1459636.NTE_01245	1.864e-107	353.0	COG3253@1|root,arCOG03031@2157|Archaea,41SGX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
YYD2_k127_5697162_0	1459636.NTE_01244	8.17e-130	418.0	COG0396@1|root,arCOG04236@2157|Archaea,41SE1@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
YYD2_k127_5697162_4	1459636.NTE_01241	1.133e-20	95.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_01241|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5702599_1	1459636.NTE_01015	6.866e-20	98.0	arCOG08733@1|root,arCOG08733@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5702599_0	1459636.NTE_00963	2.653e-75	265.0	arCOG08733@1|root,arCOG08733@2157|Archaea,41SRN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_570692_1	1459636.NTE_02313	2.136e-121	401.0	COG1250@1|root,arCOG00250@2157|Archaea	2157|Archaea	I	3-hydroxyacyl-CoA dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
YYD2_k127_570692_2	1459636.NTE_02312	6.047e-103	347.0	COG1817@1|root,arCOG01395@2157|Archaea,41S8D@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
YYD2_k127_570692_0	1459636.NTE_01585	2.36e-138	456.0	COG0165@1|root,arCOG01748@2157|Archaea,41S6A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
YYD2_k127_570692_3	1459636.NTE_01588	1.281e-46	169.0	COG2151@1|root,arCOG01845@2157|Archaea,41SQV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
YYD2_k127_5713601_1	1459636.NTE_01318	1.028e-39	148.0	arCOG08720@1|root,arCOG08720@2157|Archaea,41STI@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF2024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2024
YYD2_k127_5713601_3	1459636.NTE_02015	1.056e-24	106.0	COG1698@1|root,arCOG04308@2157|Archaea,41SRP@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0147 family	-	-	-	ko:K09721	-	-	-	-	ko00000	-	-	-	UPF0147
YYD2_k127_5713601_0	1459636.NTE_03209	5.421e-59	210.0	COG1096@1|root,arCOG00676@2157|Archaea,41SQA@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs	csl4	-	-	ko:K07573	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	-
YYD2_k127_5713601_5	509191.AEDB02000073_gene1833	1.315e-13	83.0	COG1716@1|root,COG3534@1|root,COG1716@2|Bacteria,COG3534@2|Bacteria,1TS4P@1239|Firmicutes,24BY6@186801|Clostridia,3WGRR@541000|Ruminococcaceae	186801|Clostridia	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
YYD2_k127_5713601_4	1459636.NTE_02182	3.432e-22	109.0	arCOG03439@1|root,arCOG03439@2157|Archaea	2157|Archaea	L	PFAM periplasmic copper-binding	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,F5_F8_type_C
YYD2_k127_5739556_0	762051.LKI_01950	7.349e-15	85.0	COG3613@1|root,COG3613@2|Bacteria,1VEM7@1239|Firmicutes,4HXZ3@91061|Bacilli	91061|Bacilli	F	nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5744439_0	45157.CMK133CT	3.462e-11	74.0	COG1112@1|root,KOG1805@2759|Eukaryota	2759|Eukaryota	L	single-stranded DNA-dependent ATPase activity	DNA2	GO:0000002,GO:0000003,GO:0000014,GO:0000075,GO:0000076,GO:0000166,GO:0000228,GO:0000278,GO:0000706,GO:0000723,GO:0000729,GO:0000733,GO:0000781,GO:0000784,GO:0001302,GO:0001325,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003682,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005657,GO:0005694,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006264,GO:0006271,GO:0006273,GO:0006275,GO:0006281,GO:0006284,GO:0006302,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007005,GO:0007049,GO:0007568,GO:0007569,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009295,GO:0009607,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010556,GO:0010557,GO:0010604,GO:0016043,GO:0016070,GO:0016233,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016888,GO:0016890,GO:0016893,GO:0016895,GO:0017076,GO:0017108,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0022402,GO:0022414,GO:0022607,GO:0022616,GO:0030554,GO:0031297,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031570,GO:0031860,GO:0031974,GO:0031981,GO:0032042,GO:0032200,GO:0032201,GO:0032392,GO:0032502,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0033260,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0035312,GO:0035639,GO:0035861,GO:0036094,GO:0042592,GO:0042623,GO:0042645,GO:0043137,GO:0043139,GO:0043142,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043504,GO:0043596,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044786,GO:0044806,GO:0045005,GO:0045145,GO:0045740,GO:0045786,GO:0045935,GO:0046483,GO:0046700,GO:0048256,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0051276,GO:0051321,GO:0051716,GO:0051726,GO:0060249,GO:0060255,GO:0065007,GO:0065008,GO:0070013,GO:0070035,GO:0071103,GO:0071216,GO:0071495,GO:0071704,GO:0071840,GO:0071932,GO:0072396,GO:0072402,GO:0072423,GO:0072429,GO:0080090,GO:0090304,GO:0090305,GO:0090656,GO:0090734,GO:0090737,GO:0097159,GO:0097367,GO:0098687,GO:0140097,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576,GO:1902969,GO:1902990,GO:1903046,GO:1903047,GO:1903461,GO:1903469,GO:1990601,GO:2000112	2.10.1.1,2.7.7.75,3.6.4.12	ko:K10742,ko:K15376	ko00790,ko01100,ko03030,ko04727,map00790,map01100,map03030,map04727	-	R09726,R09735	RC00002,RC03462	ko00000,ko00001,ko01000,ko03032	-	-	-	AAA_11,AAA_12,Cas_Cas4,Dna2
YYD2_k127_574674_1	1459636.NTE_01088	6.511e-17	84.0	arCOG08763@1|root,arCOG08763@2157|Archaea,41SWC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_574674_0	436308.Nmar_1695	1.14e-18	87.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
YYD2_k127_576619_0	1459636.NTE_01758	5.947e-19	91.0	COG1325@1|root,arCOG01042@2157|Archaea,41SWK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA binding	-	-	-	ko:K07581	-	-	-	-	ko00000	-	-	-	RNA_binding
YYD2_k127_5766322_0	1459636.NTE_03340	8.406e-26	108.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_5775452_2	797304.Natgr_2473	2.496e-05	49.0	COG3547@1|root,arCOG03585@2157|Archaea,2XWFH@28890|Euryarchaeota,23TAM@183963|Halobacteria	183963|Halobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YYD2_k127_5775452_0	693661.Arcve_1601	5.149e-10	61.0	COG3547@1|root,arCOG03585@2157|Archaea,2XWFH@28890|Euryarchaeota	28890|Euryarchaeota	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YYD2_k127_5778090_1	1459636.NTE_01195	1.477e-20	92.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01195|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5780067_0	1459636.NTE_02879	1.717e-138	447.0	COG1243@1|root,arCOG01361@2157|Archaea,41S9N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Histone acetyltransferase	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
YYD2_k127_5780067_1	1459636.NTE_02874	1.194e-96	325.0	COG2404@1|root,arCOG00423@2157|Archaea	2157|Archaea	S	phosphohydrolase (DHH superfamily)	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	-
YYD2_k127_5780335_0	1459636.NTE_01061	4.813e-10	70.0	arCOG10358@1|root,arCOG10358@2157|Archaea,41SYI@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5794350_3	1459636.NTE_01394	1.059e-37	147.0	COG1547@1|root,arCOG03705@2157|Archaea,41SQ0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
YYD2_k127_5794350_0	1459636.NTE_03043	5.266e-159	508.0	COG1899@1|root,arCOG04142@2157|Archaea,41SWS@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
YYD2_k127_5794350_1	1459636.NTE_03041	5.012e-131	424.0	COG1899@1|root,arCOG04142@2157|Archaea,41SDB@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
YYD2_k127_5794350_2	1459636.NTE_03038	4.549e-85	286.0	COG0652@1|root,COG1287@1|root,arCOG02044@2157|Archaea,arCOG04767@2157|Archaea,41SBI@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Oligosaccharyl transferase STT3 subunit	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
YYD2_k127_5794621_0	1459636.NTE_02706	5.504e-179	571.0	COG0043@1|root,arCOG01671@2157|Archaea,41SEQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiD family decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
YYD2_k127_5794621_2	1459636.NTE_02705	2.816e-17	86.0	arCOG08790@1|root,arCOG08790@2157|Archaea,41SWN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5797793_2	1459636.NTE_00645	6.725e-28	114.0	COG2368@1|root,arCOG02143@2157|Archaea,41SA0@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Vinylacetyl-CoA Delta-isomerase	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
YYD2_k127_5797793_1	1229909.NSED_03360	1.484e-83	288.0	COG4608@1|root,arCOG00184@2157|Archaea,41S9E@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
YYD2_k127_5797793_0	1459636.NTE_01644	8.139e-93	310.0	COG1196@1|root,arCOG00371@2157|Archaea,41SDS@651137|Thaumarchaeota	651137|Thaumarchaeota	D	SMC proteins Flexible Hinge Domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YYD2_k127_5818098_0	1459636.NTE_00183	2.847e-59	220.0	COG0477@1|root,arCOG00130@2157|Archaea,arCOG00134@2157|Archaea	2157|Archaea	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
YYD2_k127_5818098_1	402777.KB235903_gene2073	1.782e-08	63.0	COG0515@1|root,COG5435@1|root,COG0515@2|Bacteria,COG5435@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H9KR@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD2_k127_5818523_0	1459636.NTE_01508	1.063e-44	165.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5818523_1	1229909.NSED_08795	1.046e-17	89.0	COG3794@1|root,arCOG02929@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
YYD2_k127_5820245_2	518766.Rmar_1800	9.694e-108	361.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1FITC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
YYD2_k127_5820245_6	1459636.NTE_03026	1.364e-25	109.0	arCOG08645@1|root,arCOG08645@2157|Archaea,41STW@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5820245_3	1459636.NTE_01654	3.553e-39	149.0	COG1990@1|root,arCOG04228@2157|Archaea,41ST1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Peptidyl-tRNA hydrolase PTH2	-	-	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
YYD2_k127_5820245_1	1459636.NTE_01655	5.73e-122	405.0	COG0644@1|root,arCOG00570@2157|Archaea,41SB5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5820245_4	1459636.NTE_01656	7.927e-30	119.0	COG2888@1|root,arCOG01989@2157|Archaea,41T83@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Zn-ribbon RNA-binding protein with a function in translation	-	-	-	ko:K07580	-	-	-	-	ko00000	-	-	-	-
YYD2_k127_5820245_5	1459636.NTE_01657	1.234e-25	110.0	COG2092@1|root,arCOG01988@2157|Archaea,41SS1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA	ef1b	-	-	ko:K03232	-	-	-	-	ko00000,ko03012	-	-	-	EF1_GNE
YYD2_k127_5820245_7	1459636.NTE_01660	8.562e-20	90.0	arCOG07192@1|root,arCOG07192@2157|Archaea,41SVA@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5820245_0	1459636.NTE_01661	3.609e-145	464.0	COG0109@1|root,arCOG00479@2157|Archaea,41SDQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
YYD2_k127_583902_1	1459636.NTE_02136	1.145e-15	78.0	arCOG12348@1|root,arCOG12348@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5863646_0	1459636.NTE_03190	3.002e-87	296.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YYD2_k127_5886540_0	1459636.NTE_02923	1.486e-76	262.0	COG2226@1|root,arCOG04348@2157|Archaea,41SGQ@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
YYD2_k127_5886540_1	1459636.NTE_01424	8.604e-28	116.0	COG1146@1|root,arCOG08753@1|root,arCOG04548@2157|Archaea,arCOG08753@2157|Archaea,41SH5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
YYD2_k127_589240_1	161528.ED21_23756	1.351e-06	52.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2U31V@28211|Alphaproteobacteria,2K3PY@204457|Sphingomonadales	204457|Sphingomonadales	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_589240_0	1123058.KB894281_gene1833	3e-09	65.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1HX98@117743|Flavobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
YYD2_k127_5896829_3	694429.Pyrfu_0217	1.06e-14	75.0	COG1958@1|root,arCOG00998@2157|Archaea,2XR0V@28889|Crenarchaeota	28889|Crenarchaeota	K	PFAM Like-Sm ribonucleoprotein, core	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
YYD2_k127_5896829_2	1459636.NTE_02685	2.334e-34	136.0	COG1786@1|root,arCOG04279@2157|Archaea,41SPA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
YYD2_k127_5896829_0	1459636.NTE_02684	1.563e-130	426.0	COG1679@1|root,arCOG04278@2157|Archaea,41SBC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
YYD2_k127_5896829_1	1459636.NTE_03217	4.571e-86	289.0	COG1634@1|root,arCOG04303@2157|Archaea,41SKX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP)	mptE	-	2.7.6.3	ko:K07142	ko00790,map00790	-	R03503	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	MAF_flag10
YYD2_k127_5902845_1	1006006.Mcup_1708	5.122e-65	230.0	COG1012@1|root,arCOG01252@2157|Archaea,2XRM8@28889|Crenarchaeota	28889|Crenarchaeota	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
YYD2_k127_5902845_0	1459636.NTE_01521	2.914e-139	453.0	COG0160@1|root,arCOG00915@2157|Archaea,41TBD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.76	ko:K00823,ko:K00836	ko00250,ko00260,ko00410,ko00640,ko00650,ko01100,ko01120,ko01210,ko01230,map00250,map00260,map00410,map00640,map00650,map01100,map01120,map01210,map01230	M00027,M00033	R00908,R01648,R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YYD2_k127_5902845_2	1459636.NTE_00036	6.764e-56	201.0	COG0494@1|root,arCOG01073@2157|Archaea	2157|Archaea	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
YYD2_k127_5917967_1	1459636.NTE_02770	2.362e-30	123.0	arCOG11305@1|root,arCOG11305@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5917967_0	1459636.NTE_03048	1.722e-67	237.0	COG1938@1|root,arCOG00347@2157|Archaea,41T2Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
YYD2_k127_5917967_3	1123489.AUAN01000003_gene1135	9.787e-05	45.0	COG0596@1|root,COG0596@2|Bacteria,1V18E@1239|Firmicutes	1239|Firmicutes	S	Alpha/beta hydrolase family	-	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
YYD2_k127_5938945_5	716928.AJQT01000012_gene17	3.354e-18	86.0	COG4274@1|root,COG4274@2|Bacteria,1N29P@1224|Proteobacteria,2UD2U@28211|Alphaproteobacteria,4BKYH@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
YYD2_k127_5938945_4	315749.Bcer98_1409	2.443e-18	87.0	COG4447@1|root,COG4447@2|Bacteria,1UU3Y@1239|Firmicutes,4HCEG@91061|Bacilli	91061|Bacilli	S	cellulose binding	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR
YYD2_k127_5938945_0	485913.Krac_2295	2.988e-73	254.0	COG4447@1|root,COG4447@2|Bacteria,2G8DW@200795|Chloroflexi	200795|Chloroflexi	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5938945_3	1463825.JNXC01000031_gene1602	6.689e-22	102.0	COG1853@1|root,COG1853@2|Bacteria,2IE1Z@201174|Actinobacteria	201174|Actinobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
YYD2_k127_5938945_1	1405.DJ92_5035	9.036e-31	125.0	2DNMG@1|root,32Y46@2|Bacteria,1VK1T@1239|Firmicutes,4HNYW@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5938945_2	1274374.CBLK010000053_gene2345	2.216e-30	128.0	COG2345@1|root,COG2345@2|Bacteria,1V5Q5@1239|Firmicutes,4HHMX@91061|Bacilli,26U3B@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,HTH_DeoR
YYD2_k127_5938945_6	335543.Sfum_2943	4.471e-11	68.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,dCache_1
YYD2_k127_5938945_7	589865.DaAHT2_0874	0.0003485	46.0	COG0745@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_8,PAS_9,Response_reg,sCache_2
YYD2_k127_5940567_1	1459636.NTE_03327	1.098e-17	91.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5940567_0	716544.wcw_0742	7.339e-46	171.0	COG1090@1|root,COG1090@2|Bacteria,2JFV6@204428|Chlamydiae	204428|Chlamydiae	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
YYD2_k127_5948386_0	1459636.NTE_01785	2.638e-231	721.0	COG0498@1|root,arCOG01434@2157|Archaea,41S5N@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD2_k127_5948386_1	1459636.NTE_01786	1.924e-32	128.0	arCOG08697@1|root,arCOG08697@2157|Archaea,41SUN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5962901_4	1459636.NTE_03208	1.381e-10	62.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
YYD2_k127_5962901_0	1459636.NTE_02319	0.0	1094.0	COG1964@1|root,arCOG00933@2157|Archaea,41SAY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Radical SAM	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
YYD2_k127_5962901_1	1459636.NTE_02211	6.615e-131	423.0	COG1250@1|root,arCOG00249@2157|Archaea	2157|Archaea	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.116,4.2.1.17	ko:K01715,ko:K15019	ko00650,ko00720,ko01120,ko01200,map00650,map00720,map01120,map01200	M00375	R03026,R03045	RC00831,RC00834	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YYD2_k127_5962901_2	1459636.NTE_02212	1.432e-99	334.0	COG0083@1|root,arCOG01027@2157|Archaea,41S89@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YYD2_k127_5962901_3	1459636.NTE_02213	4.477e-98	326.0	COG1100@1|root,arCOG01225@2157|Archaea,41T0A@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	ATP_bind_1
YYD2_k127_5974930_5	1459636.NTE_00004	1.414e-08	59.0	COG0468@1|root,arCOG00415@2157|Archaea	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	-	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
YYD2_k127_5974930_6	1459636.NTE_00005	7.034e-06	51.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5974930_3	1459636.NTE_00006	5.312e-17	83.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5974930_1	1459636.NTE_00007	1.154e-42	166.0	COG0417@1|root,arCOG00329@2157|Archaea	2157|Archaea	L	DNA polymerase elongation subunit (Family B)	polB2	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B
YYD2_k127_5974930_0	1459636.NTE_00007	9.949e-161	520.0	COG0417@1|root,arCOG00329@2157|Archaea	2157|Archaea	L	DNA polymerase elongation subunit (Family B)	polB2	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B
YYD2_k127_5974930_4	1459636.NTE_02412	7.432e-15	77.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_5974930_2	247490.KSU1_D0999	1.486e-25	120.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
YYD2_k127_5986153_0	1459636.NTE_01247	1.112e-160	511.0	COG0667@1|root,arCOG01617@2157|Archaea,41S90@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD2_k127_600186_0	526225.Gobs_1201	1.526e-94	321.0	28KG6@1|root,2ZA22@2|Bacteria,2IKCI@201174|Actinobacteria	201174|Actinobacteria	S	PvdJ PvdD PvdP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6003207_0	1459636.NTE_02780	6.044e-118	389.0	COG1641@1|root,arCOG02701@2157|Archaea,41SDC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF111	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
YYD2_k127_6033332_2	153948.NAL212_2691	2.337e-48	181.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2VJF5@28216|Betaproteobacteria,372Q6@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NADPH-dependent FMN reductase	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
YYD2_k127_6033332_0	1459636.NTE_00844	4.873e-78	269.0	COG1335@1|root,arCOG01943@2157|Archaea	2157|Archaea	Q	COG1335 Amidases related to nicotinamidase	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
YYD2_k127_6033332_1	1459636.NTE_03464	1.849e-66	237.0	COG1752@1|root,arCOG09020@2157|Archaea	2157|Archaea	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
YYD2_k127_6046701_6	1459636.NTE_01091	1.363e-95	318.0	COG0468@1|root,arCOG00415@2157|Archaea,41SBA@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
YYD2_k127_6046701_8	1459636.NTE_01383	2.528e-79	270.0	COG1648@1|root,arCOG01044@2157|Archaea,41SN9@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Siroheme synthase	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
YYD2_k127_6046701_3	1459636.NTE_01382	6.699e-139	453.0	COG0373@1|root,arCOG01036@2157|Archaea,41SDM@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	-	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
YYD2_k127_6046701_4	1131266.ARWQ01000005_gene821	1.505e-120	396.0	COG0113@1|root,arCOG04300@2157|Archaea,41SET@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
YYD2_k127_6046701_2	1459636.NTE_01013	8.837e-169	540.0	COG0001@1|root,arCOG00918@2157|Archaea,41SDE@651137|Thaumarchaeota	651137|Thaumarchaeota	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YYD2_k127_6046701_5	1459636.NTE_01012	2.471e-100	336.0	COG0181@1|root,arCOG04299@2157|Archaea,41S6Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
YYD2_k127_6046701_7	436308.Nmar_0492	1.399e-88	298.0	COG0007@1|root,arCOG00644@2157|Archaea,41S9J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
YYD2_k127_6046701_14	192952.MM_0308	6.938e-06	57.0	COG1587@1|root,arCOG02048@2157|Archaea,2XTA1@28890|Euryarchaeota,2NBJR@224756|Methanomicrobia	224756|Methanomicrobia	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
YYD2_k127_6046701_0	1459636.NTE_02649	1.966e-279	861.0	COG0719@1|root,arCOG01715@2157|Archaea,41S5W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
YYD2_k127_6046701_1	1459636.NTE_02650	1.505e-174	559.0	COG0719@1|root,arCOG01715@2157|Archaea,41S7W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufD	-	-	-	ko:K09014,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
YYD2_k127_6046701_12	1459636.NTE_02651	5.32e-33	130.0	COG2146@1|root,arCOG02852@2157|Archaea,41T71@651137|Thaumarchaeota	651137|Thaumarchaeota	P	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
YYD2_k127_6046701_9	436308.Nmar_0635	7.094e-74	258.0	COG2084@1|root,arCOG00247@2157|Archaea,41SI2@651137|Thaumarchaeota	651137|Thaumarchaeota	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
YYD2_k127_6046701_13	1459636.NTE_02641	4.806e-31	126.0	COG0073@1|root,arCOG01136@2157|Archaea,41SSY@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Putative tRNA binding domain	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
YYD2_k127_6046701_11	1459636.NTE_01359	4.552e-37	147.0	arCOG03737@1|root,arCOG03737@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6046701_10	1459636.NTE_01360	4.397e-39	150.0	COG0640@1|root,arCOG00472@2157|Archaea	2157|Archaea	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_16,AAA_22,DUF2791,HTH_5
YYD2_k127_6049064_0	1042377.AFPJ01000051_gene33	3.073e-71	251.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD2_k127_6049812_0	1229909.NSED_02125	2.381e-43	165.0	COG0517@1|root,arCOG00601@2157|Archaea	2157|Archaea	C	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_607198_1	1459636.NTE_01493	5.532e-50	191.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YYD2_k127_607198_0	1459636.NTE_01315	1.311e-67	235.0	COG0778@1|root,arCOG00288@2157|Archaea	2157|Archaea	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YYD2_k127_607198_4	266117.Rxyl_1054	2.613e-10	61.0	COG0400@1|root,COG0400@2|Bacteria,2INMY@201174|Actinobacteria,4CTAJ@84995|Rubrobacteria	84995|Rubrobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	DLH
YYD2_k127_607198_3	485913.Krac_9105	1.369e-11	66.0	COG0400@1|root,COG0400@2|Bacteria,2G7EK@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
YYD2_k127_607198_5	1027292.HMPREF9372_1737	4.617e-06	50.0	COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli,26EXH@186818|Planococcaceae	91061|Bacilli	S	Carboxylesterase	yahD	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,DLH
YYD2_k127_60735_0	383372.Rcas_4230	3.375e-05	50.0	COG3548@1|root,COG3548@2|Bacteria,2G9XI@200795|Chloroflexi,377QW@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
YYD2_k127_6099255_1	1459636.NTE_03542	3.259e-23	101.0	COG3432@1|root,arCOG01063@2157|Archaea,41T7S@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_6099255_0	1459636.NTE_03541	2.407e-25	110.0	arCOG11425@1|root,arCOG11425@2157|Archaea,41T5C@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6099255_2	1229909.NSED_08805	1.157e-19	89.0	COG3794@1|root,arCOG02929@2157|Archaea,41T61@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
YYD2_k127_6101600_0	1459636.NTE_01164	8.292e-18	85.0	arCOG00144@1|root,arCOG11894@1|root,arCOG00144@2157|Archaea,arCOG11894@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD2_k127_6101743_0	186497.PF1731	5.111e-131	432.0	COG0541@1|root,arCOG01228@2157|Archaea,2XTWX@28890|Euryarchaeota,24377@183968|Thermococci	183968|Thermococci	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	srp54	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
YYD2_k127_6101743_2	1131266.ARWQ01000005_gene839	1.139e-67	237.0	COG2102@1|root,arCOG00035@2157|Archaea,41SHD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Diphthamide synthase	-	-	6.3.1.14	ko:K06927	-	-	R03613	RC00358	ko00000,ko01000,ko03012	-	-	-	Diphthami_syn_2
YYD2_k127_6101743_3	1459636.NTE_01573	3.721e-06	52.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_6101743_1	1459636.NTE_00762	5.336e-89	297.0	COG1064@1|root,arCOG01455@2157|Archaea,41SA9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_6125438_0	1459636.NTE_00118	1.141e-29	121.0	COG2146@1|root,arCOG02852@2157|Archaea	2157|Archaea	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
YYD2_k127_61461_1	1459636.NTE_00969	1.38e-110	363.0	COG0182@1|root,arCOG01123@2157|Archaea,41SF9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
YYD2_k127_61461_0	1459636.NTE_00968	5.039e-168	539.0	COG0677@1|root,arCOG00252@2157|Archaea	2157|Archaea	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wecC	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YYD2_k127_6157198_0	1459636.NTE_01284	3.485e-304	953.0	COG0495@1|root,arCOG00809@2157|Archaea,41SES@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
YYD2_k127_6157345_0	1158602.I590_03390	1.098e-06	57.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,4B1MN@81852|Enterococcaceae	91061|Bacilli	T	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
YYD2_k127_6165869_7	1459636.NTE_00454	2.48e-50	181.0	COG1308@1|root,arCOG04061@2157|Archaea,41SNN@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Contacts the emerging nascent chain on the ribosome	nac	-	-	ko:K03626	-	-	-	-	ko00000	-	-	-	NAC
YYD2_k127_6165869_8	1459636.NTE_00453	3.447e-49	180.0	COG1370@1|root,arCOG00991@2157|Archaea,41SP1@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Patch-forming domain C2 of tRNA-guanine transglycosylase	-	-	-	ko:K07398	-	-	-	-	ko00000	-	-	-	PUA,TGT_C2
YYD2_k127_6165869_10	1459636.NTE_00450	2.2e-35	140.0	COG1813@1|root,arCOG01863@2157|Archaea	2157|Archaea	K	transcription factor, homolog of eukaryotic MBF1	-	-	-	ko:K03627	-	-	-	-	ko00000	-	-	-	HTH_3
YYD2_k127_6165869_3	1459636.NTE_00449	1.011e-125	412.0	COG2262@1|root,arCOG00353@2157|Archaea,41SD4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YYD2_k127_6165869_6	1459636.NTE_00448	2.489e-59	210.0	COG1303@1|root,arCOG01857@2157|Archaea,41SIR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs	-	-	2.1.1.206	ko:K07254	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Trm56
YYD2_k127_6165869_0	1459636.NTE_03053	2.621e-285	887.0	COG0155@1|root,arCOG02055@2157|Archaea,41S5Q@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Sulfite reductase	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
YYD2_k127_6165869_4	1459636.NTE_03054	3.782e-124	406.0	COG2897@1|root,arCOG02019@2157|Archaea,41SBN@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
YYD2_k127_6165869_9	1459636.NTE_01031	2.82e-38	147.0	COG0071@1|root,arCOG01832@2157|Archaea,41T74@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
YYD2_k127_6165869_2	1459636.NTE_01017	2.038e-135	443.0	COG0585@1|root,arCOG04252@2157|Archaea,41S7C@651137|Thaumarchaeota	651137|Thaumarchaeota	J	tRNA pseudouridine synthase	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
YYD2_k127_6165869_11	1459636.NTE_00455	1.094e-17	87.0	COG2811@1|root,arCOG03363@2157|Archaea,41TA7@651137|Thaumarchaeota	651137|Thaumarchaeota	C	H subunit	-	-	-	ko:K02107	ko00190,map00190	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
YYD2_k127_6165869_5	1459636.NTE_03272	4.61e-96	325.0	COG1527@1|root,arCOG02459@2157|Archaea,41T18@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP synthase (C/AC39) subunit	-	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
YYD2_k127_6165869_1	1459636.NTE_01317	8.842e-183	579.0	COG1171@1|root,arCOG01431@2157|Archaea,41SCU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD2_k127_6169615_0	1459636.NTE_00905	2.782e-87	293.0	COG1814@1|root,arCOG01096@2157|Archaea,41T0M@651137|Thaumarchaeota	651137|Thaumarchaeota	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
YYD2_k127_6169615_1	1121091.AUMP01000005_gene1738	6.696e-14	77.0	COG2133@1|root,COG2133@2|Bacteria,1VBUK@1239|Firmicutes,4HKNP@91061|Bacilli	91061|Bacilli	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
YYD2_k127_6169615_2	1415778.JQMM01000001_gene98	0.0001392	50.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1J50B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
YYD2_k127_6169880_0	521011.Mpal_1474	2.027e-75	268.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
YYD2_k127_6169880_1	1459636.NTE_01932	2.787e-69	253.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
YYD2_k127_6179008_1	1459636.NTE_01292	3.133e-126	414.0	COG0552@1|root,arCOG01227@2157|Archaea,41SCC@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
YYD2_k127_6179008_2	1459636.NTE_01291	2.153e-41	156.0	COG1730@1|root,arCOG01341@2157|Archaea,41SSP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdA	-	-	ko:K04797	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin
YYD2_k127_6179008_0	1459636.NTE_01288	8.724e-159	506.0	COG0644@1|root,arCOG00570@2157|Archaea,41SCG@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
YYD2_k127_6179008_3	1459636.NTE_01284	2.418e-29	122.0	COG0495@1|root,arCOG00809@2157|Archaea,41SES@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
YYD2_k127_6181425_0	1382306.JNIM01000001_gene3000	7.293e-73	257.0	COG2141@1|root,COG2141@2|Bacteria,2G873@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
YYD2_k127_6181425_1	1304885.AUEY01000094_gene3533	2.599e-69	255.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,42MW8@68525|delta/epsilon subdivisions,2WKI6@28221|Deltaproteobacteria,2MIK1@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
YYD2_k127_6181425_3	1094980.Mpsy_2342	2.019e-29	134.0	COG0467@1|root,arCOG01178@2157|Archaea,2Y0GM@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM GvpD gas vesicle	gvpD	-	-	-	-	-	-	-	-	-	-	-	GvpD
YYD2_k127_6181425_4	1229909.NSED_04685	9.206e-29	126.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
YYD2_k127_6181425_2	1121430.JMLG01000002_gene1312	3.901e-32	130.0	COG1926@1|root,COG1926@2|Bacteria,1V256@1239|Firmicutes,249BZ@186801|Clostridia,2623X@186807|Peptococcaceae	186801|Clostridia	F	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
YYD2_k127_6188231_0	1278073.MYSTI_04495	8.115e-07	52.0	2EYGB@1|root,33RQ8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6188332_0	1459636.NTE_02515	1.219e-10	64.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
YYD2_k127_6202245_0	262724.TT_C1879	1.143e-44	180.0	COG0433@1|root,COG0433@2|Bacteria,1WME2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6218205_2	1459636.NTE_01446	2.539e-69	246.0	arCOG04054@1|root,arCOG04054@2157|Archaea,41SIQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6218205_4	1459636.NTE_02337	1.766e-45	169.0	COG1430@1|root,arCOG03116@2157|Archaea,41SP3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
YYD2_k127_6218205_0	1459636.NTE_02371	3.4e-307	952.0	COG0365@1|root,arCOG01529@2157|Archaea,41S8Z@651137|Thaumarchaeota	651137|Thaumarchaeota	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YYD2_k127_6218205_5	1459636.NTE_02412	6.347e-18	86.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_6218205_3	1459636.NTE_00070	2.739e-61	211.0	COG1145@1|root,arCOG00291@2157|Archaea,41SNB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	NADH ubiquinone oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
YYD2_k127_6218205_1	1459636.NTE_01444	9.066e-224	705.0	COG1351@1|root,arCOG01884@2157|Archaea,41SF6@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
YYD2_k127_6218205_6	1131266.ARWQ01000002_gene630	2.603e-15	78.0	COG0258@1|root,arCOG04050@2157|Archaea,41SBU@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
YYD2_k127_6218398_1	1459636.NTE_00549	2.083e-62	216.0	COG0229@1|root,arCOG02815@2157|Archaea	2157|Archaea	O	COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
YYD2_k127_6218398_0	1459636.NTE_00548	6.411e-81	271.0	COG0225@1|root,arCOG02816@2157|Archaea,41SMP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
YYD2_k127_6221060_1	436308.Nmar_1146	4.583e-35	140.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	2157|Archaea	O	Trypsin-like serine protease with C-terminal PDZ domain	degP	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YYD2_k127_6221060_0	1459636.NTE_01001	1.705e-65	238.0	arCOG10517@1|root,arCOG10517@2157|Archaea,41T0I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6232903_2	398767.Glov_0114	0.0005913	44.0	COG0500@1|root,COG2226@2|Bacteria,1QZV0@1224|Proteobacteria,43CPF@68525|delta/epsilon subdivisions,2WS28@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD2_k127_6232903_0	396588.Tgr7_2351	2.148e-28	123.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_11,Methyltransf_12,Methyltransf_2,Methyltransf_23
YYD2_k127_6232903_1	1459636.NTE_00145	1.003e-21	99.0	arCOG03593@1|root,arCOG03593@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795,PRC
YYD2_k127_6233868_7	1459636.NTE_00772	4.859e-102	337.0	COG0601@1|root,arCOG00751@2157|Archaea,41S7B@651137|Thaumarchaeota	651137|Thaumarchaeota	P	inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
YYD2_k127_6233868_2	1459636.NTE_00771	4.009e-169	545.0	COG1173@1|root,arCOG00749@2157|Archaea,41SFE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
YYD2_k127_6233868_17	118168.MC7420_3051	4.859e-33	140.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
YYD2_k127_6233868_16	1459636.NTE_01615	8.244e-36	138.0	arCOG08751@1|root,arCOG08751@2157|Archaea,41SS7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6233868_14	1459636.NTE_01618	1.184e-50	183.0	COG1310@1|root,arCOG01139@2157|Archaea,41SQ7@651137|Thaumarchaeota	651137|Thaumarchaeota	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
YYD2_k127_6233868_3	1459636.NTE_00624	3.763e-127	419.0	COG1498@1|root,arCOG01923@2157|Archaea,41SY9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	NOSIC (NUC001) domain	-	-	-	ko:K14564	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	Nop
YYD2_k127_6233868_8	1459636.NTE_00625	1.253e-96	321.0	COG0513@1|root,arCOG00078@2157|Archaea,41SM2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA	flpA	-	-	ko:K04795	-	-	-	-	ko00000,ko03009	-	-	-	Fibrillarin
YYD2_k127_6233868_12	1459636.NTE_00626	2.891e-57	207.0	COG0164@1|root,arCOG04121@2157|Archaea,41SK9@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YYD2_k127_6233868_4	1459636.NTE_00628	3.281e-116	387.0	COG1867@1|root,arCOG01219@2157|Archaea,41SAG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family	-	-	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
YYD2_k127_6233868_5	1459636.NTE_02997	7.207e-113	369.0	COG1116@1|root,arCOG00193@2157|Archaea,41S6Q@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
YYD2_k127_6233868_10	1459636.NTE_02998	8.462e-68	238.0	COG0685@1|root,arCOG00475@2157|Archaea,41SNK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	cytochrome-c peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6233868_15	1459636.NTE_03007	5.652e-36	144.0	COG0494@1|root,arCOG01072@2157|Archaea,41STX@651137|Thaumarchaeota	651137|Thaumarchaeota	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD2_k127_6233868_1	1229909.NSED_02815	8.333e-221	693.0	COG0043@1|root,arCOG01671@2157|Archaea,41S94@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiD family decarboxylase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
YYD2_k127_6233868_13	1459636.NTE_03122	8.603e-52	186.0	COG5496@1|root,arCOG04331@2157|Archaea	2157|Archaea	S	thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
YYD2_k127_6233868_0	1459636.NTE_03123	1.296e-275	856.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
YYD2_k127_6233868_9	1229909.NSED_09940	5.641e-77	266.0	COG0463@1|root,arCOG00894@2157|Archaea,41SAS@651137|Thaumarchaeota	651137|Thaumarchaeota	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
YYD2_k127_6233868_6	1459636.NTE_01730	5.212e-104	356.0	arCOG04615@1|root,arCOG04615@2157|Archaea	2157|Archaea	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_6233868_11	1459636.NTE_01932	1.628e-64	235.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
YYD2_k127_6241848_2	1459636.NTE_01462	2.348e-65	237.0	arCOG08742@1|root,arCOG08742@2157|Archaea,41SS8@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6241848_1	436308.Nmar_0626	6.514e-97	325.0	COG0391@1|root,arCOG04395@2157|Archaea,41SCH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
YYD2_k127_6241848_3	1459636.NTE_01464	9.679e-40	155.0	COG1920@1|root,arCOG04472@2157|Archaea,41SPV@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Guanylyl transferase CofC like	-	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
YYD2_k127_6241848_0	1459636.NTE_03106	3.308e-192	605.0	COG0604@1|root,arCOG01458@2157|Archaea,41SZ9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_6241848_4	1131266.ARWQ01000009_gene916	5.501e-12	69.0	COG2301@1|root,arCOG00760@2157|Archaea,41S6F@651137|Thaumarchaeota	651137|Thaumarchaeota	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
YYD2_k127_6268984_1	253839.SSNG_05424	2.034e-06	58.0	2F3TC@1|root,33WJS@2|Bacteria,2IIQF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6274985_0	1459636.NTE_01052	5.156e-76	267.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
YYD2_k127_6280309_1	1459636.NTE_01838	2.415e-85	287.0	arCOG08717@1|root,arCOG08717@2157|Archaea,41SFQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD2_k127_6280309_3	1459636.NTE_01837	4.129e-63	227.0	COG2106@1|root,arCOG04069@2157|Archaea,41SI7@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Putative RNA methyltransferase	-	-	-	ko:K09142	-	-	-	-	ko00000	-	-	-	Methyltrn_RNA_3
YYD2_k127_6280309_0	1459636.NTE_01836	2.11e-135	439.0	COG0087@1|root,arCOG04070@2157|Archaea,41SDN@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein L3	-	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
YYD2_k127_6280309_2	1459636.NTE_01835	4.77e-70	241.0	COG0469@1|root,arCOG04071@2157|Archaea,41SHB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein L4	-	-	-	ko:K02930	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YYD2_k127_6285558_0	1122138.AQUZ01000019_gene8188	1.161e-10	71.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD2_k127_6287730_0	909663.KI867149_gene3449	4.064e-38	146.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,42U37@68525|delta/epsilon subdivisions,2WQ9M@28221|Deltaproteobacteria,2MRZA@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
YYD2_k127_6287730_2	886293.Sinac_1574	9.321e-15	76.0	COG2146@1|root,COG2146@2|Bacteria,2J0ZZ@203682|Planctomycetes	203682|Planctomycetes	P	COG2146 Ferredoxin subunits of nitrite reductase and	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
YYD2_k127_6295060_0	1459636.NTE_01638	1.589e-128	422.0	COG1602@1|root,arCOG04269@2157|Archaea,41S7H@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Archaeal Nre, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nre_C,Nre_N
YYD2_k127_6295060_1	1459636.NTE_03060	5.06e-108	358.0	COG1131@1|root,arCOG00196@2157|Archaea,41S73@651137|Thaumarchaeota	651137|Thaumarchaeota	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YYD2_k127_6296585_1	1229909.NSED_01240	1.792e-30	124.0	COG0483@1|root,arCOG01349@2157|Archaea,41SIF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YYD2_k127_6296585_0	1459636.NTE_01553	2.695e-34	134.0	arCOG12283@1|root,arCOG12283@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6296585_2	144197.XP_008305176.1	3.475e-07	60.0	KOG1565@1|root,KOG1565@2759|Eukaryota,38CRR@33154|Opisthokonta,3B9IY@33208|Metazoa,3CT1E@33213|Bilateria,481TV@7711|Chordata,496SD@7742|Vertebrata,49XMF@7898|Actinopterygii	33208|Metazoa	OW	Matrix metallopeptidase 19	MMP19	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022617,GO:0030198,GO:0031012,GO:0043062,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564	3.4.24.80	ko:K07763,ko:K07998	ko04668,ko04912,map04668,map04912	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hemopexin,PG_binding_1,Peptidase_M10
YYD2_k127_6300584_0	1150621.SMUL_1510	3.179e-16	91.0	COG0420@1|root,COG0420@2|Bacteria,1Q58G@1224|Proteobacteria,42NPZ@68525|delta/epsilon subdivisions,2YNJW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
YYD2_k127_6300584_1	224324.aq_1006	9.304e-06	59.0	COG0419@1|root,COG0419@2|Bacteria,2G46J@200783|Aquificae	200783|Aquificae	L	PFAM SMC domain protein	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_21,AAA_23,Rad50_zn_hook,SMC_N,SbcCD_C
YYD2_k127_6306354_0	1403313.AXBR01000023_gene2644	9.305e-57	207.0	COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli,1ZD11@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	gdh	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
YYD2_k127_6306354_1	1459636.NTE_00644	2.175e-44	168.0	arCOG07179@1|root,arCOG07179@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6306354_2	1048834.TC41_0139	6.062e-40	159.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,278QY@186823|Alicyclobacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
YYD2_k127_6308061_0	1349822.NSB1T_07500	4.572e-43	172.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,2FNZW@200643|Bacteroidia,22XA9@171551|Porphyromonadaceae	976|Bacteroidetes	C	NADH dehydrogenase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YYD2_k127_6318480_0	1459636.NTE_02247	2.028e-47	171.0	COG0535@1|root,arCOG00938@2157|Archaea,41SXS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
YYD2_k127_6318480_1	1121468.AUBR01000024_gene3040	0.0002172	51.0	COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,24QQ6@186801|Clostridia,42H8S@68295|Thermoanaerobacterales	186801|Clostridia	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD2_k127_6334587_0	926549.KI421517_gene781	2.57e-88	296.0	COG0693@1|root,COG0693@2|Bacteria,4NGII@976|Bacteroidetes,47K2N@768503|Cytophagia	976|Bacteroidetes	C	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
YYD2_k127_6334587_1	1459636.NTE_01000	2.514e-33	135.0	COG1309@1|root,arCOG02643@2157|Archaea	2157|Archaea	K	PFAM regulatory protein TetR	-	-	-	ko:K03577,ko:K18939	-	M00647,M00715	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_2,TetR_C_6,TetR_N
YYD2_k127_6343924_2	1459636.NTE_03016	1.22e-105	354.0	COG0018@1|root,arCOG00487@2157|Archaea,41SAI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YYD2_k127_6343924_3	1459636.NTE_03017	7.196e-94	313.0	COG0561@1|root,arCOG01213@2157|Archaea,41SIV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Phosphoglycolate phosphatase	-	-	3.1.3.18	ko:K22223	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
YYD2_k127_6343924_1	1459636.NTE_01993	6.86e-237	739.0	COG0034@1|root,arCOG00093@2157|Archaea,41S7N@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
YYD2_k127_6343924_0	1459636.NTE_01994	2.537e-281	882.0	COG0046@1|root,arCOG00641@2157|Archaea,41S6S@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YYD2_k127_6343924_5	1459636.NTE_01995	2.856e-90	302.0	COG0047@1|root,arCOG00102@2157|Archaea,41SG3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
YYD2_k127_6343924_6	1459636.NTE_01996	3.296e-46	170.0	COG0517@1|root,arCOG00606@2157|Archaea,41SRY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YYD2_k127_6343924_7	1459636.NTE_01997	8.889e-23	100.0	COG1828@1|root,arCOG04462@2157|Archaea,41STY@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
YYD2_k127_6343924_4	1459636.NTE_02000	3.316e-93	313.0	COG0842@1|root,arCOG01469@2157|Archaea	2157|Archaea	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
YYD2_k127_6350834_0	1459636.NTE_00795	1.113e-46	171.0	COG1055@1|root,arCOG00238@2157|Archaea,41SXH@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
YYD2_k127_6354129_0	1227453.C444_17158	1.646e-08	58.0	arCOG11507@1|root,arCOG11507@2157|Archaea,2XXTV@28890|Euryarchaeota,23WCS@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6354585_7	1267534.KB906761_gene1197	4.943e-45	183.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Lactonase,VCBS
YYD2_k127_6354585_5	1459636.NTE_02860	9.885e-69	239.0	COG2860@1|root,arCOG04641@2157|Archaea,41SIS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
YYD2_k127_6354585_6	1229909.NSED_08245	6.509e-47	172.0	arCOG08677@1|root,arCOG08677@2157|Archaea,41SVJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6354585_3	1123288.SOV_5c03880	9.93e-86	292.0	COG1082@1|root,COG1082@2|Bacteria,1TSIG@1239|Firmicutes	1239|Firmicutes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD2_k127_6354585_1	436308.Nmar_1390	1.391e-104	348.0	COG0167@1|root,arCOG00603@2157|Archaea	2157|Archaea	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.1,1.3.1.14,1.3.5.2,1.3.98.1	ko:K00226,ko:K00254,ko:K17723,ko:K17828	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R01868,R01869,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YYD2_k127_6354585_4	1131266.ARWQ01000004_gene1493	1.234e-82	282.0	COG0543@1|root,arCOG02199@2157|Archaea,41SY5@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
YYD2_k127_6354585_2	1459636.NTE_02661	3.181e-104	355.0	COG1254@1|root,arCOG00643@2157|Archaea	2157|Archaea	C	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Acylphosphatase
YYD2_k127_6354585_0	1459636.NTE_02662	1.585e-110	363.0	COG0175@1|root,arCOG00124@2157|Archaea,41S9Q@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YYD2_k127_635822_2	1459636.NTE_01071	7.383e-20	90.0	COG1378@1|root,arCOG02037@2157|Archaea	2157|Archaea	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
YYD2_k127_635822_0	1459636.NTE_01070	1.7e-37	145.0	arCOG10535@1|root,arCOG10535@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_635822_1	1459636.NTE_00395	8.08e-35	138.0	arCOG06267@1|root,arCOG06267@2157|Archaea	2157|Archaea	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6366382_0	247490.KSU1_C1274	6.102e-29	132.0	COG1409@1|root,COG3534@1|root,COG1409@2|Bacteria,COG3534@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
YYD2_k127_6367343_1	1459636.NTE_00105	1.383e-43	163.0	COG1545@1|root,arCOG01285@2157|Archaea,41SQK@651137|Thaumarchaeota	651137|Thaumarchaeota	V	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
YYD2_k127_6367343_2	1459636.NTE_00108	3.785e-35	142.0	COG5491@1|root,arCOG00452@2157|Archaea	2157|Archaea	N	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	Snf7
YYD2_k127_6367343_0	436308.Nmar_1628	1.162e-183	598.0	COG0640@1|root,COG1328@1|root,arCOG00734@2157|Archaea,arCOG04889@2157|Archaea,41SBG@651137|Thaumarchaeota	651137|Thaumarchaeota	FK	Anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,HTH_20,NRDD
YYD2_k127_6372337_0	203119.Cthe_2680	3.366e-26	119.0	COG0457@1|root,COG0457@2|Bacteria,1V076@1239|Firmicutes,25B8Z@186801|Clostridia,3WM09@541000|Ruminococcaceae	186801|Clostridia	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,TPR_1,TPR_2,TPR_8
YYD2_k127_6381661_1	1459636.NTE_03322	2.675e-139	454.0	COG0499@1|root,arCOG04137@2157|Archaea,41S9I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
YYD2_k127_6381661_0	1459636.NTE_03323	7.736e-246	771.0	COG0143@1|root,arCOG00810@2157|Archaea,41SAF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
YYD2_k127_6381661_2	1459636.NTE_03324	4.847e-09	57.0	COG1056@1|root,arCOG00972@2157|Archaea,41T2U@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cytidylyltransferase-like	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
YYD2_k127_6388921_0	1459636.NTE_03132	4.451e-143	463.0	COG0715@1|root,arCOG01803@2157|Archaea,41SG5@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
YYD2_k127_6392902_0	1459636.NTE_02036	3.253e-96	318.0	COG0422@1|root,arCOG02741@2157|Archaea,41S5Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Thiamine biosynthesis protein ThiC	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
YYD2_k127_6392902_1	1229909.NSED_08125	3.352e-44	168.0	COG0506@1|root,arCOG06322@2157|Archaea,41SY1@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
YYD2_k127_6394556_0	671143.DAMO_2372	4.189e-13	71.0	COG0778@1|root,COG0778@2|Bacteria,2NPP2@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
YYD2_k127_6400641_3	1459636.NTE_01189	2.791e-23	107.0	arCOG08028@1|root,arCOG08028@2157|Archaea,41SWE@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6400641_0	1459636.NTE_01188	2.331e-123	406.0	COG0520@1|root,arCOG00065@2157|Archaea,41SYH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YYD2_k127_6400641_2	1459636.NTE_01187	7.748e-39	145.0	COG1522@1|root,arCOG01117@2157|Archaea,41ST7@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
YYD2_k127_6400641_1	1459636.NTE_02716	1.845e-113	376.0	COG0430@1|root,arCOG04125@2157|Archaea,41T1K@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC
YYD2_k127_6408309_0	1459636.NTE_02763	1.543e-93	312.0	COG0602@1|root,arCOG02173@2157|Archaea,41SGM@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Radical_SAM
YYD2_k127_6408309_1	1229909.NSED_09825	7.807e-86	291.0	COG0603@1|root,arCOG00039@2157|Archaea,41SGR@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Queuosine biosynthesis protein QueC	-	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
YYD2_k127_6417216_0	1220534.B655_0556	9.44e-43	167.0	COG0067@1|root,arCOG00095@2157|Archaea,2XUF6@28890|Euryarchaeota,23PBU@183925|Methanobacteria	183925|Methanobacteria	E	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,GATase_7
YYD2_k127_6417216_1	1500259.JQLD01000010_gene4874	0.0007178	51.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,4BCY4@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Glutamate synthase central domain	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
YYD2_k127_6417692_1	1459636.NTE_02416	1.167e-19	92.0	COG0671@1|root,arCOG03056@2157|Archaea	2157|Archaea	I	PFAM phosphoesterase, PA-phosphatase related	sepP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
YYD2_k127_6417692_0	1459636.NTE_00422	6.318e-28	115.0	arCOG08799@1|root,arCOG08799@2157|Archaea,41T6M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6421525_3	1151117.AJLF01000002_gene17	4.391e-19	89.0	COG1727@1|root,arCOG00780@2157|Archaea,2XZ6R@28890|Euryarchaeota,2444E@183968|Thermococci	183968|Thermococci	J	Belongs to the eukaryotic ribosomal protein eL18 family	rpl18e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02883	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18
YYD2_k127_6421525_2	1459636.NTE_01336	3.669e-64	222.0	COG0102@1|root,arCOG04242@2157|Archaea,41SP4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rpl13	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YYD2_k127_6421525_1	1459636.NTE_01335	7.581e-68	233.0	COG0088@1|root,arCOG04243@2157|Archaea,41SKT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS9 family	-	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
YYD2_k127_6421525_0	1459636.NTE_01339	5.378e-83	279.0	COG1500@1|root,arCOG04187@2157|Archaea,41SC7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Shwachman-Bodian-Diamond syndrome (SBDS) protein	-	-	-	ko:K14574	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	SBDS,SBDS_C
YYD2_k127_6422504_0	397948.Cmaq_1851	1.215e-05	55.0	COG0589@1|root,arCOG02053@2157|Archaea,2XQTK@28889|Crenarchaeota	28889|Crenarchaeota	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD2_k127_6426339_0	1459636.NTE_00434	3.254e-229	724.0	COG1796@1|root,arCOG00305@2157|Archaea	2157|Archaea	L	DNA polymerase IV (family X)	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
YYD2_k127_6426339_3	471854.Dfer_2562	1.284e-08	63.0	COG2323@1|root,COG2323@2|Bacteria,4NSMY@976|Bacteroidetes,47RV4@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
YYD2_k127_6427373_3	443255.SCLAV_1862	8.541e-09	66.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	quiC	-	4.2.1.118	ko:K09483	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R01627	RC00568	ko00000,ko00001,ko01000	-	-	-	Beta_helix,CHU_C,NosD
YYD2_k127_6427373_1	1229909.NSED_03480	1.716e-19	96.0	COG0517@1|root,arCOG00606@2157|Archaea	2157|Archaea	I	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YYD2_k127_6427373_0	344747.PM8797T_02494	1.986e-132	431.0	COG2130@1|root,COG2130@2|Bacteria,2IY4S@203682|Planctomycetes	203682|Planctomycetes	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
YYD2_k127_6427373_2	1459636.NTE_02333	8.395e-11	68.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6428189_0	671065.MetMK1DRAFT_00005530	1.215e-47	181.0	COG0235@1|root,arCOG04226@2157|Archaea,2XQGF@28889|Crenarchaeota	28889|Crenarchaeota	G	Class II aldolase adducin family protein	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
YYD2_k127_6428189_1	399549.Msed_0930	2.161e-29	120.0	COG0409@1|root,arCOG04428@2157|Archaea,2XPKY@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM hydrogenase formation HypD protein	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
YYD2_k127_6428494_1	1459636.NTE_00813	3.671e-57	208.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YYD2_k127_6428494_2	1459636.NTE_00354	3.604e-55	201.0	COG1777@1|root,arCOG01684@2157|Archaea	2157|Archaea	K	transcriptional	-	-	-	ko:K07721	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5,TrmB
YYD2_k127_6428494_0	1459636.NTE_00355	3.348e-131	424.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	2157|Archaea	O	PFAM TCP-1 cpn60 chaperonin family	thsA	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
YYD2_k127_6428494_3	1459636.NTE_00355	3.595e-10	63.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	2157|Archaea	O	PFAM TCP-1 cpn60 chaperonin family	thsA	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
YYD2_k127_6430891_0	436308.Nmar_0408	2.761e-33	136.0	arCOG08670@1|root,arCOG08670@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
YYD2_k127_6431873_0	436308.Nmar_0008	7.494e-94	332.0	COG1252@1|root,arCOG01067@2157|Archaea	2157|Archaea	C	COG1252 NADH dehydrogenase, FAD-containing subunit	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YYD2_k127_646319_0	1459636.NTE_01332	1.067e-92	318.0	COG0477@1|root,arCOG00130@2157|Archaea	2157|Archaea	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD2_k127_646897_4	1459636.NTE_02264	2.242e-63	221.0	COG1304@1|root,arCOG00613@2157|Archaea	2157|Archaea	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
YYD2_k127_646897_3	1459636.NTE_02265	4.587e-106	353.0	COG0142@1|root,arCOG01726@2157|Archaea,41SEV@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
YYD2_k127_646897_0	1459636.NTE_02266	5.319e-215	681.0	COG0008@1|root,arCOG04302@2157|Archaea,41S5V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
YYD2_k127_646897_1	1459636.NTE_02267	5.733e-130	420.0	COG0179@1|root,arCOG00235@2157|Archaea,41S5K@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
YYD2_k127_646897_2	1459636.NTE_02274	1.429e-113	370.0	COG1018@1|root,arCOG02200@2157|Archaea,41S72@651137|Thaumarchaeota	651137|Thaumarchaeota	C	oxidoreductase FAD NAD(P)-binding	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
YYD2_k127_666737_0	436308.Nmar_0977	6.071e-125	414.0	COG0702@1|root,arCOG03015@2157|Archaea	2157|Archaea	GM	NAD-dependent epimerase dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_10
YYD2_k127_669370_0	1459636.NTE_01048	4.088e-151	486.0	COG0624@1|root,arCOG01110@2157|Archaea,41SAE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YYD2_k127_672808_0	1459636.NTE_02628	2.417e-06	53.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_02628|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_675094_0	247490.KSU1_C1274	7.83e-30	128.0	COG1409@1|root,COG3534@1|root,COG1409@2|Bacteria,COG3534@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
YYD2_k127_67741_1	1459636.NTE_00468	1.333e-06	49.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea	2157|Archaea	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1,sCache_3_3
YYD2_k127_67741_0	1459636.NTE_02123	3.942e-84	302.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea	2157|Archaea	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1,sCache_3_3
YYD2_k127_685495_0	591001.Acfer_0436	4.794e-20	94.0	COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,4H4ZK@909932|Negativicutes	909932|Negativicutes	T	Belongs to the universal stress protein A family	usp22	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD2_k127_686230_0	1459636.NTE_03244	6.835e-73	258.0	COG1237@1|root,arCOG00503@2157|Archaea	2157|Archaea	S	PFAM beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Lactamase_B_2
YYD2_k127_694204_0	1459636.NTE_00991	2.46e-19	97.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_00991|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_704172_1	436308.Nmar_1796	4.781e-14	77.0	arCOG08806@1|root,arCOG08806@2157|Archaea,41SUU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_704172_2	1459636.NTE_00082	1.339e-12	76.0	arCOG08041@1|root,arCOG08041@2157|Archaea,41SRT@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
YYD2_k127_704172_0	1459636.NTE_00084	2.171e-43	161.0	COG1474@1|root,arCOG00467@2157|Archaea,41SED@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22,Cdc6_C
YYD2_k127_707645_1	1459636.NTE_03331	2.536e-14	76.0	COG0023@1|root,arCOG04223@2157|Archaea	2157|Archaea	J	Belongs to the SUI1 family	tif1a	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
YYD2_k127_707645_0	1459636.NTE_03330	6.264e-118	387.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	2157|Archaea	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YYD2_k127_707849_0	1459636.NTE_01508	2.169e-09	64.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_711809_0	1121405.dsmv_3740	0.000752	48.0	COG0427@1|root,COG0454@1|root,COG0427@2|Bacteria,COG0456@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
YYD2_k127_726722_0	931626.Awo_c07350	1.185e-59	218.0	COG0596@1|root,COG0596@2|Bacteria,1VRHA@1239|Firmicutes,24PCH@186801|Clostridia	186801|Clostridia	S	Hydrolase, alpha beta domain protein	mhpC	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
YYD2_k127_726722_1	1094980.Mpsy_0004	1.412e-09	61.0	arCOG11428@1|root,arCOG11428@2157|Archaea,2Y53W@28890|Euryarchaeota,2NBAB@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_7334_0	1167006.UWK_03221	2.918e-13	79.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42PQZ@68525|delta/epsilon subdivisions,2WMD9@28221|Deltaproteobacteria,2MNAP@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Hemolysin-type calcium-binding	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HCBP_related,He_PIG,HemolysinCabind,Peptidase_M91,VWA_2
YYD2_k127_740247_0	1499685.CCFJ01000012_gene1884	2.96e-14	78.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,1ZCRU@1386|Bacillus	91061|Bacilli	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_742518_0	1041930.Mtc_1620	2.535e-62	219.0	COG2217@1|root,COG3350@1|root,arCOG01576@2157|Archaea,arCOG04507@2157|Archaea,2XT3T@28890|Euryarchaeota,2N94W@224756|Methanomicrobia	224756|Methanomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
YYD2_k127_747310_1	1459636.NTE_02880	7.618e-73	252.0	COG0150@1|root,arCOG00639@2157|Archaea,41SEE@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YYD2_k127_747310_0	1459636.NTE_02878	1.37e-233	733.0	COG1384@1|root,arCOG00485@2157|Archaea,41SB4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
YYD2_k127_747310_2	1131266.ARWQ01000006_gene216	5.929e-17	81.0	COG1243@1|root,arCOG01361@2157|Archaea,41S9N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Histone acetyltransferase	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
YYD2_k127_749079_1	1459636.NTE_02057	1.575e-39	151.0	COG2007@1|root,arCOG04154@2157|Archaea,41SP2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein S8e	rps8e	-	-	ko:K02995	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8e
YYD2_k127_749079_2	1459636.NTE_02055	9.136e-30	121.0	COG1400@1|root,arCOG01217@2157|Archaea,41SR5@651137|Thaumarchaeota	651137|Thaumarchaeota	U	SRP19 protein	-	-	-	ko:K03105	ko03060,map03060	-	-	-	ko00000,ko00001,ko02044	3.A.5.7,3.A.5.9	-	-	SRP19
YYD2_k127_749079_3	1459636.NTE_02054	1.134e-13	74.0	COG3277@1|root,arCOG02466@2157|Archaea,41SVG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA-binding protein involved in rRNA processing	-	-	-	ko:K07569	-	-	-	-	ko00000,ko03009	-	-	-	Gar1
YYD2_k127_749079_0	1459636.NTE_02053	5.86e-66	229.0	COG1405@1|root,arCOG01981@2157|Archaea,41S8Y@651137|Thaumarchaeota	651137|Thaumarchaeota	K	factor TFIIB	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
YYD2_k127_752107_0	1459636.NTE_02889	5.641e-199	628.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	2157|Archaea	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
YYD2_k127_752107_2	1459636.NTE_02887	5.057e-41	157.0	arCOG06188@1|root,arCOG06188@2157|Archaea,41STJ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	UreE urease accessory protein, N-terminal domain	-	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
YYD2_k127_752107_1	1459636.NTE_02886	2.88e-59	213.0	COG0830@1|root,arCOG04530@2157|Archaea,41SG4@651137|Thaumarchaeota	651137|Thaumarchaeota	O	UreF	-	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
YYD2_k127_759904_0	1459636.NTE_00649	1.173e-148	479.0	COG2237@1|root,arCOG04151@2157|Archaea,41SA3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF373)	-	-	-	ko:K08975	-	-	-	-	ko00000	-	-	-	DUF373
YYD2_k127_759904_1	1459636.NTE_00400	1.112e-110	363.0	COG0020@1|root,arCOG01532@2157|Archaea,41S8J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids	uppS	-	2.5.1.89	ko:K15888	ko00900,map00900	-	R09730	RC00279,RC02839	ko00000,ko00001,ko01000	-	-	-	Prenyltransf
YYD2_k127_759904_5	1459636.NTE_00652	7.547e-37	143.0	COG0494@1|root,arCOG01078@2157|Archaea,41SPS@651137|Thaumarchaeota	651137|Thaumarchaeota	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD2_k127_759904_7	1459636.NTE_00639	2.45e-19	91.0	arCOG08702@1|root,arCOG08702@2157|Archaea,41ST2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_759904_3	1459636.NTE_00640	7.361e-43	160.0	arCOG08703@1|root,arCOG08703@2157|Archaea,41SS0@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_759904_6	1459636.NTE_00641	2.083e-24	105.0	arCOG08704@1|root,arCOG08704@2157|Archaea,41STG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_759904_2	1459636.NTE_00642	1.592e-110	362.0	COG0005@1|root,arCOG01327@2157|Archaea,41SDR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YYD2_k127_759904_4	1459636.NTE_00643	1.574e-42	158.0	COG0503@1|root,arCOG00030@2157|Archaea,41SMR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
YYD2_k127_763528_0	1459636.NTE_00833	2.331e-71	245.0	COG0778@1|root,arCOG00288@2157|Archaea,41S7D@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Cob(II)yrinic acid a,c-diamide reductase	-	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
YYD2_k127_763528_1	1459636.NTE_00648	1.25e-53	192.0	COG0293@1|root,arCOG00079@2157|Archaea,41SIK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	rlmE	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
YYD2_k127_763944_1	1128427.KB904821_gene815	6.424e-05	50.0	COG3842@1|root,COG3842@2|Bacteria,1G0FR@1117|Cyanobacteria,1H70J@1150|Oscillatoriales	1117|Cyanobacteria	E	Carbohydrate ABC transporter ATP-binding protein, CUT1 family	-	-	-	ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
YYD2_k127_763944_0	500633.CLOHIR_02218	3.067e-13	76.0	COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,24MNT@186801|Clostridia,25TEH@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YYD2_k127_764010_0	1459636.NTE_02584	2.307e-66	234.0	COG1028@1|root,arCOG01259@2157|Archaea,41SXY@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YYD2_k127_764010_1	1459636.NTE_01573	4.216e-18	87.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
YYD2_k127_768456_0	1459636.NTE_02333	2.302e-14	76.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_778280_0	1459636.NTE_00043	1.15e-120	392.0	COG1117@1|root,arCOG00231@2157|Archaea,41SYJ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
YYD2_k127_778479_0	1304885.AUEY01000014_gene3322	2.404e-85	299.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2WQM8@28221|Deltaproteobacteria,2MKXA@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	B_lectin,Inhibitor_I9,Peptidase_S8,Somatomedin_B
YYD2_k127_781102_0	1459636.NTE_03481	1.865e-166	544.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
YYD2_k127_781102_2	1439940.BAY1663_04951	1.359e-15	78.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
YYD2_k127_781102_3	102125.Xen7305DRAFT_00050910	1.488e-07	62.0	COG2931@1|root,COG2931@2|Bacteria,1G69X@1117|Cyanobacteria,3VK01@52604|Pleurocapsales	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lectin_C
YYD2_k127_781102_1	357808.RoseRS_1673	3.29e-24	112.0	COG1470@1|root,COG1716@1|root,COG1470@2|Bacteria,COG1716@2|Bacteria,2G8JT@200795|Chloroflexi	200795|Chloroflexi	T	FHA domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
YYD2_k127_785278_1	1459636.NTE_02854	3.091e-25	107.0	COG0614@1|root,arCOG04233@2157|Archaea,41SXD@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
YYD2_k127_785278_0	1459636.NTE_01649	2.173e-44	169.0	COG1280@1|root,arCOG01947@2157|Archaea,41T36@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Lysine exporter protein LysE YggA	-	-	-	-	-	-	-	-	-	-	-	-	LysE
YYD2_k127_789975_0	1541960.KQ78_01934	1.728e-22	102.0	COG4186@1|root,COG4186@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
YYD2_k127_800778_2	1459636.NTE_01850	7.448e-10	61.0	COG1028@1|root,arCOG01259@2157|Archaea,41S7V@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YYD2_k127_800778_1	1459636.NTE_03022	1.168e-36	148.0	COG5491@1|root,arCOG00452@2157|Archaea	2157|Archaea	N	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	Snf7
YYD2_k127_800778_0	1459636.NTE_03023	1.512e-85	302.0	COG1378@1|root,arCOG02038@2157|Archaea	2157|Archaea	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
YYD2_k127_808088_0	1229909.NSED_00425	6.84e-06	57.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YYD2_k127_811350_1	1459636.NTE_00832	5.217e-86	295.0	arCOG08801@1|root,arCOG08801@2157|Archaea	2157|Archaea	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_811350_2	1459636.NTE_01064	1.225e-16	83.0	COG0640@1|root,arCOG03067@2157|Archaea,41T7Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_811350_0	1459636.NTE_02742	3.498e-173	549.0	COG0672@1|root,arCOG04330@2157|Archaea,41T07@651137|Thaumarchaeota	651137|Thaumarchaeota	P	High-affinity Fe2 Pb2 permease	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
YYD2_k127_817598_0	1128421.JAGA01000002_gene335	2.24e-33	134.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
YYD2_k127_824177_5	1459636.NTE_03198	7.751e-18	87.0	COG0546@1|root,arCOG04692@2157|Archaea,41SJ6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
YYD2_k127_824177_2	1459636.NTE_03201	1.517e-75	258.0	COG0131@1|root,arCOG04398@2157|Archaea,41SGY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
YYD2_k127_824177_1	1459636.NTE_03202	8.107e-84	282.0	COG0118@1|root,arCOG00089@2157|Archaea,41SY2@651137|Thaumarchaeota	651137|Thaumarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YYD2_k127_824177_3	1459636.NTE_03203	4.352e-73	253.0	COG0106@1|root,arCOG00618@2157|Archaea,41SIG@651137|Thaumarchaeota	651137|Thaumarchaeota	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YYD2_k127_824177_0	1459636.NTE_03204	1.842e-123	401.0	COG0107@1|root,arCOG00617@2157|Archaea,41S9A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YYD2_k127_824177_4	1459636.NTE_00723	4.729e-39	145.0	COG0361@1|root,arCOG01179@2157|Archaea,41SRK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits	-	-	-	ko:K03236	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	eIF-1a
YYD2_k127_833411_4	1459636.NTE_01183	5.113e-07	57.0	COG0582@1|root,arCOG01242@2157|Archaea	2157|Archaea	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase,zinc_ribbon_2
YYD2_k127_833411_2	1459636.NTE_02527	2.229e-52	194.0	COG0819@1|root,arCOG01128@2157|Archaea,41TB7@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	-
YYD2_k127_833411_3	1459636.NTE_02548	5.258e-18	87.0	COG0142@1|root,arCOG01727@2157|Archaea,41SC6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
YYD2_k127_833411_0	1459636.NTE_02548	7.473e-84	284.0	COG0142@1|root,arCOG01727@2157|Archaea,41SC6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
YYD2_k127_840463_2	1128421.JAGA01000002_gene335	5.444e-118	394.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
YYD2_k127_840463_5	1459636.NTE_00669	4.609e-14	82.0	COG3685@1|root,arCOG11147@2157|Archaea	2157|Archaea	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
YYD2_k127_840463_4	373994.Riv7116_0738	7.405e-45	166.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
YYD2_k127_840463_3	1459636.NTE_02294	2.173e-56	200.0	COG1321@1|root,arCOG02100@2157|Archaea,41SQ9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
YYD2_k127_840463_1	1459636.NTE_01396	1.314e-137	451.0	COG0428@1|root,arCOG00576@2157|Archaea,41S6R@651137|Thaumarchaeota	651137|Thaumarchaeota	P	divalent heavy-metal cations transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_840463_0	1459636.NTE_01395	5.699e-152	490.0	COG2132@1|root,arCOG03914@2157|Archaea,41S77@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	PFAM Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
YYD2_k127_841114_1	319795.Dgeo_2444	7.767e-12	74.0	COG0672@1|root,COG0672@2|Bacteria	2|Bacteria	P	high-affinity ferrous iron transmembrane transporter activity	efeU_1	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
YYD2_k127_841114_0	1459636.NTE_01061	2.403e-21	104.0	arCOG10358@1|root,arCOG10358@2157|Archaea,41SYI@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_846811_0	694429.Pyrfu_0117	1.314e-29	123.0	COG1913@1|root,arCOG00458@2157|Archaea,2XQRN@28889|Crenarchaeota	28889|Crenarchaeota	O	zinc metalloprotease whose natural substrate is	amzA	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
YYD2_k127_849435_0	1459636.NTE_00004	1.888e-05	50.0	COG0468@1|root,arCOG00415@2157|Archaea	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	-	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
YYD2_k127_849435_1	596323.HMPREF0554_1066	0.0009263	49.0	COG1196@1|root,COG1196@2|Bacteria,37848@32066|Fusobacteria	32066|Fusobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YYD2_k127_8511_0	1459636.NTE_02485	2.345e-114	381.0	COG0322@1|root,arCOG04753@2157|Archaea,41SX9@651137|Thaumarchaeota	651137|Thaumarchaeota	L	TIGRFAM excinuclease ABC, C subunit	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
YYD2_k127_861255_0	1459636.NTE_01902	2.51e-216	677.0	COG1503@1|root,arCOG01742@2157|Archaea,41SEK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA	prf1	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_1,eRF1_2,eRF1_3
YYD2_k127_862744_0	1459636.NTE_02800	2.752e-145	466.0	COG0039@1|root,arCOG00246@2157|Archaea,41S7Z@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the LDH MDH superfamily	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
YYD2_k127_862744_1	436308.Nmar_0337	2.018e-24	108.0	COG1691@1|root,arCOG02465@2157|Archaea,41SCY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
YYD2_k127_864714_1	1227495.C487_19678	1.155e-05	52.0	COG3316@1|root,arCOG02134@2157|Archaea,2XV05@28890|Euryarchaeota,23T31@183963|Halobacteria	183963|Halobacteria	L	COG3316 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
YYD2_k127_864714_0	858215.Thexy_1133	6.193e-82	285.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,249RZ@186801|Clostridia,42F2C@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3,Sugar_tr
YYD2_k127_871124_1	1459636.NTE_01754	2.621e-11	68.0	COG0608@1|root,arCOG00427@2157|Archaea,41SZF@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
YYD2_k127_871124_0	1459636.NTE_01756	3.952e-138	447.0	COG0172@1|root,arCOG00403@2157|Archaea,41SC9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YYD2_k127_872181_0	211165.AJLN01000055_gene4549	2.981e-129	419.0	28HGI@1|root,2Z7SC@2|Bacteria,1FZZQ@1117|Cyanobacteria,1JHV5@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_876472_0	649638.Trad_0598	3.901e-91	319.0	COG1199@1|root,COG1199@2|Bacteria	2|Bacteria	L	ATP-dependent helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DEAD_2,Helicase_C_2
YYD2_k127_878385_1	985255.APHJ01000054_gene1892	1.059e-05	53.0	COG0745@1|root,COG0745@2|Bacteria,4NR6P@976|Bacteroidetes,1I2SQ@117743|Flavobacteriia,2P7PA@244698|Gillisia	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD2_k127_878385_0	1267533.KB906736_gene1024	1.297e-13	78.0	arCOG11428@1|root,33YIA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_886583_0	574375.BAGA_15080	0.0002911	52.0	COG0745@1|root,COG0745@2|Bacteria,1TX0Q@1239|Firmicutes,4HEF8@91061|Bacilli,1ZBAA@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_889276_6	1459636.NTE_03198	1.975e-64	229.0	COG0546@1|root,arCOG04692@2157|Archaea,41SJ6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
YYD2_k127_889276_5	1459636.NTE_03197	1.09e-87	301.0	COG0079@1|root,arCOG04273@2157|Archaea,41SGB@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD2_k127_889276_4	1229909.NSED_00715	5.843e-123	407.0	COG0141@1|root,arCOG04352@2157|Archaea,41S6J@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
YYD2_k127_889276_0	1459636.NTE_03195	8.344e-159	505.0	COG0040@1|root,arCOG02208@2157|Archaea,41SCJ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ATP phosphoribosyltransferase	-	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
YYD2_k127_889276_1	1459636.NTE_03194	1.421e-146	476.0	COG1257@1|root,arCOG04260@2157|Archaea,41SAU@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the HMG-CoA reductase family	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
YYD2_k127_889276_3	1459636.NTE_03188	1.354e-142	461.0	COG2133@1|root,arCOG02796@2157|Archaea,41S7F@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD2_k127_889276_2	1459636.NTE_03161	9.918e-144	464.0	COG0399@1|root,arCOG00118@2157|Archaea,41S96@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YYD2_k127_889276_7	1459636.NTE_03162	2.102e-46	171.0	COG0004@1|root,arCOG04397@2157|Archaea,41SZ0@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
YYD2_k127_903045_0	1459636.NTE_00441	3.241e-49	186.0	COG0454@1|root,arCOG00845@2157|Archaea,41T5Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD2_k127_932404_0	521011.Mpal_1345	6.475e-75	263.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
YYD2_k127_994081_0	1459636.NTE_00429	2.534e-05	52.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 2130 queries scanned
## Total time (seconds): 3.9566924571990967
## Rate: 538.33 q/s